LOCUS       DAJSMK010000001        90899 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.001, whole genome shotgun sequence.
ACCESSION   DAJSMK010000001 DAJSMK010000000
VERSION     DAJSMK010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 90899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.001"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            26..1084
                     /locus_tag="ON488_000001"
     CDS             26..1084
                     /locus_tag="ON488_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HCR3230228.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1088..2122
                     /locus_tag="ON488_000002"
     CDS             1088..2122
                     /locus_tag="ON488_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HCR3230229.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2224..2940)
                     /locus_tag="ON488_000003"
     CDS             complement(2224..2940)
                     /locus_tag="ON488_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCR3230230.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(2909..3694)
                     /locus_tag="ON488_000004"
     CDS             complement(2909..3694)
                     /locus_tag="ON488_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HCR3230231.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3685..4434)
                     /locus_tag="ON488_000005"
     CDS             complement(3685..4434)
                     /locus_tag="ON488_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCR3230232.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4732..5256
                     /locus_tag="ON488_000006"
     CDS             4732..5256
                     /locus_tag="ON488_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HCR3230233.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5272..6771
                     /locus_tag="ON488_000007"
     CDS             5272..6771
                     /locus_tag="ON488_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HCR3230234.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6859..7461)
                     /locus_tag="ON488_000008"
     CDS             complement(6859..7461)
                     /locus_tag="ON488_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCR3230235.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7565..8521
                     /locus_tag="ON488_000009"
     CDS             7565..8521
                     /locus_tag="ON488_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HCR3230236.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8826..9782)
                     /locus_tag="ON488_000010"
     CDS             complement(8826..9782)
                     /locus_tag="ON488_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR3230237.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            9956..10516
                     /locus_tag="ON488_000011"
     CDS             9956..10516
                     /locus_tag="ON488_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230238.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10509..11333
                     /locus_tag="ON488_000012"
     CDS             10509..11333
                     /locus_tag="ON488_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HCR3230239.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11343..11960
                     /locus_tag="ON488_000013"
     CDS             11343..11960
                     /locus_tag="ON488_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCR3230240.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            11978..12661
                     /locus_tag="ON488_000014"
     CDS             11978..12661
                     /locus_tag="ON488_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCR3230241.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13344..14627
                     /locus_tag="ON488_000015"
     CDS             13344..14627
                     /locus_tag="ON488_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3230242.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14643..15530
                     /locus_tag="ON488_000016"
     CDS             14643..15530
                     /locus_tag="ON488_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3230243.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15547..16383
                     /locus_tag="ON488_000017"
     CDS             15547..16383
                     /locus_tag="ON488_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3230244.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16386..17009
                     /locus_tag="ON488_000018"
     CDS             16386..17009
                     /locus_tag="ON488_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230245.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17006..18298
                     /locus_tag="ON488_000019"
     CDS             17006..18298
                     /locus_tag="ON488_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR3230246.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18657..18754
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18870..19451
                     /locus_tag="ON488_000020"
     CDS             18870..19451
                     /locus_tag="ON488_000020"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HCR3230247.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19454..20761
                     /locus_tag="ON488_000021"
     CDS             19454..20761
                     /locus_tag="ON488_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HCR3230248.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21177..21665
                     /gene="purE"
                     /locus_tag="ON488_000022"
     CDS             21177..21665
                     /gene="purE"
                     /locus_tag="ON488_000022"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HCR3230249.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21658..22782
                     /gene="purK"
                     /locus_tag="ON488_000023"
     CDS             21658..22782
                     /gene="purK"
                     /locus_tag="ON488_000023"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HCR3230250.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22795..24090
                     /gene="purB"
                     /locus_tag="ON488_000024"
     CDS             22795..24090
                     /gene="purB"
                     /locus_tag="ON488_000024"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HCR3230251.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24270..24647)
                     /locus_tag="ON488_000025"
     CDS             complement(24270..24647)
                     /locus_tag="ON488_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230252.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            24903..25631
                     /locus_tag="ON488_000026"
     CDS             24903..25631
                     /locus_tag="ON488_000026"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HCR3230253.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            25631..25885
                     /gene="purS"
                     /locus_tag="ON488_000027"
     CDS             25631..25885
                     /gene="purS"
                     /locus_tag="ON488_000027"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HCR3230254.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            25887..26558
                     /gene="purQ"
                     /locus_tag="ON488_000028"
     CDS             25887..26558
                     /gene="purQ"
                     /locus_tag="ON488_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HCR3230255.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            26559..28781
                     /gene="purL"
                     /locus_tag="ON488_000029"
     CDS             26559..28781
                     /gene="purL"
                     /locus_tag="ON488_000029"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HCR3230256.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            28766..30205
                     /locus_tag="ON488_000030"
     CDS             28766..30205
                     /locus_tag="ON488_000030"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HCR3230257.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            30228..31280
                     /locus_tag="ON488_000031"
     CDS             30228..31280
                     /locus_tag="ON488_000031"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HCR3230258.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            31277..31855
                     /gene="purN"
                     /locus_tag="ON488_000032"
     CDS             31277..31855
                     /gene="purN"
                     /locus_tag="ON488_000032"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HCR3230259.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            31852..33387
                     /gene="purH"
                     /locus_tag="ON488_000033"
     CDS             31852..33387
                     /gene="purH"
                     /locus_tag="ON488_000033"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HCR3230260.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            33403..34677
                     /gene="purD"
                     /locus_tag="ON488_000034"
     CDS             33403..34677
                     /gene="purD"
                     /locus_tag="ON488_000034"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HCR3230261.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            34799..35713
                     /locus_tag="ON488_000035"
     CDS             34799..35713
                     /locus_tag="ON488_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCR3230262.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(35846..37411)
                     /locus_tag="ON488_000036"
     CDS             complement(35846..37411)
                     /locus_tag="ON488_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCR3230263.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(37404..38855)
                     /locus_tag="ON488_000037"
     CDS             complement(37404..38855)
                     /locus_tag="ON488_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCR3230264.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(38869..39885)
                     /locus_tag="ON488_000038"
     CDS             complement(38869..39885)
                     /locus_tag="ON488_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3230265.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            40105..41193
                     /locus_tag="ON488_000039"
     CDS             40105..41193
                     /locus_tag="ON488_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HCR3230266.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            41247..42773
                     /locus_tag="ON488_000040"
     CDS             41247..42773
                     /locus_tag="ON488_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HCR3230267.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            42775..43980
                     /locus_tag="ON488_000041"
     CDS             42775..43980
                     /locus_tag="ON488_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3230268.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            44237..45214
                     /gene="guaC"
                     /locus_tag="ON488_000042"
     CDS             44237..45214
                     /gene="guaC"
                     /locus_tag="ON488_000042"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HCR3230269.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            45478..46902
                     /locus_tag="ON488_000043"
     CDS             45478..46902
                     /locus_tag="ON488_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCR3230270.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            47363..48472
                     /gene="pdhA"
                     /locus_tag="ON488_000044"
     CDS             47363..48472
                     /gene="pdhA"
                     /locus_tag="ON488_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HCR3230271.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            48475..49452
                     /locus_tag="ON488_000045"
     CDS             48475..49452
                     /locus_tag="ON488_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HCR3230272.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            49477..51120
                     /locus_tag="ON488_000046"
     CDS             49477..51120
                     /locus_tag="ON488_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HCR3230273.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            51128..52534
                     /gene="lpdA"
                     /locus_tag="ON488_000047"
     CDS             51128..52534
                     /gene="lpdA"
                     /locus_tag="ON488_000047"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HCR3230274.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            52696..52971
                     /locus_tag="ON488_000048"
     CDS             52696..52971
                     /locus_tag="ON488_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HCR3230275.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            52977..53744
                     /locus_tag="ON488_000049"
     CDS             52977..53744
                     /locus_tag="ON488_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HCR3230276.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            53912..55741
                     /gene="typA"
                     /locus_tag="ON488_000050"
     CDS             53912..55741
                     /gene="typA"
                     /locus_tag="ON488_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HCR3230277.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            56002..57774
                     /gene="recQ"
                     /locus_tag="ON488_000051"
     CDS             56002..57774
                     /gene="recQ"
                     /locus_tag="ON488_000051"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HCR3230278.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            57888..58190
                     /locus_tag="ON488_000052"
     CDS             57888..58190
                     /locus_tag="ON488_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HCR3230279.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            58193..59356
                     /locus_tag="ON488_000053"
     CDS             58193..59356
                     /locus_tag="ON488_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCR3230280.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            59382..62810
                     /locus_tag="ON488_000054"
     CDS             59382..62810
                     /locus_tag="ON488_000054"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HCR3230281.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            62831..63955
                     /locus_tag="ON488_000055"
     CDS             62831..63955
                     /locus_tag="ON488_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230282.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            63945..64382
                     /locus_tag="ON488_000056"
     CDS             63945..64382
                     /locus_tag="ON488_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCR3230283.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            64366..64704
                     /locus_tag="ON488_000057"
     CDS             64366..64704
                     /locus_tag="ON488_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HCR3230284.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            64823..65383
                     /gene="rsmD"
                     /locus_tag="ON488_000058"
     CDS             64823..65383
                     /gene="rsmD"
                     /locus_tag="ON488_000058"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HCR3230285.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            65380..65871
                     /gene="coaD"
                     /locus_tag="ON488_000059"
     CDS             65380..65871
                     /gene="coaD"
                     /locus_tag="ON488_000059"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HCR3230286.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            65861..66904
                     /locus_tag="ON488_000060"
     CDS             65861..66904
                     /locus_tag="ON488_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HCR3230287.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            67063..67791
                     /locus_tag="ON488_000061"
     CDS             67063..67791
                     /locus_tag="ON488_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HCR3230288.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            67907..68152
                     /locus_tag="ON488_000062"
     CDS             67907..68152
                     /locus_tag="ON488_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCR3230289.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            68149..68367
                     /locus_tag="ON488_000063"
     CDS             68149..68367
                     /locus_tag="ON488_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HCR3230290.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            68503..69042
                     /locus_tag="ON488_000064"
     CDS             68503..69042
                     /locus_tag="ON488_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HCR3230291.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            69035..71308
                     /locus_tag="ON488_000065"
     CDS             69035..71308
                     /locus_tag="ON488_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HCR3230292.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            71346..72392
                     /gene="holA"
                     /locus_tag="ON488_000066"
     CDS             71346..72392
                     /gene="holA"
                     /locus_tag="ON488_000066"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HCR3230293.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(72481..72735)
                     /locus_tag="ON488_000067"
     CDS             complement(72481..72735)
                     /locus_tag="ON488_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HCR3230294.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(73135..73404)
                     /locus_tag="ON488_000068"
     CDS             complement(73135..73404)
                     /locus_tag="ON488_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230295.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(73874..74329)
                     /locus_tag="ON488_000069"
     CDS             complement(73874..74329)
                     /locus_tag="ON488_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HCR3230296.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(74467..76395)
                     /locus_tag="ON488_000070"
     CDS             complement(74467..76395)
                     /locus_tag="ON488_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HCR3230297.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(76592..77425)
                     /locus_tag="ON488_000071"
     CDS             complement(76592..77425)
                     /locus_tag="ON488_000071"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HCR3230298.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(77617..78321)
                     /locus_tag="ON488_000072"
     CDS             complement(77617..78321)
                     /locus_tag="ON488_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCR3230299.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(78344..78970)
                     /locus_tag="ON488_000073"
     CDS             complement(78344..78970)
                     /locus_tag="ON488_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR3230300.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            79296..81671
                     /locus_tag="ON488_000074"
     CDS             79296..81671
                     /locus_tag="ON488_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HCR3230301.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(81695..82186)
                     /locus_tag="ON488_000075"
     CDS             complement(81695..82186)
                     /locus_tag="ON488_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HCR3230302.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            82373..83293
                     /locus_tag="ON488_000076"
     CDS             82373..83293
                     /locus_tag="ON488_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCR3230303.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            83447..83791
                     /locus_tag="ON488_000077"
     CDS             83447..83791
                     /locus_tag="ON488_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HCR3230304.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(83981..84481)
                     /locus_tag="ON488_000078"
     CDS             complement(83981..84481)
                     /locus_tag="ON488_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3230305.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            85009..85092
                     /locus_tag="ON488_000079"
     tRNA            85009..85092
                     /locus_tag="ON488_000079"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:85043..85045,aa:Leu,seq:cag)
     gene            complement(85416..86054)
                     /locus_tag="ON488_000080"
     CDS             complement(85416..86054)
                     /locus_tag="ON488_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCR3230306.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            86389..86823
                     /locus_tag="ON488_000081"
     CDS             86389..86823
                     /locus_tag="ON488_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCR3230307.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            86846..87166
                     /locus_tag="ON488_000082"
     CDS             86846..87166
                     /locus_tag="ON488_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230308.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            87307..87498
                     /locus_tag="ON488_000083"
     CDS             87307..87498
                     /locus_tag="ON488_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230309.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(87569..87826)
                     /locus_tag="ON488_000084"
     CDS             complement(87569..87826)
                     /locus_tag="ON488_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HCR3230310.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            87984..88247
                     /locus_tag="ON488_000085"
     CDS             87984..88247
                     /locus_tag="ON488_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230311.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            88271..88459
                     /locus_tag="ON488_000086"
     CDS             88271..88459
                     /locus_tag="ON488_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230312.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(88542..88727)
                     /locus_tag="ON488_000087"
     CDS             complement(88542..88727)
                     /locus_tag="ON488_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230313.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            88942..89313
                     /locus_tag="ON488_000088"
     CDS             88942..89313
                     /locus_tag="ON488_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCR3230314.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(89463..89535)
                     /locus_tag="ON488_000089"
     tRNA            complement(89463..89535)
                     /locus_tag="ON488_000089"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(89500..89502),aa:Gln,seq:ctg)
     gene            complement(89581..90009)
                     /locus_tag="ON488_000090"
     CDS             complement(89581..90009)
                     /locus_tag="ON488_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230315.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(90069..90827)
                     /locus_tag="ON488_000091"
     CDS             complement(90069..90827)
                     /locus_tag="ON488_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HCR3230316.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT        29575 a        15659 c        19415 g        26250 t
ORIGIN      
        1 aatgaacata attaggagga gaaagatgaa cttatttgac atttttcgat cgactttgac
       61 agatatgtcg attgtcagtg caatcacttc aacagttttt attatattat tagggtttgt
      121 ttgtagaaaa aaggggattt tttctgaatc tgttggaaaa attctatcga aagtcgtctt
      181 aacagtggct ttgccagcac tggcatttcg agctttcatg caagatatca atacagaatt
      241 actgatgcaa ggaatcaatg tcttgatttg gggattagtt atttatatta ttcttattct
      301 agtttcaaaa ccttttttct taagctataa aggggataag caaacaacgt tgcgtgtcct
      361 gacgatcttt ggttctacga cctttttcgg aacgcctatc gtcagtgcga tttatggtcc
      421 tgtcggcgtg atgtattcct caattttcaa tattggctac cgaatctttt tgtattctta
      481 tggatacata aaaatgagtg gcttgaagat ggaagctaaa aatatcaaag cgatgttcgt
      541 caatccaatc attatcgcta cttttgccgg ccttttcatt tggctgttcc aagggtatct
      601 gccacaagtg tcagttacag gtgcagaagg agagataagc caagtagcgt ttttgcgaat
      661 tgaccagact gcaccgtggc tatttcagcc gatggattat ttagctggtt taagttcacc
      721 attggcgtgg ctagcaatcg gcgcaacatt aggtgaagta agcttcaaaa aagctgcatc
      781 tgaaaaaact tcatggtatt acagtctagt caaagtggta tttgtacctg cattgaatat
      841 cgtgattcta gcagttttga cggcaacgaa tattctacca gtcaattttg aagcactggc
      901 aacaatcgtt atcatgatgg ctacaccagc tgcaacagtg gcagcagcct atgctatcag
      961 ttttgatagg gaggcacttt tagcctccaa tgcatcctta ctgtcaacta tttttgctgt
     1021 ggtactgaca cctgtatgga tcgttgtatt acaaatgatt catggcatag gtttattttc
     1081 ataagaaatg gaggaagaaa gtatgagaat cgcatgttac ggtgttcgtc cgaacgagat
     1141 agattttttt gaaaaattga atatttacca ttatgatctc agtctttatg aagaactgtt
     1201 gacacatgac aatatcgtgt cagcaaagga ccatgatgct gtattgttga ggggaaattg
     1261 tatagcagat gagaccaatc ttgcaaaaat gcaggaatat gggattcgtt atgtttttac
     1321 acggactgtg ggagtcaatc atatcgatct acaagcggca gctgattttg gtatgacagt
     1381 agcccgtgta ccatcgtatt cgccaaatgc gatagcagag ttatctttga cttttgccat
     1441 gatgcttttg agaaatactg cgtatacgac gatccgaaca tctttcaaag attttcgagt
     1501 ggatgagcaa atgtttagtc gtgaaatcag aaattgcaca gtagggatca taggaacagg
     1561 caggataggg ttgacggaag ctgttttgtt taagggacta ggagccaaag tgatcggcta
     1621 cgatattcat cagacagaag ctgctaaaaa agtattgacg ttccactcgc ttgaagagtt
     1681 attagccaaa agcgatattg tcagtattca tgtacctcat atcccaggtg aaaacgatca
     1741 aatgatcaat gaaggatttt tagctcaaat gaaaaaaggt agcatcttga ttaatacagc
     1801 ccgtggagag cttcaagata atgaagctat tttaagagct ttgaaaagca atcatttagc
     1861 tggttttgca accgatgttt ttgcaaatga aacagaggtt tttttccgat ccttcaagcc
     1921 atgggagacg attccagacc ctgctatcca gcaattagta gaaatgtacc ctagagttct
     1981 tgtaaccccg catgtaggtt caaatacaga tgaggcatta tcaaatatga tttcgacaag
     2041 tttcgagaac tttcgtgaaa taatagaaac tggaaaaacg aaaaatgagg tatctcttcc
     2101 taaagcccgt caattaagat aagaaaacat ggatattcgt caataaaatg tttaaaaata
     2161 gtccaagtaa acagttgtta cttctgtata cttggactat tttgtatggg ataattcgat
     2221 gactcaacag taatctgtga gctttttccg cccattcttt gtcaattcat aacaggttag
     2281 cggccggccg atttccaaat atttgattct ttcgttcaat atatcttgtt ctactaaaaa
     2341 attcaaatat ttcttgacgg atatacgtga cagtgagctt ttttgagcca gttcttttgt
     2401 tgaaaaaata gtatcttctt ttagaataaa tgcacttatt ttttttaaag tcagttttga
     2461 cagaccttta ggcaaatcga tgaatgatgg tatttcgtga atgggagtgg tgtggttgaa
     2521 tacttgatcg atcaatttct gatcggcttt ttcagtcgtt tggattgtct gagagaaagc
     2581 aagatacttt tcgatcgcca gctgaaaacg ttgcaaagtg aacggtttga tcaaataatc
     2641 taaggcaccg tagcggatca cattctttat ggtttcgata tcatctgcag cagtgatcaa
     2701 aatcactggg atatcatttc cttgctgtct aagccaagat aaaaaatgga taccactttc
     2761 gccaggcatg tatacatcaa gcagcagcag atctgcgttt ttttgtctga aatatttttt
     2821 tccttcttct acatttctga aactttcgat tacgttcata ttagggatgc tttccacaaa
     2881 agtacgattc aattctgcaa ccattggatc atcttcgatt atcaggacat ttgtcatcat
     2941 tttgatcttc cttttttggt aattctagat agacgattgt accgccattt gtttgtttgg
     3001 aaaattctaa aaatccaccg tggcgtttga cgattgaatg gatgagattc aatccaaacc
     3061 cacgattgat tcccttcgtc gaaaaaccta gcgtaaatat tttttctgag atttcttctg
     3121 atatcccgac accgtcatcg cagacggtca cgatgaatac ttcagcttct gtgtcatagt
     3181 ttaaatgaat ccggacctgt ccgtttcttt catgtttttg tagcacggct tcttttgcat
     3241 tatcaagtaa gttccctaac acttgcaaaa gtgaatggat ggagtcatcc atctccattt
     3301 tagggataaa agaatcgctt tctaacagca tttcaacaga ttgttctttg gcttcgttta
     3361 ttttgcctaa taaaaaaccg gcaattgcag gtactttgat cagacttgag acttggccaa
     3421 tctctttttt ataattttga tttagctgct ggataaaatg ggtgacttct tcatacttct
     3481 tcaaatcaat caaaccagaa atgacatgaa gtttattcat gaattcatgg gtttgagctc
     3541 tcatggagtt tatatattgt ttcgtccccc caagctcctc cattaatttc attacttctg
     3601 atcgatttcg taaagttgcg actgctccta aaaaacggtc attgctaaaa agaggtgtaa
     3661 cgctagaaat agtttctatc ccatttaaat acatggattg agtccgaacg gtcgtttgat
     3721 gctcaatcgt ctctttaaac aaaacgtcat atagattatc actgattttt ttcctacttc
     3781 gaaatccaat agctgctctg tttggtagaa aatgtttttt gcaggtgtat tgatcaagag
     3841 gatagtttta tcagaagaga tggctaagat tccttcatct acttcatttt cgataatcgt
     3901 tttttcactt aactgttctg ctatttcttg tggttcaagt ccaagcagta cttttttcat
     3961 tttttgggca agaaaaacgg cgcctatgat gcctacgcta agtccaataa tcaatgaaaa
     4021 aacaatcatt ttttgtccat ctttgacttg attgtcaatc gtgttgtttg ttaagccaac
     4081 acaaactgca ccaataatct cttgatcata ataaataggg acgaaatagc ggaagccgaa
     4141 ccctaacatt ccttcttttt cagagaaaaa ttcttgtcct ccaatcactt ttttcacatc
     4201 ttcatgactt gagaaaggaa gaccgatgta acttgggtct gcgtgagaat atcgaatgcc
     4261 ttcagggtcc atgacaacga taaaatctaa attcgatgca atcatgattt catttgttat
     4321 tccttgaatc gcatgtgtcg ggtcaccagt ctgcagcttt ttttggatga gtttatcatt
     4381 ggcaacgatt ttagcaatgc tagagatttt atctgacaca ctagatcggt tcatcgaaag
     4441 aataaaattc ctgatcaata tggcagaaac aatcaaagaa acgaatgtgg agaaacaaac
     4501 gacaaggatg atcgtgttct ggagctttaa tggttttttc ttaaaaaaag gaaacatagg
     4561 ctacctcgaa agaatttatt gtgaaaattt taacatgaaa acaaaaattt aacaaattgt
     4621 caacgataaa cacaaccttc ctataaaaaa caccactgag tcggtaaaag aagctataca
     4681 gaattttcaa acattggtat gatagacgta gaaatggaag gaggcgtgta tatgataggg
     4741 ggaatcgcac ttgagacgat ttattggtat acattgctga tttgtgcagg attggcagtc
     4801 ctattgatta tttttggaga tgtattcgat tttgatggcc cgcttgatcc gatgcttatt
     4861 atcccttggt taactttcac aagcttattt ggttttctag gtgagcgttt aacagatcaa
     4921 tcatctttat ttttatttat tgctagtgga ggcatatcga tagtgttggt atttttgctt
     4981 aatttctata tattgatgcc gatgaaacat gccgaatcaa cgatgtcgtc ttctgaaaaa
     5041 actctggaag gacaagtagc tgttgtgatc acaccgatcc ctgtacgagg tatgggagaa
     5101 attcagttga aaagtgttac cggttccatt agtcgtccag cttgttttta cagcccccaa
     5161 gaacagacag ctgagcgggg aacgaaagta ttgatcattg agatcaagga aagaatctgt
     5221 tatgtcatgc cttatgaaag catgataaaa gcttaaagga gcgtgtgtta aatggaaata
     5281 ccagttgttt ttatcgcgat cgcaatcgca gctttgattt tactgatgtt gctgatcgtc
     5341 tttgtagcga agtaccagac agcaaaaccg gatgaagcgt tgatcatcag tggaagttat
     5401 ttaggaagca aaaatgtgca cattgatgaa agcaataaca aaatcaaaat tgtgcgtgga
     5461 ggtggcgcat tcgtcttgcc agtttttcaa cgttcgaatc ggatcagtct attatcgagt
     5521 aaattggacg tctccacccc tgaagtgtat acggaacaag gcgtaccggt gatgtgtgat
     5581 ggtacttcga tcatcaaaat cggttcatct gtagaagaga ttgctacagc agcagaacag
     5641 tttttaggca agacaagaga agaactggaa aatgaagcaa gagaagtatt agaaggacac
     5701 ttgcgctcga ttcttggttc tatgactgta gaagaaatct atcaaaatcg cgataagttc
     5761 agtcaaagcg tacaagaagt cgcttctgta gaccttgcaa aaatggggtt gatcatcgtt
     5821 tctttcacta tcaaagaggt cagagacaaa aacggttatc ttgactcttt agggaaacca
     5881 agaatcgccc aagtcaaaag agatgcagat atagcagaag cggaagctct aaaagaaacg
     5941 cgtatcaaaa aagctcaagc agaaaaagaa tcacaagcag ctgaattaca gcgacaaaca
     6001 gagatcgcag aatcattaaa agaaaaagaa ctgaaattag caacctacaa acaagaacaa
     6061 gatgttgcta aagcaaaagc agaccaagcc tacaatttag aaagtgcccg agcacaacaa
     6121 caagtaatcg aacaggaaat gcagattaaa atcgtagaac gtcaaaaaca aatcgaactg
     6181 gaagaaaaag aaatcacacg tcgtgaaaag caatatgatt cggaagtgaa gaaaaaagca
     6241 gatgccgatc ggtacgctaa agaacaagaa gcacaagctc aaaaagtcaa agaagtgact
     6301 gaagccgaag cagaacgatt ccgtgtggaa gcactggcag aagcggaagc caataagaca
     6361 cgtttagctg gacaagcaga agccgaagca gcactagcaa aaggaaaagc agaagccgaa
     6421 gcaaaacaaa agatcgccaa tgccttcaag gaatatggcg aagcagctgt cttgagtatg
     6481 gttatcgata tgctaccgca attgatgcgc gaagcagcac agccgctagg aaatatcgaa
     6541 aaaatctctg ttgtcgatac aggaagcagt tcaggagaaa ccagtggagc gaaccgagtg
     6601 acaaattatg ccacaaattt gctttcttct actcaagaaa cactaaaagc gacaacagga
     6661 cttgacttga aggaaatcgt agagaatttg tcgacacgtg ggactactag ccaagtaaat
     6721 atgtatgaag cgccaaaaga ggcagaacaa aactcgatga aggaagaata aagtagtaca
     6781 cttcaccgtt caatcaaaaa tggaggaaga ctttttaaag ttcttctctc cattttttta
     6841 ttttattgca aaagaaaatt agtcctcgct atttttcttt tgtttttgga tcttagcttc
     6901 tatctcttgt aaatttgttc ttagcaatcg ttctttcttt tggagttcga ccaaatcttc
     6961 tgatagttct tccttctttt ctgtttcagg aggacgaaga aagaaattga taccgattgc
     7021 aatgaatgtc cctataaaag tatctagtac acgttggata gcatacaaag cggattcgcc
     7081 ttgagggatg ctcaacgcaa tcagcaacaa cgtagctatt gcggaaatga taccggaatt
     7141 attgttaata ccatctgaca cgacgatcac aataataact agaataggaa gcaagatcaa
     7201 ttctaccaaa aaatcattgt gaaaatagct tttgacaaaa aaataaatga tagctaatgt
     7261 accacctaat gtattgccga tgatcctaga ctttccaaaa gaaacggttg tagtcaagtc
     7321 ctgacgcaaa gaaaaaacag cagataatgc agcaatcatc gggattcctc gttgagtcaa
     7381 atgaaaaaac aagatacata aaaaaacagc taaggcactt ttgatcgtac gcatacctag
     7441 tcgaaaacgg ccaaattgca tagagattct cctttttggt ctttttacta tcatacctaa
     7501 acttttgtct gatagctagt ttttcattat tcaagtataa ttaaaataaa aaagggggaa
     7561 gtaaatgcgt ataggaatgc gaacagtcaa aacagtgatc agtgtcttct tttcgatggt
     7621 cacagcgggt agcttatcgc tgttgtattg gccagctgca gggatcattg cattattaag
     7681 tgtaggaaat accaagcgct ctacattgcg tacgggcatg aatcgaatcg cagcctttat
     7741 attagctacg gcaacagcac tgttcagttt ttttgctgtt gggtatacta tttttggctt
     7801 cagtcttttt ttattcctgt tcatcccgct tgcctctcgc ttcaaattaa ccgaagggat
     7861 agtagtaaat tcggttttgg tcactcatta tttagtggag gaaaacatgt cttggcagct
     7921 gatcggcaat gaagcgggat taatggcgat tggattagta tttgctttgc ttgcaaatgt
     7981 ttacatgcca gatcgtacga agcagctgaa ggaaaaccaa atacagatcg aaaaagaatt
     8041 tcgaaatatt ttgagacaaa tggcagaatt tcttttatca gaaaataaag aagatgtgca
     8101 gatcaaatgc gaacatttac tgacattcat tcgcgaaagc caagaagatg ccagagaaca
     8161 tcaagaaaac tactggctca gacagccgct atactacgaa acttacttct ctatgagaag
     8221 agcacaggcc aatgtgatta aagacatgct ggaaaatcta gagagaatcc agcaaccagc
     8281 ttattatgga aaacatatct atggtttatt gatttatact gcagaaacat tttcagagtc
     8341 aaatgatggc agacaaattt taacacgtat tgaagaagtt tatgtattgt atcggcaaat
     8401 gcctctgccg actagtcgcc ctgaattcga ggatcgagca gaattgttcc agtttttgca
     8461 gtcttttaaa agttttattg aaatcaaggc agaattctcc caacaaaaaa tccaaaaata
     8521 gaggttgtga attcagctaa tattcaggtc aaaaagctga tttcacaacc tcttctttaa
     8581 acggtgttct cctgtcaact cctcggtcac aagtcacaat attcaacaaa catgagaagc
     8641 tgttttttga aattgctcct tgtgactcgg agctgaacgg taggctcaca acctctttct
     8701 taaacggtgt tcaaaagctt tcctctgcgg taataagtcc agccaaacga aaaataggag
     8761 gagctatttt tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaaccttt
     8821 taaaattaca tatttttcca tagaacttgc atttgatcca agatttcgat gacatctttt
     8881 gtcaagaaga gagagcgatt gggcaagtca ccttcaatca tgtgtaccat attctttatt
     8941 tcgtaattca ttgcttcaga tgtattcccg ctttcgatga attcctttgt accatctgta
     9001 aataagatct ccgcacgatc agcacgcggg taatcagcaa tcgtcacata accgttctca
     9061 aaggcaacga taccgacttt tggcattttt gcctgaaaag tcaagctgac agcagcaagt
     9121 tcattttctt tgttacgcaa gatagtgacg gattgttcgt ccacgcctgt ttcaaaagga
     9181 accattgtag aggcaactac ttcaggttga gagctcaaaa agaaacgagc gaaagataca
     9241 gcatacgtac cgatatccaa cagagctcct ccagctaatt ctggattgaa gaaccggttt
     9301 ttagggtctg gttctttgta actgccgaaa ggtgcttgga tcatttttaa agcccccagt
     9361 tttcctgtat ccattattga gcgtaactgc tgataaagtg gcatgttgaa gattgtcatc
     9421 gcttctgcta agatcaaatt cttttcttct gctaagcgca tagcgtcagc cagttctttt
     9481 ttattcatcg tgatggcttt ttcacataga acgtgtttgc ctgcttccaa tgctgccaag
     9541 atatggtcga tatgctgtct atttggtaca gcaatgtaca cgatgtcgat ttcagcatcg
     9601 tctaacattt cttgatagct tccgtaagct tttggaatat tgtaacggtg agcgaagttt
     9661 tccgcttttt ctgaagttct ggaagcaact gctgttagtt cgctcgtctc ttgattgaag
     9721 ctttcggcaa actcatgtgc gatggtacca agaccaacga ttccccattg atattttttc
     9781 atctgaaaac gctccttcat agttggattg agtttcttgt ctgtctatta ttataacaaa
     9841 aatcacgaag aataaagagg agaggacttg aaacattaaa aaaaatgaaa gcagcgattt
     9901 aagaggtgct ttttgatcaa aacttaagta gaatagttaa aaggagggga taaacgtgca
     9961 tcaagtatat attgatctta ttatgagtgt attattagaa cagtttgaaa ctgaaaaaaa
    10021 ttttttagat gaatacttgc tgatcagtcc agaacaatgg caaaaatgga aagatggcga
    10081 gaaaaatctg ccatctgaag cgatgcagaa agtaaaaaat cttttcactg attatgaatg
    10141 gatgctaacg caaaagattt tgcgtcaaac gattattttt cccgaaaaac gaaacgttgc
    10201 cgttgcagag tacaagcaaa tcaaaacacg catcgcgcaa aaatggctta gcagcaaagc
    10261 agcaaaagtc gagctgatcc ctttgaaaaa taatcagcag gctggtagat accttgactt
    10321 gaaagtaagt attcaatatg atgaatgggg ctatgatgat attttgaatt ttcgtctgcc
    10381 agcagatgtt caaaaacaga tcgaaggaga aaaaatcgaa cttctcgatt gggtgaatga
    10441 aaatctggaa gaaacttacg ttcatgaggc gaatggggaa cgtgaagaac aacgaaagga
    10501 tttttcaagt gaataaattt ttaggatttg gagcagttgt gattatgatc gcagcaatgg
    10561 gctatgttat ttttagcgat gatgattcgc atgttcaagc cggcaatcaa gcagtcgaac
    10621 gaacaagcac caaaacaact gctagtaaag aaaagaacag tcaaacaacc agcagcaagg
    10681 taaaggacaa agaaacaaaa gatcgtacgt ccaaacaatt gccagatgtt aaaacagacg
    10741 attggaagct agttttggtt ggtccagatc acaaattaga aaaagaaatt gatgagtcta
    10801 ctcaattggc atcattaagt aacggatact tgatcgacaa acgcattgct ccagaatatg
    10861 aagcatttgc caaggctgct gaagcagctg gatttccatt agtgatggtc tcagcttacc
    10921 ggtctgtatc atcccaacaa caagttttcg aacaaaatgt ccaagatgtg atgagtcgtc
    10981 aaggtgtatc agaagaggag gcgacaaaga ttactaaaga aacgattacg gagccaggat
    11041 acagcgaaca ccacacaggt ctggcagtcg atgtcgtcga tcaaaactgg tacaacagtt
    11101 atccttctac tgtattggat gcaagttacg gagatcagcc tggagctaaa tggatcgcag
    11161 ataatgctgc gcagtatgga tttatcgttc gttatccaaa aggacacgaa gatataacta
    11221 agatcacata tgaaccttgg cacttacgtt atgtcggtaa agaaaacgct gagtatatca
    11281 ccaaacacca attgacgcta gaagaatatc tgaatgaatt aaatgaaaag taggaattga
    11341 tcatggcgaa aaaaaagtgg aaaaagcaaa agcgcaagaa tatccgttgg ccagcagtgg
    11401 ttgccggtgt agcagtgata ctcttagcct ttgttttttc cttgaagaat ctgtcttctc
    11461 cttttactga taatcagcaa gaaaatgaag cgcaatccca tcagcaattt attgaacggc
    11521 ttgttccgca tgcccaagaa ctacaagatg gttatggagt gcttcctagt atcattttag
    11581 gacaagctat attagaatca aattggggaa aaagtacctt ggctagcaaa tacaataatc
    11641 ttttcgggat caaggcttat ggggatcaga agaaagtaag cctggaaaca aaggaatttg
    11701 ttaacgaaga atggataact atccaaggag acttcaaagt gtatgattca tgggaacagt
    11761 ccatggatga ccatacacaa ctgttcgtcc aaggagtaga ttggaatcct gcgctgtatg
    11821 aaaaagtgat tacggccacc aactatcagg aagccgcaca agcattgcaa gatgcaggtt
    11881 atgcgacaga ccccggttat gcgcaaaaaa tcatccaggt catcgagacg tatcaattga
    11941 atcagtatga ccggagatag caaaggagaa gtggctgatg gcagaacaat ttacgccaga
    12001 aatcatgacg gaattgagaa aagatatcgt aagagtaccg gaaatcattt tagaagcaag
    12061 cgggatcaag atatttggaa aattgatccg ttcgatcatc tttactacgg atattgcgat
    12121 catacgtaat acaaatgcga atgcagtaat tgctgtgtat ccttttacac ctcatccagc
    12181 gattactaaa agcattattg aggcagctga cattccagtt ttctccggtg taggtggtgg
    12241 tttgacacaa ggtgctcgtt cttcctacat gagcatgttc gcagaagcgc aaggttcgtt
    12301 aggggtcgtt ttgaacggtc ctacgccttt agagacagta aaagaagttt gtcgagtagt
    12361 tgatattcca gttatcagta cggtaacgtc gaaatataca gaaatagatg aaaagttagc
    12421 agctggtatt tcgattatca atatcagtgc aggtaaagaa actgcagaag cagtacgcca
    12481 ttttcgtaaa aaatatcctg aacttcctat cattgcgaca ggtggtccaa cggaagaaag
    12541 tattgctgag accattcaag caggagcaaa tgccatcaca tatacgccac caagtagcgg
    12601 agagcttttt agtcgtaaaa tggaaaaata tcgggaaact gagaaaaaga atcatgaata
    12661 acaggtgaga atcaaaagac gaggaagagc agatagtggc tcttcctcgt cttttgtact
    12721 ccagtactat ttgttcagaa ttcaaaaaaa agagaaattt ttttgttttt ttacctgtaa
    12781 tgtacataag aagagttaaa accttttgtt attattagca ttctaacaaa aaaatgtctt
    12841 gatttattga agcgctttct atagaatgaa aaacgaataa aaactaaaaa aggcacccga
    12901 caatttagta gcagctaaat tgtcggggct tgaaaagtca gcgggaactg accaatcaag
    12961 ttgccatagt caatgcttgt gcatcgacgt gtatattgta cctaatttca tacagaatta
    13021 ctagttattt ttctgttttt tagggaagag cgcacacgaa gaagcatgct tatttagcta
    13081 tgtcaaggat attgggcagt tgtctgatat ccttttttct ttgcgtaatt atcctcccat
    13141 cattgaagca agaagtgttt ttagcgatga aagaagaatc agcactatct aatttttctt
    13201 gaaagtattg agttgttcat cctaggcaga acgataaggc aagtcttggt ttttattccc
    13261 cttgaaaaag atcgtttaat aaatatgttc tgtataaaaa tacagtatat tgaaaaataa
    13321 caatggaagt agaggtgcag agaatgaaga aaagaatgag aatcatctta gctttaagtg
    13381 ttatgttatt cttcttgacg gcttgtgggc aagaagatga caaaaaaatc acgctgaaca
    13441 tggcttggtg gggttcgcaa gtccgacacg atgcaacagt aaaagtaatc gagctttatg
    13501 aagaaaaaaa tccccatgtg acgatcgatt atgaatttta tgattatgaa ggatattaca
    13561 caaaattagg tacactagca gcatcagatg atatctggga cattttccaa ctgaacaatc
    13621 aatttcctca atacatcaat cagattgaac cattagatga atatgtggag caagggataa
    13681 ttgatatttc taatgcagat gaatcctatt tagcaacgac gacttacgac gggcaattag
    13741 ttggactgtc taacggggtg aattcgtttg cgattgctta caataaaaat atatttgaac
    13801 aattaaatat ccctgaacca gcttcaaatt ggacatggga tgaatttgaa caaatcagct
    13861 atcaaatcac tgaagaatta ggaatctatg ctatttcaag attcgaagat tttatagctg
    13921 gctgtattat tcaaatacca caagttgaga aaggattgaa tttttataat cgggaagatc
    13981 tatctaacag cttgggattt gaaaatccag actatctaac agattttttc cagctgcgta
    14041 aaaatctggt agacaaaggg gcccatccag aaccaggtgg tggagctgca agtacgacgg
    14101 atctgtcttt tcaggcggtt agggatagag aagcggcaat ggtgtttcta tcaagtaacc
    14161 agttgacaga aatattgtca ggggctcctg aagatatgga gattcagttg attaatccac
    14221 ctcgcagaaa agcagatgga gaatctggta tccctttacg ttcttcgcaa atgctgagta
    14281 tggcaaaaag ctcagcccat aaagaagaag ctgctaagtt tattgatttc tttcaaaaca
    14341 gtgaagaagc caatgaaatt ttaaaaggag aacgtggtgt accaatcatg tcgaatattc
    14401 gagaacagct cgctcgtgca gatgatgcaa ctttgcaagc gacatttgat tatttagaaa
    14461 tgatttccga tatggacaac ggcgaagtga atgtctttga tagtgctttg aatccggaaa
    14521 ttcaagacca atacaatctt ttagttgaaa aagtcattta tgaagaagta acagcagaag
    14581 aagcagcaga gagtctttat gagtttgcgt caaacattct aggatagcag caggaggaag
    14641 gcatgaaaaa agaaaaacta aaacggttct tggatcaaga caatgtggtc ggttacgtat
    14701 ttgcttctcc attcatccta ggatttctat tgataacagt gataccgatg atcttgtcac
    14761 tttattattc gttcaccgat tatcgtttgg gaaatccagt ctcatggatc ggcttggata
    14821 attatataaa gatgctgagt gatgcccgtt ttttgaactc catccgagtc acttttctct
    14881 atgtatttgc atctgtacct gtgaaactga tctttggtct attgattgct tatcttttaa
    14941 cgaggaatat caaaggaacg actttctttc gttctttgta ttatgtgcct agtttgatcg
    15001 gtggcagtat ttctatcgct ctagtttggc gggagttgtt ttctaaaaac gggttagtga
    15061 atattttcct ggaacgatta ggcgcacctg cgctttcctg gtttagcgat caaaaactgg
    15121 tcatgatccc tcttgttttg atgtctgctt ggcaattcgg ttcggcaatg atcatctttg
    15181 ctgcaggtat caaagagatc ccaggctcgt attatgaagc ggcagagatc gatggagcga
    15241 acaaatggca gacgttttac aagatcacgt tacctcttct ttcgccgatc attttgtata
    15301 acttggttat gcagacaatc gcggcgttta tgacttttac gcaggcattt atcattaccc
    15361 aaggtggtcc gaatgatgcc acgaactttt atgctcttta tgtgtataac caagcttttt
    15421 cttttaattc tatggggtat gctagtgcta tttcgtggat catgctgttg attatgggag
    15481 ctgtcacctt tctgattttc aaatcatcaa aaaaatgggt cgttgtgtga atgagaggag
    15541 gaagaaatga ataatacagt aacgaaatgg tttcaatacg gttttatttt gctattaggt
    15601 ctagtcatga tttatccggt cttatggatg atcgcaggtt cttttaaaac ggatcaagag
    15661 attatgagtg gttcgctgaa tttgattcca gagacttttc aatgggaaaa ttacgcaaaa
    15721 ggatgggcgg ggtttgctgg aatttcattt tttactttct ttaggaattc gtttgtcatc
    15781 tctgcagttt cgacgatagg gacagttctg agctcgactt gtattgctta cgcattatcg
    15841 agaatcgatt tcaaaggaaa aagattctgg ttcgtcgtca tgttagtaac gatgatgatt
    15901 cctgcacaag tgattttgat tccgcagttt attatttaca atcggctgaa tttggttggg
    15961 acgtatgtgc cgctgatttt accacatttt tttggacaag catttttcat ttaccagatc
    16021 atgcaattca tggtcagcat ccccaaagag ttagatgaat cagcgattat tgacggatgc
    16081 agcaagtata gtgtctttac caaaattatt tttcctttgc tgaaaccttc gatcatcacg
    16141 acgatcatca tccagtttta ttggaaatgg gacgacttca tgggaccatt gatttattta
    16201 aacaagccga gatcttacac ggtatcgatt gccatcaaat tatttgcaga cgctggatct
    16261 agtacgactt acgcgagtat gtttgcgatg tctacgttgt cgctgctacc ggtttttctg
    16321 attttcttat tcttcaataa atatcttgtc caggggatca gtacaagcgg tctgaagggc
    16381 tgaatatgaa aaagccaata gaagagatgt ttctttacaa gctcaactac tatgtctgtc
    16441 ggattttttt aaccagtctt atcagtaatg ctcttttcgc tttagttcta ggatgtttgt
    16501 tcactttagg attagtgctg tctgctcgtg ttgtctatct gatttatttt ttgatgatgt
    16561 atccttctta ttatctatct gtccattact tggcagaaaa aaaggtatgt tggaggaaag
    16621 gaaaaatcaa acggatgtgt ttcatcatta cgttgtttca gctgtttgtc attatttttg
    16681 cagttgattg gtatttatta gtgggaaaga ttggagcttg gtatctgatt ccttttctat
    16741 tgtgtctgtt gctttttgta tcccatagtt tttttagtac gctaattgat atctgcaaag
    16801 aagataaagc agatagtctt gtttatttga tcaaaaggaa tatctggctg ttgtcaaaaa
    16861 acgtcaaggg gtttctgtgg tatttatgcc ttttgtatgg actgttctgg tgtatacagc
    16921 atgatttttt actcactgca ttactgtatc cagggctgcc atttgtcaca gtattttgct
    16981 taaaagaaaa ggagaatgac tttaaatgaa gaaaaaatat gtacaagtcg gacttggtgg
    17041 gagagcgcgt tttttttatg aggcaattgc ctctacgtat catcaaactt gtgaactagt
    17101 cggtttttgt gatgtatctc aaacaaggat ggattatgca aatcggatac ttgtgaacaa
    17161 gtatggacag aaaaaagtaa agacatgtat gccatcacaa tttgagcaac tactggatga
    17221 cgtacggccg gctgaagtca ttattacgtc agtagatcga acgcatcatg attatatcat
    17281 tcgtgcaatg aaaaaaggat atgatgttat ttgcgaaaaa cctctgacta tcgatgagga
    17341 aaaagctcaa gaaataataa cggtccaaaa acagacggga agaagcctgc gagtcacttt
    17401 taattatcgt tatgcaccgt atcacacgaa gataaaggaa ctgatagaaa gtgatgtgat
    17461 tggtgatgtg ttttctatcc acttcgaatg gctgttaaat acgcaacacg gggcagatta
    17521 tttcagaaga tggcatcgaa ataagcacaa tagcggcggg cttcttgttc ataaatctac
    17581 ccatcatttt gatctagtga atttttggtt gaacagccgt ccccaaaagg tatttgcatt
    17641 cggtggatta aacttttatg ggatgcataa tgcggagaaa cgcggagtag aaatatttta
    17701 cagtcgatgc tatggaagcg aactagctaa agctgatcca tttgctatag acctgtcagc
    17761 caatgaggaa ttgcgagaaa tgtatttaga agcagaaaaa gacagtggat atattcgtga
    17821 ccgcagtgta ttttccgatg atatctctat tgaagataca ctaggcgtaa cggtcaaata
    17881 tgaaactggt gcgattttga cgtattcgct aaacgcgtat atgccgtggg aaggattcaa
    17941 tgtttctttc aatggcagca aaggacggat cgaaatgaaa gtgatcgaaa agtcttacat
    18001 caatgcaggt ggagataaaa aggatgaagg agcagccgtt cttcagtcca tccatgtcta
    18061 tccgatgttc ggtgagccat atgaggtaat cgtcgaacaa gaagcgggcg gacatggcgg
    18121 aggagatccg cgtttattag atgatctatt tggtgaagaa aaagaagaag atccgtggaa
    18181 tcgggcagca actcacgtag atggtatttt gtcgattttg acaggaatcg cagcaaatca
    18241 ttctattgct tcaggaaaag cagtagtgat tgacgagctt gtcagcttaa aagaataaga
    18301 atagatttac ggaaattact tcccgtagtt tataaaatct tgccttattg ccgataggct
    18361 gtcttttgaa cactatttat tcggaaaaag gggctatgac atgctttttg tcatgccttc
    18421 tttttatgtg ggctgctttt ttagatagga gaaaataaaa ataactattt aaacccgaac
    18481 aaaaaggaat aatgcattaa aaatcattag attttacaaa aaaataagta aaccacgttg
    18541 tcagtttcag aaagtagtgt tagactgttt tcaatatttg aaacaacatt ttttattcaa
    18601 atatggcaaa ctgccttcac gtgcaaaaca gttgcaagaa aatgaattta cactattatt
    18661 agttttacat acctacttat atatcgtcat aatatggatg acagtttcta gccagtaccg
    18721 taaatgctgg actataagta aaagattggc tatttcaccc ttcttttctt atgataaagt
    18781 ggagggtgtt tttctttaac agaaacatag taggtttttg cacaaaagcg gttatttcgg
    18841 tattaataaa tgataaagga gcaaataaag tgaaagaatt agttgaacgt attcaaaaag
    18901 acggacgtat attaggcgag ggcgtattaa aagtcgacag cttcgtcact caccaagtag
    18961 accctgtatt gatggaacaa atgggaaaac ggtttgcaga agtatttaaa gaacaaggaa
    19021 tcacgaaagt tgtgaccatt gaagcttctg ggatcgcacc agctttattt gctgcaagag
    19081 aattagatgt tccaatgatc ttcgctagaa aagcaaaaag tttgacgatg gatgaagaat
    19141 tattgacagc ttctgtttat tcttttacga aacaagtgac aagtacgatt tctatttctc
    19201 gtaaattttt atcttcagaa gacaaagtat tgattatcga cgatttcttg gcaaacggac
    19261 aagcggcaaa aggattgatc gaattatgcc agcaagctgg agcgcaagta gaaggaatcg
    19321 ggatcgtcat cgaaaagtct ttccaagatg gacgtcagtt acttgaagaa atgggattga
    19381 gagtcgtttc tcttgcgcgt attgcttcct tgacgaatgg acaagttgag tttcttgagg
    19441 aggacgcata atcgtggaaa aagaaacaca aaatggaaaa gctgcggttt tagggctgca
    19501 gcatctgcta gcgatgtatg caggagcagt agcggtgcct cttttgatcg gtacaggact
    19561 aggctttaat caagaacaga tgacttattt gatttcaatt gatatcttta tgtgtggatt
    19621 agcgacatta ttgcaattga cagttaaccg atttttcgga attggcttgc ctgtcgtttt
    19681 aggatgtgcg atccaagcag tagctccact gatcttgatc ggaaccaatg aaggagtagg
    19741 agctatctac ggatctatta tcgcttctgg gatctttgtt gtgttagttt ctggtgtctt
    19801 ttctaaaatt aaaaaactat tccctcctat agtaacagga acggttatca ccgttattgg
    19861 tttgactttg attcctgtag caatcgagaa aatgggtgga ggtaatgcaa cagcagctga
    19921 ttttggtgac aaaacaaatc tgctacttgc atttgtgacg attctcctaa ttgtaggcgt
    19981 gcaaatgctg gcaaaagggt tcattcgttc aatcgcggta ttgattggtt tagtcggagg
    20041 aagcatctta gctgctttca tgggaatgat tgatctgagc gcgattggag atgcgccgtt
    20101 gttccatgtt ccacaaccct tttattttgg taaaccaact ttcgacgtat ggtcgatttt
    20161 actaatgatc atcatttcca tggtcagcat ggtagaatca acaggtgtat attttgcact
    20221 tggtgacatt actgggaaaa atgttggaga agaagaattg aaaaagggat atcgtgcaga
    20281 aggacttgcc gttatcttag gcggtatttt caatacattc ccttatactg gcttttctca
    20341 aaatgtcgga ttggttcaac tttcgggaat caaaacaaga aaacccatct atttctctgc
    20401 attcttcttg attgttttag gattattccc taaaatcggt gcgttagcac aaatcatccc
    20461 tgagccggta cttggtggag gaatgttagt catgttcggg atggtggcag tccaaggaat
    20521 ccgtatgctg ttggaagttg atttcagcaa tgataaaaat ctattgattg ttgctgtttc
    20581 tgttggattt gggctgggtt tcaatgttac gccgacatta ttcagtcaaa tgccgcaaac
    20641 attgcaaatg ttcactggaa atggcatcgt aatgagtagc attacggcta tcatattgaa
    20701 tttgatcttt aatggattga aaaaagatga agaaatattg gaagaagcct tcaagaagta
    20761 atagagcaaa agaaaggttg tgaaatcagc gttttgacct gattgttaga gaaacaaacg
    20821 gaaaaatagt tcctcgtatt ttgccgtttg tttgagctaa taccgagggt cagctgattg
    20881 aacaccgttg aaggaagagg tcgtgagcct gccgttcatc tccgagtcac aaggaacaat
    20941 ttcaaaaaaa agcttctcat gtttgttgaa tattgttcct tgtgaccgag gagttggcag
    21001 gagaacaccg tttatccata aaaaggaatg tgacctaact tttgtcacat tccttttttt
    21061 tatctttaat aaacacgaac aataaaatgt ttttctttgt taacattcga aatttctttg
    21121 acatcaaaaa aagtgattgt taaaatatga atgtagaaaa actgggagga aaaacaatga
    21181 cagcaaaaat ctctgtgatt atggggagta cttcagattg ggaaacaatg aaagaagcat
    21241 gtcaaatatt ggatgaattc ggtgtgtctt atgaaaaaaa ggtcgtttct gctcatcgaa
    21301 ccccagattt gatgtttgaa tatgcacaaa acgctcgaaa aaaaggaatc aaaatcatta
    21361 ttgcaggagc agggggagcc gcgcatctgc cgggtatggt cgcatcaaaa acaactttgc
    21421 cggttatcgg tgtaccggtc caatcacgaa cattaaatgg tttggattcg cttctttcga
    21481 ttgtccaaat gcctggagga gtacctgtag ctactacagc aatcggaaaa gcgggagcaa
    21541 ttaatgctgg actacttgcg atacagatgc tttccatgta tgatttagaa ttggaggcta
    21601 aattggctga aagacgttca atgttggcta aaactgttat agaaagtagt gatcaacttg
    21661 gttaaacctt tgttgcctgg ttcaacgatc gggatcgtcg gtggcggtca attaggtcgt
    21721 atgatggcga ttagtgcaaa agaaatgggc tttaaagtag gtgtgctgga tcctgtgagc
    21781 gattgtccag ccgcacaagt tgcagattgg cacattgaaa gtgtctatga tgacaccttt
    21841 gcgctgaaag agcttgccag aagaacagat gtcattacct atgaattcga aaacgtcagt
    21901 gtagaggcgt taaatgcgat tttacccatg tcatttattc ctcaagggac agacttgctt
    21961 gcgattacgc aagaccgcct gttagaaaaa tcttttttgg aaacgaataa catcgtgatt
    22021 gctccttatg caacgatcgt cagtccgacg gatatccaag atgcgattga cgggatcggc
    22081 tatccttgtg ttttgaaaac cactcgaggc ggctatgatg gcaaggggca gtatgttttg
    22141 aaaagtcggg cggatctagc tcctgccatg gaccttttaa gagaaggaac ctgtgtttta
    22201 gaagcatgga tcccgtttga aaaagagatt tcgatcatgg tggcaggaaa tggtcaagga
    22261 gatttcacga cttttccggt cgtggaaaac atccaccaca acaatattct tcatgaaacg
    22321 attgctccag ccgcgattga tcaggatgtg atcgaggagg ctgagcgtat tgcccgtgtg
    22381 attgcagaag cagtgagcct ttcaggtgtt ttaggggtag aaatgttttt aacaaaaaca
    22441 ggcgggctat atgtgaatga attagctcct cgtcctcaca attctggaca ttattctatt
    22501 gaagcttgtt ctatgagtca gttcgatgcc catattcgag gtatttgtgg ttggccatta
    22561 ggagaaaaag tacgtttgat aagcaatgca gtaatggtca atgttttggg agaacaactg
    22621 ctggaaagct atcgcttgat tgagaataag ccagactggc aattccattt ctatggaaaa
    22681 aaacaagcaa aaaaaggtcg caagatggga catatcacta tcttgacaga agacatccag
    22741 caaacgctgg aagaaatcaa acaaacgaat atttgggatt agaggagaaa aaacatgtta
    22801 gaacgttata cacgccctga aatggggaat atctggacgg aagagaacaa ataccgtgcg
    22861 tggctcgaag tcgagatttt agcagatgaa gcttgggcag aacttggtga aatcccgcaa
    22921 gaagatgtga aaaaaattcg tgagcatgca tcatttgata tcgatcggat cttggaaatc
    22981 gaaaaattaa cacgccatga tgtcgttgcg tttacacgag cggtttctga aacattggga
    23041 gaagaaagaa aatgggtcca ttatggtcta acaagtacgg atgtcgtaga tactgcttat
    23101 ggctatctca tcaagcaagc aaatgatatt ttacgggaag acttgaaacg ttttacggaa
    23161 atcattggcg aaaaagcaaa agaacacaaa tatacagtga tgatgggtcg gacacacggt
    23221 gtccatgctg aaccaactac ttttggattg aaacttgcca catggtattc agaaatgaaa
    23281 cggaacatcg aacgatttga acatgcggca aaaggagtag aagcaggaaa aatctcagga
    23341 gcagtgggaa cgttcgcaaa tatcccgcca tttattgaag agtatgtatg taaacaattg
    23401 gggatccgtc cacaagaaat ttctactcaa gttctccctc gggatctaca tgctgaatat
    23461 ttctcagcga tggcgcttat tgctacaagt attgaacgtt ttgcaacaga gatacgcgga
    23521 ttgcaaaaat ccgaaacacg tgaagtagaa gaattttttg cgaaaggtca aaaaggttct
    23581 tctgctatgc cgcacaaaag gaatccgatc ggttcagaaa atatggctgg tctagccaga
    23641 gtggtgcgcg gacacatggt cactgcctat gaaaatgtca cattatggca tgaaagagat
    23701 atttctcatt cttcagcaga acgaatcatc ttgcctgata ccacgatttt attgaattac
    23761 atgttaaatc gttttggcaa tatcgttaaa aatctaacgg tctttcctga aaacatgaag
    23821 cggaatatgt ctgcaacatt tggtttgatt tatagccagc gcgttatgct gaaattgatc
    23881 gataagggaa tgacaagaga agaagcttat gatcttgttc agccaaaaac tgcgtacgct
    23941 tgggacaacc aagtgcagtt ccgcccgctg ttagaagaag atccaaccat cacatcggta
    24001 ttatctaaag aagaaataga cgatgccttt gattatcatc atcatttgaa aaacgttgac
    24061 gtgatattca aacgagtagg tttggaataa agaagagtga gttgcaaaat tcaattaaaa
    24121 tagaatagca aaaataacca aaaaagaagc agatccgtta gcggttctgc ttcttttagt
    24181 ttattatatt ttcttatcaa taataggaac ctgattttaa aagcggctac ctctttaccg
    24241 tgcctcttta catacaaaaa atagaggaat taagcgtaaa tggcttggct attataacta
    24301 aaatgctggt tatggagatg ttgcagcaag ttttcgagaa aagcgtattc catctcttgt
    24361 ccattgaata agatctggat acgataatga tttttgaaac gcttctgttc atgaatctga
    24421 ctgattgaaa gttcgccttt gtgttctgtc tgataaagaa aagtcctttt acggcattca
    24481 gcacagcgct tggttgctcg gcggattttt cggaatgtat aaaaactagt atctttattg
    24541 cataaataaa cgtctttgat cgacagcaaa tcattatata gacaggaacg ttcttcagct
    24601 gttaattctg ataaaaaaag ctgaccttgt tttattgcat cttccatcgg caagtgcctc
    24661 ctcgaaccca ttatccaaat ttttagttaa ttctaatata ccatcattaa gtataaatgt
    24721 aaacgcttgt tgatggtata agattttcgt ttctgataaa acacgaacat taaaagaatc
    24781 taatgcctta aatgtacata tttttgttga tttataaaaa gatgattgct aaaatttaaa
    24841 gtgaaaaaac gaacaaaaaa cgatgtattt gcttttaatg taaataaaaa ggagagacgt
    24901 acatggagaa gaaagaactt ttgtatgaag gaaaagccaa aaaaatatat cttacttctg
    24961 atgagaactt gatttggata gaatatttag atcaagcaac tgcgttgaat ggcgcgagga
    25021 aagaccagat aagtggaaaa ggagaattga ataatcaaat cacaagtgca attttccgtt
    25081 atctgactca aagaggaata aaaaatcatt ttattgaaca attgtctaaa accgaacaat
    25141 tagcaaaaaa agtacaaatt atccctctgg aagtggttat ccgaaatatt gcagcaggaa
    25201 gtttctcaaa acgtctaggt gttcccgaag gtaaagaatt catcaaacca atcattgaat
    25261 tctactataa ggatgaccag ttggatgatc catttatcaa tgaagagcat atctatttct
    25321 tacaacttgc aaagccggaa gaaatcagtg agctgaaagc ccaagcgttg gctattaatg
    25381 aaattttgac cgaattattt gctaaggtcg gtttggtttt agtagatttc aagctagaat
    25441 ttggccggtc gaatggacaa attttgcttg cggatgaagt aacaccggat acttgccgat
    25501 tatgggatga acgtacgaat gaacatatgg acaaagacgt ttaccgcaga gatctaggtg
    25561 atttgatccc agtctatcaa gaagtatata accgtctatc ggaactaact gaagaaaagg
    25621 agcgagtatg atgtatttcg taaaagtata tgtaacctat aaagattcag tgttagatcc
    25681 tcaaggggag gcagtaaaaa aagcagtcca tcgtatggga tatgaaacaa tcgaagatat
    25741 ccgaatagga aaatactttg agatacaact tgctgatgca gaagaaccaa tcgatacagt
    25801 gattgaaacg atttgtgaca agctgcttgc aaatgtaaat atggaaacat accgatatga
    25861 aatcaaaaaa atggaggaag tataacatga aatttgcggt catcgttttt ccaggttcaa
    25921 attgtgacgc agatatgtta tgggcagttc gcgagatcat gggcgctgat gccgaatttg
    25981 tacggcatga tgagtcctct ttagaaggat ttgatggggt tttactgccg ggaggattct
    26041 cctatggtga ctatttgaga tgcggtgcga ttgctcggtt ttctacaatc atggaagaag
    26101 tgattcgttt tgctgaagaa gggaaaccag tattcggtac atgcaatgga ttccagatat
    26161 tgacagaagc aggacttttg ccaggtgtac tgagacgaaa tgagtctttg cattttattt
    26221 gcaaaactgt accattgaaa gtcaacccca agacggcctt tacttcagag tatgaagccg
    26281 acgaaataat ctatcttcca gttgctcatg gggaaggaaa ttatttctgt gacgaagaaa
    26341 cacttcaaga actaaaaaaa aataatcaga ttgcctttac ttataatgac aacatcaacg
    26401 gcagcgtgga aaacattgca gggattacga acaaagcagg gaatgtgtta ggaatgatgc
    26461 ctcatccaga acgtgcagta gaagacttgc taggatcaga agatgggaaa cggttctttg
    26521 cttccatttt aaaaaacttc ggaaaggtga ccgtatagat gaaaacattg aaagaaccga
    26581 cagctgaaga gatcaagaaa aaaagaatct atgccgaatg gggattgact gatgaagaat
    26641 atcgaatgat cgaagaagat atcttaggaa gaatgcctaa ttatacggaa actggactgt
    26701 tttctgttat gtggagcgaa cattgttcct ataaaaattc taaaccggtt ctacgcaaat
    26761 ttcctactag tggacctcat gtgttgcaag gccctggaga aggcgcaggc atcgtcgaca
    26821 tcggtgatgg actagcagtt gtcttcaaag cagaaagtca caatcatcct tcagccgtgg
    26881 agccttatga aggagctgcg acaggagttg gcggaatcat cagagatatt ttcagcatgg
    26941 gggctcgtcc aattgcgttg ctagattcat tgaggttcgg cgaattagat aatccaagaa
    27001 cgaaatattt actagaagaa gtagttgcag gtatcggcgg atacggcaat tgtatcggca
    27061 taccgactgt aggcggcgaa attgcatttg atccttgtta tgaaggaaac ccattagtca
    27121 atgcaatgtg cgtaggtttg attgaacaca aacatatcca gaaagggcaa gccgctggcg
    27181 tcggtaattc gatcatgtat gtaggtgcaa aaacaggtcg cgacggtatc cacggagcaa
    27241 cttttgcctc agaagaattt aatcaagaag aagaacagca acgttctgct gtacaagtag
    27301 gcgatccttt tatggaaaag ctgctgcttg aagcgtgttt ggaattaatc ttgcatcatt
    27361 cggattctct aataggtata caggatatgg gagcagcagg acttgtttca tctagtgcgg
    27421 aaatggcttc aaaagctggc tcaggactta tattgacatt agatgaagtc ccacaaagag
    27481 aaactgggat gacaccttat gaaatgatgt tatcggaatc acaagaacgg atgttgattt
    27541 gtgttaaatc aggagaggaa gaaaaaatcc aagaactatt tcagaagtat gatctagatg
    27601 cagtcactat cggtaaagta acagacgacg ggcaatatcg gctatatcat caaggagaag
    27661 aagtagcaaa tctgccagtc gatgcattag ctgaagatgc accagtttat cataaagaaa
    27721 tgaaagaacc agctcgaatc gtagaatttc agcagttagc tccttatcag ccagttatcg
    27781 aagaacctgg acaagtattg cttgatctgc tgcagcaacc gacgattgct tcaaaacgtt
    27841 caatctacga aacttatgat tcacaagtac aaaccaatac agttgtccgt ccaggaagcg
    27901 atgctgctgt gatgagggtt agagggacga ataaagcgtt agctatgacc acagactgca
    27961 acgcgcgcta tctgtatttg gatccaaaaa tcggaggaca aatagcagtg gcagaagctg
    28021 ctagaaatat tattgctagc ggtggtaagc ccttggcgat caccgactgc ctgaactatg
    28081 gttctcctga taaaccagaa gttttttggg aattatcgac ttcagctgac ggaattgctg
    28141 ctgcgtgtga aacgttagga actcctgtta tttcaggaaa tgtctcttta tataatgaaa
    28201 cggatggtca agcaatctat ccaacaccaa tgattggtat ggtcggattg attgaggatc
    28261 ataaacatat cactactcag gaattcaaaa aatcagggga tctaatctat atattaggta
    28321 agacgtttgc agattttgat ggcagtgaat tacaaaagat gcagcttgga agaatcgaag
    28381 gtgtgatccg aaactttgat ctatccattg aaaagagaaa ccaagagtta gtattgacag
    28441 ccatccaaaa cggattgatt gaaagtgctc atgactgttc agaaggtggc ttggcaattg
    28501 cactggcaga atcagctttc aaacatcagc tagggatatc tgtacagttt gaattgtcct
    28561 ctgctcaatt atttgcagaa actcaatcaa gatttgtgtt gacagtcgca ccggaaaata
    28621 agacacgatt cgaagaaatg atgggagatg ctgctgtttt agcaggtaag gtgacggatg
    28681 aagcgataat cgaaatttca gcaactgacg gtcagatcaa aatagaaact gcagtagcaa
    28741 gaaagtgctg ggaggatgca atcgtatgtc ttatgaagtg aagagtttaa atgaagaatg
    28801 cgggatcttc ggtgtttggg gtcatccaga cgccgctagt gtggcatact tcgggctcca
    28861 tagtcttcag catcgaggac aagaaggtgc aggtatcgtg tccaatgatc gaggaaagct
    28921 taaggggcat cgagatttgg ggctgctttc tgaggtattc aaagatcaaa gaaaattgca
    28981 gcagttaaca ggagaagctg caatcggaca tgtacgttat gcaacagcag gcaatggaag
    29041 tgtggacaat attcagcctt ttctattcaa atttcatgat cagtcgatcg gcttagcgca
    29101 taatggtaac ttgatcaatg ctcgttccct tagaaaagag ttagaggaaa atggggcgat
    29161 cttccattct aactccgata cggagatatt gatgcatttg atccgacgaa gtgaagaaac
    29221 agatttttta aataaattaa aaagtgcttt gaatgaagtc aaaggtggct ttgcctattt
    29281 attaatgaca gaaacggcaa tgattgccgc tttggaccca aatggttttc gtccattagc
    29341 aatcggacaa atgaaaaacg gagcatacgt gattgcctcg gaaacttgtg cattagaagt
    29401 tattggggca cgttttataa gagatgtcca gcctggtgag atagtgatca tcaatgacga
    29461 aggaatccag attgattgct ttacgaagga cacgcagctt tctatttgtt cgatggaata
    29521 tatctatttt gccagaccag attcaaacat cgcagggatc aatgtgcata ctgcacggaa
    29581 aaatatggga cggaatttag cgaaagaatc gccagtaaaa gcagatatgg tcgttggcgt
    29641 acctaattct tctttgtcag ccgcaagcgg ttatgcggaa gctagtggaa tcccttatga
    29701 aatcggatta gtaaaaaatc aatacattgc ccgaacattt atccagccaa cgcctgagct
    29761 aagagagcaa ggtgttcgaa tgaaattatc tgctgtacga ggagtagtgg aaggtaaaaa
    29821 ggtgattatg gtcgatgatt caattgttcg gggtacgaca agcagacgga tcgtccatct
    29881 tttgaaagaa gcaggggcaa aagaagtcca tgtgaggatt gcttctcctc ctttgaaata
    29941 tccatgtttt tacgggattg atattcaaac gcgtaaagaa ctcattgcgg caaatcacac
    30001 gattgatgaa atcaaagaat gtatcggtgc agattcttta ggttttttaa gtgaagaggg
    30061 tctgatcgaa tcgatcggtc tggaaaaaga tgctccgtat tcaggattgt gtatggctta
    30121 tttcaacgga gattatccga cgccgttata tgactatgaa gaaaaatatc aggaatcact
    30181 aaaagaaaaa gtatcgttct tttaaaagca gaccaagaag ggagtatatg aattcaatgg
    30241 caaatgcata cgcaaaagct ggcgtagatg tcgaagctgg atatgaagta gtagaacgga
    30301 tcaagaagca tgtcaaaaaa acggaacgtt taggtatgat gggcgctata ggaggattcg
    30361 gcggttgttt tgatttatcg gtctttcaat taaaagagcc agtccttgtc tcggggaccg
    30421 atggcgtggg gacgaaatta gcagtggcaa tcgaagcaga caaacacgat acaatcggga
    30481 tcgactgcgt agcgatgtgt gtcaatgata tcttagcaca aggcgcagag ccgttatatt
    30541 tcttagacta cttagcaacg gggaaaaatg atccgttacg tttggaaaat gtagtaaaag
    30601 gtgtagcaga tggatgtgtt caaggaaata tggcgctgat tggcggagaa acagctgaaa
    30661 tgcctggtat gtactcaggt aatgattatg atctagccgg atttgctgta gggatagctg
    30721 aaaaatctca attattgaca ggagaaacga tcaacccagg agatgtgttg cttggaatag
    30781 catctagcgg gattcattca aatgggtact ctcttgttcg caaaattttc tttgagcagc
    30841 agcagttttc tttatcatca aaactgccag aattgaaaaa aacacttggc gaagaattgc
    30901 ttgagccaac gaaaatctat gtttcttcct tgcttccgct gatcaaagaa aagaaaataa
    30961 aaggagctgc acatatcact ggtggagggt ttgtagaaaa tatcccgcga atgttaccag
    31021 aatctatggc tgcacaaatc aaacttggct catggccgat tcttccaata ttcggctgtt
    31081 tacaaaaata tggtgaaatt cctgagatgg agatgtatga aatcttcaat atgggcatcg
    31141 gtatggtcct ggcagtcgaa gaatcgaaag taaaagaaat agtacacgaa attgagcaag
    31201 ctggcgaaaa agtttatgaa atcgggaaag tgatcgccaa agaaaaacat cgtgtggtgt
    31261 ttataggaga agaacgatga gaatcgctgt ttttgcttct ggaaacggaa gcaactttca
    31321 agcgctagcc gattatctat cgaaaaaagg attggaatct tcgattgact ggttgttttg
    31381 tgatcagcct gaagcatatg ttttgaaacg tgcaactgcg ttgagtgtac cggcagattg
    31441 tttttcacct aaagaatttg attcaaaaaa agagtatgaa gaagcaattt tgcataaatt
    31501 gaaagaaaaa aagatcgatt tgatcgtatt agctggatat atgcgaatca ttggaccggt
    31561 attgctgaaa aattatgata aaagaatcat caatatccat ccgtctcttt tacctgcctt
    31621 ccctggtttg catggcatac gtgatgcctt tgaagctgga gtaaaagaaa cgggtgtcac
    31681 aattcattat atcgaccaag gtgtagatac tggaccaatc atccggcagg aaaaagtgag
    31741 aattgaacag gaggacacgt tcgattcttt agaagaaaaa atccatagag tagagcatcg
    31801 aatctatcca gaagtgatta gtgaaattat tgaaaatgga ggctatctga aatgacaaga
    31861 gcattgatca gtgtatcaga taaaactggg attgtagcat tcgcccaagg tttgattgaa
    31921 caaggagtag aaatcatttc aacaggagga acaaagcatg cgttggataa agctgggatc
    31981 aaaacgcttt cgatcgaaga agtgacaggg tttcctgaaa tgatggatgg ccgtgtcaaa
    32041 acacttcatc ctaaaatcca tggtggtctt ttaggaagac gcgatctccc tagccatatg
    32101 gaggcaatgg aaacggaaaa tatccaacca atcgactttg tttgtgtcaa tttatatcct
    32161 ttcaaagaaa cgattatgaa accagatgtc gaaatagcag aagctattga aaacattgat
    32221 atcggtggtc ctagtatgct ccgtagtgca gcaaaaaacc atgaatttgt cacctctgtt
    32281 gttgatccat ctgactatga agaagtactt tcagaattac gtcagtatgg gcatacttca
    32341 ctttctttca gacaaaaact agcggcaaaa gtctttcgtc atactgcggc atatgatgca
    32401 ctgatcgctc aatacttaac ggattgggtg gaagaaaaag aaccggaaaa attgacactt
    32461 acgtatgaac gaaaacaaac gcttcgttac ggtgaaaata gccatcaagc cgctgccttt
    32521 tatcagtccg ctcttctgga aaaatattcg atcgcagcag caaaacaact ccatgggaaa
    32581 gaactttctt ataataatat ccgagatgca gatgctgcgc tacggatcat gaaggaatat
    32641 gacgagccaa cggtagtcgc cttgaaacac atgaatcctt gtggtattgg gacagcatct
    32701 acgattttag aagcgtggga agcagcgtat gaagcagatc ctgtttcaat ctttggtggg
    32761 atcatcgttt tgaatcgaga agtagatctg ccaacagcag aacagatgca taagctgttt
    32821 ctagaaatca tcattgcccc ttcttataca caagaagctt tggaattact gcaaaaaaag
    32881 aaaaacatcc gattactgac agtagacttt gcgcaggaag aaaatcaaaa tcgagaagaa
    32941 acggtctcag tcttaggtgg acttcttgta caagatcaag atctggcaat agaaaatgaa
    33001 gaagagtgga aagtcgtgac aaaacgtaag ccgactccag cagaagcaaa agcattagtg
    33061 tttgcttgga gagctgtcaa acatgtgaaa tctaatgcga tcgtactggc aaacgaacgt
    33121 cagacagtag gaatcggagc cgggcagatg aatcgagtcg gttcagtaaa aattgcgatt
    33181 gaacaagcgc aagagaaaat ggaaggtgca gttttagcta gcgatgctta ttttccaatg
    33241 gatgattcgg ttgaatatgc agccaaacat ggtataaaag caatcattca gccaggagga
    33301 agcatcaaag accaagattc tattgatatg gcgaataaat acgatctagc aatggtcttt
    33361 actgatgttc ggcattttag acattagaga ggagtcggat aaatgaacat tttggtgatc
    33421 ggtgcaggtg gtcgtgaaca tgcaataagt aaaaaacttt tagccagtcc gaaggtggat
    33481 acggtgtatt gtgcgccagg aaatccgggg atgacaaaag atggtatcaa ttgtgtcgct
    33541 atcagtgagc gagatcattc agcgttaatc cattttgtta agaaagaggc tattgattgg
    33601 agtatcgttg gtcctgaagt tcctttgtta aatgggatcg tcgatgattt tatggcggaa
    33661 ggattgaaaa tcttcggtcc gacaaaagca gcagctctga tcgaaggttc gaaaagtttt
    33721 gctaaacaat taatggatac ttatcaaatc ccgacagcta aatccagaag ttttgaatgt
    33781 tacgaaaaag cagcagcgta tatcaaagaa aatggtgcgc caatcgtagt gaaagcggac
    33841 ggcttagcag ctgggaaagg tgtagtcgtg gctaccacag tgaaggaagc gctggatgcg
    33901 gcagaacaaa tgttgaacca gcatcgattt ggggatagta gcaaaaaaat cgtcgtagaa
    33961 gagtttttgg caggagaaga attctccctt ttggcgtttg tccgtaatac caaggtgtat
    34021 ccgatggtca tttcgcaaga tcataagcgg gcatttgata acgataaagg gccaaataca
    34081 ggcggaatgg gtgcttattc accagtaccg caaatttcaa aaaagatgat tgaaaaagct
    34141 gtggaagaag ttttaaaacc agcggctttg ggaatgaaag aactaggacg ctctttcacg
    34201 ggtgttttat atgcgggttt gattgctacg aaggaaggac caaaagtgat cgaattcaat
    34261 gcgcgtttcg gtgatcctga aacgcaagtc gttctttctc ggttgaagag tgactttgcg
    34321 caagtaatcg atgatttatt agagaatcgt acagtagagt taaagtggca gcaagaagga
    34381 tacaatgtag gcgttgtggt tgcagctgcc ggttaccccg aagaatatga gacaggaatg
    34441 gttctaccag attttctgga agaagagctt tctgtttact atgctggagt ttcctcaaat
    34501 aacggcaaac tagttggagc aggaggacgt ctttatttag tagaagcata cggtgagacg
    34561 atcaaagaag cacagaaaaa aatttacacc gcgttaatgg ataaaacgac agatggaaca
    34621 ttttatcgta cagatattgg agaaaaagct gccaatagcg aactgatcgt gaagtaaatc
    34681 agctgcttcc atttataaaa aatacaacaa acataatcgg aagcgccgat tttagtgaag
    34741 ccttttcata aagagtgtgg tacacttttg ttgtgtatat aaataaggag gagttcagat
    34801 gaaaaaaatt caattaggta cttctgatca gaaagcagct gcagtgatct taggctgtat
    34861 gcgtatcaac aatgcggaag atccagtaaa agtgattgag acagcttatg aaaacggcat
    34921 tgattttttt gaccatgcag atatttatgg aaacggtgaa tgtgaagaaa tctttgcaga
    34981 tgctctagca aaaacatcaa tcaaacgaga agatcttttt attcaaacaa aatgtggaat
    35041 cgttccaggt gtgatgtttg atttttctaa aaaacatatc attgaatctg tagaaaaaag
    35101 tttgacccgt ctgaaaatgg attatgtgga tgctttactt cttcatcgtc cagatacatt
    35161 ggtagaacca gaggaagtag ctgaagcgtt tgatgaattg gaacggtcag gaaaagttcg
    35221 ttattttggc gtcagcaatc aaaaaccaat gcaaatcgaa ttgctgaaaa aatatgttcg
    35281 tcaaccatta gtagctaatc agctgcaatt tggcttgaaa catactggaa tgatcgatca
    35341 agggattcat gtcaatatga cagatgaagc aagtatcgat catgacggta gtgtacttga
    35401 ttattcccga ttgcatgata tgacgatcca agcatggtca ccataccagt atggattttt
    35461 tgaaggtgta tttatcggga acgaaaaatt ccctgaatta aaccaaacat tagaagaact
    35521 agcagctaaa tatcaaacga caccaactgg cttggcttct gcttggattt tacgccatcc
    35581 agccaatatg caagtgatcg ccggtacgat gaacgtaggg cgaatcaagg aaatcgctca
    35641 agcttcagaa attaatatgt ctcgggaaga ttggtacgaa ttgtaccgtg ctgctggaaa
    35701 cattttacct taaagattgt cataagcagg tcaaaagggc tataaattaa aaagacagaa
    35761 taacttgaaa gctgttttca gcttcgagat attctgtctt tttttattgc aaatggaaag
    35821 agtatcattg tacggatttc gtttattagt tatttttgtt tttaaggaaa agctgtgtcc
    35881 gatattcttt tggagaaatc ccttgttttt tcttaaataa ataactgaaa tagttagggt
    35941 cattataacc aatttcaaaa gcaatatctg aaatacgata gtctgattgc tgcaataatt
    36001 tttttgctaa ttcgattctt tgttctgtca gataatcgat gaatgtttgg ttaaacgatt
    36061 gagaaaaaat cgtactgaaa tgagagggac ttaatgcaac ttgttgagcg acccaagtta
    36121 aggacatatc tggatcggta aaattttctt tgataaaatc caatgcatgg ttcaaaattg
    36181 gctgatattt gttccttgaa ggctgtgagg gcagagcagt taagaaagaa atgaacatat
    36241 aaactgtcga acggtaaagc gagtcgtcgg cgctgattgc taagcgttga ctggtggatg
    36301 tgcaatgaac catttcttgc gggattttct tttctttcag gcagacatgc tggagtagct
    36361 tagtcaagac aaataaacga tataatcgtg ttcgagttgg tgtgccttgt ggtttcgtca
    36421 agtgttcgat gtacttagat acttcgtttt tcgataatga agacaaatca agtgagaggt
    36481 caaagtaaaa gacagaatca actggaagtt tcgcttcttg aatcaaatcc tcatagctga
    36541 taatttgttc tttaagggaa ctggcggttt caagtatcat ctgcgtgatc tcaaaagatg
    36601 caggtaattc gctgattctt tctgcgacag gaccaatggc gacagaaaaa ttattttttt
    36661 gtcccttttc taattcatgg accaacgttt gggctacctg ataactggtc tcgatcacat
    36721 tttcttcaag agaatcaact attaaaaatt tgatgaatcg agaggaaaca gcagagaaga
    36781 tcacttgttg attctcccta aataaaaact tcaaataatc actgagatga gcgtaatctt
    36841 caaagtctgt actgacttgg tttgctgcta ataatacggt catttttttc cctgctaaag
    36901 agcgattgaa agattcagca agtttcaatg tttcactgat cgtaagtgag cctttgaaca
    36961 aaccgttcaa gaaatgattt tttttcaatt cgaaaacaag atcagaagaa gtgtgcgttt
    37021 ctttttgctg caaatctaaa gcagttactg ctttttctat tgcttgtttc aattcgctac
    37081 ttttaatcgg tttaagcaga taatcatctg cctgtacctg gattgctcct ttcatataat
    37141 cgaaatcgtc gaatccacta ataaatatga gacgagtcca aggaagtagt ttccttgctt
    37201 cttttgaaaa agtcaacccg tccatgaaag gcatttggat atcagtcaga atgatgtcgg
    37261 gctgtaagtc gataattgaa gacagtgcca tctcaccatc tccagcttcg ccgacataag
    37321 tgattggata ataagaacca aggacagtta tttgttcccg caagttattg cgaatgaggt
    37381 attcgtcttc gatgataaaa actttataca tgtttgtttc ctccaattgt tttgggagat
    37441 agagggatca tcagtgtgac agttgttcct tctcggtatt tgctgtcaat cgtgataggt
    37501 ttttgatcat ttccgtaata aagaaggaga cgcttgttta cgttgtaaag tccgtagccg
    37561 atactgaaat ctgaatcgat ccctttggct aactctttac gtatttctgc cagtttttct
    37621 gcagggatgc caatcccgtt gtctataact ttgaattgga tcatctcatc aattttgcat
    37681 gtggtaatac gaataaatcc tttgtgacgg acgtacttcg ttccatggta tacagcattt
    37741 tcaatcaatg gctgcaagat catttttaaa atagaaacag gaaaaagtgt ttctggtata
    37801 tcgatcttat agtcaagcat atggccgtat cttattttta agatgactag ataatcattg
    37861 atatggctaa tttctttttc aagaggaatc cagtcttgtc ctttgcttaa agacgtacga
    37921 aaaaagccgg aaagtgcatg ggtcatagtc agagcttctt caaagcagtc ttgttcgatc
    37981 aaagaaataa tggcatccaa actgttataa ataaaatggg gagtaatctg agcttgcaat
    38041 acacgaactt cactttgtgc taaatggtat tgtttcaaag cgttctcccg taaagactgg
    38101 tttagatctt ccgccatttt attcatgcta gcggtaagtg tttgtaattc cagtgtttcc
    38161 ggcagggtta aacgaaagcc aaggttccct gaagaaagtt gttctgacat ctcgatcagc
    38221 tgattgatcg gttcttggac ctttctctct aaaaagcgac gattcttttt cgcatagaaa
    38281 aaaatggtac taagaactcc aagttccact attgttaata gaatgagcga gcggacaagt
    38341 gtcgtatttt ttttgcttgc taagtcgatc tccacacgaa caaaatcttg taagatatct
    38401 gacagcagtt gagtgacaga atctacctga ttgatgatct cttcattggt atccataaaa
    38461 tcttttgcca agatattatt gatcagctcg ttttgataat cttccagtgt atcgatcgta
    38521 cgtagcgata catctaacgt actaatttct ttaagtgtat ttgtattatt tttgatctct
    38581 cgaatatcat tcctaagttc ttctaggata ttttcctcat tgaactcatc tacggttact
    38641 tggccagaaa tcaagtccca catactttcc aaaacttttt gatcaacctt caaagcaatt
    38701 gcatctgctt tttggatatt tgcgatcgtc tgttgataaa tcaaaagctg ttgcgaatat
    38761 aacagtatgc tcagtagcaa agggataaca gcaaatagaa gcatggcttt gtttgcttgg
    38821 gcaaaaatct gttttatgct taaatttttt gtcatgatac ttctccagtc aataatttct
    38881 ggttgggatg ttagctatat tctgctggga aaagacagtc tcggaaataa aaatatcttt
    38941 aggtaatgtt tttcctgttt gaatatttcc aaaataacga gtaacggtat tggctacata
    39001 ccagccgaca tcaggtttac actcgactac acaattgacg attcctgagc gtagcttctc
    39061 gatcatatct tcttgtccat caatagttac aatgatcaaa tcttctccag gtttgattga
    39121 tgtttctttt atcgcagcta aagcaccgtg agtcatttca tcactatggc tgtataatac
    39181 atcgatttcg gataaatcat ttgtttctaa atatcgtttc atctggtctt ttcctttcat
    39241 ccgaataaaa tcaccgacaa ttcggtgaac aatagtcatc ggaggtttat ggtcgatggt
    39301 tccatctttt tttagggttg gtttacgatt gattgattcc aaaaatcctt cggagcgtag
    39361 cttggtcggt gtggagttct ctgaaccagc aagttctagg attctgattt cctgtttctt
    39421 tgaatttgtg aagtgattgc tgacaaataa acccgcccga tttccttctg ctttgaaact
    39481 ggggccaatg tgggtgacga aaagctcggg atcattcgtt tgaatatgtc tgtcgacaag
    39541 tatgacaggg atccctgctc gctttgcttc ttttaataca gagtcccacc cggattcttg
    39601 caaaggagta aaaatgatca tatccacttt ataggcaatg aacgtccgta tatcttggat
    39661 ttgccgttcc tgattcatgt agccatttcg gtagagaact tggtaatctt ctttttcaag
    39721 cgcagtgata attgattcag tatgcttttt ccgccagcta ctctccgttc ctgattgcga
    39781 aaaaccaacg actagtgggt caggtgcttc ctttgtatta ggtgtacacc ccatcatttg
    39841 gtaagcgatt acaacaaggg ctaaaaaaaa taaaacacgt ttcactttaa atcactccat
    39901 ctggatttgt tagtactatc ttatcagata aaagggaaaa tcaaagtcaa aaggaatcaa
    39961 tcgaaaaaaa tccaagaaac ttaaaaaaat ccaagacaaa aaaagtacac ctaaaaaatt
    40021 taaagtaaat cccataaaaa aatcaatgtt aacgctttct ttattagcta tactcggtgt
    40081 atcaattgaa atgggggata aaaaatgaaa aacaaattta gaaagattgt tgggactatc
    40141 gctattttga ccgcaagcat tctattaagt gcgtgtggca attcaggatc tgcagatgat
    40201 agtacggggt atgtaggaat cgctatgccg accaaatcag cagaaagatg gatcgctgat
    40261 gggaacaaca tggtctcgga attagaaaaa ctgggttata aaacagatct tcaatatgga
    40321 gaagataaag tagaaaatca agtagcacaa atagaaaata tgattacaaa aggggtagat
    40381 acacttgtga ttgcttctat cgatggttcg gctttaactg atgtgttagc taaagcaaaa
    40441 gaagcagata tcaaggtgat cgcctatgat cgtttactga tgaattcaga aaatgtcgat
    40501 tattacgcga cttttgataa ttttggagta ggtgtatcgc aagcagctta tattgaagag
    40561 cacttaggat tgaaagaagg aaaaggacca ttcacgattg aattatttgg tggctcgcct
    40621 gacgacaaca acgcactaat caattacaac ggagtgatgt ctgttttaca accatatatg
    40681 gacaacggtc agttggtcgt gccatctgga cagacgagtt tcagtcaaat cgctacgctt
    40741 cgctgggatg gttctacggc gcaagcaagg atggataatc tgttaagcgc aaattatact
    40801 gaccaaacat tggatgctgt tttgtcgcca tatgatccaa taagtttagg aatcatttcg
    40861 tcattaaaag gcgtggggta tgggagtgaa agtaaacctt tacctgtgat tactggacaa
    40921 gatgcgacag ttgctggcgt taaatcgatc attgccgggg aacaaacaca aacgatcttt
    40981 aaagacacac gtatcttagc aaaaaatacg attgaaatga tcaaagcaat cagtgatgga
    41041 gaagaggttc cggtcaatga tactgaaact tatgataatg gggtgaaaac tgtccctacg
    41101 tatttagcaa atacagtatc tgtcgataaa gataattatc aagcagagct gatcgacacc
    41161 gattattata aagaatccga tctgaaaaat taagaggaac caaacaagga actaaagaga
    41221 tctaagtcag agagaggata agaattatgg cggattgtat tttaaaaatg gcagatatca
    41281 ccaaaaaatt ttctggaatc cgagcgttag attgcgtgaa tctgatgatt gaacgtgggg
    41341 aaatccatgc attgtgcgga gaaaacggag cgggaaaatc aacattgatg aatgtcttga
    41401 gcggcttgta tccatatggc tcctatgacg gggaaatctt ttatgatgga aagctgtgtc
    41461 aatttaaaga tttgaaagat agtgaagaaa aaggcatcgt catcattcat caagaattag
    41521 cactaagtcc ttatctttca ataaaagaga atatttttct cggaaatgaa caagcagaaa
    41581 gaggcgtgat tgattgggaa ctgacagaaa agaaaacata tgaactgctg aataaagtcg
    41641 gtttgtctat cgacccgaat cttctagtat cccagattgg cgtagggcaa cagcaactag
    41701 ttgaaatagc taaagcatta tcaaaatccg tccgtctgtt gattttggat gagcctaccg
    41761 ctgcattgaa tgaagaagaa agcgcgaatt tgctgagatt gatccgagag ttgaaagagc
    41821 aaggtgtaac ctccatcatt atttcacata agctgaatga aatcgtggat atcgcagatc
    41881 gaatcaccat tttacgggat ggacagacga ttgagacact agaaaatgaa atgatcagcg
    41941 aagagcatat tattcgcgga atggtgggca gagatttagt tgatcgttat cctgaaagaa
    42001 aaccggatat tggagaagtt tattttaaag tagaagactg gacggtctat caccctcttg
    42061 atcacgagcg aatcataaac gaccacatca acttgcattt gaaaaaagga gagattgtag
    42121 gaatagctgg actgatggga gcgggcagaa ctgaattcgc tatgagtcta tttggacatt
    42181 cttatggaag caagatatcc ggacgtatat taaaggaagg ggcagagata tcagttaaga
    42241 ccgttccttc agccattgca aacggactcg cttatgtctc ggaggaccga aaatctttag
    42301 gactgaatct gctgatggat attcgggaaa acgtgacgct gagcagtttg gataaaataa
    42361 gtcaaaaagg agtattagat aaagaaaaag aagtaactga ggcagaaaat ttccggaaaa
    42421 agatgcgtat aaaaacaaac tccatccatc aaattgtcag tagtcttagt ggtgggaatc
    42481 aacaaaaagt cgttttatcc aagtggctga tgacacaacc cgatattctt tttttggatg
    42541 agccaacccg tgggatagat gttggggcaa aatatgagat ctacacgatt atcgaagaaa
    42601 tggcagcaaa tggcaaagct gtctgtctta tctcttctga acttcctgaa atattaggga
    42661 tgtgtgatcg aatctatacg atgaacgaag gacgtattac aggagaagtc tcgcgagaag
    42721 atgcagatca ggaagtcttg atgaaattaa tgacgaaaga agaggtgggt taagttggaa
    42781 caggcaaaaa atcttacgga taaaaaagag aaaaaactaa atttgaaaag tagagcagct
    42841 gatctttttg gtcgctacag catggtgatc attttagcgg gactacttat tgcgtttcaa
    42901 ttgatgacgg atggtatttt ctggcgtcca ttgaatataa ctaaccttgt tctgcaaaat
    42961 agccatatat tagtactagc tgcagggatg ttattagttg tgctcttagg tcatgtggat
    43021 ttgtcggtag ggtcagtgat ggcgtttgtt ggtgcaattg cgggcatgat gatggtcaat
    43081 cgccaaatga acccgtggat gacagttatc gcatgtcttg cagtaggcgg gctgatcggc
    43141 gcatggcaag gtttttgggt agcttatgca gggataccgg cgtttatcgt gactttagca
    43201 ggattgctga tgtttcgtgg actgacacaa gttgttctag gaggccaatc tctagcacct
    43261 tttccagctg ttttccaaaa aatgtctacg ggttatttac cagacttaag cgaaggaagc
    43321 agccttcact tcttgacatt gattttagga atgatcatca cgatcgtgtt agttgttggt
    43381 caatggcgaa caagaaatcg tcggaaaaat catttatttg aagtggaatc tccaacagct
    43441 ttcttggtaa aggcggtatt tacagcagtc gttgtactag gaataactta tatctttgcc
    43501 tcttatcaag ggtatccgat tattttgatc attcttggtt tgatcgttgc agcatatggg
    43561 tttttgacaa ataaaacagt agcaggtcga cagatttatg cgacgggcgg aaatcgaaaa
    43621 gcggctgaac tatcagggat caaaacaaag cgaatcacgt tctgggtatt cgtcaacatg
    43681 ggagtcatgg cagctttagc tggattagtt ttagctgctc gattgaatgc ggcaacacct
    43741 caagcaggta catcgatgga actggatgca atggcggcag tatattttgg tggtgcttcg
    43801 acttccggcg gcattggaac aatcatgggt gcgattgtcg gtggcttggt catgggtgta
    43861 ttgaacaatg gcatgtcgat tttaggcgtc ggggtagact ggcagcaggc aatcaaagga
    43921 ttgatcttgc ttttagccgt tgtgctagac ttgtataata agaaaaaacg aacaacgtag
    43981 gagaacgccg gttattcaga aaaaagactg tgacaagaca tttgtcacag tctttttttc
    44041 gctaaaagcg aacattcatt gtttcgtttg tatagactaa aaataatata tgttttttta
    44101 ccattcgtat aaattctctt tttgctcttg atttttttgc ttaattgagt taaattacat
    44161 agggcgctaa aaaaagcctt gattaaatta ataatgttcg tgttttgctg gatgtgaaca
    44221 tcaggaggat aatgtaatga aagtatttga ttacgaagat attcaattaa ttcctaataa
    44281 atgtatcgta aatagccgtt ctgaatgtga tacaacggtc acattaggta aacatacatt
    44341 caaaatgcca gtagtgcctg ccaacatgca gacgattatt gatgaaacaa tcgcagaatt
    44401 cttagcggaa aatggttatt tctatatcat gcatcggttt gatgaagcag ctcgaattcc
    44461 gtttatcaaa aaaatgaaaa agcgtggatt gattacctcg atcagtgttg gcgtcaagaa
    44521 agaggaatat tcctttatag agaagttggc agaagaatcg ctaaatcctg attatatcac
    44581 tatcgacatc gcgcatggac atgctaactc agttattgat atgattcagc atattaaaaa
    44641 atatttgcct gaaacttttg tgattgccgg taatgttggt acaccggaag ccgtccgtga
    44701 attggaaaat gcgggcgcag atgcaacaaa agtcgggatt ggtccaggaa aagtatgtat
    44761 tacaaaaatc aagacaggct ttgggactgg aggctggcaa ctggcagctc ttagatggtg
    44821 tgcgaaagca gctcgcaagc cgatcatcgc tgacggtggg atcagaacac atggcgatat
    44881 tgcaaaatct gtccgttttg gtgcgacaat ggtcatgatt ggttcattgt ttgccggtca
    44941 cgaggaatct cctggcgaaa caaaagtcga aaatggaatc gtgtataaag aatactttgg
    45001 ttctgcttca gaattccaaa aaggcgaaaa acgaaatgtt gaaggaaaga aaatctggat
    45061 ccaacacaaa ggatctttga aagatacact agtggaaatg caacaagacc ttcaatcatc
    45121 tatttcttat gctggaggaa gagatctgga agccattcga aaagttgact atgtcatcgt
    45181 gaaaaattcg atttttaatg gagacacaat ctaaaaaata aataaaatat taggatgttg
    45241 tgaaaaagtt gtcctgcatt aagtaataag aacagccaaa caaaaatagt tctttatatg
    45301 ttttgtttgg ctggaattat tatcgcagat acaagctttt gaacatcatt attcagaata
    45361 agggactgtg ataagatttt tgtcacagtc ccttatgttt tgcaaaaaaa gtttttcttt
    45421 tttctcgtaa attcggtaaa atcaaaagaa aaaatagaca atagaaaaga gaagcttatg
    45481 tgggaaaaag tagagaaaaa acaaggaccg atttatcgtc aaattatgga acagattatg
    45541 agagaaatcg aaaacggaag gatcaatcct ggaagtcaac ttgaatcaga acgaaaacta
    45601 gggcaacttt ttggtgtgaa tcgttccacc gttgtccatg cattggaaga gcttagggag
    45661 cttggggtac taacgagcaa acgtggcagc ggatggtttg ttaatcagac tgaatggggg
    45721 aaattcgctg ttccaagaat cgattggcgg caaatgatct ctcctcgtta tgagcagacg
    45781 gactggtatg agcaaaaaat aagagaagca aagcagatcc aaaaaacatc gtttcttgat
    45841 ttatacgcta gcgagatgcc agatgagctt ttgccgaatt ttgagtttcc ttcttattct
    45901 cttgaagaaa tcttagcgga agaaaaagaa atggatcttt taggctatac tccgttacgt
    45961 aacaaaatca aacggtattt ggaaagtaaa tttgaattgg cattttcccc caaccagctt
    46021 cttgtgactg gtggcggtca gcaagcaatc tttttgattt tacaaacgat tctttcagct
    46081 ggagagggga tagctgtaga gtcaccttct tttttttacc gattacctct tttcaaagct
    46141 tcaggaacgc gtttatttgg gataccgatg gatgaagaag ggatcgactt agaaaaactg
    46201 aaagaatcga tccataaaaa taaattgaaa gcagtgctta tcaacccgaa ttttcaaaac
    46261 cctacaggaa aagtgatgag tcaaaaacga cgagaaaagc tagtagaatt gtgtcgacag
    46321 tatcggcttc caattattga agacgatgta tttacggatc tttcatttct aaaccaagaa
    46381 gaagtccttc ctatacgaac gattgatccg gataatgtgt tatacgtcgg ttcgttatct
    46441 agggttttag gaaaaacaac gaaaatcggt tgggtgatag gacctgagac ttttatctcg
    46501 caactagctc aagcgcaaga aatgatggag ttttcgatga atatccttac acaaatcaca
    46561 gtggctaatg tatttaatga agcaattgat ttgaaaatgc aagatgtaag aaaaaagttg
    46621 aaagaaaaaa gccgactgat aagcgcttgg ggagattcac aatcgttttt caagcttcat
    46681 tcaattttag gtggttacta tgcctggatt acttgggatg ggaaaaaact agaccccgaa
    46741 ctagcagaaa aagtagtaga tatgggtctt ggaattgcac caagtctact ttttgggcaa
    46801 gatataaatg gaatcagaat caattacagt aggctggatg aaaaccaaat accgttgttt
    46861 tattcaaaga tgaaaattct agaaaagtgg ttaacagaat aatttcacaa agtaaataga
    46921 ttaaagaata taacagcttg gatttaaatt tcaagctgtt tctttttttt cggaaaaaga
    46981 atacgatata aagaaactaa gaaaaaacca ttatttgtac gtccgttcac gatgtgtaaa
    47041 taaaataaat gtttgcaaca aaactgtata acaccaacgt ttttaaatag aaacagatgg
    47101 ttgtaagttt gattagaaaa tagaaaaaat gcagatgaaa tataaaacgc tttccttatt
    47161 gtgattttat tcactaatgc tgttaatatg cggattggca taatttcctt tcatcgtgaa
    47221 aatttgtgct tttagcttgt atttctcata aatccatgat aatttattaa tgaagacggt
    47281 taaatagtga tacagtttta ttcactgttt caatcgcaga atgaagagat tttcttatag
    47341 atgagagagg aatgtgtgac aaatggcaaa caaaaaagca ccgatcgact tccaagcact
    47401 gctagatgaa gtcaatgcag atttcccagt atatcaagca cttgatcaag atggaaacgt
    47461 agttaacaaa gatttagtac ctgatttatc cgatgatgaa ctcgttgaat taatgactca
    47521 tatggtatgg tctcgtgtat tagaccaacg ttcaacagcg ctgaaccgcc aaggacgcct
    47581 aggctttttt gcaccaactg ctggacaaga ggcaagtcag ctggctagtg cttacgcatt
    47641 tgataaagaa gatgttcttc ttccaggtta tcgggatgta cctcaactag taaaacatgg
    47701 tttaccttta tctcaagctt ttttatggtc tcgaggacat gctgcaggta attcttatcc
    47761 ggaagaattg aaagctctac caccacaaat tatcatcggt gcacaatatg tacaagcagc
    47821 cggtgttgca ttaggtttga agaaacgaaa caagaaaaat gtcgtcttca cttatactgg
    47881 tgatggcggt tcatcacaag gtgattttta cgaagcaatc aatttcgctg gcgcttacca
    47941 tgcaaatgcc gtattttata tccaaaacaa cgggtatgcg atctctacac ctcgtgaaaa
    48001 acaaactgca gcaaaaacac ttgcacaaaa agctgtcgca gctgggattc ctggtattca
    48061 agtcgatgga atggatccgc ttgcagtata tactgtatct aaaatggcac gggaatgggc
    48121 gatcagtgga aatggaccag tcctaatcga aacactgact tatcgttatg gaccacatac
    48181 actatctggt gacgatccaa cccgctaccg tacaaaagac acagatgacg attggcagaa
    48241 aaaagatcca ttgatccgct tccgtaaata tttgacggaa aaaggacttt ggtctgaaga
    48301 aaaagaagaa caagtcatcg aagcaactaa agaagaaatc aaagcagcta ttgctgaagc
    48361 cgacaaagta ccaaaacaaa aggtttcaga tttcttgaaa aacatgttcg aagtatctcc
    48421 acaatcaatc aaagaacaaa ttgcaattta tgaagcgaag gagtcgaaat aatcatggca
    48481 caaaaaacaa tgatccaagc aatcacagat gccttagcac ttgaactaga aaatgacgag
    48541 aatgtcgttg tttttggtga agatgttggg aaaaacggag gagttttccg ggcaactgaa
    48601 ggattgcagg aaaagttcgg agaagaccga gtattcgata ctcctttagc tgaatctgga
    48661 atcgcaggat tgagtttcgg tcttgcgtta gaaggatttc gtccagttcc tgaaatccaa
    48721 ttctttggtt ttattttcga agcaatggac gaagtagtag ctcaaatggc tcgtacaaga
    48781 tatcgaatga gcggcactag aaatctaccc atcacaattc gttcgccatt tggtggcggt
    48841 gttcatacac cagaattgca ttcggataat ttagaaggtt tgatcgctca gtctcctggt
    48901 attcgagtag tgattccttc caacccttat gatgcaaaag gactattgat ttcttctatt
    48961 agaagtaacg atccggttgt tttcctagaa cacatgaaac tatatcgctc attccgagaa
    49021 gaagtgccgg atgaagctta cgaagttcct ttggataaag cagcagttac tcgtgaggga
    49081 acagatgtat ctattatcac atacggagca atggtgcgtg aagcaatcaa agcagcagac
    49141 aatcttgcaa aagaaaatat atctgttgaa atcattgatc ttcgtacagt tgcgccatta
    49201 gatgtagaaa cgatcattca atccgtggaa aaaactggtc gcgtagttgt tgtccaagaa
    49261 gcacaacgac aagcgggcgt tgccgcgcaa gtagtttctg agatctcaga acgcgctatc
    49321 ctttcattag aagccccaat cggacgagtt tctgcacctg atacagtctt cccatttgga
    49381 caagcagaaa atgtctggtt gccaaatgca aaagatatcg aagacaaagt aaaagaaatc
    49441 gcggaatttt aagaaaagaa gggacgaaac aaagtcatgg cttatcaatt taaattgccg
    49501 gatatcggtg aaggaatcgc agaaggtgaa atcgtcaaat ggttcgtcaa accaggagat
    49561 acgatcaatg aagatgatac attactagaa gttcaaaatg acaaatcagt agaagaaatc
    49621 ccgtcacctg ttacaggaac ggttaaaaat gtgattgttc cagaaggtac cgtagcaaat
    49681 gttggggatg tattagtaga aatcgatgca ccaggacacg aagacaatga aggggacagt
    49741 ggtgtagccg cagaatccca aactccagct aaaccggctg ctgaacccac tgttgataca
    49801 gaatcagctg gatcgtcaag cgaaggagtc ttccaattta agttaccgga tatcggtgaa
    49861 ggaatcgcag aaggtgaaat cgtcaaatgg ttcgtcaaac caggagatac gatcaatgaa
    49921 gatgatacat tactagaagt tcaaaatgac aaatcagtag aagaaattcc gtcacctgtc
    49981 acagggacag ttaaaaacgt gattgttcca gaaggcactg tagcaaatgt tggggatgta
    50041 ttagtagaaa tcgatgctcc tggacacaat agtgcaccgt caactagtgc gccatcagct
    50101 gaagcaccaa aagaaaaagt ggaaacatca ggttcagcaa gtgtcgttga agctgccgat
    50161 ccaaataaac gtgtattggc tatgccatct gttcgtcaat ttgcccgtga aaaagatgta
    50221 gatatctcac aagtaactgc aactggaaaa ggtggcagag taacaaaaga ggacatcgaa
    50281 aacttcttgg caggtggtcc aagcagtgca ccagcgaaat cagaagcgcc agaagcggca
    50341 gcaccgaaag aagcagctcc tgcagcagaa agcaaaccag ctgcaccagc aaaaccattc
    50401 aagtccaact taggagactt ggaagaacgt gtagcaatga cgccaacacg taaagctatc
    50461 gctaaagcaa tggtcaacag taagcataca gctccacacg tgacattgca tgatgaagta
    50521 gaagtgtcta aactatggga taatcggaaa cgatttaaag aagttgctgc tgcaaatggt
    50581 acgaaactta ctttcttgcc atatgtcgtg aaagctttaa cagcgactgt taagaaatac
    50641 ccagtattga atgcatctat cgacgatgca aaccaagaaa tcgtttataa acattactac
    50701 aatatcggta ttgcaactga tacggatcac ggactatatg taccaaatgt gaaagatgca
    50761 gaccgcaaag gaatgtttgc tattgcagac gaaatcaatg agaaagcaaa attagctcat
    50821 gacggcaaac tatctgcaga agatatgcgc aatggaacaa ttacgatcag caatatcgga
    50881 tctgtaggtg gcggttggtt tacaccagtc atcaactatc cagaagtagc tattttaggt
    50941 gtaggaacga ttgcacaaca accaatcgta aatgctgaag gcgaaatcgt tgtcggtcgt
    51001 gtgatgaaac tgtcattaag tttcgatcac cgtatcgtag atggagcaac tgcgcaacaa
    51061 gcaatgaata atatcaaacg tcttttagct gatccagagc tattaatgat ggaaggatga
    51121 taaacaaatg gtagttggag attttgctgt agaattagat acagttgtaa ttggtgcggg
    51181 acctggtggc tatgtagctg ccatccgcgc tgctgaaatg ggacaaaaag tagcaatcat
    51241 tgaaagagag tatattggcg gtgtttgttt gaatgtcggc tgtattcctt caaaagcact
    51301 gatagctgca ggacaccatt atcaagagtc actagattct gaaatgtttg gagtaactag
    51361 tgaaaacgtc aaactagatt ttgcaaaaac acaagaatgg aaagaaaaca aagttgtcca
    51421 tacgttgact tctggtgttg gtttcctatt aaaaaaacat aaggttgaaa caatcgaagg
    51481 agaagcgttc ttcgtagatg atcacacact acgcgtcatt catccagatt cagctcaaac
    51541 ttattcgttc aataacgcaa tcatcgcaac aggttcccgt ccaatcgaga ttccaggatt
    51601 taaattcgga ggacgtgtgt tagattctac tggcggatta gcattgaaag aagtacctaa
    51661 gaaatttgtg atcatcggtg gcggtgtgat tggtgccgaa ttgggcggag cgtacgcaaa
    51721 cttaggagca gaagtaacga ttcttgaagg ctcaccacaa attttaccaa cttacgaaaa
    51781 agatctagta aaattagtag aagatgattt caagaaaaaa ggcgtaacag tcgtaacgaa
    51841 tgcaatggcg aaagaagcag tcgataacgg tgacagcgtg acagtgaaat atgcagtgga
    51901 cgggaaagaa gaatccgtta ctgctgatta tgtgatggtc actgtaggtc gtcgtccgaa
    51961 tacagatgat atgggcttag aacaagcggg tgtcgaagta ggagaacgag gattgatcac
    52021 ggtggataaa caaggacgta cgaacgtacc taacatctat gccatcggtg atatcgttcc
    52081 aggggcggca ttagcacaca aagccagtta tgaagcaaaa atcgctgctg aagcaatctc
    52141 tggcaaaaaa gtagctgtag attataaagc aatgccggca gtagccttca ctgatcctga
    52201 attggcttct gtaggtatga cgatcaaaga agcaaaagat gctggtatcg aagcaaaagc
    52261 atataaattc ccattttcag ggaacggtcg ggcattatcg cttggtaaaa cagaaggatt
    52321 catccgtcta gttacgacga tcgaagataa cgtgcttatt ggcgcgcaaa tcggtggagt
    52381 cggcgcaagt gatatggtct ctgaattagc tttagcaatc gaatcaggaa tgaatgctga
    52441 agatatcgcc ttgacgattc atcctcatcc atctcttggc gaaatcgtca tggatgcttc
    52501 ggaattagca ttaggtttac caatccatat ttgatttgaa taatacaggc gaaacgcaac
    52561 tgaaaaatca gttgcgtttt gttttttaga attatcaata atattattat gtaaacttaa
    52621 aaatatgaca acttcttggt ttattaccac ttcctatgct acactgaaga ggaatatgaa
    52681 ataggagagt tgaagatgca agaatatcag tatccacttg atttagattg gacaacagac
    52741 gaaatggtca ttgtaatgaa gatgtgggaa gatctggaac gtgcgaatga aaaagggata
    52801 aacaatgaag cttttttgaa gacttatcag cagtttaaaa ctgttgtcaa atccattggt
    52861 gaggaaaaac gattgggacg ggaatttgaa aaagcttccg gttattcttt atatcgtaca
    52921 gtgcagcaag caaaaaaaaa tccaaacaaa actttgagaa tgaacgggtg agataaatgg
    52981 aacagatgat tgatcatatc aagtcctggc ttgaagaagc tggtgagaaa atcaaatctt
    53041 ctcaacaaac attaacaatc tcgcaaaaat caaatcgaac ggatctagta acaaatgtcg
    53101 atcgaaacat ccagaatttt ctaatcgaaa aaatccattc ctttgatcca gaggcgaaaa
    53161 tattggcaga agaagaaggg tgtaatcaat tatcggatct cgatggaaga gtctttatca
    53221 tcgatcctat tgatggcacc ttgaattttg tgattgaagg ggaaaatttt tgtattatgc
    53281 tcgctgttta tgaatccggc gttggaaagc ttggtttcat ttatgacgtg atgagaaatg
    53341 aacttttttg gggtggaaaa ggaataggcg tgtataaaaa tgatgagcca ttgcctagac
    53401 cagcaaataa atccttatcg gaaggcttac ttggtgtgaa tagttatctt ttcggtcata
    53461 ataaatatgg aatccgagaa attgcggaaa gcagcatggg gacacgtatg tacggatgcg
    53521 ctggtcttga actagtggca atcttgaaag gaaaccacat tgcttatatt tcaaacctta
    53581 gcccttggga ttatgcagcg ggaaatgtct tattggaaga gtttggtatg gtaacaagcg
    53641 gtctttttgg tactcctttg acatttgaaa aaagggaata ctatttagca gggacttctt
    53701 gtgcatatgc agaaatcgca gaccttttga aaaaagaagg ctgaaaaaaa ggtagaaatc
    53761 attcacaaaa atgataaaaa cgagcaaaag attaattttc tcgaaaaaat gaaaacattt
    53821 tactatattt catgaaaaaa gtctgctata attagcagtc gagtaaaatt tgccctgtca
    53881 taaagaacca ataaaaaagg agttagttac attgaattat agaaacgata tccgtaacgt
    53941 cgcaattatt gcccacgttg accacggaaa aacaacatta gttgatgaac tattaaaaca
    54001 atcagataca ttagacgcac atacgcaatt gcaagaacgt gcgatggact caaatgcgct
    54061 agaaaaagaa cgtggtatca cgattttagc caaaaacaca gctgtagact ataaaggtat
    54121 tcgcgtaaac atcatggata ctccaggaca cgcggacttc ggtggcgaag tagaacggat
    54181 catgaaaatg gttgacggcg ttgtgttggt cgtagatgcg tatgaaggaa caatgcctca
    54241 aacacgtttt gtattgaaaa aagcactgga acaacatatc acaccaatcg ttgtcgtaaa
    54301 caagattgac aaaccttctg ctcgtcctga gcatgtcgta gatgaagttc ttgaactatt
    54361 catcgaatta ggagcagatg atgatcagtt agactttcct gtgatttatg catctgcact
    54421 aaatggtacg tcaagcttgt cagatgatcc agcagatcaa gaaccaacca tggcacctat
    54481 ttttgataca attattgaaa aaatccctgc tcctgtcgat aacagcgacg aaccattaca
    54541 attccaagtt tcattacttg actacaacga ttatgtaggt cgtatcggaa tcggacgtgt
    54601 atttagagga acaatcaaag taggagacca agtagcatta attaaattag acggaacagt
    54661 taagaaattc cgtgtaacga aattatttgg tttctttgga ctaaaacgtc tagagattca
    54721 agaagcaaaa gctggagact tgattgctgt ctcaggtatg gaagatatct ttgtcggtga
    54781 aacagttact cctgtggatc atcaagatgc gttacctatc cttcacattg acgaaccaac
    54841 attgcaaatg actttcttag ttaataattc accatttgcc ggtcgagaag gtaaattcgt
    54901 aaccgctcgt aagattgaag aacgtttgat ggcagaactt caaacagatg tatccttacg
    54961 agttgaacca acaaactctc cagatgcatg gacagtttct ggtcgtggag aattgcattt
    55021 gtctatcttg attgaaaaca tgcgccgtga gggatacgaa ttgcaagtat ctcgtccaga
    55081 agttattgaa aaagaaatcg acggtgtaaa atgcgaaccg tttgaacgcg tgcaaatcga
    55141 tacaccagaa gaatatatgg gtagtgttat cgagtccttg agcttacgta aaggtgaaat
    55201 gcaagatatg gtccatacag gaaacggaca aatccgtttg acattcttaa cacctgcccg
    55261 cggtttgatt ggttattcaa ctgaattcct ttcaatgaca cgtggttacg gaatcatgaa
    55321 ccatactttt gaccaatatc tgccaatgct tcctggtcaa attggcggac gtcaccaagg
    55381 ggcgcttgtt tcgatcgata caggaaaagc aacgacttat tctatcatga gtatcgaaga
    55441 acgcggtaca gtcttcgtag aaccaggtac agaagtatat gaaggaatga ttatcgggga
    55501 aaacagccgt gataatgatt tgactgtcaa catcacgaaa gcaaaacaaa tgacaaacgt
    55561 acggtctgct actaaagacc aaacatctgt catcaaaaaa ccaaaacaat tgacgttgga
    55621 agaatctttg gaattcttga atgatgatga atattgcgaa gtaacaccag aaagcattcg
    55681 cttgagaaaa caaattttag agaaaaatgc tcgtgaaaaa gcatctaaaa agaaaaaata
    55741 atctgtaaaa ggatgaagag agaaaccagc ttgttataaa aaatagctgg tttctttttt
    55801 tgtccaactc ttttctgtgg agaagtcatc tttgtcaatg gacataaatt cagaaaatac
    55861 gccgaaagac gtttaaaaga cttttaaaaa acttatttct agagagtttt tgtttcataa
    55921 taagataatg tttcacgaaa ggagatcaac ttgtccttcg aagaaaatcg aagtaaaatg
    55981 gcaagagaaa ggagcgggaa gatgaacgac ttattaaaac aatactttgg ctatgatgag
    56041 tttagacctg gtcaaaaaga aattatccag aaagtcattg atcaggaaaa tgtattagga
    56101 atcatgccta ccggaagtgg gaaatcaatc tgttaccagc ttccagcttt actattagat
    56161 gggcttactg tggttgtgtc ccctttaatc tctttgatga aggatcaggt ggacgcggcg
    56221 aatcaattag gtatacccgc cacttttatc aatagctcgt tagatggtta cgaaacagct
    56281 agacgcttcc aagaaatcga tagacagcag taccgtttac tttatatcgc tcctgaacgt
    56341 tttatcatgc cggattttat ccaagcaatg aagcgatgga acgtccgtat gatcgctatt
    56401 gacgaggcac attgtatctc tcagtggggg catgatttcc gcccaagtta tttacagatg
    56461 gcgaaccagc tagatcaact gccaaatcgt cctgtaattg ttgctttgac agctacagcg
    56521 actgtgcaag tagctgctga cataaaaaga cttttaaaaa ttccagaaaa caaccatatt
    56581 cagactggtt ttgaacgaga aaatctacga tttcaagtaa ttaaagatca aaaaaaagaa
    56641 caatatctaa tcgaatattt aaagatcaac aaaaatcaat ctggtatcat ttatgcagca
    56701 acgagaaaag aagtagaccg tctctatcat ttgcttaaaa aattcgattt ttccgtgggt
    56761 agatatcatg gtggtctaaa tgagaatgag cgaacagaaa tgcaagaagc ctttttatac
    56821 gatcgcttgc agctgattgt agcgacaaat gcatttggta tgggtataaa taaaagcaat
    56881 gtccgttttg ttatccatta tcaaattcct ggctctctag aagcatacta tcaggaagct
    56941 ggtcgggcgg gaagagatgg tctttccagt gaagccatcc tgcttttctc tcctcaagat
    57001 atccaagtcc aaaagttttt tatccagcag tcccaaagag aagaagggca aaagcaaaaa
    57061 gaatatgaaa aattaaaagc gatgacagaa tacgtgtata ttgagtcctg tcttcagcaa
    57121 tacatcctaa actattttgg cgagacaagc agtccgtgca accgttgtgg taactgttta
    57181 gatgacagag aaatagtaga agtaacgaca gaagcacaga tggttctttc ttgcttaaaa
    57241 cgtatgggtg agaactatgg taaacaaatg ctgatgaaag tcttagcagg atcgaaagaa
    57301 caaaagctgc aagctttagg ttttggacat ttatctacct atggactgat gaaaaaccaa
    57361 tcgcaaaaag aaacgatgca gttaattgaa tatttgatat cgaatggcta tcttctgacc
    57421 atcaatggtg agtatcctgt tttgaaagta acagaaagag ggatacaagt attgaaagga
    57481 caagaatctg tttatcgaaa ggaacccaag aaagtccagc agctatcgga tgaagaaacc
    57541 gatacactat ttgaagtgct gcgggaactg cgaacggatc tagcatcaga agcaggcgtt
    57601 cccccgtatg tcgtattttc agattccaca ttgaaagaaa tgagccgaat acgtccatca
    57661 agcagattgg agatgcttca gataaaagga gttggccaaa gcaagcttga taaatatggc
    57721 gaagcctttt tatctcggat aaaaaatgcg gactctaacg ttctggataa gtagaaagaa
    57781 cgaatacgta aaaatgaata aaaacaactg gttaaatctg ttttttttgc tccttatgaa
    57841 aatcaaatat gttataatta aggaattaga atgggaggta agcacagatg gattctttgt
    57901 cgaaaaaact tgcgatccaa gtattaaatg atgaagcaga acggatcaaa cgattaatcc
    57961 gaaatcaaaa caacagtctc tgtatctcac aatgcaaagc cttcgaagaa gtggtagata
    58021 cacagatgta cggcttttcc cggcaagtcg gttttgctgt ccgtatagga gtaatcggaa
    58081 agaacgaggg ccagctgatg ttaagtgagc tagaacgaga attgaatcag ttatatagtg
    58141 aggtttacca agaaatttat gataaaaaag aagttggcaa ggaggaatag acttgcctaa
    58201 gaaagtgaaa aaaaggcatc tattagacta tagcatcttg attccctatt taattttatg
    58261 tgtattggga ttgatcatgg tatatagttc tacgtcgtat ctattattag aaaacggaca
    58321 aaatccgtcc gcatcagtca ttaaccagag tattttttgg gtgcttagct tgattgctat
    58381 cgcactactt tataaaatga aaacagatgt tttgaaaaac cagcgtttga tcatggcagc
    58441 catcgcagtt ttgacgattt tgctgctgat tgttgtgttt tttggtaagg agatcaatgg
    58501 ggcgaaaggt tggctgcaaa ttgcaggatt ctcgatccaa cctgccgaat acctaaaaat
    58561 catttctatc tggtacctgt ctctgacttt atctaaaaga caaaacagtg tacaaaaaga
    58621 ttttcttggg actgtgaaac gtccacttgc aatggttatc ggacttactg cattagtcgc
    58681 tattcttccc gattttggta atgcggcagt tatctttttg attattttgg ttctgctttt
    58741 agccagcgga gtcaattatg tgtatacttt gattgtagga gtaggaggct tttgtctaag
    58801 tacttttacg atctggctga tcaatatcac aaacggaaag atcttacccg gacgtttaca
    58861 gtatatctat aatcgatttg ctatttacca aaatcctttc tcagacgaat taaataaagg
    58921 gcatcaacta gtcaacggct actatgccat gttcaacgga ggactatttg gcaggggatt
    58981 aggtaacagt atccagaaaa aaggattttt acaagaagca caaaccgatt ttatttatgc
    59041 aatcgtagtg gaagaactgg gagtgattat ggggattttg atattagcgt tgctattctt
    59101 tatgattgtg cgcattgtcc ttgtaggtat ccgttcaaaa gatccgttca attcgctttt
    59161 gtgcattggg atcggcgcaa tgtttttgat ccaagtattt gtcaatcttg gaggaattac
    59221 tggcgttatt cctttgacag ggatcacgtt cccattttta agtcaaggag gctccagttt
    59281 gctgatgctt tcgatttgtg tcggctttgt cctcaacatc agtgcggatg aaaaacgcaa
    59341 gagcttaggt ttataataaa aaaagatgta ggagtggttc gatgaaaaaa gttttagttg
    59401 ctaacagggg tgaaatcgct gtacgtgtat ttcgtgcttg tacagaatta ggaattaaaa
    59461 ctgttggaat ctatgcagaa gaagatgaat attccgtaca ccgtttcaaa gcggatgaag
    59521 catatttagt aggacaagga aaaaaaccga ttgatgcgta tctagatatt gaagggatca
    59581 tttctatcgc gaaagaatgc ggagctgacg ctattcatcc gggttacggt cttttgtcgg
    59641 aaaacttgaa ttttgcgcaa cggtgcgaag aagaaggcat catttttgtt ggacccaaac
    59701 tgcatcattt agatattttt ggagataaaa tcaaagcaaa agctgcagct atcgaagcgg
    59761 ggattgcttc gattccaggc acagatggac caatcgcttc tatagacgat gccttggagt
    59821 ttgcgaaaca atacggttat ccgattatga tcaaggcagc tctaggcggc ggcggacgcg
    59881 gcatgcgtgt agctcacgat gaaaagagtg caagagaggg ctacgaacgt gcgaaaagcg
    59941 aagcaaaagc agcctttggt agtgatgaag tgtatgttga aaaatacatc gctaatccta
    60001 agcatatcga agtacagatt ctcggggata cgcatggaaa cgtcatccat ctttttgaaa
    60061 gagattgttc tgttcagcgc cgtcaccaaa aagtagtaga agtagcgcct tgtgtctcta
    60121 tgaatgaaca gcaacgtcaa aaaatctgcc aggcagctgt ccaattgatg aaatatgtcg
    60181 ggtatgtcaa cgcaggtaca gtagaatttc ttgttgaagg agatgatttt tactttatcg
    60241 aagtcaaccc tcgcgtccaa gtggaacata cgatcacaga aatgattaca gatattgata
    60301 tcgtaacaac gcaactgttg attgctcaag gtttggatct gcataaagaa atcggattgc
    60361 ctcagcaaga aggaattaaa ttaaatggtt cagccattca atgccgaatc actacagaag
    60421 acccgttgaa taacttttta ccagacacag ggaaaatcga tacgtatcgt tcacctggtg
    60481 gttttggcgt acgtctggat gtcggaaatg cttacgcggg ctatgtagtg acaccgtatt
    60541 ttgattcatt gctagtaaaa gtatgtacgc atggtgctac ctttgaaaca gccattcaga
    60601 aaatggaacg ttgcttgaaa gaatttagaa tccgtggagt gaaaacaaac attccattta
    60661 tgctcaatgt catcacacat cctgaattcc aatcaggaaa tgcaaaaaca accttcattg
    60721 atagtacagc aacattattt gaatttcctc gactacgaga ccgcggaaac aaaacgatga
    60781 aatatatcgg tgaaattact gtgaatggtt ttccaggtat cgaaagtggc gaaaaaccat
    60841 tttatgaaga accacgtatg cctaaagatc taatcacaag aactgattac gtaacggcta
    60901 agaatgtatt agatgcgaag ggtgccgatg ctttggtcga atggatcaaa ggacaggaaa
    60961 atttgttgtt gacggatacg acatttagag acgcccatca aagtctgcta gcaactcgtg
    61021 ttcggacaaa ggatttcaag cagattgcac gtttgactgg agaaggtctt cctgaactct
    61081 tttcaagtga gatgtggggg ggagcaacat ttgatgtggc ttaccgcttt ttgaatgaag
    61141 atccttggca acggttgaga aaaattcgtt ctttaatgcc taatacgttg ctgcaaatgc
    61201 ttttcagagg ttcaaatgcc gttgggtatt ctaattatcc tgacaatgta ttggtggaat
    61261 ttgtcaaaga agcagcagcg caaggaatcg atgtatttcg aatctttgat agtttgaact
    61321 ggactccaca aatggaaaaa agtatccaag ctgtacggga tactggtaaa atcgcagagg
    61381 cagctatttg ctatactggc gatatcaacg atccaagtcg ggcaaaatac aatgttcagt
    61441 attataaaga catggcaaag gaactagaac aactgggtgc gcatatcatt gcaatcaaag
    61501 atatggctgg gctgcttaaa ccgcaggcag cttatcgttt gattagtgaa ttgaaagaaa
    61561 cgacagatct gccaatccat ctgcatactc atgataccag cgggaatgga atcatcactt
    61621 attctgctgc ttcaaaagca ggagtagaca tcgttgacgt ggcaatgagt gcaatgagtg
    61681 ggaatactag tcagcctagc atgagcagct tgtattatgc actggtcaat ggtccacggc
    61741 tgccagaaat cacgattgaa aatgcacaga aattaaacca ttattgggaa gatgtgcgca
    61801 tgtattacaa accgtttgaa aacggcttga atgctcctga aacagaagta tatatgcatg
    61861 aaatgccagg aggacagtat tcgaatctac agcaacaggc aaaagctgtc ggattaggtc
    61921 atcgctggga tgaaatcaaa caaatgtatc atactgtcaa cttgatgttt ggcgatatcg
    61981 ttaaagtaac tccatcatct aaagtagttg gagatatggc actatttatg gtccaaaatg
    62041 atcttacaga agaagatatt tatgaaaaag gcgaaacact aagtttccct gaatctgttg
    62101 tgactttctt ccaaggagaa ctagggcaac ccgttggcgg atttcctaaa aaattgcaaa
    62161 agattattct taaaggcaga cctgcattga atgaacgtcc aggtcttttg gctgaatcag
    62221 tcgacttcaa cgaagtaaaa aaagaattgg cagaaaaaat tggctatgaa ccaaaacaag
    62281 acgaagtatt aagctatttg atgtatccgc aagtcttttt ggactatcaa aaagcatata
    62341 atcaatttgg cgatgttaca ttactggaca caccaacatt tttccaaggt atacgtttgg
    62401 gtgaaacaat caatgtacaa atcgaacgcg gaaaaacgct tatcattcgt ttagatgaaa
    62461 tcggagaacc cgatatcgaa gggaatcgcg tactgttctt caatttgaat ggacaaagac
    62521 gtgaaatcac tatcaaagat aattcgatca tcagtacggt ccaaacccga ttgaaagctg
    62581 aaccgacaaa ccgagaacaa attggagcaa cgatgtctgg ttctgttttg gatgtattag
    62641 tgaaaaaagg cgataacgtt aaaaaaggtg atacgttgat gattactgaa gcgatgaaaa
    62701 tggaaacggc catcgaagca cgttttgacg gagaagtcgc acatgtatat gtgtcttcag
    62761 gagacactat ttcgtctggt gaccttttga ttgaagtgac tgagaaataa taagcgaaag
    62821 gtggggaaac atgaaaagac tgggtttgtt ttggctgatt ctgctattag ttattgtggc
    62881 attctacatg gaaccagtct tgtttccgcc aaaacttgaa gtgaaggaaa actctgatca
    62941 acaaatatca aaccaaatga caacgtggaa ataccaggag cttaaagcaa ctggtttttc
    63001 tacttatatc ggaaaaccga tcgatcagct ggaaaaggat tttggccaag cctatgatcg
    63061 attaactagc ggatttggtt ttgaaacaag atattatgaa aataaagcta gtcatctcac
    63121 atttgaagcg aacatccaag acagcagagt cacaactgtt aaagtactgc aaacagggcc
    63181 tgctgatatc gcgccgtttt atttagggat gacgatgcaa gatcttacga aaatcactac
    63241 tatctatact aatttcactt ttgagtacca tgatacagaa gttggaatcg aactaatgga
    63301 agaggatatg aattatcgtc cgctaattgc ttttgataac gacacttttg ctattttatt
    63361 ttttgatcaa acaacaaacg gcctattttc agttgtgtat ttagataaag atagtctttt
    63421 gaaactattg ccatatcaag tgtttggtga aggccttcca cattatcaag cagataaatc
    63481 ggctgattgg gaatcaatca atcgcgttaa agaacgaaaa agtacgactt tattaaatat
    63541 gcttagaaga gaagacgaac ttcccatata caatcaaaca cttgcctttc aaaaccacag
    63601 tcagctgcta ctacatgatt ttttgacaag gcctgaggaa atattgtcag aggaacgtat
    63661 ggctgattgg caaaaatcgc taggcagtgc tcaaacgaca gtgaaattct cactgacgaa
    63721 tgatgaattg gagaagttaa tcagtaaaca aaaattagaa aatactagtg ggctatttat
    63781 tcatccggcg attgacgcta ctttttcgtt tttatattgg tacagcgatc cttacaacca
    63841 tgaccgtttc atggacccgg gaacggattc tgtaggcatt gctttttcta aagaaaatat
    63901 gttagtctta ttgcaagaag aaaacggaga aagtagtgat agcagtgatc gttaacgaag
    63961 agctgtttca actggaggat caatgcctcc aagtcgctga aatgataaaa aagagtaaaa
    64021 cgatggcttc ttatcttgaa cataaacagt caatggaaga atctgcaaaa gtttgccagt
    64081 tgaaagaagc gttcttgtct aagaaagaag catttgaaaa tgtagcggca tatggtgagt
    64141 atgcacctga ttatcgtgaa aaaaaacgag ctgttcgaaa agcaaaaaga cagcttgata
    64201 tggatgagca tgttgcagct ttccgatata gtgaaacaca gctgcaaagt ctgttggatc
    64261 aaattgtcca agtacttgcc gaagaagttt ctaatgaaat caaagtagat gcaggtagcc
    64321 cgttttttga aacgaaaaaa cactttggat gcggaggtaa ttgtcatgca attagacaat
    64381 agtgaatttg aaataacaaa acgacgcggg ctgatcgtat gggtctacag cttaaaacaa
    64441 ttaaagaatc tgaaaaagtt cggcttgttg cattatgtct caagaagaat gaaatatgtc
    64501 gtgctttact taaatgaaga gacattggaa gaaacagaag aacgaatccg taaattacat
    64561 tttgttcgaa acgtagaacg ttcttaccga ccggatatcg aaatgaattt tgccgaaaaa
    64621 ataggaaaca aaacagtatt aaaagacgaa ggtttcgaaa ttgaagagct aaatacagaa
    64681 atccgattag ctgaacatct ttaaaaatct cttatgagca gtttttaaat aaaaaataac
    64741 ttggataacg atcgattttt gatcattgtc caagtatttt tttggtatac tagtaccagt
    64801 accatttcta aggagtgagt agatgcggat aatatcagga aattatggcg ggcgccgttt
    64861 aaaaagttta gcaggggcga acaccagacc aactacagat aaagtaaaag aatccatatt
    64921 caatatgatt ggaccatatt ttgatggaga gacagtattg gatctgtttg caggaagcgg
    64981 tggtttagct atcgaagcag tatctagagg ctgcagtcat gcggtatgcg tagacaaaaa
    65041 ttaccaagcg ctaaaaatca tcaaagaaaa catcgaaatt acgaaagaac cagagaaatt
    65101 taccacaata aaacttgatg cggacaaagc aatcgaacgg ctagcagcgg agaaacaaca
    65161 attcgactac ttgtttcttg atccgccata tgcaaaacaa aaaataatcg atcaaatcca
    65221 taaaatggaa gaactgggac ttttttctaa aaccgcagtt atcgtatgcg aaacggataa
    65281 aacagtcgaa ttgccagaaa ctgtggctgg attccatcaa ataagaaaac agatttatgg
    65341 cataacggcc gtaactatct atagaaaaga gggaaatcaa tgaaacgtgc attattccca
    65401 ggaagttttg atccttttac aaaaggtcac ttagatacgg tggaacgtgc ggctaaatta
    65461 ttcgatgagg tagtaattgg tgtttttatc aatacttcaa agaaaagttt gtttccccca
    65521 gaagaaagaa tgacattgat cacaaaagct gtttctcatc ttcctaatgt aaaagtcatg
    65581 catcaagaaa atcaattgac ggtagaaaca gcaaaagaga ttggtgcaga tgcgttgatc
    65641 agaggcatac gaagtatcaa agactttgaa tatgaacgag agattgctca gatgaatcat
    65701 catctatatg atgaattgga aactgtcttc ttattagcaa aaccagaata tagtcacgtg
    65761 agttccagta ttttaaaaga agtactgcac tttggcggag atgtgagcag ctacttaccg
    65821 ccagtgatca acgaagcttt agctggaaag cgtgaatcaa atgaaagcta aacaatggtt
    65881 gaaaacagta ctgattatca tatttggaat gttgatcatt ggatttgtag tagttccctt
    65941 gccgtattat gtagaatcac cgggagccac gatcgatctg aaagaactaa ttacggtcaa
    66001 tgataaggaa gataaaggtt ctgggtcttt ctctcttacc tctgttggta tcaggcaagc
    66061 tacaggtttc ttagctttaa aagctaaaat gacccctttt gaagaattga tcagtgaaga
    66121 agaattgact ggtggggcga caaatgaaga atataatcaa atgcaacagt attatatgga
    66181 ttcttcccaa aatgcagcaa tcgaacaagc gttaaaactt gcagacaagc cttataaaat
    66241 ggaattcaaa ggcgtatatg tcatgagtgt agagaaaaca tcgaatttct ttggcaagct
    66301 ttcagttgga gatacagtaa caaaagtaga cgggaaaagc tttcaaagta cagaagcatt
    66361 tatggattat gtaaaaagcc aaaaagttgg acaaacaatc gaaatcagtt atttgcataa
    66421 tggtgaagaa aaaacagctt ctggtgatct gatcgagtta ccaacagata aaaaggcagg
    66481 aataggtatc acgcttactg accataccga gatcgaatca gatacagatg ttcgtattaa
    66541 ttctggctct atcggtgggc catcagcggg attgatgttc actttagaaa tctatgaaca
    66601 agtcactggt aaaaacttgc gacatggtaa gcaaattgca ggaactggaa cgatcaacag
    66661 tgaaggagaa gttggccgaa tcggaggaat cgataaaaaa gtggcaagtg cggataaagc
    66721 tggcgtagag attttctttg caccagatga tacgatttca gacgatgtta agaaagaata
    66781 tcctgaaata aaaaccaact acgaagaagc aaaagctgcc gctaaaaaat tgaattcctc
    66841 aatgaaaatc gtaccagtaa aaacagtaca agaagcgctt gactatctag agaaaatgaa
    66901 atgaaactaa ataattaaag aggggttgtg acacgagttc tgtcacaacc cctctttttc
    66961 gtcaaaaatc ttcacgataa aaataaaaac aaaagaaaaa attgacgtaa ttagatgttg
    67021 aagggacgat tttgccagag ctcactgttt cttcaatttt aaatgaaagg agtaatgaat
    67081 gatttttact ggtcattctt tgaaaaaaga acaatgatag aaaaaatcag caagaaaata
    67141 ctagcttcac ccaaattgat catttggatg tctatgatag ttcttatctt ttgtatcgca
    67201 agtggttttt tattatcaaa tttgctattt tatagagaaa cagaagagac tgctgcaaaa
    67261 gaaatacttt cttcgtttag ttccagtgga gaagatccat cagctgaagg aaacgatgta
    67321 gaagaggatg ctcgtccaaa ggtcatgtac accgatatca aaggaagtgt gaaggagcct
    67381 ggtatctatt ccttttcttc agaagaacgg gtctatgatg tactaaagcg tgcaggtgga
    67441 ttattagaag aagcggatag cgatcgaatc aacttttctg cgaagataga agatcagcaa
    67501 gtcctatata tccctgctgt aggtgaagag ctgccagaac atcttgatca gttggcatcc
    67561 tcggaaggaa aacagcctac agcagattcc gagcctccca aaataaatat caatacagcc
    67621 actccatcag aacttcagca gattcctggg atcggatcag tcaaagcgca agaaatcatt
    67681 cgatttagag aagaaaacgg atccttccag aaagtggaag acctgcagga gatttctggt
    67741 atcggtgaaa agacagttga aaaactaaaa aacttcgtta caattaaata gaatgattca
    67801 aaatcgactg gcacgagcaa taaatggacg ctaatggata ctaagaataa tccaattcta
    67861 agagcttggc aggacgagga ggtagtattt ttggatagga aatagcttga ttgttcgcaa
    67921 agaaacatta aaaaaaccaa tgctgaatgt ctatctccaa aataaaatat ctgggattca
    67981 tattatgaat acggctgtca gcggcaataa cagtcaagct ctacgagaac gctttgccaa
    68041 agatgtactt agctatacag cagataaagt atttattctc attgggacga atgatctagc
    68101 agagcataaa caactttcta aagaaacgta ccaaaaaatc tgcagtggat gatagttcag
    68161 ctgaaaaaag actatagttc tgatcatgct ttctttatca cgccaccagc agtcgatgag
    68221 acaaaacaaa aatatcggaa taacaagttg atcaaagaat atatctctgt tctcacagaa
    68281 gtagcaaaac gccatgattg tgaagtatcg atttttatac ggaatttctt gaacaaatgg
    68341 attcgaagaa tttttataat gggctaatgg atgacggact tcatttcggc agtgaagggt
    68401 aggatctttt gtcagacagg atgattcgtt atatttaaag aatattttgt ttaagcaatg
    68461 agtacttttt aatcaacttg aaaaaacgga ggaatataaa acatgttaga aaaatcttca
    68521 aaagcatgcg atacgaataa agaaaaagtt actgataagt cacataatga acgcattcct
    68581 tgggaccagt actttatggc tcaggcagta ctgttatctt tacgtagtac gtgtacacgt
    68641 ttagaagtag gagcgacact cgttcgagaa aaaaggatca ttgctggcgg ctataatgga
    68701 gcagtcagtg gagatgtcca ctgcatagat gaagggtgtt acgtcgtgga tggacactgc
    68761 ttgcgaacga tccatgcaga gatgaatgca ctcctacagt gtgcaaaact tggtatcccg
    68821 acggaaggtt cagaaatcta tgtcacacat tttccatgtt tggcctgtac aaaggctttg
    68881 ttgcaagctg gtgtgaaagg gatcaattat ctccatgact atcgaaatga tccttatgcc
    68941 caagcgttga tcgaacaatt aggtgtatct gtacaccaag ttgctttaga ctcacagcat
    69001 ttttcaaaac ttcaaaatga attaacagga aaacatgtct agcgttttag aaaggcatgt
    69061 tcgaaatcgg ttgatttttc cggcaattac gtcgatgatt atctgtttgt tgtattacac
    69121 tgacaattgg ggttatcgtt tgcttcttgc cggaattttt ttatggtttt cgctaaaaga
    69181 aggacgtttt atcgcgtact tgtgtatttt gtgtagcata acggtatcca tttcttatag
    69241 gctacaagag tattcatttt tagaggaaaa aacaacatct gcgcaaatta ctgtatttac
    69301 agatacgatt cgtgcaaatg gtaatttttt gacaatggaa ggaaggttat cagagaataa
    69361 acaaaagctc cagctttctt atcaagtaaa cacagaagca gaattgaaaa catggcttaa
    69421 cttccgagga aagggaatag aattgactgc tgaaggcgag ttcatctctc cagcaaaaaa
    69481 gcggaatctt tataattttg accaagaagc ttacttcagg aaccatagaa tttctggacg
    69541 gttccaaatt caaaagattg aacagatcac catgcaaaat cactggcgaa actggcttca
    69601 gagaaaaaga ggatctttta tctcctttgt ccaatctgaa tttccgcaaa aaacaagtgt
    69661 atatattaat tctttattat ggggctataa agatgcagga ttcagagaac cagaagaaat
    69721 ttttagggag agtggtttgc tgcatctgtt cagtctatcg ggtctacaca tccaatttta
    69781 tttagggtgg ctgtattatt tatttcgacg tatcggatgg ccactacacg tcagtattat
    69841 tccgttgagt ctactaacta tctgttatgt ttctattgca ggaagttcta tttctgtttt
    69901 gcgtgctagt ttgctgtttt tattgcgatt gctagtcaaa ttgctgaata agcattattc
    69961 caccatggac ttatttgcag ttgtcttttg gcttctttta ctatttgatc ctcgatttct
    70021 ttttcatgcg ggtggacagc ttagtttttt catgagtttt ttgtttatcc tgatttcttt
    70081 tgatggagat tggttgaaaa aaacggcctc tcacgtcctg tttactatga tcacgatgcc
    70141 gttgattgta tggcattttt atgagtggcc tattttaggt agtcttttta cattactgat
    70201 tgcaccggta ttcaagtttc tttttcttcc tggtgtgtta tttctcacac tcttcaatcg
    70261 ctggctgccg gaaactttac ttttgttgat agaagaggga ttaatcttat ttgagcgaat
    70321 aatcgatttt tcttcagggt cgtctctcat tataggacgt ttgccccttg tgctatctgg
    70381 gatgtatatt ttcggattac tgatttgtat ggataggttg aaagaacaac ctgtgaaaca
    70441 cttgttttat gttggtcttt tttcttttat ttttttgact ttgccatttt tacgcttttc
    70501 ttcaacgatc gcttttatcg atgtcggtca aggagacagt atctttttgc aaagtccttt
    70561 tcgaaaagaa acgattttga tcgatactgg aggtcagtta cactttgaaa gagaaaagtg
    70621 ggcgcaaggt atgatacgtc ctcctgctga aagaaatatc gttccatatc taaaaggtca
    70681 ggggataagt gtaatcgata aactcatctt gacacacgac gatacggatc atgtgggaga
    70741 attacccacg ttatctcagc attttactat caaaaaaatt tatatcggtt ggggcgctgg
    70801 acgaaatgag ccattacaaa ggcatttatc tgaagctcaa aaaaatggta ctgagatcat
    70861 tgaaatcaaa catggggaca ggatcagcgg ttattatgat ctttatgtat tgactccttt
    70921 tgaaaaggga gagggaagaa atgaagattc gattggtcta tggatggaat ataacaatag
    70981 gcgcttttta tttttaggag atttgaatca agcaatggaa aaacaattgc ttttgattta
    71041 tcctaatctg aaagccgatg tagtcaaatt aggtcatcac ggtagccgta cgtcaagtaa
    71101 cacagatttt ctttcccata ttgaagcaaa acatgggatt atatcctgcg gcgtaaataa
    71161 tcgttatggt cacccgcaca gcgaagtatt ggagacacta gaagaaaatc agataaaaac
    71221 atggcgaacg gatcaacaag gaatgatcac ctatcgctgg catccagttt ttcatcctca
    71281 tgggctagtg gaaacaatga tagactagta attctcatct gctcatggta ggataatttt
    71341 tgaaagtggt gagtaatttg agtatacaag cagagttaca aaaaatacgt aaagaaaaac
    71401 ttgcatcttg ttacttgatt ttaggaacag aaaagtttct ccaagatcaa gttcggacag
    71461 aaattgtcaa aaaaatccaa ttagagggcg aagatgactt aaatttttta agttttgaca
    71521 tggaaaatgc aagtttagat gaggtagtag ctgaagcaga gacgttgccg tttttcggag
    71581 atcaacggtt agtattcgta gagaatcctt attttttaac aggtgaaaaa gtaaacaatg
    71641 gaatcgaaca aaatactgat ttattgacgg cttatttgaa agaaccatta gaatcgactg
    71701 tattagtatt ctttgcgcca tatgaaaagt tggatgaacg gaaaaaagta acgaaacaat
    71761 tgaaaaaaac agcaattatc atcaatgtcc aacagttgaa tgaaaaagaa gtacgtcaat
    71821 atctgatgaa taccttagag aattcctcaa tcaaaatgga acgaagtgca attgatttat
    71881 tcttgaggtt gaccgactta gatttatcca aaatgatgag agagttacag aaattggtcc
    71941 tttatggaca aaatcaacag caaatcacgg taagagaagt agaagaatta gttcctaaaa
    72001 cgttagaaca taatattttt gacatgaccc aatatatttt aaaagggaag acggaacaag
    72061 ctttgcgttt atacgaagat ttagttatgc aaggggaaga aacaatcaaa attaatgcga
    72121 ttttgctttc tcaattacgt ttatttttac agacaaaatt tcttgtaaag attggttatc
    72181 agcaggcaaa tattgctgaa acattgaaaa tccatccata tcgtgtaaaa cttgccatgc
    72241 aggaagtaaa aaaattcgat gaacatttgc tggtacagtt gtttgatcaa ttagttgaga
    72301 tggattatca aatcaaaacg ggacaaatcg aaaaagaatt aagttttcaa ctattcgttt
    72361 tgcgcacagg gcagttgtta agaaatcgat aagaagaaag acgagggcaa agcatgcggg
    72421 aaggtcgttt gtttttgtcc tttttttgac aaataaaaaa atcggccgaa gccgattctt
    72481 ttatttagcg atttttttgc ttaaacgaga tttgtcgcgg ttagctttgt ttttgtggat
    72541 tagacctttt gattcagcca tatcaatagc tttaacagct tctttatata acgcatctac
    72601 gttgtcagca cctgaagcta cagcatcttc aaattttttg attgcagtac gcatagcgct
    72661 tgtttgagat gaatttttca cattagcgtt ttcgcttgta cgaacacgtt tgattgcaga
    72721 ttcaatgttt ggcattagtt tcacctccga taacttaagt tcttacgcgt gttaccgcat
    72781 aattcaacat tcattattat acctaaaggc agcgtgcttt gcaatatgaa catgacaagt
    72841 ttttttcctt aacagtcttt tattaggatt ttttttcagt aaaaacggat agtacaagct
    72901 gaaaaaaatc aaaaagacgc tattgtggga ggcaatagcg tcaaaccaaa ctagattttt
    72961 atttatctat ttaaacaaag tttgaatggg aatgtttggt actaagttat tatataacaa
    73021 agagaaccgt ttgcaaagtt ttttttgaaa agggatacga ttccctgttg ttctttgttt
    73081 ttctattaag aaactgcagt tattttataa ccagtatcct ttgatcagta aaggctattc
    73141 tggtgtaccg attattttaa tgtattcatc gatatttttt atcaacattt tttttatgac
    73201 caactggttc cgacggttcc atttgccact tacttccagc acatatttat ttaggggcaa
    73261 acgtaagata tattttgcca aatagcgatc tttaagcagg ccattgatca cacggtcctc
    73321 aagctgcaag ttgatcccag tcagcatcat tggctgttct tgtaaaacgt acgtatcaat
    73381 taaaagacct tcaaaagttt ccacaagcgt cttcctttct tttcaaagta acctgaaaac
    73441 aggcactaat tcttccattt tgatattcgt tgaagtggat gcgatcattc tttcttttgt
    73501 ccactgtaat ctagtataac aaaaaagagc agaagagcca aaaagaaaaa agagcatcga
    73561 attctatagg aagtctcatt ggcacggcct aaattattac aaaacattga ttaaaaaaag
    73621 cccctgcatc gcaggagcat cccctatatc gttttaatag gtcaatcaaa aagcagtatc
    73681 aaacacattt tgtatcaaat caggaaataa tagataagct aagcccagaa tcaaaagtac
    73741 cgctagaaga aaccagccga ttgttcctat gaaatacttt aatttttcga acattgtatc
    73801 acctcgttgt cagtatatca cggatcagta aattgggggt gttaagaatc tcctaaaata
    73861 gacaaaattt gttctatttt cctaaagcaa atacttgtaa gatacagtaa gtgataccag
    73921 aagcaatgac cggtccggcg gcgattcctc ttaagaagac aacacctaaa atcgtgccga
    73981 aaacaagtgc aacagtgatt tgtggatcag aagcaatcaa tcctacaccc ttggaagata
    74041 agacagccac tagcccaccg caaaaaacag ctacccagcc aataggggat ttaaaggctt
    74101 ctaatagatc acgtagaccg atttctcctg ttgcgatagg gattagaata gccgctgtga
    74161 tgatcgtcac cccaatattg attcctttgc cttgaagcca agggaaaaag gaacgggagg
    74221 ctggtatgag cttcataatc aaaacaaaag ctgccgctat catcagactt tgatttttag
    74281 ctaaaattgc tacaagtaaa ataattccta aaaaaagcca actttccatg aaatatattc
    74341 ctcactttct tcgaaacaat cataacatgt ttttagaaag ttacaaaagt aggaattcat
    74401 ccttcaagac ctattcataa gctgtttttt tcataaaata aacaaaatca taaaaaaaca
    74461 ctttgcttat ttgacagaag acagccgcgc tttgtatagt ggacaagact tacatttttt
    74521 tgaagaatca gaaagatcag gtaaaggtct tagtaaacgc aagccattca gaataaccaa
    74581 tattgtgctt ccttcgtgtc ctacaactcc aagaggtaga tttaaaaatt gcaggaagtt
    74641 agaagcaatc aacaagagaa taacaagaat cgaaaaaata atattttgtt tgatgatccg
    74701 ccgcattttt aaagatagcc gatgactgta gacaaattta tttaagtcgc ttttcattaa
    74761 gacgatgtct gcgatatcca tagcggcatc tgtcccttgc cccatagcga cacctaaaga
    74821 agcggctgct aaagcaggcg catcattgac tccatcacca accatcgcat ttacttggta
    74881 aagttcattc tcttttttga ctagttgtgt tttttcttcc ggagtacagc ttgcatagta
    74941 atgttcaatc cctacttgtt cagcaatggc ctttgctgtg ccagaatggt cgccggttat
    75001 catacttgta tggatgtttt gggatttaaa gtaggaaatt acttgttggg tatttgcttt
    75061 tggaatatct agcagaccta aaacagcaat taactgctga tctttagaaa gataaatcac
    75121 ggttttgcct tgattttcca aacgttcgat catttccgca atctctttgc tgattatcat
    75181 cgtctcagga tcatatgcgt gcttgccaac tttccattgc gcacctaaat aggtagtttg
    75241 taatccaaaa ccagtaattt cttctattgg taagtattgg atttcttcag gtattgtgca
    75301 atcgaaatat tgcaaaatcg catgagcaag tggatgcgtc gttttttgtt ccatagcaac
    75361 aagaagttgt tgtgccaaat ccttttcatc aaagaaaaag ctgtcagtta caactggttt
    75421 tcctttagtg agcgttcctg ttttatcaaa ggcaatcgct tttaattcag aaagcttttc
    75481 taaatggata ccgcctttga ttagaatccc attttttgca gaatttgaaa gagcagctag
    75541 agaagctggt gtagcagatg cgacaagcgc acaaggagaa gccacaacta ataataccat
    75601 tcctcgataa aagctttcat cccaactcca acctaggaaa aagtggggga gaaggatcat
    75661 tagaggaaca gcaagcaaaa tcaattttac ataattattt tcgattcgtt cgataaatga
    75721 agctgtttga gttggcgtat tctgcgcttc ttctactaat tggataatct tagcaaagac
    75781 agtttcggaa ctcgtttttg ttactcgaat cgtgatggga tttccttgat tcagcgttcc
    75841 tgcatacatc tcatcgccta aatatttttc tacaggcaca gattcaccgc ttaatgcaga
    75901 ctcatcgatc gttgcctgtg tgctttctaa aaagccatct atcggaacag ctgctccttt
    75961 agcgacaaat accaagttat ccacctttag ttgagaaaca tctacttctt gcatttgtcc
    76021 attttctttt aataattggg ctttttgtgg ttgaagattc atcaaagcag taatttcttt
    76081 ttgactttta ttagttgtgt attcctctaa tgcaccgctt aaacaaaaga tgaatgtcaa
    76141 cattgctcct tcaaagtaat taccgatcaa acaggcacca atagcagcta aagccatcaa
    76201 taaatccaca ttcagtgtcc gatcattcca caattctttc aagccttccg atgtttgttt
    76261 atatccaccg atgataatgg cactgatata aaaaagtggg gtgatggtaa gagagaatcg
    76321 gtcgaagata aaaccgaaga tcataaataa aaggcagccg attgttgctg caaaagcttt
    76381 tttctgatta gtcatcgtta ttagacctcc ttgtcaaaac aaggatagca taataaaaat
    76441 gtaattgata ataataacag ctaaatgaga acgataatgg ttatcatttg gtgattaagc
    76501 ttgatgttgt ttttattatt tataatgatt attattaaag aaaataaaaa accagaacat
    76561 ttctcaaata agagaagtgt tctggttttt tctacattgc aataaaccaa taaccaatca
    76621 aaatgatacc aaggataata cgataccagc caaaagcggt aaagtcgttt ttcttcaaat
    76681 agcttagtaa gaatttgata gctaagacgg aaaccacaaa agatacgaat gttcctacaa
    76741 gaagaacaac agtttcttcc attttgaatg aattcccttc agctaaatat ttgacgatct
    76801 tcaagccgct tgcgccaaac atgacaggaa tccctaagaa aaatgaaaac tctgtagcga
    76861 caaaacgcga agcaccaatc aagatagatc ctaggatcgt tgcgccagaa cgggatgttc
    76921 cgggaacaag tgccaagact tggaataacc caacaagaag agctgcttgg tacgtaaagt
    76981 cattcagaga agtccaacga ggtgttttgt ttttgttgcg tttttcgaca ataataaagg
    77041 caataccgta aacgatcaaa acaatggcaa ctggtaagaa cttgtggaaa tttgcttcta
    77101 accaatcatc caaaggcaaa ccaatgatga tggctggtat gcaagcaacg atcactttaa
    77161 accaaagtgt ccacgtatct tttttttcta ccgttgattt acttggagaa aatgggttta
    77221 acttgtgaaa ataaagaacg acgacagcca agatcgcccc taattggata acgacattga
    77281 acatcgacat aaattgtgaa ctggcatcca gtttgatgaa ttcatctgct aggatcaaat
    77341 gaccagtact actgatgggc agccattccg ttattccttc aataataccg agaatcactg
    77401 ctttgataat atttgcaaaa aacataaatt ccttccttcc caattaagat acatcttata
    77461 gtataccgtt attttttgag aaacccaatc tgttttttaa tattaagaaa aacttgagaa
    77521 ataaagcaga taagtacacg aagagaaaaa agaagacaaa gccctcgttc agactttgcc
    77581 ttttatgatt ctctggtaaa aattaaaata tccccattat agaaacgagt cgcgactatg
    77641 tgttttcccg ttatcgatat aagacgtatc attgatgccg tggatagaaa atcgaccgtt
    77701 tgcataagtg acctttgtta cgctgccatt taaaagccca gcacgaacag gctgtttagg
    77761 atcgatcaga ttaagcaaaa aggcgatcgt caaaccatga gatacgacta aaacatttcc
    77821 accaccattt ttttcgcagt gatgggcgat atcttcaaat cctgtccata cacggtctcg
    77881 caatgtttca taagtttccg cccacccagc ggtatctaag ttgtatacag cattagcaat
    77941 ttgttcaaaa gaaacttctg tggtaaacat ttcatcatat gttttaaaat tcaatacacg
    78001 agggatcaca ccccacattt ccatgtcata tccaccttca agagacccga aacaccattc
    78061 tctaatcctt ttttcaataa aataaggaat ttcttttccc ttagaatgtt ctcctagaat
    78121 aatacgggca gtttcgattg cacgaccact gtcactagaa taagcaaatg aaaagtcgac
    78181 attttttaac ccgcgaccta aataatgaat gccttcttgt ccttgctttg tgaggggtgt
    78241 atcacaccag ccttgtactc gttcaattgt attgaacatc gtttttccgt gtcgtacgat
    78301 ataaagtgta gtttctgtca ttttattctc ctcctaagtc gttttaacga ttgaaaaaag
    78361 gatttgtcct tttttcctgt tcaatcgtcg ttgcatcgcc atgtcctgga tagactgcaa
    78421 attcatcagg taatacaaac agctgggtcc gaatactatg aagtaattgt tctaaattcc
    78481 ctgtatacag atcggttcta ccgatacttc ctctaaacag ggcgtcgcca gaaacgacaa
    78541 aatcatcaaa aataaagctg acgcttccta tagaatgccc tggggtaggg acgacgcgaa
    78601 aagacatgtt tcctaaagta taagttttca tttcaaattc atattctgca ggcgagacaa
    78661 taacatcagc aatatcatca tgtctaccga gtccagaaag attcaaaatc ggatcaccta
    78721 gccatttttg ctctagtggg ctgacataaa ctgggatttg ataatacgcg cgtaaaggtt
    78781 ccactgcacc gatatgatcg tagtgagtat gggtaagcaa aatcgctacc ggctgttggt
    78841 ttgttttttt gatttcttgt ttgattcgtt ccgcatcttc tccagggtca atgatcaaaa
    78901 gtgcttcttc gttgtagacc aaataacagt tttcttcaat cattcctgtt tttaatcttt
    78961 cgatatgcat gtgcattcct ccttgatagc caaaacttct ttcatccatt agtataacgc
    79021 attcattgct aggaaacaaa aacaggtact tatttctctt tacttatctg aattatcaga
    79081 ctatatgaaa agtatttgga tattctaaag agaaggaaag taagttttca tagcatttta
    79141 atatgtcctt gttacattag attcatccaa aaatccaaat tctatatcct atatccctgc
    79201 ctaatcagca gggtgttttt ttatgtttgg aaagagagct ctttttgcta aactaggttt
    79261 tttcaggtaa tcttagagag aaagaggtgg tggaaatgat caaacagtca aaaatatctg
    79321 tgcggcactt agtagaattt attttgcgac gtggaagtat cgacaatcgt aaaaaaagta
    79381 accatactgc attagaagga gcgagaatcc accgcaagct ccaaaaagat gcgggagaaa
    79441 actatgaaaa agaagtcttt ttaaaaacaa cagttcaatt agatgaatat tacctgatcg
    79501 ttgaaggccg tgcagacggt attttcaaaa gagacggtat ttattatata gatgaaatca
    79561 aaacctccga accacgattt gaagatttag aaccagaaca agtggaactt ttctttcatc
    79621 aagcaagggt gtatgcctat atctatagtc aagaacatga tttacaagaa ataaatctgc
    79681 aattgactta cttccagacg gcagaagaag tgatcacgag aaaggttgaa catcagacaa
    79741 gagagcagtt agaaactttt tttaaaaagc tgactgaaga ttataaagaa tggcttgttt
    79801 ttcaagaaaa ctggcgcact gtacgcaatg cctctttgat ggctttgaaa ttcccccatg
    79861 atgagtatag gaaaggtcag cgtgaactag cggtagctgc ttataaaacg atccgtacga
    79921 aacagaaatt gtttgtagaa gcacctaccg gaacaggaaa aacaatctct acgttattcc
    79981 ccgctttgaa agctgtaggg gaagaagagg gagaaaagat cttttatcta acggctaaaa
    80041 caataactag acaagtagct gaagatgcta tgacagcatt aaaagataca ggagctgaag
    80101 taaaaagtgt cactttgacg gcgaaagaca agatctgctt tttagatgag acgacctgta
    80161 atccagatca gtgcccatat gccaatggtt attacaatcg gattaatgaa ggtttatggg
    80221 atcttttgaa tcatgagaat cagatcactc gtgaagtcat cgaaacttat gcaagaaagc
    80281 atacactttg tcctttcgaa ctatcattag atgtcagtat ctggtgtgac gtaatcattg
    80341 gggattacaa ttatttattt gatccaactg tttatttaag acgttttttt gaagatgaaa
    80401 aaaacgagga ctatctgttt ttgattgacg aagcacataa tttggtgaat cgttcccgag
    80461 agatgtattc ggcagaacta tcttatgaaa aaacgaaacg aagtaaggaa gctataccaa
    80521 aggaattcaa aaaacttcat cgccgtttca acaaactatt aaaagaattt gattcgatcc
    80581 gagaaatagc aaaagaagat cattgggatt atcatcatca aaaagcaccg gctgaatctt
    80641 tagtaaaggc aggttatcaa ttaagcgaaa aaattaaaga atggctggca gaatttcctg
    80701 agcacccatc acaagaacaa ttgcttcctt attattttga tttgcttcat tttttgaagg
    80761 tcagtgaatt ttatgatgat cactacgaaa caacagtcga aaaaacgtat cgcgatctga
    80821 tagtaaaaga gttttgtatt gatccaagct tgtttcttga gcagtcgttg gataaaggaa
    80881 aaagcagtat tcttttttct gctagttttt caccactctc ttattatcag gaaacactgg
    80941 ggggacaaaa aagtctggct tacaaactgc cgagtccttt cccagaagga aaccagcaag
    81001 ttttcatcgc aaattaccta gagacgactt atcgaaaaag ggaacacagt ctggcaaaat
    81061 tagtagagac gattcatgct tttgctgatg gaaaggtcgg gaattatttc gttttctttc
    81121 cttcttatca atatttagat cttgcggtgg aagcattcag acagcaatat cccgacagca
    81181 atgtgctaat ccaagaaacg gacatgaatg aggaagaacg cgaacgattt ttaacaaaat
    81241 ttcaaacaaa tcccgctgaa acattgattg gattttgcgt acttggcggg attttttcag
    81301 aaggaatcga tttgagaggg gaccgattga tcggcagtat gatcgtaggt gtaggtttgc
    81361 cgcagatgaa tcatgagcag gaactgatca aatcatatta tgatgagaag gaacaccttg
    81421 gatttgctta cgcttatcag cttcctggaa tgaacaaagt cttgcaagct ggtggtcgag
    81481 tgattcgtgg catggcggat caaggaatcg ttgtattggc agatcaacga ttttctagtt
    81541 tttcttatcg acgtttattc ccacaacatt ggcaaacagc aagagaagta cgaagtgttg
    81601 gggaattgga agaaggaata cagcgttttt ggttatcaaa agaagcagta aatcaaaaaa
    81661 acgaggaatg acagacgtca gcctcgtttt ttgattaacg atagttagtg aattgcaact
    81721 cgattggtaa gtcaagttta cgtaataaag caatcacagc ttgtagatca tcacggttct
    81781 tacctgtcac tctaatctga tcttcttgga tttgtgcttt tactttcagt ttttcatttt
    81841 tgatagctgt agtgattttc ttcgcgtttt cacgatcgat tccgttgacc aaatcggcag
    81901 tttgtcgagc tttgccacct agagcgtgtt ctgattcgga aaaatggata tttttgattg
    81961 gcacatttct tttgatcagc ttaccaaata atacatcttt gatctgttcg attttgaaat
    82021 catcatcgct caatacaact agattgctgt tctctaattt gatttctact gtagaatcct
    82081 tgaagtcaaa gcgattggac aattcttttg ttgtttgctg aatcgcattt tttacttctt
    82141 ctgtattgac ttctgataca atgtcgaagc tagcatcttt tgccatagga accctcctga
    82201 tatacatata aatatttacc atacatctat cttatcatag gattagggca gattcttacc
    82261 tgtttgctaa aattcttctc atttgagttc gaagtatttt attttaatag ataaactgtt
    82321 attcttacat ttggaatacc aaagtagggg agaggtgctt gtgagtaaaa ttatgactgc
    82381 gtatcataaa aatgaaagat taaagaaaat agtggttatt ttgataaccg gattgaccgc
    82441 tgcggtcgct ttaaattatt ttttgattcc agccaatgtc ttttctgcag ggatgaatgg
    82501 gatcgctcaa atcatttcct cgcttttata tgaatggttt catatcaaga tagacacagg
    82561 aacatttatt tttcttttga atatccctgt gtttgtatta gggtttctca aagtaggaaa
    82621 acgagcaacg atccttagtt ttgtgaatgt tgtatgtgta tcggtgatga cgatgctgct
    82681 tccagtcgga cagatcactg ataatatttt gatgaatgcc ctagtaggcg gtgttttatt
    82741 aggtcttggc gtaggattat ctttaaaaat gggctttaca actggtggga tggatatcat
    82801 ctctcttgta ctttcacaaa caactggaaa aacagtcgga aactacatgc tgattctaaa
    82861 tggtatcatt gtagtcatcg caggcttctt ctttaactgg gaaagtgcct tgtatacgat
    82921 tatttccatt tatgcaatga ctcaagtaat tgatgccatc cacacgagtc atcaaaaagt
    82981 aacagcaatg atcgttaccg tcaagccaga agaggtaaca gaagaactag caaaacggat
    83041 ggtacgtgga atgacattac tgccgtctgt cggtggctat tcaaaaaaac aagggaacat
    83101 gatcatgatg gtcatcaccc gctacgaaat gtatgatctt gatcagatcg ttcatgaaat
    83161 cgacgacgat gcatttatca atattttacc aactcattca gtatttggcc ggtttgcaaa
    83221 tgaaaacgaa caaaaaatgt atcgaacaac tggcgtattg ccagaaataa aaaatcgttc
    83281 acaaaaaaaa tgaggaatca ggtttatttt agaataaatt taatctatta catctaataa
    83341 gaacattttt ataaatttaa acgagaatct tacttctaaa ttctcattta caagcagcta
    83401 aaaaaagagt atgataaata aaaatcgtgt taaggagtgt cgtacgatga gcgaagcaaa
    83461 ccaagaacgg tctggacaag aaatagaact aatcaaagaa cgtattcttg ctgccttgga
    83521 aatggtgatt gatcctgaat taggaatcga catcgtcaat ttaggcttga tttatgatat
    83581 agaattcaat cctgaaaatg gagaaacagt cattaagatg actctaacaa ctatgggctg
    83641 tccattagca gatattttaa cagaatctat ccatgacgca ttaaaagaag tgccagaagt
    83701 aacgaaagca gaagtcaaac tagtctggta tccagcatgg acgacagata agatgagccg
    83761 ttatgcacgg attgcgttgg ggatacgata gaaatcttgg ctgactagct atgagaagca
    83821 aataggaaaa acaaaaaagc cttttatcct ttctagaaga aaagagataa aaggtttctt
    83881 tgtttataaa attttgtctg ctatattata agttaattaa ataaatgtgt tctattgata
    83941 aaggacattc aaatcccttt ccttttggaa tccttctttt ttacatcagt ttgattttcg
    84001 tatagtattc tttctcatct tcacgataaa tcgcagcccc atttttttgt tgtgctttaa
    84061 gactgccaag atttttttta tttacagaca aaagtgcctc atcaatgccg attttttttg
    84121 cctcttgtag tactaatgct aatccttgtg tggcatatcc ttttttacga taattagggg
    84181 agatgccgta accaatatgg ccagcgccgt ttcttaatgt ttcgttcagt ttatggcgca
    84241 aattaaaaat tcctacatac tcatgttcat cactttctaa aataaagacg gttgcgggaa
    84301 cgtaactctc aggaagatcg attcctaaag acgttttttc gcattttttt acataatcta
    84361 aaaattcagc aaatgtatag ccataagcat tgttgataaa tccactctca tttggtccaa
    84421 agctagtttg tagctgataa gctttcttta aatctgcttc ccatagtttg atcagtttca
    84481 tcgtattcac ctctttaagt aaccttattc atttgttttc tactatagca ctattgttgt
    84541 aaatagccat gcctattttt atttattgtg tcatatcgta ttaagaatca tcgaacaata
    84601 caaatatgaa ttacaataaa aaaattattt gaagttcgtt cattcgttac ttatgatctc
    84661 tagaagaaag aaaacgtgaa ttacttcagc gtctagaatt ccagaaggat agtaatcaac
    84721 agaagaaata atcaatatcc aaatgaaaga agatagctga atcgagaaaa agaggaaaaa
    84781 agaaatgaag aaaaaaataa aatagttact aatcccagag tcgttcgttt aacattgaaa
    84841 tcgatcatat ggataaaaca gattttttca ccaaccctca atagatgatg gagttgctcg
    84901 gatgaattat ttgtgtagat ggcataaggg agggcgtaca gaaatgaaaa agaacaaaaa
    84961 tatgttcttg acaaaaaaca catgtaatcc taaactaaaa gatgtgatgc ggctatggcg
    85021 gaattggcag acgcgctagc ttcaggcgct agtgagggtg acctcgtgga agttcgagtc
    85081 ttcttagccg cataatttgt ttttttataa agagaaggta cacctggagc gatgagaaag
    85141 aaaataacat attatctaaa agaatatagg aaaaatttta aacaacggaa ccagattcaa
    85201 ataaatcaaa aaaaatttgt gtgaaggtgg gacagtttaa aacctaatag attgattcaa
    85261 atagtagatt tatagattct gatacaagaa atactggcaa acgatagtta aggaataaag
    85321 actaaactta aactcaaaaa gaggtcatgc gaaagaataa atcgcatgac ctcttactat
    85381 attttgaatg tgtttaaacg ttcaaataat gaatcttagt accaaccgtt tgcttcccag
    85441 aatgctttcg ccgcttccca agaaccataa cgtgaagtaa catattgttc tgctactctt
    85501 tcttggtttg cagcagagta gtcaccattt aagtaagaag aatctaattg gtaacggccg
    85561 atgtaacgtc cgttcgttgc tgtgtaagaa ccgcttgatt ctttttgtgc gatccattct
    85621 tttgcagagc ttgtacttgc tggagtagca gcagtttctg ttacagcagg agcaggttgt
    85681 gtttcagcaa caggcgctgc ttgtgtttcc gtttgaaccg tttcttgtac aacaggttgt
    85741 tcagcttgaa caggttcagc ttggactggt gcttcttgaa cggctgcttg aggttcagca
    85801 gctgcttgtg cagagccttc tgttgggatt gttaattgtt gtcctgagta gatcaggtta
    85861 atatcagaaa ttgaatttga ttctgcaatg gcattgatca aggagttatc accaacgtat
    85921 ttttgagaaa tcgttgatag agtatcacct gattgaacgg tataagcttc gtccgcatga
    85981 gcagtcgttc ccatgaagaa tgcagcgccg gcagccaaag ttgttccaaa aagtaaagtt
    86041 ttaagtgatg tcatgaaaaa tctcctttat tcgttaaaaa gttttatttg ttgtgttcaa
    86101 cgaggaatac tttaacacgt gaaaatattt cataggtaaa agaagcatga caatttatga
    86161 caaatccacg ttttttgtaa cagaatgatg ttcgctcgat gtgaaaaatg atgaggaatt
    86221 tcacataatg cagaaataat gggattagaa caggtgttct gatgagaaaa gaaatgtata
    86281 aataacttga aagaaattgc ttttgttcat cattttattt acatattgcg tatatttttt
    86341 gtatttttgc ttgagatgtt acaataaaag aaaaaggagg cggttccaat gagtaaaaga
    86401 taccagaaca tcatggtagc agttgacgga tcaagacaat cgatcaaagc gttcgctgaa
    86461 gcccttgact tagcaaagga caatgaagcc cacttattta tcgtgtcaat catcaacaaa
    86521 gttgagctga cccatagtgc ctatgccttt tcaaaaatct atgcagatga aaaacaaaga
    86581 acagaagtag ccatgctgaa aaaaatcaat gatgccaaag agtacggcat tgctgagatc
    86641 cacgcaatag ttgaaactgg agatccaaga aatttgattg ccaatgtcat ccctggacaa
    86701 gaaaatattg atttgatcgt tatgggagcg acaggaaaag gtgctataca acaagcatta
    86761 gttggatcga ccgcttctta tgtcgtatca catgcccctt gcagtgtgtt ggtcgtgaag
    86821 taatgagata agggaggaat agaaaatggt tcgtcctcaa gaagtccgtg cgccaaaaga
    86881 aaaaatagaa attttagcaa ttattgaaga cggcacacaa acaaagaagg gatactcgat
    86941 cgctttagta aagtggaaag gaaaaaaagg tgttgctctg agatgggatg gagataacca
    87001 acaagataaa ggattccctg tcacagctaa cggttatcat ccagcgtggt ttgttctgcc
    87061 tgataaattt atggaattat acagctatga ttatgcaaga gccgcagcat caatcaaagc
    87121 attagataaa ttaacagaag agcagaatga aatggaggaa aaataaaaaa gacgaaccaa
    87181 tcagccttta gaaaactgat tagttcgagg agtaaaaatg aaaaaaggtt atttgggatg
    87241 aaactagaat aatgcgtata acttaaataa aacttaaagc aataaaatgg caagagggtg
    87301 aggcaaatgg aagcaggaaa agtattacag gaagtaaaag cactatgtgc agataaaaaa
    87361 tatgaagaag cgaaaagcct gatcgaaaag aacaaagaaa atttggaaga aaagtacccg
    87421 atcgcacaag aatttataga attaaaacaa ggaacgatcc ttcaccgatt caaacatttt
    87481 tttggtataa cagaatagaa aaaacgatta aagatcggca gaaatttgct gcatctttaa
    87541 tcgttttctt tttaaacatg cgagggattc aattctgatt cttatataaa aaatagatcc
    87601 aaataataag aaaaattact gaaagcgtca attcgatgat gtgtgttatt aatacagacg
    87661 ttgtttccca atgcctaaaa gaaaaaattt gataagtaaa atatacagca ggtaaagagg
    87721 ccagtaaaac tgaaaacttc ttttttgtcc attttatgta atagaaaaga atgcttatca
    87781 taataaaaaa aggaatataa aaaacaaatt gaccgatcgc gatcatacta ttgcctccga
    87841 taaataaagt ccatgataca aaataacact ttgtgcgaaa tggcgcaagc agttttgtgg
    87901 atttatccgg taaaatctgt atcgattttg aaattagagg agaaacttgc tataatcaaa
    87961 gtgaaagaag gagtgggatt ttcatggatc atgtagtgtt agaaatcgat ttgcatttga
    88021 tcaataatat tcgggtgatt tactatgttg taagtaacag tgtcgaacaa cgtgtactga
    88081 cgaataaaat aaatggtatt ttagcaaaga aagacgttca ccgattcaat aatggtgaag
    88141 gaagttatta tagtatccca gtagaaaaaa ttatttatac gacagtcaaa gtcagagaag
    88201 atctagatac caaaaaagca tatgaaccta tttttacaac ttattgattg acagcagatg
    88261 gaggaaaaaa atgaatccat atgaacaact tattcaagat ttgatcgatg gaaaaatcga
    88321 aaagattgat gtaaaaagag aagaattaat ggcttttcga gaagcgtggc tgaagttgga
    88381 gaatcgtaaa tatgtggtgg gaaaagcctc actgaacggc aatgtgactt atcattacga
    88441 tccgacacgt ttattttagt atgaagtatt cagaaaagaa ccaaaggagg acgatgcagc
    88501 agcattgtcc tcctttgatt ttacaaaagt gaaagtttta cttatttgaa tagattttta
    88561 aatttgtttt tgacactgtc gatatttaca tcttttaaaa gattttgggc tttctcttta
    88621 taaggtccta attgttcttt atgttcttcg ataaatcgtt ttgcgccatc gaaattgccg
    88681 ttcttaatca tttccttgac tttttgaaat aattcttctt gattcatttt gaacacatcc
    88741 tttgctatca acatgatttt ttacatggac aaaacgagaa aaactgattt atccacacgt
    88801 caataatatc aaataacgat catttttact aaaaaaacac tcgattctcg cttctaaagt
    88861 aggagaaaaa tctccaactt gggacggatg gaatttcttt aactgaccca tatactgaat
    88921 atataacaag gaggtagaaa gatgaaagtg attaaatatt tgattggact ggcggcgatt
    88981 agtggtattt tgctatttgg actgaaatat tatactgaag gaagttatgg agaaatccct
    89041 ggtatacttg atcagctaaa tccattagtt gaaaaaggag aggtctatgt aaagacacaa
    89101 aaaccagagg aagtaaatga atatggtaca gcaaggtatg tgcagaaagc tgctgatgcc
    89161 aatgggaaag aacgaacggt tgaatttaat ggtctttctg tgttaaaaga aaatcattat
    89221 ttgaaaatta gcaataaagg agcacacata gaaacgtatg aggaagttcc tagagaaaaa
    89281 gttccggaga aagcattagc aattattggg taaatcagtt tttgtattaa gaatacgccc
    89341 gattttatta ttcataattt aattatgtaa actaaataca agtagtaaaa ataatacaat
    89401 aatccccctg caaaaagatt gttcttttac agggggttca ttttttcagc aagcacatca
    89461 aattgggatg gcagggttcg aacctacaat tgcttgattc agagtcaagt gccttaccag
    89521 tttggctaca tcccatttat tcaacaaaat aatcatagca ctttcctaaa aaaacgcaag
    89581 ttatttttct tgatcggata gttgttgctt tactcgtaaa aggcggcgta ctagtttctt
    89641 ttctaatcca gcaggaaggg caatcagttc tgctactgac aagacggtgt ccaataactg
    89701 atattctttg acaggttcat tcataatatg atagatgttt gctaaacgtt caatatattc
    89761 aaagcgagta tactctgttc gagcaattag aaatttcaat aaatcggtgg ctttctcgta
    89821 ctcttgatct gcgtaataaa caagagattg acgatacaat ttgatttcca gttcattgag
    89881 ggtagcaggt ctgcgacgct cgttccactc attaatagag actttacctt gaacatttcc
    89941 cttgcagtca cggacaaaaa taatcggaat ttcatttgga tccatttttt tatgtgtgaa
    90001 tttttccatt atctacgctc ccttcaaagg tttggtatct tgagtataag ggatttttgt
    90061 ttgaattact agcttttctc caaagttagc atctgtccac ccattgcagt gaaaatcgcc
    90121 gaaaaatcgt tgatcggtac tgctcgattt tttacaccat agggatcgtt gacataaata
    90181 ttttctttgt catatccagt gactacacaa gcatgaacaa gaggagtgac tcttacttct
    90241 ccattatttg tggtccaagt cataaaatca gtttcatctg ggacttcaaa attgatagtc
    90301 acagaagtcc agacaggatt tcctttagat agtgcttttt tgatatcatc gagttgagca
    90361 tcggtttttg gaaaagtgtg ataatccgtt tggacgattt gctgagcaag ggaggcaact
    90421 gggggaacat agacgaccat agcccagtct ccgccactga tatcaccaac aaatccttca
    90481 ttaggatcgc catgagtccc atctgcattg aaaacaggga cgtaatccaa ttgctcagct
    90541 aactggtttt tagttgtttc ataaccataa aaagataaaa gcatagaaag cgaagtgact
    90601 tcacagccat tttctaaaga aggagaatca aactggctct ctaatggaac atctagtaaa
    90661 acttctgctt tctcttttgt ctttttcgtt ttttgtgttg aacttttttg tgcagtgttc
    90721 attgtatgtt ctggagaatg gatatgtagg taataacttg taccgcttaa taaaagagca
    90781 gctgtgcccc ctagaaacaa tagttttttg aacgtttttt tcttcatttg aaatctccct
    90841 tttcagctgt ttatctttcc tattataaat gtatttttat tggaaatgga agtattata
//
LOCUS       DAJSMK010000002        87081 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.002, whole genome shotgun sequence.
ACCESSION   DAJSMK010000002 DAJSMK010000000
VERSION     DAJSMK010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 87081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.002"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(550..2163)
                     /locus_tag="ON488_000092"
     CDS             complement(550..2163)
                     /locus_tag="ON488_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCR3230317.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2304..3212)
                     /locus_tag="ON488_000093"
     CDS             complement(2304..3212)
                     /locus_tag="ON488_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3230318.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3395..4519
                     /locus_tag="ON488_000094"
     CDS             3395..4519
                     /locus_tag="ON488_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCR3230319.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4544..4723
                     /locus_tag="ON488_000095"
     CDS             4544..4723
                     /locus_tag="ON488_000095"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230320.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            4746..5663
                     /locus_tag="ON488_000096"
     CDS             4746..5663
                     /locus_tag="ON488_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3230321.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5656..6489
                     /locus_tag="ON488_000097"
     CDS             5656..6489
                     /locus_tag="ON488_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3230322.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6572..7690
                     /locus_tag="ON488_000098"
     CDS             6572..7690
                     /locus_tag="ON488_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCR3230323.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7684..9582
                     /locus_tag="ON488_000099"
     CDS             7684..9582
                     /locus_tag="ON488_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HCR3230324.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9576..10799
                     /locus_tag="ON488_000100"
     CDS             9576..10799
                     /locus_tag="ON488_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCR3230325.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10885..12819)
                     /locus_tag="ON488_000101"
     CDS             complement(10885..12819)
                     /locus_tag="ON488_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCR3230326.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13045..13701
                     /locus_tag="ON488_000102"
     CDS             13045..13701
                     /locus_tag="ON488_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCR3230327.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13775..14128)
                     /locus_tag="ON488_000103"
     CDS             complement(13775..14128)
                     /locus_tag="ON488_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCR3230328.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14320..15249
                     /locus_tag="ON488_000104"
     CDS             14320..15249
                     /locus_tag="ON488_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HCR3230329.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15260..16096
                     /locus_tag="ON488_000105"
     CDS             15260..16096
                     /locus_tag="ON488_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HCR3230330.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16344..17120
                     /locus_tag="ON488_000106"
     CDS             16344..17120
                     /locus_tag="ON488_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3230331.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17296..18039
                     /locus_tag="ON488_000107"
     CDS             17296..18039
                     /locus_tag="ON488_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230332.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18032..19612
                     /locus_tag="ON488_000108"
     CDS             18032..19612
                     /locus_tag="ON488_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HCR3230333.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19863..20342)
                     /locus_tag="ON488_000109"
     CDS             complement(19863..20342)
                     /locus_tag="ON488_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCR3230334.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20358..21110)
                     /locus_tag="ON488_000110"
     CDS             complement(20358..21110)
                     /locus_tag="ON488_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HCR3230335.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21227..21297
                     /locus_tag="ON488_000111"
     tRNA            21227..21297
                     /locus_tag="ON488_000111"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21259..21261,aa:Gly,seq:ccc)
     gene            21663..22388
                     /locus_tag="ON488_000112"
     CDS             21663..22388
                     /locus_tag="ON488_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HCR3230336.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22642..22908
                     /locus_tag="ON488_000113"
     CDS             22642..22908
                     /locus_tag="ON488_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HCR3230337.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22905..23336
                     /gene="ruvX"
                     /locus_tag="ON488_000114"
     CDS             22905..23336
                     /gene="ruvX"
                     /locus_tag="ON488_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HCR3230338.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23362..23664
                     /locus_tag="ON488_000115"
     CDS             23362..23664
                     /locus_tag="ON488_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HCR3230339.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            23854..24690
                     /locus_tag="ON488_000116"
     CDS             23854..24690
                     /locus_tag="ON488_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HCR3230340.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            24754..25185
                     /locus_tag="ON488_000117"
     CDS             24754..25185
                     /locus_tag="ON488_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3230341.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(25247..26569)
                     /locus_tag="ON488_000118"
     CDS             complement(25247..26569)
                     /locus_tag="ON488_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HCR3230342.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(26723..28363)
                     /locus_tag="ON488_000119"
     CDS             complement(26723..28363)
                     /locus_tag="ON488_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HCR3230343.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            complement(28804..30123)
                     /locus_tag="ON488_000120"
     CDS             complement(28804..30123)
                     /locus_tag="ON488_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HCR3230344.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
     gene            30380..30850
                     /locus_tag="ON488_000121"
     CDS             30380..30850
                     /locus_tag="ON488_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HCR3230345.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            31072..32175
                     /locus_tag="ON488_000122"
     CDS             31072..32175
                     /locus_tag="ON488_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCR3230346.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            32396..33355
                     /locus_tag="ON488_000123"
     CDS             32396..33355
                     /locus_tag="ON488_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCR3230347.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            33525..34204
                     /locus_tag="ON488_000124"
                     /pseudo
     CDS             33525..34204
                     /locus_tag="ON488_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
     gene            34294..35328
                     /locus_tag="ON488_000125"
     CDS             34294..35328
                     /locus_tag="ON488_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCR3230348.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            35342..35677
                     /locus_tag="ON488_000126"
     CDS             35342..35677
                     /locus_tag="ON488_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230349.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            35661..38141
                     /locus_tag="ON488_000127"
     CDS             35661..38141
                     /locus_tag="ON488_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230350.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            38197..39756
                     /locus_tag="ON488_000128"
     CDS             38197..39756
                     /locus_tag="ON488_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3230351.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            39753..41117
                     /locus_tag="ON488_000129"
     CDS             39753..41117
                     /locus_tag="ON488_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCR3230352.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            41288..42358
                     /locus_tag="ON488_000130"
     CDS             41288..42358
                     /locus_tag="ON488_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230353.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            42373..43041
                     /locus_tag="ON488_000131"
     CDS             42373..43041
                     /locus_tag="ON488_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230354.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            43061..43639
                     /locus_tag="ON488_000132"
     CDS             43061..43639
                     /locus_tag="ON488_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3230355.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            44040..44951
                     /locus_tag="ON488_000133"
     CDS             44040..44951
                     /locus_tag="ON488_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCR3230356.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(45329..46246)
                     /locus_tag="ON488_000134"
     CDS             complement(45329..46246)
                     /locus_tag="ON488_000134"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HCR3230357.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            46448..46885
                     /gene="zapA"
                     /locus_tag="ON488_000135"
     CDS             46448..46885
                     /gene="zapA"
                     /locus_tag="ON488_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HCR3230358.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            46943..47491
                     /locus_tag="ON488_000136"
     CDS             46943..47491
                     /locus_tag="ON488_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HCR3230359.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            47606..49966
                     /locus_tag="ON488_000137"
     CDS             47606..49966
                     /locus_tag="ON488_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCR3230360.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            50053..50367
                     /gene="trxA"
                     /locus_tag="ON488_000138"
     CDS             50053..50367
                     /gene="trxA"
                     /locus_tag="ON488_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HCR3230361.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            50549..52327
                     /gene="uvrC"
                     /locus_tag="ON488_000139"
     CDS             50549..52327
                     /gene="uvrC"
                     /locus_tag="ON488_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HCR3230362.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            52472..53371
                     /locus_tag="ON488_000140"
     CDS             52472..53371
                     /locus_tag="ON488_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230363.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            53364..54626
                     /locus_tag="ON488_000141"
     CDS             53364..54626
                     /locus_tag="ON488_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230364.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            54787..56685
                     /locus_tag="ON488_000142"
     CDS             54787..56685
                     /locus_tag="ON488_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HCR3230365.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(57015..57734)
                     /locus_tag="ON488_000143"
     CDS             complement(57015..57734)
                     /locus_tag="ON488_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HCR3230366.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLVEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            58071..58403
                     /locus_tag="ON488_000144"
     CDS             58071..58403
                     /locus_tag="ON488_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230367.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            58390..60393
                     /locus_tag="ON488_000145"
     CDS             58390..60393
                     /locus_tag="ON488_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HCR3230368.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            60412..60882
                     /locus_tag="ON488_000146"
     CDS             60412..60882
                     /locus_tag="ON488_000146"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HCR3230369.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            60903..61487
                     /locus_tag="ON488_000147"
     CDS             60903..61487
                     /locus_tag="ON488_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HCR3230370.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            61502..62488
                     /locus_tag="ON488_000148"
     CDS             61502..62488
                     /locus_tag="ON488_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HCR3230371.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            62478..62789
                     /locus_tag="ON488_000149"
     CDS             62478..62789
                     /locus_tag="ON488_000149"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HCR3230372.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            62811..64592
                     /locus_tag="ON488_000150"
     CDS             62811..64592
                     /locus_tag="ON488_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HCR3230373.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            64585..65961
                     /locus_tag="ON488_000151"
     CDS             64585..65961
                     /locus_tag="ON488_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HCR3230374.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            65968..66603
                     /locus_tag="ON488_000152"
     CDS             65968..66603
                     /locus_tag="ON488_000152"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HCR3230375.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            66633..67988
                     /locus_tag="ON488_000153"
     CDS             66633..67988
                     /locus_tag="ON488_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HCR3230376.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(68180..69574)
                     /locus_tag="ON488_000154"
     CDS             complement(68180..69574)
                     /locus_tag="ON488_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HCR3230377.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            69666..70637
                     /locus_tag="ON488_000155"
     CDS             69666..70637
                     /locus_tag="ON488_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HCR3230378.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            70634..71416
                     /locus_tag="ON488_000156"
     CDS             70634..71416
                     /locus_tag="ON488_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HCR3230379.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(71585..71956)
                     /locus_tag="ON488_000157"
     CDS             complement(71585..71956)
                     /locus_tag="ON488_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3230380.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            72090..72533
                     /locus_tag="ON488_000158"
     CDS             72090..72533
                     /locus_tag="ON488_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HCR3230381.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(72576..73385)
                     /gene="yidA"
                     /locus_tag="ON488_000159"
     CDS             complement(72576..73385)
                     /gene="yidA"
                     /locus_tag="ON488_000159"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HCR3230382.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(73404..74771)
                     /locus_tag="ON488_000160"
     CDS             complement(73404..74771)
                     /locus_tag="ON488_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCR3230383.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(74755..75585)
                     /locus_tag="ON488_000161"
     CDS             complement(74755..75585)
                     /locus_tag="ON488_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HCR3230384.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            75748..76185
                     /locus_tag="ON488_000162"
     CDS             75748..76185
                     /locus_tag="ON488_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HCR3230385.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            76261..76881
                     /locus_tag="ON488_000163"
     CDS             76261..76881
                     /locus_tag="ON488_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HCR3230386.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            77070..77576
                     /locus_tag="ON488_000164"
     CDS             77070..77576
                     /locus_tag="ON488_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HCR3230387.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            77593..78492
                     /locus_tag="ON488_000165"
     CDS             77593..78492
                     /locus_tag="ON488_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HCR3230388.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            78579..79463
                     /locus_tag="ON488_000166"
     CDS             78579..79463
                     /locus_tag="ON488_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCR3230389.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(79655..79726)
                     /locus_tag="ON488_000167"
     tRNA            complement(79655..79726)
                     /locus_tag="ON488_000167"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(79691..79693),aa:Arg,seq:ccg)
     gene            79786..81120
                     /gene="rpoN"
                     /locus_tag="ON488_000168"
     CDS             79786..81120
                     /gene="rpoN"
                     /locus_tag="ON488_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HCR3230390.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            81269..82360
                     /locus_tag="ON488_000169"
     CDS             81269..82360
                     /locus_tag="ON488_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HCR3230391.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            82401..83402
                     /gene="gap"
                     /locus_tag="ON488_000170"
     CDS             82401..83402
                     /gene="gap"
                     /locus_tag="ON488_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCR3230392.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            83512..84702
                     /locus_tag="ON488_000171"
     CDS             83512..84702
                     /locus_tag="ON488_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HCR3230393.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            84806..85561
                     /locus_tag="ON488_000172"
     CDS             84806..85561
                     /locus_tag="ON488_000172"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HCR3230394.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            85677..86975
                     /gene="eno"
                     /locus_tag="ON488_000173"
     CDS             85677..86975
                     /gene="eno"
                     /locus_tag="ON488_000173"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HCR3230395.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        28621 a        15050 c        17962 g        25448 t
ORIGIN      
        1 aaataaatag gaacaaaaaa attaaattat ttaatacaca cattagggat cattcattga
       61 aggattagaa gacaacgagg atggcgaaaa atatgattac aatagaaaag tcgttctaaa
      121 ccaatcagtt cctagtatca cacaacgcaa gccagtcgat ttggtgagat tagaggagtg
      181 aaagcaaact ttattatata agaaaaaata ttcgaaaggg atgctagttt aggtactagt
      241 gctgatagat taatatgatg cctcgtaata ttaggcgtag ttactctaga gacatcacta
      301 tggactatga tttgtctcag agtcacaaca tgttttttta tgaaaagaaa cagctaaaat
      361 aattaaattg cgcaatgttt aaactttctt aaactataac ctaataaatg tgaagaaata
      421 atgcacaatt tcttcacatt tatcttctat tctatataca taccaaccaa caaccctata
      481 tactttttca tttttactcc tcaagtaaaa ataactccta gaccgcggct acccaccgcg
      541 gtcgtttttt tattcttcaa tcaaaatcgc tttgataccc aaacctgcca agattcgggc
      601 agaagtataa gtattcaatc ctcttctgaa agtaatgtaa acttttttat cttttgggat
      661 ttcattgatt cgatctcgta actcattcat tggaatattt tttgttgccg agatactgcc
      721 agaaggtgct ttattaggtt cacgtatatc taaaaagaac gcttctttca aatcgttttc
      781 gggtatatca cttgctttga tcgtttctac gatattcgtc atttgattga ttgcgacata
      841 accagctata ttcaacgggt cacgggtagt agaatacggt ggagagtaag gcaactccaa
      901 atcaggcaaa tcaaagactg tcaagtttcc ggtgattgct acagaaagtt ctcccatccg
      961 tttatcgaca cctttttctc caaatgcttg tccacctaaa atacgaccgc tatctgcatc
     1021 aaaaatcagc tttagattta atcttgtagc ttctggatag aaataggcat ggtcaaaggg
     1081 agtgataaaa acagttttat aatttgttat gcctgatgct tttaattcat gttctgtcat
     1141 tcccgcataa cttgctgtat gatcaaagat ttttgcgaca cctgcaccaa tatatccgcg
     1201 atagcgcata ggcgtaccat ttaaaatatc tgccagcata tgtccttgac gattggccgc
     1261 actggaaagc atactttgga tcggctgacc agtcactaca ctagtcgttt cgataatatc
     1321 gccaatcgca tagatgtccg gcagattggt ttgtaactgg tcatcaacaa tgatctgacc
     1381 tgtatctgat aattgtatgc cggttgcttt caccacttca ttcttcggag aaacaccaac
     1441 agcaaaaatt agcatatcag cagaaaggac ggagccatct gataatacta tttctcgacc
     1501 tttatcacgg atctcagtaa ctcttgtttc taaatgaacg gctaatcctt ctttcagcaa
     1561 tttgtcataa actaaattag caatttctgg atcataaggg aaagcgactt gtggcaattg
     1621 atcgattaaa gtcacgtcta agccgcgatg cttgaaattc tcagctaatt ccagacccat
     1681 aacacctgca ccaagaatga cgacatgttg tggatttttt tcttcaagga acgatttgat
     1741 tcgatccgca tccgtcacac tacggaggac aaagccgttt tctgcttcaa aaactccggg
     1801 aatatccgga taatctggtc tagcaccaga agagatgatc aacttatcgt aatctgtttt
     1861 tatttcttca tttgtggata ggtctttaac tgttaatcgc ttagtagaag gatcgattgc
     1921 tgttacttcg tgtttagtaa agacatcgat gttgtttttt gttttcaata tttctggtgt
     1981 acgttcgatc agcgagtcac ggtcagtgat cacacctcct aaataataag gcaaagcaca
     2041 acttgcataa gaaatatttt ctccgcgttc atagataatg atttcgtgcg cttcattcaa
     2101 tcgacggaaa cgagtggcaa atgaaggacc gccagctaca ccgccaatga caacaacttt
     2161 cataaaaaca tctccttttc tacgttgatc gtactatgtt atggtaaaaa acagcaaata
     2221 attgtgccgg aaaattattg tttattttga atagacagaa aatatagaga aataatttgt
     2281 ggataaaacc taaaaatttt tttctatttt aaggatagat aatactttga aggggataac
     2341 cctgtatatt ttttaaaagc tgaagaaaaa tgatggatcg aatgaaatcc taatatatct
     2401 gcaatttctg tataggttaa ttcattttct agcacgagac gttttgcttt ttccattttt
     2461 agttctttaa aatagctaat aacacttttt ccattcactt ttctaaaatg tttttttaag
     2521 ctggctggac tgataaaaaa aatttgggct aattgttcaa gcaaaaaatt ttctgaaaga
     2581 tgttcttcta aatatcgtat gattggatca actaattcat ctgaataaag aatatgcttt
     2641 tttttaggaa tgactttctc atttgaaggt attgtcaata aagcaagttc ctgttgataa
     2701 tgccttggta aggaagacaa ttgaattttt tgcagacaat aagtaactaa taaggaaagc
     2761 aaatgaatgc tcatctgttg gcatagtatg aaaaaagaat tgatttcctg atcataggaa
     2821 atagctggct tactatgttt tagataatca attttgaact gttcattttt cagaaaagta
     2881 atgatagatg ttatttcttg atctatagaa aaagattgtc ccgtaatatg tgctaataat
     2941 tgctcatcaa aataaaactg gataatgata aaagtttgtg tttccttttg agtagaaaag
     3001 atttggactt cttgctgttt atcaatgaat aaaagggaag gattatctag ttctatagat
     3061 ttatgtgcaa attcagcata taaattagcg ctttcattta ttagtagtcg aaaataggga
     3121 gcagcagata aatgaagatg ggtatctatg gaataggtta gtgttttttt gacaagattg
     3181 gaggattggt tgtttgttaa caaaagaacc actttccttt ctctttttat ataaaaagct
     3241 ttctatttat aattaatgac tattataaca aaaatgaaaa gccaaaacga caagtaaaat
     3301 atttttttat ataaatattt gtgttactaa ttccgttaat atacataagt gaaagcgttt
     3361 tatataagaa cttgaaaaga aagaagggat agacatgaaa aaaagataca aattggtgat
     3421 agctttgcta aacattaccc tattattcag cttaagtgca tgtggaaaaa ctaacgaaga
     3481 agtaacagca aacatcgcag atccaatgat aaaaaaagcc actacattag aagtatatgt
     3541 cgcaaacggc aaactgacaa actatgttga aaatgctgca aaaatctata accgcaaaac
     3601 tggagcaaat attgacttaa aaattgtgaa tgtagcttcg ggaacagcaa cagtacaaat
     3661 gatcacccca aaattggtaa cacacgaaga tatgccggat attatctcca tggcagacac
     3721 ttcagcagca ggtgtgctgg aaaaatttca agatgctttt tatagtgctg atgaatatgg
     3781 attttatgac aaatatggcg atcagtttta tgatcaaaaa ttgaatattt tgcgtcaaca
     3841 aacgagtaat gaaacgatta ttccttgggc tagtgatttt accccagcac tttgttatta
     3901 tcaaccaaaa aaatttgctg aaataggtgt agattttgaa gaaatcagtt cttgggaaga
     3961 atatatccag gtggcaaaag cattaaaaga aaaaactggt agttttggaa ttgccttgcc
     4021 agaatctggg gaccaagaat tgtttatcaa catgctagcc cagcagaatc aatctttgct
     4081 tgatgaagaa ggaaatatcc gtctgaatac taaagaagcg aaacatgctg caaagttaat
     4141 caaagaaatg atcgactcag atattgtaca tttctacggt gcacaagatg ctgagaaagc
     4201 atttcaagaa tctgcaatgt ttgttgctgg cggctggtat gctacgaata tgtctttgaa
     4261 ttttcctgat gcatctgaca aatggcgcat ggctccactg attccttttt caaaagaaaa
     4321 tccaggaaaa ggtgcagtat caggaggatc aagtttttat gtccctaaag atgccaaaaa
     4381 tccacaagtg gcacaacaat ttcttacatt tatgctgaca gatgaagaat gcttagccaa
     4441 cgcactggag ctgggcgtgg ctacatctaa ctcattggcc tatcaaacag aagcagctga
     4501 gaaaaagttt gactactaag gaggacaaaa atactatgaa ctattgaata aaatcaatga
     4561 aaatacatca aatactgttt taccagccac ttattcagat gctacgtctt atttgactac
     4621 cgctgcatat aactattggc aaacaggtga ttttgaaaat tcatatctaa aagaagcaga
     4681 aaattttgct cataagtacg gcgtaaaatt aactggtgat taaaaaatat taggaggact
     4741 taacgatgat gcaatcttcg ttaccaagca agacaataaa gaacagcaag aaaaaagcaa
     4801 cagatacgtc tcataaaaaa agtgcttatg gattggtcac accttttgtt attttcttta
     4861 ttgtgacgat tttgattccc atcattatct cgtttgcttt tagttttatg aaaattggct
     4921 actcatttga atttgttgga tttgacaatt atctagctat cttccgagat ccattgttta
     4981 ttaaatctta cacgaatgtt ttgattatca tggcaggatc aattccaata acgatgctat
     5041 tagctattta ctttgctgtt ttattgaatt cagcacagtt aaaaggaaaa ggatttttta
     5101 gaactgtcta ttatattcca accattacat caacggtggc tgtagcttcc gtattcatga
     5161 cttttttcaa tccgactggg ttattcaatg gatttttgaa tgcgctagga attaacggtg
     5221 tacagtggtt aacaaatcct ttttggatac gaatatcaat gatcatcacg atgatttggc
     5281 ttagtgtagg atataacact attttatttt tagctggtct tcaagggatt tctaaagaga
     5341 tatacgaaag tgctgaaata gatggagcat cgaaatttcg gcaattcttt ttattaacga
     5401 tccccatgct aaagccaatc attttaatgg ccacagtttt agccactatc aatggcttgg
     5461 gtaatttcaa tatcccaaat atattctttg ggacttccaa tggaccagaa aattcagctt
     5521 tggtcgtagg agtcaattta tataaaacaa gttttgaaat ggttgatttt ggaaaagcct
     5581 ctgctattgc ctggacgatg gtgtttgtat ctgttatatt atcggctatt caatttaaat
     5641 tcggaggtga taaaaatgac taaacaaaag atacaaagca gaatttttac gtacgtcatt
     5701 attgtgtttg gtgccttaat atttttgatg ccatatttat atatgattgt agcttcaacg
     5761 caaagtaatc aagaaatttt aagtggcgga atcaatttca agtttgggga tatgctatta
     5821 aaaaactggc aagccatcat ggcgagatat aattatccct tgattatttg gaattcgatt
     5881 gttattgctg taatcagtac agtttcagct acagccagtt ctacaatggc gggttatgca
     5941 ttagcaaagt atcgttttat ggggaataaa ctgttgttca atacagttat gctatctagg
     6001 atggtgcctt tttttaccac attgattcct ttattttaca ttatgagtcg tttaggatta
     6061 tcgaatactt atgcaggtgt gatcatccct tcgattgcca gtacaacttc agtgtttatg
     6121 atgcgacaat atagcagtca atttcctaca gcactgatgg aggctgccag aatcgatggt
     6181 gccaatgagt gggtgatttt tacgaaaatc gctgtaccga ttttatcacc tacgattatt
     6241 actagtggtt tacttatctt tatgggaagt tggaatcaat atctatttcc attagtcatg
     6301 ctttcagata aagataaata tacggttccc ttaattatca aaaatatgac ggtttctagt
     6361 acaggtgagc caattaatta tggcgcaatt atgctaattt tagcaacttc agtgatccca
     6421 atggtcttga tttatgtgtg ggcgcagtct aaatttaagg agaatgacat tggagctgca
     6481 aataagtaaa aaaaataacg aatgttaacc atctagttcg ttctaggagc aactccacat
     6541 tcataaaaat taaaagaatg gcgggatatc catgaatgaa cagacgaagg aatggtcaag
     6601 aaaaattttg aatgtagctt ctgaaaagat agatgcggaa ttagacagaa tggggaataa
     6661 aattccatat atttcttaca acggaaaata tacagacgta ataaaggaca gaggaatcga
     6721 ctggtggacc aatggttttt ggagtggtat tttatggcag ctctttcaca agacaaaacg
     6781 agaaaagttc aaagaggcag caatacaaca agaacaatta ttagaatctg ccctgtacca
     6841 tttttcagac gttcatcatg atgtaggttt tttattctta ccatcggcta ttgcacatta
     6901 tcaacagtct caaaacaaac atagtcgaca actagggtta catgcagcta cggtacttgc
     6961 tggacgctat aatatttcag ggaactattt agtagcatgg aatgaccata aacctggttg
     7021 gatgattatt gatagtatga tgaatttacc attactgtat tgggcttcga gggaaactgg
     7081 tgatccgagg ttctctaaaa ttgctcggca gcatgcagat acaacagcta agtatctagt
     7141 gaggaaagat ggatcaaccg ggcatatcgc agaatttgat gcagaatcag ggaaatatat
     7201 tcggttactt ggcgggcaag gatacaatga gaattcttgt tggagcagag gaaatgcatg
     7261 ggctttatat ggattcgcgt taagttatcg ttacacaaaa aatccgtact atctagctat
     7321 agcagaaaag atagcagtaa attttattca gaaaatcgaa aaaactggtt atattcctct
     7381 cattgatttt gctgtaaaag attcgaatat tgataccagt gctggagtat gcgctgcatg
     7441 cggtcttctg gaattagcag gatatgtttc ctctgtacga tcaaaaatgt atcatgaagc
     7501 tgctatcaat atactccaaa agacagaaaa gcactatgca aattggaata tggatgaaga
     7561 tgggatcatt ggaggcggag cagaagcata ccatagagaa ctgacttata atgtgccact
     7621 gatctattct gattattttt ttattgaagg cttacttcga ttagaacagt cggaattagc
     7681 tatttggtag taaaaagagg agaaaataca atgaaacatc cagtaccact attaaggacc
     7741 agacaggatt actttgactt atttaaaaag ataaatcaac cactccagcc gttttatcga
     7801 gcaagtggcg cacaaattga ttatatacat caaggggtag gatatggaaa taaaattgca
     7861 ggaatggaag gattctctcg ggttttatgg ggagcggggc ccgcaattga ccaattagat
     7921 gaacgatggt tgaaattaat tctatcagga ataaaagctg gaacagatcc ttcccatccc
     7981 gattattggg gagaaataca tgaaagagac cagcgtatgg tagaaatgcc cgcaatgtta
     8041 ttagcgttat atcatcatga acaattatta tggaaaaaat tagatacagg agaaaaaagc
     8101 cagattattc attggttctc gcaaattttt gaatatgaat gtgcagatgg taattggcaa
     8161 ttttttaaga taattgtcgg aacaattatc caaaaatttg gttatccagt taaagaatca
     8221 gcactgaaag aagcatttga taatatagaa aattgttatc ttcaaaatgg ctggtatcga
     8281 gacagttcaa gaggtcgcca agattattat aatccttttg catttcatta ttatggtttg
     8341 atttatagcg tactagaacc agaaaagccc attagccaga tatataagaa ccgagctatt
     8401 gatttttcta gagactatat tcattttttt gcggaagatg gtgcaaatgt gccttttggt
     8461 cgaagcatga tttatcgttt tgcagtttca agcttttggt cagctatgtt gtgggccgat
     8521 cttttgcctt ttaaattagg tgaaatcaag gggttagtca atcggaatat aagatggtgg
     8581 atgcaaaaag aaatatttga tgaaaaaggt atcctgaata ttggttatac ctaccctcaa
     8641 ttgacattga ctgaacccta taatagtacg ttatctccat tatggctgaa taagattttt
     8701 ttattgttgg cgctacctga agaccatgag tattggacgg ctaaagaaat gcctatgcct
     8761 attcgtgaag gaactaaact tctttcagaa gccaatttgc tcatacaaca tgataatgga
     8821 catacatttt ttttgaatgc gggacaatta gggccaaatt tccatacatt gaccaatgaa
     8881 aaatatttaa aatttgctta ttctagtcaa tttggttttt cgataccgcg agcgaatcaa
     8941 ttgaaagcag aaatggcaat ggattcaatg ctagggattc agcgagcgga cacatatatc
     9001 acgaccagtt ttaagaatga gagcatcaaa acctatggac agttcatcgt tcgaaataat
     9061 gtacgagaca ttgtatgtaa gaaagaggta cttgcctcta catgggaacc tactttacag
     9121 gcaaaaatca gaacttggct tattcctttt gaaggctggc agattcgcgt acacaaagta
     9181 gaattagata cagaatatgt tctatatgag acagggtttg ctattgaatg ttctcctgag
     9241 aaagaaggaa taatcataga agaagacaag gaaaactata gggtgagtga agctggcttt
     9301 tcaggtatta tctgtttaag tgacgatact attaaacgaa aatccacagc tattatgggt
     9361 ttgcccaata caaacttgat gacatgggaa aacactttta ttcctggatt agagggtaca
     9421 tttggaaaag gaacccattg gctcggaaca ggagtggttg ctcatcaaga tcgggattat
     9481 agtttagaag tatggaacaa tcgtcccaaa attgattttg atgggacaac cgggctaact
     9541 atccaaaata aaaacaataa aaaaagacta aaattatgct aaaggctggt ggggaaatgc
     9601 ttgataaagt gatgtttgaa gagataatac atccagaaaa atggataaat gaatgttata
     9661 aagaattaat ggaaaaagaa tggaataatg agatcgagcg ttgtcgcaga cacacggaga
     9721 ggttaatcaa acgtatcagt aacagtcagt atcaattccc aagcgagtgt cctataaaag
     9781 gacgttatcc attaagagac aatattggtt ggacagaagg attttggaca ggaattaatt
     9841 ggttgttatt tgagaagacg ggtgatcctt tatttcaaca aacagctgaa aaagcagata
     9901 tagattttat ccacaggatt gactgtcaaa ttatcactaa tcatcacgat cttggttttt
     9961 tgtattcttt atcaaccgta gcagattata aaataacggg aaatcgaaaa atgaaggaag
    10021 cttcaattga tgctgcagaa acattacttc agcgtttttg ggagaaggca ggagttatac
    10081 aagcttgggg agatcctagt gatccttcac aacaaggtag aatgatcatg gattgttgca
    10141 tgaatcttcc attattgtat tgggcgagtg aagaaactgg aaatcaaaaa tataaaaaag
    10201 ctgctcaggc tcatattcaa aatgcagcag attatttagt aagagaagat ggttcaactt
    10261 atcatacatt ttatatggat gtcaaagatg gaaaaccaag atatggaagt acgcatcaag
    10321 gttatagtga taattcctgt tgggctagag gccaagcatg ggggatttac ggttttgcat
    10381 taagttatcg ttatttgaaa gaacaaaaat attttgattt aagcaaaata ttagccaatt
    10441 attttatgaa tcggttgcca gaagatacca tttgttattg ggatttgatc tttgatgatt
    10501 ctagcagaga agaaaaagat acatctagta tggtgatcat ggtttgtgga ttattagaat
    10561 taatagaatc aggtctatta gacaaaacag aaaagaactt ataccagtct gctgtttgga
    10621 aaattatgcg acaattgaaa gaaagatatg ctacaacgga agaagaagat ggctttttaa
    10681 cacagtctgt ttataataag cccaaaaata atggggtaaa tacaccttgt atttggggtg
    10741 attactatta tttagaagct ttagtgagaa tgactagtaa ttggtcttct tattggtgaa
    10801 aaaggtaaat atggaatttt tgtttgataa aataaaaaaa gaaaaaccaa aacagcatga
    10861 atggtttctg ttttggtttt ttcgttaatt ttcatattct tctaattcca agcttagttc
    10921 ttcccattcc gtcaattttg tttcttgatc ttgtctagca gcttctaaat cttggttcag
    10981 ctcattgagt tttacgtgat cttccaggtt ttctggcgcg accatttctt gttccaactg
    11041 atcgatccat tcatcgatcc gcgccatttc ttcttcaacc tgagtaattt ttcgttgaag
    11101 gctacggata agcttttgct gttctttgct ttggtaataa tcagatttgt tcgtgggagc
    11161 aggagcagat tctggctcat cttgtgccaa caattcggcg atttcttctt cttcctgctt
    11221 tttctctaaa taataatcat agtctcctag atagactttg ctgccatttt cagagagttc
    11281 gacgactttt gtcgcgatcc gattgatgaa atatcggtca tgggaaacaa aaagcagtgt
    11341 gccgtcataa tcgatcaatg cattttctaa tacttctttg ttgtcaatat ctaaatggtt
    11401 tgttggttca tccaaaatca aaaaattttc tttgttcatc gctaacttgg ctaaagcaac
    11461 ccgtgctttt tcaccgccac ttagcagagg gattggtttt tctacatctt cgccagaaaa
    11521 taagaaagca cctaaagcac ttcggatctc tttttctgga gtggtaggat gctcatccca
    11581 caattctgct aggatcgtct tgtttgtatg cagatcagct tgaccttgat cgtaatagcc
    11641 gatggtgaca tttgtcccta gcgtttcttt tccacggata aaagggatct ggtgaatgat
    11701 tgatttcagc aacgtcgatt tcccgatacc attcggacct actagagcaa tcgcttcttg
    11761 acgacggata tctagattga ttggttcaga taaggtgaca ttatcatatc cgatagcggc
    11821 atcttcgatt tgcaagacta catttccaga aggcttttct atactgaata gaaagtttgc
    11881 ttgtttttca tccccttgag gacgatccag ccggtccatt ttttctaatg tctttctgcg
    11941 gctttgcgct cgttttgtgg tagaggcgcg aacaaggttc cgagcaacga agtcttctaa
    12001 tttatggatt tctgtttgct gcttttcata agccttccat tcacttgcta actgttctgc
    12061 tttcaaatct agatatttcg aatagttacc tttgtaatgg cgcatttttc ttctgcttaa
    12121 ttcatagact tcattgacta ctttatctaa aaaataacgg tcatgggaaa caatcaataa
    12181 tgcaccagta tagctttgca gataattctc aagccaggaa agtgtctcga tatctaaatg
    12241 gttcgttggt tcgtctagaa tcaaaatgtc agggtgttgc aaaagcatgc gagctaaagc
    12301 taaacgtgtg cgctgtccgc ctgataaagt atcgattttc tgatcataaa atgaagaatc
    12361 gaatttaaac ccatgcaata cggaacgaat ttcattttca taaccatagc cgtttcgatc
    12421 tgaaaaatcg tgttgcagcc ggtcgtattc ttttaaataa gaactataag caggtgtgtc
    12481 tggcgtacct tcgctaatga aaatctctag ctcgcgcatc cgctcttcca tttgtctaac
    12541 ttgttcaaaa gctttcagca tctcgttcca aactgtttca ttggaatcaa gtcctgtgtc
    12601 ctgagcgagg tatccgagag tcgctgtttt atttttagcg atctttcctt catcaggtgc
    12661 ttcaattcca gcaatgatct ttaataaagt cgattttcca gcgccatttc tgccaactaa
    12721 agcgacacga gcgcctgtac tgatttctaa atgtatgttt tcaaataaga cttctgcacc
    12781 aaaatggcga gcaatctgat tggcttgtaa taatatcatg gaatcctctt ttctactttg
    12841 tgaattctcc tcaaataaaa aactattttt caattagtag tctaccataa attccattat
    12901 actgcgagat ttgcagaaat gataaataaa tgaataaaga ataaaatttc acaatatctg
    12961 agcaatggaa ttgatttttt cctataaata ctgctatgat ggagaaatca aagatgtaat
    13021 tagacaatac gtggaggtca tttcgtgaaa gatcatatta ttccaaaggc gacagctaaa
    13081 agactgcctt tgtattatcg ctatttaagg attttaaata atgctggaaa gaaaaaagtg
    13141 tcttcaactg aattaagtga agccgttcaa gtagatagtg caacgatccg tcgagatttt
    13201 tcttattttg gcgaattagg aaaacgtggg tatggttatg atgtagaaga tcttatgcac
    13261 ttttttgcaa agacattaaa cgacgatcaa ttgacaaatg ttgcgctgat cggtgtaggg
    13321 aacttgggaa gtgctttact aaaatacaaa ttccatcaaa gtaatagcat acgtatcagt
    13381 tgtgcttttg atgtgaatga ggaaatcgtt gggcgcatcg tagacggtat ccccgtttat
    13441 ccaatggaag atatgtcaga acaaatcaag atccaacaaa tcgaagtagc aattttaacg
    13501 atacccgctg aaagagcaca agaagtagtc aatcagttaa cggaagcagg aatcaaagga
    13561 atcttgaact ttaccgctgc tcgattgaat gctccgtcag atgtattgat ccaaaatgtt
    13621 gatttgacga atgaattgca aaccttgatc tatttcttgc attctgacgc aaatgcgcat
    13681 tccgaaaata cagcagaata aaaataaaaa gcgattgaac aaatgaaggc aaaactttca
    13741 cttgttcaat cgcttttttc tgtttggaca acgattattt tgttcggaag atttcttcat
    13801 aagaaaggga atcatcttct gctgtcagtt catctagtag ataacggatt tttttaaagt
    13861 cgatgaaccg tgcttgccga aagacttctt ttccttgatg aaaaatcagg acaactggcg
    13921 cagtcagcac ttcaaattta ctagctactt ctggtgtttc aaatgcatcc aaatgaagtg
    13981 ccggaatatc ataatgtgtg agaagttcct ctagtcgtgg acgaacagcg tgacaaacac
    14041 tgcaattagg catcgaaaga taaatgacgg caacggatga ctgttgcagt atgtcttgaa
    14101 cttcagtcaa gttagtggtt tgtttcattt ttattctccc ttttatgata gaagtgatat
    14161 gtatgagacc ttaatttaat gggaataaca gaaaaagtca attgaagtgc tttggtaaaa
    14221 aataagagtt gtgtaaaaat ttacagagca acttgttttt tttgaataaa agcgtatatt
    14281 tgcaaagcga atgaactaga aataaaaagg aggaaactca tgttttcttt tattccaaat
    14341 tcggttttgc agatgagtac gattttctta tcgatcgtta ttgaagcatt acctttcgta
    14401 ttattaggct gtcttatctc aggcgcctta caagtatttt tgaccccaga acgtgtgaag
    14461 agatggcttc ctgaaaatcg tatcttctct atttttactg gttcgatctt aggatttttc
    14521 tttccttcat gtgaatgcgg catcgtaccg atcgttcatc aatttgttaa aaaaggcgta
    14581 ccagttcaca cagcgtttgc ttttatgctg actgctccga tcatcaatcc aatcgtgatt
    14641 ttttccactt ttatcgcatt tggcaattct tggcagatgg caagctggcg ggtgataggc
    14701 agcttttttg ttgcccttgt gattggtgtc tggcttgcct attttcaaaa agacgctgta
    14761 ttgaaagaaa aaatcacgtc taaagtagca gaaaatcacc atcatcatgt ccatgaagaa
    14821 gaacaaagtg agaagaatga accaaaaaat cagctgatcc atcaaactgg gcatgtgttg
    14881 acacattcaa tcgacgaatt ttttgataca ggtcgttatt tgatcattgg cggattaatc
    14941 gcagctgcga tgcagactta tttaccaact agaattatgc taacgctcgg ctcaacaaag
    15001 attttagcca ttatcatcat gctgttattg gcctttacga tgtctctttg ctcagaagca
    15061 gatgcgttta taggatcttc tttgttaagt ctgttcggca cagcacctgt agctgccttt
    15121 ttggtctttg gcccaatggt cgatatcaaa aatctactga tgatgaaacg atattttaca
    15181 ggacgcttta ttttatcgct gatcggactg attgccctta gcgttattgg attcacatta
    15241 tttatttagg agggaaaata tgctgcggtt tttgatttta tctgggtatt tcgaattgat
    15301 gatgtacttg caagtttctg gcaaactcga tcaatatatc aatgtccatt atcgctactt
    15361 agctattctt tcaatgattt tatctgctct tttggcttta gttcagctgt atttgtgggt
    15421 caaaaacgga aaagcagaag aaaaggcaca cgagcacgat catgaccatg ggttgtcaaa
    15481 accttatcaa cgtggaatcg cttatgtact gctagctttg ccagtaatcg tggggacgtt
    15541 gtttccaaca gttagtctcg acactacgat cgtagaagcc aaaggattta atttcccagt
    15601 aagtaaagaa tcagtagggg atccggagat gcagacacaa tacttaaagc cggataccag
    15661 tatttatttc aacaaatcag actacttaga ccaaatgaat gagttgaaag aaaagtatgg
    15721 ggataagcaa actatcaaga tcacagatga aaactattta gaagttatgg agctaattta
    15781 taattaccct agcgaattca ttggcaaaaa aatcagctat gaaggatttg tttaccaaac
    15841 accgaacgat agcaatacag atatcttctt gttccgattc ggcattatcc attgtgtggc
    15901 agattcagga gtctttggtt tgttgacgca tatgccggaa ggagtaacgg ttaaaaatga
    15961 tgaatggtat aaaatagaag gaaccatcca atcagactat tatcaaccat tcaagcgtga
    16021 aatcccatct gtagttgtta caaacgctga gaaagtctct gctccgaaaa atcagtatgt
    16081 gtatcgttct ttttaaaaga acaaaataaa taaacatagc tcagacagct gacacgcaag
    16141 gacgtcggtt gtctggcttt ttttgcatga tgtattcatt tgtttgatat ttattttaga
    16201 agcagcatcc tgaaagtatt tgatatcggt ttcaaaggtg ttggaaaaga ttgtgaagag
    16261 aattacaatt tattcctaac atgtatgttg aaaagttgta tgaaatgatt ttgatagtaa
    16321 aatatcgagt ggaggtactt tttatggtaa cgcgtatatt tattttggat gatagtttgg
    16381 tttttgaaaa aatgctagta gaaattttgg aagaatccag aattttatta agtccttgga
    16441 aatttgagat cgttcaggga ttgaacgtta tacaatttgt tgaattcatt aaaaataatg
    16501 aaatctattc ctcagatatt tttttcctag acatcgattt gaacgcctat tatagcggta
    16561 tcgaactagg cgaaatgctt agagaaaaga atgaaaagtg taaaattgtt tatctaacgt
    16621 ctcatccgaa taaagcaata actgttatta atcgaaagat tacgcctagt ggttatttga
    16681 taaaagaatt cacttatgaa aaaaataaaa aaagcatcca aagttactta ttgaaagaaa
    16741 aagaaaacta tcctgttcaa catgctacga aaaaaaggtg gacaactgtc cgttatggta
    16801 atagcgatca ctatatccat tacgatgaaa tcctttatct aatgagcatg ccaggttata
    16861 aaaataaaat aggcctagta ttgaaagatg aagagattct cgtaaacggc acaattaaaa
    16921 aatataaaaa atcactcgaa tatgagtatt tatgtaaaga tttaaaagct tatatcatta
    16981 atactgaaaa cattacatct attagcagag taaacgaaat agtaacattt gcaaatggag
    17041 aacaactaga gatgggaaag agaagtattg ataaactaaa gaattttatg caagaaaaga
    17101 tagaaaatga atcattttaa agaaaacaaa gactcatatc ttacctgtta gaagagtgtt
    17161 ttcctgtaga agagaacaac ccaagtagca gcctagtcgt ttctatcctt ttttgttatg
    17221 cactcttttt gacatttact ccaccaataa cgaagggtac aataaaaagt aataacaaac
    17281 aaaaggagta cagaaatgat tgaattcatc aatgtaagta aaagttacgg gaaaaaacaa
    17341 gcattaaaag acttgtctct ctcgataaga caaggggaaa tttttggatt tttaggacat
    17401 aatggtgccg gaaaatcaac tacgattaaa agtttagtta gtattattga accatcatcg
    17461 ggaacgattt tagtagatgg aatgaaattg acggaaaatc gattgagtat caaacaaaaa
    17521 atcggttatg tgcctgattc cccagatatt tttttacaat tgacggctgg agaatattgg
    17581 gacttgattt cagctgccta tgaattagac acacaaaaaa aagaaaagcg tttagcagaa
    17641 ttgacagcgc tttttgatat gtatagtcat caaaatgaaa caatcgcaag tttttcacat
    17701 ggaatgcgtc aaaaaacgat tttgatcggc acgttgctgc cagatccaga tatttgggta
    17761 ttggatgaac ctttgcaagg acttgatcct caagcagcat ttgatttgaa agaaatgatg
    17821 aaggctcatg ccgcaaaagg aaaaacagtc attttttcta cacatgtatt ggataccgca
    17881 caacagttat gcgataaact ggctattttg aagaaaggtg aattgattta tcagggggca
    17941 gttagtgaat tattgaatgg ctcacctgat gaaacgctag aaaagattta tttgaaaatg
    18001 gctggaaggc aagcgacagg agatggaccg tatgtataag cgacaattat tagaattaat
    18061 tcgagttaat cttttatatg ttaatccaca gctcacgaat aaagcaagag agaaaggaaa
    18121 aaagggaaag cgattaacta tctatctttt gtctcaaaat cttttttcag ggctgatttt
    18181 tttactgatt tacggatttg ctatgtttgc tatgaacttt gttaaattgc caggtttctt
    18241 tacttattac gtggcacttt ttggtatgtt aggtttaact caaagtatat cagtcattta
    18301 taatatcttt tttgaaggaa atgacctgca agtatttttg cctctgcctt ttggacaaga
    18361 acaggttttt tcagcaaaga ttttggtagt tgctttgacc atcattcctt ttgtttttcc
    18421 gcttctagtc atgtttattt taaccggatg gcgagctgat ctagggattt tgcttactat
    18481 cattatctca atccttttgt tttctctatt tttgattatt cttttttgtc tggctagttt
    18541 gattgttttt ggtttggctc gaacagcagt gtttaaaaaa catagaaaaa cagtttctag
    18601 tatcttgctt ggcagctcga tgctgatcgc atttgctgga atcatgtgga tgaatcatca
    18661 aacggggact attgaaaatg agttaacaga tcggcatccg atttcgatat tattgccatt
    18721 ctatgatgct gccagtcagc cactttctca acaaggttta ttgggttggg gaatactagc
    18781 tatcacggct ctgggatttt tccttgctgt aaaacagctg atagtaccaa agcttacaga
    18841 gcaactgact gattcaaaca gtgagttcaa aataaaaaga acccataaaa agaaccaaaa
    18901 tgtgcatcag cttttattta gttacaatgc tcaattagta aaagaaccta atttgattat
    18961 gcaagttctt tcttcttcct tgttaactcc aatcattttt attcttgctt ttgccctagg
    19021 aggcgaaata aaattaactg atttagataa taagttaatc ggtgttgttt tcctggtagg
    19081 gatcgcattg gctttcttaa cagttaatca gacttctttt atcagcaatc ttatttcttt
    19141 ggatcaagaa aattttctgt ttatccgttc tttgccaatc tctatgaacc aatatttaaa
    19201 agaaaagttc agattcggat ggatattgca gagtttttta actggtggga tcgcattatt
    19261 aagcggactg tcttttcagc tgcctttgtt ttttatccct agcttgctat ttggttcttt
    19321 attcggctgc tacttattgt cactacgtta tttcgctaga gattatcggt tgctgctgct
    19381 gaactggacc aatattaacc aattatttaa cagaggttca ggaagtttgg gtttagtcgc
    19441 aactatgatg ggttcattga tcatcagtat tattcttatc gtcttatacg gaatgttggc
    19501 tttgttttat ccattttggt tagtgaatat tcctgtgatc ggtttagttc taatactttc
    19561 cgctctatgg atcgtttatt atcaacgaac gttttggaaa aaatttgaat aaagaagagg
    19621 ggccgtgaca aaaatcatgt cgcagcccct tttttacaga tagagggtgt tcaaaagtca
    19681 gtttctcagt attaagtcaa ttttatgtaa aaatgtgaga agctattttt acaaaacttt
    19741 ttttaatact cataattact tcttattgct cctgcggtta cttgtcgcaa tgtttgtgag
    19801 atattttgtc atcgctcaag gctgaacgtc tctttcacaa ccttttcttt gttacacttc
    19861 gtttatttaa aaagccgttt ttttcgtttc atcatgattg cgtcacgctt tactttgaaa
    19921 ttacggatgt tatggttaaa gacttctgat aatacaagac ctaaagcgat tgctccagca
    19981 atcataattg cttggaccgc ataatgagcc gcttctcgat aggattcagt aacgagattt
    20041 cgaaccgctt gataagctaa accaccaggg actagaggaa ccatcccggg aatattgaaa
    20101 atcgttacgg gcattttcaa acgtttagag aaaagatcgc tgatgaatgc tactcctaaa
    20161 gaaccaagca atgaaccaaa agcagcagat ccgcctattt gaacacagat ccagtagatc
    20221 atccagccaa aagcaccaga aagaccacaa caaatcaatg aacgcctagg tacatttgta
    20281 ataacggcaa atgccgcagt cgctaaaaaa ctaaaagaaa actgaataaa tatcgtcccc
    20341 atacttgtgt tcctttccta ataaaaaagc tggaaaataa aagcaatcgc aaaaccgatc
    20401 atcgtagcag tcatcatcgc ttctgttccg cgagaaactc ctgagacata atgtccagct
    20461 agcaaatcac ggatagcgtt cgtaatttga actccaggaa ctaaaggcat cacacatccg
    20521 ataatgatta gatcctgatt gcttcctaag ccaaaacgta cgctgtagat agcggctatg
    20581 ccaatcaata aagaagataa aaattccgat aaaaatttga ttctaaaaaa tttcaaacta
    20641 tatagataag ctgcgtatcc caatcctcca atgactaaag tcacaggtaa atcggtcatc
    20701 tttccgccaa ataacaccat aattgttcca ctgatcactg ccgcgctaac gatttgcaac
    20761 cagacaggaa agaaagaacg gtctcggtcg attgcttgca gttcgcagta aagttcttct
    20821 aatgttagct ctgaagcaac atatttacgt gaaagatcat ttacttttac tactttttct
    20881 aaattaatcg aacggttggt aatttgttcc attcggatgg tcgaggtacg atcaagacca
    20941 ataaagagac cggtttgagt gacatagctg accaaacgga aatttccaga agctaaagca
    21001 attcgactca tcgtatcttc tacccgatac atctccgcat tgctttccat catgattttc
    21061 ccagcgagta aacaagtgtc cagcaacaga tctaattctt ttcccgtcat agcatcttct
    21121 ccaataattg attgattagt tttattttac tacaaaacat atcggaagcg taaagaataa
    21181 aaaaacttga ggaaggagtg aaagaggcgt atactgtttt tgtatcgcgg gtgtagttta
    21241 gtggtaaaat cccagcttcc caagctgatg tcgcgggttc gattcccgtc acccgcttaa
    21301 aagaggctgt gaaaaagctg ccctgcatca agtaataaga atagtcaagc aaaaaagctt
    21361 cttatgtttt tgacttggtt ggacttatta ccgcagatgc aagcttttga acactgttta
    21421 ccaagaggtc gtacagaagc cgtttagttt tgagtattaa gaaaaatttt ttgaatgata
    21481 ataaatacct tgtaaatagt gttttgtgat tgagtagaga cgatgaatcc gtctcttttt
    21541 ttgtattctt aagccgtcta aaaactggtt ttattttttt actgtttcta tttctttcca
    21601 gtatttattt ataggggaac atatgttaag atttagggaa ctgttagtaa aggagtaaag
    21661 aaatgagcaa aaaaacaacc aaggcgatcg tggggatcgt cgctgctgtg attgcagggg
    21721 cactcggtat ttccaccaca caaaaagatt cagatatctt ccaacaaatt acaaccattt
    21781 ttgattccac accgcaagct tctcaagtag cggatgtgcc agaatatgat ggaaaacatc
    21841 aagaaataga aatcaatggg aatcagccgg agtttacaaa agaggatctt agtctttcca
    21901 aagggacatg ggaaagctat tcaaatatag acaaattgaa cagagtagga caagccaatg
    21961 cgatgttggg aaaagacttg tttcctactg aaaagagaga acctttgtat attgatccga
    22021 caggttggaa acaaaagaaa ttaagtgacg gacaatggtt atacaaccgc agccatttga
    22081 ttggtttcca gttgactggt caaaataata acattaaaaa cttaatgaca gggacacgtt
    22141 cgttgaatgc tccgtacatg cttgcccacg aaaatgatat tgcggcatat atcaaggaaa
    22201 caaatcatca tgtacgctat cgtgtcactc ctcatttcga gggaaatgaa ctggtagcaa
    22261 gaggtgtgca gttggaagca gaaagcattg aagacaaaaa aattgaattc aatgtcttta
    22321 tctacaatgt tcaagatggc tacaccatca attatgagac agggcaagca acgaaaacga
    22381 aaaattagta gcagcaattc gaatttttta tgaactttat gaaaaaattg tgtaaaaaca
    22441 tactttcaaa gaaatatagc gtatacttta tggaaagagg gcttttgaaa aagccacaga
    22501 aaaaaggaaa aatcagacaa atcgtgtttc ttaatttatt cagaagtttg gaatatttgt
    22561 ttgtagtttt ccctttcttc gagtaaaata agggtgtaga aggtaagctg gaattacctt
    22621 gcgggaaaga ggtgtagaat catgggtttt acagatgaaa ccgtacgttt tggttttgac
    22681 gatagtcgca aaaaagaagt gagcgaaaca ttagcgattg tttatcgggc tttggaagaa
    22741 aaaggctaca atccaatcaa tcagattgtc ggctacttgc tttctggaga cccggcctac
    22801 attcctcgtt atcgtgatgc acgaaatttg attcgccgtc acgaacgcga tgaaatcatg
    22861 gaagtaattg tcaaagacta cctctcaaat catggagtga atttatgaga gtaatgggct
    22921 tggatgtcgg ttctaagaca gtaggcgttg ctgtgagcga tccctttggc tggacagctc
    22981 aaggagtaga aatcattcga atcaatgagg cagaagaaga gtttggtttt gatcggttga
    23041 aggaattagt ggcgcagtac gaagtagacc gttttgtagt tggattacct aagaatatga
    23101 acaattccat cggaccaagg gcagaagctt ccatgtcata tggagagaag atcaaagaac
    23161 tattctcctt gccggttgat tatcaagatg aacgactaac cactgttcag gcagaacgta
    23221 tgctagtaga gcaggcaaat acttcaagag cgaaacgaaa aaaagtcatc gataaattag
    23281 cagctgtgat gattttacaa aattatttag acggctcagg taagcaatta ttttaataat
    23341 aaaaagaaaa gaggtaatct tatgacagaa cataaccatt cccacgaaca cgaaggacac
    23401 gaacacatca cattggtgga tgaccaagga aatgaaacat tatacgaaat cttgctaaca
    23461 gttgacggac aagaagaatt tggacgtaac tatgttcttt tatatccagc tggtgtttca
    23521 gaagatgaag atgtagaatt acaagcttat gcatacatcg aaaacgaaga tggaacagaa
    23581 ggcgagttag aacaaatcga aacagacgca gaatgggata tgatcgaaga agtattcaat
    23641 acattcatgg cggaagaaga atagaacaaa agaatcgata aggtgtaaga aaagctggac
    23701 tctctgaaaa gtagagcccg gttttttcgt ttagcactaa atttccttaa aaagtagaaa
    23761 agctttcgaa gcctcgtttg tttcttttac tgtataataa aagaaaagag taacaatcgc
    23821 taaaagatat aaacaagaga aaggaaatac aagatgattg gtctgattta ttttgtggtg
    23881 atcgttctgg cgaacacagt tggcgctatt tccgggatgg gtggaggcgt gttgatcaaa
    23941 ccgattcttg atcttatcgg cgcccattct gttgcaggga tttcttttta ctcaacagtt
    24001 gcggtattca cgatgtccat tgtttcgact gtgcgacaag tatcaagcgg gaaatcactg
    24061 aattggcaga ttgtcggttg ggtatctagt ggagctgttg ttggaggagt agtcggcaac
    24121 attgtattcg aagttttttt acagttattt gaaaacgaga agcatgtgca gctgatccaa
    24181 atttttttga cggtattgac cttggttttt gcgttcttct acaccaagca tcatcagcca
    24241 aaatttcatt tgacgtcatg gacttggtac cttatatgtg ggggggttct gggcttttta
    24301 gctagttttt taggtattgg tggtggacca gtcaatgttt ctttgttgat gctgatgttt
    24361 gcattgccaa taaaagaagc aacactatat tctctatcta cgattttctt ttctcaactg
    24421 gcaaaattgg taacgattgc tttaacaagt agctttatgc gctttgattt atctatgttg
    24481 ttttatgtta tccccgctgc tgttattgga ggtttgtggg gagcaagatt tagcagggtt
    24541 ttgtctccaa aaaaagtgac ctttattttt caagcgattg tcatcgtggt tcttttgatc
    24601 aatctttaca atgctttcgt catcttgcaa acattagaag gatctggatt caagcaagtc
    24661 aaaatcactg aaaagtcttt ttttaagtga aaaaaggagt atactgtgat aaaaaaattc
    24721 atttaaaaaa ataaaaattg gctggtgatt tggatgttgc gggaaatgcg tttaggagat
    24781 gcagaagcac tacgagaaat caatgcggaa caattaggat atgatgtacc attaaccgtt
    24841 acggtgagac aaatgaagaa actgttgaag gagccagaaa aaaatttttt cttggtctat
    24901 gaagatccta cttctaaaaa agcagctggc tatgtacaag cggagtccta tgaatcgatt
    24961 ttcagcgatc cgatgttcaa tattatggca cttgctgtgt ctaaacatgc tgaaaaaaga
    25021 ggaatcggaa aggccttgat gactggcgta gaagaagcga aaagacgagg aatatcagca
    25081 ataagactta attctgcaga atacagagta gaagcacacc gattttatga acgcatcggt
    25141 tatcattccg ataaaatgca aaaaagattt ttgaaaatcc tgtaaatttt tatcaaaaaa
    25201 tacctggtca tcaagccgat acttgatgat caggtatttt ttttgactaa gaaagtaatt
    25261 gcatcaagaa acctgagatg atcaaaacga tggcaccacc aagccgattg cccatttgag
    25321 caaaagcaat aagttccatc cgattagctg cagataagac agctacattt cctgtaccac
    25381 ccatcgagtt gttgcataag ccagcagtaa tagttgattc gattggatat aaaccaaaca
    25441 aacgaccgac aaatcctgaa actactgaaa tcgcgataac acttgtcaaa cataagacaa
    25501 caaattgcca tgtcaaagca gaagccaata catttagatt caataacgca ataccgatac
    25561 cggcaagaac agctgctgtc aagtttttga caatcaagtt gttgaacatg atagctgcat
    25621 cttcgtaata ttctggtaat aggtttgcga ttttacagat aacaacgata atgatcatga
    25681 atgcgtaagc atggacttta ggaacaaaat agttacagat ttgtcctaag atgaagaaag
    25741 tcaatgatac catcaaaccg acacctaatt gtggaatgga aggttttaca tttctaggtt
    25801 ttccatcgcc aaggtcgcct ttttccatta atttaccatt accgttgaat tttggcattg
    25861 attgtcccgc acgagcaact aacgctgcac caatgatagc taggacattt gtcattgctg
    25921 tcgcaggaat caggcgggaa atgatagaag aagcgtccgt acctaaaaca tttgcataaa
    25981 tcgttgataa aggtacagct ccggctccaa caccaccagc cattgcgggc aatgagatat
    26041 ataaaacgga atttgcaaaa ccatttccga taagcatacc tacgagtcct acggcaaaaa
    26101 aggagacgac cattgaaata agtgcaacgg gaataaaacg aacagaagct ttcatcaata
    26161 gattacggtt cataccaagg atgctaccag taatcaaggc agcaatataa aagtctaaaa
    26221 agcccatatt gctgacaaag ttttctgtgg attttactac atactcaggt aagatcccaa
    26281 atgtagcaat cgcggcagag gcaaagatcg caaaaacgga gccaccacct aaataacttt
    26341 tgactatagg gatttttgtt ccgataaaat gaaataaatt accgaaaatg accaaaacag
    26401 cgattgggcc aatcatattc gtcggtaatt ttcctaaagc cattgcaatg atcaggacaa
    26461 ggaccatgat caaataaagg ggcaaactta cgccggtaat ttttgttgac caaaaccctt
    26521 cttttttctt ttcctcaact gcagttgcgg ttgttgtttt ttgtgccatt tttacagatc
    26581 ctttcttatt ctgtatcgta tgaaaaaagc caaagagaag cggcaaaaga gcagtagttg
    26641 gctggctgct gttttgccgc agtcgctttt ttctttttag acgtcataca aagtttctgt
    26701 atgttctttt actataacaa tcttaatctt ctaaagattt atattcagga acccatttag
    26761 cagattcaac agcttctttg atatccgtga tttcttcacg attcaatttt tgtgcaacaa
    26821 ctgattttgc gacagtttca gcaatcgttt gagagaattc agtgattttt gctactggag
    26881 gcaagatagc tgctcctggt tttgttacat caacgattcc gcctaatgct cgactagctt
    26941 gagaaatgat ttcagcattt actcgtgtag ctgttgaagc aatcaaacca agccctaaac
    27001 ctgggtacat caacgcatta tttgcttgac cgatttggta agttacaccg ttatattcca
    27061 catcagcagc agggatacct gttccaacta aagcttttcc gtccgtccat tcaatcaaat
    27121 cttttgcttt tgcttctgcc aattttgttg gattagacaa aggcatgatg attggacgtg
    27181 gggtatgagc cgccatttct ttcacgattt cttcagtgaa tgctccaggt tgggtagaag
    27241 taccgatcat gatcgttgga tggattgctt ttacaactgc ttctaagttt gtcaattcat
    27301 cagcattagt gaattctgag cgtttacgag cgaatgggat ttgaccagga gtcaatcctt
    27361 ttgtatcttc aaacaataaa ccctgtttat ctacttgata gaaatgttgg cgtgcttctt
    27421 cttcaggtac accttgacgg atcatttcat ctaaaaggat gtttgcgata cctacaccag
    27481 cagtaccagc accaaatgtc aagatcgttt gatctttcaa ttgctcacct gatatattca
    27541 atccacctaa tacaccagct agtacaacga ttcctgtgcc ttggatatca tcattgaaag
    27601 tagtgatttt atcttcgtat ttttctaaga tcgttgcagc atttcctcgt ccaaaatctt
    27661 cccaatgtaa taacaattct gggaataatt cagtagctga ttgaacgaat tgatcaatga
    27721 attcgtagta agtttcgcct tctacacgag catgacgatt ccctaagtat aatggattat
    27781 tcaataattc ttcgttatta gtaccagcgt cgattgatac aggcaagact tgtgcaggat
    27841 tgataccagc cgcggcagtg tagaccatca atttaccgat agcgatgtca acaccgttca
    27901 caccccagtc acccatacct aagattcctt ctgcatctgt cacaacgatc aaacgaatgt
    27961 cgcgtccatc tgctgcgttt ttcaaacttg ctttgatatt ttctggttcg tcgattgaaa
    28021 gaaatacagc atcttgtggt ttcaagaaaa tttcgttgta ttgttcgatt gaatccgcaa
    28081 cgacaggatc ataaacgaca ggcatgaatt caactaaatg ttcgcccatc aatttataaa
    28141 acaatgtccg gttcgtattg aatagattca ttaagaagat acgtttttcc aaatcggtct
    28201 gtttgcttaa gtattgaccg taagcttgga cagattgttg ttccaatgtt tggacagtac
    28261 ttggaagcat accagtgatt ccgtattttg cccgttcttc ttttgtaaaa gctgttcctt
    28321 tatttagaaa aggattattt aataagttta gccctgtaag catgaatgat tcctcctaag
    28381 ttttaataca aacgaagtat aggagtcaga tgaggatata gtcaaaaaga gcaggtataa
    28441 taaattttat ttatatgagt aatagagtca aaagaaatca aaatagcggt atttgttctt
    28501 tttatatcaa caatccttgc ttgattacta tgcgtatctc ttatatgcta aagaaagaaa
    28561 agtagaagaa taaaggatat gttagataga taaatagaat cctgaataat tcatagcttt
    28621 aattctttgg cacattttat tgaaatatgt atcactaata tccctatcaa ctgattttga
    28681 ctaaaaagtt acttcaaaca ttcactgttc aaaaatattg aggaataaat tttgggtgta
    28741 aggcattttg agcatacttc tccctggata acttcccagt aaaaaaatcg ttagattgtt
    28801 ggattagatc cattgactgg ctcgcctcag gcgagcaaag accctgtaga attcattctg
    28861 atacacatga taactagata atttgagata gactcgtcta cccgtttgga ctaatttccc
    28921 agcaactttc agaaacttca atcgaataga atgaatggtc attccctttt ggacttcttc
    28981 aaagccaatc gttcttaaga agttgactaa gttgtaagct atcaagctga gcatcattcg
    29041 gacatgattc tccaaaaagc gaggactgtc tgttttgtca aagtaaaagc cagctttcgc
    29101 ttctttaatg aagttctcca ttgtgccacg tttggcatag atagaaaaga tggtatcagg
    29161 agaaacattt tctgatagat tcgtcacgat aaattcatgt cgaaagagta gttcgcccgc
    29221 ttcacgtgtt gagcgtatac acacgcgacg actttgtgac caggattgtg cttgataagt
    29281 ggtcgagaag tactgaactt ctcgttcttc ccacttttga ttatcgccat aaagtactga
    29341 tttctcagct atttgaccta gtctacgatt attcttcagt cgaataacat aatgactctt
    29401 ttttgattca cacgaatcat acacaccagg tgtagcgaac ccgctgtctc cacgaaccaa
    29461 gatgtcagtg tttggtagag agtgattata gtgctctaat aaaggtgtga gaaactcctt
    29521 tacgcctttt gatgtatatt gatttcctga acgtagttca gcttttaaga agtcaccagt
    29581 caatccgtca aaagctacca atggatggta accataggtt tggtagtgtg tattataatt
    29641 cgtttgttct tggtgaccaa atgtatctga atgggtcgaa tctaaatcaa tgattaattc
    29701 cgtatcatta cggatgaggc gtgctttatc gataagttct tggttcaaag cttgaagttc
    29761 atggatattc tcctcagata gtcgatctaa aaatcgggaa agtgaagatt gagaagcgag
    29821 ttctttccta tctaaaacag ctttaaacac aggatcttgt ctcaggagat tagctgcaga
    29881 atcagctgag taaccagcaa ttaattgcat aatgaactgc tcaagtatgg ataagttgtc
    29941 atgagtaaaa tacgctcgtt cgtcttcaat gtgaatgtgt tgcttagcca gttcagaaaa
    30001 accaaagatg ttcatcagct ctttcactag gacgagaccc gaatcactcg ataattgacc
    30061 acctgtatga gaaatagtga tatttgaatt gaattttact tggtttttgt gtaagctagt
    30121 catgaaaaga actcctttct tttggttggt ttagtcactt taaccatagc agaaaggggt
    30181 tcttttttca tcacttaacg ggtgaagatg aaaaagtaat tgtaagctgc cgtgaggcag
    30241 tttcacatgg ttttaattaa aagtatgaat tattcaggta gaatctctga agaataaatc
    30301 acgtgatcgt gacgataaaa tacacttacg tcaggtgata aaaaatacat aagtagaaaa
    30361 ctaagaggag gaacagaaaa tgaaagaagt tcaattgatc agaaaaagcg aactatcaga
    30421 aggtggttgc aatgcatgcg gcgtagtaga agcaacaagc tatacattaa agcttggtgc
    30481 caacaaagcg ataatctctg agttgacagt aggcggtctt gtggacagtc tggcgcttgc
    30541 tgaaggtttt attggagaag atatttatga gatgttttca gaaatccgtc agttaaaaaa
    30601 aggggaaaac tgcatagagg ttcatcatga gagcccgaat gtgagattca aacgtggtga
    30661 taatgagatg atcttcaata atcatgtgtc cgatcacacc gagctatatg gaatcgtgaa
    30721 tcaaatacta actgagcttt ttggattggg accttatgcg ttcaaggaag aaaacggtaa
    30781 tccaaaatta aacgaagaat ggcaagaaac gattgaaata caaagaaaca acccgcactt
    30841 atttcaatag gcatccacag tatttcgtaa aagggacttt gacacgactt ttgtcaaaat
    30901 cccatcgttt tttatctatt tgtgttctaa acatttcttt cagagtagta acaactggaa
    30961 tgactgaaat gtaaacagat tatttgcctg tatcaatacg gaagagtaat ataaagtgtg
    31021 taaacgctat catattattc attcaatttt ttatagaggg aaggcattga aatggaaaaa
    31081 acgtatcaag caggtacaaa tgaaggaata gtggatttta tcaatatgga agatttagaa
    31141 atagccgctt cacaagtgat tccagctggt ggttatggtt acatcagcag tggtgctggc
    31201 gacttattta cttatcaaga aaatgaacgg gcattcaatc atcagctgat tattcctcat
    31261 gtattaagag atgtagaatt acccgataca actacacatt ttgacaaaga aacgctgact
    31321 gcaccaatca tcatggcacc agttgctgct catggcttag ctcatgtgaa ggcggagaaa
    31381 gcttctgcaa aaggtgtagc agattttggg acgatctata cagcaagttc ttacgcttct
    31441 tgtacattag aagagataag agaagcaggc ggggagaaag caccgcaatg gtttcaattt
    31501 tatatgagca aagatgatgg gatcaatttg gatattcttg aagtggccaa gcgtaatgga
    31561 gcaaaagcaa tcgtattgac agcggatgca acagttggcg gaaaccgtga aacagaccgc
    31621 agaaatgggt ttaccttccc actgccaatg ccgatcgttc aggcttatca atcaggagta
    31681 ggccaaacga tggatgctgt gtacaaatct tccaaacaga agcttagtcc aaaagatgta
    31741 gaatttattg ctgctcattc tgatttgcca gtctatgtga aaggtgtcca gtcagaagaa
    31801 gatgtctatc gttcattaga atctggtgct ggcggaatct gggtatctaa tcatggtggc
    31861 cgtcaactag atggtggtcc agcagcgttt gattcgttgc aatatgtggc agaagcagta
    31921 gataaacgtg taccaatcgt gtttgacagc ggtgtacgac gcggacagca tgttttcaaa
    31981 gcaatcgcat caggtgcaga tcttgttgct attggcagac ccgttattta tggattgtct
    32041 ttaggaggaa gtacaggagt ccatcaagtg tttgatttct ttaaaacaga attggaaatg
    32101 gtcatgcaat tagctggaac acaaacagta gaagatatca aaaaaataaa attgcgtgag
    32161 aatcgtttta tttaagaaac aaatgacgaa aaaaatagga gtgcggcaga tgatgccgta
    32221 ctcctatttt tatagttcaa ggatgtcact aatagaataa tttgaaacga aaaaataaaa
    32281 ttgaaatatt ttttcatact tcgccgattg taaaattaag ctagacaact aaaaaaagtc
    32341 atttgtgcta cactcaaaat agttccgacg aaagaattat aaggagtgag tacaaatgac
    32401 ctataaccat cttacaccaa ctgaactcgt aatgatagaa gcttatttca atcaatcaca
    32461 acctgtttca aaagtagcca atctgttaca acgttctcga caaactattt ataaggtcta
    32521 tcgttttctt aaatctggtg gaagcgcaat gagctactat aaacaatata agaaaaacaa
    32581 acgtaactgc ggaagacatc cgattgtttt acctgatgag caacaggaat acattcaaaa
    32641 aaaggttgtt caagggtggg ctcctgatgt ccttattggt cgagcagagt ttcctattgc
    32701 ttgttcggta cgcacactgt atcgaatgtt taaagataaa acctttgaca ctcacgattt
    32761 accaatgaag ggaaaaagaa aaccaaacgg tcataaagaa aaaagaggaa aacaagggtt
    32821 tcgccggtca atccgagaca gaaagacaga ctatacccag tttgatcatg aatttggtca
    32881 cctggaaggt gacactatcg tgggtggaaa acataaaagc gcggtcatca cattagttga
    32941 acggctatct aaagtcatca ttaccttgaa acccgaaggc agacaggcta aagacattga
    33001 aaataggctg aatcaatggt ttcgttgtgt cccaaaaaac ttatttaaat ccatcacatt
    33061 tgattgtgga aaagaattct caaattggaa aaagattagt aataccaacg atatttcaat
    33121 ttattttgcg gatccaggaa caccttctca acgaggattg aatgaacatt caaatggctt
    33181 attacgtaaa gatggtttgt ataaagctat ggattttaat ggtgtatctg aaacctttat
    33241 ccaatcggtg gcatcgaaac gaaatcatat tcctagaaaa tcattacact atcggacacc
    33301 aatggaagta tttttgagtt acgtcacaaa agatgatttg tctaacttaa tttgacaaac
    33361 gaaacttaat aaaaaaggaa gaatattcat gtaaacgatt ttattgtttt tttctctttt
    33421 atacaaaaag ggtcataatt tcaagtaagc ggatgaattc atgaggattt tttgcatact
    33481 gtctctacta tacttaggtc actaagaaaa aggagtgatt tattatgaaa aagaacatga
    33541 ttgggacatt attactttca acacttcttc taggcggctt ggcaacacca gcttttgctg
    33601 agggtcaagc gacttcaaaa ggagatatta cctttactga accaacaaat accgtggagc
    33661 ctcttaaccc tactgatctt caaaaccagt agagccagca gatccggaaa atccagcaac
    33721 tggccagaca ggtcctttaa cactggatgt agttcccgaa ttgccatttg gtacacacga
    33781 gattgaaagc ggaacaaaaa cgtatcaagt agacgcttca aaaaacgata caccttatct
    33841 ccaagtatca gatcgtcgag gtgtaggtgc agatggccaa gcacaagggt ggaacgtgac
    33901 agtttcggtt tcagattttg taaacggttc acaagttttg caaggcgctg aattagattt
    33961 tggaacatcc actgttaaaa gtacgtcaga taacgaatcc actggaccaa ctagtcaaac
    34021 tgtaactggg ttgagtaaag caagtgcagc gacaccaata tttacagcag caaaagatca
    34081 aggtctggga acatggcttt ctgtttatga tccagcaaat atcacactga aagtgccgaa
    34141 agcagcagct ggaacattca cggctgattt gacttggaac ctcgtggctg gcccagtagc
    34201 atagagtatg aaataaattc aacaaactgc ggtgaaaata ctataggtga aggatttttt
    34261 accgcagttg ttgttgaaag gatgtggtgg acaatgaatc aaagtaaacg actgtttgtt
    34321 tcgttttttt ctattttaag tctatttttc atttttccgt caatcagcca agcaaaggat
    34381 tcagcaggag actttggaat caaaccggta tttccagaga accaaataga taaagcaatc
    34441 ggttattttg atttattagt ggcaccggaa caaaatcaga cactagaagt aattatcagc
    34501 aattcttcag atgaagaacg aacatttgag gtctctgtca atccggcggt aacgagtgat
    34561 ggtggaacga tcgattatag tcaaaaaaac ccaacgttag atgagacatt gccgtttgat
    34621 gtccgtgacg ttttgctcat tgcgaaaaag gaaatcaatg tatcagcaca tgcagaaaca
    34681 actgtaccta tagaagtgaa aatcccagca aaaagcttta agggacgtgt attagcgggt
    34741 attcatgttt cacctaaaga agaagctgaa acagaaaatg ctacagaagg agcacaaatc
    34801 aaaaatcgta ttgcttataa tctcgcagtc gttttacaag aaagtcaaga gacgatagaa
    34861 ccggatctga aacttttatc aggagatttg gacgaggtca acgcaaagcc aactgttcag
    34921 cttcgtttcc aaaatcctca gcctaggatt atcagcaatt tgatatttac gagcaagatc
    34981 ttttatgaaa atcagcttta tattgaaaat acgtctaatg catttttagt tgcaccaaat
    35041 tcgaattttc acttgaatct tgatttagct ggtgataaag caaaagccgg cgattaccgc
    35101 gcagaaatca tagcaaaatc aggcgacagt aatgaatggc gatttacaca aaactttacg
    35161 atcaaaaaag aaaaagcaca aaaagtaaat gaaaattccg tttttgcagt acaagaacaa
    35221 tctttcccat ggctttatgc aggattggtt gctgcagttc tagtgttatg gttgattttg
    35281 ctgtttttgt gggtccacaa gaaaaagaaa aaaggagaaa caacatgatg aggtgatttc
    35341 gttgaaaaca tcgatcttat tgggagggat tattgcaagt ttgctgttct tcagctggca
    35401 agagccagtc caagcagata ccaaaagttc aggtacgatt acattttatg atctaagtcc
    35461 aattccgcat ccaagtggtt cagtcaatgg cgcatcaaaa cagcagacac agctaccgat
    35521 ttataaagaa tctaatcaac atggcgtatt cccggagacg aatgaacaaa agatccgttt
    35581 tctttatttg atcattggta tagaattatg gcttcttgcg tggttgttgt tatggagaag
    35641 aaaggaaaag gaggatgaac atgttgctac aaaataaatt ttcatttttt cgctccttct
    35701 tttttacttc gctttttgtt ttaagtatat ttatcttttc accttcggca gaagctgttg
    35761 gagcaacgcc tcctgccatt tcttatgatc catacacgta tgaaaatatc gtacctccaa
    35821 atggtggacg tagtgcagtc aatggcggga agcttgtcca actaactggg gctaaccaat
    35881 tgcctaaatt gactgctact tatttgaacg atggttcaaa tgatccttgg aaaggtggca
    35941 cggtccgttt tcattgggaa agccatgtga aactaacaaa tgtacttgat ttggtgaata
    36001 tcactgcaca aggatttgca tttgtggcga tcatcaattt gccggaacat gtatcaagca
    36061 gtgatgtatt aaaagcaatt gactggaaca acgcctactt gtatattgcc ggtgccccca
    36121 tcaaggttac tagcggaagt ttattatcag caggaagcca taccttgcgt tttgggatgg
    36181 ggtcgtggga tacaaatact ctattgacag atattattgc tattattacg cgaggcgaat
    36241 tcaacgtgga cgatatcccg cttcaatttg atgttacagc taatgtcgcg aagatgacag
    36301 aaaacggaga taaatatgat acgagtccaa acaaaatttt gaccaagggt aaattacaac
    36361 cttctatgtc taaaaaggcc gttttttctg ttgattttta tgattcgaat aatattatcc
    36421 aagatcgtat gttcaattcg attttagctc cagctgcagg tagattttat cctaaattaa
    36481 ctggcggaaa cttgaatcca ggagcatatg cattttctgc aagtgcagag ataaatacgt
    36541 ggaatagtta catctcacca agtgattcaa caggaaaata taatacattt gctgatacca
    36601 cagaatacgt ggatggaaat aaccagaacc ttccaggctc taccaatagt cggacattga
    36661 cgatggggct gactgaagga cggtttgatc agttgccatt tagtcgcttt gatcgcgtag
    36721 tcaactattt tacaggaaaa aacgttacac aaggagcaat actgactcat actccagcaa
    36781 gcacaagtgg attgaatcag acagccaata tcgtgtacag tgggaaagat gcgcaaggcg
    36841 gattgctttc tcctgttgct ttaaaggtat tggagcagta caagctagac ggaacggttt
    36901 taccaacaaa cttaacagcc gatagtcagt ggggaaagct cctttcttct gcatcgtacc
    36961 aagtcacggc caattggtca gcaactgaac taaaaaaggg ttcgatccat tacaggcttt
    37021 attcgaaagg aacccaaaaa ttagcgacag gatggacaga tcaacttttc caaacgatcc
    37081 aatcaaataa cgggggtgta aatacagcta cttctacact acctgcattg gcttcagggc
    37141 aatattattt tgattatcgc ttggtggacg atgtacttac taacatgtat ccgtcttttg
    37201 cgtacaaatg gcagtctgaa caagctggaa tcaccactct tcctcaaata acagtggcta
    37261 attttccatc tgtgagtgca gatagtcagc taaaaaacct tagcagacaa cctgagacag
    37321 gagatcccct gtctgctcta tcaggagata cgattcaaga aaatgtgaca ttcacgttaa
    37381 caaaatctgg ggatgcgata accgacaaaa aaatcacgat ctcacttcct gaaaatacta
    37441 cttatatcaa tggttcctta aaattaaatg gtacaactat cgcagatacc ggcattcaac
    37501 aaggagtttc tgtcccagca gatctattga gcaaaatagg agataccatt catcttactt
    37561 acaactatca attaaatact gtagatactt ctttacaatc cgtcagcata ctgacaaagg
    37621 cagctgtact ttccagcaat attacattag cagatggtgc taagcttcct aacccagttg
    37681 tccaaacatc tgctaaaaca attcttgtcc ccaaacaaga attaacatta gttaatgtac
    37741 cagatgattt tacatttggt aacgatctcc ccaaaccgtt gaagacaagt tattatgaat
    37801 caaaaggcga tttttctttt gatgtgcggg atactcggct tccaagcacg tctccttggc
    37861 aactgacagg tacattgact tctttattta agaatgatca aggtcaagaa ttaagcggaa
    37921 caaaattata cttcaatcat tctggatcaa agcaattgat tcagcaaggt caaaacacgt
    37981 tgatttatga gagtgatgga acagctaaag gagaggttct cgttgacttt cccgataccg
    38041 atggtttact cttagaggta aatagcagta cgaatgctca acctggcgca acgtatcaag
    38101 gcatggtcac atgggaactg acagctgggc caaccagcta agtgattaga atttgtatgg
    38161 atctgtgata actgtcacag atcctctttt tcaaggatga gaaggaaact tctgctgtta
    38221 aaatcagaaa tgcttgaagg agtggacttg gaacttttca gtttgcttga aaaaaatgaa
    38281 caacggcaaa tcaaactttt ccaactttta ttagaggaaa aaggagaggt ttccgttaat
    38341 aacgtactta cccgcttatc agttgatcgg gctaccttga aagaagatct gttttattta
    38401 caagctaact tggaaaatat caaacaattg gaaattgtta tccaagaagg gaatatttta
    38461 ttaatcagac atggaaatat agcagcagtc gatgtttatt atcattgtta cttgcgctat
    38521 tctacaaaat atcagatact tctttatctg ttggaaaatg gctcatttga tcggcagaaa
    38581 cttgtcatgg aacttaatat cagttcggct actttgtctc gcagagtgaa ggaattaaat
    38641 gattctttaa atgagtttca tctgaaaata aaaagcgggc ggctgaccgg tccagaaagt
    38701 caaattcgtt atttttattt ccaattattt tggtttggac gtccctatct tgaaaacaaa
    38761 aaagaataca gtgatttatc aggaaacact tttttagatc tgctgcaaaa agagtttagt
    38821 tttgctatta cagaagaagg acgattgaaa tttgaaatat ggctttccat tatgaagaag
    38881 cgaatgcgct gtacgaaaaa atccaaacca gattatagca atcttcctgt tggattgttt
    38941 caaacgacac aatttttatt ggacctccat acatttttga cccgttactt ctttcaatat
    39001 gcctttcctt ggaatcaaaa tgaaacgttg gttttttatc ttttcatgat cagtaacttt
    39061 acattagata cacataactc gcatgtccag gagtttttga taagcgaaaa atacaaagac
    39121 gacgtagtag ctcaattgaa tcgaacgttt aaacaatcga tagaagaata tttctctttt
    39181 tatgtttttc cagaagagat ttcgcaaaag attgcgttga cagtgatgca aaatcacgct
    39241 cattttgcct attttagagg atggatgaat atttttggcc aagaaggatt aaaacagcgg
    39301 ttaactgaag tagaagataa acaattcctg gttttatgtg aaagattggt cagacaaaca
    39361 tttgctattg ttgattttac tgaagtagac gaggaaaatg cccgctttga attatttgct
    39421 cgctatgcat ctattttacg gacgctgatc aagcagttag aattacgtct gcaaattgct
    39481 tatgatcttc cttatgaaag gctaatggcg gatatcgtga aagaaatcat ccaggaacaa
    39541 ttgctgaata cgatcaaata tgatttagtc gaatacgaga aagaaaagca gtatgatatc
    39601 attttgacta gccaattgaa agagtacccg tcacagaagt ccgctaaagt ttttgtattc
    39661 actagcaacg aatataatta tgatttcccc tatttgaacc aatttttaaa agaatgttat
    39721 ttagaaaaat tgaatttaag gatgaataaa acatgaaaat cgtgatcatt ggtgcttccc
    39781 atgaaggcat cacagctgcc ctaaatctaa gaaaacttca accgaaagca gaagttttac
    39841 tgatcgatga agatcataaa gatggactag gctatgtttc aaatggaatc aacctttatt
    39901 taaaaggaaa gatacgtagt ttagctgaag ttgcccataa catgcggact cttcaagaaa
    39961 gtggggcaaa actgatcacc gaatggagag taactgaact tgatccagac aaacatcagc
    40021 tcatcctcgc atccaaagaa ggaaaaaacg agaccataac ctatgataaa ttaatcgtag
    40081 cgacaggttc ctctcctgtc accttgtata aacaaattga agctgaaaat gtctacacct
    40141 ataaaaatct agtgcaatct aagcaagtac ttgccgcttt aaaagaagca aaagaagtag
    40201 tgatcttcgg tgctggttac attggattgg aattagcaga tgctttgaga aataaaggat
    40261 acattattca tctagttgat tatatgccga atgttttatc aagatatttc gataaggata
    40321 tgatcaacag ttttcaaaat cagctgcaaa ctaagcaaat aaatttttat ccaaatgaat
    40381 tcttgatcga ttggaaaaaa tcagaagaga aagtagtatc cgtacaactt ctgtctcaaa
    40441 caataaaggc agatatggtc attttttctg cccaaactcg tcctaatacg acattgttaa
    40501 aagaaaaagt ggctttgtat gaggatgaga ctgtgatagt caatgaatat ctgcagacaa
    40561 gtgatccgga catctatgcg attggagata tcgtcccagt cagttttgac aaaaataaac
    40621 ggcatctctt tttaccttta gttactcgag ctgtacatat ggcaagagca gtagcgctaa
    40681 ctttgagtgg tcagccaacc gcttacgacc tcagacaaaa gataacagca gcagtcatta
    40741 tagactactt tttaggaact gtagggctga cagaagatga agcgccattc ttggaacaaa
    40801 ataccggttc gtgttcagga gaatttgatc tatttccaca atacgacgaa gaaaacaaaa
    40861 cagtaaatgc aaagctgatc taccatccgg atacattaga aataattggc ggacagctga
    40921 taagccaaga attcttatta tcagatttga acctgcttgc ggatatcgtg aaacacaaaa
    40981 ctacgattcc acagctagca gttgaggatt ttggatttct gtctgaatac acctctcgtt
    41041 ttcactacct caatgagtta gcttttaaag tactagctaa gagagcaaat agcaatagag
    41101 tagataaaag actgtgagaa atatcacggt cttttattgt gtggggatat aataaatatt
    41161 aatcaatcga gaataaaaaa ttcatataat gaaatagcgg aagaattttt tgagcataat
    41221 attcgccaaa aatttatcaa gtgataaaat tgttgtataa aatgattatt tcaggaggag
    41281 gagttaaatg tttttagcat taaatgaaat tatgcattca aagttacgtt atgcgttagt
    41341 tgcaggggtg atgtttttga tcgcctacct ggtatttttt ttgactgggt tagcttatgg
    41401 cttagctcaa gataatcgaa cagcagtcga caagtgggag gcagattcga ttgtgctttc
    41461 gaaagatgca aattcaaatc tagggatgtc catgattact aagaagatag cagaagaagt
    41521 cgaaggtggg aaagtggcgt atcttgccca aacacctgga gtcgtgacta gtaaagacag
    41581 tacagaagaa ggaaaaatca atgttagctt cttcggtatc gataaaaatc aattcatcat
    41641 gcccaatctt gttgaaggaa aagcttttga taacgatgat gaggcagtag gcgatattag
    41701 tttgaaagaa gaatatggtc tagccatagg agatacagtt aagttatctg gtagtgacaa
    41761 gacgtttaaa ctaactggct ttacggatca tgccaaattc aatgtctcac cagttctcta
    41821 tacaaccatc aatgcttacc aagaaatccg cttcgaaaaa gaagatacaa gtgaaaatgc
    41881 acggattaac gcaatagttg tcagaggtaa aatcagtaat ttacctgaag atttagaaca
    41941 gatcaaaatt tctaaattca tcaatgaatt acctggatat aatgcgcaag tattgacttt
    42001 tggatttatg atcggatttt tgatcgttat tgcggctatt gtgatcggga ttttcattta
    42061 tgtactgacg atgcaaaaga ttaatatctt tggtgtaatg aaagcacaag ggatcacagg
    42121 aggatttatt gcgcgttctg tagtggcaca aacattcatt ttatcatttg ttggtattct
    42181 tcttggtcta ttaggaacag tgggaacatc ccttgttcta cctgatgcgg ttccattcca
    42241 aagcaattgg ctgttttttg gcgtcattag cttgttgatg ttagtagtag ctgtgttagg
    42301 cgcactattt tctgttcgga caatcgtaaa aatcgatccg ttgaaggcaa ttggataaga
    42361 aggaggaaga acatgaaagc aatagaattt aaagaagtag aaaaaagttt ccaagatggc
    42421 gaccaagtag ttaaagcatt gaaagaaaca accatgagta tcgataaagg ggaatttgtt
    42481 gcaatcatcg gtccttctgg ttcaggtaaa agtacttttt tgactttggc aggcggattg
    42541 cagacgccta gcagtggctc tgtatttatc aatgatcaag aattcagtaa tcaaaaagaa
    42601 agcgaacgcg ttaaactacg ttttaaagaa attggcttta ttttgcaagc ttccaatctg
    42661 gttccttttc tgacagtaaa aaagcagtta ttattagtag ataagattaa acatgaacat
    42721 cgtcaaaaag aagcaaacga attatttgag cagcttggcg tggataagtt gatcaacaag
    42781 tatccagaag aactatctgg tggagaacgg caaagggtcg caatcgctcg tgcattgtac
    42841 aatgatccgt ccattattct agcagatgaa ccaactgcta gtttggattc agaaaaggca
    42901 cgagaagtag tcgatatctt ggcaaaagaa tcaaaagaca aaaataaagc aacgatcatg
    42961 gttactcacg atacacggct gattgacaaa tgcgatagaa tatttatgat ggaagatggt
    43021 gtattgaaag aaaaagaata accaaaaagc aggtggaaaa atggtccatc gatacaacaa
    43081 agatacacag caaaaaattt tgaaagaagc gactgacttg tttatgtcca agggatatct
    43141 cggcacttca acaagagaaa tcgcacaaaa agttgggatc acccagccca atctctatca
    43201 ttatttcggt gataaagaaa aactatatac ggcagtttta gaaaaccact taaaagatgt
    43261 tggaaaagct ttgagagaaa tcgttcaaac aagcgaaacg ggatttcaag taaccttgac
    43321 aaaaatggcg cagtttttga ttgagacaca tctggtcgat ttgtttctga tgcttcacga
    43381 tcttgaaagc aatctttcaa aggaaacaag agatcatctt ttctttctat ggaagaaaaa
    43441 ttatcgtgaa ccttttgaag aaatcttttc agcaaaccaa tctgtgctaa gaaatgggat
    43501 ttcaaaagaa atcgcagcaa ggcatttttt cttagtgtta gcaccttaca tcactcggtc
    43561 gaaaagacct gtggaagaac cgctaaatgt ggcgcaattg atcgatttat atttgaatgg
    43621 tgtattagga gaagcgtaaa gctgttatat agggagaaaa tagttaggtg aagaagcaag
    43681 atatgacgaa gatcgttata tcttgcttct ttatataggt agtttttcat aaatacaaat
    43741 ttgttattct ctcatgatta tcagggtata tttttattta ttatgtcggt gttccaggaa
    43801 gtgttttaat ttaataacga agaaattaat tgtttgtaga atgaaggaaa ctatttattg
    43861 ggtagatgaa tcaccacgaa tagtcaaaag gagatttcag gatatgccaa aaatgaaaaa
    43921 aatcatttta gcagtaatgt tattttctac ggttatatct tttacagccc cttttttgct
    43981 tacttaagct gattttaagt tttggccctt agtctggatc tacgaggtga gagtcaagaa
    44041 tgaaaaaaat aattggagct tttgtatttg caatcattat cattattatc tgttttcaaa
    44101 tagatgtttt tggtcaaaaa aagatagttg gacaaacggt cagcagtacg aacagtacgg
    44161 ttacaaagac aaaggaatca tttgatgata cagaacaaga gacattaatc aaaatcggaa
    44221 aaaatgaccg tacactatat acagatgact cgctaactac cccacttgca actataaacg
    44281 gcggagagct ggcggagttt ctttctgaaa caaaaaatgc ttatcagatc aagacaaatg
    44341 atggctatac tggatattta gccctcgaag atggaaccaa agtcacaaag aatatacaaa
    44401 caaaaccgga agagctatct gatgcagtga ttgtattaga tcctgggcat ggcggaaatg
    44461 atactggggc attaagcaat gatgaacaaa cagaagaaaa agatataaca ttaagtacag
    44521 ccataaaagt aaaaaaggcg ctagaggatg ctggagcaac ggtttatttg acccatacta
    44581 cagatgaatt agtacagctt ggagatatat gcgactacag tgaagaaaaa aaggcagatg
    44641 tctttatcag tttacacgca gactctacgg aatatgcgaa tgaagcaact ggaatcacga
    44701 catattatta ctatggacaa gaggaaacat tagcacagac aattgctgac tccttcactg
    44761 atctgcctct ggattcaaga ggaatctcca ctgggaacta tcaagttctt cgagaaaatc
    44821 ttcaaccttc tattttaatc gagatgggtt atatgaataa tgatagtgat ttaaaggaat
    44881 tagtaacaga cagttatcag cagcagattg ctgcaagttt gacacaagca ttgaccactt
    44941 attttcagta ataaataagc ccagccaaac aaaaatagct cctcatattt ttcgtttggc
    45001 cgggcttatt atcgcagatg caagctttta aacaccgttt aaggaagagg tcgtgagcct
    45061 gccgttcaac tctgagtcac aaggagcaat ttcaaaaaac agcttctcat gtttgatgac
    45121 tattgtgact tgtgaccgag gagttggcat gagaacaccg tttaagaaaa aggttgtgaa
    45181 atcaacgttt tgttctgagt attagagaaa caaacggaaa aatagttcct catattttgc
    45241 cgtttgttga gctaataccg aggatcagat gattgaacac cgtttattcg gaacaaggga
    45301 ctgtgacatg acttttgtca cagttccatt atttttttag tagcttcaaa gctttttctg
    45361 tattggcaaa atgaagtttg gcatattttt caagcatagg catgccgcct ttctccaata
    45421 gttttgccgc tacttggtca gatttcgttc cagctcctga cggaagggtg attccagctt
    45481 cagctgatgc tttgtctaac tcttccaaaa agctggcacg actgatgata gaagcagcag
    45541 caacagctaa atgatattgt tctcctttag taacgaagta cagtttttct tgtaattgat
    45601 ttttttctaa acgcgcatat tttttaaaat ttgcttccgg cgtaaactga tcgatcaaaa
    45661 tcgcttctgg tttttctggc tcgatttttt ttagcagcaa atggatcgct tgattgtgca
    45721 aagcgacttt catccgaacg gcattgtatt ttggttggat ctcattgtat ttttctggag
    45781 ataagacaag cagtttatag gggatggttt tttttaagat gtcagcaagc tggatgattt
    45841 ggctatcttt taactctttt gaatctctaa caccaagttt acgtaattct gcaagctgat
    45901 cacgtttcac ataagcagca catactgtta gcggaccgaa atagctgcca tttccgacct
    45961 catcactacc taaaacggat aattgactga tattttttgg caaagaagag gctgtttttg
    46021 ctggcttggc ttgtttatcc tgtgcctccc cccatttatc agcttctatt gctgcattcg
    46081 taccttgaaa catcactttt ccggatgtat aagcggtaat ggtcgtcccg tctttttttg
    46141 cagcaaagct agtataagga atctgtttat ttaacaaata agagcgatag tatgctttca
    46201 tttgactaag ttggtcgttt gttgctttga taatgacgtt gctcataaaa ttctcctcgt
    46261 ttttatacat aaaactatac cgcaactcac gacttttcgt tttctaagag attgcgagac
    46321 atagcatttt tttaaagttt atcatataat agttaagtat gtgaaaaata tttgtggaga
    46381 acggtgaaag aaccaacttc atggtacact aaataaaact ttcatcaaat aggaggaaat
    46441 gattcgtatg gcgcacgaaa aaacacgcta caaagcggtg attgccaacc aaacatatac
    46501 tattatcgga cgggaaacca agcatcatat ggatatcgta acgaagctga tcaatgaaca
    46561 gttagcagaa ttgaaacaat tatcaccaca aatggataat gaacaagcag caatcttgat
    46621 ggctgtcaat gcgctttcgg atcaattgaa gaaacaagaa agaatattgg agctggaaga
    46681 agaaacagca gaattaaaga aaaaaatgat caaatttaca gagcttgaaa atcgtgtgaa
    46741 acgcattgaa gcaatcgaga acgaagctcg ggaagtattg aaagaaaatg gtcaagcaga
    46801 tcataccatt aaaaatcatg tggaagcaca acagatttta aacgagaaac gaaaaggaca
    46861 aattaaacaa aaatcttcta attaagatcc ttttatcaaa ataagaaaaa tttaaaaaag
    46921 ttagaagaga aaggaacgta gcatgctgag tttgctgatt ttatttttat tgctaattgc
    46981 gtttttttct ggagcacgtc gcgggtttgc tttgcaaatc atattcgcga ttggatatgt
    47041 attgtcattt attgctgccc agcattttta caaaccatta gcaagtcatt tggaattata
    47101 cattccatac ccagctgtca ccccaacatc aaagttagca ttttttgatc aggtatttgc
    47161 ctttcaccta gatgaagctt tttatgcagg aactgctttt ctgattattt tgctaattgg
    47221 ctggctgctt acccgatttg tgggggtttt tgtccatgga ttgacgtatg tgccgatctt
    47281 gagacaggta gactggattg caggaggcat cctgtcacta atcatggctt acgttactat
    47341 atttttgatt ttgcagttac ttgcctttgt tccattagat gtggtccaaa atcaattcgg
    47401 cgagcatagt ttcgctcgtt ttatcgttga gagaacgcca tttcttacca acaagatgta
    47461 tgagctttgg gtaacgaata ttttgaatta aggaaaatag tgctggaaaa tatttcgttt
    47521 tttgtacaga gtagtttatt taagaaggct gcgtagcgta tgtccggcac agctcttttt
    47581 tcatagtgaa agataaggtg ataaaatgaa taaccgaatc cttgaaacat tggaatttga
    47641 aaaagtcaaa cagatggtca gacaatttgt agtgactgca caaggaaaag aagaactggc
    47701 agaattggta ccagtgagtg agaaacaaac gatcacaaac tggcttcaag aaactgagga
    47761 tggattgaaa gtgcaacgtc tgcgaggcgg gatccctata cctaaaattg aaaatatccg
    47821 tccccatatg aaacggattg agatcggagc agacttgaat ggagtggagc ttgcacaagt
    47881 ttccagagta ttgtctacga caagcgaatt gaatcgtttc attgatgatc tttctgacag
    47941 tgaaatcgaa tttgcacgtt tgtatatgtg ggcagatcag ttagtcacga tccctgtttt
    48001 gagccgccgt ttaaaggaag caatcgatga agacggacgc gtgactgatg acgcttctcc
    48061 tgagttaaag agcataagac agaacattcg gcgaagtgaa caagctgttc gtgaacagtt
    48121 agatgggatc gtccgtggga aaaatgcaaa gtatttaagt gatgcgatca tcaccatgcg
    48181 aaatgaccgc tacgttatcc cagtcaaaca agaataccgc ggtgtatttg gcggtgtagt
    48241 ccacgatcaa agtgcttcag gtcagacttt atttattgaa ccaaaacaag tggtggattt
    48301 gaataatcgt ttgcgtcaat accaaatcgc tgaacgaaat gagattcaac gtattttaag
    48361 tgaactttct gctgaacttg ttccccatcg tcaagaaatc atccacaata cttatgtgat
    48421 tggtaaaatg gatctgatga atgcaaaagc acgatttggt aaagaagtaa aagccatcgt
    48481 gccgggaatc agtgaagaca atcatgtcgt cttgaaacaa gcaagacatc cactgatcga
    48541 tcaggaaaaa gtagtttcta atgacatcac aatcggaaaa gactatcaag ccatcgtcat
    48601 tacaggacct aacacaggtg ggaaaacgat cacgttgaag actttaggtc tgttacaact
    48661 gatggggcaa gcaggattac cgattcctgc aggtgaagaa agtcaaatcg gtatttttga
    48721 ggaagtattt gcggatatag gagacgaaca gtcgattgag caaagtctat cgaccttttc
    48781 ttctcatatg acgaacactg tagatatttt atcaaaagtc aatgaaaaaa gtctggtatt
    48841 atttgacgag ctcggtgcag gaacagatcc gcaagaaggt gctgctctag caatcgcaat
    48901 cttagatgat cttggtaaaa agtctgctta tgtgatggca acaacgcatt atcctgaatt
    48961 gaaagtttat ggatataatc gggcaaatac gattaatgcc agcatggagt ttgatgtgga
    49021 tacattaagt ccaacgtatc gtttgctgat tggcgttcct ggacgaagca atgcgtttga
    49081 aatctctagc cgattaggtc ttgatacaga agttattgat gaagcgaagc agttgatgaa
    49141 tgatgagagc caagatttaa acgaaatgat cacagattta gagaatcgcc ggaaaatggc
    49201 agagaccgaa tatctggaaa tgcgtcattt tgtttctgag gcacaagaac ttcacgatga
    49261 tttgaaagaa gcttacagct atttctttga agaacgtgaa aaagaaatgg aaaaagcaaa
    49321 gaaaaaagca aatgaagtcg tgtcagaggc ggaagaaaaa gcagaaaaaa tcattgctga
    49381 tattcgtaaa atgcaacagc agattgggca aggaaatgtg aaagagcatc agttgatcga
    49441 tgcaaagacc caattagcaa atctacatca agaagaaact ttgaagaaaa ataaagtatt
    49501 gaagaaggcg aaagaacaaa aaacgttgaa accgggagac gaagtgttgg ttacgactta
    49561 cggccaaaga gggacgcttt tacgtaaaaa cgggaatcag tggcaagtag aaatcggtat
    49621 attaaaaatg aatgtgtccg aagacgagct gacgcctgtt gctcctcaaa aagagccgac
    49681 acaacgagtt atccatgctg tacgatctga atctagtagt cacgtgccga atcaattgga
    49741 ccttcgagga aaacgatacg aagaagcgct aagtgaggta gatcaatatt tggattctgc
    49801 cattctagct ggttatcctc aagtgactat tgtccacgga aaaggaacag gcgcacttcg
    49861 caagggaatt actgattatc ttaaaaacca tcggagcgtc aaaagctttg agtttgcacc
    49921 ggcaaaccaa ggcggaaatg gtgcgacaat tgttaaattt aagtaaagct tactaaaggt
    49981 aagcagatgg ttcgctatcc aagtatagaa atgctatact agtcatagat tttaaaaatg
    50041 gaggtctttg atatgtcaca agtaattaca gataagacat ttaatgaaga aacagataaa
    50101 ggacttgtat tgattgattt ttgggcaact tggtgtggtc catgtcgtat gcaagcaccg
    50161 attttggatc agttggaaca agaatatgat gaagaagaat tcagaattgc taaaatggat
    50221 gtggatgaaa atccagaaac tcctcaacaa ttcggtatca tgagcattcc aacattaatg
    50281 ttgaaaaaag atggtcaagt agtagaaaaa gctgttggtg ttcattcaaa agaacaacta
    50341 cgtcaaatga tcgatcaata tttataaaaa cttacagcaa aaataagctg agggtgggac
    50401 tgaatccagt tccgtcctcg gtttttttgc ggttgagtta aggttattca aattaatatt
    50461 ttttgagtat aattacgttg tcaggctgga ttgttttttt gacagacatg ctataataac
    50521 tttaattgaa tatgaagggg agtaccagat gaacgaacga atcaaaaaca aattagcttt
    50581 acttcctgat cagcccggct gttacttgat gaaagataaa aatggaacga tcatttatgt
    50641 cggcaaagcc aaaatattaa aaaatcgtgt ccgctcatat tttactggta gccataatac
    50701 gaaaacggaa cggcttgtta gtgaaatcga agactttgaa tacatcgtta cagaatcgaa
    50761 tatcgaagca ttgctcttag agatcaatct gataaagaaa aatgatccta aatacaacat
    50821 tatgttaaag gatgataaaa cctatccttt ccttaagata acgaatgaaa aatatccccg
    50881 tttggtgatt actcgtaagg tactaaaaga caaagcactg tattttggac catatcccga
    50941 tgtcggtgcg gcgaatgaga caaagaagat cctcgatcga ttatttcctc tgagaaaatg
    51001 caaacctagt cagacgaagg agccttgtct ttactatcat ttgggacaat gcctgtgtcc
    51061 ttattatttc gacgtagatc cgaaagtcta tacgaaaatc gttgatgaag tgaaaaactt
    51121 tttaaacgga ggacacgaaa aaatcgagtc agagatccat cagaaaatgg aaaaagctgc
    51181 tgaaaacatg gagtttgaaa aagctgcaga ataccgagac cagatccgtg ccattgagac
    51241 aatcatgact cgccaaaaaa tgacaaatac tgatttactg gatcgagatg tatttggtta
    51301 tgcgattgat aaaggatgga tgtgtgtcca agtgtttttc gtaagacaag gaaagctaat
    51361 tgaacgagat gtttcaatgt ttcctttcta taacgaagca gaagaagatt tcttgactta
    51421 cctcggtcag ttttatcagg aaaatgagca tttcattcct aaagaagtct tgattcctga
    51481 tacgatcgac aagcccagtg tagaagcttt gttagctacg aaagtgctgc aaccaaaacg
    51541 aggagaaaag aaaaaattag ttgaattggc gagtaagaat gcctcagttg ctttgaatga
    51601 acggtttgat ctgattgcca gaaaacagga acggacgatc ggagcagttg aacgtttagg
    51661 aaacgcgatg aatatcccga ccccaatacg tatcgagtct tttgataact ctaatatcat
    51721 ggggacgaat cctgtggctg cgatggtcgt attcattgat ggaaaaccgg caagaaaaga
    51781 atatcggaaa tataaaataa aaacagtcaa cggaccggat gattatgcat caatgagaga
    51841 agtcatctat cgcagatatt cgcgagtgat tcgcgaaggg ttgcctttac ctgatttgat
    51901 cttgatcgat ggaggaaaag gacaagtaga tgtggcaaaa gatgtcttag aaaatcaatt
    51961 aggaatcgat attcctattg ctggcatggt aaaaaacgat aaacataaaa caaatgagtt
    52021 gctattcggt acagatttgg ctgtagtacc gcttgagcga aattcaccag agtttttctt
    52081 actccagcga atccaagatg aagtccatcg attcgcaatc actttccatc ggcagctacg
    52141 cagtaaaaac agttttgctt cccgattaga tgaaattgaa gggttaggac caaaacgaaa
    52201 aaaaatgctg cttaaagagt tcaaatcgtt gaaaaatatc acagcagcca cgacagaaga
    52261 attacaagaa atcggactgc cgaaaaatgt cgcacaaaac gtatttgata aattacatca
    52321 ggaatgagga aagggcactt tacaaagaaa gtaaagtgtc ctatcatttt atgtacaaca
    52381 aaaagagcgt ttacgttttg ttggtaaata ataaatcgct tacgtctggt gtctaaggat
    52441 atatgtgatt tcttgaagaa ggagtgaaga aatgttagaa gtcaaggatc ttgttaaaac
    52501 ttttgggaac tacacagctg tcgatcatgt ctctttccaa atccccgatg gaaaaatcat
    52561 ggggctaatt ggccaaaacg gggctgggaa gacaacgact tttcgtttga tcttggattt
    52621 tttgacacaa gaccaaggag aagtgttatg gaatggccat catcttgggg agaaagatta
    52681 tgatgtcatc ggttatcttc cggaggaacg gggactttat ccgaaagtaa cgattcaaga
    52741 ccaactgctt tattttgcag aacttagagg gaaatcaaga aaagagattg aaccaaaaat
    52801 cgacttttgg atggaaaaat ttcaggtaaa agggaaaaag acggataaag taaaatcttt
    52861 gtctaaagga aatcagcaaa aagtccagct gatcgccacg ttaatccatg aacctaaatt
    52921 gatcattttg gatgagccat tcagcgggtt agatccggta aatgctgaat tgctaaaaga
    52981 tggaatattg gaattgaaaa aacatggttc atgtgtcatt ttttctagcc acaatatgga
    53041 taatgtagaa aaaatctgcg atcatttgat catgttgcga aacggaaaaa tggttttgaa
    53101 tggaaaagta catgagattc gtgaatcatt tggccgtacg aagttattct tggaatctgg
    53161 tttaagccaa caggaagtag aagaaatcga aggcgtgaaa aaagtgatcc ttcatgaaga
    53221 caatacgtta gagattacct tagaagatcc tgaagctggg aaagaaatct ttactcgtgc
    53281 gactcagttc ggctacattc ctatgtttaa ccagcaaccg ccaactttgg aagagatttt
    53341 caaattgaaa gcaggtgaaa tcgatgcgta agttttggat tattaccaaa gatgtctatt
    53401 taaaaaatgt taagtcgatt tctttcttga tcatgatatt agtccctttt atcatgctgg
    53461 gtatcattta tgtagcagga aactttgctc aacaaaatag tgatgtcaat aaaatcggcg
    53521 tattggctga taatgagcaa atcagtcagc aaatgagcca agtcaaaaca gatgattttg
    53581 agttcaaagc agttgattct gaagaaaaag cacaaaaaga gctttcggaa gaaaaaatcg
    53641 atgcgtattt agtagtctca actgagaatg ataagataaa tgggatgctt tatagcgaaa
    53701 attcattagg acaaagtaca caactactga tacaacaaca actgactggc ttgcaatcga
    53761 tgcttcgagc gagtcaatta ggcatttcac cagaagaagt agctagcttg agccaacaag
    53821 caagtttgac tcgacaaaaa gtcaattttg attcaaaagg aaaaatgaca gtcggagaag
    53881 ataactcgac agtccaatac gtcgtaagtt atgtagcaac gattgtcttg ttcattatta
    53941 ttttgacgta tgcgcagatc attgcacaag agatcgcttc tgaaaaaggc acgcggatca
    54001 tggaagtgat cctgtccagt acgactgcac aaaagcattt ttacggaaaa ttaacaggtg
    54061 ttttacttgt tgcattaacg caaatggcat tatacggtat tatttttggt ataggataca
    54121 gtcaattcaa agatatggaa atggtcaaaa atatattaga cggtatctca ttggataact
    54181 tgattggacc attcttgtgg tattctcttc tattcatgat ctttggcatt ttgatttttt
    54241 ctgttttagc agctttatgt ggctctttgg tcaacaaagc agaagataca gcaaaagcaa
    54301 ttttgccagt gacttatcta tctctaggcg gatacatgct tggattgata ctaggagctt
    54361 cagatccaaa caatatcgtt attcggatca cttcgtatat tccattctta tcttcatata
    54421 ttatgccgat tcgcttagca aatgagacag tcggtatggg tggagcattg atttccttgt
    54481 tggtacttgt agccgtaaca ttcttattga tgatcttgtc tgcaaacatg tacaaatcga
    54541 atgtactcgt ttatagcgaa ggcggattat ggagttcatt gaaacaatcg atttcaatta
    54601 tgaggaatga acgaaaaaaa gcataaaaca atcctaaaat acagaaggaa gctggacatc
    54661 tattgttccc agcttctttt tgtatagacc tattttattt attttactat attggatata
    54721 tattcattga aaatagtgta taacaacttt ataatattga gtataccaat ttttggaggc
    54781 gttttaatgg accgttattt agatttactt tcagaaaaat tcccctcaac ggaggatgtc
    54841 atcacggaaa tcatcaatct cgaagcaatt ttgcagcttc caaaaggaac agagttattt
    54901 ttgagtgata tacatggcga atttcctgct tttgatcata ttctgcgtat cggttcagga
    54961 aatcttaaag aaaagatcaa agaccttttt tctgaacaaa tgacggaaac ggatatcagc
    55021 caattcacta tttttacggc ttatccagaa tatgcattaa cgactgattg gtacaaagaa
    55081 caagataaat cgcagctgat ccatcatttg atcgatcttt tacggtttac gacagtcaaa
    55141 tatacccggt caaaagttcg aaaaggattg ccgaaagaat atagctatat cattgaggaa
    55201 ctcttgtata tcgatgaccg tatcaatgga aaaaaagact atgtaaaaaa aatcattgaa
    55261 caacttgttt tgatgaagga agaagaaaaa tttttaacga aacttgcaca gacgatccaa
    55321 aaatctgtca tcgatcattt gcatatcgtt ggagatattt ttgaccgagg aactcaagca
    55381 gccaaagtga tggatcgaat catggatttt tcttctgtag atatccaatg gggaaatcat
    55441 gatattttgt ggattggtgc gtattgcggc tctgaggcat gtttactgac acttttacgg
    55501 attgcagcac gctataatta tttatttgaa ttagagaaag aatatgggtt gaatttacgt
    55561 ccattgtttt cttttgctca tcaaacttat cagaagaatc cagtatttgc gcctaaaaac
    55621 agtaaaaatc tatccgaaag agagcaagaa gaattagaaa aaatccatca ggcactttct
    55681 atccttcaat tcaaatcaga acatcagtta ttggatcgtc gacctgaatt taaaatggac
    55741 gatcgtaaat tgctggaaaa aatcgactat gaagcatcaa cgattgattt agaaggtcag
    55801 ctctatgagt tgaaaggaac ttgttttcaa acgatccagc cagatgatcc aaaaaaattc
    55861 ttggaagagg aacaaaaagt gattgatagt ttgatgtatt cattccagca ctctttgaga
    55921 atgcaaaaac atatgacgtt tttgatcgaa aaagggggaa tgtatctcac gaacaatcag
    55981 catgtgctgt ttcatggctg tatacctgta gacgagaagg gacagctctt agcatttgaa
    56041 ttagaccaat cttatcgcgg aaaagaactg ctgggctttt ttgaaaaaca gataactgaa
    56101 agcgcaaaag atctgactgc aaaagaagat ttagcaaccg atttgatttg gtatgcgtgg
    56161 agtgggccat tttcgccttt attcggcaag agtaaaatgg cgacttttga acgttatttt
    56221 ctcacagagc ctcatacgca cgtcgagaaa agcaatcctt attatcactt gcgagatgaa
    56281 gagtggttca gtgaaaaaat tttagcagaa ttcgacacaa aagaagaagg gtcagcaatc
    56341 attaatgggc acacgccagt aaaagtaaaa aaaggggagt caccgatcaa agcaaatgga
    56401 aaagtatttg tcattgacgg aggtttatcc aaagcttatc aaaaaacgac aggaattgcc
    56461 ggttattcac tattatgcaa ttcttatggt ttccaaatcg tgacacatta tccgtttttg
    56521 cctattgaac aacaatttgc aaaaaaatcc gaccaaacaa atgtgaaaaa agtaatcgaa
    56581 cagcaactac cacgcaaact caatcgtgat acaacaaaag gtatggaact gcagcagcag
    56641 attacccagc tcaaaaggct gttggactat cgaaaggacg attgagaaga attccagtga
    56701 acattgttcc atagactgga gactgagaca aaagtcgtgt cgcagtctct ttttccggat
    56761 aaacggtgtt cttctgccaa ctcctcggtc acaagtcaca ctattcaaca aacatgaaaa
    56821 gctgtttttt gaaattgctc cttgtgactc agagttgaac ggcaggctca cgacctcttg
    56881 gtataaacgg tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgtg
    56941 aaaagccatt ttcacaaaat ttttcttaat actcgaaact aaacagcttt ttcacaaccc
    57001 cctcagaaag tctattaaaa ttcattcaca aagaaatcga ataagcgctg ttcagatgga
    57061 tgtacacggt gggtaagttc cggatgccat tgaacaccga ggattttatg catatcatct
    57121 ttgctttgaa ccgcttcaac gagtccatcg ttagaaaaag cgatggcttt taataaaggt
    57181 gaaagatctt tgactgcctg atgatggtaa gaattcacaa aatatggatc ggggagaagg
    57241 ttgcttaaca aactgtctga aacaatcttg acttcgtgag tcgtaaattg cggggcagtg
    57301 ggctgttgtt catgttttac tgaccacttt ggatataatg aaagatcttg ataaagtgta
    57361 ccttccaaaa cgacattcaa tagttggagt ccccggcaga ctgcaaaaat tggttttctt
    57421 tgtttcaatg cttccaagat cagtgcctgt tcaaattggt ctcgttgaat atttgtttcc
    57481 gttagctttg gatgaggatc ttccatgtaa agttgtggac tgacatcttg accacctgca
    57541 agaataagtt tgtcgatttg tccaatcagt tgaggagctg aatctggaga catgactggc
    57601 agaataagag gcaatccttg agcatctaaa actgcatcca cgaatccttg cggtgtatag
    57661 ctcacttgat ttccttggaa agtatctgtt gctcgaatca gttgatttcc ggcaatgccg
    57721 atgattggtt tcatttgtat tccccctaaa gtagacttat tgtaacaagg atttaaaaaa
    57781 aattaaacta tgtaagactt gcccctatac ttatctgttc ttgctgtgtt actatctgta
    57841 aagagaaatt tcgtgtgaaa ttcatgacga tagttgaaaa tattgcttaa tttgttataa
    57901 taaaaagtaa gcagaaataa aaaggttggg cgtaagcttc aaggatctag ttcttcaagg
    57961 ggtgagaagg acattttatt gaaggggcct gcctatacta agttatcttt agaggtacat
    58021 actttcaatg aaaaaagaaa gcatgtacct cttttttaaa tcgaaaggaa gtgaagcaag
    58081 tgttagaagc tttggaacaa atccgaaaag cagaagaaga aaatgaaaag cgtgctcaaa
    58141 cactgcggca gcagctgaag atctatgcaa cagaaaaaga gcaggaattg gaaacgatcc
    58201 aaacaaacta tcgacaacaa ctaaaacagt tggtggaaga aaaagaacaa tttgaaatac
    58261 aagaattaga aaaagaaaaa atgaaattga aagcagaagc agacaaggtg caagcaactt
    58321 tgaaagatca atatcaaaag catcagagtc aagcgatcgg tgcgatcatt gaaagggtga
    58381 aagaaactta tggccgtcac taagatggaa aaagtgaccc tcatttcaga taaaagaaat
    58441 caggagagga ttttacaagc agtacaagga atccaaaacg ttgaaatccg ggatctgtat
    58501 caaaatagaa caaacaacca gtgggtggag aagtattttc cagataccac gattattgat
    58561 aaagaagcaa aattaagcgc tttaggtaat cggttgaaag acatccaaga agctatccaa
    58621 ttcatacaac accacggcga tagccgtcaa aagaaactcc atttgaaacg tcaagaactt
    58681 tccttacaag atttggaagc caattattcc gaagaaaatt tcataaataa attgaaagaa
    58741 gtccttgatt taaaagaaaa gtgggaacaa ctaactgaag aacgtgatcg tttagaagaa
    58801 gaggaagaat ggcttcttca ttggcaacag ctggatattg ctccaagtat gtatgcaagt
    58861 aagacgacca tttttgagat ggggactgtg agtgcagcaa attttgaaag tttcaaggaa
    58921 gaactgagta agcttgatga cgtttatatg gaagaaatag attatacgcc aaaacaagtt
    58981 tatctttcgt atgttgcttt aaaaaaatca gttgctgtta tagaagaaat tgctgggaaa
    59041 tacgggttca ataaagaaac gtatccttat gaacaaaatc ctaaagaaaa actgcaagag
    59101 accaagcagc aattatccat tgttcacgag cagcaaaaga agataacgac agcgttaggt
    59161 cagtgcagtg gctatatcca agaatttgaa tgggtagaag aagtcacact tgccgttgca
    59221 gaacgagaaa aaataaaaga acggtttatc catgcgactt atctgatcgt tttgcaaggt
    59281 tgggtagatg cagaagaaaa acagaatttg ctgcatgtgt taaacgaaac cgtatcagaa
    59341 gaagatatat acgtcagttt cgaaacacca aactcagaag agattcagca ggaagtccct
    59401 actaaattga aaaaccatcc gcttgtcgaa ccttttgaat tgctgactga aatgtacagt
    59461 ctgccaaaat atgaagaagt agatccaaca ccttggatga caccatttta tcttgtcttc
    59521 ttcgggatga tggtcgcaga tgttggttat ggtttgctga tgctcattgg gacaatacta
    59581 gctcaaaaac tacttgttct accacgcggg atgaaacgtt tcgtaaaatt ctttgagatt
    59641 ctctcgatac catcgatcat ctggggattg atctacagtt catttttcgg acagtcatta
    59701 ccaaaagaac tgtttggcat ccgcttgcct ttcccaatcc tatctacgac ggatgacgtc
    59761 aatacgattt tgattttatc cgtgattttc ggtctgatac agattttggt tggattattt
    59821 gtggcagcaa aggaaaatat caggagaaaa gattacttga gtgctgtcag tgatggattt
    59881 gcctggcaag ggatcctaat tgggatcgtt attgcgttgg ttggtgccat gttgataaaa
    59941 aatacagcat ttgtttacct tggcgctggg ctatcgatca ttgctgcctt atgtatcttg
    60001 atcgttccga ttatccaaac gccgtctaaa gtcaaaggtg ctgccaaagg tgcgtataat
    60061 ctttacggac tgaccggcta tatcggtgat ttagtcagtt atacacgttt gatggcattg
    60121 ggtatttcag gcggaagtat tggagcggca ttcaatatgc tagttgcttt catgccgcca
    60181 gctgctcgat tcagtgtagg gatccttttg atcatcgctt tacacgcact gaatatgttt
    60241 ttgacactgc taagtgccta tgtccatggc gcacgattgc agtatgtcga attttttggg
    60301 aagttttata caggaggcgg acgtgccttt gatccgctga aaacggcgga aaaatacgtc
    60361 aacatcaatc acaagaaaaa aaacaataaa taattggagg atttttatat aatgatggat
    60421 tacttaatta gtcaaaatgg tggaatggta tttgcggtat tagcgatggc aacagcgacg
    60481 attttttcag ggatcggttc agctaaaggt gttggaatga caggtgaggc agcagcagca
    60541 ttgacaacaa gtcaacccga aaaattcggg caggctctga ttctgcaatt gcttccaggc
    60601 acgcaaggtt tgtatggatt cgttattgcc tttttgattt ttatcaactt aggaaatgac
    60661 atgtcagttg tacaaggact gaactttcta ggtgcttctc tgccgattgc ttttacaggc
    60721 ttgttttcag gtattgccca aggaaaagtc gcagcggcag gtattcaaat tttagcgaaa
    60781 aaacctgaac atgctacaaa aggaatcatt tttgctgcga tggttgaaac atacgcgatt
    60841 ttaggtttcg ttatttcctt cctattagtg ttgaatgcct aagcataaag gaggaaaagc
    60901 agatgaacgc cattgaaaaa atcatctctc agatgaacga agcagcagag caggaaagag
    60961 cggcgttaga acaagaagag cgaatgaaga tcgatcaaaa ctttgaacaa aaacgtacgc
    61021 aagttgaaac agaacatcaa aaacaaaaag aaaaacaaat cgaattactc gaaaaaaaat
    61081 accgtcagct aaggaatcgc cagcaagtag aagtacgaca agaaaatttg aatgcgaagc
    61141 aggaattttt aagacgattg tttgcagatg cggtaactga aatggaaaat tgggatgaat
    61201 ctgaacaaat ccagtttatc aaaaatgcat tgtattcatt acctttgaca ggaaaagtag
    61261 cattcattgc tggagaaaaa tcagcagcct atctttctca gacgttgttg gatgaatgga
    61321 acaatgaact tccctttatg atggttttaa gtgatgaaac tgttgctgat caagcgggtt
    61381 ttctgataaa cgatcaagga gttcagtata attttctttt cagcagcctt gtacaagata
    61441 tccaaggaac gatgagtttt gagattgcca atcaattatt cgaataagga gggatcagtg
    61501 tatggaatac cacgaactaa atcccttgat tcgcggaaga gagcttgaac ttttgtccaa
    61561 tgagacattt gaacggatga ttcaaacaaa ttctgtcgaa gcacttggtg aaatattgaa
    61621 atccacgatt tacagtccat atatttatga cggatatgaa tatgacttcg aacagaatct
    61681 tttaaaggag cagagccgtc tatttcgctg gttaaaggaa tcagcaccgg agcctgaaat
    61741 cgtttggatc tatacgatgc gttatacttt ccataatctg aaggttttga caaaagctga
    61801 gatgacaaat caaaatctgg accatttgta tatcgacgat ggattttatt cattagaaac
    61861 cttgaaggat gccattcata cgcaagtttc aaatgaactt cctgaaagca ttatggacag
    61921 tatacgagaa gtacgtgatt attttgaaga gtctaccatt cttcagggaa ttgacgtgat
    61981 ttatgatcga cagtttttga cagagcagcg acggcttgcc gataagctag gatatcaaga
    62041 attgctgaca gaagtcattg cttttattga cttgaccaat atcacaacga tggctcgagg
    62101 aatattgcag aaaagaacat atgggttcat gacgacggta ctttccagct cgggaagtat
    62161 cgaaaaagaa gtatttttga actttgtaga taaagatatg gaagattaca cgaattttct
    62221 attagagaca gattatgctg attttctgcg ccctgtcatc cgtgagggaa atattgatct
    62281 cgtaaagctt gaacagttga aagatgatta tctaagttca ttgtatcaag aagcacaaac
    62341 ccaggctttc ggaccactgc cactactagc ctttttgaac gcaaaagagg tagaaagcaa
    62401 aaaccttcgt ttactggtta tcggcaaaag aagccatttc gaatcagaaa caatcagaaa
    62461 gcgggtgaga caagtctatg acgcataaga tcggtgtagt tggcgacaaa gattctgttt
    62521 tgccattcaa attgtttggc tttgatgttc gttatggtac aaccaagcaa accgttcgtc
    62581 aggcaattga agaaatggca aagaatgagt atggcgtgat ttatgtcaca gagcaatgtg
    62641 cagcattgag cccagaaacg atcgaacgtt acaaggaaca aatgatacct gctatcgtat
    62701 tgattcccaa tcatcaagga tcattaggga tagggctgga agaaattcaa aaaaacgtag
    62761 aaaaagcagt aggtcaaaat atcttatagt atgaaaagga gatagaaatt ttgcaaattg
    62821 gaaaaatcat aaaagtctcc ggacctcttg taatggctga gaacatgtct gatgccagta
    62881 tccaagacat gtgtctagtg ggagatctag gagttatcgg agaaattatc gagatgcgtg
    62941 gcgatgtggc gtctattcaa gtatatgaag agacttctgg aattggtcca ggcgaaccgg
    63001 ttcgctctac tggtgaagct ttatctgttg aattaggacc agggatcatt tcacaaatgt
    63061 ttgacggaat ccaacggcca ttagatacct ttatggaaat cacacaaagt aatttcttag
    63121 ggcgcggagt tcaattgccc gcattggacc atgagaaaaa atggtggttc gaaccaacag
    63181 tagaagccgg agaaacggtg agtgctggag atgttatcgg gatcgtagaa gaaacaaaag
    63241 ttataaaaca taaaatcatg gtgccaaatg ggataaaagg aacgatcaaa acaatcgaaa
    63301 aaggttcatt cactattgat gaaacagtat gtgtcattga aaccgaaaat ggtgacaaaa
    63361 atttgacgat gcttcaaaaa tggccagtaa gacgtagtcg gccaatcaaa gaaaaattaa
    63421 acccggatgc acccatgatc actggacagc gagtgattga tacattcttc ccagtgacaa
    63481 aaggaggagc agcagctgta cctggtcctt ttggtgcagg gaaaacagtc gttcagcatc
    63541 aaattgcaaa atgggccgat gtggacatgg ttgtctatgt gggatgtggc gagcgtggaa
    63601 atgagatgac ggatgtttta aatgaattcc ctgaattgat tgaccctaat acaggagaat
    63661 cgttgatgga acgtacggta ttgattgcta atacatcaaa catgccagta gcagctcgag
    63721 aagcttctat ctatacggga atcacaattg cggaatattt ccgtgacatg ggttatgacg
    63781 ttgctatcat ggcagactcc acttcacgat gggcagaagc acttcgtgag atgagcggac
    63841 gtttggaaga aatgcctggt gatgaaggtt atccagctta tcttggttca cggcttgcgg
    63901 aatactatga acgatctgga agagtcattg cattaggatc agaaggtcgc gaaggaagta
    63961 taaccgcaat cagtgctgta tccccgtctg gaggggatat ttcggaacca gtcacacaaa
    64021 atacattgcg ggtcgtaaaa gtattctggg gtcttgattc cagtttagcc caaaaaagac
    64081 attttccttc gatcgattgg atacaaagct attctcttta ttcaacagaa gtagggaagt
    64141 atatggatca tatccttcaa gctgactggg catccatggt caccgagggc atgcgtattt
    64201 tgcaggaaga acagcagctg aatgaaatcg tgcgtttggt agggattgat tccctttcag
    64261 ataatgaccg tctgacatta gaagtggcaa aatccattcg tgaagattat ttgcagcaaa
    64321 atgcttttga tgatgtcgat acattcactt caagagagaa acaattcaaa atgttgaaga
    64381 tgatcttgac ctttggtgaa gaaggacgcc gtgcgttgtc gttaggtgct tatttaagtg
    64441 agatcatgga cggtaccgta tcgattcgtg aaaggatcgg acgaagcaaa tatatcccgg
    64501 aaacagaatt agaaaaacta gatcaaatta ttggtgaaat caagcaaacg atgcaaacga
    64561 tcgtttcaga aggaggcatg agcaatgatt aaagaatatc gtacgatcgg tgaagtcgtc
    64621 ggtccattga tggcggttga aaaagttgct ggtgtcaaat atgaagaatt aatcgaagtc
    64681 cgtatgcaaa atggcgagat tcgtcgtgga caagtattgg aagtccaaga agataaagca
    64741 atggtccaaa tattcgaagg aacaagtggt atcaatttac gtgactcttc tgtacgattt
    64801 ttaggccatc ctttagaact aggtgtatcg gaagacatga tcggtcgagt attcgatggt
    64861 ttgggacgac cgaaagataa cggaccagag atcctgcctg aaaagcattt ggatattaac
    64921 ggagaagtaa tcaatccagt agctcgggat tatccagatg agtttatcca aacaggtatc
    64981 tctgcaatcg atcatttgaa tacattagtt cgtgggcaaa aattaccagt attttctggc
    65041 tctggtcttc ctcataaaga attagctgct cagatcgcgc gacaagcaac ggtactcgat
    65101 tcatcagatg atttcgccgt agtctttgct gctattggaa tcacttttga agaagctgaa
    65161 tttttcatgg aagattttcg tcaaacgggc gcaatcgacc gttctgtcat gtttatgaat
    65221 ttagcaaacg accctgcaat cgaacgtatc gctactcctc gtatggcttt gactgctgca
    65281 gaatatcttg cttatgaaaa gggaatgcat gttttggtta tcatgacaga catgaccaac
    65341 tatgcagagg cattgcgaga gatttctgca gcacggcgag aagttccagg aagaagagga
    65401 tatcctgggt atctttacac gaacttagct actttattcg aacgagcagg aagaatccgc
    65461 ggactaaaag gatcggttac tcaaattccg attctaacaa tgccagaaga cgataaaact
    65521 catccaatcc ctgacttgac tggttatatt acagaaggac agatcatctt gactagagag
    65581 ctttacaaga gtgggattca gccaccaatt gatgtactcc cgtctctttc gcggttaaaa
    65641 gataagggaa ctggacccgg aaagacaaga gaagaccatg cagctacgat gaatcagctt
    65701 tttgcagcct atgcacaagg aaaacaggca aaagaattag ccgtagtttt aggtgaatct
    65761 gctttatctg atgtagacaa gatctatgcg aagtttgctg agcggtttga aaaagaatat
    65821 gtcaatcaag gattctacac gaaccgttcg attactgaaa cacttgatct agggtgggaa
    65881 ctgctatcga tgttgccaag aaccgaatta aaacgaatca aagacgacat gctggacaaa
    65941 tatctgccag aagggaagtg agttctgatg gcacgattga atgtgaatcc gacccgcatg
    66001 gaattgactc gattgaaaaa acagttgaca actgccacaa gagggcataa attattaaaa
    66061 gataagcaag atgaactgat gcgtcaattc atcctgttga ttcgaaagaa caaccagctg
    66121 cgtcaagaaa tggaagagtc tatgacagaa gcaatgtctg attttgtatt ggcaaatgct
    66181 tcgatcacgg aacctttcat cgaagaatta tttgttttgc cggcggaaaa cgttgatttg
    66241 tctatcgtag acaaaaatat catgagtgta aaagtacctg tgatgaattt tgaatatgat
    66301 gaacagctga cagacacacc tttggaatac gggtatttga attccagtgc cgaactggat
    66361 cggtcaatcg atcggtttac taccctgctt ccaaaacttt tggaactgac agaaatcgaa
    66421 aaaacttgtc aactgatggc gagtgaaatc gaaaagacac gtcggcgagt caatgcatta
    66481 gaatatatga cgatccctca attagaagaa acgatctatt atattcgtat gaagctggaa
    66541 gaaaacgagc gcgcagaagt aacaaggttg atcaaagtaa aaaatatggg taccactgac
    66601 taagtggtat ctttttttaa aagaggaaaa cgatgattaa acaaagcaaa caaataaaga
    66661 aacgtttgcc ggctgttcag cttctcgcat taggattttt tctcctgatt ttagttggcg
    66721 gcggcctact taccctacca ttttttagta atagtgggca tgggacaaat tttatcgatg
    66781 cgcttttcac tgcaacttct gctgtctgtg taacgggatt gacaacattg aatacagcag
    66841 agcattggaa cagtgctggt caatttttga tcatgctttt gattgagatc ggcggtcttg
    66901 gttttatgat ggttccgatt ctatgctttg cattgataaa gaagaaagtc agtctcagca
    66961 cacgtattat attaaaagaa gcgctgaatc tagaagaagt atcaggtgtg atgaagctca
    67021 tgctttacat cctaaaattg gcctttgtga tccaattgat tggtacggtt gctttatctt
    67081 ttgtatttgt gcctgaattt ggctggttga aaggtatctg gtacagtttg ttccatgcaa
    67141 tctctagttt ttgtaatgca gggtttgatt tgttaggaga cagtttagcc aatcaccagc
    67201 aaaatgttta tttgatcatg gtggtatctg ctttgatcat ttctggtggg ttaggcttca
    67261 tcgtatggcg tgatttactg gaatatcatc agaaaaagaa gatgacgatt cattcaaaaa
    67321 tcgcattaac cgttacaggt acccttttat taggcggatt cgttgtgttc tttttcacag
    67381 agcgcaatgg ggcaacgcta gtggaaggga atatgtttca acgattggca aacacctttt
    67441 ttatgagtgt gacacctaga acggctggat attattcagt tgattacctc catatgagcc
    67501 atgcaggtct gattttaacg atgtttttga tgtacatcgg cggaacatct gggtcgacgg
    67561 ccggcggatt gaaaacaact acgttaggtg tgttgctgat ccagatgcgt tcgatgttga
    67621 aaggacgtac gagagcggaa gcatttggcc gtaccatccg acaaggcgca gtgttgcggg
    67681 cacttacttt attttttgtt acgttgacgt tgtgtgtagt cgccatcatg attttatcgg
    67741 tgactgaaac gatacctaaa acttctggca tcgaatatat tgcttttgag gtcttctctg
    67801 cgtttggtac agtaggtctt acgatgggat tgacgccaga cttgactgca atagggaaat
    67861 tgatcattat agcgcttatg tacattggac gagttggtgt attgactgtg gtcttctctc
    67921 tgatgacaaa agcacaaaga acacaatcaa aatacaaata tccagaagaa agtgtcatga
    67981 ttggataatt tcatcttctg acagaaacct agtgatttag taaaataaga aaataaaata
    68041 atttttcttg cttcttggat actttaagtg caaaatgttc gtttattttt tgaggcacta
    68101 cccgttgttg aacctcgggt agtgcctctt ttttattgaa aggaatcaat aagatttgat
    68161 tcctttattt atcaataggt tataattcat atttttttat tttttctttt acgatactta
    68221 gtccagaagc taaaatttca aggttattag aggataggga aattcgaacg aatgcatctg
    68281 gttgcgcacg tgtagtaaag cgtctggaat gataaagtcg gataccgtta gcaagaaagt
    68341 cattctcaat tatcttaggg tcaatctcag gatcaactgg aagaattcga tagtaaggga
    68401 cacgattcgt tggtttttct actttgaaaa gagaatcaaa aagctgattg gctctttttg
    68461 taagacttaa tttagtttct aagatcctat ttgcttcatt tgaatggagg atttgagtga
    68521 tgacttccac atctaatcca gaagttttca catttatatt aaaaattgct tgttctatct
    68581 tgctttggac atgtactgga actacaagat aagcaactcg caatccagaa caaataaatt
    68641 ttgtcattcc agctaagtag attgtttggt taggtaataa attttggaaa ggaggaatga
    68701 tcgtatgttg atagtaagtt gttaaaaatg aatggatatc atcttcaata acccatagac
    68761 cttctttttc aatcacttcg gctaattgct ctcgtctttt gtgagagatt tgaaacccta
    68821 taggattatt acaagaaggc ataagaaaga caccatgaat cttctttttt ctacattcct
    68881 gaatcaatat atcaggtcgc attccttgct cgtcaaaatc aattggaacg atctctaaat
    68941 gatataactg agccaattca atgaaattag cgtatgtata tcggtctgtt gctattctat
    69001 cacctggaga gaaaagtgca gaaagtgtga tagccaatcc attttgaaca ccggaaacaa
    69061 tagatagaga ttctaaggac ggaatgactc cttgagtttt taaccaattt gctgcagtag
    69121 tcaattgaaa atttgtgcct ttgggatctt ggtaattaag caaaccaaca agatttgggt
    69181 tattactagt tgattgaata aacgggacaa cgaatttatt acattcttca aaagaactaa
    69241 ccagaccaaa atcaatgata tgttcggtta cttcattggt agagatggtg atggactcaa
    69301 agacattggg agaaataaat gtgccacttc caatattcgt atacagcaaa cctttctcaa
    69361 ttccatattt ataagccttg ccaacggtag taaaatttaa atctaaataa tcagctagct
    69421 ctctttggga gggtaactga gtgtttttct gtaatttatt ctttaaaata tcttgttcta
    69481 attgttgaat caacgatcga taataaggac gcttcaattt ttgtttgtct ggtcgccaag
    69541 ttaacgggta attgtcataa gaattaatag gcattttctc cactccttaa aattgtatac
    69601 catacaattt taccattgat tgtattgatt ttagaagtta atcttttgtg aggagggaat
    69661 tgtctatgaa aattattaat tttgaggaag tagtagcttc ttttagtttt gaagaagcga
    69721 ttcaagtaat gaaaaaatgt ttttttgatt atgaaagtgg taaaatcagc caaaatcctc
    69781 gattggtgga aattttacct gacggaaaag gcaaaaatat gtttgcgatg atgcctgctt
    69841 atttggggga gaacagatat tttggcacaa aagtcattac cgcttttccg gataatcatc
    69901 agtatcattt accttctcat ttaggagaga ttttcttgtt tgatgctcaa aacggactac
    69961 ccaaagcatt gataaacgca aatgcagtca cctggattcg aacagctgct gtatctgcgc
    70021 tggcaacaga ttacttagca aatccgcatg cagaaacact tgctttaatt ggagctggtc
    70081 aacaagcatt gtcgcatttg actgcgattt ctaccattcg tcccatcact acagtgtttg
    70141 tttacgatat tttagaagaa agacgaaata cttttatcgc taaagctaaa aaacagtatc
    70201 ctaaaataac gtttataaat gcaatatcag tagaagatgc agtacgtcca gcggaaatca
    70261 tttgtacgtt gacctctagt aaagaggcat ttcttcaaaa agagtgggta agggaagacg
    70321 cacatatcaa tgctgtgggc acatttactc ctgatacaag agagataagt acatcgttga
    70381 tggaaacttc tcaaatctat gtagatgatt actcagctgc cttaacagaa agcggggacc
    70441 tgcttatagc catggcagaa ggagatttag aggaatcttg tattgttggt acattaggcg
    70501 aattagtttc tgagaaaaaa acattttata aaggagaatc gaggccgacg attttcgacg
    70561 cagttggtct agctattgaa gatctttgtt gtgcagaata tatttataac aaattagaga
    70621 aaggggcttt aaaatgaact tagattatta cgtagttgat gcatttgcag atgaggtgtt
    70681 caaaggaaat ccagcagcgg tttatgtgct agaagaatgg ctgccagaag gtacgatgca
    70741 aaaaattgcc attgaaaaca atttatctga aacagcattt acagtgaaga aaaaccaaga
    70801 atttgagctt agatggttta cgccagatcg agaaatcgat ctttgtggtc acgcgacatt
    70861 agcaacagca tttgttttat ttaactatta caaaatacct gatgaaacga ttaaattttc
    70921 tactcaaagc ggtaatctat ttgtgacaag aattaaagat tattattaca tggattttcc
    70981 tagtattatg ccgaaaaaag tgccgatatt gtctgaatat gaagaagcga ttggggctaa
    71041 gattaaagaa gcctacttag cacgtgattt atttttcgta ttagaagatg aaaaaacggt
    71101 ggctaaattg cagccagatt ttacagctat caaaaatttt gaattaggaa taggagtcat
    71161 cgtgacagca gaaagtgtgc aaaaagactt tgtttctaga accttctttc caaaattaac
    71221 aatcaatgaa gatccagtat gtggatcagc acattctaat cttattcctt attgggcaga
    71281 aagaatgaat aaaacaaaat tgtcagctta tcaaatgtca tcaaggggcg gggatctaga
    71341 atgtgaatta aaagaagatc gtgtgataat aggaggaaaa gcagttttgt tttctaaagg
    71401 tacctcgttt atttgatttc tttcaaatga attaaaaata aattggtgga gagtggcaac
    71461 cttatagcta caatggttgt taaaaaaaga cgcaaacttt ttcaatttaa tgaaaagttt
    71521 gcgtctcatt ttaattattg gtgtttgttt tttattcaat caagagtaaa atgccccata
    71581 ctaactatcc tcggatgact tcgattttat aaccatcagg gtcaatgaca aagtagtaag
    71641 aaggcgcagt gccaggtaat ccttttaagt cagtaatctc aagaccagca gctttatgtt
    71701 gctcgtgtaa tttttctaga tcatcagctg ctatagcgat atgaccatag ccgtctccta
    71761 gatcatacgc accatgatca tagttgtaag tcaactctaa ttcatagtca tccccaggaa
    71821 gtgtcaaata aacaagtgta aatttgtttt ctggaaaatc acggcggcgg ctttcttcaa
    71881 aaccaaatgc cttttgataa aattcgattg atgcttcaag atctttcact cgaacacatg
    71941 tgtgagccat tttcatagat tcatctctcc ttttcctttt actcaatcat aacaaaaaga
    72001 agtaaggaaa tagttgattt gtgcttgttc atgagaaatt tctcatgtaa aatggataga
    72061 aaataaaact gttaaggtgg aaactattca tggataaacc aatttttggt gaaaaaaagc
    72121 aatttgctga ttatcaaacc cgttatgcag catatattgt catagaaaga gatcagcaga
    72181 ttgcagtaat cgaggctcca aatggtgctt tttttcttcc tggcggggaa attgaaggag
    72241 aagagacgaa agaagaagcg attgtccgtg agctgataga agaaatggga attgtggcag
    72301 aaatttcttc ttatctggga gaagctgatg agtattttta ctcgaattat cgtgcaactt
    72361 attattataa tccaggatat ttctttgttg ctgattcttg gaagcgtata ggagaaccaa
    72421 ctgaaaagac caataaaatt tggtgggtga gccctcaaga agcgcttgtg aaattgaaac
    72481 gtggtagcca ccgatgggca gtcgagagat ggatcgaaaa aaataaaaac tgaaagaaag
    72541 cgagtagatc agctttctct cagttttttt atttattaca gtacatattt tttgattgct
    72601 tcagctacac cgtgctcgtc gtttgatgaa gtgatgacat ttgctgcttc tttgacaaga
    72661 gaaacggcat ttcccattgc tactcctaga ccagcatatt caatcatgga taagtcgttc
    72721 tcgttatctc cgatagccat gatttcatct tgatcaatac caaggtgctg tgcgagattc
    72781 gcaactgccg cacctttact tgcttcttta tttagtactt cgaagtaata gggcgcactt
    72841 ttgaccgttg tgtatttatc acggaaagtt tgcggtaaac gcgcaattgc tgcatctaaa
    72901 atttctggtt cgtcgatcat catcattttg acgatgttca tgtctggtgt catttcttca
    72961 ggtgttcgat attttagcgg catcttgact aaacttgctt cgtggatcgt ataagcgctg
    73021 atatctcgat taggcgtgta gatcgctttg tcatcgatcg aatggagatg actgccgaca
    73081 cggcgtgcca ttacttcgat ctctaggaaa tcttcatgtg tcagtccgtg acgggcgatg
    73141 attttacctg atttcgtttg ttgtacgagt gccccgttat aagtaataac gtaatcatta
    73201 tcttgaaaaa ggttcaactc gtttaactgt tcctggacac ctggtaaggg acggccagtg
    73261 cataaaacga tcgaaacacc ttttgcaaca gcagcggcaa tcgcttcttt tacttctttt
    73321 gttacttctc ttttctcatt taataaagta ccatcgatgt cgatagcgac tagtttgata
    73381 gacataattt cctccaatat attttaattt atttcaatca atgcgccatt acggatatgg
    73441 ctggcaaatt cttgataagt ttcgtcaaat aaatcataat gatcacgcaa ggacggatca
    73501 accatttctt ttggaaagaa aaatcgctca tctccttgtt cttgtcccgc taatgcagca
    73561 acaagctgac taacctgtga taattctatc aaagttccgt catttcgcaa aatctcgatt
    73621 tgtgtgcgat gtctgccttg ttctgggcga taaaaatcat aaggtagatc gtagctagaa
    73681 ttcacagcag tgtaataaac aggattatat ccgacctttt ctactaacaa agtgagttct
    73741 tggactaatt ttgaatcccg gttgccagaa aaagtagcag atttcagtgg tttacgattc
    73801 aaaaaacgtt tagctaaatc atttaaaata ggatcagcag attcagacca ttgagtaaag
    73861 taagtgccca agaccccatc atcaagtttg aggtattctt ctaaagtaaa gcttccgtca
    73921 agaaatggca gaagtaattg agaatggagt tcaaaactgc tggcatcttc ttgatacaac
    73981 tcgtgtgcgc gatgaagcag atgctccaaa attacttcca taccacggga aacaggatgg
    74041 aagtacactt gcacatacat ttgatatcgg ctaacgatat aatcttccac tgcatgcatg
    74101 ccactcatgg aaaaagcgat cccgccttca taaggacgaa tcacacgtaa tattcgggta
    74161 agatcaaatg ttccatattc tgttccagtg aaataagcat cccgaagcaa atagtccatt
    74221 cgatctgcat cgatctgact agaaatcatt tggacaactt gtgggttggg gtaagttttt
    74281 tggatcacac tagctacctt ttcaggaaaa ccttcttcta ctcggttaag aatctgatac
    74341 acttctgttt ctggagaagt gatgatctct acagtgatgg cttcatgatt cgtatggaag
    74401 atatgttcaa atgtatgaga gtaaggacca tgaccgacat catgcaacag tgccgcacat
    74461 aaagtcacca gccgttcctg atcatcccag cctccgttgc ctattttttc ttttgaaaaa
    74521 tttcgagaaa agatatcgca gattcgtctt gaaatctcat aaacgcctaa tgaatgagta
    74581 aaacggctat gttctgctcc gtgaaaagtg aaagaagaag tgcctaattg tttaatgcgt
    74641 cgtagacgtt ggacttcttt cgaattgatc aaatctaaga ttacttgatg ctggacatgg
    74701 atatagttat ggactggatc acgaaaaact ttttccatag gcagcatttg atatttataa
    74761 ggggttgtca taatgtagct cctttatgtt attacgttgt tccattctct ggatttggtt
    74821 gttccattgc tccagctgga tttctttttt tagccagtcg gtagaatcct gtaaatcact
    74881 tgcagaatac agcttttcaa aagcttttgc aaatgcttct ttgacttctt ttacaaaaag
    74941 gggttggtca agcagttctt caagtgttgc cattgtagca ggatccactg caggatagcc
    75001 atttgtacca aagtcttctt ttaaagcaga ttgataaaat cgcttcatga cttgcccacg
    75061 tttttcctga ttaccgttga cacttaagta catcataaca gaaatcccat ttttgatccg
    75121 acgctgagcg ataccggcaa attttttgcc atggatgctt aaatcataag ttccaggaca
    75181 ataagaatgg gtgatttcga atgcttgtat cggtgccttt ggaaaagcgt atttagtcaa
    75241 taggagcatt tgctcgtaag cgtcatctat ggttattttt tttgtgtcac tttgggggaa
    75301 aatcaaagaa atattcaaaa ttccttcatc tgatacgatc cctaatccac ctgaatttct
    75361 gatcactgga gcgtaacctg catcttccag tgtttggatc ccgtcactta gaaaaggagt
    75421 tcgaacatcc ttcataccta agatgactgt gcagtcatat tgccagaaat gtaaaaagat
    75481 ttgctggtgt tctttagaat attccgttaa tatatctgtt aatgcaaaag gggaaaagtc
    75541 gtttttttga taaatgtgct gatctagtcg aatcgcaggg ttcattcaac cggctccttt
    75601 gtataaattc atattttcta caatattata ctctaaaatc aaagagttgt tttggaaaaa
    75661 aggttttctg taaaaatgga caagttggtt gacaaaacaa aagaaactag gaacaatgta
    75721 gctatgagaa gtaaaggaga atgaataatg gaattatcac aaggaacacc gatttcaatc
    75781 aaattgcgta caaaagtaaa acagcaaggg gaagtgcaag atttttattt tgatttgaaa
    75841 gggcaaatgg tgacaattgg cgatacgctg tacatacgtt ataaagagat tcaggaggag
    75901 acgggcgatg agattcctgt aacgatcaaa ttagttccag atggtcatgt acagctgatc
    75961 cgtgcaggag aaatgcggat gcgtttgaaa tttggctata aagaacggtt agaaacatcc
    76021 tatcgaacac catacggtat gatccagatt gctactttta cgaaagaact gcatgttagt
    76081 ttgaaagacc gtcccacagc agggaaggtt cgaatcgatt atgatctgtt catgggaccg
    76141 gaaaaaatcg gcgaatatta tttgaccttg gattttacag cgtaaatata aaagaaaagt
    76201 ttgatttttt gtgtctgatt ttgtatgata aggagtagac tgtgaaagga cgtgtcctga
    76261 ttggaaatta gtgtatttga aggtgcaaac aaaagcgaat tatcaatgat cgaagtagca
    76321 cacgcgatct tagaacaacg tggcgatgtc atggattttt ctgatttagc taaccagatc
    76381 caaaactatc ttgggaaatc agacagtgaa attcgtgatt cactcgcaca attttatact
    76441 gacttgaata ttgacggcag ctttatctca ttaggggata atcgttgggg cttgcgttca
    76501 tggtatgcta tcgattcgat cgatgaagaa gtaaaccatg gaatggacga agaggatgaa
    76561 gatactccac gtcgccgtaa acgcaagaaa gtcaacgcct ttatcaatga tgatgaagac
    76621 gcgatcgatt acaatgacga tgacccagaa gatacagatc tgacagaaga agatgacgat
    76681 gatctgtttg atgacgatga tgatgaagat gaagaaatcg ctgcttataa ttctgacttg
    76741 caagaaatcg gagcagatga cccgacagat gatgaagaag acttgccagg aaatatcgaa
    76801 gaagatttaa gtatcataga cgaagacgat gatgatgaag attatgaaga ggaagaattt
    76861 tctgactctg aaaaagaata aacattattt tcttacgaga ggttgtgaca gagacgatca
    76921 gcctatcaga ataaggaggt gtgacacgat ttttgtcaca ccttcttttt tgtatataaa
    76981 aatcccaagt aaatacataa aaaataaaaa aattgaaact tttagcgcac cttgtacgtc
    77041 atattaagtg aggcagaaag gagtggagaa tgatttttac tggatataag aaaaaacggc
    77101 agatcgaaaa ataccgtcac ctgctgaatg gactcatcga aactgattat caaaaaatgt
    77161 tccgtatcac gatgaattac gtacatgata aagaagaggc cttagatgtg atgcaagata
    77221 gttttcataa agccctgaac tattttgaaa aagaaaaaga gatcgagcat tttagtgcat
    77281 ggttttatcg gatattgatc cgcacggcat tagatagttg gcgcagacaa aaaaggacgc
    77341 ctgtggactt atttgaaatt caagatatcc cccaacagtt acctttagaa acttccgttg
    77401 cagagctcca tatgatttta gataaaatag acagtccgga aaaagagatt ctgatcctct
    77461 acttttttga aggatttcgt ttgaaagaaa ttgcgactat cttggatatg aatgaaaaca
    77521 cagttaaaac gaaaatgtac cgctcattga atgctttacg tcaaatccta gaatgaagga
    77581 gagaagagtg ccatgtattc ccaaaaagaa aatttaaaaa aactaaagaa aacttataaa
    77641 gaacaagcaa ttcccaaagg gcttaaagag gagatccgcc agcgttttat tatcgaagag
    77701 caatcattta taaaagcaaa gcggagaaag agacgtctcc aagggttcgg agtatctttg
    77761 gctatcgtaa tgattacaac aagtagcctt ctttttaata gtcaagttcg aagctttgca
    77821 gaagatttac ccatcttagg atcagtcatt gaattgatct taggcgaacg ctttactgat
    77881 cgatctgaaa aaatcgatat tcaggtaccg aagatcaata cacaaaatga gaaagaaaat
    77941 aaaacaattc atggattaaa tcaaaaatac tttcgcgaag gacaagcaga ttttgaaaaa
    78001 gctgaaaaag aatatggaaa ttttgaaacg gatcattacc aagttttggg agattatcag
    78061 aaaatcgtag acgataaccg gtttctcgtg attgaaaggc agatcaccca aacagcagca
    78121 gatagccatg ttgaaaaaag atacgacaca atcgacaaga aaaacagtgt ccagctctca
    78181 cttccacttt tattcaaaga tgacacctat ctatctgttt tgacaaaaga agtcaaacgg
    78241 cagatggccg aacaagtcaa ggaagatcca tctaagtact attggactga gcaagatatt
    78301 caagaaggga cgatagaaaa accaacactt gttacgccta cacgaagttt ttatttgaac
    78361 aaagagcatc aattagtttt gactttttct caatacgaaa ttgctcctgg ttatatgggt
    78421 acaccagaat ttgtcattcc taagtccgtg acaaaaacga ttttggcatc ggaagattat
    78481 ttggatcatt agacgagaag tagttgcgac tagcagtttc aattttcaag taagtacaag
    78541 taaataataa gaagagaaaa agagaaagaa gagatatagt gaaaagaaat tatttagtta
    78601 tcagtattat tgctttatcc gtgcttttgt ttttcgaaat tacttcggtg gcctccttga
    78661 tcaccgaagt aaaaggacaa acacactctt cggagcattc gtcacaatct ttcaaacaat
    78721 cagaacaatc aaccattaaa agccaatcaa ctgaaacagc taacgtcaaa gaagccattc
    78781 aagaatcagc ggaaaaggta caaagtcagt catcacaatc aacacaagac agtacaaaaa
    78841 cgagccgaga tccggctgtc aaaagcgtcg caatcagctt tgatgatgga ccaggagcga
    78901 ccacaacacc gcagcttctg cgaatcttaa aagaaaaaaa cgtgcatgcc acttttttcg
    78961 tcttaggaga aaatacggcg cagcatcctg aaatcgtgaa gcagacagct gaagcagggc
    79021 acgagattgg caatcacaca tacgatcatc agaatctggc cactctttct gcccagtcga
    79081 tgacggagga agtgacgaaa gcagacactg agatcaaaaa agtcactggc aaaaccccca
    79141 cttttgttcg tccgccctat ggttctgtca cgaatgtagg agcaacgatc atccagcgac
    79201 cgatcatcga atggtctgtt gattcagaag attggaagac aagaaatcct gatttgattt
    79261 tgcagaagat ccaagcaaca gtatacgatg gggcaattat tttattccat gatatctatc
    79321 ctgaaacgat tcgtgccgtt cctcaagtga tcgattatct gaaagagcaa gggtatcgca
    79381 tcacgacagt tggggattta ttagggcatc caacggctgt cgagaactat tatggcagaa
    79441 acgatcatcg gccagttcag taagtgagac aagtatcttt aataaataac acattttaat
    79501 aagtagttga acacataact accttacttg caaaggctta acaatatcta tacaggtaca
    79561 acaaaaaact gtccaccaat tttctttggc ggacagtttt cacttaaaaa taaagaagca
    79621 actattcgta aattatgcta aaatagcagt agaacgcgtc ctgagggaat cgaacccccg
    79681 tctcaagaac cggaatctta cgtgatatcc actacactaa ggacgcaagc actgggataa
    79741 ttgtaactaa acagataaaa aattacaagg ggattggaca aaaaaatgaa atttgagcaa
    79801 aatttttcac aaaaacagca gcagacacag aaactagcca tgacgcaaca gttgcaacag
    79861 tccatccaag ttttacaata taacagtgag gagctgttgg cattcgttga gaatcaagca
    79921 atggaaaatc cattggtgga agttgttgag ccggaatggc agccagatta cataaaagct
    79981 tcttcatctt cttatgaagg agaagagaca aattacctaa atcagattcc tgatacaaaa
    80041 gggtctttat ttgattcatt gatcgaacaa gtccatttga attaccgaga tacttttttg
    80101 aggaaaatcg ttctttatct tgtagaatac atcgatttga acggattttt gacgattagt
    80161 ttagaagaag ccggaaaaga gattggagct acgcctatcc aaatgctcga tgcgttgact
    80221 ctgattcagc aattagaacc agctggagta ggtgcacgta gtttgcaaga atgtctcatg
    80281 cttcaaacag aacgagatga ttatgcgccg gaattagctt atatcgtgtt ggaagaatgt
    80341 tttgaggaac tggtggagcg aaaatggaaa gaaatcgcac aacgtttttc tgttgatcta
    80401 catgctgttc agcagatatt cgactattta caaacgttga gtccaagccc tggccggatt
    80461 ttcgaccgta gcagcgaatt gtacattatt cctgatgtcc gggtattagt ggacgacgat
    80521 aaaaatgtac aagttatctc aaaccgaaaa aatcagccaa atatacgctt tcaagagagt
    80581 tacttcaaac aaatgtcaca acaagcagat aaagaaactg aaaattattt aaaagaacgg
    80641 aaacaggaat tcgaatggtt gaagaaaacg atcctacaac gtggggatac aattttgcgg
    80701 gttgctcaag tcattgtttc ccggcaaaaa gctttcttta tcgacaagga acgtccaatc
    80761 aagcctctta cgttaaagga agttgcaact gagatagatg tgcatgaatc cacggtcagt
    80821 cgtgcagtca acgggaaata tttggaaaca gacttcggtg tatttgaatt aaaaaaattt
    80881 ttcactacac gaattcctac gaatagtaca gaacagacag aagacctttc agcagataca
    80941 gcgaagaaaa agctgcagga attagtcgat caagaagaca aaaacaagcc gttgtctgac
    81001 cagaaattgg ttgaattgct gaaaaaagat gagatagcga tctcaagacg aacagtagca
    81061 aaatatcgtg atttattagg aatcccgagt tcatcaaaaa gaaaacgtta tgataactaa
    81121 tcagtcaaaa gactagaaaa agtatttcac tttttctagt ctttttagtt gaaaaacgag
    81181 agcaaaactg ttagacttac agtcgtgagg ttgagatttc cctttattga tgtgaaattc
    81241 gaatagttaa tttctttttt tatcgtatat gggtcgtttt aagtctacat tggacgtaaa
    81301 gtgtccaact aaggagatcg ctatgctgga tgaaataaaa atgattgaat ctgttgcacc
    81361 agatattatc gaagtgttgc aagaacgcta taaaatttta cgaaatatct attggatgca
    81421 gccgattgga cgtcgaagtt tatcggaaag tatggggatc acagaacgag tattgcgaac
    81481 agaaacagat cttttgaaaa atctgaattt gatcgacacc tcaaaaagcg gtatgacgct
    81541 gacaactaag ggcgaagaag tttatcaaag ccttgaaaac ttcatggatc agcttttagg
    81601 tacgcatcaa accgaacaac agttggcaga atattttggt aaccaacgct gtatcgttgt
    81661 ttcaggaaac agcgaagagc agaccaaagt ggctgatgca ttcggcgaag cgctgagcga
    81721 agccctagac cgactacttc cagaaggcga gaatatcatc gctgtgatgg gaggaactac
    81781 tatggctgtg gtagccgaac aattgtctaa tctggaaaat aagaaacggc ataacctgtt
    81841 tgtccctgca agaggcggga ttggtgaagc gataactgta caggcaaatt ctgtcagtgc
    81901 aagaatggct gctaaagcaa acggtaacca ccgtgcactt tatgttccgg aacaattaag
    81961 tctggcaact tacaattctt tactcaatga gccatctatc caagaagtct taaacttgat
    82021 tagtgaagcg aattgtgtta ttcatagtat tgggcgtgca ttacacatgg cagcacgtcg
    82081 taagatgact gaaaaagaat tagtcatgct gaaacaagca aatgctgttg cggaatcttt
    82141 tggctacttt ttcaatgaaa aaggtgaagt cgtttataag gtccctagaa tcggcataga
    82201 attgcaagat ttggaaaaag tcccgatcat catggcaatc gcgggcggaa aatcaaaagc
    82261 taaagcaatt cgagcttata tgaaaaatgc accaaaacaa acgtggctca tcactgatga
    82321 agctgctgca aatgagattt taaaaggggt aaccctttaa aataaatatt tttttgattt
    82381 tcataaggag gaaatcttaa atgacagtta aagtaggtat taatggtttt ggacgtattg
    82441 gacgtctagc attccgtcgt atccaagatg tagatggaat cgaagtagta gcaatcaacg
    82501 acttgacaga tgctaaaatg ttggcacact tgttaaaata cgacacaact caaggacgtt
    82561 tcaacggaac agttgaagtt catgaaggtt cattcaacgt aaacggaaaa gaagttaaag
    82621 tattagctaa ccgcaaccca gaagaattac catggggcga actaggcgta gatatcgttc
    82681 tagaatgtac tggtttcttc acttctaaat cagcagctga aaaacattta acagctggtg
    82741 ctaaacgcgt tgttatctct gctcctggcg gaaacgatgt tccaacaatc gtttataaca
    82801 caaaccacga aacattaact ggtaaagaaa cagttatctc aggtgcttca tgtactacta
    82861 actgtttagc tcctatggct aaaacattga acgacaaatt tggtgttgtt gaaggattaa
    82921 tgacaactat ccacgcttac acaggtgacc aaatgactct agacggacct catcctaaag
    82981 gtgacttccg ccgtgcacgc gctgctgctg caaacatcgt tcctaactca acaggtgctg
    83041 ctaaagctat cggtttagta attcctgaat tgaacggtaa attagacgga gctgctcaac
    83101 gtgttcctgt accaacaggt tcattaacag aattagtaac agttcttgaa aaagaagtaa
    83161 ctgttgacga aatcaatgca gcaatgaaag aagcttcaaa cgaatcttac ggatacaaca
    83221 cagacgaaat cgtttcttca gatatcgttg gtatgactta cggttcatta tttgatgcta
    83281 cacaaactaa agtaatgaca gttggcgaca aacaattagt taaaactgtt gcttggtacg
    83341 acaacgaaat gtcatacact gcacaattag tacgtacttt agaatacttc gctaacttat
    83401 aagatagaca aacgtacaag tgtaaattat agacatgtac atttaaaagc ggggaagcaa
    83461 tcgcgcttct tccgcttttt ttgataataa gtttattcag gaggaaataa aatggctaag
    83521 aaaacagtga aagatatcga tttaaaagac aaaaaagttc ttgtccgtgt tgacttcaac
    83581 gttcctttga aagacggcgt gatcactgac gacactcgta tcaaagcagc attgccaaca
    83641 atcaactacg ttctagaaca aggcggaaaa gcaatccttt tctctcacct tggacgtgta
    83701 aaaacagaag aagataaaga aggaaaatct ttagctccag ttgcaaaacg tctaggcgaa
    83761 ttattaggta aagaagtaac attcgtacct gaaactcgcg gagaacaatt agaagaagca
    83821 atccgcaaca tgaatgacgg cgacgttgtc gtattcgaaa atacacgatt tgaagatatt
    83881 gacggtaaaa aagaaagcaa aaatgataca gaactaggta aatactgggc ttcattaggc
    83941 gatgtatttg ttaacgatgc tttcggtaca gctcaccgtg cacatgcttc taacgtaggt
    84001 atcgcttcaa ctggtatccc aacagttgct ggattcttga tggaaaaaga aatcaagttc
    84061 atcggtgaag cagtagaaga accaaaacga ccaatgattg caatccttgg tggcgcaaaa
    84121 gtttctgata aaatcggcgt aatcgaaaac ttgattccta aagcagataa aatcttgatc
    84181 ggtggcggaa tgacttacac attctacgaa gcaaaaggaa tcaagatcgg taactctcta
    84241 gtagaagctg ataaagtgga actagcaaaa gaattaatcg aaaaagcagg cgacaaactt
    84301 gtcttgccaa tcgacaatgt ctgtgcacca gaattttcaa atgatgttga aacacaagta
    84361 atcgaaggag acattcctga tggtttgatg gctttagaca tcggcccagc atcagtaaaa
    84421 ttatttgctg atacattaca aggtgcaaaa acagttgttt ggaacggacc tatgggtgta
    84481 tttgaaatga gtaactttgc taaaggtaca atcggtgttt gtgaagcaat cgctaactta
    84541 gaaggcgcaa caacaatcat cggtggcgga gactcagctg cagcagcaga acaattagga
    84601 tttgctgaca aattcacaca catctcaaca ggtggtggcg caagcttgga attgcttgaa
    84661 ggtaaagaat taccaggact agcagcaatc aacgataaat aaacgaccaa gtttgctcaa
    84721 ttctgacgag taatcgatca aaaggtgaag ggagttttca tgactcccta gccatttttc
    84781 aataaattaa ggagtgtgtt cctcaatgcg taaacctatt atcgcaggta actggaaaat
    84841 gaacaaaact gcatcagaag caaaagaatt tgctgaagca gtaaaaaaca aaatcccttc
    84901 aaatgacaaa gttgattcag tcatcggatc tcctgcatta ttcttacaag aattaatgac
    84961 atcagctgaa ggtacagaac taaaaatctc agcacaaaac tgctactggg aaaactcagg
    85021 tgcgttcact ggtgaaactt caccagcagc tcttgctgat ctaggtgttc attatgtgat
    85081 catcggacat tcagaacgtc gtgaatattt ccatgaaaca gacgaagaca tcaataaaaa
    85141 agcaaaagct atctttgcaa atggtatgac accaatccta tgctgcggcg aatctttaga
    85201 aacctatgaa gcaggcaaaa ctgctgaatg gatcgaagga caaattacag ctggtttagc
    85261 tgatctttca gctgaacaag tgtcaaacat ggttattgct tatgaaccaa tctgggcaat
    85321 cggtactggt aaatcagctg acgcacaaat cgctgacgaa atttgtggag ttgtacgtca
    85381 aacagttgaa aaactttatg gaaaagaagt atcagaagca gttcgtatcc aatacggcgg
    85441 ttctgtaaaa ccagaaaata ttgctgaata catggcaaaa gaaaatgttg acggtgcttt
    85501 agtcggtggc gcaagcttgc aagcagattc atttttgtca ttgttagacg ctgtaaaata
    85561 attgttgaaa atttgcgaaa aatgcaagaa atgtttgcac taatgagcaa aattaactaa
    85621 aatcgtatat gagggaaatc ccttaggaaa aaacaaactc aaaggagaga caaaacatgt
    85681 caattattac tgatgtttac gctcgcgaga tcttagactc acgtggtaac ccaacaatcg
    85741 aagtagaagt atacacagaa agcggagctt ttggccgcgg aatggttcct tcaggtgctt
    85801 caactggtga atacgaagca gttgaattac gtgacggaga caaagctcgt tatggcggta
    85861 aaggtgtaac taaagctgtc gacaacgtaa acaacatcat tgctgaagca atcattggct
    85921 acgatgttcg tgaccaaatg gctatcgaca aagctatgat cgctttagac ggaactccta
    85981 acaaaggtaa attaggtgcg aacgctattt taggtgtttc tatcgctgtt gcacgtgcag
    86041 ctgctgacta cctagaagta cctttatacc actacctagg cggattcaac acaaaagtat
    86101 tgccaacacc aatgatgaac atcatcaacg gcggatcaca tgctgataac tcaatcgact
    86161 tccaagaatt catgatcatg cctgttggcg ctccaacatt caaagaagct ctacgtatgg
    86221 gtgctgaagt attccacgca ttagcttcaa tcttgaaagc tcgcggatta gcaacttctg
    86281 ttggtgacga aggtggattt gctccaaacc ttggttcaaa cgaagaaggt tttgaagtaa
    86341 tcatcgaagc aatcgaaaaa gctggctatg tacctggtaa agacgttgtt cttgctatgg
    86401 atgctgcttc ttcagaattc tacgacaaag aaaaaggtgt ttacgtacta gctgactcag
    86461 gcgaaggcga aaaaacaact gacgaaatga tcaaattcta cgaagaatta gtttctaaat
    86521 atccaatcat ctcaatcgaa gatggattag acgaaaacga ctgggacgga ttcaagaaat
    86581 taactgacgt attaggcgac aaagttcaat tagttggtga cgacttgttc gtaacaaaca
    86641 ctcaaaaatt atctgaaggt atcgaaaaag gaattgctaa ctcaatcctt atcaaagtga
    86701 accaaatcgg tacattaaca gaaactttcg aagctatcga aatggctaaa gaagctggct
    86761 acacagcagt tgtatctcac cgttctggtg aaacagaaga ttcaacaatc tctgatatcg
    86821 ctgttgcaac aaatgctggc caaatcaaaa ctggttctct atcacgtact gaccgtattg
    86881 ctaaatacaa ccaattacta cgtatcgaag accaacttgg tgaagttgca gaatacaaag
    86941 gtttgaaatc tttctacaac ttaaaaaaca aataattctt ttctaatgaa gatacatgat
    87001 cgactattga aagatagtcg agtatgatca cttagttaag taatcgaact ctctacttgc
    87061 tgaaatatca gcaggtagag a
//
LOCUS       DAJSMK010000003        84834 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.003, whole genome shotgun sequence.
ACCESSION   DAJSMK010000003 DAJSMK010000000
VERSION     DAJSMK010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 84834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 84834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..84834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.003"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..171
                     /locus_tag="ON488_000174"
     CDS             <1..171
                     /locus_tag="ON488_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCR3230396.1"
                     /translation="SLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFK
                     IEYTKKRQRLAY"
     gene            406..642
                     /locus_tag="ON488_000175"
     CDS             406..642
                     /locus_tag="ON488_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230397.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="ON488_000176"
     CDS             649..2601
                     /locus_tag="ON488_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCR3230398.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="ON488_000177"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="ON488_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCR3230399.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3532..4572
                     /locus_tag="ON488_000178"
     CDS             3532..4572
                     /locus_tag="ON488_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCR3230400.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4670..4858
                     /locus_tag="ON488_000179"
     CDS             4670..4858
                     /locus_tag="ON488_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCR3230401.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4916..5269)
                     /locus_tag="ON488_000180"
     CDS             complement(4916..5269)
                     /locus_tag="ON488_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3230402.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5800..6222
                     /locus_tag="ON488_000181"
     CDS             5800..6222
                     /locus_tag="ON488_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCR3230403.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6219..6449
                     /locus_tag="ON488_000182"
     CDS             6219..6449
                     /locus_tag="ON488_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3230404.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6947..7147
                     /locus_tag="ON488_000183"
     CDS             6947..7147
                     /locus_tag="ON488_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCR3230405.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7174..8367
                     /locus_tag="ON488_000184"
     CDS             7174..8367
                     /locus_tag="ON488_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3230406.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="ON488_000185"
     CDS             complement(8435..10000)
                     /gene="guaA"
                     /locus_tag="ON488_000185"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCR3230407.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10059..10982)
                     /locus_tag="ON488_000186"
     CDS             complement(10059..10982)
                     /locus_tag="ON488_000186"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCR3230408.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11178..11783
                     /locus_tag="ON488_000187"
     CDS             11178..11783
                     /locus_tag="ON488_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3230409.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12091..13107
                     /locus_tag="ON488_000188"
     CDS             12091..13107
                     /locus_tag="ON488_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCR3230410.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13248..14549
                     /locus_tag="ON488_000189"
     CDS             13248..14549
                     /locus_tag="ON488_000189"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCR3230411.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14595..15257
                     /gene="deoC"
                     /locus_tag="ON488_000190"
     CDS             14595..15257
                     /gene="deoC"
                     /locus_tag="ON488_000190"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCR3230412.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15278..15676
                     /locus_tag="ON488_000191"
     CDS             15278..15676
                     /locus_tag="ON488_000191"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCR3230413.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15742..16824
                     /locus_tag="ON488_000192"
     CDS             15742..16824
                     /locus_tag="ON488_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3230414.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17036..18598
                     /locus_tag="ON488_000193"
     CDS             17036..18598
                     /locus_tag="ON488_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230415.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18591..19724
                     /locus_tag="ON488_000194"
     CDS             18591..19724
                     /locus_tag="ON488_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230416.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19724..20680
                     /locus_tag="ON488_000195"
     CDS             19724..20680
                     /locus_tag="ON488_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230417.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20779..21945
                     /gene="deoB"
                     /locus_tag="ON488_000196"
     CDS             20779..21945
                     /gene="deoB"
                     /locus_tag="ON488_000196"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCR3230418.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            21969..22787
                     /locus_tag="ON488_000197"
     CDS             21969..22787
                     /locus_tag="ON488_000197"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCR3230419.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22804..23511
                     /gene="deoD"
                     /locus_tag="ON488_000198"
     CDS             22804..23511
                     /gene="deoD"
                     /locus_tag="ON488_000198"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCR3230420.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="ON488_000199"
     CDS             complement(23809..24495)
                     /gene="gpmA"
                     /locus_tag="ON488_000199"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCR3230421.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(24667..25248)
                     /locus_tag="ON488_000200"
     CDS             complement(24667..25248)
                     /locus_tag="ON488_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3230422.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="ON488_000201"
     CDS             complement(25381..26064)
                     /gene="rpiA"
                     /locus_tag="ON488_000201"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HCR3230423.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            26383..26796
                     /gene="rpsL"
                     /locus_tag="ON488_000202"
     CDS             26383..26796
                     /gene="rpsL"
                     /locus_tag="ON488_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HCR3230424.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            26880..27350
                     /gene="rpsG"
                     /locus_tag="ON488_000203"
     CDS             26880..27350
                     /gene="rpsG"
                     /locus_tag="ON488_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HCR3230425.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            27444..29531
                     /gene="fusA"
                     /locus_tag="ON488_000204"
     CDS             27444..29531
                     /gene="fusA"
                     /locus_tag="ON488_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCR3230426.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            29703..30890
                     /gene="tuf"
                     /locus_tag="ON488_000205"
     CDS             29703..30890
                     /gene="tuf"
                     /locus_tag="ON488_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCR3230427.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            31297..31605
                     /gene="rpsJ"
                     /locus_tag="ON488_000206"
     CDS             31297..31605
                     /gene="rpsJ"
                     /locus_tag="ON488_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HCR3230428.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            31636..32265
                     /gene="rplC"
                     /locus_tag="ON488_000207"
     CDS             31636..32265
                     /gene="rplC"
                     /locus_tag="ON488_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HCR3230429.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            32293..32916
                     /gene="rplD"
                     /locus_tag="ON488_000208"
     CDS             32293..32916
                     /gene="rplD"
                     /locus_tag="ON488_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HCR3230430.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            32916..33206
                     /gene="rplW"
                     /locus_tag="ON488_000209"
     CDS             32916..33206
                     /gene="rplW"
                     /locus_tag="ON488_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HCR3230431.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            33245..34078
                     /gene="rplB"
                     /locus_tag="ON488_000210"
     CDS             33245..34078
                     /gene="rplB"
                     /locus_tag="ON488_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HCR3230432.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            34121..34399
                     /gene="rpsS"
                     /locus_tag="ON488_000211"
     CDS             34121..34399
                     /gene="rpsS"
                     /locus_tag="ON488_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HCR3230433.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            34422..34769
                     /gene="rplV"
                     /locus_tag="ON488_000212"
     CDS             34422..34769
                     /gene="rplV"
                     /locus_tag="ON488_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HCR3230434.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            34783..35439
                     /gene="rpsC"
                     /locus_tag="ON488_000213"
     CDS             34783..35439
                     /gene="rpsC"
                     /locus_tag="ON488_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HCR3230435.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            35442..35876
                     /gene="rplP"
                     /locus_tag="ON488_000214"
     CDS             35442..35876
                     /gene="rplP"
                     /locus_tag="ON488_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HCR3230436.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            35866..36054
                     /gene="rpmC"
                     /locus_tag="ON488_000215"
     CDS             35866..36054
                     /gene="rpmC"
                     /locus_tag="ON488_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HCR3230437.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            36079..36345
                     /gene="rpsQ"
                     /locus_tag="ON488_000216"
     CDS             36079..36345
                     /gene="rpsQ"
                     /locus_tag="ON488_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HCR3230438.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            36403..36771
                     /gene="rplN"
                     /locus_tag="ON488_000217"
     CDS             36403..36771
                     /gene="rplN"
                     /locus_tag="ON488_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HCR3230439.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            36808..37116
                     /gene="rplX"
                     /locus_tag="ON488_000218"
     CDS             36808..37116
                     /gene="rplX"
                     /locus_tag="ON488_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HCR3230440.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            37144..37683
                     /gene="rplE"
                     /locus_tag="ON488_000219"
     CDS             37144..37683
                     /gene="rplE"
                     /locus_tag="ON488_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HCR3230441.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            37702..37887
                     /locus_tag="ON488_000220"
     CDS             37702..37887
                     /locus_tag="ON488_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HCR3230442.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            37923..38321
                     /gene="rpsH"
                     /locus_tag="ON488_000221"
     CDS             37923..38321
                     /gene="rpsH"
                     /locus_tag="ON488_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HCR3230443.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            38353..38889
                     /gene="rplF"
                     /locus_tag="ON488_000222"
     CDS             38353..38889
                     /gene="rplF"
                     /locus_tag="ON488_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HCR3230444.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            39050..39406
                     /gene="rplR"
                     /locus_tag="ON488_000223"
     CDS             39050..39406
                     /gene="rplR"
                     /locus_tag="ON488_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HCR3230445.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            39427..39927
                     /gene="rpsE"
                     /locus_tag="ON488_000224"
     CDS             39427..39927
                     /gene="rpsE"
                     /locus_tag="ON488_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HCR3230446.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            39942..40121
                     /gene="rpmD"
                     /locus_tag="ON488_000225"
     CDS             39942..40121
                     /gene="rpmD"
                     /locus_tag="ON488_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HCR3230447.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            40165..40605
                     /gene="rplO"
                     /locus_tag="ON488_000226"
     CDS             40165..40605
                     /gene="rplO"
                     /locus_tag="ON488_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HCR3230448.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            40605..41900
                     /gene="secY"
                     /locus_tag="ON488_000227"
     CDS             40605..41900
                     /gene="secY"
                     /locus_tag="ON488_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HCR3230449.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            41962..42609
                     /locus_tag="ON488_000228"
     CDS             41962..42609
                     /locus_tag="ON488_000228"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HCR3230450.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            42800..43018
                     /gene="infA"
                     /locus_tag="ON488_000229"
     CDS             42800..43018
                     /gene="infA"
                     /locus_tag="ON488_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HCR3230451.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            43051..43167
                     /gene="rpmJ"
                     /locus_tag="ON488_000230"
     CDS             43051..43167
                     /gene="rpmJ"
                     /locus_tag="ON488_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HCR3230452.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            43185..43550
                     /gene="rpsM"
                     /locus_tag="ON488_000231"
     CDS             43185..43550
                     /gene="rpsM"
                     /locus_tag="ON488_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HCR3230453.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            43578..43967
                     /gene="rpsK"
                     /locus_tag="ON488_000232"
     CDS             43578..43967
                     /gene="rpsK"
                     /locus_tag="ON488_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HCR3230454.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            44047..44985
                     /locus_tag="ON488_000233"
     CDS             44047..44985
                     /locus_tag="ON488_000233"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HCR3230455.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            45013..45393
                     /gene="rplQ"
                     /locus_tag="ON488_000234"
     CDS             45013..45393
                     /gene="rplQ"
                     /locus_tag="ON488_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HCR3230456.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            45665..46504
                     /locus_tag="ON488_000235"
     CDS             45665..46504
                     /locus_tag="ON488_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCR3230457.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            46480..47349
                     /locus_tag="ON488_000236"
     CDS             46480..47349
                     /locus_tag="ON488_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCR3230458.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            47339..48136
                     /locus_tag="ON488_000237"
     CDS             47339..48136
                     /locus_tag="ON488_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCR3230459.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            48339..49085
                     /gene="truA"
                     /locus_tag="ON488_000238"
     CDS             48339..49085
                     /gene="truA"
                     /locus_tag="ON488_000238"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HCR3230460.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(49418..52087)
                     /locus_tag="ON488_000239"
     CDS             complement(49418..52087)
                     /locus_tag="ON488_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HCR3230461.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(52325..52513)
                     /locus_tag="ON488_000240"
     CDS             complement(52325..52513)
                     /locus_tag="ON488_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HCR3230462.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            52783..53145
                     /locus_tag="ON488_000241"
     CDS             52783..53145
                     /locus_tag="ON488_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCR3230463.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            53197..54879
                     /locus_tag="ON488_000242"
     CDS             53197..54879
                     /locus_tag="ON488_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HCR3230464.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            54996..57032
                     /gene="recG"
                     /locus_tag="ON488_000243"
     CDS             54996..57032
                     /gene="recG"
                     /locus_tag="ON488_000243"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HCR3230465.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            57081..58082
                     /gene="plsX"
                     /locus_tag="ON488_000244"
     CDS             57081..58082
                     /gene="plsX"
                     /locus_tag="ON488_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HCR3230466.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            58204..58446
                     /gene="acpP"
                     /locus_tag="ON488_000245"
     CDS             58204..58446
                     /gene="acpP"
                     /locus_tag="ON488_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCR3230467.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            58714..59718
                     /locus_tag="ON488_000246"
     CDS             58714..59718
                     /locus_tag="ON488_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230468.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            59719..60663
                     /locus_tag="ON488_000247"
     CDS             59719..60663
                     /locus_tag="ON488_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230469.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            60663..61625
                     /locus_tag="ON488_000248"
     CDS             60663..61625
                     /locus_tag="ON488_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230470.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            61652..62566
                     /locus_tag="ON488_000249"
     CDS             61652..62566
                     /locus_tag="ON488_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230471.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            62592..64373
                     /locus_tag="ON488_000250"
     CDS             62592..64373
                     /locus_tag="ON488_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3230472.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            64721..65407
                     /locus_tag="ON488_000251"
     CDS             64721..65407
                     /locus_tag="ON488_000251"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HCR3230473.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            65427..69008
                     /gene="smc"
                     /locus_tag="ON488_000252"
     CDS             65427..69008
                     /gene="smc"
                     /locus_tag="ON488_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HCR3230474.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            69017..69826
                     /locus_tag="ON488_000253"
     CDS             69017..69826
                     /locus_tag="ON488_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3230475.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            69837..70835
                     /gene="ftsY"
                     /locus_tag="ON488_000254"
     CDS             69837..70835
                     /gene="ftsY"
                     /locus_tag="ON488_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HCR3230476.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            71022..73289
                     /gene="gshAB"
                     /locus_tag="ON488_000255"
     CDS             71022..73289
                     /gene="gshAB"
                     /locus_tag="ON488_000255"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HCR3230477.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(73378..73830)
                     /locus_tag="ON488_000256"
     CDS             complement(73378..73830)
                     /locus_tag="ON488_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HCR3230478.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            73980..74930
                     /locus_tag="ON488_000257"
     CDS             73980..74930
                     /locus_tag="ON488_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCR3230479.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            74923..75882
                     /locus_tag="ON488_000258"
     CDS             74923..75882
                     /locus_tag="ON488_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HCR3230480.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            75879..76634
                     /locus_tag="ON488_000259"
     CDS             75879..76634
                     /locus_tag="ON488_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3230481.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            76657..77610
                     /locus_tag="ON488_000260"
     CDS             76657..77610
                     /locus_tag="ON488_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3230482.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(78254..78550)
                     /locus_tag="ON488_000261"
     CDS             complement(78254..78550)
                     /locus_tag="ON488_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HCR3230483.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            78905..79261
                     /locus_tag="ON488_000262"
     CDS             78905..79261
                     /locus_tag="ON488_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCR3230484.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            79271..80170
                     /locus_tag="ON488_000263"
     CDS             79271..80170
                     /locus_tag="ON488_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HCR3230485.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            80687..81418
                     /locus_tag="ON488_000264"
     CDS             80687..81418
                     /locus_tag="ON488_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCR3230486.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            81563..83590
                     /locus_tag="ON488_000265"
     CDS             81563..83590
                     /locus_tag="ON488_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCR3230487.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            83698..84795
                     /locus_tag="ON488_000266"
     CDS             83698..84795
                     /locus_tag="ON488_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HCR3230488.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT        27860 a        15171 c        18004 g        23799 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 tcctgcccgt tagttgaata agcaattttt tctataagtt atattatcat aataccacaa
     3301 aatcacaaat tttcattcaa ttatcatttt caattgcatt ttataaatca ttttgtatgt
     3361 aatttggtat gtaagttaaa atgaaaaaag tagtccattt tgaagtacat tttgtcattt
     3421 tgtactccaa aactgaacta cttacttgca tatatacgcc tttatagtgg agtactacat
     3481 ttacgagatt cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact
     3541 tcaataaatg gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg
     3601 caaaatgagt ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga
     3661 aaaaagattg aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa
     3721 cagagagaaa tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga
     3781 tattacgtgg attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg
     3841 gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct
     3901 acagtcattt atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg
     3961 ccgccaaatc ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt
     4021 ggaatgcagt atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca
     4081 gttatggaag ggatacgcta tggttgcgaa caaggattat atggttggaa tgtgacggat
     4141 tgtaaaatct gttttaagta cggtttatac tatagccctg ttagtactcc agcagatttt
     4201 cggatgctta ctcctattgt actggagcaa gcctttagaa aagctggaac agaattgtta
     4261 gagccatatc ttagttttaa agtttatgca ccacaggaat atctttcacg ggcatataac
     4321 gatgctccca aatattgtgc aaatatcgta aatactcaac tgaaaaataa tgaggtcatt
     4381 attattggag aaattcctgc tcgatgtatt caagattatc gcaatgattt aacttttttt
     4441 acaaatgggc ttagtgtttg tttagcagag ctaaaaggat atcaggttac cactggcgaa
     4501 cctgtttgcc agacccgtcg tctaaatagt cggatagata aagtaagata tatgttcaat
     4561 aaaataactt agtgcgtttt atgttgttat ataaatatgg tttcttatta aataagatga
     4621 aatattcttt aatatagatt tgaattaaag tggaaaggag gagattgtta ttataaacta
     4681 caagtggata ttgtgtccta tttgtggaaa taaaacaaga ctacgaatac gagtggatac
     4741 tatacttaaa aatttccctt tatactgccc caaatgtaag aacgaaactt taattaatgt
     4801 tcaaaaaatg aatataataa caatcaaaga gccagacgcc aagacgcaga gccgataatt
     4861 tgagaaatga aactctcatc ttatcggctc tttttgttta tctgaatttt actgactagc
     4921 cttcaatatt tcttgcttca ttgatacctt ttgctagtgc ttccattaag gatagttctt
     4981 tgtctgtaaa gctatccatg tatttttcta cctgtaacct tcgagtgctt ttaatcaaat
     5041 tatctgtagg taagaaaaat tcatcaatag atacatggag taatgataca agatcataca
     5101 gcacttgtgt acttgggtgt tgtcctttgt tttctatatt tgttaaataa cgtgggtcaa
     5161 tttcaatcat tgttcccact tgttcacgag tgagaccccg tttcattcga gcctctttaa
     5221 tcgctaaacc aacggctcta aaatcgtatt tatcttcttt tttacgcata ctaaatcacc
     5281 tctatacatt ttactgttcc tatataacca taaacaggta tagaaaaaca tgttatatag
     5341 tttatgagtt cctatagaac actgtggaat ttattaatgc gatgaatcca atttcaaata
     5401 gaaaggtcgc tgattttatt tacctataca actttataaa atttagtcat actcctagaa
     5461 agtagataaa attggcgact taatggaggg aaaagtcgcc atgagaaaga taatctgtca
     5521 tctagttctc ttaattaagt tcttatcaaa aaaacttatc cacctgtact ggatagatat
     5581 gaccatcaat gtggttttgc agattacata gatagaaaaa tcaaagcata tgaacagaga
     5641 aaacaatctg tttatgtgct tttttggtca cttaataaat atcttttagg atttctcttc
     5701 atttatgcaa caaatccccc gttcgtgtcg gggtttagta tgaagggaga taaagaagca
     5761 catgccactc cctttcacga cagaaagggg gtgaaaagca tgaaaccatc ttcttttcaa
     5821 gaaaccatag aaaatcagtt tgactatatc tgcaaacaag ttattgaaga tgaacgaaaa
     5881 gattacttca aacatctaga cagactatca gcaaaagaag tctcgttttc tgatatagat
     5941 aactaccttg tcaactcttt ttctactgtt gatacgtacg tcactgattt ccaactattt
     6001 aaattatttg gattaagaat caatgttgaa agtgatttat taagtgaagc cctgcgtcat
     6061 ctttcagaga aaaaacggaa cattatttta cttcattact ttatggatat gagtgatgtg
     6121 gagattgcgg agttactaaa tttgaatcgt tcgactgttt atcgtcatcg aataagtgga
     6181 ctagccatga ttaaagaatt catgaaggag tgtaaagaat gaaaacagct tatccaaggg
     6241 ttcccttccc cctcattgta aaggcgacag atggcgacgt ggaagcaatt aatcagattg
     6301 ttaaacatta tcgagggtat acctcaaaac gttcattacg tcgcatgaca gacgaatatg
     6361 gaaattctca tatggttatt gatgaaaccc tacgtggcag aatggaaacg aaactcatct
     6421 ctaagatttt atcgttcgaa attaaatagt cccatttttt cgtggaagcg tgtcgaatcg
     6481 tatccacgct tcccgatttg ggaggtttgt tattccatca aagcatattg tgtgttcagt
     6541 aggttttgat aggctaacaa gccaaacgtt ctttgacaac caaataaagg caatcgaata
     6601 cgtttcggta agaaaagagc tgatgaacta acacgccatg acctacaaaa ttagtgagcg
     6661 attcatgtta gtaattcgaa agtaatcttt agcaggattg ctgccatgac tttcttatcg
     6721 tgataatgat actcccgtat agccatagtc cgagcgttag aagcgtcaca ggcaatgggt
     6781 acggctacat gagaaccatg cagaagtgaa attcctgtga gctttgctag agctgttcga
     6841 ttgctaagat attcttctct tgtcagtgta ttattataaa actatttgat ataattatag
     6901 gtgaatattg gagttttcct agcctataat tgggaaagga gtaataatga taacggtcac
     6961 aaaaaaggat ttagttgagc taggatatgg aacttctttt tcagcagaca tcataaaaaa
     7021 agcaaaagaa ttgatgatta caaaagggca tatctactat caatctcgaa agctagatag
     7081 agtccctcgt gaagctgttg aagaaattct aggaattcgg ttttcaaatg aaaacaggtc
     7141 tgagtagttt ttgcacagta aggagtaaaa actatggtta aagacccaat aaaaaaagca
     7201 aagaatggaa cctattattt tcgtgcaaat ctaggttatg attctaaagg gaaaaaaatt
     7261 caaaaatatc gtagtggatt cactactaaa aaagaagcaa gagaagaata ttcgaaactg
     7321 ctattgatga aaccagaaga attaagtgag aataaggata aaatgacgtt taaacattat
     7381 atctttgaaa ttttccttcc atggtataag acacaggtaa agctcagaac atatgaaaat
     7441 cgcttaccaa ctattaagaa gcatttctct tattttgata aaatggctgt ttccgatatt
     7501 gagcctattg atgtgcaaaa ttggcaacta aaattatcaa agaagtgtaa gtcttcttat
     7561 gtaagagctg ttcaaggact attttcagtt gctatggatc gagcaattgt ccttgggata
     7621 accaccacaa atccatctaa gattattggc aatgtgaaaa agcaaaagtc taaaattgaa
     7681 ttttggacaa aagaagaatt tgaaaaagta atctctctaa tttacaaaga agattactat
     7741 caacactttt tatttatctc tctgtggttt ttatttatga ctggaatgcg aattggtgaa
     7801 gctactgcca ttcaatggga agatattgat tttgactcag gagtactaac catcaacaaa
     7861 acactctatt acaagaatca atcgaattat agatttgttg aaccaaaaac aaaggcgagc
     7921 gttcgtcata ttgtattaga taaatgcaca ttaacttatt tatccgaatg gaaggaagta
     7981 caacaaaatc taattcagac agactttgta atgagctata acggtattcc tacccaaaaa
     8041 catacactat catatgctat tgaacgctat gctaagctgg ctggtatcca tcgaatcaga
     8101 atccatgggt tacggcattc tcatgcttcc ttgttaatca gtatgggaga aaatccactt
     8161 atcattaaag atcgtctagg acacgaagat attgagacga ctttaggaac gtatggacat
     8221 ctttatccta acagtaattt cgaggtagct aacaaattaa atggagccat ttcctttaaa
     8281 gaagcaaaac aaaattatga tacttcacca aagaatcaat ttactgtaga ctacttgcga
     8341 aacaaagaaa tgaaaaaagt gcaataaaag tgcagtaaaa agataagaag agccagaaac
     8401 ccttggtata agaggatttc tagctctcct acaactattc ccactccact gttgctggtg
     8461 gtttagaagt gatgtcatac acgatacggt tgacgtgggc tacttcgttt acgatacgta
     8521 cagagatttt ttgcaagact tcccatggga tacgggcaaa gtcagcggtc attccgtcga
     8581 ttgaagttac agcacggata ccgactgtgt agtcgtaagt acgtccgtca cccataacac
     8641 cgacagagcg gatccctgga agaacagtga aatattgcca gatatcacgg tcaagtccag
     8701 cagctgcgat ttcttcacgc aagatagcat cagattcgcg tacgatttct agcttgtctt
     8761 cagtgatttc gccaagaaca cgaataccaa gaccaggacc agggaatggc tgacgccaaa
     8821 cgattgaatc aggcatgcct aactgagtcc ctaattcacg gacttcgtct ttgaataatg
     8881 tgtttaatgg ttcgatcaat tcaaattgca tatcttctgg cagtccacct acattatggt
     8941 gagatttgat cgtctgtgct gtttctgtac cagattcgat aacgtcagta tacaacgttc
     9001 cttgtgctag gaaagagacg ccttcttcac cagcaagttt tgttgcttcg tcatcaaaaa
     9061 catatacgaa ttcattccca atgattttac gtttttgttc tgggtcagat acacctttca
     9121 acttgtctaa gaagcgatct cttgcatcga ctttgatgat gttcaagccg aattttccgc
     9181 ctagactttc cattacttgt tccgcttcgc ctttgcgtag cagaccgtgg tcaacaaaga
     9241 tagatgtcaa ttggtcaccg atcgcttttt gtaaaagaac cccaacgaca ctagaatcaa
     9301 cgccacctga aagaccaagc aagacttttt tgtcaccaac ttgttcacgg attttttcta
     9361 cttgcatatc gataaagtta tccattgtcc agttaccttc acagtgacaa acatcaaagg
     9421 caaagtggcg cagcaattcg attccgtatt cggaatgacg tacttctgca tggaattgga
     9481 taccataaaa attacgtgtt gtgtcttgga tagaagcaat cggacaatct ttgcttgttc
     9541 cgactgtttc aaagccttca ggaactttag ttaccaagtc accatggctc atccatactg
     9601 tttgttgttt tggtgtttct ttaaacaaga cagcttgatc gcttgttact tctaacaagg
     9661 ctttcccata ttcgcggttt ttagcaggct ctacggaacc gccaagtttg tacgtgatca
     9721 attgcatacc atagcaaatc cctaatacag gaatacctaa attgaagatc tcaggatcga
     9781 tcccaaatgc attctcatca tatacactgt ttggtccgcc agaaagaatg attccctttg
     9841 gattcatcgc ttttacttct tctgcagtaa tgcggtggct caataattcg gaaaagactc
     9901 caagatcacg aatacgtctt gtgatcaatt ggttatactg actaccgtag tctaatacga
     9961 taatcttttc aacgttcgtc atatcggcaa cgtttgtcaa atttattacc cctatccctt
    10021 taaattttat ctcaaaatag tcaaactatt ttaaaatgct aatattttcg catgaaaatc
    10081 gaatcgatga tatgattttc agttttatgg agaattatat cggctcttcc tcgtgtaggc
    10141 aagatatatt cctgtaaatt tttcaaattc acatttttcc atacatcttt tgccatttta
    10201 aaggcttctt cacgatctcc gatagcaaaa cgataataat aattctctgg attttggaaa
    10261 gccgtatcca gtaacgcacc aaaacgatcc aaataccatt tttcgatcag cacgggatcg
    10321 gcatcgacat agacagaaaa atcaaaaaag tcgctgacgt agatttgctg attcgcaggt
    10381 aattgaagcg tattgatccc ctcaacgatc aagatatcag gctgctggat caattcgtac
    10441 ttgtctggaa tgatatcata cacatcatgt gagtaaacag gtacttttat ctcttcctga
    10501 ccagatttta cacggttcaa gaaatcgatc agcatctcca tatcataact ttcaggaaat
    10561 cctttacggt ccatgattcc acgctctttt aatatacgat ttggataaag aaatccgtca
    10621 gtcgtgatca gctgaacgtt tcttcgtttg aaggtacgag acaaaatcgt ctgcagcagt
    10681 ctggctgttg tactttttcc aacggctaca cttccggcga tcccgataat aaaaggcggt
    10741 acttctacgt atttatgaag aaataaacct ttactcaaga acaaagattc aaattctttc
    10801 atataaagat aaatcagatg agcaagaggt acatagatat ctcgaacatc ctgcatggaa
    10861 atgcggtcat tcaaactttt gatattatct agttcatctt gtgtcaaagg tgcttgccca
    10921 ttacgataaa attctcgcca ttcttctctt gccacacggt agtagttcat tggatcattc
    10981 atattagcct cctgcgttct cccatcaatg gaactatttt aacacaaaat aaacgcaaac
    11041 cccaccactt aagagagatt gccgatcttt ttgtataatc tttataatag aaagaaacgg
    11101 agtcttattc ttgacttgcg cacggataca taaaaggata gactgttgtc atgaaagaaa
    11161 tgagaaggat ggaagacatg acaaatcatt actattctga acgcccagat acggcgcacg
    11221 attttgaaca atgggctttt gagttaaaag gcagaacctt tcaatttgta acagattctg
    11281 gtgtattttc acgtgaaaca gtggattatg gttcacgtgt cctgattgat gctttcgatt
    11341 gggaagagtt acctgatgaa ggaaagatct tagatgtggg atgcgggtat ggaccgattg
    11401 ggttagcttt ggcatttgcg acacagcggt ttgttgaaat ggtcgacatt aatgaacgag
    11461 cggtaagtct agcgcaagga aacgcaaagc gtaaccaaat cgaacatgtt gatatccatc
    11521 aatcgaatat ctatgaagca gttcatgaag aaacctatgc agctatcgta agcaatccgc
    11581 cgatccgtgc tggaaaaaaa gttgtacatg aaattttgac aggcgcatat cctcggttga
    11641 agaagggcgg tacactgaca attgtgatcc agaagaaaca aggagcgccg agtgcgcaaa
    11701 agaaaatgga agaaacattt ggtaatgcag aaatcgtcac aaaagataaa ggatattata
    11761 tcatcaaaag tgtgaaagaa taactagctg aaaaatagtg gagcgacgaa agagtggaac
    11821 tgggcgtgca tgtacgggta cgtatcagtt ctttttttgt tgagaagttt ttaaaaacaa
    11881 agaactattt tttcttcaaa aagaaatagt aggaacagag tcgttgtttt ttacgataaa
    11941 ataaataaga tacagaactt gtatagaagg ctgccaagtc ggtagataaa ggaggttttt
    12001 atcaaaaaac atactttcct tttttctcta ttcttttctt gggggttttg gtacactgat
    12061 agggaattta gatagaaggg agccaatagg atgaagctga ccatcagaga tatcgcagaa
    12121 atggcaggcg tatcagtaac aactgtctca cagattttga ataacaaagg aagcagattt
    12181 agtgataaga caagaaaaaa agtgttgtcg atcgtgaatg aacatcatta taagcccgat
    12241 tatttcgctt caaatgtgat caatcgacat tcaaagacca tcggaatgat cgtccctgat
    12301 gtcactgatt tcttcttctc caaactgatc gaaggtgtag agagctattt gaatcctttg
    12361 ggctatgtga tcatgttatg caattctcgt catagccaag aaaatgagat caagtattta
    12421 caagagcttt cccaccgctc agtggacgga atcttgctgg ccacaccaaa tattttacct
    12481 gagaaatatg cattagacag cggtttttat caaaaaatgc caatcatttt aatcgatcgc
    12541 ggattgaatc gtcgggataa cggacggctt atcgtaaagg aatatgaggg cgcctatcaa
    12601 gctgtttcgc tgtttattga aaatggccat acgaagatcg gcatgctgaa ggaaaccact
    12661 ggatactatc aattagaaga acgtttcaac ggatatcgtc atgcgctgaa agatcatggc
    12721 ctgcctttta atgggaaatt tgttgaacat ggagagttga ctgtccaagg tggatatact
    12781 gcatcaaaaa aattactcaa acataaagat atcacggcta ttttttgcgg gaatgatgcc
    12841 atggcgatcg gatgctatca ggcgatcgat gaattgggca aaaaaatccc agaagatatc
    12901 tcagtcatag gattcgatgg attaaagctg tcagaataca tgattccgca attgacgaca
    12961 gtgcagcagc caagttttga tattggattt tatgctgcac gtttcctgat cgatacgatc
    13021 gaatttcctc aaagaaaagt tccgaacaaa gtgttcgaaa caaaattaat tattcgtgag
    13081 agcgtaaaag tattgacaaa gggctaactc ggcggtatat tgcttatgta agcatttaca
    13141 aaggctagtt agtgcttttt ttatttttag taaaccagtt tactaaagtg gtttaccttt
    13201 cctaaaaata atgtataata ccgaatgaag acaaggagga tcaggcaatg cgaatggtgg
    13261 atctgattga aaaaaagagg gatggaaacg agctgtcgaa agaggaaatc gagtacatcg
    13321 tcacgaacta tacgaatgga aagattccag attatcaagt cagtgcatta ttgatggcaa
    13381 ttttttatca agacatgaca aatgaagaaa tcacgaactt aacattggcg attgctaatt
    13441 ctggtgatgt catcgatttg agttctcttg aaggaataaa ggtagataag cattcgacag
    13501 gtggcgttgg tgacacgacc acattgattt tagcccccct agtagctagt gtcggagtga
    13561 cagtggctaa aatgtctgga cgcggtctag gttacacagg tggtacacta gacaagctag
    13621 aagcaattcc cggatttcag atcgagcttt cggatgaaga atttgtacgc attgttaatg
    13681 aaagtaaagt agcggtaatt ggtcaatcag gaaacttggc accggcggac aaaaaattgt
    13741 atgccttgcg tgacgtcaca gcgaccgttg attctcttcc gctgattgcc agttcgatta
    13801 tgagtaaaaa aatcgcggca ggagcagatg caatcgtttt ggatgtgacc actggagacg
    13861 gtgctttcat gaagaacatc gaagatgcaa gacgtctggc aaagaccatg acgagcattg
    13921 ggaaactggc taaccgagaa acagtggcgg ttatctcaga tatgtcagaa cctcttggcg
    13981 aagctatcgg aaatagtcta gaagttgtcg aggcaatcga aacattacaa ggaaatggtc
    14041 cagaagatct agtagaaatg tgctacgcct taggaagcca aatggttgtt cttgctggca
    14101 aagctaagac aaccgatgaa gcaagaacgt tgcttcaaga agctctggaa tcaggtaaag
    14161 cgttagcaaa attcaaagaa atgatccaaa atcaaggggg agacccagcg atcgtggaac
    14221 atccagaacg aattttgact gcacgctaca caatggagct tcctgctaaa caaagcggag
    14281 ttgtgtcaaa aatcgtggca aatgaattag gaattgctgc aatgatgcta ggtgctgggc
    14341 gtaaaaccaa agaagaagat attgatcacg ctgttggatt gaaactgcat aaaaaaattg
    14401 gtgacactgt gacaaaaggt gagtcactat tgacgatcta tagtaacgac gaagaaatca
    14461 cttctgtcat tgaattatta tataaaaata ttgaaattgg tgaatcggca atgaagccaa
    14521 cgttgattca tgacatcatc acagaataaa ggaaaaaagc ggactttacc gttttaaaga
    14581 aaaggggaaa agaaatggaa ctaaaccgaa tgatcgacca tactattttg aaagcagacg
    14641 catctaaaga agctgtgatg caaattatcg aagaagcaaa aaaataccat ttttattctg
    14701 tctgcatcaa tccagcatgg gttgcgctag cgaaagaaca attacaaggt gagccagtag
    14761 ccgtatgtac agtaatcggg tttcctctag gagcaaacac acccgagaca aaagcatttg
    14821 aaacaacaga tgccatcaat aacggtgcag atgaagtcga tatggtcatc aatatcggtg
    14881 ctttgaaatc aaaggatgat caacaagtcc aaaaagatat cgaagcagtt gttgaagcag
    14941 caaaagatcg tgcgcttgtc aaagttatta ttgaaacatc gttattagat agagaagaaa
    15001 tcatccgagc ttgcgaaata gcaaaagctg caggcgctga ttttgtcaaa acatcaactg
    15061 gtttctcaac aggcggagca aaggtagagg atgtccgttt gatgcgtgaa actgtaggac
    15121 cagaaatggg tgtcaaagct tccggcggta tccataacga agaagaagca atggcaatga
    15181 tcgaagctgg tgctacaaga atcggaacaa gcgcaggagt agcaatcgta tctggttcaa
    15241 ctggtgaagg ctattaattt tttcaaagga gaagctcatg gcagaactca aacaagaatg
    15301 gatcaacaca gctattgaag cgttagataa agcctatgtt ccttattccc attttccggt
    15361 aggcgcttgt ctcgtaacgg aatcaggcaa gatttatcaa ggcatcaaca ttgagaatgc
    15421 atcatttgga ttaacgaatt gtgccgagcg cacagctttt ttcaaagcag tatctgaagg
    15481 agaaaaaaca tttacgcatc tagtcgtagc ggggcacacc cccgatccta tctctccttg
    15541 tggtgcatgt cgacaagtaa tggcagaatt ctgttcccct gatatgccgg ttacgctagt
    15601 aggagacaat ggtgtgacga aggcaacgac cgttcgtgca ctgctgcctt atgcatttac
    15661 tgaaaaagat ctataactca tgttcattca gtcagctgac tgttgaaaaa taaaacaatt
    15721 attttaggag gctttacaga aatgaaaaaa gcaaaattat ttggtttagg tgctgtcgca
    15781 ctagcagcag ggttattttt aggtgcatgc ggcaacaacg gctctactga ttcatccggt
    15841 ggcaaaagct catcagacac aacaactgca gcattgatca cagacacagg tggtgtagac
    15901 gaccgttcat tcaaccagtc agcttgggaa ggactagaaa aatgggggaa agatcaagga
    15961 ctttcacgag gaaatgatgg cttccaatat ttccaatctt caaatgaatc agattacatc
    16021 ccaaatattg accaagcatt gaatgctgga ttcaaaacga tttttggtat tggttataaa
    16081 ctaaaaccag cgatccaaga acaagcaaca aacaatacag gtacgaactt tgttattatc
    16141 gatgatgtca tcgatggatt agataacgtt gtatctgcaa ctttcaaaga caacgaagct
    16201 tcttatcttg caggtgttgc agcagcttat acgactgaaa caaacgtagt cggctttatc
    16261 ggcggtgtaa aaggtgaagt aatcgatcgt tttgatgctg gattcaaagc cggtgttgat
    16321 gcaggtgcga aagaattagg aaaagaaatc aaagtattga atcaatatgc tggtgacttc
    16381 tctgctccag ataaaggacg ttcaattgct caaggtatgt atgcacaaaa cgcagatatc
    16441 atcttccatg cttcaggcgg tacaggtaac ggtgtattcc aagaagcaaa atcattgaac
    16501 gaatcaggcg acaaaaaagt ttgggttatc ggtgttgacc gcgaccaatc agacgaaggc
    16561 gaatacacat taaacggcga aaagaaaaac ttcacattga catctacact gaaagcagtt
    16621 ggaacagtag tagaagattt ggcacaaaaa tcagcggacg gtaaattccc tggcggcgaa
    16681 cacactgttt atggattgaa agaagacggt gttggtctaa cagaaggaca actttctgac
    16741 gaagcgaaaa aagcagttga tgaagcaaaa gaaaaaatca tttcaggtga cgtaaaagtt
    16801 ccagaaactc ctgaagaaaa ctaaaaccat ttctatagcc ttgttagaca catgtttgac
    16861 aaggctatgg tttgattaga acaagaattg ttcatttatc caagctgcct tgtgacagtt
    16921 tggataaggg aacaactccc tgaagtaatg tttgtttcaa aagaagaacg ctcactaagc
    16981 gtgaatctta gtcaatcgtt gccctagata gaaatcgtta ggatgtgaaa aaaaggtggt
    17041 tcaagaaaat attgtcatag aaatgcagaa tattaccaaa gaatttggaa cattcaaggc
    17101 aaatgacaac atcaatttac aagtaaaggc aggagaaatt catgcgttgc ttggagaaaa
    17161 cggtgctggc aaatctacat tgatgaacgt gctttccgga ttattagagc cgacatcagg
    17221 gaaaattttg atgcgtggga aagaagtaaa gatcacaagt ccgaccaaag ccaaccaatt
    17281 agggattggg atggtccatc agcactttat gcttgttgat gcctttactg taacagaaaa
    17341 catcgtgttg ggaagcgagc ctagtcgcgc agggatgctt gaccataaaa aagcacgaaa
    17401 agagatccaa aaagtttctg aacagtatgg attgtcagtc aacccagatg cttacgttcg
    17461 tgatatttca gttggaatgg aacaacgggt agaaatttta aaaacacttt accgaggagc
    17521 agatgtactg atttttgatg agccgacagc tgtattgacc cctcaagaaa ttgatgaatt
    17581 aatcgtgatc atgaaggaat tagtcaaaga aggcaagtcg atcattttga ttacgcataa
    17641 gttagatgaa atcaaagcag tagctgaccg ctgtacagtt atccgccgtg gaaaaggaat
    17701 cggtacagtc aacgttaaag acgtaacctc acaacaatta gccgatatga tggttggaag
    17761 aacggtttca ttcaaaacga tgaaaaaaga agcgaagcct caagaagtcg ttttgtctat
    17821 tgaaaatcta gtggtgaaag aaaatcgtgg attagaagcc gtgaaaaact tgaacttaga
    17881 ggttcgtgct ggcgaagtac ttggtatcgc tggaatcgat ggaaacgggc agtcggagtt
    17941 gatccaagct ttgactggtt tgcgaaaggc agaaagcgga catatcaagc taaaagggga
    18001 agacatcact aataaaaaac cccgaaaaat cactgaacat ggtgtaggac acgtgccaga
    18061 agaccgtcat aaatacgggt tagtcctaga tatgacatta tctgaaaata tcgcactaca
    18121 aacctatcat caaaaacctt acagtaaaaa cggcatgctg aattattcag taatgaatga
    18181 acatgccaga gaattgatcg aagaatatga tgttcgaaca acgaatgaac ttgttcccgc
    18241 aaaagcttta tcaggcggaa atcagcaaaa agcaattatc gctcgtgaag tcgaccgaga
    18301 tcctgatctg ttgattgttg caaatccaac tcgtggactg gatgtaggtg cgatcgaatt
    18361 tattcataaa cgtctgatcg aacaaaggga caaatacaaa gcagtgttac tgatcagttt
    18421 cgaattagaa gaaattttaa atgtttcgga tcgtattgct gttatccatg aaggagaaat
    18481 tgtcggtatc gttgatccga aagaaacatc tgaaaatgaa ttaggtctat tgatggcggg
    18541 ctatacctta gaagaagcac gaaaagagtt agaaaagggg gctggcgcac atgaatgatc
    18601 gcagcgaaaa attccgtaat ttattagtgc ctgtactttc agttgtttta ggattgatct
    18661 taggcgcgat attgatggct gcttttggtt ttcagcccat ccaaggttat tcttctatgc
    18721 tagatgcagc ccttggttcg caaagaggga taggtgaaac gttaaggcaa gcaacgccgt
    18781 tgatttttac agcattaggt ttttctgtag ctaactcagc tgggtttttc aatattgggc
    18841 tttctggaca agcactttgc gggtggatcg tcagtgtctg ggtggcactt gcgtttccag
    18901 atctgccaaa agttgttttg cttccgttat gcgtgatctt aggtgcctta gctggtgcga
    18961 tggcagcggc tgttccaggt ttacttcgag cattttttgg aacaagtgaa gtgatcgtaa
    19021 caatcatgat gaactatatc ttattatacg taagcacatt tgctttacat gaagtgatgc
    19081 ctgaaagcta tcgctcaagt ttggactctt ccaatatgat cagtcaaaat gcctcactgc
    19141 ggttaccatg gttaacacaa gcttttggcg gctctcgcgt aaactcagga ttatttttag
    19201 caatcatcgc gcttattttc gtttggctgc tgatgaagaa aacgacttta ggatttgaaa
    19261 tccgttctgt tggattgaat ccttttgctt ctgagtatgc aggaatgagt agtaaacgta
    19321 cgatcgtttt gtcgatggtc atttctggcg ctttggcagg gcttggcggt gtggttgaag
    19381 gattaggaac gtatcaaaac ttctttgttc aaacgacttc gctatctatt ggatttgacg
    19441 gaatggctgt ttccttgctt ggttctggat cagcaatcgg tattctttta tcagcgatct
    19501 tgttcagtat tttgaagatc ggtggacttg gcatgcagac aggagcaggt gttccgtttg
    19561 agatcgtcaa tgtatcgatt gctttgatta tcttctttgt cgggatcaac ttcctgattc
    19621 gtttcgtcat ggctaaagtc ttccaaggga aaaaacaaga agagatcgtt gcgacaatag
    19681 aatcgaaacc aacgaatcaa aaccatgaag ggggcgaact ataatgtcga ctatcgaatt
    19741 aattgccttg atccttactt ctacactggt ttattcaaca ccgctaattc taacgtcact
    19801 aggcggaact ttttctgaac gaagcgggat cgtaaacgta gggctagagg gaatcatggt
    19861 catgggtgct tttagttcca tcgttttcaa cttgacgatg agtccatcac ttggttctat
    19921 gacaccatgg atcgctattt tagtgggtgg cgtcgtaggt atcctatttt ctctgattca
    19981 cgcagtagca acagtcagtt tgcgtgctga ccatattatc agcgggacag taattaatct
    20041 gatggcacct gctttaggtg ttttcttgat caaagcatgg tatggtaaag gtcaaactga
    20101 taacatcacg cagaatctgg ggtatttttc tttcccagga ttagcagata ttccggtcat
    20161 tggaccaatt ttctttaaaa atacattctt acctgcttat tgtgctattt tgattgctgt
    20221 cctagcttgg gtgatcatct tcaagacgaa attcggcttg cgcctccgtt cagttggtga
    20281 aaatcctcaa gctgccgaca cattaggtat caatgtatat gctatgcgtt attcaggcgt
    20341 actgatttct ggcttgttag gcggtatggg cggtgctgtt tttgctcagt cgatttccgg
    20401 taacttttca gctggtacga tcgttggaca agggttcatc tccatggctg ctatgatctt
    20461 tggtaagtgg aatcctttag gggcaatggg tgcctcattg ttctttggtt ttgctcaaag
    20521 cttgagtatc attggcgcac aattaccagt tatttcttcg attccgccag tattgctgca
    20581 aattgctcca tatttgctga caatcattgt gctggttgtt ttcttaggga aagcttctgg
    20641 tccaaaagca aacgggaaga actatatcaa atcaaaataa tcttttagcg aataaaaagg
    20701 gtgggttacg ggaagtgttt ttcgtctcgc cctttttgtt ttaaaggcaa taaaaataaa
    20761 aagaaagaag gaataatcat gtttaaacgc gtacatctga tcgtcatgga ttcagtagga
    20821 attggagaag caccagatgc cgataagttc ggtgatgttg gttctgatac attaggacac
    20881 attgcgaaag aagcaggatt gaacgttcca catttagagc agcttggttt aggaacgatc
    20941 cgtcctcttg aaggtgtgga atcagtgaaa gatcatcaag gctatgcgac gaaattagaa
    21001 gaagtttctg tagggaaaga tacgatgaca ggccactggg aaatcatggg attgaatatc
    21061 aaaactccat ttcgtgtgtt tcctaatgga ttccctgatg atctgatcaa acaaatcgaa
    21121 gaattttctg gccgtaaagt cgtatgtaac aaaccttata gcggaacagc tgttattgac
    21181 gattacggtg aacaccaaat gaaaacaggc gatttaattg tatatacttc tgccgatcct
    21241 gtccttcaga tcgcggcaca tgaagaaatc attcctttag aagaattata tcggatttgc
    21301 caattcgttc gtgatataac aaaagatgat ccgtatatga ttggccgaat cattgcacgt
    21361 ccgtacgtgg gtgaaccagg agacttcaca cgaacaagca atcgccatga ttatgcgttg
    21421 aatccattcg gacacacagt ccttgattct ttgaaagaag caggaaagga cgtgattgct
    21481 gttggaaaga tcaacgatat tttcaacgga caaggaatca ctgaatctgt ccgcacgaaa
    21541 agcaatatgg atggcgttga ccagctgctg aaagttatga aaaacgattt ttcaggaatc
    21601 agctttacca atttagtaga ttttgatgca ttatacggtc atcgtcggga tgtagtcggc
    21661 tatgcgcatg cgattgaaga atttgactta cgaattccag aattgcttga agcgatggaa
    21721 gaagacgact tgctaatgat tacagccgat cacggaaacg atccgacgtt tactggtacc
    21781 gatcatacgc gagaatatgt accgttattg gtttacagta aaaaaatgaa agaacaaggg
    21841 gcattgcctc aaggatatta ttcagatatt tcagcaacga ttgctgagaa ctttagtgtt
    21901 tcttcgactg aaaatggcga aagcttcttg aaattattaa aataatcttt ttaaatagga
    21961 gaaagcaaat gaccaagtta agcgagatgt tacaagaaac gacccagttt atccttgata
    22021 aaggagtaaa agaaattgat tttggtttga ttctaggttc aggattaggt gaattagcag
    22081 atgaaatcga agatgctgta atgatttctt atgatgagat cccgttcttt cctgtttcga
    22141 cagtagttgg gcatgcagga aagctagttt atgggtctct ggcaggcaag aaagtgttag
    22201 ccatgcaagg gagattccac tactatgaag gtcattccat gcaaacagtg acctatccag
    22261 tacgtgtgat ggccggacta ggggcccatt cagtcattgt gactaatgca tgtggtggtg
    22321 tcaacgaatc atttgtacca ggagatttga tgctgattac cgatcatatc aattttactg
    22381 gtgaaaatcc tttgatcggt ccgaatgaag atgcaatggg ccctagattt ccagatatga
    22441 gtcaagctta tacgcctgac tatcaagcaa cagcaaaagc agcagcagaa aaactaggtt
    22501 tggatcttaa agaaggcgta tatatgggct attctggacc aacttatgaa acgcctgcgg
    22561 agatccgaat gtctcggaca ataggagccg atgcagtagg gatgtcgact gttccagaag
    22621 tcatcgtagc agctcacagc ggattaaaag tgttaggaat ctcttgtatt accaacttag
    22681 cagcaggtat gcaagcgaat ctgagccatg aagaagttgt agaaacaact cagagagtca
    22741 aacaatcttt taaagcattg gttaaagaaa cattgacatt attgtaatag gaggaacaat
    22801 aaaatgagtg tgcatattga agcgaaagaa ggcgagatcg ccgataagat tttacttccg
    22861 ggagatcctt tgcgagctaa atatattgcg gagacttttt tggaagatcc agtttgttac
    22921 aatcaggtac gcggtatgtt aggctttacc ggcaaatata aaggagaacg tatttctgtt
    22981 caaggaacag gaatgggaat gccatcagcc accatctatg cccatgaatt gatccagtcg
    23041 tatggtgtaa agaaattgat tcgagtaggt acatgcggtg cattgtcaaa agacgtccat
    23101 gttcgtgatt tagtactagc acaaggtgca gcgaccagtt cttcgatgat cgaaaaaaat
    23161 ttccaagcct ttcattttcc tccaatcagt gatttcaatc tattactgaa agcatatgag
    23221 atagctaaag aaaagggcta tacggttcat gtaggaaatg ttctttcgga agattctttc
    23281 tacaaagatg atttgacaga gacgttccaa ttagctgaac ttggcgtttt aggagtggaa
    23341 atggaagcag cggctcttta ttacttaggc gcgaaatacc atgtgcagac attaagtttg
    23401 atgaccgtta gcgaccattt gatcaccggt gaagaaacaa cagctgcaga acgtcaatct
    23461 acgttcaatg aaatgatcga agtaggattg gaaacagcga tagcagaata agaaggaaat
    23521 gaaaaagctg ccctgcatta agtaataaga acatccaagc aaaaatagct cctcatgttt
    23581 ttgacttggc tggacttatt attgcaaatg taagcttttg aacaccgttt accaagaggt
    23641 tgtgaatctg ccgtttaact ctgagtcaca aggaacaatt tcaaaaaaca gcttttcatg
    23701 tttgatgaat attgtgactt gtgaccgaga agttggcagg agaaaaccgt ttatacgaaa
    23761 aaagggactg tgacaaatcg tgtcacagtc ccttttttat agtgtttttt ataggtagta
    23821 ttttttagca actgttaagt catcatttaa ttcataaaca agtggttgac ctgttggaat
    23881 ttcaagatcc atgatgtctt cgtcagagat accttcgata tgtttagcta gggcgcgtaa
    23941 tgagttacca tgtgcagcta ctaaaacagt tttgttgtct agtaatgctg gagcaatttc
    24001 atcttgccag aatggcaaag cgcgttctaa tgtcactttc aagttttctc caccaggaat
    24061 atcgcgtttg tctaacattg cgtaacgacg gtcatttgct gcagaacctt cgtcagtttc
    24121 ttccattaat ggaggaagag tatcgtaaga acgacgccag atgtgcactt gttcgtcgcc
    24181 gtatttttca gctgtttctt ttttgttcaa accttgtaat ttaccatagt gacgttcgtt
    24241 taagcgccat gatttgattt gtggtaccca aagttgatct gaatattcta agatcaagtt
    24301 acatgttttg attgcacgag ttaaaacaga agtgtaagca acatcaaatt cgattccagc
    24361 ttctttgatt ttgcgtccgc cttcttttgc ttcttcgatt ccttctggtg ctagatttac
    24421 atcagcccaa ccagtaaatt ggttcaatgc attccattca ctaagaccgt gacgagaaaa
    24481 aactaatttt ggcatgttta gctctccttt taagataggt ttatatttct gaaattttca
    24541 gttctgtttt attgtacaat tttttggaag agatttccat cgaaaaatta gataagattc
    24601 tatgagaaaa caagtagaga atataaaaaa acgaacagtg cccacgcaac tgttcgtttt
    24661 taggtattag atgcataatt gctcgatttc tttttcaggt aaattgatat atttataaca
    24721 tgttccaact gaaacaccgc attttgaaga aataaattgg atcgtttctt ttttttcata
    24781 atagagacgt cggatttttt tgatcgtttt tgcatcgatt tttggtcttc cgccgatttt
    24841 tcctttttta cgagcttcat ctaatccaac taatgtacgt tctttgatca atgcgcactc
    24901 catgtttgct aggttttcca ttaattggaa atagattttt cccatttcgc gcgtatcgat
    24961 tccttcatca agactaatca agtgcagccc gcgatctttg aataattgcg tgagttctgt
    25021 taattgccgc gtagatttgc ctaatcgatg aagttggcaa atgactagtg catcgccttg
    25081 ttgcatgtca gcgatcactg actccaaatg aacagcagta gaatcatttt gttccacttc
    25141 atatgtctca tggaaaattt cttgacaacc aaagtcagat aattgatcaa cctgagttgt
    25201 taaatcaacg tcatttatgg ttgtgcgtgc ataaccaata attttcatgg tgattccttt
    25261 ctagcagtga ttttctaact ggatataaca gtaaaaatgt agcataaagt acgtcaaaaa
    25321 gatagttttt tcgcaaattt tccgctgtct ttttttattg gatgatcaag cagtttttct
    25381 ttatttacga cggattgcgt caagaatctc aacgcctttt tctgagccga caactacttt
    25441 agaaaccatg tttaggaaaa gcccatgttc tactacccca acaagttcat ctaaataggt
    25501 agctaagctt tctggctgtt cgatgacttc tagatgcaga tcaatgatgt aatgaccacc
    25561 atctgtggtt aagacttctc cgttttcgtc tgtacgcaag acgggttgga atcttttttc
    25621 ttcaaaaata tgaagtagct gttgggagcc ataagggatc acttcaactg ggagtgggaa
    25681 cttcccaagt ttatcgacta atttagaaga atcaacgatc caaatcgttt cttttgagta
    25741 cgtagcgact attttctcga aaagcaaagc agcgccgccg cctttgatcc cttgaaaatc
    25801 agcactgatt tcatcagcac cgtctattgt caaatcgact acggggactt catcaatact
    25861 ctttaacggt attcctaatt tttccgcttg ttcttttgtc gcatttgaag tagtaactcc
    25921 tgtgatacgt aaaccttctt cacgcatacg gcgaccaatc tcttctacca tataataggc
    25981 ggttgaaccg gtcccgagac ctacgatcat cccgtccttt acgaatttcg cggcttcaat
    26041 gccagctaat tgttttaaat tcatctttgc gtccaccttt ttttagtttg agcatcgtgc
    26101 tttcctcact attttagcgt gatttacggt aaaaagatac cattcttttt tattccaata
    26161 aagctttttc aaaaaaaatt gcatctcttg ttgacatgtt ttttcattcg tgatattcta
    26221 acaaaggtgc tttatctaca ggtttctgtg aagaaacgtg ctgactgttt atcaaagcat
    26281 atttgataag gatgcagaca ttgcatttat tttttatcac aaaaaaagaa ccacctggat
    26341 gtgtggaact agacgcaaat cgtgggaagg aggaaacaag gaatgcctac aattaaccaa
    26401 ttagtacgta aacctcgtaa atcaaaggtg gaaaaatcta attcacctgc tttgaacaaa
    26461 ggatataaca gctttaagaa aactcaaact aacgtaaact cacctcaaaa acgtggggta
    26521 gcaactcgtg tgggtacaat gacacctaaa aaaccgaact cagctttacg taaatatgca
    26581 cgtgttcgtt tgtcaaactt aattgaagtt actgcttata tcccagggat tggtcataac
    26641 ttacaagaac acagtgttgt attattacgc ggtggtcgtg taaaagactt accaggggta
    26701 cgttaccata tcgttcgcgg tgctttagat actgctggtg ttaacgaccg taaacaaagc
    26761 cgttctaaat acggaactaa aaaacctaaa gcttaatttt aattattaaa caaatgaaac
    26821 ttgcttctac tatatagaag taattactat gaacaatatt tcggaaggag gagttacgga
    26881 tgccacgtaa aggtcctgtt gcaaaacgtg atgttttacc agatcctatt tataactcaa
    26941 aattagtaac tcgcttgatc aaccgtgtaa tggttgacgg aaaacgcggg attgcagcta
    27001 acattatcta taatgccttt gacttgatca aagaatctac aggtaacgat ccattagaag
    27061 tgtttgaaca agcaatgaaa aacgttcaac ctgttcttga agttaaagca cgtcgtgttg
    27121 ggggttcaaa ctaccaagta ccagttgaag ttcgccctga acgccgcgtt actctaggtc
    27181 ttcgttgggt agtaaactac gctcgcttgc gcggtgaaca cacaatggaa gaacgcttag
    27241 caaaagaaat catggatgct gcaaacaaca caggtgcttc tgttaaaaaa cgtgaagaca
    27301 ctcataaaat ggctgatgcc aaccgtgcgt ttgctcacta tcgctggtaa gattctctct
    27361 gtttggtcgg cttttataag tcgacctcag atagtgtcct tatttttagc aactagatag
    27421 taaagagagg agaaacaagg agaatgacca gagaattttc tttacaaaac actcgtaata
    27481 tcggtatcat ggcccacatc gatgctggta aaacgactgc tactgaacgt atcttgtact
    27541 atactggtaa aatccataaa attggtgaaa ctcatgaagg agcttcacaa atggactgga
    27601 tggaacaaga acaagaacgt ggtattacga tcacttctgc tgctactaca gcacaatgga
    27661 agggtcaccg aatcaacatc atcgacacac caggacacgt agacttcaca gttgaagttg
    27721 aacgttcatt gcgtgtactt gatggtgctg taactgttct tgatgcacaa tcaggtgttg
    27781 aacctcaaac tgaaacagtt tggcgtcaag caacaactta tggtgtacct cgtatcgtat
    27841 ttgcaaacaa aatggacaag atcggtgctg acttcttata ttcagtatca actttacatg
    27901 accgtttgca agcaaacgct cacccaatcc aattaccaat tggtgcggaa gacgacttca
    27961 caggaattat cgaccttgta acaatgaagg ctgaaatgta tacaaacgat cttggaacag
    28021 agatcgaaga aacagaaatt cctgaagaat accgcgaatt agctgaagaa tggcgcgaaa
    28081 aattggttga agctgtagct gaaactgatg aagaacttac tttgaaatac ttagaaggtg
    28141 aagaaatcac tgaagctgag ttaaaagaag gtatccgccg cgcaacagtt aacgtagaat
    28201 tctacccagt actatgtggt tcagcattta agaacaaagg ggttcaatta ctattggacg
    28261 ctgttcttga ttacttgcca tcaccgttag atatcccagc tatcaaaggg attgacccta
    28321 aaactgatga agaagtagaa cgtcctgcag acgacagcgc tcctttctca gctttagcat
    28381 ttaaagttat gactgaccca ttcgtaggtc gtttaacttt cttccgtgtg tactctggtg
    28441 ttttacaatc aggttcatac gtacaaaacg caacaaaagg caaacgtgaa cgtgttggtc
    28501 gtatcctaca gatgcatgcc aactctcgtt cagaaatctc tgaagtttac gctggagata
    28561 tcgctgctgc tgttggtttg aaagacacaa ctactgggga cacactatgt gatgaaaaga
    28621 gtctagttat tcttgaatcc atggaattcc cagaaccagt tatccaagtc gctattgaac
    28681 ctaaatcaaa agctgaccaa gataaaatgg gtgtggcttt acaaaaacta tctgaagaag
    28741 atcctacttt ccgtgctgaa acaaacgtgg aaacaggcga aacaatcatc gctggtatgg
    28801 gtgaacttca cttagatatc atcgttgacc gtatgcgtcg tgaattcaaa gttgaagcta
    28861 acgtaggtgc gcctcaagta tcttaccgtg aaactttccg tgctggcact caagccgaag
    28921 gtaagtttgt acgtcagtct ggtggtaaag gtcaatacgg tcacgtatgg attgaattta
    28981 caccaaatga agaaggtgct ggtttcgaat ttgaaaatgc gatcgtcggt ggggttgttc
    29041 ctcgtgaata cattccagct gttgaaactg gtttgaaaga tgctatggaa aatggtgtct
    29101 tagctggcta tccattagta gatatcaaag ctaaacttta cgatggttca taccatgatg
    29161 tcgattcaaa tgaaactgcc ttccgtgttg ctgcttctat ggcattacgt gcagcagcta
    29221 agaaagctaa tccagtaatc cttgaaccaa tcatggctgt agaagttgtt atccctgaag
    29281 attatttagg tgatgttatg ggtcacgtaa ctgctcgtcg tggacgtgtt gaaggtatgg
    29341 aagctcgcgc tggcggccaa caagttgttc gtgcgatggt tccacttgct gaaatgtttg
    29401 gttatgctac aactcttcgt tctgctactc aaggtcgtgg tacatttaca atgacatttg
    29461 accactacga agatgtacca aaatcagtac aagaagaaat cattaagaaa aacggcggaa
    29521 aagctgaata atttcttaaa accggatagt cctgcaaaga gattatccaa agagactata
    29581 tttttaatat agtttcgtgt aaaataatta tcgatgatat gggcatgtgg tgtaccttgt
    29641 gtacatcata tacctatcag acaaataaaa aatatattgt atttttagga ggacatttta
    29701 aaatggcaaa agaaaaattt gaccgttcta aaccacacgt taacattggt actatcggac
    29761 acgttgacca tggtaaaact acattaacag ctgcaatcac aactgtacta tctaagaaaa
    29821 acggcggcca agctatggct tacgatcaaa tcgatggtgc tccagaagaa cgcgaacgcg
    29881 gaatcacaat ctcaacagct cacgttgagt atgaaacaga tacacgccac tacgctcacg
    29941 ttgactgccc aggacacgcg gattacgtta aaaacatgat cactggtgct gctcaaatgg
    30001 acggagctat cttggtagtt tctgctgctg acggcccaat gcctcaaact cgtgaacaca
    30061 tcctattgtc tcgtcaagtt ggtgttcctt acatcgttgt attcttgaac aaagtagaca
    30121 tggttgatga cgaagaatta ctagaattag ttgaaatgga agttcgtgac ctattaacag
    30181 aatacgaatt ccctggtgac gatgttcctg tagttgctgg atcagctttg aaagctctag
    30241 aaggcgacgc ttcatacgaa gaaaaaattc ttgaattaat ggctgcagtt gacgaataca
    30301 tcccaactcc agaacgtgac aacgacaaac cattcatgat gccagttgaa gacgtgttct
    30361 caattactgg acgtggtact gttgctacag gtcgtgttga acgtggacaa gttcgcgttg
    30421 gtgacgaagt tgaagttgtt ggtattgctg aagaaacttc aaaaacaaca gttactggtg
    30481 ttgaaatgtt ccgtaaattg ttagactacg ctgaagctgg agacaacatt ggtgctttac
    30541 tacgtggtgt tgcacgtgaa gacatccaac gtggacaagt tttagctaaa ccaggtacaa
    30601 tcacacctca tacaaaattc tctgcagaag tatacgtgtt gacaaaagaa gaaggtggac
    30661 gtcatactcc attcttcact aactaccgtc cacaattcta cttccgtaca actgacgtaa
    30721 caggtgttgt tgaattacca gaaggaactg aaatggttat gcctggcgac aacgtaacaa
    30781 tggaagttga attaatccac ccaatcgcta tcgaaaacgg tactaaattc tcaatccgtg
    30841 aaggcggacg tacagttggt gccggtgtcg ttacagaaat caaagcttaa ttcacttaag
    30901 ttttaaagta aagcaacatt tattcggacg taatcgctcg gaacgaaggt cttaggatct
    30961 ttgttccgag cttttttatt tattgcagga tcaggaaaaa agacaggagt attataaata
    31021 gaagaaacac gaaataaaag agtcagtatt ttctaaatga aactttatga aaacaaaatg
    31081 ttttttacaa gaaaaagcct tgctttgtga gtttatatat attataatga caaaggtgcg
    31141 tttactttag tgaattgcac agacgtaatc agaatgattt cgtcggctaa gaaacgagag
    31201 gttgcgacac gcccggacgc tttgccacga acgagcgtga cggaaatttt cgtggagcta
    31261 tgtctacttt tcaaaatagg cgaaggaggg aacaagatgg caaaacaaaa aattcgtatc
    31321 cgtttaaaag cgtatgaaca ccgtatttta gatcaatcag cggataaaat cgtggaaact
    31381 gcaaaaagaa ctggagctag cgtgtctggt ccaattccat taccaactga acgcagtctt
    31441 tacacaatca tccgtgcgac tcataaatac aaagattcac gcgaacaatt cgaaatgcgt
    31501 acacacaaac gtcttatcga cattgtgaac ccaacaccaa aaactgttga tgctttgatg
    31561 aagctagact taccatctgg tgtaaacatc gaaatcaaat tataaaacta aaacaaaaat
    31621 aatggaggtg tactcatgac caaaggaatc ttagggaaaa aagtgggaat gacacaaatc
    31681 ttcactgaat ctggtgaatt aattccagta actgttgtag aagctactcc aaacgtagta
    31741 ctacaagtga aaacaatgga aacggatggc tacgaagcta ttcaagttgg ttaccaagat
    31801 atgcgtgaag ttttatcaaa caaacctgcg aaaggtcatg ttgcaaaagc aaacacggct
    31861 cctaagcgct tcattcgtga attcaaaaat gttgagctag gagaatatga agtaggaaaa
    31921 gaaattacag tagatgtttt ccaagcagga gacattattg atgtaacagg tactacgaaa
    31981 ggtaaaggat tccaaggggt tatcaaacgc cacggacaaa gccgcggacc aatggctcac
    32041 ggttctcgtt accatcgtcg tcctgggtca atgggtccag ttgcacctaa ccgtgtattt
    32101 aaaaacaaac gtcttgctgg ccgtatgggt ggcaaccgcg taactatcca aaacttggaa
    32161 gttgtacgtg tcgatgcaga aagaaatgtt atcttgatca aaggtaatgt tcctggagct
    32221 aaaaaatctt taattactat caaatcagct gtgaaagcta aataattgta ggaagaaagg
    32281 aggaactaag gaatgccgaa tgtagcatta ttcaaacaag atggaagcca aaacggtgaa
    32341 atcacactta acgaagaaat cttcggaatt gaacctaatg aaagtgttgt ttacgatgca
    32401 atcgtaatgc aacgtgcgtc attaagacaa ggaacacacg cggttaaaaa ccgtagcgct
    32461 gttcgcggcg gcggacgtaa accatggcgt caaaaaggaa caggtcgtgc acgtcaagga
    32521 tctatccgct caccacaatg gcgtggaggt ggcgtagtct ttggaccaac accacgttct
    32581 tacagctaca aacttcctaa aaaagttcgt cgtttagcaa tgaaatctgt attgtcagaa
    32641 aaagttgctg aaaacaactt ggtagcaatc gaaggcttga acttcgacgc accaaaaaca
    32701 aaagaattca aacaagttct tgctaactta tctatcgact ctaaagtatt ggttgttcta
    32761 gaaaaaggta acgactttgc tgctttatca gcacgtaact taccaaacgt ttctgtagta
    32821 acttctgata atgtgagtgt gctagacgtt gtatcaaata caaaagtgtt agcaacacaa
    32881 actgctctta ctcaaattga ggaggtgctt gcataatgaa cttactagac gtaatcaaac
    32941 gcccagtgat cactgaaaaa tcaatgcttg ccatggatga caagaaatac acttttgaag
    33001 tggacactcg cgcaaacaaa actttagtaa aacaagcggt agaagctgct tttgacgtta
    33061 aagtcaaaaa cgtgaacatc gtgaacgtac gtgcgaaatt caaacgtatg ggcaaatatg
    33121 caggatatac aaaaaaacgt cgcaaagcga tcgttacatt gactgaagat tcaaaagaaa
    33181 tccaattatt cgaagctgct gaataagcac taatagataa ctcattaaat taggagggaa
    33241 aaacgtggcg attaaaaagt acaaacctac ctcaaatggt cgtcgtaaca tgacaggttc
    33301 tgattttgct gaaatcacaa catcaacacc tgaaaaatca ttgttacaac cattgaaaaa
    33361 ccatgctgga cgtaacaaca acggccgcat cactgtacgt catcaaggtg gcggacacaa
    33421 acgccaatat cgcgtgatcg acttcaaacg taacaaagat aacgttgttg caactgttca
    33481 aacgatcgaa tatgatccaa accgttcagc taacatcgcg ttagtacact atgaagatgg
    33541 agtgaaagct tacatcttag cacctaaagg actagaagtg ggtatgaaac ttgtttcagg
    33601 tccagaagca gatatcaaag tcggaaatgc tcttccatta gaaaacattc cagttggtac
    33661 tgttatccac aacattgaaa tgaaacctgg taaaggtgga caattgatcc gttctgctgg
    33721 tacaagtgct caagtacttg gtaaagaagg caaatacgta ttgatccgct tgaactctgg
    33781 tgaagttcgt atgatcttag ctgcatgccg tgctacaatc ggttctgtag gtaacgaaca
    33841 acacgaatta atcaacatcg gtaaagctgg acgctctcgt tggatgcgta aacgcccaac
    33901 tgtacgtggt agcgtaatga accctaatga tcacccacac ggtggtggtg aaggtaaagc
    33961 tcctatcgga cgtaaagcac cagtttctcc ttggggtcaa ccagctcttg gttacaaaac
    34021 tcgtaacaaa aaagctaaat cagacaaact tattgttcgt cgtcgcaaaa ataaataatt
    34081 actttgacca tgtgtcgcac attttgagag gaggttcacc atgggtcgta gtttaaagaa
    34141 aggacctttt gtcgatgagc atttaatgaa aaaagttgaa gctcaagcag gggttgaaaa
    34201 gaaaaaagtt atcaaaactt ggtcacgccg ttcaacagtt ttcccaagtt ttgttggata
    34261 taccatcgca gtttatgatg gacgtaaaca tgtaccagtt tacatccaag aagacatggt
    34321 aggacacaaa ttaggtgaat ttgcacctac aagaacttat cgtggacatg ctgctgacga
    34381 taagaaaacg aaacgctaat ttgaggggag gataaatcca aatggcagaa caaatcacat
    34441 cagctaaagc aactgcaaaa acagttcgca cttcacctcg aaaagcccgt ttagtaattg
    34501 accttatcag aggtaaaagt gtcgcagatg caatttcaat cttgaaattc acaccaaaca
    34561 aatctgctgg aatcattgaa aaagtattga tgtcagcagt tgcgaatgca gaaaataact
    34621 ttgacttaga tgttgaaaac ttggtagtaa gcgaagcttt tgttaacgaa ggacctacaa
    34681 tgaaacgttt ccgtcctcgt gcaaaaggat cagcttctcc aatcaacaaa cgtacaagtc
    34741 atatcacggt agtcgtatca gaaaaataag gagggataat cagtgggtca aaaagtacat
    34801 ccaattggaa tgcgtgtagg catcatccgc gactgggatg ctaaatggta tgctgaaaaa
    34861 gagtatgctg agttcttaca cgaagattta agaatccgta aatttatttc aactaaactt
    34921 gctgatgctg ctgtatcaac agttgaaatc gaacgcgcaa caggtcgcgt aaacatttca
    34981 attcacacag ctaaaccagg tatggttatt ggtaaaggcg gttctgaagt cgaaagccta
    35041 agaaaagaat taaacaaatt aactggtaaa agaatccata tcaatatcgt ggaaatcaaa
    35101 aaaccagatc tagatgcaaa attagtaggt gaaggaatcg cacgtcaatt agaaaaccgt
    35161 gttgctttcc gtcgcgctca aaaacaagcc atccaacgct caatgcgtgc tggcgctcaa
    35221 gggatcaaaa ctcaagtatc tggtcgtcta aacggagcag atatcgctcg ttcagaagga
    35281 tactcagaag gaactgttcc tcttcatact ttacgtgcgg acattgatta cgcatgggaa
    35341 gaagcagata caacatacgg aaaactagga gttaaagtgt ggatctatcg tggagaaatt
    35401 cttccaacta aaaaaaacac tgagaaagga gggaaataat catgttagta cctaaacgtg
    35461 taaaacaccg tcgtgaattc cgcggaaaaa tgcgcgggga agctaaaggc ggaaaagaag
    35521 tagcattcgg tgaatacggt ttgcaagctg ttgattcaca ttggatcaca aaccgccaaa
    35581 tcgaagctgc tcgtatcgca atgactcgtt acatgaaacg tggtgggaaa gtatggatta
    35641 aaattttccc tcacaaatct tatactgcca aagcaattgg ggtacgtatg ggttctggta
    35701 aaggggcacc tgaaggatgg gttgcaccag taaaacgtgg taaaatcatg tttgaaatcg
    35761 caggcgttcc tgaagaagta gctcgtgaag cgttacgtct agcttctcac aaattaccaa
    35821 tgaaaactaa gatcgtaaaa cgtgaggaaa tgggtggtga atcgaatgaa ggttaaagaa
    35881 atcagagaat taaccactgc cgaaatgctt gatcaagaaa aacaattaaa agaagaattg
    35941 tttaatctta gattccaatt agcaacaggt caattagaaa acactgcacg tattaaagaa
    36001 gtacgtaaat cgattgcacg catcaaaact gtgttgcgtg aacaagctaa gtaattatgg
    36061 aaggaggcca ttaagcgtat gactgaagga agaaatcaac gcaaagttta tcaaggtcgc
    36121 gtggtttcag acaaaatgga taaaacaatt accgttgctg tcgaaacaaa gaaaaaccac
    36181 cctatctatg gcaaacgcat gaactattct aagaaataca aagtgcatga tgaaaacaac
    36241 acagcaaaag ttggcgacat cgtgagaatt atggaaactc gtccattatc agctacaaaa
    36301 cgtttccgtt tgttggaagt agtcgaagaa gcagttatta tctaataaca cgagattttc
    36361 ctatatagat tgaatgcaaa atctgaaagg aggatacaca acgtgatcca agcagaaagt
    36421 cgtttaaaag tcgctgataa ctcaggcgca cgtgaaattt tgacgatcaa agtccttggt
    36481 ggatctggtc gtaaaactgc taacatcggt gatgtgatcg ttgctacggt taaacaagca
    36541 acgccaggtg gggttgtcaa aaaaggtgac gtcgttaaag ccgttatcgt tcgaacaaaa
    36601 tcaggagctc gtcgtacaga cggttcatat attaaatttg atgaaaatgc tgcagtgatt
    36661 attcgtgatg ataaaagccc tcgtggaaca cgtatctttg ggccagttgc acgtgaacta
    36721 cgtgaaaaca acttcatgaa gatcgtttca ctagcaccag aagttttata atcttgagac
    36781 acttatcaaa ggaggtgcga aacagttatg tttgttaaaa aaggcgataa agttaaagtt
    36841 atcactggaa aagacaaaaa caaagaaggc gttgtactag cagcgttccc gaaaaaagat
    36901 aaagttattg tcgaaggtgt aaatgtcgtt aaaaaacacc aaaaaccttc tcaagctgct
    36961 cctcaaggtg gaattgttga gatggaagcg ccaattcatg tttctaacgt gatggtggtt
    37021 gactctactg gtgtagctgg ccgagttggc tacaaagaag tagacggcaa aaaagtccgt
    37081 gtttctaaaa aaaccggtga agttttagat aaataaaagt ttaaggaagg agggtcttac
    37141 tgaatgaacc gcctaaaaga aaaatatctt aaagaagtaa ctccatcatt gatggaaaaa
    37201 tttaactata gctctgttat gcaaacacct aaagttgaaa aaatcgtcat caacatgggt
    37261 gttggtgatg cggtatcaaa cgctaaaaac ttagataaag cagttgaaga attaactttg
    37321 atcactggtc aaaaaccaat gattacaaaa gctaaaaaat caatcgctgg attccgttta
    37381 cgtgaaggaa tgccaattgg tgcaaaagtt acattgcgcg gagaaagaat gtacgaattc
    37441 ttagacaaat tggtttctgt ttcactacca cgtgtacgtg acttccatgg tgtaagtaaa
    37501 aaagcctttg acggtcgtgg aaactatact ttaggtatta aagaacaatt gatcttccca
    37561 gaagtagatt atgatttagt agataaagta cgtggtatgg acatcgttat tgtaacaaca
    37621 gcaaactctg atgaagaatc tcgtgagttg ttgacacaat taggcatgcc attccaaaaa
    37681 taattaaagg aggcgaacta cgtggctaaa aaatcaatga ttgctaaaaa caaacgtcct
    37741 gcaaaatttt caacacaagc ttatactcgt tgcgaacgtt gcggacgtcc acattcagtt
    37801 tatcgtaagt tccatctttg ccgtatttgc ttccgcgaac ttgcctataa aggtcaaatt
    37861 cccggcgtga agaaagctag ctggtaaaaa gtaaattcgc ataagaagga ggtaaaagat
    37921 caatggtcat gacagatcca attgcagatt ttctaactcg tatccgtaac gcaaacatgg
    37981 ttaaacatga gtctttagaa gtacctgcat caaaaattaa acgtgacatc gctgaaatct
    38041 tgaaacgtga aggtttcgtt cgtgatgttg aatacatcga agatgacaaa caaggcgtga
    38101 tccgtgtttt cctaaaattt ggtaaaaacg gcgaacgtgt tatcacaaac ttaaaacgta
    38161 tctctaaacc aggtttgcgt gcttatgtca aagctgacga agtaccaaaa gtattgaacg
    38221 gtttaggtat cgcaatcatt tcgacttctg aaggtgttgt cactgataaa gaagctcgtg
    38281 aaaaaaatat cggcggcgaa gttatcgctt acgtatggta atcaagtaga atctacaagg
    38341 aggtgtcttt aagtgagccg tatcggaaat aaagtcgttg ttatccctga aggagtaaca
    38401 gttactcaag acggaaacaa cgttacagtt aaaggaccaa aaggtgaatt gactcgtact
    38461 ttttcagcag atatcaaaat gaatatcgaa ggaaacgaag taactttcac tcgtccaaac
    38521 gacagtaaag aaatgaaaac aattcatgga acaactcgtg cgaacttcaa caacatggtt
    38581 gtaggtgtca gcgaaggttt ccaaaaagcg ttagaactaa tcggggttgg gtaccgtgca
    38641 caattacaag gatcaaaact tgtattgaac gttggttact cacatccagt agaaatcaca
    38701 ccaccagctg gagtaactgt tgaagtacca gctaacacac aagtaattgt taaaggtgcg
    38761 aacaaagaag aagttggcga attagctgca aacattcgtg gaactcgtcc tccagaacct
    38821 tataaaggta aaggtattcg ttatgttggc gaatatgtac gccgtaaaga aggtaaaact
    38881 ggtaaataat cgtttagaaa aattgcatag aagccagcag caggaaaaag gcatttggct
    38941 gaagtttacc ttcaaaaaaa tacattttta cttgtgccgc agcttctatt tttcgaaacg
    39001 tatttactgc ttgaaatagt agtacaataa aaataaagag gtgacaattg tgattacaaa
    39061 accagataag aacaaaacac gtcaaaagag acatcgtcgt gtacgtaaca atatctctgg
    39121 tactgctgag cgcccacgct tgaacgtttt tcgttctaac aaaaacatct acgctcaaat
    39181 tattgatgac gtagcgggtg taacgctagc aagtgcctct accttggata aagaaatttc
    39241 aggtggaaca aaaacagaag cagcacaagc tgtcggtaaa ctagttgctg aacgtgcagc
    39301 tgaaaaaggc attaaagtag tagtctttga ccgtggtgga tacctttacc atggccgtgt
    39361 gcaagcttta gctgaagctg ctcgcgaaaa tggactagaa ttttagaaga aggaggaata
    39421 ccattcatgg tttatatcga tccaaaacat ttggaattag aagaccgcgt tgttgcaatt
    39481 aaccgtgtaa caaaagttgt taaaggtgga cgtcgtctac gttttgctgc tttagttgtt
    39541 gtcggtgaca aaaacggaca cgtagggttt ggtacaggta aagctcaaga agttcctgaa
    39601 gcaatccgta aagcaattga agatgcgaag aaaaacttag ttgaagtacc tatggttggt
    39661 tcaacaatcc cacacgaagt aatcggtgct tttagtggtg gtagaatcct aatgaaacct
    39721 gctgtagaag gttctggggt tgctgctggt ggaccagttc gtgccgtatt agaattagct
    39781 ggggtagcag atatcacttc taaatcttta ggctcaaata caccaatcaa cgttgttcgc
    39841 gcaacagttg aaggtttgaa acaattgaaa cgtgcagaag aagttgcaga acttcgcggc
    39901 aaatcagttg aagaattaat cggataagga ggacaacaat aatggctgaa ttaaaagtta
    39961 ctttaaaacg cagtattatc ggacgtcctc aaaaccaacg cgatacagtt aaagcgttag
    40021 gtcttacaaa gattaacagt tcagtggtta agccttctaa tgaagcaatt aaaggcatga
    40081 tcaatactgt ttctcaccta gtggacgttg aagaaattta atttagaaaa atcataacta
    40141 gaacattaag gaggtgccaa acctatgaaa cttcatgaat taaaacctgc tgaaggttca
    40201 cgccaagtac gtaaccgtgt tggtcgtggt acttcatctg gtaacggaaa aactgccgga
    40261 cgcggacaaa aaggacaaaa agctcgttca ggcggcggtg tgcgtttagg atttgaaggg
    40321 ggacaaacac cattgttccg tcgtttacca aaacgaggat tcacaaacgt gaaccgtaaa
    40381 gactatgcag tcattaatct tgatgtattg aaccgctttg aagacggagc tgaagtaact
    40441 cctgttgctt tagttgaagc tggaatcgtg aaaaacgaaa aagctggaat caaagtatta
    40501 gctaatgggg aactaaacaa gaaattaact gtgaaagcag caaaattctc taaagcagct
    40561 caagaagcaa ttgaagcggc tggtggatca atcgaggtga tctaatgttt agactattaa
    40621 aagatgcttt taaagtaaaa gacattagat cgaaaatcct atttactgta tttgtgttgt
    40681 ttgtatttcg cctaggtgca catattactg taccaggcgt aaatgctgct tcattgcaaa
    40741 acctttcttc tttgccattt ttcaacatgt tgaacttggt aagtggtagt gcgatgcaaa
    40801 acttttccat tttctcaatg ggggtttcac catacattac tgcttctatc gtcattcagc
    40861 ttcttcaaat ggacatcgtg cctcgatttg ttgaatggtc gaaacaaggg gaagttggtc
    40921 gtaaaaaact gaatcaagcg actcgatatc tgacattagt attggcattt atccaatctg
    40981 tcggtatcac tgctggattc aatcaatacg ctcaattagg tttcgtgaat aatcctaacg
    41041 tagcaactta cgtaacgatc ggtttgattc taacagccgg tacgatgttt gttacttggc
    41101 taggagaaca gatcacagaa aaaggtatcg gaaatggcgt atcaatgatc atttttgcag
    41161 gtatcatttc tagattgcct gaaagtatca gagaaattta tgaagattac tttataaata
    41221 ttgatccttc agacatatgg aaatctgcta tttttgtggc cattttacta gtagcggtct
    41281 tgttgatcgt gacattcgta acatttttcc aacaagctga acgcaagatc ccgatccaat
    41341 atacgaaacg cgtagctggc gcgcctacaa gcagctatct gccgttgaaa gtaaatgcag
    41401 ctggagttat tccagttatc tttgctagtt cgtttattgc tacgccaaat gctgttttac
    41461 aagcattgag cggtagattc ggttctgaaa actggtacaa agtgatgatg gagatcttta
    41521 actataatac agcacctggt gctacgattt atacgattct gatcgttgcc ttcactttct
    41581 tctacgcctt tgttcaagta aaccctgaga aattagcgga aaacttgcaa aagcaaggaa
    41641 gttatatacc aagcgtacgc cctggtaagg ggactgaaga gtatgtctca agattactga
    41701 tgcgtttaag tacagttggt gcagtcttcc ttggtttagt ggcattgctt ccaatcattg
    41761 ctcaaatggt ttgggatctt ccacaatcaa tcggattagg cggtacaagc ttactgatcg
    41821 ttatcggtgt agctttagaa actgcgaaac agttagaagg cttaatgctg aaacgtaaat
    41881 atgttggatt cattgagtaa gaaagcgtgt tgaggtttcc cctcaacaca cgttctcaca
    41941 catttattag gagggaaaac aatgaacctc attttaatgg ggctgccagg cgcaggtaaa
    42001 ggaacacaag ctgaaaaaat cattgatgct tatggtattc cgcacatctc aacaggagat
    42061 atgttccgcg cagcgatgca aaacgaaaca gctcttggcc tggaagcaaa gtcttatatg
    42121 gataaaggtg cattagttcc tgatgaagta acaaatggaa tcgtgaaaga gcgactagct
    42181 gaaccagata cagagaaagg cttcttatta gatggctttc cacgtacgct agatcaagca
    42241 aaagctctgg acgcaatgct aaaagatttg aataaaaaaa ttgatgctgt catcgatatc
    42301 catgttggtg aagaaatctt ggtcgaacgt ctagccggcc gatttatctg cagcaattgt
    42361 ggagcaactt accataaaat tttcaaccct acaaaagttg aagacacatg tgatcgttgc
    42421 ggtgggcatg aattctatca aagagaagat gataaacctg agacggttaa aaatcgtctg
    42481 gctatcaaca tcaaaaatag tgaaccaatc ttggcttatt ataaagaaca aggtttgcta
    42541 aacactattg atggtgctcg tgaaatcgat gctgtatttg cagatgtaca aaaaatcatt
    42601 gaaaaatagc acgattgccc gtagccgact tgcattatgc agttactctt gtcaagttca
    42661 ataaattatg atagaatatg tcagtccgac ttctagagaa tcctctagat gatccatttt
    42721 gagaattttg aggtgggaac tgcagtttcc gccattttat cgtgtgaaaa tgcgaaacaa
    42781 gtacaaggag gtactgtgcg tggcaaaaga agatatgatt gaagtcgaag gtacagtcgt
    42841 cgaaactttg ccgaatgcaa tgtttaaagt tgaactagaa aacggacacc aagttcttgc
    42901 tactgtttca ggtaaaattc gtatgcatta catccgtatc ttacctggtg acaaagtaac
    42961 ggttgaattg tctccatacg atcttaaccg tggccgtatt acttatcgct ttaaataatt
    43021 gtactccgta aaactacagg aggtattatc atgaaagtaa gaccatcagt aaaaccaatg
    43081 tgcgaacatt gtaaagtaat tcgtcgtaaa ggacgcgtta tggtgatttg cccagcaaat
    43141 ccaaaacata aacaacgtca aggataattg gaggtgctat aaatatggct cgtattgcag
    43201 gagtagatat tcctcgtgat aaacgtgtag tagtttcact tacttatatc tatggtattg
    43261 gtaacactac tgctaaaaag atcttagctg atgctggtgt atctgaagat gttcgcgttc
    43321 gtgaattaac gaatgaacaa acagatgcta tccgtgcaga agtagataaa ttaaaagttg
    43381 aaggggatct tcgtcgtgaa gtgaacttga acatcaaacg tttgatggaa atcggttctt
    43441 accgtggaat ccgtcatcgc cgtggattgc ctgttcgtgg acaaaacacg aaaaacaatg
    43501 cacgtactcg taaaggccca gctcgcgcta tcgctggcaa gaaaaaataa ttcttaagtg
    43561 aaggaggtta aaacttcatg gcagcaaaaa aagtgaatcg taaacgccgt gtgaagaaga
    43621 atatagaagc aggtattgca catatccatt ctacattcaa taacactatc atcatgatca
    43681 ctgatactca cggaaatgca ttagcgtggt catcagctgg ttcattaggt ttcaaaggaa
    43741 gcaaaaaatc aactcctttt gccgctcaaa tggcagcaga aactgctaca aaagcagcaa
    43801 tggaacacgg attaaagact gttgaagtaa cagttaaagg acctggttct ggacgtgaag
    43861 cagcaattcg ttcattacaa gctacaggtt tagaagtgac tgcaattcgt gacgtgactc
    43921 cagttcctca taatggtgcc cgccctccaa aacgccgtcg tgtttaatga gtgccgctca
    43981 ttttgagttt tatcagtaac gtcattgaac aagacacttt tcgttttgaa aggggtaaag
    44041 ataagaatga ttgagttcga aaaaccaaga atcgcaaaaa ttgatgaaga aaaagattat
    44101 ggcaagttca tcgttgaacc tcttgaaaga gggtatggga ctactttagg gaattcccta
    44161 cgtcgtattt tattatcttc tttgccaggt gctgccatca ctaatattca aatcgatggt
    44221 gtactgcatg aattctctac catcaaaggt gttagagaag acgtcactca aatcatcttg
    44281 aacattaaag gcttagcgct gaaaatgtat ggccaagaag aaaaaaccct tgaaatcgat
    44341 attaccggac ctgctacagt aactgctggc gatattatcg ttgatagtga tgtagaaatt
    44401 cttaacaaag atatgtacat ctgtagtgtc tctgaaggag ctacgttcca tgctcgctta
    44461 acagtgaaac ctggacgtgg ttatgttcaa gcagatgaaa ataaaaaaga agatatgcca
    44521 attggcgttc ttccagtcga ttcaatctac acacctgttc gtcgtgtgaa ctatcaagtt
    44581 gagaacacac gtgttggaca ccgtgaagat tttgataaat tgacgatgga gatttggaca
    44641 gatggttcaa ttgaaccgtt ggaagcaatg agtttgtctg cgaaaatcat gactgaacat
    44701 ttggatattt ttgtgaactt aactgatgaa gcaaaaaatg ctgaaatcat ggtcgaaaaa
    44761 gaagaaacac aaaaagaaaa aatgttggaa atgacgatcg aagagttaga cttgtctgtt
    44821 cgctcttaca attgtttgaa acgtgcagga atcaatactg tacaagaact tacaaataaa
    44881 tctgagcctg aaatgatcaa agtccgtaac ttaggacgta aatcattaga agaagttaaa
    44941 gcaaaattgc acgacttagg tttaggttta cgtaaagaag attaaaacct tttacgaagg
    45001 agggaaacca acgtgagtta tcgtaaacta ggacgcacat ctagccaacg taaagcgatg
    45061 ttgcgtgatt taacaactga tttattaatc aacgaacgta ttgtgactac tgaagctcgt
    45121 gcgaaagaag ttcgctcaac tgcagaaaaa atgatcactt taggtaaacg cggagatttg
    45181 catgcacgtc gtcaagctgc ggctttcgta cgtaatgaag ttgccagcgt gcgtgaagaa
    45241 aatgaggaca tcgtcattga atcagcttta caaaaactgt tcaacgatat tgcacctcgt
    45301 tacgcagaac gtcaaggcgg atacacacgc attttgaaga cagaaccaag acgcggtgat
    45361 ggtgcaccaa tggttgtctt agaacttgtc taaaatcaca ctaataacat cactttatag
    45421 atgattcttt tagagtgtta tgatgttgga agatattttt ccgagtctag ctcagcgctg
    45481 ctcctcaagc gaatatcgct tggggagtaa gcactcatca taaagtgttt ttttatacct
    45541 tcaattacct gtcatgacag atatgtttga aggcataaaa aaacatttta agcgagaaat
    45601 aattgaaaat tttgtctttt tttgatagtg ttagtaggaa ctttaggatg aagaaggagt
    45661 aatcatggag ccaattattg aattagaaaa gataaattat aaataccagc cagatgatct
    45721 tcgccccgca ttgaaagatg tctcctttac aattgataaa ggtgagtgga tcgctattat
    45781 tggacacaat ggttcaggaa aatcgacact tgccaaaacg atcaatggat tgcttctgcc
    45841 agaatcaggg atcgtgaaag tgggaaatca aatattggat gaagaaaata tttggacgat
    45901 ccgacagatg gttggaatga tttttcaaaa tccagacaat cagtttgttg gttcgacagt
    45961 agaagatgac gttgcttttg gtcttgaaaa tcaagggatt cccagagaag aaatgctagt
    46021 gcgtgtgaaa gatgcacttg agaaagttag aatggctgag tttgcttcac gcgagcctgc
    46081 tcgtttatca ggagggcaaa aacaacgtgt tgccattgcc ggcgtggttg ccttacgacc
    46141 tgatatcatt attttagatg aagcaaccag tatgctagat ccagaaggtc gtgaagaagt
    46201 gatctctacg atcaagaaga tcaaagaaga aagtcaattg accgttatat ctatcactca
    46261 tgatattgat gaagcagcta atgccaatcg gatactagtg atgagacaag gcgaacttgt
    46321 ccgtgaaggt acaccaaaag aaattttttc tgctggtcct gaactgatcg acttaggtct
    46381 agatctacca tttcctgaaa aactgaagag cgcactgaaa gaacgtgggg ttgatgtgcc
    46441 cagtgaatat atgacagaag aaaggatggt ggattggtta tggacatccg ttttgaacaa
    46501 gtagacttca cttatcagcc gaatacacca tttgaacaaa gagccttatt tgacatcaat
    46561 atgacgatca aagaaaacag ttatactgca ttagtagggc ataccggaag cgggaaatca
    46621 accttacttc agcatttgaa tgcgcttgtt aagccaacaa gcggtacagt ccatattgga
    46681 gaacgagata ttcagccgga tacggataat aagaatttaa agcccatccg aaaaaaagtt
    46741 ggcatcgtct ttcagtttcc agaagcacag ctattcgaag aaacggtagc aaaagacatt
    46801 gctttcggtc ctaaaaactt tggtgtcagc gaagaagaag cactagtcct agcaaaagaa
    46861 acattagaac aagttgggct ggatgaaagc tatttggaac gttcgccatt tgaactttca
    46921 ggagggcaaa tgcgtagagt agcaatcgct ggtgtgcttg ccatgaggcc ggaagtactt
    46981 gtattggatg aaccaacggc aggacttgat ccccagggca gaaaagaaat gatggagatg
    47041 ttttggcgtc ttcataagga acagcagatc actattgtat tagttacgca tttaatggat
    47101 gatgtagcca attttgcaga ttatgtctat gtgttggaaa agggacgaat cgttaatagc
    47161 ggggagccgc aagaggtctt tcaaaacatt gaatggctaa aagaaaaaca actaggcgta
    47221 cctactgcca ccgagtttgc agaagaatta atggctaaag ggatgaactt tgctaccttg
    47281 cctttgacag ctgaagaatt agcagacgct atcgtccatt atgctggagg aaatgcccat
    47341 gatgaataaa ttgatatttg gtcgttatat gcctggagat tccttgatcc atcgattgga
    47401 tccccgagct aaattattag ccagttttta ttttatcgga atcatttttt tagcaaataa
    47461 ttgggaaacg taccttttgt tggcattttt cacattactt tctgtcttct tgtcaaaagt
    47521 agatttgaaa ttttttatcc gaggcattcg cccattgatc tggctaatcc tcttcactgt
    47581 agctttgcag gtcttgttta caagtggcgg agaaacttat tggagttggg gtgttttcca
    47641 tatcactgaa tttggtgtga tgaacggcct ctttattttc tgtcgattcg tgttgatcat
    47701 ttttatgtcg actctactca cgcttactac accgcctttg gaattatcgg atgcgattga
    47761 gtacttgctt cgtccattga aagccgtacg gttcccagtc cacgaaattt cattgatgct
    47821 gtcgattgct cttcgttttg tgcctacatt gatggacgaa acagaaaaga tcatgaacgc
    47881 tcagcgcgct cgcggtgttg attttggtga aggaaaccta gttcagaaaa tgaaagcagt
    47941 cattcctttg ctgattcctt tatttgtcag cagcttcaac cgtgcggaag atcttgcgac
    48001 tgctatggaa gcaagaggct acaaaggtgg ggaaggaaga acgaaatatc gtgtattgca
    48061 ttggcataat agagacacga tggttatcat tgcttttgta ttattaactg tgctactgat
    48121 ctttttaaga ggataaacgt tcagtgggcc gctatctatt cttttcttgc tgatctgttt
    48181 gcaagaaagg atgcaagcag tgtatgacaa gaaatattag ggtctgtggc agactaaggt
    48241 cacaggcctc tttcttttat ctgaaaagaa agaacgaaaa aattttatag aaaaatcatt
    48301 attccagata accttttagg aacaaaggag agaaaaacat ggtacgttac aaagcaatca
    48361 ttgcgtacga cggaacaaat tttaatggat tccaaaaaca gccaaatggg cgtactgttc
    48421 aagaagaagt agaaaaaaca ttacaaaaaa tggcaaatgg aaaagaaatc acggtctttg
    48481 gttcgggaag gacagatgcc ggagtacatg cgatcgggca agtaatccat tttgattatc
    48541 cagaggagcg tccgttagaa cgaatgcgtt tcgcgctaga tacccagtca ccagaggata
    48601 ttgctgtaag acaagtagaa attgtttcag aagacttcca cgcaagatat ttggtcaaag
    48661 aaaagacgta tcaatttcga gtggatatag ggaaaccacg cagtcctttt cgacgccatt
    48721 atgcaagtta ttttccttac ccacttgatt tggaaaaaat tcagcgggcg cttcctgatt
    48781 tattagggac tcacgatttc acctcttttt gtgcatcagg aagctcgata gaggataaaa
    48841 tacgtacgat ctacgaggct aagatggagg taaatgaaac aaaagacgaa ttgttgttta
    48901 catttagggg aaatggcttc ttgtataaga tgatacggat cttagtagga acgcttttga
    48961 aaattggcaa tggccgattg cctgaagata gtatcccaga tattattgcg aaaaaagatc
    49021 gtaatgcagc aggacctaca gcacaccctg aaggacttta tttgtatgaa gtgaaatatg
    49081 aataagaggt tatgatagaa gtggtcagct tcaagaaata agaaggtatt tacgaaaatt
    49141 acttctcaaa attttgcaaa atttcggctt attttcgaag aagctacttc tggaacaccg
    49201 tttaagaaag aggtcgtgag cctgtcattt aactctgagt cacaaagagc aatttcaaaa
    49261 aacagcttct catctttgat gaatatcgtg acttgtggac gaggcgttga taagtgaatc
    49321 atctttttgt tacctatttt ttctgtaacc aaaaaacgat ggaacgttgt tttgattgcc
    49381 cttggtgcgg acagtctgaa caggttccat cgtttcttta ttttctacgt cttcttctgt
    49441 gtgtgtttcg tggttgttct tctattgctg gatcaatcgt gccataaaag gggcgattgc
    49501 ggtcaaggta ccagacataa agaataaaca atgcaataca taggacaaaa aggattgcac
    49561 ctatcgtaaa tccttcaggc aagtaactga aagtgacagt atgtttacct gctggaactt
    49621 ttatcatcaa gaatgcgtct ttgaaattgc tgaccttgac tggtttccca tcaattttag
    49681 ctttccatcc tttgtcataa ggaatagttg tcaccaacat ggaatcttca gcggtattta
    49741 cagtcccaga agcttttctg ccagtggctt ccatttcgac acctttttct ttgatctgat
    49801 tcattgcggc ttgataggct acaacatcta gaccaacgac tttaggctcc atgaaactta
    49861 tttctttcgt cccataaaaa cttgcagtaa atgtcactgt tgtctcttga ggataatagc
    49921 caagatcata gtattgacca gaaatgttga tttgcgtttt tcgcgatgta ccattgacag
    49981 tgatcgtcgc actagaactt tctaattgcg caaaattggt tgggaacaaa cttaagtaag
    50041 cttgtgtatt tgcaggcaca tggacttccc aagtgagctc ttttggctgg ttatctgctg
    50101 tttctgagta agtgacgcca gtcgttgtct ttgtgatcgt cgtattcaac tgattcttca
    50161 aagtaggtgt atagaatgta aaatactgtt catttagacc agacaatgta ttgatcaagt
    50221 ttgtctgact ggtcaaatta tctgtcactg gctgctcaac atcattaacg gacaacggtg
    50281 cagtaaatgc tagtggcaat gcattgacat tctgatacag tgtatagtcg ccgctttgac
    50341 cagcttggcg gaagccatat ttactgaacg tgctttcgtt tttagaaatg ttatatttga
    50401 ttcctgtaaa cccatccatc agcaaagtat tattgttata acggatattc aaatttgtcc
    50461 ctcttgaacg gaaacctaat ttatccaggt aagaggaaga attacgattt cttatagaag
    50521 aaaacaaact gataccactg taaccatagt tgatcgaatc gtttgcagat actggatcca
    50581 gattttccaa gcggtaaaac gagtcggaat ctttttttgt ttcatttaca agagctttca
    50641 agtcaggata aggatcagta tataaactgc gggaagcata attccaatca tcaagaatgc
    50701 catggatcat actgttcgta ttgaccagtg cttcagcaga catgatcaat aataacaata
    50761 tactcagatg attgaatgaa agttttttat gctgataaaa tcccacagca aaagcataaa
    50821 tccctaagaa aaccactgtc aatacaaagg aagtcatcgt cacataggtg tagcttcctt
    50881 caggtttgat gccccatgcc accgcaaaga gagcagctac gaccaaaatg attcctaaca
    50941 acagcccacc atcgtcttgt tctatctttt cccatccttt tcctgcaagc aggagcacta
    51001 agaaagagaa cagataggca taacggaata aaaacatatt cggtgcatgc ataccatgcc
    51061 agaacaaatt caatggaaca agataaaaac ttgcgataag tatggcgaaa agactgccgt
    51121 acaaaaattt atttttcaac ggtactttcc gactggcaaa ataaaacaga cagaggacta
    51181 atggtagcag acctgcgtaa acgaacggaa tcgatccgta ttttgtcgtg tcataaacac
    51241 caatcatatt tttcatgatt agatccagat aagaagtcgc ttctgttttc aacgtagtga
    51301 tctgactcag tgcctcgcca tttgaccgaa gatccagcac tgctggcaat acaatgatca
    51361 ttgaagcgcc gcctgccagt aaagaagtga taccataagg aacaatcgtt tttttatatt
    51421 ctgaccagtt tgtcaataga cgggcgataa aatataagaa agaaaatacg ccaatcataa
    51481 aacccatata aaaactggat aaaaacaaga gtaaataact gataaataaa agtttcggcc
    51541 gtttaagatc cataacacga tgaatcccca aaatcactaa tggaagataa acaaatgcat
    51601 ccagccacat gatgatctcc gaatgtgcag tgataaatga gatcaatgcg taactgacgc
    51661 taagtgcaac atgcccccag cgaggaatct tgaacgtacg tgcaagaaac caaaaagcca
    51721 atccggcaca gccgacctta agcaaagtca gaacatacag tgcatctggc atcatctggt
    51781 ttggaaaaaa gaacaccagt ggcgtgaaga tcccgcctag atagtaagaa attaaagata
    51841 aataattcaa tcctagagaa gcattccatg tataaaaaat actttgcttt ccaagaagaa
    51901 catttcggaa gctggcatga aaattagaaa actgtgaaaa ggcatcactt gccaaaatac
    51961 ttctgctgct tccaggatag attccgatac ttagataaac aagtgctaaa atcaaaaacg
    52021 gaatcaggaa actagctgct gcgtagcgtc cgttttctct aaagaatgac tttaaatttt
    52081 ttttcatatt tattttccac caaatttcta tgaagttgta ttcagtttat catatccttg
    52141 tttttctctg cttaaaaaga gtctagtttt cacaaaaaaa taaaatttag aataaataac
    52201 ttcataattt gttcgtataa caaaaataaa cgcaaaaaaa gggtaggaat caaaagtccc
    52261 acccttaaaa atttttatta aataaaaaac cgttcactat ctgaacggtc caagtatcat
    52321 tcaattaaac gcgttcaact tttcctgatt tcaaagcacg agttgacacc caaacttttt
    52381 taggttttcc gtcgaccata acgcgaactt tttgtaagtt aggtttaaca gtacgttttg
    52441 ttgagttcat agcgtgtgaa cggttgtttc cactttttgt cttgcgacct gtaaagtaac
    52501 aaacttttgc catggtaatt tcctcctttg ccttgatttg gagcaataga ataattcagc
    52561 tcataccaga ctaacatatc atatagaatg ggaatttgca agtacatttt catagataca
    52621 attgacaatt gagaagaata attgtaaatt aaacaaggtt atacctgaaa ttttgcaagg
    52681 tttttgagta ctttgggtaa ctgcctttta tttcaagttg cgctatgata aaatatgata
    52741 gaagaaaaat gggagttttt tacccgttaa ggaggctcat tcatggctgt aaaaattcaa
    52801 acgtcagctg gaaccattga aattaccaat gatgtaattg caacagttgt tggtggcgcc
    52861 gcgacagatg tgttcggtgt tgtaggaatg gccagcaaaa atcaaattaa agataatatt
    52921 actgagattt tgcgtaaaga aaattactca agaggagtag ttgtccgcca agaagataat
    52981 ggtattgctg tagatgttta tacgattatc agctatggta cgaaaatctc tgaagtttcc
    53041 cgcaacgtcc aagaaaaagt gaaatacaat ctagaggcat tattaggcgt aactgccaat
    53101 tcagttaatg tctttgtaca aggtgttcgt gtactgccag actaggcagg agactggctg
    53161 gtaactcagc agtcgatctg aaggaggatt atctaggtga gtgtaacaga aataagtgca
    53221 agccagttcc aggaaatggt ccaggcaggt gcgaatcgtc tgcaagtaaa tgcagaatac
    53281 gtcaattcat taaatgtatt ccctgtgcca gatggcgata cgggaacaaa tatgaatcta
    53341 tctatgacta gtggagctaa ggcagtagta gattcaacct cagaaaaagt aggagaatta
    53401 gcagcaatgc tttcaaaagg attgctgatg ggtgcgcgcg gaaattccgg cgttattttg
    53461 tctcaattgt ttcgtggatt ttctaagcaa attccagatg ttgtctcatt aaatgcttct
    53521 gatcttgctg cagccttcac tcatggagtt gaaactgcgt ataaagcagt aatgaaacca
    53581 gtagaaggaa cgattttgac agtagctaga gaagcagcga aagctggaga aaagaaagca
    53641 aaaagtactg atgatgtcgt tgaagtaatg acagctgttg taaaaggagc aaagcgtgct
    53701 ttagctaaaa ctccagactt gcttccagtc ctaaaagaag tcggtgtcgt agacagtgga
    53761 gggcaaggac tgctgtttgt ttatgagggc tttttaagtg cattgaatgg agaattccaa
    53821 gcggatgaaa catatgaacc ttctccagca gaaatggatg atatggtcaa tgcagaacat
    53881 catcgcagtg tccaaggtca aatggcgaca gaagatatcc attttggtta ctgtacagaa
    53941 atcatggtaa aaatcggaga aggacctaca gtcgatagta cattcgatta cgaagaattc
    54001 cgtaactatt tagatggtat aggagattct ttacttgtgg tcaatgatga cgagatcatc
    54061 aaagtccacg tgcatacaga aaacccagga gaagtcttga attatggaca aaaattcggt
    54121 tcattagtca aaatcaaagt cgacaacatg cgcttgcagc atgagacgat tttggaacac
    54181 gatgaagaag tgaacgagtt tgcgaaaaaa gaaataccac gtatcccgta tggtatcgta
    54241 gcgatcgctg ctggtaaagg cgtccaagag ctgtttgaaa gtttaggcgc taattatgtt
    54301 atcagtggtg gacaaacaat gaatccaagt acggaagaca ttgttaaagc gattcaagaa
    54361 gtaaacgcag ataaagtgat tgtcttgcca aacaataaga acatcttcat ggcagctgat
    54421 caagcagcag aagtagcaga tatcccagta gcagttgttc cttcaagaac gatttcccaa
    54481 ggattgacag ctatgctttc attcaatgat caagcttctt tagaagaaaa caaagaaacg
    54541 atgacagaaa tgttgtctag cgttgtgagc ggtcaagtca ctcacgcgat cagagatacc
    54601 tcaattgacg gtgtagagat caaagaagga gactttttgg gcatgatcga tggaaaaatc
    54661 ctgatctcta acccagatat cacagcaaca gcgttaagta cactagaaca aatgatcaat
    54721 gaggacacag agatcgtaac gatcttggca ggtgatgaag gaacagttga acaagcaaat
    54781 gaatttgctg agaaactaac agaaaaacat cctgatttgg aaatcgagat ccaccaagga
    54841 gatcagcctg tctatcctta tctattttct gctgaataat ttctgtgtca gaatatcttt
    54901 ctaacacagt attcattcat aaaaggcctt cggttagtga tcaggtatga tcgctgacca
    54961 agtccttttt ttgttaaagg agggaggaaa aatttatgcg ttctttagat gatccaatca
    55021 ctatgctggc aggagtcgga gaaaaaagag cagctagtct tgccagcttg ggcatccaaa
    55081 cgattgaaga cttactgact tattatcctt ttcgctacga agatattcag gaaagaaatc
    55141 taaacgagat ccaggatcaa gaaaaggtta ctttgaaagg aatcgtagtc tcgcctcctg
    55201 tgatgaatcg atttggttat aaaaaaagcc gattgcaatt tcgtatgatg caagaacatg
    55261 atgtgttcaa cgtttctttt tttaatcaac cttatctaaa agaaaaagtc attttatcgg
    55321 aggaaatcgc cgtatacggt aaatgggatg caaagcgtaa agccttgaac gggatgaaga
    55381 ttttaggttc tcaaacaatg gatgactttt cgccgatata tcacgtcaac aaatcaattc
    55441 gtcaaacgac attagttgat ctaatcaaaa aagggtttca agaatacggc acattgattg
    55501 aagaaaatct gccaaacaac cttgtggaga aatatcgact gcttgaccga gcttctgctg
    55561 taagaagtat gcattttcca aaagaccacg aagaaaacca tcaagccaaa cgacgtgtcg
    55621 tttttgaaga gttcttttta tttcaaatgc gtcttcaagg attgaaaaaa gcagaaaaag
    55681 cagaaacgaa tggtttggag atcctttatg atgtccaaaa attgaaacaa tttactcaaa
    55741 agctaccttt tgaactgaca aatgcacaaa aacgtgtaac gaatgaaatc tgtcgggatc
    55801 ttcgcagtcc gcagcatatg cagcgacttt tgcagggaga tgtaggtagc ggaaaaacag
    55861 tggttgccgc gattgcgtta tacgctaccg ttacagcagg tttccaaggt gcgttgatgg
    55921 tgcctacaga aatcttggca caacaacata tggaaagctt gcaacagctg tttgatccca
    55981 atgaagtaac catcgcattg attacggggt caacgaaagc aaaagaacga cgtgagctcc
    56041 ttgaaaaact agagcaaggg gaaattaacg tcgtgatcgg cacacatgca ttgatccaag
    56101 atggagtcga atttcagaat ttaggtctag ttattacgga tgagcagcac cgttttggcg
    56161 tgaaccagcg gaaagtactt cgtgaaaaag gctggcgacc agatgtctta tttatgacag
    56221 cgactccgat tcctagaaca ttagctatta cagcatatgg tgagatggat gtatctatca
    56281 ttgatgaact tccagctgga cgtatcccga tcgaaacacg ctgggtaaga acacctcaat
    56341 tggacagtgt actggattgg acgaaaaaag aactggcaag aggacatcaa atgtatgtca
    56401 tctgtccgct gattgaagaa tcagaagcat tagatgtaaa aaatgcagtg gaaatctatg
    56461 aaaaacttcg tgaactattt gcaccaaaat atgaagttgg cttgttacat ggtaaaatga
    56521 agaatcagga aaaagaagta atcatggaag ccttcaaaga caaccagatg cagatattag
    56581 tttcgactac tgtaattgaa gtaggggtaa acgtgccgaa cgcgaccgtc atgctgatca
    56641 tggatgcgga tcgatttgga ttggcacagc tgcaccaact tcgtggacgt gttggacgcg
    56701 gaagtgatgc ttcctactgt atcttagttg ctaatcctaa aaatgaacta ggtgtggaac
    56761 ggatgaaaat catgacagag accaccaatg gttttgtact aagcgaaaaa gatctggaat
    56821 tacgtggtcc tggtgaagta tttggcttcc gtcaatctgg tctgcctcaa tttgcgattg
    56881 ctgacttggt gacggatgga aatgttttgg aggtagccag agaagaggct gcagcccttt
    56941 ggcaaataaa ggattggcag atgcttcctg agtatcagcc tttagcgcaa agcctccaaa
    57001 tagaaaatca ggataatcgt tatttcgatt agcagactgt gctatacttt atactgatga
    57061 cggaaaaagg agtggaaaca atgaaaattg ccgtagatgc aatgggcgga gatcacgcac
    57121 ctcaagcaat tgtagaaggc gtggctttag cgcagcaaga ttttccagaa gtagaattct
    57181 tactttacgg aaaagaagca gaaatcaaga aatacttaac aaatgaaaaa aacatcacga
    57241 ttatccatac agacgaaaaa atcaatagtg atgatgagcc agtaaaagca attcgacgaa
    57301 aaaagactgc atcaatggtc cttgctgcac aagcagtgaa aaacggtgaa gcagatgctg
    57361 tattttcagc agggaataca ggcgcgctac tagcagcagg gttgttcatc gtaggacgta
    57421 tcaaaaatat cgaacgccct ggcttgatgt ctaccttgcc agtagtaggg aaagaaggtg
    57481 ccggtttcga tatgctggat cttggcgcta acgcagaaaa caaaccagaa catttgttgc
    57541 aatacggtat tttaggttct ttttatgcac gtaaagtccg aggtatcgga cgtcctcgtg
    57601 tcgcactctt aaacaacgga acagaagcaa caaaaggtag tgaagtgacg aaaaaagcct
    57661 atgaactcct tcagaatgaa acaagcttga attttattgg aaacgtagaa gctcgtgagc
    57721 tactcaatgg tgtggctgat gtagtggtca cagatggatt tacaggcaac gctgttttga
    57781 aatctattga aggaacagca atgaatatga tgaatctatt aaaatctgct attctaaatg
    57841 aagggatcaa aggaaaaatg ggcgctatgc ttttaaaaga cggcttacgt tctttgaaag
    57901 cagaaatgga ttattccaaa catggcggtg ccgttttgtt tggcttgaaa gcaccagtca
    57961 ttaaaactca tggagcaaca ggccccgatg ctgttcgcta tacgatccgc caaatccaca
    58021 caatgcttga gacagatgta gttggacaat tagtcgaaca atttgaaaaa agcgaagaat
    58081 agtatttgga tatctgaagc gatccgttcc attgaaaaaa aggtggacat tcctgaaaaa
    58141 tgccagtaaa attagccatg gtgtaggtaa ttgacaagtg tatgattctt ggaggtgaaa
    58201 aagttgactc gcgaagaagt atttaacaaa gtagcgaaaa ttatttcaaa tcattttgag
    58261 atagataccg ataaagtgac ggatgaattg aacatcaaag atgatttaaa agctgattca
    58321 attagtatta tggaattcgt tttagagctt gaagatgaat tcggtacgga aatttcagat
    58381 gaagacgctg aacaaattga aacagtcggt ggcgcagtag attatatcag cagccatctt
    58441 aaataatttc aaataaaagc aaagaaggat aaaaagctgc atgcagcttt ttatccttct
    58501 ttttttaatc tttttgacac gtaaaagtca tttttctgat aattctggcg ataaacagaa
    58561 attatgttgc aaagtaaagc ggttttctat ataattatta ataattcatt acacaaagat
    58621 aagaataacc tttgttataa aacgatttat tctgtgtaat gtcctttttt attaagaaaa
    58681 acttccattt aggaagcaga gaggggtatt cgattgtccg ataaccaatt attagaagtt
    58741 cagaacctac atacaggatt ccgactcaaa gatgactatt acgatgcagt agatgacgtt
    58801 tcatttactt tagacaaaaa cgagatttta gcaatcgttg gggaatctgg gtgcgggaaa
    58861 agtaccttgg ctactacgat tatgggatta cttgatccta ataacacaaa aattacaggt
    58921 gagattttat ataacgatct gaatttaatc gacctgaacg aaacgctcta taataaaatc
    58981 cgcggaaatg atatcggaat gattttccaa gatccgttgt ctgcattaaa tcctctcatg
    59041 agaatcgaag accagatcaa agaaggactt tcctatcaca caaagatgaa tgcagaacag
    59101 cgtcaagctc gtgcactaga attgctagaa caagtaggga ttcctaatcc tgcgagagtt
    59161 ggacgccaat atccccatga actatcaggc ggtatgagac aacgtgtcat catcgcaatc
    59221 gcaatcgcct gcaaacctcc aatcgtcatt gcagatgaac cgacgacagc cctagatgta
    59281 accatccaag cacagattct tgatttactg aaagaccttc aggaagaaac aaaaacaggg
    59341 atcatcttga tcactcatga cttaggagtc gtagcagaaa tggctgatcg agtggcagtg
    59401 atgtatggcg gacagttcgt tgaagtagca ggtgtaaaag aactgtttga tcatcctaag
    59461 catccttata cacgctcttt actgaactct ataccacaag aaggaaatca tgatgcagaa
    59521 ctccatgtga tcgaaggtgt cgttccttct ctgaaaaaca tgcctcgtaa aggttgtcgg
    59581 tttgcaccac gtattccatg gataccagca agcgatcatg aagaagagcc tatccttcat
    59641 gaagtcgcac cgaaccactt ggtacgttgc tcctgctata agcatttcca ctttagagac
    59701 gaaaaaggag aggtgtagat gacagaatta atcacaatca aagacctgaa agttcattac
    59761 cctattcgca gtggattctt caatcgagta acggatcatg tatatgctgt agatggtgtg
    59821 gattttatta tcgaaaaagg aaagacatat ggtttagtgg gagagtctgg ctctggaaaa
    59881 tctactacgg gaaaagccgt tgtgggatta gaaaaggtaa cagccggaca aatcatgtat
    59941 gaaggaaaag atgtaacgaa gcgaagcaac cgcaaaaaaa tgggttataa caaggatgtg
    60001 cagatgatct tccaagattc aatgtccagt ttgaatccta aaaagcgagt gttggatatc
    60061 attgctgaac ccatccgaaa ttttgaacgg ttaagcgatc aagaagaaaa gaaaaaggta
    60121 aaaggactgc tagatatcgt tgggatgccg gaagatgcgc tatataaata tcctcatgaa
    60181 ttttcaggcg gacaacgtca acgtctagga gtagcccgtg ctgttgctac caatccaaaa
    60241 ctgatcgtag ccgatgaacc tgtatctgct ctggatctat ctgttcaagc gcaagtattg
    60301 aatttcatga aacgaatcca gcaagaatac ggcctcagct atttattcat ttcacatgat
    60361 ttaggtgtag taaaacacat gtgcgacaat atcgcaatta tgtacaaagg tcgatttgta
    60421 gaaatcggta caagagaaga catttataat gacccgcgac atatctatac gaaacgtctg
    60481 ctttcagcta ttccgcaaat cgatgtagaa aatagggaaa gccacaaaga aaatcgacga
    60541 agagtagaac aagagtatat ccaaaaccaa aaagaatact atgatgcgac tggtcgagtc
    60601 tacgatttgc gtacgatcac aactacacac aaagtggcgt tgaaagatgg aggtgcaagc
    60661 taatgtggaa aacgattctg cgacgtgttt tattgatgat cccgcaagtt attattttaa
    60721 gtgttctgat cttcttatta gcccaagcga tgccggggga tccatttacc ggtttgatca
    60781 atccaaatca ggatccggca gtgatcgaac agatgcgaca agcagctggc ttgaatgacc
    60841 catggtatgt ccagtacttc cgttggatcg gaaatgcttt gcaaggcgat tttggtcaaa
    60901 gtttcttata caaacgctct gttgctgact tgatcggcga acggatcatc aacactttat
    60961 atctatcgat cttgacagtt gtccttactt atttgattgc tgtgcctctg gggatgcttg
    61021 ctggccggta tcaaaattca atcttggata agattgtcgt aatctacaac ttctttagtt
    61081 ttgctgttcc tttatttatc ttcggcttga tcatgctatt tgtttttggt tatcgtttag
    61141 gctggttccc aacaagtgga tcacaaacac taggtttgca aggtggattt atcactcaat
    61201 ggatagaccg tttgaaatat attctgttac catcaattac ccaagcattt ttggcgactg
    61261 ccgtcacaat ccaatatctg cgaagtgaag taatcgattc gaaatcgctc gattttgtca
    61321 gaacagcccg ttccaaaggg gtaccgacga ataaagtatt cagtcgacat attttccgaa
    61381 atgcagcgtt gccgatggct tctcaaatgg ggtatgaaat cacttcgttg attgctggtt
    61441 ctgtagttat cgaaaagatt tttggttatc cgggagtcgg aaaactattt attgattcca
    61501 tcggccaacg ggactatacc gtgatcacat ccttagtatt gattttagga atcgcgacgc
    61561 tagtggggac attactttca gatatcatca tgagtatcgt tgacccgcgt attcggattc
    61621 aataaaacca atcagaaagg agaatggatc gatgagtgaa aaaaacaata cagcagttca
    61681 agaaagtatt cctcctatgg ggatacgaat gattgctcga gaatttaaaa aagataaaat
    61741 tgctattttt tcattaggtt tgctagtggt tttattatta gtgatcttta tcggtgcgat
    61801 gctgaccgat caagacaaag tgatgtatgt tagtatcttc gacaaatacg ctgcaccagg
    61861 aacagtttcg acacaaggac aaaagttcat tctgggagca gatgaaggcg gacgtgatgt
    61921 attaggacaa ttgatcatag gtgctagaaa ctctgttacg atcggatttg cgatcacgat
    61981 ccttacttcg atcatcgggg ttggattagg gatcatctct ggctactacg gagggatcat
    62041 tgacaacatc ttgatgcgga tcgttgattt tatcatgatt ctaccgatca tgctgatcat
    62101 tatcgtcttc gtatcgatta tttccagata caatgtctgg tcctttatat tcatcatgag
    62161 tgcattttat tgggtagcta aagcccgatt attccgaagc aagacattat ctgaagcaag
    62221 aagagattat gtcagtgcct caaaaacaat gggaaccaat gattttaaaa tcatgttccg
    62281 cgaaatcatg ccgaatctaa gttcattaat cattactaat ttgacgatga actttgcggc
    62341 aaacatcggt atcgagacaa ctttgacttt cttaggtttc ggcttgccgg caaatgtacc
    62401 tagtttaggt acattgatcg gttatgcaag taacggagaa gtcttagtga atcggcaatg
    62461 gatctggtta cccgcatcaa tccttatttt agttttgatg ttgagtatca attatgttgg
    62521 acaagcattc aagcgttctg cagatgcgcg ccaacggtta ggctagtata gaagcgaagg
    62581 gggaaatagg aatgaagaaa acgatttttg gatttgcagc gctgatgtct gctgtcgttc
    62641 ttgcagcatg cgggggcgga ggtacagata cctctggaaa caactctgga ggcaacggca
    62701 ataacaaaga ggaattaact tttccaattg caacaaaaaa taatgatgat gcaatcgaag
    62761 acggcgaatt agaagctgcg gtcgcaacgg acagtcagtt taaaggattg ttccagtggg
    62821 agttttacca agattcatat gatgcagctt ttatggctcc ttctcatgaa ccgctatttg
    62881 caaacgatga cgatttcaga atcacagacg acggagctgc aacgcttgat ctagatgaag
    62941 atacgaaaaa agcgacaatc aaagtaaaag acaacgtcaa atggtcagat ggtgaagatg
    63001 taacggcgga cgatgtgatt ttcccttacg aaatcattgg gaataaagat tacactggta
    63061 tccgttatga cgacactttc cgtaacatcg taggtatgga agaatatcat gatggaagtg
    63121 ccgacacaat ctccggaatc aaaaaaatag acgacaaaac agttgaaatc gaatataaag
    63181 aagtaaaccc aagcatgctt caatcgggtg gtggtatctg gtcatatgca gcaccaaaac
    63241 atacgttaga aggtgtagca atcaaagata tggaatcaag cgatcaagta cgtaaaaatc
    63301 cagtgacttt tggcccttat tacatgagta atatcgttgc aggagaatca gtagaatact
    63361 tgccaaacga gcactactgg aatggtacgc ctaaattgaa aaagatcacg atgaaatctg
    63421 taccgatggc aagtgcaact gaagcattga actctaaatt atatgatatg attttccaaa
    63481 tgccaacaga tacttacgat acctataaag aaattgctgg ctatacaaac ttaggccgtg
    63541 aacaaacttc ttatacttat ctaggattca agttaggtaa atggaatgca gatacaaaga
    63601 gtgtggaata caatccagat tcaaaaatgg ctgataaatc attacgtcaa gcaatgggct
    63661 atgcattaga taataatgca gtaggtgaac gtttctatgc aggtttgaga agcaatgcga
    63721 cttcattgat tcctccagta ttccagtcat accatgatga tgagatgaaa ggattcacac
    63781 aagatctaga caaagcgaaa aaactattag atgatgctgg ctacaaagat gtggatgacg
    63841 atggtttaag agaagacaaa gatggaaata aactaacaat caactttgct tcgatgtccg
    63901 gtggggaaac agcgcaacca ttggcagatt actatatcca acaatggaaa gaaattggtt
    63961 tggatgtcca atacacaaca ggtcgtctga tcgaattcaa ttctttctat gataaattag
    64021 aaaacgatga tcctgaaatt gatgtttacc aagctgcttg gaatacagga actgatccaa
    64081 atccaagtgg actatgggga ccaaatgctg cgttcaacta cactcgttat gaatcagaag
    64141 aaaatacaaa attgatcaac gatatcagtt caagcaaagc atttgatgaa gagtaccaaa
    64201 aagaagcata tcaaaaatgg caacaatatg catttgaaga agcatttgcg attccaacgt
    64261 tgttccgtaa tgaagtattg ccagtcaacg accgtgtcaa agactgggat tggtcttatg
    64321 atgtaccaaa cccatgggca aatgtttctg ttacagcaga ttcacgttca taatcactaa
    64381 aaatgaccga aaaagggcga tgtccttttt cggttttttg atatttttct gtttatttct
    64441 ctaatattca ggtcaaggcg ctgatttcat gacttctcca ataaacggtg ttcaaagtcc
    64501 agtttctcgg tattaagtca aatttatgca aaaatatgga aagccatttt cacaaaattt
    64561 tttcttcata ctcgaaacta aacgaatttt tcacaacttc tcgtcaatca ctaggattat
    64621 taaagcttta cttacctttt gaccgaacca tttcaaattt gacaaaaaac cagtataata
    64681 aggaagtatc gaaaaaatat ccataaaagg aatgtggaaa atggacaacc agctgacaaa
    64741 agaactaaaa gaaaactata acatcgtttt tcacgatcta aatttgcttg aacaagcttt
    64801 tacccattca tcctatgtga atgagcatcg caatctgcaa ttatcggata atgagcgact
    64861 tgaattttta ggagatgccg ttttagaact gatggtttct cagtatttat tccgtttata
    64921 tcctcatttg ccagaaggaa aattgacaaa aacacgagct gcgatcgttc gcgaagacag
    64981 cttgtcgaaa tttgccaaag aatgtcactt tgatcaatat gttttgttgg gcaagggaga
    65041 agagaattca ggaggacgta cgcgaccagc attgctttgc gacctattcg aagctttttt
    65101 aggcgcgtta tatcttgacc agggattcga cacgacccat gcattcatcg aaaaagtgat
    65161 ttttcctaaa gtcaaagcag gtgctttttc acatgagatg gatcataaaa caaaactaca
    65221 agaagtcttg caaaaatcag gtgatgtatc aatcgaatac cgattgatca atgaagaagg
    65281 tccagctcat gaacgagtat tttggatcga agtttatgta gatgatcaat tgattggcac
    65341 tggacaaggg aaatcgaaaa aattagcaga acaagctgcg gcggaaaatg cattggcagc
    65401 actgtaaaag taagtgaggg aaagctttgt atttgaaacg aattgaaata gccggtttta
    65461 aatcatttgc agacaagaca gtcattgatt ttgaaaatag cgtcacagca gtggttggac
    65521 caaatggcag cggaaaaagc aatattacag aggctatccg ctgggtatta ggagaacaat
    65581 ctgctaaaag tctgcgaggc ggaaaaatgc cggatatcat ctttgccggt tccgataccc
    65641 gtaagcagct gaatattgca gaagtcacag tgattttaga caatagtgat cattatctgc
    65701 cattggagta caatgagatc agtgtaaccc gccgttatcg acggactggg gaaagcgagt
    65761 ttttcatcaa taaacaaagc tgcagattaa aagatatcca agaattgttc ttagattctg
    65821 gattaggaaa agaatcgttc tcaatcattt ctcaaggaaa agtagaagcg attttcagta
    65881 gtaaaccgga agaccgtcgt gggatctttg aagaagcagc tggtgtcttg aaatacaagc
    65941 agcggaaaaa gaaagcagaa cagaagcttt ttgaaacaga agacaacctc agccgcgtcc
    66001 aagacatcat ccacgaattg gaagaacagt taactccttt ggccgcccag agtgaggcag
    66061 caaaggagtt tttacggcta aaagaaacac tgactcaaac cgatgtctct ttgatggttg
    66121 ctgaaatcaa gacagcaaaa aaagattggg acaacaaaca agcacagctt gcgaaattca
    66181 atctagaatt aggcaaacta tctgagtcga tccaagaaca agaatccatt ttggcgaagc
    66241 agcgtaaaga aaatgcgcaa gccgatcgtc tgatcgaaaa aaatcagcaa gtattattag
    66301 atctttcgga aaaactgaag cagacagaag gacaaaaaga tgttttgcag gagcggacaa
    66361 agcatacaca aaaaagctcg caagaatatc aaacttcatt agcagaagca caaaaaaagg
    66421 ttaaacattt tgaaaagctt caagaaagct tgatgaaagc agcagcagaa aaagaaacag
    66481 agatccaaaa agctgaagca aatctcataa aaacacagca agaattagaa aaataccaaa
    66541 aatcaacgaa agaattattg gcagaattaa gagatcaata tgttgatttg atgcaagaac
    66601 aagcagctgt aggaaacgaa ctgaagtatc tagaacgtca atatatacaa gaaacagcaa
    66661 aaagcaagca gacgttagcc aagcaatcgg aagtagaagc atcagtagac cgattgatct
    66721 tacaaaaaga agaattgaca caaaagcagg cgcagctaaa atcatcttta actgaaacaa
    66781 aagagaagtt agaaatgatc caacaaaacg ggaaaaagtt ccaagaagca ttagcaaaag
    66841 aacagcctaa aatgtatcaa ttaatgaatc aagtccagca gctacgtgct cgtaagaaaa
    66901 gccttcaaga aatccaagaa aactattttg gtttttacca aggggttcga ttggtcttgc
    66961 agcataaaca gcagctttcg ggtattgtcg gagcagtggc tgaactgatc gatgttcctg
    67021 cagatttcac gttagctatc gaaacagctt taggtggggc agcccagcat gtcatcgttg
    67081 aaaatgaaaa agatgctcgg caagccatca cgtatttgaa acagcaaaga ggaggaagag
    67141 caacattcct tccactgacg acaatcaaac caagacaatt accggctcat atattgacac
    67201 aagcagcagc tgtagaaggg tttataggga ttgccagtga acaagtcagt tatcccgatc
    67261 aaatccaaac tgtggttcaa aacctgctag gaacgatcct tttagccaaa gacttaacta
    67321 gtgccaatgc aatcgcgcaa acgatccgct atcaatatcg agtggtttcc ttagaaggtg
    67381 atgtgatgaa tgccggagga tccatgacag gtggagcgaa taaacgagga aaccaaggca
    67441 gtttgtttgt acaaaatcaa gaattgaaac agttgactag tgaatttgaa gaagcagata
    67501 aacaactcca agcacaagaa aaaaaagttc aggagctgca acaagaaaca gctcgtttag
    67561 ccgaagaaca agaagttttg cgtacacgag gcgaacaatt acgttttgaa gaacaagaag
    67621 cgacaaatca gctacaaaac atcataaatg aacttgaacg ttttgaaaaa gaaaagcaaa
    67681 tctcaacttt tgagacacgt gaactgcagc agtttatcga agattacgaa aagcaaacga
    67741 acgaattgaa agacaaacaa acagatcttg aatcgcaacg acaaaaaatc gacgaagaaa
    67801 tcaaatcgtt aagtcaagaa agcgaccaga tggaagccag aagagcacaa gtacaaagtc
    67861 aaaaagcaca agaacaagca gatcttgctg tcttgaaaga gcagtttaat catctgcaga
    67921 tccagctccg cggtgcccga gtccaaaaag cagaggcaac cgaacgtcaa gaagcgatag
    67981 aaaagcagtt ggcgacattg acagcagact tttctgatca tgaagtcaca gaagaaagtt
    68041 tggaaaaaca aattaacgaa ttatctgctc agcgagaaac attaaaagcc gagttggcaa
    68101 aagccaaaga gcagcgagat agaaggcaaa aggagatcga taagcttgaa gcagtcttgg
    68161 cagagcgtaa tcgtgagcaa aaagcacgac tgtcggaaca atccaaatta gaagtccaaa
    68221 aagaccgagc tgaaatgatt ttagataatc atttgaccta tctgcagtca gaatatcagc
    68281 tgacatttga gaaagcttcc caagactatc aagaaacaac cgatatcgaa gacagtagaa
    68341 caaaggtttc atccttaaaa gaacagattg aaaaactggg accagtaaac ttaaattcaa
    68401 tcgaacaata cgaacaagtc agtgaaagac atacattctt agcaacacag cgagatgatc
    68461 tgttagcagc gaaaaaccaa ttgtttgaaa cgatggatga gatggatgat gaagtgcgga
    68521 caagattcaa agaagtattt gaagctatcc gtcaagaatt caaaattgtc tttccaaata
    68581 tgtttggcgg cggtaaagct gaattagtac tgacggaacc aactgatttg ctgaaaacag
    68641 gtattgagat tgaagtacaa cctcctggca aaaaactgca aagtctaagt ttgctttctg
    68701 gaggagaacg agcacttaca gccatcgcgt tgctcttttc cattatccgt gtctgtcctg
    68761 ttccgttttg tatcttagat gaggtagaag cagcgttaga tgaagccaac gtgaaacgtt
    68821 ttggtcgtta cttgagcgat ttccaagatg acacacaatt tatcgtagtc acacaccgca
    68881 aaggaacgat ggtcgcagca gatgtactgt acggagtgac gatgcaggaa tccggtgtat
    68941 caaaaatcgt ttctgtacgg atggaagata tcaatgaaga ggcgaaaatc aacgaaacga
    69001 aagtgtagga acgaaaatga tcaaattagt agcaatcgat ttggacggta cattattaaa
    69061 tgaacaaaag ctgatttcag atgagaataa acaagcatta gcacaagcaa aacagcaagg
    69121 ggtcaagata gttctatgta caggacgccc cttagctgcg atggcgcatt atctgcaaga
    69181 attaggactg gtagatgaag gtgactacag catcactttc aacggcggtt tggtacaaaa
    69241 aaatgatact ggtgaaatca tggaaaagaa agtgatggaa gtatcagata tccaacgctt
    69301 atacaaactg gctcagcaat tggatctgcc actagatgtt ttgtctgaca atgtggtttt
    69361 acagctgcct agtgccccaa ggaagcaatc cttgtacaat gtgttgaata agctgctgca
    69421 attccaacca gcggatataa gcgatattac agatgaattt gtgcttaata aggcagtaat
    69481 cgcttatgac caagaagaat tagatcctaa aatcaaagaa ataccagcag aattccatga
    69541 aatgtatgag atcatcaaaa caagaagtat gcttttggaa tttatgccaa aaggtgttac
    69601 aaaagcttat ggtatttctt tattggcaaa agatcttggt ttgaaacaag aagaaatcat
    69661 ggcgatcggt gatgaggaaa atgatttacc gatgatccaa tatgctggac taggcgtagc
    69721 gatggagaat gctgtgcctt tcgtcaaaga agcagcagat ttcgtgacag ccagcaatga
    69781 agaaaatggc gtagccaaag tgatccaaaa atttgtatta gagtaggggg agtcaaatgg
    69841 gattttttga taaaatcaag cgtgctttta ctggcgaaga gaaaacagaa gaagttgaag
    69901 tacaggagaa gtacgacaag ggtttagaaa agacgcgtaa aacatttggt gaacggatga
    69961 atgagttgtt tgccaatttt cgaacagtcg atgaagactt ttttgaagaa ttagaagaaa
    70021 cacttatcgg tgcagatgta ggttttgaaa cagcgatacg aattaccgaa gcattacgtc
    70081 aagaagtgaa actcagaaat gcgaaaaaat cggcagaagt ccaaaatgcg atcatcgaga
    70141 aacttgtgga tctctatgaa gcggaaggaa tcaatgaagt aaatgaacta aatatccaag
    70201 aagacggact aacagttatt ttgtttgtcg gtgttaatgg tgtagggaaa acaacaagta
    70261 ttggtaaact tgcccatcag ttcaaaaacg aaggtaaaaa agtattgatg gcagcagcag
    70321 ataccttccg cgctggagca atcgaccagt tagttgtctg gggcgaacgc gctggtgttg
    70381 aagttgttcg tggcaatgca ggaggcgatc cagcagctgt cgtattcgat gctttggaaa
    70441 gagcaaagac agagcaggca gatgttttac tagttgatac tgcaggccga ctgcaaaata
    70501 aagtgaactt gatgaacgaa ttagaaaaaa taaaacgagt aatccagcgg gaattaccag
    70561 aagcacccca agaaacactt cttgtattag atgcaaccac tggtcaaaac gcgatggttc
    70621 aagcaaaaca attcaaagaa acaacagatg tgaccggtct tgttttgaca aaattagatg
    70681 gtacagcaaa gggcggtatc gtacttgcta tccgtaatga attgcattta ccagtgaaat
    70741 tggtcggtct tggtgaagga atcgatgact tggagccgtt tgatccaaat gattttgtcg
    70801 ttggattgtt caaaggatta ctaaaagaag aataacccat gtctaaaaag caggagctgt
    70861 gacaaaagtt gcagctcctt gtttgaatga ttgtttttaa catagctgtg tttttgatgc
    70921 cttcattttt atacttattt gtaagcggtt ctcaaacaat ttcgttcttt ttcttagact
    70981 ttttgattat aattagattc atatgaattg gaggtcactt aatgatgaat tttaagcaat
    71041 tattattgca tgtcaatgcg cgccctttta tcgaccaagc tcgatttggt atagaacggg
    71101 aaggacagcg ggttgatctt gcaggaaatc tagcaaaaac cgatcatcca gcaatctttg
    71161 gcgatcgatc ctatcacccc tatatccaaa cagattttag cgaaacacaa acagagatga
    71221 tcacccctgt taccgattct attcccgaat tatttcagta tctcgctgct gtttatgatg
    71281 tgactgctcg ttctataccg aaagaagaga tgatctggcc attaagtatg ccacctgcct
    71341 taccggaaaa agacgaagag atcattattg caaaattaaa aaatttcgaa gatgtcttgt
    71401 atcgacgtta tttagcaaaa gaatacggga agcgaaaaca gatggtaagc ggtattcatt
    71461 tcaattttga atttggcgat gagttgctaa gaacattgtt cagccatcag gaagaatttc
    71521 aagatttttc cgaattcaaa acagaacttt atttgaaaac agcgagaaac tttatgcgct
    71581 atcgctggat gatcacttat ttattcggtg cttcaccaat gagtgagaag aactactttt
    71641 tagatgaatc acatccgcaa gaacctgttc gcagtattcg caacagtgcg ctgggctata
    71701 cgaatcatcc aaatgtgaaa gtttcctatg cttctatgaa acagtattta gcagatatcg
    71761 agcgaatgat cgaagaaggg aaactttcgg aggagaaaga attttataca ccgcttcgtt
    71821 tccgaggcgg aaagaaagtc gcagatttag caacaacagg tgttcgttat attgaattgc
    71881 ggaatatcga tttgaatcct tatgcaagat tgggtatcaa tccagagcaa gttcggttct
    71941 tacaattatt cctgatgtac atgttatgga cagaagaaaa agaagactgt gaccaatggg
    72001 tagcagaagg tacgactcga aataacaaag tagcactaga acaaccatca gatcaaacag
    72061 aatttcatca agaaggtaga gaaattcttg aaggaatgaa gcaaatgctg gttgaattgg
    72121 attggttgga ttctctttat ttagtagagg aagcattgac tcaaatggat catcctgaac
    72181 aaacgttagc agcgaaactc tatcaagaag cacagctatc gagtcagcaa gaagttgctg
    72241 tggcattggg acatcaatat tataaagaaa gccatgaacg tccctatcag ttggccggtt
    72301 ttcgcgaaat ggaactttct actcagatat ttatgttcga tgccatccaa aaaggtgtcc
    72361 aagtcaaagt attagatgag tcggatcaat ttttgcgtct gcaattccaa gaccatgtag
    72421 aatatgtgaa aaatgcaaac atgacaagta aggacagcta tatcgtccca cttatcatgg
    72481 aaaacaaaac agtaacgaaa aaagtcttaa aagaagctgg gttccgggta ccaggaggcg
    72541 cagaattttc atccatggaa gaagcggtaa aagcttatcc gagatttgcc gagcaggcat
    72601 ttgtgatcaa acctaaatca accaattacg ggttaggtat cacgattttc aaggaaggag
    72661 ctagtctgga agattatcaa gcaggtttag ccattgcttt tcgtgaagac agttcggttt
    72721 tagtagaaga atttatgccg ggaacggaat atcgtttctt tgtgatcgac ggagaagtcc
    72781 aagccatcat gttgcgagtc cctgctaatg ttattggtga cagtatccga acagtgaaag
    72841 aacttgttga agaaaaaaat agtgaccctt tgcgtggaac gaatcatcgt gcacctttag
    72901 aattgatcca attaggtgaa ttagaacaat tgatgttgaa agaacaaggg ttgacgatcg
    72961 aatcagttcc ccaagccaat caaattgttt atctaaggga gaactcaaat atcagtacag
    73021 gtggtgattc gatcgatatg actgatgaat tttctgaagc ttacaaaaaa atcgccgttt
    73081 ctgcggtaga agcactagga gctaagatta gtggtatcga tttgattata ccagataaag
    73141 aaatcgatcc tacaactgat aaaaaagcat atgggatcat cgaagcaaat ttcaatccag
    73201 ccatgcatat gcatgtttat ccttttgcag gaaaaggcag aagattgacg atgaatgtat
    73261 tgaaattgtt atatcctgaa gtattttaaa agaaaaagct tttgacagat tgtcctattt
    73321 gatgtcaatc tgatcaaaag ctttttttgc atgtaaaaat ttatgtgttt tttcgtttta
    73381 aaataaacga tcccagaagc tttttttctt ttttggtttt tctttttcag ctggcgaaga
    73441 gttttcttct gggtattttt tttcgatatc aatcacaggt tcatttactg cttcttttgc
    73501 tgttaagagc aatccgaatt cctcaggatt tgcagtgacg taatcgttga ctacagtgaa
    73561 acggctattg tttttcgttg ctagctggat atattggttt tggacagaaa ggggtagagc
    73621 cccattcaag agtatggaag catctggatg ttttttgagt tcttttaaaa agttttcttt
    73681 gttttttggt tggatcattt cagcaacagt catactaaga tagcagcgtt ccctgaatgt
    73741 ccctaaatat ttatgctgtt cttcagggtt cactaaaggt gtaccataaa gtcccttatc
    73801 caaatggctt tttacatcat cttgtgccat aaaaaatacc ctccttcttc tctttgtctt
    73861 tcttacgatt atagcatatt cccaataata cctaaaacat atgaaaaagc ggttgctttt
    73921 gttcaacgat tcacttaaaa taagaatgaa aatcattctc aattagaaag gtggattgga
    73981 tgcgctacgg acgactagta gcattattag ttattttaag tagtatttca ttgttcatcg
    74041 gagtatcgaa tgtacaattg tcagaactgc tccagttaga tgggcaaagc ttacaaatct
    74101 tgctagtgac tcgtttgcca cgaacgattt gtttgatcct tgtgggagcg accagtagta
    74161 tttgtgggtt gatcatgcaa catttgaccc aaaataaatt tgtttcacca acgactgcgg
    74221 gcacgatgga tagtgcgcgt ttaggtattt tagtggctat gattttccta cctggtgcat
    74281 ccttgattgt ccgatccttg acagcatttt gctttgcttt tgcaggaaca ttgctttttt
    74341 tatcccttac gcgattgttc ctccagaaaa atcaattgat gcttccgttg attggagtca
    74401 tgttagggaa tatcattggt tcagttgcta ctttttttgc ttatcaattc cagttggtac
    74461 aaaatatgac ttcatggctt caagggaatt ttgcgactgt gatacgagga aattatgagt
    74521 tattgtatgc tgttgttcca ttgttgctct tggtttggct atttgcttac cgatttacga
    74581 tcattggtct gggcgaatcg tttgcagtaa atctgggaat agattaccag aagatgcagt
    74641 ttttaggcat tggcttagta tcattggcta gtgcagtcat gttgatcatg gtaggaagca
    74701 ttccttttat cggagtgatc attccgaatc ttgtctctag aatatatgga gatcaagtgc
    74761 acaaaacaat tggcgtaact gctttagcag gtagtttgtt cttagtattt tgcgatcttg
    74821 tcgctcgcgt gttgattttt ccttatgaaa taccagtcag tgtgatcgtt ggaatcatcg
    74881 gtggggctat cttcctttat cttctgataa ggggacgacg atatgcttaa aaaaaagcca
    74941 tctattttta ttggtatgct tgttcttgtt ttatttgtta caggaatgta cttgacgatc
    75001 catacatatg gaaactggca ttttgcatgt gcattgagga gtaagaaaat ttttgcattt
    75061 atccttgtct cgctagctgt cagcagtgcc acaatcagct ttcagacaat tacgcataac
    75121 cagtttttga ctccttcagt attgggactt gagtcgttat atgtccttgt ccaaacggtc
    75181 cttttcttct ttatcggagg agtgacgatg cttcagcaga caggtacagt ttttttctta
    75241 ttgaacgttg ggctgatggt cgggctgagt ctattgttat ttttctttct tttgaaaaaa
    75301 atgagagcga atcttttttt attactgatg tcagggatga ttttaggtac gctttttggt
    75361 agtgtcagta cctttttaca agtcatcatg gatccgaatg aatatgattt gcttcaaggc
    75421 agattatttg caagctttgg caatatccag agtcagtatc ttttgcctgc ttctttgatc
    75481 attatcggct gctggtacct gttatttcga tatcgacatg tgctagacgt tttccatctc
    75541 ggaaatgaac aagcagtaaa cctcgggata gacacagatc gttttgaatt tttgatttta
    75601 tgttgtgtca gtcttttgac agggacatca acggctcttg tgggtccagt tactttttta
    75661 gggtttattg tcgcaaatat cagttatcgt gtcttttcta cttatcgtca tggtcagcta
    75721 tttatcggaa gctttctggt agctatgctg tttctgacag gaggacagct cgcagtagag
    75781 cagattttcg gctggaatac aacagtgagt gtcgtcgttg aatttgtcgg aggaatttat
    75841 tttgtcacaa aattgattcg cgaaaggaag agtatcctat gattgattta caaaaggtca
    75901 ataaactgta ccatggaaaa tcagtggtta aagatgtaca gttaacgatt cctgaaaaga
    75961 aattgactgc ttttatcggt ccaaatggtg ctggaaagtc aacggtgttg tcgatgatca
    76021 gtcgtttgat accaaaagat acaggtgaaa tctatttaga ccataacgaa gtaaaggctt
    76081 ggaaatccaa tgaattagcc aaaaaattat cgatcctacg acaatcgaat gaaataaatg
    76141 tccaaatcac cgtgaaagaa ttagtagaat ttggacgatt tccttatacg aaaggaaaat
    76201 tgacgacaaa agacgaggaa atcgttcagg aatcactgga acaccttggg ttagaagaaa
    76261 tagcggatca atcgattgac actctttcag gcggtcaact ccaacgtgcg tatattgcaa
    76321 tggtgctagc gcaagacacg gattatattt tactggatga acctttgaac aatctagata
    76381 tgaattttgc ggttcaaatc atgcagattt taaaaaattt agtacaagaa atcgggaaaa
    76441 caattgttat tgttcttcat gatatcaact ttgctgcaag ttatgcagac gaaattgttg
    76501 caatgaaaga tggacagtta tttacgcaag gaacgaccca agaaatgata aaaaaagatg
    76561 tattggatga attatacgaa atggacatac ggatttgtga gattgaaggc cgcagattct
    76621 gtctttattt ctaaaactaa cattaggaga gaagagatga aaaaattagt agtaggtatc
    76681 ttgattctag catcatttgg tttagcagca tgtggaaata gcaacaacac cagtcaggca
    76741 gacacaaaaa aaagcagcac acaaactgaa actacattga cgataacaga tagtaatgga
    76801 gaccaaatcg aggtgccaaa taatccagaa aaagtcgtcg tattcgacaa tggttcttta
    76861 gatacgatgg atgctcttgg tgttggagat aaggtagttg gagcagctac aagcagcctt
    76921 cctgagtatc tttcatccta taaaaaagta gaatcagcag gtggaataaa agaaccagac
    76981 ttagaaaaaa ttaatcagct tcagccagat ctaatcatca tttctggccg acaaagagat
    77041 tttcaaaaag atctaagtca aattgctccg accattttcc tttctttaga tgcgaaaaat
    77101 ccatgggaat ctttccagca aaatgtcact gctttagggg agatctttgg taagcaagaa
    77161 gaagctaaaa ctcaattaga ggaattatct agtgcaatcg atcagacgaa aaagaaagca
    77221 gaagctactg acaaaaaagc actagtcaca cttgtgaatg aagggcaatt atcagcctac
    77281 ggatctggtt ctagattcgg tttcatccat gatttatttg gctttgaaca agcagatgat
    77341 caaatcgaag catccactca cggtcaaagt gtttcttatg aatatgtgct ggaaaaaaat
    77401 ccggatatct tatttgtagt agacagaaca aaagctattg gtggagacga cagcaaagat
    77461 gatatttctg ccaatgaact ggtagcacaa acgaatgctg gtaaaaatca gcagatcatc
    77521 tcccttgaac cagatgtctg gtatttaagc gggggcggtt tagaatcaat gaaactgatg
    77581 atcgaagatg tgaatcaagc atttaaatag cataaataac agaggattaa actctcatac
    77641 tatgtaacaa taatgtttct tacattctta aatagcaaga gcctatcctc aaagaagtta
    77701 tcaaaaacca tccgtaaaat cgtattgatg attttacgga tggtttttat ttatttgaga
    77761 aatctttttt caacgtgaat tcattatcta catcatacgg gttgattcta gaatggggag
    77821 tggcaaaaaa tagtgtgatc cattttttca gcatcaagat cgcctccttt gatttgaatc
    77881 aaaggtacaa agcgaaactt agataaaact taaatttaga tatttttatt ttgtaccgat
    77941 ctcttcttta aacgatgttc catctgctgc ttctcggcaa taagtccact agactagaaa
    78001 atatgagaag ctattttctg tccagcgttc ttattactca aagcaaatcg cagttgtcac
    78061 aatctcttct aaacgatgtt ccatctgctg cttctcggca ataagcccac tagactagaa
    78121 aatatgagaa gctattttct gtccagcgtt cttattactc aaagcaaatc gcagttgtca
    78181 caatctcttc taaacaatgt tcaatcagct gaccttcggt attagctcaa agcactgatt
    78241 tcacaacctc tatttaggca tgtgtctcag caagcggttg atagttgatg atctgcattt
    78301 ttcgataaaa atcggcggga agcttactcc accgttttaa taattgatag aaataactct
    78361 cttctgcttt gattttatac tcgcttaata tcaatccaaa actattcgtt ttttttgaag
    78421 ctaatttttt ataaatatcc aatgctttgg ttttatcttc attgacaaag agtgttttta
    78481 cttcaatata agaaccctcg atattttgtg tttcttcgat aaaatagatg ttttttatat
    78541 attccttcat agtgattcct ccaaagaagt cttttatttg ataagtttac tctaccgaag
    78601 agttgttaat aatccgtgaa caaaaagtaa ttctttttcc aatagttgtt aaaggttttt
    78661 tattttttat agtatttttt gttatttaag aaaggaataa ggttaaacaa ataacaggtt
    78721 gctttttggg tctttttccg ttcaagaaac tgaacgaaga aaagggaaag ttgtctcttt
    78781 tgtgataaga gaaatcataa taaacgaatg acttactttc caataaattg agaacagtca
    78841 gaaccagaca aattagttgc atctgatgaa taaagtgatt attctatgac atgaggtgat
    78901 acagatgaaa ttagaagtga caaaagaagc acaagaagta ttgaagaata aattagaagc
    78961 agacgatcaa cttttattag atatcgaaaa cggtgacggt ccatttgcag aaagccaagt
    79021 cagttgccaa ttggatacgg catttcgatt gatcattgtc aaaaaagata cacaaacaga
    79081 tctaagtctt tattctgtag tggctgatac accagttgga ccaatcaaaa tcaaagacag
    79141 tgcaatactt tacatggatg atccatccac acttgcttta gaaccaactt ataatagttt
    79201 acaattaaaa ggaccaagcg gcttgagaaa aggcaacttg caagttgttc gaaaagacta
    79261 gagggataaa atgggaaaat tggcgatcat cagcgaccta catgtggaca tcaataaatt
    79321 cggcgaatca gagctgatgc agctttggca agttttgcaa aagcacaaga tcactcggct
    79381 tcatctagcc ggagatacgg ctaataaagt agaccgttgc ctagctgttg tcgaattttt
    79441 cgtcaataaa ggattatcta cgacatttca tttcggcaat cacgagttgg cagatgtgcc
    79501 caatgaacag atgatggacc attttccaga cccacatttt ttaaatgaac ggtatattgc
    79561 tttaaatgag cagaccgttc ttttagggat gaatggctgg tacgactatc agttttccga
    79621 attgaaagat tacgaggcaa tcgtacgaat gaagcgtttg tattggtatg atcggttcat
    79681 ccagcgtggg aaaacagatc tcgaggtcaa tgcagaaatg cttgcagctg caaaaaattt
    79741 gctagaccag ctggaagcaa aaaaacttga ggtgatttta tccactcatt tcgttcctaa
    79801 acgggcattt atcatgtatc aatctgctcc ttatgagcgt tggaacaaat taaatgcatt
    79861 tttaggatca gaatcattcg gagaattact tgaccgttat tcaaatatca aacaagtagt
    79921 ttttggccat acgcatcgtc gctttgaaga taaatccatc ggtcacacga tttacagctg
    79981 cagacctttt ggttattatt atgaatggca gctgacccga gattttgtct tgaaagaaca
    80041 gttgctagac agctatgatc ctatgaaatt acgtgtcctc ttgcgtgccc atcacccagc
    80101 ttttcaggcc tatcaaacac aacatttgca agaggaattt gaacaagcga tgacaatcgt
    80161 tccgtattga gacagcatta gtaatgtgta aaagaaaata ccttgtaaaa cataaggata
    80221 agtaagagca gtagatccat ttatcgtgga tatgctgctt tttttgcgga aaataatcag
    80281 cgaatgttta tttgatcgga tgatttgtaa ctcgcagagt actagatgca agcgtgtatt
    80341 ctttttttga acgataatca caaaaaaaaa tataatatac attttttatt taattataat
    80401 taatattgat tgaagtctag gcagtcaagt cacattttga tagataggag ggggacttac
    80461 gaattatttt aaaggctatg acagctgtat ttctagattg tgtttgcatc aagttgcaat
    80521 aaaaactaga aatcaaatcg ggctgataat catttataac taatcgatac ataggaccaa
    80581 atataggtct atgttctttt atttcataag tatcgtaaaa cagaattttg ctatggatta
    80641 atccaatcga ctgatatgtt tagtaaataa agaaagagga atgtcaatga tgaaaaaaga
    80701 aatcgtatta acagcagcaa tgatgttatt cagcatggta gcaagtacga cttttgtttc
    80761 tgcaactgaa gtatacccaa aggaatataa cacagaagga acgattacat ttgaagcagg
    80821 agatgagggt gtaactcctc ctgttgatcc agagaatcct gatcccaata aacctgtcga
    80881 tccatcagat cctccaagcc ctggaacagg aggggcatta tcgattgatt atggatcaaa
    80941 attcaaattt gggactcaaa aaatttctac tgcggataaa acgtattatg cagctgctga
    81001 tgtgatgaac gatgggtcta gaaaaccgac atatgtccaa gtgacagata ggagaagtac
    81061 cttatctggg tggaaattaa gtgtctctca accagaacag tttaaaactg ccagtgggga
    81121 tgaactagtt ggagcacagc tgaaatttac gaaagggcag gctgtttctt tggttgatcc
    81181 aacatatacg ccgcaaacgg tgaattctga attaacgttg acaccgggag gaaacaatac
    81241 gttagcaatt aatgctaaat caggaacagg tgtggggact tgggtctatc gatttggtgc
    81301 aaatgaaaat gaaaatcaag atgcggtaca gctttcggta cccggtaaat ctgtcaagtt
    81361 agcgcaacaa tattccacta aattagtttg gacattagaa gatacaccta acaactagtt
    81421 tactgaaaag aactgttaaa aataaatacg tagtcatatt gtcttgcgag gtaatcgagc
    81481 aaaaattgtc aaaggctagg ctaaatttgt ttggatacga atagttcatc taggaattta
    81541 acgatcagga ggaaaagata tattgaaaaa gaggaggatc gtgctcattt taagcagtct
    81601 cttagtgact aatatctttc cgatcatagg gtactctttg gaattgaatc agttggagca
    81661 tggaaataga agagacgaag aaagcaaact cacttcgaca ttcgacagtt taatagaatc
    81721 caaccagaca caagaaagca gtgaggattt aagtatttcg agtagtggag agaccactga
    81781 caacgtagaa gctgagggtt cggacaaaca aggactagaa gatgcaccaa tttctgcggt
    81841 tgagctgcct gacgatccca atattatttc tatcgataaa atttttcaaa cacctatcgg
    81901 tactagcacg tccatattgg aaaatgggaa gttactgcag ttgaacccag cagaaaggtc
    81961 tcaaagagga gctatttggt caaataagaa gattagttta ctctcggatt ttacatttaa
    82021 atcttattta tacttaggaa atcaacgaga tagagcggga gatggcatga cctttacatt
    82081 gactggcgat cctagaatgg ctagtaatcc cagtcaagtt attggatcgc caggtatggg
    82141 aattggctca tattctactc gttctggcca accttacatt gcgaatgcgc tctcgattga
    82201 gtttgatacg tataaaaata gtggttcttc tgatcgaatg gatcgagaga taactgctga
    82261 taatagaggg catggacatg tcgcttttgt cacgcctaaa ccaaataata ataattattc
    82321 tggagagcat actggcgtga cggtagctcc tacatttctt tctaatggca catggcgctt
    82381 gttaataatt aaatgggacg cggagcaaag aagtcttact tatgatttgg aaggtgtcgg
    82441 tcactcttct cggattatac ctgatctcat taggcagttt ggttctacag aagtaaattg
    82501 ggggtttact tcttcaacag gtactttttt tcaagaaaat gctgtcgctg tcacgcgact
    82561 tccatcgaat gtcacatcaa cagctgatgt aaaagtcaac gatagtgatt atggggccat
    82621 cgctgaagct ggaggaaacg ataagataac tatcagaaat acattgaagg tcgaggggga
    82681 ttttcttgaa tataagaaaa tgcagactag tatcgacctc ccacaagaat taactattcc
    82741 cgagcatatc ttgatcaatg gaaatcaaat tgatgccaaa gatatcttga taaccggaaa
    82801 tcgagtcacg ctaaatctga cagattattt tattgctgga gatacgttaa taatcgaatt
    82861 ggagacaact ttgcaggaag taattcctga aaaagtactc actatgcatt ttgaatacct
    82921 tgaaaacggg aatttgattg agcaatcgaa tgaaataaac ctaaagatcg caaagctgaa
    82981 ggagatagat atccatgttt attataaaga taaagacagt cagattgata ttgctgaaat
    83041 gaaaacaatc actgggaaaa taggagagaa gtataaagaa actcctattg atattgaagg
    83101 gtatgttttt gactcggatt cagcgaatac agaaggcatc ttctccgaaa atacagagga
    83161 tatctatttt tattacagaa aaggcaaact ttatctctca actgctcctc aatatgtcaa
    83221 ttttggaaaa cataaaatat ccagtagacc attaagtgaa ttcggacagt tttcaggtgg
    83281 gttgaaaatt atagatgaac gggcttttgg aagttggaaa ttacaattga aacaagagaa
    83341 agttcttaca aatggagatt ttgagcttcc agaagctctt tcctttgtta cctctgaaaa
    83401 tacaacggtt atagggacat ccgctgttac gattttcgaa agtgatcaaa agggtgaaag
    83461 cgatttgtcc tctcttttag attctacagc tcatcgtgga atcagaatag atattcctgt
    83521 agaaaaccaa agaatcggaa cctttgaggg gaaactatct tggatacttg cagatgtccc
    83581 aggaaattaa caggaagaga agaatataac aaaattattg agtttcaaga agggcacagg
    83641 taccataggc tcttgtgtcc cacagagaca agattttgtt atagtcttct cttacatatg
    83701 attaaaggag cgattttctt gagaccaaaa caacaattat ttataacact cctagttatt
    83761 ttaggggcac tttttaacaa tatatcagtg tcagctagtg catttaattt ttcagtgacg
    83821 ccgataactt cagagaatca aatcgacaag agaaaaactt acttcgatct tcaacttgat
    83881 ccggatcagg aagtagaagt aaaagcggaa ttgagaaatg atacagaaaa agaagtgaaa
    83941 atcgatattt ctgtgaatag cgcaaccacc aattcaaatg tgatggttga atacggaaaa
    84001 aacgagattg aaaaagacat gagcctgatc tttgatctgg tagattatgt gagctatcca
    84061 cagatagtga cgctaaaacc taaaagtgtc caaaccgttg cttttcatgt caggatgccg
    84121 aatgagcgat ttgatggtgt attggctggt gggatcacat tccaagaaat ccagacggaa
    84181 aaggaccaaa cagaaactaa ggatcaaagc ttatcgattg agaatgaata cacctatatt
    84241 attgctttgt tgatgcaaca gacactgaac gaagttgctc cgaaccttac tcttcatgaa
    84301 gttaaaccag atcaaatcaa tgcaagaaat gtcatcttag caaacgttca aaatgatcaa
    84361 aaaacctata tcaatcaagt agttattgaa acaaaaatta caaaaaaagg acattctgaa
    84421 gttttatatc aagaggaaaa agaaggattg cagattgcgc cgaatacaaa tttttctttt
    84481 ccaactgctt taaatggtca accgctaacc ccaggtgaat atcaccttac aatgactgtt
    84541 ttaggaaatg aaaatgaaaa tggaaaattt tcgagaaaaa aaggaaatac tacgatcaac
    84601 tataccaatc aatgggtatt tgaaaaagat tttacaatag acggaaaagt agccaaggaa
    84661 ttgaacacga cggatgttac gattaaaaaa gacaataatt ggatttatat cttagtagct
    84721 tcacttttct tattgtttat tttattatgc atacttttgt ttgttttgag aaaaaaagaa
    84781 gagaaagaaa agtaaggtta agataacaaa tagtaaattt ttattattgt agga
//
LOCUS       DAJSMK010000004        74739 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.004, whole genome shotgun sequence.
ACCESSION   DAJSMK010000004 DAJSMK010000000
VERSION     DAJSMK010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 74739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.004"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(23..388)
                     /locus_tag="ON488_000267"
     CDS             complement(23..388)
                     /locus_tag="ON488_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230489.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYAVCIIKRDK"
     gene            complement(563..2698)
                     /locus_tag="ON488_000268"
     CDS             complement(563..2698)
                     /locus_tag="ON488_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3230490.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(2781..4436)
                     /locus_tag="ON488_000269"
     CDS             complement(2781..4436)
                     /locus_tag="ON488_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCR3230491.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(4438..4752)
                     /locus_tag="ON488_000270"
     CDS             complement(4438..4752)
                     /locus_tag="ON488_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCR3230492.1"
                     /translation="MNLLFQSIKSITVPELKEKILENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            4922..5182
                     /locus_tag="ON488_000271"
     CDS             4922..5182
                     /locus_tag="ON488_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HCR3230493.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            5196..5510
                     /locus_tag="ON488_000272"
     CDS             5196..5510
                     /locus_tag="ON488_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HCR3230494.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(5995..6549)
                     /locus_tag="ON488_000273"
     CDS             complement(5995..6549)
                     /locus_tag="ON488_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HCR3230495.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(6675..8603)
                     /locus_tag="ON488_000274"
     CDS             complement(6675..8603)
                     /locus_tag="ON488_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HCR3230496.1"
                     /translation="MDNEMISQLQFDRIKKEIQARAIGNYSKKRISDMTVSTNLQTVL
                     DRQEETREARLILESSQHVPFMGLPRIDALTEQVKKGLILQPTDLIEYADFLRSSRMI
                     TKFFDKNQYQTPLLFAYSKHLPDLINVEELIDQKIKNNKVSDDASRNLRKVRKQLQLI
                     EKEIQSKLLKFLRHPKNKEMIQEAMIVQKGEYYTIPIKASYKNKIDGTIIDESNKRTT
                     VFIEPTVISKLNEHYQLLKAEEISEEYQVLAALTGAIAENEEVIDLLIETITVLDIIF
                     ARAKFSREINGSTPRINKSEHIIIKQGRHPFLPEHAVPLDVEIGKDYRGLIITGANAG
                     GKTVVLKTVGLLTLMAMFGMQVPAKEGTELAVFDEIFVDVGDHQNLENALSTFSGHMQ
                     NIAAILKKIKRNTLVLLDEIGSGTEPNEGAALAIAIMESMYEQGALIIATTHYGEIKK
                     FAGDHEDFVPAAMAFDREALRPKYQLRVGETGESQALWIAHKMDMSMKLIHQAERYLA
                     EKAYRTQKKEFLPKTAVTNRKENKKERQLFAKGDRIFVNEYQKEALVYEDIGEDTIDV
                     YLDKKIIHVPRQRVRLVRSAEDLYPTGYDLDSLFIDYKTRKRQRDLERGSKKAHKVLV
                     KEMRKRQEERRVNDENSK"
     gene            complement(8909..9625)
                     /locus_tag="ON488_000275"
     CDS             complement(8909..9625)
                     /locus_tag="ON488_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCR3230497.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="ON488_000276"
     CDS             complement(9626..11449)
                     /gene="glpO"
                     /locus_tag="ON488_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HCR3230498.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="ON488_000277"
     CDS             complement(11463..12959)
                     /gene="glpK"
                     /locus_tag="ON488_000277"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HCR3230499.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(13095..14555)
                     /locus_tag="ON488_000278"
     CDS             complement(13095..14555)
                     /locus_tag="ON488_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3230500.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(14545..15840)
                     /locus_tag="ON488_000279"
     CDS             complement(14545..15840)
                     /locus_tag="ON488_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCR3230501.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVKEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(16172..16849)
                     /locus_tag="ON488_000280"
     CDS             complement(16172..16849)
                     /locus_tag="ON488_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HCR3230502.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(16879..17970)
                     /locus_tag="ON488_000281"
     CDS             complement(16879..17970)
                     /locus_tag="ON488_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HCR3230503.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(18071..18505)
                     /locus_tag="ON488_000282"
     CDS             complement(18071..18505)
                     /locus_tag="ON488_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3230504.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(19089..20546)
                     /locus_tag="ON488_000283"
     CDS             complement(19089..20546)
                     /locus_tag="ON488_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCR3230505.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENL
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIEDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(20543..22438)
                     /locus_tag="ON488_000284"
     CDS             complement(20543..22438)
                     /locus_tag="ON488_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3230506.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPITLLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSPVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(22496..24271)
                     /locus_tag="ON488_000285"
     CDS             complement(22496..24271)
                     /locus_tag="ON488_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCR3230507.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYLVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESSEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(24321..25817)
                     /locus_tag="ON488_000286"
     CDS             complement(24321..25817)
                     /locus_tag="ON488_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCR3230508.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     EIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRIWKEEDCAPVMLDGDEQYLQANTVDYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(26011..27633)
                     /locus_tag="ON488_000287"
     CDS             complement(26011..27633)
                     /locus_tag="ON488_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCR3230509.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESINAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTVPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(28083..29396)
                     /locus_tag="ON488_000288"
     CDS             complement(28083..29396)
                     /locus_tag="ON488_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCR3230510.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCILMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLLGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFMGFMWILNVK"
     gene            complement(29641..29865)
                     /locus_tag="ON488_000289"
     CDS             complement(29641..29865)
                     /locus_tag="ON488_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230511.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(29885..30307)
                     /locus_tag="ON488_000290"
     CDS             complement(29885..30307)
                     /locus_tag="ON488_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HCR3230512.1"
                     /translation="MESVYRQERKSNRKKGQTMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGVLTFNFSDPEGNYFVIGKAESSD"
     gene            complement(30449..31159)
                     /locus_tag="ON488_000291"
     CDS             complement(30449..31159)
                     /locus_tag="ON488_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230513.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGDESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(31177..31673)
                     /locus_tag="ON488_000292"
                     /pseudo
     CDS             complement(31177..31673)
                     /locus_tag="ON488_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(31710..32162)
                     /locus_tag="ON488_000293"
     CDS             complement(31710..32162)
                     /locus_tag="ON488_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3230514.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(32297..32902)
                     /locus_tag="ON488_000294"
     CDS             complement(32297..32902)
                     /locus_tag="ON488_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCR3230515.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(33352..33972)
                     /locus_tag="ON488_000295"
     CDS             complement(33352..33972)
                     /locus_tag="ON488_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HCR3230516.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(33974..34843)
                     /locus_tag="ON488_000296"
     CDS             complement(33974..34843)
                     /locus_tag="ON488_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HCR3230517.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANKAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(34866..35273)
                     /locus_tag="ON488_000297"
     CDS             complement(34866..35273)
                     /locus_tag="ON488_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCR3230518.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDRHKLAELYEQVGLKFSELHENDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(35292..36581)
                     /locus_tag="ON488_000298"
     CDS             complement(35292..36581)
                     /locus_tag="ON488_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3230519.1"
                     /translation="MSVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINDQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     ILLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(36608..36910)
                     /locus_tag="ON488_000299"
     CDS             complement(36608..36910)
                     /locus_tag="ON488_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3230520.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(36935..39028)
                     /locus_tag="ON488_000300"
     CDS             complement(36935..39028)
                     /locus_tag="ON488_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCR3230521.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLEEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(39517..40245)
                     /locus_tag="ON488_000301"
     CDS             complement(39517..40245)
                     /locus_tag="ON488_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HCR3230522.1"
                     /translation="MGLCLFALPTQGFAVAGGHGGGTSSGRSSGRGSFGGRSYGGSYF
                     GSRSYGRDSYGYYGPSTGPSSYEQTGFLALAVLSVGGVSAFSIVKNKRQKKRLKSEIL
                     SRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFAEHQKVLQKNKAD
                     GVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLISGSKTQRQYFSQ
                     IWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(40391..43012)
                     /locus_tag="ON488_000302"
                     /pseudo
     CDS             complement(40391..43012)
                     /locus_tag="ON488_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298916.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
     gene            complement(43126..44457)
                     /locus_tag="ON488_000303"
     CDS             complement(43126..44457)
                     /locus_tag="ON488_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3230523.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRVMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKANFGQLNELVPFGFAGMIASFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKNAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQSGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFVGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(44423..45901)
                     /locus_tag="ON488_000304"
     CDS             complement(44423..45901)
                     /locus_tag="ON488_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3230524.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLKNPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(46206..48041)
                     /gene="tdc"
                     /locus_tag="ON488_000305"
     CDS             complement(46206..48041)
                     /gene="tdc"
                     /locus_tag="ON488_000305"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCR3230525.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEQVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     EQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKEIAKAMEKKLNEIIQ"
     gene            48268..49227
                     /locus_tag="ON488_000306"
     CDS             48268..49227
                     /locus_tag="ON488_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HCR3230526.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(49313..50407)
                     /locus_tag="ON488_000307"
     CDS             complement(49313..50407)
                     /locus_tag="ON488_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCR3230527.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            50596..51357
                     /locus_tag="ON488_000308"
     CDS             50596..51357
                     /locus_tag="ON488_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCR3230528.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(51472..51912)
                     /gene="fabZ"
                     /locus_tag="ON488_000309"
     CDS             complement(51472..51912)
                     /gene="fabZ"
                     /locus_tag="ON488_000309"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCR3230529.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            52132..52887
                     /gene="fabI"
                     /locus_tag="ON488_000310"
     CDS             52132..52887
                     /gene="fabI"
                     /locus_tag="ON488_000310"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HCR3230530.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(52997..54010)
                     /locus_tag="ON488_000311"
     CDS             complement(52997..54010)
                     /locus_tag="ON488_000311"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HCR3230531.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            54175..55095
                     /locus_tag="ON488_000312"
     CDS             54175..55095
                     /locus_tag="ON488_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HCR3230532.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(55375..55875)
                     /locus_tag="ON488_000313"
     CDS             complement(55375..55875)
                     /locus_tag="ON488_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCR3230533.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(55982..56500)
                     /locus_tag="ON488_000314"
     CDS             complement(55982..56500)
                     /locus_tag="ON488_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCR3230534.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(56501..57856)
                     /gene="rph"
                     /locus_tag="ON488_000315"
     CDS             complement(56501..57856)
                     /gene="rph"
                     /locus_tag="ON488_000315"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HCR3230535.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(57859..58680)
                     /gene="racE"
                     /locus_tag="ON488_000316"
     CDS             complement(57859..58680)
                     /gene="racE"
                     /locus_tag="ON488_000316"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HCR3230536.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(58842..59498)
                     /locus_tag="ON488_000317"
     CDS             complement(58842..59498)
                     /locus_tag="ON488_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCR3230537.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(59514..60161)
                     /locus_tag="ON488_000318"
     CDS             complement(59514..60161)
                     /locus_tag="ON488_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCR3230538.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMTIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(60174..60989)
                     /locus_tag="ON488_000319"
     CDS             complement(60174..60989)
                     /locus_tag="ON488_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCR3230539.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(61003..61740)
                     /locus_tag="ON488_000320"
     CDS             complement(61003..61740)
                     /locus_tag="ON488_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCR3230540.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            61994..63004
                     /gene="trpS"
                     /locus_tag="ON488_000321"
     CDS             61994..63004
                     /gene="trpS"
                     /locus_tag="ON488_000321"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HCR3230541.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            complement(63174..65594)
                     /locus_tag="ON488_000322"
     CDS             complement(63174..65594)
                     /locus_tag="ON488_000322"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HCR3230542.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(65599..66642)
                     /gene="pheS"
                     /locus_tag="ON488_000323"
     CDS             complement(65599..66642)
                     /gene="pheS"
                     /locus_tag="ON488_000323"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HCR3230543.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            complement(66951..67292)
                     /locus_tag="ON488_000324"
     CDS             complement(66951..67292)
                     /locus_tag="ON488_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3230544.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            complement(67361..71083)
                     /gene="addA"
                     /locus_tag="ON488_000325"
     CDS             complement(67361..71083)
                     /gene="addA"
                     /locus_tag="ON488_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HCR3230545.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            complement(71080..74607)
                     /locus_tag="ON488_000326"
     CDS             complement(71080..74607)
                     /locus_tag="ON488_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HCR3230546.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
BASE COUNT        21395 a        15933 c        12654 g        24757 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtattcaa
       61 aagatttatt tacttttttg tatagatttc gattgttcca cctagtcaat acaaatgagg
      121 taatcaggaa actgaaaaaa atcaatacaa aaaagccgat taagaaatac agcattttct
      181 tttctgataa aaaagcgtac aaggaaaaat ccttggctct ttctggtctc gttaatggga
      241 aaaagaccca tataaaagga agaacaacga tcatccatcc taaaagagcc actaacgttt
      301 gccaaatctt taaccagtaa ttaccttttg aaaaatactt atctttcacc aaaattgatg
      361 caacttcttc tcttgttact tttttcatat cctcacctca cgtttttttg ttacgacgta
      421 ggagtttacc atacatttca tttcttttca cataaagtgt tcctaaattt ttcctaagaa
      481 aaagaacaaa acatttctca tcagcaaatg aaaaatattt tgttcttttt atcagttgtt
      541 ctttttattt tttatctctt aattatgttg ctctttccaa tacgacaatg cttttcattc
      601 ctctagatat cgccgtgtac atttgtctgc gtcttctttg ctcatctcca tcgttttcaa
      661 atggatataa gattacatga tcaaattcca gtccttttgc tagactcaaa ggaatgattt
      721 ggcagttttc taatccatat gaattttttt taatcgattc ttgtagcgtt tgggtttcct
      781 cttctgtttg ggtgataact gccgcttttt ctccttttag agaaaccaaa atctcagcta
      841 gtattttcaa caattcttca gaggatcgaa aagagcggta ttcgggttct tttccttgcg
      901 gtcggatcga tacgatgtcg atcttctctt gatccacagc ataggttttg aaaagctctg
      961 tgattgctcc gctagaacgg taactatttc taagatcata ccgatggatc ggcagatggt
     1021 agtcatcgaa acaacgcata atatcagcaa aagtagtgga agaattaaag attgcctgat
     1081 tctcgtcacc tactaaagta aagtgagttt ttggaaataa ttcgatcaat agacctaatt
     1141 gtgccagggt ataatcttgt acttcatcaa tcaatagata gcgaaatgct ggtacattta
     1201 ccttttcaac aagtaaatga cgaatagcta atataatgac tgcttcatca acagtacgtg
     1261 tgggttgcca agcataagct gagccatatc gtttttcata aattctttca aacaactgat
     1321 gctcatccac ccatgccatt tcttcgattt gtctggttat ttttcgatat tttttttgta
     1381 aaagtttcct tgcataagct acaatacttt gttccgaatc atcagaaatc aatttaccga
     1441 ataattccaa ctgcctatct tctgtcaacg agagtacctg attctgcaca gcaggacttt
     1501 ttgcttgttt caaaagatga ttcttccatt cgctcatcag tgcctttttc gttgcttgaa
     1561 gcctatcgat caatttagga tgagcaggaa ctttctcata tattttttcg atcgtttttt
     1621 tagaaaggac tgtttttcca tttttagtaa gtccacggat aaaattcgga tgatctaaaa
     1681 acaaaggatc tgattgtttt agattatcga taaacttttt gctacgcaaa cgttctgtct
     1741 gctccgatac attttctccc gtgatacgtt tgaaataagc ctcttcacct tctatttcct
     1801 ctgctgaaag ctgtgaaacc agctgtatga tggttagatt cagtggattt ctttcaccta
     1861 atgatggtag gacattcgaa atatagtcga taaaccgatg attaggtgat agaatcagca
     1921 agtcatcgga tgtcatcgta tctcgatata aatagagcag atacgcaata cgctgcatga
     1981 tagcagaggt tttaccactt cctgctacgc catttaccaa gatattttga cttttcacat
     2041 cccgaatgat tgtgttttgt tccgattgga tcgtagcagt gatagccttc atttcattgg
     2101 tctcatcttg gcctaagact tctaataata cgtcatcttg aatagctaca gacgtatcaa
     2161 aaaacttgac caaacgatct ctttccaaaa gaaattgtcg tctttcttta ataaccgtat
     2221 cgattttatt ttgacgaacc gtataagaag atggaccaat catgttattg taaaaaagtt
     2281 cggcaattgg tgaacgccaa tcataaacaa gattttcatc tgcatcatct gtgaaatttg
     2341 ctgtaccgat ataaaaggat tcttttggct cattatccag aaagtctaca acgacttttc
     2401 caaagtaggg acttttcaat aaacgttcga tctttgctag ctgattttct gcgtttttct
     2461 gtttgatatt catctgatcg atttctctat ttttcatttc aatcatcgaa aaagtatcca
     2521 ggttatctaa gtaactgtca aaattcaatc gaagctcgcc agccatttct ttcaacgact
     2581 ggtttccttc tatttttgcc gtatccatcg attcccgcag ttcgtttttt ttatcaatta
     2641 gcttttgata cacgttcttc agatatgctt cttctaactg tttttgtgtg ttgaccatac
     2701 acattctcct ctttttttaa agtggtggaa ccgattagtt tacctctttt aagagtcgaa
     2761 tgcaagcttt ttaacgagta tcatttgtta ggatatatca gttcttcagg tcggacagtt
     2821 tgatataaag aaaatgcacc atcaaggttt tttacgtggt agccagactg cttcaagatt
     2881 ctttccgcta gatagctacg taatccgcta tgacagctga cgatatattc ttgttggctg
     2941 tctaattcat ttaatcggtc ccgaagttca ttcaaaggga tatgtttggc ttccttgaat
     3001 ttgccctttt ccaattcttc tgctgttcgc acatctaata aaatttttcc ttttgctagt
     3061 tctgtcggca attcatgcca ttgtacggtt tcactaagcc cttctgcaat gttcattgct
     3121 gcatatccta gcatgtttac tggatctttg gctgagccaa atggcggtgc atacgtcaat
     3181 tctaattccg gtaaatcgaa gatcgtcaaa tgccctttga ttgctgttgc taaaatatcg
     3241 atccgtttat ccacaccttt tgccccaaca ccttgtgcac cataaatctc gccagtctct
     3301 ggatggaaga tcaacttcag taaaatatct gttgcttctg gataatagct tgcatgatct
     3361 tttcctgata catgaatgac ttcaaaagac agttcgtttt ctttggctgt tctttcactt
     3421 aaaccggtgg atgcggcagt cattccaaac gttcgtataa ttgctgttcc aataccgcct
     3481 tgatttcttc gagaaattcc ggaaatcgtg tccgcaactt gtctaccttg acgattggct
     3541 ggtgaagcaa gagaaataag tgcatctttt ccagtgattt gctgttttac aacgatagca
     3601 tcccccaccg cataaatatc aggaatattc gtttgataac gttcgtctac taggataccc
     3661 ccgcgtatgc ctaattcgat tccagcggtc actgctagct ggttatcagg acgaacacca
     3721 atggataaaa taactaaatc agcagggatg gtacgcccat catccagtcg caatcgtttc
     3781 ccgtggtctt caaatccagc gacagcatga gaagtaatca cttctactcc ttgatgagac
     3841 aattcttttt ctataaaagc tgccatttct tcatccagtg ttggaagaat atgtggtgct
     3901 tgttcgatca ccatgacttc taaacctctt ctttttaggt tttctgccat ttccaatccg
     3961 atgaatcctg caccaacgat cacggcacgc tttggctgtt tttctaatgc atgcatcact
     4021 ttatcgatat ctggtacatt tctaatagaa aaaacattgt cggcttctgt tatccctgga
     4081 atcgatggaa caactggttt tgcaccagga gataaaacca atgcatcgta ctgttcaatg
     4141 tgtttttgac cctcatgtac gacttctacc gttttgtttt cgggaaagat ggctgtcact
     4201 tcatgatttg gacgcacatc taaacaaaaa cgagcggata atgattctgg cgtttggaca
     4261 agaagatttt cccgttcact gatttctccc gaaagataat aaggcaagcc gcaatttgca
     4321 aaagaaacat acggtccttt ttcaaaaaca acgatttctg catcttccat taatcggcga
     4381 agccgtgtag cagcagacat tccacctgct acacctccga caataacgat tttcatctta
     4441 tttccctcct actgttcgat caaaccattg attcatgcca ccacgtacat tcactacatc
     4501 ataaccagat ttctttaatt ctttagctgc ttgtttactc ctcatccctg attgacaaat
     4561 cacatagacg gtcttttctt tgtctccatc atatctgttt atactttgta atggaacatt
     4621 tttagctcct tttatatgcc cgccccggta ttctgcaggt gttctaacat caagtaacgc
     4681 tggattttcc aaaatctttt cctttaattc tgggactgtt atcgatttta ttgattgaaa
     4741 tagcaaattc attttctgca cctcatttac atttttataa atacctcatg gggtatatta
     4801 aacaggagct ttattaatat gtcaaccaga atgactcttc atttttttca ctacttttta
     4861 tatttgcata aaataccgat aaggggtatt atctaattat aaaaatagag gagaatgtgt
     4921 tatggagatt gataataaaa atatcctgaa ccgtttgaaa cgtacagagg gacaaattcg
     4981 tggtatccaa aaaatgatcg aagacgaaaa agaatgtatg gatgtcatca ctcaattaag
     5041 cgctgttcgt tctagtattg atcgcgtaat gggcatgatc gttgcagata atctgaaaaa
     5101 ttgctttgag aaacctgata gtaatccaga agaacaagcg gctaaactag aacaagcgat
     5161 caagatgatt attaaaaagt aaaggaatga tttcaatgaa agtcgttttc catattgatg
     5221 aattagaaaa atggtcagaa acagggaaaa acgtaaaaaa cctgataaaa gcttctccag
     5281 aaacgacgat tgtcgtatct gtaaatggca tcgcgattac cggttatcta gactctgcca
     5341 atgcagaatt cttagatttg caaggagtcg tttttcacgc ttgcgccaat gctatgcgtg
     5401 ctaatcatat ttcagaaagt tctttacctg aacaagtaat cgttgtacca gcaggtgtcc
     5461 ttgatttagt tgaactgcaa tcccaaggtt atgcttatat caagccttag tcagtagagg
     5521 ttgcgacaga agtgatcagc ttcaagaaat ttcggcttat ttttcgaaga agctacttct
     5581 ggaaaaccgt gaatcaaagg ttgtgaaaac gctgtcctgc atcaagtaat aagaacagcc
     5641 aaacaaaaat agcttctcat atttttcgtt tggttgggct tattaccgca gatgcaagct
     5701 tttgaacacc gtttaaggaa gaggttgtga aatcagcggt ttgacctaag tattagagaa
     5761 aaaaacggga aaatagctcc tcatattttg ccgttttttg agctaatacc gaaggtcagc
     5821 tgattgaaca ccgtttacca agaggttgtg agcctaccat ttaactccga atcacaagaa
     5881 ataatttcaa aaacaacttc tcctgttttt ggtttggttg gcttattatc gagaagtagc
     5941 tactgggagt ctatttatca aaaaaaggaa tgcgacatag gtcacacccc ttttttattt
     6001 tctttgaaac atctttcggt actcgacagc atacaagaca aaagattgta aaagaccgta
     6061 agtgatgacg gcaaaaatga ctctcaccca cagcgttggt aattctggga aaagcagcaa
     6121 aaggatcatg ccaacataga tgacagcagt cgctactttg ccataccact tcgctccact
     6181 taatttgata tttttagata gcccgattaa tccagctaca aacataaagc cttcttttat
     6241 caagaataga ccaaacaaca gccaaagcca cggtcgatac catgccatag acaaaatcag
     6301 aaaaagttgt gtcaatttat ctgcaaacgg atcaagcacc ttccctaagt ctgttacctg
     6361 attatatctc cgagcaatga ccccgtctag ataatcagac aaacctgaga caacaatgac
     6421 cgctcctgct atataaaatg actgtctcag cacaaaataa agataaatcg gcagcaaaaa
     6481 aatacggaat atcgataaaa gattcggaat cgtttgtatt tctttacgcc agtctgtgct
     6541 taatttcatt ttatcgccct acctcctcag cactcttttc tttttatttt agcttacacg
     6601 gggaataaaa ccaatgattt cactgttttt atttttcttt acagccactg atattatgag
     6661 ctaatttgag ataatcactt gctgttttca tcgtttactc ttctttcttc ctgtcgtttg
     6721 cgcatttctt ttactagtac tttatgagct ttttttgatc ctcgctctag gtcacgctgc
     6781 cgtttacgtg ttttataatc gataaacaga ctgtctaaat cgtaacctgt cgggtacaga
     6841 tcttctgctg aacgcaccag acgaacacgc tgacgaggca cgtggattat ttttttgtct
     6901 aaatatacat caatcgtatc ttcacctata tcttcataaa ctaacgcttc tttttggtat
     6961 tcattgacaa atatccgatc accttttgca aagagctggc gttctttttt attctccttc
     7021 ctatttgtaa ctgctgtctt aggaagaaat tcttttttct gtgtccgata ggctttttcc
     7081 gccaagtaac gctctgcttg atggatcaat ttcatcgaca tatccatttt atgagcaatc
     7141 cacaaagctt ggctttctcc tgtttctcca acccgcaact gatatttagg acgaagtgct
     7201 tcccgatcga aagccatagc agccggcaca aaatcttcat gatctccggc gaatttcttg
     7261 atttctccat aatgggtcgt ggcaatgatc aatgcccctt gctcatacat agattccatg
     7321 attgcgatcg ctagtgcagc cccttcattt ggctctgttc cactgccaat ctcatctaaa
     7381 agtaccaacg tattcctttt tatctttttc aaaatagcag cgatgttttg catatgacca
     7441 gaaaatgtac tcaacgcatt ttctaaattt tggtggtcac cgacatcgac gaaaatctca
     7501 tcaaagacag caagctctgt cccttctttt gccggaactt gcataccgaa catcgccatc
     7561 aaagtcaata aaccgactgt cttcaacacg actgttttgc ctccggcatt tgctccggtg
     7621 ataatcaagc ctcgatagtc tttaccgatt tcaacatcca atggtaccgc atgctcaggt
     7681 aaaaatggat gtctgccttg cttgataatg atatgttccg atttattgat tctaggtgtg
     7741 cttccattga tttctcggct aaattttgcc cgagcaaaga tgatatctaa caccgtgatc
     7801 gtttcgatca ataaatcgat cacttcttcg ttttctgcga tagcaccagt caatgccgcc
     7861 aggacttgat attcttcact gatttcttca gcttttaaca actgatagtg ttcattcaat
     7921 ttagaaatca cagttggttc aataaaaacc gtcgttcttt tatttgattc atcgataatc
     7981 gttccatcta ttttattttt atagctggct ttgataggaa tcgtatagta ttcgcctttt
     8041 tgaacaatca ttgcttcttg gatcatttct ttgtttttcg gatgacgcaa gaatttcagt
     8101 aattttgact ggatttcttt ttcgattagt tgtaattgtt tgcgtacttt acgcaaatta
     8161 cgtgacgcgt cgtcactgac tttattattt tttattttct ggtcaatcaa ctcttctaca
     8221 tttatcaaat caggaagatg tttgctataa gcaaacaaca agggtgtctg gtattgattc
     8281 ttatcaaaaa actttgtgat catccgactg cttctaagaa aatccgcata ttcgatcaaa
     8341 tcggttggct gcagaatcaa cccttttttg acttgttctg tcagtgcatc gatcctcggc
     8401 aaccccataa atggaacatg ctgactgctt tctaagatca agcgtgcttc tcttgtttct
     8461 tcttgacgat ccaagacagt ttgtaggttt gtcgagaccg tcatatcgct gattcgtttt
     8521 ttgctatagt ttccaattgc tcttgcttgg atttcctttt tgatccgatc aaattgtaat
     8581 tgactaatca tttcgttgtc catattctct ccttttcttg aagagatacc tgtcccaaaa
     8641 taaataaggg cctagagata aataaaagga tagaacacag cttaaaaaag tcatgtccta
     8701 tccttattag aatacaaaga tattgttttc ctgacaggta ccgtttcata agcacaccaa
     8761 ataaactttg tttattggct attcgactta ctgattagat accagctaca ctcacaaaac
     8821 ataccccatt cttctaggtc ttatttattt tccacttaac tatagcaaga cacattttgg
     8881 ttgtcaaact ttagtatgtt ttatagattt acaccattaa tgaatagaca cctaccgcga
     8941 taattgctcc gatcattgga cctgcgattg gtacccatga atatgcccaa tctgaagttc
     9001 ctttattagc tattggcaat accgcatgtg ctaatcgagg accaaagtcc cgagcagggt
     9061 tgattgcata tcctgttggc cctcctaatg aaagaccgat ggctaagatc aatccaccta
     9121 cagcgaatac gttcgttcca ggtgcaaatt cgttttgtcc aaaagctagc aacccaagaa
     9181 ctaatacaaa tgtaccaatt aattctgtga tcacatttgc tggataattc cgtatagcag
     9241 gacctgttgc aaacgttcct aaaatcgcgc tttcatcttt cgttgcattc caatgtggca
     9301 aataagaaag ccaaacaaga atggcccctg caaaagctcc taaaacttgc gcaatgatga
     9361 aaggaacgac aagattccaa ctaattgccc ctgtcatcgc catagctaga gagactgcag
     9421 gattcaaatg agctgggccc atgaatccag aaatatagac agccattgtt acagcgagtc
     9481 cccaaccaaa tgcgatgaca atccagccag aagcctgtgc tttacttttg tttaaattca
     9541 cagccgcaca cacaccatct ccaagcaaaa ctaggatcag tgtcccaata aactccccca
     9601 tgatttgagt catatcactg ttcatttatt tctccccctt tagttcccgc agatctgatt
     9661 ctgcaatcaa tgcttctaaa cgtttagtct gttgcgcctt ctcctcttct gtccattcaa
     9721 aatatccagc aattgcatcg atcacaggtt gcttgatctc atcaagctga tctcgttcaa
     9781 acaacagatg atttgtacga cgaatgagat aatcgcctgg ggccaaaacc atttcttctt
     9841 ctaaaccata acgtaaccga gctgactcag cgagactcaa accaggataa ggtgccattt
     9901 cttttgctaa ttcaaagata cgtcgggcat tagtcccgta aaaatcagcg atataagtag
     9961 catcttcttc ctctaaaccg gctgctactc cttcttttgc taattctgtc actgtttctt
    10021 ctaatttagt tggatcgaag tttccacctg aaatctgata ttttttagag tcgatttctt
    10081 tcgtctctat tccgtattct tcttttaata attggcgtat caatcgcaaa gctccttctg
    10141 ccatcttacg gtaatcggtg attttcccac cagataaagt cagcaaacca tctggttctc
    10201 tttctaaaga actacctctg gaaatcgtag aaggtgcttt ttcatcacgg ctgttttcca
    10261 aatggttcaa cacgtcttct acttcagcac gagaaacttt gttttcctta tattcactta
    10321 ctgtatcgac aactttattg aagctcttgt ctgaaatcga tccattatct ccaccattgt
    10381 aatcagaacc agaattacca atcaacagtg gacgaagtcc tgcccagctt gcttcgatat
    10441 cattcaatgt gatatttgct tctggatagc gatgattgat cacatccaat agataatcta
    10501 catcttcttg tgtgactttc ggatccgtaa aatctccttg gtaatccgta tctgtcgtac
    10561 caaagtaagt cttgttttct cttggaatag caaaaaccat ccgcccatct tgctttcctg
    10621 tatcgaagta tgtgggttgc ggtacaggca gttttttcgc atctacaact aaatggatcc
    10681 ctttagttgg acgcatttta ggagagactg gacgcgtaaa attcaagttt cgtactttat
    10741 ctacccaagg accactcgta ttgatcacta attttgcttt gatttcgatc acttcatctg
    10801 tcagcaggtc acgagctttg acgccaacga tttgatcgcc atcatataaa aagccaaccg
    10861 ctttcatttt acttactaga taagccccat cttcggcagc ctttttgata ttatcaatca
    10921 ctaaacgggc atcattgttg cggaaatcta gatagacacc cgcgcctttt agcccttctt
    10981 ttttcaaaaa cggttctctt tccaatactt cttctggtgt cagcgtataa ttctcatatt
    11041 tggttcctgt cacatttgcc agtttgtcat aaaggtccat tgctactttg accgagaaca
    11101 tattgaaggt tgttgctcct tcgccctcat agattggcaa aagcattgga tctggttttg
    11161 ggatgtgtgg ggcaatactt tgtacgactg cacgttcacc aactgtgtca gctactactt
    11221 ccacatcaaa tgtcttcaga taacgaatac cgccatgaac aagtttggtc gagcgagagg
    11281 aagtcccttc tgcaaaatcc tgcatttcga tcaatcctgt tttgattcct gatgctgctg
    11341 actggactgc cacaccggca ccagtgattc cgccaccgat gatcaacaga tccaattctt
    11401 cttgctgcat tttttgaatg ctatcttgtc ttgtcttgtt tgaaaacata tggatttcct
    11461 ccttattcaa atgcttgggt agcttttact gcttttttcc aaccgttgta aagtttttct
    11521 cggcgctctt cctccatttg aacttcaaat agcttgccag cttcataaaa ttcgcggatc
    11581 tcgtctgtat ctttccaata accgacagct aatcctgcta aaaatgctgc ccctagcgcc
    11641 gttgtttcca agttttctgc tcgttggatc ggtacattca agatatctgt ttggaattgc
    11701 atcagatatt cattgtttgc tgcaccgcca tctactttca atacaggaat cttgattcca
    11761 gtgtcatctt gcatcgtatc gatgatatct ctcacttgat aagcaatcga ctgtaaagta
    11821 gctttaatga tatcttcttt tgtcgtacca cgtgtcaagc caaacatagc ccctcgtgct
    11881 gcctgatccc aataaggagc acctagccca acgaatgcag gaacaacata aacctcatct
    11941 tcgcttgtag agcgtttcgc tgcgtcttct gaatcgctag ctttttgcaa catttgaagt
    12001 ccatctctca gccattgaat cgaagaacca gccacaaaaa tacttccttc taaagcatag
    12061 taaacctttc catttatgcc gtaaccaatt gtcgtcaata aattattttt ggataattgc
    12121 ggtttttcac cggtattcat gacaataaat gaacctgtac cataagtatt cttgaccatg
    12181 cctggttcga atgccatttg tccgaataat gcggcttgct ggtctcctgc catccctgaa
    12241 attggtgctt cgcttccata aaaatgataa ccttgcgtat aaccataaac ttctgagtta
    12301 gaagtgactt ttggtaacat cactcgagga atatttagta aatctaaaat ctcctgatcc
    12361 caatctagct gatggatatt gaacaacatc gtccgactgg cattcgagta atcagtaaca
    12421 tgtgcttgtc catcggtcag tttccatact aaccaagaat cgatcgttcc aaacatcaat
    12481 tcgccttttt cagctcgttc ttgcgcgcct tctacatgat caagaatcca gcgtatcttc
    12541 gttgctgaga aataggcatc gatcactaac cctgtttttt cgtggaaaaa ttcttgatag
    12601 ccttcatttt ttaagttatc tgcaattcca gctgactgtc tggattgcca aacaactgca
    12661 tgatagattg gacgtcctgt atctttttcc catattactg ttgtttcacg ctggttcgtt
    12721 atgccaatcc cagcaatctg atttggtttg atccctgatt cgatgaacgc tccggcaata
    12781 actgactgta cagaattcca gatttcattt gcatcatgtt ccacccaact ttcttgcggg
    12841 aaatattgcg tgaactcttt ttgagaactg ccgatgtgtc ttcctttctt gtcaaagata
    12901 attgctcgtg agctagttgt accttggtca atcgccatga tatacgttga ttctgtcatt
    12961 gtgattccct ccattatatg caaacgcttt ctttaactac tcttatcata ctactgtttt
    13021 aaaaaaagaa actgtcaaaa ttttattctt tttttctttt tttgacagtt ttttattatg
    13081 aagctatttt ttaatcaatt cttttctttt ttcagcgtct ctattcttct tttcaatcga
    13141 ataatgtcgt aaggtgacgc aaattctgac agataatatt cacactgttt tttgtttctc
    13201 tggcaaaatg tgatcaccaa atcatattct ttaccttctt cataacttcc aatctcaata
    13261 ccgccgattc ccctcagttc tctgatcaga tattgttgaa aagcaatacg ataaatcggc
    13321 agactttcta aatcgattcc aatcactact ggttttgcaa tataaaaatc gatcatcaaa
    13381 agaacattgg catactggat catcaggtaa ctaagctcac tatcttcagc tcttttcctc
    13441 ggcaattgct gcaccgctgt ttcctgtaat ttcgccagta actgtgttaa ggaatgcccg
    13501 agcattttct gctgctgttc caaaagccga tcacgctcat agacttcgat ctttccaaca
    13561 aagaaaaacc attcattgtt gatctgggaa atttggtagc ctactgcctt ttcttctttg
    13621 attttcaaac gacgaggacg ataatgccat aacatcgttt cccgaatgta agtatctaaa
    13681 acagcggttg gtaacttttt gctccgtgtc aaatcatact gataaaatat ttcttcgtct
    13741 actatcgaaa aagaaacaaa aaagctgtaa aacatcattg tttcgtatac attcagttct
    13801 gctgctgttc gactaagatg catcacgatg attggatcga ttgcttgata aagccggtcc
    13861 gactgataga gtaatttctt ttctttcaaa gttgcgtacg tacttttttc attcaatagt
    13921 ctttttttcg taatcccgag ccagcaagca atctgtgctt ctgctgatgc cgtaaacgtt
    13981 gtttctaata cacggtccaa tcctagaatg aacggtcttt tttctggtgt attttgcaaa
    14041 aaaagcggtc gctgatcttc cgggatatat tggaatagtt cataataaaa atatcgtatc
    14101 tgtagctctt ctccgtataa ttgaccgttt ttgatttgta atccaaattc ctctaagagc
    14161 tggttcaatt ctttgatctt tcgaaaaaca gaagactcac tgatattaaa cgctgtcgct
    14221 aatcgaacga tggatacttg ctgatgttct aataaataga cgagcatctt aaacttcaag
    14281 ctttcctgca ataaaaacaa tagaattttt tccaaactta catcttcgtc caacacaagc
    14341 agcgcctgat actcatttcg ctgtacttct actttttttt ccatcattcg gccaatcaat
    14401 tcaatatctt ccaaatattg atcaaacgag gcttttgaca gttggacatg ctctctcaaa
    14461 ccattgatag aggctgttcc cccttgcaga acaaggtttc gcaaaatcag gatctgtaac
    14521 tgctcttttc tttctaataa tgcttcaatc ttcataggca gtattcgcca cctttgacca
    14581 caccatatct ggcacacggt attctggctg gaaaaatagc tcatgttctt ctaactgttc
    14641 aaacgtccat ccttctttta ctgcaattgt cagttggtca agaaggtgga acatctcttt
    14701 tttgctttgg agctgtgctc caagaatctt tttttcagaa tcaaatagaa atttgagttt
    14761 aactttgctt tgatttattg ctgtaagctt gtagtctacg tatcctgttt caattttttg
    14821 gggataaaaa atgctctctt cttctgtcaa acctacgctt cctaagaaat agccaaacca
    14881 ctgattgccg actggacgat aggttccctg atcctttgtc tgtgagccac taattgtctt
    14941 gctgacattt cgtgctgtac ggacagcgtt atttactaga gaaacataca ttttttcatt
    15001 tgttggacga aaagttactt ggatcgcatc gccaatcgca taaacgtctt tttgagacgt
    15061 ttgcaagtag tcatctaccc agatcgttcc atcatcattc aatgttaatt gttcttccca
    15121 catctgattg tcggggcgag aatgattagc cagcaaaaca agatcatagt tctcctttct
    15181 tttttccgtc tctacaatag cggtttcatt ttcggtcaaa gacacaactt gttcttctaa
    15241 aaaaagtgaa agcccttgat ttttcatttc ctttactaac ggttctgtca tttcaggatc
    15301 tagataacga aaaagaattg actttcggct ttcgtaaaga tggatttgtt tttttcttga
    15361 tgccaaccct tcagctattt cgattcctgc ttgtcctgca ccaataattg caattttctt
    15421 tgcattcatg atcttttgct gaagagccgt tacgttttgt atctttttaa ctgggtgaat
    15481 aagcgttgat tctgcagaaa tatttcgaaa cttttgattt gaaccagtcg ctagaatcaa
    15541 acgatcaaaa tccaattttt ttcctcctgc taaaacgact tttttttctt tcaatcctat
    15601 tactgtcttt tctgtgtaaa catggattcg atagcggtca gtcagttctt ctttcgtgat
    15661 ccaagaaagt tgtttttcac tggtaacctt tccttttaat atcaaattga acccgctggg
    15721 aatccatcct aacttcgatt gcttttcaat caaatatatt tcacttgttg gcatcaattg
    15781 gcgaagataa atagccgcat gaatccctgc aaacgacccg ccgacaatta caatgttcat
    15841 ctgcattcct ctttcttata aggtgttcta ctgctaactt ctcaatcaga aaacacagta
    15901 ttcataactc gctttcaacc ttatgataca tagcgatgca gcagaatcaa ccctctccat
    15961 cataccgtgt tctaggtctg cttctcaata atgtactagt ggacctaatt gaagagtatc
    16021 atttctgaag agatgtttca aaaaatgtac tcttataaaa gaaaaaaact cgccttttac
    16081 gtacctctgt ccaaatagga aacagaaaag aacgaaaaga cgagttttag cgtgtgtaat
    16141 gtaatagtta gaatagacac atcatttatt tttaattctt taatgcttca acaactgctt
    16201 cgcctaattg atgagcagat tgaggatttt gccctgtaag aagccgccca tcaatttgaa
    16261 ccacttctga aaaagctgct ccagactgat agtttgctcc tttttctttc aaagcatctt
    16321 ctgctaagaa tggtacttca ttcgttgtac catttgcttc ctcttcttca ttactgaacc
    16381 cagtcactgt acgtccagct aaaatagatt ttccagactc atctgtaact ggcaacaatc
    16441 ctacaacacc gtgacaaaca gctgagacca gcccttcatt tcgatagatt tgtgaagcga
    16501 ctttcccaag atctattgct tctggaaaat cccacattgt tccgtggcca ccagcataat
    16561 aaaccgctgc ataatcattt gcatccacat catcaggacg taaggtattt cccaaggccc
    16621 gatttctgaa atcttcatct tcataatagg cccaatcgat ttcatccata ttcaaaacac
    16681 tttgcggttc taaaggtaca tatccgcctt taggactgac aaaatctgca tcgatcccat
    16741 tttttactaa tacatcataa aaatgagtca gttcacttaa ccacaaacct gtaggacgct
    16801 cgatcttttc gtacttttct acatttgtta atacgatcaa tactttcatt ttcccatcct
    16861 ctttctataa aaattgcgtt attgataacg tgctttcaag aaattatata atgggcttgg
    16921 caaataaagc tctttatatg cttcttcaaa aggtttcgtt acaaattcat cctcacggtt
    16981 ttccaataat ttctctgccc agtcaggatc gacgatcatt tgctgtccaa ttgctgcaag
    17041 ttctgcatat ttcaatacct gctctacatc ttcgcgattg cggatcccac cgacaccaac
    17101 taaagggatc tttccttgaa tcgtgttatg gaccacttca agaatcgatt tatcgttgta
    17161 tttatcagaa cgagctattc gatcatacat atttaatgaa acatgcagat aatctagttt
    17221 tgactcacgt aatcgttcaa gaagccagat cgtgtcttca aaacggatac ctggtgtttc
    17281 atattcttct ggtgagaaac gataccctac gatgaatggt tttttagcat attgttcaac
    17341 cgctgagaaa accgttgtta ataattcttc aataaaacga taacgatttt ccaagctacc
    17401 gccccattga tcctctcgtc tattcgaatg cggagagaaa aattgttgga tcaaatacgt
    17461 atttgctcca tgcaactcga ttccatcaaa tcctgattca atcgctctac gtgtggcttt
    17521 gccaaatgct tggattgttt caacgatttc ttcttcactc attgctcgtg gtgtttccgc
    17581 atcaggacgt tttgctgcaa ctgcacttgc agatacaggc tgttctccag ataaagttgc
    17641 tcgacttgtc attcgtccac cgtggaaaat ctgaataatc gcttttgcgc cttctccttg
    17701 gattgctttc gctagctcac ttaatcgagg aatcatttca tcatgagcga tgctgagttc
    17761 acctggccag ccttttccga tatcttggac atttgcagca ccagtaataa cagcaccaag
    17821 acctttagaa cgttgtttat aataagtgat ctcatcttcg gtgatcactc cattgaaaaa
    17881 gctgagttgt gtcgtcatag gcgacagcat caatcggttc ttcaattgaa ctcctgaagg
    17941 taaagtaatt gattgatcaa attgtgacat tgtcattcct cccataattc gctctgatta
    18001 acctatcgag aatcatctat cattaaacca ctcgattagt tgtacatgca actaatttgc
    18061 ttaaaaaatt ttattttttt tgtaacttat ctgttgcatc attcattgtc tgggctaatt
    18121 ctttacttgc ttcatttccc aaaactgctt tgtatgactg atgaagttct tcccagctac
    18181 catcgacttc cttagcaaat tggcgtcctt gttctgtaag ataaactaat gacaagcgac
    18241 cttcgctaac tgttttgacg tatcctttat attctaattt ttcaacaaaa cgagcaatcg
    18301 ttgatggggc ggaatagagc atttgtgcaa tatctttttg tggtattcca tctttttctt
    18361 ttaatatcaa taaaataaaa ccataagttg gtgccagacc tgtccttcta aacgcttcat
    18421 cagctaattt attcaacatg cgatctagct ttttcacgct aaagaaaaga cattcatcta
    18481 acgctttttc aattggcttt tccatttcat cccctccatt ggcgtacata tcatagtatg
    18541 atttttattt tttgtcaaaa aacacggaat aatgtccgcc tcctctgtct agatttgaaa
    18601 aaaagaagta gccatcttca aagaatttcg gcttgttttc gacaaaactc cttctggaac
    18661 accgtgaatc agaggttgtg aaaaagtcgt ttagttttga gtatgaagaa aaattttgtg
    18721 aaaatggctt tccacatttt tgcataaatt tggcttaata ccgaaaaact ggcttttgaa
    18781 caccgtttat atcagaggtt gtgaaaaagc cgtcctgcat caagtaataa gaacagccaa
    18841 acaaaaatag ttcctcatat tttgtcgttt tttgagctaa tgccgatggt cagctgattg
    18901 tacaccgttt attgagaggt cgtgagcctg ccgttgaact ccgagtcaca aggagcaatt
    18961 tcaaaaaaca gcttctcatg ttttatgact atggtgactt gtgatcgagg agttggcagg
    19021 agaatactgt ttattcgtaa agaaggggct gtgacaagac ttttgtcaca gtcccttatt
    19081 tccttttatt ataggatttc gccatttgat tggatgactt gtctgtacca atcaaatgat
    19141 tttttcttta accgtttctt tgtgccattc ccttcgtcat cttgatcaac atagatatat
    19201 ccataacgtt ttgacatttg tgaagtagaa gcgctgacga tatcaatgca gccccacgac
    19261 gtataaccaa ataaatctac tccatcttcg atagcttcct tcatctgctc aatatgctgc
    19321 ttcaaatagt caatgcggta atcgtcttga acggttccat cttcttctac tttgtctata
    19381 gctccgagtc cgttttcagc tatgaacagt ggtttttgat acctatcata taattgattc
    19441 aaagcaattc tcaaaccctt aggatcaatc tgccagcccc attcacttga tggaagatac
    19501 ggatttttaa ttcctccagt tattaagttt ccttggaccc cttccaaatt ttctggatga
    19561 gcactgactg cactagacat gtagtagcta aaagaaacaa aatcaacagg gtaggctgct
    19621 aagatttctt catcacctac ttctattttt aagttgacac ctttttcttc aaacattcgt
    19681 tgcgtatacg ctggataata tcctcttgct tgaacatcac taaagaacaa agaagttctt
    19741 tgctgctcaa ttgttttttg aatatcatcc ggatcacaag aatacggaac aagaagctga
    19801 tagctgatca tacaaccgac ttgtgaacct ttgataattt catgacaagc ttttgtagct
    19861 aaagcacttg ctataaactg atggtgtgca ccttggtatt tcgcttgttc caaatgggga
    19921 tggttttctt caattactcc tacgctaaca aaagggtgat gttttacaca gttgatctca
    19981 ttgaaagtca tccaatattt tactttattt ttatagcgtt tgaatactgt ttcagcgaaa
    20041 cgaacgtaaa actgaataag ctttcgatta ggccatccac catattctgt aaccaaatat
    20101 aacggcattt cataatggga aagagaaacg actggctcaa tcccatattt tagacattcg
    20161 tcaaacactt gatcataaaa aaataatccc gcttcattgg gtgtttcttc atcaccatga
    20221 ggaaaaattc ttgtccatgc gatagacatc cgatagcatt taaaacccat ttcagcaaat
    20281 aaacggatgt cttctttaaa gtgatgatag aaatcatttc cgtgtctttt aggataataa
    20341 tacttgctgt tgggatcctg cgccgctttt acttgctgat gcgtcatcat atgccattga
    20401 tctgtccatt tttctttagg taaatcgctg tcgaatgtat acacatcaga cacagataat
    20461 cctttttcat ctacatccca tgcaccttca cattgattgg ccgctgtcgc tccgccccat
    20521 aaaaatcctt ctggaaattt tttcatatcg atccccctaa acttgctagt tttcttgttt
    20581 gattattttt cttatgacta gtaatgatat ttttgaatct actactattt gtaacaataa
    20641 ccattgtggt cggatcatat ccctctttga ttaattcttg caaatctact tccatcaata
    20701 aatcgccttt acgtactttt tttccatcag atactgcact ttgaaagtat ttgccattta
    20761 aattcactgt atcaataccg atatggatca gtatctctgc tccttcttca ctgactaccc
    20821 caattgcatg tttcgttgga aaaactgttg aaacttcccc gtttacagga ctgtagattt
    20881 ttccgtccgt tggaatgatc gcaaaccctt ctcctaaaga tccactagca aatgttggat
    20941 cgtttacttc agataaatca attatttcac ctgctgcagg agtacttaac actatatcct
    21001 ttgaggattc ttcttcgatt tcatccttgt agccgaaaag aaaagttagc atacaggaac
    21061 tgatcatcgc taagaaataa ctagcaacta gccaaacaaa tccttcacca atataaatcg
    21121 ggaaagacaa aatacttctt gtagcaactg ccaaagcacc ggctcctgcg gcaccagcta
    21181 ctccaccaaa tatagctcca catatacaag caatgtaaaa tggtcgttta tatttaagag
    21241 tcacaccata aacagcaggt tcagtgattc caaataatgc tgtgataaat gcagataaag
    21301 ataaactttt tactttctta tttttcgttt tcaaaaatac cccaagtact gctcctgctt
    21361 gcgcagctac ggcagtcata catgctggac ctagcgtatc acgaccgtag aaagaaagat
    21421 tgttggtcat tactggtaca agtccccaat gtaacccaaa aatcactaac acttgccaaa
    21481 atccgccgat aacagcacca gataaaacag ggctaaagtt ataaacagct aaatatccag
    21541 ctgcaatcag ctgacttgca taatctgcaa ttggacctac aactaataaa gtaattggga
    21601 ccatcacgat gatacaaatg aatggtgtca ataaatttcg aatactttcg tgcaagcttt
    21661 tgcgaatctt aggctcaata taagaaagaa cccatacagc taaaattgct ggaataaccg
    21721 tacttgtata tcttgctaga atcacgggca tccctagaaa tcgcaaggtt atgctatcac
    21781 tatatgcact gacaatcgta ggataaacga gagctgctgc aataaccata gcgatgaaac
    21841 gatctgtatt gaactttttt gcagcagtat atgccaaaaa tataggcaag aaatagaaaa
    21901 atgcatcagc tgctgcattc aaaatgatat aagttcctga ttcagtagtt aataaattca
    21961 aactcgtaca taaggcgagt actcctttga tcaaaccact tcctgccaag acgcctaaag
    22021 tcggggcaaa aacagcggcg atcatgtcta taaaagagtt taaaatgcct tttttctcag
    22081 ttcctctctt tccactagat gcatcatctt ctagtttcat ttgtttggat aatacgtcat
    22141 acacttcatt tactgcattt cctactacga cttgaaacat tcctccagct tcgactacag
    22201 tgatcacacc ttctagttgc tctaccttct ccttatctgc cttcttatta tcttttaggg
    22261 taaagcgtaa ccttgttgca caatggtaaa cattgctgac attttcttcg cctccgacaa
    22321 atcggacaat atctttcgct aattgtgaat agtccatttt tacttccccc ttgttaatta
    22381 atgccgtagc aatccttctt acaagataag tatagttctt agaaaacggt ttctccattc
    22441 aattagtacc ccttctaata gcgaacgaaa ctgtacaata gtgtgtatgg tttacttagc
    22501 cgagcaaatc actcactgct tgaaagaaaa caagtatatc gtttctctta tagtcaaagg
    22561 agacaaaaaa aacacgcttg atcttccttt gctgatgtat aagtggtatc tcaagctgat
    22621 actctgtgat ttttgtttct acttggcttt tgataagaca gcacaacaaa gtctcggcat
    22681 ttaacggaag cataactagg tcagaactag gagagattag ttgctgaatg gaatctatct
    22741 ttttatggat ttttatttga ttttcttctt tgtagtaatg atcaagcagt tttgttttct
    22801 ttttttcttc aactatggtc agcttttcac gcaaaatctg ataaatctcc gaagattcaa
    22861 actcatctag aacactaggt agataaatca aatcatccca ctcaaaaata agctcttgct
    22921 cagtagtcaa aattgcatca tattccgtta ttttgtttga ttgatttttg aaaagataca
    22981 ctggttctat ccggcattct ttgatccaca tgttcatact ttgttgaatc tgttttttta
    23041 gtgtattcaa aatactaatt ggctggttac taacaatcag tatctcccct tgttttcgaa
    23101 aaggattcaa cgcttcggca agatacaaaa ccaaataagc gctttcagct aaattgggac
    23161 gtaattgaaa atgtattggg aagaaacgcc gaattaaata aatttctaaa ggataacggg
    23221 agatgatctt ttgtacaaaa tgattcatgg tattatgtcc ggcatccatc ctcgttttca
    23281 tttgtttgat atgggttagc aaaaattctg tttcatggaa caataacgaa acaggaagat
    23341 ctaaaaaacg aataatcgtt tgctcaaatg ctcttagatt cttctctatt tctttgtttt
    23401 tttcatcatt aatcatcaaa taatttaact ctaatagtcg attttcaatt gcttgttttt
    23461 cttgattgga aaaagaatag ggtagttctg atgataactt ttttgtgagg gtctctacca
    23521 tcggaataaa taatgtatac ctgtttgttt tttctaaaag ttcttctctt cgaagaatgg
    23581 tcaaaacgag ataccgagaa aatcgtatga agtcctctcc tgaaacaata taattatatg
    23641 atataagaac ctcttttaat gtcttttgga cagtcggcat gatattggaa aaaattgtac
    23701 tgatttgttg aggcaacctt gcgtgttgga tcaccgtttc tgttccaaca agagataaga
    23761 aaattctttt tgaattttct tcagcaatga tttttagtcc ttttgtcgac gaaacttcca
    23821 gttctaattt aggattgcgc tcgatccaac gcaaaatcgt ttttatttgt aatgatacgg
    23881 ctgtttttga aagaaagaaa atgtctgcta tcttttgcat actgacatac cctttttgaa
    23941 acaataagta cgtcacaata gttgaagctc ggaaatccat gctggaatag attttatgtt
    24001 tcgtcacctc ttgtatgatt tgctgtttag tttcagattc aattgattct aaaaaataac
    24061 ctgaacgttt atttgactgg ataatgattt tcttctcgta gatagcaagc atatttttga
    24121 tttcagtttg gatcgttttc ttgttggtac ctaaagcttc agctaattct tcgcttgtta
    24181 tccaatgatt cttatttctt aatactacaa gaatttggag ttgtcgttta tttaagtcca
    24241 tttgcttaca cctcctcttt gttataaaca tacaggaaaa acctctcaaa tgacaatagt
    24301 cacttgcaga ggtttaaaaa tcatttgaag aaagatctat attcaaggtt tttaccatta
    24361 gactggataa tttgtttata atattcaaaa ctatcttttt tcaatctcct aaagcttccg
    24421 ctcccatcat tttgtctatc cacataaata aagccatatc gcttcctcat ttcccctgtt
    24481 cctgccgata cgatatcgat tggtccccac cataagtaac caatgatttg gcaaccatct
    24541 tttattgcct cagcaatttc ctgaagatgt atttttagat actcacaacg ttttggatcg
    24601 tggattcgat tcaattcatc tggtgcttca tctagtccaa tgccattttc aactatgaat
    24661 aatggtaatt cataacggtc tgtcaattca ttcatgacat aacgaaaccc tagaggatca
    24721 attggccaac tccaaggttc gggagatttt tccttcaaaa agggattatc gaaaccattt
    24781 gctccgccag tatctacgcg catttctgct tcttttttat agacagcgct acgataataa
    24841 ctaaatgcaa tataatctac cgtgttagct tgcaagtact gttcgtctcc atctaacatt
    24901 actggtgcac agtcttcttc cttccatatc ctgtaaatat aagctggata atgccctcgg
    24961 cacatgacat cggagaaaaa ccatgaattg cgtttaaatt gcagtgaacc aaatacattc
    25021 tctggatcac agtcatatgc ataagtcgct aatgcagaaa agctacacat aatacccatc
    25081 ttagcatttg gatcgatttt ctttaataat tgagtagcac gggcgttcgc tagaaacata
    25141 tgatgacagg cttgataaat ctcttttttt gttagtgtag caatgggttc aagtttatct
    25201 ctagcaggga atgtaaccaa tccagcagct gcataaggca tacgaaaagc attattgatc
    25261 tcattaaagg tcatccaata tttcactttc ccttggtagc gttcaaagac ggtctgcgca
    25321 taaaattcaa aaaagtcgat taattttcga ttttgccacc ccccatactc tcctaccaat
    25381 gctaaggggg tttcataatg actaagagta attactggct cgatatcata tcgatttaat
    25441 gtattgatta gtctgtcata aaatacgaga ccagcctcat ttggcttctg ttcgtctcct
    25501 cttggaaata ttcgtgccca tgagatgctt gttcgaaaag cttttaaacc taactccttc
    25561 agtaaacgaa tatcctcttc aaatcgatga taaaaatcaa tcgcttcatg agaaagataa
    25621 tggagtgatt cgtctaaagc aatctcccaa atcttttttt cttcattcca ctgaatacta
    25681 ggatgctggt tcatgatccc gataagcgta tctgtcacat taggtaattt gccgtcttcc
    25741 aaccatgcac cttcacattg attagcagct actgctccgc cccataaaaa attttctgga
    25801 aatatttcct gatccataac tatctctcct cgctatcaac aatttcttac ttgaagtata
    25861 gctcgattca tcaaaacaag atattctaac tatttcggca gaagagaaga aaaaaattga
    25921 atgctactct tcatttttaa tatttatata taacaaatac ataagacgat ccccgaaaga
    25981 aaacactcgt taaccatcta agcaaacgat ttattttact tccaacacaa atgcttcata
    26041 aggtcgtaaa tcaactttgc cgtctggtaa ctgtttcaga ggataatttg acacaataac
    26101 ccttaaagct tcacgtggaa cagtgaacgt ctgcttttca ctggacatat tacaaataac
    26161 gagccattgc tggtcttcat atatgcgaga ataggcaaag acatgctcag gcgtcttttc
    26221 cactaattca tagtctcccc agacgatgat gtcatgtttt ctacgcaaat cgatcaattt
    26281 cttgtacata taaaaaacag aatcttgatc tgctaacgct tcttctgcat tgatttcttt
    26341 ataatttgga ttgactcgaa gccatggaat tccagtagta aacccagcat gttcacgggc
    26401 gttccattgc ataggcgtcc tagcattgtc tcttcctttc gcattgattg attccaagat
    26461 ttcctctttt gtaaatccag aagaaatcct ttcgttatac atattgattg tctcaatatc
    26521 ttttgcttcc gcgatatcat cgattgggca attcgtcatg cctaactctt ctccttgata
    26581 gatataaggg gtgcctttca tcatatggag caagatagca aacatcttgg cactttcttt
    26641 tcgatacaca tcgtcatttc cccaacgaga aacaattcgc ggaagatcgt gattattcca
    26701 aaataaacta ttccatcctt catcacctaa agatgtttgc catttggata atactttttt
    26761 cagttcagag atactcaagg gtttcaaatc ccatttgtct ttgccttctt gctgatctaa
    26821 tcctatgtgt tcgaattgga agaccatgga taattcattt cttttaggat tggaataaag
    26881 tttagcgatt tcggtagttg ctccccatgt ttcgccaaca gtcatcagat ttttgtcacc
    26941 aaaagttgct tgattcattt cctgaagata ctcatgcagt ttaggtccat tacttgtgat
    27001 ttctttatcc ggttctttgc caatcatatc gatcacgtcc atacgaaagc caccaatacc
    27061 tttatcgatc cagaaattca tcatttgata aatctcttgg cgaacctgtt tatttttcca
    27121 attcaaatca ggttgacgct tgctatacaa gtgcagaaaa tattgccccg ttttttcatc
    27181 caactgccaa gcagaaccac tgaatattga gcgcaatcta ttaggctctt ttccattgac
    27241 cggatcacgc caaatataat agtcccgata aggattttct ttatttttac gggcctcaat
    27301 gaaccacgga tgttcatcag aagtatgatt caccaccaga tccatgatga tacggatatt
    27361 tcttttcttt gcttcttcaa tcagttcttc catttcttcc atcgtaccga attctgccat
    27421 gattgcttga taattactga tatcataccc attgtcatca ttcggagact cgtatactgg
    27481 agaaagccaa attgcatcaa tacctaaata cgccagataa tccaacctgg aaataatccc
    27541 ccgcaaatct ccaataccat cttgatttga atcttgaaaa cttcttggat agatttgata
    27601 aacaactgaa tggtgccacc atttttgttc catgattttc ctcctataaa tggatgtttc
    27661 tattttttgc ttaatcattt attttagtct ctctcactaa aaattgtaac gctttcaaat
    27721 agctattgca ccttgttatc ggtaacagaa taaaacaaaa aaacagctga ggaaattccc
    27781 tcaactgttt tttgaaagga ttgatttatt cagggaagaa tgctgatttc acaacttctt
    27841 tataaacggt gttcactcag ctgtccctcg gtattagctc aaaaaacggc aaaatataag
    27901 aaactatttt tttcgttttt ttctctaata ctcaggccag aacactgatt tcacaacctc
    27961 tttataaacg gtgttcactc agctgtccct tggtattagc tcaaaaaaag gcaaaatatg
    28021 aggaactatt ttttcgtttt tttctctaat actcaggcca gaacactgat ttcacaacct
    28081 ctttatttca cattcaatat ccacatgaat cccatgaata caaagaacag accatacatg
    28141 atgggagata cttcttttcc tcttttagct gctaacatgg taattggata gaagataaaa
    28201 cctaatgcaa tcccatctga aatactataa gtcaaaggca tgccgatcaa gatcaagaat
    28261 gaagggatcg caatctctaa gtttccccat tcgatttgtc gcaaagattg tgccatcaat
    28321 actcctacca taatcaatgc tggtgcagtt acttgtgaag taacaactga tagtaatgga
    28381 gaaaagaaca agcctaacaa gaagaaaatc cctgtagtaa tagctgtgat acctgaacgt
    28441 cctccaacgg cgataccagc tgatgattct acaaatgcac caacaggaga agtacctaat
    28501 aaggaacccg caagcatagc tgttgaatca gaagctaaag ctttccctac acgaggcatc
    28561 ttgttgtctt tcatgaaacc tgcttggttt gctaatccaa ctaaagttcc tgctgtatca
    28621 aagaaagtca caagcaagaa tgtcagcact acgacccaca tttgaagaga attgatgtcc
    28681 cctacatgtt ttaatgcaac taaaaatgtt ggtttcaaac ttggtgctgc ggcaacaatt
    28741 tcagaaggca ttggaatcaa acctgtgacc agacctaaaa tcgttgtagc tgccatcccg
    28801 atgaagatgc cacctggtac acgccgaaca agcaagatag cagttacgac taatccaaaa
    28861 atcgtcaacc aagtagaacc aacgttgagt gatcctaatc ctactaatgt agattcattc
    28921 gaaacgatga tcccaccttc gctcagacca aggaaagcaa taaatagacc gataccgcca
    28981 gaaatcgcat atttcaaatc tgctgggatc gcatcaatga tcatttcccg cagcttgaag
    29041 attgtgatca aaataaaaat caaagaagca acgaatacgc cggctaatgc tgtttcccat
    29101 ggaatcccca ttcctaaaca aacagaataa gcaaaaaaag cattgatccc aagagcaggt
    29161 gccgttccaa ttggataacg ggctaatacc cccattaaaa tacagccgat cgcactggct
    29221 aatgcagtcg cagtaaacac tgctccttca tccattccag aagcacctaa tacagttgga
    29281 tttacaaata agatataagc cattgagata aatgttgtaa atcctgccag tacctcacgt
    29341 tttaccgtgg tgttcaattt ttctatttcg aagtaggaaa gtattttttc cttcatcttc
    29401 catcccccta aatccgaaca ttataaataa agtccgttaa aatttcgatt tattaataaa
    29461 acaacgtgtt ttatcatata ctaaaacaaa acataagtaa acaaaaaatt cggattttaa
    29521 gcaaaatccg aacgttccat ctgattaaat ccctttatct caaagttcat gaacattcac
    29581 tttggattac aagaatttct ttattgtgtt aataaagttt cttcattcta gtctcaaaaa
    29641 tcaatagtgt gatttgattt taccatttcg tttctgttct tctttgatga attcttttgt
    29701 atcgacagga ttcagattat ttagtccgcc aaaacctgta tcgaccattt ttccccagcc
    29761 ttttgtcttc ttttttcctg atttgagatt ctttgctcga agcttctcac tatgttttgc
    29821 tcgccgatac ttcaaataac cttctaatct tcccattaga tccactgttt ctcctccttt
    29881 ttattcaatc agacgactca gcttttccta taacaaaata attgccttca gggtccgaaa
    29941 aattgaaagt caagacgcca ttgttgtctg tgatttctcc tggttcttcc atgttctcgt
    30001 agatagtttc aaattcatcc gtaaaaaata ctaaagaagg cggtggtcct aatacctctg
    30061 gtgaaaactt ctgcacaaat acttttggga atacgcctaa ttctaattct tttgagatgc
    30121 tgagtacaat actcttaaat tcttctggca attcgattgt ttcagaaatt tctgcaccaa
    30181 ttttttctac aaagaatcgg caaatcatct ctacgtcatt gacataaagc atcacacgtg
    30241 ttttttgtat catcgtttga cccttctttc tatttgattt tctttcctgt ctataaactg
    30301 attccattat atcacgaaag cgcaaacacc ttgtgtttga tactattcaa gaaaaataaa
    30361 gcaatagttt ctaggattgc tttcctccac aaactttttt tacaaaaaaa aaacggcaat
    30421 gaatgccgct cttcttattt cgattctttt ataattctgc ttctgattca tctttggtta
    30481 gtgtgtgtct aacactagtt acgccaaatg tttgatcgat tttttccttc aacgcttcga
    30541 ttgcctgtgc gccacgtgcc gcttgttcag cattgatgga ttcaatgacc agcaccgctg
    30601 cttgtgtttc ttccgtcagc atcgttcttt gggcttcacg ccagttgaga cagcgacaga
    30661 tcgctccttg ttcatcatag tagatgattt cttccggaag tgccggagca tcggaatctg
    30721 cacctaaagg caggaatgat tcgtcacctt gggcttttcc taaatgcaga tttcctgcga
    30781 tcttttcgat atcttctccg ccgcaaggta cgccaaaaga caaggaaata ctattataga
    30841 tatctacaag cggattgatt gggaaaaatt cccgttcttg atttgcacgt ttcagtaaag
    30901 cttcaataga agaacgtgca ccttttttag tcttgaatgt ggtaaatgcc tgacgccact
    30961 gagcaatgac ttcgttttgg ctgaatgttt cttctgtaag gtaatttctt gcttcttttg
    31021 ctgcctcatt caataattga tgatacgttt cttcactttc ttttgttacg tggttatcga
    31081 taccatttac ggataagatt tcgatggttg cttcaggaaa tacttcccag aaattggtat
    31141 ccactattac ttttttcatc tgttcacacc tcttgattag aataattgct tgatgaatag
    31201 atagtctgtt tggggatcat ctcccatata aaaaacatgt tcgctgtatt tgataaatcc
    31261 ttttttacga taaaaagcga gcgcaacatc gttgtgttcc caaacaccga gccaaatggc
    31321 tgttttttgc ttttcttttg ctttttcaat agctgtatct agtaaaaatg taccgatacc
    31381 ttgatgttta aatttttttc gtacatagat tcgctcgatt tctaaaaaat gatcagccat
    31441 ttcctcagat tgactcgttc ctgtatttag tttcaggtaa cccgcaggct cttgatcgat
    31501 actcactagg aaaaaatctg tttctttatc ttttagctct tctgtaagtt tttctagtgc
    31561 ataagcttgt gtcaagtaat cagctaaatg ctccggtaat tatcttttcc aaatgtatct
    31621 gtaaatgttt cgatactaat ttgttgtagt aagtctacat ctgaaggcgt catttttcga
    31681 atttcgtatt tattcacggc ttcttccttt caatagatcc ttttattgcc ttttttgaca
    31741 aaattccaat cttcgctaac attcttgcat actttattta aaagatattc caattgtttt
    31801 gcttcttcgt cagaaagacc atttaatgcg actgcattgg agtagttgtt ttctcgaatg
    31861 atgaaaggat agatttctgc tcctttttta gtcggataga gtttcttgat ttttttattt
    31921 tctttatctt ccaaacgttc gatcatccca ttggattcta atttcttgat tgctcgggca
    31981 gtcgttgtac gatctacttt gatcatttct gctagttttt cttggatgat tccaggattt
    32041 tcgcaaatac gtactaaata aagatactgt cctcttgtta aatcgacttc tttgaattcg
    32101 atattgctaa tagagtctag cgctcgggca atcattccga tgtctcgaag gatttcagcc
    32161 atttcatccc acctttattt tgtttgtaag actagtttac ctctttttgt tgcaaatgca
    32221 actattttta ataaaaaaat caagttcttt tttaataact agtaaagtat attcttttct
    32281 tcttttacga aaaagctcaa tcacaataga tctggttttt gttttctaaa ataagtaact
    32341 gtttcttcgt tgttcgcttt tctgatagct ttggcaactc ttctatacta aaaaatccca
    32401 tgttggaagt ttcattattc tcaataaact tggcctcttc accgtggatc gcacaagcaa
    32461 aaacaagttt ataatactga aaaagctgtg gaatatcttt ttgtttattc gtatcaaaaa
    32521 ctgctcgcaa ctgagtagtt tctactgtta atcctgtttc ttcatagact tctttacgca
    32581 cattttcttc aggagacaat cctatttcag caaatccacc aggaagtgac cattctttcg
    32641 tccgtttatc ttcgattagt aggaccttgc catctttttt gatataggca cgaacatcta
    32701 cttttggtgt tggatgtcct tctccaatcg ttgtgagcgc ttttatttct tcgaaagttt
    32761 cttttcctat ttcactgatc agttccaatg aaatcgtccg gatctcctca aaacgctctt
    32821 tatcaaatac atcttttcca taatatagac cagcttgaga aagtgcgagt agtcttttgt
    32881 attgagccaa cttcttgttc attctcttcc cttctttttt agcaaatgta tgactatgta
    32941 atcaagtata gaagactggt ttaattacgg caaataaata taatgaaatc tgcaataaat
    33001 aaaagaatgt taaaaaactc gagaacaaaa gacattcgac ttctctgggg ctgtgaataa
    33061 atggcgttca aaagcttgca tctgcggtaa taagccccat caaacgaaaa atatgacgag
    33121 ctattcttgt ctggctgttc ttattaattg aggcaggaca gctttttcac aacctcccca
    33181 ctaaacggtg ttctcctacc aactcctcgg tcacaagtca caatattcat caaacatgag
    33241 aagctgtttc tttgaaattg ctccttgtga ctcggagctg aacgacaggc tcacgacctc
    33301 tcggtaaacg gtgttcaaaa gccaattttt cgatattaag ccatttcttt gttacttatt
    33361 gtcattgatt tctttttcta atttatccaa tagtggagtg taatccactt gagtatagtc
    33421 tgttacatca aattcatata gtgttcctaa ctggaatttg tcatattttc ggtcggcgat
    33481 gatctttttg aatgcttctt tcgtaatatg attggtccct ttcgttcgat cttccaatac
    33541 gtcaccatag tgataatgat ccatgatata gctcaaatga cgatctgatt cacgatcacg
    33601 tttgtaccga cgttgccata acacttcaaa gtctgctgtt aggcgaatcg tgatcacctg
    33661 atatccgtat ctatctgcta attcttggag tcgtgctttt tgcttatcac taaaaggata
    33721 ctcggacaca atcactttct ttcctgcttc catatacaaa tcaagtgctt tgtaatagaa
    33781 aggataaact ttcgtccttt cttgttccgc ccgttcttcc aaattgttaa acccgatgga
    33841 ttctgcatag tattccttga tttcatcgag cgtgatggca tacatatctg gaaatcgttc
    33901 ccgtagttta ttcataagat atgtttttcc tgtaccagga ctaccagcca gaagaatgaa
    33961 atactttttc atctcattta tttcctaagt taattggact ttccaagttc ataaacagtc
    34021 caatcttatg cttgacaatt tcttttactg ctttatttgc tggaatcaca ttatggcgaa
    34081 gagacttgtt gatttctgtt tcactaaagg tttctttagc tactttcgtc cagttgacta
    34141 aaagctccgt tccaacattg aatttgcgga tcccgttatt gatcaattca ggataatctt
    34201 cttctttcac acctgttcct ccatggataa ctagggggac atcaactact gcatcgattt
    34261 ctttcagcaa gggaatgttt acttctgttt ttgatttgaa ttgtccatga ttcgtaccga
    34321 tagcaatagc taatgcatcc acgcctgtag cttctacaaa tttcactgcg tcttccggtc
    34381 ttgtatatac cttgtcattt tcagcgacat ggattccttc ttctgtaccg ccgattgttc
    34441 caagttctcc ttctacggaa acaccgtgcg catgggcata ttctactact gcttttgtct
    34501 tcaagatatt ttctttgaaa ggtagatggg acccgtcata catgacagaa gtatatccgc
    34561 tatcgattgc ttctttgata tcatcaaagt ctcgggcgtg gtctaagtgt aagactgcat
    34621 caaccatttc ttcttctgca atagctgtca ttacattgac taacacatgc atgccgatat
    34681 atttagcggt atcgacactt gtttgaataa tgattggcga acccatttct tttgctgcgc
    34741 ctagcatggc aggaagcatt tctaggttat gcgtattaaa agctccaact gtaaaattca
    34801 actcttctgc tgtttttgtt acttctttca atgttgtata catcttttat tgccacctta
    34861 tctttttatt tgtttccttt gatcgttact tgttttgcaa tttgtcgcat ctcatccatt
    34921 ttgcccatgt agtaatcgat cccttgatca tcaccagcac gagcagcatc tgcacgcttc
    34981 tggttataga ggctcatcag ttttttatac ccatctccga tcgtctgttt attttccaag
    35041 ctcttttcta aatattggat ggcttgatcg ttctcatgca attcagaaaa tttaagtcca
    35101 acttgttcat aaagttccgc taatttatgc ctatcttggg tagtggaaat ctcttgtttc
    35161 aattgtgtaa tctctgattg aatcttttcg gtcgcttctg gcgatagggc tttttcttct
    35221 tttgccagaa cttttttcgg ttctttttct tttttcttaa aaaatccaaa catcattttc
    35281 cctactttca attaaaacgc tttcaaaact gggcttaaga tccaggcata taagagtgct
    35341 gcggctactg tatctacatc ggttgctgta gcattgatga atcccatcga attaaagatc
    35401 gttactagca aagcgggcaa taatgtaata aagaaaccat gagcaatacc gccaatgatc
    35461 gctcctcggc gtccgccaac tgcgttgcca aatatccctg ctgtccctcc ggcaaagaaa
    35521 ttggttagca taccaggtaa aatcatcgct aagccgaaca tgggcaaagt aaacatggca
    35581 ataatcgtac caatcgttgt cgtaatgaaa cctaaaatga cggcatttgg gctataagga
    35641 aagaaaactg gacaatctaa ggcagggatc gcatcaggaa ctaatttcat agctatccct
    35701 cgaaatgccg gcacgatttc acctaacagt agacgtacac cagctagcaa tatatacaca
    35761 cccactacga attggatggc ttgtaaaaag gcaaacatga tatagttttg atctcctgat
    35821 aattcagaag cgaatggttc gcctgcaaat aaaacagtga tgatatatag cgggaccatc
    35881 acgaccatga cagacaaata agtatcttgc agaaattcga aatgtgtcgg caacttgata
    35941 tcttcgatcg actttttatt ttcgcctttc tcaccaaaaa gcttagcaac accggcttca
    36001 aataagtacc cgatcgtaca aaaatgacct aaagcaatat catttgatcc agtgatttta
    36061 cgaatgatcg gttgcgctac tgccggcata gcaatggcga aacaagctcc gataaaacca
    36121 ccgaccaaga tcaatacgat ccctcgcaga ccggcaaaat agccaaagac tgtcgtcatc
    36181 gttgccatcc ataaaattgc ttgaccagtt aaaaaaatgt acttccattt tgtgaaacga
    36241 gccaaaataa tattgaatac aaaaatggct aagaacgtca gtgcaatatc tctacctaaa
    36301 cccaaatcat tcattgcttg atcattgata gattcaatag aagggatgat cccttgcata
    36361 tgaaatcctt cagtaaagat tttcccgaaa taagttaaac ttccaacgat gatgctcgaa
    36421 ccggcactca atacttgaaa tcctaggagt gtttttaacg tgccagagat gacttgtcct
    36481 gctgatttct tctgcagtag tagacccaac atagcaatca atgcaatggt gatcgatgcc
    36541 tgagtcaaaa tattttcgat gataaaattg ataacgctca tgtttttacc ctcttttctt
    36601 tttgtattta gataactccc ttatcttgca gaactggggt gattttttct tcaatttcat
    36661 tttttgaaac aatatttttc aaatagatca tcgccgtttt aggatcaact gcgaactttt
    36721 cgaactgcga acgaaaattt tctgctgtga tgatcacatc tggtttcatg gaaactgcgg
    36781 aagaaatatc acaatggtcc agtttggctt ctactcctaa tttgttcaaa acatcctcag
    36841 cagacatctg tgctgcaaaa ctacttccta aacctgcgcc gcatacgaat aaaatgttca
    36901 atttgttcat ctttgttctc ccccgtatca tttattattt ctcaactact gaaaaaagca
    36961 gttgtttgaa atcttcgata tttgtgcatt caatcaatcg atccaacttc tcttcgttgt
    37021 tgatcaattc aattagttct ttcatgatgt tcagatggga gtaggagtct actgctgcca
    37081 aacaaaaaat aatctttact ggatccattt caggattacc gaaatcgatt ggttgctcaa
    37141 tcgtagctac gctgactcct aatttattga ccccatcttc tggtcgggca tgggctagtg
    37201 ccatgtgttt gccaatcacg atatacggtc cgtaatcatt cactgcacga atcatcgctt
    37261 cgacatagcg ctcttcgaca atgttttctt taaccaatgg tctagcagct agttcaatcg
    37321 attcctccca agtagtggct ttttctttga tcatgatatt gctgtccgtc aaaatatctt
    37381 ttaacatagg ctggatctcc cttttgttga tttctaaatt gtttgtttcg aataattttt
    37441 ctaacttgcc atagatgatt cgatctactc ggccaccact ttctttcatg acatctatta
    37501 tttgagtgaa taactccgtc gattcatgac tgttaggctc taaccgctgt agttcttcat
    37561 ttcttttcaa aaagtcttct ataaccaaga tattcgtctc agttaaaatc ggatcgacaa
    37621 ctaaaagcgg cttatttcga taattcaatt gaaaggtgct gaaaaccaga ttgacatcca
    37681 atttatctac taattcgatt tcttttgaac ttaaaactgc agtaatctcg atctgaggaa
    37741 acttttcttt cagattctct gctaacagat ttccagtagc catcccatgg ttacagacaa
    37801 cgactgattt ataaacataa ttcaagtctc gcttgattac actggcgatc gtcgaaaagt
    37861 ggatgacaag aaaagctatc tcgtcctcca gtatcttgcc accaattact tcttcgatcg
    37921 taggaacaaa atgagtgact gcgcggtaga ttgggaaata atttgttcgg atgttttctt
    37981 tcaatggatt catgacttgg atatgattct tgattcttac aatcagtgca gccatgtgct
    38041 tatagagatt ttcgaataag gcttcttcct ttagatggaa aggtacgtgt gtctcgttct
    38101 ctacaaattg gatcaattgg atcgttagta attgagcttg tacccactcg attgaattgg
    38161 agatatctct agcattgaac gtctcaatag tgaaacgaag ataatttctt tctacttgcg
    38221 ggacattgtc caattgaaat tcctcgatca tgtggtcaat aaatgcagaa aagctactgt
    38281 cttttatttc tgtatttttc caattaatgg cagagataaa ttcatgtttc ctgattcgct
    38341 ggatccagat caatgtaaaa agcaggattt gttttttata aatatcatct tcttgtttca
    38401 acaacttatt ggaatagatc tcctgtattt ttttgatttc ctccaaagga aaataatgga
    38461 gaaagatttt ttgagccggt gttaattgtg catcttgatt cataaagaag tcggtcattc
    38521 ccagattctg attgataaaa tcatagatca tcgtacggat agatcgttct gaacctttat
    38581 aaaccagtcc ttgctttcca taactgacga tctctatccc ataactgacc agtgttgctc
    38641 gtaaccgtct catatcttca tctaatgtac ttttagagat ttgaaattct tcttcttttt
    38701 tgtttagatg gatcgggatt cggctgtaag caacggctaa aactagatca aaaatacgtt
    38761 cgcgccgatt caaaaagccg tctttcacat cttttatttc agtttctaat cgagcttgct
    38821 tttccttttc cagcttcaac aaaaaacctt tgttgcgaat tgtacggatc tccggaagct
    38881 ttttactgct caaccagata ttcgcttcaa gaacttcctg acgaatcgtc cgctgactga
    38941 cattgaactc acttgctaga tgttttgctt ttactggata ttgggctgtc atgattctgt
    39001 gaagtatttc aattgttctt gttttcatag aaatgatctc cttctgattt caagtatatg
    39061 gttccgctta cataataaaa agtagatatt tctgccactt gaagtggaaa gaaagtaagc
    39121 aaagcaaaca aaaaataagc catatgcttt ttcatctcct caacgaaaaa gacatacgcc
    39181 tattattaca aaaattttgc ccatctatac aaaaaagagg ttgtgaaaaa gctgtcctgc
    39241 atcaagtaat aagaacaact aaactaaaat agtgcttcct attttttgtt tggttgttct
    39301 tattatcgca gatgcaagct tttaaacacc atttagtgga gaagctgtga cagagatgtt
    39361 cagccttgag cgataagaag cgattttgaa aaatcgcttc ccatatttta caaaatcgtg
    39421 ccttattgcc gataggctat ctctggaaca ccgtttattc agaaaaagga gctgcgacaa
    39481 ggcttttgtc acaactccgt tcataaatat ttcctgtcaa tccagcataa tcggttgaat
    39541 aaaatcggct tgccatcttt tttctttctc agaaaaatca aaataccata tctgagaaaa
    39601 atactgtcgt tgtgtcttac ttcctgagat caatcgccca tcttttcgat cgactgaata
    39661 atcacagcat ctgaaatcaa ttcggatggc aaaactattt tcgtggatct gtcgataatt
    39721 tcctacttcc tgaatagtta tttttttagt atgatttctt acaccgtctg ctttgttttt
    39781 ttgcagaact ttctgatgtt cggcaaacag cttgtctgta taacagcttc tggctttttc
    39841 aggagtttct tcttcccaag cggattggat cttcatgaat atcttttgga tttccaaaaa
    39901 ctgtgctttc ttttctttag ccgttcctga catgcgggac aatatctccg atttcagcct
    39961 tttcttttgt cttttattct tgacgataga aaaagcagaa acccctccta ctgacaaaac
    40021 agctaatgca agaaaccccg tttgctcata actagaagga cctgtacttg gaccataata
    40081 cccataagaa tctctgccgt aagaacgact gccaaaataa ctgcccccat atgaacgacc
    40141 gccaaatgaa cctctgcccg aacttcgacc gctagatgta cctccaccat gaccacccgc
    40201 gacagcgaat ccttgggtcg gcagagcaaa caaacatagg cccactaaca aaatgattgc
    40261 taaataattg attttttcat tgtcttcctc gttatctttt attacaaaaa actattttta
    40321 tcatagcctt gctaaaagga agagtcaata accagatgca taaactgttt ttttagcaat
    40381 tttgtcttat ttagtcattg agtaacatcg gacagatgta tgtgtcggca gtccataatt
    40441 cctctatctt cagcatgaac aagcttgcag acaagagatc tgcgcttcct ccaggagaga
    40501 tttggttttc ctgacaaaag tgcaacagtg ctgtaaatgg acgatttggt aaagcacttt
    40561 gactagcagc atgagcaagt ttttgcattt ccactaacgt tttctgatca ctgcgatgca
    40621 atacgcatgt gtcatctagc gaactcatca aaactaacaa catatgcatt tgtttctgta
    40681 catatgaatc attatctagc tccttagctg cttggattgc aagcctgata tgcggatacc
    40741 ctaatatcgc ttcttcatat gcaccattta cgccatattt ttgcttcacc ctatgaccat
    40801 gagtggtttt tttatgacga tattttgtat caggaaaagc agcaagcttg ctgacatcat
    40861 caagtatttt cgataaagaa aaaggctgtt ccatactgat tttttgtgca atgacactga
    40921 tcaatagccc cattgcccaa atcgctcctt tatgggtatt gatgccattt gtagcaatca
    40981 gcattgcctt ttccgctttt cgcccaatct cagcaattct ttctcttaac tcctgatcaa
    41041 tagcataatg ccatgctatt tgagccattt cttcaaaaaa aggagttagc gtcttagcag
    41101 acttatccaa aatgcgccga ccttctttta cggcttttgc gatcgtatgg aaattatcat
    41161 ctcctaaaac catatcagct gcctgtttgc ttacttcact acctttgatt cccatagcga
    41221 ttcctatatc ggctcttttc aaagcaggtg catcatttac gccgtctccg gtcattccga
    41281 cgatttctcc atttttctgc aaagctttca cgattcgcag tttgtgttct ggtgtcgttc
    41341 gagcaaagac gtcgactttt ggtacttgtc gaatcaactc ttcttcagac ataagatcca
    41401 aatcgatccc ttctaaaact ttagcagtat gttttaagcc aatttgttcc gcgatcgctt
    41461 ttgctgtatc tttgtgatcc cccgtaatca ttttcactga gattcctgct tgttggcatt
    41521 cctttacagc tttgactgca ctttcttttg gcggatcaat caacccagca atccctgcaa
    41581 aagttaattg ggttaaagac tcatgcgtga gttcctgttt cgaatctact tttttgtaag
    41641 caaatcctaa aacacgctga ccttttttcg caaacgctgt ggctgtttga ccccatgctt
    41701 cttattctga agaagaaaga gttgatttag ccaataatac ttctggcgca cctttgacgt
    41761 aaatcacccc tcctttttcc tccgcatgca tcgttgccat atatttgtat tcagagctga
    41821 acggaatttt tgcttctatt tttttcaaag gcagatcggc tgtttcggtg tggcgaatca
    41881 gtgcaagttc tgtcggattg ccacttaaat tttctgtttt ctgttcttct ttcgtcttta
    41941 attcctgaca atttttcata ataaacagta cgcgagtttc ttcctttgct gctacatcca
    42001 caactgtcat ttcatttttt gtcaatgtcc ctgtcttatc tgaacagatc actgtcatag
    42061 aacctaatgt ttctacagaa ggcagtcctt tgatgatcgc cttttctttt gccatttcat
    42121 gtactccgac agataggatc atggtcaaca cagctggcaa tccttcgggt accattgaca
    42181 ccaccaaagc gatcatagct gaaagaagga tatgccaatc catgccatag cggaatgttg
    42241 taaaaacaac taagaacaag atcaaacaaa gaatgccttg aaaaatttgt ttgttcaatc
    42301 ggttgatctt cttgatcaga ggcgtcgttt gttgttcgac cgattgcagt gcttgattga
    42361 ttttaccgat ttctgtcgtg tttcctgttt ctacaacgac accgactgca gaaccagatt
    42421 gtacaagcgt tcctgaaaaa gccatatttt tttggtcacc gattgattct tctgctgcca
    42481 aaacggaatg atttttttca gatgcttctg attctcccgt caaaatcgat tcttctacta
    42541 gtagatcatg tacttcgatc aaccgaacat ctgctggaac gacgtctccg gcacgtaaga
    42601 caatgacatc tccttttact agttctttcg cagggatttt ttcttgcatc ccgttcgata
    42661 gtactatcgc ttcttgtccc atcagctgct tcaaaccatt caacgattct tctgcttttc
    42721 tttcttgcca ataactaacg agtccgttga cgatcactac gaataaaata atacttcctt
    42781 cgatgtattc gctcgaagca aatttcaaaa aagaggcaat gatcaacacg atcatcagca
    42841 gatcagtaaa gtgttttgct atttttttcc atcgttttgt ctgctgtctt gcttctatct
    42901 cattatatcc ttgatcagtc aggcgtttct gccgttcttc ttgcgacaag ccttctgttg
    42961 atgtttgata gtttttcaat acatcttcta ccgtcaatct gtaccagttc atcctatccc
    43021 ctcctgttta attgatactg ttattatacg cagggaagtt ttttcaggcg tatcgattat
    43081 ttcagggggg tctgaaataa ttcgttttgc agaatgtatc tgggcctaac tgatatttct
    43141 attgcttatt cttttatata caaaatttaa gaatacaaac cagataacca ataaaaaagg
    43201 aataaagcgt gtcgtgcttt cgaataacaa gctgaaagca attgaagtaa aaaacaccaa
    43261 caaagcaaga tctttatatc tttgtgtagt gttccgtttc ttttctttaa taaattgaac
    43321 atgtgcacac aagatcgaag accacacaaa tagaaaacaa ctcgttgtca tgcctgccaa
    43381 aagctgaaaa aacaatcgac tatcagctac aaaaaaatgt agacaaagac cgacaaaaaa
    43441 taacatccct gtaattaaaa taccgtgtaa aggtacgcct ttcttagaaa gcgcacaaaa
    43501 ccaatggggc aaacttttct cttttgctgt ttgatataaa atcctgctag tactgtagac
    43561 tgcactattt gctgaggaca aagaagcaac caaaatcatt agattgacaa ttgctgctcc
    43621 gctttggcaa tggatcactt gcagcatagt cactaaagga ctttctttta aatctaaaca
    43681 atgccatgga acaacaaata aaatcgacaa aatcgttcct atatagaaaa agaggatacg
    43741 ccaaggcaga cagttgattg catttttcaa attcttttgt gggtcactcg tctcaccaac
    43801 tgttaatccg atcatttcaa ttccagcaaa actgaataaa accataggaa atgaagcaat
    43861 cattccagca aagccaaacg ggactaattc attgagctgt ccaaaatttg ctttgattcc
    43921 aatagactgg gtatgaaaat ctgagacact caatcctata cccaataaga taaaaaggaa
    43981 aatccccaag atcttgatga ttgagaaaaa agattccaat tcaccaaacc acttgactgc
    44041 aacaaggttg actgccatta agatcattag tgcgctacct ccgcttatca aagctggtac
    44101 atgtacaaac cagaaatgga tatacaatcc tattgctgtt aattccgcaa gtccagctcc
    44161 aagccagcaa agccaataag tccaattgac aaaaaatgcc cactttttgc ctaaataata
    44221 gtcaacgaaa tcactgatag agttaaatgt actatttgct aaaaataaat cacccatgac
    44281 ccgcatcaaa ccataaatag ccaaaccgca tatcaaataa acgagaataa cagctggccc
    44341 tgctgatgca attgcctttg ctgaacctaa aaataatcct gttccaattg cgccacctaa
    44401 tgcgattaac tggatatttc gattagttag agtccgtttc attgccggtt tttccatcaa
    44461 gttcaccttt ttctttttca agcagcatgg cgacttcctg ttcccaagaa ggtttcttta
    44521 ttttttcaat acagagtggt actacaaaca aaatgacact gatggctgtg actgcaatta
    44581 gattgatcca tgtcccagct ttcatcgtca gtccgacaga aaatccgatt gccgcaaata
    44641 aaacaataac gacagtccaa actccaagat tgctcttttt ctcttttttt ccaattctaa
    44701 atggtcgatt caactttgca tgtgtataac gcaatctcaa aactgcgatc cccatgatga
    44761 catagacgat acagtagata acagtagttg aatttacgag catcaaaaat gcttgattga
    44821 cgccaggaat cagcaaataa aaaagtgcaa agattgagat aatgacagac tgagtcaaaa
    44881 taacggattt ggatacgtca aattgattcg tcttccaaaa attgaatttt ggtggatacg
    44941 caccttttct agcactttct gtcactgtct ttgctggtcc tgaggcccaa gcagataatt
    45001 ggactgctac accaatgaag acaagtaaac taaacagatt cacaataaga tgtggcaaac
    45061 caagaatttg gcaataaatc gaaatagatt gcgcgatatt attcaattcc atttgtcctt
    45121 ttggtacgac atttgctaca actaaagcat tcaaaatatt gacgaaaaat ataaaaatta
    45181 acgcggcaaa tactccgcga atatacgttt taactggatt tttcaaccga gtgatataca
    45241 cagaggacat ttcgatacca gtaaaaataa acatgatcgg cgcaaaataa acaaatgagg
    45301 atgcagtcgt agtatctggt attaatttgt cccatgaaaa actgcctaat gttccggttg
    45361 gtacgatccc aactttgatc cacgcagcaa accctaataa gagcatcatc gtcaaaggca
    45421 cgtacaatcc taaccaaaca ccgacttttc cgccgatttt tgccatatca aatttcaaat
    45481 tcaaaaaagt gatgatccaa taaacgacta aaatgacaac taatgtaaat ttgctgttca
    45541 aaccaagcgg cacattatcg ataatattac caaacaacgg agcaagtgct gaagcgacca
    45601 tcaccatccc aggaaacatt tggacccata acagccatga gacaacgaac ccccattttt
    45661 ttcctagagc attcgatacc caaagttctg gaccaccttt ttggggaaac attccggcaa
    45721 attcaccaga gatcaatgag attggaaaag cgtacaataa tactgcaacc agcatgtaaa
    45781 aaatcatcgt ccagctcgtt gctgctacat ctggaatatt tcgtacactt gctacaaggg
    45841 cgcaggtcat tccgataaag gtcatggtcg tgatttgctt tgatgaacca gtatctttca
    45901 tctttattcc ttctttcaat agcgacatat gtttttgttt tcttttattt ttgttcaaga
    45961 acagaaatga caaggtttca tcgattcagt acaaaaccca gtatcaccga aacatccatt
    46021 gaacgatctt agtgaactgg gtttgataca tgaaacgaac gatccaactt atagaacgtt
    46081 ttataaaaaa gaatatcttg gcgaggaata tatgaaaaac agggggaaat acaattgttt
    46141 tgatgaagca aataattgtc tgttctccat atgtctcttg ttattctttc acacaaaaat
    46201 cagttctatt ggatgatttc gtttagtttc ttttccattg ctttggcgat ttcttttgta
    46261 taaaaattga aaattcgatc atcattcaaa taaggagtca tgatagccgc acgtagcaga
    46321 gtgattttct gttctttttt ccattcttct ttcgttagac ccattctttc aacaaaacga
    46381 atcggagaat caccgtaatc ttcttgtgta aatgtagtat gagaagtaat aaaccgttca
    46441 ccataaacat cgccatccat ataagaagac cgatcgaaca ttttttcatt taattcattg
    46501 atagcgttca aatctgtaca gccttgttct ttgaataccc aattgaccat attaaaatca
    46561 ggatgattca atggatagac ttcgattgtt tttcctttaa cagtaaaagt cagatgatcg
    46621 agaaattctc tgaatctttg agctgcctcg attgaagccc caatcaattg accatatccg
    46681 gtcacattca atggcaatac acgatgtgct gtccagactg cggcggcggt tgctccagct
    46741 tttgatcctt ccaaaatata agctcctaac atatctggag cctttactga tttttcaaac
    46801 acatatggcg cgaaataaga aatgatattt ctcatatttt tatgtttgat tacgattcct
    46861 ccagcagcat aagggacata gcccatctta tgaggatcta tcgtgacaga atccgcttct
    46921 gaaatagctc tgaacccttc atatacctct ttgtcaatcg ttacgcagtg gtggaaaaca
    46981 tgatgttctt caaagaattc agctaaggaa gcatacggca caaattctcc tgcttcgttt
    47041 agaaacagtg aacgcgcata gccgccatat gcggcatcaa catgtaaata gaaatagatc
    47101 ccttcatctt ttaacctttc tcttaattgg acgattttat ctacactgtc tacttgacct
    47161 tcttctgtcg ttcctacgac agcaaccaca cctagaattg ggattttttg ttcagctaat
    47221 tcacgaattg ttttttccaa agcattaata tccattcgat aatcctcttg aactgggata
    47281 gcaaccatct gatctaagcc tactccgcaa atatctaacg ccttcatcca agaatagtgt
    47341 tttgtttgag gcaccagcca tttccctaat ctttggatat tttttccgct acgggaagaa
    47401 gctgctttga cctcatccat ttcttcgtcc gtaaagcttt cggtcatttc caaaatttct
    47461 tcaacagata aattcaaaag ttcccactca gacatttttt tcacttgttc aggcagcact
    47521 tccttgacag ctaaaggaat cgatttgatg cagcgggcgt accataatcc ttcaagatta
    47581 gcaatagaac catctgctgc aatgtgtccc catccgtctg tcatattgaa taatgaagca
    47641 aaatcctgtc ctacttctgc ttccatttgc gaagttgcca tagaagattc caatgcaaca
    47701 ttatttgggt tccacagcat cgcatagttg taagctaata aagcaggcat caatgtttca
    47761 gcattcattt gtccccagta acggcctgct gaatgccatg ggatcgatcc tgcgcgtaat
    47821 cgctgactga cttcatccaa gacctctatc atatggtcgc gggtggctag ataatctgga
    47881 gtgagcttat ctccttcgct aattgcaggc atatctgaag gaatataatt ttctctccat
    47941 ccaagatgtt catctaccat cttgttcaac aacattttat aaactggtcc attttcagct
    48001 ttgtcgccta taaagacggc cttgatatcc atatctttca tttttcttcc ctccatattt
    48061 tgttggtcaa tgtctcgcag atacatgtgt ttatctgtaa cacctcttca ctatagcgcc
    48121 aaaaatgaga aatttttttt tataacatca aatccacgta gatttttaca acgcgaattg
    48181 taaaattaag ttagaaaaat aaaaaggcat ttatggtaca ctcaaattgt atttccgacg
    48241 aaagaaaaca aaggagtgta accataaatg acctacaaac atcttaccat agacgaactg
    48301 acaatgatag aatcatatta tcttcaacat aataagccgg ttgaaatcgc taaccgaatg
    48361 ggacgtgcta tacaaactat ttataatgta gtcaataagt tcaagcaagg caagactgct
    48421 cttgattatt ggcaccagta taaagaaaat aagaaaaaat gtggtagaaa agtcattcaa
    48481 ttacctgctc atgaagtaga ttacattaaa gagaaagtca ctcttggttg gacgcctgac
    48541 gtcattatcg ggcgaaaaga aaggcctgtt tcatgcggta tgagaacact ttatcgttta
    48601 ttttctaaag gaatatttga tattgacaca ctaccgatga aaggtaaaag aaaacccaat
    48661 ggccatcagg aaaaacgggg aaaacaacag tatcagcgct caatccatga tcgacctgat
    48721 aattatcctg atttcaattc tgagtttggt caccttgaag gtgatacgat cgttggcatt
    48781 catcataaaa gtgccgtcat tactttagtt gaaagattat ctaaagtcat tatcacgatt
    48841 aaacccaacg gccgtaaggc attagatatt gaaactgccc ttaatcaatg gttttctcgc
    48901 ttccctaaaa acttctttaa atctattacg tttgactgtg gaaaagaatt ttctaactgg
    48961 aaagccatta gtaaccaaca tgatattgat atatattttg cggaccctgg aacaccttct
    49021 caacgcccat taaacgagaa ttctaacggg attctgcgtc gtaatggact gccgaaatca
    49081 atggatttta gaaaagtgaa tcagacattt atttccagtg tcagcaatca acgtaatcat
    49141 attccaagaa aatcattgaa ttacagaaca ccaatcgaaa tatttttgag ctatgtacaa
    49201 gaagcatttt attctagctt aatttgacaa atcataacct ataaaaaaac aaaataaaaa
    49261 agcagaaata actggctatt tctagcggat tatttctgca ataactaatt atctattttt
    49321 tattttcaat taatttaaag cttgaccatg gtttcaaaaa gtcaaggagg aataattcgt
    49381 catcggagat tcttcctaca acattgacac gtccgtcgtt tttcatatcc ttcaaggcga
    49441 tttgtgtttc tcctttgtat tgaccgtacc cttcattgtc aatcagtaca tccccatgat
    49501 gcatatctcg cgtattatga ggcgggaaat ctttatcttt gtagtataca cgagtcatcg
    49561 ttgaacgaag gatatattct gagcgatccc ctcgataact atgaaggtta tcaaacaagc
    49621 agattcgttc gttttctgta ataccttctt ccgtatctac tttcaatgtt ggataatccg
    49681 cgttaaatgc ttctgccatt tctttcaatt cttcttcact tgcgtacgca tttccaatag
    49741 aaatatcatc aatcaatcct gtaaggatta aatgcttcac ttgtgtcgca atttcaagat
    49801 ctcggtggtc ttccagcgtg cacaagccat cttgcgtagg ccaagggcca aactcagcag
    49861 attgcgaatt gacgaatgcc atcgtattca aattatattt tctgaatttt tctgaacaaa
    49921 aaacaaagtg ttcgtatcct aaaccagagt atcgatgagg ataaaaatta tgagaaccta
    49981 ataaattatc cgtgtttggc gaataactca tgatgttgtc aacgtaattc gtgcccgaac
    50041 tcatattgat ctcgattttg ataccaaaag gattgcgcgt catttttgct tcttctgctc
    50101 ctgtgaatcc gatatctaag cggaccccgt aggcacccat cttatggaaa aaagataagt
    50161 catcgtaaga aatctccaac tgttcaaata acgctggatt gatatcaacc attacttcca
    50221 tgcctaggct attcgcgtaa tcaactactt ctttaaattc tgaaagaact ttttctttat
    50281 catcattgat ctgcagcaaa ctggtaaaaa cccgtttata cccatactta tgagctaaat
    50341 ccaagtacgc tttgtccttt tcaaatgttg accgttctgg ataaatcgag attcctaatt
    50401 ttcccatatt accatttcct cctgcatctt ttcgtttttg tatccactta cattatagca
    50461 aacacaaagt aaatggtcta caccttttct ttttctttta aaataaatga taaattccaa
    50521 taatttaagt aggtattttc cctctatttt gttatcatta aagataacaa aatagtaaat
    50581 tggaaaggaa cagttatgaa gaaaaataaa gttattttaa gtattagttt agcagcagca
    50641 ttgctgtttg ctgctggttg ttctgcaaac aacacgactt cttctagttc gtctacagaa
    50701 agttcaaaaa gtacatctac tgcggaaagc acgactgcca gtagcgtcga tttgaacgca
    50761 ttggaattac cacaattgac gaaagatgtc gccgaaaatg aagatctggt cgaaatggtg
    50821 acgaataaag gcacaatcaa aatcaaatta tttcccgaac acgcaccaaa agcggttgaa
    50881 aactttatga cacatgcaaa agacggttac tacaacggac tgactttcca tcgcgtcatc
    50941 aaagatttca tgatccaagg tggcgatcct aaaggcgatg gcactggagg ggaaagcatt
    51001 tggggagaag gatttgaaac agagatcaac aaccaccttt ataatataag aggtgcgtta
    51061 tctatggctc gctcacaaga tcctaacagt aacggcagcc agttctttat cgttcaaaat
    51121 acagatgata tgcatgatgg tcttttaaaa gacgactatc ctcaagcaat catcgacgct
    51181 tataaaaacg gcggttatcc ttcactagat ggccattata ctgtcttcgg ccaagtgatt
    51241 gaaggaatgg atgtcgtgga tgctattgca aatatcgaaa cagatagttc agacaaacca
    51301 aaagaagaag taaaaatcga taaaatcaat atactgcaag aagcaaaaca aaaataaaaa
    51361 aataacgtct gaatcctgca tagatgacaa cgtatgctag gattcaggcg tcttcttttt
    51421 acataaaaag caagtaagct tccttttgtt ttgctatatc aggttttata gtcaagcatt
    51481 ttggttgacg atgaacgtga actcgcactc acagactttt ttatcatcta catatgctgc
    51541 agataacgct gtaccgactg atcccttcat tttggtgatt tcaaaatgac atttcagcac
    51601 atctcctgga acaacttttt gacggaattt ggccttattg atcccaccga tataagctct
    51661 ttttcctaga aactcttctg attttaggat aagtatcgaa cctgcttgtg ccagtgtttc
    51721 tagaatcaac gcacccggca tcactggatt gtcaggaaag tgaccttgga aaaaatcttc
    51781 attgattgtt acattttttg tcgcaacgat cttttttcct ggttctaaag tatctacata
    51841 atcaatataa caaataggat aacgattagg aatcaattcc attacttcag tagcagataa
    51901 tacgtaagac ataattaaac tccttctttc aggcaattgc cattttcatt actttgacta
    51961 tcaaagtatc atattcctaa atatttagca atcttttttt aatttaagaa aaaatagttt
    52021 gacaatcaaa acattttgac taataattaa gaaatcaaga agttatttta gctattattc
    52081 tctatttttt tacgactatc aaatttttat cagaaacaaa ggagagtcat tatgtcattt
    52141 ctagaaggaa aaaaaatcgt cattatgggc gtcgctaaca aaaaaagcat tgcttggggt
    52201 tgtgctgaag caatgttgaa acaaggggca gaaattatct atacttacca aaatgaacga
    52261 atgaaaaaat cattagtcaa attggtcggc gaagaagcat tcactgtaga atgtgatgtt
    52321 tctagcgacg aaagcatcga aaaagcaatg aatgccatcg gtgaatatgc tggggagatc
    52381 cacggccttg tccatgcagt tgcttacgcc aacaaagaag aattgtccgg aaatgtgtct
    52441 gatatttcca gagacggcta tcaattagct caagatatca gcagctactc tttaattgct
    52501 gtatcaaaat acgcacaacc gtttcttgca ccaaacagcg ggatcgttag catgacttat
    52561 ctaggttcag aacgcgcaat cccgaattat aacatgatgg gtattgcgaa agcttctctt
    52621 gaagctgcta tccgttattt ggcagctgag ttctcgccta aaggaattcg ggtcaatgga
    52681 atctcagctg gggcaatcaa aacattagct gtcacaggtg ttaaagacta tcaaaaactg
    52741 atccagttat ctgaatctcg tacgcctgat cagcaaggtg tgacgatcga agaagtcggt
    52801 aatgcttgtg ctttcttaat cagcccactt tccagcggaa tcatcggtga tattatctac
    52861 gttgacaaag gtgtccatct ttcataaact tttgttgcat tctttaaagt aaaacatata
    52921 aaaatcagga aaaaactttt taaagtctct tcctgatttt ttctttttac gtttttttca
    52981 actcattact ttgaaattat tccacgactt caatccagcc ttctggtgct tctatgtctc
    53041 caaattgaat acctgtcaat tcatcataca accgttttgt tactggtcct acttccgttt
    53101 cactataaaa tacatgaaga ttgttattgt gataaatccc accgattgga gaaataacag
    53161 ccgctgtacc acatgcacca gcttctgcaa attgatctag atcatcaatg aaaatatctc
    53221 cttcaattgc ttgcagtcct agtcgttctt cagctaactg caacaaggaa tatttcgtga
    53281 tacttggtaa gatagagggc gattgcggag tgatgaattt tccgtctttt gtaattccaa
    53341 agaaatttgc tgcacctact tcttcgattt tcgtatgtgt ggctggatca agataaacac
    53401 aatctgagta atccagttct tttgcttctg ttcctggaag taaactcgct gcgtaatttc
    53461 cgccgacttt tgctgcacca gtccccttag gagcagcacg atcgtaatca gatacaataa
    53521 aattcgttgg ttttagtcca cctttgaaat acgctcctac tggcgtacag aagacgacaa
    53581 ataaatattc tggagctgga tggacaccaa tgttttcacc gaccccaatc agtaaagggc
    53641 gcaagtataa tgtagcgcct gttccatagg gcggcacaaa atcttcattt gcttttacca
    53701 cttgcttgac agcatcaacg aacatctttt cagggaccat tggcatcagc aatcgtctag
    53761 cactttgatt catccgtcga ctattttgtt caggtcgaaa gagattgacc ttgccgtctt
    53821 ttcgacgata agcttttaga ccttcaaaac attgctgacc ataatgaagc gctggagagc
    53881 cttcatgaat cgtcaggtaa ttatcttctg tcaattctcc ttcttcccat tgtccgtctt
    53941 tccatttggc aataaaacgc caaggagttt tgatataaga aaaacctaga ttgttccaat
    54001 cgatttgcat atacttacca ccttcgttat tttctccaca ttttatcatt atccatatta
    54061 tttgtcattt tattttcagc ttttttcctt cattatagtt atttttgcta tttccttttt
    54121 tgaaaacttc ttggtacaat acagaaagaa tcaaatttta gaaaagagga ttttatgttt
    54181 tcattattag caactgccgg tacgacagac tcttctggcg agacattgac agatcaagct
    54241 gtcagcaaag taaatgcgtt tcagcggttt tgggacggga ttgattggga cgccattttg
    54301 gctgccttta tccaaaaaag tttatatctg atttttttga tcgtcctttt ttggattctt
    54361 caccgtgtgg gaaaatatct gattgataag tcttttaatc agtattctaa aaaagccatt
    54421 ctaaacgaga gccgcttaaa gactttacat agtcttttaa atactatttt tcattatacc
    54481 cttggtttct tttttatcta tgcaatttta tctgctatcg gtgtgccgat cggatcactt
    54541 ttggctggtg ccggaattgc aggtgtggca atcggtcttg gtgcccaagg gttcatgagt
    54601 gatgttatta ccggattttt tattatcatg gaacaacaga tggatgttgg ggactacatc
    54661 aagctagcaa acttaacgat tgaaggaacc gtcgtatctg ttggtatccg tacccttcag
    54721 ctgaaagcaa cggatggtac tgtccatttc atcccgaatc gaaacatcac cacgatcagc
    54781 aatctctctc gtgcaaatat gcaagtactt ttagatattc ggattgttcc tgaagaagga
    54841 tatgacaaaa tctatgagat cattgatcga gtaaatcgta cattagctga aaaataccaa
    54901 gaagagctcc aaactgaacc ttctatcttt ggattagtgg atcttggaaa cagcaatttt
    54961 gcgattcgta cggtctgcta cgcattgaac ggaaaacaat atgccttaaa agaagagttc
    55021 ttgagctcct atgtcaaaga attgacagct tctggtttca cgattccgaa cagtccaatt
    55081 gctgtcggaa aataatttgg acaaacgatg caacgaatct cactaaaaag agcgtgggac
    55141 aaaagtaaag aacacttttg tcccacgctc taaacacgta taaacggcgg aagcagaagc
    55201 aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt cgtgaattcc
    55261 ttcttatttc ttggagttaa acgcttttgt cccagcctct ttttcaagat aaagtcaaaa
    55321 ctggtacgct gttttttcta cttatttttt gattatcttt tagtttctcg ttctttagct
    55381 cacgatatcg atttgttctt ttaattcttc gattttcgga gacaatatat tacgacgttc
    55441 taattcatgc accatgaagt ttacggcttt aagcagctct tttcttgtaa tgattccttt
    55501 gaaaatccga tcttctgtga caaccggtaa aaaaggcgaa tcgactaaca aatggagtac
    55561 ttcttctagt tcccaatttt catcaattgt cggaacatct gtttctgtca catcagcaac
    55621 cgttagtcct tctaacgggt ccatgctgat tgtttgcaag tcaatcattt tattgaccac
    55681 atctgataaa cttactagtc ctacaaagtg atcatctttt cctaatacag gaattttgga
    55741 ataaccgacc ttcgataaca caagtaaacc atgggacaat ggatgatgat acataacatt
    55801 tgccacattt tctgcaggaa tcaaaaacgt ttcctgattt tccagcagca tttctcttac
    55861 tataggtcca atcatctgat ggcctccatt tctatttcat tcaacactac tattttaccg
    55921 aaaccggatg caaaattcat aaaataaagc ttatttttat taaaaattag agttttttta
    55981 ttcagcgctc tctcgaaaaa gaaaaggcca actcttcaac tgcctgatgg gcacggttat
    56041 agtattgaac agaaatttgg tcatctaaac tttcgataag agcatatgat gggatttgga
    56101 tcgggcctct aggctgagaa atgctaccag gattcaaaaa caggattttc tgatccatct
    56161 cacagcctat ttgatgggta tgaccaaaaa acaccatatc ggcagttgca gctcgagctt
    56221 cgattgctaa ctgtgtcaaa ccaaatcgga cattcgataa atgaccgtga gtcatgaata
    56281 ctgtatcctg accagtttgg atcacttttt tctgttcgaa tcctggtcca taatcacaat
    56341 taccttgaac cacttggaat gtatcccata atgggtcaga agcttctaat tccgaatcac
    56401 cacaatggaa aaagatatcc acttcagaac gataacgatc tactaagtca acgaggatat
    56461 ctctgtctcc atgattatca cttactacta aataccgcat ctatctctct ccttccagcc
    56521 attgtttcca ctcggcactc aattttttca ttgcttgagc ccgatgactg atcttgtttt
    56581 tttcttcgct cgataattct gctgctgttt gtttcttacc ttctgggata aataaaggat
    56641 catacccaaa gccattttcg ccagatggta tacgggctac tcgaccgggc cattccgctt
    56701 ctactacaag gctgtctttt ttgggtgccg cgaatactaa cgtacaatgg aattgtgctg
    56761 ttcttttttc atccggcaca tctgtcaatt catataataa tttggcgtta ttccccgcat
    56821 cacttttttg ttcccctgca aaacgtgcag aatagattcc tggcataccg cctaaagcat
    56881 ccactttcaa acctgaatca tctgctaaga ctggctgatc aagcaattgt gcaatcgttt
    56941 ctgcttttaa tcgggcattt tcttcaaatg tgctgccagt ttcttccaca tctggcaatt
    57001 caggatagtc aagtaatgtt tttacatgat atcccgcttc tttgaacata tttcgaaact
    57061 cttctgcttt tcctggattt cttgtcgcaa tgatgattgt ttttgtttct tctatccgct
    57121 catcattttg agcaaactct gttagcaaag catgtttttg ctctttgatc aaatcttcaa
    57181 tcgcgttttt tccaaaaaag agcatttcat tcaactgttc accatcaaac gttgcttctt
    57241 ctccagttcc ttgaatctcc acgaattttc cagattctgt cattacaaga ttcatgtcta
    57301 caagtgctgc ggaatcttct tggtaatcca aatctgtgac gcaagtccca tctggtaaga
    57361 ttcctacgct aactgcagca agatgttctt ttattggatc ttctgacaat tctttttctc
    57421 ttaaaagttt ttcaatggct aatttcaatg ccacaaatgc cccagtgata cttgctgttc
    57481 tagtaccgcc atccgcttgg atcacatcgc agtctacgat gatactacgt tctcctaatt
    57541 tttccaagtc tactactgca cgcaaggaac gaccaataag acgctggatt tccattgttc
    57601 taccagaaag tttccctttg ctgctttctc tacgatttct cgtactcgtt gctcgaggca
    57661 gcatactata ttctgctgtc acccatcctg ttcctgtttc tctcaaaaaa gggggaacag
    57721 aattttctat tgttgcagaa caaataactg ttgtatcacc aaaacggatc actaccgatc
    57781 cttctggata tttgaaaaca tttgtttgaa gctccagttt gcgaagctct tgggcttttc
    57841 tcccgtcatg acgcatcctt attttcctcc caattcgata tgttctacat ttaagtgtcc
    57901 gattccaagc cagtcttcag ctatttcctc gaaaagtttg gcagagccag ttgtataaaa
    57961 ctggcataat gtccgaccat tttgcggtga attgctcaaa ttgaaataat ctaacagcat
    58021 agatacttca cctactgttt ctgctccaga atcgatcagt tgaacatttt ctcccattac
    58081 attttgaatg atggggcgta ataatggata atgggtgcat cccaaaatca atgtatcgat
    58141 ttttttagtg gttaaaggag ctaatgtttc tgccacaatt tttttcgcca ccgatgaatg
    58201 gtattcatta ctttcgacaa ctgaaacaaa tttgggacaa gcaagacttg tcacagtcaa
    58261 ttctggtact ttctctttca gtgctttttc ataagcttga ctttttaccg taccaatcgt
    58321 accgataatg ccaacttgtt tattttgtgt tttttttact gccgctctag taccgggaag
    58381 gatcacaccg atgactggaa tagaaagagc agctttgatt tcttctaaag ccaccgcagt
    58441 tgcggtattg caggcgatca ccagcatctt gattccttgc tccaccagat aatccgtcat
    58501 ttcccaagta tactggatta cctgttccgc gggtctaggg ccatatgggc agcgtgctgt
    58561 gtctcctaca aataaaatat tttcattcgg taattgtttc agggcttctt ttactacagt
    58621 caagccgccg acacctgaat caataaatcc gatagggcga ttatctgtca atcgtatcat
    58681 cctttttttc aataaattct atcctcccta ttgtgtactt tttagcgtga attttcaagt
    58741 gctcttactt gcttaaaaca atcgaaatct ctttttttcg aatggaaaga ggaaaagcgg
    58801 ttgtgacttt agtttgccac aaccgctaaa agaatcatct attaataact gtaccgtctc
    58861 ttttccaagt aaccggaaag cagagaaagc gcgtaacata ccacgaagta cataagtgtc
    58921 atgatgatga acatcggaag cacataattg gtgttctgtc cataaataat acgtgcctga
    58981 tgagaaagtt caggtaaaga aatgattact gctaatgaag tatctttgat cagtgaaatc
    59041 aattggctca caattgccgg gatcattgat ttaaatgctt gcggtaacac gatcgttcgc
    59101 atcgattcta cataagtcag tcccgttgat aatcctgctt ccatctgtcc ttttggaaca
    59161 gcattgagtc cagctcggaa aatttccgac aacatagctg actcaaaaat cgttaatgct
    59221 gcgacagcgg accagaagat gttcatctga atgccgattt gaggtaaggc aaagtaagtg
    59281 aagaaaatga tcaataataa tggaagattc cgtataatat caatcactac accaaggatt
    59341 ttggaaaaga aagggatatt cgcaaaacga atcacacctg tcagaccacc gatcaagaaa
    59401 ctaaaaatga tcgaaaacaa tgaaacttca acagtaacct ttaatccttc caataaaaaa
    59461 cggatattca tccatgaaaa agcgccgcta aaatccatgt atttcccctc cttctatgaa
    59521 cgaaccgccc attttttctc aagataaacc attaagtaag ataacggtag cgtgataact
    59581 aagtaaaata acccaacgat gatatacgta tcgaaggtat tgaatgtttc actagcgatc
    59641 aagtctcctt gatacatcaa atctaaacca gctacgattg ctaaaataga tgagtttttt
    59701 acgaggttga taaattggtt gcctaatggc gggataacga ttttgaatgc ttgcggtaaa
    59761 acaatataac gcatgatttc tgaataggta aaaccagaag atagtcctgc ttctgtttga
    59821 ccttttggta cggtttgaat ccctgaacgt actgtttcag caataaaagc agatgtatag
    59881 atcgttaatc caatcgtacc tgcttggaat ccatctagat taaaccaata aatcggtacg
    59941 acaacataaa aaaacatcac gatgattaat aatggaatgt ttctaaaaaa ttctacatat
    60001 gcctttgcta aggcgctcac tactttattc tttgataatt ggaagattgt cattaacgtt
    60061 ccgataatca aactaaacac aagtgctaag acactcgaaa acaatgtgat cttgaacccg
    60121 tcgacaaaga ttggtccata agtttgtatc aattcgctca ttgcctctcc cccttactct
    60181 acttttcctt cagtttcatt tggaaaccat ttttgataga ttttatcgta tgtgccatct
    60241 gcatgcattt cctctagcgc ttggttaaca gctttcaaga agttttcttg ccctttgttg
    60301 atcgcaatcc cgtaaggctc attagtaaac gttccaccaa ctaactcata ctctggattt
    60361 tcatctgcaa tccctaacaa aatcgcatta tccgtagtca tcgcgtctcc ctgaccagat
    60421 tgtaaagcag taaatgcttc tgcatagttt tctaattcta aaatttttgc atctggtgca
    60481 tgctgtcgga tattcgcagc cgatgtagaa cctttgactg ctagaaccgt tgtagaagca
    60541 ttcaaatcat ctacactttt gatttggctt cctttcttta ccaacaaagc ttggccagca
    60601 tcgaaataga catctgaaaa gtcaacctgt ttttttcgtt catctgtgat cgtcatcgtt
    60661 gcaataattg catcgatatt tccgtttttc aataatggaa tccgagtttt agaagtgact
    60721 tcaacaaatt ctgtttttcc attgtcacca aggatctttt tagtgattgc ttttgcaata
    60781 tctacatcaa atccttgtac agttctgctc tcaatatcca tcattccaaa taatcgagta
    60841 tcatacttga caccccagat gatttcattg gtagatttgc ttcgctctaa aatatcttca
    60901 tttgccaacc catttccttt acatccggct agtgcaagaa aagcaatgcc taaaaggaaa
    60961 atcaggcgta ttttttttaa cctgcgcatc tttttcctcc tatcaatgat tgataacttt
    61021 actgataaat tgctgtgctc ggacttcatt tggattttcg aaaaagtctc tcacatttct
    61081 gctgtcttcc aatacttctc catcagccat gaagataaca cgatccgcca cttctttggc
    61141 aaagcccatt tcatgtgtca cgacaatcat tgacataccg tcatgagcca attttttcat
    61201 aacgtctaat acatcaccaa tcatttccgg atccaaagca gaagtaggtt catcaaacag
    61261 cagcatctca ggattcatcg ctaaacctct ggcgattgcc acccgttgct gttgtccccc
    61321 ggataacatg gaaggataag aatctttctt atctaacata ttgacagttt tcaaaaattt
    61381 ctccgcgttt ttgactgcag ttgcctggtc ttgcttcaac actttgattg gtgctaattt
    61441 gatgttttcc agaacagttt tatttgggta caaattgaaa tgttggaaaa ccatgccgat
    61501 gttttttcgg acttctgtca gttttgtctt tttatcatgc aagtcagtat cattaatcag
    61561 cagcttacct gaagagatcg tctctaatcc attgatacag cgaagcatcg tgctctttcc
    61621 tgaaccagaa ggaccaatga caacgacaac ttctcctttc tcgaattcga gattgatatt
    61681 ttttaatgcg tggaacttgc cataatattt atccacgtga tcaaatttaa tcattgccat
    61741 agaattacac tcccattatt atttagtaag atttctttta aagatgtata ataaaataca
    61801 ttatatctga tagtttagta atttgtaaag tttcttagaa cgtttattct cccataaata
    61861 tttcttccat ttctaatcta ttagttattt tatcctcttt ccttgttttt tccttaggaa
    61921 ctgttgtttc ttttcaggaa aaacggtaag atattaagtg ctcagactta caaatcgtaa
    61981 agaggtgtct tttttgaaaa atattatttt aacgggagat cgaccaactg ggaagctgca
    62041 tttagggcat tacgtcggtt ctctaaaaac ccgagtggct atgcaggcag atgaagacaa
    62101 ccaactgttt gtcatgattg ctgacatgca agcactgaca gataatgcta aaaatcctga
    62161 gaaggtttca tcaaatgtct tgcaagttgc tttagactat ttagccgtgg gattagatcc
    62221 tgcaaaatct actttattta tccaatcaca aattccggaa ttagctgaat taaccatgta
    62281 ttatttgaac ttagtcagcg taggacgcgt tcggcgcaat ccgactgtca aaacagaaat
    62341 cgaacaaaaa aaattcggtg aaagcgtgcc tacaggattc tttatctatc ctgtttctca
    62401 agcagcagat atcactgcat tcaaagcgaa tcttgtacct gttggtgagg atcaaaaacc
    62461 aatgctagag cagacacagg aaatcgtaca aagcttcaat catacatatg gtgaagtctt
    62521 ggtggaacca aaaggcgtat tcccaccaaa aggaatgggt agattacctg gaatcgatgg
    62581 aaatggcaaa atgagtaaat cgttaggaaa cggtatttat atctccgatc ctgccgatgt
    62641 cttacagaaa aaagtcatga gtatgtatac tgatccaaac cacatccatg tacaagatcc
    62701 tggacaagta gaagggaata tggtcttcac ctacttggat gtattcggaa cagataaaga
    62761 agcaattgaa gaaatgaaag ctcattaccg ccgcggcgga cttggtgatg taaagatcaa
    62821 acgatacctc attgatgtat tggaagctga atttgcaccg atccgtgcgc gccgagaaga
    62881 attggaaaaa gatccttcag ctgttatgga aatcttacgt aaaggtagtg aagaagctgc
    62941 taaagtagct gcacaaacac tttctgaagt aaaatcagca atgggaatca attacttcca
    63001 ttaattcatt tactctaaaa aagcaggctg taaaggcctg tttttttatc tcgtctctgt
    63061 gctattcctt ttttaaaatc aaaaaaagag atgtgacgaa gttgtgtcac atcttttttt
    63121 caaatgtatg gtcttcaaaa gctacttgat cgttacttac tatattttcc ttcttagcga
    63181 atacttgcct ctaggttttc taccaacgct ttttcgactt tttccattgc tttattgatt
    63241 tcttcatctg tcaatgttgc ttctgggttg acgaatgtca ggctatacgc catggattta
    63301 tgtccttttt caatgttttc tccttgatag acatcaaata attggatatc tgttaaaaat
    63361 cttccggcag cagaacggat aacttctgtt aattcctgat ttgtcacagt ttcttttaca
    63421 agcaaagcga tgtcccggct gactgctggg aattttgtca ctgcttcgaa aacgatccct
    63481 ttttgagcag cttccactat agcagataaa tcaaactcag caacatatgt ttctggaata
    63541 tcataacttt ttgtaatcgt tggatgcact tgaccgacaa aaccaataaa tttttcgcca
    63601 aggtaaatcg cagcagttct tccaggatgc atttccttca tttctgtcac tgtttgataa
    63661 tggacatctt cagtgatgcc tagttgttca aataagtttt ctaaaagacc cttgatggtg
    63721 aaaaagtcta cattttgagc tttcgtctgc caatcttttt cttcccaaat accagaaata
    63781 gcgattgctg catgttttac ttcttgcggc agatgtgtac gtggatcatt ttcttggaag
    63841 aacacccgac caatttcata taaagcaatc tctgtatttt ttcgggcagt gttataactg
    63901 atatcatcta atagtccgct gatcaaattc attcgtaata cagaacgttc ttcgctcatt
    63961 ggccagtcca aacgtgtaat attactttca tttataacaa actgtcttga tttttcttct
    64021 gttgtcaatg cataactgat tgcttcgctc aatccgcttc cttcaaagat tgtacgaatt
    64081 ttacgagtag tttcttgttc ttttgacaag cttccagcaa ccgtttctcc acttggaagt
    64141 gtagatggca actggtcgta tccataaata cgagcaactt cttcgataat atctgcttcg
    64201 atttggatat cccagcgtct tggtggtact actacggaat aaacatactc cttttcttca
    64261 tagctaaatc caagtgcttc aaaaatctca tttacttctt taacgacaag agatgttcct
    64321 aaatattgat tgatgcgttc aagtgaaatc ttcactgata cgtcttctgc tttgatctct
    64381 gagcctttga ccgcgccttg tagaacttcc ccacccgcaa gagaaacgat cattgctgca
    64441 gcaacctcac tggcttctcc aacagtcgca tggttgattc ctttttcaaa acgtgcagag
    64501 gattcactac gcaaattaaa ttgttttgct gtacgacgaa tcgaaattgg atcaaataaa
    64561 gcagattcta gtgcaactgt tgttgtttca ttcgtgatct ctgagtctaa ccctcccatg
    64621 acaccagcta aagcaactgg ttctttgccg ttagtaatga cgagattgtc agttgtcaat
    64681 tcccgagatt ctccatctag tgttactaat gtttcatttt cttttgcacg gcggacaaag
    64741 atctcttttg atttcaattt gtcgtagtca aatgcatgta gtggttgtcc gaataaaagc
    64801 aaaatatagt tcgtcacatc tactacattg ttgattggac gaatgccttc gttcatcaaa
    64861 agattttgca gccattgagg acttggctgg attcttactc cttcaatgat tctgatttga
    64921 taagcaggaa ctgcttcttt atcttcaact tccacttgaa ttttatcgct agcaggacgt
    64981 gaggattcta ccagcttttc gtcatcgaat gtaggagtct gacgataaat tgccccaact
    65041 tcataagcta cgccacgcat tgacaatgca tccgcacgat tcggtgtgat agataattca
    65101 ataatcgaat catccatatc caaataagga aaaactggat cgccatttac agcttcttgt
    65161 ggcatataat agataccttc agcgtattct ttcggtataa cactatctga atagccaatt
    65221 tcttgtaatg agcaaatcat gccatttgat acttggccac gcatttttcc ttttttgatt
    65281 tttacattac cagcgatacg tgagttagga agtgcaacaa tcactttgat tccaaccttc
    65341 acattaggcg ctccacaaac gatttgagac agttcgtctt cgccaatatc gacttgacaa
    65401 atagaaaggt gatcagaatc tggatgtggt acgcattcct tgacttcacc gacaacgatt
    65461 tttttcaagc cttcttctgg aaccgttact ccctctactt cgattcctgt cacagacatc
    65521 ttatccgcta attcttttgg tgttacattc gataaatcta cataacgatt gagccattta
    65581 tatgaaacta acattttctt actccccctt gaactgactt aagaaacgta agtcattttg
    65641 atagaaatta cggatatcat tcactccata ccgcaacata gctacgcggt ctggtccaag
    65701 gccgaaagca aagcctgaat attcttctgg atcgattcct gacatcttca acacattcgg
    65761 gtgtaccatg ccagctccta aaatttcgat ccatccagtg tatttacata cgttacaacc
    65821 ggcaccacca catttgaaac agctgacatc tacttctact gatggttccg taaatgggaa
    65881 ataacttgga cgcaaacgaa tttcacgatc ttccccaaac atttttttca ttacgacttc
    65941 taatgttcct ttaaggtcgc ccattgtgat gtttttatca acaactagcc cttcaatttg
    66001 atggaactga tgactgtggg tcgcatcatc tgtatctctg cggaagactt tccctggcga
    66061 gatcattcgt agagcaccct tagagaaatc atgtttttcc attgtccgtg cttggactgg
    66121 tgaagtatgt gtccgaatca atatctcgtc tgaaatatag aaagtatctt gcatgtccct
    66181 tgctggatga tcttttggca gattcatccg ttcgaaattg taatgatcag attctacttc
    66241 atatccttct acgatctgat agcccatacc cacaaaaata tcttcaattt cttccatgat
    66301 ttgtgtcacg atatgacgtg taccatgttt tacttttcta ccaggtagtg tcacgtctat
    66361 tgtttctttt gccaaagctg catttaacgc ttcttcttct aatacttgtt tttttcgctc
    66421 gatctcttct gtcaaaagat ctcggatctc atttgcgaaa cttccgactt ttggtcgctc
    66481 ttctggactt agatctttca tcccacgtaa tacttctgtg atcggtcctt tttttcctaa
    66541 cgtttcaaca cgtatttgat ttaattcatt taaatcttgt gccgctgtga ttttgacgag
    66601 cgttgcttct ttcaagctct ctaattgtgc ttgtagagac atgtgcttgt tcctccttta
    66661 aattccaaat acaaaacaaa aagacctcat tcctgttaag gaacgaggtc ttcgcgttac
    66721 catcctaatt tgcggataaa tgacttacac cgcactctta cttcgttaac gacaattgcc
    66781 ggtctgattt tatcagacga actcggaaag tgaacttcat ttttcaaaca caggatctgc
    66841 tttcagtctg cgacagatct ccctgaactg gtttagccaa actactcttt ttcgtcatcg
    66901 ttctttactt attcgtatgg actatagttt acaagatttt ttttacaaaa tcaaccgcat
    66961 tcttcctctg tgatccattt ttcgctccaa acttgtattt gacgcatcgc tttttgcaag
    67021 tctgctcctt tttcagtcaa gagatattct gaacggctct tttcgctaca ggcaaagttt
    67081 cgagtgacta ttccttcttt ttctaattcc ttcaagcgtt cgactaatac tcgatcactg
    67141 accatcggga tttttgccgc aagctcaaca aagcgttgcg gaccgttttc gagtagtaca
    67201 tcgataatca atccgttcca tttttttcct aaaatagaga atgttttttc aaatttaggg
    67261 cataaaacga attctgtctg tgttagctcc atcatactca cctcttccca gagtatagca
    67321 taatccttac aaaacataag tcaagtttgc tcaattataa ttatttgtta atgtttataa
    67381 tttgtttcac tcgaagcaaa attaggaaaa cattttctac tggcttattc aaagcttctg
    67441 acattgcttg ttggtaaagt cttagctgtc cttgatattt ttggacgatt gcatctattt
    67501 ctgctggatc atccggatgt aaaataaaat ctgttttaaa atcatagata ttgagatgat
    67561 ctttttcttc taggtatcca tcgacgattc cgtggattaa tagttcatct tcttgatttg
    67621 gatagtcttg aaatacttcg tcagcaggaa gcagcatgga aaaaggttgt tctcgtttta
    67681 cgttttcttt gttggcaatc agctgttgac caagttctgt ttgaaagaac catataatag
    67741 aagaaacatc tacttttttc gcgacttttt cgtctactaa ccgtttcctt accaattcct
    67801 gtaatttttg atggatactc tctgtagttg gcatctctaa tggcagtaat tgtaacaaag
    67861 catgcgtagc agttccaaca gcagctgctg acacttgccg atctttttgc aaaaattttg
    67921 gttctgctag ttgttcttgc gtataacgaa attgacggga tgctgctttg ttctgactgc
    67981 tttccagagt caaacgtgat tcttgtgtat catctggatc ttcgaataat cgtttgattt
    68041 cagatacaga ttgataactt gtggtttgtg aagaagcttg ataaggatat tcatatgcca
    68101 gacgtttttg taacgaatct gctaataaag tttcatcttc tttcatctgc tgatctaagt
    68161 taaccagttc tttttcagca agcaactgtc tttgttcaat gatcgattgc tgattcatcc
    68221 atgaaataga aaactgtgca tttgaatgtt gaagaagaga agtcgaaatt tcttcctcta
    68281 agtatttctg catttcagga tgacggatca atccgtaacc aatccaattc atcaagctgc
    68341 ttctgccctt caaacgtagc gcaggatcaa aaactaactc ctcatgatca gctgcttcag
    68401 accacgtttg gatcatttgc tctttatttt tataggaacc gacaatgaaa agcttttgtt
    68461 ctgcccgagt caatcctaca tacaatttac gcatttcttc cgacaacaat ttgttttgct
    68521 ttgccaattt gatggcttga aacggtaacg tatcatataa cactcgtgtt tcaggatcca
    68581 tatagcgaat tcctgctcca agtttttctt caaaagcata ccgattgcgc aagtcttgta
    68641 agttgaactc ctttgtcata tctaacaaaa atacaactgg gaattccaag cctttacttg
    68701 catggatcgt cataacgcga acagcattat cttctattga aatgactggt tctgctaagt
    68761 ctttatcttt ttcttgcatt ttttcaatga aacgcacgaa ctggtataat cctctgaaag
    68821 aactttgctc gtaagctttg gcacgatcaa ccaatgcata aagattggct tgtctctgtg
    68881 cccctgctgg cagaccgacc acatactcta gatatcccgt ctcataatag atatcccata
    68941 acaagtcagt gatcgaagaa cggcgagcaa gttctcgcca atgctctagt tgcttgccaa
    69001 aatgttccag cttagctgct aattcatctt cgtttgatgc ttgataagca agcacagcat
    69061 catagtaagt atgtgcacgg ttagctaatc gaatgctggc taattctggt tcaatcagac
    69121 ccacgatcgg tgagcgcaat acagccgcaa gcggaatatc ttgataggga ttatcgatta
    69181 attgtagcag cgagatcatc gtgcgaattt ctgtcgcttg aaaatagttt tgagcatcat
    69241 tcatctctaa tggaatatcc aatgttttga aaatctctaa aatcgttaag ttgttcttct
    69301 ttgtaggtgt caagagaaca atgtctttgt actctatcgg acgacttttt tttgattttt
    69361 tatcataaat cataaaggag gaatcaatta attgacgaat ttttagtcct gtcataaaaa
    69421 gttcgccttc tgttttgtct tccagtatat catccgtcgg aatctcaatc tctgattctt
    69481 cctgttcttt ttcatagatc atgatttccg gctcaaactg ttcattctct ggaaagtctg
    69541 aaaatccttg gatcagtttg gctgcttcgt cataattgat ttgacccact gctggatcca
    69601 ttagttgttc aaaaataaga ttcgtaaaag aaaggacttc ttttctagag cggaagttct
    69661 cagccaaaac gattcgacgt ccgccttctt tctttgagaa attctcgtat ttcccgataa
    69721 ataaactagg atctgctaaa cggaaagaat agatggattg tttgacatcc ccaaccatga
    69781 acatatttcc ttttgtatca tcgggttctc ttagccagta taaaatggct tcttgtaatt
    69841 ggttcacgtc ttgatattca tctaccatta cttctttgaa tttttttcga taatgttttg
    69901 aagcttcact tggcagccat acatctttcg ttttttctgt gagaatctgc aacgctaaat
    69961 gttccagatc attgaaatcc agcacacctt tttcccgttt acgcatactg aaaccgtcca
    70021 tgaagctttg cgtgactttt gtcatttctt cgactaacgg tagtgctttg tccgttaatt
    70081 cttccatttg gcttggggaa acaggaaaat aacttttact tatctgctga atcagttttt
    70141 ttgctttatc cctcatgccc ttgacttcat tggaaatttc tttcaattct gctttccgac
    70201 tgctcttaaa agttgaaaaa gttagttgtt ccaaaccagc ataagcttct tctaaccgat
    70261 cttgcgagaa cgcttcatag atattcttga tctgctgttg ttctccagct acttgctcat
    70321 gcattttttc taatccttca ccttgtgcta actgagtcat ctgttcatat aactgtacac
    70381 attggtatat atctgccaaa actaaaggac ggatttgttt ttgatataat cgagatttcg
    70441 ctagcccctc aggcaaacga taattatcgc ttaactgttc tagccatttt tgggggtcag
    70501 ggttggcacg ggcaaactca taaagagaaa acaccagatt cgtcaagccg tcatctgaac
    70561 gatcattaga aaaattcatt gttaattgga aaaatcgttc atcattttct gcataaagtg
    70621 cttctctcag ctcgtcccac acatcctcct tcatcaagat cgtttctgtt tcatctgtta
    70681 acatgcgaaa gactggatca atatcaatta agtaataata acgtcgaata actgtcaggc
    70741 aaaaagcatg taaggttgag atattcgctg tgggcaataa aactaactgc ttagtaaaat
    70801 gctgtctacg tacagggtca ctttcgctat tgacggattc ttgtaatgcc tcttgaattc
    70861 tttctttcat ttctcttgcg gcagcttcag taaatgtcac aatcaataat tcatcgatat
    70921 caaaacccat ttttagtttt tcaatcactc ttcgaacaag cactgtagtt ttacctgatc
    70981 cggcagacgc agagactaat agattatctc cttgatcaaa aatcgcttgc cactgatcat
    71041 ctgtgaatcg ttcattttgc ggttttaaag gaatttgatt cactcttctt cactcctttt
    71101 caatattcta cgcagtgctt cttccttatc tattttctcc agacggtggt aattattttc
    71161 tttcagcatc acatcaaacg tacagatgct tctgaatgga caaaattcgc aggcaatccg
    71221 ctgtttatct ttataagctg gatttagttt gatttctccg gaagtaatcg catctccagc
    71281 taaccgcata ttttcccgat tatgcgccat gaatagttgc agttcttctt ccgtgaaaaa
    71341 tttgtcttta ctgaaactac ctttttggta ttcatctttc gcattttttt tcactggata
    71401 gatcagtgat tgttcttttg cttccagtga atgatctagt acttctaaaa gagcgggatc
    71461 atcgacaaaa acgccatcat aactaaattt tttcaatgta ttcttctcta catcatctgt
    71521 ctccgtcaat acaggattat gaacatgtaa ataatatgat cctgctggtt taacagccgc
    71581 ctttccagtc aaacgtaccg catccatcaa tgctacgtcc agatacgtca ataattgcat
    71641 agccatgcca taataagctt ctgtgacatc gaatgaacgt ccgctagatt tgtaatcaac
    71701 gacgcttagc caagtatctt cttgttcaga agctacatcg attcgatcga ttttccctcg
    71761 aacatggagt tttccaccat tactcaacgg taattccaga cctgtgatac cttttgctcc
    71821 agcaatctga ccaaatagaa tctctgtctg aagaggatgc atgcctgtat ttttgctctg
    71881 tttttgcaaa gcccatgtca ctttttgaat cgtctgtcct aactggtagc ggatatagtt
    71941 cattcttgca gaactatcca atatctcaaa ccgaagttct ccgaatactt cctgcagcac
    72001 tttttcagta aagtctctac gctgcgcatc ggacatattc actaaggata attggtttga
    72061 aaacagtagc ttgaagaaac gatccaatga ttcatgataa aaatcaccag ttgctgctgg
    72121 agttagacca taaacagttc gttctttcaa tttcaaacca aattgcatga agtatttgta
    72181 ttcacaatta taaaaattct ccatacgtga aattgaagta taaatctctt ttccataaag
    72241 ctcttccgcc attttttctg gcatcgaaac aggaacattt aaatgttcct gactttcaaa
    72301 aatctgtaaa gcaaaatttc gccatgacga attcagtact aattctttga gcttttgcca
    72361 gtgctttggt acaggttttt tttcatctaa agctaatcga taaatcctat tgactgtatt
    72421 gattccgctt ctgtaagtcc ctacataaca attagggtcg ctttcgatcg tcaaatgctc
    72481 ttttctctcg acgggaacag ataaatattc tgtgattcta cgcaaataag gagacatctt
    72541 cagcgaacca tctgtgtcat agctttgtgc ataactaaga tataatcgat ctgttccgga
    72601 aagaaaaaca agataggctt ggaaaggctc aaaagagata ctttcctttg atgggtcgaa
    72661 taaaaactgt ccatctggca aggcctgatt taatacttct cgttcttcac tggacaacaa
    72721 tccttttgtc tcttttcggt ctggaaacac ttgatcattc aaccctaatg caaaagtgac
    72781 ggcagcttga tttggtcgaa ctaattccaa acgattgatt cgcacttggt cgattgcggt
    72841 agggatttta ccataactta gattttctag accacttgta atgatttctt ggaacagtga
    72901 ccagtcaaaa gccgattcac cataaattac tacatattca tccaacagat caatcagcgc
    72961 tccccatgtc tgctcatggt ttcttgccgc ttctaagttt cctctgtcta cttcctgatt
    73021 acgccaaaac aataattgtt gctgtacgcc actttggatc aaaaattgat aaaaaacatt
    73081 tgcggcctct tgtcctgttt tgcttttctt tatttttttc aaaaatactg gtacagcttt
    73141 ctgaaataat cgtctaatcg tatttgactg ttcttccaaa tactgtacgt cttcaatctg
    73201 ttctgcttca aaatcatacg ccacaaactg ccagtctttt tcacgagtcc aataagttcc
    73261 ttgataattg taagcaagtg ctacattttc agtgatgtcc agttttttcc tgaattcatc
    73321 tcgctcttgt ttccattcat caagttcggt ttctgcttcc gtcgacagaa ataattcagt
    73381 tttgaaaaaa cgcataatat cacttagccg ataagaatag cggtcaagag cgaacagact
    73441 gttgatccat tcgatcagcg gatgattttc catcatttgt tcttcatcga tataaaaagg
    73501 aattgccatt tcttgaaaga tcggccgaag gatatttcca tataaagaca tattttttgt
    73561 cagcacttgg atatcacgat aacggtagtt ttcttcactg actagtcgtc tgatttcaac
    73621 agctaattgt cggacttctt cagttggatt ttcagcttcc cacaaatgga gatgctcttg
    73681 tccccctatt ttgtgtactg ccgctttctt ttggctagat gtctcttccc acattgtttg
    73741 cagcagttga agctctgtcg gacgagtctg ctctggtgca aatcggtcca ctaatatagg
    73801 gactttccgt tctcttgcac tttgaaaaag acggaaataa agctttccag tctcatgaaa
    73861 gagcgtaagt acttctggaa gatccgctgt ataaggacga tccagcaata aatcgacaac
    73921 caattgcccc ttttccatca ttgcctgcag taattgatac tcttgaccat tgattcgaga
    73981 aaaaccactg acaataaatt tgacgttgtt gaaatcttgt gtctgcatat aatttgctag
    74041 tatagatagt gcatcttcat ttgttagtgc acgttgagtc aattcgctgt cataagctga
    74101 aaaaatcagc ttcaagtctt tcattttaag ttgctggtct tctgcattag gtgaatcacc
    74161 aaataaaagc atcaggtctt ctggttgaat atttcctgta cgcaattcac tgtagagttc
    74221 ttgtaattga cgaataaacc ctcttttatt gatttctccg cgaaagattg ttaattcttc
    74281 ctcatttttt tctaaaatct gtcgcaagat cattgcagat cctgattctg ataattcatt
    74341 tcctgtaaga agagttgtct gttgcagcaa ataccaagcc agacgataaa aactaaatac
    74401 ttgaacgttt gttgtgctga aagttttttt tccgcttctt cttcgcatct ccgctaaaat
    74461 ttcttgttcc tgttcgaatt tgctgtagtt gggaacaagg aaaaatactt ggttacttgc
    74521 atcctggtcg agccaagcgg atgcttcgtc gatcaagact tgacggtgat cttttttccc
    74581 gtttccaaga ataaattgta aagacatgct tttcctcctt caacacatga tacggtgctc
    74641 ctttattata tcaaaaaata ctgaacattt gttctatatt cttcaaatta tatcctttta
    74701 aggttctgat atttctactt ttttaagtat acgcaaaaa
//
LOCUS       DAJSMK010000005        65407 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.005, whole genome shotgun sequence.
ACCESSION   DAJSMK010000005 DAJSMK010000000
VERSION     DAJSMK010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65407
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.005"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            380..3187
                     /locus_tag="ON488_000327"
     CDS             380..3187
                     /locus_tag="ON488_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCR3230547.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3378..3869
                     /locus_tag="ON488_000328"
     CDS             3378..3869
                     /locus_tag="ON488_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3230548.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3972..4961
                     /gene="manX"
                     /locus_tag="ON488_000329"
     CDS             3972..4961
                     /gene="manX"
                     /locus_tag="ON488_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HCR3230549.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4994..5797
                     /locus_tag="ON488_000330"
     CDS             4994..5797
                     /locus_tag="ON488_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HCR3230550.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5818..6732
                     /locus_tag="ON488_000331"
     CDS             5818..6732
                     /locus_tag="ON488_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HCR3230551.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6815..7189
                     /locus_tag="ON488_000332"
     CDS             6815..7189
                     /locus_tag="ON488_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HCR3230552.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7328..7573
                     /locus_tag="ON488_000333"
     CDS             7328..7573
                     /locus_tag="ON488_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCR3230553.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7745..8809
                     /locus_tag="ON488_000334"
     CDS             7745..8809
                     /locus_tag="ON488_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCR3230554.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9055..9480
                     /locus_tag="ON488_000335"
     CDS             9055..9480
                     /locus_tag="ON488_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCR3230555.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9473..9922
                     /gene="nusB"
                     /locus_tag="ON488_000336"
     CDS             9473..9922
                     /gene="nusB"
                     /locus_tag="ON488_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HCR3230556.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10019..10873
                     /locus_tag="ON488_000337"
     CDS             10019..10873
                     /locus_tag="ON488_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HCR3230557.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10874..12211
                     /locus_tag="ON488_000338"
     CDS             10874..12211
                     /locus_tag="ON488_000338"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HCR3230558.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12216..12440
                     /locus_tag="ON488_000339"
     CDS             12216..12440
                     /locus_tag="ON488_000339"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HCR3230559.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12442..13332
                     /locus_tag="ON488_000340"
     CDS             12442..13332
                     /locus_tag="ON488_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCR3230560.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13341..14159
                     /locus_tag="ON488_000341"
     CDS             13341..14159
                     /locus_tag="ON488_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HCR3230561.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14266..14715
                     /locus_tag="ON488_000342"
     CDS             14266..14715
                     /locus_tag="ON488_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCR3230562.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14733..16415
                     /gene="recN"
                     /locus_tag="ON488_000343"
     CDS             14733..16415
                     /gene="recN"
                     /locus_tag="ON488_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HCR3230563.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16470..16586)
                     /locus_tag="ON488_000344"
     CDS             complement(16470..16586)
                     /locus_tag="ON488_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HCR3230564.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16659..17615)
                     /locus_tag="ON488_000345"
     CDS             complement(16659..17615)
                     /locus_tag="ON488_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCR3230565.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17786..18154
                     /locus_tag="ON488_000346"
     CDS             17786..18154
                     /locus_tag="ON488_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HCR3230566.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18324..18755
                     /gene="mraZ"
                     /locus_tag="ON488_000347"
     CDS             18324..18755
                     /gene="mraZ"
                     /locus_tag="ON488_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HCR3230567.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18776..19735
                     /gene="rsmH"
                     /locus_tag="ON488_000348"
     CDS             18776..19735
                     /gene="rsmH"
                     /locus_tag="ON488_000348"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HCR3230568.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19740..20141
                     /gene="ftsL"
                     /locus_tag="ON488_000349"
     CDS             19740..20141
                     /gene="ftsL"
                     /locus_tag="ON488_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HCR3230569.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20142..22334
                     /locus_tag="ON488_000350"
     CDS             20142..22334
                     /locus_tag="ON488_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCR3230570.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSVYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22360..23322
                     /locus_tag="ON488_000351"
     CDS             22360..23322
                     /locus_tag="ON488_000351"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HCR3230571.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23336..24697
                     /locus_tag="ON488_000352"
     CDS             23336..24697
                     /locus_tag="ON488_000352"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HCR3230572.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24723..25811
                     /gene="murG"
                     /locus_tag="ON488_000353"
     CDS             24723..25811
                     /gene="murG"
                     /locus_tag="ON488_000353"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HCR3230573.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25826..27046
                     /locus_tag="ON488_000354"
     CDS             25826..27046
                     /locus_tag="ON488_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HCR3230574.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27202..28527
                     /gene="ftsA"
                     /locus_tag="ON488_000355"
     CDS             27202..28527
                     /gene="ftsA"
                     /locus_tag="ON488_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HCR3230575.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNIKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28550..29791
                     /gene="ftsZ"
                     /locus_tag="ON488_000356"
     CDS             28550..29791
                     /gene="ftsZ"
                     /locus_tag="ON488_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HCR3230576.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29808..30485
                     /locus_tag="ON488_000357"
     CDS             29808..30485
                     /locus_tag="ON488_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HCR3230577.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30499..31098
                     /locus_tag="ON488_000358"
     CDS             30499..31098
                     /locus_tag="ON488_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HCR3230578.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31113..31400
                     /locus_tag="ON488_000359"
     CDS             31113..31400
                     /locus_tag="ON488_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HCR3230579.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31449..32231
                     /locus_tag="ON488_000360"
     CDS             31449..32231
                     /locus_tag="ON488_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HCR3230580.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32252..32959
                     /locus_tag="ON488_000361"
     CDS             32252..32959
                     /locus_tag="ON488_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HCR3230581.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33221..36019
                     /gene="ileS"
                     /locus_tag="ON488_000362"
     CDS             33221..36019
                     /gene="ileS"
                     /locus_tag="ON488_000362"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HCR3230582.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKSYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36068..37594)
                     /locus_tag="ON488_000363"
     CDS             complement(36068..37594)
                     /locus_tag="ON488_000363"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HCR3230583.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37609..38256)
                     /locus_tag="ON488_000364"
     CDS             complement(37609..38256)
                     /locus_tag="ON488_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HCR3230584.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38440..38769)
                     /locus_tag="ON488_000365"
     CDS             complement(38440..38769)
                     /locus_tag="ON488_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HCR3230585.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38946..39674
                     /gene="sfsA"
                     /locus_tag="ON488_000366"
     CDS             38946..39674
                     /gene="sfsA"
                     /locus_tag="ON488_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HCR3230586.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39690..40703
                     /locus_tag="ON488_000367"
     CDS             39690..40703
                     /locus_tag="ON488_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR3230587.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40703..41980
                     /locus_tag="ON488_000368"
     CDS             40703..41980
                     /locus_tag="ON488_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCR3230588.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42043..44745
                     /locus_tag="ON488_000369"
     CDS             42043..44745
                     /locus_tag="ON488_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCR3230589.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44897..45214
                     /locus_tag="ON488_000370"
     CDS             44897..45214
                     /locus_tag="ON488_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3230590.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45244..45564
                     /locus_tag="ON488_000371"
     CDS             45244..45564
                     /locus_tag="ON488_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCR3230591.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45672..47132
                     /locus_tag="ON488_000372"
     CDS             45672..47132
                     /locus_tag="ON488_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3230592.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47200..47421
                     /locus_tag="ON488_000373"
     CDS             47200..47421
                     /locus_tag="ON488_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230593.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47452..47634
                     /locus_tag="ON488_000374"
     CDS             47452..47634
                     /locus_tag="ON488_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HCR3230594.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47634..48047
                     /locus_tag="ON488_000375"
     CDS             47634..48047
                     /locus_tag="ON488_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HCR3230595.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48170..49351
                     /locus_tag="ON488_000376"
     CDS             48170..49351
                     /locus_tag="ON488_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3230596.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49422..49586)
                     /locus_tag="ON488_000377"
     CDS             complement(49422..49586)
                     /locus_tag="ON488_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230597.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49740..49813
                     /locus_tag="ON488_000378"
     tRNA            49740..49813
                     /locus_tag="ON488_000378"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49774..49776,aa:Arg,seq:cct)
     gene            complement(49850..50050)
                     /locus_tag="ON488_000379"
     CDS             complement(49850..50050)
                     /locus_tag="ON488_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR3230598.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(50355..51587)
                     /locus_tag="ON488_000380"
     CDS             complement(50355..51587)
                     /locus_tag="ON488_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HCR3230599.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            51842..52411
                     /locus_tag="ON488_000381"
     CDS             51842..52411
                     /locus_tag="ON488_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3230600.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(52589..53029)
                     /locus_tag="ON488_000382"
     CDS             complement(52589..53029)
                     /locus_tag="ON488_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HCR3230601.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            53187..53951
                     /gene="map"
                     /locus_tag="ON488_000383"
     CDS             53187..53951
                     /gene="map"
                     /locus_tag="ON488_000383"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HCR3230602.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            53983..54906
                     /locus_tag="ON488_000384"
     CDS             53983..54906
                     /locus_tag="ON488_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HCR3230603.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            54982..56121
                     /locus_tag="ON488_000385"
     CDS             54982..56121
                     /locus_tag="ON488_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HCR3230604.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            56114..56914
                     /locus_tag="ON488_000386"
     CDS             56114..56914
                     /locus_tag="ON488_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR3230605.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            56914..57741
                     /locus_tag="ON488_000387"
     CDS             56914..57741
                     /locus_tag="ON488_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR3230606.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            57719..58453
                     /locus_tag="ON488_000388"
     CDS             57719..58453
                     /locus_tag="ON488_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR3230607.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            58553..59419
                     /gene="rfbA"
                     /locus_tag="ON488_000389"
     CDS             58553..59419
                     /gene="rfbA"
                     /locus_tag="ON488_000389"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HCR3230608.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            59433..60005
                     /gene="rfbC"
                     /locus_tag="ON488_000390"
     CDS             59433..60005
                     /gene="rfbC"
                     /locus_tag="ON488_000390"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HCR3230609.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            60027..61055
                     /gene="rfbB"
                     /locus_tag="ON488_000391"
     CDS             60027..61055
                     /gene="rfbB"
                     /locus_tag="ON488_000391"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HCR3230610.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            61153..62004
                     /gene="rfbD"
                     /locus_tag="ON488_000392"
     CDS             61153..62004
                     /gene="rfbD"
                     /locus_tag="ON488_000392"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HCR3230611.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            62038..64071
                     /locus_tag="ON488_000393"
     CDS             62038..64071
                     /locus_tag="ON488_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230612.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPAKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKIDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKEIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            64115..65395
                     /locus_tag="ON488_000394"
     CDS             64115..65395
                     /locus_tag="ON488_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HCR3230613.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIATLLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
BASE COUNT        21349 a        11112 c        14007 g        18939 t
ORIGIN      
        1 tttataaaaa taaaagttgt agtggaggct acgaagttta ctttgtcttt ttacacttaa
       61 tatttttttg ccaatttgga atcaggatgt tttgataact atcgttttca attgatggaa
      121 gctatattgt ttgctatcag tgaaataatt atatggtaaa cagtgttctt tttcttgttt
      181 ccattataaa aatcgtatcg ggatttttcg ttcttttaaa ttgaacattt ctatctatcc
      241 gcgtgttatc aacaaaacaa aatcaggtaa atagttgacg aaacagaaat aaatacatag
      301 tattatgttt tgaagcctaa gtacaatagt ctatagaaaa ggagcgatac cattggcaaa
      361 acgcattgac cgaatttata tgtatgtcaa agaaaaaacc gctcatttaa caaaggcaga
      421 atatgatcaa ggagtaacaa cacaggaaat tgctgaagtg ttagggattc agcgaacaaa
      481 tagcagtaaa gatctgaatc agctagtgcg cgaaggaaaa ctgataaaga cagacggacg
      541 accagtacgt tacatatatc aaacactcgt tacgcacgta aagccagtta caaaacatgt
      601 agtcagttac aaagaaacgc cggtctctga agaaaaaaat acactccaaa tagatactaa
      661 ggatatcttt gcaaaaatca ttggagctaa cggcagcatg aaaaattcag tggaacaggc
      721 aaaagctgcg attttgtatc cgccaagagg attaaattgt ttgattacag gacctaccgg
      781 atcaggaaag acttattttg cacacgcgat gtatcatttt gcaaaagcgc atcatgtaat
      841 agatgaggaa acggaactga ttgttttcaa ttgtgctgat tatgccaata accctgagct
      901 tttgatgagt catttatttg ggtacgcaaa aggtgctttt acaggcgcag atgaagaaaa
      961 aatggggatt atcgatcaag cggatggcgg tatgctgttt ttggatgaga ttcaccggtt
     1021 gccgcctgaa ggtcaagaaa tgatctttta ctttatggat catggaactt acagtcgtct
     1081 tggggaaaca acgaaatccc atgaagcaaa tgtacggatc gtaggtgcga ccacagaaga
     1141 cccaggttct tctctattag aaacttttgt tcggcgtatc ccaatcaata tcaaacttcc
     1201 ggcttttgaa aaacgtcctg caaatgagaa agtcgattta gtaaaaatca tgattgccca
     1261 cgaagcaaac cgcacgcagc gaaagatttc tttgacagaa gatgtagcaa aagcattgat
     1321 cggcagtgtg acctatggaa atataggaca attgaagtca aatatccagt tagtatgtgc
     1381 acgaggattt ctaaatcata tgcaatcacc cgaaatctcg atcacaatcg atgatttgac
     1441 agaagggatt cgtagcggat tgattcaatt agcaagcaac cgcagtgcaa tggcagagct
     1501 ttctaaaata ttggagccaa agataactgt agcaccaaat gatacgatca tgaaaatcca
     1561 atcggactcc tatgagttac cttataatct atatgatatc atcggagata aagcagcttt
     1621 actgaagtcg gatggtttgg atcaagaagc aatcaatcat ttcatttcta cagatatcaa
     1681 catccatctg aagtctttct ataaagacca tggtttttct tttaatgcag acagcaaatt
     1741 agcagaattt gtagatccga aaatcataga agtgaccaat cagatttatg taatggtcaa
     1801 aagatcttta ccatatgagt ttcagcaaaa ctttatttat gctatgagct tgcatatcag
     1861 ttcttttttg aaaaaaatca acttaggaga agaacggcat acgaatgata acatccgtga
     1921 gatggctttt gattttccag atgaatatgc tgttgcgaaa gaagtgcgta gttatatcga
     1981 aacgtatttt caagtggaga ttccagaaag tgaagactat tacttgaccg ttctactcgt
     2041 ctcgttacgg gcaaatcaag caagcggcag aatcggtgta gtcgttgcag ctcacggaaa
     2101 cagcacagca agcagtatgg tccaagttgt ccaacagttg ttagatgcag agaacgtacg
     2161 agcagtagac atgcctttgg atatggatcc gaaaacagca ttggaccgaa ttgaacgcaa
     2221 tgtacaagaa gtagatgaag gaagcggggt catactctta gtagatatgg ggtcccttgc
     2281 gtcgtttaat tcgcaaattc aaagagacac tggaattcca gtacgtactg ttgatatggt
     2341 aacaacttct ctagttttgg aaactgtacg aaaggtctca gtattaggga cagatctaga
     2401 tatgttgcat gaatcattga aaaattttcg aggttacgca gaaatatctt ctgtagaatc
     2461 tgttcaggaa gcaaaaccta ttcataagaa aaaagctgtt ttggctatct gcgcatctgg
     2521 cgaaggtaca gcacaaagaa tcaaagaatt gatcgaacga gcggtaaaca agcgtcaaga
     2581 aacagaatta gaagttctag ctttgtcgat tgtggaagtg aaagaagaac tgccagttat
     2641 ccaaaaagaa tatcagatca tagctactac tgggattact gatttgaata tccaagcccc
     2701 atttattcct ttagaacgtt ttattgatca aaatatcgaa gtcattttgg atcagttgct
     2761 gatggaatca gaattggagg aaactgaatt catctcccta gatgaagagt cagctaaaaa
     2821 tacgtgtgtt gagtttatct ctgataactt catctttatt aatggtagta agttaatcga
     2881 tccaatgtgg caattttcta cacaaatctc tcagacgacg ggaatcggcg atgaagaata
     2941 tggattcaaa atcaacctag tgatgcacac agcaggaatg atcgaacgta ttattcggaa
     3001 tgaaccattg actgtggaag aaaacgaatt gacaaataca acgaatgatc ctctttatag
     3061 ccaattggca gcctcagttg ttctgttgga agatcagata aaagtaaaag tgccgataga
     3121 agaaatgtat tatctgctac gtctagtcca taatcagtta gataaaaaag aatacactgt
     3181 gccatgaata cacaaaaacg atacactttt atagtgtatc gtttttgtgt attggttaag
     3241 aatcctttaa attcaattag tgtatcgtaa aaaagttggc acgctttttg cttatagtag
     3301 tgtgtgctag gaggtggttg ttcacacaga aatgataggg gtttctgtga agtagtgagg
     3361 aagaaggagt tttgcagatg gatattcgat tggcacgtat agatgatcgt ttaatccacg
     3421 ggcaagtcgc aacagtttgg tcgaagcaaa caggtgttga acgtatcatt gtgatcagcg
     3481 atgtagtcgc tcaagataaa ttgagaaagt ttctactaaa agaagctgca ccgccgggga
     3541 tcacagcaaa tgtaataacc gtgcagaaaa tgattcaaat ctatcatagt ggattattat
     3601 cacgagcaaa agtgatgctt ttattcacca atccccaaga tgttgaagcg gttgtccgct
     3661 gcggtgtaca gttgaagtcg ttgaatatcg gcggtatgag ttttactgaa ggcaaatcaa
     3721 tgattaccaa ttttgtttca gtaaatcaac aagatattga ttcctttcgt tacttgaaca
     3781 gtcaagaagt ggagttagag attcgaaaag tacctgctga caggaaaatc cttttgatgg
     3841 aactactagc gaaaatcaaa aaggtgtagc aagaatggtt gttggaaaag gtcaaataat
     3901 tctgttgtaa tggttagcaa ttattaatat ttttgaattt gttacaacaa aagtaaatag
     3961 gaggtataaa tatggtaggg attatcctag caagtcatgg acaatttgct gaaggaatct
     4021 tacaatccgg ttcaatgatc tttggcgaac aagaaaacgt caaagccgtg attttgaaac
     4081 caagtgaagg tccagatgac ttgagagcca aattggaaga agcggttgct tcttttgata
     4141 atcaagacga agtgttattc ttagttgatt tatggggcgg aacaccgttc aatcaatcaa
     4201 acacattatt cgaagagcac aaagataaat gggcaatcgt cagcggtttg aatttaccaa
     4261 tgttgattga agcctacgca tcacgctttt caatggaatc tgctcatgaa attgcagcac
     4321 acatcattga aacagcaaaa gacggtgtaa aagtaaaacc ggaagaatta gaaccggcag
     4381 aagcaccgaa agcagcagtt gaagacgcac aacctaaagg agcacttcca gaaggaactg
     4441 tggtcggaga cggaaaaatc aaatatgtat tagcacgtgt tgactcacgt ctgttacatg
     4501 gacaagttgc gacagcttgg acaaaagcag tgcaaccaaa ccgtattatc gttgtttcag
     4561 atgcagtatc aaaggatgat ctgcgtaaga gactaatcga acaagctgct cctccaggtg
     4621 taaaagcaaa tgttattcct attagcaaaa tgatcgaagt agcaaaagac cctcgttttg
     4681 gaaataccaa agcattgctt ttatttgaaa atcctgaaga cgtattgaca gctgttgaag
     4741 gtggcgtaga catcaaagaa ttaaatgttg ggtcaatggc gcattcggtc ggtaaagtcg
     4801 ttgtaagtaa agtattgtct atgggacaag aagacgttga agcgtttgag aagcttgaac
     4861 aaaaaggtgt gaaattcgat gtacgtaaag tacctaatga ttcacgcgat aacatggatg
     4921 atattttgaa aaaagcaaaa gctgaattag caaaagcgta ataaataata ttaaaattta
     4981 taggaggctt atcatgtcta ttatttcaat aattttagtc gtattagttg cctttctagc
     5041 tggtatggaa ggtattcttg atgaatttca atttcatcaa ccactagtgg catgtacatt
     5101 gatcggttta gttaccggta acctcgaagc tggtatcgta cttggcggta cgcttcagat
     5161 gatcgcttta ggttgggcaa atatcggtgc cgctgtagca ccagatgctg cattagcatc
     5221 agtagcatca gcaattattt tagttttagg tggacaaggt gttaaaggtg ttccttctgc
     5281 gatcgcgatt gccgttcctt tggctgttgc agggttgttc ttaacaatga tcgtacgtac
     5341 aatcgctgtt ccaatcgttc atttgatgga tgcggctgct gaagaaggaa acatccgtaa
     5401 ggttgaaatg tggcacatca ttgctgtatg tttacaaggg gttcgtatcg cggtcccagc
     5461 agcagcgttg ctatttatcc cagcacaaac tgtgcaatca ttccttgaat caatgccagc
     5521 atggttaaca gatggtatgg ctatcggtgg gggaatggtc gtagctgtag gttacgcttt
     5581 ggtaatcaac atgatggcta caaaagaagt atggccattc ttcgttattg gtttcgttgt
     5641 agctgcaatt tctcaattaa cattgattgc tctaggtgct ttaggtgttg cattagctct
     5701 tatttacttg aacctttcta aaatgggtgg ttcatcaaat aatggaggcg gaagcaactc
     5761 tggtgaccct ttaggcgaca ttttgaatga ctattaatct tgaaggagga aaataaaatg
     5821 gcagaagaaa aaatcaaatt atcaaaaaaa gatcgtttag ctgttgcgtg gcgctctacc
     5881 ttcattcaag gttcatggaa ctacgaacgt atgcaaaacg gtggctgggc attttctatg
     5941 attccagcaa tcaaaaaatt atacaaaaca aaagaagaac gttctgcagc attaaaacgt
     6001 cacttggaat tctttaatac acacccatac attgcttctc caattttagg ggttacattg
     6061 gctctggaag aagaacgtgc gaatggcgcg cctgttgatg atgtagcgat tcaaggggtt
     6121 aaagtaggta tgatgggtcc tttagctggt gttggtgacc cagtgttctg gtttacagta
     6181 cgtccaatgc taggtgcact aggtgcttca ttagctatgg gaggaaatat ccttggacca
     6241 atcatcttct tcttaggttg gaacattatt cgttgggcat tcatgtggta tacacaagaa
     6301 tttggctaca aagctggttc taaaattact gatgaccttt ctggcggatt gttacaagac
     6361 gtaacaaaag gtgcttcaat tttagggatg ttcgtattag ctgcccttgt acaaagatgg
     6421 gtatcaatca aattcttacc agttgtatca actgtaaaat tagataaagg tgcttacatc
     6481 gaatgggata aattgccttc aggtggtgaa ggaatcaaga gtgcatttga acaagttaat
     6541 aatggcttag ccctttctcc tgaaaaggta acaacattac aagacaactt agaccaattg
     6601 attcctggtt tagctgcatt aggattaaca ttgttatgta tgtggttgct taagaaaaag
     6661 gtttctccaa tcgttatcat ccttggttta ttcgtagtcg gtgttgttgg acacgtcatc
     6721 ggacttttat aatccataaa aatatagctc gggcgttgtc ccgagctttt tttatatagt
     6781 atactgttca taaacaaata tctggaggga gaaaatggtt caatcaatca atacaaaagt
     6841 agacttggta attgatgcta cttcgtttac gggtctgaca gattacgggc aaatcatgat
     6901 aggtgataat ggttttgagt tttaccatgc gcgagataga cgcaaatata tccaaattcc
     6961 atgggaagaa gtggattatg tactagcatc agtcatgcta aagggaaaat ggattcctcg
     7021 atatgccatt caaacgaaaa aaaatggtac atacacattt tcttccaaag aacctaaaaa
     7081 agtgcttcgt gcgatcagag aatatgtaga tgaagataga atggtacaat cattgagttt
     7141 ctttgatgta gtgaaacgtg gtattcgtag tatgtttaaa cgcaagtaaa aaataaagaa
     7201 aacttctaag aggaggtttt ctttattttt ttactttgca gaagaaaata tgaaatagca
     7261 aaaccaatta tttgtcccct ttaaatccca tatgctaaaa ttgattagca aagaaggagg
     7321 ttatattatg agttggttat ggacattgat tgttggagcc gtgatcggag caattgcagg
     7381 tgcgatcacc agtaaaggaa attcgatggg ctgtgtaacg aatatcattg ctggactagt
     7441 cggttcaagt attggacaag cgattttcgg cgaatgggga ccaaaagctg caggtatggc
     7501 acttattcca tctattttag gcgcagtgat tttggtagca gttgtctcat ttttctttgg
     7561 aaaacgatca taagttttta caaaatagta aactaaaagg agttgcagcg agactgtgac
     7621 tcctttttgg ctttatttat ttaaaataaa aagaagtttt ccggaaattt ttatttaact
     7681 gtcgtgtacg aagaaaagtt tgctataatg gaaaaaagcg tgcaaagaaa gagggagttt
     7741 cattatgatg ctacgtgtag aaaaattgcg caaaaaaatg caagaagaaa atttggattc
     7801 atttttggtt accagtccgt acaatcttcg ttacttaacg aactttacag gtacgacagg
     7861 attagctgtt attactttgg aaaaagcatt ttttattact gattttcgtt ataccgagca
     7921 ggcggcagcg caggctcaag ggtttgaaat tattaaaaat gtcggaccta tttttgatga
     7981 ggtagcaaac ttagtacgca aagaagaact gcactcatta gcttttgagg aaacaacagt
     8041 ctcattttta gaatattcgg ttttagaaga aatcatcgat gcggaattag tacctgtttc
     8101 acagatgatc gaagaactca gagaagtgaa agatgaagaa gaaatcgcta ttatcgaaaa
     8161 agcatgtcat attgcggata tggcatatga tcacatcctg aaaatgatcc aaccgggcat
     8221 gactgagatt gaagtcgcaa atcaactaga cttttatatg cgttctcttg gcgcttcagg
     8281 tgtttctttt gatacgatcg ttgctagcgg attgcgttcg gctatgccgc atggtgtagc
     8341 aagcaaaaaa atcatcgaac aaggtgactt gatcacattg gactttggtt gctattacga
     8401 agggtacgtt tccgatatga cacgtacatt cgctattggt gatcctgggg aaaaattaaa
     8461 agaaatttat caaatagtct tagatgctca attagcagtt attgatgctg caaaaccagg
     8521 aatgactggt gtccaattag atgcagttgc tagagattat atttcaaaac atggttacgg
     8581 ggaagcattt ggacattcta caggacatgg gatcggttta gagatccacg aaggaccaaa
     8641 cgtttcttct cgtgcagaaa agcaatttgt accaggaaat gtgatcactg atgaaccagg
     8701 gatctactta ccaggaatcg gtggagtacg tattgaggat gacttgttga tcacagaaga
     8761 tggaaatcgt gtgttgactc gttcaccaaa agaattgatc atcttatagt ttcatcaata
     8821 gaagaagtaa gcgtaaaaat cagtgttcac agactttgtt atagaaaatc actcgattta
     8881 atgatacact atagaagaac ttttaagctg taagagataa taaagttggg tgttttctcc
     8941 aattcatagc agtttgcagc tgatcggcgg cagttttctt accacgtgat cactatgccg
     9001 catcatagag aattcggatg tatctcgtgc ttaggcaaag ggaggaataa ataaatggca
     9061 gatgaaaaaa atttgatttt aaacgcaaac caagatttag gagagatcgt gatcgctcct
     9121 gaagtcatcg aagtaattat cgggattgca gcttctaaag tagaaggcgt atacggaatg
     9181 cgcggaactt ttgccagcaa tgtcactgaa ttattaggac gtgcagctca cggaaaaggt
     9241 gtttacttag caaacgagga agatggcttg aaagtagatc tttactgtta tctagaatat
     9301 ggtgtttcag ttcctaaagt agcaatggaa atgcaggaac gggtcagcca gcaagtcctt
     9361 ttcatgacgg atatcgattt atctgaagtc aatatccatg tagtagctgt tgttcctgaa
     9421 aaattagaac aaccaacaat cgaagaactt tttgaagacg aagaggaaga gaatgaataa
     9481 agaattatca agacacgaga ttcgggaaat ggcattgcag gctttatttc cattagactt
     9541 caatgcagac ctaacaaaag aagatgcgat tttcaacgca atcgaattag accaccgcga
     9601 catgatcaac gaagatgaat cagagtttgt tcctgtttat cttgatacgc tagttggcgg
     9661 tgtctgtgca aaaaaagatg aattggataa agtgattgaa aaacatttaa aaaacaattg
     9721 gcacatcaat cggatctcaa aaatggattt ggtgatcttg cgtatcgcga tttttgaaat
     9781 gacttatgtg acagatgtac cagcggctgt tgctttaaat gaagcaatcg agttggcaaa
     9841 aacatttagt gatgaccgtt cacgtaaatt cgtcaacggt gttttatcca atgtattgaa
     9901 agaattagaa gctggggcgt aagtcctagc ttttttctat gaatcatcat aaacctgtta
     9961 taaatcggga aaattctatg gtagaatgaa aacacaaaaa atatctggga gtggttagat
    10021 ggcagaattg attaacggaa aagaattagc tgaaaaaatg caggcagaga ttgctgaaaa
    10081 aatccaaaaa ttgaaagata atggtatcca tcccggatta gtcgttttat tggtagggga
    10141 aaatccagcc agccaaatct atgtaagaaa taaagaacgt gtagcaaaag aaatcggaat
    10201 ccattcattg gtagagcgtt atcctgagac gatttctgaa gacgaactac ttgcagaaat
    10261 tgaaaaatac aatcaagatc ctagttttca tggtatattg gtccaattac cattgccaaa
    10321 gcatatagat gaagaaaaga tcctgttagc tatccgccct gaaaaagacg tagacggttt
    10381 tcatccgatg aatttaggca gactccttgc gggtaaaccg gacaagattc cttgtactcc
    10441 atacggcatc atgaaaatgt ttgaagctta ttctatcgat ccggcgggta aacgagcagt
    10501 agttatcgga cgaagcaata tcgtcggtaa accgatggct cagctactct tgatggcaga
    10561 tgcaactgtt actgttgctc attctaaaac cgaaaatctg gctgaactgg cacaagaagc
    10621 agatatttta gtcgtagcaa taggacgtgg acattttgtc acaaaagaat tcgtaaaacc
    10681 aggtgctgta gtgatagatg tagggatgaa tcgtgatgct aacggtaagc tgatcggtga
    10741 tgtgaaattt gatgaagtgg agcctattgc aggctggatc actcctgtgc caaagggtgt
    10801 agggccaatg actatcacga tgctgatgta tcaaaccgta aaatctgccg aagcttttgg
    10861 agcaggtgaa tagatggcac aagaatattt aactgtcact acattaacga agtatttgaa
    10921 aagaaaattt gatgccgatc cttatttaga acgcgtatat ttaacaggcg aaatatcgaa
    10981 tttccgttta cgtgccaatg cccatcaata tttcagctta aaagatgacc atgcaaaaat
    11041 atctgctatt atgttcaaag gagcattcca aaaattacga ttccagccaa aagaaggaat
    11101 gaaagtcctt gtcgttgggc gtatttcatt atatgaagcg ggaggttctt atcaaatcta
    11161 tgtagagcac atggagcctg atggaatagg tgctttatat caagaattgg aagaacgaaa
    11221 agaaaagctg atgaaggaag gcctttttca agggcctaaa aaaatgctgc cacgtttccc
    11281 aaagcgaatc gcggtcctta ccagtccaag cggagcggtt atccgcgata tcatcacgac
    11341 ggtgaaaaga agatatccaa ttgtccaatt ggttttgttc ccaacagttg tacaaggaaa
    11401 ccaagcagcg gacaatgttg tcaggaatat ccagagagta gaagagatgg gcaatttcga
    11461 tacaatgatc atcggtcgtg ggggtggttc gattgaggat ttatggccgt ttaatgaaga
    11521 gcgggttgct cgggcgattt atcaagctaa tacgccggtg atttcatctg taggacatga
    11581 aacagatacc acgatcgctg atttagtagc agatgttcgg gctgccactc caacagcagc
    11641 tgcagaatta gctgttcctg ttttgtcaga agagttgatg cgcattcaag aacggcaagc
    11701 tagattgcag caggcgtttg tacgccagat ccagcgcaaa caagaacggt tcgagcgtgc
    11761 tcgacgttcc tatgtatttc ggcagcctga aagattgtat gaaggtcaga ccatcaaatt
    11821 agaccagttg aaacagcgat tatatcaagc tacacagcaa atttatcatg cgaaagaaaa
    11881 acaaacgatc gcattaagcc accaattgga acaagtggct ccgctttatc gagttaaagc
    11941 agctcgccaa gaaactgctt atctagaaaa acgcttagaa gagaaaatcc aacaatatat
    12001 gaaacaacag cagcagcgtt ttgctcaagc tgttcaatct cttgatttgt tgagtccatt
    12061 gaaaatcatg ggaagaggct acagctatac gacgttaaat gatcaagtag taaaaagtgt
    12121 caccgagatt catcaagggg atttgctgac gatccattat caagatggaa tcgttaaagg
    12181 acaagtacaa gagatagaca aaggagaata aaaatatgga aaatccaact tttgaagagt
    12241 cactgcaaga attagaaaaa attgtcatgc agttagaaca aggagacgtt ccattagaat
    12301 cagctctaga ttcgtttaaa cgaggaatgg aattaagcaa acattgccaa gatacattag
    12361 ctaaagcaga agagaccttg acgaaaatga tgacagaatc aaatgaagaa gttgattttg
    12421 acggaaacga ggaaagctga gatgagatta actgactttt cagctattca tctacctgct
    12481 gtagaaaaag aaatcttgtc ttttttagat gagcatacaa cggatagagg actctatgat
    12541 gcgatgagtt attcagtgaa agcaggcggg aaaagaatac gtcccttatt acttttaacg
    12601 gccgttgctt cctttgatga gcctattgat gttcccgtct atcaagtagc agctgcttta
    12661 gaaatggtgc atacgtattc cttgatccac gatgatttgc ctgcgatgga caatgatgat
    12721 cttcgtagag gaaaacctac caatcataaa gtattcggcg aagcattagc tatattggcc
    12781 ggagatggtt tgcttacagg agcattccag ctaatcagta tggcacactt aggtaattct
    12841 cctaagcttc tgctgcttca gcaattagct gtttgtgcgg gatcacaagg tatggttgct
    12901 gggcaagctg cagatatcga gggcgaatcg aaaaagcttt ctttagaaga attagcattt
    12961 attcatgaaa gaaagacagg gcatttgatt cgttatgcct tgctggctgg tggcatatta
    13021 gcgaagcaac ctgaagaaat cttattgcta cttcaacgat tagccgaaca tttaggttta
    13081 gcttttcaga taagagatga tctactcgat gtgattggta caacgaaaac attagggaaa
    13141 acagctggta aagatgaacg tatggaaaaa aatacttacc cgcgtttatt aggcctagaa
    13201 aagacacgtg aggcgttgga gattgagctg ttatccgcca acaagatcat agacaaatta
    13261 gaagaggacg ttttttcttt tgatggcggg ctgatgcgcc agatgatcaa gcaatttgat
    13321 gtggagaaat gagggaaaga atggaaaaag aacgcgtaga tgtattagcg gtcaaacaag
    13381 gattatttga aacaagagaa caagccaaac gttcagtgat ggctggtttg atttacaacg
    13441 aaaaaaacga gcggtttgat aaaccgggag aaaaaattcc agtgagtagt gaattaagag
    13501 tcaaaggtaa aaaacttcct tatgtttctc gagggggatt aaaattagaa aaagcactca
    13561 aagcatttga tctatctgtt gaaggaaaaa cattgttaga tattggtgca tccactggcg
    13621 gatttactga tgcagctttg caaaatggcg caaaaatgag ttatgcttta gacgttggct
    13681 acaatcagct agcttggaaa ataagacaag atcctagagt cgtcgtaatg gaaagagtga
    13741 attttcgtta tgcaaaaccc gaagacttta ccttaggaat tccagaagtt gctgttatcg
    13801 atgtttcttt tatttcacta aaactgatgc tgcctccatt acatgctatt ttaaaagaag
    13861 agggagaagt gattgcttta atcaaacccc aattcgaagc aggcagagaa gctgtaggga
    13921 aaaacggaat tgttcgtgac cctcagaccc atcaaaaagt tttagaagac attttgtcat
    13981 ttgcggcaca aggtggatat gatgtgctgg aattaagtta ttctccgatc acggggggag
    14041 aaggaaatat cgagttcttg gctcacttga ggaaagtacc cgaaagcgga acaatcaatt
    14101 cagctattaa tatggcagaa gtggtttcaa atgcacacga acagtttgac cataaataaa
    14161 ttgtaactgt gaaaatcaag tgagaagtat gcggattctt ctttattata ccaaggaaat
    14221 aagctatcat tgattaagaa gaatatgcta aggagcgaag acgtaatgag aaaaaaagat
    14281 cggcatcgtt tgattactcg attgttgagt gagcaagata tccgaaagca ggaagaattt
    14341 gttgaaatcc tgaaaagcaa aggaatatct gttactcaag ctacgatttc cagagatata
    14401 aaggaactga aactgatcaa ggtaccggct tcagatggcg gctaccgtta tagcatacca
    14461 gctgaaacaa acgaagatgt aaatactaaa ttggaaaaac tattaaaaga cgctttcgtg
    14521 gcagttgacc aaatggaaaa atttgttatt ttgaaaacat tgccgggaaa tgcttcggca
    14581 gcagcaaatt tgattgataa acgttacaag aaagaattat tttcgattat caatgatgac
    14641 gataatgttt tgatgattac acgaactgaa gaccaggcag ttttattgaa gaaagacttc
    14701 ctgcattacc tttaagttga ggagcgaatg tgatgctaca agaaatcagt attactaact
    14761 ttgcgattat tccggaattg cggctttctt ttcacgaagg aatgaccgcg ctgaccggag
    14821 agactggtgc gggtaaatcc attattatcg atgctttagg tctgttagca ggaggaagag
    14881 gttcaagcga ttatatacgt caaggagcag aaaaatgtgt gcttgaaggg ttgtttgaac
    14941 taccaaaaca agaaggattc tctgaactga tggttgaatt agggatcgaa acagatgagg
    15001 acaatctgat tgttcgacgg gatatgtcct taactggaaa aaatgtttgt cgagtgaatg
    15061 gtcatattat cacattagct aatctgagaa gaatcggcag ttatttagta gatatccaag
    15121 gacaaaacga acatcaggaa ctgctccagc ctgaatcaca tcttgcttta ttggatcgtt
    15181 ttggagatgt agctttccaa cagaagaaaa agagttatca gcaagaatat atctcttatc
    15241 gtgagctgga aaaaagggta cgaaaagtgc agcaaaatga aaaatcctat gttcagagaa
    15301 tagatatgct ccatttccag caagaagaaa tagctgctgc tgatttgcaa gtcggagaag
    15361 aagagaaatt aaaagaagaa agagaaaaac ttagcaatta tcaaaaaatt gctgatggat
    15421 tagctgcagg ttacggagca ctgacgaata atgaacaaaa cagtgtagat ggtgttggct
    15481 tggccgtttc agaactgcaa gggatcgccc atctagatgt ggagtatgaa gcaatttatg
    15541 aaaatatcca aagtgcttac tatttgctgc aagatgcaat cggcgatatg agtcgtcaga
    15601 ttgatttatt ggagttagat gagagtcgtt tagaagaagt tacgcaacgt ttagaattaa
    15661 tccgacagtt gaaacgtaaa tacggcgaat ccattgagtc aatattggct tactatgacg
    15721 aaatcaccga agagctagct tcttctgatt tttcagaagg tcaattggac aaaatgaaag
    15781 aggaactaga gcaaaaagag cttctacttc agcaacaagc cgcagatctt catgaagcgc
    15841 gtaaaaaaat cgcaaaagaa ttggaaaaat ccattctgca tgaattgaaa agtctgtata
    15901 tggaaaacac tgagtttgag gtacgtttct taaaagaaga aaatagacaa ttgaatcatg
    15961 atggatttga ccaaatcgaa ttttacatta cgaccaatcc aggagagcca ctgaagcctt
    16021 tggtgaaagt cgcttctggt ggcgaactgt ctcggatgtt gcttgctttg aaaactattt
    16081 tttcttctga gcaaggtgtg acaagtatta tttttgatga agtggataca ggtgtgagcg
    16141 gaagagttgc acaggccatc gcagataaaa tttctcaaat atcgaaatac tctcaagttt
    16201 tgtgcatcac tcatctgcct caagttgctg cagtcgccga ctatcaatat tatattgtga
    16261 aagcagtgat tgatggacgt acgcaaactt ctgtttcaga gttgaaaaca aaagaaagag
    16321 aagaagaaat tgcacgtatg ctggctggaa gtgagattac aaaactcaca ctcgaacatg
    16381 caaaagaact attgaaactc gcaaaaagga cctgagccac ctcgcagtgg ttcaggtcct
    16441 tttcagcagc tgatagctat attttatttt tacatgacac tcattacagc agtcaataca
    16501 acagatccaa tcgttaaaat cagcattgtc caaatgacaa attttgttac tttagcaaaa
    16561 gtacttgttt gttttttttc acgcattgtt ttcaacctcg tcattaatta gttgattcaa
    16621 gtgtacaatc ttttttccat ttccacaaga gggctttttt ataaaaactt cccttttttt
    16681 aaataatagg tagttacgat acaaataaat aatgttaata gaactagcca tataaaggca
    16741 tcatcccttt cagcaatagg taacttaatg ttcattccat agatactgcc gacgattgtc
    16801 ggtatagtta aaataatcgt taaagaagtt aaaattttca taatattatt cagattattc
    16861 gatacgattg ctgaaaaagt ctgattcatt tgttctacta gttttaattg aatgcgagaa
    16921 gtagtcattg cctgctctgt ttccaccaat acatcacgta aatgattttt caaagcatga
    16981 ttttcttgga aaagtttatt ttgcgctagt tctttcaatg catctaaatt agcagaagtc
    17041 gcttctctga aataaacgag gcttttttgg atatccatga tttgataaag ttgtttgttt
    17101 tcagtggata cttgaagttt ggcttccaaa gtatcgcatt gagattgaag cgtagctaaa
    17161 taactgttgt aagagagtgt gacctgccaa atgaattgaa agaagatatt gagattaggc
    17221 gaaatatcac tttttggaaa ggtctggcta aagactttct ttaaaaacag tggttcatga
    17281 ttcgtaattg tgataagctt ctttttgggc gtcaaaataa tagagagcgg gtatgtatcc
    17341 acttgaaaat aaccgctagg acttgtttta gcaaaaggat attgtaacaa taataacgct
    17401 ggctttgtca actttgattg attgaattct tctgtacggg aattttctgc atcgtccaat
    17461 atggaagtga tgtaatctga cggaatttca aattgatgtg tcagctgatg aatctcttct
    17521 tgattaggac gttctacaca ataccagatc gtttggtcag tttcctttcc ggtattacgc
    17581 agtttctcat tatctaatgt aaaatatttg atcatgattt tcctcctgtt gcctgtttct
    17641 tttattataa cggataggga attggaatac atggaatgtg tttgtaagat atagaatata
    17701 actgcataaa tttaaataaa atgaaacagt tgtgtaaagt atatacagta tacttgaagc
    17761 aacgataaaa aaggagttta cgttcatggg cacattcaca ccacttatct tgttttggta
    17821 tatttacccg gtaatcgttt tgtttggttg ccaatttctt gtaaaattat tttcgttaaa
    17881 tcgtcgtttt aaaataaaag cccctgattt ggcgattcct tttttgtggg gcggtatgca
    17941 tgcattgtct agaaatacag ggacaatttc tatcttaccg tttttcttta tttctgtttt
    18001 gctaatggga atttgtattg ctgttttcca agcatattat tatgaagaaa ttatttatcc
    18061 gcgttatttc aagatgactt ggcgtttggt ttttctgttg acaatcgtct tgtacgctgt
    18121 cttgatcatt gtgaacatac tttcttacct atgaaaaaaa tagaaaagct gtaaaaagtc
    18181 ttttaaaagg ctttttgcag cttgattttt aaaaaaatgt ttatgaataa aaaaagttgt
    18241 tcccggattt cccagaaaag gtggtagaaa gtgggggatt gtggtagact aattttagtt
    18301 agtggaggaa tggggggctt tcaatgttga tgggtgaatt ccaacataat attgatgcaa
    18361 aaggacgttt aatcgtgccc tcaaaacttc gtgaagaact tggcgaaaag tttgttctga
    18421 cacgcggatt ggatggctgt cttttcggct atccgatgag cgaatgggaa aatctggaag
    18481 ctaaactgaa cgaaatgccg ttggctaaaa aagacgcacg tacttttgtg cgattcttct
    18541 attcggctgc cactgaatgc gaacttgata aacaaggacg aatcaatata cccagcacgt
    18601 taagaaatta tgcagctttg acaaaaggtt gcgtagtcat cggtgtatct aaccgaattg
    18661 aaatttggga tgagacacga tggcaagatt tttctgcagc agcagaagag aactttgacg
    18721 aaattgctga aagtatgatt gatttcggac tataagaata ggaagaggct gactaatgac
    18781 tgaaacattt caacactata cagtcatgtt gaaagaaacg gtagatggat tgaacatcaa
    18841 accggatggc gtttatgtag actgtacact cggcggtgcc ggacatagtg aatatttatt
    18901 aagccaacta agttctaaag ggcatctgta tgcgtttgac caagatcaaa aagcaatcga
    18961 tcacgccaag ctgcgtttag cttcttatgt cgaacaaggt atggtcacat ttatcaaagc
    19021 gaacttcaga gaattagaag aacgcttgag tgagcatgta gataaggtag acggcatttt
    19081 gtatgatcta ggggtttcct ctcctcagct agatgaagca gaacgtggat ttagttatca
    19141 tcaagatgca ccgttggata tgcgcatgga tcagtcagct cctttatccg cttatcacgt
    19201 aattaatgaa tattcctacc atgaattagt aaagattttc ttccgctatg gcgaggagaa
    19261 attttccaaa caaattgctc gtgaaatcga acgagtacga aaaacaaaac caatccaaac
    19321 aactggtgag cttgtcgaaa tcattaaaca agtcatccca gctcccgcaa gaagaaaagg
    19381 cgggcatcct gcaaaaagaa tttttcaagc tgtgcggatt gcagtaaatg acgaactcgg
    19441 tgccgaagag gcctctttag aacaggcaat ccggttattg aaagtcaatg gaagaatcag
    19501 cgtaatcaca ttccattcat tggaagacag aattgtcaaa agtatgttta aagaatatag
    19561 tacggtacaa gatctaccac cgggacttcc tgtcatacct gacgaattcc aaccagaact
    19621 gaaagtcatt actcgtaaac caatccttcc ttcagaggaa gagctaacag aaaacaatcg
    19681 atcacgcagt gcaaagttac gtattgcaga aaaaataaga atgaaagagg agtagaatga
    19741 tggcagaatt aaagaaaatg caagattacg aatatgattt acctgaattg gtggatcagc
    19801 cggaacaaca aatgcctgat tcttcttcga atcaagaaat cattcttcca caatcaccgg
    19861 caaaacgatt aaagcagatt tctgctttgg aaaaaattgc tgtggcaagc gtggcgattg
    19921 ctattgttgc tttatgtgtt ttaacagtta tgctgcgcac aaatatcagc ggagctgaaa
    19981 aagaaatcac gtcaatacaa acagaaatca atgataaaaa gcaagaaaaa acgagtttag
    20041 aacaagaaaa aaacgaactt tctcgtactg aacggattaa acaaatcgca gaagaaaaag
    20101 gattgtctat taatgacgac aatttaagga aagtgaagta aatgagtctt aaaaataaaa
    20161 ttcggcggtt tatggaaaag aaaaatctaa atccgatgaa caatcgcaaa aaagtaggta
    20221 tcattttatt tgctacgagt attggattgt tctttttatt tgccgtccgt ttctcgtata
    20281 tcgttattgg aggtcatgtt gctggtacct cattagctga aaaaacaaaa cagttgtacc
    20341 aaggaagtga agtagtaaaa gcaaaaagag gaacgattta tgatcgtaac ggtgtggcgc
    20401 tcgcagaaga tgcctcctct tattcaatta aagcgatact ctcaaaaaca tatacctctg
    20461 gggataaaaa actgtatgtt gaagaaaaga attttgataa aatagcagaa atcctgcata
    20521 agaatctttc tatagacaaa aaagatgcac tgaatatttt agaggacggc gcaaaaaaag
    20581 agctgtatca agttgaattt ggtagctatg ggaaaaatat ctcccaagaa accaagcaaa
    20641 acatcgaagc ggacatgaaa aaagaaggtg tcgctggtct ttattttgtc gaccatcagg
    20701 ctcggatgta tccaaatggc gtcttttctt ctcattttat tggatacgca gttccagaca
    20761 aagatgagaa tggcttagtt ggtaaactag gtttggagtc tgcttacaat gatatcttga
    20821 gcggtaaaga tggtaagatt atttatcaaa aagataattt tcaaaatcct ctgccaggta
    20881 cagtggcaga agaagaaaaa gctgtcgacg gacaagatat ctacacgact ttagacagca
    20941 gactacaaag ttatttagaa acactgatgg atcaagtaaa tgaagaatat cagccagaag
    21001 aattgacagc agtcctgatg aaagcaaaaa ccggagaaat cttggcaatg ggacaacgac
    21061 ctactttcaa tcctgaaaca atggaaggat tgactggaaa agatgctatc tggcgtaatt
    21121 tcttggtaca agatagttat gaaccaggat caaccatgaa agttttcact actgcagctg
    21181 ctatcgaaga aggagaattc aacgagaatg aaaccttcca atctggaaaa atccaagtag
    21241 aagatgctac gatcaatgac catgactttg gtgaaaaagg tgtgctgacc atgcgtcaag
    21301 ctctttcatg gtcaagtaac gtcgggatgg tcatactgga acagcgatta ggcggacgat
    21361 ggtataacta tttacaaaaa ctgggatttg gacaaagtac tcattctgga ttagatgatg
    21421 aagtaaacgg tgctttacct acattaaata ttgtcgaccg agcaatgagt gcttatggac
    21481 aagcggtagg tgtgacgaat ttccaaatga tgaaagcttt cacttctatt gcgaataacg
    21541 gtacaatgat tcaacctcga tatatcagca aagtggtgga tccccaaact ggagaagagc
    21601 gaacaactca aacagaagtt ctagggcaac ctttttcaaa agaaacaaca gaaaaagtcc
    21661 gtgaatatat gagagatgtt gtcgaaagcg aaaactacgg tagtgtttat ggtgtatata
    21721 gtgtacctgg atacaatgta tcggcaaaaa ccggaacagc ccaaatcgct tctgatacag
    21781 ggggatatca aacaggagat acagcctacc tgtattcgat tgtggagatg gttccttctg
    21841 aagatccaga ctatgtcttg tatctaacaa tgaaacaccc taagacatat gatcgaatgg
    21901 cattggctaa aatcgcaaat ccattgatga aacgggcaat ggattttaaa gaaactgaag
    21961 aagattcaga tacagaaaca aaaacagaaa aagtatccgt agccgattat cgtaatcttg
    22021 aagcggacgt tgcagcagct gatgctcaaa aaagtggact gcaacctgta gtgatcggta
    22081 atggtaaaaa agtacaaaaa caatctactg ccaacggtga tcagttgatc tctggagaaa
    22141 aactgatcct atatactggt ggtgataagc tgatgcctga cgtaacagga tggtcaaaag
    22201 cagatatcat gaagctgggg aaaatcctcg gtattgaagt tagttttgat ggagatggtt
    22261 attgtgtcaa acaagaactt gctccatatg aaaaaatcac tgaagacaaa cttagtttta
    22321 ctttagaaga ataagaagag aaataggaga gaaaagagca tggaatggac acaagcattg
    22381 attcccattg tcagcagttg tgcaatgaca attgccgcaa tgccgctatt tattggttat
    22441 tttcaaatga aaaagcaagg tcaggcgatt cgtgaggagg gaccaaagtg gcacaatagc
    22501 aaagccggaa ctcctacaat gggcggctta gtgtttctga tcggctctat tttgacagga
    22561 atttgggttg gagcttggca aaaacagcta actcctactc ttttcatctt gctttttgta
    22621 ttagcgttat acggagtaat cggctttctt gatgatttta taaaaatatt caagaaaaga
    22681 aacatgggac tgaactcgaa gcagaaattg attggacaga ttctaggggg aatcatcttt
    22741 tatcttgttt accgttctga aggttatcca ggtgtattga atttcttcgg actagatcta
    22801 cctttaggaa tcatttatgg tattttcgct ctcttctggc ttgttggatt ttcaaatgca
    22861 gtaaatctga cagatggcat cgatggatta gttgctggct taggaagtat ctcttttgca
    22921 gcttacggtc taattgcttg gcatcagcat cagtatgatg tattaatcat ttgcttaagt
    22981 gttttaggag gtttactggg tttcttcgtc tacaacagaa aacctgccaa gatttttatg
    23041 ggagatgtcg gttcattagc gttgggcgga cttttagcgg caatttctat aatgctaaac
    23101 caagaatgga cattgctttt gattggtttg atctatgtta tggaaacagc aagtgtgatg
    23161 cttcaagtta cttcctttaa gcttacagga aaacgaattt ttaaaatgtc tccaattcat
    23221 catcactttg aaatgtgcgg atggtcggag tggaagattg atacagtttt ttggttgatc
    23281 agcattgtga cttcgttgat cacattatgg atcgtttggt aggagatgac gggaaatgaa
    23341 aaaaatatca acatatgaaa ataagaaagt gcttgtctta ggactcgcaa aaagcggagt
    23401 aagtgcggcc aaattattac atgaattggg cgcacttgtc accgttaatg atggaaaacc
    23461 ttttgacgaa aatccggaag cacaagagct gctttcttta gggataaaag taataacagg
    23521 tagtcatcca atcgaattgt tggatgaaga attttcattg atggtcaaaa atccagggat
    23581 tccctacagt catcctttag tagcaaaagc ccaagaaatg ggtattccgg taattacgga
    23641 agttgagcta gcttacgaag tagcggaatg cccaattatt gggattacag gaacgaacgg
    23701 aaaaacaacg acaacaacga tgacaggact actactgaat gcaggagcag atcaaggaat
    23761 tgcacgttta gcgggtaata ttgggtatcc agcaagtggt gtagcgcaag aagcaaaatc
    23821 agaagataaa attgtgatgg aattgtctag cttccaactc atgggaatca cagatttccg
    23881 ccctcatata gcggtgatta ccaatatcta tgaagcacat attgattatc atggtacaag
    23941 aaaagaatat gtcaaagcta aatggaacct tcaaaaaaac atgacagaaa aagattatct
    24001 gatccttaac tggaatcagt cagaactaca agaattagcg caaagaacaa aagcacgcgt
    24061 actgcctttc tcgacaaaag aagtgttgga agacggtgtg tatgctgacg attactcaat
    24121 atactataaa aaagaaaaaa taatggaaat atctgaactt ggcgtaccag gtaagcataa
    24181 tgtagaaaat gcactagctg ctatttctgt agcaaaattg tatggtatat caaatgaagc
    24241 tatacgagaa acgttgcatt ttttccatgg cgtaccacat cgtacgcaat atgtaggaga
    24301 aatccaaggc agaaaatttt ataatgattc aaaagcaacc aatattttag cgactaaaat
    24361 ggctctaagt ggatttgaaa cgtctaaggt cgtgttattg gctggcggat tagacagagg
    24421 aaatacattt gatgaattaa ttccttcatt aaaaggaatc aaagcaatgg tcgtatttgg
    24481 ccaaacaaaa gaaaagttga tggatgctgg aaaaaaagca ggcatcgaga caatagtaac
    24541 agccgattct gtagaacaag cagttccttt agcattagaa aacagtacag atggtgatgt
    24601 agttttatta tcaccagcga atgccagctg ggatcaatac ccaaattttg aaactagagg
    24661 aaacagattc atggaagctg tgaaccgatt aaaatagaaa aagtagaagc gagcgataaa
    24721 aaatgaaaat tttggttaca ggcggaggaa cagggggaca tatttatcca gctcttgcct
    24781 ttgtcaatta tgtaaagact caagaaccga atgctgaatt catgtatgtg ggagcaaaac
    24841 gaggtctaga aaacaaaatc gtccctgata caggaatgcc tttccatacc ttggagattc
    24901 aaggatttaa acgaaaaatt tccatgcata acatcaagac ggtccgattg tttcttaaga
    24961 gtatccgtca agcaaaaaaa atcctcagtg attttcaacc agatatcgtt atcggtactg
    25021 gaggatatgt ttccggagcg gtagtgtacg ctgcagccaa aatgggtatt ccaacagtta
    25081 tccatgaaca aaacagtgta ccaggtgtta ccaataaatt tttaagccga tatgtggatc
    25141 ggatcgctct ttcatttaaa gatgcggctt ccttttttcc tgaaaacaaa gcagttcttg
    25201 taggtaatcc tcgagcacaa gaagtagcag atactaaaaa atcagatatt ttgaaaacat
    25261 ttgatttgga tccagaaaag aaaacagtct tgatttttgg cggtagtcaa ggagcactta
    25321 aaatcaatca agcagtatca gtttttttaa gtgaatatat tccttcttct taccaagttt
    25381 tgtatgcttc aggagataga tattatgaag agatcctaaa taaaataaat cctgaaatac
    25441 aaaatattag tgtccagcct tatatcaaaa atatggcaga ggtcatggct tccagtgatc
    25501 tgctggtggg gcgtgctggt gcaacttcga tcgcagaatt cacagctctg gggttaccgg
    25561 cagtgttggt tcccagccca tatgttacga atgatcatca gactaaaaat gcaatgagtc
    25621 ttgttcacgc aggagcagca aaaatgattg cagataatga actaacaggt gaatcactaa
    25681 gtcagacagt caacgaaatc atgggtgatg aagaattgca aaagcaaatg tgccgagctt
    25741 ctaaagaaca aggaatccct gatgcttcaa aacgtcttta tgacttagta aaacaaataa
    25801 tcaaaaaata aaggcggtgg tcttagtgag taagaaaaaa gaaccaaaaa aattgtctca
    25861 tccgtcttct gatgaaaaca atttgactcc ttggcaaaag gctaaccgaa aatatctggc
    25921 agaacaagag atgaaaaacc aagagccaaa aaaagaagac ataacattag atacacccct
    25981 ttcagattct gaagaagaaa aaacggttca agaggaacag caagaagaaa gccagtccga
    26041 gaaaaaaatc gaattttttg aagagatcaa gcaaaagaaa aacggtggac catataacgg
    26101 ttcttttttg aaccggctgc ccaatttaaa aagtcaacgg cacaaagtac tatttcgtcg
    26161 gttagctttg atcatcactg tattgggtat accgctgatt tttttgatct attatgtttc
    26221 tccttatagc aaattacaag cagttgcagt atcaggcaat aagacagtca acagccaaga
    26281 aatcatctct gatacaaaat tgtcattagg agaaaatgtt tggggacagt attttcatcg
    26341 atctacttat atcgatcgcc ttaaaaaagc acagccaaga atcgaaacag caaatataca
    26401 tttcaaaggg atgaatgaat tcgatttgga tgtaacagaa tataaagaga ttgctttgat
    26461 cgcaaaaaac aatcaatact acccagtgat tgaaaatgga acagtattag atgaaaaagt
    26521 agcaaatcct acaaaaaatc tccctatctt ggaagagttc aaagactctg caaaaatcaa
    26581 agaattaaca aagcaataca atcagttatc atcagaatta caaaaagcaa tttctgaaat
    26641 caagtacacg ccaagagcaa gcaataaaaa tctgatccaa ttgaatatga atgacggcaa
    26701 tcaagttatt gtaaatatca ataatcttgc gaaccaaatg aaatattatt cgcaagtagc
    26761 caaagatatg gatgaaaaag gtgtgatcga catggaagtt ggtatcttct cgcatcctta
    26821 cggtagcact caagaaacgg aagaatcggg ccaatcggaa gaaacaactg aaagtgaaga
    26881 aaatgcggat caaacaaacg aatcaagtga agaggcagaa acgcaaaaag cacaaacacc
    26941 tggatcgtct agcacaaacg gatcatctga ttcaaatgat tcaagtgaaa caagtcaaat
    27001 agaagataat ccaagtacaa ctccgtcaag tttaaatgaa aattgataaa acaactttaa
    27061 aaagtaagaa tgtactttct aaaaaccagt aatttatggt agaattggaa gcagtgaata
    27121 tatctattaa taagtatatt ttaaaacgga cgctagttgt tcgcttgtat atggaatagt
    27181 aagtaggagg gaatcccatt catggcaaaa acaggaatgt atgtaggcct tgatattgga
    27241 acgacatctg ttaaagttgt cgtggctgaa tatatcgaca gccaaatgaa tattattgga
    27301 gtaggaaacg caaaatcaga agggattaac cgaggcatta tcgttgatat cgataaaacg
    27361 gtccaagcga tacaacgagc agtacgacaa gcagaagaaa aagcaggtat ccagatcaaa
    27421 ggcgtaagtg tcggtttgcc agcaaacatg cttgaagtag aaaattgcca gggaatgatt
    27481 gcagttaacg gagattcaaa ggaaatcacc gatgaagatg tcagaaatgt ggcttcagct
    27541 gcccttgttc gttcaatacc tcctgaacgt caaatcgtgt caatattgcc acaagatttt
    27601 actgtcgatg ggttcgaggg aatcaaagat cctcgtggaa tgatcggcgt aagattagaa
    27661 atgtacggtc tgttgtttac aggacctaaa acgatcatcc ataacatacg taaatgcgtg
    27721 gaaaatgccg gattaatcgt caacgaaatg gtgattactc ctttagcgct gactgaatca
    27781 attctttctg acggagaaaa agattttggt acgatcgtca ttgatatggg tggcggccaa
    27841 acaacaacgg ctgttatgca tgataagcaa ttgaagttta ccaatcttga ccaagaaggt
    27901 ggcgaatttg tcactaaaga tatctctatt gtattaaata cgtcatttaa caatgcagaa
    27961 gcgttgaaaa taaactacgg ggatgcatac ccagaacgga catcaccaga tgaagaattt
    28021 ccagtagatg tgattggtca gtcagaacca gtgaaagtcg atgaacgcta cttgtcagaa
    28081 attatttcag ctcgaatgga acagattttc aacaaagcaa aagatgcatt ggaccaaatc
    28141 gaagcattag agttgccagg tggcgtcgta ttgacaggcg gagctgctag tcttcctggt
    28201 gttgtggact tggcacaaga aatcttcggc gtaaatataa aattgtatgt tccaaatcac
    28261 atggggctga gaaacccggt atttacaaat gtaataagta tcgtggatta ttcagcaaac
    28321 ttgagtgaag tgtatcaatt ggcaaaaatt gctgttacgg gtgaaacctc agcagctcgt
    28381 caaatggtag ttgaacaaga aacaacaaac acatatgaga gctatgaagc acctgaagaa
    28441 acaatctacg atgagccgga accaaaagag tccggagaaa atgtaaaaaa taaaatcaag
    28501 ggtttcttta caaatatttt tgattaattc atcctgggag gaataagata tggaattctc
    28561 aattgataat aatatcaatg acggcgcagt aatcaaagtc atcggagtcg gtggtggcgg
    28621 tggaaatgct gtaaaccgaa tgattgaaga aaacgttaaa ggtgttgaat tcattacagc
    28681 caacacagac gtgcaagcat taaaaaattc aaaagctgaa acagttatcc aattaggccc
    28741 caaatatact cgtggtttag gtgctggttc tcagccagaa gttggacaaa aagcggcaga
    28801 agaaagtgaa caatccttac gcgaagcttt agacggtgca gatatgattt tcatcactgc
    28861 aggaatgggt ggaggaaccg gtacaggtgc tgcaccaatc gttgcaggta tcgcgaaaga
    28921 attgggcgca ttgactgttg gtgtcgtgac acgtccattc acttttgaag gaccgaaacg
    28981 tggccgtttt gctgcagaag gtatcgctcg tttgaaagaa aatgtggata cattattaat
    29041 tatctcaaat aaccgtttat tagaagttgt agataaaaag acaccgatgc ttgaagcttt
    29101 ccgtgaagca gataatgttt tacgacaagg tgtacaaggt atctctgatt tgatcacagc
    29161 gccaggttac gttaaccttg actttgctga cgtgaaaaca gtgatggaaa accaaggtac
    29221 agcattgatg gggatcggtg tggctagtgg agaagatcgc gtagtagaag caacgaaaaa
    29281 agcaatctcc tctccattgc ttgaaacatc tattgatgga gctgaacaag tacttcttaa
    29341 catcacaggc ggtttggata tgacattgtt cgaagcacaa gatgcttcag atatcgtagc
    29401 aaatgcagca actggcgatg taaatatcat tctaggtaca tctatcaatg aagaaatggg
    29461 cgatgaaatc cgtgtgacgg tcatcgcaac aggtatcgat gaatcaaaaa aggaacgcaa
    29521 gtctagccga ccagctagac aagcacaaat gcaatcacct gctcaaaaga ctgtattaga
    29581 tatggatcaa gctaaaccaa cttcttcaga agaagaaaac agttttggcg attgggatat
    29641 cagacgtgaa caaaatgttc gtcctagagt tgatgattcc aattttgaca atatcgaaaa
    29701 aaaagaattt gatacattca accgcgaaga aacaaaatct catggcgatg atgaattaaa
    29761 tacgccaccg tttttccgtc gtaaaaaata aaggagagga agagcacatg attgctgaca
    29821 acttgcagaa aatcaagcaa gaaattcagg attcgtgtgc tcttgttcat cgtgatccga
    29881 aagaagttac attagtagct gtaacaaaat ctgttgaatc cgctcaagct gaagaattgg
    29941 ttagagctgg cgttatgaat tgtgcagaaa accgagtaga taaattatta gaaaagaaac
    30001 aagatttatt tgattttcct gaaataaagt ggcatttaat tggtaattta cagcgcagaa
    30061 aggtaaaatt gattgtaaat gaaattgatt actttcatgc gttggacagt ttaagattag
    30121 cagaagaaat ccagaagcgg ttagagaaag aattatcctg ttttattgaa gtaaatgttt
    30181 ctggtgagga atcaaaacat ggaatttcac cagatgagct tttaccgttt gtggaatctt
    30241 tagctgcctg cacaaaaatc aaggttgttg ggttgatgac tatggcgcct aaagaagctt
    30301 ctgatgagca aatccataaa gtgtttggta cgctgaaaga attgcgtgat cttgttcaag
    30361 caaaaggtta tgcccatgca ccatgtagtg aattaagtat ggggatgagt caagactttc
    30421 aaattgcgat tgaagaaggt gcaacattta tccgtgtagg aacagcgcta ttcaaagacg
    30481 aataaaggag gaacaaaaat gccgctttta aacagaggag caattgctaa ttttttcgga
    30541 ttagctgatg aggaagagta cgaataccaa gattatcctg aaacaacaaa aaaggctgta
    30601 cagccaacta aaaaaaatac aacacagaat caatcaactc attctgtatc tgctgcgaat
    30661 actcatgaaa aacaaaaaac ggcgacttca cgtcctgtaa cgcatgaaag tattcagccg
    30721 gctgaaaaga aaaaagtaat tgaactacat caatcaccta caaaaactgt agcgaaagaa
    30781 agaacagctt caagaacctc tacacaacct aaagcaaatc ttgctggaaa aatcactgta
    30841 atggaaccaa gagcttattc tgaagctatg gcgattgcta aacgaatcat tgctggagaa
    30901 gcaaccttag tgaattttca tttagtagaa gaaaaacaag cgagaagaat cgttgatttt
    30961 ctaacaggaa cagtttatgc actagatgga gatatcaaac gtgttggaga tgagattttt
    31021 ctttgtacac cgactgggat ggagattgac agttcaaccg ctcaatcttt tgcagatgcg
    31081 aatttgtttg atctgtaaga ggaggaacta cgatttatac tattgcacta ttacttcatt
    31141 tacttcaacg ggcagcctat ttctatagca ttatcttgat ggtatatgca ttgctctctt
    31201 ggtttccagg cgggtatcaa tcagggctag gacgattatt agctaagatc tgcgaaccgt
    31261 atatcagttt gttcgatcgt ctgcctttga ggattggacc cttggatttc acaattttag
    31321 gggcaatcct gatcttgaac ttagccgtac aaggtttagc acagatcgtt atatggataa
    31381 ctgtccattt agtttattga ttgaagcaac aaaatcttta ttctcagaat agataggagg
    31441 ggaaaatttt ggatgcaaat gtataccagc actttcgggc agatgaacgt acatttatcg
    31501 attcggtagg cgattggatt gaacaggttc aaggacaata tgcaccctat ctgaccgaat
    31561 ttcttgaccc aagacaatcc tatattttag aaacactgat tcgacaaagc agtgatttgc
    31621 gtttcatgtt ttatggcgga tatgaacagg cagaaagaaa aagatgtttg attttccccg
    31681 attattacga acctgtagag gaagattttg aaacagcatt gtatgaaatc cattatccta
    31741 gcaaatttgc cagcctaagt catgggaaaa tccttggaac tttagtggga acggggatca
    31801 aacgctctta ctttggcgat atcatctcgg acggtgatcg ctggcaagta tttattgcaa
    31861 atgaggtgga tcattttgtt gctgcacaag taacaaagat tggaaaggtt gctgtacgct
    31921 tggaaccaat caaatacaca gaaatgatta tgccgaaaga tagctggaca caagaaagag
    31981 gaacagttag ttccatgcga ctagacagtg tgatctctga gatttataat atttccagac
    32041 agcggtccaa gcagctgatc gaagctggta aagtaaaagt gaactggaca gaaaatacaa
    32101 gacctgattt tgtacttgaa ctattagata ttatttcagt cagaggttat ggcagagtcc
    32161 agatccaaga acttgagggg aagacgaaaa aagaaaagta cagggtactg ttcggtgtat
    32221 tacgtaaata aaataaaaag gtggtttact catggcttta actccattag atatccaaaa
    32281 taagacattc ccgacaaaaa tgcggggata taatcaagac gaagtagatg atttcttaga
    32341 tttagttgtt cgtgactatg aggaattgac tcaaagaaat cgagaattag aaaaagcagt
    32401 caaacattct gaagaaaaac ttgagtactt caatgaatta aaagatgctt tgaaccaatc
    32461 aatcatcgta gctcaagata cggctgataa agtaaaaaca agtgcaagca aggaatccga
    32521 agtgatcgtt acttctgcac aaaacaaagc agatgagtta gttgcgaacg ctgaaaaacg
    32581 tgcacatcaa ttaacaactg atgcagaaga aaaagcaaga aaaatcttga cagatgcaac
    32641 agaaaaagca agacagcttg cgacagaaac tgaagatctt aagaaaaaaa cacgagtatt
    32701 ccatcaacgt atcagcttga tgcttgagtc tcaattagaa caagtgaaaa gtccggaatg
    32761 ggatgaaatt ttacaaccat tctccagcta cgtgactgac agccatgaag tgatcaaaga
    32821 agttttagca aaacagcttg acaatgaaaa tgatactgat gtaaactcag acacaggagt
    32881 catagaagca cctatgacgg catttgatac acaggctatt gatatctcga tcgtgcctgg
    32941 tgaaaatgaa aacgagtaga acagaaaagc actttgttat tcttaaagcg agccgatgag
    33001 agtggaagtt cggtaagaca ctgcatggtg aaagatcctc tacttgagac ctgcttttcc
    33061 gaaattagag taagaagcag cggctgacct cgttattggt cacagagagt ttgcactaga
    33121 tagatgcaac taaatttggg tggtaccacg gcatgttcgt cccttgcggc tgaacatgct
    33181 tttttgtgtc cggaaaacaa ataaaggagt gtatggttga atgaaaatga aagaaacctt
    33241 gcaattagga aaaacaaaat tccctatgcg tggtaatttg ccaaaccgag aaggcgagtg
    33301 gcaaaaagaa tgggaagaaa atcgaatcta ccaaaaaaga caagagttga acgaaggaaa
    33361 acctagcttt gttcttcatg atggacctcc atatgccaat ggtaatatcc atttaggaca
    33421 ttcattgaat aaaatcagta aagacattat cattcgttca aaatcaatgt ctggctatcg
    33481 tgcaccatat gttccaggat gggatacaca tggattgccg attgaacaag tattggctaa
    33541 taaaggcgtg aaacgtaaag aaatgtccat ggcagaatac ttggaaaaat gtcgtgaata
    33601 tgcactttcc caagtagata agcaacgagc agatttcaaa cgcctaggag ttgcaggaga
    33661 ttgggaacat ccttatgtta cattagatcc ttcttatgaa gctgcacaag tacgcgtatt
    33721 tggtaaaatg gctgaaaaaa gctatattta caaaggattg aaaccaattt actggtctcc
    33781 gtcaagtgag tcttctttag cggaagctga aattgaatat aaagatgtaa aatctccatc
    33841 tatttttgta gctttcaatg tcaaagacgg caaagatatt cttgatgaag atacagcttt
    33901 tgtcatttgg acgacaacac catggacatt gccagcaaac caaggtattg ctgtaaatcc
    33961 aaaatttacg tatgtattgg tggaagccga tggccgtaag tttgtcgtag cgaaagattt
    34021 gctagaaaca gtccaatcag aaatcggttg ggaaaatgta acagttctaa aagaatttgc
    34081 tggacaagaa atggaatata tgactgcaag tcatccattc tatgaacgtg aatcacttgt
    34141 gattttaggc gatcatgtta ctttagacgc tggtactgga ttagtccata ctgctccagg
    34201 acatggggaa gatgactata tcgctggtag caaatataaa ctatctgtag tgtcacctgt
    34261 agactcaaaa ggattgttta cagaagaagc acctggattt gaaggtatct tttatgacaa
    34321 agcaaatcct atgatcactg atctattaaa agaaaaagga gctttgctga agctagattt
    34381 ctttactcat agttatcctc acgattggcg gacgaaaaag cctgtgatct atcgggcaac
    34441 tccacaatgg tttgcatcta tcgataaatt ccgtcagaat attttggatg aagtagaaaa
    34501 agtagagtgg gttatcccat ggggtaaaac acgtttgtat aatatgatcc gtgaccgcgg
    34561 cgattgggta atttcccgtc agcgtgcatg gggagtacca cttccgattt tctatgctga
    34621 aaatggagaa gcaatcatca caccagaaac aatcgaacat gtggcaaaat tatttgctga
    34681 acatggatca attatctggt ttgaaaaaga agcgaaagaa cttcttcctg aaggatttac
    34741 ccacccaggt tctcctaatg gcgaatttac aaaagaaaaa gatatcatgg atgtctggtt
    34801 tgattctggt tcttctcatg aagctgtttt acgtcagcga ccagaattat cattcccagc
    34861 agatatgtat ttagaaggat cagaccaata tcgtggctgg ttcaactcaa gtatcacgac
    34921 tagtgtggct atcaatggtg tagcaccata caaatcagtt atttctcaag gatttgcttt
    34981 agatggtgaa ggccgtaaga tgagtaaatc tttaggaaac atcattgcac cagaaaaagt
    35041 gatcaaacaa tttggtgcag atatccttcg cttatgggta tctagtgtag attatgaagc
    35101 agatgttcgt gtttctatgg atatcttaag tcaagtggca gaagtatatc gtaaaatcag
    35161 aaatacgatg cgtttcttat tagcgaatac agaagatttc gatcctaaaa aagatactgt
    35221 ttcgtacaat gatttacgtt ctgtagacaa atatatgacc gttcgattga accaagtaat
    35281 caaagaaatc cgagaagaag ggtacgacaa atataacttc atgcatattt accgtacagt
    35341 tatgaacttc ttgacggttg atctatcgtc attctacctg gattttgcta aagatgtagt
    35401 ttatattgaa gcagaagatg attatcaacg tcgttgcatg caaactgttt tctatcaaac
    35461 agctgtagct ttgacaaaat tattgactcc tatcattccg catacagcag aagaaatctg
    35521 gtcattcctg aaagaagaag aggagtacgt tcagttaagc gagtttcctg gttatgaaga
    35581 gtttgcaaac caagaagaat tgatggatac ctggactgct ttcatggact tccgtgataa
    35641 tgtcttaaaa gcattggaag aagcaagaaa cagcaaattg attggtaaat ctttggaagc
    35701 aaaactaact gtttatccaa aacaacaagt tcgtgaaatg ttaaaagctt tggatgcaga
    35761 tattgcacaa ttattgatcg tttcaccaga ctactttgaa gttatggcag cagatgaaca
    35821 agtgccagat aacgctatgg tatttgatga tgttgctatt acagtggaaa aagcagacgg
    35881 ggaaacttgc gatcgctgtc gccaagttcg taaagatgta ggagtagatg aaaaacttcc
    35941 tcatctatgc ggtcgttgtg caaaaatcgt tgaagacttc tatcctgaag ctgtagctga
    36001 aggattcgaa gaaaagtaaa agggaaaagg gggtgtgaca tgttctttgt cacaccccct
    36061 tttgttatca atcgtttaat tttccacgtt cacgatacca gttatctggt tgccagatcc
    36121 attcgaatcc gtctttttca agtagttcga aagctgcttt aggtcccatt gatccagctt
    36181 tgtagttggg aaaatccggt tgtgtttggt cccaagcttt tcgaatgaca tccacgatat
    36241 gccaagattg agcgacttct tcccaatgag agaagttcgt tccatcacca ttcaacgcat
    36301 ctaatagtaa tttttcgtaa gcttctgggc tattttcaac catttctgca ctatttctaa
    36361 attccaattt gattggttcc gtttcaaatc cttgccctac ttctttccca ttcaaggata
    36421 aagaaaatcc ttcagttggc tgaatataga tcgttagaac attaggtgga agtgtcgtat
    36481 cgtcacatgg ttcatcgaca gatgttttga atacattaac aggaacttgt ttgaatacga
    36541 tgttgatccg agtccctttt tcagtcaaac gtttgcctgt acgtacatag aaaggaacac
    36601 ctgaccaacg gaagttatcg atagtgaatt tgcctgcgac gaatgtttca gtctctgatt
    36661 gagcatccac tttgtcttct tcgcgatagc ccttgaattg tacaccatcc aattcacctt
    36721 gagcatattg cccgcgaacg aagttttcta acacttcttc ttcgttataa atgcggatag
    36781 ctttcaatgc tttgatcttt tctgtacgga tttctttttc ggaaaatgct actggcggtt
    36841 ccattgcaag taatgctaca acctgtaaaa tatgattttg caccatgtct ttaagtgcgc
    36901 cactatgatc gtagtagccc ccgcgatctt ctacaccgag gttttcgcca aaagtaattt
    36961 ggatattgtc gatatagcga ttgttccatt gagcctcaaa aatattattg gcaaaacgga
    37021 tagctgagat gttttggatc atttcttttc ctaaataatg atcaatcctg aaaatatctt
    37081 gttctgggaa tacttctctg atttgctggt tcaattcaaa agcagactgg taatcagaac
    37141 cgaacggttt ttctatgatc aaacgattga agccattttt tgtcataata ttttgtgatt
    37201 tcaaatgaga aacgatcgtt ccaaaaaatt gaggtgccat agccaaataa tagacacggt
    37261 taccgtttaa ttgatagtgt ccatctaatc ggtcagacaa ttcttttaat gtctgataat
    37321 gcgttgaatc atttacatca tgggattgat agtaaaaatg gcttgcaaag gtagttgctt
    37381 cttcatctga aggattcaat gcacggattg tttctttgac aacttcacgg tagtgctcat
    37441 cgctccaggg acggcgagcg gttccgatta cagcaaaatg ctcgcctaaa tttccttttc
    37501 tgtaaaggcg gaacaaagac gggtacaatt tacgctgggc taggtcacct gtaccgccga
    37561 atatcgtaaa caatacattt ttttcattag acatgtggat acactccttt atattttatc
    37621 gacaaaaatc gtgctggccg ccttaaagct gacggggatt ttctttctat cattttggat
    37681 agtgatcggt ccttcataag ctgcgatgtc aacgatctca tattcttcgt tgatattcag
    37741 gtcaatagtg actaagtaat ccaacaattc tttttcatca agcactcgtg cgatacgcac
    37801 ttttgtaccg acaggatagg actccaatgt ttgtcggcgt tcttcatgga caacttcctc
    37861 ttttttagga atcgatcctc catgaggaca atgttcagga tgattcaaat agttttctaa
    37921 atgatctgca agatgttccg aagtcacatg ttccaatact tcagcatcat catggacttc
    37981 attccagcta tagtctaaat gttcaactaa aaaaacttcc cataagcgat gtttgcgaat
    38041 cagactgcta gctttttgca gtccgcttgc agtcaattgt acaccttgat aaggggaatg
    38101 ttctacaagc tcttctttca caagtttaga aatcatttca ctgacagatg cagctgagac
    38161 atctagacta gatacgattt gtttattgtt gactttcgtt gtatctccac ctagttctaa
    38221 aatgattttc aaataatctt ctcgatttgg tgtcatattc gatcatcctt tcatggtaaa
    38281 aaaccatcat tagtaagtgt aacaaaaaaa acgttaattg actatttttc taaataaaaa
    38341 acaaaggatt tttagacgtt tttacaacaa aaaacgaaag atgatagaga agactcattc
    38401 tttcgtttat aaaggatata tatatacatt gggagggatc tatttttcag ataacaactt
    38461 atatgaagtg tctgcagatt cgtcataaag agtttgttcg ggataagaaa agataagata
    38521 aaaaccatac tgatcacgta cgactaaacg atattcatct atttctacca cagatgtgcc
    38581 aagagactga ccgttgatca aaaacgtgta atcagatgta atctgtaatt gttgtttttg
    38641 ctggctatca ctaaagaacc atgtaccttg atactttgag agtccttctg acttttccgc
    38701 ttgttttttc tttttcaagt aaataaaact tgagagaacg gtaatgagtg aaccaagaaa
    38761 atagatcatt ttttttatca ccaaatcact cctttatgag aaaataatcg catagacata
    38821 ttctttcttc tttatttcat tgtaccgaat aaaagctaaa atttctctaa gactttcgac
    38881 tggttttttt actgtttttc tacaaattat gataggatac atagtaggaa gaaaggtgac
    38941 ataatttgaa gtatcagcaa gtggaaatag ctttttttat tgaccgcccg aatcggttta
    39001 tagcacattg tatgaaaaaa gacggagaaa taattattgc gcatgtcaaa aatacaggta
    39061 gaggaaaaga ggtcctgata ccaggcgctg aagtggctat tgtatttgct cctggaccta
    39121 aacggaaaac cgcctatgat ctgattgctg taaaaaagaa gggtgactgg tttaatatcg
    39181 atagtcaatt gcctaatcgg ctggcaattg atggtatttt agacggcacg atccttttac
    39241 caggattaac tggtccattt acggtataca agcgtgaagt aacttatctt cactccaaat
    39301 ttgatattta tttagagacg gtggtcggac aaaaagcatt tgttgaagtc aaaggtatga
    39361 cacttgaaaa taaagcgatt ggtgcttttc ctgatgcgcc cacactcaga ggattgaaac
    39421 atataggaga attaacgtat gccgcacaag atggttatgc cgcttatgtc ttgtttattg
    39481 ctcagttcga acatcttcat ctggcaacga tccatgaaga aatgcaacca gcactagctg
    39541 atatggttcg acatgcgcag caaagcggag ttcaaatcct cgcctataat tgtcaagtat
    39601 cggcagatga ggtaactgtc aagcaggcca ttccatttga tgtagatatc ccttttgaag
    39661 atcctataca atagaaagaa ggtaaaataa tgatcaactt aggtattatc ggaacaaatt
    39721 ggattactca tcaatttgtc caagcagctt taagcacaaa aaaatatgaa ttgacagcgg
    39781 tatattctag acatttggaa aaagcacagg aatttggttc tcattatgaa ggggatatcg
    39841 aattcgcaac agatttgaag acttttttca atattactca tatggacacc atttatattg
    39901 cttctccgaa tagtcttcac tttagtcaag ctaagcaagc aattttggca ggaaaaaatg
    39961 tgatagttga aaagccagct ttttcgacgc caaaagaaat ggatgaaatc atccatttgg
    40021 caaatgaaca caatgtgtat ttttttgaag cagcaagaaa tatccatgaa tcaggtttta
    40081 aaaagattgc cgattactta ccattaaaag acgagataat cggtgcaaat ttcagctata
    40141 tgaaatattc ttcgcgctat gaccaagtat tagatggaga agaaccgaat atcttctcga
    40201 ctcatttctc aggtggtgca ttgatggatt taggtgttta ccttgtatat gcagctgttg
    40261 cttggtttgg aatgccaaaa gaagtccatt atttcccaag aaagatttct actggtgtag
    40321 atggtcttgg atgggggatc ttacgttatg agaattttga tgtatcgatc cagccaggta
    40381 aaatcggtga ttcttattta ccgtcagaga tttattttga ctcaggaacg ctagtgatga
    40441 atggagtcaa tgcaattgaa caagcacaat ttcatgatcg cgcgcataaa gaaatcattg
    40501 atttggcggt aacagctgca gaaaatccaa tggcagatga agcagaggat tttgccaatg
    40561 tcatggctca tccgaaagat ccagcttggg gattgttgta tgaagagtgg atcgagctag
    40621 ctagaaatgt gaaccaagtg atttatgatt taagaaaaaa tggcggcatc aaattcgatg
    40681 cagataatga ggaagatttt taatgaacga atttgtacaa gtatttcccg aaaattggca
    40741 gaaaaaatat gaggataaag ggtttatctc accttctctt attcaacgag cagtttttca
    40801 gccactaagt aataaacaaa gtatagtagc ggtttctcct acaggttcag gtaaaacact
    40861 ggcttatctt tggcctctac tactaaacgt ggaaccaggt gaagcaagtg cgttggtcat
    40921 ttttgcttct tctcaagaac tagctattca agtagcagat gttgcacgtg aatggggaaa
    40981 agacaaagag ttgaaagtcc aatctttggt gggcggagcc aacgtcaaac gtcagattga
    41041 gggtttgaag gaaaaaccag aaatcttgat tggtacacca ggaagaatat tggaattgat
    41101 gaaagcaaaa aaaataaaag cacatcaagt gaaaacaatg gtatttgatg aagcagacca
    41161 gctatttgac gctgggaaca gccaaatcat tgatcaaatt cttcatcaag ctccaacaga
    41221 gtatcagcta gctttttttt cagcgacagc agatcgttcc cttgaaagca ttgaaaaaat
    41281 cactgggaaa acgtttgaga caattgacgt gacagcagag gacgattctc gaaaaggact
    41341 gagacattac tttttacgtg taccgatacg aaagaaagat gactacttga gacgtctcac
    41401 gcatatagaa gattttcatg gtctgatttt ctttaatcaa ctgactgaat taggcgtaat
    41461 ggaagaaaaa ttgctgtata gaggtgtacc ggtaggaagt ctggcctctg atcagaacaa
    41521 gctactccga aaagcagcgc tagaacaatt caaaaagaaa atggtcagag cacttttgac
    41581 cacagatgtg gcggctagag gtttagatat tacaggtctt ccttatgtag tgaatgcaga
    41641 agttccgtta agtgaagaag cttatttgca tcgttcggga agaactggtc gaatgggtaa
    41701 tgaaggaata gtaattacac tcgtacaaga taataatcta agagatttaa aacggctttt
    41761 acgtccatca aatataacac ttgaagagat ttttttatac ggaggtaagc tgcaaactga
    41821 gcagccaacc aaagaagatg cagctcctgc agtaaataaa aagtatgcga aaactttttc
    41881 tggaaaggag cagaacccag aatataacaa agaaaaaata agaaaaaaag ttaaaaataa
    41941 atcaaaaaaa gagagaaata aaggagcaag gcgcaaataa gcgccttttt atgctatgat
    42001 tatgaaaacg ggaacaaaat tggttgccag aggaggggtt atgtgaaaga acgtcaagaa
    42061 gagatcttgc agctattgac agaaaaccaa caaggattga cagcaagtga tgtagctgag
    42121 cgcttaacta tcgatcgaag caatgcaagc cgatatttaa gtgaactata caaggcccat
    42181 catattgtaa aaaccgctgg ccgaccagtc gtttactctt tgccaacgga aaagtcaaaa
    42241 tctgatgaag tgcatgtcga ctcttctacg caagtgactt ttgaaacact cgttggagaa
    42301 aatgattctt taaaagtcag catacagcag gcaaaagctg cgattcttta tccaccgcgg
    42361 gggttgcata cgattatttt tggagaaact ggtacaggga agtcgatgtt tgctgaatgt
    42421 atgtatcatt ttgcaatcga ttcagagatg ctttctgcag atgcgccatt tgtttctttc
    42481 aattgtgcgg attatgctca aaatccgcaa ctgctctttg gacacatctt tgggatcaaa
    42541 aaaggggctt acacaggagc agctcaagat agtcccggtc taatagccaa agcagacggc
    42601 ggtatattgt ttttagatga gatccaccgt ttaccgccgg aagggcagga aatgctgttt
    42661 actttcattg ataaaggtat ttaccgtccg cttggagaaa gtgcacaagt acatgaagca
    42721 tctgttcaga tcattggggc gacgactgaa tcttcagaaa gtttcttatc tacgttcaat
    42781 cgacggattc ctatggcaat caccttgccg aatcttgctt cacgttcact ggatgagcgt
    42841 tatgaaatca tctctctttt tatcaaacaa gaagcgaatc gtttgaatca acgtatcgat
    42901 atcgaaaaag aagcgattct tgccttcatg ctttatgatg cggaaggaaa tatcggtcaa
    42961 gtgaaacgag acttgaaact agtctgtgca aaatcttttt tacattaccg tactcatcat
    43021 gagaaaaagc taatcattcg aaaagaagaa ctttcccttc aagtacaaaa aggattactg
    43081 aaaatcaagg aaataccgga acgtctcgac cgattcatgg acagcaaaag tcagtatttg
    43141 acatttgaac caggatttgc tgatgttgtc tggtcacaag atccagaacg aaacatgcag
    43201 gtctataacg atattgagga aaaagtcact tctctttccg aaaccggtgt ggagaacatt
    43261 gatctagaga ccctcatttc aaaagatgtg gatgcttatt tccagacata tgtcaaagaa
    43321 ttgactaaaa gttcgattcc caaagatctt ttgccagatg aaatctggcg gttaaccaat
    43381 caattgtatg atgtggctga aaaacggtta gaccgtattt ataatgaaaa agctcgtttt
    43441 gcttttgctt tgcatctgca aagtacattg gatcgtgtga gagaaggtca tatgatcgtc
    43501 cacccagatt tgaataacgt acggaaaaat tttaagaggg aattccaggt agcaatcgat
    43561 ctttcaacga tcattgaaga agaagaacaa gttgagattc cttttgatga aatcggcttt
    43621 attagtatgt ttctttctat caatctagga gaaagtgagc ctgttaaaga aaacaaagta
    43681 gatgttctca tattgatgca cggcagacag actgcttcaa gcatgttgga gatggcacaa
    43741 gaactattag gaacaaaagt agggaaagct tttaatatgc cactggttat ggaagttcaa
    43801 acaatgtatg aagaagtgtt acaatatgtc aaaaactatc aagagcattt gacgaatggc
    43861 ctactcttgt taacagatat gggatcatta aacaccttca gtgatttgat ttatgaagag
    43921 actggcattc ggacgaaagc tatcacgatg acaagtacca tgattgtgat agaagcgata
    43981 cggatggcaa gtgttggaag aagcttagaa gatatttatc aaaatatcca gctttccttt
    44041 gaatcgatcg tacgtgatca gttcaaagcg gaaaagtctg aaactttaca gcgtaaaaaa
    44101 gccgtaatcg tgacatgctt tactggtgaa ggagtagctg ccaaattata tcagcgtatt
    44161 atgccagtga ttaatcaaaa taaggtagaa ctgatccaga tgcagttttt agaacgtgaa
    44221 tcattcaaaa aacacatcga tgccttattg gaagaatatg agatcaaagc aattgcggga
    44281 acagttgatg ttgattatca aaatatccca tttttttcag cctatgacgt ttttgatgat
    44341 gaaaaactaa atattttaaa gcgtatagct gatgatgaga tcccgacagc taaaattgtc
    44401 gattcacttg ctggatcatt aagcgatgtc ttttctattg atgaactgat ccgttcattg
    44461 caaaagacag ttcagcagat ccagaccgat ttgtcgatta tcgtggaacc tggagtagat
    44521 actggaatcg ttatccattt agccttcatg ttagacggat tgatcaaaca agaaagccat
    44581 cggcaatttg agaaactgtc tattttctca aaaatttatc gtttggaaat ggatatcgtt
    44641 cgggcaaact tgatggcact agaacgaaaa tatcaggtaa aaattccaga agatgatatc
    44701 gcatttctta cacaaatgtt tcttgaaaat aaaataaaaa aatgaacaca ctaatcatac
    44761 tgtttacaca ctaaacatct gtgtgcgcac tataaaaaag agctaaaaag catgaaaacg
    44821 ctatttcagc tctttttttt attggcatgc ttcttgcgtt atataaaagt gtaaaaaaat
    44881 aaaaggagtg ttaaaaatgg caaaaaaaac aatcatgtta gtttgttcag cagggatgag
    44941 tacgagttta ttggtcacaa aaatgcaaaa agcagcagaa gaaaaaggga tggaagccga
    45001 tatttttgcg gtctctgcct cagatgcaga taataattta gaatctaaga atgtcgatgt
    45061 attattatta ggtcctcaag tacgtttcat gaaagctcaa tttgaacaaa aacttgcgcc
    45121 taaaggtatt ccattagatg tcatcaatat gcaagactat ggcatgatga acggagaaaa
    45181 agttcttgca caagcagaaa atctaatgaa ataaatcaag tatgcagttg ggggtataac
    45241 aacgtggaag atcaacaaaa tctagaagcc atcatggggt taatcatgtt tggcggtaat
    45301 gcaaagagcg atgcaatgga agcgattgcg gctgctaaaa tcggtgattt tgagttagcg
    45361 gataggaaaa tcgctgatgc agaagaatca cttatacaag cgcatcatgc acaaacagac
    45421 atgttgacac aagaagcaca aggaaatcat atgcaagtga cattattgac tgttcacagt
    45481 caagatcact taatgacatc tattgcgttt actgatttag caaaagaaat catcgaactt
    45541 tatcgtcgcg tatacagcga ataaatacaa cttctttttt gaacggaaga agaaaaattt
    45601 ttgaacggat tttttatttt gttataagga gaactctctt tatataaaaa acttatagga
    45661 ggaagtaaaa aatgaacgga ctatcaagtt ggatggagaa atacatcctg ccggttgccg
    45721 caaaaatcgg agcgcaaaaa catttagttg ctttgcgtga tgcttttatc ggcatactgc
    45781 ccgcaacaat ggcgggatca gtcgctgtaa tgatcaatgc aattattcgt gatttaccgc
    45841 aacagtttaa cagtacctat gctgacagtt tagcagcaga caaaggaatc tttgccgtat
    45901 tgaatgtcat catcggaatc aatggttttg tctggaacgg tacactagca atcgccggat
    45961 tgatctttgc cttttcttgg gggtataatc ttgcccgagc ttatggagta aatgatctag
    46021 ctggggggat cgttggttta gctaccttga ttcaaggtat ttcctttggt ccagcattat
    46081 cagcagcatt agatgtgaat gttccttcaa atgtcgcaga tgcaatcaat agttctgaga
    46141 ttggtgcaac gattgcagat ggcacactgt cagttggatt atggggttgg ctaaaactag
    46201 atcatttgaa tggaaacgct tattttacag ttatgatcat gggagctatt tcagtcatta
    46261 ttttttgtaa attgatgctt gccaacatta cgatcaaaat gcctgattca gtaccaccag
    46321 cagtatctaa agcatttgca gccattttac cagcgacgat cgctttatac gtcattgcta
    46381 ttatcaatta tatcgtaggt cgtgtagctg atgggcaact gatcattgat ttggtgcaaa
    46441 aatatattgc agaaccattc ctaggattat ctcaagggtt gggagcagta ttgatcgtca
    46501 cagtatttgt tcaagtattc tggttctttg gtattcatgg atcaaatgta ttggcaccag
    46561 tgctagaggg aatctgggga caagcacaac taatcaatat tgatattttc caaaaaggtt
    46621 ataacggaaa aactggtaca ccagccgtgt tagatgcaat cgaagatgga aaagcttata
    46681 tgtgggtccg cggatcgttc gatgcttttg catggtttgg cggatcaggc ggaacgatcg
    46741 tcttactgat agctatcttg attttctcta aacgtgcaga ttatctaaca gtagctaaat
    46801 tatccattgg gcctggtatc ttcaatatca acgaaccagt gatgtttggt ctgccaatcg
    46861 tattgaatgc aatcatgttt atcccattct tgattgctcc agtagtagca acagcaattg
    46921 gatggacagc tacttatctt ggcctagtcg ctccggtatc gcagcaagtc acatgggtag
    46981 taccgccgtt cttattgtca ttcttagcaa caggagcgga ttggcgggca ccgatcgtaa
    47041 cattagtatg tatggtcgtg actttcttga tttgggcacc atttgtcatc tctgcaaaca
    47101 aaatggaccc tgccgcaggc gaacaacaat aagatgaacg tgaggagcgg gacgctttaa
    47161 gtttcgttcc tcataatgaa ttttcgagga ggaactgaaa tgattacaat tgccagtgca
    47221 atgcaacaag atgaaatcaa agaattgtta gaaggataca atgaagaagg aatgactttt
    47281 acatttaaag aaaaacaagg aatcaagctg ttctttgaaa caagtgcaga agatccggaa
    47341 gttgcggcta aaaaagcaaa ggaactaatc aaagcacagc cttggggaac agtcctttat
    47401 tttcaatcaa cagctgttta gaaaatggtt taaaaagata ggatggttga gatgataaaa
    47461 aacggtttat ttttatgtag tattggttct ttgatcgtgt tgtatagttt gaatccacat
    47521 tcgcaaaggt atgatttgta tagtatggtc acaggtcttt ttctaacagg attaggaatc
    47581 tatttcttca tgaaggggaa aaaaagagaa gaagcaaagg agaaaaataa ctaatggaaa
    47641 tcacgaaaaa attaaatatt ccagcatcgt ttttttacga taaagttatg gactctgtcc
    47701 ttttcgatgt acgtaaagcg accggcaaat cagtaactag aaaacagctg aaaaatttgg
    47761 agtacgtcaa acaattctcg caaaataacc gggctcgcat aaaaatcgaa gaagtcattg
    47821 aaaaccagtc ttataagttt cgtacatcga caacgaagaa tgaattcgtc gttcattatc
    47881 aaatcaaacc attggacgat tcgacctgtg aggttcatta cacagaaaaa atggagtctt
    47941 atggcatgct tcaaaagttg aatgatatgc ttttaggaac aatcttgatg tattttaaac
    48001 ggagacgttt caaaaaaatg ctagatatga tcgaagcaac gtattaaatc aatgaaacat
    48061 ggtactattt agttattgaa aaatgaagta agctagaagg aatttttcat aggaagatag
    48121 atctttcctg cgaatcctca ctagcttttt tgtaggaagg ggcagcaaaa tgacaaacaa
    48181 agtaagagag ctaggtgtat cttcgattga ggaaatgttt gatttagcca cttatgcatt
    48241 taatggggca gatacacctg aaaggcgaga acgttttcgt acacttgcgg agaattcttg
    48301 gaattacgga ttttttgatg aggaggatcg gctaacaagt caagtaatgg cgaccccttt
    48361 tccagtgaat ttttacggac aagagtacct aatggccggc attggctatg ttgcttctta
    48421 tccagaagca aggggacaag gcgggatcaa tcagatcatg gaaaagatcc ttgaagattg
    48481 ccgtgatcgt aaagtaagct tatcttatct ggcgccattc tcctatccct tctatcggcg
    48541 ctatggctat gaacaatcat ttgataaaat cagttatcaa ctaaacagtc gtgatgtgcc
    48601 gtttatcaaa aaaaaatctg gaaaaataaa gcgtatggat tttgaagatg caaaagctgc
    48661 aatcagaaga atttatgaac agatgccgga aaaccaacga gctggtctga agcgcgaaga
    48721 ctggtggtat acgtataaat tcaagcaaaa aggcaattac cagtttgctt tgcattttga
    48781 tgataatgag gaagcaacgg gatatatcgt ttatcagctt gcaacgtctt cctttattat
    48841 tgcggagtgg ggatttttgg atcatgatgc tttttgcagc cttgttcgct tcgtaagttc
    48901 tcacaatggt gcttttgaaa catttgaata ttcatgcggc tacggcggta atgatcaaaa
    48961 ttatctatta gaaaatccat ttgcttctgt aatgatcaca ccttatatga tggcgaggat
    49021 cgtagatatt tctttgtttt tggaaaatta tccatttaaa aagagacaag ctgcatttgc
    49081 cctacaaata gaagaagatc attatgcgaa atggaatgaa ggaatcgtgg aagtaacaat
    49141 cgaaaatgga aaaaatcatc tctcaaaagt agaacaaaca aaactcccaa tcgttcgagg
    49201 aagtatccaa catatcacgc agctattatt agggtatcgt aaagtggaag agttggtatt
    49261 ccaagaaaga atacaggtga caaaagaata tgaagaaacg ttaagctcaa tcttgccaca
    49321 gcaacagcca attcttaatg actatttttg ataaaaaacg ggtgatgaca atatttttgt
    49381 caccaccctt ttgtttttca tttggcattt gaaggaaaat gttaaagtaa atcctctttt
    49441 ttcgtaaatt tgaatttttt gttttctttt gttttagggt tttctttttt gtggtcttgg
    49501 attgcttctt tcgtaatctt ttcccgattt tttttagatg aatctaagcg ttctgcgtat
    49561 actttttctt ttggcttatc attcattgga aaggacctcc ctacattatt tcattctacc
    49621 tctagtttat catctgttaa ggactagtgg aaacgttttg cctaacttat aagctgattt
    49681 ttttagcaga taagcttgca agtaaaaaac aaacaagcta caattgattt attgaaattg
    49741 ttcctgtagc tcagtaggat agagcaatcg cctcctaagc gataggtcgc tggttcaatt
    49801 ccagtcagga acgtacaaat aacccctgta tcctttgcgg tacagggggt tattttgtat
    49861 aagtagacat tgtagtttct aaactgctat gtcctaaacg tttcgatacg ctaagtatat
    49921 ttactccttg ataaagtaaa atagatgcat gcgtatgtct tagtccatca ataaacagtc
    49981 gaagagaaaa tagggaaaaa ttgattacta aagaaaaact tactaggtcg acggtgtagt
    50041 tgattttcat acttcaatag attcgaatta aacgatttcg attggcttat accagtccta
    50101 tccaacgaaa gatatatcgt tcttaactct agcggtataa cttgaagctt tacgtaaagc
    50161 caatgggaat gaactggaga tgacttttta ttatttttag taatagctga tgggttaata
    50221 cttacaactt tccttttcaa agtaccatat aaaaaaacgg tggggttgtt tagcgaaata
    50281 aaggatctaa gccaatagct tagatccttt attctatgct ttatattatt ttttgcatgt
    50341 gtgcgaaagt atactcaagc ccaatcgcca tttcggaaaa tcggtactgt agagccatct
    50401 tcacggattc cgtcgatatc catcttgtca gatcctacca tgaaatctac gtgggtttga
    50461 cttctattca atccagcttc tgctaattct tcatcggaca tttctgtacc gcctttcaca
    50521 ctgaaggcat aagcagaacc tagtgctaag tgattcgatg cgttttcatc aaataatgta
    50581 ttgaaaaaga tgatgccaga ttgagaaata ggtgaagggt caggtacaag tgcgacttct
    50641 cctaaacgac gcgcaccttc atctgtatca agcagttttg ctaagacatc ttctccttgt
    50701 tcggcagaaa aatcaacaac ttttccatct ttaaaagtaa atttcatacc cgagatgatg
    50761 gtgccagcat aactcagtgg ctttgtactt gaaatgtaac catctactcg atgactgtca
    50821 ggtgctgtga acacttcttc cgtcggcata tttgccatga atttttctcc acgagcatta
    50881 tagcttccag cgccttccca aagatggttt ttaggcaatc cgataatgat atctgtaccg
    50941 ggagcagtat agtgaagggc agaaaattgt tctcgattca attcttctgc tttttttgct
    51001 aatttttcat catgcttctt ccatgctaag acagggtctt cttcatagac acgagtcgtt
    51061 ttgaaaatct gatcccataa tgcctcaact tgtttttctt ctggcagttc tgggaagact
    51121 tttgctgccc attgtttacc agccgcagcc acgacagtcc aactgacttt atttgcttga
    51181 gttgccttgc gtaaattcat tagtgctttg ccattcgctg attgataaga cgctactcga
    51241 tggctatcta caccagcaaa tgcatcggga tcggcagaaa caacgctgat cctgcttgct
    51301 cctttttcaa gccattcatc cgcttgatcg attttagatt gtggtacatt ctcaatacga
    51361 tccgttgcag catgtaaaag aaattctctt tggatctggt cgtcagtcca ttgaacgata
    51421 acctcagcgg ctcctagttt ataagcttct tgtgtgatca atcgagcaag gggtgcctgt
    51481 tccacgctga tctgtaaaac aactgtgtgt cctttttctg tggctacgcc agtttctgca
    51541 attaagcgtg catatttttt tagaagttca ttaaaatcag ataacataat aaaaattcct
    51601 cctcaccatt ttttctggta actattagca tgataccatt taattatgat tcaaacaatg
    51661 aggctttaaa taaaaaaagg aggttatttt tttaaggtta agtttcatga tatatgttac
    51721 tacttgctat ttcagcttgt gaagaaaatc aaaaactaat tttgcatatc aaaaaaaaca
    51781 tgttacaatg aaattaatca atggtggaag cgttataaaa aaattaagga gattaaaaaa
    51841 tatggcaaga aaaaagacga ttactagaga acagattttg gcagctgctt atgaagtagc
    51901 tgccaccgat ggatttacac gatttactgc gagaaacatc gcgaacaaaa tgaattgttc
    51961 cacgcaaccg atttatcttg agtttaaaaa tatggatgac ttgagacaag ctctttttga
    52021 gcagatctat gatcatttac aatatgaagt gttcactgtt gagcatacag ggaatacgat
    52081 tatcgatctt gcttttaatt atatccattt tgcaagaaga gagaagaagt tgtatcgttc
    52141 actgtactta gaagaatatg gtggaggaaa agagatgcag aatttctctt atacttactt
    52201 tgtgaataca gtgaaacgcg atccagctta tgtgaatctt tcagaagagc agatcgaatc
    52261 tttgtataat gggacatgga tcatagctac tgggatcgca gctttgatgt cttcaagcat
    52321 catccatcca actgatgaac agattgaaaa gatgatccaa gacagtatag atgctatctt
    52381 gaaattcaaa gaaccaatcg aaatcgattg aatatactca aaagttccac aaatcagtag
    52441 gtaacaagag atgtgtcaaa ataaggaaaa gttcgttttt cttacagcgt atgcattttt
    52501 aactcccgaa gaactcttcc atgaatgcaa tgaataaaag agccatacag attgaataaa
    52561 tctggatggc tcttttattg caagtatatt aaatttttgc gactagttct ttagcgaaag
    52621 cttctaaatt ttcgatatct tcttcttcag cattcagatc cactttaaca ttttcggctc
    52681 cttttgatgc gcctgttttt gcaaaagcag catcgaaatc atccaccgat ttgcagaatt
    52741 catcgtaaaa agtatcacca gatccgcaga caccgtaaat ttttcccaat agatccaatt
    52801 cttgcaagtc ttcataaaag tctacgatct catcaggcag atcgccatca tcgtatgtat
    52861 aagtagctac tacgcaaata tctgcctcct cgaattcatc tgcatctact tgggtacatt
    52921 cgttgatttc gacttcgata tccagatttt caaatgcttc tgcaacaata tcggcgattt
    52981 cttcagtgtt tcctgtcatg ctagcatata cgatttttgc taaagccatg atgtgcctcc
    53041 tcgtttataa ttatttaaca attatgaatt ataccaaaac atcattgaaa agaaaataaa
    53101 acctagagac acctggggaa tgtcatttgg ctaaatgtat gccgctatgt taaaatgaga
    53161 gggatttgta aaaaggagac gaaaatatga ttactttaaa atcagcacgt gaaattgaaa
    53221 tgatggcaga atctggagct ttattagcag atgtacataa aaatctgcgt gattttataa
    53281 aaccaggaat cacaagttgg gatattgagg tatttgtcag aaactatatc gagagtcatg
    53341 gcggaattgc tgcgcaaatt ggctttgaag ggtatgaata tgcgacttgt atcagtataa
    53401 atgatgaaat ttgtcatgga ttccctcgta aaaagccttt gaaaaacggt gatttggtaa
    53461 aagtcgatat gtgtatcgat ttgaaaggcg gcatttctga ttcttgttgg gcctatgtag
    53521 ttggagaatc tacacctgag atcgaccgat tgatggaagt aacgaagaaa gctttgtaca
    53581 tcggtattga gcaagcacaa gtagggaatc ggattggtga catcggtcat gctatccaaa
    53641 cttatgtaga aggcgaaaat ctagcgatcg ttcgtgattt tattggtcat ggcgttggtc
    53701 ctacgattca tgaagaacca gcagttcctc attacggaga agctggaaaa gggttgcggt
    53761 tgaaagaagg catggttatc acgatcgaac ctatggttaa taccggaact tggaaaatga
    53821 aaatggatcc taacggctgg actgcgtata caagagacgg cggactttct tgccaatatg
    53881 aacatacatt ggctattact aaagatggtc caagaatttt gacatcacaa ggagaagaag
    53941 gcacttattg atctatccag tcaataggta cgggagaggt acatgaaagt ttggaacaaa
    54001 ataaaacaaa atgaaaatct gatgcgcttt attgagacga ctcaaaagcg catcactgat
    54061 tcagaaatga gtacgacctc tgtcgtcgtt gcttattatt tactcttgtc tttatttcca
    54121 ttgattattg cttttggtaa tattttaccg tttctccaca tcgatcaaga gactgtactg
    54181 acctatttac gagaagtgat tcctgagacc gtttaccagt ttatcggtcc tgcaatcaaa
    54241 gaccttttga cacaaagttc aggaggcttg ttatccgttt ctgcattagc ggctttatgg
    54301 tctgcaagtc aaagtatcaa tgctttgcaa attgcgatga ataaagcgta tggcgtagaa
    54361 aatagaaaaa attttttgat cgtccgtttc ttctcactaa ttgtcattgt cttgttcatg
    54421 attgctatta gtggggtaac tatcgttctt gggttgggac agctgatttt ggatgctatt
    54481 cagccaatcg tacaaatacc cgtgaacttt atcgatcagt tccaaacttt gaagtggcca
    54541 atcacattgg tagctttatt tgtcatcatg ttcttgattt atttaattgt ccctaatgct
    54601 cagttgaagt tgaagacgat cattccgggc acgatcttcg ctactgtcgg ctggatgctg
    54661 ttatcacaag tgtttagtat ctatgctagg tattttgcaa cgaggatcag cggttatcag
    54721 atcataggaa gttttattgt actcatgctt tggcttaatt ttgctgctac gatcatcatt
    54781 ttgggcggaa tcatcaatgc agttgttcaa gaatacgtga cgggtcatca aatcaaaaaa
    54841 cgtcgagatc caagccgaaa atggttcaat aaattgaaaa ctaaattttc tcataaaaaa
    54901 aagtagaaac aagagttctt attgtaaatt tatatcagta atttataata attatgactc
    54961 ttaattaaag taggtgccca tatgcttgtt tcttttagta tggttataag attttttctg
    55021 acaattttat tatcactgat attaacacct gtattcaaaa tcatttcagt acaaacaggt
    55081 atggtcgaca aaccaaatga aagaagaata aataaagttc caatgccttc agcgggcgga
    55141 ctgcctatct ttatttcatt tgttatatcg actttattct tattccgtaa aattatccct
    55201 caatcgtata ttgtaccgat cttgattgct tctttagtaa tcatagtcac aggagtgctc
    55261 gatgataaat atgagctgac acctaaacaa aaaagtatag ggatcttgat tgcttctctt
    55321 attatttatt ttgtagcaga tatacgtatt gattccttca cgcttccttt tattggatat
    55381 atccaactag gctggcttag ttttcccgta acgatttttt ggatcttcgg tatcacgaat
    55441 gcggtcaatc tgattgacgg tttggatggg ctggcggcag ggatttcatt gatcggttta
    55501 attacgatag gaatcattgg atattttttc ctccatgctt ctacagtgta tattccagtt
    55561 gttattttct gtcttgtagc aagtattatc ggtttttttc cttacaattt ttatccggca
    55621 aagatttatt taggcgatac aggagctcta ttcctagggt ttatgatggc cgtcctttca
    55681 ctacaagggc tgaagaacgt gacttttgtt tcatcgattt ctttgctgat cgtcatggga
    55741 gtgccggtaa cagacacgtt ttttgctatc attaggagaa aagcaaaccg tgtttctttt
    55801 tctacagcag ataaaaaaca tcttcatcac cgactaatca gtttaggctt tactcataaa
    55861 ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt ctttcacagc tatggtcatg
    55921 aattatactg gaagaatcgg aacgatcata ttgattattg ccatgttgtt tgctgcaatt
    55981 ttattatttg aattgattgg tctgatcaat gagaaacatc agtttatttt aaaaacattg
    56041 cgatttttag ggaataaaga gtaccgtacg caagtaaaac agaaatattt gaagaaatgg
    56101 aaccgtcata tagatgaata acaaattaaa ccagccgatc cttattagta ttgtgacggc
    56161 aaacagtgat aaaatttttc ggacactaga taattttatt tcaactgtaa aagatgaaac
    56221 agcagtaaaa atccgaattt ttgacaacaa ttcacttccc gagtacaaaa aaagactaac
    56281 agagtatagg aaatatccct acatcgatat ctattttcat gatgaaaatt ccggatttgg
    56341 ttatggacat aatcacaatc tgatagctag cgattctcgc tatggcatta tttgtaaccc
    56401 agatatttta gtggatgaag agacagttac agcattggtc ttgttattga aagaacatcc
    56461 ggaatgtgcg atgttagcac ctaagattct taatgaagat ggaacaactc agcacctcat
    56521 ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt gtgcctttca aatgggtcaa
    56581 aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga ggattgccta ctgatgctaa
    56641 tagttatgta cggatgatct caggtagttt tatggtagct gatattgata aatttaaaga
    56701 gataaagggg tttgatgagc gtttcttcat gtactttgaa gacaacgact tgtgtttgag
    56761 ttttgaaaaa gcaggttaca agttattgta cacacccttt tatgcagtta tccattttta
    56821 cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg tttttgactt ctatgatgaa
    56881 atttttcaat aagtgggggt ggcgtttttt ctgatgaaac cagaaatatt agtagtcgtt
    56941 gtgctttatc agcaactatt cagtcaatct ccagcttatg gaccattaag caaagcactt
    57001 agcgaaaagc aaattcagct tattatttac gataatagtc ctcaaaggca gcaaaatgag
    57061 ctgtttgaaa aagaaaatat cgtttatcat catgatccgc aaaatcctgg tttagcggtg
    57121 gcttataatt ttgcgttgtc tcaagcagat gaaggaacac gttgtctcgt cactctggat
    57181 caggatacga ggctagtcga cgattatttt gaactattgc gtaaagtaac ctttacagat
    57241 gaatgtgttg ctgcagttcc gatgattttt tctgggagcc gacaagtttc tcccctatat
    57301 tcagatcgtt atatcaatcg tacagctcaa gcagtagaag ttgaaggccc aacagctgaa
    57361 cgaatcatgg caatcaattc aggtgttgcc tggtctgtca aatttctaaa aaagattggc
    57421 gggtttaatc ctgctttttc tttagatttt ttggatcatt ggctgttttg gaaagtggat
    57481 cagttggaaa aaactgtgga gatccttcct gtacgaatgg aacatgatct ttcggtttta
    57541 gactatgaaa aagtttcaag taatcgatac cgttctattt tacaagcaga aaatcgattt
    57601 tatcatgaat atgatcaaag gcatttatcc agtcaccgac gacaattatt gttaagaaca
    57661 gctaaacagt tcttgaccgt caaaaaccgg catatctggc ggatgacttt gcgctcatat
    57721 gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt atagctacct ttaatggagg
    57781 cagatattta agagagcagt tagatagtat tttatctcag ctttcagcag aagatgaagt
    57841 agtcatttct gatgatgggt cagtagatga tacatgggat atattaactg aatacgcaga
    57901 aaaagataag cgaatccagc ttttttcggg gcctcgtcaa ggattgatcg ctaattttgg
    57961 ttatgcgatc cagcagacga aaggagatct aatctttttg gcagaccaag atgatgtttg
    58021 gttggagaca aaagtgaaaa agatcactga ctattttgag cagaatccgg atcagctagt
    58081 agtagtttct gatttaatca ttgtggacag cgagctgcaa gagatccatg attcgtattt
    58141 ttcgtttcga aattccaaag aaggatggct taataatgtg ataagaagtc actatattgg
    58201 tgctggtatg gctttccggt cttctttaaa acccgatatt ttgccgatcc cgtcagaagt
    58261 gccgatgcat gatatgtgga ttggtttgct gggaggaaag aagactgggt tcctaagaga
    58321 accgttaact ctgtaccgaa gacatgattt aaacgcgagt gagattgaaa cacattctaa
    58381 attacggcaa aaaatttctt ggcgtgttca tctgattacg gcgttgatca aacgaaaatg
    58441 gtttaaacgt tgataaaaga tgtttaaatc cttaatattt ccatgacaaa tataacaatt
    58501 gatgagataa taacaaagtg aaatttgaaa tcaaaaagga gagcagatat ccatgaaggg
    58561 aatcattctt gctgggggca gcggaacacg tctgtaccct ttaacaaagg caacatcgaa
    58621 acaattgatg ccgatttatg acaaaccaat gatttattat ccaatgtcta ctctgatgtt
    58681 ggcgggaatc aaagaaattc tgattatttc aacgccacaa gatacaccac gtttcaagga
    58741 attatttgga aacggaaatg atttaggact gcagatcgaa tatgcagtac aagaaagtcc
    58801 agatggattg gcacaagcgt ttatcattgg agaagaattt attggagatg atagtgtctg
    58861 cttggtatta ggggacaata tttactatgg tggcggtctg tctaaaatgt tgcaacgagc
    58921 agcttcaaaa gatacaggcg cgacagtatt tggctatcat gtcaatgatc cagaacgctt
    58981 tggtgtagta gaatttgatg agaatatgca agctttgtcg attgaagaaa agcctgctca
    59041 gccaaaatca aattacgctg taactggcct ttatttttat gacaatgagg taatttctat
    59101 cgctaaaggt atcaaacctt cagaacgtgg agaactagag attacggatg tcaataaagc
    59161 atatttggat aaaggaaaac tatccgtaga acttatggga cgcggatttg cttggcttga
    59221 tacaggaaca catgaatcat tgcttgaagc atctaccttt atcgaaacaa ttgaaaaacg
    59281 tcagaactta aaagtggctt gtttggaaga aattgcttac cgtatgggct acatcgataa
    59341 ggaacaattg ctggcccttg cacagccatt gaaaaaaaat caatacggtc aatatttatt
    59401 gaatttggcc gctgaataag gagtccttac agatgaaagt aacagataca aaattaacag
    59461 atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg cggtttcttc acagaaagtt
    59521 attcaaaagc aaaatttgca gaacatggat tgaaatatga ctttgttcaa gacaaccatt
    59581 cactatcagc tgaagctggt gtccttcggg ggcttcattt ccaaaaagga gaagctgcac
    59641 agacaaaatt gattcgggta gtcactggag cagttttaga tgtagtagtg gatatccgca
    59701 aaggtagccc gacttatggt caatgggacg gatttatctt atctgaacat aatcatcgac
    59761 agttgcttgt acctaaagga tatgcccatg gattcgttac tttgacacca aatgtgaact
    59821 tcctttataa gtgtgataat tactataatg cagaagcaga tgggggcatc gcatttgatg
    59881 atccagattt agcgattgat tggccaattg atccatcaag agcgattatg tcggaaaaag
    59941 atcaccgtca tccgacatta aaagaatttg aagcagaaaa tccatttgtt tacggagaaa
    60001 tctaagaatt aaggagaaat tttcttatga aaaacatcat tgttaccgga ggtgccggat
    60061 tcatcggctc taatttcgtt cattacgtgg taaacaatca tccagaagtg catgtcactg
    60121 ttttggataa actgacttat gcaggaaaca aagagaactt ggctggactt cctagcgatc
    60181 gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt agtggaccgt ctagtaaaag
    60241 aagcggacgc agttgttcat tacgcggcag aatcccataa cgataattca ttaaaagatc
    60301 ctttcccatt tgtacaaacg aatatcattg gtacgtatac acttttagaa gcttgccgca
    60361 agtatgatgt acgctatcat cacgtatcta ctgacgaggt ttacggcgat cttccattac
    60421 gtgaagacct gccaggacat ggggaaggcg aaggagaaaa attcactgcg gaaacaccat
    60481 ataatccttc aagtccatat tcttctacaa aagctggttc agatctgtta gtaaaagcat
    60541 gggtgcgttc ttttggctta cgtgcaacca tttcaaactg ttcaaacaac tatggtcctt
    60601 atcagcatat tgaaaaattt attcctcgcc aagtaacgaa tatcttaagc ggtattcgtc
    60661 caaaattata tggcgaagga aagaatgttc gtgactggat ccatacgaat gatcattctt
    60721 cagcagtgtg gctgattttg acgaaaggca gaattggcga aacctatctg atcggtgcag
    60781 acggtgaaga agataataag accgtgatgg aattgatctt agaaatgatg ggtcaaccaa
    60841 aagatgcgta cgaccatgta aacgaccgtg caggacacga cttgcgttat gcaatcgatt
    60901 cgacaaaatt acgggaagag ttaggatgga agcctgagtt tacgaacttc cgtgatgggt
    60961 tggctgacac gatcaaatgg tacgaagaac atgaagactg gtggaaaaaa gaaaaagagg
    61021 ccgttgaagc agcatatgcc aaaaatggac aataatacag agaaaatgtc actgtattaa
    61081 tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt tttaaaataa aaatcaagga
    61141 gcggataatc atatgttttt attaactgga ggaaatgggc aactaggtac agaattgcgc
    61201 catttattag atgaaaaaaa tctgcaatat gtttcaacag atgcaaaaga cttggatatc
    61261 acagatgccg agaaaacaat ggcttacatc acagaattaa aacctgatgt tattttccat
    61321 tgtgcagctt acacagcagt agataaagca gaagaagaag caaaagaatt agatgagaag
    61381 atcaatgttg atggtacaag aaatgtagca cttgcagcaa aagctgtgaa tgctcaattc
    61441 gtctatatca gtacagacta tgttttcgat ggaaaaaaca aaaatgtaga atacgaagta
    61501 gacgaccaaa cgaatccact aaatgaatat ggtcgtacga aattattagg cgaaaaagca
    61561 gtagaagaga ttttagaaga ctattatatc atacgaactt cttgggtttt cgggatctat
    61621 ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa cccgcgacaa actgactgta
    61681 gtaaatgacc agtttgggcg accaacttgg acacgtactt tggcagaatt tatggtatat
    61741 gtcatcgaag aaaaagcacc atttggtatt tatcatttgt cgaacgaaaa tagctgttct
    61801 tggtatgaat tcgcaaaaga aatattgaaa gatacagatg tagaagttgc acctgttacg
    61861 tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt cagtcatgag cctgaaaaag
    61921 acagaagagt taggatttgt cataccaact tggcaagaag cacttgcgca aatgctggaa
    61981 gctgccaaaa aaatgaataa gtaatttcct tttatcaaat agaatttgga gcatgatatg
    62041 gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa aagcgaacca ggcagattcg
    62101 aatttggtgc ttgacctgtt tctaaaactc cgctatctta ttggcgtttt agtcatcgtg
    62161 gtcatcgtta cttttaattt aaacggaagt tcacttggtg tttgggataa atatgtgtcg
    62221 caaagagacg atgggaaaaa aactgatgtg atttttggac agaatcggga agtgcggtca
    62281 gacgaatggc tggtgcagac acctttttac ctctcacaag ctgaagagga ctttccgttg
    62341 gtgaacgagg attattcatt aaacggacaa aacatgatca ttgcgtataa ttctcctgca
    62401 aaggatatta cggttatcgg aaaaccattc aactggggat tctttttcct cggaagagat
    62461 cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca tggtcttgct tggattcgaa
    62521 gtactgatga tattaacgaa gagaaaaaaa gctctatcgc taatcggtgc atttgcgctg
    62581 acattttctc cagcagtcca gtggtggttc atgcaacatg tgggcgattt gattttcttt
    62641 actttgggac tgatgactgc tttttatcat tatttctaca atcatgataa aaaatggcta
    62701 cgaacgttga tgatgctttt ggtggttatt ttcggtattg ggtttatttt agtgatttac
    62761 ccagcccatc aagtgatgct ggcgtacttg ctgatttttt attttgttgg cctgcttatt
    62821 tactatagca agaaagtttc atgggatctg ttggatgtag tgttgattgg aggggcagtt
    62881 ttatttattg gcggagtcat ggttcatttc tggctaacgt caaaagacgc attgttagct
    62941 tctttgaata ccttatatcc aggaaaacgg gtaagtactg gaggaaagtg gacgattggc
    63001 gaattttttt ctttccttac aaattggaaa attccttttg aagatatcaa ctattcgaat
    63061 aactctgaag tggccctgtt ctatcacttt tttccaactg tattcctagc aagtccattt
    63121 gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg gacgtatttt gatgattttt
    63181 tgtctgtttt ctatcttttg gattaccgtt gggttgccaa aatggctagc agaaatcact
    63241 ctgctgtctt atgttcctcc attaagagcc atccttactt ttagttttgc ggcttgttta
    63301 ttatcgatct ggtttatcgc ttatatttgg agagaagatg ttattcctat ttggtataaa
    63361 ttcattttgt tggcagtaaa tgcatggtct tatttctatg cgattacgca ttcgaaaata
    63421 gataattatt tttcggattt tgaaaccatc gcagttgctg tgttgggaac agtgatttta
    63481 gcatttgcat tatttggctg gagacgcttg ttttacctcg cttttgccgc cttagttatc
    63541 gtatctggct ttttcgtcaa tccagtcgta gaaggtacag gagcgatttt tgaaaaaaca
    63601 ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg gtaaagtttg gttgtctgaa
    63661 gatgaattat ataacttcac cccaacattg ggagtgaaat ccttcaatac agtacgcttt
    63721 tatccagata tagctgcatg gaaggaaatc gatccgaaag aagaatacga gaagtattat
    63781 aatcggtatg ctcatacaag agcttttatc gctaaggaag atacaaagtt cattttagat
    63841 cgtccagata tgttttcggt cacgttgaat tttgaagacg cagaaaaatt agggatcgac
    63901 tatgtgatca gtaaacgacc attaactgat tacaaccaat tatatgaagc gcagttcacg
    63961 cagctatatg gaccggataa agacggttat atgattttta aagtagaata tccggattat
    64021 ccagatgtac cacaaacaca aactcaggaa aatcagctag tcgtacagta ataggctagc
    64081 tgagaataat cctgaaatat tagtagaaag gagagtggag ataattcaag caatcgtaca
    64141 aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg ttgctgacgc tagtcttttt
    64201 tgtttggaca gcagggttag gttttccagc aactttgttt atatataaca atagttcatt
    64261 acttatcgct tttagtgtgg ctattttgct cattttaaat gtttataaag caaaaggcgt
    64321 cgattttctt tatctaggtg ttgcgcttgc ccttttcatt ttcttttctt actttcggga
    64381 attaagaaat gagtctttat ttggagattt actgtttcct ttgattattt tattttgttt
    64441 agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt atttatctga ttgtctttac
    64501 ggtcttcctc ggaatcacgt tatatcgtgt atttacagag atccaagtac cagaaggaca
    64561 aagcatctgg gctccaggca attcgctttc tgatatttgg atcaatacga atacaatcgg
    64621 aagttctttg atgactcttg ctttattgat cagtggattt gccagttctt ttgaacgatg
    64681 gtatgtacga atcatcggtg cagtagcagt tgttgcagct tttctcggga tttgggtctg
    64741 ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg atattggatc ttttacctaa
    64801 atcgttgatg cgtgtcattc gtgcgccatt tattgcttac acggttacga ttcttttagc
    64861 tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc aatttgttta ccggtcgaga
    64921 agatatttgg cataaattct atcagacgct aggagaaaaa tctgaacaag ttttactagg
    64981 aatgaaaaca tttatcttcc aacgaggaaa ccaattttta ggaaaccaca atagttataa
    65041 ttctattttg aatatctatg gattgatagg atttgggatt gctactttgc tgcttatcct
    65101 ttttattggt cgcttaacgt tgaaagcaga tttatccaac gggcagatga cttttatctg
    65161 ggcctttttt gcggtgatga tgcagtcatt tatggaggat acattgactt catacccatg
    65221 ggttccgatt atttatatcc tgttggctat ggccgttcat cgatatgatg aaccagaagt
    65281 tgcggaggaa ttctatgtta tggaagaggc atatgacgat atgacttatg atgatacatc
    65341 ttatgaggaa caaccagata gcgctcattc ttccaggatc caacgctatc attgataggc
    65401 acaaaat
//
LOCUS       DAJSMK010000006        65062 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.006, whole genome shotgun sequence.
ACCESSION   DAJSMK010000006 DAJSMK010000000
VERSION     DAJSMK010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.006"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(24..392)
                     /locus_tag="ON488_000395"
     CDS             complement(24..392)
                     /locus_tag="ON488_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HCR3230614.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1003..2394)
                     /locus_tag="ON488_000396"
     CDS             complement(1003..2394)
                     /locus_tag="ON488_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HCR3230615.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2607..2993)
                     /locus_tag="ON488_000397"
     CDS             complement(2607..2993)
                     /locus_tag="ON488_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HCR3230616.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3049..3672)
                     /locus_tag="ON488_000398"
     CDS             complement(3049..3672)
                     /locus_tag="ON488_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HCR3230617.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3736..4404)
                     /locus_tag="ON488_000399"
     CDS             complement(3736..4404)
                     /locus_tag="ON488_000399"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HCR3230618.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4416..4856)
                     /locus_tag="ON488_000400"
     CDS             complement(4416..4856)
                     /locus_tag="ON488_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230619.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4915..5586)
                     /locus_tag="ON488_000401"
     CDS             complement(4915..5586)
                     /locus_tag="ON488_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR3230620.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            complement(5771..6169)
                     /locus_tag="ON488_000402"
     CDS             complement(5771..6169)
                     /locus_tag="ON488_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HCR3230621.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6166..6939)
                     /locus_tag="ON488_000403"
     CDS             complement(6166..6939)
                     /locus_tag="ON488_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCR3230622.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6936..7619)
                     /locus_tag="ON488_000404"
     CDS             complement(6936..7619)
                     /locus_tag="ON488_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HCR3230623.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7786..8673)
                     /locus_tag="ON488_000405"
     CDS             complement(7786..8673)
                     /locus_tag="ON488_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3230624.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8670..9539)
                     /locus_tag="ON488_000406"
     CDS             complement(8670..9539)
                     /locus_tag="ON488_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3230625.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9676..10962)
                     /locus_tag="ON488_000407"
     CDS             complement(9676..10962)
                     /locus_tag="ON488_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3230626.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11235..11813
                     /locus_tag="ON488_000408"
     CDS             11235..11813
                     /locus_tag="ON488_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HCR3230627.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11813..12742
                     /locus_tag="ON488_000409"
     CDS             11813..12742
                     /locus_tag="ON488_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3230628.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12739..14475
                     /locus_tag="ON488_000410"
     CDS             12739..14475
                     /locus_tag="ON488_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HCR3230629.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14538..15374)
                     /gene="pheA"
                     /locus_tag="ON488_000411"
     CDS             complement(14538..15374)
                     /gene="pheA"
                     /locus_tag="ON488_000411"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HCR3230630.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15371..15880)
                     /locus_tag="ON488_000412"
     CDS             complement(15371..15880)
                     /locus_tag="ON488_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HCR3230631.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15873..17168)
                     /gene="aroA"
                     /locus_tag="ON488_000413"
     CDS             complement(15873..17168)
                     /gene="aroA"
                     /locus_tag="ON488_000413"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HCR3230632.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17181..18272)
                     /locus_tag="ON488_000414"
     CDS             complement(17181..18272)
                     /locus_tag="ON488_000414"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HCR3230633.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18289..19455)
                     /gene="aroC"
                     /locus_tag="ON488_000415"
     CDS             complement(18289..19455)
                     /gene="aroC"
                     /locus_tag="ON488_000415"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HCR3230634.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19457..20521)
                     /gene="aroB"
                     /locus_tag="ON488_000416"
     CDS             complement(19457..20521)
                     /gene="aroB"
                     /locus_tag="ON488_000416"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HCR3230635.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20554..21576)
                     /gene="aroF"
                     /locus_tag="ON488_000417"
     CDS             complement(20554..21576)
                     /gene="aroF"
                     /locus_tag="ON488_000417"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HCR3230636.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22235..23209)
                     /locus_tag="ON488_000418"
     CDS             complement(22235..23209)
                     /locus_tag="ON488_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HCR3230637.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23190..25073)
                     /locus_tag="ON488_000419"
     CDS             complement(23190..25073)
                     /locus_tag="ON488_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HCR3230638.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(25091..27316)
                     /locus_tag="ON488_000420"
     CDS             complement(25091..27316)
                     /locus_tag="ON488_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCR3230639.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27431..28465
                     /locus_tag="ON488_000421"
     CDS             27431..28465
                     /locus_tag="ON488_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3230640.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28532..29545)
                     /locus_tag="ON488_000422"
     CDS             complement(28532..29545)
                     /locus_tag="ON488_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3230641.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29623..29811)
                     /locus_tag="ON488_000423"
     CDS             complement(29623..29811)
                     /locus_tag="ON488_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HCR3230642.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30251..30379)
                     /locus_tag="ON488_000424"
     CDS             complement(30251..30379)
                     /locus_tag="ON488_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCR3230643.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30382..31755)
                     /gene="rlmD"
                     /locus_tag="ON488_000425"
     CDS             complement(30382..31755)
                     /gene="rlmD"
                     /locus_tag="ON488_000425"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCR3230644.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31866..32921)
                     /locus_tag="ON488_000426"
     CDS             complement(31866..32921)
                     /locus_tag="ON488_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCR3230645.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32931..34361)
                     /gene="gatB"
                     /locus_tag="ON488_000427"
     CDS             complement(32931..34361)
                     /gene="gatB"
                     /locus_tag="ON488_000427"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HCR3230646.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34358..35830)
                     /gene="gatA"
                     /locus_tag="ON488_000428"
     CDS             complement(34358..35830)
                     /gene="gatA"
                     /locus_tag="ON488_000428"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HCR3230647.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35830..36135)
                     /gene="gatC"
                     /locus_tag="ON488_000429"
     CDS             complement(35830..36135)
                     /gene="gatC"
                     /locus_tag="ON488_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HCR3230648.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36241..38277)
                     /gene="ligA"
                     /locus_tag="ON488_000430"
     CDS             complement(36241..38277)
                     /gene="ligA"
                     /locus_tag="ON488_000430"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HCR3230649.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38294..40528)
                     /gene="pcrA"
                     /locus_tag="ON488_000431"
     CDS             complement(38294..40528)
                     /gene="pcrA"
                     /locus_tag="ON488_000431"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HCR3230650.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40683..42242
                     /locus_tag="ON488_000432"
     CDS             40683..42242
                     /locus_tag="ON488_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HCR3230651.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(42353..44284)
                     /locus_tag="ON488_000433"
     CDS             complement(42353..44284)
                     /locus_tag="ON488_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR3230652.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(44302..45216)
                     /gene="pfkB"
                     /locus_tag="ON488_000434"
     CDS             complement(44302..45216)
                     /gene="pfkB"
                     /locus_tag="ON488_000434"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HCR3230653.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(45213..45965)
                     /locus_tag="ON488_000435"
     CDS             complement(45213..45965)
                     /locus_tag="ON488_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR3230654.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(46125..46334)
                     /locus_tag="ON488_000436"
     CDS             complement(46125..46334)
                     /locus_tag="ON488_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230655.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(46345..47673)
                     /locus_tag="ON488_000437"
     CDS             complement(46345..47673)
                     /locus_tag="ON488_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230656.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47809..47964
                     /locus_tag="ON488_000438"
     CDS             47809..47964
                     /locus_tag="ON488_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230657.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(48038..48625)
                     /locus_tag="ON488_000439"
     CDS             complement(48038..48625)
                     /locus_tag="ON488_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HCR3230658.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48708..49958)
                     /gene="clpX"
                     /locus_tag="ON488_000440"
     CDS             complement(48708..49958)
                     /gene="clpX"
                     /locus_tag="ON488_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HCR3230659.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(50205..51494)
                     /locus_tag="ON488_000441"
     CDS             complement(50205..51494)
                     /locus_tag="ON488_000441"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HCR3230660.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51648..52580)
                     /locus_tag="ON488_000442"
     CDS             complement(51648..52580)
                     /locus_tag="ON488_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230661.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52737..53396)
                     /locus_tag="ON488_000443"
     CDS             complement(52737..53396)
                     /locus_tag="ON488_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCR3230662.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(53399..54424)
                     /gene="sppA"
                     /locus_tag="ON488_000444"
     CDS             complement(53399..54424)
                     /gene="sppA"
                     /locus_tag="ON488_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HCR3230663.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54437..54727)
                     /locus_tag="ON488_000445"
     CDS             complement(54437..54727)
                     /locus_tag="ON488_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230664.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            55136..56941
                     /gene="glmS"
                     /locus_tag="ON488_000446"
     CDS             55136..56941
                     /gene="glmS"
                     /locus_tag="ON488_000446"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HCR3230665.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(57013..58368)
                     /locus_tag="ON488_000447"
     CDS             complement(57013..58368)
                     /locus_tag="ON488_000447"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HCR3230666.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(58392..59561)
                     /locus_tag="ON488_000448"
     CDS             complement(58392..59561)
                     /locus_tag="ON488_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230667.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59558..60445)
                     /locus_tag="ON488_000449"
     CDS             complement(59558..60445)
                     /locus_tag="ON488_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HCR3230668.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60634..64326)
                     /gene="nifJ"
                     /locus_tag="ON488_000450"
     CDS             complement(60634..64326)
                     /gene="nifJ"
                     /locus_tag="ON488_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HCR3230669.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64525..65046
                     /locus_tag="ON488_000451"
     CDS             64525..65046
                     /locus_tag="ON488_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCR3230670.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT        18103 a        14098 c        11604 g        21257 t
ORIGIN      
        1 gaaaaacaaa gtctttattt ctattattta cctgtaaccg caaagtagtt gccatcggga
       61 tcagcaaagt taaagacata ttcttctcca agctgtacca tatcacctaa tgtgactgat
      121 tgcgtctgca tttttttata tagtccaaag atatctttac tgtaaaacat caaagatggg
      181 gcactagtag ctgtgccagg tgaatgggac tcaacaaatg ctcgatcata taacagaaat
      241 gaggtttgac tgtcctcaac tcctacttca attataagcg tcccatccat ttcttgacga
      301 tctttttccg caaagccaac tgctctccaa aacgttgcat ttttttctac atcgtccaca
      361 taaagcatga tttttatttc attcgtaaac atctgtttcc tcctaaacga tctgttctaa
      421 cattctcaac tttgtcagtt taccatagga aaatgggaaa atctacgaaa gctctcaaca
      481 gaatcgtcct acttaaatac gcttttcttt aataataaat aagttggttg tttttgttat
      541 ttgcgctttc acttttcgga ataaataatg tgtatttata tggaataaat aaaaaaagag
      601 gtcgtgacta aaaacaagtc acaacctctg gtaaacggtg ttctcctgac aactcctcgg
      661 tcacaagaca caatattcaa caaacatgag aagctatttt ttgaaattgc tctttgtgac
      721 tcagagtgaa acggcaggct cacgacctct ttcttaaacg gtgttcaaaa gcttgcatct
      781 gcggtaataa gctcaaccaa acgtaaaata tgaggaacta tttttgtttg gctgttctta
      841 ttacttgatg cagggcagct ttttcacaac ctcttattca cggtgtttca gaagtagctt
      901 ctcggaaata agccgaaatt tcacaaaaat ttgagaaact atttttagga aacttcttct
      961 tatttcttaa agctgaccac ttctatcaca acctcttttt gactatgcat tcacatcgat
     1021 cactttagaa tcatcattga tgacatcgcg atctaaatct ttgatgcgtg cacttgtcac
     1081 gataccagct accatgctac cgctgacgtt tactgctgta cgtgccatat cgattaatgg
     1141 ttcaacagag ataactaacc caacgattgc tactggcaag ttcattgccc ctaaaacgat
     1201 cagtgaagca aatgttgcgc ccccaccgac tccagctaca ccaaaagaac tgattgttac
     1261 aattgccaca agcatcaaaa taaattccaa actaaagaca ttcactccag ctgctggtgc
     1321 gacgatcgtt gccaacatag ctggataaac gccagcacag ccgttttgtc caatagacaa
     1381 accaaaactt gctgagaaat tagctgttgc atcatctact cctaaagctt ttgtctgagt
     1441 ctcgatattc aatggcaaag ctccagcact tgaacgtgaa gtaaacgcaa agctcaatac
     1501 cggaaaggct tttttgaaat agttgattgg attgactttt gcaccaatca aaatcagtga
     1561 gtggacaatc aaaacagcaa gcaatgctac gtaagaagca acgacaaatt tacctaaatt
     1621 gacgatagct gcaaaatcac ttgttgccaa aacgtttgtc atcaaagcaa atactccata
     1681 aggtgtcaaa cgcaaaacaa gcgtcacgat ccgcataatg attttataca gactgtcgac
     1741 taaatctgaa aagaatgctg cttcttttgg cgcttttctt ttcacgccta gataagcgat
     1801 tccgacaaat gccgcgaaaa taacgactcc aatcgtactt gttgcacgac tacctgctaa
     1861 atcagcaaaa acgtttttag ggataaagga taaaatctgc tgtggaatcg ataagttttc
     1921 aactgtttcc tgacgtgttg ccagttcaga gattcgtgct gtttctgcag ctccttgtgt
     1981 gaatttagct ccttggagtc cgaacagcat tgttgaacca attccgatca atgctgcaat
     2041 agctgttgtt ccaagtaaag aagtcaatac agtcgcacta attttcccta gcttttcaga
     2101 aactttcatt tttgtgaatg caccaatgat cgaaataaac actaaaggca taactagcat
     2161 ttgcaagaat gatacatatc cttgacctac aatcccgatc cattccattg attgagtaac
     2221 gactttgtcg tctacaccaa agatcaattg aagcagaccg ccaaagacga taccaactcc
     2281 taatgctgta aagacgcgtg ttgaaaattt tgtatggcgc ttttgcatac gatagaacac
     2341 atataataat gccgcaaaaa ctagaaccac taaaactgtg atgagtgttg tcatttttct
     2401 cctcctcata ttattaatga caagtccatc gaaggaagta aaggttcccg agaatgattc
     2461 ttcaaccatc ctcctgaaaa aatttttttc agtgactttt atattttaga cgatttttat
     2521 cgaaatgaca ttctttttgc ttacaattag taataaaaaa acatacctgt gatagcttta
     2581 atctatcgca ggtatgtttt tactgtctat tcttgttttt ctgattgaaa attcaatttt
     2641 accccaggct gatctaaggc gatctctgtc acctcataag acattcggcg tacgatatcg
     2701 aataacggtg ctactagctc gtccacttct tcttgtgtga catcattttg accttcaatt
     2761 ttccgattga ggatatgatt gatctgactc acacttccag ataaaacata tgtatcaaac
     2821 actaaacgga actctaagcg tgctcctacg atgctatgtt ctttcggata gttttcgatc
     2881 gtttctttta aaggcgagaa gcctactttc aaatctgttt ctacttcttg gttcggcaat
     2941 ctcatatcat aatgaaatgc ttctacaact tctttttgtc ttctgatttc catataattt
     3001 tatcactcct ttatgaaaat tataacatat ctcctttgaa aggggatact actttttaat
     3061 gatgctctgc aaggtaagga tttcattcag atttcctacc acataatctg ccgggatctc
     3121 acccagaaaa tgatcgatgt cgtaaagaca agtagcgact cctgcatttt tccctgcttc
     3181 gatatctaaa cgacgatcgc cgatcatcat cgtgtctgtt ctttctaaat gaaaagtatc
     3241 gatcaaataa tttaaagatg ctggatcagg tttacgagga aagtcctgat cgatccctac
     3301 tacttcctca atcagatgtg ccaatcgatg ttcttttaac aggccccatg ttgattctgt
     3361 caaacggtgg gtcaggatga aatgacgacc gccgttgtct tttagcattt ccagtacttg
     3421 tttcgtttct ggaaatggac gggaaacttc cgtactttct ttttcatatc ggtgaaataa
     3481 ttcattaaac tctctggcat tcaagtttga ttcattgatc aaataactag tagaatactt
     3541 tttcattttg aagtagattt cttttttgtc catactgata ccaaaatctt ttagtgcttg
     3601 ccatgcacca tctaccattg cgggatacgt atcaaacaat gtaccatcaa agtcccatat
     3661 ataatttttc atgttccttt tgttccattc ctttgcttct tttttctatc tctcactttt
     3721 agataaaggt gttctttaaa gtattttttt gtccagaatt gtcaaatcat ctgctaatgt
     3781 atactggatt ggttgtgcat ttgggatatc gatcgtatcc atttgatctt caggaacatc
     3841 ttctaaatat tttgtcagtg ctcggatgct attaccatga cccacaacta gtaaatcttg
     3901 ccgatctttt agttttggtg ctagatgatc ttgccataag ggaatgatcc gattcactgt
     3961 catttccaga ctttctccgt atgggatcaa atgcggatcc aagtgatcat atctgcggtc
     4021 aaatctattt tctgcggtta acggcggaac ttccgtatat cctctgcgcc atgtttttac
     4081 ttgatctttt ccgtatattt ctttcatctt atctttgttt ttacccacaa gatccccata
     4141 atgccgttca tttagacgcc atgtttttat tataggaagc cataactgac ccatttcttc
     4201 tagtgcgact tgtccggtaa gaatcgcacg tttcaaaaca gaggtataaa cggcatcgaa
     4261 ttgaagtccg gcttcaagca ttttttgacc ggcaactgct gcttgttctt ttcctttttc
     4321 tgttaaggcg acatctagcc atcctgtcca gtaattttca aaatttgctt cgctttcgcc
     4381 atgacgtaat aatactaatt tcattctttt ctcccttaaa cattcgtttc gaattttata
     4441 ccacatgttt tgcatgtcac acgtattcgt ccttttcctt taggtgcacg ctgcttttga
     4501 tgacaattcg ggcactcaaa aaaagtataa ctttttcgat ccattttgac ttgctttttg
     4561 ttttttatct gatgatattt ttctttgact ctatcaagat atttcaaata acgttgattc
     4621 tcatttagtc tggggtagat tttttttgat aggaaacgaa atatcatcca tccgaaaaag
     4681 acgatgaaca acaattgtcc gattctatag ggcaaccaac gacttagcaa actaaagaca
     4741 agcgcagcga tcaatagacc gcgattcaac tgatcaaatt tcgcatatct tccctgcata
     4801 agtttgtgat agttctgctg aaatcgtatt agcctttcta accatgtttg catcatatta
     4861 tctcctccat catctaatat ttattatgac aaaaaaatcc aaaaagaaaa agccttaatt
     4921 ggccttttcc attgcaactt ggtgaaggac attccgattt ctggtaaagt caatcacaat
     4981 cactttcttt ttatcttctc tgttgactac tcgaaatgtg tccgtcaatg gaagaaacag
     5041 cttcttagat ggtagctgtt gcatacgtat aaaacgatgg atcatcgtaa tcaattgagg
     5101 aaattgaata gacgtgtgaa gcagacctgg atattttttc aacagctgtg tcgttttgat
     5161 cagattccgt tttttactga tcacttttaa aaagcttttt agaatctttt gctgacgtct
     5221 aaaaatagaa aaagaatttt cgtcatctat ttgataacgc atttgttttt gcagttctgc
     5281 tgcagtcaga tggatcttcc catcgtttgt atcgatcatt aaaccttctg gaaacagttc
     5341 aaccactgct cgatcccaag attcaagaga aagctcgata taatctttta ctggtaattc
     5401 caattctacc ttaaaaaagt gcaaaacagc cgacagccct tctgcttgat agatttctcc
     5461 taatgttagc ccctctagat ggaactctgg tgaaaaatgc agcaatgttt tattttcctg
     5521 caattgaaca tatagaaatg tagatcgctc aatcagagta tcttttaaaa caactaaaaa
     5581 attcattttt ctcccccttt tttcatcatt tttaaaatag catattttga aaagaaagtc
     5641 tgatgcttag agtagaattt cataaaaatt tactatttca taagtattca cgagaaaaat
     5701 acaaacaaaa aagcggaaat aacgctcatc cgccttcttg tttgtgttta tttcctcttc
     5761 aaacgcttgt ctatgattca gacttttctc tatcgttatt ttcatctaaa agttcttgca
     5821 ttccgataat ttctcgatat tgatgaatct tagtgatacc aatgactttg tctacatcaa
     5881 tactaaaaca aataccatta cctggaatat cgatgttgat gccttgacca atcgcatcca
     5941 ttactttatt cgtcaaacta tcgggtacta atgtcaacac aatatctttt tctggcgaaa
     6001 tgtccaaacc taaaaatttc cctgaatcat gtacaccaga acctcttcca tgtaagatcg
     6061 ttccgcctgc tgcacctgct tcttttgaaa agtcgataac atcttcgccc attcctccgt
     6121 caacgatcgt cacaatcatg tgaagattca atgctacaag atctttcatt tgctttcccc
     6181 caatttttgc aatctttctt tttcgattct gtctttttca tcttttcgtt tataaatata
     6241 tcctagtact aaagtggata atattggtgt caatgcaatc attgcaacca caccaaaccc
     6301 gtcaatgatc ggatctcttc cttcaatttg tgcagcgatt gccacgctca ttgataaaat
     6361 aaatgtcgaa cacatcgggc ccgttgctac tccaccgtta tcaaaagcca ttgctaaaaa
     6421 gatcttgtcc acttttcgtc ctaaaataaa tgctagcccg tatcctggga tcaagaaata
     6481 ataaagagag aatccgacga gcaaacgcca catagacaat cctactgctg cgccgatccc
     6541 aattgaaatt accatcagca tgattttcga tcggattctc ccctcgctca attcttcaac
     6601 ctgtttgatc attacatgaa tcgccggctc agcaaaccct actaagaacc ccattaaaaa
     6661 gccaagggga accagtatat aattgtaagg caatcccgca atagcactgc ctaaatgctg
     6721 tcctaccggt acataagcca tattgactcc gtgcaggaaa aggatcaacc caatagtcgt
     6781 tatcaagaaa cctttcataa tgtcaaagaa acgctttttg cgcatacgaa aactaatgat
     6841 attcattaaa acaaatagga ttacgatagg tgccactgcc aaaatgactt ccatggtaac
     6901 gatttcgatt ccatctatca cttgctgcca gaaactcatt ggaagatcac ccccaaaatc
     6961 atcacggcaa gaatcggccc taacgaagca ataccgacca ttccaaaact gtcattttca
     7021 tttttctttt gtttgatcat actagtcatc cctccggcaa gggccaagat aaatggaaca
     7081 gttactggac cagtagtcac tccccccgaa tcaaaagcaa tcggcataaa ttcggaactg
     7141 gtgaaaaatg aggcgatcaa aacgcctatg tagcctatag ccatcaattg ataataggat
     7201 agcttgaata cgacccgaag cagcgcaaag gctagaaata ctccagtgcc gacgctgacg
     7261 atcccaatca gcaacactct gccaatctct ccgtcagata tatcatatac ttgttgtccc
     7321 aaaacttgca cggaaggttc agcaatcgtg atcacgatcc cgatagcaaa tcccaaactg
     7381 accaaaacgg tcaaactttt ctttttgatc atatatttcc ctactagatc tccgacttcc
     7441 atcatagaat aatctgctcc aaacaaaaag agcgtcattc cgatcatcat gattgccgca
     7501 ccaaccagaa atgaagcgag gtcttctcct tctaacggtg caaaaacaaa cgttaaaatg
     7561 acaatcagga cagtcatcgg caatatagca gcaatcactt ctttaaaatt ttttagcatg
     7621 tatcctcctc ctttactctt taagtttacc ttaaaatgaa agagttttcg agcacaaact
     7681 taaaacgtta tcatttaatt tttctcaaca taaaataaca cacgtcccaa aagtatcttt
     7741 ttacttggaa aaatgacttt gaaggaacgc gcttattgtg tttttttatt ttacagagcc
     7801 gatcattcct tgaacgaatt gcttttgcaa aacaaaaaat acgatggcag ttggtaaagt
     7861 agcgatgact aatccagcca tgatcattcc atagtctggt gtataggaag cacccatagc
     7921 agataaaaca agcggaaccg tccgtttatc aggagattgc aaagctacta agggccataa
     7981 ataattgttc cagctactca tgaatgtgat gattgcagcc gcggcatagg tatttttagc
     8041 cgtcggcata tacactctaa aaaaaatact tagttctttt agaccgtcta atcgagcggc
     8101 ttctactaga tcttttggaa aagatttaac attttgtcga aagaagaaga tcaaaaaagc
     8161 agtgctaaca gatggcagga tgacaaccaa gaaactgttg attcccaaaa ccgttccgtt
     8221 caattgtgaa aacattcgat ataaagggat catcaatgcc gcaaaaggaa ccatcatcga
     8281 tagcagtaga atattgaaaa ttaggtcttt tcgtttactt tgataaatct caaatccata
     8341 tcctgccatt gacgaaatca gcaatgcaaa cacagtggtc accaaagcga tcatcgctga
     8401 attccaaagg gaacgagtaa aattcagctc attggaaaac aaattttgaa aattgatgat
     8461 caagttactg ccaatcttta tttttcccga tgtgatatcc acgggtgtat tcgtcattcc
     8521 caaaaccatc cagacaaaag ggaaaatgga aataaatgat aggatgctta atgctgtata
     8581 ctttaatact gacccaattg tcgaacgaag ttctaatgct tgttttttga cgttggggcg
     8641 ttcgattgtt tctttttcta ccatattttt catcgacttt ctcctcctac tttcgtttgg
     8701 attatcgaca atatcacaat aaaggaaaca ataacaaagg aaactgctgc cgcatatcca
     8761 aaattaggcg tgaatttata actcaaatta tagatgtatt gagatagggt ggtcgttgca
     8821 tttgctggtc ccccgccagt aatattttgt acttcatcaa aaagctgcaa tgtcccgatc
     8881 gtcgaagtaa tggaagtaaa caaaatgatt ggttttaaat ttgggatcgt cactttgata
     8941 aactgctgcc atttagaagc accgtcaata gatgctgctt cataaatctc cgaatcaata
     9001 ttttgcatgc ctgaaaggaa aaaaatcata ttgtatccag tccaacgcca agtgatcgaa
     9061 agaatgatca gaactctcgc ccaaattgga tgagtcaacc agccaatcgg tgtgtcaatc
     9121 ataccaatgc ccaacaacaa gttgtttaca aggccagatt gagaaaatag acttttcatg
     9181 atcagagaat aactgaccat cgaagtgata catggaagaa agatagcggt tcgaaacaac
     9241 cctttatatt tcaacttttt atcatttaaa aggttggaaa taaaaagtgc tagaaacaac
     9301 atgatcggta cttgtacaag taaatacagg aatgtattaa aaaaagcttt tttaaaagtt
     9361 gcatctgtca acatccgctg ataattacct aacccgttaa atgtcatatt gacaggggga
     9421 ccactttgaa aagacgtgat caaagccaaa accatcggaa taaaaaccat gattgatatc
     9481 aaaatgactg gcaagattaa aaaagcatgc ccgtttttga ataaatcttt ctgcttcatt
     9541 cttttccctc caattctatc attgattatc tacatgaaaa gacaagaaag acaatatctg
     9601 taaggcagac gtgatctttt ttgtcttttc gtttgtctga tgaaaaagcg aagaaattca
     9661 cttttttacc accgatcaat tagccaattg tgcttctact tgtttttgtg tatctgctag
     9721 taccttgtct gtctcttctc cattgatgat tcgatgaaga gcttcagcta cgactgcttc
     9781 aattgcatag gtctcatgtc cgtaattcac ttctggtatt tcagatgtcc atgttgaaaa
     9841 atcgtcaaag atcttttgac cactgtaaaa ttcagaagct tcttgataag cttcttgttc
     9901 attcgcgcta agcatcgtag atactagtcc gatttctttc gcaagagtgc ccatcagttc
     9961 ttcattcgaa gcaaacgttg cttctaggaa atctttcgct gaatcttctc cagctactcc
    10021 tttgatcaca taccagccag cgccgccaag gttagaagct tgcgcttttt gcagattttc
    10081 tggaagtgca ggtattggtg caatcttcca ttttccagat tggttttctg ctccttggat
    10141 cgttgaagaa taccaagcgc cagttgggct agaagctact gctcctgatt gtatcgcagt
    10201 tactccagca ttccagtcag aggtttgttc gactagatct tctttcaaaa gagtggcaaa
    10261 caattcaaga ccatacttta aagatgcatt gtcttggatc gtgactgtct ccccatcttc
    10321 agatgtatac cattctcctg cctgttgcat aatcatcctt actcgaccaa ggtcagaagg
    10381 attgacttca gcgattttct ttcccgtctt ttctttgaca tctcgcgcta cttgaatata
    10441 ctcgtcccac ttcagattct ccatatcctc ttctgtataa cctgcttctg ccatcagatc
    10501 cgtacgatag aagtttgctg ttacgcccga atcgaaagga acaccgtata ttttatctcc
    10561 tactttgttt accgcaaatt tatacggtgc aaaatgatct tcctttacaa tagcagacaa
    10621 attagcgaat gcatctggat aagaagtcaa atagccttgt atcctataat cttcaatcaa
    10681 gacgatattg ggcaatcctt ctgtattccc gctcgctaaa gcggtgttca gtttctgaac
    10741 gatatcatcc tgagacatcg taacaacttc tatctctgtt tcttcgttct cataaacttt
    10801 ttttgcttca ttcactgctt tgatattgaa tgtctcatcc cacgcccaga cagtgacttt
    10861 ttcttctttg tctgctgtac tactagcact tccgcatcct gttaagaaac ctgatgctgc
    10921 cgctaaacaa acgactccag caattaactt tctgatgttc atttttatcc gctccttttc
    10981 catccattag ttgtttacgt ttgctacatt catcatacca aaatttgaaa acggtttctt
    11041 tattattcag atacttcaaa aatttctcct aaaataataa aaaaatacaa atcaactatg
    11101 acaaaaggaa taatcttagc atctagacca aagatcgaaa tggtgaggtt tctttaaaat
    11161 aaaaatatcc ttgcattttc tcctagaaat aagtattttt aaattacaag actattctta
    11221 aggcgggtaa aaaaatgcca atacgcgtaa ttcttatcga tgatgaacag acgattttag
    11281 atggaatgaa acagttgatc aattggtctg agcacgggtt tcaattaata gggacttttt
    11341 ccagtccgct gaaagcgctt gatttttctt tggtacatgc aatcgatatc gtggtcacag
    11401 atgtaatgat gcctgaatta aatggaatcg aattatcgcg gctattaaaa cagcaacaac
    11461 ctgaaacaca gatccttatc ctctctagct atgatgaatt tgatatggtt aaagattctt
    11521 ttaaagaagg cgtcgctgat tatcttttaa agcctcgatt gagtcctgat ttttttctaa
    11581 attccttaac tgccgtttca caaaaaatca aaaaaaagcc caacaaaagc ccaatcacca
    11641 atcgttatga gcagatctgc gagaatcttt cacagcagat tgctggacaa actcgtccat
    11701 tgcttgaccc tcttcttttt gaacacacct tgtttttctg ttatataccg aaaaacggcc
    11761 attcagttca aaacaaggct ctaaacaaaa acagtcgatc acccattcat tgatggatag
    11821 cgacgattcg tttactattt atcctgtttc taccttttcg gaagaatccg gctatgtaat
    11881 caatactgat tccaaagata cacttaggaa gtttgttcaa aagtttcgtc aagaagtttt
    11941 tccaggtgat ttttttgttg tttctgattc ttttgcaatc caagatatca atgaaatatt
    12001 ccaagagatc agaaattgca ccaaaggaca acgtttctat cataagggaa agaaccttgc
    12061 ttatcagcat gaacttcttc cgttattaac caaccacgag cagcaagcaa gtagttattt
    12121 aacaaaaatc gttcataaag actacgcttt agctgtcaaa gaacttgaga atttcttcac
    12181 gacgatattg gaacagccta ttgatccagc ttatttgaaa catgaggcaa tcaatcgttt
    12241 ctatgcatta ctcaacgctt tggctgacga gcatgttggg aatgaagaac tttctttgct
    12301 caagatcgcc cttccttctt tattagccga tgctgagtat ttcgaagatt tttctattct
    12361 tgtcaaagaa acacttgaga aactcaccca cttttctgca aatgcaaaaa aagacaattt
    12421 cgatatcttg actttgatct acgagttcgt ccaggaaaat tatgagaaag aaatcaattt
    12481 acaactttta tccgaaaaat atcatttttc atatagctat ctctcagcca tctttactga
    12541 aaaatttggt atcaactttt caaaatatct aaaaaaagtc cgtatcagta aagccaagct
    12601 ctttttgacg gaaacacggc ttactttgac ggaaatctgt gagaaagtcg gctataccga
    12661 actgggttat ttctccagag tttttaaaga agagacagga atgacacctt ctcaataccg
    12721 taaaggaact tttgtaaaat gagaaaaaaa atcaaagagc atgaactctt tgccaaactt
    12781 ctgttcattt tgttcatcgg tctttttctg caagccatcg tcatttcttt gtttatttat
    12841 catcgatcaa gggatgccta tatccagctg ttcaatcaat cgaatgatgt ggtactaaaa
    12901 aagattcaat ctgaatttga aagtttgaat gatacaatcg agaatacatt agccgctttt
    12961 gattctaatc cagctgtcaa aagctatttt tccaatgatc cagcccaaca tatggaacag
    13021 cttcagcaac taagaacaat ccaaaaaatg aatgactctc tttcaaaaat ccatccaatg
    13081 atcgattacg atgtattgat ctttggagaa aatggaagaa cttttgtcgg aaacgacatg
    13141 ctcactgccg tatctgccga ttcttttttt caatctgcga ttgctcagag agtgaatgaa
    13201 cgtgctgctg atacacaaat gctttttgca caccacggat tgactcttcg cgataagaaa
    13261 gcacccagcg tcttctttgt caaaaaactg aaaaatacat tgaatcacgt ttacggatat
    13321 gctgttttat cgatctcatc caagcaacta gcgaatcttt ttcaatctgt agtaaatcct
    13381 gagatatcga agatctcctt catgaacgaa gaacagacga tcatcgcatc aaatgaagaa
    13441 aatacaattg ggagccgatc aatgattttc aaaaaactaa cagtaggtga aacaacgatt
    13501 tcaaatggac agcagttgac ccgtcttcct ctgtaccgcc aggattgtac attactcagt
    13561 caagtcgatc ttcattcttt atctaaccaa atgggcgtga tttttccgat tattttgtat
    13621 aatatcgtga cacttgcttt tgctggctca ttggtattta tgtatttgga tcgacacaca
    13681 aaatcgatct accgcttgat tgattcgcta aaacggctag aggaagatgg cttaaaagct
    13741 actgttcctg tacaaggaag ccatgaagtc caattgctag ggaatacgat caatcaattg
    13801 ctaagtaatg ctcagcatca ttatgaacag acgatccaag acgaaaagaa gaaacgttcg
    13861 cttgaaatcc aaactatgca agcacagata cagccccatt ttatttataa tacgctgact
    13921 agcttgaaat ttttgatttg gcagaaaaaa acagatgaag cagttcaagg aatcgacagt
    13981 ttcattactt tactaagaag tacgattggg aaaaaagaag aagtgattcc agtcaaggaa
    14041 gaaatcaaaa gcgtacaaag ttacatcgat cttttgagta tgcgatatgg cgaaagaatc
    14101 tcggctaaaa taatgattcc tgatgaactg cagtcattat ctatgccgaa tatgatcctt
    14161 caaccaatta tcgaaaacgc ctatcttcat gcttttcaca ataaaacgca aggattcatc
    14221 acggtgtacg gcaaaacaaa aaatcagctt cttttattcg aagtgattga taacggcgat
    14281 ggcttcgata ctgaaaatac caaacaaaaa aatgatcatt tttcaggaat cggcatcagc
    14341 catgtagatg agcggatacg cctaatgtat ggcgatgcat atggcttaac gatccaatca
    14401 gtgattggga caggaacgac tgtaacgatt tgtctaccgc ttcttcctaa aaatcaatca
    14461 gaatatcaaa aataaagaat agccaagcgc tgattttttt attttaagtt aaataaatca
    14521 atcagtattc ttgactttca tctacgcgtc tcttctactg tcagcactgg ataacagccc
    14581 aatatttgac tttctcctcc gagcatcttg atttcttgga gcgcattctc tactaatgtc
    14641 attggacggt ccaacaacaa atcgatcacg aaaaaatatt ctcccaagct agttttcaat
    14701 ggtcgggatt caatcttact taagttgatt tcccgccagc caaaagctgc cagcatttta
    14761 tgaagcatcc ctggccgatt agcaggtagt gtcaagatga cactcatttt tactggagct
    14821 gactgctggc tggtcatctt tcggtcaccg acgatccaaa aacgtgtctg gttcaactca
    14881 ttatcttgga tattctcagc taagatctcc aatccaacat gctgtgctgt ttctaatgaa
    14941 gcaatcgctg ctgcgtcttc tttcggatgt tctgctacat acattgctgc agcagttgtt
    15001 gattctgttg ctactaaagg aacattagga taatgcgttt ctaaaaactg ttgtgattgt
    15061 gctagtgctt gtggatgtga aaggattttt gtaatctttg ttgctggatt gcctaaaagc
    15121 tgctgcttga taggaagaac gatttcactt ttaacttcga cttctggatg tttggaaaga
    15181 agatcgattg tgtgatgaac agctccttcc aatgaattct ctacaggaac gacagccaga
    15241 tcgacttgtt tgcgaaacaa agcgcgcaaa caaacaggga tggaagcata cgcagtcaat
    15301 tgttctgtag gaaatagctg acaagccgcc tgataagtga atgaactttc tggccctaga
    15361 tagctgacgt tcatatgctt ttgatccttt ctataatggt atcgatgatc ttttctggtg
    15421 tttgattggt cgtgttgatt cgatgtgtcg cactttcttc ataccaagaa agtcgttgtg
    15481 ccaataatgc ttttatttct tctcttgttt ttccaagagc taaaggtcga atagacgttt
    15541 catcttgttg gatacgatca actagacagt ccgcttctgc ctctaagtaa agaacaatcg
    15601 gctgtgtttt taaaaaacgc cgattttctg cactttggac aatccctcca ccagtcgcga
    15661 taattttgtc ttcatttgac agctttctta aaatatctga ctccactttt cgaaagcttt
    15721 tttcaccgta atagtgaaaa tattcggcaa tcgacaattg gatatgttcc tcaatctttg
    15781 tatctaaatc tacatactct ttttgtaaac attgagctaa ccctttaccg attgttgttt
    15841 ttccagcgcc catgaaacca atcagcaaaa tgctagccat gagcttctcc tcctgacaca
    15901 agttctgcta aatcgtcaaa aaatgccgga taagagattg aaacagcttc agctccttct
    15961 agttcgcaag gtccatcagc tatcaaagca gctacttgca gcatcatacc gattcgatga
    16021 tcgcctctgc tggacacttt tgcgccatgc agaggtgtcg gcccatggat gatcagaccg
    16081 tctgctgtcg cttttatctt tgctcccatt ttctgtaatt cttctgccac cgcatcaatt
    16141 ctgttggttt cttttacttt taattcttct gcgtctttga tgatcgtgat tccttctgct
    16201 tgagtagcca ctaaagctag aatgggcaat tcatcaatca gacgcggaat gatttctcca
    16261 ccaatcgttg ctttcttcaa atgactcgtc ttgacactta aatcagccga ttggttctgt
    16321 tcattgtgat tcgtctgggt aatcgctgcg cccatctcct ccaacacatc taagatacca
    16381 gttcttgttg gattgacccc gacatttttt aacaacagtt ggctttccgg aacaagaagt
    16441 cctgctgcta gaaagaaagc agctgatgaa atatcacctg gaacagttat ctgttgacca
    16501 gttaattttt gcggtccggt cactatgatc gttttatctt ccactgtgat ccttccgcca
    16561 aattgacgaa tcatttcttc cgtatggtta cgggaacgtt ctttttcaac gattacggat
    16621 gtgccttctg cttgtaatgc cgcaaacagc aaagcagatt tgacttgcgc actggctaca
    16681 ggcatattgt atcggatagg tgataaagag cgggttcctg tcacagtgat tggtagatac
    16741 tggtcatttt cttctccttg caagtcagcg cccatctcgc gtaaaggttc catcactcgc
    16801 cccattggac gtttagacaa cgaagcatcc ccgaacagag tagtcgtaaa aggctgtcca
    16861 gccaaaatac ccatcaataa acgtatggtc gtaccggagt ttcccatgtc aattgattcg
    16921 gttggttgga caaatgagtg gctaccgcga ccatgaatct tgatcacctc ttcctcttct
    16981 tcgatctcga cacctaattg ttggaaggca tgtaaagtac tcagacaatc ttctgcgcgc
    17041 aaaaaatttt gtatagtcgt cgttccttca gcaattgctc caaacatgat gctgcgatgg
    17101 gaaattgatt tatctgctgg tatcctaaca gtccctctta atccatgtat ttgttgtaat
    17161 aattgcattt atccagcctc ctatttgatc cagcaatgat aactggtatt agacataatg
    17221 attctttttg cttgtaacaa atcctgttgg tttttaaaac tgatttgcag tattcctaaa
    17281 atatcttccc tggtctcttg gatcttcaaa ttaatcaaag aaactcccgc ttttccgatc
    17341 agtccagtta cttctgcaat aacgccaggt tcatctggca catcgataaa taaatcaaaa
    17401 aaggcaggaa tcgcgccttg cttatggaca ggcaactggt ctcgactttc ttttgcccga
    17461 ttgaaaaaag aaaagatttc cgattggttc tcagtcatga tccattctgc tatttgtgtc
    17521 atttcttgtt gccaatctgc caatcgttcc aataatatct gcttattgct caacaaaata
    17581 tctgtccaca tgacaggatc tgaggaagcg atcctagtga tatctcgaaa gcctcctgct
    17641 gccagttgtt tggctcgcgg atactcttga ttgaattgtt ctgcctgatt gactaagcca
    17701 gctgccagaa tatgtggaaa atgacttagc attcctgtta tacggtcatg ttctcttgct
    17761 gtaagagtta catattttgc tttggttccg caaaatagtt cttgcagttt ttcaacatct
    17821 tttttcgtct tttccaaagg tgtaaagatg taataggcat tttcaaatag tttagcatct
    17881 gctgcctgta tacctgattt atgagaacca gccattggat gtccaccgac aaaccgaaga
    17941 tttttctgct cagcggatgt cacgacttgc tgcttcgtac tgctgacatc cgtaatgatg
    18001 acgtgatcag acaagttgat tctttcaagg acatcaagat aagctaaggt tgtacggacg
    18061 ggaacggcta ataagataac gtctgcttgt tctgcacctg tttcaaaatc acttgcaacg
    18121 taatcaacga tctgctgttc tactgcttgc tcacgggttt ttgactgact atcccaacca
    18181 actactatca gttctggatt ggtctgacga atacaaagtg ccatagaagc accaatcagt
    18241 ccaagcccca cgataaaaac atgttgtgcc atcttatttg cccccttttt agtaatgttt
    18301 caagtagtca cggtactcct tcactgcagc tttcaactca acaagcgaat cacttgggaa
    18361 ttttgacaat agctctgtcg ctaccacagt ggctacaaca ttttccgcaa cgacgctagc
    18421 tgcaggaact gctgtactat ccgaacgttc tacacttgct ttgtaaggtt cttttgtatc
    18481 gatatcaaca ctttgaagtg gcttgtacaa tgtaggaatg ggtttcatga ccccgcgaat
    18541 gacaagtggt tcgccattgg tcattccgcc ttcgaagccg cctagattat tggtacgtcg
    18601 gaaatagcct ctttcttctt cccataggat ctcatccatc acttctgagc ctggtaatga
    18661 accagaagtg aatccgaccc caaattctac gcctttaaag gcattgatac taaccacagc
    18721 ttgtgcgatt ttggcatcta gcttcgtgtc ccattgtacg tagcttccta atccagctgg
    18781 aacgcctcca acgagcactt ctacaattcc tccgatcgta tctccatttt tctttgtctg
    18841 atcgatcaaa tcttttattc tttgctcaac tgctggatca acaactcgta cttctgacgc
    18901 ttcagaaatt tctttgattt cttgaatcga gatatttcca ggtatttctg cttggattcc
    18961 accaagacaa atcacgtgtc ctgctacgat gatgtcaagt tcttccagaa ttttcttggc
    19021 aattgcgccg attgctacac gcatggtcgt ctctcttgca gaggaccgtt caagcacatt
    19081 ccgaagatct cgatgatggt atttcatacc gcctaccaaa tccgcgtgtc ctggacgcgg
    19141 acgtgcaact cgccgcagtg attggtcttt ttcaggcact tctgctacag acatgacagt
    19201 tgtccaattt ttccaatctt tattttctac cactaaagtg acaggtgaac caattgtttt
    19261 gccgtgacgg atgccagacg tgatccgaac acgatctttt tcgatcttca tccttcctcc
    19321 tctgccgtaa ccagcttgtc tgcgagcgag ttcgtgattg atttcttctt ctgacagagg
    19381 taatcctgct ggtagtcctt caataatggc tgttaattct ggtccatggg attctcccgc
    19441 agtcatataa cgcatcttac agtcctccta agtaatcttt gaatgtctct gtgggaacag
    19501 gaacgatttt tgcttgccca atcttttcta gcaagatgat attcaattgg cttcctcttg
    19561 ctttcttatc atgggttatc gcgtggaata attcatctgg atgacttaga tcgtacgtaa
    19621 tcggcagatg gaatttttga agtatccttt ctaaagcagc tgtcgatcca gttggagaca
    19681 agccgatttt ttctgcatga gaagtgatgg ctaccattcc aatagctact ccttctccat
    19741 gactgactac cccatatcct gctgtatttt caattgcatg gccaattgta tgaccaaaat
    19801 ttaaaataag tcgatttcct tggtcaaaga catcttcttc cactactttt cgtttgattt
    19861 ccaacgtagc agtaatgatt ggaacagcat gttccagaag atctttttcg tctttcagct
    19921 cgttcagctg tttccaaagc gttgcatctg ctatagctgc tgatttgatg atttcagcga
    19981 ttccttctcg taaacgacgt accggcaaag tttttagaac ctcaggatca atcaatacac
    20041 cagctggctg gctaaatgtt ccgacaaggt ttttcgcttt gtttgtattg actgctgtct
    20101 tcccgccaat actagaatct acttgtgcaa gtagcgtagt cggaatttga acgaaatgga
    20161 tcccacgcat gaacgtcgag gccacgaatg ctgctagatc acccaccatt cctccaccaa
    20221 gtgcaagtat cccatcgctg cgggtaaaat cattatctgc taaaaaatcg tataactcag
    20281 ctgcttgttc taaagattta ctggtctcac ccgccggtac gattgaaagg actggttcaa
    20341 aattagcttg tctcaattgg aacatgattt tttctgcata tagtggagca acgtttgtat
    20401 cagtgatcac agctactttt tgaggtctcc aaatcgtttg aagccatgat ccagcctgtt
    20461 ctagtgcgcc tttttcaata tgaatatcgt atttttggtt atcaacatgt acagtaagca
    20521 ttcgtttcac ttctttcttt taaaaagctg gaattaatcg agtgtctgaa tcttttccat
    20581 tgcttctttc atgatcgcaa cttctttcat catgcgtgag taagtctttt cattcaacga
    20641 ttggggaccg tctgaccaag catttgcagg atcaggatgg atctctacga tcatgccatc
    20701 tgctccgctt gccacacccg cacgagccat tggtggtaca agttcccaaa ttcctgtacc
    20761 atgacttgga tcaacaatca cagggaaatg agttaatttt ttcatcaatg ggacagcact
    20821 taaatcaaac gtattacgtg tcgctgtttc gtaagtccga atcccacgtt cgataaaaat
    20881 gacaggagat ttgtcttcga ctgcaatgta ttctgcagca ttaagccatt cattgatcgt
    20941 accggaaatt ccacgtttca atccaacagg tttacctgtt ttaccgacag cagatagcag
    21001 tttaaaattt tgcatattac gtgcgccaat ctgtaggata tcgctgtact cagccaccat
    21061 atcgatatgc ccttcatcca tcacttcagt aatcactttc attccaaatt catcagccgc
    21121 ttgacggatg tatttcaatc cttcttcttc taaaccttgg aaagcatatg gagaagtacg
    21181 tggtttgaag gcaccacctc gcagaatttt tgcgcccccg gctttggcca ttcgcgcaca
    21241 ttctctgatt tggtctaatc cttcgataga acaaggacca gccatcgtca cgaaactgcc
    21301 gtcaccaatt tttactccgt ctacatccac gactgtattg ccaggatgga attctcgaga
    21361 agtcaatttg tatgtgttta aaatacgcac agcattttct actccttcat agcgtgtaaa
    21421 tgctccttct tgtaaacttc gcgtatcacc ttttagtcca atcactactc gttctgttcc
    21481 ttgatcgatt gagactttga atccttcttt ttcgatatga tcgacgactt tttttatttg
    21541 ttcttccgtt gcttcttttt tcataattac tatcattgtt tttcccgctt tcttttgttt
    21601 acttatctat cttggctgat tttctctact ttttcaaggt ggttttacat taattcctac
    21661 taaatgaccg tgtcctgttg ttctcatttt cgctccttct ttcctactta tgacccagat
    21721 aatcaacaaa aaaagatgtc cctgtaggaa attgcctcta cagtgaacat cttcaacgag
    21781 ccttaaaaag cgctgcaaaa atataaaata gccactatag atgaatttct ctacgtggct
    21841 gtaagtcgtg tttaaaaatc tttagccatc atagatacaa acctggtttg tttgtaccca
    21901 cgaagtcatg aatacaaacc tatctaaaat agctaaagta atacgtattc agttttgtaa
    21961 gttttctaga tttcataaaa aatcgctcca aactgatgta agaattgtac ctagtataga
    22021 cataaaaaaa tcgactgtca atcattttta tgaaactttt tttaattttc tgatagttaa
    22081 ctttgttttt cagaaaaata acaattggtt ttattgaaga aaatagtcat gaacaaaagt
    22141 atctgagaac ttttttactc tcttgttcat gacatataga ataaagcagc tttgtcttgt
    22201 aaactccgtt tttcaaataa taatctaaag attgctactg aataataaag ccgatttcat
    22261 ggtcctcttc gctgctgatt cggtaaggtg actcaacatc cgctccccag ctattgatac
    22321 ccccgactcc tcttactttt gcaaaaatcg taagaaccgt tcgtctttct ggcggtagtt
    22381 cttctatatg tgttgcctgt tccagttctt ctgctttgaa tggtaaagcg gaaaaagcaa
    22441 atggcgtatc ctgctgttca aatcgcaacg aaaaatcttc ttgatcttta tccgtattat
    22501 ccaacgtttg atttcttgtt agttctaccc atttcgtttc catatgcatg ccgcattctt
    22561 ggggaacaag gtatggggaa acggggagtc ctgccacttt ataaatacct tcgacaccac
    22621 cagccatccg atccggatat gtttcccctg ataggccttc atactcaaaa aattttgctt
    22681 tcgttggcat aatgaacctt aaacccaatg cgggtaattc cggtaatcct ttttgtccat
    22741 aataatgcat attgacaagc attttaccct ctccagcgat ttggtaggaa attgtcactt
    22801 gggtttttgg tactgtgttg atttccagtg taaaaatgat ttcaaccgtt tcagcgtatt
    22861 cattacttga atattgatta tttactggag caatcggcaa atcgatcttt ttattgtcca
    22921 ccagtacttc tatttctttg acttttggat acaatccggc tcctaaccac ataccggatt
    22981 taaatccaaa tccgctacct ctgtcattat cggtcgttgc tcgccaaaaa actggaagtg
    23041 tttcccggta tagccattct tttccgtttt tattgagcga ttccagtccg cctcttgtat
    23101 aagaaaaaat ataatgcgta ttccccgatt tgacacctaa tgtacagtcg ccgaagacga
    23161 ttgcaacttt ttccgtatcc atatgacttt tatttactgt atttttcata ataatatctt
    23221 acctcctgca tggcgggttt ttcttgtcca tctgcaaaaa cgatcccatt ccctgagaat
    23281 tcatagtcac ttggtttatc gtcaaagtca ccgccatagc gcatcacttc tctgcctgtg
    23341 attggatcag tcacttggat cgcctgatct ttaaaatccc atatatagcc tccttggtac
    23401 atttcataac gatcaagcaa cgtcatgtaa gaatccattc cacctaacga attccccatg
    23461 tcatgcatat attcacataa gatgaacggt ttttccgctt tattttcaag gtagtcaatg
    23521 atctcttctg gtggcgcata catgcagctt tttacatctg aaatcgaatc ttcgaatgct
    23581 ggatttggaa aattcccttc ataatggaca agtcgatcgg ggtctacttt tttgaagtaa
    23641 tcgttcattt gtcgaatgtt ttcttccgca taagattcat ttccaagaga ccaaaaaaga
    23701 atacttggat ggttttttaa tgtttcgaaa ttcgtttttg ctcgatcaag aacagccgcc
    23761 tgccactgag gtactgcacc tggtacgttg taagaaggct caaatgcgcc cattttttgc
    23821 catgagccat gggattcgag gttcgtttcc gccatcacat ggattcctgc ttggtcgcat
    23881 aaataatacc aagtgatctg gttggggtaa tgagatgtcc gtacgccgtt gatctttgca
    23941 ttttttatga tagccaaatc tttttccata tcttctatag tgatggcgcg tccttttttc
    24001 ggatgccact catgtcgatt taccccgttg ataatcatcc gttttccatt gaagtagatg
    24061 attttatctt tgatttcgat tttacgaaaa ccgaaggaat agtcaatata ctccgttact
    24121 cttttttctt cgtctatcgt ctccaattca agcttatata aattgggctg aaaatgcccc
    24181 cacagtgcca cattttcaaa tccatcgatg cgaatcgtca tttgctcttt taacggatat
    24241 tgctgttgat agatttcctt cccatcagga tctagtatcg ctacattcag ctgactgttt
    24301 ttggctactt gctcaaaaga caaatctact tcaagtttgc cattttgaca tttgtcatct
    24361 aagcgaggtt tgatccaaag atcttctaaa tggttttgtc ctcgagcaac taagaagaca
    24421 tctctgaaga tcccaaaaaa tcggaaaaag tcctgatctt ccaagaatgc agctgtactt
    24481 cttttgtaaa cctccacagc tagaatattt tcttcttcca aataaggtgt taaatcaaat
    24541 tcagacggag tgaacgaatc ttcggcatac ccgataaaat gaccattcaa ccaaataaac
    24601 attgcttgtt ctacaccagc aaaatgaatc gagatttgtt ttccctttag accttcttct
    24661 aatcgaaaag tcgtcaaata cgaaccaacc ggattgtctt tagcagctga aaagatccct
    24721 tccgcctctt tctcagggct tgtcgtgaaa gggggacggc gaaatacatg tccctcccac
    24781 ggatacatcg tattgatgta atggatcttg tcataatttg ctaattcaat atgactagga
    24841 acagtgattt catcaaaaga acaggcatca aaatcttttt tataaaatgt ttttggtcgt
    24901 accgaaggat ttggcgaata acaaaaacgc catgatccat ttaaagactg tttaagggag
    24961 gatgtggttt ctacttcttc ccttgttgca taacaaacat gatcgctatg tgcatttgat
    25021 tggttcactc taaaaacttg tggatcatct aaccatttta tatttgcttt catacttttt
    25081 tccttctctc tcataacttt ttgaaatgaa gcagttctgt ttggaaatca ccttgaaaat
    25141 cggggaagta aagtccaact gtcatcaatt cggcccccga aaatatccgc ttcgaggtct
    25201 gttcctgata aagtgcctca tcatctaacc ccatcagata tacttcatgg aacgctggtt
    25261 gagctgaagc tagtatcctc cctaaaaaca caatagcttc atcttgttta ggagacacaa
    25321 acatccatgc ggcaatattt tcttcaaaag gactcgccaa acgataataa tggccatact
    25381 ggatcaccgg acgaatcgtt tgataggata taatttggtc ttttacttgc tttttttctt
    25441 caggagacag ctttgtcaaa tccagttcat aaccaaaaac agcgctcata gctgtttctc
    25501 ctcttgtttt caacgaagta gatctgtcgg tctgatgatt tggtacagct gatacatgag
    25561 ctgtgatgga cgaaatcgga taagcaaggc ttgttccata ttggattttc atacgctcca
    25621 ctgcatccgt gttatcactt gtccatgact gcggcatata ataaataaac ccggcatcaa
    25681 accgtccacc tccaccagaa cagccttccc ataagatttc cggataatca gttgtcaaat
    25741 gttcaagtag ttcataaagc ccgagcatat aacgatgcgc tacttctcct tgtctctgtg
    25801 ggtcaagggt aatcgaatag acatctgaaa gcgaacggtt catatcccat ttgatgtagt
    25861 caagaggaat cgtatctaaa atctttctca tttgtttctc aatcgtctgc cgaacatcta
    25921 accttgtaaa atccagtaca tgttgtgatc tggaagcaga aggcattcta cctggctcct
    25981 gcataagaaa atcaggatgt gttcgataca gttcagaatc aaccgagatc atttcaggtt
    26041 caaaccataa accaaatttc aatcctttgc tatgagcata atctgctatt tcacgtaatc
    26101 catttgtcaa cttgccttca tactcgaacc agtctcctaa tgaagaattg tccgcatctc
    26161 tttttccaaa ccagccatca tctaatacga acatttcgat gcctagctcc tttgcttcat
    26221 caatgatcgc cttgattttt tcactattga agtcaaagta agtggcttcc cagttattga
    26281 ccagaatcgg ccgttcagca aattgatgac gacctcttgc gattctttca cgtagcaact
    26341 catggtggat ctgactcatt ttgttcaatc cctgacttga gtaagaaagg atcatttcag
    26401 gtgtttgaaa agactggcct gcattcaatt cccacgaaaa acgatggctg ttgatcccac
    26461 cgacgactct caattgattg atctgatctt tttcaagttc gaaagaatgg ttgccggaat
    26521 aaacaaattg aagtccgatc gcttctccag tattttctgt cgtatgatga tgaactaaag
    26581 caataaagtt attcatatgg tgactgctcg ttcctcgacg gctttcaaat acttttgttc
    26641 cagataaaac agattgccgt gaaatctgtc tttcattgac atgtgctcct ggcaaagcaa
    26701 tgacttcatc aaatcgccta gtatgggcaa agtctagctg gaaactagcc gctttttcta
    26761 gtttgattgt ttctccggtt tcatttctta tctttacaga tcgtgtgatc actgctctat
    26821 cagtaaatat ggtatagaac aaatcgaaat aaatcgctgt ttctctatcc ttaagtgaaa
    26881 tcaccaacgt ttgtgcctct gacttgtcca tcacataagt ttgaggcaag ccttcgatct
    26941 ctggcttccc atctgtaata taatggctgt catatctcag atccagtaag tctgatccat
    27001 tcttgcgctg aatgatcgat gcgggcgttc gaaagtccat gctgccatga gaagagtatt
    27061 cttgcggtag tgtatctttc gacagagacc ggtcaggatt taagggaaca tttcctgaaa
    27121 atccacgatc tcttcgggga taatttttat tgtctttgta ctgcttgact ggtttgccaa
    27181 aataaatatg cgccaataca ttgctttctt ctatctttat cagataagaa agaaatgtat
    27241 ttcgtaaatg gaagactcgg ctcttttcat caaataagat gaaattttta tctgtttttc
    27301 tatgcgtaat atccatcatt tcactcccaa caaaacggaa accgtttact tttttttata
    27361 attcctgtat actgtttact aaacaatttt gtcaataaaa attttttatt tttttgagga
    27421 gtgtgtaaaa atggttggaa ttagagatgt cgcacgaaag gcaaatgtct ctcctgctac
    27481 agtttcccgt gtgttgaata acgatcagac gatccatgtg gctcagacta ctcggcaacg
    27541 gatagtagag gcagctgctg cgttggatta tgacatcagt actcgtaaat atatcaaaaa
    27601 gagaatgcct tcgattggtg tgatctctac gatcggcaaa gcgagcgaag aacaggatat
    27661 ctattacaaa catttgcgag tagggatgga agaagaagct cgacgtctgc atttagggat
    27721 gaatcgaatc tataatctat ctgataatcc taaacaatgg gaagatctag atcagttagg
    27781 tgcggtgatc gttgttggga ctgttacgaa agaatcgatt accgccttgt taaaacaaaa
    27841 catgcaaata gtcgtcgtgg ataaccctga catccagcaa gaggtcgata tggtgtatgc
    27901 agatcttgaa cggatgacta aaaccgtact ggaattgttc ttagaaaatg gtcataaaag
    27961 aatagcctat atcgggggat ataaagtcga tatggatgaa ttcggtggga agcagatttc
    28021 tataaatgaa aagaggatgc gtgcctatca gcattttatg atcgatcatc acttagaaaa
    28081 atatatgtct tatcatctag gtggctggac agaaaaacaa ggtgaggtac ttgcgactaa
    28141 tctattagaa aatgaatccc ctcttcctac tgccattctt gtcgggagcg atccaatggc
    28201 aattggtgtc tatcgggcat tgaaacaaaa aaatatccaa attggagaag agattgttgt
    28261 agcaagcttt gataatatcg agacaatcgc aaacctctcc cctggcttga ccagtgttca
    28321 aatcaatgcg aaatcaattg ggcaagcagc tgttcgaatg gcattggagc gaattgacgg
    28381 tatacgggac gaaccaatca ttttgactta tcctgcacga ttgattgtta gggaaagttt
    28441 tatcccaaga acaaaaaggt attgaaagag aggttgtgaa aagccgcttc gtttcttcat
    28501 actcaaaacg aaacggcttt ttcacaacct cttacttata cttattcaca aaatccaatg
    28561 tctgctggta acaattttgc gattctttta gcgtgtaatc aaattggtat tcatgggtaa
    28621 tctctttttt tgtatctgta taaaacaagg attgcacggg tacctttaat tctgtcaacc
    28681 gattttctaa tgcttgacct tgctcctgga atgagtatgc atttccgtca gttatatacg
    28741 ttggcggaaa ttccttagaa acatggtcag ccacactagc ttctttcaat tgctcactcg
    28801 ttttccaatc ttttgttcca atcaacgacc acgcaacggt tttgacgaaa aacttcataa
    28861 atcgatcatc cgaatgctgc tgtgctgtta gcttcaaatc aacaggtccg caataagaaa
    28921 tggttccttt cagactatct tttggaagta gctgtttgat tttcatttgt ttagcatacg
    28981 catcattcgt ttgtatagct gcatattgca atgcgatttg tgaacctgca ctatctccac
    29041 caaaaaataa ttgttccatg tctagcaatt tgtcgtcttt ttcttcagct aataaatctt
    29101 tgatcagttc attcacttga agaacttgat tagggtattc tgaatcaggc gctaattcat
    29161 aattcatcgc aaccactgcg atgttggcgt ctgaaactaa ttttgtcgca aattctttga
    29221 cacccgattt atctccgccg acgaatcctc caccatgtac ccaaaataga acaggaacag
    29281 gccccttgct gttttttgga tagtagatgt cataagtatt ctctttatac ttggactcat
    29341 acgtcaaatc tgtttttttc gccacgtttt tttctgcttg atcgaacgtt tttttatcag
    29401 tgatttgaac agtatttgaa aacatatggt tgatcaagaa tgctccaggt ctgggggaaa
    29461 gctggaaggc aagaaagatt gcaaacgcga tcccaagaat gattccgaag aaccatccga
    29521 taaatttaag aattttcttt ttcataaggc tccctcagta gttagtatta agcattctga
    29581 ttataccata gtgttatttc ctatcaagct ctcctagatg atttaatgat tttccccaaa
    29641 cttcttctgc aatgcttttg acaaaagaaa ttttttccat tgttcttcaa acaaaacatt
    29701 ttcttcttct gttgaagcaa atccacattg aggacttaag cacaaacgat ccaaaggcag
    29761 atatcgtgtc gcttcgtaga tccggtcaat cacttgctgg tgctcttcca tttcgccatt
    29821 tttcgttaca gtcaaaatct aagacaacta atttatcttc agagactttc tctaaaagaa
    29881 caaaactccc agcacgttca ctatcgtatt ctaaataata ggcacggaca ttttcttgag
    29941 taaaataatg ggtctgctac gtcgtcatcc cccctgatgc cgccaaaatc gaataataat
    30001 ttccgcgtca aacatgtata tttagtgttg aatcatttga gaatatgaaa ataaaaatct
    30061 ttttgatcaa tcagttaatc aaattgaaat aacgaaaaat ctgagacaga atgacgttca
    30121 ttctgaccca gatttgattt tgcacaactc aacagtcctt attggcaaat cgccaaaata
    30181 atgtagacta actaaaaaga ctaagaaaca ataacaaaag ttaacacttc ttagtctttc
    30241 tttagcacgt ctatttatta aagattttag ggccttttct catgttttta cgatcattct
    30301 taggtgtttc catttgtttg gatcggcctc caccttgttt ctttttgatc aattctttca
    30361 ttttttcttt ttggtccatt tttattctcc tttaacgaat gaagcgacta attcgatatg
    30421 atgggtttgc gggaaaagat ctacaggctg aactttcttc acggcataac ctgcttctgc
    30481 aaataactta gcatctcttg caaaagttgc cggattacat gagatataga cgattcgttc
    30541 tggtgacatt tcgattgctg attcaataaa atgatgatct aatccttttc gtggagggtc
    30601 aactacgatc acagatggtt tgatcccttt ttcttgccat tttttcataa ctttttctgc
    30661 ttttccgact tcataatgaa cattttcgat tttattattt aaagcattga actgtgcatc
    30721 ttcaattgct tctggaataa cttccatccc atacacctta tccactctgt ctgctaaaga
    30781 caagccaatc gtacctattc ctgaataagc gtcgatcaca atgtcttttt tatctaactc
    30841 ggcaaactcg atggctgttt ggtacagata ctctgcttgt tgagtattta cttgataaaa
    30901 tgactttgct gagattcgat aggtttttcc taatagctga tcttcgatat agtctctgcc
    30961 atataaaact ttttctttgt ctcctaaaat cacatttgtt ttttcttcat tgatattttg
    31021 gatgaccgaa accacttctg gcaattcttc atgaatagct tcagcaattt ccttggattt
    31081 aaagaatttt tctttacgag taactaaaac gaccatcatt tcatgggaat aatgaccacg
    31141 acggataatg atgtgacgaa gctgtccttc atttttttct tcattatatc ctcgtacttg
    31201 gaaccgttgc aagatatctc tgactacttt gattgcttga tcgatgacag gatcttggat
    31261 ataaaaatct tcgataggga ctagatcatg gctattcttt ttgtaaaaac cggtggctaa
    31321 ctgtccatcg atacggcgaa cagggatctg tgctttatta cggtagccga atggttctgc
    31381 cattccgacc gttggaagta caggaacttc tggcatctta gcaatcttcg ccattacatg
    31441 ctctacttgt ttttgtttga agacaagctg ttgttcatac ttcaaatggg ctaaaggtgc
    31501 gatacctatg cgaagtaatg cattgttttc tacaggctga cgatcaggtg attgtgtaat
    31561 aaatgtttcg acttttccat atccaaactt attgcctgct tttactacta gtatttctac
    31621 ttcttctcca gggagtgcat tttcgataaa taatggataa ccatcgattt ttgctacccc
    31681 cattccttca taactcaagt cgacgatttc gactgtatat cgttcgtttt tctttactat
    31741 ttgctgttct gtcatatttt gctcctttaa gcctattttt caatcctact gaactctact
    31801 ataaatcagc taattacaca actaaaaccg gcactgacct tactacgttc agcaccggct
    31861 tttgattaat tcttttgatt aggtgtttcg tctgctattt ttccgtcacc gtcgatatct
    31921 tcatccgtta aacgttcgac ttcttttacg aattctttgc tgacaacctc taattcttct
    31981 tcatctgtac ctgtgattgc ttcatcagga atctgatcgg tattggcaaa gaactcaatg
    32041 tgttgatgaa gattttggaa atgcatcggt gcttccccgc cgtattcacc atctaagttg
    32101 atcattactg gtcgattgat atcatcttct gtttcaacga acaaactgct tgttttggta
    32161 tagattattc ttggatcatc gacatgtcga ccgccattca gcatgagtgc tgcaatatgc
    32221 aagatctcaa agatatttgc tgtcttcaca atgattaaag aaaacttccc atcatccaat
    32281 ttggcatctg gcgcgatctg ttcgaatcct ccaacagagt tcgtcagccc taggaaaaac
    32341 atcgaagcat ttccgatata ttccccttca tcatacttca agcgcatttt gattggcttt
    32401 actcgaggga gcatctctgc tcctttcgca agataagcaa gataaccaaa aatactcttt
    32461 agttctgatg gaacttcata agtcaattct gtcaaatagc cacctgcagc gatattgatg
    32521 aagtaactgt tatcagaaag gccgatgtcc atttttacgg tttggtgttt ttttatcact
    32581 tctgctgctg ctttaatatt atctctagga atttttaatg ctcgagcata gtcgttcgtt
    32641 gtaccagctg ggatgatggc cattttagga cggtgttcaa gcggagcgat tccattaacc
    32701 acttcgttga ttgtgccatc gccaccagct gccactacta gatcaaaacc tagttctgcg
    32761 actctacatg cttcattctt ggctgaatct ggttctggtg tagttgcata ggcgctggct
    32821 tcaaatcctg cttcttctaa tgcctgtagg atatccgcca aatttttttt caataattct
    32881 tttcccgagg tggggttata aattacgcgt gcttttttca ttttcagcct ctatcgtttc
    32941 gctaattcat ctttaagtag cttattcacg acaccaggat ttgcttgtcc tttagttgct
    33001 ttcatgattt gaccgactag gaagccaacc gcacgatctt ttccattttt gaaatcatcg
    33061 acagattgtt ggttgttatc caaaatttca ttaatgattg gcagtagttt gttcggatca
    33121 gataattgca cccaaccatt tttttcaact acttcttggg cttctccgcc atttgtgatc
    33181 aattcacgga agactttttt ggcgattttt gagctgatcg ttccatcggc gatcaaacga
    33241 atcattcctg ctaagttctc aggtgtcaat tttgtctcag ctaattccag tttctcactg
    33301 ttcaagtaag cagaaacttc acccatcaac cagttagatg cttgcttggc atctgcacca
    33361 ttttccaaaa cagcttcaaa aaaatcagac atttcttttg taagtgtcaa taccattgcg
    33421 tcatactctg gaagtccaaa ctcacggata tagcgttcgc gacgagaagc tggcatctca
    33481 ggcaaactag cttttacttt ttgaatccat tcgtcatcga tcacgaattt cgggatatca
    33541 ggctctggga agtaacgata atcactagac ccttctttga cacgcatcaa aactgtttta
    33601 ttcgttgttt cgtcaaaacg gcgtgtttct tgttggattt ctcctcctga aagaagaact
    33661 tttgcttgac gtttttcttc aaaagctaaa ccttttttca cgaaagataa agagttcaag
    33721 tttttcaatt ctgctttcgt accgaactct tcttgtccat aagggcgaag agaaatattg
    33781 gcatcacagc gcatagagcc ttcttccatt ttcacatcgc tgacttctgt aaattggata
    33841 attgatcgca atgcttctag ataagcgtat gcttcttctg gtgaacgcat atcagcttca
    33901 gaaacgattt cgatcaaagg cgtgccttgt cggttcaaat caacgtaaga ataaccgcca
    33961 ataccatgca tgttttttcc agcatcttct tctaaatgga cacgttcgat ccggattttt
    34021 ttctttttac cttctacttc gatttcgatc catccgtcat gaccgattgg ttgatcaaat
    34081 tgggaaattt gatatgcttt tggattatct gggtaaaagt aatttttccg gtcaaaatga
    34141 gtatctttag agatttcaca gtttaatgcc aaagctgctt tcatcccgaa ttccagcgca
    34201 gctttattca ttactggcag cacgcctgga taaccccagt cgatcacgtt tgtattgctg
    34261 tttggttctg caccaaaatg agctggcgct ggagagaaaa tttttgagtt ggtttttaac
    34321 tcgacgtgga cttctagtcc aatgactgtt tcaaaattca ttcgtctttc cctcctaaaa
    34381 tagctggttg ttgtttatgg aattctgttg cttgttcaaa cgcatatgcc gcttgataca
    34441 tcgttttttc atcaaaataa ttaccgatga tctgcaatcc aactggtaat ccttctgata
    34501 aacctgccgg tacagacata cctggaagtc cagccaagtt gacagggatc gttaagatgt
    34561 cactcatgta cattgtgatt ggatcgttaa tgttctcacc gattccgaat gcaactgttg
    34621 gtgaagatgg cccgatgatc aagtcataat ctgcaaagac tttttcaaaa tctcgtttga
    34681 tcaatgtacg gacttgtcct gcttttttga agtaagcgtc ataataaccc gcgcttaagg
    34741 agaatgtacc taacatgata cggcgtttta cttcttcacc gaatccttct gaacgtgagt
    34801 tgacatatac atcatctaat gatttcacat tttcagagcg ataaccgtag cggataccat
    34861 cgaatcgttg caaattggaa cttgcttctg atgaggcaat gatataataa acagccacac
    34921 cgtattttga atgaggcaag ctgacttctt ccacaacagc acctaatgaa cggaatgttt
    34981 ctgctgcttt caatacagct tcttttacgc caggggccac accttcgcct aagtattctt
    35041 taggtaaagc aatcttcatt cctttgatgt cgcctgtcag tccctctgca aaatcaggaa
    35101 ctgaaacgcc tgaagaagta ccgtcttttt cgtcataacc gctgatagct gtcaatgcta
    35161 atgcattatc tttcaccgta cgggtcattg gtccgatttg gtcaagagat gaagcaaagg
    35221 caatcaaacc aaaacgtgag acacggccat aagtaggttt catccctacg atgccgttaa
    35281 aagctgctgg ttggcggata cttcccccag tatcactacc taaagaaact ggaatttgtc
    35341 cagctgcaac tgctgctgca gaaccaccag aagagccacc aggtactttt gttgggtccc
    35401 aagcattttt tgttttcttg aaataagaag tttctgtact tccacccata gcaaattcat
    35461 ccatgtttag cttaccaaca gggatcatat ctgcttgata gattttatcc atgaccgttg
    35521 catcataaat tggttcaaaa ttgtaaagga tcttagatgc agcggttgtc aagatatctt
    35581 ttgttacgat attatccttg ataccaattg gaataccagc aaggacgttg ctttcatcaa
    35641 tccctttttc atctaaagct tttgcctgtt ccaatgcttt ttcttcgttc aatgtaatga
    35701 atgcctcgac ctcaggctct gtttctttga ttcgttcaaa tgttgttttt gtcaaatctt
    35761 gtacagtgat ttctttcgat acaagcatat gatgcagttc ttctagagaa cgattgtgta
    35821 attctgtcat tatgcgccag cctccccatt atcgatgatt gcgggtactt tgataaagcc
    35881 gtcttctgtt tccggcacat ttttcaataa ttcatcgcgg ttccatccag cttgcgcccg
    35941 atcttgtcgc atcacgttta ctgtttcaac cacattcgac gtaaatggaa caccttccgt
    36001 atctacttct tccagcattt caaccatatc gatgatttta cctaattggt cggtaaaact
    36061 tgcaagttct tcatctgcga acgcaagttt tgctaatttg gcaacgtgtt tcacttgttc
    36121 ttcactaatc gccatactac cccttctttc taaacgagtt aaaaactttg ctctctattt
    36181 taacacaaga gtgccgtgtc tgaaattgtt tattgaaatt tgtctgaaaa aactcatttt
    36241 tcattcttct actgagcgac ttttagccaa tgcatctgcc atttgatctt ctgtccaaac
    36301 ttcgattcct aattcttgtg ctttggtcag cttgctgcca gcatcttctc ctgctaccac
    36361 gatatccgtt tttttcgata cgctaccagt cactttcccg ccaagatttt cgatcgtctc
    36421 ttttgcttct tcacgagtaa atcgtgttag tttaccagta aggactactg ttttttcttt
    36481 aaaaggagac tcgacttctt gcaattgggc atttcgaagc cctttgtatt cgaaattgac
    36541 gcctgcttgt tttaattcat tcatcaattc atggacttct tcgttactga aataagtgac
    36601 tacactgtcg gcaatgatat caccgatcgt atcaagcgca ataatcgact catagtcact
    36661 tttactcaat gtttctagat caccgaaatg ttctgctaaa atttttgctg ctttcgctcc
    36721 gacatgtcgg attcctaacc cgaaaatcaa ccgctcgacc gaattatctt tgctgttgtc
    36781 gattgctgtc aaaatattat ttgctgattt ttcttttatt ttgtccaacg tcaataactc
    36841 ttcttctgtc aatttgtaaa gatcagcaac atctgctact agttttttat catacatctg
    36901 ttctagtacg cgcggcccca acccatcgat attcatcgca tttcttgaaa caaagtggtt
    36961 caaaccttct ttcatttgag cagggcattt aggattgatg caccgtaagg ctacttcttc
    37021 atccaaatgg acaagttcac ttccacaaac tggacaatgt gtaggcaatt ggtattcttc
    37081 gctgtcttta ggtcgtttat ctaacacgac ttgcgaaact tctgggatga tgtctcccgc
    37141 tttataaatc agaactgtat ctttcaagcg gatatccttc aacttaatat aatcaccgtt
    37201 atgcaggctg gcacggctta ctgtcgttcc tgctactcgg actggtgtca tgatagctgt
    37261 tggcgttact acccctgttc gaccgactgt ccattcgatg ttttcgatta gcgtttcaac
    37321 ttcttctggc ggaaacttgt aagctgctgc ccatctcggt gctttgatag taaaaccaag
    37381 ttgatcttgt agcgagaatt cattcacttt gatgacgatt ccatcgattt catagggcaa
    37441 atccacacgt ttgtcatgat attcttcaat gtatgaccac acttcatcaa tcgaatgaca
    37501 tagacgtttt tcccgattcg tgtggaatcc aattttttct agctcttcta gcgcatcata
    37561 ctgggttttt gcttgcatag gaccgaaatc agctactgtg tataaaaaag tgtccagatt
    37621 tcttttcgct gtgattttag aatctaactg acgcaaagaa ccagctgcgg cgttccgagg
    37681 attcgcaaag atatcttttc cctctgcttc tctgtcttgg ttcaattgga caaatgaccg
    37741 ttttggcatg aaacattcgc ctcttacttc gatgttcatt ggttctttta atttgattgg
    37801 gaccgaccgg acagttttta ggttttcagt gatgttttct cctacagttc catccccgcg
    37861 agtcgcacct ctcacgaaat ttccatcttc ataacgcaaa gaaacggaaa gtccatctat
    37921 ttttagttca cagcaatagt caactacacg tcccactgct ttttgtacac gttgatcaaa
    37981 agctatcagc tcttctttgc tgaaaacgtc gttcaaactg taaagcggaa tatcatgagt
    38041 gactttttca aaaccttcta atacttttcc gcctactcgt tgagtgggag aatcagacgt
    38101 gatcaaatca ggatattgtt cctcgattgc tactaattct gcgtattctt tatcataaac
    38161 atagtcttcc actgttggtt tatcttctac gtagtattcg cgagaccatt ggttcagtct
    38221 tgtacgaagt tcttctgctc gtttagcagc ttcgtcaatc gtcatttcat gttccatcat
    38281 ttaccctcca ctactaagct ttttcaattg gcgcaaaggc agccaaaaga cgttttactc
    38341 cttgacttgg gaaagccaca tctagttcta gatccttcga cgtcccgctt actcggacga
    38401 ctgttcctag accccatttt ttgtgtttga ctttatctcc aggtttccag ctgttatttt
    38461 cccctccagt agcactttta gagggaacaa ccgctgtctc tggctgttta tagctatatg
    38521 ctgttttttt agcgaataca ggcgtttttt taggcgtagg acgcatgcct tcgatttcca
    38581 gtaactcctg atcgatttct tctacaaaac gagaaggtcg gttatattgc gtccgtccat
    38641 ataatgttct ggagaaagca tttgttaaat acaacgcttc ttctgctcgc gtgatcccca
    38701 catatgcgag acggcgttct tcctccagtt cgctttcttc catcaatgct cgagataaag
    38761 gaaaaacccc ctcttctaga ccaatcagga atacaactgg aaattctaat cctttggctg
    38821 catgcaaagt catcaatgtc acttgggaag catcttcttc taaattgtca atgtcggaaa
    38881 caagtgccag atcatttaag aagaccgtta gtttttcttc tggtgcatca gcgtcttctt
    38941 cattttgctg ttcgaattgt ttgtcgaatt cttgtgtgac cgttaaaaat tcctccaagt
    39001 tttcgatgcg tgcttgtgct tctaatgtat tttggatttt taagtcttct agatatccgc
    39061 tacgatccaa aacctctttc gtcaattctg tcactgtcaa gtatgggatc atctgagtga
    39121 cttcttggat catctctcca aatgcaccta attgctgtcc tgcttttcca ccgatatttg
    39181 ccagatccac attttgcgct gcttcaagca gtggccattc atgaagagaa gcaaaactgc
    39241 gtagtttttc gatagatcct ggtccgatgc ctcgtttggg cgaattaacg atacgctcaa
    39301 aactgattga atcttgagga tttaccagca cattcaaata cgctaaaata tctttgattt
    39361 ctttacgatc gtagaacttg tgccctccaa ccattttata aggaatattt gctttcaaca
    39421 gagtttcttc cattacacga gattgtgcgt tcgtccggta caagatggca aagtcgccgt
    39481 aattccgatg attgcttcga atctcttctt gcatccggtc tacgataaaa cgggtttcgt
    39541 ctcgttcatt atctgcacgg tagtaagtga tcttgtttcc ttctttgttt tctgtccaca
    39601 agttttttgg ttttcgattg ctattgtttt caatgacttg gtttgctgcg ctaaggatgt
    39661 ttttcgtgga gcgatagttt tgttctagca aaattactgc agcatctgga taatcttttt
    39721 caaaatccaa gatgttctgc atatctgcac cgcgccagcc gtaaatactt tgatctgcat
    39781 ctcccacgac gcacaggttc ctaaatctac ctgccaataa attgactagc gtatactgtg
    39841 cgtgatttgt atcttggtac tcatctacat gaatataatg gaatttgttt tgataatacg
    39901 tgagtgaatc aggatgttct tcaaataatc gaatcgtatt catgatcagg tcgtcaaagt
    39961 ccatacattg attatattga agctcttttt ggtaagcagc ataacatttt gccgcaatct
    40021 cttcgtaata actgccttgc atttttgcaa aatcctgagg ggtctgcagg ctgttttttg
    40081 cttgagagat tgttcctaat atacttcgag gatcatattt tttcggatca atgttcagtt
    40141 cttttagtat ccgtttcatc aaggtcagct gttcagaaga atcgatgatt gtaaagttcc
    40201 ggttataccc gataaaatca acatctcttc ttaaaatacg cacacacatc gagtgaaaag
    40261 tcgataccca gacatcttcg cctccagatg cgagaatcgc attgacacgt tctttcattt
    40321 cttttgcagc cttattggta aaagtaatcg ctaggatgtt ccaaggattg acttcttttt
    40381 cctcaatcaa ataggcaatg cggtgtgtca gcactctcgt ctttccactt cctgcacctg
    40441 ccattagcag taatggtccg tcagtgtgaa gaacagcttc tttctgacgg gggttcatcc
    40501 cgtttaataa ttcagctttg gatgacatta acaacatcct ttcttttatc aatcttgtta
    40561 attatagcat tttcttggct ttcattaaac tagctagttc aaaatcattt gtttcttttt
    40621 atggattttt ccttgtcaat tcgttgattt cgcgctaaat taaaagaaag cgaggcgttt
    40681 gaatggaaaa aaaaggaaaa atcaagaaat tagataagac tcagatatat tttattctaa
    40741 aaggaatatt tgttggactg ctgacaggaa tcgtcgttag cctgtttcga ttatctatcg
    40801 aaaagctaag cgatttagtt cgaagtatct atgaaatgag tcgggaacag ccgatttact
    40861 taattggcct agctatttgc tgcatccttg cagcattttt cgtgggttat ctggtcaaaa
    40921 atgaaccgga tatcaaggga agcgggattc cacaagtaga gggacagctt cgcggggaat
    40981 tatcaatgaa ctggttctct gttttatgga aaaagttcat tggcggtgta ctttcagttg
    41041 gtgcgggcct ttttctaggt agagaaggac cttctataca gcttggcgca tccattggac
    41101 aaggagctgg acaattgttt cggagtccat cttcagaaga aaagatttta atttctagcg
    41161 gtgcaagtag cggacttgca gcagcattca atgctcctat cgcaggatta ctctttgttt
    41221 tagaagaaat ccatcactcc ttttctccac ttgtttggct gacatcattt gcttcagcaa
    41281 tcactgctaa cttcgtctct ctttactttt tcggcttgag acctgtttta tatctaggtg
    41341 accttccttc tttgccgttg aaatattatg gttccttagt gatcttagga gtacttctag
    41401 gcatcttagg ttttatttat cagaatgtct tgctggcttt gccaaaattt tacaaccgat
    41461 tgcctttacc agcttatttt cacgggttcg ttcctttctt gctgattttg ccaattggtt
    41521 atttatggcc tagtactcta ggcggaggca atcaaatcgt tttagctttt ggacatgctt
    41581 ccttgccaat cattatgatt atcggtttgt ttgttcttcg attcgttttt tccatgattt
    41641 cttacggtgg gggtcttcca ggggggattt tccttccgat attgacattg ggggctttaa
    41701 tcggtagctt ttatggaaac attatggttg atttcgggat ggatccaatc tacatcaagg
    41761 attttgtcgt tattgccatg gctggttatt tcacagcgat tggaaaagca ccgctgacag
    41821 caattatttt agtgacagaa atggttggct ctcttaatca tctgatgcct ttaggattgg
    41881 ctgctcttgt tgcttatatc gtcaatgacc ttctcggcgg taatccaatt tacgaatcat
    41941 tattggaacg tctacttgga aatactcaga ccgcctcact aaaaggtgca aggacaactt
    42001 ttgattttcc agtaacggca gagagttctt tagacggatt aatggtacga gacttcaatt
    42061 ggcctaaaaa tatgctgcta atctctatac gcagaggaaa tcaggaaatc ttgactcacg
    42121 gtgatacgat catgaatgta ggagatattt tggttatctt gactgatgaa gcaaacttgc
    42181 caagaatcaa gcaggaaatc gaggctaaat cttctatcac aaatttgaag caatcatttt
    42241 aacgaacatg gaaaaactat tttacaacaa ctattcatct acactacttg attctatatg
    42301 attctataaa aaaagaagag gctgggaaaa cccagcctct tcttttttat ttctatgctt
    42361 ctgctactgc aggagctttt ctcaataaac cataaatcac accagatacg actgctccga
    42421 tagcaataaa caccaaatac atgaccgggt gactcagtaa gaatacaacg aaaatcccgc
    42481 cgtgaggagc cagtaatttg attccgaaag ctccgactaa tccgccagtt aaagcagaac
    42541 caataataaa acttggaatg gcacgaatcg ggtcagctgc tgcaaatgga atcgatcctt
    42601 ccgtgacaaa cgatagtccc atcacgatgt tcgtcaaacc agcatcttga tctgttttgc
    42661 tgaatttatt cttaaacaaa cgtgtagcaa cgaaaattgc caatggaggt accattcctc
    42721 cagccataac agaagccatc acgacacttc cgccagttgc aacagtcgta gctaaagttg
    42781 ctgtaccaaa cacataagcg gctttgttga ttggaccgcc taaatctgcc gccatcattc
    42841 cagctaataa tgcaccaagt aaagcagcat tcgaaccact catacttgtc aagaaaccgt
    42901 tcaatgcatc attgattgct ttcataggga cattgaccag caacatcaag aaaccagtaa
    42961 tcagtaagcc aaacactgga taaaagagga tcgttttaat tccatccaat gattttggta
    43021 agttcttgaa taatttacgt aaaaatacga tgacataacc agctaagaat ccaccaatca
    43081 gtgcacctaa gaatcctgca ccgcctgtat tagctaatgc accagcagca aatccaacga
    43141 tcaaaccagg gcggtcaccg atacttgaag caataaatcc tgctaatacc ggcagcatga
    43201 aaccaaatgc agcttgtccg atttggttga accagctagc agcttgattg taattcccta
    43261 gatttgataa ttgatcatgt ggcacgccaa taaattggtc gatcatgaaa gaaagcgcaa
    43321 tagcgattcc tccaccaata acgaaaggta acatgtgtga tacgccgttc atcaaatctt
    43381 tgtaaattct ttgtccgata gtaccatccg catttccttc ttctgaactg ctttcttttc
    43441 catcaccatg gaatactggt gcagtaccac taagggctag attgatcaac tcttctggtt
    43501 tacggatacc atcactgaca ggacgattga tcagttcttt tccgtcaaag cgattcatct
    43561 ctactttttt gtctgctgca acgattacac cttctgcacg ggcgatgtct tcagcagtca
    43621 atcggttttt gattccttct gaaccgttcg tttcgacttt gatctccaca cccatttctt
    43681 tcgctttttt cttcaaagca tcttctgcca tgtaagtgtg agcgatccct gttggacaag
    43741 ctgtaacggc aacaacgaat tttctttctg gatgagcaga agcttctgca gcttgtgttt
    43801 cttgttctgc tttttcttct gcttcttttt gctcttcagc tgtttggaac aagtcttgga
    43861 cttcttctgg tgtatttgct tcttttaatt ttcctacgaa atctgcatca atcagcaatc
    43921 gagatagtgc tgctaatgct tgcaaatgtg tgtcgtttgc gccttctgga gctgcgatca
    43981 tgaaaaacag ataagttggc tgtccgtcta aggcttcata atctactcct ttttggcttt
    44041 ttgcgaataa aactgttgct tctttaactg cactgttttt cgcgtgaggc atggcgattc
    44101 catcaccaag acctgtagaa gtttgtgctt cgcgggctag aattccttct ttatatgttt
    44161 cgatatcgga aatccggccg gcatcaaaca ttttttggac catttcatcg attgcgcctt
    44221 ttttatcagt cgcttgcaaa tccatgatca tcgcttcttt gaccattaaa tccttgatat
    44281 tcatgattat cctccttgaa actaatcaat ttttgtgatt tcaacttctg gcagcaactc
    44341 atcaatcaat tcgcgagctg ccaagtcatc agaaaaagct gttgcgcttc cgcaagcaac
    44401 tccccattta aaggcttcga ttggatcttt cgtacggctg taagccccaa taaagccagc
    44461 aatcattgaa tcccctgcac ctactgaatt tttcaatggg cgaactaata cattcgtttt
    44521 ataagttcct tgttccgtga agagcaaagc accgtctcca gccattgaga tcagcacatt
    44581 ctgtgcccct tcagctagta attttttccc atacggaatg atttcttcta cagattggaa
    44641 ggttgtgttg taaagctcag ctaattcgtg attgtttggt ttgatcaaca acggtttctt
    44701 aacaagtgca ttttttaggt catcacctgt tgtatcaatc acgaaatctg cacctttttc
    44761 tcgaatgata tcaatcagtt cttgataaaa tccttttcgc aggctagctg gcgcgcttcc
    44821 tgacaatacg acgatatctc cttgtcctac tgttcctaat gcttgcttca actcatcgat
    44881 ttcttcatct gaaatagatg ggcctaagcc attgatctca gtttcagtgt ctgattttag
    44941 tttgatattg attcttgtat cttcttttac ggttgtgaac aaagactgga tttgttcttt
    45001 ttcaagccac ttcgaaataa attcgccagt gaaccctcct aaaaacccta gtgctgtaga
    45061 ttgagaatcg atccgtttca aaatacggga aacattgatc ccttttcctc caggtaactt
    45121 gaagtcttcc ttcattcggt tcaaatcgcc tagttttaac ccatctacgc gtacgatata
    45181 atcaattgat ggattaagtg ttactgtgta aatcattgta ttgcctcctt aattgttgtc
    45241 ttttcacgga attcattaac gaattctaat ggacaacgct cggttatgat cgtggctgct
    45301 tccaaaggtg caacagaggt gaaggacaac tggttgaatt tggtatgatc aatcaataca
    45361 aatgtctctt cggaattttt catggctaaa cgtttaacag ctgcctcttc tggatccgga
    45421 gtcgtgaatc cttgttcaag atgggcaccg ttcattccca taaatgcttt attaaaatga
    45481 aaatttttta gttgttctat cgcattagat cctaaaacag cattagttgc cagctttatc
    45541 gttccaccta aaataatggt agcaagctcc aaatcaacta aatttgccgc atgttgaacg
    45601 gaatttgtca ctactgtgat ctgttttcct tgcagaaaag gaatcatttc taacgtagta
    45661 gagccagcgt ctaaataaat gacatcttcg tcattaatgg tttcagctgc cgatttggcg
    45721 atttgctgtt tttcgtgaac gtttttgagt gatttttcac tcatattctg ctcaaaattc
    45781 aataattgct ctttcttagc tccgccatga actctttcta gaaacccact attctccagc
    45841 tcttgtaaat cacgtcttat cgttgattca gaagcattca aaaggtttac aagatcttgt
    45901 gatttcacga ttttctgctg ttcaagcaag tctaggattt tttgtctgcg ttcctctgta
    45961 agcattttca cgatcacctc aatacaaata atagcatatt ttttttctac tagcaatata
    46021 aatcagtcaa aaacgttcat aaaaattata aatcagtcaa aaaaaaaata aaaaaccagt
    46081 cagaaagact ggttttttat ttttttgtct atcatcaagc cgttttatcg ttttttattt
    46141 tcgcttcttg tttttttcat ataaacagaa gcaggttttc tttccttatg aagaagataa
    46201 taataaagtc ccatcccgcc aaacatgacc aaaaaaccga tgactgatcg aataggaaaa
    46261 ttaggaacaa aaaagagaca gacggataat aatgatgccg gaaccattat tcgataatag
    46321 agttgtttat ccattttctt cacctcatat tttttgtaaa gtaatcaatt gttctaattc
    46381 tcggtaatct aaaaattgca cacgcagatg ctgctcacct ttcttgacat cgaattggat
    46441 acttcgccgc tttttcttta ttcgtttgaa ggtaacatca gagagtctat gtttgatttc
    46501 ctttaacggt aattctgaca gggattctga aggaacatag attcttaagg ataaaagata
    46561 ctcttgatat ttttcatctg ttacctctac ttctagatat tccctaatat aataacaata
    46621 agcttcgatt ccattatcca aagcaacagt cggatcgata actttatagc acatcatgcg
    46681 tgatcgattc tcgtcaaccc aaggaaaata cgcctgagca tttagtgttc cgcgaacacg
    46741 cctttcttta taatctcctt gttggatatc ataacttttt gttacaaaaa atgaagcatt
    46801 ctttttagga acaggttgca tttgtgcatt ctgatactgg acagattgga tcgtatggtc
    46861 agtgtaaatg tattcaacga atggcggttt caataaaccg acaccattgt cccaagcaag
    46921 atgatcaaac ccaagctggt ccctaaaata ggattgaaac atttgattgt ttggcttttg
    46981 ccagttaaag gggtctcgat aaagctggat acatatgact tcgttttcta attccttcac
    47041 tttttctact tgttggatgt cgagaaaaat cggtttaggg atgatttgat gataatagcg
    47101 actataatac atttcccaac acgaagtgaa acataaacct tggtaaaaaa gatcgtatcc
    47161 tggaaattgg ttgcaatcga ctactacttc cccgttttgt tgtttcattt taggtaaatg
    47221 ttcgatttca tcctttttct caaacaatag ccgttgagag atctgttttg tattgtgata
    47281 gataaactcg ctataagctc gcatataggc gaacacccca tgagcaatca tttttttctg
    47341 aatgaagtct cgaatcaaaa attgcttttc tttgaaaaca gagatagaca atacattttt
    47401 tatcaataat tgattatctt ccaagcgaaa actacattcg ttctcgtcat ttcctacaac
    47461 taaccaactt tcgtctctta ccgatgctag cattattttt tcttgaagct ttcgaagatc
    47521 atacggatcc gcttgttgtg tgaaagagcg gataaatgtt ggctggatca acagacgtgt
    47581 caaaatagcc caatcgctta tttcctgttt tttttcttct tcatttaagt ctgtgagctg
    47641 gatagtcatc aataatttat cttcgccaat cattttctca cctctttcaa atctttttat
    47701 aatttaatta taaccaatga taaagaaaaa ctaaaacttt atgtcttaga aaccaatttg
    47761 gacgattaca tgatagacta agtaaaaaga aacaaagagg tgtttacaat ggggttgaaa
    47821 tttgaacgta cagataattt agataaactt ttcgaatcat ttgctgtcga tccggaaaaa
    47881 acagttgcac caaaagaaga gatcgatcga tttctaaaac cacagccaca aaatgaaaag
    47941 aaaaaagaca agaaacaaaa gtaagttaag ctcaaaaaaa gacttaccag ccaaactttt
    48001 atgaaagagt ttgactggta agtctttttt attcttttta tgattcaatt gcttgttcga
    48061 ttgctgccca cgcttcttct tttccctgtt ttgtaacgga agaaaagaga ataaacgtgt
    48121 cattgcgatc aaaatccaac gcttttttga tttcgctctc atgcttgttc catttaccac
    48181 gagggatctt atctgcctta gtggcaacaa caattacagg gatatcataa tacttcaaaa
    48241 attgatacat ctggatatct tcttgagaag gcttatgacg caaatctact aaagaaacga
    48301 ccgcacgtag ctggtctcta gtcgttaaat atgtctcgat catctttccc cattttgctc
    48361 gctcagtttt ggatactttt gcatacccat atcccggaac atcgacaaaa tgtaatgcgt
    48421 tctcgatcaa ataaaaattc aatgtctggg tctttcctgg cttaccggaa gtacgggcta
    48481 aattctttcg atcaatcaat gtgttgataa aagaagattt ccctacattt gatcgtcctg
    48541 ccagagctat ttctggcaat tgtgtatctg gatattgttt tggtgccact gcacttatga
    48601 taatttcagc ttgatggact ttcatggtct ctctccttaa caaggtgatg aataaagcaa
    48661 gcggctgtcg caaaagccaa aatgactttt acggcagcct cttttcatca acccgctttt
    48721 ttctctgaat ctttatagat tactgttggc tcaccagaca attcagctgc ttcttttgtg
    48781 ataatcactt tttcgatgtt ttcatttgaa gggatatcaa acatcacatc catcatgatt
    48841 tcttcaatga tggaacgaag tcctcgagca ccggtattgc gttcgattgc ttttttcgca
    48901 atggctctca acgcttcagg ttcgaattca agttcggtat tatctagaga aagaagtttt
    48961 tgatattgtt tgactagcgc atttttcggc tcagtcaaga tccgtaccag atcatctgtt
    49021 gtcaatttct ctaaagctgc cataacaggt aatcgtccga taaactcagg gatcaatccg
    49081 aattttagta aatcttcagg aatgatatgc tgcatgacac tttcgtcttc agaaagtttt
    49141 tggttttgtg taccaaatcc aatcgtcttt tcgcccatac gattcttcac aatcgtttcg
    49201 atgccatcaa atgcaccacc tacgatgaac aatatgttcg tcgtatcaat ctgaataaat
    49261 tcttgatgtg gatgtttacg tccgccctga ggtggcacac ttgcaacagt tccttctaga
    49321 attttcagca aggcttgttg gacaccttcg ccggaaacgt cacgagtaat agatacattt
    49381 tcgcttttac gcgcaatttt atcgatctca tcaatataga tgatcccttt ttctgcaagt
    49441 tccacattgt aatcagcaga ttgaagcaat ttaagcaaaa tgttttctac atcttccccc
    49501 acataaccag cttctgtcaa acttgtcgca tctgcgattg caaaaggtac attcaatgtt
    49561 tttgctaatg tttgtgctaa aaatgtttta ccagaccctg taggtccgat caagcagata
    49621 ttgctttttt gcagttcaac atcatctgtg ttttcttgtg cttgctgatt gacacgttta
    49681 tagtgattgt atacggcaac agctaacgag cgttttgcgc gatcttgtcc aatcacgtag
    49741 ttattcaata cttcaagaat ttctagtggt ttagggactt cagtgaattc gcgtacagct
    49801 tcttcataaa attcttcatc aatgatttct ttacataggt cgatacattc attacagatg
    49861 tagacccctg gaccagctac gatctttttc acttcttctt gggttttccc gcaaaaagaa
    49921 cagcgtacgg tctcattgct acttggattg tcatacatgg tcttcacccc ttaacttgca
    49981 aaaagtatgc aagaaactat caaagacttt acagtctttt actatcataa catagtttag
    50041 taaaaagaaa aagtgtttaa caaaggatca actgacctat acctttgcat tttttactct
    50101 taacaaaaaa taaggaactg tgacaaaatc gtgtcacagt cccttatttc gaataaacaa
    50161 ttttctagaa gtagcttctt cagaaatgat ttattacttg atttctattc tttcgcttct
    50221 gtcgctgtac ctgtgatcaa ttcgattgct tttttcattg tcacatcatg ttccagcata
    50281 tcttctgtca acacgcgttt gatttgttcg attggcatgt tgtatgtttc tgataattct
    50341 tggatttctg cattgatttc ttcttctgtt gcttgaagat tttcagcagc tgcaattgct
    50401 tcgatcacaa gatttgttct tgtgcgcatt tctgcttcac cttcgaattg tttatgcaag
    50461 tcttcttctg tagaaccagt taattgatag tacatttcag gagagatacc ttgacgttgc
    50521 atgttgttca agaattcgtc cattgaacga tgtacttcat catgaaccat cacgtgtggc
    50581 aattcaacga tttctgcgtt ttcaacagcc atacggatcg ctgcttcatc ttttgcatcg
    50641 tccgctgctt tttcttttgt ttctactaat tctttgcgat atttttcttt caattcgtct
    50701 aatgttgata cttcgtcatc aacatctttt gcgaattcgt catctaattc aggcacttct
    50761 tttgctttta cttcatggat tgtcactttg aagactgctt cttttccagc aagatcttct
    50821 gcttgataat cttctgggaa agttacattt acatctagac tttcacctga tttatgacca
    50881 actaattgat cttcaaaacc tggaatgaat gagcctgaac ctaattcaag tgagtaattt
    50941 tcgccttttc cgccatcaaa cgcttcgcca tctacaaagc cttcgaagtc gattactact
    51001 gtatcgccat tttcagctgc agcatcttct ttgataacta attcagcttg tgcttcttgt
    51061 tcacgtttga tacgtgcatc cacgtcagca tctgttactt cacggtcttg tttttcaaca
    51121 actagatctt tatattgtcc taattttact tctggtttca ctgttacttc agcagtgatt
    51181 acccagtctt gacctttttc catgctttca acatcgattt ttggttgaga aacaggatcg
    51241 atgccagctt ctttgacagc agcttcataa gcttctggta atacagcatt caatgcatct
    51301 tcatataaag cttcttcacc gtacatacgg ttgaatactt gacgagaaac tttcccttta
    51361 cggaatccag gtacgttcaa gctttttttc actttattaa acgcagttgt taatcctttt
    51421 tggatttcgt cttgcgcaat cgtaaatttt aaaacaccat cattcgtgcc ttttttttca
    51481 aatgttgcag tcatttaatt ccctccgagt ttagaaattc attttataca tcaaaaacgt
    51541 ttcatgcata cctttaaata gtacactaac cctttcaaat tgtaaacata ttgaatggat
    51601 agaatccttg tttttcataa catttttatc tttttcactg ataaaatcta atggaagaag
    51661 atcatttgct gcaaaatttt ttctcttttt tttaaaaaat cttgtttttc atcttctgta
    51721 ccttcataca tcgtttttcc tgtacacgcc tctacagtca gttgaaacca gcgcttcggg
    51781 tcttcgatgt atgtatcata gacaggataa acaattgcag attgcaacgt gaattcttct
    51841 tttaacacgg aactaagcag cgcatcttca ttcccgtaac gatctgaaaa tacacataat
    51901 tgctggtaac ttgcctgctg ctgcggcttt ggcagatctt ttggtatgac tttgactaac
    51961 ttttcttcaa tcgtcaaata gaaaacagga tggcattcgt tcaattgcct aagtgtctcc
    52021 agtaattttg cccttgctaa aatatggacc tctggcgata caataagttt actcgctgtt
    52081 tggataaact catgataagg aagctgttcg atctcatcaa tagacgcaag ctgacgtgca
    52141 ggttccaacg aaggaagttc ctccgattta ttgtggagtg ccttgatctt ctgcctctcc
    52201 atttgtccgg ataattcttc tgcaaattgg attttttcaa tgacccgctg ctcgaaagct
    52261 tcataaaaat ctgtacttgc tatcaatttt ctagcatata aaaaatcttg tgtactgatt
    52321 aacaagtcaa aataaaattc agcaaactcc tcattttgaa gatactgttt ttcatgcaag
    52381 agtgcttgct tcaatgcttc ttttttctcg tccaactcgt aaagacaaaa aacaagcagg
    52441 ctattagcct caaagctttc tttcaactcg taagctcgtt gaaataattc ttttgcctgc
    52501 tgatattgct ggtttgctag tgcttgttgt gccactcgca ttaaattctc atatttttct
    52561 ggaaaatcaa tcggcttcac gcagtgtcct cctcttgctc atattcagct catgttcaat
    52621 agtagcaaaa caaaaaaagc atgacaatta aaaataactg aagcaccctc taaaagctag
    52681 attttagatc tgacttttag aaggtgcttt caactgttac tgctttttat tgctcatcag
    52741 ctgttgactt cctggttgaa cgctttgatc agattgatcg taacaacact tgtattagtg
    52801 aaaaaatcgc ccagatgttg ctttttctga ttaaagactg ctggaagata ccctaacatc
    52861 agcaaaggaa attttagaat gaaccggcaa gcaccttctc taactaaaac ggttgaccag
    52921 ctaagttctt cttcatcaaa gctgatgact cgaataccaa agatcatttt cccaatcgtt
    52981 tggccatgat tgaatttcgt caataaaata aaatacgcta gataaataag taaggctgtg
    53041 aatccgtaga gactcagata agaatctgaa aaattaagcc aacctagatt tttggcaata
    53101 ccaagtgtta aacgcgtaat agctccgata cacaaaagat cgaccaagaa ggcaaacatt
    53161 cggataaaaa aacctgcata gaaatactta ggaaaatcat ttgcttttgg cggttcattt
    53221 cttgtgtccg tatacttttt ccatttacgt tgtttctttt tgatttcttc gggcgtcaaa
    53281 ggctctcttt caaaagagct cagtaccttt tgggaaaagt tggagtcagg tcctacagca
    53341 ggctgctgtt gcttatcttt ttcttgttcc ttattttcat ttgaaagctc tgacatgctt
    53401 actcacctcc gtaataatac attgcttttg gtgattccgc tgtccctaga ttctcaagaa
    53461 cggataagat ctgactagtc tcagaaggct tcaatccctg gaattctgct agtttacttc
    53521 ctaaccatgt actagcaaac ccagatggcg tggaagaata ttctactagt tccgcatctt
    53581 caagctgttg ttcctttcgt atagctttta aagcatcttc aggaaatccc aattcatcga
    53641 ctaaacctac ttcttttgct tggacaccat cataaatcct tccatcagca atttttttga
    53701 cttcttcttc agatttattc cgtccctcgc tgacgattgc tacaaaacga ctatatgcgc
    53761 tgtcgatata tgcttgaagc accgcttctt cttcttttgt ctctggtcgc gttcctgaac
    53821 ccatatcttt caacgctccg cttttaactg ttgtatcttc cacacccagt ttttctagaa
    53881 gtcctgaata attcaatcct gacatgatca caccaattga gccggtcact gtttcttctg
    53941 ttgcaaagat tttatctgct tgagcagaaa tatagtagcc accgctagct gccatgtttt
    54001 tcatgctgac atacattggg atatcatgtt ctttacgaat cgtatccaat ttcttagcga
    54061 tttccgcact ttcgtagaca ccgccaccag gagaatttac ttctaaaaag atacctttga
    54121 ctgttggatc ttcttcaatc gccttcagtt gttccataaa atttttatga ttgtaacctt
    54181 cagaagcaaa taaacctgaa gaccctcccg cagcaatcgt tccatctact gataatttta
    54241 cgattttttg cgtactgtct ccctcttcca acacatttgg agctagttct tcatccccat
    54301 ataaccaact gttcaatccc tcaatttgat cgttttcctg aggcttagtc aaactagctg
    54361 aaactaacga aaccacaaat aatcctgcag caatcagaac tgctgcccaa cgtcttttat
    54421 tcattctttc tcctttctaa tacaagtttt ttatgacgat cacagtttct gactgctcag
    54481 aagtgtcgaa ccgctctgct ttttcttccc gcgcataccc ggaaaacgac tcttttgtta
    54541 attcatcttc taccgtaaac tcacgagctt gagcaacttc caaggcatca ggtgcgattt
    54601 cttggatgct atcccagcca gtatctaaaa atattttcgt atcatctgat acaccagctg
    54661 atgcttcgaa tttggacaat tgttttttta acattcccag tgtcatgatc tcaatttttg
    54721 aatccatttt tactcctcct ctatccgatt actttctatt gtaccgaact cctgaaaaag
    54781 atgatagata aaaacccatt attttttgac ataaaaagga catttgacaa agaatttgat
    54841 atataccaat ttatttttta ttcttttttt gttgacaaga acattcgcaa aaggttatga
    54901 ttttaaatgt ttccagataa aaaacaaaaa ggaggatagt tatacctttt aggatagcgc
    54961 caggtctgtg taaacagatg acgaggagag ggtttatcga aagattcggc ggatggccct
    55021 agggactgca ctctacagaa aatccacaaa aaatgtctgc aaagataaaa caaaaggatt
    55081 ttcctgcagc tggaagcatt catacgaatt cattatagaa agtaggatgt tttttatgtg
    55141 cggaattgtt ggaatgattg gattaaaaaa tgtaacacca ggattgattg acggtctaga
    55201 aaaattagaa taccgtggtt atgattcagc tggtatcttt gtctcagatg gcacaactga
    55261 ttatctggtc aaagcacaag gcagaattca aaatttgaaa aacaaaataa atattgatac
    55321 tacaggaaat ataggtattg gtcatacacg atgggcaact cacgggcaac cttctgaaga
    55381 aaacgcccat ccacatactt cccaaagtgg acgcttcgtg ctcgttcaca acggcgtaat
    55441 cgaaaacttt gaagaactta aaattgctta tttagcaaat gaccacttta ttggtgagac
    55501 cgatactgag attatcgctc atctaattga aactttcgcg aaggatacta caacgcaaga
    55561 ggcgttttta aaagctttgc gggtcatcaa aggttcttac gctttcgctt tgattgatcg
    55621 gacagcacct gatgttattt acgtcgctaa aaataaaagt ccactattaa tcggactcgg
    55681 cgatggattc aatgtgattg ccagcgatgc aatggctatg cttgctcata cgaaggaatt
    55741 cgttgagatt gaagatgaag agatggttac cgtcacatca gaaaaagtta ttattcaaaa
    55801 ttttgcaggt gacatcgtag aacgttcttc attcgaagca caagtagatg cttcagatat
    55861 cgagaaaggt acctatcctt tttatatgct gaaagaaatc gacgaacagc ctattatcat
    55921 gcgtcgtatc gctcaaaaat acgtaacaga agacaatcgt gtctctcttg atcaaaagct
    55981 ggtcgataca ttgtctgata gcgatcgaat ctatatcgtt gcttgcggaa ctagttacca
    56041 tgcggggtta gcaggtaaac agactttgga aaaattgaca cagattcctg ttgaggttca
    56101 tttagccagt gaatttggct ataacacacc tcttctttca aaaaaaccat tctttatttt
    56161 cttgagtcaa agtggcgaaa cagcagacag ccgccaagtg ctggtaaaaa tcaaccgtct
    56221 cggctaccct tcacttacga ttacaaatgt tgctggttct actctttcgc gggaagcatc
    56281 ctttacactg ctattgcatg ctggacccga aatcgcagta gcatcaacga aagcttatac
    56341 tgcacaaata gctgtactaa ctttattagc caaagctatc ggtgataaaa aagaatttga
    56401 aacttctctt gtattcgata tcactcatga attgagttta gttgctaatg cgatggaatc
    56461 ggtcatcgcc caaaaagatt atttagaaga gttggcagaa gtatatctca gcgatacaag
    56521 aaatgccttt tacattggac gtggtgctga ctacaacgtt tctcttgaag ctgctttgaa
    56581 attgaaagaa atcagttata tccaggcaga aggttttgcc gctggcgaat tgaaacatgg
    56641 aacgattgct ttgatcgaag aaggaacacc agtgatcgga atcatcagtg aagaagtgac
    56701 tggtgcgcat actcgaggaa acctgaaaga agtcgaaagc cgtggcgcta aaacactagt
    56761 tattgtctca gagggattag aaaaggaaag tgaccagctg gtgctaccaa ctgtccaccc
    56821 ttatctaact actctaacca cagtcgtacc gactcaatta cttgcatatt acgcaacgct
    56881 attacgggga ttcgacgttg acaaaccacg taatttagcg aaatcagtga cagtagaata
    56941 ataaaagaac aaggaccagt gtcagacatc tgacactggt ccttgttctt ttatttttta
    57001 tgaaaatatc tcttaatcca gtccgatttc ttctttgact actgccgcga ttttatcgac
    57061 atagtaatta actttctcat cagtaggcgc ttctgccatc actcgaagta atggttctgt
    57121 accggaagga cgaactagga ttcttccttc tgatcccatt tcagcttctg cctcttcaat
    57181 cacttttttg attgccggaa catccatcgc accgttttta tcacttacgc ggatattcac
    57241 taatttttgc ggatagattg ttacctctgc tgcaagctct gataatttct tacctgtctg
    57301 tttcatgata ttcagtaact gaattcctga aagcatccca tctccagttg tgttaaaatc
    57361 taagaaaatc atgtgcccag actgctcgcc gccaaagtta taatcgtttt tgcgcatttc
    57421 ttctacaacg taacgatcac caacttgtgt aacgacatct ttcaaaccga ttccttccac
    57481 cgctttgtgg aatcctaagt tactcatgac agtcgtaacg atcgtatctt ttttcaatcg
    57541 atttttttct gccaagtatt tagcacagat aaacatgatt ttatcaccgt cgacaatgtt
    57601 tccaagttca tccaccgcaa taatacgatc gccatcgcca tcgaaagcta gtccagcatc
    57661 tgctcctttt tcaacgacca tctcagctaa acgttctgga tgggtagagc ctacgccgtc
    57721 attgatattt aacccgtctg gatttgtgcc cattgtataa aaatctgttt caagatcggc
    57781 aaacaaacga ttaacacttg ttgaagttgc tccgtttgct gcatcgacac aaatggtcaa
    57841 accggaaagg tcaccgttga tcgtttgtac aaggaattga gaatatttca ataagccttc
    57901 tggaaattct tctacagttc ccaatccttc agctgatgga cgaggcaatt catccacttc
    57961 agcatctaat aatgcttcaa tttctagctc ttggtcatct actagtttaa aaccatctgc
    58021 accgaaaaat ttgattccat tatcttgtgc tggattatga gaagcagaaa tcatgacccc
    58081 tgcgcttgct ttttgcaaac gtgtcagata agcaacacct ggtgtagaga tcacacctag
    58141 ctggaacact tcgataccca ccgataaaag tcctgaaatc agcgcttctt ctaacatttg
    58201 acctgagatt cttgtatccc gccctactaa cacgcgtggg cgttttcctt cttcttcatg
    58261 ctggcttagg acataacctc cgcaccgtcc cagcttaaat gcaagttctg gcgtaagttc
    58321 cttgttggct tcaccgcgta cgccgtctgt tccaaaatat ttacccatag ttgtaaaatt
    58381 actcctttaa cttaattttc tgaggaattt gttctgctca tttgtgttga ttcgcttgtt
    58441 tctgatgttt cttctgtact tgtggtcgag ctgcttgtcc cagattccga actggaagaa
    58501 atggttgttg tcgatggttc cgttcctgaa tcagcagatg aaatacttct actcgtactt
    58561 gtattttctt gtgtccgact gctcgtcgaa gcagagctac tgcttgacgt ttgcaacacg
    58621 ggtgtaatct ccacactaac tgattcgggc ttgatactta acccctcttc tactggtatt
    58681 tcaattttac gagttgttcg atgattgata cctgagacat tgatcggtac agcaatactg
    58741 tcaccgatcg atgcaagcaa atcgctagag ccgcttactt ctgcttccag ttttgaaaaa
    58801 ctgaaatcat agctttctac cccggcagct ggtgttcctt gctgtatccc ataaagtcgt
    58861 accgacttgc ttggcttgat cgaatcagct ctcactgtta cttgcactgg atcagagacg
    58921 atacttaata cttcccctgc tgcattcagc gcctgtattg ggacctcact attaatccca
    58981 tcatctgtga ccatcgaagc gtccacatca gctactactc gtttgatttc tgccaatgtt
    59041 ttgtcacctg tagtgataga gactttttta ggactaacgg aagtatcatc aagttcatat
    59101 ccagatggtg tgaacgttga aggaatcaac gtttccacat cgaaatcttt tattaccttt
    59161 ttctcaaccg ttactgtaat agtcgatggt tcgatctttg ctgtgacagc actgctcaaa
    59221 ttttgaattt ttagcggaac ttcatgtgtt ccttcgccca gcttagtgat atctgctgtg
    59281 acgcggaaca tccgtgtatc ttcgtttgcc tctgcattca actgaactcg gtttgcactg
    59341 gaaagtttga cagtcactgc attttcatat ccatggatat agtagcgctt tgaatcataa
    59401 gaaatcttga tcggcacccc cgtaactgtt tgattatacg cttcatttcc agaaagcgta
    59461 tttggaacgg actggccatt tgcattgaag tacagcgcaa tactgaacag caatgcaata
    59521 aaactgtaaa gaatgcttgt ccgtttctct tttgagatca tttgcgatcc cctcccttag
    59581 tcataccgtc taggaaagat tgaatcacgt ttttcttgtt ttttgttttc tcttcagcaa
    59641 ttagttctct acgcaagatt gccaaatatt cttgctggga taagccagcc atcagttcat
    59701 tatctaacgt gatgctgacg tccccggttt cttcagagac aacgatggta atcgcgtcac
    59761 tgacttcgct tataccgaca gctgcccggt gtcgagtccc gaattcttta gggatcaaca
    59821 tactttctga tagaggaaga taggcgcttg ctactgcgat ctttccttct tttacaataa
    59881 ctgcaccgtc atgcagcggt gtattaggaa taaagatatt gatcagcagc tccccagtga
    59941 tatctgcatc taaagcaatc cctgtctcaa tatactcatc taatccagta tgacgttcga
    60001 tagtgatcaa cgcaccgatt tttcgcttgg acatatattg gatggctttg tcaaaagaca
    60061 agatcatctt ctcatcttcc tgctgttcgc tttttgattg tttgaaaagc gaactgcgtc
    60121 caagatgttc cagtcctctc cggatttccg gctgaaaaat cacgatagca gctatcaccc
    60181 cgtacgtaat gacttggttc atcagccaag acaaggtgtg cagaccaatg atttccgcta
    60241 cgattcggat aacaataaaa atagctacac ctttcagaag ctgaatcgct tttgtgcctc
    60301 gcagcagttg gatcagtttg tatacaagat accagacaac cagaatatca agtatgttca
    60361 ccaaaaaatt cagagagaac aagtcaccgg aaaacatttg ctgccaatag tccaaattaa
    60421 aaagttcccc gatttgaaat gacataaaaa gcctctcttc tcttttgaga tttcctctct
    60481 agtatatcat atgttttaat tttagaggct gatatgctcg tatttttctt gagaaaaacg
    60541 cataattttc aagaaaattg caagtatgcg ttttattttt ctctgcaata aatattttta
    60601 aacttcagag aattattcat tatatttttt ctgttatttt tccttttttt cttttgtagc
    60661 ttgttccatt tttttacgtc gttctgctct ggcagctctt ctagcagctc ttctttcttc
    60721 tgcttcaagg tccgtcgttt tttcttttct agtcttaacg ggtacatcga tagattcctc
    60781 tggttcaagt cgtttcttga ttttttctaa ttctcccgtc agtgcagcat agttgtaaaa
    60841 acgtgtttta gcgtcgtgga cagtcttttc aaataaagct tttgcaagat ttggatttgc
    60901 gttatctagc gaggaaaagc gaacttgttt cctcatgaaa tcaggcatag cagagaaatc
    60961 aggttttttg tagtccaaag tcattgggtt cttgtttttt tcgaccattg tagggttata
    61021 tcgatataat gaccaataac cagaagaaac agcttctttt gcttctttaa gcgattcttt
    61081 cattccgcca agcaagccat gtgtgataca aggcgtatag gcaataatca gagaaggacc
    61141 aggatacttt tctgcttctt caaatgcctt gatcgtttgc atttgattgg cacctgaagc
    61201 aatttgcgcc acataaacat ttccatatgt catcgccatc attcctagat ctttctttga
    61261 agcatacttt ccactagccg aaaatttagc gattgccgaa gctggtgttg cttttgaggt
    61321 ttgaccgcca gtattggaat agacttcgtt atccaaaaca aggatattca cgtctgctcc
    61381 gctggcaagt acatgatcga tcccgccaaa accaatgtcg taagcccatc cgtctccacc
    61441 aatcatccat tggctgtttt ttacgaatag atcctttctc ttgtatatat cctccagttc
    61501 agggaaaatt gatcgttcgc tttcgatcgc agcttgcagt tttgctgctc tttgctgcgt
    61561 tccttcactc tcaaacatgt gtactaacca gtcttccatc aattctcgta gttcttctga
    61621 tacttttggc aatacttctt tgattgaact tgccaaagcc tcgcgacgag tctgtgccgc
    61681 tagaagcata ccataaccaa attcagcatt atcttccaat aaagaatttg accatgcagg
    61741 cccttgacca cattcattgg tcgtataagg agaagcagga gaagcaccgc cccaaataga
    61801 agaacagcct gtcgcattcg cgatcatcat tcgatcaccg aacatttgtg tcaataattt
    61861 tacataaggt gtttcgccac agcctgagca agcgcccgag aattcaagaa gcggttgatt
    61921 gaattgtgta gacaagacag tattctttcc tttgactgga tttgcttttt gtcttaatgt
    61981 cattgcaaaa gcccaattca cagcttgttc tttctgttct tcataaggct tcatcactaa
    62041 agctttttct tttgcgggac aagcctctac acacagacca caacctgtac agtcttccac
    62101 tgaaacttgg atacggtatt ttacgccgtc tgcgcctcgc atttctctca cgataaatcc
    62161 ttctggcgct tcttccattt cctcttcatc tgctaaaaat ggacggatgg cagcatgagg
    62221 acaaacaaag gcacattcat tacacatcgt acagcgatca ctaatccact caggtacttc
    62281 taaagcgacg ccccgctttt ccatagaagc cgttcctaaa ggcatttcgc cagttgtcat
    62341 tccatttgct acaagtgtac caacagagag ttgatttcct tcctgtgcat tcactggttc
    62401 aagtatttct tgtatataac cagtgttcct tttattgatt ttttcaggca tctccaacgt
    62461 tctccaatgg tctgggatcg cgacttgatg aagcagttcg gtcgtccgat cgattgcttg
    62521 tatgtttttt tctacgatag ccattgattt atgtccatag cttttcaggg cttcttcttt
    62581 tagcagcgga agcacctcat caaaaggaat gatgtcagct aatttaaaaa aagccgtttc
    62641 cattgccgta ttgatccggc gtcccaaacc gacttcttgg gccaatctca tggcattgat
    62701 cgtatagaat ctaatgttat tttcagccaa gtaacgtttt aattttaagg gcagatgcgt
    62761 ttctaattgt tcgtcgctcc aaagagtatt caataaaaaa atgccacctg gcttcaatcc
    62821 tttgaccaag tcatagctat gcaggtaagc tggtgtgtga caggcaacaa ggtccgcatg
    62881 ctcgacaaga tacgctgaac gtatcggcgt atctccaaaa cgaagatgag agacagtcag
    62941 accgccagat tttttcgaat cataataaaa atagccttgc gcatatttat cggtgtgatc
    63001 tccaataatc ttgatagctg atttatttgc tccaactgtt ccgtcagatc caaatcccca
    63061 aaacttggcc tggaatgttt gcggttctgt caaatccaga ctttcctttg gttccaaaga
    63121 ttgataagtc acatcatcca cgatccctat ggtaaaccgt tttttgcgta tgcttgggtc
    63181 ttttttcaat tcatcaaaaa ctgctgagat ttggtcggga gtcacatctt tagaccccaa
    63241 tccgtagcga ccaccaataa cagccgggcg aagttcagaa tcatataacg cactttgaac
    63301 gtctaataag agaggttctc cacctgcccc tggttcttta cttcgatcaa gaacagcaat
    63361 tgtttttact gtatgaggca acttttgcac gaatgtttcc actggaaaag gacgataaag
    63421 atggatattc aaaaaacctg ttttccgtcc gtttgcattc aagtaatcaa tcgtttgttc
    63481 aatcgtctgt gcaactgatc ccatagaaac aatgacttct tccgcatcgt ctgctccgta
    63541 ataagtcacc aagtcataag aagttcctcg taatcggttg atctctttca tatatttttg
    63601 aacgatttca ggtaatttat cataataggg gttgatcgtt tcccgttgtt gaaaatggat
    63661 gtctggattc tggttcgtac cactaacagt cggatgattg ggattcatcc ctcgtttacg
    63721 aaatgaagct aatttctcct gattgatcag aggagctaat tcttcatatt ccaaaacttc
    63781 gattttttga atctcgtgac tcgtacggaa tccatcaaag aaattcaaaa aagggacttc
    63841 tccttcaata gaagcaagat gggcaacagg tgctaaatcc atcacttctt gtacactgct
    63901 ttcagctaac atagcaaatc ctgtttgtct tgcagccatc acgtctccgt gatctccgaa
    63961 aatattcaac gcatttgtcg tcactgcccg actagcaacg tggaaaacac ttggcagtag
    64021 ttccccagca atcttgtaca tattcggtat catcaaaagc agcccttgtg aagcggtata
    64081 tgtagttgtc agtgcaccag ttttcaatga tccatggacc acaccagctg ctcctgcttc
    64141 ggattgcatt tctactactt ttactggttg accgaatacg ttttcttttc ctgctgctga
    64201 ccattgatct actaattcag ccatggtcga actgggtgtt attggatata ttgcagcaat
    64261 ctcggtaaat gcataagaaa tatatgcggc tgccgtattg ccatccattg ttttcatttt
    64321 tcgcatgatt catcatcctt gttcatattc tctcttatta tctgttccat tataacgtaa
    64381 aacatgccat ttttttcttt tatttataaa aatattttac atgtatctat ttgaattggt
    64441 catctaattt ttagacaaac agtctaaatc gttgcctttt tttgtcagac atgtataaac
    64501 tataagcgaa agaggtgttt taacatggat atatcagtga ttgatgcaac gaaaacaaat
    64561 acacaaaaag gaatccttta tggttcatcg aatgctccta aaaaaatggt cgaattcatc
    64621 aacttagctt gtccgtattg ccgacaatgg tttgaagaat cttatgagct attagaagaa
    64681 gcagtccaaa gcgggcaatt gcagcgagtg atcaaattgt tcgataaaga aaaagaaagc
    64741 ttacagcgag ggaacgtgat gcaccggtat ctcacaatca gcgatggcca aaaagcgatc
    64801 aaagagatca aacaaatatt cgatactcaa gacgagtgga aacatctttc tctccaagaa
    64861 gtagcggatt ttgcagtaga taaactaaag ctgacagaac aaaaagacga acagctgagc
    64921 caagctgtca tcaacgaagc tgagcaagca catattcgat ttgttccaac tgtcatcttg
    64981 ggtaaagaaa tctttgatga atctatttca atagaggaat taaaagaatt gatccaaaca
    65041 aaataaaaaa ataaggagcg tg
//
LOCUS       DAJSMK010000007        62320 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.007, whole genome shotgun sequence.
ACCESSION   DAJSMK010000007 DAJSMK010000000
VERSION     DAJSMK010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 62320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.007"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            598..1287
                     /locus_tag="ON488_000452"
     CDS             598..1287
                     /locus_tag="ON488_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3230671.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1274..2482
                     /locus_tag="ON488_000453"
     CDS             1274..2482
                     /locus_tag="ON488_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCR3230672.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2776..4047
                     /gene="serS"
                     /locus_tag="ON488_000454"
     CDS             2776..4047
                     /gene="serS"
                     /locus_tag="ON488_000454"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HCR3230673.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="ON488_000455"
     CDS             complement(4596..6080)
                     /gene="guaB"
                     /locus_tag="ON488_000455"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HCR3230674.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6585..7280)
                     /locus_tag="ON488_000456"
     CDS             complement(6585..7280)
                     /locus_tag="ON488_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HCR3230675.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="ON488_000457"
     CDS             complement(7370..8470)
                     /gene="ychF"
                     /locus_tag="ON488_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HCR3230676.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8479..8670)
                     /locus_tag="ON488_000458"
     CDS             complement(8479..8670)
                     /locus_tag="ON488_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HCR3230677.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8691..9581)
                     /locus_tag="ON488_000459"
     CDS             complement(8691..9581)
                     /locus_tag="ON488_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HCR3230678.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9568..10335)
                     /locus_tag="ON488_000460"
     CDS             complement(9568..10335)
                     /locus_tag="ON488_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCR3230679.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="ON488_000461"
     CDS             complement(10347..11060)
                     /gene="rsmG"
                     /locus_tag="ON488_000461"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HCR3230680.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="ON488_000462"
     CDS             complement(11292..13193)
                     /gene="mnmG"
                     /locus_tag="ON488_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HCR3230681.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="ON488_000463"
     CDS             complement(13210..14607)
                     /gene="mnmE"
                     /locus_tag="ON488_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HCR3230682.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14906..15289
                     /locus_tag="ON488_000464"
     CDS             14906..15289
                     /locus_tag="ON488_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230683.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15457..16215)
                     /locus_tag="ON488_000465"
     CDS             complement(15457..16215)
                     /locus_tag="ON488_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HCR3230684.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16233..17051)
                     /locus_tag="ON488_000466"
     CDS             complement(16233..17051)
                     /locus_tag="ON488_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCR3230685.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="ON488_000467"
     CDS             complement(17048..17404)
                     /gene="rnpA"
                     /locus_tag="ON488_000467"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HCR3230686.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="ON488_000468"
     CDS             complement(17522..17656)
                     /gene="rpmH"
                     /locus_tag="ON488_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HCR3230687.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18179..19513
                     /gene="dnaA"
                     /locus_tag="ON488_000469"
     CDS             18179..19513
                     /gene="dnaA"
                     /locus_tag="ON488_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HCR3230688.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19711..20841
                     /gene="dnaN"
                     /locus_tag="ON488_000470"
     CDS             19711..20841
                     /gene="dnaN"
                     /locus_tag="ON488_000470"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HCR3230689.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21070..21312
                     /gene="yaaA"
                     /locus_tag="ON488_000471"
     CDS             21070..21312
                     /gene="yaaA"
                     /locus_tag="ON488_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HCR3230690.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21299..22423
                     /gene="recF"
                     /locus_tag="ON488_000472"
     CDS             21299..22423
                     /gene="recF"
                     /locus_tag="ON488_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HCR3230691.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22420..24366
                     /gene="gyrB"
                     /locus_tag="ON488_000473"
     CDS             22420..24366
                     /gene="gyrB"
                     /locus_tag="ON488_000473"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HCR3230692.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24386..26857
                     /gene="gyrA"
                     /locus_tag="ON488_000474"
     CDS             24386..26857
                     /gene="gyrA"
                     /locus_tag="ON488_000474"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HCR3230693.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27093..27392
                     /locus_tag="ON488_000475"
     CDS             27093..27392
                     /locus_tag="ON488_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HCR3230694.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27442..27954
                     /gene="ssb"
                     /locus_tag="ON488_000476"
     CDS             27442..27954
                     /gene="ssb"
                     /locus_tag="ON488_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCR3230695.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27980..28216
                     /locus_tag="ON488_000477"
     CDS             27980..28216
                     /locus_tag="ON488_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HCR3230696.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28359..30332
                     /locus_tag="ON488_000478"
     CDS             28359..30332
                     /locus_tag="ON488_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HCR3230697.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30338..30790
                     /gene="rplI"
                     /locus_tag="ON488_000479"
     CDS             30338..30790
                     /gene="rplI"
                     /locus_tag="ON488_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HCR3230698.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31064..32431
                     /gene="dnaB"
                     /locus_tag="ON488_000480"
     CDS             31064..32431
                     /gene="dnaB"
                     /locus_tag="ON488_000480"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HCR3230699.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33211..34503
                     /locus_tag="ON488_000481"
     CDS             33211..34503
                     /locus_tag="ON488_000481"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HCR3230700.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35239..36102
                     /locus_tag="ON488_000482"
     CDS             35239..36102
                     /locus_tag="ON488_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCR3230701.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36231..37853)
                     /locus_tag="ON488_000483"
     CDS             complement(36231..37853)
                     /locus_tag="ON488_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3230702.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38102..38623
                     /locus_tag="ON488_000484"
     CDS             38102..38623
                     /locus_tag="ON488_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCR3230703.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="ON488_000485"
     CDS             complement(38809..40539)
                     /gene="spxB"
                     /locus_tag="ON488_000485"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HCR3230704.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40704..41522
                     /locus_tag="ON488_000486"
     CDS             40704..41522
                     /locus_tag="ON488_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HCR3230705.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41625..41822)
                     /locus_tag="ON488_000487"
     CDS             complement(41625..41822)
                     /locus_tag="ON488_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230706.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41991..42569
                     /locus_tag="ON488_000488"
     CDS             41991..42569
                     /locus_tag="ON488_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCR3230707.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42664..42801
                     /locus_tag="ON488_000489"
     CDS             42664..42801
                     /locus_tag="ON488_000489"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230708.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43614..44117)
                     /locus_tag="ON488_000490"
     CDS             complement(43614..44117)
                     /locus_tag="ON488_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCR3230709.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44476..45501
                     /locus_tag="ON488_000491"
     CDS             44476..45501
                     /locus_tag="ON488_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCR3230710.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45848..46726
                     /locus_tag="ON488_000492"
     CDS             45848..46726
                     /locus_tag="ON488_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HCR3230711.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47202..47318
                     /locus_tag="ON488_000493"
     CDS             47202..47318
                     /locus_tag="ON488_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCR3230712.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48246..48584
                     /locus_tag="ON488_000494"
     CDS             48246..48584
                     /locus_tag="ON488_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230713.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48678..48908
                     /locus_tag="ON488_000495"
     CDS             48678..48908
                     /locus_tag="ON488_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230714.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49308..49679
                     /locus_tag="ON488_000496"
     CDS             49308..49679
                     /locus_tag="ON488_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HCR3230715.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49953..50645)
                     /locus_tag="ON488_000497"
     CDS             complement(49953..50645)
                     /locus_tag="ON488_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCR3230716.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50648..51433)
                     /locus_tag="ON488_000498"
     CDS             complement(50648..51433)
                     /locus_tag="ON488_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR3230717.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51670..53070
                     /gene="lacG"
                     /locus_tag="ON488_000499"
     CDS             51670..53070
                     /gene="lacG"
                     /locus_tag="ON488_000499"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HCR3230718.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53095..53412
                     /locus_tag="ON488_000500"
     CDS             53095..53412
                     /locus_tag="ON488_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HCR3230719.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53425..55098
                     /locus_tag="ON488_000501"
     CDS             53425..55098
                     /locus_tag="ON488_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HCR3230720.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55112..56743
                     /locus_tag="ON488_000502"
     CDS             55112..56743
                     /locus_tag="ON488_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HCR3230721.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57615..58805
                     /locus_tag="ON488_000503"
     CDS             57615..58805
                     /locus_tag="ON488_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HCR3230722.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58939..61128
                     /locus_tag="ON488_000504"
     CDS             58939..61128
                     /locus_tag="ON488_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3230723.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            61125..>62320
                     /locus_tag="ON488_000505"
     CDS             61125..>62320
                     /locus_tag="ON488_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCR3230724.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVR"
BASE COUNT        19421 a        11324 c        12304 g        19271 t
ORIGIN      
        1 ttcatcagga gtgtttcccg attcgttttt ggctgccgta gcaactttta tatcatatca
       61 gagagacaag taattgtcaa ctctttttta aaagtttttt cgatttcgtt tttcgaaatc
      121 ttccagcaac tcatttatca taacttatcg tttgttattt gtcaagaact tttttgaagt
      181 ttttttcgat agaatcaagc ttcgcaagtg gttctttttt aacgactcag ttatcttatc
      241 atgtcatttc caacatgtca acaacttatt ttttattatt taataagtta ttggtgttct
      301 tttgaacaaa taataatata tcaacatcac atgtgaaagt caataagaaa atgcttattt
      361 atcaacattt ctagcttaca tgatcattgg ttagttctgg tcctttttcg ttcgtcttta
      421 taactccgag agacgtaaaa tccttttgtt ttcagtttaa tgttcatgtt cttgtcttat
      481 tcacaccaac tagatgtctc accttctaaa attttcctta acaaagtgct gcttttatct
      541 atttctgctt ttttttgcta gaataatagt aacaatatga ctctggagga tttatttatg
      601 aaaattttga ttgctgacga tgataaagaa atcgttgaat tattaagtat ctatgttcac
      661 aatgaggggt atgaagcagt aaaggcttat gatgggaaag aagcattatc taaaatcaga
      721 acaatccctg atattgaatt acttatttta gatatcatga tgcctgagat ggatgggatg
      781 caagtagtga aagagctacg aaaagaatcc caaataccaa tcattatgct gacagcaaaa
      841 actactgata tggataagat caaaggactg gtcgctggtg cagatgatta tgtgaccaag
      901 ccatttaatc cgttagaagt aatggctaga gtaaagtctt tattacggcg tacaaaaatg
      961 cagattgccc cagatcagcc tgatgtatta gaagtaaatg cattaatcat caataaagac
     1021 tctcatgaag ttaaaacaat cgatgggaaa gaaatccagt taacagcttt ggaattcggt
     1081 atcctctact tgcttgctag tcatcctaat cgagtattta gcgcggatga aatttttgag
     1141 cgtgtttgga aacaagaaag tattgtctct gctaaaactg tcatggttca cgttagtcat
     1201 ttaagagata agattgaaga agcaactggt ggtgaaaaag tcattcaaac cgtttgggga
     1261 gtgggctata aaattgacgc aagatagtaa acgagcaact gaaaaacgcc gtcggatcaa
     1321 tttgacttca aaagaaatca gcgaattgtt agcggaagga atcatcacga ttatcctttt
     1381 gcttctatta aatgtttcta ttctggttgt tatcagttcg gtgatcaaca gttcaccttc
     1441 tttgacgaat gcgatttggg attcaaagaa tatttttgca gaacgattga acactgattt
     1501 gttctggaac ggccggaatt ttattattcc ctttttcttt ctattagata ttggtgtttt
     1561 gtattggcgc ttgattcgaa gatatcgcca aatgcaattg cggcatatca tcagcgaact
     1621 tcactacatc gcaaacggaa attatgatca tcgtatccct tttgaactga gtggtgactt
     1681 aagccgagtg gtaacaagta tcaatggatt ggtggatagt accgtagcag cgattgaaga
     1741 cgaacgtaaa atcgaaaaat caaaagatga attgatcacg aatgtcagtc atgatatccg
     1801 taccccactc acgtccatca ttggatacct aggactgata gaagatggcc agtatcactc
     1861 agaagaagat cttttaaagt atacgcatac tgcttatatc aaagcaaagc agatgaaatc
     1921 tttagtggac gacttatttg aatacactaa ggtacgccag cctgctgtcc cggtgaattt
     1981 ttctgccttt gacatgatcc agttgatcga acagttagca gctgattttg agttggaagc
     2041 ttctaaaaaa aatatccaaa tacttgttca atcaaaagta gactccctta tcatggatgg
     2101 cgataccgaa aaacttgtac gtgtcttcaa taatcttttg acgaatgcgt tgaaatacgg
     2161 aaaaggagca acgaagatcg taatcgaagt agaacgtatc ggttcagaag ttgttgcaac
     2221 agtcaaaaat aacggagcaa tgatcccaca acaggcaatc gataatctat tcgaccgttt
     2281 ttatcgtgta gaagaatctc gttcacaagc aactggagga actggacttg gtttagcaat
     2341 cgctcaaagc attgtggctt tgcacggcgg atacatttat gcaaaatcag ataagcaatg
     2401 gacttctttc atcatgcacc ttccaatcaa gaaaaatgaa aaattaccta ttgatacaca
     2461 ggaagttatt gacgaaagct gaaatattcg ctattcttat tacaattatt agaataaatg
     2521 aaaaacacag aacccagtac actttattct ttttcagaga gctgatggca ggtgtaaatc
     2581 agcaaaggat aatttggaag ttccagttcg tttacgtgcc ctttcgaaat aagaaaggtc
     2641 ggttcaacag ccgttatgtg ttcaacaagt gcagctgacg ctgaacttgg gtggtaccgc
     2701 gaatttcaga ctgattcgtc ccaagaataa tgggatggat cagtcttttt ttattttcaa
     2761 aaaggaggaa atcatatgtt agatgtaaaa atgatgcgac aaaatattga agaagtacaa
     2821 gaaaaattga tgactcgggg cgtaaaaaaa gaaacattag ctgaattcat ggaactagat
     2881 gaaaatcgtc gtaagctact agtcaaaagt gaagaattaa aaaaatatcg aaatgatgtt
     2941 tctgctgaga tcgcccaatt gaagcgtgca aaagaagatg cttctgctaa aatcgctgaa
     3001 atgaaagaag tcggtggcaa catcaaagca ttggatactg aaattgctga agtggatgaa
     3061 aaattgaaac aaattgcaac tactttgcca aaccttcccc atgattctgt gccagttgga
     3121 acagatgaag aggacaatgt agaaatccgt cgttggagcg aaccacgtac atttgctttt
     3181 gaaccaaaac cacactggga aattgcagaa aatcttgata ttttagattt tgaacgtggc
     3241 gcaaaagtag ccggtagccg ttttgtctat tacaaaggat taggtgctcg attagaacgt
     3301 gctgtctaca acttcatgct tgatcagcat atttacgaac acggctatac tgaaatgatc
     3361 actccttata tcgtcaacag taaagcgatg tttggtacgg gacaatttcc aaaattcaaa
     3421 gaagatgttt tccaattgga gaatactgat ctaacattaa tcccaacagc tgaagtacca
     3481 ttaactaact attataatga tgaaatttta gatggtgcag atttacctat ttatttcact
     3541 gcactaagcc ctgcttttcg ttctgaagcc ggaagtgctg gtcgggatac acgaggactg
     3601 attcgtcttc accaattcaa taaagtagaa atggtcaaat tttcggatgt agagcattct
     3661 tacgaagaat tggaaaaaat gacagctgat gcagaagata tcttgaaaaa attgcatttg
     3721 ccttatcgtg tgatggcctt atcaactgga gacatgggct tttctgcagc taaaacttat
     3781 gacttagaag tatggatacc tgcacaagat acttatcgtg aaatcagttc ttgttctaac
     3841 tgtgaagatt tccaagcacg ccgcgcaatg atccgttatc gcgataatga tggaaaaatc
     3901 cactatactc atactctgaa tggttcagga cttgcagttg gccgtacagt agctgccatt
     3961 ttggaaaact accaaaatga agatggttct gtcacagttc cagaagcgct cgttccttat
     4021 atggggaatc tgaaagttat taaataaaga ggctgtgaaa aagccgctta gtttcgagta
     4081 ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaattgga cttaataccg
     4141 agaaactggc ttttgaacac catttatcga gaggttgtga aatcagcgaa ttaacctgag
     4201 tattagagaa aaaaatggaa aaatagtccc tcatatttta ccgtttgttg aactaatacc
     4261 gagggtcagc tgattgaaca ccgtttagtg gagaggtcgt aagcctaccc cccagctcct
     4321 agttacaagg acaaattcaa aaaacagctc ttcatatttt atgaatgttg tacttgtgat
     4381 tcggaggtgg caagggaaca ctgtttattc aaaaagaggc tgggacagaa gcgtttaact
     4441 ccaagaaata agaagaaatt cacgaaaatt gcttttcaaa tttttgtgaa tttcttctta
     4501 tttccgaagg agttgcttct acttccgccg tttatacgtg tttagagcgt gagacaaaag
     4561 tgttctttac ttttgtccca cgctctttaa tgtttttaag attcaactga atagtttggt
     4621 gcttcttttg tgatttgtac atcatgaggg tgtgattctt ttaatccact gccgctcatt
     4681 tggataaatt gcgcttcatc acgtaattgc tgtagattgg ctgccccaac ataacccatt
     4741 cctgaacgca aaccgccgat catttggaaa ataatatctg caacacttcc tttataagca
     4801 acccgacctt cgattccttc tggtactaat ttatttgctt cattgacact accttggaag
     4861 taacggtctt ttgaaccttt ttccatcgcg cctaatgagc ccatacctcg gtatgttttg
     4921 aatcgacgtc cttggaagat ttcgaattca cctggtgatt catctgtccc tgccaacata
     4981 cttcctagca tcactgcatg tccgccggca gctaatgctt tgacgatgtc accagaatat
     5041 ttgatccctc cgtctgcaat aatcgctttg ccatattgac gagcaactga tgctgcatca
     5101 taaatagctg tgagctgagg tacacctaca ccggctacca cacgtgtcgt acaaatcgat
     5161 cctggtccga taccaacttt tacgacatct acacctgcat catataaagc ttttgtcgct
     5221 tcagccgtcg caacgtttcc tgcaatcaat gttgcatctg caaaagttga acggatttct
     5281 tgaatttttc ggatcacacc tgcactatgt ccatgagctg tatcgatgat gattgcatct
     5341 gcccctgctt ctaataaagc attcgcacgc tcaaatgtat cgcttgttac accaacggct
     5401 gctgctacaa gcaatcgacc atgttcatct tttgctgcat ttggaaattc gatcactttc
     5461 tcgatgtctt tgatcgtgat caatccgctt aaacgacctt cgttatctac gattggtaat
     5521 ttttcgattt tatgtttttg caaaatcttt tctgcatctt ttagagaggt acctactggg
     5581 gcagtcacta agttgtcttt tgtcatcaca tcagcaatcg gcatgtgata atctgttaca
     5641 aaacgcatgt cgcggtttgt aattatccct accaattttc tgttttcaag tgtttcaacg
     5701 attggcacac cactgatacg atatttgctc atcaattctt ctgcgtctgc tacaagatgc
     5761 tgtggcgtta agaagaacgg atcaatgatt acgccacttt cagaacgttt gacttttctt
     5821 acttcatccg cttgctggct gatcgtcatg tttttatgga tcacacctag tccgccttgt
     5881 cttgccatag caatggccat cttgctgtcg gtaacagtat ccatacttgc actgatgatt
     5941 ggaatattca acttaatatt tttagctaat tgtacgctca tatccacttc gtttggtaac
     6001 acgtgacttt ctgctggtat caataagaca tcatcaaaag taaatccttt tttcgtgaac
     6061 tttgtttccc agttggacat ttttagtacc actcctctaa tttagtttat ctattaaaat
     6121 aattgatttt ttcatttaag tcaatgatct acttggaatc aagttagctt tctcatagaa
     6181 taccaatata aagcgtttac atctgtgtat attaaaagag attgtaaaaa agctgtcctg
     6241 catcaagtaa taagaacagc caatcaaaaa cagcttctca tgtttttgaa ttggttgggt
     6301 ttattaccgc agatgcaaac ttttgaacac cgtttagtgg agaggctgtg aaaaagctgc
     6361 ttagtttcga gtagtaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
     6421 ggacttaata ccgagaaact ggcttttgaa caccgtttat cgtaaaaagg gactgtgaca
     6481 agacttttgt cacagtccct tactattatt taactatgga taaacaaaat gaggttcttt
     6541 actaccccta gatatctagc aaaatagctg atctttttgc tagtttatct tcttgggacg
     6601 gataaacttc caataatccc gtattttttc ttcaagtagt aacggattgc taaagcagtt
     6661 gccccgataa tgataactac tactggatct aatactggat tgataactgg tggcaatagt
     6721 gttgtcgcag aaaacagtac gacccaaaga agtgtcgttc cacctaggat aagcaatgtc
     6781 ttacccattc ctggtttctt gcttcgatct gctccgggat attcatattg atagatgtat
     6841 ttgtacatca tataaaagac ccagccaccg attgcagaac ctagaacgag tgtagaaaag
     6901 ccataagctg gcgttgttcc acgtgaaaac aatccggtaa tcgcaatcat gatacttaat
     6961 agaccaagca acagcaacgt attatctaac cacatcaata aaggggtgga tgaatttttt
     7021 acttctgctg gcttattgat gattgcttcc gttctttcag agactgtccc aaacaattga
     7081 cgggctgttc ttccgccttt ttgttctgca actaaagtag gcagaatgtc atgaagggct
     7141 tttacttttt cttcttcaga caaattcgct gcttctaaag attttttcaa atcaaaaatg
     7201 tactgttgat ttcttttggt taattttgtt tctaaactat tgttttcttt tacgattgct
     7261 cgtaattgtt ctggttccat tatctaatag tcctccttag ccgttccttt tctcaacggt
     7321 cgtcacaaaa gacattctac catattctac agctagtttg atagcccttt tacacattaa
     7381 agcggaataa cattacgtcg ccgtcttgta cgacataatc ttttccttct aatcgaacac
     7441 gtccagcttc ttttgctgca tgcatgtttc cgtaatgatc caagtcttca aaagagacag
     7501 tttctgcacg gataaatccg cgttcgaaat ctgaatggat gattcctgct gcttgtggtg
     7561 ctttgattcc ttttttgaat gtccaagcac gtacttcttg ttccccagca gtaaagtaag
     7621 tagctaagcc taacaaatca taagcagcac ggatcaactg atccaaacct gattcttcga
     7681 ttcctaaagc ttctaaaaat tccgctttgt cttcttcatc taattctgcg atttcttctt
     7741 ctgcacgagc actgaccacg atcacttctg cattttcttc tgcagcaaag ttgcgcactt
     7801 cttgtacata atgattcgcg tctgcatctg ctacgtcatc ttctgagaca ttggctacat
     7861 aaagaattgg ttttgtcgtc aataaaaata gtgatttaac gattttttgt tcttcttcag
     7921 taaattcgat cgttcgggca gattttcctt cttccagtac aggtttgatt ttatccagta
     7981 cagctagttc tgccactgca tctttatctt tggttttagc aacttttgct acacgagtat
     8041 agcgtttgtt gatagattct aagtctgcta acactagttc caagttgatc gtatcaatat
     8101 cttctagtgg atcaacacgt ccttctacgt gagtaatatt atcatcatca aaacagcgaa
     8161 caacgtgaca aatagcgtct acttggcgga tatggcttaa gaattgattt cccaaacctt
     8221 ctcctttact tgcgcctttt acgattccag caatatctgt aaattcaaaa gtcgtcggaa
     8281 cagttttttt cggatgtaca agttctgtta agcgttgcaa acgccagtca ggtacttcta
     8341 ccatccctac gttggggtcg atcgtcgcaa agggatagtt tgctgcttct gctcctgctt
     8401 ttgtgatcgc attaaacaaa gttgattttc ctacgttggg caacccaaca attccagcag
     8461 tcaatgccat aaatttattc actctttctc tgcatttttt tcaattactt tttttaattt
     8521 cttttcaaaa tctcgacggg tcatcatgac gatatgtccg caattcatac atctgatttt
     8581 gatatctgcg cccattcgaa tgacttccca gcgattcgtc tggcaagcgt gaggtttttt
     8641 catttcaacg atatcgtgca agtcgtacat aaaaatagcc tcctttttgt ttattcttca
     8701 tcaaattgaa tattcaagat atcaagaatt cgagtcaaat ctttttgaga aagatattca
     8761 atctcgatct tacctttccc atttttttct tggatagcta cacttgtacc aaatttatcc
     8821 atcaaacgat cttcgctttc tcggatataa tatggttttt cctttgctag ccttgggatt
     8881 tttttctttt cttttccatc attttgattt aactcagaaa caagctgttc cagttggcgg
     8941 acagttaaat tttcagttac tgcacgattg gctaatttca agatcaatgt tttatttttt
     9001 aaacctaaca gcgtacgggc ttgtcccata gataaacgct gatcttgtac catttccttg
     9061 acaagatccg gtaaagaaag caagcgcaaa taattggcga tataaggtct gctctttcct
     9121 aaacgactag ctacttctgc ttgtgttagt ttcaggtttt tcatcagcat ctcatatgct
     9181 tctgcttctt ctaacggatt cagatcttct cgctgcaagt tttccagcac tgctacttgc
     9241 atcatcgctt cttcgtcaaa gtctctaacg atagcaggga tcgtttcttt ttcagctagt
     9301 ttggacgctc gaaaacgtcg ctcccctgca ataatctcat atccttttac tgcggaacgg
     9361 cgtacgatga tgggttgaaa gacacctgat tgttcaatag aattagctag ttcctgcaaa
     9421 gatacttctt caaatgtttt acggggctga tacggatttg gtcgcagctc attcaatggt
     9481 agctggacaa cggtatcatc ttttacatcc accgtctcta agttttctaa atcttgaaac
     9541 agtgcatcga ttcctcggcc taatccttta cttttcttca cgacttacca cttcctttgc
     9601 caatgcttgg tagacttcag ctcctcgaga acgtggatcg tagtcgatga tcggttttcc
     9661 atgactaggt gcttctgata aacgaatatt tcttggaatg atcgtttcgt aaactttttc
     9721 gcggaagtat ttacgtactt cttctacgac ttcatttccc agatttgttc gtgcatcata
     9781 cattgtcagt aagactccct cgatctctaa ttctggatta aagtgttttt ggactaaacg
     9841 aaccgtattc agtaattggc ttaatccttc caatgcgtaa tactcacact gaacaggtat
     9901 caaaatcgaa tcacttgctg taaatgaatt gattgtcaga tggccaagag aaggcgggca
     9961 atcgatcaaa atataatcat actgactgct tacttctgct aaagatcctt ttaatcttga
    10021 ttctcttgcc atcattgacg tcaattcgat ctctgctcct gctaattgga gagtcgcagg
    10081 cacaatactc aaattttcgt gttcagtgat caaagttgcc tcatcaattg gcaattcatt
    10141 gactagaaca tcatagatgt ctcttgtcac atcaggtttt ctgatcccga caccactggt
    10201 agcatttcct tgtgcatcca tatccactag caatactttt ttgccaaggc tagcaagaca
    10261 agcacctaga ttcaccgtcg tcgttgtttt gccgacgcca cctttttggt tcgcaacaga
    10321 tattatttgt gccatctctt ctcctcctat ttgattggct gcttattagg cagtccgggc
    10381 tttcttgggt atttctttgg ggttggtttc tttttttgaa taacgatgat atgccgttga
    10441 tcagagacat tcggcaaggt aaccgcctct tctttgagga atttaccacc taataaagca
    10501 atcgcttgtt ttgcttctgt caattcctct tcactttttg ctgctttcaa tgcataaaaa
    10561 tagccttctt gtttagccaa gggcaaacac aattccgcta acacattcaa acgagcaacc
    10621 gcacgagcag tgacaaggtc aaatgatgca cgaaagtgag gattttgccc aaatgtttct
    10681 gcccggtcat gatataagga agcatcgatt cctaataatc gggttaactc agataagaag
    10741 gttattcgtt tattcagaga atcaacgatc gttatctgca gttctggaaa ggcaattttt
    10801 aaaggtatgc taggaaaccc tgcccccgaa ccaacatcgc ataaagataa aggttgcgta
    10861 aagtctactt caaatgctaa tgtaagtgaa tcgtaaaaat gcttcagata tacgtctttt
    10921 tcatccgtaa tagctgtaag gttcatcttt tcgttccatt cgactaatgt ccgataataa
    10981 atagcgaatt gattcatttg atgatcggta agctctatcc ctttttctgc caaggattgg
    11041 cgaaattctt ctggtatcat aaatattcct ttcattgtga aacagcaatt gtttcacaga
    11101 ttctctccct actttaacgc aaaatctcta gacatgcaat ccttccatat ggattcttaa
    11161 aaatttgaaa agtaagaaaa gccgatagac tttttctttc tagtatgact cataaaatat
    11221 acacagaaga gagaactagc tttgagcaat ttctgcaaaa actagttctc tcttctattt
    11281 attattacgt attacgctgg ttcactgact ttcgcaatct tcccttgttc gatatagacc
    11341 attaggatac ttaggtctgc agggtttacg ccactgattc ggctagcttg ggcaattgtt
    11401 tctggttgga ttttctgcaa tttttgtttt gcttctgttg ctaatccgtt gattgctgcg
    11461 tagtcgatgt tttctggaat ctttttcgct tccatgcgtt ttaatttttc tactttttcc
    11521 atggcttttt tgatgtagcc ttcatatttg atttggattt ctacttgttc gatttctttt
    11581 cgtgtcaatt cttcattttc tggaataaac cgtagaagtt ctgcataagt aatctcagga
    11641 cgtcttaaaa agtcgcttgc tagtacacca tcttttaatg gtgccgcatt aatcgttgct
    11701 aaaaagtctt ggacttcttc tgttggtttg attcgtacat tcatcaaacg tttgatttct
    11761 tgttcaactg cttctttttt cttcaaataa ttcttgtatt gatcttcttt tactaagcct
    11821 acacggtgac ccatttctgt taatcgcaaa tctgcattat catgacgtaa aagcagacgg
    11881 tattcagcac gtgaagtcag caaacgataa ggttcgttcg ttccttttgt taccaaatca
    11941 tcgatcatga caccgatgta accgtcactt cgtttgatca ctaaaggttc ttttccctga
    12001 actttcaaag ctgcattgat accggcaatc agcccttgtc cagccgcttc ttcataaccg
    12061 cttgtaccat ttgtttgtcc agctgtataa agattttcaa cgactttagt ttctaatgtc
    12121 ggacggagct ggtgtggctc tactacgtca tattcgatag catatcctgt acgcatcatt
    12181 tctacttttt ctaatccagc aatagaatga agcatgttga cttgaacatc ctctggtaaa
    12241 gaagtagata aaccttgaac atagacttct tccgtattta agccttctgg ttccaaaaat
    12301 aattgatgac gtggtttgtc tgcaaaacgc acgatcttat cttcgatgga tggacaatag
    12361 cgagcgccta ccccttcaac gatccctgta aacattgggg cacgatgtaa gttgtctcga
    12421 ataatttggt gagtcgtctc acctgtatag gtcagccagc aagattcctg atctagttta
    12481 taggcactat ctggtgtgct gaagctaaaa tgattcggct ctttgtcacc aggctgctct
    12541 tctgtaacag aatagtcgat cgtacttgat tttactcgag gcggtgttcc tgttttgaac
    12601 cgttcgatag caaagccaag ttcttttaga tgattcgcta gtccaataga aggttgagag
    12661 ttattcggac ctgatgaata tttcaattca ccgataatga tttctccgcg aagtgctgtt
    12721 ccggctgtaa taacaactgc tttggcccgg tagctcgctc ctgtggacgt cactactcca
    12781 tgacaaacac catcttcgac gatcagttct tcgacgattc cttgtcttag cgtcaaattt
    12841 ggttcttttt cgatcgtatg tttcatttct gttgaataag catgtttgtc tgcttgtgct
    12901 cgcaatgctc ggacagctgg gccttttcct gtgttcaaca tacgcatttg gatataggtt
    12961 ttatcgatat tcttacccat ttctccgcct aacgcatcga tttctcgaac gacaacgcct
    13021 ttagctggtc cgcctacaga aggattacat ggcatgaatg ctaccatgtc caaatttatt
    13081 gtcagtaata atgtttttga tcccatacgt gcagcagcaa gtgcagcttc tgaaccggcg
    13141 tgtcctgcgc caacaacgat cacgtcatac gcatctgctt cataatgttc caatcgtttg
    13201 ttcctccttt tattttccta aacaaaattg actgaataat tgagtgatta gctcatcttg
    13261 tacactgtcg ccgacaactt ctcctagata gtcccagcaa cgcgtcatat ctatttgaac
    13321 gagatccaca ggcattcctg aatcaatacc tgcaatgact tcttcaagtg agagggaagc
    13381 tttttctaac aacgcgatat ggcgggtatt agaaacataa gtagcgtctc tttctcctgt
    13441 ttctccgctg aagaataaat cagaaatagc tgattccaaa cgatctagtc cgtcgttttt
    13501 agctacggaa attgaaaaaa ctggttcatt ttcgatcaat ttcttcaatt tttcttgttc
    13561 cagctgtgct ggcaaatctg ttttatttag aagaatgatc cgtttcaatc cacttgtcgc
    13621 ttccaataat tgttcatctt ctgctgtcag tggttcgctt tggtttagaa caagtaagat
    13681 caagtctgct tctgctaatg cttttcggct tctttcgacc ccgatccgtt ccaccacatc
    13741 ttctgtttcc cgaattccag ctgtatcgat tagcttgagc ggtacccccc gaacattgac
    13801 atactcttcg attacatctc gagtcgttcc tgcaatatcc gtaacgattg ctttttcttc
    13861 tcttaacaaa tggtttaaca aacttgattt gccgacattt ggccggccga tgattgccgt
    13921 acttaaccct tcccgcagaa ccttcccttg cttggatgta gcaagtagcg cttggattct
    13981 ttgttggatc atctgcgctt tttcaagcaa taacttcgta gtcaattctt cgacatcatc
    14041 atattctgga taatcaatat ttacttctac ttgtgctaat gtctctaaaa tctcttgtct
    14101 caatgagcgg atcaaagcag acagattgcc gtctaactga ttaagagcta gtcccattgc
    14161 tttgtctgtt tttgcccgaa tcaaatccat cacagcttct gcctgtgaaa ggtcaacacg
    14221 accattcaag aatgctcgtt ttgtgaattc gcctggctca gctaatcttg caccttctct
    14281 taacaatagc tgcaaaattt gattgactac aacgatccca ccgtgacaat tgatttctac
    14341 tacatcttcc cgcgtaaatg tctttggtgc tctcatcacg gagaccatga cttcatcgac
    14401 aagctgattg ctcttgggat caacgatatg tccataatgg atcgtatgac ttggtacttc
    14461 tgataatcgt ttgtttccag attgataaac tttatctgct agttgcacag cttgatcgcc
    14521 acttaaacga acgatactga ttgcaccttc tccaggtggg gtagaaattg ccgcaatcgt
    14581 atcaaattct aaagtaattt cagccatttt ttcacttcct ttttcatttt gcgcacaaaa
    14641 aaagtgccca ctccaccctt tatgcacaat aaacggtgaa cttcgcactt tgactgcttg
    14701 ttcttgatta aattctggtc atagattatc acacttgcta taaggaatca agtgtttaaa
    14761 acaattagat gaagttgagc ctgttctgct tccattacct tatatttaat tgtccttgga
    14821 tgtctctttg cgttctttgg tttattcgaa gagaagatac tgtataaaca aggctttatc
    14881 tttcttaaaa aaaacggtac actaaatggt agcgctatct aaactataca cttttgaaag
    14941 gagaaaatat gtgagcccgt tcagatctgc tgcattggaa gaagaaagtg accctcggat
    15001 caacgatgtc gttttatcta cagggaatat caaccagaaa tatatcgtcc gcgatatcgt
    15061 ttttgttgtg gaatgcttag aagctgattt gtttgaccca tcttttccca aagatgacct
    15121 tttcttaaca acgaagagga aattaaagac gaaggtactt gaatatggtg cgaatgcagt
    15181 aatcaactgt cattttgagt atcagcaaaa aaaacgcgac ggaaagtatt ttctggaact
    15241 ttttgcttat ggaacagtga tccaatttat ccaaacaacg attggttaaa tgaaacagac
    15301 aaaaaaagcg gatcaaaact gaagacagtt tcgatccgct tttttctatc aaagttagtg
    15361 actacttcat cgtatactct gataagaatg atttctagta aaatatactt ggtttgaaaa
    15421 actttgtcaa cgtgatttat tcaaaaagta atggaatcaa taatattttt tagcaggttc
    15481 tactactaaa taacgataag gttcctcacc ttccgaatgt gtttttacat gttcatcttt
    15541 gcttaatgca gcatggattt gtttacgttc aaatgcaggc attggttcta agaaaacagg
    15601 ctgccctgtc cgttttactt tttcagccgt gcgatcagct aaacgctgaa tgatctcttg
    15661 gcgcttttca cggtaattgc ctacattgac tactacagac agcttatttc ttgctaaacg
    15721 atggatgaag acttgtgcca gatattgcaa tgcattcagt gtttttccat gtttcccaat
    15781 cagtatgcct tgcttttgtg tttctaaatg gaaaacaacc atattatttg attctctttc
    15841 cattttgaca agagctggag catcaagctg ttttgaaatt tcagtaagat aaactgccaa
    15901 ttccgttaaa gctgcttcat cacctagctc acttacttct tctgtttttt cttcaagaat
    15961 cgtttcgttg actacctcga tctcagctgt tggttcttct tccaaaattt cttctacagt
    16021 ctgttctact gtttcagaaa ctttttcgct gatacttggc tggatcgaaa gccgtgcatt
    16081 ctttcgaccc attcctagga aacctttttt tccttcttcc agtatttcga tttcgacttg
    16141 gtctttggcc aaacccaaat cagccagacc tagttggaca gcttcgtcta ttgttgcagc
    16201 ttcataaatc ggcattagca ttacctcccc tattatttcc gttttttctt aggattcatt
    16261 gctttcttaa gagcacgttc tctttcgcgg attctccgtg cttcttcttc acgctctttt
    16321 cgaattttga aagggttgtt gatcagcagc gtttgtacaa cttggaaggc attggaaact
    16381 acccagtata atgaaagacc gctggctaaa ttgacaccca tcactaaaat cattacaggc
    16441 atcacgaaat tcatgatctt cattgatgca ttcgattcaa tttgactcat gctagataaa
    16501 tacgtacttg caaaagtaaa gattgctgct aaaatcggca aaataaatgt tggatccgcg
    16561 ttccctaagt tcaaccataa gaaatgccct tgtttcaact ctggtacacg tgaaatagat
    16621 tgccataacg ccatcaagat tggcatttgt actaataaag gaagacaacc agcatatgga
    16681 ttgacgccat tttctgcata taaacgctgc tgctcttctc ttaacttact ttgtgtttcc
    16741 ggatctcttg aactatattg ttgctgcagt gcttttaatt tcggttgtaa ttcttgcgtt
    16801 ttacgcatgc tctttgtttg gaaatgcatc aacggcaata ggatcacgcg gatgatcagt
    16861 gtaaataaaa tgatccctat ccctgcatta ccaaatgaca acgccttgat cgcctcagca
    16921 aagtaataaa caatataacg atcccaaatt cctgtactct gtgcgctgac ttccccagtt
    16981 ccgcaaccgg ataagacgat gaccaaacta acgataccgg ccatcaaaag taaacgtttg
    17041 tatttcttca cttactcttt tcctctctgt cgattatttt tgcaagtttt aagacgtgga
    17101 ctaaattgga gcgaacctca tcataagtca accccttcac acttggtcta gcaatcacaa
    17161 taaaatccaa ctccggatca atttcttctt ttatagaata aactgctgct cggatttttc
    17221 gtttgacttc attgcggttt accgcgttgc cgaccttttt tcctacagat aaaccaactc
    17281 gaaaatgagg ctgtcccggt ttttccaaac ggtaaacgac gaatttgcgg ttagcaaaag
    17341 aatctcccgt atggaacacg gcttgaaact ctcgttcttt ttttactcga tacgcttttc
    17401 tcattagttt tctttccttt tctatctctc acttacgctc ataatcatac cataattacg
    17461 attgtccttt catcatttcc ctaaaaaaga gtataaaaaa aaccactgaa accccagtgg
    17521 cctaagctga aagaactttt cttcctttgc gacgacggct agctaacaca cgacgtccat
    17581 ttttagtact catacgttta cggaatccgt gaactttttg acgtttacgt ttatttggtt
    17641 ggtatgttct tttcatatat tccacctcca aaatgttctt atctatttta taaacacaga
    17701 catactttga tagtataacg acaaagtagt gattttgtca atataaaata gaagatcgat
    17761 tgttaaaact tatccacaag attatttttt tctatgggaa tcctatgtgg aaaaagttat
    17821 gcacagggat tatccacaga taataaaagg ctggttttac acagaaaaca cacgtgtaaa
    17881 aaaagtaatc cacaatcagg cgatttcctg tgtattccgt ctcctaacta ttggtatatc
    17941 tgtatttttt atccacagac gcaagaggaa atctattggt ttttacgagt tttccacctg
    18001 tgcattagtg gtgtggaaaa ctttttttga caactgtgtt tttctctttt ttctttttgt
    18061 cgattgtgtg gataattgta attaaaaaat ttttttcttc ggtttctgtg gaaaactatt
    18121 gaaaaaaatg ctaaattagt actagttatt cactttttaa tgaaggagga ggccttatat
    18181 ggtatccctc gatgctttat ggaatgaatt aaaagcaaca taccaaaagg atttatcgcc
    18241 tgctagctat aatacatgga tcgaaacagc gaaccctcga acccttgatc aaaaccagct
    18301 cgttgttgag gttcctagca agattcataa agaatattgg gaaaaaaacc tggcgacaaa
    18361 aatcgttgaa gtcggttata tgttatcagg aaatgagatt atccctcgct ttattactgg
    18421 cgaagaagca gagcaagaag aagttataga agaaaaaaat ccaaaagttg tggcacctag
    18481 tccgctaaaa aaagccatgc tgaaccctaa atataccttt gatacgtttg tcattggtaa
    18541 aggaaaccag atggctcatg cagcagcgct cgttgtagca gaagatccag gttctattta
    18601 taacccgctc ttcttttatg gaggcgtggg acttggtaag actcacttga tgcatgcaat
    18661 tggtcatcaa atgctgcaaa gtcagcctaa tgccaaagta aaatatgtaa gcagtgaaac
    18721 ttttgctaat gatttcatca attcgatcca aaacaaaaca gcagaagagt tccgtcaaga
    18781 atatcgaaat gttgatttac tgctagtgga tgacattcaa ttttttgcag aaaaagaagc
    18841 tacgcaagaa gagtttttcc atactttcaa tgccttgtac aatgaaggga aacaaatcgt
    18901 actaaccagt gatcggttgc caaacgagat tccgaaactg caagaacgcc ttgtttctcg
    18961 ctttgcatgg gggctgtctg ttgatattac accgccggat cttgaaacaa gaacagcgat
    19021 tttacgtaaa aaagcggcgg ctgaacgtct agagatccca gatgacacac taagctacat
    19081 cgcaggacaa attgattcta acattcgtga attagaaggt gcgcttgttc gagtgcaagc
    19141 ttttgctgcg atgaatagtg aagatatttc gactagtcta gctgcagacg cactgaaaac
    19201 gttaaaatca ggaaaaggac atcctcaatt gtcaatcctg cagatccaag aagaagtggc
    19261 aaagtattat cacatccaat tgaaagatct caaaggaaag aaacgcgtca aatctattgt
    19321 tgttcctaga caaatcgcta tgtatttggc acgtgagctc acagataatt ctttaccgaa
    19381 aatcggagct gaattcggtg gcaaggatca tacaacggtt atccatgctc atgaaaaaat
    19441 ccagcagctg atggattcta gtgtcagtat gcaaaatgaa gtatcagaaa tcaaaaactt
    19501 tttactaaat taatttgtcg attctatcaa ctgaaaatag catgtggata aaagaaaaaa
    19561 acgttcaaaa gttatacaca ctttttccac agctgttttt tcgtttctct cttacgtttt
    19621 ttgagttttc cacagaatca acatgcccta ttacttttat tattcttttt aactaataat
    19681 aaataaacaa acattcaaag gagatacatc atgaaagtta ctttaaaccg agctagcttt
    19741 atgcaggaat tgcaaactgt tcaacgagct atttcaagca aaaccacgat ccctattttg
    19801 acaggtgtaa aaatcacact gacacaagaa ggtttgactt tgacggggag caacgctgat
    19861 atatcaattg aaactttttt gtctgttgaa aacgaaaaag caaatatgca aatcgaatct
    19921 actggttcca ttgttttaca agcacgtttc tttagcgaaa tcattcggag acttcctgaa
    19981 gaaacattta ctttagaagt tttagaaaat aaacaagtag cgatcacttc tggaaaagcg
    20041 aattttatcg taaatggatt agatgcagat aactatcctc atcttcctgt tgtcgaaagc
    20101 cataaccaga tgaaattacc tgtacacgta ttgactaaac taatcaacga aacagttttt
    20161 gctgtctcac aacatgagag tcgtccaatc ttgacaggtg tgcatttcat tttatctgat
    20221 aattctttat tagctgtagc tactgattct caccgtctaa gtcaacgcgt gattccagta
    20281 gaacaagcgg ctgatcattt tgatattgtt attcctggaa aaagtttgat cgaattatct
    20341 cgctcattaa caaatgaaga agaaatcgtc gaaatcagca ttatggaaaa ccaagtgttg
    20401 ttcaaaacag aaacgatgta tttctattcc cgtttgctag aaggaaacta tccagatacc
    20461 aatcgtttga ttccttcaag ttttaataca gaggttgaat tttctgttcc tagcttttta
    20521 gcggcgatcg aacgggcttc tttactttct catgaaggcc gtaacaacat cgttcgttta
    20581 tctattcgtc cagatgcggt tgttttatac ggaaattcgc cagaaatcgg gaaagtagaa
    20641 gaaagcttga gttatacagc aagcagtggc gatccattag atatttcttt caatccggat
    20701 tatatgaaag cagcgttgcg tgcatttgga gatatgagca tcaaagtgaa atttatctct
    20761 gctattcgtc catttacatt ggaaccaacg gaagatggcg ttcaatttat tcagctgatt
    20821 actcctgtac gtacaaatta acaatgattt tcaatgttct tgaaaattta attgaaaaga
    20881 aatagaaaaa ataaaatttt aaacagaagg ccctaaaatc tcttttaagg ctttctgttt
    20941 atttttgttt aaatcacctt ttttagatta aatcgtctta tatggaaaaa tatatggata
    21001 aatttgtttt attgcgaaaa aaaaggtata atagagtata cttttaataa tgaaaatgag
    21061 ggatgggcat tgaaacaaca agtcattcta aatacggaat tcatgacgtt gggccaaatg
    21121 ttgaaagaag tcacagttat cggtagtggc ggacaagcaa aatggtattt ggcagaaaac
    21181 actgtgttag tcgatggcga accagaaaat cgtcgtggac gcaaacttta tcccggcatg
    21241 atggttgaag ttccagaagt aggaactttt tttatggtaa aaaaaggaaa cgacgataat
    21301 gaggctgaat aagctgtatt taaaaaatta tcgaaattac gaagagctga acatcgaatt
    21361 ttccaagaac ctcgtcatct ttttaggaga aaatgcgcaa ggaaaaacga atcttttgga
    21421 aagtatctac gtattagcta tgacgcgaag tcatcggaca agtagtgagc aggaattgat
    21481 tggctggact gacgatcagg cgatgattca aggagagatc acaaaaggtt catccactct
    21541 tccattagaa atcttattat ctaaaaaagg ccgaaaaacc aagatcaacc atatcgaaca
    21601 gaaaaagtta agtacttacg tgggacaaat gaatgtcatt ttatttgcac cagaagatct
    21661 ttctttagta aaaggcagcc cgcagaccag gcggaagttt ttagatatgg aattaggcca
    21721 gatcaatcca atctatcttt atgatcttgt ccaataccaa gcaattttga aacaaagaaa
    21781 ccagtacttg aagcaattga atgaaaaaaa acaaactgat ttgctttatt tggatatttt
    21841 gtccgaacaa ctagcagcgt ttggcagcaa agtattgaaa gcaagagcac agttcgtcaa
    21901 gcgattggag ttttgggcta attctttgca tcagcaaatc acccatcaaa aagagcagct
    21961 ggaaatcgag tatctcaccg cagtcgattc tttagaaaca catacgcaag agcaaatcca
    22021 agaacaattt ctcgcacttt tgaaccaaaa taaaaagaaa gacctttttc ggggaacaac
    22081 gacagttggt cctcatcgtg acgatctttc cttttttatt aatcagaaaa atgtgcagac
    22141 ttatggatcg caaggacagc aaagaacaac tgcactaagt gtcaaattag cagaaatcga
    22201 tttgattaaa gaagagacag gggaatatcc aatccttttg ttagatgatg tgatgagcga
    22261 gctggatgat aatcgtcaac tccatctgct agaaacaatc gaaggaaaag ttcaaacgtt
    22321 cttaacaaca acgacacttg accatgtaaa aaataaaatg actgttgaac ctgagatttt
    22381 ttatgttcaa caagggaaac taaaaggaga agaaactgaa tgacagaaga aagaagttta
    22441 gtagaacgcg ctaaagagta tgatgccagt cagattcaag tacttgaagg acttgaagcc
    22501 gttcgtaaac gacctggcat gtatatcggt tcgactagtt ctgagggtct gcatcacctt
    22561 gtttgggaaa ttgtcgataa ttcgatcgat gaagtattag caggttttgc aacgaaaatc
    22621 catgtgatta ttgaaaaaga caacagtatc accgttattg acgacggtcg ggggatacct
    22681 gtagatatcc aggcaaaaac tggacgtcct gcagttgaaa cggtctttac tgttttacat
    22741 gctggaggaa aattcggcgg tggtgggtac aaagtttctg gtggacttca cggagtagga
    22801 tcttctgttg ttaacgcgct ttctacacag cttgatgtca aagtatacaa agaaggaaat
    22861 gtgtactatc aagaatatcg tcgtggagct gtagtggacg acttaaagat tatcgaacaa
    22921 acggatcgcc atggaacaac ggttcacttt acgccagacc ctgaaatttt tacagagaca
    22981 actgagtttg atttttcaaa attggctacc cggatccgtg aacttgcttt cttgaaccgc
    23041 gggatgcgta tatcgattga agacaaacga gaagaagaac cagtcatcaa tgaataccat
    23101 tatgacggcg ggattaaaag ttatgtcgaa tacttgaatg caaacaaaac cgtgattttt
    23161 ccagaacctg tatatttgga aggtgaacag caagatatcg cagttgaagt ctctatgcaa
    23221 tatacagacg gctaccattc caatatcatg agttttgcca acaatatcca tacgtatgaa
    23281 ggcggaacac atgaatcagg attcaagact gctttaactc gtgtgataaa tgattatgcc
    23341 cgaaaacaaa agctgatgaa agaaaatgac gacaacttga ccggtgaaga cgtgcgagaa
    23401 ggattgacag ctgttatttc tatcaagcat cctgaccctc aattcgaagg acaaacaaaa
    23461 acaaaattgg gcaattccga agtacggaca gtcactgatc ggttatttag cgaacatttc
    23521 atgaaattct tgctggaaaa cccaagtgtg ggccgtcaaa ttgttgaaaa aggattacta
    23581 gcttccagag ctcgtctagc agcgaaacgt gcgcgtgaag taacgagacg taaaggtgct
    23641 ttagagatta gtaatctgcc aggaaaatta gcggactgct ctagcaacga tcctgaaaaa
    23701 tgcgaattgt tcatcgtcga aggagattcg gccggcggat cagctaagca aggtcgtaat
    23761 cgagagtttc aagccatctt gcctattcgt gggaaaatct tgaatgttga aaaagcaagc
    23821 atggacaaga tcttggcaaa tgaagagatc cggtctttat ttactgctat gggtacaggg
    23881 tttggagaag attttgatgt atcgaaagct cgctaccaca aattagttat catgactgat
    23941 gccgatgtcg acggcgcgca tatccgtaca ttgctgctga ctctttttta tcgttacatg
    24001 cgtcctattg ttgaagctgg atacgtctat attgctcagc cacctttata cggggtaaaa
    24061 caagggaaga atattacgta tgtacaacca ggaaaaaatg cagaagaaga gttgaaacaa
    24121 gtcgttgctt cacttcctgc ctcaccaaaa ccaagcgttc agcgttataa aggacttgga
    24181 gaaatggatg atcatcaact atgggaaaca actatggacc caagcaatcg gatgatggcc
    24241 cgcgtcagtg tggacgatgc tattgcagca gatcagatat ttgaaatgtt gatgggggat
    24301 cgagtagaac cccgtcgtgc attcatcgag gaaaatgcac actatgtgaa gaacttagat
    24361 atttaatcat gaaggaggaa aaagaatgag tgaagaaatc agagaaaaca tccatgatgt
    24421 caatctaacc agcgaaatga aagactcctt catcgattat gcgatgagtg ttattgtcgc
    24481 acgtgcactt cctgatgtca gagatggtct gaaacccgtt catcgccgta ttttatacgg
    24541 catgaacgaa ttaggtgtaa caccggataa agcccataaa aaatctgcca gaatcgtcgg
    24601 agatgtcatg ggtaaatacc atcctcatgg agactatgcg atctatgagt caatggtacg
    24661 gatggcacag ccattcagct accgttatat gctagtggat ggtcatggaa actttggttc
    24721 tgttgacggt gacggtgccg ccgctatgcg ttataccgaa gcacggatga gcaaaatcgc
    24781 tacagaaatg ctgcgtgata tcaataagaa cactgttgat ttccaaagca actatgatga
    24841 tacagaaaaa gaaccagttg tactacctgc tcgcttcccg aatcttttag tgaacggaac
    24901 aacggggatc gccgtaggta tggccacgaa tatcccacct cataacttgt ctgaggtagt
    24961 agcggctatc gatttgctga tggataatcc tgatgtgacg accaatgaat tgatggaagt
    25021 attacctgga ccagattttc caacaggtgg tttggttatg ggaaaatcag gaatccgaag
    25081 agcgtatgaa acaggtaagg gttctattac cgtacgtgca aaagttgaga ttactgagat
    25141 gccaaatggt aaagaacgga tcatcgtgac agaattgcct tatatggtca ataaagcaaa
    25201 attgatcgaa cggatttctg aactgcacag agacaagcgt atcgaaggga tcacagattt
    25261 gcgggacgaa tcttcccgtg aaggtatgcg gatcgtcatt gacatccgtc gtgacgccag
    25321 cgcatctgtt atcttgaata acttatataa attgacatcc ttgcaaaatt catttggatt
    25381 caatatgttg gcgatcgaaa aaggtgtgcc gaaagttttg agcttgaaac aaattcttga
    25441 aaactatatc gaacatcagc gcgaagtcat cacaagacgg acagtctttg aaaaagaaaa
    25501 agcagaagca agggcacaca ttttagaagg tttgcgtatt gctttggatc atatcgatga
    25561 aatcattgcg attatccgcg ggtctaaatc agatgacgaa gcaaaagcga cgatgatcga
    25621 acggttcgat ttatccgatc gccagtctca agctatttta gatatgcgtt tacgccgatt
    25681 gaccggtttg gaacgggaaa aaatcgaaaa tgaataccaa gaactcttaa aactgattga
    25741 agatttaact gacattctgg caagaccaga acgtgttaca gaaatcatca agaatgaatt
    25801 agcagacttg aatcaacgat ttggtgataa acgacgcaca gaattactag tcggtgaggt
    25861 cttaagtctg gaagatgaag atttaatcga agaagaagaa atcgttatta cattgacaaa
    25921 caatggttac atcaaacgtt tggcaaataa tgaattcaga gctcaacgaa ggggtggacg
    25981 tggtgtccaa ggaatgggta tccacaatga cgacttcgtc aaaaatctgg tttcttgttc
    26041 tacccatgat acattgttat tctttacgaa taacggaaaa gtgtatcggg caaaaggata
    26101 cgaaattcca gaatacgggc gcacagccaa aggaatacca attatcaatt tactaggtat
    26161 cgattcgagt gaaagcatcc aggcaatcat tgcggtgacg ggagaagcag aagaaggcca
    26221 ctatctcttc tttacgacgc gtcaaggtac agtaaaacgt acttctgtca ctgcttttgc
    26281 taacatccga agtaatggtc tgatcgcaat tggtttgaaa gaagacgatg agctcgtcaa
    26341 tgtgctactg acagatggtc aatctaatat cattattgga acacataacg gctactctgt
    26401 cactttcaaa gaagaagcag tccgcgatat gggacgtaca gcttccgggg ttagaggaat
    26461 acgcctgcgt gaggaagatt atgtcgttgg ggcagcctta atgaaggaag atcaagaagt
    26521 attagtgatc acagaaaaag gttacggaaa acggacaaaa gtatcggaat atccagtgaa
    26581 aggccgcgga ggtaaaggga tcaaaacggc gaacatcact gaaaaaaatg gtccactagc
    26641 tggattgacc actgtttctg gagatgaaga catcatgctg attacagata aaggtgtcat
    26701 tatccgtttc aacgtatcga ctgtttctca aactggacgt tcaacattag gcgtacgttt
    26761 gatgaagatg gaagctgata cgaaagttgt cacgatggca gcagtcgaac cagaagctgc
    26821 agaacaaaca gttgaagaac aaggatcaga agaatagcca tcaagactaa ttgtgtaagc
    26881 tagcaagaat gaccgattaa aaaatctggt tattcctgct ggcttttttg attagttgaa
    26941 tttctcttaa aatattcgaa actgttcatt ctgtattgct tttgaccaaa atagagtgta
    27001 taatcagagc ttgtgagtag tctaattaat tagataactc tccttgctct taggaaccta
    27061 agagccgaaa gtccacaggg aggtgaatat caatggaaaa cacgaaatat gaaatcatgt
    27121 acattattcg tccaaacatt gatgaagaag caaaaactgc tttaatcgaa cgtttcgatg
    27181 caatcttgaa agataacgga gcagaagtta tcgaatcaaa agattgggaa aaacgccgtt
    27241 tcgcttatga aatgaacggt taccgtgaag gtatctatca catcgttaaa gtatcttctc
    27301 catcatcagc aaatgctgtc aatgaatttg accgtcttgc taaaatcaac gacgatatca
    27361 ttcgtcacat gattgttaaa gaagaagctt aattgttgtt tcatgtgaaa caatagaaaa
    27421 cgatgagagg agatgactat tttgattaat aatgttgtat tagttggacg tctgacgaaa
    27481 gatccagatt tgcgttacac agcaagtggt acggcagtcg caacatttac tttggctgtg
    27541 aatcgtaatt ttacaaacca aagcggcaat cgcgaggctg attttatcaa ctgtgtgatt
    27601 tggcgcaaat cagcagaaac tttagcaaac tatgctcgta aaggaacact tttaggtgtt
    27661 actggacgta tccaaactcg ttcttatgat aatcagcaag gacaacgtgt atacgtgaca
    27721 gaagtagtag ctgacaactt ccaattgctg gaaagtcgtt ctgcatctga aaatcgccaa
    27781 caaagcggcg gattccaaag ttctggtcaa tcagctggcg gatttggcgg aaacaataac
    27841 tctaatcaaa catctcaatc atccaacggt atgcctgatt tcgaccgtga tacttctgac
    27901 ccattcggct caagttcaac gatcgacatt tcagacgatg atttaccatt ctaaacgaat
    27961 ttgataggag ggaaatagaa tggcacaaca aagaagaggc ggacgtaaac gtcgtaaagt
    28021 agactacatt gctgctaacc atattgaata tatcgattat aaagatatcg aattactaaa
    28081 aagatttatt tcagaacgcg gtaaaatctt gccacgtcgt gtaactggta caggcgctaa
    28141 aaaccaacgt aaaattactg ttgcaatcaa acgcgctcgt atcatgggct tgctaccttt
    28201 cgttagcgaa gactaataaa tcctaggaat tgaatgactg atccttttga tcagctattc
    28261 aattcctttt tttctgtaaa aataacctct attcgtttag tcgctcgaat gacgaaagtt
    28321 atggtaaaat caaattagtc atatatggga ggaaaattat ggaaaataaa aacaatcatt
    28381 tatccccgaa acctctcttc cttatcctgt ttatattaat cgaagtattg gtagtcttaa
    28441 ttttaccatt tcgttttgtt agcgcttcgg tcattctatt gatgaattta tggggtgttc
    28501 gctattggtt gaaaatgaaa cgttggctta ttttaaataa acgtgaaaaa atccagcagg
    28561 cttcgactgt agctgaaacc aatctagctt atgtctcaga agtcatgcct gtaggagtga
    28621 ttgcttatca gccatcaagc caaaaaatcg aatggctcaa tccattagca ttgaaaatca
    28681 aagatcaaag tggattaaca gaggaagaat tgctagatac tttttttact gcaaaagaaa
    28741 aaaagaaaaa ccaagtctat ctagcagata aaacatttca gtttgatatg gatacagtaa
    28801 agggtgttgt ttattttaat gatattaccc aaaaccagtt gttaaaactc catcagacga
    28861 acagtcagcc ggtgattggt attttatcta ttgataacta tgcagatgcc attgataaat
    28921 tggatgacaa agagatttct tatttgaact ctttcgtcac tacactagtt tctgactgga
    28981 tgaatgaata ccatgtcttt ttcaaaagaa tcaacgcaga acggtttttc ttcgtagcac
    29041 agatgatcga tctgaaaaag atgatggata aaaaatttga tttgctggat cgctttcgag
    29101 cagaagctga aaaacagagc tcgcctatca cccttagtat ggggattgct tatggctcaa
    29161 gaaccctcga tgaaatcggt ggagaagctc agaataattt agatgttgct ttagtccgtg
    29221 gaggcgacca agttgtcgtg aaagaggtaa aagaaggagc aaaacctgtt tattatgggg
    29281 ggaaatctgc taagaatgtc aaacgcacgc gtgttcgttc tcgagcgatg agtaccgctt
    29341 tgcgtcggat ttttgatgaa acaggcgatg tgtttatcat ggggcacaag tttccggata
    29401 tggatgcttt aggctctgct tttggtgtca gttgtctggc acgcttcaac cagaaaaaag
    29461 cttacatcgt tatcaacgag aacgagatca ttccagatgt agaacggtgt cttgaagaaa
    29521 tccataagca tcctgaatta gaaatgcaac taatctctcc agaacgtgcc atagagctga
    29581 aaaaagaaga ggacctcctc gtgatggtgg attaccataa accttctcta tcgatctctc
    29641 agggcctata tgagcaattt gataagattg tgatcattga tcaccatcgt cgtggggaag
    29701 agtttccaag taaacctctg ctgacttata tcgaatcttc agcttcttca gcttcagagc
    29761 tagtttctga gctgatccaa taccaaagca gcaaaacaaa tcgcttagat cgttttgagg
    29821 ccacattatt gcttgcaggg atggttgtag atacaaatag tttcaatgtc cgtacaactg
    29881 cacgaacttt tgacgttgcc agctatttaa ggtcttgtgg agcagacgca tccttagtac
    29941 aatatttatt gagctcggat ttagcgacat acttggagat cagcaatttg attgctggaa
    30001 gcgactatgt gacttctgat attgttgtgg cggcagggac agacgaaaaa gagtataata
    30061 gtgttatagc agcaaaaaca gcagatacat tgctttcgat gatcaatatc aatgcagctt
    30121 tcgtcattac aaagcggaca gacggcttga ttgggatcag tgccagaagt accggcacga
    30181 tcaacgtcca aatcatcatg gaatccttag gtggcggagg acacttcaca aacgcagcta
    30241 ctcaactgga aaatacgaca gttgaggaaa caaaacagaa gctatttgct gcaatcaaag
    30301 aaaatatgaa tcaaatatat gataaggagt aatccaaatg aaagtaattt ttttacaaga
    30361 tgtaaaagga aaaggtaaaa aaggggacat caaagaagtt ccagcaggtt atgcacaaaa
    30421 ttatctaatc aaaaataact tggcaaaaga agcaacgaaa agcagtatca gtcagttagc
    30481 aggacaaaag aaagcacaag aaaaacacga agctgaaatc ttggaagaag ctaaaaagtt
    30541 aaaagaattc ttggaaaaag aagatactgt agtcgaattg aaggcgaaag caggggaaga
    30601 cagccgtttg tttggttcga tcccttcaaa acaaattgct gaagggttaa acaaacaata
    30661 caaaatcaaa ttagataaac gaaaaatcga attagaaaat ccgatccgtt cactaggcta
    30721 cacaaacgta cctgttaagc ttcatcatga ggtgacggct acgatcaaag ttcatgtcgt
    30781 acaagaataa caaatcttga tagcgatgtt cagctggtaa gtataaccag aaggaaaaaa
    30841 gacaaaccga aatttatctg agaaaacagc tgcagcaatg aaagcaaaag ctgcaaatcg
    30901 atttcagatt gatttcggtt tcttttttgg gaacagcaaa atagcataaa gaaaacgagt
    30961 ataataaaag agaactattt ttttattaca ctttcggtac gaatgatgac ttttctctca
    31021 ttttcttgta aaatgaagca attgaagaca aggagcgata cgtatgaatg aagtgtggca
    31081 ggatcgaatc ccaccgcaaa atattgaagc tgaacaagcg gttttaggct ctgtttttct
    31141 tgacgcagaa acgatcattg atgccatgga gtacatagag ccaaaagact tttatcgtcg
    31201 tggccatcaa attatttttg agacaatgat cgagttaaat gatcgtaatg aagcgattga
    31261 cgtggttact gtcaaagacc ggctggaaca agccaatttg ttagaagatg ccggtggttt
    31321 aagttatctc tcagacttgg cattagcagt tccgacagca gcaaatatcg tctactatgc
    31381 gaaaatcgtt gaagaaaaat cattgctgcg tacattgatc cagacagcaa caggaatcgt
    31441 tacgaaagga ttcgagcaag gagaagaagt tcaaacaatt ttagatgatg ccgaacgcag
    31501 tatcttggag gtttcggaaa aaagaaatcg aagcggcttt ttatctattg ctgaagtact
    31561 gaactccacg attgaaaata tcgatcgact agctcaaaac aatgaagaaa tcacaggtct
    31621 accaactggc tatcaaggtc tggataaaat gacagcaggt ttccagcccg aagaactaat
    31681 cattcttgct gcacgtccag cggtaggtaa aacagcgttt gcattgaata ttgctcaaaa
    31741 tgtaggaaca aaaacagatc gttctgttgc gatatttagt ttggaaatgg gggcagaatc
    31801 tcttgtaaat cggatgcttt gtgcagaagg ttcgattgag gccagccatt tacgtacagg
    31861 tcagctttcg gaagaagaat ggtcgaatct gatcgttgcg atggggagtc tttctcgagc
    31921 aaatattttt atcgatgata caccagggat caaaatctct gaaatccgtg cgaaatgtcg
    31981 gaaactagcg caagaaaaag gcaatctagg cttgatattg atcgattatt tgcagttgat
    32041 tgaaggtaac ggtaaagaga accgtcaaca agaagtatca gatatctctc gccaactgaa
    32101 aaaactggcg aaagagctga aagtacctgt cattgctctt tcacagttat ctcgtggagt
    32161 agaacagcga caagacaaac gaccagtgct aagtgatatt cgtgaatccg gatcaattga
    32221 acaagatgcg gacatcgtag ccttcttgta tcgagatgat tattatgaaa gagaaggcgg
    32281 agatgacgat gatggaaacg agccaaaaaa tgacaacgtc atcgaagtca tcatcgagaa
    32341 gaaccgaagc ggtgcacgag gaacagttga actactgttt atcaaagaat acaataagtt
    32401 ttcgtcgctt tcgccaagag aagaatttta aagaagaggt tgtgagcctt gagcaatccc
    32461 gagagctctc gtaagaagat gcaaggagta accgcaggaa cgactagagt acttaattta
    32521 aacagatctc caaagggatt gtgacaaaag tcttgtcaca gtcccttttt ccgaataaac
    32581 ggtgttcaat cagctgaccc ttggtattag ctcagcaaac gtcaaaatat gaggaactat
    32641 tttgacgttt gtttctctaa tactcaggtc aaaacgctga tcttacgacc tcttttcctt
    32701 aaacggtgtt ctcctgccaa ctcctcggtc acaagtcaca atatcatcaa acatgagaag
    32761 cagttttttg aaattgctcc ttgtgactca gagttaaacg gcaggctcac aacctctttc
    32821 ttaaacggtg ttcaaaagct tgcatctgcg gtaatacgcc caatcaaacg aaaaatatga
    32881 gaagctattt ttgtttggct gttcttatta cttgatgcag gacagctttt tcacaacctc
    32941 tgattcacgg tgttccaaaa gtagcttctt cgaaaaataa gtcgaaattt cacaaaaatt
    33001 tgagaagcaa ttttcgtaca ttccttctta tttcttgaag ctgaccactt ctgttacaac
    33061 ctctttttta ataaccattc taaaaagata aagttcgttt tttaagcgtt tttataaaat
    33121 aaaaataaaa atcattcgat tttatttgaa atatgtatct attattgata caatggttca
    33181 ggattaaata atatagaacg aggtgttcac atgtcatctg tagtagtagt aggtacgcaa
    33241 tggggcgatg aagggaaagg aaaaatcaca gactttctca gtgaaaatgc tgaagtgatt
    33301 gcacggtacc aaggtggcga caatgcaggg cacacaatta agtttaacgg tgtgacttat
    33361 aaactgcatt tgattccttc tgggattttt tataaagaca agatcagtgt gatcggaaac
    33421 ggcgttgtag tcaatcctaa atcattggtt aaagaattag cttatttaca tgaaaaaggt
    33481 gtagaaacaa gtaatttgcg tatttctgac cgcgcgcacg taatcttgcc ttatcatatc
    33541 aaattggacc aattacaaga agatgctaag ggcgaaaata agattggtac aacgattaaa
    33601 ggaatcggac ctgcctatat ggataaagca gctcgtgtag gtatccgtat tgcagactta
    33661 ttagataaag aaatttttga agaacgtctt cgtttgaatc tagatgacaa aaaccgtcaa
    33721 tttgtaaaaa tgtttgattc agaaccactt gattttgacg atatttttga agaatattat
    33781 gaatacggac aacaaatcaa acaatacgtc acagatactt ccgttatctt gaatgatgct
    33841 ttggatgcag gcaaacgcgt gttgtttgaa ggcgcacaag gtgtaatgct ggatatcgac
    33901 cagggaactt atccttttgt tacttcttct aacccagtag ccggtggggt aacaatcgga
    33961 agcggtgtag ggccttcaaa aatcaataaa gttgtcggcg tctgcaaagc ctatacgtca
    34021 cgtgtcggtg atggaccatt tccaactgaa ttatttgatg aaacaggaga acaaatccgc
    34081 gaagtaggac gagaatacgg tacgacaact ggtcgtccgc gtcgtgtagg ctggtttgat
    34141 tctgtagtta tgcgccattc taaacgagtt tcaggtatta ccaacctatc tttaaactcg
    34201 atcgatgtat taagtggatt ggaaacagta aaaatttgta cggcttatga attagatggc
    34261 gaactaatct accactatcc agcaagcttg aaagagttga accgctgcaa accaatctat
    34321 gaagaattgc caggctggtc agaagacatt acaggatgca aaacacttgc agaactgcca
    34381 gaaaacgcac gtaactatgt acgtcgtatc tcagagcttg ttggtgtacg tatctcaaca
    34441 ttttctgtcg gacctgatag aacacaaaca aacatcttag aaagcgtctg ggcgcaaatc
    34501 taaggataaa aacgacgact gaatcaggac gttcttacca gagcgagtcg aagtgtttat
    34561 ctatacgata ataataactt gaacactgtt tattcagaat aagggactgt gacaaaaacc
    34621 gtgtcacagt ccctttttcc gaacaaacgg tgttcaaaag cttgcatcta cggcactaag
    34681 cccaatcaga tgaaaaatat ggagtgctat ttttatctga ttgttcttac tgcttgatgc
    34741 agagcagctt tttcacaacc tctccactaa acggtgttct cctgccaact cctcggtcac
    34801 aagtcacaat attcaacaaa catgagaagc tgttttttga aattgttcct tgtgactcgg
    34861 agctaaacgg caggctcaca acctcttggt aaacggtgtt caatcagctg accctcggta
    34921 ttagctcaaa aaacggcaaa atatgaggaa ctattttttc cgtttttttc tctaatactc
    34981 aggtcaaaac gctgatttca caacctctga ttcacggtgt tccagaagta gcttctacgg
    35041 aaataagccg aaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc
    35101 ttgaagctga ccacttctgt cacaacctct tattttgatt agaacttgcg aaaataaacc
    35161 ggttaaagtg tgtctagcgc aagagatttg ctataataga cgataagggt aaaatgtaac
    35221 gagaaggggt tgaaaaatgt gtatcaaatt gtaacagatt cttgttgtga tctgccatac
    35281 catgtattag caaaagaaaa agttgatttt ttatcaatga atctccaatt gaatgatcaa
    35341 gagttagtag atgacctcgg aaagacattc aattatgacc gctacatgaa tcagctgaaa
    35401 aatggtgcga tgcctacgac atcacaaatc aatgttggcc gatatttaga atttttccgt
    35461 tcttatgcgg aaaaacagat tcctgtttta tatgtggctt tttccagtgg attaagcggc
    35521 tcttacagta gtgcgcttca agcggttgaa ttgctgaagg aagaatatga agaccctgag
    35581 atctatgttt ttgatacaaa agctgcaagt attggggaag ggcttttagt attggaagct
    35641 gtaagattga aaaaagaagg taaaagcatc gaagaaaccc tagagtggct ggaaagtaat
    35701 tatttgaaag tccattcatg ggtaacagta gacgatctga aatatctaga acgaggcggt
    35761 aggatttcca aagcaagtgc tactcttggc agtctattga gtgtaaagcc tattattacg
    35821 gtggataaag aaggaaggct gacgaatgtt gacaaagttc gaggaagaaa caagtcgatc
    35881 cagacaatcg tcaatgagac ggtaaaaaca atcgttgcac cacttgatca aatcgtttat
    35941 gtggcttacg ctggggatct agagagcgcg gagaaggcaa aacggctttt ggaagagcag
    36001 ataaagatga aagatgtgaa gctttatccc ttaggaccaa cgatcgccag tcacacaggc
    36061 tatggctgta tcgcgatttt ttcgatggga atcagtcgat aaaagcagta actcattctg
    36121 taaaaaagcc cagaaattga ttgtaacaaa aacagcgact cttaaaagat agatgagcat
    36181 cctatctctt agaggtcgct gtttttttat tttttaagct aaataggcca ttatgcccat
    36241 aactcgttca attgtttttg aatatctgca ttttccaaaa attcatcata tgtcgtatca
    36301 gctcgatcga tcacaccttt atccgaaacg gcaatgatgc ggtttgccaa tgtttggata
    36361 aattgatggt catgtgacgc aaataagatt gagccagtaa atgccatcaa gccgtcattc
    36421 aatgctgtga ttgattctaa gtctaaatgg ttcgttggat catctaatac aagtacgtta
    36481 gctttcgaaa gcatcatttt tgaaagcatg caacggactt tctctccacc agataaaaca
    36541 ttcactggtt tcaatacttc ttcaccagaa aacaacattc ttcctaagaa gcttcttaag
    36601 aaggtgttat catcttcttc tttacttgca tattgacgca accagtctaa aatcgttaga
    36661 tcagtatcga attctttcgt tgtatccttt ggtaaataag aattacttgt tgtcacaccc
    36721 caacgtactg ttccagtatc tggcgtaatt tcacccatga taactttgaa tagcgttgtt
    36781 gttgttatat cattttctgc gacgaaagcg accttgtctt ctttgctcaa attaaaagat
    36841 atatcatcta aaattttctt tccatcaatc gttacactta cattttctac ctgcaataag
    36901 tcgtttccaa tctcacgttc aggtttgaat ccaacgaatg gataacgtct agaagaaggt
    36961 tggatatcgt ctaaagtaat tttttcaagc atttttttac gtgaagttgc ttgttttgat
    37021 tttgatgcat tcgcactaaa gcgggcaata aattcttgga gttctttgat ttgttcttct
    37081 tttttggcat ttgcgtttgc ttgaagttta gccgctagtt gactagattc caaccaaaaa
    37141 tcataatttc ctacataaag tttgatttta ccaaaatcta gatccgccat atgtgtacat
    37201 actttgttca aaaagtgacg gtcatgggat acaacgatca cagtattttc aaaattgatc
    37261 aaaaattctt ccagccaatt gatcgattgg atatccagac cgtttgttgg ttcgtctagc
    37321 aaaagaacat caggtttacc aaatagtgtt tgtgctaata acacttttac cttttgtcca
    37381 ccagttaatt cactcatttg ctgatggtgc aattcttcag ggatgttcag accttgcagt
    37441 aaaacagctg cttctggttc agcttcccat ccattaagct cagcaaattc tccttctaat
    37501 tcagctgctc gaataccatc ttcgtcagtg aaatcctctt tcatgtaaat cgcatctttt
    37561 tctttcagca cttcatacag acgcttgtgt cccatgatga ctgtttcaag tacagtatag
    37621 tcttcatagt cgtaatggtt ctgtttcaat acggccatcc gttcatctgg tcccatagta
    37681 acggaacctg tggaaggctg cagatcccct gataacactt taaggaacgt tgatttacct
    37741 gcaccatttg caccaatcaa gccatagcag tttccggggg taaatttaat attcacatca
    37801 tcaaatagtt tgcggtctga aaagtgcaaa ctcacatcat ttacagtaat caattttttt
    37861 cctcactttt atcattatta gttttgacaa gtcttataga attatatagg ggaaaggtaa
    37921 aagattcaag gcaatcgaac attctttgtg tttcacgtga aacagaatga aaaaaataaa
    37981 aataaaagcg gagcgaaaat agctactata ggatttatta gtttgcaaca gcataatttt
    38041 tgacgttatt tataagaggg agtactataa aactgtaaaa gaaatgaaag aaggattgaa
    38101 aatggatgaa aaaagaacca tcgactgggg ctcattgatt ttgggaattt tatttgtact
    38161 tgtctcattg ttatcatttc aagaccctgt cggaaattta gttgcaattg tagtagtctt
    38221 tgcgattttt gcctttatta aagggatatt tgaactgttt gtacggaaca gattaaaaga
    38281 gctaacagga tataaaggaa agatgccctt aataatcggg atcatcgata ttctagttgg
    38341 cgtctttttc ttattcaata ttggtgcagg agtcgcagca ttgccttttg tttttgcagt
    38401 atggtttatt gctgattcag ttttagcgtt atttactgct gacttggcaa gaggagtaag
    38461 tgaaggatat tattggttta cgatcatcgt caatatttta ggaattttat taggaatttt
    38521 cttattgttt aatccaattt cttctgcgtt gacattaagc tttttagttg gattctattt
    38581 tatgttattt ggtatcacac atatcgtcta tgcatttaga taagtaaaat caaacaaata
    38641 aaaaagccgg cttccgatta cagttttact gttgtaattg gaagccggct tttttatcat
    38701 ggacaaatat gcacgaggtg atttttaggt gtcgagacaa atttatgcaa aaatgtgaga
    38761 agctatatac acaaatttta tcttaatact cgaagcatag cgcagttgtc acaacctctt
    38821 ttcatataat tcattcaata ctggcaaatc atggacttca tatttttctt tgaatgcttg
    38881 gatttcttct tcagaatatt ttcttggatc taaatgcaga tcttctactg gcaatgggcg
    38941 cttgttattg atcttcacat cgattactac aggacgatct gattttgcag ctgcatcaaa
    39001 ggcaaatcga agttgcgagt attctgtgac tgtaaagcta tttgccccga gcgcttctcc
    39061 aactttaccg aaatctgcat cttctaaaaa tacaccaaat ttcttttgtt ccgtatcttc
    39121 ttgttctgct tcgatgaaac caaaagaatc attcgaaaag acaacattaa taattggaag
    39181 ctgatatttg acttgtgtaa tgatatcttg catgaccata gcaaacccgc catcaccact
    39241 taaggtaaat acttgttttt ctgggtagct tagttgtgcg gcaattcctc ctggcacacc
    39301 attacccata gttgcgaacc atccagatgt cgtatgtttt tgtttaccgt tcatattcaa
    39361 taaacgaata gaatggatag tcgtgttacc gacatctgtg acgaaaatcg catcgtcttc
    39421 agcaatacga ttgatttctt tatagacagc ctctggacga atcggttctt cctctcgatc
    39481 ttcaaaagat ttcaaccaat ttacccattt ttctttattt tcttgatttg ctaggtacca
    39541 gctatcagca gggcgagcat cccctaactc gacaagtctt tgcaaagctg tgtttgcatc
    39601 accgaggatc gacaaagatg tttcatggcg tcgtccaaat tttgacgcat cgatatcgat
    39661 ttggataaat tcagcagttg gattaaaaaa tgcacgtcca aatgggaagt cgctaccgac
    39721 aaataagatc agatcggctt ctgccaatgc ttcatttccg ggtttagtag cgacacgtcc
    39781 agcaaaacca agaaagtttt cataatcatc aggaataatt ccttttgcta gaacggaagc
    39841 gacaacagga actgaaaaat gttctgagaa ttctttgatt tgcggaaatc cgtttcgcgt
    39901 tccttgacca acataaagaa ctggtttttt tgctttttca agataaggca aagcagctag
    39961 caaatctttt tcttctggta atatcacact tgttttgtga gtgtgagcgg tggagaaagg
    40021 ttgttcgtca atttcttcaa aaccaagatc aacagggata gtcacgatag ccacgccttt
    40081 atgctcatag gcggctttaa tggcttcatc tactacatgc ggaagacttt gtggtgtcat
    40141 gactgtacga ttgtatacgc taacatctgc gaaaatagga ttttcattta gttcctggaa
    40201 agagttatag ttcatggatg tagaagcaac ttgtcctaag aacgctacta gaggcacatg
    40261 gtccatctgt gcatcataca aaccattgat caaatgtgtc gcaccaggtc ctgcagagcc
    40321 gaagacagcg ccgactttcc ccgttaattt tgcatctgca gcggctgcga gtgcgccgac
    40381 ttcttcatga cgaacttgaa tgtagttgat ttcggttttt tcttgatata gcgcatccat
    40441 aattgaattg aaagatcctc cgggaatgcc gtaaatatgg tcgatacccc agctttcaag
    40501 aacttttacc attgcgattc ctgcattgat ttttgacatg gtgtttcact cctttagcaa
    40561 tgatgataca taaatttttt gtatctagag tatagaactt tttatcgaaa atcccaacta
    40621 attcgtcttt tcacaaaaat gtagtcatgt ttttgggaat atgctagagt agtacataga
    40681 tagattcaag agaggggaat ggcatggttg aatggctatt gagacttgaa ccttggcagc
    40741 aagcacttgc tgggacagct tttacttatt ttatgacagc tcttggtgcc gggttggttt
    40801 ttttctttaa agaaatcaaa aaagaagtgc taaacttgat gttaggattt gcttctggtg
    40861 tcatgattgc tgcaagtttt tggtctttgt tagatccggc tattacaaaa gcagaagaaa
    40921 atggagatat tgcttggcta gttgtaagta ttgggtttgg tttaggcggt gtgtttttat
    40981 atatggcaga taaaacactg ccccatatgc attttggacc acaacatgaa gcagaaggat
    41041 tgcctaccca tttaaaacgg acgatcttgc ttgttttttc tattacattg cataacattc
    41101 ctgaaggttt agccgtgggg gtagcattcg gtgcagcagc aactgcggat aatccgacag
    41161 ccgctatatt agccgctgtt tcggtggcgc taggtattgg tatccaaaac ttcccagaag
    41221 gagcagctgt atcaatcccg ttgcgacaag aaggtctgag tcgtaaaaag gcctttgttt
    41281 acggacaagc ttctggaatc gttgaaccaa ttgctggagt gattggagcg ctactagtaa
    41341 cgaaagtgga gctgctgctt ccttatgcac ttgcttttgc cgcaggagca atgatttatg
    41401 tcgtggtgga agaattgatc cctgaagcac agcagacatt gtccagcaaa cgtcattttg
    41461 cagtttttgg cgtcatgagt ggatttatca ttatgatgat tttggatgtg gcattaggat
    41521 aaataaaaaa aatatatatg atatatcaaa tagggccgcg aacttatatc gcgaccctat
    41581 ttttttagta agttatatca taatgaagtg aatggtatca tacattaata atagtttttt
    41641 ctatgtgtat ttcctttgat ccagcgaaca agccagatga taagtgcgat tgggattaga
    41701 actttgaccg caaaccataa aagcccgctt aggacactga caaaaagact gatgacgaag
    41761 ctagctgcaa ttagcactaa aagaaccatg aagatattta agaacatatt tttttgacgc
    41821 atacaaaacc ctcctcttgt tcattcttta ctatagaaaa agtataacag ggattgttta
    41881 aaaacacctc caactgaaga ctgattttta cttcatctac ttaaatgatc aaacaattgc
    41941 tttttctctg gtttatcatc taaaatagag cggaaaagga ggagaatatc atgcctaaaa
    42001 atcgtcttga agcatttaca gatgctgtaa tcgcgattat catgactatt ttagttttag
    42061 aacttcatga acctaacgga gacacgtggg aggcgctcgc tgcattaggt taccgatttt
    42121 ttatctatat tgtcagtttt atcattttag cgatttattg gaacaatcat catcatttat
    42181 ttcaagttgt acataagata aatggacggg tcttatgggc gaacagtttc tttgtttttg
    42241 cgctttcgct ttttccgttt gcaacttcat ggatcagtga gtacatcaat agcctggctc
    42301 cagaaatgac ttatggtttt gttaccttga ccgctaatat tgcgtattat atcttggcaa
    42361 aagaacttgt caaagcaaat aaaggccacg agaaagcatt gaaggcgatg ttgaataatt
    42421 acaagaaatc gtatctatcg attggtttga atgtgttagg aattgtctta gggtatttag
    42481 tagcgccagt agccgtgctg atcgcaaaca tcgtgattct agctgcttgg atcatcccaa
    42541 gtcgtaccat cgaatcacaa tatcggtaaa atgatccgtg tttaaaattt aagagaaaaa
    42601 tatagaaaaa ataaataaac gatcaaatat ccgagtgata ctagtattca aagagggatg
    42661 cagatggatc aaaaaagaat tcatgtagga ctgattacta gttttgtcac gatgcttatt
    42721 tatttggatc aaggtcattt gacttggaca gtagttggtg tcgtaggatt tttgacatta
    42781 ttcacagcaa taaaaaaata aacatcttta tgtaatctga tgttctatct atttaagaaa
    42841 agcatgttta cagcagtatg attctgttgt aaacgtgttt ttatttgtgg aaaatttaat
    42901 ttttagaaaa gtgtatcgaa aaatagatag ttagtttttc cacagtggat aacttcgtaa
    42961 gagataaaaa taaaaaatta gtcaaagaag ggcgtataga tttcttttga taggagatat
    43021 acaacagaaa tgaataaata ttaacgtgtt ttcaaacagt ataaaacggt gtggtttttg
    43081 gaataaaaaa ataacatatc tcattttacg cttttgttat tttatactta aaaaataacg
    43141 acacagaaaa taccgtgtct cagatttctc tactacttct aaaaactact gtttttttcc
    43201 tttgaaatgc cttcaaaaag taggatcagg cagaatatac tggcagaatc aaggagaagg
    43261 gagcctaaat aaggagaaaa accatagaaa atataaagta attacttata aaacaagctt
    43321 tttatagaaa aataatatac ctgagtaggg tataaattaa gacggaattc ctttctagat
    43381 tgagatattg actaggaaga atgttaagat tttaagcctt taagctaaaa aaaaaccctt
    43441 tttgttaaat aaggggaata tagcctgtca gtttcaaact gcaagtcgtc ctgctgcaat
    43501 aatatagtag attagagatg aaaatagatt tttttaaacc aatgactgaa taaaaagacc
    43561 gtcatagata cacattggaa tgtgtctatt acggtctttt tttacgaacg attttattga
    43621 agacggacag ttcgggtcaa aaataaaaaa gctacgatca gaaataagaa taaaatgtat
    43681 cccaaaataa tggctagacg gtctaactta tttgtcgata gatgtttgtt tagaagttga
    43741 taggcccata aacctatcag tcctcctgtt gtattagtta tcaaatcagt gatgtccgct
    43801 acgccaatac cgaataggaa ttgaatcaat tctgccaaga agcttacaag gaaaataatc
    43861 cctaattttt tagaaaaaga aagtctcttg aaattgacat tcaaaagcac cccaaaagga
    43921 aaaaagacaa tcaagttata agtggtctca cgtaataccg tcgtattttc aaaagaaaaa
    43981 gtagaaaaag ggacgagatt gacattgctg taagaataag tgagaaattg tggaagatta
    44041 aatgatagct tgaataaaat caaccataat agaaagaata aataaatccc taataaaaat
    44101 tttgatacat accgcataga catctcctcc atttaaaaag tataccatcg aaaaccgctg
    44161 aaaaatcata aaaaagtatg aagtttaagg accaacgtag ttatcgtacg aaaattagaa
    44221 gctttttttt gttgggaatc cggtttcttt aacaaagcta agatagcgag ttgcttggaa
    44281 aagttgctat cttttttctg tcaaaacgac tcggaatgtt cgttttttgt tctaatttct
    44341 ccaagttgtt tactttttga tactaagttt atgaaaaatc aagaaatagt tgttatacta
    44401 ggtaatgctg acaaacggga ttggcatttc atcttggttc agcttttttt ccaattacta
    44461 ggaaggaggg atagattgtt caagacttat tttcgtttca ataaaataca agataatcct
    44521 tttcgtatca tgaatctgat gctacttatc tttattgtat tatggttagg ttacataaat
    44581 catgattttt tgatttcaag tttttcatca ttagggatct ttactttttt ctattatcaa
    44641 aacataccga tgaaatattt gctgaaacgt atgtttctga tcggttgcgg actgttggtt
    44701 gctttcgttt tggggatctt atcgacttat gttttatggc ttgaaccatt tgccgtagct
    44761 ttggttgctt tttccagcag attcgtgttg cgattattcc atatttctaa accaggtggc
    44821 ttgttttttg cgatgctttc tgccatggga acgagcatgc agctgccaat cgctcaatta
    44881 ccgatcgtct cactttattt ttttatgggt gtcgtttttg ccctgattgc ggcagtgatt
    44941 acaaaattac tggattcacg gcctgagcag acaattgaaa aagcaacttt aaaagaaaga
    45001 tttcacgaag agcctttagt gatcattgat tctgttttct acagcgctgc cttatttctt
    45061 tccgtttatg tcagtcacgg cttgaatctg cataatcctt attggttgac cttgtcatgt
    45121 gcatcgattt tgctagcaga aaacttggat gcgatgaagc atcgacaagt ccaatatctg
    45181 attggatcga tgggtgggtt atgtgtgtcg gcattcttgt catttgtgcc gtttacgcag
    45241 ttgcagacca tttttctgat cacttttcta tatggaatcg cacaatttct agttgctaga
    45301 aattatgcag ttgctaatat ttttcttaat ccgatggcgt tgatgctatc tacacttatt
    45361 cgtggagcat acttgatttc tttgatcgaa tatcgttttt tagggatcgt cataggaagt
    45421 ttcatcggtt taggtgttgc gtgggtaatg acggttggtt tgcaacatta tttaacggtt
    45481 gttcgtcaaa aattagaata gaaggacaaa tatatgtgcc aaaagaggtt atgacaagat
    45541 ttttgtcaca acctctaatt caaggtgttc aaaagccaga ttctcagcat taagtcaaat
    45601 tcacacaaaa atgtggaaag gaactttcaa aaaaatttta tatttattct atcaaaaaat
    45661 tttatattta ttctatcaaa aaattttgtt tatgatggta actgaataaa ctttcctgag
    45721 atggtcaatg ctttccttga aagtcttaca gatattcttt cttcatagaa agtttaagtt
    45781 ttatagttag tgtacaataa aagtatgttt ataccatatg gtgtccggat aatcagtcat
    45841 ttaaacaatg aggttcaaag atatgaaaag gggaaatttg atgaagaaaa taagcaatga
    45901 aatccaaatt ctggcagaaa ctttaactct tcccaaagtc gttatagagc aaatgattgt
    45961 acaagcaaaa aacatccttg atgaggtgtt tgagcaatat agtcatgaac taatggatcc
    46021 taataaagca aaggcgactg caaagaaaat agacaaagtc tatgaagagg aaccttttgc
    46081 agcattagct atttatctat atgcagcttc tcaaagttgg aaaaaaattt atcaaccatt
    46141 gaagattcca agaactatct atttggcaac aatgaatgct tttactagat ttattcatga
    46201 acatttccaa gtaacaggaa gctatcgctt tgaccgtggt ttttggattt ggcattacac
    46261 tagtggcttg atctttcgga ttggtgaatt ggagtacgaa atgacatatt ttccgaaagg
    46321 gtacacggat ctaagattag aaggaaagca gtgcctttct cttcatattc cttccgatgc
    46381 agatttatct cagaataaga taagagatag ttacgaaagt gccattcgtt tttttgaact
    46441 ttattttcct gattaccatt accaagtgat gtacacagat acttggttac tatcacccaa
    46501 tcttactaaa tggttgaaaa aagagtcaaa aatctgtctt tttgcagccg attatcgatt
    46561 attatcagtt gatgaacagg acgatagtgg agtcccttgg atctttggac gagtagatgc
    46621 ccaaatacat gattatccag aaagtacgag tttacagcga caagcaaaag agcaattgct
    46681 tgcaggcgag cacattggct ctggcttagg tattcttact tcataagttt agtacttcga
    46741 aatagtttaa aagagcgtga gacaaaagta aagaacactt ttgtctcacg ctctaaacac
    46801 gtataaacgg cggaagcaga agcaactcct tcggaaataa gctgaaattc acaaaaattt
    46861 gaaaagcaat tttcgtgaat ttcttcttat ttcttggagt taaacgcttc tgtcccagcc
    46921 tcttttttag tgttctatcg aacacacagt acgttcaata ggtaaactag ctataacaat
    46981 agatattaaa gttaacggac aagagggcct tttttaggta gctaaaacgt aataatgaaa
    47041 atttatttcc agagatagga gtcaatcagc tagtctgatc gactgtttta acaagttgac
    47101 tttcatttta acttttgata ccatttaaaa cacaaatcgt aattgtttcg atttgtgttt
    47161 tttagcatga ctacaatcaa agaagaaagt gggtcgtcca tatggaaaaa acagatatct
    47221 caagtgcata ccgccgcttg aaaagcccaa atatcaaaac acgaaaacgt gcgctgaaga
    47281 tcatcaaaga tgtgaaacgg aatagtggga aaaggtaaga agaaggaaac ttaattaaaa
    47341 aaatagccga aaaacgtttt tcggctattt tcaataatcg gtttttgtgt aaggtttccg
    47401 aaagaactgc tgttgatttt ccatttttaa catatgataa attggtagaa tctttctttt
    47461 caaattgata ccattcccta attccagtta tatagttaac tacagaacca caaagcacgt
    47521 acgtttataa aagtattatc tgtagttatt tttcaattcc ctttcaacct cttattttga
    47581 ccagtagtat tgatcacttt accttttaac acctttgttc gtttttgaaa catttttagt
    47641 caagaatgga aacgtaacta cataatcaaa ggttttgcga aatatttcat gaaatatttc
    47701 atgtagaagc gagcaatacg gttgcaaata accattatcg tttaataagc agttacgaaa
    47761 gctcccaata tctctaacgt tcagctcact ccatttcttt tcttcaaaaa aatcagtgat
    47821 tcgtatctct ttctatttgt cgaaaaagtt aactttaaaa agtaacgccg aaaaaatatg
    47881 caaaaaaata aaaaagcagt tactattgct agaataacat caaggaataa taagttttgg
    47941 ttttcagata atagtcgata agttgtgtat tggaatttta gatacagtaa taaagtattt
    48001 ttcatgaaat tttgtgagaa tcactattac aagtatcttt aataaaatta atggttaagg
    48061 aggaacttaa agtagaatgt aaatgaatag ttgtagtcag tcgattgtga tactagactc
    48121 aaagttgcag gaataagttt ttcaatttgt gattggaaga taaaaaatga aaaagaaggg
    48181 ctttttttta tactttgttg attgtagtgt ttattttccc tctgtttagc caagtaacat
    48241 tttctatgac tcaaccagtt tcaagtgagg aacatgataa cctttttcgt gctacagaag
    48301 agtttaagaa atatcaggaa aatattgttc cggagactcc attagctagt gagccaatta
    48361 ctgatattga tggaaaccaa ataggatggt atatacagta cgaagttatg gtggtaaata
    48421 atgactcaat agtaaaaaat acagtaggct tagagctaac accgattgaa aaggtgagtt
    48481 cattgttaac gtatatttat actgatgaaa gtgacgagac tgagatcatt ttaacggatt
    48541 actcaaaaat tgctactgat aaaaagtata tattgtggat gtagacacta gtgaaatact
    48601 ttatgatata gaaattgatg aaaatttact agatgtagca caagaaatcg atcatcaaaa
    48661 gcaggaagct attcgatatg ctggtagaaa agggaaaaga aaatatttat tacgtgaatg
    48721 tagcaaaagt tagagaagat gaaaatgagt ggaaagaatt caagagtcgc tactcaatta
    48781 actcgactcc gacatttaca gtttacagag aaggatcgat agaaaaaact gttttttgga
    48841 ctaaagaaag tggaatgtct ttagctgaag tagaagagtt tttggattat gttagtatgc
    48901 aacagtaagg gagttcttat tatgaaaaat tttgacacat attatgttat tgttttttcg
    48961 atatctttgc tgttaatatt actaacttta atgcagtata aagagtatcc agagtatttt
    49021 attttaactt ttgtatattt agtaagtagc tacacacttc tatataaatt cagaagttct
    49081 tctagagttt ctaaagtttg tttcttaatt agcttattga ttctataata tttttgattt
    49141 atataggaaa ttaaaaatat tatagaatca acactcagag aacgggttgg tttttaatag
    49201 atttaataag tactgataat gaaatttctc ctggttggga aaacgaagtt ggttaccctg
    49261 tagaagaatt ttttcaagat tactttgcgg agtatgccga taggataatg agagattacg
    49321 taacagataa aactcaagaa gtcatcaatc aatcccagtc attaaatgaa ttatctgata
    49381 aggcgaaaga agaagcagtt gccattattt cttcagggat tagtgactat attgatatga
    49441 gtggtgaaat caattatggc gataaagaca aaattgtacg catgataaaa gcttttatca
    49501 aaacttttga tgtgaaggca gatcttaagt ttaatgatac ttacctagta ggaaaattaa
    49561 ttaatatcct tgggacagag aaagatacgg aaacgtttat ttcctctttg tctatgttgt
    49621 ttacagataa gcatttttca actcagcttg gtggagagga actagtggaa atcttttaac
    49681 cattacgccc agcattaata aaagtatatc aaaaaagtac tcctgatgat ttttaagatt
    49741 ggtttgagaa ataatgtgaa aacactattt ttaatgttaa ttatagatag agatgaacgc
    49801 gtcatatggt taaaagaatg aaaaagtcaa agatacactg ctatatttca ctaaggatat
    49861 agcagtgtat ctttcatgtc gtttcactgg cagtttttta taaaaggagg tgtgcatttc
    49921 agttgctttt ctttggtagt tagttgaatc gtttaagaat taacggatgt ggcagacagg
    49981 tgctctgtcc aaaaaccagt aaaatctttg atggttccat ctttatttag ctgtgcctgt
    50041 tcaaatactg ttttgttttt accgaatgga tcaattgcaa taattgttcc gatccccgca
    50101 cgtttggcag caagtaatcc tgagtaagca tcttcgataa caagacaatc agccggagct
    50161 aagctcagtt tgtctgccgc tttaagaaaa atatccggtt gcggtttccc agggaaagag
    50221 ccgtcgtcat agacaatctt gtcccagtca aaccagcggg ctaaatcgaa aatatcaaaa
    50281 taaaaagcaa cattctcttt gacagtagcc gtggcaatcg ttaatggaat ctgttggtca
    50341 gtcagctggt caagagtcgc ttcaagccct tttgtcaact gaagctcgtt ttcattttgc
    50401 aagcaaagca tacgataata gctttctttt tcttctgaca atacggcgat ctcagaggcg
    50461 gtcaaatgct ctgaaatgaa atgtttcaaa atctccgtat tcgtccgacc atgaatattt
    50521 tttaaaatat cctcgtctga taaaccatct tttgtatgat catgtatcat atgcagccaa
    50581 gcagcttcat gcagatgaga gtccaaaaac attgttccgt tgaaatcaaa tataatccct
    50641 ttcatagtta cgctcctata gtggtatttt cggttgaatc agcaatttgc agatcgacat
    50701 attgtgcata gtgctcttga acctcccgcg agatctggcg atccgtaatg agcagatcga
    50761 aatcatgcaa attataaaac acataaaaat catctcgatt gaatttttta ttatcaacga
    50821 gtagatattt cttacgggaa ttatttagag cgatctgctg tgcttctcct tcttcggtac
    50881 tgtaagtaga gatcgcttcg ttgtgaacgc catttgaact gataaatgct tttgtaaact
    50941 ttagtcttct taaattgtcg ttggtgatcg gtccgacaaa tgcgccggta tttttccgga
    51001 aatcaccgcc aatcagtaga atttctggtc catctgcttg agcaagaata tcaaaaactg
    51061 gataattatt tgtaatgatc cgaattttct tgttcagtaa atgcgtcgcc aatagttcga
    51121 ttgttgtacc tggtcctaag aaaatcgttt ctccctcgtg aatcaaggag gctgctgtgg
    51181 cagcaatttc ttttttttct tgaatctgca gagtggcttt ttcagtgtga gaaagttctt
    51241 gatctaaagt gtaggaaaga ctttgagccc ctccatggac acgcagcagc ttgcccgatt
    51301 tttctaattc atctaaatct ctgcgaacgg tcatatcaga aacatctaat tgattgatga
    51361 tttcattaac ggtaaggatt ccttttttat tgaccatttc tacgatagta agcaatcttt
    51421 cttttttcaa cattgtcttc acctctaatt taaggataat ctatcatata aacggacaac
    51481 agtcaatcta attcgaacaa aagtaaacat ttagggtggt ttttatgttt gttacaatag
    51541 attttattgc tgttttctgg tttttatgat tatttgtgtt tgtttttgtt gacaaatgtt
    51601 ttggatgcgt ttacaatgca atcagttaga aagagcgaaa actgattata gatttgagga
    51661 gagatgtaca tgcttaaatt accagaagat tttatttttg gcggagccac agcagcctat
    51721 caggttgaag gagccactaa ggaaggtggc aaaggcgctg ttgcttggga tgacttttta
    51781 gaggaacaag ggcgattcag tcccgatccg gcaagtgatt tttatcatca atatgcaaag
    51841 gacattgaat tgtgtgaacg ttttggtgta aatggtctaa gattatccat tgcttggagc
    51901 cgcatttttc ctgatggagc tgggaaacca aatccagaag gaatcgcttt ttatcatcgt
    51961 gtgttcgaag aatgtaagaa aagaaacgta acgccgtttg tgacgttgca tcattttgat
    52021 acccctaaac gtttgtttga ccatggagat tttttgaatc gagaaacaat agaagcattt
    52081 gtttcctatg ccattttttg ttttcatgaa ttcaaagaag tcaaggtgtg gagtaccttt
    52141 aatgaaatct atccagttgc aaccaatcaa tatttgttag gtgttttccc accaggaatc
    52201 aaatatgatt ttacaaagat cgtcgcctgt cttcataata tgatggttgc tcatgcccgt
    52261 gtagtgaact atttcaaaga aaacgaactt ccgggtgaaa ttggtgtagt tcactcatta
    52321 gagacgaaat atgcggcaac agacgcgccg gaagataagc atgctgcctt tttagacgat
    52381 gcattgtcga tccgtttctt attagatgct acctatttag gctattattc aactgaaacc
    52441 ttgactgctc ttgatgagat atgtgaagca aatcaggcca gctatcattt tcctgaagaa
    52501 gatttcgttg aattgaaaaa agcatccacg cgtaatgact acttagggat caatcactac
    52561 caatgccatt ttgtcaaagc ttacgatgga gaaaatgcaa tccatcataa cggtacgggt
    52621 gaaaaaggga cctctgttta taaagtgaag ggaatcggag aacgtattta taaagaagga
    52681 attcctcgaa ctgattggga ctggctgatt tatccagaag gtctatatga cttgttgctg
    52741 cgaattaaaa gcgattaccc acattacaac aaaatctata tcactgagaa cgggatgggg
    52801 tataaagatc agtttgaaga tggcattatt atggatcagc cgagaatcga ctatttgaga
    52861 gtctatttgg aatccttaag caaggcgata acagccgggg taaatgtgaa ggggtatttt
    52921 ttgtggtcgc ttatggatct tttctcatgg acaaatgggt ataacaaaag gtatggcttg
    52981 ttttatgttg attttgaaac ccagaagcgt tacccaaaag aatcagctta ctggtacaag
    53041 ttggtcagtg aaaccaaaac gattatttaa taagtgataa tggaggaaga aaagatgaat
    53101 aaagaggaat tacaaatgct tggttttgag atcgttgcat attcaggcga cgctcgcagt
    53161 acattattga aattattgaa agaagtaaga caaggaaact ttgaacatgt tgattcggcg
    53221 ttgaaagaag ccgacgaaaa tttaaccctt gcacataatt cgcaaacaaa aattttagcg
    53281 gaagaagcat ctgggaaaga gatggagatg ggattcattt ttatccatgg gcaggatcat
    53341 ttaatgacca ctttattgct gagagatctg attcaagact ttattgtact gtacagacag
    53401 aatcaaggat aggagaagaa cgctatggat ggaatcatta aacaaatcga aaaagggaaa
    53461 ccattttttg aaaaaatctc acgtaatagt tatttaggag ccgttcgtga cggattttta
    53521 acagcgatgc cagctatttt attttcaagc attttcattt tgattgctgc ggttcctgag
    53581 atttttggtt accaatggcc tgaatctgtc tccacatggc tatggaaagt ctataattat
    53641 tcgatgggtg ttgtagggtt actcgtttca gcaaccactg ctcgctgctt ggctgattcg
    53701 atgaatcgtc gcttaccgaa aaacaaagta atcaacacca cctctgtgat gctggcctct
    53761 gtggtaagtt tcctgttgtt aagcgtctct ccgattgaag gtggattttc aacggaatat
    53821 atggggacaa agggactact ggcttccttt gtcgctgcat ttttaacagt taatttatat
    53881 aagttttgtg tgctgaaaga tattaccatt aaaatgccta aagaagttcc tggaacgatt
    53941 tcgcaaacct tccgagatat ttttcctttc tctttttcag tatttgcggc cgttttaatt
    54001 gatttaggca ttcgacaaat cttccaaatc tcatttgcag aagcaatcat tacggtgctg
    54061 cagccgctat ttacagcagc tgacgggtac ttaggaatcg ctattatctg gggagcgatg
    54121 gcgctgtttt ggtttgtcgg tgttcatgga ccgtcgatcg tggagccggc aattgcggca
    54181 attatctatg ccaatgtgga aaccaatctg caattgttca attccggtga acaagcttct
    54241 aaagtactga cggtgggttt agggaatttt gtaggaacta tgggaggaac tggggcaaca
    54301 ttggttgttc cttttatctt cctactcttt gctaagtcta agcagttgaa ggcagttggg
    54361 aaagcttcct ttattccagt aagtttcgct gtcaacgaac cattgctatt tgcggcaccc
    54421 atgattttga acccttattt ttttattcca tttttgttaa cacctgttgt aaacgtttgc
    54481 ctgttcaagt tttttgtcga tgtattgggc atgaacagct ttatgtacgt tttgccttgg
    54541 gcaactccag caccgatcgg tttggttcta ggaacgggca tgggtatctt agcttttgtt
    54601 ctagcagcgg ttctaatcgt cgttgacttc ctgatctatc taccattttg caaagcatac
    54661 gatgctgtct tagtagagaa agaagcacaa aaagcagagg tgatcgcaac cgaggaaggt
    54721 gcttctgccg atgtacgtga ggaagtacct gtggcagcga gtcaagttat cagcgatgca
    54781 aataaagaaa tcaatgtgtt ggtactttgt gctggcgcag ggacaagtgc gatgttagct
    54841 aatgctttaa aaaaaggtgc atctgaatcg aaagcaccga tcagtgcaat ggcgggtgct
    54901 tatggttctc attacgaaat gctgcaggat tttgatatgg tggtcttagc accgcaagtc
    54961 aattcttact atgatgatat caaagaagac accgatcgct taggaatcaa gctggttgcg
    55021 acaaaaggag cagaatatat cggattaacg agagatcctg aaaaagctgt tcagtttatt
    55081 ctgaaccaat ttcaataaag gaggagccat aatgaaaatg ggaatttggt tgcgtaaagc
    55141 tgttttattt gcagctgtgt taggggcttt gggggctgtt tcaaaaactg ttgaagcatc
    55201 tgccagcgaa tttattcgcg gagcagatat ttcgatcctg tcagatatgg aaaaatctgg
    55261 tgcaaaatat tatgaagacg atatttcaaa agatgcctta gagattttaa aaaataatgg
    55321 tgtcaactat gttcgactgc gtttgtggca ggatccttat aatagtaatg gagaaagtta
    55381 tggagcaggg acaaatgatc tggaaacgac gattgacctt gcaaaacgag caaaaaatct
    55441 gggacttaag gtgctgctgg attttcacta cagtgatttt tgggttgatc ctgggaaaca
    55501 gaatcttcct aaagcatggc aaggtctgac ctttgaagaa atgaatacgg cattgtacga
    55561 ctatacaaag aacgttctgt cggaaatgaa gcagctggac gtttatcctg atatggttca
    55621 gatcggcaat gaactgaata gcggaatgct ctggccttat ggcaagtctt ggggagaagg
    55681 cgggggagaa tttgatcgat tggctgcttt tttgaagtct ggtatccaag ctgttcgaga
    55741 cactcaacct aaaacaactc cagtaatgct ccacttagct gatggtggcg atacaggagc
    55801 atttacttgg tggtttgatg aaatcacgag tcgaggtgtg tcatttgatt taattggagt
    55861 gtcgtattat ccgtattggc acggttcaat gaatgaactt caaaccaata tgaatgcgat
    55921 cagccaacgg tatggtaaag aagtgatcgt agttgaaaca gcttatgggc atacaacagc
    55981 gaatgccgat actatgccaa atgcttttgg tgaagccgaa gcagctgcgg ggggatatga
    56041 accaacaccg acaggacaag cagagtattt gctggatctt gccgatcgga ttcaggcagt
    56101 accgaataat cgcggggcgg gcttcttcta ttgggaacct ctttggtaca acggaaatgt
    56161 gagttgggca acacaagcag gtatgaatta tctcagtgtt caatccacta tgggaaacga
    56221 atgggacaac caagcgatgt ttgattttgc tggaaacgcc ttgccaagct tgcgtgcgtt
    56281 taaacaagca ggggcgcaaa taaatctagt taaaaatgca agtttcgaaa gcgatggacc
    56341 aacgaccagt ccttccaatt ggcaaacctg gtttcaacaa ggaaccgcta agggtacgat
    56401 caaaacggaa gcgggcactt tttttgggga ctacaaacta actttttggc aggatcaagc
    56461 atacgaggca tcagcttatc aaaatgttag tggcataagc aaaggaactt acacattgag
    56521 tgcctatgta atgtctgggg gagagtttga tactaatcag ttatatatca aaaattatgg
    56581 tggagcggaa ctaaatactg cggttgttaa aacaagtgaa tggacaaaaa ttacaatcaa
    56641 agacattcca attacaacag gtgtttgtga aattggggtt tatagcaagg cttcaggaaa
    56701 tgcttggacg aacgttgatt ttgtttcatt ggtgaaacaa tagactgcgg atcgtttcga
    56761 ttcaagatcg gaggttccct tcagccacat cgttagcgta gaaggcagga atcgaacctg
    56821 cacctcgcct ttgccaaaaa taaccagaaa cgatttccag tcatttttac caaaacgagt
    56881 aaagcaccag acttcatcta cactttgtat tatgctaaag agagttcaac gatttcgtaa
    56941 gaagcaatga aaaaattgca aaaagttgtg cagataacat aaagtttgtt taagaaaggg
    57001 taaccttaga attccgtcgt gaatatgatt tgagcactta gatggataga aaaaagttct
    57061 cggaaaacag ttcgtttttc gagaacttct ttttatgata agaatgaaac aaattaactt
    57121 atattatagt ctcttttggt agggaaccat cttattttta atgaaaatca agcattttag
    57181 ctattgaaga atgttgattt atagggattc cccctccata ttatgttggc tctttattcc
    57241 cactctgttt tcaacgtaaa gtgtataaaa cagaatgcga tactatcaag ggagttaaaa
    57301 caatatacag aacagtaaaa cactataaat aaaaataaaa gtgcaataaa agtgcaattt
    57361 ttgcacctaa tcatactctg tttatatatg aaaactagat tctgaatcca atatttggtt
    57421 aacgagaggc gttcgaattt gaacgtcttt tatatattac tttcaaataa atatgaggta
    57481 gaatactatc tattttcttt ttaacccaat tgttataatg gagagtgtaa aatattttgt
    57541 gtaaatagaa aaaaggaagt cccttctgta gaatagagtt accacaacac attcacagaa
    57601 gagaggactt ccctatgaac gattttacta cagaaattct aaagactcta gcgaacaaag
    57661 gcgatttgaa tgaattattc cgtgtccatt tggagaaagc agtcaatacg cttctcaaaa
    57721 cggagttaac ggctttccta gattacgaaa agtatgatcg cattggtttt aacacgggta
    57781 attctcgtaa cggctcctat gaccgtacgg tcaagaccga gtatggggaa cttcatctcc
    57841 agattccgcg cgaccgcaat ggtgagttca agcaacagac tgttcctgct tatagacgga
    57901 cgaatgacac gttagaggag accgtcattc acctcttccg aaaaggtatt accatgtcgg
    57961 aaatcgcaga cttgattgag aaaatgtatg ggcattacta cacgccccaa accatgtcca
    58021 atataacaaa atcatttaca gaagaggtaa cggcgtttaa tgggcgggag cttcatgacc
    58081 gttatgctgc tatttatatg gacgcaacgt atattccgtt aaagcggaaa accgtcgcca
    58141 aggaagctat tcatatcgca gttggcattc gcccggacgg atcaaaggaa gtattgagct
    58201 atgcgattgc accgactgaa tccatcacga tttgggagga aattttattg gaccttcaag
    58261 agcgcggttt gaaaaatgtc ctcctgttca tcacggatgg cttaaagggg atggtaggag
    58321 cgattagtcg gttctatccc aaagctcgtt ttcaacattg ttgtgtacac gtttcccgta
    58381 atatcagtca taaagtgcgt gtcgatgatc gtaaggaagt ctgtgatgat tttaaaatgg
    58441 tgtatcaagc ctcatctaaa gaggtggcgt tggaagcacg tggtactttt gcggaaaaat
    58501 ggaaaaccag ctatccaaaa gtggttgaat cgattctttc gaacgatcac ttgctcactt
    58561 tctatgattt ccccttggcc atacgcaaga gtatttattc tacgaacttg attgaatcct
    58621 ttaataaaca aatcaagaaa tacagccacc gcaaggaaca gttccaaaat gaagagtcga
    58681 tggaacgttt cttagtctcg tcttttgata cttacaacca aaaattccta ggtcgcagtc
    58741 ataaaggttt ccaacaggcc gaaggcgagc tcgaacaaat gctaagccaa ctgattgaga
    58801 attagaaaca atctgcagta gggaagaatc atttacacaa aattattgac gctcccttat
    58861 aatgagaact tttactaaca taatttatga taaacttact atataatcat attaattaaa
    58921 tagttaggag atctgcttat gtttatatct actcttcaaa ttcgaaattt tagaaattat
    58981 gaatccgaaa tctttcgatt cgataatgag acaaatacta ttataggtga gaatgattca
    59041 gggaaaacca atgctcttac tgcattgaga atcttattag atgatagtta ttactatagt
    59101 agtaaaacac taaaagaatc agattttttt catggaattc aaaatgggtg gcaagggcat
    59161 tggattatta tctctgcgac atttgaagga atcagcgaag aagaatttga caatgagatt
    59221 tgtgcttcca tttctttaaa ttctgaaagt caaacaatct tagaagaatt gatttcaaat
    59281 gcagataaag gtgtaggtag tatttctcta tttattagac ctaacaaagc tattagaaag
    59341 caattatttg atatttccac tgaattagac tctcatcaat ttaacgaatt tagaaattct
    59401 attcgtctat ccgactatga attttactac acatctaaat caaatctaaa tttctgtatc
    59461 aatgaaaatt atgataaatt ggtaggaaga ctcaatgaca atatagctag taatcctgaa
    59521 gaagacgatg aagctctgtt gggctcaaga attgacatgt cagatatttt caagcatatt
    59581 tcggttgttt atgttgacgc tcttcgagat gttcttagag aaatgaaaaa caatcgaaac
    59641 ccagtcaaaa gaatcatgga aacaattgaa tcaaaaatat catcagataa tgttgagtca
    59701 ttaaaaacaa ttatacagca attaaatgag actattacca gtgttcctga aattaggaaa
    59761 attggcgaaa atattaatcg gcaactaaat agcataattg gttcagtgta ttctcctaat
    59821 cttcttcttt cctcaactat gtcagatgat atgggttctt tagcaaaatt tctttcaatg
    59881 aagccagaac aaaatatcga cttagactta ctagggttag gacatctaaa tatgatttat
    59941 ttagctttga aaatagtcga atttgaagcg tgtcgttcaa gagaactact taatattatg
    60001 ttgattgaag aaccagaagc tcatattcat catcatattc aaaaaactct gttcgaagga
    60061 ttaaatcttc aaaaaaacta tactcagatt ctcatgacca cacattctgt acatttagct
    60121 gaagtgtctg aaatatctcg gatgaatgta ttaaaatcgt ttaatggcaa atctatcgtt
    60181 atgaatccag caaataatct gaactcattt gctaaagaaa agttaaaaaa gaacaatcta
    60241 aatctaataa acgcagtaga gagatattta gatgttaaaa gaaatggatt gcttttttct
    60301 aaaggtgtta tcttagttga aggagatgct gaagaaatac ttattcctca aatagtaaaa
    60361 aaattatttg gtataaactt agacgaactt ggaataggtt tgattaatgt tggtagtact
    60421 tcgtttgaat atatcgctag cttgtttgac gatgatagaa tacagagaaa gtgtgctatt
    60481 gtaactgatt tagatgaaca ggcaatccca tcagaacatc gattgtataa aagcactgca
    60541 caagagaaag gtcaagcaag aaaagaaaaa ttatcctccc tttttaatga aaacaattgg
    60601 gttaattgtt tttatgctaa tacaacattt gaaattgagt ttttagatgt gaataaagaa
    60661 aatattctaa cttatgtcag tccaattata gatgacgcat tcaaagataa aaaaacaata
    60721 actgcttata aagaagaaat acaaagtgaa caatatttag aaagaaattt agcgatgtta
    60781 aaactagcca atcatgttgg taaggggtgg tttgcaattg agttaggtga aaaaattgac
    60841 tttttaatca aaattcctaa gtatattctt aatgctattg cttttgcatg tcaggaaata
    60901 gtagatctct caatttataa aaaaattcta ctccatacaa tcgacttgta cgaggaaact
    60961 acagaattgt cagctttatc agctagttta aaaacaagtg atacagctga tttgaatata
    61021 gcaataattt ctttattaga gtactttggt aaagatgagg atgttgtgta tctaatcaat
    61081 cagatagaaa attacacaaa aatactttat gctgaggttt caaaatgaca aatatcttcg
    61141 aaaaaatcgt aaatgattta aatttagaac aaaaagatgt tgtggaaagt gaagataacc
    61201 tttatgtaaa tgcatgtcct gggagtggga aaacaagggt acttacaagg aaaattgctt
    61261 accaagcaat taaacacgat ggatcactaa aaagaataat tgctatcaca tacactaata
    61321 gagctgctga agaaattaag gaacgcctaa gtttacttag tatagatgat gatattaata
    61381 tttgggtggg gacaatacat cagttttgtc ttgaatttat tatttatcct tttaaaatga
    61441 atctctcaag agtatcaaaa ggatttacaa ttattgatga ttatactcaa agagcttacg
    61501 tcagccaaat taataatatg ctgaatttaa atctcaaaac gtatgaactg aacaaaattg
    61561 atttgtcact ttctcatgat tttaaaatta atgaagttca gtatactcaa gtttctgaaa
    61621 tgtatcacac tatgttggaa aaaaataaag aaattgattt tgatatgatt ttactagtag
    61681 cgtataaaat tttaactgta aacagtaacg ttgcacgtaa tattgctagt aatataaggg
    61741 cgatttatgt ggatgaattt caagatacta gagaattaca atacaatgta atagctaaat
    61801 tacttcaaaa caaccctcaa attcagtcaa tgtttgttgg agatattgac caagcaattt
    61861 atggatcatt agatggtata gctaaatcag ttgaagaact agaaatgcta actagtcaca
    61921 cttttcaatc aaagacgcta catggctgtt acaggtctaa tcagagatta gtagacttct
    61981 actctaattt tcagagttgt ccttacgaga ttgaaagcag agggaataat aaaaacgacc
    62041 gtggttttat aagttatgat tgcaaagtta ctaaggagga tttacccaac ataataaaaa
    62101 atataataaa ggaaaagatt gaaagcggca ttcatgaaaa agatatttgt gtacttgctc
    62161 ctcaacacta tcctctgttt tcactgggtg agtatttaaa gaaagaatta ccgtattgca
    62221 attttgatgc tataaatata tcaccaatta aggtaaataa tcatagttta tttttcaagt
    62281 tagcaatttt gtactttact gaatcaggtg aaaaggttcg
//
LOCUS       DAJSMK010000008        59510 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.008, whole genome shotgun sequence.
ACCESSION   DAJSMK010000008 DAJSMK010000000
VERSION     DAJSMK010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.008"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(324..1634)
                     /locus_tag="ON488_000506"
     CDS             complement(324..1634)
                     /locus_tag="ON488_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCR3230725.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1646..3064)
                     /locus_tag="ON488_000507"
     CDS             complement(1646..3064)
                     /locus_tag="ON488_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3230726.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3304..4872)
                     /locus_tag="ON488_000508"
     CDS             complement(3304..4872)
                     /locus_tag="ON488_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCR3230727.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4876..5286)
                     /locus_tag="ON488_000509"
     CDS             complement(4876..5286)
                     /locus_tag="ON488_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HCR3230728.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5283..6206)
                     /locus_tag="ON488_000510"
     CDS             complement(5283..6206)
                     /locus_tag="ON488_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HCR3230729.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6203..7081)
                     /locus_tag="ON488_000511"
     CDS             complement(6203..7081)
                     /locus_tag="ON488_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HCR3230730.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7068..8405)
                     /locus_tag="ON488_000512"
     CDS             complement(7068..8405)
                     /locus_tag="ON488_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HCR3230731.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8408..9511)
                     /locus_tag="ON488_000513"
     CDS             complement(8408..9511)
                     /locus_tag="ON488_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HCR3230732.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9585..11093)
                     /locus_tag="ON488_000514"
     CDS             complement(9585..11093)
                     /locus_tag="ON488_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCR3230733.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11059..11751)
                     /locus_tag="ON488_000515"
     CDS             complement(11059..11751)
                     /locus_tag="ON488_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCR3230734.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11773..12747)
                     /locus_tag="ON488_000516"
     CDS             complement(11773..12747)
                     /locus_tag="ON488_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3230735.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13047..13919
                     /locus_tag="ON488_000517"
     CDS             13047..13919
                     /locus_tag="ON488_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3230736.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14377..16575)
                     /locus_tag="ON488_000518"
     CDS             complement(14377..16575)
                     /locus_tag="ON488_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3230737.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16807..17799
                     /locus_tag="ON488_000519"
     CDS             16807..17799
                     /locus_tag="ON488_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3230738.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17859..19280
                     /locus_tag="ON488_000520"
     CDS             17859..19280
                     /locus_tag="ON488_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HCR3230739.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19273..20772
                     /locus_tag="ON488_000521"
     CDS             19273..20772
                     /locus_tag="ON488_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HCR3230740.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20811..22205
                     /gene="uxaC"
                     /locus_tag="ON488_000522"
     CDS             20811..22205
                     /gene="uxaC"
                     /locus_tag="ON488_000522"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HCR3230741.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22364..23047
                     /locus_tag="ON488_000523"
     CDS             22364..23047
                     /locus_tag="ON488_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HCR3230742.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23049..23885
                     /locus_tag="ON488_000524"
     CDS             23049..23885
                     /locus_tag="ON488_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCR3230743.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYHIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23896..25650
                     /locus_tag="ON488_000525"
     CDS             23896..25650
                     /locus_tag="ON488_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230744.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25926..26267)
                     /locus_tag="ON488_000526"
     CDS             complement(25926..26267)
                     /locus_tag="ON488_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCR3230745.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26335..28506)
                     /locus_tag="ON488_000527"
     CDS             complement(26335..28506)
                     /locus_tag="ON488_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCR3230746.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28675..29574
                     /locus_tag="ON488_000528"
     CDS             28675..29574
                     /locus_tag="ON488_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCR3230747.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29645..30502)
                     /locus_tag="ON488_000529"
     CDS             complement(29645..30502)
                     /locus_tag="ON488_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCR3230748.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30487..33189)
                     /locus_tag="ON488_000530"
     CDS             complement(30487..33189)
                     /locus_tag="ON488_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HCR3230749.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33202..34491)
                     /locus_tag="ON488_000531"
     CDS             complement(33202..34491)
                     /locus_tag="ON488_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HCR3230750.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34641..35687
                     /locus_tag="ON488_000532"
     CDS             34641..35687
                     /locus_tag="ON488_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3230751.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35689..37842
                     /locus_tag="ON488_000533"
     CDS             35689..37842
                     /locus_tag="ON488_000533"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HCR3230752.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38315..39766)
                     /locus_tag="ON488_000534"
     CDS             complement(38315..39766)
                     /locus_tag="ON488_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3230753.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39763..41487)
                     /locus_tag="ON488_000535"
     CDS             complement(39763..41487)
                     /locus_tag="ON488_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCR3230754.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41480..42094)
                     /locus_tag="ON488_000536"
     CDS             complement(41480..42094)
                     /locus_tag="ON488_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HCR3230755.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42439..43896)
                     /locus_tag="ON488_000537"
     CDS             complement(42439..43896)
                     /locus_tag="ON488_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3230756.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43937..44857)
                     /locus_tag="ON488_000538"
     CDS             complement(43937..44857)
                     /locus_tag="ON488_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3230757.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44869..45816)
                     /locus_tag="ON488_000539"
     CDS             complement(44869..45816)
                     /locus_tag="ON488_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3230758.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46295..47014)
                     /locus_tag="ON488_000540"
     CDS             complement(46295..47014)
                     /locus_tag="ON488_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCR3230759.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47063..48709)
                     /locus_tag="ON488_000541"
     CDS             complement(47063..48709)
                     /locus_tag="ON488_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCR3230760.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48888..49478
                     /locus_tag="ON488_000542"
     CDS             48888..49478
                     /locus_tag="ON488_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCR3230761.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49570..51075
                     /locus_tag="ON488_000543"
     CDS             49570..51075
                     /locus_tag="ON488_000543"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HCR3230762.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51159..52511)
                     /gene="celB"
                     /locus_tag="ON488_000544"
     CDS             complement(51159..52511)
                     /gene="celB"
                     /locus_tag="ON488_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCR3230763.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52511..53029)
                     /locus_tag="ON488_000545"
     CDS             complement(52511..53029)
                     /locus_tag="ON488_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230764.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53045..53371)
                     /locus_tag="ON488_000546"
     CDS             complement(53045..53371)
                     /locus_tag="ON488_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HCR3230765.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53384..55363)
                     /locus_tag="ON488_000547"
     CDS             complement(53384..55363)
                     /locus_tag="ON488_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCR3230766.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55384..55698)
                     /locus_tag="ON488_000548"
     CDS             complement(55384..55698)
                     /locus_tag="ON488_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HCR3230767.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55866..56159
                     /locus_tag="ON488_000549"
     CDS             55866..56159
                     /locus_tag="ON488_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HCR3230768.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56237..57349)
                     /locus_tag="ON488_000550"
     CDS             complement(56237..57349)
                     /locus_tag="ON488_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCR3230769.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57736..57915
                     /locus_tag="ON488_000551"
     CDS             57736..57915
                     /locus_tag="ON488_000551"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230770.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58109..58279
                     /locus_tag="ON488_000552"
     CDS             58109..58279
                     /locus_tag="ON488_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3230771.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58703..59443)
                     /locus_tag="ON488_000553"
     CDS             complement(58703..59443)
                     /locus_tag="ON488_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCR3230772.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17798 a        12165 c        10403 g        19144 t
ORIGIN      
        1 atcagagaga caaacgattg tcaactcttt tttaaaagtt tttttcgatt tcgtttttcg
       61 aaatctttca gcaactcatt tatcataact tatcgtttgt tatttgtcaa gaactttttt
      121 gaagtttttt tcgatagaat caagcttcgc aagtggttct ttttaacgac ttagttatct
      181 tatcacgtct aaaaacatgt gtcaactctt ttttggaatt ttcataaaat gtttcaatga
      241 agcgcgacaa cgttgtttaa tatatcatta aaaaaaataa aggtcaagct aaaatattat
      301 ttaagcttga ccttattata atttcaacga ttgtcaaaag tattgtttgc agctgtgttg
      361 ccagtttcta tagataaatc acagcttttg aaacataagt tttgtactgc ttcgattcgc
      421 ccgaattctt ttgcagttat ttggcaatga gaaaagcaga catcttctat aggcttttca
      481 ggaaatgcta ctaaatcaaa agctcgggaa ggaagtgagt aacctggaga aaggcatgcc
      541 tgtacgtttt tgatgtgtat gtctttgact ttcgtcattt gctttgattc aggtatttct
      601 tcagccactg cttgccaact ttctggcatt tgagcaaggt cattgctatt ttttctattg
      661 tattcattat gccagtccat tatccaagaa aaaggaaatt gtacatcaat catattcaga
      721 ttttctaccc tgatattttc gatcactccc cctctttctt ttgaagattt cattcgaata
      781 ccacagtctg actgaaaaaa atcgatatcg tgaatatata cgtcactaac tccagcacta
      841 acttcgctac caatagttac accgtatcct gaacggattt tacatctagc aacctcgatt
      901 cttgatgatt ttcgattgac tcttgcacca ttgccatctc tgccagactt aatagcaata
      961 caatcatcac cacaggccaa atcacattca tagacacgca catttgttga agaatcaata
     1021 tcaatcccat ctgtacttgg tccatcattg ttgcggatga ttactttttc tactaataca
     1081 tcgttagaat aagtgatttg caagttccaa aaacctgatt tctgaaaaat caaatcacga
     1141 acaacaacat gttctgcatg atacagtaaa caagcgcgtg gacgtttaat agcataatcc
     1201 gcaatccaac gaagtccctt ttgatcgtat tcagctcttg tcccgctttt ttgatctttt
     1261 ccccaataca gctcccacca atggtctcct tgaccgtcga ttattccttt tccttctata
     1321 agaatatctt tcgccgagag aacattcaaa atcgctgctg gccatttcat ttctacgccg
     1381 gctactcgtg tatcgatttc tggaaatgct tcgatatctg ttctcccctt gaggactgca
     1441 ccttcttcaa agataagatg actcttatct tttaaaaaaa gggctccgac taaataaatg
     1501 ccttttggaa taaatacagg taagtgttct ttcgcacctt gatcgattgc tttttgcagt
     1561 attattgtat catcttgttg agtgtcgttt gttttaaagt tcaaagcatt gataatccct
     1621 ttttttgtcc gcaatacgtt tctccctatc tttcattgat ttttttcaat tcttcaccaa
     1681 taaatacagt ttttgaacga ttcagtgggt aacctactag caaaatgatt gcggatacaa
     1741 ataagcagaa tgctggtaac aagtttgcca tcgtataaat cctttcttgt actaaaactg
     1801 attggatggc tccacctgtt gtagacgatt ggtaaccaat gagtgccagc ataaatccgc
     1861 ctaccgctcc tgcacatgct tgtcctactt ttctcgcaaa agaatttact ccatatactg
     1921 ttccatcttc tcttaagcct gtcttatatt gatgataatc aatcacgtca gtaatgaatg
     1981 cccagaccat caaattgaat aaaccagatc ctaaagtagc gataaataaa agaatcagat
     2041 atacccatgc atttgttata tgaaggaaat acatcagcaa gtacatacat gaagaagcaa
     2101 gtaacgcaaa tacgcttgct tcctttttac caaataattt tgtcagcttt gtagcaaatg
     2161 gtgctaaaac tactactgtt ccgtaagtaa ataaaagagc aacagacatt gcttgtttat
     2221 tatggaagta atcattgaat aaataagtca tattcgtccc agctaaaatc tgattgatca
     2281 caatgaaaat gtcaacaatg actaaaataa tcagtgctcg attagctaac aaacctttta
     2341 ccaactgaga agcagatact ttttcgtttt tgacaactct tactctttca gtagtcaatt
     2401 tacaagttaa catatatgcg acaaatgcta ttgcagcaca tccgattgaa atccaaaaga
     2461 aatgattccc tgaaacgact tgttgtccac tcttgttatg ggtatacatt aaaatcggaa
     2521 tgaagaatcc tgtagttgat ccgccaatcg cagaaccaat gcttcggaac gtggacaacg
     2581 aggtgcggtc attaggattt gagctaattg ctgctgccat tgctccatac gggatattga
     2641 ttgttgagag aaaaatccca taaacaatgt atgaaacaaa aatataagca atcttcaccg
     2701 tcattggaag atgttggacg aatggcaaaa acaaaatgac agtcactaag caaaatggat
     2761 acttcatttt tctgatccaa ggaataaatc ggccagtttc tgttaactct gagacatcac
     2821 ataatcttcc aaccatcaca tcagcaaacg catccaaaat tctcgaaatc aagaataacg
     2881 tacctacgat tgcccctgaa acgccaagaa cattcgtata ataaatcatc aagaaactat
     2941 tgactaaacc taaaataaaa cagttaccta gatcaccgaa catgtagcct atcttatcgg
     3001 aaatcccaaa ttcctttttt tcttttttta ttgtatttgc tgtaacagca ttttgtgaaa
     3061 gcatttgaat tcctcctacc tcttctagta aacgttttca aaattataac tctttttttc
     3121 ttgtttttat attcacaatg ttggcttttt attgcattat cttgacagat aaaaaacaaa
     3181 aaataatcta aaaacattga tgcataagat tgataacttt ttttacataa caatatatac
     3241 aaacaaaaaa attcactaac tagtgaaaat aagttagtga acctcattta ttaaagaatt
     3301 aaattacaga tgatcttttc catcatactt gaaaaactca aaatcagcat aacttcctct
     3361 ttttttattt agatcatgca ctgctatccc gataaaattt ccagtaaacc ctcctgagag
     3421 tatacacatg tttttttgcg gacctacttt cttccattct tcagttgata cgtctttcaa
     3481 atgaaactgt gctgtctctt tctttacagt gactttcaaa aaagtcttct tttctgtgag
     3541 tggaatcgtc caatcttcta tttgtgctac tccgttttct gattctatca tacgtaggca
     3601 ttttcccttg tcctcattcc aagtaacata acaataaata taattggatt catttaagta
     3661 cagtaccagt ccagccatct gattaaaatt attaggcatg tattcaaatg ctgtctccgc
     3721 atcaaaagta aaatccgttt gccgaatagc taacaaatga tgttcgaagg tagattgaag
     3781 agattcaccg gaaatcagac gtaaaaaacc tggtctacat tttgtatcac accaatcagc
     3841 atttggcaaa atgcgtctgg cattccagtt cttctttagc tctccttcaa atgtatccat
     3901 aaactgatga tctttttctt gttgtacctc ttcatttgtc tcaatcatta tttcttccat
     3961 cggagttgtc tggctatctt taagtcttaa ccaatcgtcg gacgtccaat acacttcttg
     4021 aatagcggtt tctcttccca aaatagccgc accgtttaat ggtctggtac aaagatatgt
     4081 catgtaccat cttcctgacg gggtttgtac taagctccca tgtcctgtac attgcaatgt
     4141 agaagcaggt ttgtcactag ctgtcagcat aggaaaacca ggatcaagct cgtaaggacc
     4201 agtaatattc tttgctcggc aaactgtaac tgaatgtcct cttcctgtac cgccttctgc
     4261 cgtcatcaaa taataatacc cgttacgaaa atacaaatgt ggtgcctccg ttttcgctaa
     4321 ttctgtacct gcaaatattt tatagatggg accatcaagc ttcttcttct ctgcatcata
     4381 ttcttgtaat acgataccgc tggatttatt cggtgtgtcc agacgataat cccatagttc
     4441 attgacaagc catttttttc ccgtttcaag atcatggaac aaagaaggat caaagccgtt
     4501 actatttaaa taaattggtt cggaccaagg acctgtgatc tcagatgcag tgatcaaata
     4561 attgtggaca tctttaaacg gacggcctgc acttttgaca tctgtgtaaa caagataaaa
     4621 caatccatca gcataactga tctgtggcgc ccatatactt ccatttgtag gatttccttg
     4681 caaagatact tgagtggtca aaatatccgt tgtatgtgac cagttgacta aatttttcga
     4741 ctcatatact cggattcctg gaagccattc aaaagaggag acaataatgt aataccgctc
     4801 tttcactctt aatatattag gatctggatt gaatcctctt aaaataggat ttttcacttt
     4861 gatagtctgc atgattcagg ctccttttct cattcttact cgatataaac tgaatgcccc
     4921 agctgcgaaa taaaaaaatg caaaaggaaa cgcaataaac tgagtgccaa tcaacaatat
     4981 gaatcctgtt ataaaataca aaccagtggc agttgttaag tattttcctt tagcagtcaa
     5041 aaacaatgct actgctaaaa aagcaagtga aataaacaac acaacggcaa acagaccagt
     5101 catgtcctgt aataatccaa atgtattttc taaagacaaa gttgaatgat ctacagcaag
     5161 cgactgataa ctttttttaa actctgacgc agacatatta cttaaagtaa ctgctaaccc
     5221 gccaaagaaa atcaaagata gactgccacc gaccattcct agcaatagtt cccattttct
     5281 tttcatttct gaaccccctg cttttctaaa tgtatccatt caggtctttt gatcgatgtt
     5341 tcataattgt tattacgttc agagaatttg acagtctgtt catttttctt gtcatcccaa
     5401 ttatcccaac cagttgggtg aacatgccca cctatcttac acgcttcaaa taagacattt
     5461 gcatacggac gccacggtct tcctaaatag acgtttctag tatcaggttc tgcagtcaag
     5521 gtacagcttt caaaacgata ccctgttttt tgatttttcg gcgtagatgc tgctgtgatg
     5581 tatccaggat ttttactggc taagctatgg atatgacact gatgaaaaac ggcatctgcc
     5641 ccaccaaata tgaaatccac cgttccttca atccagcaat attcataggt ctgacgacaa
     5701 tactcaggat tggcagaagc cggtgtacaa aaaggagtac catctttttg caaatcaggc
     5761 aacggacccg tgcataaggt atcctgataa ccagatagtc gacagttttt taaagatacg
     5821 cgatctcctg aattgaataa agcaacagcc tgtcctacct tttctcctgg acctgctgta
     5881 ttttcgatgt gaagattttc taatacgaca ttcgatcctt ctaagaaaaa agtagcactt
     5941 cggaaagtcc ctaactggct accgtcaaga tactcctgtt ttgcaaaacg attaccggag
     6001 ataactactg ttcctgctcc cacaagttta aaattggata atctgctttc tatatattca
     6061 tcatatcttc cttcttttac tatcaagacc tttggatggc tatccggcag gcctgccaaa
     6121 taatcgattc cttcttggat agtttcaaaa tccgtcgggg tatctatagc attctttcca
     6181 attatcagtt tgtctttcat cctcataaat gctcccttat gaattgtttc caaatatttc
     6241 tcatttcttg tgtttccata tgaccgcctg ttaaagaaaa agaagaaaag ttttctggac
     6301 tacccattga ttgatacttt ttgtccagcc cttttctcag cttcagtacg ccttcgtcca
     6361 agcacatcgt atcgtttttt ccaactaagc taagacgagg gcgcggagcg attttttctt
     6421 ggattgctaa cgttgtataa gctgtcaata gatttggcac atagtaataa aacccatgat
     6481 gatctaggcg gcgatgtagc aaaagtattt cgatgtccac ctgtgccgct agatcaatac
     6541 aaactttgac acgagaatcc aatgctgtca cccaccagct taataagcct cccatagaaa
     6601 gaccaatcgt tgcgagccgt tgagtatctg tgtcttccct tgtctccaaa taatcgatca
     6661 agctgatcac atcataaata cgcattcccc ataacgtttt tcctgttaat aaaaattgtt
     6721 tgaacaactc gctttcagaa atacctccgc gttcttcaaa tccccaagca tcaatcgacc
     6781 aaacagcata tcccattcct gtcagtactt ctgcaaaaga tggagaagct aagtaaggag
     6841 caccatggat caattcactt ttcccgactg aaaaatctcc gccgtgagaa tgcaggtaaa
     6901 ggaccggcgg aaacggtcct tctttttctg gataagcata gagggctggt actgtttcca
     6961 attcatttaa gtacaattga tagtattcaa gcataaaacc gttttgtttt tctcggtata
     7021 atcgttttcc actaggggta tgtctgctag atggagcacc taaaaaatca ttcaactgca
     7081 taagcaaagt ttttacgaac aaccagttca tccatatttt ctgattgatt tgattggaat
     7141 ttctcaatac tgatttcttt agtattttct aatagaaatg ctggtccctc gtgattttca
     7201 atcgacatct ggttaaagga aaccttaccc gcaaagccaa tataaaatcc ttgtctgctc
     7261 atttcctcta ttcctgtcat catagcagga acaccgggaa ctgcatcttg ggccatcgag
     7321 acatcgatat tgtcaaatgt gatttcttgt atgaattgtt ccgctaatcc ataaataaaa
     7381 cctgcagaag catggacatt ccttgccgtg atattcgaaa aatggatcct tctgaatgct
     7441 ggtgtccgtt catctatcgg ataagccttt ttttcccata catacggttc tttccctcgc
     7501 ggaccacaga aataataaag attcagtata aatggacaca tcacattatc catgactata
     7561 ttggatactc gaatatcttc aacgatcccg cctcgacctc gtctagattt caatcgtatt
     7621 cctcgatcag tttcttggaa gatacaattt gaaatggtaa tattacgaat actaccactc
     7681 atttcacttc ctaatacgac accgccatgt ccatggacca tcgtgcaatt tgtgatcgtg
     7741 atattttcgc aagcgatcct ttcgtacgta tcttcagtcc ctgccttgat tgcaatacag
     7801 tcatctccca cgtcaatatg gcaattacta atacgcacat ttttgcatga ttctggatca
     7861 attccgtctg tatttggtga atccgctggg ttcaagatcg tcaagttatc aaacgttgca
     7921 ttactgcaaa gaatcgggtt gatcgtccaa cttggtgact ggatcaattt aatatctttc
     7981 acagtaattc gatgacagtt atggaaactc atcaatttag gacgaggata agcgagatta
     8041 tctggttcat ttctaaaagt atgccaccat ttttttccat ttccatctaa tgtaccgaaa
     8101 ccagtgacag agatgttctc tacattttga gcatagatac aggaagcata aacttttcga
     8161 tggactcctt cccaacgtga atgaacaaca ggataatctt ttggatcgtc agagaatttc
     8221 agaaccgctc ctgcgcttaa atgaagttcg acattgcttt ttaaaaataa agctcctgtt
     8281 agaaattcac ctgctggaac aactacggtc ccgcctccgt cacttgctgc agcatcaatg
     8341 gcttgttgta ttgcttcagt attcaattca tcaattgatg cgccaaatgt caaaatatca
     8401 tacatattta taatgcctcc acttcaatca atgcttgcaa gaatgcacca acgccttttt
     8461 gatcattaca aataattggt tcactgatgt agtaagcata tgaaccatct cgctgatctg
     8521 ctccgcctaa ccctgctact tgacagtttt tattcaagtt cagccagcct tcttttgttt
     8581 ccagaacaaa ttcatcaagt aatccttgat gtgatttctt cacttgtgga agccattctt
     8641 ctttgttcag cagtcccaaa cgtattcctt tagccattgc gtaaacaaac atactactgc
     8701 cggaagcttc cagataattt cctttccgtt ttgtttctgt tgttacttga taccatgtcc
     8761 cgctgttttc ttcttgatat ggaagtaatg cagccagtgt cttttctaga atttctttca
     8821 gcaaagaaca atctgtttct tcatgaagta attcataggt atctgctgca gccatcaaat
     8881 accagccaat cgatcggctc caaaaatgat gggatagacc tgtttttgga tcagcccatg
     8941 gttggacctt cttttcatcc catgcatgaa tcagcaaatt tgtttttgga tcgaatagat
     9001 gtttataact gatttcaaac tgtctcaaaa catcttggta atctttttct tcactaaaat
     9061 tctggataaa ttcagcataa aaaggagaac ccatatataa gccatccaac caaatttgat
     9121 aaggataaat ttctttatgc caaaaagctc cttcggatgt gcgtggatgg tttgccaact
     9181 gctgggaaag gagttctgct gcttttttat atttttcttc gcctgtttct ttgtacaata
     9241 aaaagaaaag ctttcctgta tttacatggt cgatattgta ttcttcaacg ctgtagccac
     9301 ggatcgttcc atcttcttgc acgaaatagt cgatattgtc ttttatgaaa tcaaaataaa
     9361 ttttttcttg ggttcgttcc caaagtaatt ggaacccttt aagtacgacg ccatagtcat
     9421 aagaccattt tcctttatac cacttttctt catataagcg aggtgttctt tccatgatac
     9481 tttttgctaa tttctttgac cagttttcca ttatttgctc tcctttaaaa attaaaatag
     9541 gatttgggac aaataccaag aagtatttgt cccaatcgtc tatattactg tgccgctgct
     9601 ttgtatgctt cctcgtactc ttgtgtgatt cgatcgcctc cttgtgcttt ccagtcttct
     9661 acagcttttt tgaatccatc ttcgtcaagc tgtcccatga tgtattgcac cgtagcatca
     9721 atgacgattt tttcaatttc tgatcctact tcattgttcg tcggtgaatc caatggcaca
     9781 gaaggatcca ttacagcaaa ttcttcattt tctttgatca attgattaga gaattctttt
     9841 tcagggtctg tatctttgaa agagaacgtc acttcactag gacgagagct tgataacggt
     9901 tgcacctctt gttgccaaag atccatatcg ataaattcga tagaaccatc atcattcaat
     9961 tcataatgcg ttccttcgat accgccagtc atcaatttat acacatcttc ttctaaaaga
    10021 tcatcaacaa attgaagtaa tttcttcaat tgtgcttcgt cttttacttg agatttggga
    10081 aatgctagca agccgccaat accatttcct tctgaccaaa catgataacc gccgccttca
    10141 ccatctgaga tcttgtttac aggcactaat tccatatcat cttgaatacc ttgacccatc
    10201 gtcttcagat tcttgatatc caccattcca gtgtagattc cagttcttcc ttgtgcaaat
    10261 tgttcttgct gatcagtctt ttgggtaact gcaaagtctt gtgccaaata gccattctca
    10321 aatagatctc ttgaaaaatt caaagctttc atatactctt ctgtatcaaa ttctggagtg
    10381 aatttgccat tatcgtctac agcccagcca tttggtgctc caaaataaga agtgaaaagt
    10441 ttaaagctgg tataacgaat atcactaggc gcacgatcgc caaaaccaac tgtgtcgtcc
    10501 acaccatttc catcaggatc gttttctgta aattgtttag ctacttcata aagctcatcc
    10561 atggtagttg gaacatctag tcctagatta tccaaccagt cttttcgaat gactaagcca
    10621 gcacgagcgt agtctttttg tatcggtacg ccgtacaagg caccgtcgat actcgcagct
    10681 tcgattctat cttcagaaat ttgacttaaa tttttatagt cttttaaata ttctgataca
    10741 tcccagaata cgcctgattt taacgcattg cggacagaag agtttttcaa catcgcaatt
    10801 tgaagtgtaa cgatatctcc tagttcatca gaagccaatg cagttgttaa tctttcttct
    10861 tttgaagcat caggaatcca gttgaatgtc agttccgtat cggttttttc ttcgatcaag
    10921 ttcacaatcg tgtctgtagg cggtgaagca tgatgcaaaa tatttaacca agtgatttta
    10981 gcttttccat cttctgtctc tgaagaactg ttacttgaac tgctgccgca tgcggcaagt
    11041 gctagaattc ctgcaaaact aagacctaat tttacgagcg ttgctttttt cataaatttt
    11101 ctccttcact gttttaataa tatttttgtt ttcttctgtt ttttctgtat atgagttctt
    11161 ccattccaaa tggcaaaata tagaatttgc tgtccacgtg actgcggaaa agaagagact
    11221 gccaccgata aaggttaaaa cacctggcat tgtttggatg atcatcagat aaatccctac
    11281 catacttaat atcaacacta atgagtaatg aagatgtgag aatccgaata aaaatgccat
    11341 tttcattttg aaaaaatatc ctttccaatc ataatgagcc atgattggga aaatatagag
    11401 tgctgagagc acatatatga acgcagcaat atacaaagcg atcctaagat accaattgtg
    11461 tatgaaagaa agatccacaa gtaaaacaat cccgatggcg ccatatatcc agctcatcag
    11521 caaggtttca cgatagtttt ctttaaaata tgtgaagtac gttttcgtca aaggaaacgt
    11581 ttcttttgag cgcagccatt ttctaatcac tgcaaccatc gcatacgatg caggaccgaa
    11641 agtaaaaact cccaaacctg cgatgactaa accgccccac agaaaattca aataaaccaa
    11701 ctgtaaaata cgatttagcc ttccgtttat tttatctaat gactgcagca tatctttccc
    11761 tctctttcta tcttagtaaa cgccgtcttc tcctagcttt ttggcaatct tattagctaa
    11821 aattaccata aacaatccta cgaccccttt aaacaatccc attgctgtac tgaaacttaa
    11881 ctgtccattc ttcaatccag ctgtataaat ataggtgtcg aaaatttctg caacgcttcg
    11941 attcaatgaa ttcaataaca agtacatatg ctcgaaccct aagtctaatg tctgaccgat
    12001 ttttagaatc agcaaggtaa tgattactgg acgaattgcc ggcaatgtaa catgccatgt
    12061 tttgcgtaag cgtcctgctc catccatttc tgcagcttca tacaactgtg tatcgactgc
    12121 agttatcgct gaaaggtaga tgatcgtaga ccagcccaac tctttccaga tcacttgtcc
    12181 gatatatact gtgcgtgtcc attcagggga tgttagaaaa ctgatttttt caaatcccat
    12241 tgttgcaagg aattcattca atacccctcc gtcaacattc aaaaatacat aagtaatcga
    12301 aacaatgatt acccaagaca tgaagtgagg gatgtaaatg atcgtttgaa tcccgttttt
    12361 caatcgtttg ttcgttactt catttaatag taaagacaaa atgattggca tcggaaaaaa
    12421 cacgaagata tttaatccga acaagatcaa cgtatttctt aataatgtaa agaatgtcgg
    12481 ttctgtaaac aaacgaatga aatgtttgaa accgacccaa ggacttccca ttattcctaa
    12541 aaatggttga taatcttgaa aagcaataac gagtcccccc ataggaagat acctaaaaat
    12601 caagaaataa aggactcccg gcagaatcat cacatataaa aatttattcg ttttgattcc
    12661 tgcaattatt ttttttcgtc ttctgagctt ttcttctttt ttcgatagcg tcagttgaaa
    12721 tggttcttgt ttctttacac tttccataag cccctcctta gttttgtgaa tgtttgctgc
    12781 ttatgacttc atgatagata actatctgaa ttacgtatat aatcattttt accgtaagta
    12841 aaaacgctta catagcaatg atttttgtgc tatacaaaac gataaagtgt attttttcac
    12901 aaataaacta cgcatagcaa accttctatt tttttctatc tgacacttag cataggaaat
    12961 gattatatac gtaatctttc accgatgata aattgaacat atagaaacag aaacatttaa
    13021 tttattttga ggaggagcct atctatatga aaaagaaagt ctctatagga gaaagaagtt
    13081 ttacactttt caacaatacg tttctaattt tgctagcttt gatctgtatc gttccttttt
    13141 taaatatcat cgctacatct tttgcttcta cacaagaagt cgtcgcgaaa aagtttatcc
    13201 tttttcctac taccttttct ttagacgcgt atcgctacat tctttctacg ccgaccattt
    13261 ttagagcact tgctgtttcg attggtgtta caggtgtcgg aacgatcgtc agtatgtgtg
    13321 caacttcact gatggcctac ggtctttcca gaaagtattt gtttggtcga ggtttcgtca
    13381 actttcttgt tgtattttct atgttgttca gcggggggat gattccaacg ttcttagttg
    13441 ttcgttctct agggctggtc aattcttact gggccatgat cctgcctgtg gctgttaatg
    13501 caatgaatat gatcattatg agaaactttt tccaagcctt gccggatagt ttggaagaat
    13561 cagcaaaaat ggatggttgc acagattttg gtgtattttt caaaattatg ctgccattag
    13621 cgttaccgtc tattgctact atctcgcttt tttatgctgt tacttactgg aacacttata
    13681 tgactgctat tttgtatatc aacgattcat ctaaatggcc gatacagatt cttttacgcc
    13741 aaatcgtcat tgtatcaagt gggatgcaag cagaaagtag tgccgttgat gtgattccac
    13801 cagcacaaac agttaaaatg gctgttatcg ttattgcaac agtgcctatg ctgattgttt
    13861 atccttttgt tcagaaatat tttgtcaaag gagcactcgt aggttctgtc aaagggtgat
    13921 tatgtactga acgcaaaatg gtagttgtgt cagaagtggt cagcttcaag aaataagaag
    13981 gcatttacga aaattgcttc ttaaattttt gtgaaatttc ggcttatttt tcgaagaatc
    14041 tactcctgga acaccgtgta tcagaggttg tgaaagagac gttcagcctt gagcgatgat
    14101 aaaaactctc acaaacattg cgacgagtaa cccacaggag caataagaag cgattttgaa
    14161 aaatagcttc ccatatttca caaaattatg ccttattgtc gatagcctgt ctcttgaacg
    14221 ccatttattc gtaaaaaaga actgtgacaa gacttttgtc acagttcttt ttgcgtgctt
    14281 agccttgaaa tttaactatc cataaataca aatactaggg ttattctaac ttcttttatt
    14341 gcttgaatca gtccacaaga aaaacagcct cttgattcac aaatattttt ttcgatattc
    14401 tcccggcgta atcgattcct tctttttaaa gaaacgaata aaattttgcg gatttcgata
    14461 ttgcaatctt tctgcaatct cttttacgga gaggttagtc tctttcaacc atttttttgc
    14521 tacctctaaa cgatgatttt gaacaaaatc accaaatttt tctcctgttt cctttttaaa
    14581 tacattactt aaatagttag ggttataatg caacctatca gcgatcacat ctaaagacag
    14641 atcacgatca tattctgtgt agacgatatg cataatattc tccgacaaat ttttaaattc
    14701 atgatcagtg attgcttgag agcattctgt gattggcaga actaattgtt ctaaaacaag
    14761 tttttctagt tctttgggat gataattgtt cagtgctttt acataaattt gtttcatgtt
    14821 atcaaagttt tttgaatcta ctcccaataa ctgtcctaat tgaacgagtt cattgatcaa
    14881 gcggaccgaa actacttccc gactcaaagg atttttattt tgtgcaaaca atgcatcaat
    14941 caattcatgt actaaattct tcacttcctg atttccagaa cgaatggctt caaacaatcg
    15001 attttgttct tctatcggat atctaataag tgttttttca tgagcagcag gaacgatttc
    15061 ctgataaaaa ataattgaac ttggaccagt atttacacga taatacaggg cttcttttgc
    15121 ccgatcaacc gattgcttgc tttcattcag cgtttcgaac cggttactga tgcctatact
    15181 gatagttaaa ttcaagtatt cttttacacg tttttgaatg agtcggcaat actccatgac
    15241 ttttttgctt gcttctgcat catctttatc cattcgataa atagtggctt gcatttcttc
    15301 attcaaaacg atcggcagca ttcgattttc ctttggcaca atttccgtga tcatgttgtt
    15361 gatcgctaaa agtagcaaat cacgctcccc accgtgacta tcttctaaca gatcgatttg
    15421 aaccaaagct gtataatagc agtcattttg agaactataa ccaaattgct gcaaccgctg
    15481 atctagttct cgcctttcta ctcgatttct aaataaacta agtacaaata gcgtttccag
    15541 ctgtggcttt tgggtaacta agtgtgcact taacgcttct ttttctccta tgatccgact
    15601 gactgattga gcgaccaaat ctagttcttt cccactgaat ccttttgatt taagattcag
    15661 acgttcctgt atttgagaaa tcggacgggc aaatctgtcc gaaaataagt aggaaagaag
    15721 accaatgagt cctaccagtg ttaaagacac tgcaactagc ccgattctca gattgcggat
    15781 cattgcgcca attgcactag agtcaacttc taatctgtaa atccaattat tataatctga
    15841 tttcagtact atatacgttt tatctttttc tcttatcact ttcagctgat tgtaatctag
    15901 atccacgtcc gttaatacag ttggttgctc tttatttttt actgtctgag tagtaaaaag
    15961 gttgccaact tcgttttcaa tagaaagtat gtcttctcca ctttcaccaa caacttgttc
    16021 tattgtatgt ttctctatcg tagcaattcc caatgcatat ttttcttttt caaacattgg
    16081 caaagaaatc accatttcga ttcctttgtt tttcttttgc caaaataaat tatttttgtt
    16141 atttatgtac ttctgttgat acttttcaat ttcctcttcg gtcagttgac tcaacgatcc
    16201 attgattact ccccatttac cagccaaact gactaaatca taattattat catccataac
    16261 aatcgtttct ataaaattta gttctttcct gatttcagaa taagtggagt aatctgtata
    16321 tgtcagcgga tgcttgaata tgtccgagaa atttttggtc gaaccatacg tagaaaacga
    16381 atattcaatc gttctaattt tccattcaac gttagtttta acttgcctga gcaaattctt
    16441 tttgtctgtt aaataactcg attcgatcga ttcataggta ttctggtaaa tgaataaact
    16501 aaatcctatg acaagtacgg ctcctaataa aaacatcggt aaaaatattt tataaaatac
    16561 tgtacttttc ttcattttct tcctctcctc cttttaaaat aaaaggcttt catttttctg
    16621 taaaattgat actcatctaa ttaaatgagc attccccgct ttcaagaata gcataattaa
    16681 aaataaaaat ccaagtaatt tttaacgtgt gcaatctttt catatcaaag atctattgac
    16741 ttatcgtagt tatcgtaata tgatgaatgc gttaacaaaa agtgaaaaag taaggaaaat
    16801 gatggaatgg taacgatcaa agatgtcgct aaagcagctg gcgtttctca tacgacagtt
    16861 tctcgtgctt tgaataacag cagtttaata aaaaatgaaa caaaacaaaa aatacgacaa
    16921 ctagctaagg aaatgaatta ttcgccaaac tatagtgcaa aaggtttagt gaatcaaaaa
    16981 aaatatctaa tcggactatt tttctcaagt ttgcataaag gaacttcatc aaatttccta
    17041 gcagattcca ttgcaggcat ccattcagta ttagacacaa attacagttt atctgttgaa
    17101 agtatcgatg ttgttgattt aacagaaatc aacctgcaac gctacgatgg actgatcgtt
    17161 atgagtcaaa gtgatgatga tcagcctttc atcgactatc tcaaagaaaa agaatttcct
    17221 ttcgttgttg tcaatcgtca catcaatgat ccagcggtta tcaacgtcac tgccgatgat
    17281 gcggccggtg ttatgcaggc agtagattac ggtattggat gcggacatac gaagatcgct
    17341 tatattggcg gaaagaaaaa ttttcgttcg acaaaagaac gggaaaaagg ggtattgaaa
    17401 agtctaaaaa aagcgagcat ccctgtcaat ccagcctatt ttttaacagg agattacagc
    17461 ttagaaagcg gcctccaaaa catggaatac ctattatcac tttctgacct gcctactctg
    17521 gttttttgcg gcaacgacga catagcgatt ggtgcattga gagctgtaca tttagctggc
    17581 ctccgtgttc cccagaacat ttctctgatc gggttcgatg attctccagt cgtctcctat
    17641 ctcaatccgc cgcttaccac cgtacgtaag cctttgaaag aaatgtgtca agaaggaaca
    17701 aagcttttac tagatttgat cgaaggcagg acgatcgaac aatctaaaat tgagctctcc
    17761 accttgttga tccttcgtga gtcgatcaat tacttgtaaa ctacaagtaa ttttatataa
    17821 aaatgttaac gtgtgcataa cacagaaagg aagtttatat gaaaaaactg acaaaagaat
    17881 tagtgaaaaa aaacgaagca cctgtaaaag ttcttcagtt tggtgaaggc aattttatgc
    17941 gtggatttat tgattggcag attcagcagc tgaataacca acaattgttt aaaggtaatg
    18001 ttgcaatcat tcaaccttta gaacaaggtc ttggaaatat gatgaaccag caagataatt
    18061 tatatacggt cattttacaa ggactcagca atggcgaaat cgttgatact tccgagatta
    18121 tcaccgtagt agaacaaatg atcaatcctt atgatgaatg ggatgcttat ctatctctag
    18181 cagaaaatga cgacttggcc tatatcgtct ccaatacaac agaggcagga atccaattcg
    18241 tggagactga taatttaaca gatactcccc cacagagcct cccgggcaaa ctgacagcct
    18301 ttttataccg acgtttcaaa ttaaacaaag ctggctttac catcattcct tgcgaactga
    18361 ttgacagaaa cggcgaacgt ctaaaagaaa tcattttacg ctacgcagaa aaatgggatt
    18421 tagaacctgc ttttgttgag tggttagaaa aagaaaatgt tttctgttgt agtttagttg
    18481 atcgcatcgt cccaggttat cctcgcgaag atgcaggtgt tttcaatcaa cggcataact
    18541 atgaagatca attgatggtc aaagcagaac cattcatgct ttgggtgatc gaagggccta
    18601 aagaattgga gaatcaacta ccattcaaac aggctggctt gaatgtcatc atcacagatg
    18661 atatgactcc ttatcgtgaa cgtaaggtgc atttgcttaa tggaccgcat acagcgatgg
    18721 tccctcttgc tttgttggcg gaattggaaa ctgtagaaga agtaatgaaa gatcctttat
    18781 tctccgcata tgttgatcag ttattcaatc tagaattgat tcctatgctt tctttaccta
    18841 aagatgaatt agccatttat gctgaccaaa tcaaagaacg tttcttgaat ccttttgccc
    18901 atcacaaatt agaagcgatt tcattaaata gtgtttcaaa gttcagcacc cgtctgcttc
    18961 cagtgttcaa gaagtatatc gaagaacaaa atcaggtacc accgttaatc actgtttcac
    19021 tagctgcgct acttcttatg tatcgaggcg atcaagtaaa gccacatgat gatgaaaaga
    19081 cgataagcga atttactgat gcttggtctg ataatggaac agctattcct cgattattgc
    19141 aaaacgctgc gctttgggga gaagatttgt ctcaaatacc gaatgtgaca gatacagttc
    19201 aagaaatagc tgcaaagatc gatcaaaaag gtgtccggtc agtattacaa gaaatgaaag
    19261 gaacgatggt ccatgcttga aaccctgcaa ccaacaatga aattaaatcg acgagacagt
    19321 gtggtcgtcg cattaacccc tattccaaaa caaacacaac tgacgattga tcagcaaacg
    19381 atcaccactc ttgaagatat cccgcaaggt cataagattg cattgggtga tttgaaagct
    19441 ggagacaacg tgatcaaata tggctatcca atcggtcatg tgacgacaga cgtaactgcc
    19501 ggtcaatggc tgcacactca taatgtaaaa accaatcttt ctggtgaatt ggattatcga
    19561 tatgaaaaag atgtccatcc aagtcattac ctttttgaga accgaacatt tcaaggttac
    19621 ttgcgaaaaa atggaaaagt agggattcgt aatgatttgt ttttagtacc taccgttggg
    19681 tgtgtgaatg gcattgctga actgatcgtc aaacagttca aggaaaaaca tccagatctg
    19741 ggacagtttg accatattac gattttaaag catccttatg gctgttcgca gcttggaaaa
    19801 gatcatcaaa atactcgaga aattttagcg gacgcagtaa atcatcccaa tgccggagga
    19861 gttttagtat ttggattagg ttgtgagaac aatacagttc ctgaattcaa aaaaatttta
    19921 ggtgaatatg atgaagaacg agtgaaattt ctagtggctc aagatgttta cgatgagatc
    19981 gaacaaggtg tggctctatt agaagagctt ttaacagcgg cggaaaatga ccagcgcata
    20041 tcagtcccgc tctctaagtt gaatgtcggt ttgaaatgcg gcggttctga tggtctatcg
    20101 ggaataactg ctaatccttt acttggtgca ttttctgact acttgattgc tcaaggaggc
    20161 agcacgatct taacagaagt gccagaaatg tttggcgcag aacaagtatt gatggcacga
    20221 gcggaaaatg aagaagtttt tgactcaatc gttgacttga tcaatgactt caaacagtat
    20281 ttcttgtctt acggggaacc agtttacgaa aacccatctc ctggtaataa agcaggtggg
    20341 atcactacat tagaagataa gtctttaggc tgcacgcaaa aatcaggaag ctctcctgtc
    20401 gttgatgtgc tacaatatgg cgaaaaaatc agaaaaccag ggcttagttt attgcaagct
    20461 cccgggaatg atcttgtagc tgcctctgct cttgcttcat ccgattgcca gttggtcttg
    20521 tttaccacag gaagagggac tccgtttggc tcatatgtcc caacggtcaa ggtatctacg
    20581 aatacaactc tttttgaacg caaaggtcat tggatggatt ttaatgcagg cgtcttatta
    20641 gaacaaccaa tggaagtaat cttagaatcg tttgttcaaa aaatcatcgc tgtagctagt
    20701 ggagaagaaa cgaaaaatga acaaaatgac gttcgagaaa ttgccatttt taaaaacgga
    20761 gtaacacttt gattttcata aaacagtata aaaagaaaga aggaagattt atgtttttat
    20821 ctgatgattt tttattaaaa gacgattggg cgaaaaagct ttaccattcc tacgcaaaaa
    20881 acatgcccat tattgattat cactgtcact tagatccaaa agaaatttac gaaaacaaca
    20941 atttcagcaa tctgacagaa gcttggttag gaggcgatca ttacaaatgg cgcttgatgc
    21001 gagcttgcgg cgtgcctgaa gaaaaaatca caggaaatgc ttctgatttt gaaaaatttt
    21061 tagcttggtg tcaaaccgta ccaaaaatta tcggaaatcc gctttacagt tggtcacatc
    21121 ttgaattgaa gcgtttcttc ggtattgact tgttgataaa tgaagaaaat gcagagaaaa
    21181 tttggacaca agcaaatgaa attttggcag ctcctgattt tcgccgtcgg gaaatcgcaa
    21241 aaaaatcgaa tgtagaagtg atttgtacaa cagatgatcc cgcagacgac ttgcactatc
    21301 atcagttgct tgctcatgaa gaaccagatt tgaaggttct accttcattc cgtccagata
    21361 aagcactcaa tattgaaaaa gaaggattta atgcatgggt cacactactg gaagaagcag
    21421 ctgaccaaac gatcaccacc tatcaagaac tgatagaagt cttagggcag cggatagaat
    21481 acttccatca acatggatgt cgtgtttccg accacgcttt agacatctta cgctataaag
    21541 aagcggatga aacagtatta gaagagattt ttcaaaaagc acgagctaac aaactattat
    21601 cttcagatga aatcgatgct tatcgtacag aaacactgat acatttgacc cacttctatc
    21661 attctcataa ttggacgatg cagctgcaca tccatgctta tcgtaactgt aatacacaaa
    21721 tgttggaaaa attagggccc gataccggct atgatggaat gaatgatctt tctttgacta
    21781 ttcctctgca aaaattattg aaccgtgcag aagaaacgga tcagttgcca aagacgatcc
    21841 tttattcatt gaatccgaat gactatcctg cgattttagc tttgatgggc tgtttccaaa
    21901 aagaacagaa tggaaaactg cagttaggtt ctggatggtg gtacaacgat actcgagctg
    21961 gtatgcgcga tcaattgaca caatttgctg atggtagtgc tttggggaat tttgtcggca
    22021 tgctgacaga ttcaagaagt ttcctgtcct acactagaca tgaatatttc cgtcgtgttc
    22081 tttgtgaatt tttaggcgaa atggtcatgc gaggagaagc acctgaagat gaacaacttt
    22141 taggaagtct agttcaagcg attagttata caaatgctaa aaattacttt ggcttttttg
    22201 cctaattgat taatagtaac agtaacgaat caaaaacagg atagtgaaat aacggaatcc
    22261 gtttatccac gttttagaga agaagacgga ccaaatttgc tccgtcttct tctcttgctg
    22321 ttctgcttca ttgcctataa acctttatga aagaagagat aacatgccta ctatccatat
    22381 tgccggtgat tctactgcgg cagaaaaaga tgaaaacaag cgtcccgaga caggttgggg
    22441 agaaaaaatc tctgcttatt tttcacccga gatccagatc aataaccaag caaagaatgg
    22501 acgcagcacc aaatcattta tccaggaagg aaggttagcc cgtctagctt cacagtttca
    22561 gccgaatgat ttcttatttg tacaatttgg acataacgac cagaaaatcc aagaagaaag
    22621 aggtacgctt cccttcggta gctatttaaa aaatctgcag atattttttg aatgcgcaaa
    22681 aaaagcgaac gtccaaatgg tcttactgac atctgtgacg cgacgagatt acttagaaaa
    22741 cggaacattg aatccagata tacttggaga ctatccaaaa gcgatgcgtg catttgctga
    22801 gaaacaccat attcctcttt tagatgtgtt ctcaagatca caagaattgt tccagacctt
    22861 ctcaaaagaa gagacaaaaa aattctacct gcatcttata cctgatactt gtaaaaatta
    22921 cccagaagga ctaaaagaca atacccactt tagtccagaa ggcgctgata aagttgcccg
    22981 aataattgtt gaattgataa aagaatcccg tctgcctctt gctaattatt tacaaaaagg
    23041 agtttgagat gtttccatta aatttaggca tccgtgccca cgatttagat gttcgaaatc
    23101 gtgaagaaat cgttcaaaaa gtatcacagc ttcacttgtc ccatatccaa tttgcaccac
    23161 aaaaagcatt tcctgaacaa cttaaattaa ctgacatgac acttgggagt gctgcctatt
    23221 ttggtgaata cttccaaaaa aacaatatcg aactttccat tttaggatgc tatatcaacc
    23281 tatccagcaa aaatcaagaa gttcgtgcac aagcattggc aactttcaaa cagcaaattg
    23341 ctctgtgctc tgcctatcaa gccaagatga ttgctacgga aaccggtagt gtctctgtcg
    23401 gttacacaaa agaaaatttt actgaagaag cttatcatat cgccagaaat tctatcattg
    23461 aattagtcgc tcatgcagaa aattttggcg taactgttgc tgttgaagca gggatcaatc
    23521 atccaatcta taactatcag ttagctaaac gtttaatcga tgaagtagct tcaccaaatt
    23581 taaaaatcat tttagattgt gcgaatttga tgcataaaga aaatcatgct gatcaggaaa
    23641 aagtgatccg aggtgccttg gacaatttac atggttatat tacagcgctt catctcaaag
    23701 actatatcat ggaaaatgga aagatccgca tggtacctgt tggcaagggc tgtttagatt
    23761 tccgcccggt actgcattat atcaaatatg agcgtcctct aatgtacgcc actcttgaag
    23821 ctactcctga gatttatgtt cctgaagcaa tagaacactt gcagtttatt taccaagatt
    23881 gttaaggaga agattatgga ggaacgaata cagaaaagtt atcaaaaata tcatgcaaat
    23941 gcttttcaga cattgctgca tctttatcag ggaaattatt ggcgttttgc catgtcagga
    24001 ctctttttta ttatcaaaca tcttccatct tggttaatgc cgatcgctat tgccaatgta
    24061 atcaatgcag cttcatcgaa agattcttct cagttgcagg ccatttattt caacgctttt
    24121 ttgatggctt gtctgattgg tcaaaatata ttgacgaatt attttcatgt aaaataccat
    24181 agcacttcga tccgtcaagt agaagctgga ctaagagcga cccttatcaa gaaaatccaa
    24241 gaactatcta ttccttatca aaaagaattg caatctggac gaatccagtc aaagatcatc
    24301 cgtgatgtag aagctatcca aacgttgtcc tctcaagtat ttgtcagcgg attaaatatc
    24361 gctgtcaatt tattcgtagc tttaggtatc acgctttata aaagtcctgt tgttttcatg
    24421 tttttcttat tgactgttcc tctcgccgca ttcgttactc tctttttccg taaaaggatc
    24481 agacagtcca actcagactt caggcaagaa atggaagaga cttctgcaaa agtgatcgaa
    24541 gtgatcgaat tagcaccgat tgctcgagct catgggttag aaaaacacga aacaactcgc
    24601 ttaaataagc attttactca aatctatgaa aaaggattcc acttagatat cctgcaatct
    24661 gttttcggat cagtcagctg ggctagtttt cagatatttc agctgatttg tttgattttc
    24721 actgggatat tagctttaca agggcgcatc caacccggcg atgtcgtgat gtatcagacg
    24781 tatttcacga cgatcgtcaa ttccgtttct ggaatgatca cgctgattcc tacgatttca
    24841 aaaggcatgg aatctatcac ttctattggc gaactgttga ttgctggcga tgtagaaact
    24901 tatcacggta agaaaaaaat ccaacatttg gatggaaatt ttcgttttga ggatgtttct
    24961 tttctttatc cggactcact caaaccgatt atcgatcatt tttctctaga ggtgaaagct
    25021 ggagaaacaa ttgcttttgt tgggccatct ggctctggaa aatctacact ccttaactta
    25081 ttgattggat ttatccagcc gacttcagga aaaatttttc tagatgatca gcctttggat
    25141 gaactggata tgcgaagtgt gcgaaattat ttagccgttg ttcctcaaac cactttgttg
    25201 ttctccgctt cgatcaaaga gaacatcact tatggcttga aaaacgtatc aaaagaacgt
    25261 ttagatgaag tcatcgaagc tgcgcaactt tcttcactga ttgaccagct tcctgatggt
    25321 ctggatacct tagtaggcga acatggcaac aagctgtctg gtggccaaaa gcaacgtatc
    25381 tccattgcac gagcgttgat acgtcagcca aaaatcattt tgctagatga agcaacctca
    25441 gctttagata accagtcaga gaaaaaaatc cagcaagccc tgaattacct gacagaaaca
    25501 cccactactt ttattgtggc tcatcggctt tcaacgatca aagaggcaga taaaatcgtt
    25561 gtgatcgatg aaggaaaaat cgttgaaata ggtacttacg aaaaactgtt agctcaaaaa
    25621 ggctatttct accgcttgaa aaatgaatga caaaaaatag gagctatgac aagacttttg
    25681 tcgtagctcc tatttctgaa taaacggtgt tctcctgcca actcctcggt cacaagtcac
    25741 aatagtcatc aaacatgaga agctgttttt tgaaattgtt ccttgtaact cagagttaaa
    25801 cggtaggctc acgacctctt ggtaaatggt gttcaagaga cagcctatcg gcaataagaa
    25861 gcaattttgt catcgctcaa ggccgaacgt ctctttcaca ccctctgttg tttcataaaa
    25921 tagttttatt cgctgtaaag gtcgcgaact ggtgtcatga tgatacggtt caagtcattg
    25981 atgattgtac tgaagccttg ctctttttgc atcaagtcat tgattacttc ttctgattgg
    26041 attttcacag ccatttcttg tgctttcatt gcatcttcgt cgctgaactc ttgtccactc
    26101 atttgttttt cttgtaattc gatttgcatc gcttggaagt ctttgaacag tttgtgtgct
    26161 tcttcgtttg cttgtacttt ctcgtacgct tctttcaacg ctttgaattc tggtaattca
    26221 cggatctcac gttcgatttg attcgcgcta tcgtagatgt ttgacatgtt atgccctctt
    26281 ttcttttagt agttactctc tattgtaaca tggggttatt cgttttcaaa ggggctactc
    26341 tccttgatat ttccgccaga ggtctttagc cgcttcacca attccctgaa cgccttcttt
    26401 caccatatcg ccgaagtttt tcagcccttc ttttgcttgt tcaccatatt gattcaagtt
    26461 atcttgccaa tttccagact ctccattaga atttcctgtg tttccaactt gatctgcagc
    26521 taccacttgt cctcctgtgg cataggcatc tgctacacta aatcctgttt ttgaagtata
    26581 cggaaggatg ccttctgccg ctgatttgaa gactttcccg acaacatttc cacttgtccc
    26641 ttccaaatag tgcagcttgc tggattcttc gtaacccatc catgtcgaaa tcactacgtc
    26701 tggcgtgtaa ccgatcatcc attggtcatt tgcttttgtg gcatcgaaat tagtttctgt
    26761 ggttcctgtt ttccctgcta tcgtataacc tgcaggattc gcagcagccg ctgttccatt
    26821 tgaaaatgta ccaagaagca tgctggtcat ttcatcggct gtttcctttg atatgacctg
    26881 ttttggtttt ttgtttgtgt tatcgacgat caccgctcca gtcgaatcaa cgattttcgt
    26941 gataagatgc ggcgtataca tctgaccatc attggcaaat gcactgtaag cacccgccat
    27001 gatcaatgga gatactcctt tttccagtcc accaagggct aagccataat acttatcaga
    27061 ttttgctaaa ggcaggccga attcttctgc tttatcatat cctttttgta aaccgatctc
    27121 atgcaaaagc catacagtag gcaaattcaa actttgtgca acagcttgat acatcggtac
    27181 ttctccttgg tatgtcccgt caaaattatg cgcatcgtaa taactttgcg gttcgtcttt
    27241 caagatactg gaaggcttgt atccagcttc cagtgctggt gtatatacgc ttaatggttt
    27301 gatcgttgat cctggtgaac gacgcatctg tgtagcaaag ctgaatcctc taaagacatg
    27361 atctcctctt cgtcctacta gtgcttgtac accacctgta ttcggatcta aagctactga
    27421 agcagattgg accatggcac catctgaagc atttgctggg aataatgcac tgttttgata
    27481 agtagcttct aattgctttt gataatcctg atctaaagct gtatagattt tatagccttt
    27541 attcatgaca tcttcttcat caagaccata ctcgttaact gcttcatcga tcactgcatc
    27601 aaaataataa ggataacgat aaccagaatc tgaattatcg tatgtgtcat taagatacgc
    27661 gctgatatct gtctggcttt ctgcttgttc ttgttctttt gtgatttttc cgttttcttc
    27721 cattacactt agtactgtgt ttttccgatc attcgcattt tttgggtgat cgatcggatt
    27781 ataaatacca ggacctttca gcattcctgc caaagtagca gcctcagaca gcgtaacatt
    27841 cgttgcatct actccaaaat actttctgga agcgtcttgg acaccccata ccccgttgcc
    27901 aaaataggca ttgttaagat acatggtcaa gatttcttct ttgctgtact tcttttcgat
    27961 ctcgattgcc aaaaataatt ccttcgcttt tcgatcaaac gtttggtcta atgtcagata
    28021 cgcatttttg gcaagctgct gagtgatcgt acttcctccg ccccctgatg ttccgccaga
    28081 caagaccatt cggactgctg cacgggcaat ccctttgata tcaaacccgt gatgctcgta
    28141 aaaattccta tcttctgtcg agattactgc atcttggata tagggagaaa tcgcgtttaa
    28201 ttctacatat gttccttttt gggcgtacag tgtgccagct tcttcgtttt tcttatcata
    28261 aatgactgtc gattggctta atcctgattt taacgtttcg acatttgctt gttttgctaa
    28321 aataaagagg tagatacttg tcactaagac acagatcaaa ccaatcagca aaatcaattt
    28381 gttcacatga tattttttcc agatgcgctt tcgccatcga tggaattgtc cgagatatgg
    28441 tctgatccaa cgccaaaaac tgatcaaagc agcttttatc ttttctaaaa tgctttgaaa
    28501 atccatttgc ttcttctcct gtctatttga ttcaatcgtc ttattttacc atagtgaaag
    28561 agtgttttct tcctgcttaa gttgtagttc aatatgtttt tttacgttag tgcaagtaga
    28621 gtaacataag aatgaacaga aaaatgtaag ttttttctta aatatgtttt aaaaatggta
    28681 caattagtct gcgattgcac tgaaaggagt acacttgtga aaatcacgat cactttacct
    28741 atgaaccatc ctgaaacaac aattcgcgac ttgcttgaaa aggaatggtt agttcctaga
    28801 aaggttcgac actttttgcg tatacgtaaa aacgtttgga tcaatcaaca acctgctttg
    28861 ttccatcatg aagtaaaggg caatgaccag atcacattgt tattcgaaga aacagattat
    28921 aattatcaag aagttcaatt aggagatgcg aagcacatcc gtgttttata tgaagatgag
    28981 catttgatta tagtggataa gcctgcagga atgaagactc atccaaatga accgacagaa
    29041 aacagtacct tactcaatca tttagctgct tatctcgaca ctaaacagca acgaccttac
    29101 gttgtccacc gcttggacaa agaaacaagc ggtgccgttt tatttgcaaa aaatccattt
    29161 gtcttgccga tacttggaag aatgttggaa caaaaaatga tctatcggag atatcaagcc
    29221 atcgtatggg gagaaattgc caaagatatg accatcacca ataaaattgg acgagatcgc
    29281 catgatcgga gaaaaagggt cgtagatgat aaaaatggtc agagcgcctt gacacatgtc
    29341 actgtcaaca aagtactttc tgaacaaaca caagtctatt gtgttttgga aaccggacgt
    29401 acacaccaga tcagagttca tttagctcat aagggacatc cgatcgttgg agaccctctc
    29461 taccaaaata gaacagctga acgactgatg ctccatgcat tagaactgca catgatccat
    29521 ccatttactc aagaaaaaat agtcggtaaa gctttacctg gattatggga atagaaataa
    29581 aaaagaacag agtcttatca gcagataatg ataagactct gttctttttg tgtaatttgt
    29641 ctgcttactt ttgatgttcg tgttctgcta acagcaaact accgataatc ccactttcat
    29701 tcggcagtcc ccaacgaacg atatattcac ttacttgagg tgtttccata taaccaccca
    29761 tcaattcaac aaattgctga cggatttttt gaaggagatg atcctgattc attaccccac
    29821 cgcctaaaat aatcttttca ggtgctaacg tcaacgtata gttgatcagt gcttgagcaa
    29881 tataataagc ctgaatagcc caaacaggat gatcttgcgg cagatcttgc cctttgatcc
    29941 ctgtgcgtgc ctcaatagac ggtcctgctg ctaatccttc taaacaatct ttatgataag
    30001 gacaagtacc ttcataatgg tcatctggat ggcgtttcac ccaaatatgt cccatttcag
    30061 gatgtgcgat ccctgaaaaa atttcttcat tgatcacgac acctgcaccg attcctgttc
    30121 ccacggtaag gtaaatacaa ctattttttc cttgtgctgc tccttgcttc aattccccat
    30181 atgcagcagc attgacatcc gttgtccaag cagcaggaat attgtagcgt tccttgattg
    30241 tgccaagaaa atcgaattgt gcccaccctt ttttgggagt tgccaaaacg tatccgtaat
    30301 tatcttttgt tttgtcgata ccaatcgggc cgaatgagcc aatcccgatt cccttcaatt
    30361 cataacgatc aaaaaattca aatacctgat ccaatgtttc ttctggtgtt gtggtaggga
    30421 tacttaattt ttctaaaatt tctccaccat ctgaaaccgc acacacaaat tttgttccgc
    30481 ctgcttctat tccgccatac attcgttttc ctcctcgaat ccgattgtcc gaatctcata
    30541 aggttggatt attgggacaa ccgcttgctt cgttggttct tcaagcagat tcaatatgac
    30601 agtttttcca ttgtctttag ttatttccaa tttttctaaa tgactagaca tattgaaacc
    30661 tcttactact actttatcac taaacttgct gcgtttcaaa gctgtaattg caaacgtttc
    30721 actttttatc gttaaatatt gttgttttga aatcaatgtt ccttcatgat gtttgatttg
    30781 ttgagtggaa aaaggaatct gtgctgcgta tgcatgcaaa taagtagaga atttttcttc
    30841 tggtccatgt agttcaatgc tgtaattgaa ccgatgctca cctagacact gtgcttctgg
    30901 tgttggaaaa tatccccaat cgcctagttc tcccacactg cgaagtagcg tcactgcgat
    30961 ttgtccgtct tctgttactt catattcatt caaaccaaag tttccgactg ttacaccgta
    31021 ctcttcatca tgaatattga caaatgcttg ctgatgttgc ggattcgtgg ggttttccca
    31081 acttttagac acatggtttg ggcgcttcac cacttcaaaa atactatctg cttcgtgatg
    31141 ttccacatgt aactttgtag gaaacaagac acgtaagcga tgatctttca tctgattgtc
    31201 gagagtcgtt tcaaagtcga tttttttact atcttttctg attgtcatga ttgtttttat
    31261 ttgaaggatt cgtttttctt tggatcgttc tgcttttcga taacgaaatt ccacaaccat
    31321 ctgctgttct ttttctaaac gctcgtctgc agaaacaggg atttccattt cctgtagaat
    31381 acttattttt gctatttccg gtgtatctac taatactttt acttcagagt tttctttgtt
    31441 actggatagg attggctgat cacagaaagg ttgtttaaag atatactcat ttcctatatc
    31501 gccgatatct tcaaaaatat gcagattatt caactttcgt ttgtttttgc gatcttccat
    31561 tgtaatggta ccattttttt caatcgtcaa atgtagaggg ccgttttcga tgattcgtcc
    31621 actctgatga atcattgttt ccttttcttc tgctttcgct tccccttcta caagcgcgaa
    31681 tgtttcccaa gaaaatgctg gcatgttttc taatggtaaa gtcactttga tcattcttgc
    31741 catatatggc acacggaaac ggtctttcgg caaatcataa ccaaattgga cagtttcttc
    31801 agataaaata gctggtatag tggccccact ttttgtttct acatgatact tacgtttagg
    31861 caaattttct aactcttgat atagttgttc aggtattcct tcagcgaatc tttttctttc
    31921 taattcgatg gttatttctg cttcaccagt tttatccatt cctgcagtat ttacaatgac
    31981 aaatggaaag ctgtcttttg ggaatccggt cgtatcgatt gctgcggtca gctgttctaa
    32041 ggaatcttgt gcaagatact ttccaacttc atctgctttt tcaaaacgag gtatcatttc
    32101 ccgatggaca gaatcgactg aacaaccgca aatactgtcg tgaggatgat tttgcattaa
    32161 tgtcttccaa gcataatcta attgatcatg gggatagttt ccactaactt cataagccat
    32221 cgtcgcaagt ggttctgtaa tattttctag ctgtcgctgg accttggtat tccattgttt
    32281 taagtaaacc cgagcagatg ctgtattggc taaagtatac cagccatccg tttcttgact
    32341 tgtcaattct ccttctactg agcctaagtc ttctggcaca tctttttgaa ctgcttccag
    32401 atagtcagta aaattagaat gaataaactc gtaatctgga aacagttcat ttgcgagatg
    32461 gattgctttt gatatatctt tttgtaccgg ttgatgatca acaccattca tcatcaataa
    32521 gtggttcgta gaggcatatt gttctgcatc cgctaatttt tgcttccaaa aggcaagagc
    32581 tgcttctttt tctactggaa tctcattccc gttgctatac caattggcaa atagcagacc
    32641 aaagattgct gtttgatcag gtcctttcca ccacatctct gagtattggg aagaatagtt
    32701 ttctgcttcc aaaacttgat tatcaaagcc aattggtttt acaccacggc caaacgctgc
    32761 tgctgaaata ccagcttgtt tcattaattg aggcgtctgt cccatatttc caaatgtatc
    32821 gggaaaatag cctaacatga caggggttcc ccatttacgg ctttcttcca tgccaatcag
    32881 catatttctc acgttcgatt ccgagctgat aagaaaatca tcttgcaaga tataaaatgg
    32941 tccaattctc aattttcctt cattgattgc ttgttggatt gcctgtcttt tttctggcct
    33001 tacttgaaga tagtcatcta aaataatcgt ttgcccatcc aaatgaaaac tgttgaagga
    33061 cggatcaact tcaaatagct ctagtagatc gtctatcaat tcaatcagtc gcatgtgatg
    33121 ctgttcgtaa gccatgtacc attcacgatc ccagtggcta tgagaaatga tatatacttt
    33181 ctttttcatt tacgatacct cctacttttc tactctaata tcaaagtaat ccatgactaa
    33241 ttcgcaaaac atcatatttg cccaagaaaa ccattctctc gtataatttt caggattgtt
    33301 cacatcgaat ccttcgtgca taaggtgtgt tcctgcgtca gttgctacaa gtaaattcaa
    33361 tatccgctct ttttcagatt tgtctgacgt tgtcattcct tccatagcta atgcaatcgg
    33421 ccaaacgtat ttttctggcg tatgggagga tccaattcct tttgcgtact ttccttcata
    33481 gaaatatgga ttttctttac tcaacaatgt tcttcttgtt tgcagataat cttcctcttg
    33541 ttcagaacaa tatcccaagt aaggtgcggc gatcagattg ggcacattac tgtcatccat
    33601 gactgtggcg tttcccattc catctacttc atatgcataa atcgtttgcc ctttttgatt
    33661 aaccgttcgt ccgtgattct gaatcccctc ttggatctct ttcttcaatt tctgtgtttg
    33721 ctgtacaatt tctttatcat cgagtatcgt ttgaaaaatt tcttccacat aacctaacac
    33781 gaccaccgca aacatattgg atggtaccag atatccataa cggcaagtat catcgctagg
    33841 acggaaacca gaccatgtca ttcctgtaaa agctgttttt gcacctcgcc cgtcattgat
    33901 cagcgtatct tcttttcttg tcgtgtctcg tacaaatgta taaggagagt gttcatgatc
    33961 ttgctctgtt ttgaacacgt ccaagatttt tttgatacct tcaataaaag attgattgaa
    34021 ttgatcagtt tttcctgtat ttttgtaaag aagataggcc aactgtattg ggtagcataa
    34081 agaatcaatt tcatattttc tttcccagat ccaatcgttc atttttgtat gatctgtttg
    34141 gtggccagca ccgttagctt cttcgttgaa ggcattcgca tatggatcga tattgatata
    34201 aaaaaattgc tttttgacta acccgctgat catgtcagct aattcctcat cttcttttgc
    34261 aatcactaaa taaggacgaa cttgtgcagt agagtctctt aaccacatcg ctggaatgtc
    34321 tcccgtcaat aaaaaggtgg ttccgtcatt ttgctttttg actgttgtca acagagtatt
    34381 ggcaaatgct gctgtaaaat tctttgccca gtccgcatgg atatccccac atttttgtgt
    34441 gatatcttcc ataaatttct gcaccgattt tggtatatct ttataagcca ctaataaaac
    34501 cttctttcta tttgatatat ctttaaagat tatacttcat acagccaatt atgtctacgc
    34561 tttcaaaaaa tatcttttta tttacttttt catccattat ggtattattt gaatatgata
    34621 tatcattaag aggtgtttat atgaatcaac cattgtacca gacaatattt aatgatttgc
    34681 aaacggctat tttaactggt gaattacctg tagacagcca actaccaact gaaaaagaac
    34741 tttcacgtac ctataaagta agcagaatca cttccaaacg tgcattgact gaattagagc
    34801 aattaggact tatttatcgc gttcgcggga aaggcagttt cgttaaatcc gcttctccgg
    34861 aacagattct tgcttctcct acaaaaacac gacggattct gtttcttctt ccatatgtcg
    34921 ctgatttgtc tgttggtgat tttagcaagg gattgaaccc tgtgatgcaa gataaacaga
    34981 ttgatgtcat gatgacgacg cttgactttc tacaaaataa aacagcaaaa gagctaatca
    35041 atgaatttga cggattgatt tattatgctc ttgatacaga acaacatctt gacttacttt
    35101 ttgagctttc attgaaagaa ttccctgtcg tcatattaga taaaaaaatc tatgagttac
    35161 cttttcctac cgttctttcc gataatttcc aaggcggtgc gcttgctgcc tcttatttga
    35221 tcgaacaggg acattcaaaa atcgcttatt tgtttggtac gcagactcat ccacaatccg
    35281 ttcgacagcg ttaccttggt taccttgaag cattggacaa agctggtttg actttccaca
    35341 cttcactgga tgacaaaagc gcgacattag atgaattgct ttcttatatc actaagtatg
    35401 aagtaactgc ttttgtttgt gaaaacgatg ttgtcgctat ccagaccatg aatctcttga
    35461 gacagcatgg ttatcatatc cctgaagatt tttcaattat cggatttgat gatatccaag
    35521 cagcagctct tgttgacccg ccactgacaa ccatcgcaca agattttgaa cagttaggta
    35581 agcttgcggg agatgctttg gtcacttggt tagagacaaa agatcgacca tccgatagta
    35641 aatttccagt ttcattcatc aaaagacaat caacaaagga gaaataaaat gaatatcggt
    35701 caaatagata ctagacatgc aacagcgaat cagccaaatt tctctaatgg gaactgccag
    35761 ccttatactg gcgttccttt tgggatgaat tattttgcac cgcaaactac ggatcaaaac
    35821 ggcagctggt ggtttcatcc tgatgaccgc gtttttcaag gctaccgtct tacccatcaa
    35881 ccaagtcctt ggatgggtga tttcagtcat atgctgttta cgccgatcaa tggaaaacta
    35941 caggagaaca cccttttcca tgctcaaagt tcttaccgcc cagaagaaag tatattttgc
    36001 ccgactcatc tgtcgatctg tcaattacgt tatggcatct gttctacatt gatacctagc
    36061 atgtatggcg gaatcttatc tattgattac agcaaaaatg acagcggttt acttttatcc
    36121 tttccgggac gccatcagct ctttgttata gatccttaca cagtggaagg aaaaatcaca
    36181 cattttgctg gttcagaaga tcctgatttt tctttttatt ttatattgag atttgaatat
    36241 cctttaacaa ttgatgagtt agctgtttcc aacaaaaata gcgactcgat cccgttgtat
    36301 tttgaacaga caaaaaaaca aactatccga tttgggacat cttttatcag ctcggaacaa
    36361 gcagcttata acctggaact agaacaaaac caaagcaaag agacttacct tgctcacagt
    36421 caagaacaat ggcagtccta ttttgatcgt atacagctca cacaccatga tcaacaacaa
    36481 ttgcggacgt tttatcataa tttatatcgg gtgtttttat ttccacaaac attttatgaa
    36541 attgatccta gtgggcaaaa aatccactat gatacgacta gtcgatctat aaaacctggt
    36601 gttctctata caaataatgg gttttgggat acgtataaaa cggtttatcc tctttattct
    36661 ttgattgctg tagaaaaata cgaagaaatg ctggaaggtt ttttgaacag ctatagagaa
    36721 agtggctatt tgccaaaatg gctgtctcct gatgaacgtg gacttatgcc tgggacattg
    36781 atcgatgcgg tcattgcaga tgctgctgta aaagatatcc gacgagactt gatgcctgaa
    36841 tttctaacgg caatggaaaa aggtgctacg gttcaaagca aacatccaaa ttatggacgc
    36901 caaggaacag aagattactt gacatatggc tatgttccta atcactacca cgaatcagtc
    36961 aatcacacat tagactatgc ttatagcgat ttttgtatta gccaagttgc caaggtacta
    37021 gaagaagagg aaatgacgaa gaaatatcag cagcaatcat tgaactatca aaatatcttt
    37081 gactatgagt caggatttat gcgttcaaaa gataaagatg gcaagttcag agaaccattt
    37141 tcagctaatc gttggggaca agattatgca gaaggaagtg cttggcaaag cagctttgct
    37201 gtttatcacg atttttcagg actgatcgga aaatatggtg gcagtgagag atataaagaa
    37261 aaactcattg agctgtgcaa tcagccccca acgtttgacc caggaggata tggttttgag
    37321 atccacgaaa tgagtgagat ggccgcgata gaatttggac aattagctat ttcaaaccag
    37381 ccaagttttc actatcctta cttgttcagt tatataggac aacctgaaat ggcacagcca
    37441 ctgcttaaac agttgatgac tcagaccttc gacgattctc caatgggtta ccctggagat
    37501 gaggacaatg gaagtatggc cgcttggtat atcttcaata gtctgggatt ttatcctgtc
    37561 acgcctggaa ccggtgaata tgttatcggt atgccattaa ttgacaaggc tgttttgctt
    37621 ttgtcaaatg gaaaggaatt gacgattgaa gcaacgccta atcggccgca gcaacaattt
    37681 atccataaaa tcaaacggat ggacaaagaa tatacgaaat tatattttac ccatcaagat
    37741 ttgctgaaag gcggcacgat ctcttaccaa ttagggatca tccctcaccc taagaaatat
    37801 caagcaaaag atttgccttt ttccttatca aactataatt aacaagaggt tgtgaaaaag
    37861 ctgtcctgca tcaagtaata agaacagcca agcaaaaata gatcctcata tttttcgttt
    37921 ggttggtctt attaccgcag atgcaagctt ttgaacaccg tttattgaga ggttgtgaaa
    37981 tcagcgttct gacctgagta ttagagagac aaatggcaaa atagttcctc atattttgcc
    38041 attttttgag ctaataccga gggtcagctg attgaacacc gtttagtgga gaggtcgtga
    38101 aaaagctgtt tagtttcgag tattaagaaa aattttgtga aaatggcttt ccacattttt
    38161 gcataaattt ggcttaatac cgagaaactg gcttttgaac tccgtttatc gagaggtcat
    38221 gaaaaagctg ccttgcctca agtaataaga acagcccaaa attagatttc tagacaattt
    38281 tttataagtt atttcattac attggctttt tcttttatga ttctccactg ttttctcggt
    38341 actctttagg ggatctgccg acgattttct tgaataattt agagaaatac gtggtgttgt
    38401 tgtagccaat ctcacttgct atctcattga tgttttgatt actgtgcaaa agcagttgtt
    38461 tcgctttttc catacgtaaa tggttcaaat aagctgaaaa actttttttc gtttcttttt
    38521 tgaacagctg tcctagatac atgacattta aatgcaggtt ttctgacact tctttgagtg
    38581 taagtggttc ttgataatgc tggtgcagga ttacgattac tttttccaca ttgtcactgt
    38641 actttttctg tctctgatgc tttttgatga atgacagaag tagctgctga agttcttgca
    38701 ccgtttttgc ctgatggatt ttttcgattc cttgtaaata ttcctcatct tccagatcaa
    38761 tcaattcccg ttgaatctcc ataaacagta aaaaactgga atatcgtata tcttccggca
    38821 tcatggctgc taactgaaac tgttcaaaaa aatcagtgat cattttttga gcgacttcca
    38881 attgtttatt ttgcagcacg cgtctgaaac ttgaaaaatc gatggtttga tcttttgttt
    38941 ctgcttgtac tgcgtaaaaa acatgctcgt ctttatctcc ataaaattga tgcaactgta
    39001 gattgtcttt cgcttgttgg aatgtttcag ggattttgtc caaagaatct gtctcttccc
    39061 cgatactgat cagccattcc tgatcaggaa agttttcttg aacaaaacaa cagaagccat
    39121 caacttcatc tgcctccaac aacaacgtga tcaatacacg gtctccgtaa tttcgttgat
    39181 agtaaaagat ttgttgccgt tcttgcaacc atctattgat aagagtatca tgagttcttg
    39241 ccagttgaat caatactatc ctatgctgct tctcacttat ttgtcctatt atttcttctt
    39301 cacttatttc atccaattct tcattcaacc attgactgaa taacagttct tgatagattt
    39361 cttgttgatt tttttgttca ttttgctgat ctaaccgtgt tttgattttc ttgaggcttt
    39421 caaccaattc gaacttattc acgggtttca tcaaataatt cacggcgcct aattgcatac
    39481 ctcctttcaa ataatcgaat tcttggtatc ctgataaaat cataaattca aaattatgac
    39541 gttctttttg agccgcttca ataaattcca gtccatttat ttctggcatt gtcacatccg
    39601 ttactactaa atcaatctgt cgctgttcaa gtacagctag tccttctttg gcattctctg
    39661 ctgttgctac tatttgaaag cctaaacttt gccaatcaat tatctttttt aacccattca
    39721 aaatcatgta ttcatcatct accaataaca cttgatacac gctcatccct ccttgaatgt
    39781 aatagaaacg gtcagtccac ctgtctcatt attctcaagc gacatataat aactgctgcc
    39841 gaagctggca cgtaaacgtt cattcacgtt ttgcagaccg atagaaccgt gaagttccac
    39901 tttaggatga gacagttttt cttcaatctg ttttagccgt ttttcagtca tcccttttcc
    39961 attatctttg atgatgatcc ttacccgttt gccttcctgc aagactttga cacttagcgc
    40021 attatcgaat cgagtaaaat caataccgtg tttaaaataa ttttcaacta atggctggat
    40081 cacaaattta ggtacttcga tcttttccaa atcaggatcg atcataaaat gataggctac
    40141 tcgattagga taacgcattt gatacaaata gacatatttt tcgcaaaagt ccagttcttc
    40201 ttttaaagtg atcgttttct cttgattcgt attgtttcga agcaaagcgg aaaacgcata
    40261 cacaacatct gctaattctt cacttccttc gctgattgca tacattcgga tatattctaa
    40321 tgtattatat aaaaagtgtg gattgatctg tgcttgaagc gcccgcatat gtgcgtcttg
    40381 ctgtttgatt tctaatttgt agatgtcttc tacaaactga ttgatgctat ccaacatttc
    40441 gttgataccg attgaaagtt ccttcagttc atattccgtg tttgttatgt cgatccgcgt
    40501 ctctaaattc cctgctgctg tttgatccat ggcctgcatg acgatagata cttgctgtga
    40561 atatcgtttg aatgttttat aaagaaagat aagcagtata ttgtctaaaa taatgatacc
    40621 aatgatcagc ggggcaagat tttttcccgt ttcgattttt acactttttt tatctagtac
    40681 agctaatata cgataatcat cagacagttc ttggtgttga acaaaattgt ttttttccag
    40741 atcgtcaatc ggcaattgtg aatttttctt cagactctct gtgatgatca tttcttgtct
    40801 ttcaaacgtt tctttagcta ttttattatc atggaatgtg tatagtcgat ttgtcgttcc
    40861 agaaatcatg tataaagaga gtccattgaa tgacgttaga ttttctaaaa tcatatctag
    40921 ttctttcttt tgaaaaccaa taaaaatact tcctgactca gctcctcctt gtgtgatagg
    40981 caacttgata taaaaggcgt ctagtaattt tggtgtcccc ttttttattt ccccaccttt
    41041 gttttctcta gaagattcat aatactccgg tagttgattc aacacgatat atatcgcact
    41101 tagttcttca taatttgcgt agagatcttt gatttgattt gggaaagaaa ctaattcatc
    41161 ggtactgttt tgctgttcgt atacatacat cagatactga tctatgggtt ttgttaagta
    41221 ggtcgtcaca ttttcgatct tttcggaatt ccctacaagc tggtttttga tgatcctact
    41281 caaggttgtt ttatcattca gcattctgct tgtgctttga acggcatcac ttgtcatgtt
    41341 ttctgcctgt ttttgatttt gttcccaagt atggatacta aaaataacgg tagcagtcat
    41401 cgttacaccg atcatgataa ccgcgtattt ccgcaacaga cgatttagta aggttccttt
    41461 tgaaaataga atccgaaact tattcataac tttccaactg tttatctaat tcttcacgcc
    41521 aatgtgttgt catcgtacca ttccaaaccg tcaaaagacc aatgacacca aacaggatca
    41581 atcctttgaa ttgccaagtc acgcctaaaa ttataccgct accaataatt atttttagaa
    41641 aagacgaaaa gctggaaaaa accgaaataa aacttagctt tagcagatta ggaacagaga
    41701 tcgtatattc actatctaaa atcatactgt attgataagt agcaaatagg cagagcaagg
    41761 caaaaagtaa aataaaatca atagctaaaa aaatgagccc tttgatttga acagataaat
    41821 ataaattgta actcaataaa gcagtaccag ataaaaataa actaaatagc agattgcctc
    41881 ttaaaaaatt tcttttatat atattccagc ctctttttat tgtgatttct ttatactcga
    41941 atccgtacaa ataaaatagt tcattgactg ttttccatgc cgcacctaat ccaaagatga
    42001 tcccgccggc aaatgtatat atccagaaat acaaggttag ttttataatg acccagatcc
    42061 ggataaataa ctcttccaaa accttcccta acatatcttc tcctccaaac attaagttta
    42121 tactttctca ttatacaaaa aaaggttggg caatcagcac cttgacctga ttattagaga
    42181 aacaaacgga aaaatagttc ctcatatttt gtcgttttgt gagcgaatac cgagggttag
    42241 ctgattgaac accgtttacc aagagtttgt gaaatagccg cttagtttcg agtagtaaga
    42301 aaaattttgt gaatatggct ttccacattt ttacatatat ttagcttaat accgagaaac
    42361 tggcttttga acaccgttta ttcggaacaa gaggttgtga cacgtctttt gtcacaaccc
    42421 ctttgtcttt attcattatt attcttgtcg gaactcatca tattgttttt gcatttcttt
    42481 caatacctta tcatagccag ccttgtccaa agcgtctttc aatttcggta atgtttcatc
    42541 tggatcaaca gtccctgtat tcaatccatc taaatattga ttcatgacat tagaaatatt
    42601 acttaattct gttttgacac tgtcagtgtt gaagctgaat cctaaaatcg gtgaagtttc
    42661 tgcatcagca atcgattgat cacgtttggc aatcatgtca tccgtaatag actcttgtgt
    42721 atatagaatc ttgttgtttc ctgtattcca agcagacata tgtgtatttg gctgataacc
    42781 atctagcaat ttgattttat catctgaacc atcgactttt tcccatgctt ctccctcgat
    42841 cccccaaaca agcccattca ataattctgg atcactgtta agcagcccta gaagttctac
    42901 tgatttttct ttattttttg aagtatttga tacgacaaaa tttgccattt gtgcttgagc
    42961 tgtagatttt agtggaacag taattgcttt tgagacaagt tcttgttttg ctgcatttgt
    43021 caaaattgta tcgccataat catacggtcc ttgtgtttct ccacgcatta gccaagtatt
    43081 tccttctagt ggataatcct tattgctcgt tgcagcgtca cttggaatga gtccttgttt
    43141 gtaccagcta tgcattgtac gtaacagtcc gatatacgtt tcattatcgt attggttgat
    43201 gattttcgaa tcatctccat ccagatcaat agcaaatggt aacgtattcc ctaaaggata
    43261 atcaaagttc ccttggactt tgaagccttg tccaatggca aaagctgccg tgtttggttc
    43321 tttttcatgg aattccttca agactttttc tgcatcagcg taagattgga ttccatcaat
    43381 tgaaagatcg tatttatcta gtaaagcttt gttaaaagta agtacttgtt gagcaaagac
    43441 atttccattg actgggaaag catataattt tccattgacc agatttcctt taatatatgc
    43501 ttcatctaaa tcattataag ctttttcagc gtacttaggc gctaattcag tcaaatcagc
    43561 aaaggctcct ttttgggcat tggaaacata gttgttcgca aaggcgatat cataattttc
    43621 cccggaagaa atgatgacgt tcattttctt ttcgtaatcg ccccagccaa tgtaattgat
    43681 attgactttt acaccgatct ctttttcgat tcgtttgttt gctacttcca tcaattgatc
    43741 gaaattatct ggtttatctc cgatttgata catctgcaaa gtgtccgaat tgctagcttc
    43801 tgcctggtct ttagaaccag aacctccgca tgctgctaat gttcccaaca acaacgctga
    43861 aacacctgta aaggctagtt tcttccataa cttcattttt cttcctccta attttatgat
    43921 ttatattttt gtttctttat tcttttactc cgccgattgt tagacctttg acaaaatgct
    43981 tctggaaaaa tggatagctg atcgcaatag gcaacgtcga gatgactacg atcgccattc
    44041 tggcagattc tcctggaact gaggctaatc cgcctgtcaa ttggcttcct gctcctgaat
    44101 tttgtgtcag atattgaata ttactttgga ttttcatcaa aagatactgt agtggaacta
    44161 gcttatcatc ttggatgtat agtaaagcat tgaaccagtc attccagtaa cccaatgcgg
    44221 caaataaact gattgtcgca atacctggaa cagctaacgg caaaacgatc tgaacaaata
    44281 ttcgcagttc gctagctcca tcgatccgtg ccgattcaat aatcgaatca gagaccgaac
    44341 gtttaaagaa tgtgcgcatc acaataatat tgaagggact gacagccatt ggcaagatca
    44401 atgcccaaat cgtatctttt aactgaagaa gatttgtcat aacaagataa ttggccacca
    44461 tccctggtga gaacaacatc gtaatcaaac aaaaaacggt aaaaaaacga cggaatggaa
    44521 agtttgaccg tgaaatcgca taagcatata aagaagtagc cgtgctattg atcagtgtac
    44581 ctaaaacagt aacaagtaca gtgacgaaaa gcgcttggaa aattttatcc tgcatctggt
    44641 cgaacaagta cgtataacca aatatactga acttttctgg ccaaaaactg tacccgtgag
    44701 tcgacaatat ggactcatcg gtaaaagaga tggcgataac aaatataaat ggcaaaatac
    44761 aggaaatagc aaagagtgca atcattatat tagagaaaaa attagccgtc ttattgaaag
    44821 agcggacttg gactctctcc actttctttt ttttcatttt tttcctcctt agaataatgc
    44881 agaatcgcta tcaaaacgtc gggcgatcgt atttgtgatc atcaacaaga caaagccgac
    44941 aactgattgg taaagtcctg cagcagccgt cataccaaaa tctcctgtgg atgtcaggcc
    45001 attgtagata tacgtatcca aaacttgagt cacatcatat aatgcaccgg aattcctagg
    45061 aatgttataa aacaggccaa aatcagctcg gaaaatgttt cctacggcta aaatcgttaa
    45121 aatcgtcatt agtggaataa gttgtggtat cgtcacatgt ttgatctgct gccatttgct
    45181 agctccatca accatagcag cttcataata agtcggatcg attcccataa cagatgcaaa
    45241 gtaaataatg ctgttataac caatcccttt ccatgtacca atgaacacca agataaacgg
    45301 ccaatatttc ggttcattat accaattgac agcttctcct ccatgtccag tgatccactg
    45361 attgaatatt cctttgtcag gacttaaaaa agcgtaaaca aagtaactga taatgaccca
    45421 agatagaaaa taaggtagta aggacatcgt ttgataaact ttaacgagtc gtttatttct
    45481 caactcgctc ataatgattg caaatacgac tgagatcagc agattcaaaa ggataaatgc
    45541 tacattatat aaaattgtat ttttagtgat gagaaatgct tgatccgaag aaaataaaaa
    45601 tttgaaattt tcccaaccca cccaaggact ttccctcaag ctagccaaga acccatctgc
    45661 tgaaatatga aaatttttga atgctacgac attcgccatt acaggtatgt aaaagaaaaa
    45721 aatcatccaa agcatacccg gtacagccat caggacaagt gctttataac gccatagatt
    45781 cataaaaaaa tgattgaacc cctttcgttt tttcatctaa aaaccccttt cgattcattc
    45841 gcaacgtaat tatagcgctt tcaataatga gaataaataa acaaagtata gggaaaatga
    45901 aacaaagtat aggagaggtt gtgaaatcag cgttttggcc tgagtattag agaaaaaaac
    45961 gggaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt cagctgattg
    46021 aacaccgttt atcagaggtt gtgaattcag cgttttggcc tgagtattag ggagatcgtg
    46081 tccttactat ctaactctga gtcacaagga acaatgggga ctgtaacaaa agtcttgtca
    46141 cagtccctta ttccgaacaa acggtgttcc agaagtagct tctacggaaa taagccgaaa
    46201 tttcacaaaa aagccatccg aaagtcagac ggacaagtct gcttttcaga tggcgctaca
    46261 actactctgc ttattctttt agctatccat tcaattattt ttctctcact tgttctagct
    46321 cttctttggt catgggtcga tattgccctt tattcaaatc tttaggcagc caaaattttc
    46381 ccatacggat tctttttaaa tataagactt cttttcctac tgctttgacc attcgcttaa
    46441 cttggtgaaa ctttccttca tgcaaaatca gacggataat tgaagtttct gtctcttgat
    46501 ctacttgatc aatttggagt tttgccggca atgtctgctc atcgccatca ataatcagtc
    46561 cttctgcaaa taaacggata tcttcttctg tcattatacc gctaacctca gctagatatt
    46621 ctttctccac atgtttttta ggtgatagta actgatgggc aaacaccccg tcattcgtta
    46681 aaatcaagag gccctctgtg tctttatcta atcggccgac tggaaaaaga tcttcccgat
    46741 aatcctggtc ttccaataaa tcgattacgg tttgatcatg attatcctga gtagcagaaa
    46801 tgactcctgc aggtttatgc aaaatgtagt aaaaatcttt ttgatacgta atgatttctc
    46861 ctaaataagt aaccgcatct tcgaattcat ttacttgcgc tttatcgctt ttcaccactt
    46921 gtccattgac ttcgatcgtt ccttttttga ttaatccttt gacttctttg cggctgccaa
    46981 gtcccatatc tgctaaaaac ttatctaaac gcatgcgttt cccccatttc aaaagagcat
    47041 caatctagct cttctgattc acttatttta tttttaattt atgtcgtaaa cgcgctattc
    47101 ctggtcctag tagtctttct gccaagcgga ttttcaaagc taaataacca tacactaaag
    47161 cccctatacc tgctactaca agaatcaaca atagagactg gaatttgcta tcttcgttta
    47221 aaaaagcacc aaaaatcatc tttgtgatcc acgaagccaa aagcataatc aaggtaagaa
    47281 taaagatcag caatgtcctg cgccagacaa aacttggttt aaagcgggct acttcatgga
    47341 ttctctttaa gatcaaggta caagacacag caaatccgat cattgtcgcc aataaagggc
    47401 cgtatacttc aaataaacga atggctgggt attgaagaag gagtttcact agaaacccaa
    47461 taaccaaata attaattgcc gccttgtttt caaacattcc ttgcagcatg ttggaaacta
    47521 gcatatatag tcctaggaag agtcctacaa aacttgcttg gatcagtaca ttacttccta
    47581 gagaatccgg tgtataaaat aatgtattta gcggataggc aagtaacata acaccaaatg
    47641 tcgccggaaa cataaaaaat gaaaacaact gtaaatttcc gcttgtcaat tttgccagac
    47701 ctactcgatc tttcaacgta acagcttctg taatcaacgg taacccagta gacgcgatcg
    47761 atgttgccaa tgcaataact accatcgtca acttatctgg attggcacta aaaatcgaaa
    47821 aaagatccag taactgtgca ttggaatact cggtggatgc agacatgatc ttcataaaag
    47881 tgaactgatc gactaatttg aagatcgtta cccctgaacc cacaataata aacggaatcg
    47941 cttctttaac ggtatctaac aacaattcct tcgttgcaat atttattttg ttttcgctgt
    48001 agtgaataaa cgccgatgta tacgcttgat gtttcttcaa aaaatacaaa aggacaagaa
    48061 tacttgctag cataccgata aatgccgcga aagttgattg cgtgaccgcc gtcacatagt
    48121 caccatccat gactttcatg atgatgaatg tagccaatag catataaaaa atacgtgcca
    48181 cctgttctac aatctgcgac agcgcataag gcatcatttc ttgattgcct tgcaaatacc
    48241 ctcgtatcac actcatacaa ggaaaaacca atacagcgat actcaaagaa cgcatcgttg
    48301 gaatcagttc ttctccgcca ccagaagcat gagctagcca aggagaggcg atgtacatga
    48361 acaaagcaaa caacaggcct aacccgccca tcatctgtaa tgcacggata aataatcgtc
    48421 gtgaagtgcc atattcattc aatgaattat agcgtgcagt ttgttttgca atcgcagcag
    48481 gtattcctgc tgtagagatc agtagaaaca atgcatatat attgtatccc atattgaata
    48541 atccattggc agccttagca ttttcgccca tccaagcata ccagggaatg atatagacag
    48601 cgcctagcaa tcttgaaatg atattactgg cggtcatcca agcagagcct cgtgccattt
    48661 tttcttgcgg tgttaattga tctaatgctg gttttctttg attatccatc ggtcagattc
    48721 caactttcta caaaacatta ctatcatttt aattggtaaa acagaaactg gcaatcgatt
    48781 ttatataact tttataagaa caattgtttt tttgaattcg gtttcgtttt tttggtaaag
    48841 taaagaaata tacagccttt tatggctaac atttatagga gatatcaatg acacaagaaa
    48901 taaaaaaact acccgttata tttttaggtc ttttctttat cacagttgga ttgaattggt
    48961 tcttgctccc tcacgatata gcttccgccg gagtgggcgc catcggacat ttagttgaaa
    49021 cggccttttc tatccaacgc tcagttactg tttggagcat caatcttatg atgctgcttc
    49081 tagccgctgt cctattagga aaatcagtat tttttaagac tgtagcggga agtctgcttt
    49141 ttcctgttgt tttagagatt gttccaaaag tggaaatgat ctcctcacat ttcttttcac
    49201 tgatttcagg aagtcttttg ttcagtcttg gggtttacac attgtacaca gtcggggcct
    49261 caaatggcgg tataacgata ccgccgatta ttttccacaa attttttcgg cttccaatgc
    49321 cgcaaggact tttacttacc aatagtctta tcgtcttttt gaattattat gtttttggat
    49381 tgttggagac actattcgtt ctcctatcta ttacagtcag ttcattgttt atgaaaatac
    49441 tcatccgctt gtcccctgtg tcaagaaaat ttgaataaag ctggattttg tcatagcgga
    49501 aacaaacgat atattaaaaa gagtgtgcta taataaacca agaaattgaa taaagcgagg
    49561 gatcaatcaa tgagcttctc tttagaagac atccgtcatt tactattaaa agaaaatcta
    49621 ttaaaagaat ttgtttcaac aagaggctgg catcttgatg taccagaaaa agctgaattt
    49681 cttcagttaa gttatgattc aagaaaagct gatgcttcta ctttgttttt ctgtaaagga
    49741 atgaatttca aagaagaata tttggattca gcaatcgaac agggtattca atattatgta
    49801 tcagaacaac catacgaaaa ttcagcagta ggaatcatcg taacggatat ccgtaaagca
    49861 atggcgcttc ttgctatggc tttttacgac tatccgcaaa ataaattgaa agtgatcgga
    49921 ttcactggaa caaaaggtaa aacaactgct gcgtacttta caaaagcaat cttggatcac
    49981 acaacaaata aaaaaacagc attgctttct actatgaata caacgttaga tggcaaaaca
    50041 tatttcaaat cccatttgac aacgcctgag tcattagatt tatatcgtat gatgtcagaa
    50101 gcagttgaaa atggtatgac tcatctagtg atggaagttt cttcacaagc ttacaaaaca
    50161 caacgcgtat acggcttgac tttagatgtc ggaatcttct tgaatatctc gcctgaccat
    50221 atcagtccga tcgaacatcc gacatttgat gactatttct attgcaagcg acaattgatc
    50281 ttgaattcaa aaacagttgt tttaaatcat gaaagtgact attttgattt acttagggaa
    50341 acagccgatc tattccagat tccaacgatc acttatggtc gttcggaaga aagcaattat
    50401 caagtgatcc gttcagataa aggtactcac ggttttactt tatcttctca tgaagatcgc
    50461 ttagctatct gcgatactgc ttatgatatt ttgctggctg gaggattcaa ccaagaaaat
    50521 gcagccagtg cgatcattgc cgcagcacta acaggtgcct ccagtcaaga tgcacaagac
    50581 ggattaaaag aagctcgtgt accaggccga atggatcaat tgatccaatc caatggagcg
    50641 catgtctatg tggactatgc acataattat ctaagcttga aaacattgct gaaatttgcc
    50701 aaaaatgaac atccagatgg ccgtgtaatt gttgtattag gcagcccagg aaacaaagca
    50761 atctcccgtc gacatgattt tggaaaagtg ctatcagaaa cagctgacat cgcctttttg
    50821 acggcagatg acccagcatt tgaagatccg aaaaaaatcg cggaagaaat caatgaagca
    50881 attactaatc cagatttgat cgttcattat gaaatggatc gtcctgaagc gattcgacgc
    50941 gctttagcag aaagcgctcc gcaagattca gtcgttattg cgggaaaagg cgtggatccc
    51001 tatcaaaaaa tcaatggtgt agatgaacct tatgaagggg attatgcaat cgtgaagcgg
    51061 ttgattgaag aataatggta tttatatact agtggtttcc catttctaag aaaaaaaggg
    51121 actgtgattt tttgtcacag ttcctttttt cttagaaatc attttaactt ttcactagct
    51181 aattctgctg ccttttctct ttcttcattt aataatttat tatcatagaa tttgataaat
    51241 gggaaccaga taatgaatgc gatgattgca caaatgactg ctaacacagc agctttccaa
    51301 tcaccaccac taccaacaaa tgctccgatc ccgactggtg aaggccacgg catctgtgca
    51361 agcatcggtt tgacgatttc cagccgaatg gcaaaataag cgagtgtagc agaagccatc
    51421 ggagctaaga aaaacggaac cgctaaatag ggattgtaga cgattggcat cccgaaaatg
    51481 attggttcat tgatattgaa taatcctggt acaagtgagg cttttcctaa cactttcagc
    51541 tgatcagatt tcgcgaggaa tgcaataaag atgatcaatc ctaaagtcgc acctgatcca
    51601 ccaacggtta cataagaatt gttgaattct cctgccaacg gataatttgc gccttgtgcg
    51661 ttagctgcca tattagctaa tacgatcggg gtcaagaaag aagtgatgat attcgctcca
    51721 tggatcccta cgatccacaa tgcatggatc aagaaataaa tcaccatgac accaagccat
    51781 gtattcgtca actgcgtaac aaacccaaat gggatagcaa tcattttgaa gatatccgtt
    51841 cctagtgcaa ctaataatcc attgatgatc atcaccacaa acgcaatgac aaatgttggg
    51901 atcagagcag tgaaagaacg agaaactcct ggcggaacaa catctggcat ttttatgacc
    51961 caatttctct tgacacacat acaatacaat tcgaccgcaa taatcgacat aataatagct
    52021 gtaaagattc ctgaagttcc taaacgttcg acaaaagagc ccatcctaat accatttact
    52081 acagtttctg tctcattgat agaagcaatc aagctgattt taccatcagt catgatcaat
    52141 tcagggatac acataaagaa tgcaaaaaca gatagtaatg cccccgtgag cggattaaca
    52201 tttaattttt gttcatctcg ttcaattgac gttaattcat aagcaaacac aatggcaaag
    52261 taaatagata aaatccccat cgtcattgta ttgacgatca tgtacaagtc actaactttg
    52321 aaaaaagttg cattaaaaaa tccttctaaa aatgggaacg gtaatggcaa aatatttaaa
    52381 accaaaaaca tcgagcctac aatcgtgaaa ggaatagaag ccatccccgc tgccatgaca
    52441 gcccgaacga ttttaagttg cgcaattttc cccataggtc ccatcaggta tttctgcaaa
    52501 aaatcaaaca ttagttattc tcctttccta aatataacgc tttttcatat tgtttaatac
    52561 ggatatactg ttggtcttgg ttgagtgaaa ttttctttaa acgatactgt ataaatgcac
    52621 tggcaaaaat accgcttaca acaagaatga aaacaaataa ctgtcctcca ttgttatttg
    52681 ccataaaagg atacaagaat gtaaatcctg aggtaaacaa cactggaatc actaataaat
    52741 taaagacact ctggaacaaa aaataccact ttgtccatgg aacgttcgtt tggtgttttc
    52801 gataaagctt tacttgttct cctactgcag gcaaaatagc taaaatcaga atcatcggta
    52861 aactacttcc taaactttta gctgatagaa gcagaatcat ccattgcatg ttcatgaaaa
    52921 agaaaaaggc agtcaggtaa cgtacgatta gataacgatt gaaatacatg tttttcaaac
    52981 taagttgctt tttttctaat tcgattttcc tttttactgt atcctgcaca atgatccttc
    53041 ctttctattt atttttttga tacaaataat tcatttcctg tgcaacttcc aataatgtca
    53101 tcgtcgtcat cagatgatct tgtgcatgga ccatgataat ttccatttct atttttgtcc
    53161 cgctggcata ttctttcaga agttgagttt gtgactgatg cgcatgaaga atctcttcat
    53221 ttgcttgtcg caacttctct tctacttctt caaacatctc tttacgcatc gagcgaaatg
    53281 cttcatgtat cagtgtccgt gcatttccgc tatggaaaat gatatcaaaa gaagtcactt
    53341 gtagtgtttc actgtttatt ttttcagcca tctgttttcc tccttattcg atcagtttga
    53401 taaatttact gctgaaattc tcaaaaatag gttcagctaa gatttcctgc tgtactttta
    53461 gctggtcaac taacctaacg attgctttag tcacgaccgt aattccttca ttttcgacat
    53521 aagaaggcga aactaaaaaa acaaaatgaa tttcttgata ttgatcccac tgcatcccag
    53581 aaggaatcaa tgcaacggct acctttgttt cgattccaac tggaacagcg ggatgtggga
    53641 ctgccactgt atcactgaat atgatttgtc ccatattttc acgttgctgg atctgctttc
    53701 gcatttctct tatatatcct tcttcttcat ttatgctcag cttttgcagc aaatcatgaa
    53761 gaatttcttc ctttttcggt tcgtacgtat aagtcttgaa aaatttttca gacaactgtt
    53821 cggtgtaaat ctgctttttt tgctgtagag aaaatgctgg tatcggtcta tctgaggaat
    53881 gatagggtat agattctcca actacctttc gtattttacg aacatcatct tcattcaaaa
    53941 aaatactgac atgtaaaact ggaattttga aaaacattgt cgaaagatca atagaagaaa
    54001 taatcaggtc gattcctttt aaagttgttt cattgatctc ataatagcct tttacactta
    54061 ccactgtaat atttttaccg aattcactga ctacgcgatt ctttaatagt tgggcactgc
    54121 cgtaacccgt tgcacagata atcaatgcat gtagtttatg cgcagctctt tctttttcca
    54181 atgccgccat gagatgcaaa gccaaatagg cccattcatc ttcattgatg gtatagtttt
    54241 tcaaagccgg catgttgctg aaatgccttt ttactgcgtc aaagactttg ggattttctt
    54301 tctttatctc ctcagtcaat gggttctcaa tgcgaatacc tcggctcaat cgaatcatca
    54361 tcggtgacaa atgatcgagt agtccattga aaagctggag atcctctact aatgaaaaat
    54421 gaaattcctg agacaatctt ttcagaactt tcgctaattc ctttgatagt tcctgatcat
    54481 tttgattttc tttgtgattc gacttagcca tgagatgtaa tgtcaaataa gcaatttctt
    54541 cttcgggaaa cgatacacct gcgattacct caatacgttg aacgatccgc tgcgccactt
    54601 gatactctac tcgcttagaa acttcttgtt cgatgcctaa ttccttgatt tcaaaccctt
    54661 ctcggagccg tttgatcccc aaagccaagt gtaaagtcag attctgtatg ataaaatccg
    54721 aaacttttaa cttagcttct cttgtttcat cgagaatgat aatgactagc tcttcaaaac
    54781 tgatgtctgg gaaaaaacgg ctttgcccta aatattcttt caatgaattt ccataatggt
    54841 ttccaaaaaa agtatccatg ataaaatgcc gtcgatttct ttcttcccct tcgatccatg
    54901 tcccttgacc atgcttagaa acgattttta gtgaatatgg aatcaatcgc tccttgattt
    54961 cttgcatgtc ctttgtcaaa ctggaacgac tgatataaag ctcttctgcc aaatcatcca
    55021 taaaaagaat ggcatcttcc aaaagcaatt ggttcaatat atacttttgt cgatcttcgg
    55081 actcataaaa tccttgcggt tctctagcat atccaggtac tatttcttgc cgactcaaaa
    55141 acaagtcaaa tgtcagtctt tgtaaaatat gcagttggta gccataacct ggtttagcaa
    55201 tgatcttacc tccgtttttt tctactaact ctttgatccg ctgcaagtaa ttacggattg
    55261 tccgatcaga taataacaat tcagaagcta aacgttgact ggtgacatac tccttcttgt
    55321 gatcaatcaa atatctcaac agcaattttt ccttctgttt cattatcatc cactcctatt
    55381 ccatcatatg ttctcttcga tcacctctgc taacttctgg atgcctgtag ggattgggac
    55441 atacgcttgg aaagggatac taacaacagg ctttccaaca gattctccta attttttgaa
    55501 tttatccaaa aacatcgtcg tttgcgggct gatcagaaat aaatcaaaat cactattctt
    55561 aatcatatta tcgccttctg tagctgaaac tgcatctacg agtacctctt ctcttttttg
    55621 cttaaagaaa tccgttgtct ttgaggccat catcgaggat gacattcctg ccgcacaaat
    55681 aatcaatgct tttttcataa atcaatcact ccttttattt ttataaacca agcatatctt
    55741 gtaagcgttt tctattcaaa atatatattt ccgtagcatt gcggaaaaaa tgtgtatcat
    55801 atcttgaata ataatttctg gcaccgtgat atactagtga tagaattttt tcaggagggg
    55861 atttagtgag tatcacagtg aatattttgt atacaagtac aaatggacaa gccagaaaat
    55921 ttgcagaaga aatggtcgaa agaaacattg tcaaagcgat tcgtgcagaa gaaggaaacg
    55981 agaaatatga ctattacttt ccactagaag atccagaatc tcttttactg atcgaccgtt
    56041 ggaaagatga agaagcaatc gaaaagcatc acaaatccga aatgatggct caaataaacg
    56101 aactccgtaa aaagtataaa ttaaaaatga aagtcgaacg tttcactgat ttaccgtaaa
    56161 aagatacaca tggaatgata gcaatttatc atccatgtgt atcttcactt tttccttatt
    56221 ttttattcga tctcatctaa tgattcaaac cgtgtttttc tcttattttt cggataagta
    56281 tttcagtcac cccaatatac atgattccta aacatacccc aaggatattc tcaaaaatgc
    56341 ggatcgttac tgctcctgga accccgaata aactggcagt gattgccaaa gcaccaaaag
    56401 aattaaaaac tgttttatat ctataggtag aacaaacacc taaagctaga ccacctaata
    56461 taccgaccca gttaaaagga ataaattggc tgataccaat aaataaaaca catccaatca
    56521 atgagccaat gattcggtct actgctcgtt ctttgaaacc aatcgacatc aatccatagc
    56581 tagatacaat agaagaaaat gcaaaccctg cccacatcaa tcgctgaaaa gggacatact
    56641 ctcctgcaac gatcaaaaga ctaatgccaa atgcatagat gagcatccaa attttttcct
    56701 gcgaatacat gcctttcaaa aaaatctctt taaacaagct tttgtctttg ttcttttctc
    56761 gatgttttct gtaaaggaga actgaaaacc aacaaaaaaa caaaaataat aagctacttg
    56821 tttgtgtaaa gaaattcttg ttcaacgaat ctttaggtaa cgaataaaca ataaagagat
    56881 atgaaaagcc gtacaaagaa gcattcccca ttttgggatc actagcggtt gccattaata
    56941 tgctgcttag taaaataaaa tgaatcaaca tgcccataac tgaccatttg atcagctgga
    57001 catacggtgc tactaatagt gagaacatga cgattgctaa acctatgatc gaatgggaaa
    57061 tcttataacc aaagtcaaca aaacgaatac tcatcaacat acagaataaa accacagcgt
    57121 atggtttatg cttcgattca aataatgttg taattataat gataaaacaa atggcaaaca
    57181 atacgatgaa taatgatcgt aaaaacaatg aacaaatata catgcacttt tcttttttag
    57241 aagctgcttc tcgtattttt tgttttaaaa taaacggatc tagttgtaga gactgataaa
    57301 aatccacctg ttgtcgtcct ttctttttac ttttattttt tacagtcatc tatgacaggt
    57361 tgtaaatact atggaacatc atatggcgtt gtcattttct tgtcaactat ttttcctatt
    57421 catgttttta taaaaaaaca tatcgttttc ttgtatgatt aaatcaccac aaaataaaca
    57481 actgagagaa cgatatgctt tatgaatggt tctatcaaaa aaattctgag atcaatagac
    57541 aaaaatttga tgattacaga ggtctcttac gaaaccttac agaagaaaaa aacattgatc
    57601 gttgctgcag ttctcttccc tgctccatgt gtctgtagaa attgtggttc tgctgtggta
    57661 gatggaaata ggaaattaat ggtggtgaaa aacaagaaga aggaaaccat tgtccacttt
    57721 gaataatata atcatatgcc aatggttata cgcctaaaaa agcagcgcta tacctgtaaa
    57781 aactgtcgaa gccattggaa cgctcaaagt tattttatcc gtccaaggca ctcgatttca
    57841 aatcatgtca gacataaaat cacttcttta ctgactgaaa aagtgtcgtt attttttatt
    57901 tcgaaaagtt gttaggtatc tttgacaacc gttattcgca cattgaaaga gttgagaagc
    57961 tatttaccaa agtcttccaa aagaattctg tcttgagtgt tgagggttgt gaatttcgtt
    58021 ctcacgtttc cgttgaggat aaactgagtt ttatttccgc ggatggcgag acagaaaaat
    58081 taatcgagaa aatttaccta cacaaaaaat tcctcgatta acaaactatt tccttagctg
    58141 cactaatcct aaagaaatag aattcttagt tacagacatg aacgccacct actttcagct
    58201 caccaaacat gttctaccaa atgcgaaatt ggtgattgat cgattacttg gtttttccac
    58261 gcctttcaag gaggcgtaac ctttattcac gagttggttg aagctttccg agacaaaaga
    58321 cccgacttgt ttttctcctt attgacaaag agccattaaa actagagaaa aaattacaac
    58381 tgatcgctga ttatttgtag aaagaaaatc aaagtattac ccaataaact tgagtcatta
    58441 ggcaaaaaac actgcgaaac tcaagaatga ttttcgcagt gtttttgtat attttttatt
    58501 aactagtatt actacaaagg tttatttttc acttctcaac gcagcacaaa attgtcttta
    58561 cttatttact ggttgggttc aaccttctct actccgatac taatatttgt ttgtataccc
    58621 cttctaaaat cggtagtttc cattcaattg atgggtacta gttgatttta aaaactatgc
    58681 ttattcaatt ttttatttta gctcatatat ttcgtttctt tctaaatttt atactgatga
    58741 aaacaagtag cacacccaat attgacaata taaactggct aatgatggtt tctccagttt
    58801 ttggaagatg cttatttcca ctgcttgttg gattgtttcc tcttatatct gagctatcag
    58861 caacttttct attctctttt gttaaaaaga tcgccacttc ttgttctttt tcgatcttga
    58921 aagttactgg tgtcgcatcc aattcatacc ccgttggcgc ttgagtttct accagctgat
    58981 atgctcctgg tgctaagcca tctatcgcca gttttccatc tgctcctgtg gttagacctg
    59041 actgcagaac ggttccattg gcatcttgta actcaaaaac agctccttgc aggacttctc
    59101 cgctttggtc atcgatcttt gtcaacacga caccgcctgg tgtaagtcga ttttctttcg
    59161 tcaattctac caccgctgtc tgacttcttt cgatctcaaa ctcgattggt gtcgcatcca
    59221 attcataccc cgttggcgct tgggtttcta ccagctgata cactcctggt gctaagccgt
    59281 caatcgccag ttttccatct gctcctgtgg ttagacctga ctgcagaacg gttccattgg
    59341 catcttgtaa ctcaaaaaca gctccttgca ggacttcccc gctttggtca tcgatctttg
    59401 tcaacacgac accgcctggt gtaagtcggt ttgctttcgt caattctacc accgctgtct
    59461 gacttctttc gatctcaaac tcgatcggtg tcgcatctaa ttcatacccc
//
LOCUS       DAJSMK010000009        52879 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.009, whole genome shotgun sequence.
ACCESSION   DAJSMK010000009 DAJSMK010000000
VERSION     DAJSMK010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52879)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52879)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52879
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.009"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(117..1166)
                     /gene="recA"
                     /locus_tag="ON488_000554"
     CDS             complement(117..1166)
                     /gene="recA"
                     /locus_tag="ON488_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HCR3230773.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(1275..2516)
                     /locus_tag="ON488_000555"
     CDS             complement(1275..2516)
                     /locus_tag="ON488_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HCR3230774.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(2756..3334)
                     /gene="pgsA"
                     /locus_tag="ON488_000556"
     CDS             complement(2756..3334)
                     /gene="pgsA"
                     /locus_tag="ON488_000556"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HCR3230775.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(3543..4466)
                     /locus_tag="ON488_000557"
     CDS             complement(3543..4466)
                     /locus_tag="ON488_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3230776.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(5205..6491)
                     /locus_tag="ON488_000558"
     CDS             complement(5205..6491)
                     /locus_tag="ON488_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCR3230777.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(6484..7752)
                     /locus_tag="ON488_000559"
     CDS             complement(6484..7752)
                     /locus_tag="ON488_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HCR3230778.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            8004..8465
                     /gene="mscL"
                     /locus_tag="ON488_000560"
     CDS             8004..8465
                     /gene="mscL"
                     /locus_tag="ON488_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HCR3230779.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(8524..8970)
                     /locus_tag="ON488_000561"
     CDS             complement(8524..8970)
                     /locus_tag="ON488_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3230780.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(9063..9308)
                     /locus_tag="ON488_000562"
     CDS             complement(9063..9308)
                     /locus_tag="ON488_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HCR3230781.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(9423..10001)
                     /locus_tag="ON488_000563"
     CDS             complement(9423..10001)
                     /locus_tag="ON488_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCR3230782.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(10078..10608)
                     /locus_tag="ON488_000564"
     CDS             complement(10078..10608)
                     /locus_tag="ON488_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HCR3230783.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(10612..11472)
                     /gene="rlmB"
                     /locus_tag="ON488_000565"
     CDS             complement(10612..11472)
                     /gene="rlmB"
                     /locus_tag="ON488_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HCR3230784.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(11465..11860)
                     /locus_tag="ON488_000566"
     CDS             complement(11465..11860)
                     /locus_tag="ON488_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HCR3230785.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(11857..13269)
                     /locus_tag="ON488_000567"
     CDS             complement(11857..13269)
                     /locus_tag="ON488_000567"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HCR3230786.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(13266..13802)
                     /gene="cysE"
                     /locus_tag="ON488_000568"
     CDS             complement(13266..13802)
                     /gene="cysE"
                     /locus_tag="ON488_000568"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HCR3230787.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(13888..14127)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14124..15584)
                     /locus_tag="ON488_000569"
     CDS             complement(14124..15584)
                     /locus_tag="ON488_000569"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HCR3230788.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(15754..16911)
                     /locus_tag="ON488_000570"
     CDS             complement(15754..16911)
                     /locus_tag="ON488_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HCR3230789.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(16945..18315)
                     /gene="radA"
                     /locus_tag="ON488_000571"
     CDS             complement(16945..18315)
                     /gene="radA"
                     /locus_tag="ON488_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HCR3230790.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(18378..18905)
                     /locus_tag="ON488_000572"
     CDS             complement(18378..18905)
                     /locus_tag="ON488_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HCR3230791.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
     gene            19135..19941
                     /gene="proB"
                     /locus_tag="ON488_000573"
     CDS             19135..19941
                     /gene="proB"
                     /locus_tag="ON488_000573"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HCR3230792.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            19938..21185
                     /locus_tag="ON488_000574"
     CDS             19938..21185
                     /locus_tag="ON488_000574"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HCR3230793.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            21261..21605
                     /locus_tag="ON488_000575"
     CDS             21261..21605
                     /locus_tag="ON488_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230794.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(21722..22048)
                     /locus_tag="ON488_000576"
     CDS             complement(21722..22048)
                     /locus_tag="ON488_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230795.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(22421..23622)
                     /locus_tag="ON488_000577"
                     /pseudo
     CDS             complement(22421..23622)
                     /locus_tag="ON488_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            23739..24254
                     /locus_tag="ON488_000578"
     CDS             23739..24254
                     /locus_tag="ON488_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCR3230796.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(24453..24899)
                     /locus_tag="ON488_000579"
     CDS             complement(24453..24899)
                     /locus_tag="ON488_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCR3230797.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(24946..26424)
                     /gene="msr(C)"
                     /locus_tag="ON488_000580"
     CDS             complement(24946..26424)
                     /gene="msr(C)"
                     /locus_tag="ON488_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCR3230798.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(26778..27407)
                     /locus_tag="ON488_000581"
     CDS             complement(26778..27407)
                     /locus_tag="ON488_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCR3230799.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(27391..27855)
                     /locus_tag="ON488_000582"
     CDS             complement(27391..27855)
                     /locus_tag="ON488_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3230800.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(28342..29610)
                     /locus_tag="ON488_000583"
     CDS             complement(28342..29610)
                     /locus_tag="ON488_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCR3230801.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(29841..30578)
                     /locus_tag="ON488_000584"
     CDS             complement(29841..30578)
                     /locus_tag="ON488_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3230802.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(30645..31214)
                     /locus_tag="ON488_000585"
     CDS             complement(30645..31214)
                     /locus_tag="ON488_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCR3230803.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            31342..32214
                     /locus_tag="ON488_000586"
     CDS             31342..32214
                     /locus_tag="ON488_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR3230804.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            32556..33428
                     /locus_tag="ON488_000587"
     CDS             32556..33428
                     /locus_tag="ON488_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3230805.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            33425..35383
                     /locus_tag="ON488_000588"
     CDS             33425..35383
                     /locus_tag="ON488_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3230806.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(35634..36485)
                     /locus_tag="ON488_000589"
     CDS             complement(35634..36485)
                     /locus_tag="ON488_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3230807.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            36608..37075
                     /locus_tag="ON488_000590"
     CDS             36608..37075
                     /locus_tag="ON488_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCR3230808.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(37338..37820)
                     /locus_tag="ON488_000591"
     CDS             complement(37338..37820)
                     /locus_tag="ON488_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCR3230809.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(37920..38783)
                     /locus_tag="ON488_000592"
     CDS             complement(37920..38783)
                     /locus_tag="ON488_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR3230810.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            39381..40229
                     /locus_tag="ON488_000593"
     CDS             39381..40229
                     /locus_tag="ON488_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230811.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(40400..40741)
                     /locus_tag="ON488_000594"
     CDS             complement(40400..40741)
                     /locus_tag="ON488_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCR3230812.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            40827..41534
                     /locus_tag="ON488_000595"
     CDS             40827..41534
                     /locus_tag="ON488_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCR3230813.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            41521..41844
                     /locus_tag="ON488_000596"
     CDS             41521..41844
                     /locus_tag="ON488_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCR3230814.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(41933..42970)
                     /locus_tag="ON488_000597"
     CDS             complement(41933..42970)
                     /locus_tag="ON488_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCR3230815.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(43417..44400)
                     /locus_tag="ON488_000598"
     CDS             complement(43417..44400)
                     /locus_tag="ON488_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HCR3230816.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(44816..45586)
                     /locus_tag="ON488_000599"
     CDS             complement(44816..45586)
                     /locus_tag="ON488_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230817.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(45579..46514)
                     /locus_tag="ON488_000600"
     CDS             complement(45579..46514)
                     /locus_tag="ON488_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230818.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(47108..48757)
                     /locus_tag="ON488_000601"
     CDS             complement(47108..48757)
                     /locus_tag="ON488_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCR3230819.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(48952..49848)
                     /locus_tag="ON488_000602"
     CDS             complement(48952..49848)
                     /locus_tag="ON488_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCR3230820.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(49841..50521)
                     /locus_tag="ON488_000603"
     CDS             complement(49841..50521)
                     /locus_tag="ON488_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3230821.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(50522..51304)
                     /locus_tag="ON488_000604"
     CDS             complement(50522..51304)
                     /locus_tag="ON488_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230822.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(51297..52214)
                     /locus_tag="ON488_000605"
     CDS             complement(51297..52214)
                     /locus_tag="ON488_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3230823.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(52217..52501)
                     /locus_tag="ON488_000606"
     CDS             complement(52217..52501)
                     /locus_tag="ON488_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230824.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
BASE COUNT        15152 a        11294 c         9458 g        16975 t
ORIGIN      
        1 ttttatgtac ccactcgtat aattaaataa ctcacgattt ctttattcaa taaaaaaacg
       61 gcaggtcaag gagagtacct actcttcaga ccagccgttt ttgtttatca taatttttat
      121 tcttctacta aaggcaattc ttcttgtcct ttttcatctt ctgggacagc gacttcttca
      181 ccaataccat aagctgctct aactagagca gaaacttctg ccatcatttc aggatgatta
      241 gccatataga ttttagcgtt ttcccgtcct tgaccaatcc gatcttcttt ataagaatac
      301 caagcaccgc ttttatcaac aatgtctttt tctactgcca tgtctagaag ttctccttct
      361 tgtgagatcc ctaaaccata catgacatct acttcagcga ttttgaaagg aggtgctact
      421 ttgtttttta cgactttgat ctttgtacgg ttaccaacaa tatctgtacc ttgtttcaat
      481 tgttctgcac gacgtacttc caaacggatc gttgcgtaga atttcaatgc gcgtcctcca
      541 ggagtgattt ctggattccc aaacatcacg cctacttttt cacggatttg gttgatgaaa
      601 atagcgattg tttttgtttt gttgatcgaa ccagagagtt tacgcaatgc ttgagacatc
      661 aaacgtgctt gtaacccgac atgtgagtca cccatttcgc cgtcgatttc tgctcgtgga
      721 actaaagcag caactgaatc gactactacg atatctacag ccccacttga tactaaagca
      781 tcagcgatct ctagaccttg ttctcctgtg tcaggctgtg aaagaagtag ttcatcgata
      841 ttcacaccta atttttgtgc atattgcgga tctaacgcat gctcagcatc aatgaaagcg
      901 gccgttccgc catttttttg tacttctgca atagcgtgta gtgcaactgt tgttttacct
      961 gaactttcag gtccatatac ttcgatgata cgtccacggg ggtaaccgcc gacacctaaa
     1021 gcgacatcta acgcaagaga gccacttgga attgtagaga tttgttggtc gattttttcg
     1081 cccaatttca taatagagcc tttaccatag ctcttttcaa tttttttcag tgcagcatct
     1141 aaggctgctt tacgatcatc tgccaatacg ataatcctcc ttatatttac aaatcagagc
     1201 aacatttcat tatccttatc atatcttttt tagtgaaaaa aagcaagaaa aaaccgaaca
     1261 aatattcgca tttatcattt tcttaaaagc tgttttctca aaagatcaaa tccttgcata
     1321 accgcattat atctgatagc agcacgatct ctggcaaagt gatatttttc cgaaaccacg
     1381 ccgtctttag atgaaatagc gatccatact gttcctgcag attgaccttc taacgtgtcc
     1441 ggtccagcca ctccggtgaa agctacactg taatctgttc ttgctatctc acgtgcttga
     1501 atggccatct gctccacaca ttctttgctg actgttccat attctgctaa tagctccgga
     1561 tcaatctcca gaaaaccagc ttttgtttgg agcgagtagg taacgaatcc gcctggaaat
     1621 acttcagata caccagcaat gtcgcctaat gcggcttgga aggcgccggc tgtcaaactt
     1681 tccgctgctg ttacagtctg cttgttttct ttcagtagtt ccactacgac ttttgctagc
     1741 gaattatcat cgccgtatcc ataaaaatat tcccctactc gttcttggat tttttcttct
     1801 aatgctaaaa gagcttgatt ccctgcctga acatcatttg ttttcactgt cagtcgtaat
     1861 gtcacttcat ttggtttggc atatggtgcg atcgttggat tgatctgtgt ctcaatcaga
     1921 tcttttagct cagtgaccag tcgcgattca ccaatcccat aaaagcgcaa aactttagaa
     1981 attagttttt cttcagaagg aaaacgttcc tctagtaaag gacgtacttg ttccacaaac
     2041 attggtttca actcattagg cggaccggga agaaggatat acgcatgtgt atctgtttga
     2101 taaaaagtcc ctaaagcaag ccctgtacga tttggtagag gaaccccgcc ttcgataatc
     2161 tgggactgtt gcagattgtt tttggtcatt tttcgatggg ttgtttcaaa atatgccaat
     2221 aattttttgt atccttccgt attttgtatg agagacttac cgaggtgagc cgcagttgct
     2281 tcttttgtca ggtcatcttc tgtcggtcct aatccgccac ataagagtat gagttcactt
     2341 cttgtttcag ctagagcaat caactcttct aaacgctgct gattatctcc tacaactgtt
     2401 tgataataaa cttcgatacc tagatcagct agctgttctg acaagaaagt ggcattcgta
     2461 ttcacgactt gtcctagtaa aagttctgtt ccgacagcta ttatttctgc tttcattact
     2521 tcccgctccc ttatatagta tacgctgtat ttttatattt ttttatttaa aaagagggca
     2581 aggagctgtg acaaaaatct tgtcacagct ccttgttcca aataaacagt gttctcctgc
     2641 caaaacctcg gtcataagtc acaatataca taaaacatga aaagctgttt tttgaaatta
     2701 tcccttgtga ctcagagtta gacggcaggc tcacaacctc tccactaaac gatacttaca
     2761 ttgatccttt gaacacaccg ctgtttttga tgaagtaatc cacacctgaa tagatagtaa
     2821 agatcagaca agcataaagc atgatttgat ctactggaat accgatcagg ctgaatggga
     2881 tattattgat aaacagcaag ataatagcaa ccatttgtgt agccgtcttg acttttcccg
     2941 gccaagctgc agccatgact tctccatgtt cgacaagtag taaacgcaag cctgtgacgg
     3001 ctaattcacg acagacaatg atcgctacta cccaaccagg ggcctttcct tggtcaacca
     3061 acatgataaa agcagtcata actagcattt tatctgccaa cgggtccgca aacttgccaa
     3121 aattagtgac aaggcctcgc gcacgggcaa tttttccatc taaccagtct gtgatactag
     3181 ctaaagcaaa aataactgca cctactagct gtgtgacagc cagtgtggtg tctcctacgt
     3241 taaattgtcc ccaatctaaa ggtaaaccta caaccaaaat gaaaatcggg atcatacaaa
     3301 ttctaagtac agttaattta tttggtaaat tcacactatc gactcctttc ttccctattc
     3361 tacgtgacta tcagcgaagt ttccaccgat attatttact tttccaaatg aatttattca
     3421 aaggagtatt tttattgaaa ttgatctttt tgaattaacg aagaaggacc gcgacacaga
     3481 tttgtcacga tccttctttt ttatacctac aagtaaacag atgcgtaaac taatttatac
     3541 gatcattctg cgtattgaag agtaaggttc acattttttg gactctgatt gttttcccct
     3601 ggattaactg gtacggattc tccattcgct ttgatcgttg cattgcttgc tgcaccaatc
     3661 gtgatggtcg catttgttgc tgtttccggt aacacggtac tctgtgtttc atttgctgcc
     3721 agtgtccctt gataaacata ggcattgtct actagcacac ctaaccatac acgattgaca
     3781 gcagtaaatt caagggttac aggcttggta gcgtctgtga tatttactgc gatggcactg
     3841 ccagaatctt ctcctgtagc tattgccatt ttcttttctt cacttgattt tgttgttgat
     3901 tctactgtag aagactcttt ggtctgcgtg ctttgctctg aggaagagga ctcctcgact
     3961 gatccttcta ctttaagcga agaagctgtg tctccgatta ttggatcagc ttgacgatct
     4021 tgccaagtca tatagcccac gacaacgaca atcgccaaag caaccaatcc taataaaatg
     4081 acaggaagac ttgtccaaaa gcgacttgga tgcgattctt cctgatgcat tgcttttcta
     4141 gaagtactta ctgtttcagg ctgcggacgt tcagggaccg atcctgtcaa tttgcttttc
     4201 ccatcaaaaa catcgactaa atggtctcca tcttctccta cagcttcagc gtattgccga
     4261 ataaatgccc gcacgtaaaa tttaccaggc aattggtcaa aatcatcatt gtcgattgct
     4321 tccaaataac gtttttgaat ttttgtaatc tgctgtaatt catctaaaga tattttttta
     4381 ttcaggcgtg cttgccgtaa tttttctccg atggtttcaa aagccactcg ttcatcttct
     4441 ccagtctgtt tgattctccg aagcatctgc tgttgcaacg aaagacgtta tgtttgggtg
     4501 ctgtgacaaa agtcatgtca cagctccttt tttccgaata aacattgttc tcctgccaac
     4561 tcctcggtca caagtcacaa tatccaataa atataagaag ctgttttttg aacttgttcc
     4621 ttgtgactcg gagttaaacg gcaggctcac gacctctttc ttaaacggtg ttcaatcagc
     4681 tgttcctcgg tattagctca aaaaccggca aaatataagg agatattttt ccgtatgttt
     4741 ctctaatact caggtcaaaa cgctgatttc acaacctctt ccttaaacgg tgttcaaaag
     4801 cttgcatctg cggtaataag tccaaccaag ttaaaaacat taagaagctg tttttacttg
     4861 gctgttctta ttacttgatg cagggcagct ttttcacaac ctcttggtac acggtgttcc
     4921 agaagtagct tcttcggcaa taagccgaaa tatcacaaaa atttgagaag caattttcgt
     4981 aaattccttc ttatttcttg aagctgacca cttctgtcac aacctctttg attacttcgt
     5041 ttgattttat tttaatataa gttgattaaa agagagcatg atttgtttta ttttctcact
     5101 aatttttcca acacaactaa gaataccata aaagctgatt ttggaggagg ttcctactac
     5161 aagtctaaaa cgaaatttaa gacttttcct cataaaatac tggtttattt tggtctcatg
     5221 taaaactcgc tgaaggcctc ttcacttata aatgcttccc cagctgccag tacgtctttc
     5281 atttggatcg aatcgatgat ttcaggaaga tcaaataaag ttcgatcgcc aaataaactt
     5341 tgcgtaaatt gattggcaat atattcgatc gaatttaatg attggaaata ttgtccaagc
     5401 attttcttct tcagcaaatc gagatttgtt tctgacactt ccggatcatc agcgaatcca
     5461 agaatgattt ctttgacttt ttctgctgct ttctctggtt cgtccgtatc tccgctgaag
     5521 tccgcaaagt gaaattcacg atccaagctg aattcaaaac caaagctgtc atcgataatt
     5581 ccttgattgt acatcgctag atagtttcga gaagtattgc ctaaaatcat ttggaacaac
     5641 agattgattg ctgttttata gcgtaacagt tctgttcctt cttgcggcaa tgtgtctaat
     5701 cctttaatac caagtacaaa tttatctcgt gtaatggctg cttccaatgc actttgtttg
     5761 atgatttctt ttgtgttttc agggaaataa cgtacaattt cttgctttgg agggaaattt
     5821 tttgcttctt ggttttcccg aataagtttc atcaatttct caggctccat cttaccaact
     5881 acaaataaaa ccatattgct tggctgataa aacgtccgat agcacgtata caagtcttga
     5941 gctgtgattt tgtcgatact ttcaaccgtg cccgcaatat cgatatgcaa tgggtgtgta
     6001 ggatacaagt tatttagtat gccaaaaaac atccgccagt tagggtcgtc ttcatacatt
     6061 tggatttcct gaccgatgat tcctttttcc ttgtttacag tttcttctgt gaagtaaggt
     6121 gcttgtacaa aatcgatcag agtcgtcaga ttcttttcta cctgatccgt cgtagaaaac
     6181 agatagctgg ttttcgtaaa acttgtgaaa gcattggcgg aagctccttg tttcccaaat
     6241 aattgaaaga catcaccatc ttctttttca aacaacttat gttctaaaaa atgggcaatt
     6301 ccatctggaa ctttcacctt ttctttttca ccatagggaa taaattcgtt atcgatcgaa
     6361 ccataattcg tactgaacaa accatatgtc ttgtgatagt catttttagg caacaaatac
     6421 acggtcaaac cgtttggcag tacttcatga taaagtgttt cattgatttg ctcatattct
     6481 gttttattca tttgcatttc ctcctgctaa aaagaagatt gcctgcaatt cgatttgctc
     6541 agctacttgt tgtatctctt tgatcgttac gctctccata cgtttcaacc attcttcatc
     6601 agataatttt gtttccggca gccagctgtc caaaaaagaa gcttcgattg ccgcttgcgg
     6661 agagtctaga gaaagcagat attggtttct cagcattgct tttgtctgag acagttccaa
     6721 ctctgttatt tcaccatttc gcaaactttc taattgctcg tgaatcagat gaagtacttg
     6781 atttcggttc ttttcatcga taccggtttg gacactcatg aatcctcgga acgtatccac
     6841 gctactagag gcataataag ctagactttc tttctctctg acattcatga aaagtttaga
     6901 gtgaggaaaa ccgccaaata aaccgttaaa gaccattagc gcaaaacgtt ctggttcatc
     6961 gtaatacaca tttgtctgat aagctaggtt cagctttgct tgaacgattg gctcacgtac
     7021 ttgtcgttcc ttcacgatat tcacttgagg ttgggtataa aacagatctg gataaactgt
     7081 ttcccgcgac tcaaatggta attgcccaac tgcttcagct gctttgtccg gatcaacatc
     7141 gccgacaaca aaaatgtcga tttgatcatt tgccatcatt tcttgatagt aggacgctag
     7201 cgaactagca gtgatcttgt ccaaatcttc gactacgccc aaccctggga tcttttgttc
     7261 cgggctgttt tcaaaataaa gttcttgcaa ggcataggaa gcaaaagttt gtttatcttc
     7321 cttcaaactt tccaaatata gacgcagatt gttcttttcc aagtcaaacg tcaactgatc
     7381 aaactgatga tttttaatat ttggataaaa taaaacctct tttaaaaaat ctaccgcttg
     7441 agaaaaaagg tttggatcat tgacatattc accattcaca aaactgatcc ctgcgtttag
     7501 ccaatgtaaa tttccttttt ttctaactga taatccaaag cttgcgccat aaagctctgc
     7561 aagttgcgca cttaactttg tctgatccgg ataattcaaa ctatttgttt ccaacatgct
     7621 gctgagaagt gaacgtttcg tgatgacttc ttgttgcaga cgcgcagtaa aacggataaa
     7681 aatccggatc gttttgtatt gttttgttgg taagacatga agattcacgc cttctgccaa
     7741 ttgatacacc atatttatat gctccttttc acagttgatt gcccgcttac tcttttaatg
     7801 ggtcaacctg ccttttttac ttattcctct gcttgaaatt tataagttca ggcaattcgc
     7861 cgttttttct aaatgatgtt acactttata gtatagcata gatgtttttt atcaaaagaa
     7921 acagacggct aaaagcgtat attgtttttt tattttttat ttttcgatat actaaagaca
     7981 aataaaagaa gggagggtca ttcatgatca aagaattcaa agagttcatc atgcgtggag
     8041 atgtcttgga tcttgctgtc ggcgttgtta ttggtagtgc gtttacaagc atcgtaaacc
     8101 aagtggtgca aggcttgatc acaccactaa taggttggtt tgtcgcaatg atcacaggta
     8161 cttctgattt agaaggagca ctttcaattc ttgactggtc gccgacaaaa ggcgtcacat
     8221 ttgcgtttgg taacgttatt agtgctatca ttacatttct gatcactggt tttgtcttat
     8281 tcttagttgt caaagcggca aaccgtgcga agaatttacg ctccaaagaa gagcaagtgg
     8341 aagtggaaga aactcctact gcagaagatt atcttagtga catacgcgat cttcttgcca
     8401 aacaagtggc agaagacaat acacatccag tagagcaaac aaatctttcc gatacttcta
     8461 aataataaag aatctaaaaa aaagaaagcc gattttcagt gtcggctttc tttttttaga
     8521 ttcttaactt gctacttgtt cctttttcat gtcgatatgt ggaatatcat cttccaaata
     8581 cacatctgag attgccttga atccaaacga ctcataaaaa gcttgtaggt attcttgtgc
     8641 gccgatcacg attggttttt ctggaaaatt tttctggatc atgttaatcg tttcttgaac
     8701 aatctttctt cctaaaccat ctttacggtt gtcctgatga acaaggacac gtccaaaatg
     8761 gatactctcc gcttcttcat atactcgcgt gtaggcaagg atcttcccat cagtatcttg
     8821 aaaaaacgta tgccaagctt gtccatcaat gtcatcaact tcttgataag gacactgttg
     8881 ttccacaaca aaaactgcga ttcgttcttt gacgatcgcg taaaactctg ctgttgacaa
     8941 ttcttcaaat ttctttacct gatattccac taagcaaacg ccccctgctt ttttattctt
     9001 agcataccga ttcgcacaca aaaaagcaaa cgaaccttac gaatctcagg ctcgtttgct
     9061 ttttaaactg cttcagttaa aaattcgatc tcaactgtcc gagtaagtac atctgaatag
     9121 ctgtaagata ctcgttcaaa agaattttct tcaggatcca aatcaacaac gaatactgaa
     9181 ggataggttt ctgttaaaac gccgcggcgt tctgtttgac gctttcttcc tgtctgagca
     9241 accaacatga ttgggctgcc gatacgacct tctaaatctt tcttgattga agctaaagtt
     9301 gttggcatac agttcacctc tactatcaac tataccacat atttttaaaa ttttcaagtt
     9361 taccataaaa aaaaaagaaa tgcaataaaa ataaataaga agctcattaa gatttttcta
     9421 aattattcct cattataaaa tttcaagtgt ttttttattt tgagttttac tctcccgtaa
     9481 gcgctcatta cttgcttgtg atccattgct aaacattcag ccatgtctac aaaatcaacg
     9541 ccttgcatat aataatgaaa aattttagct tctatttttg aaaactggat ttcgcaattt
     9601 tcgattgctt cttttaataa aagatgctga atcgctaaag gttcttgcaa tgtgatctct
     9661 gctaaaaagt ctggtccttc tgtctctatt ttttggtcga ttgagacttc atctttttga
     9721 tcacgacgct tcagcgcgtt ctgcttcctc aacagagaat agatttgatt gcttataatg
     9781 cttttataat aacttccaaa gctaacacct ttgctttttt cgtaagttct caatgcctga
     9841 tataaagcga tccttgcttc ttgttcccaa tcctcagaaa cataatttct taaataatag
     9901 gtgtttttca aacgtagtaa aagtggaaaa tatttttgat acagggcagc aaatgcttct
     9961 tcgtcaccat tacgtgcagc gcgcaataac tcctcagaca taaaataatt cctccataaa
    10021 ttcgtttatg gaggaatctt atcatcaatg attcatcgaa ctgattagaa cgatatgtta
    10081 tttatttttt ctcattaaat cgtccaattt ttgggacaat ttttttaact gctcttcatt
    10141 ccatggagaa ttacgtcgga aatcaataaa atgcatatct ttattttctt gggctattgt
    10201 tttttccgtt ttttttatcg tcttatataa ttcataagca gaagttcgta atgctccttg
    10261 ggaaaagatc atccactgtt ctgctaaatc gcttgtcgcc actgtcactt gtgtcaaacg
    10321 gtcattcagc tgaccagcga ttctctcgat ataactgtca gccgtttcgt cttctttcgt
    10381 aaaaacaaca tccaactggt atttcttata attttgttgg atgcccggaa ctagttgggc
    10441 atcgaagaca acgatgactt ccattccttc atatttcgca taatttgata aacgatgtaa
    10501 aagagcttct cttgcatccg ccattttgtc ctgcttttta agctggacaa gttccggcca
    10561 cgaaccaatc atgttgtagc cgtctacaat caacagctgt tttttcatgg tctactcccc
    10621 ctgacgttgg gaaaaagcct gatacataag caaaccagca gcaacactgg catttaagct
    10681 ctggacgtgc ccggtcatcg ggatcgtcag caattcatcc atttcttttt tcaatcctgg
    10741 actcattcct ttgccttcat taccaatgac taaagcaatt gatcctttgg cattccattt
    10801 ttggaagttt gtgccggtca tatctgtgcc aaatacccaa aatcctgttt ctttgagctg
    10861 ttgcacagct tgtaccaaat tcgtcacgcg tgcaacaggg acatgttcga ctgccccagt
    10921 ggaagtcttt gttacgatag gtgtgattcc aactgctcgg tgttttggta tgatcacacc
    10981 atcgacgcca cttgcgtctg ctgtccgtaa aatcgaccca aaattgtgtg gatcttcgat
    11041 gctatccaaa atcaaaaaga aggggtcttc ttttttctct tttgttcgtt caatcagttg
    11101 gtcaagggat aaatattcat aaggtgtaat cgcaagaacg actccttgat gcacgccgtg
    11161 atcgctcaaa gtttctaatt tttgtttagg aacccatttg actggcacag cttgttcacg
    11221 tgcgatttct ttcagttctt ctactttttc tcctcgtgaa tcttcttgaa gaaagagttt
    11281 attccctcgc ccttgttgta gcgcttctac tgcggcatgg tgcccaaaga cgaaattatc
    11341 ttctaatgct tcttcatttt gatcagaaac tgactgattt cgtccagttt gctttttatt
    11401 tgaatatcta ttttgttttt tgtcttcaaa tccacgtttc gattgatgtt tgtttgttct
    11461 ttctttaccc atttttttca ccaactttct gaatacacca gcggatcaat tcttccatcc
    11521 gctcggtttg ttttgtcaaa tgcagatagc ccatgagcgc ttcgaaccct gttgcgaccc
    11581 gatacgtcgt aacatcagca ttttttgcgc tcgtatggct tttagcattt cttcctctgc
    11641 gataataaag ttcttcttct tctgtcaaaa gatgttcttc cagcatttgc tgaatcaaaa
    11701 aggcttgtgc attcgcagaa acataattcg ttgccgcacg atgcagctta ttgggttttg
    11761 tttctccttg atcaatcagg tggtcacgaa catagatttc gtaaatcgca tctccaacat
    11821 aagccaaggc taaaccgttc aattgtgtgt aatctctcat gcttctcttc tccatcgggt
    11881 tccttgcggt gtatcttcta ataagatccc tttttctttc aacaaatcac gaatttcgtc
    11941 gcttcggaca aaatcacgat tgcttcttgc ttgatttcgt tcttcgatca attgttcaat
    12001 ctcttcatct aataactctt ctgctgtaaa taaaataccg aagatcgaaa gccattgcga
    12061 gaataaagct tctccttgtg ccaagacagc ggcagaaact ttcggctggt ctagataagt
    12121 gttcagccac ttagcaagct catagaccac tgtgatccca tttgctgcat taaaatcatc
    12181 gtccatttct tcgatgaatc gctgttctaa attttctaac aaagcgattt tatccgcatc
    12241 atctgccaaa ttctctgagg cagtttcttg gcggaatttc aaattgtcaa acgtattctt
    12301 cagtcgttgt aaattggtgg ctgcttcttt catcgtcgtt tcactgtagc ggatcggacg
    12361 acggtattgt gtggtcgcca tgaagaaacg caagacttgt ggatcaacgt ttttgatcat
    12421 ttcatgtaca gtgatgaaat tccctagaga tttactcatt ttttcatcgt cttcgccaat
    12481 cgttacatag ccattgtgca tccagtaatt agcgaatttt ttccctgttt tcgcttcact
    12541 ttgtgcgatt tcattttcat gatgaggaaa ttctaaatct tgcccgccac catggatatc
    12601 gatcgtttct cctaaatgtt ttgttgccat aacggaacat tcaatatgcc aaccgggacg
    12661 tcctttgccc catggtgaat cccaagaaat ctcgccaggt tttgcttgtt tccataaagc
    12721 gaaatctaat gggtcttctt tttgctgctg ttcttcccct gtacgctgac ttgctccgac
    12781 ttccagttca tcgatggatt ggtcacttaa tttcccataa ttttcaaatt tacgggtacg
    12841 gtaatacaca tcacctgaag attcataagc atagcctttt tcaaccaaca cttgaataaa
    12901 tgctaaaata tctggcatat gatccatgac tcttggatgc agtgtagcag gctcgacatt
    12961 caacgctttc gtatcttctt caaatgctcg gatgaaacga tcagcaactt ctggtgctgt
    13021 aatacctaat tcgtttgctg tacggatgat tttatcgtct acatccgtga aattcgatac
    13081 gaaatcgact ttatagcctc gatattcaaa atagcgtcga attgtatcga aagcaatggt
    13141 gctacgagca tttccgatat ggatataatt atacacagtc ggtccgcaga catacatacc
    13201 gacatgtccc ttttgtatag ggatgaattc ttcttttttt ctggtcaatg tattgtagat
    13261 ttttatcatt ctgatctcct cactttttct cctttgattc gaacgacttt tgctggtact
    13321 cctaccgctg tagcgtcgtc tggaacatct ttcaacacaa cggcacctgc accgattttg
    13381 gcgttttttc cgatcgttac cggtcctaat atctgcgcat tcgcagagag catggctcct
    13441 tgtttaacag ttgggtgtct tttacccgtt tcttttcctg tgccgcctaa tgttacgcca
    13501 tggaataaaa tcacatcgtc ctcgatttct gcggtttcgc caatgacgat tcccattcca
    13561 tggtcgatga acacgccagt tccaatcgtt gctcctggat ggatctcaac accagttagg
    13621 aaacgccaga attgagcatt gatcttcgcc aataaaaaga gccggtgctg atataaaaaa
    13681 tgagagaaac gatgccaaaa caaggcatga aaaccagggt atgtcaaaac gatctcagct
    13741 gtcgaacgtg cagccggatc gtttctcttt gctgcatcaa tcgctcgggt aaaccaactc
    13801 atgactttcc actcctttcg taagaatttt atgtaggaaa tcatcttctt ataaagaaaa
    13861 gaagcgcctt ttaaataagt ttccttatca aaagacgctt tccgcgtggt tccacttttc
    13921 ttcataatca atgattatct ctgacagcta acgcctgtta tacgttcttg gctactttgt
    13981 ttcctataaa acagtttttc ctgttttctg tgtttcgcca agaccactcc cagaggcatt
    14041 tcggcaacca ttcattgata ccttgcacca cccggtatct ctcttgtaat gatcagctgc
    14101 ttactttttt ctgttcatcg tgtttagttc agtacttgat ttaaatgtgc taatgatttt
    14161 tcacgaccaa gcaattcgat cgtttcaggc aattctggac catgcatttg tcctgataca
    14221 gctacacgga ttggcatgaa aagatttttt ccttttacgc cagtttcttt ttgaacagct
    14281 ttgatggcag ctttgacagt tggagcatct actacttcca tttgttctag ctgtgctttg
    14341 aatgcgtgga gaacagtagg aactgtttca ccagcaagta cttcttttgc tgcttcattc
    14401 aatacaggat gttcattgaa aaatagcgta gacagatcaa cgatttctgc agcatagctc
    14461 atttgaggtt gatacaggct aacgatcttc ttcacccatt cgattgtctt ttcatctggg
    14521 ttttctgcta cacgtccatc agcgattaga taaggcagac acatgtcagt aaatgcatct
    14581 agatccattg ctttgatgta atggttgttt acccattgca gttttttcgc atcgaaagct
    14641 gcgggtgatt tacttaggcg ttttggatcg aacattttga tcaattcttg gtgttcgaag
    14701 atttcgtctt cgcccacagg tgaccagccc aataatgcaa taaagttgaa cattgcatct
    14761 ggtagatagc ctaattcgcg atattgttcg ataaattgca agattgattc gtcacgtttg
    14821 cttagttttt tacctgtttc actgttgatg atcaatgtca tatgtccgaa ggttggtggt
    14881 gtccagccaa atgcttcata gatcatcagt tgttttggtg tattggcaat atggtcatct
    14941 ccacgtaaaa cgtgagtgat tttcatcaaa tgatcatcga ccgcaacagc aaaattataa
    15001 gttggcatac catcgcgttt ttgtatgaca aagtcgccac cgatattatc ggattcgaac
    15061 gaaatagcgc ctttcaccat atctgtaaat gcgtattctg tattgcgagg cacacggaaa
    15121 cgtacaacag attctagacc ttgtgcttct ttttctgctt gttcttcagg tgtcaagttc
    15181 gcacatgttc ctgcgtaatg aggcatttct cctcttgcgc gttgtgcttc ccgttctgct
    15241 tctaattctt cttctgtgca atagcatttg tatgctcgat tgctagcaag cagctgatca
    15301 atcagcggtt gatagatttc tttacgttca gattgacggt aagggccgta ttctccagga
    15361 ttttcaggag attcatccca attcattccc aaccaagcaa ggttttccaa ctggcttttt
    15421 tcgccatctt cgatattacg tttttggtca gtatcctcaa tacgaataat aaagtctcca
    15481 tcattgtggc gggcaaacaa ataattgaat aatgcagttc ttgcatttcc aatatgcagg
    15541 tgcccagttg gacttggtgc atagcgtacg cgtactttcg tcattttctt cctcttcttt
    15601 caaactagac tttgactaac agcaaaaatt ccgtcagtta cggcttctca aatatcattt
    15661 atttaaagcc actcagcaca aattttacct tttctaaggt aaatagtaaa gccaactggt
    15721 tgaatttcct taccagttgg ctgaatttct tttttatttt gattgtttag tctttttctc
    15781 tgtctctttt ttattgtcga ttcctcgtcc tgcatgtgca ggtttagcaa agatcatgcg
    15841 tccagcagct gtttgaaggg cacttgttac aacgacttcg atacgttcat tcatgtaatg
    15901 ctgtccatct tctacgacaa ccatcgtgcc gtcatcaagg taggctactc cttgttggcg
    15961 ttctgtcccg gcttttacta ctagaacatt catcgtttca ccagggatga cgactggttt
    16021 tacggcattt gccaacgcat tgatattaag aacaggtaca ttttggaatt cagagacttt
    16081 attcaagtta tagtcattgg ttacaatgac accatctaaa agcttagcca atttgatcaa
    16141 tttgctgtct acttcactga tatcttcaaa gtctccatcg tacatttcga cagatatacc
    16201 ctcttctttt tgcaaggcat ttaggatatc taatccgcga cgaccacgca cacgtttcaa
    16261 actatcccct gagtccgcga tgtattgtag ttcgtaaaga acaaaattag ggatcatcaa
    16321 ggttccttct aagaatccag tctttgtaat atcataaatc cgaccgtcaa tgatcacgct
    16381 tgtatccaag attttatatt tatggaaatt ttctcctgat tttcgttcta acagttgact
    16441 ctcaacttga ctagctgttt cttgctcgat ttttttgctt cgtgaaccaa aaactttctt
    16501 ccattcttcg attcgtgtcg ttcccattct caatcccaga tagcctaaga tgatcatcag
    16561 taaaatcggc aatacactat tgacgaatgg aatttccata ttgtaaagag gggtcgagat
    16621 cacaacacct aaagtcaatc cgatgatcgc accgatcgca ccgaagagaa gataagtcaa
    16681 gctgacctca cttagttttt gttctacttg tttgataata gctgagatat gtttggccaa
    16741 cagcaaagat aataaaaaga aaataagtgc gcctaacagg ctgttggtaa atgtattatt
    16801 cagccatccg tttgactgtt gaccgattgc ctgccaagct gagggtaaaa atgaaatacc
    16861 caagcttgcg ccgacaatga tcatcagcaa agtaatgaca cgtttttgca tcgtttttcc
    16921 tccgtttcga caatcattta ttagttagcg gaacacacgc ttcaacgttt cagccaaagt
    16981 tgctactcca actatctcga ttccttttgg cgcttcccag ttacctaagt tgtttttagg
    17041 taggtatact tttgtgaagc cgagtttttg gacttctttg actcgttgtt caatatgact
    17101 gacacgtctg atttctccag tcagtccaat ttcaccgatg aaacattccg ttggctgtgt
    17161 tcctttttct ttatagcttg aagcaatact gacagcgata gctaaatcaa tcgctggttc
    17221 atttaatttt accccacctg cagcttttaa gtaagcatct tgattctgaa gaagcaaccc
    17281 agctcttttt tccagcactg ccatgatcag agatacccga ttgaaatcaa gacctgttgt
    17341 tgttcgtttg gcatttccga acatagtagg tgtgactaat gcttggatct ctaccaaaat
    17401 tggacgtgtc ccttccattg ccacaacgat agcagagcca gttgcaccgt ctaggcgttc
    17461 ttctaagaaa atctgtgaag gattagcgac ttcttccaat ccatgctcat gcatttcaaa
    17521 aatcccaatc tcattcgttg agccaaatcg gttttttact gctcgcaaaa tccgaaaact
    17581 atgatgttgt tcaccttcaa aatataacac cgtatccacc atatgttcta acattcttgg
    17641 gccggcgatc gagccttctt tggtaacatg accgacgata aaaatggcta tcccatttgt
    17701 tttagcgatt ttgagtagtt ctgcagtggt ttctcttact tggctgacac ttcctgccac
    17761 acttgtgatg tctggctgcg tcatcgtttg gatggaatca atgataacat aatcagggga
    17821 gatatgttcg atggcacgac tgatttcgtt catatctgtt tcagcgtata gataaaattc
    17881 tgtgttgata cttccgaggc gttccgcgcg taattttatc tgctctgcgc tttcttcgcc
    17941 ggatacatat aagacttttc cgcctatggc tgctaattgc tgagaaactt gtaacagcaa
    18001 agtggatttc ccgatacctg gatcgccacc aatcaagacc atagaccctg gcaccacacc
    18061 tccgcctaac acacggttca gttcttctaa ttttgttttg atccgaggtt cttttttagg
    18121 gacgacgtct gcgatttttg ttggttttgc tttttctcct gtcaaacttg tccgagttct
    18181 gcggtccgtt gtatcttgtt cgatttcttc gaccatcgta ttccattttc cgcaatttgg
    18241 gcagcgtccc aagaacttag gcgacacata cccgcaattt tggcaaacaa attgtacttt
    18301 tgattttttt gccattgtac cgcctccttt tatcctaatc atgagacatt aaatcaagct
    18361 taagtatctt taacgtttta tttactggaa gaaccaaatc cgccttgacg ttgagcagtc
    18421 gtttgatctt gatctgcttt taaaaacggc aaaaagatcc cttggccgat acgctcgcct
    18481 tttttgatca ctacatcctt gaaaccaaag ttggtgaatt ggaacatgat atggccttca
    18541 tttgcctcat tattgtaata atcactgtca atcacaccta ctccgtttgt caacactaaa
    18601 aaccgcttca acggattgct tgaacggtta gcaagctgca aaaattcatc ttctcccatg
    18661 taagctttga ttccagtagg cacgagggtt ggtttcaatt gtttttcatt ttctgataca
    18721 tcttttttca atccatctgc gactgtttcc aacccctttt tccagcctgc tttccagata
    18781 cttggaatca cgacctcttc tgctgcttca aaatcatagc cagcagcatg atgtgtagcg
    18841 cgctgcggta gattgatatt ttgatcttta tatttagaaa taacttcaaa tcctcttttt
    18901 ctcaccggtt ttcctcccta aataaactac tcctattcta acatatccga ggctgtaaaa
    18961 gactttcttt acaaattctt caagaaattc tgctatctta aagtaaacca ttaattcgtt
    19021 ctttttccaa acgactgcaa gttgtacaaa aaaactattt tttacatgac tttactcgtc
    19081 aaaacaagta gaatagaacg aaattaatga gtggatattt gattgaggtg tcacatgcgt
    19141 aaagaaatta aaaatgcaaa acgaattatt gtcaaagtag gaacaagtac attgatttat
    19201 cccaatggaa atatcaatct tgcggcaatc gatcagttag cttttgtcct ttctgatctt
    19261 agaaatcggg gaaaggaagt gatcttagtc tcatcaggag ctgtaggcgt tggtatgcat
    19321 aaattacatt tgtcagaacg tccgactttg attcctgaac agcaagctgc ggcggctgtt
    19381 ggtcaagccg aactgatgaa tatctataat caaagattca gtgtatataa tcaacagacg
    19441 gcacagatcc tcgtgacaag agacgtggta gattatcctg aaagtcgtaa aaatgtgagg
    19501 aatacattgg aacagctttt gattatggac acgatcccta tcgtgaacga aaacgatact
    19561 gtagcagtgg atgaattaga tcatctgaca aaatttggcg ataatgatca gctgtcagcc
    19621 atcatggcaa aacttgtcgc ggcagacctt ttgatcgtcc tttctgatat cgacgggttt
    19681 tattcagata atccgactac aaatcccgag gctcagatgt atcgctatat cgataaaatc
    19741 gatgaaaaga ttctggcaca agcaggtggt gctggtagca catttggaac aggcggtatg
    19801 cagagtaaat taaaagccgc ttctaggata tttgaagcaa acagcgcaat gattttagca
    19861 aatggaaaaa atccggcaat tatttttgat attcttgcag gaaaagaagt aggtacttta
    19921 tttaaggagg acttgaaatg actgacttga tgcaattagg acaacaggca aaagatagcg
    19981 cgcaacaact agcacttatg cctacaaacc gcaaaaatga gctacttgtt caaatggcac
    20041 aaaccatcaa aaagaatcaa caagcgatca ttgaagcaaa tcataaagac ttagaaaaag
    20101 cagtcgaaaa caatatcagt gaaacgatgc aagaccgctt gcagctgaca cctgagcgaa
    20161 tcaatgccat ggctacagag atcgaaaaaa ttgcttcgtt agacgatcct attggaaaag
    20221 tagatgagat gtggacgaac accgacggat tgagaatcgg caaaaagcgc gtgccactag
    20281 gcgtgaccgg catcatttac gaatctcgtc caaatgtcac gacagatgca gctagtctag
    20341 cattcaaatc agggaatgcc gttatccttc gcggtggcaa agaagcattc ttctcgaatc
    20401 aattattagt ccaattattg cagcaagtac tggtcagtgc tggcgaatct ccttatgcca
    20461 tccagtttgt cgatgatact tctcatgaaa ctgcaggaca gttgatgcga ttgacagaat
    20521 acttagatgt gctgattcct cgaggcggag caaaattaat ccaacgagtc aaagaacagg
    20581 caacggtacc tatcattgaa acaggtacag gaaataatca cgtatatatc gataaagaag
    20641 cacagttatc tatggcagtg aacatcatcg tcaatgcaaa agcttcccgt ccatctgtct
    20701 gtaacgcggc agaaacattg ctgatccatt ctgagatcgc accttttttc ttgccagcta
    20761 ttgaaaaaga actggtagaa cacggggtct ctttacgtgc ggatgctcgt gcgttagaat
    20821 atctagagac ggctgcttta gcagaagaca cagattggga tactgaatat ctagattata
    20881 tccttgctgt caaagtggtc gattctttgg atgaagcaat tgcacatatc aatcggcata
    20941 atactaaaca ttcagaaacg atcgtgacag atagttatgc ggctagtcaa cgtttcttaa
    21001 atgaagtgga cgcggcggct gtctatgtca atgcctccac tcgttttaca gacggatcgg
    21061 tatttggttt tggtgcagag attggtatct ctactcaaaa gttgcatgcc cgtggtccaa
    21121 tggggttaaa tgaattaact tccacaaaat atatcattta tggcgatgga caaatccgcg
    21181 aataatgttt cgtgtgaaac attattcccg ccttttgcct tttttctgta aaggttctat
    21241 ccaactagaa aggtgtcaat atgtttgaaa ttttaatgat tttttttatt taccttattt
    21301 ctctgaatat cgctgctttt ctgggagtcg gtattttatc ccttttcttt caattcaaaa
    21361 aacgaagcat agggagtcaa cgggaaaaat ggtcgcagta ttttgacaaa atcgggcaaa
    21421 aagggctggt tacacgcttg cacattagtt acatggttgc attatgctta ttagcgacaa
    21481 tcaattacta ttcttttttc gatcattcaa tcgcttatac gattacgcta ctgattgctg
    21541 ggatttttca cttatcttat aaatatcagc tgaataaaaa ccacttgaat cggactttcc
    21601 gctaaaaaat atccgtacga taagtagagt gccttgaaga tcggcaaaaa actgccggac
    21661 tttttagagg ctgtgacaaa gattttgtca cagcctcttt ttccatataa acggcgttcg
    21721 cctaccagct gcctggtaaa tctgtttcct cttcgttaag aagcgaaaat ccgtcaaatg
    21781 tttcgccatc ataataacga agcagctcat ccatggacaa gttcatcgtt ttttcttttt
    21841 cttcttccgc tgattcagcc agtagctgtt cccgatacac ctgatacata ccagctattt
    21901 tttgctgcat cgcttttcta gtttcacctt ccgcattgat tattggcaat tctttgatat
    21961 agccacgata aatcaaccga tcatctgaaa attcaatggg taattcaacg agtgtcaacc
    22021 cgacttcctg aaaatattct tccagcatct attatccccc cattcttttt cttaaatgaa
    22081 ttttagctta cctactgaaa attttccagt ttcattattt tgagaaaaaa agggaatgtg
    22141 acaaaaatcg tgtcacatcc cctttttccg aataaatggt gttcttctgc caactcctca
    22201 atcataagtc acaatattca acaaacatga gaaactgttt tttgaaattg ttccttgtga
    22261 ttcagagtta aacgacagtc tcacaacctc ttggtaaacg gcgttcaaaa gcttgcatct
    22321 gcggtaataa gcccaaccaa acgaaaaata tgagaagcta tttttgtttg gctgttctta
    22381 tgacttgatg caggacagct ttttcacaac ctctgatttc ttattcttct tcatttgtag
    22441 caaaataatt acggtgataa atgatacaac atacactgat aagaacaatg gcacctgcaa
    22501 aataaaacgc atagctttca ccaatatgtt caccaatcac acctgcaata aatggtgcta
    22561 aagctccacc gaaaaagcgg acaaaactat agctggacga agcaacgttt cgttgcagac
    22621 ctggtatttc catagcaatc gtcgtcaaca gtgtattgat aattccttgg aaaaatcctg
    22681 ctaacacaat gctgatcggt acaaggactg gcatagaagt tccagctcct aataacagca
    22741 aacaaataat gaataagaca aatgctgcta aaattgtccg ataagtcgta aacttccgct
    22801 caagagccgg tgcaacgaaa atcgaagcaa tagccagaag cacaccccag ccaaaaaata
    22861 caaaaccgac ttctaattca gaatagccaa tcaataaaaa tggcgcatac gcaagtaaag
    22921 taaagaatcc gaaattatat aacaatgcga ttagtccaac tgaacgaagt ttatgattgc
    22981 ttaacgcttt gacaccttcc caaaggccta cttttctctt tggtttctca gtttcaggta
    23041 aaagtaccgc tagggctata aaaccgcaaa acatcaaaaa tgctacccca aaaaatggat
    23101 aacgccatga accactgccc aagaccccac cgactagagg gccaacagcc attccgcagc
    23161 caagtgctgc ttcatacatc atgattgctt tttctgtgtt accaactaaa atactgacga
    23221 tcgttgctaa agcagtagag acaaataaag cattcccgac accccagccg gcacgtaacc
    23281 caatcagcat tccgatattc ccagataatc cgccaagacc agcgaataca acgatgataa
    23341 acaatcctgt catcaatgtt ttttcaaacc gatccgacta gataagaaac ctgtaaatag
    23401 catcaccaca ccagtgacta acatgtaact agtaaataac agggtcgttt cagctggcgt
    23461 agcgtttaac tgtgcagcaa tcgtttttaa gattgggtct actagaccca ctcccataaa
    23521 agcgatcata caggtagctg ctacaactag cgctgaactt ttcccctttg tttcttcatt
    23581 tgtttgttct tgtatatcta tttgattctc caatatttcc atccctttct ctctattagc
    23641 atcatacatg atttatttta catgtaaata tgcacatgta aaacgtggaa actttactgt
    23701 gatataataa agaaaataag acgagaggta ggatttttat gaatacttta gcctatatat
    23761 tattatgcgt gcttttatcc aaaccacgtt ctgggtatga attgaagcag ctgatcacaa
    23821 ttttttggga agcccatcac agtcagatct atacaacgct tgccaagtta gaccagcagg
    23881 gttatgtgac cgttttggac aaagacgagc actctcaaaa aaagatctac cacttgactg
    23941 atgaaggacg tgctcttgta gaggaatgga tcaaagagga aactcccgct cctacgcaaa
    24001 aagatgaatt tctagcaaaa atctatgctt tttcgacgct cgataaaaca acagctactg
    24061 gactgctatt cactagagaa caacagctga acaaaatcat gcaaaaaaat caaaaaaaat
    24121 tgaatgacct ctcgctagac aagaaacaag aatttggacg ttatgttgtg atccagcgca
    24181 gaattatgct ttgtcagcag gaactccaat ggtgtcagca agtaagagaa caaatgcagc
    24241 agttttttga gtaagggata aacagaacct ttctagaaat atctattgaa gagcaaatta
    24301 tcttcaataa aagagcaata cagttggaaa agaaaaagcg atccgaacga caggccaaaa
    24361 cctatcgttc ggatcactat ttttctagaa ctgcattcaa gagactatga caaaaagcat
    24421 gccaaggcct tttttcaaat aacagtgttc catcattcat tactttgaat tgcttttagc
    24481 acacttcttg aaagcgggcc aacgatgatc aactgcaacg gtaaagcggc aatcacattc
    24541 attttccaag cattcatata agcagagaat aattgatcag gtattccttg ttccatgatc
    24601 acaccgaata aagacataca tgtcaccatt cctaaaacca tcaagcatga aatagttaag
    24661 atcatttgga ccttgctttc tggatttact ggtagtttaa aggcaatttt tttcgccagc
    24721 acaccgatga tgaagacatc caaaatgaaa gccaccacga atccaggcac tagaccaatc
    24781 aacaaacttg ataaatgaag atcttgatgc agccataaat tatacgcgct catccccaag
    24841 accatcaaaa aacacatcat tgttgtaaaa attattcctt cttttttatt tgtaggcaat
    24901 ctgtaccact cctttaaatt tgtcacgaaa atcatcgtag cacatttaaa aatttctcgt
    24961 aagtactttt tttattttct gcccttttat ttcataaact tcatcagccg tacgctcgac
    25021 aaagtaagaa tcatgagaag taaacaaaat cgttcccgga tatatttgca ttagcttctc
    25081 taaagcttcg atcgttgcca tatcaataaa attagtcggt tcatctaaca gcaacacatt
    25141 acttggctta gtaaaaagca aagcaatcgt cagacgggtc gcttctcccc cacttaatgt
    25201 acataacggt ttcgtcaaag tttcctgagc aaaccctaag tgattcagca aactacggac
    25261 aagcgattct gaaaactctg tttgtctcat gacaaaacga atgatggatt cttcagatgt
    25321 catttgataa cccttttgct gatatacttg aaagcttact ttcggagaga gaaggattcc
    25381 ttctccttgt ttgcggatat gttctaataa ggttgtctta cctgaaccat tttcaccgac
    25441 aatcgcgatt tttttaccta aagaaaactg aaaatcacca tttaccagta atgttctccc
    25501 acttctttcc aattggacat tttgtcccat gatgggatag cggctgtgga gttcaagaga
    25561 ttttggtact ggaaaacgga tttgtttcat ctgctgcggc ttggttgttt ctcctatttt
    25621 ttggagtctt ctctctaatg ttttcgcatt cttttggatg gctttttgta cactgtcttt
    25681 ttgtttagag gaagacaacc gatccggtct gatttgttgc tttttctttt tactggacac
    25741 tttttccaac ttttccgctt gttttttctt ttcttggatc gatttttcca atcgtttttt
    25801 ctctttcatg atcgactctg cttctcgtag ctgagtcttt ttctccaatt ccttttgagt
    25861 gagataggca ctataattcc ccgaaaactc tcggatttct ccgtctttta cttcccagat
    25921 tttcgatgct agctcatcta gaaaatagcg atcatgacta acaaaaacca gcgtaccata
    25981 ataataacga agctcttcaa tcagtcgatc aatacttttt ctatctagat gggttgttgg
    26041 ctcgtctaga agcatccctt gttcataaga agaaagaaga cgtatcaact cgatctttcg
    26101 ttcttcccct ccgctccatt tccgctctga agtttcttcc agtcttaact ggaaatgact
    26161 ggctaattcc aaatttaggt cctttgcttc agcgagatag gttaattgag gcaggtagtt
    26221 gaaggtgatc tctgtttgga ttttcccatg atcgggaaaa agttcaccgg ctattagttt
    26281 gagcaaagtc gatttaccga caccattttc tcctatgatc cctatacgat cttgctgata
    26341 gacacgaaga gaatcaatag atagttctag ctggttgcca aagctgactt gtagatttgt
    26401 tatatttact gctaaatttt ccatatgttt tacactccta tttcatgtaa aacaacaatt
    26461 atcgatacta aaaaagagca gaaaaatctg tttgcaaaaa aactgcatca catcttttcc
    26521 tactctgaac gaaataacta tgactaaatc accaaatctg tcatagcttt cacctattct
    26581 actgtcgttc gaaaaaatgg acatactcca tccatgaaat tgttgtttat acatgtcttt
    26641 tgaatttatt tagttgttat tcaaaagttc gaaacgtaat ttcatcgatg cagtcatttt
    26701 tccgacctcc ttttttatta ggttaccaca cacgattcaa aaaaagcaat agctactgaa
    26761 tagtaactga aaacctttta ttcgaacgta gtgatctttt ctggtgctaa acgaacagac
    26821 tcgtaacctt cttctaccgc ttttcctatt gataaaataa taactggaac ataacggtct
    26881 ttatccaaac caaatgcctc tgccaactga tctgcttcga atccaccaat tggatttgtt
    26941 tcatagccat gatcacgcgc aactaacatg aattgcatag ccgctaagct agaatcgact
    27001 ttgactacat cgttcatttc ttctcttgaa aaactcttgt aataaggaat gatcgcagct
    27061 aattgttgat ctctgacttc ttttggcatc ttccctgatt cgtaagcttg gttatagatt
    27121 tcttcgccat attcgtaaca ttgcatatcg ccaaaaatca tgaccattgc agaagaagta
    27181 tcattttgtc tcgtattgaa acggatcaaa ggacgcaaga tttcttttgc ttcctcgctt
    27241 tcagcgacca caaagcgcca tggttgcata ttgacagaag aaggtgcagt cgtcgcttct
    27301 ttgatcattt ccagcatttc ttcgtgtggg attttgtatg tttcatcata tacgcgaacg
    27361 gatcttctac cagtcataat tgttgaaaaa tcattttttt gttccattat tattaacctc
    27421 tttcgtttct gttgttatat tgcaaagttg ggtattcaat ttatctaaaa gtgttagaaa
    27481 ttgtttcatt tctacatcgc tgaaagccgg ggatagcacg gaacctgtat ctttatggtc
    27541 catttcacaa tgctcgattt tcttctgggc tttttctgtt agcgctacat acacttcccg
    27601 gttgttctga ggatttctct gacgcgaaac atagccattt gcttccaata ccttcagatg
    27661 acgagtaact gctccttgat caatctgcaa cttttcttgc aaactgcttt gtagcaatgg
    27721 attttcttct ttcagtctca tcatgatctc gtatctagta agacttatac cgatattttc
    27781 ttcaaagatc tggacgattt tttgatcggc taatttgatt tgatataaaa ggtgactaat
    27841 ctcttctaaa gacataattt cctcctttct aataattgac tcgtcaacga ttgacttgtc
    27901 aataatagaa taaaaaaaga aaaaagtcaa agaatcagct gtgtaataaa aaaaacgctc
    27961 tcaatagaaa agtatagaga aaagaaattt tttgtagaat gaacggaaaa aatgataaag
    28021 aaagcacaac gctaaaacca agattattga ttcttatcaa actatagaag atagctcttc
    28081 tgcagtagaa aattttacac cgccaaaaat ttccgaaatc gccttttgca agaatcccgt
    28141 cgaatattag aaattggatc agtatgctta aacagtaata aaaaagttat gacaagatgt
    28201 tgtcacaacc ttttttgagt aaacggtgtt caaaaacttg catctgcggt aataagttca
    28261 accaaacaaa aaacatgaaa atctgttttt gtttggctgt tcttactact tgatgcaggg
    28321 cagctttttc actacctctt tttaataacc ataaaatcct attccttcat atctccagcc
    28381 catcggtgtt agccaatctc tttccttagc actcaaggta tagtgatggg taccagtttt
    28441 ttcatttgga ttaaatagtc gataaattgg cttggaacca ccagaataaa aacttagacc
    28501 ttcataacgc caaccgattt ttgttaaaga gttgatctca gattgtgcca ttgtgtaatg
    28561 atggtctcca ctgtaaggat tgtataaacg gtagacaggt tgtccgctgt ttggtgcttg
    28621 ccaagcaatc ccttcatatt cccagcctac agttggcaga taattttttt ctccggcatt
    28681 caatgtatat aaatgttctc ctgtatgacg gttatacaga cgatacatcg gagaagttga
    28741 agttggtgct gtatcatact gtgtcagatt ataggtttcg attacattgt tcaatgtaga
    28801 accataatta ggcgcagtgg cataacgacc tgttagccaa gccgtagcat ctttgtaaga
    28861 gttcgtattg cttttccatg caccggaata gtagtaaacg cctggctgaa aagaagtcgt
    28921 tttcaatacc gttacgttat cttgcaatga ttctttgtac gaaggatatt ttctaaaagc
    28981 ggcattcacc gtaatccatt gcccattcac atattccgaa gtaggcatcg taacagattg
    29041 gccattatag cttcctttaa tcccaaatag attgtaatta ggggcagaag ccaaagtact
    29101 gttcccccag ccactttcaa cgatggcttg agcaatcatg actgatgcat ataagtcatt
    29161 ggcacttgcc aaactttgtg cagttgaggc aatactatca atgaacgctt gttgagaatt
    29221 agcagatgag cgagcataaa aagcatagcc agtatagttt tcgaattcag acaaatctgc
    29281 ttgatgggta tgtgtcaatg tttgcccatc tgtcaattgg ttcgtgattt cttctgcatt
    29341 ctctggattg ttctgagctt ctgctgatgt actgtcttcg gtttgtgttt gttctgttgt
    29401 ttcagttgtt ggttcttcgg ttgaaattgt attttctgag acagtagctg actgcaaagt
    29461 actctctgta tcgttttcaa ttcctgtttc tgaagaactc gatgtctgag ttgcgacagt
    29521 ttctgtcgat tcttcagcta gcactgttgt gttggcaact gctagatttc ctaaaagaat
    29581 aacgctaaat aataaattct ttgctttcat cttttttctc ctttgaatta tgaaactttt
    29641 cctaaataac agtgtaacta aaaaagtaaa agcaagtcaa tgtccatatt taaataacat
    29701 ttgtttcttt ttgataaatt tgctttttct acataaaaag acgtaaatga agaatattct
    29761 tctccattca cgccttaaat tgatggtcgt ttgaataact atttaacaag taattctctt
    29821 tggatattat ccgttatgga ttatacttcc tgtgtcgtcg gacggataat catgttactg
    29881 acagacatcc ggtctggcgt ttctatcgca aatgctacag cagaagctat atcttcggag
    29941 gtcaatcccc attctttttg cgcttcatga agttcaagag cagccttttt gtcgctgatg
    30001 gtttgatata attcagtttg aacagctcct ggagagatga tcgtagattt gatgttattt
    30061 tgccgttgct cttgacgtaa tccttccatg attgcacgga cagcaaattt tgttccgcaa
    30121 taaacggcgg aatcaggata aacaacatgt cccgccacag aatcagttga aatgatatgc
    30181 ccagattttt gtttttccat gattggaagt acggcggaaa ttccatttaa cacacccatg
    30241 atgttgatat caagcatatt ttgccattca tcacggtgac cttcaactaa tggagcggtt
    30301 ggcatgattc ctgcattatt gtacaataca tcgattcgac cgaacttttc catcgctaaa
    30361 tcgataactg cttggacttg tgcaaaatct cttacatctg ctgtttgaat atatagctca
    30421 gcttctggta aagattcttt tattgctttt aggcgatctt ctcggcgtgc agctataact
    30481 agtttagccc ctttttctgc taatagcttc gttgttgctt caccgattcc gcttgaagcg
    30541 cccatgatga caatcacttt ttctgataaa tcattcattc tattctcctc ctgttttgaa
    30601 aaatctcttg cttatactca ctatctctta tttcatctta ctgttcaaat aatccgttcg
    30661 acaggtttga cgattttggc agggattcct gcaacgatgg tattgtctgg gacatctttc
    30721 gtaacagttg cattcgctgc aacaatggca ttctcgccaa tcgttacgcc tggcagaata
    30781 gttgctcctg ctccgatcca agcatttttc ttgatgtgga ttggctttac tgacaagcct
    30841 cttcgttctt ttggatcggt tagatggttc accgtgatga ggttgacacg aggaccaatc
    30901 aatactgaat cttctaaaca gatgccacct aagtcaacga acatcacttg acgattgata
    30961 aagacatttt tccctatact aatatgtttg ccgaaatctg tataaaaagg cagcagaaca
    31021 gtcaccgtat catctacttt gtcactaatg atattttcta gccgtttgcg gatatctgct
    31081 ggttcatggt acccagtatt cagcgctgct aaaggctctt cgttttcagc ttggatctga
    31141 tggatcactt caaagagcgg atccgttact cgaatctctt tattgacgat ttgtttttcg
    31201 atgaggcttg tcattttgct ccctcctttt atccttactt tataacggac ggcttatcat
    31261 gtctaatact tataaaacat acttaactat tccttttaac tatacttagt ggtatgcttt
    31321 tttaaaaaca ggagggaaaa aatggatatt cgtatactga cgtatttttt agcagtagct
    31381 agagaaaaaa atatcagccg agcagcaaaa tctctgcata tcacgcaacc tactctctca
    31441 aaacaactga aagatttaga agaagaactt ggtgtgacac ttttcactcg gggctcccga
    31501 gagatacagt tgacggattc tggtcgatat ctttattcaa aaggaaaaga aatcttgtcg
    31561 ttggtagaaa aaacggcgaa caatttaaca aatgacgcaa tcatctctgg agaaatctac
    31621 attggcggag gcgaaactaa agcaatctct ttcatttctg atagccttca ttcgttgatc
    31681 aaggcgcatc ctgatatcca gtttcattta tatagcggga atgcagatga tatcatagac
    31741 aaactggata gcggattact tgattttgga ctcgtaatcg aaccgacaaa caaacaaaaa
    31801 taccagtcat ttcgactgcc agcccaagat cgttggggac ttttgataca tcgaaatcat
    31861 cctttagcaa agcaaaccgt catccatccg caggaactga aaactgttcc tttgatcatt
    31921 tcccggcaaa cgtcagtgga cagtcaacta gctgaatggc taggtttcag catagatcag
    31981 ttatcgatcg tcggaacata taacttattg tacaatgctt ctttgatggt cgataacggg
    32041 acttttggtg cattagctct agatgggatc atcaatactt atgggacgga aaaaatattc
    32101 atcccactcg atccgccatt acaagcttca ctgaatctca tttggaaaaa agaccagcct
    32161 ctttctcctg ctgctcgtaa atttttagat gtcctaacgg agaaatacag ttaagtagag
    32221 tttttttcct tcgctttcag ctttttaaca acgaataaga taagcaaaag atccaacgat
    32281 taaataacat aagtttctta atttatttct tccttttatt tctgataatt ccagtaaatt
    32341 actataatta taaaaaaaga attgacaaaa cataactgtc tatataaaat tgattacgtt
    32401 aacaataatt cgtttcatgt gactagatca tactaggcat gaaaaatctc tgaggaacat
    32461 ggtttcccta ggaggttttt cgtgtctatt tttgtttggc cgcaatcaac tggtctagca
    32521 aacgtgaaaa ccaaatcttc aaaaagggtg cgcgcatgaa aatcaaaaag atctttaatc
    32581 aaaatgcagt attggtagat gacggtggac aggaaaaagt agctattgga aaagggattg
    32641 gatttgacag aaaaagaaat gatttgattt ttgatcgtga tgtcgaacgg atatttgtca
    32701 tggaaccaga aggtcaaatc aagttgcaaa atttacttaa tcagattgat gaacgctttt
    32761 tatttgcagc agaaacgatc attgatcatg cggaaactgt tttgatggaa aagttgaatg
    32821 aacatgtatt gatcgctttg accgaccaca ttgctttttc tgcggagaac attaataacg
    32881 gtatcgtcat ccgcaacaaa cttttaagag aaatcgaagt gctttacagt gatgaattca
    32941 gtattgctca atgggcagta gagtatctga caaaagagct tgggattcca tatacttatg
    33001 acgaagcagg atatatcgca atccatattc acagcggacg aagcggtcgg aacaataacc
    33061 atcgcagtat ccgtgaagtg acgattgtat ctgacatcat ccatttagtg gaatcagaat
    33121 tggaaacaga tatccattca gaaccatttt cactgaatta ttcaagactg gtgaatcatt
    33181 tacgactgct tctacaacga acccatgcgc aacaatatgc tgttttagac acggaaatcg
    33241 tagaaatggt caaacgaaaa tacccagaaa gctataagat ttctaaaaaa atccgtgtgt
    33301 tgctgaccaa agaataccag ctcgcgatca cgaaagaaga actgggttac ttggccatcc
    33361 atatcgagcg tttaagaagc gcaatcgtac aaacaaatgt taacaatcat gaggaggaaa
    33421 aaaattgaaa gcatatctac aacgaatggg acgttccctt caacttccag ttgcggtctt
    33481 acctgctgct gctttactag tagggatcgg aaactggtgg gcatcttata gtaacgacat
    33541 tgtcgctcat tttttacaag ctggcggtaa cgcagtttta ggtcaattac ctttgctgtt
    33601 tgccgttggg ttagcactag ggatgtcagt ggacaaatca ggtgctgctg ccttggcagg
    33661 tttggtcgca tttgaagttc cagtaaatgt tttaaaaact gattcagtag ctactttatt
    33721 gaatatcaaa ccagaatcag ttgatccatc ttttgctcag atcagtaacg tatttattgg
    33781 tattattgcc ggattgattg cggcagctct ttataatcgt ttccacgaag caaaattacc
    33841 gatggcttta tctttcttta gcggcaagcg tctagtgcca atcttggctg cctttgtcat
    33901 gttgctgatc agtgcagtgc tactgctcgt atggcctccg gtttactctg ctttagtttc
    33961 ttttgctaaa ttcattttga gtttaggctg gggtggtgca ggtctttatg gcttcttcaa
    34021 ccgtttactg atccctacag gattgcatca agcaatgaac tccgtgttct ggtttgacgt
    34081 agcaggaatc aatgatattg gtaaattttt ggcttctgaa ggaacaaaag gcgtaacagg
    34141 aatgtatcaa gctggatttt tcccaatcat gatgttcggg cttccagcag gagcatatgc
    34201 tatttacaga aatgcacgtc cagaaaacaa agcaaaaaca gcttccttga tgctagcagc
    34261 agcttttgct tcattcttta ctggtgtgac agaaccactt gaattttcat ttatgttcgt
    34321 tgcttggcca ttatatgtct tgcatgcaat tttcactggg atttctttag cagtgagtgc
    34381 attcttccat tggacagcag gatttgcctt tagtgccgga tttgtcgatt acttcctatc
    34441 tttgaaaaat ccgattgcga atcagccatt gatgttgatc gtccaaggat tagtaacagc
    34501 agtgatttac tactttggct ttaactttgc tatcaaaaaa ttccatctga tgactcctgg
    34561 ccgcgaggaa gcagatcttt cagatgacga tactgcaacg actaattcag acaataaata
    34621 tgcggcacaa gcaagcaaaa tctacgctgc attaggcgga gccgacaatg taacttcgat
    34681 cgataactgt actacacgcc ttcgtttgca agtcaaagat acaggcctga tcgatcaaaa
    34741 taaaatcaaa gccactggcg tacctggtat gaagatcatc gacggaaaaa atgcgcaagt
    34801 catcgtaggt acagaagtac aattcgttgc agatgagatg gcaaaactac atggtggtgc
    34861 tgcagcacga cctgcacaaa caaacaccgt ggttaaaaca gaaacatttg ccggtgaaac
    34921 gatcgaacaa gatatttacg ctatcgcaaa tgggaaactg attccaatca ctgaagtttc
    34981 agatgatgta ttcgcggaaa aaatgatggg tgacggctat gctgtattac cagaaaatgg
    35041 agaaatcttc tctccaatcg ctggtacgat cacaaacatt ttcccaacga aacatgctgt
    35101 cggaatccaa acagatgctg gtatcgaagt cttgcttcat atgggcatca acactgttga
    35161 cttaaaaggc gaaccattca ctttatatgt agaagaaggt caaaaagtcg caagaggtca
    35221 attgattgct ttagttgatc ttgccgctat tcaatctgca ggcaaaaaca cggatatggt
    35281 cgttgtattc acaaatggcg acaaagtcca aagcttagaa atcgaacccg cacgtgatgt
    35341 aaaagcaaat gataaaatcg gctctgtttc caacaaagcc tgagccatcg tcttccccag
    35401 acttttttat cgataaacaa acaggagctg agacaaaaat cttgtctcag ctcctttttc
    35461 cgaataaaaa cggcgttctc ctgccaactc cgcggtaata agtccagcta aacgaaacat
    35521 atgaagagct attttttatt tgactcttct tattacttga tgcagaacag ctttttcaca
    35581 aaatttttct tcatactcaa aactaatcgg ctttttcaca acctctttat acattattcc
    35641 tgatccaata tttcttttaa tgctgcttca agagaagtta atggttttcc caatactttt
    35701 tctaaatcat cagaggaaat agctaactga tcctttttaa tatcatgttg gatcgctaaa
    35761 aacatgtcag ctgcttcttg agggaatccg gcttctttta gattttcgac aaacgctgca
    35821 tcacttgctt caataatttc taactcttta cctgtcgcac gctctaatgc cttggctaat
    35881 tcttcatagt cagttagatt gccggataat tctaagattt ctggagagtc actttctact
    35941 agtacttttg ctgcagcttc tgcatattca cgtttcaatg cccaacctgt ttttccattt
    36001 cctgcagcat aaacgaattg accagttttt aaagcctgcc caatgatagg taattcattc
    36061 tctacatacc aattattccg taaaaatgta tgggaaatac ctgaatcctt aatcattttt
    36121 tcagtgaatt ggtgatctgg cgctaataca ctgatcgagt gatcggcatc tgcaaaactt
    36181 gtataagcga tataagatac cccagctgct tgtgctgcct tcactacatt cttatgttcg
    36241 gcttgacgat ttcctggaac gccagagaca aaaagcaatc gatctattcc tttcaacgct
    36301 tctttcattg agtctaaatc atcataatca ccaatacgta tattaaatcc agcttctttc
    36361 agtgcttctc ctttttcttc actacgtact agtacataga tttcattttg tggaaccatc
    36421 ttttttaaga attccagcgc ataaccacca aaacctccag ttgctcctgt tactaaataa
    36481 tgcatatttg ccactcccta ttctttttat ttgttaagat ttacagctgt acatttataa
    36541 attacacctt tatcataaag agtgtggtaa gataagtcaa gcaaaaaaaa tgaaaggatg
    36601 acaactgatg aagtattctc tgcaatttag tgatgcaatc catgtacttg cctatattga
    36661 aatgtttcaa gatacccgat cactttctag tgagatgatt gccagtagta tcgaaacaaa
    36721 tgcagcaaat gtacgtaaaa tcatgagtca gctcaaaaaa tccggtttga tctttacaaa
    36781 aaccggaaaa ccgcagcctt cccttgccaa aagtccagat cagatttctt tactagatgt
    36841 ctatcgcagc atcgaaggta atacacagct tatccaagtc gatccaaaaa caaatccaaa
    36901 ttgcgtcgtt ggtgcgaata tccaagaagc tttagaagaa agctacgctc ggctgcagaa
    36961 aaaggcagaa gaagaaatgg ctaagatcac acttgatagt ctgatacata aaatagccgt
    37021 tttggaaaaa gaaaaaagac cagaaaacac aggcctcgta gagagatttt tataattctc
    37081 tctactgtgc ctgcattttt ctgatcggaa tcgtctacat aaattctttt attctccggg
    37141 ggacaaaagc cttgtcatgc ccctttttcc tctctaatgc tcaggtcaaa gcgctgaagt
    37201 catgacgtct tgataaacgg tgttcaagta gctgaccctc ggcattagtt ctgaaaaatg
    37261 caaaatatgg aaagctattt cccatttttc ctctctaatg ctcaggtcaa agcgctactt
    37321 tcacgacctc tatattatca tggtttattg actaccggta tccagatttc tcccatatat
    37381 ttcccgttgg taactcccat ttcgactaca gcatttggac ccccaacata ggcgtaatct
    37441 tctacttctc ttaaaacatg cccaaaggcc gtattcgtca aatcatttct taattcttca
    37501 ggcgattctg ctaaagcgct tacaacaaga tacgttcctt ttgggaatgg gatgattcgc
    37561 gtagtgtttg gaacatcctg actcgtttga acaccgacat agtacatcat tttcccgtta
    37621 tagggttcgt tgactgtaaa gaaataatga ttttcagcag cttgtttcaa tgcatctatt
    37681 gttccattac cgataacttt ttgctcaaat gcttgtttct ctgcagccaa accgacaaaa
    37741 tccgtattgc tactcttcaa ttccacacca atacccgtca ccgtaaaatc tggtttttct
    37801 tcgatcctat actttgccat ttctcccacc ctttctatta tattaagttc atcttacata
    37861 aaattaaagg gaaatgacac gattacgctc ttttttctag ggatattttt attttttaac
    37921 tatttttttg ctttcactgc aatccaaatc tcactgtaaa cattactgaa atcctctccc
    37981 cattttgtaa aagagatctc gggagcttcg actaacccat aatctgaaga aggaagccat
    38041 tctgcataga ttttccccca agtatcttgt aaagtttggg gaaatggccc tttattagga
    38101 aaaatggccc aagtgtgttc ttctatagca agcatttcta aatcagcgta cggattttct
    38161 tttgtcgtag caaagccaat catgtgcatc aaactgccct tttcttccaa gcggtctcca
    38221 tcaaatccat aagaaacgtt gattacttga tttggatata aatctcctaa cttatgcatc
    38281 tcttcccttt gagtctccgt gatcgtctgc gctaactttt gtatttcttg attgactcct
    38341 tcaaatttga caggaacttt tttcgccaca cctgccacat aaaactgttc tttcttttcg
    38401 atacgaaatt ccatcgattt tcctcctctg acatcaataa aaaatgtcaa gcgtggaaaa
    38461 gatttttgta tgccgtatct actgatttct gaaggcagat atcctgacca atcacgaaaa
    38521 gctcttgaaa aaccttcgac tgtttcatat ccatatctaa acgccgtttc tgtcactctt
    38581 gatccatcta gaagatcgcg attagccaaa gccaatctac ggtttttgat atagtccatt
    38641 agcgacatcc ctgcaataaa cgtaaagatg cgttttaatt gatattcaga gattcctgta
    38701 ttttcggcta ttattttata ggaaagtcct tctgtcaaat gttcttcgat gtaatcgatc
    38761 aattggttca gatctttaag catatttatc ttcctccttg attgcctttt tatcatatta
    38821 tcaaagaaag tcaattactt gatgaatcag gaaccaattt agtcagatgt agaaaatgtt
    38881 gtatggatct aaagaaaatt ctcaagcagc gtttcgtaac ggataattgg tattatctgc
    38941 ctatctatgt tttaccttta gaaaaataaa ttttggggaa gacagattct aagtaaacaa
    39001 agcggtaaaa atatctttta ttcccttagt taatccgctt actacctact gtacaaagca
    39061 aattgttgtt caaactgctg atcagaacgc tgcttggatt tttctttgcg atacatcata
    39121 cctcttttat caattggaac aattatttat ttctaacaaa atcacttcat ttttgtcaga
    39181 taaataaaaa acaaaaaaag ttccatcttt aaaacacgct attcttttac tttttctcac
    39241 attctctaag aaaagaaaag gagaatgaat ttttgacaat tcgagcaaaa gtgattatca
    39301 aatatgtaaa atcagctact tttttcttaa acgtttcttt atactaaata taaataagtg
    39361 tttcatgaaa ggagaactag atgaataatt ggcttgagta ttttcctgaa aacgttttgg
    39421 aacgcggtta cagctatcat ctgcacggtt ttgtccgtca tttgaactat acaagcaagt
    39481 acttgtccgc aacagtttct ggcacggaag attataaggt agtgatcact tgggatgaaa
    39541 agaccaacat gacttgtgat tgtctatatg ccatagaagg aaaaaaatgc aaacacatgg
    39601 ctgctgtctt attcgcttac gaagaacgtc caataaaaaa atccaactac tcactttccg
    39661 aactctcgtc ccttgtttcc tccgctagtt cctctcttgt acgggagctt ttaacagaga
    39721 ttcttataga acatccgcac tttatcgaac gcttcaaagt taagatgcca tttcatgcaa
    39781 taaattattc agataaatta acaactatca tccataaata cgatcatatt atcaagaaaa
    39841 acaaaaacag gaaaacagcg aagttcatca tggagatgcg aaagttcatc caagaagcag
    39901 ttgaatcgct tattcagcaa aatgcctatc ttcccgcatt cgaattgatc aatgaagtga
    39961 ttgctactct cgaaacattc tattgggagc ctgaggatga acgaaccctt cttctgatag
    40021 aggactgtta ttatttatgg aaagaattat tagcagaagc acctcatgca gaaaaaaggc
    40081 aaatgttctc ttggttcgtc tgccaagtcg atcatactga cgcctcttat tcaaaacgct
    40141 actctataaa aatcctgaaa gaagactttc gggaaaaaga attttctaac caaaagaaaa
    40201 aaatagataa aaaactaaag aaacggtaaa gaaagacgat ttcaatgaaa aatagcaagt
    40261 aaacgataac aaccatccta aatccacaag aaatacagca gaccttgctt taaaaacacg
    40321 aatcatgcaa aggatgaagt aaagaagact taacgcgtac ccaatattag tcatttgact
    40381 attaggtacg cgttttgttt tataagtcat gacaaatttc cttcgttgct ggatagattt
    40441 tccggcattg ttgatagatt ttatgatact tttctacatt ttgtaagaga ggttccgctg
    40501 catctgtata ttggataaaa ttctgacaac aactttcagg tgtgtcgaac caccctaacc
    40561 ctagtgcagc aatcattgtt gcgcctaatg caggtccttc ctccatactt aaacaataga
    40621 ccgttgcatc gaaaatatca gcttggattt gtagccatgc aagatttttc gcgcctcctc
    40681 ccaccgaaac aatacgtgta aatctgcgac ccgctagttc tttacgtttc aatcccacca
    40741 ttgacaaatg ctcattaaaa atttagaata ttcacaagtt taacgacaat tatgaaaatt
    40801 tatgtcgtgc taaaggagtt ttgttattgg atgaaaagtt agatataaaa actgcgatca
    40861 aagacacgtt acctaccgtt ttcggttata tcggtattgg acttgcattt ggtatcgttg
    40921 ggaaagctgc cggatttcat ccactagtcg tcacgttgat gtccctgctg gtctatgctg
    40981 gttctgccca atttatcaca gtcagcatgc ttgctagtca cagcccattg ctttccatcg
    41041 ttttctcgac ctttctagtc aattcccgaa tgattctgat gagtatgacg attgctcctt
    41101 atttcaagaa aaatcggctg cttcaaaatc tgctgattgg cacattgctg acagatgaaa
    41161 gtttcgcact gggaatgaat aaattgaact atactggaca aaagttaaac tttcgttgga
    41221 tgaatacagc taattggatt tcttatttga cgtgggtggg ttcttctctt gttggcgcac
    41281 ttttagggaa ttttattact gatccgaaaa agtttggttt ggatttcgcc atcgtcgcta
    41341 tgtttatcgg gttactttat cttcaagtca tttctgatag aaacacctct aaacgattac
    41401 agttgatcct gattggtctc actttgattc tggtatatgt cggactgatt tttatcccaa
    41461 gcaacttagt gattgtagtt gtaacactga ttgggtgcgg attgggggtg tggatcaaac
    41521 atgccttctt ttgagtttac attgctgact attttaggtt gtactttagc aacttggctt
    41581 tctagggtcc taccatttgt cttactgaaa aaattcgatt taccgcaacc gttgcttgag
    41641 tatttaagtt ttgtcccgat cgtcattatg tctgctttat ggttcagcag tctatttacc
    41701 caaaatatcg gacatctgcc gcagatcaat ctcgaaaatg ctttggcttc agttcctaca
    41761 cttttagctg ctattctttc aaaaagctta ttggtgatcg tcttggcagg aattctttcc
    41821 ctttcgttga ttcgcttatt ataaataaaa aaacaagagc ttatggcaaa ttactgtcat
    41881 gcgctcttgt ttttatcaaa gtcaaataag aaaaaaatcg gcgtattctt gcttatccgt
    41941 tgaacggacc actaacaacg acttttccta acatatgtcc tgtttctacg tctttggttg
    42001 cttgtttcaa gttcttcgca ttcatcccat ctgaatagac cttgctcaat gtactgcgga
    42061 taatcccttc atttgctaaa gcagcaatgt gcgctaaagc ttctccttgc gtttcgattt
    42121 catagttata gtctgtttta gcgaacatat actcccagtc gaagctgata gattggtttt
    42181 tccaaacacc tatatctaac ggctctttga tccctacgat cgttcccaca tgtccaaatg
    42241 gtcggacaag gtgcttgatt tgatcaaagt agcgggtaat atcgaataat acagcgacat
    42301 actctacttg atcgattcct aattcacgaa aacttttact taagtcgtga tgataatcga
    42361 ttggatagtc tacacctgtt tttttcagcc attcaaaatt cttcggactt gcagtcgcgt
    42421 agacttctag gccagcccaa tgcgctagtt gattcaaaat cgaaccgacg cccccggatc
    42481 cgttgatcac taagattttt ttcccgcgat tggcattttc ttctggagtt agaccaaatt
    42541 tttcaaataa caattcataa gcggtcaatg aggtcaacgg caaggctgca gcttcttcat
    42601 ctgaaagatt ttttggtgca agagcgacaa tacgttcgtc aactagttgg tattcttgat
    42661 tgcttcctgc tcttgttgtt gtacctgcgt aaaaaacgcg atcgccgaca gaaaattttt
    42721 gcacttcgtc acctacagca acaactttcc cgactccatc aaaacctaag atacgtaaag
    42781 catttcttat cccgttatct tggcgaagtt tcgtatcgac aggattaaca gatactgcgt
    42841 tgacttttac cagaagatcc cgtgaactgg gtacaggtat ctgttctttt tcatcaataa
    42901 agctttttgg atcatcgatc ggcaaccctt cataaaaacc gactaccttc attaattcct
    42961 tttctgacat acgaattcct ccttagcttc atcaagttgg agcatccata cagtgttcat
    43021 ttcaatatat atagtatgct atttgttcca ccttttttat tcatcataat tattctctta
    43081 cttaaagtaa actatttgca cttttttggt taaaaaagag gttgcgacaa gacttttgtc
    43141 acaacctctt ataaacggtg ttctcctacc aactcttcgg tcacaagtca aaatattcat
    43201 caaacatgag aagctgtttt ttgaaattgc tccttgtgac tcagagttaa acggcaggct
    43261 cacaacctct gatataaacg gtgttcaatc aactgaccct cggtattagc tcaaaaaacg
    43321 acaaaatatg aagagctatt tttgtttggc tgttcttatt acttgataca ggacagcttt
    43381 ttcacgacct ctaattcacg gtgttcaagc aagaaatcat tgttcactga aaagcgttgg
    43441 atgttctttt tcaaaggtct ctaagatctc tcgtacttca tcagtagatt tcgtattcat
    43501 caactgaact cgcaagtcat ttgctcctgg aaatcctttg atatagattt taaagaaacg
    43561 atgtagtcct gtgatggaac gcgggatgat ttctgaataa tgatcttgca gatctagttg
    43621 cagacgaagt agtccgatca gttctttttc tgtatgttcc ctcgggtctt tttcaaatgc
    43681 ataaggattc ttgaaaatcc ctcggccaat catgatgcca tcaacgccat atttctcggc
    43741 caattcttct cctgtctggc gatcggggat atctccattg atcgtgatta gtgtttgtgg
    43801 agcgatttgg tcacgtaaag caatgatttt aggaatgact tcccaatgtg catctacttt
    43861 actcatctct ttacgcgtac gcaaatggac agaaagattg gctatatctt gatgaagtag
    43921 gtgactgatc cattcttcca tctcagacat ttccgtatag ccgatacgcg tcttgacgct
    43981 gacaggcaaa ccgccagctt tagctgcttc aatcaattgt gccgctactt ctggacgaag
    44041 gatcaagcca ctgccttttc cacgttctgc tacattaggg actgggcagc ccatgttgat
    44101 atcgattcct tggaagccca tttctgccat agcaatgctc atttctctaa aaaattctgg
    44161 cttgtctccc caaatatggg caaccatcgg ctgttcatct tctgtaaatg ttaatcttcc
    44221 tcgtacactg tcttttccat ctggatgaca gaaactgtct gagtttgtaa actcagtaaa
    44281 gaagacatcc ggtgctgctg catgctttac gacatggcga aatacaacat ctgttacatc
    44341 ttccattggt gctaaaacaa aaaaaggctt tggcagctct ttccaaaaat tagtagtcat
    44401 ttatttgtta ctctccattc tatcaagcag tgaagtcgca atctttctca aaaacattgt
    44461 cattatacta ggaaacaaaa aaagaagcaa agtgaacagc ttaaaagatg tttctgattg
    44521 agcaaaaaaa agactgtgac aaaaatctta tcacagtcca ttttccggaa taaatggtgt
    44581 tcaaaagctt gcatttgcgg taataagtcc aaccaaacga aaaataggag gagctatttt
    44641 tgtttggctg ttcttattac ttgatgcaga acagcttttt cacaacctct ccactaaacg
    44701 gtgttcaatc agctgaccct cggtattcgc tcaaaaaaca acaaaatatg aggaactatt
    44761 ttcccgtttg tttctctaat actcaggtca aaacgctgat ttcacaacct cttttctaac
    44821 ttctcaatcc tcttccttta ttgatcaaat accaagtaac ggcgtacaaa acaacgatga
    44881 ataacacaag tacgatcatc gatgttgcta ctggcacatc gatcgttcca aggaatccgt
    44941 aacggaaacc ggagatcata taaacgatcg gattgacttt tgaaacagct tgccaaaagg
    45001 gcggtaacat agagatggca tagaaaacgc cacctagata agttaacggc tgcaagacaa
    45061 atgtaggcac gatcgataca tcatcataag actgagcaaa aatcccgttg agcagtcctg
    45121 ctaatgaaaa caagattgcc gtcatcaata atgtaatgat gaccatgaac catgaataca
    45181 catgaagtgg tacaaagaac aaggaaatga tcgttacgag agagccgacg agaatactgc
    45241 gacccacacc accaatcaca aagccccaaa taatcacatg cgtaggaaca ggtgctacca
    45301 agatttcttc gatatttttc tgaaattttt gagagaagaa ggacgaagaa acattggcat
    45361 acgaactagt gatagcagac atcataatca aaccaggaac gatgaattcc atatatgaaa
    45421 aaccacccat gtcaccgatc cgcccaccga tcatttttcc gaaaataaca aaatacaagg
    45481 atgtcgtgat cactggcgga accagtgttt ggacccatat acgcaaatag cggttcgttt
    45541 ccttgatagc taaacttttt aatgcagtaa aataaagatt aaacattttt ctcctccgta
    45601 tgattatttt cttctgtgat tttcaagaac agttcttcta aacgattcga cttattcctc
    45661 atagaaagaa ctttgattcc ttgtcttgta agctgatcga agattccgtt caccccttga
    45721 tttcgttcaa cttcgacagc gattgtctgc tcatcttcaa atgtacaagc atatccttca
    45781 atcacaggtt tggtatcata tggcgctaaa tcaaagataa atgtttcaaa ttgcagtttt
    45841 gacagaagct ctttcatact tgtattctcg atcagttcac ccgattggat gattccgatg
    45901 ttgcgacaaa gcatttcagc ttcttctaga taatgcgtcg tcaaaatgat cgttgtacca
    45961 ttttcgttca attctcgtag aaactcccac atctcgcgtc tcaactcgat gtcaactcct
    46021 gctgttggtt catccaagat cagcaaacgt ggttcatgca tcaatgccct agcaatcatc
    46081 agtcttcgct tcattccccc ggaaagcata cgtgcacgga catttctctt ttcccaaaga
    46141 ttggactgct tcaaatattt ttcgctgcgt ttcatcgctt ctttgcgaga gacaccgtag
    46201 tagcctgctt gattcacgac gatttgctgg accgtttcaa aagggttaaa attgaactct
    46261 tgtggaacca atccaatctg ttgctttgct cgaactagat ccttgtccag atcataaccg
    46321 aagacattca cttttccaga tgttttattg actaaagaag taataatccc gatcgttgta
    46381 gacttcccag ctccatttgg ccctaatagc gcatagaaat ctccttcttt caccgaaaga
    46441 tcgattcccc gcaatgcttc gaccccactt ccatagatct ttttcaaatt atttatttca
    46501 agcgcatttg ccatttattt cctatctcct tatagacatg attcttaatt gtatcatgga
    46561 atacagcaga tgaaaaaaca acttggcttc cacacaaaaa cacacctgct aacaaagagg
    46621 agatgtgttt tctagttcat gatcatcttc gatagaataa ctatctaaac aactctggaa
    46681 cttttaaaat cataaaagta ccgacagcaa ctactacgat gacatataga agatccttat
    46741 aactgaggtt cttgtctttt ttattcatgt taagctttcc tccgtccttt tatcgaaagc
    46801 ttttttcttt tattttaacc gaaataaata aaatggaaat agttattttc aatttctgtt
    46861 ttcgctgttt gttttacgga gaactttgcc atggaacgtg cgtctcgtcg ctgatgctaa
    46921 gttttttcga taaaagctgc tagaaggaag acagcgtggt ttattttgta tcgtcttttg
    46981 ctaaatcttc caagatcatc tggacagcag actcgttccc attgaattct gccacttttt
    47041 tggcatcaat gtacttcttt tgataatcgt ctttttggac ccacgcatca tgcttcgttt
    47101 gataaagtta atcaaacgga taccactgac gctgttcatc gaacaacaaa ctttcttttt
    47161 gggcctgttc aactatggat ttaggataat tcaaaacttt cagcaaggca atcgcatttc
    47221 gggtccttga aggtccttct tttaatttga aatcaaaact gattcctttt ccttctgtta
    47281 cttgttcttc aaagtggaca ttctcacaat aattctttaa aatctctgtc aattcgatat
    47341 catgtgtggc gacaaatgct aaagatggat actccgcaag ccaccgaacg actgaagcgg
    47401 aagaagcaat ccgttcgatc gtatttgttc cttttaaaat ctcatctacg aagcagtagc
    47461 agcgttcttt ggaagccact tggtccagca aacgtttgat cgatttgatt tctgaaacaa
    47521 aataactgtc gccttcaaat aaatcatctt cgattgccat ggaagtcaac acatgtccag
    47581 gttgcagggt aaactgttct gcaatcgctg tttggatcgt ctgtgctaga atacagctga
    47641 tggctatact tttgacatac gtagattttc ctgatgcatt ggaacccgtg actaatgtat
    47701 tcttctgcca gttgactgga ttaactaccg cttcttttaa caatggatga tagatatctt
    47761 tcgctgtcac accgccctca gtaaactctg gtcggcaagt gatcggcata taggtgcgat
    47821 aattcaaaac ggctgctgca acttccaatt ctcccagcaa ttcccacagc ttgatggctt
    47881 cagttgaatg cttttctaat ttagtgagaa cgaaatgata ggagataaat ggcagcatga
    47941 acatgatgtt gacatattca aaaatcaatt ctgcttcact cccgctcttc attcgaaatg
    48001 aaaaacctaa tttagggatg tctcttaatg gtttagtttg ctgtttcagc tctttttgaa
    48061 gtggtgtcgt catttttgct aactgattgg cggctgaaat cgttgaaacc aaataactca
    48121 tgctattcag ctctgtttct agtgtttgtt tcttcactag ataatagacc gtattgaata
    48181 ctaagccacc gattgctaga tagattccta gtacttgccc taaaagaagc aaacctacac
    48241 ccaccagcgg aagcaagcca agaaaaataa ataaacctac gcgtccaatc tttttacttt
    48301 ttccatccgc tagatattgt tttgcaaaat tatgatcttt ttttcctaaa cgagcgaatt
    48361 gatattggat tctttctctc agttgaggat tttcctgata aaaagcaatt agtttttcta
    48421 actgataatc ttctccaaaa tcaaagctac gtaaacgctg atacaacgct tctgaaccta
    48481 cactagaata ggtactgttg atcccttcaa atacttcgaa catatccaag tcataccaag
    48541 taagatcgtc gatttcacta tcccatgaac ggaatttttt ctccgtgagc cacgcatcct
    48601 tcaaactttc ttctttatca aatctcggtt gataaggaat ttttccccaa ttactacgaa
    48661 ctgtttcctt tactttcaaa cgtgaaaaaa tgtctaaaac aactaataaa ataacaactg
    48721 caataataat taaaacgata aattctcttt ggcccatatc cctctccgtt ccttgatttg
    48781 ttagttttag tatagcactg ttgcgctatt tgaaaagggg gtacaaaaat aactgtcttc
    48841 gttacctaat tcgtatcaat cacaccaaaa taaaaacacc ttccaaaaaa gaagatgtct
    48901 ttaaaacgag atacaatttt ttgtcattca cttcaggtaa attagagcca attaaaccct
    48961 ccgcaacttg acggagatgg agaagatgcc cccgtctaat ctagcggtca tctctcctcc
    49021 cattccttcc accaattttt ttgacaggta aagcccgatt ccgctagatt ccgtatttgt
    49081 gcggctggta ttttcggtat aaaaacgctg gaagactttt tcaacagagg tttgcgctcc
    49141 tggtttgata ggattggcca ctgttaatcg aatgaatgaa tcctcttttg aaaatgtcac
    49201 ctttgcttgt ccatctgcat aacgcaataa attctgtatg atattttgca gcactcgcag
    49261 caacatgagc ggatctgcta atacagttgt atttatcgag tgttcagcga acgctacctc
    49321 gatatttttc tcagaaaatt gttcataaaa agagaaaaat acttcttcca cctctttaga
    49381 aaaagaaagc gtatggagat ccatttcttt ttgcttcgtc tctattcgag caagatcata
    49441 aaactgatcc gtcatactga gtaatcttgc aacagattgt ttgatgatcg ttaaatactt
    49501 ctcccgtttc tccgtatcct ctacctgttc cagtaattgt acataaccgt taatagcagt
    49561 caaaggagtt ctgagatcat gagaaaggcc gacgatcgat agtctgatgt tttcttccat
    49621 ttcttgaaat gcttgtcctt tttgttcatt ttcatccacc catgtattca gtgcatctac
    49681 taggtccatt agattctttt ctcgaaattc gactgaaaga cgaccaccat attcttgtcg
    49741 ttcagaaaga gtggcgattt tcttagttaa tctcttgatt tccctttgca ggaagaaaat
    49801 aaaacttccc ataaagataa caacgagaag caacagccac ttaatcaaat ctaaacccca
    49861 ctccccacac cgtatgaata tacacagcat gtgcctttgc tagtttccct cgaagattgg
    49921 aaatatgcat attcactgtt ttctcactat caaaatatgg ttcttgccaa actgtttcat
    49981 aaagatttgc tcgcgaaaat acttttttcg gatgttctaa aaaaagcttc agcagatcga
    50041 attctcttcc tgtcaaatgg acagccacac cattcacatt tacatccctc gactctttgt
    50101 ccagtaagat ttccttgtaa tagatgcgtt gcgacagatc ttttacttgg acagaagtct
    50161 gatgacgaag ttggatgccg attcgtaaca acagttcttc gatatcaaat ggtttcgtca
    50221 catagtcatc cgctcctgct gccaacaagg aaactttatc tctttgatcg ctttttgctg
    50281 aaagaacgat gatcggaaca ttcgatgtct gtcggatttc tgctaacaat gcttcacctg
    50341 aaagccctgg aagcatgaga tctagaagga tcaaatcgac aggatatgtg cttaacaata
    50401 attttccttc cgtacctgaa taagcatcaa gaagtttgta tctctgttca agaacctcct
    50461 ccagtaaaga atgaacagct tcatcgtctt cgataatcaa aatagtttcc agcaggaaca
    50521 cctacttaat gtcagatttt tggaaaataa acattcctag agctgatgat accacgattg
    50581 ttactagact gaccagaatc attttcggtg cttgcgaata agttgcttgt tgcgcaaagt
    50641 ccgtatacat gagccacgtt tccgtaaacc actccgttag aaattccaag cctttgattt
    50701 ttgcgaaaac accgggaacg aaggccgttc ccatgatata aagaaaagaa agaagcaaac
    50761 tgacactggt acttctagtg atgaatgtca aagccactgg aacagataat gtcgctaata
    50821 tcagcagaag caatacagga aatactttta gaacataatt tccatagttt ttgattccct
    50881 caacttcacc aaatccgaaa gcaagtgtgt aagcaatcat ggctagcccc gtaatcaaaa
    50941 ccacgccaag tgttgtgatc aaaagcgtaa cgagaagttt cgacacataa taagtcattc
    51001 gattccgtcc taaagataac gtattgcgaa tcgtaccgtt ttgaaattct tccccaatat
    51061 aaaagcacgc aaatgctgcg aaagccagaa gaatccatgc agccattttt tccaccatta
    51121 aaatccctgt tgcaccgttg atgactgtat ccgttgcttg gtttaattca ttgccgtatt
    51181 ttgtatgcat ataccattcg ttccaagaat aaaaaagcgg aagtacgacc atcagtccta
    51241 gtgagaccca cattttacgg ctcttccata cttttatttt ttcagcagtt aatagattaa
    51301 acatgtggat tgcctccagt taattgtaag aaataatctt ccagtttttg cccaactagg
    51361 tggataccat ccacaggaac ttttgcctct accaatgctt gattgatggc tgctacttgg
    51421 tcaattcctt caaaaagctg gataacacgg ctagattgga caaaataatc cctataacca
    51481 agagagtcga gaaccgttac tgcttgttcc gtcgccgaag tgtcaatttt tataaattga
    51541 cgagattctt gtgccaattc ttctttcgat aattctttga tcaagtgtcc ttcatgcaaa
    51601 ataccgtagt gagtggcgat ctgtgacaat tcatctagca agtggctaga aagcaagacg
    51661 gtgatgcccc gttcttttac caaacgttgg atgatttctc gcatttctgc catccctgct
    51721 ggatccatcc cattcgtcgg ttcatccaaa atcaaaaatt ctggattcgt gatcagtgca
    51781 tttgcaatag ctaaacgctg gcgcatacct aaagagaaat tctttgcttt ctttttccct
    51841 gtattttcca atcgcatcat tttcagcagg tcttcgattt ctctatccga cacaccgccg
    51901 ttcgctgctt ggatacgtag gttatctctt gcagttaatt ctggataaag agcaggggtt
    51961 tcaatcgatt gacccatacg tcgtcttgct gcctgcaaat ccgtcgttcc aaataattcg
    52021 atcgaacctt catcaatcga gatcaaaccc ataatagttc tcataaaggt agacttaccc
    52081 gctccattct ccccaatcaa accatagatc attccacgtt tgatttcgat cgatacttta
    52141 tctaatgctt tggcagcacc gtattttttg gttataccag ttgctttcaa gaccgtttca
    52201 tttccaaaat ccatacttat ccttctttct tattgataag tgaagtatag ttgacgggta
    52261 taaagaaagc agccagaaat gtataaagaa agtgtaaatt ttccaattga atttcaagaa
    52321 aaatcagact gtctcgcaga cgtggttgag ttgtctgcca atcaaagagc gcaccaaaca
    52381 gtgctaatcc aagtggactg gccaccatgg taatcgttgt tatcgttgac atcagacgtc
    52441 cttgtatatg cgttggaact tctcgctgaa gccagaccat ataaaaagca aaagaaaaca
    52501 ttaatcctta aaaacggact tatgaaaaat aatacatgcc gtttgggatt tacaattagc
    52561 taccaaataa gaggttatga caaaagactt ttcacaatcc cttcttccga ataaacggtg
    52621 ttctcctgcc aactcctcgg tcacaagtca caatatttat caaacatgag aagcaatttt
    52681 tgtaaattcc ttcttatttc ttgaagctga ccacttctgt cacaacctca gaagcggata
    52741 aataatattg tttgatgata ctttatcttt ttcccgtttg tttatagatc gaatgatatt
    52801 atagaccaag aatcctacct attaacatag ctaaaaacac aaaaaaggca ctttccaaat
    52861 tgtggaaagt gccagaaaa
//
LOCUS       DAJSMK010000010        51220 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.010, whole genome shotgun sequence.
ACCESSION   DAJSMK010000010 DAJSMK010000000
VERSION     DAJSMK010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 51220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.010"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            330..1175
                     /locus_tag="ON488_000607"
     CDS             330..1175
                     /locus_tag="ON488_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3230825.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="ON488_000608"
     CDS             1456..2676
                     /locus_tag="ON488_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HCR3230826.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="ON488_000609"
     CDS             2673..5393
                     /locus_tag="ON488_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3230827.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="ON488_000610"
     CDS             5377..6321
                     /locus_tag="ON488_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCR3230828.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="ON488_000611"
     CDS             complement(6390..7400)
                     /locus_tag="ON488_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCR3230829.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="ON488_000612"
     CDS             complement(7580..7924)
                     /locus_tag="ON488_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCR3230830.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="ON488_000613"
     CDS             complement(7917..8351)
                     /locus_tag="ON488_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HCR3230831.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="ON488_000614"
     CDS             8489..9226
                     /locus_tag="ON488_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230832.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="ON488_000615"
     CDS             9219..10430
                     /locus_tag="ON488_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230833.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="ON488_000616"
     CDS             10634..11416
                     /locus_tag="ON488_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HCR3230834.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="ON488_000617"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="ON488_000617"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HCR3230835.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ON488_000618"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="ON488_000618"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HCR3230836.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="ON488_000619"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="ON488_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HCR3230837.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="ON488_000620"
     CDS             15018..16067
                     /locus_tag="ON488_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HCR3230838.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="ON488_000621"
     CDS             16064..16342
                     /locus_tag="ON488_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HCR3230839.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="ON488_000622"
     CDS             16317..16787
                     /locus_tag="ON488_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HCR3230840.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="ON488_000623"
     CDS             16804..17106
                     /locus_tag="ON488_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230841.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="ON488_000624"
     CDS             17123..17494
                     /locus_tag="ON488_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HCR3230842.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="ON488_000625"
     CDS             17466..17825
                     /locus_tag="ON488_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230843.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="ON488_000626"
     CDS             17997..19004
                     /locus_tag="ON488_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3230844.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="ON488_000627"
     CDS             19029..20213
                     /locus_tag="ON488_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HCR3230845.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="ON488_000628"
     CDS             complement(20650..22233)
                     /locus_tag="ON488_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCR3230846.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="ON488_000629"
     CDS             complement(22811..22954)
                     /locus_tag="ON488_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HCR3230847.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="ON488_000630"
     CDS             complement(23177..23656)
                     /locus_tag="ON488_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCR3230848.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="ON488_000631"
     CDS             complement(23729..24013)
                     /locus_tag="ON488_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230849.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="ON488_000632"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="ON488_000632"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="ON488_000633"
     CDS             complement(24357..25643)
                     /locus_tag="ON488_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HCR3230850.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="ON488_000634"
     CDS             25781..26452
                     /locus_tag="ON488_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HCR3230851.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="ON488_000635"
     CDS             26418..26906
                     /locus_tag="ON488_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HCR3230852.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="ON488_000636"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="ON488_000636"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HCR3230853.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="ON488_000637"
     CDS             27867..28631
                     /locus_tag="ON488_000637"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HCR3230854.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="ON488_000638"
     CDS             28864..31077
                     /locus_tag="ON488_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HCR3230855.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="ON488_000639"
     CDS             31088..31534
                     /locus_tag="ON488_000639"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HCR3230856.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="ON488_000640"
     CDS             31705..32964
                     /locus_tag="ON488_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HCR3230857.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="ON488_000641"
     CDS             complement(33053..34000)
                     /locus_tag="ON488_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCR3230858.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="ON488_000642"
     CDS             34394..35686
                     /locus_tag="ON488_000642"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HCR3230859.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="ON488_000643"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="ON488_000643"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HCR3230860.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="ON488_000644"
     CDS             37579..38454
                     /locus_tag="ON488_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCR3230861.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="ON488_000645"
     CDS             38720..40603
                     /locus_tag="ON488_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HCR3230862.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="ON488_000646"
     CDS             complement(40678..40962)
                     /locus_tag="ON488_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCR3230863.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="ON488_000647"
     CDS             complement(40952..41686)
                     /locus_tag="ON488_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HCR3230864.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="ON488_000648"
     CDS             41815..42438
                     /locus_tag="ON488_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HCR3230865.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="ON488_000649"
     CDS             42630..43751
                     /locus_tag="ON488_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HCR3230866.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="ON488_000650"
     CDS             43758..46886
                     /locus_tag="ON488_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HCR3230867.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="ON488_000651"
     CDS             46905..50099
                     /locus_tag="ON488_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HCR3230868.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="ON488_000652"
     CDS             complement(50245..50952)
                     /locus_tag="ON488_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCR3230869.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        16760 a         8948 c        10638 g        14874 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt
//
LOCUS       DAJSMK010000011        47782 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.011, whole genome shotgun sequence.
ACCESSION   DAJSMK010000011 DAJSMK010000000
VERSION     DAJSMK010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.011"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(391..2772)
                     /locus_tag="ON488_000653"
     CDS             complement(391..2772)
                     /locus_tag="ON488_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HCR3230870.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2762..3409)
                     /gene="recU"
                     /locus_tag="ON488_000654"
     CDS             complement(2762..3409)
                     /gene="recU"
                     /locus_tag="ON488_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HCR3230871.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3473..4012
                     /locus_tag="ON488_000655"
     CDS             3473..4012
                     /locus_tag="ON488_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HCR3230872.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            4102..4521
                     /gene="gpsB"
                     /locus_tag="ON488_000656"
     CDS             4102..4521
                     /gene="gpsB"
                     /locus_tag="ON488_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HCR3230873.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4543..4910
                     /gene="rnpB"
                     /locus_tag="ON488_000657"
     ncRNA           4543..4910
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="ON488_000657"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            5119..6285
                     /locus_tag="ON488_000658"
     CDS             5119..6285
                     /locus_tag="ON488_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HCR3230874.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6331..7827
                     /locus_tag="ON488_000659"
     CDS             6331..7827
                     /locus_tag="ON488_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HCR3230875.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7908..8591
                     /locus_tag="ON488_000660"
     CDS             7908..8591
                     /locus_tag="ON488_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCR3230876.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            9236..10426
                     /locus_tag="ON488_000661"
     CDS             9236..10426
                     /locus_tag="ON488_000661"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HCR3230877.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10528..11481
                     /locus_tag="ON488_000662"
     CDS             10528..11481
                     /locus_tag="ON488_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HCR3230878.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            11550..12899
                     /locus_tag="ON488_000663"
     CDS             11550..12899
                     /locus_tag="ON488_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3230879.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(13082..13405)
                     /locus_tag="ON488_000664"
     CDS             complement(13082..13405)
                     /locus_tag="ON488_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230880.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13534..14697
                     /locus_tag="ON488_000665"
     CDS             13534..14697
                     /locus_tag="ON488_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HCR3230881.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14767..16116
                     /locus_tag="ON488_000666"
     CDS             14767..16116
                     /locus_tag="ON488_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCR3230882.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(16161..16592)
                     /locus_tag="ON488_000667"
     CDS             complement(16161..16592)
                     /locus_tag="ON488_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3230883.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            16980..19622
                     /gene="alaS"
                     /locus_tag="ON488_000668"
     CDS             16980..19622
                     /gene="alaS"
                     /locus_tag="ON488_000668"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HCR3230884.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVCEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19822..20418
                     /locus_tag="ON488_000669"
     CDS             19822..20418
                     /locus_tag="ON488_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCR3230885.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20540..21688
                     /locus_tag="ON488_000670"
     CDS             20540..21688
                     /locus_tag="ON488_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCR3230886.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21726..22139)
                     /locus_tag="ON488_000671"
     CDS             complement(21726..22139)
                     /locus_tag="ON488_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HCR3230887.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            22218..22649
                     /locus_tag="ON488_000672"
     CDS             22218..22649
                     /locus_tag="ON488_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HCR3230888.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22748..22981)
                     /locus_tag="ON488_000673"
     CDS             complement(22748..22981)
                     /locus_tag="ON488_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HCR3230889.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            23164..24834
                     /locus_tag="ON488_000674"
     CDS             23164..24834
                     /locus_tag="ON488_000674"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HCR3230890.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            24981..25367
                     /locus_tag="ON488_000675"
     CDS             24981..25367
                     /locus_tag="ON488_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230891.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            25354..26052
                     /locus_tag="ON488_000676"
     CDS             25354..26052
                     /locus_tag="ON488_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCR3230892.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            26057..26521
                     /locus_tag="ON488_000677"
     CDS             26057..26521
                     /locus_tag="ON488_000677"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HCR3230893.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            26518..27429
                     /locus_tag="ON488_000678"
     CDS             26518..27429
                     /locus_tag="ON488_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCR3230894.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            27664..28203
                     /gene="pyrR"
                     /locus_tag="ON488_000679"
     CDS             27664..28203
                     /gene="pyrR"
                     /locus_tag="ON488_000679"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HCR3230895.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            28217..29500
                     /locus_tag="ON488_000680"
     CDS             28217..29500
                     /locus_tag="ON488_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HCR3230896.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            29513..30439
                     /locus_tag="ON488_000681"
     CDS             29513..30439
                     /locus_tag="ON488_000681"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HCR3230897.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            30458..31738
                     /locus_tag="ON488_000682"
     CDS             30458..31738
                     /locus_tag="ON488_000682"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HCR3230898.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            31743..32819
                     /gene="carA"
                     /locus_tag="ON488_000683"
     CDS             31743..32819
                     /gene="carA"
                     /locus_tag="ON488_000683"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HCR3230899.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            32824..36009
                     /gene="carB"
                     /locus_tag="ON488_000684"
     CDS             32824..36009
                     /gene="carB"
                     /locus_tag="ON488_000684"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HCR3230900.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            36063..36839
                     /locus_tag="ON488_000685"
     CDS             36063..36839
                     /locus_tag="ON488_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HCR3230901.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            36836..37768
                     /locus_tag="ON488_000686"
     CDS             36836..37768
                     /locus_tag="ON488_000686"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HCR3230902.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            37765..38481
                     /gene="pyrF"
                     /locus_tag="ON488_000687"
     CDS             37765..38481
                     /gene="pyrF"
                     /locus_tag="ON488_000687"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HCR3230903.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            38488..39117
                     /locus_tag="ON488_000688"
     CDS             38488..39117
                     /locus_tag="ON488_000688"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HCR3230904.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            39105..39419
                     /locus_tag="ON488_000689"
     CDS             39105..39419
                     /locus_tag="ON488_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230905.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            39457..40098
                     /locus_tag="ON488_000690"
     CDS             39457..40098
                     /locus_tag="ON488_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCR3230906.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            40141..40833
                     /locus_tag="ON488_000691"
     CDS             40141..40833
                     /locus_tag="ON488_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HCR3230907.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            40830..41732
                     /locus_tag="ON488_000692"
     CDS             40830..41732
                     /locus_tag="ON488_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR3230908.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(41890..43596)
                     /gene="efbA"
                     /locus_tag="ON488_000693"
     CDS             complement(41890..43596)
                     /gene="efbA"
                     /locus_tag="ON488_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HCR3230909.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            43786..44409
                     /locus_tag="ON488_000694"
     CDS             43786..44409
                     /locus_tag="ON488_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230910.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            44859..45908
                     /locus_tag="ON488_000695"
     CDS             44859..45908
                     /locus_tag="ON488_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3230911.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            45905..46786
                     /locus_tag="ON488_000696"
     CDS             45905..46786
                     /locus_tag="ON488_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230912.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            46789..47559
                     /locus_tag="ON488_000697"
     CDS             46789..47559
                     /locus_tag="ON488_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3230913.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
BASE COUNT        15383 a         8399 c        10354 g        13646 t
ORIGIN      
        1 ataaaaaaag atggtgcaga caaattatga taattaagca tactatcaga taactcaaaa
       61 tgaagccttc tttcaaaaaa ttattcaaaa ccatatattg tattttttat ttgataataa
      121 caatgggatt attaagaagt ggcactaaat aaaagactag tgtgtattta gccgatttaa
      181 ttataaacaa gtaaatggat aaagtatatg taatgataaa agaaaaatgg attttctaat
      241 ttttaagcta aatgttagat cacacatgta tatgctggat agtcttataa aaaatcatgt
      301 aatacagctt ggtacatgat ttttatttgt agctgttttt tacatagaca caaaaaagaa
      361 accacgcttg tagacgtggt ttctttttta ctatctgttt ccagaagctg aggtgctgct
      421 ggatggtgta tggtcatttg cagcatccgc tccgctagtt gctggctcac tggaagaagc
      481 aggaggagca gatgaagacg gtgtcgagct ttcttcggat gaagaagaag gaaccgttgt
      541 tgaagacgct ggctcgcttg tttctgctgt cgtgctttct tttgaggact cagcagttga
      601 ttcgctttga ctagtagagc tagagctttg agtcgttgtc tctgttgttg agcttccagg
      661 agtctggaca tagctggaag atggaatagt tgttgatggt gtaattgcat tcgatctagc
      721 tgtatattga tctttgtagt acagttcacc gcccacacga attaatccgc ttggcatctc
      781 ccagtctgta tttgtcacgt tagctgaaac atactgcata agctcgcgat aaacatcaga
      841 ggctacgtgt gacgattctg aagtgacagg tgtcattttt ttattgtaac ctgtccacac
      901 ggaaatcgaa taatttggcg tatagcccgc aaataggata tctggataca ccccagaaga
      961 aataccaagt tttgcatact cgtcatctgt gtaattggat gttccggtct taccggcttg
     1021 atataaccca gcgatttgcg cattcgtacc agttccttca gtgatcgtat cttttaaaat
     1081 gtctgtgatc atataagctg tttctggaga catggctgtt tttccatctg gctcataagt
     1141 ttcttctgtt ccgtcttgga agacgatttt attaacatat tgaggtttgt aataagtccc
     1201 tccattggcg aaagccgcat aggctgctgc catttttaag gaagaagctc cgtattttgt
     1261 cccatcttgt tcttccgtat tactagagat cgcattcgat tgatggatcg tactgtattc
     1321 gatcccaaga ttttttaaga aagaagccac tttatctgaa ccgacttcat tgaataattt
     1381 gactgctgga acattacggg ataagtaaag tgcttggcgt aaagtaatgg tgcccatata
     1441 ttgattatcc cagtttccta caggagtcga agtcccttca tagttatacg gtgcgtcagt
     1501 aatagttttt ccagtagaat atttcaaata ttcaaaagct ggtccgtaat ctgtgacagg
     1561 tttcatcgta gaaccaaaat cacgggaagt attcactgct aagttgttgc ctaaagttac
     1621 gtcttctgcg atgtgacgtc cgccaatctg ggcttttact ttcccggtat tggtgtcgat
     1681 aagggtggag gcaacttgca tctcgtcgtc tgggtaagag acatactgat ccgtgttgac
     1741 gatatcatat agtttctttt gggcgtccag atccaaattc gtataaatct ctaaaccgtc
     1801 tgtgtagaca ttcttatctg ttttttcttg tacttcattg atgacttctt tgacataatt
     1861 atcgacgatc ttagtattgt catcggattg agttagttct tgcagaccat ccgttaccgg
     1921 tacattaaca gcttgatcat attctgtttg agagattttt tcgttttgaa gcatcgtata
     1981 caaaacagta tctcgtcttt tcttcgcctg atctggataa acataaggat cataggcgga
     2041 aggggcttga ggcatcccag caagcaatgc tgtttgcggt aaagaaagtt ctgataattt
     2101 cttaccaaag tacatctcag aagctgtctc catcccgtac aagccgtttg acatatacac
     2161 tttatttacg tagtaggtca agatctcttg tttcgatttt ttttgttcca atcttacagc
     2221 catccacgct tcttgggcct tgcgtttcag agtctgatcc tcggcactgg tggagaagaa
     2281 ggaaagtttg atcaattgct gtgtcaaagt acttccgcct tgcagtccgc cagaggtaaa
     2341 gttagagagg gcagaaccga tgatccgaat agggtcaacc ccgatgtgtt tataaaaacg
     2401 gcgatcttct accgacacga tcgcatcttc taatgttttc ggtaattcat tcgcagaaat
     2461 tttttcacgc ttttctgcgc ctaaatcttc gaatagttcg ccatcttgtg tatatagttt
     2521 ggaagatacg gtagcgtcta attttttatc cgtcaattcg ggcgcatctt ttgcgtaata
     2581 ccagaaaagt cctacacctg ctaaaaagag gatacagaaa aatgagagta ttcctaaaag
     2641 gatcttgata aataatcctt ttttatgtgt tccagaggac tttccagaac ctttgccaga
     2701 attcttcttc acactctttt taggagtagg ctgtttctgt cgtctagagc ttctagtttg
     2761 ttcatttgcc attcttgctt tctccttcaa tagataatgt tgataaatag aagtcaaccg
     2821 cgtccaaata aggaatccgc ggagaaatac cagttttgat ctctattcct agttcttcga
     2881 tcaaagataa aggtagtgat ttgcgtcctt tttccttttg ggcgtcccag taagcaatca
     2941 aatgaacact attcaaataa aaacagcgct tcaaagacga aaaccataac aagacaaagc
     3001 agaccccatt ttgttcgagg catgctttca tatgttcgat ttgatgggca tggaagtttt
     3061 taaagggaaa agatgttttg ttcttggttt cttttgcttc aaagtccaag taaaagcctc
     3121 gatagacgcc attatagtct gtagttgagg cttgggtaaa gtaggcttcc ttgatcacag
     3181 cagcacttct cttaggatag tctactttca cgatttggat aggggtaggc tttttatgga
     3241 taaccgccaa cccgcgggaa agataatatt tattactttc attgattgct tcttcaaagc
     3301 gcatcccccg attgccgaat tcagtgatct gatttctttt ttcttgaatt ttttcgacgg
     3361 gagaggcatt cttataataa ggttggccat ttggatagcg caataccatc tttaatcaca
     3421 ctcctaggcc acattatagc aaaaaagcgg atagaaagaa aaggaatctg agatggataa
     3481 gtcaaaagta atctatgtgt ctgggtatcg aagtttcgaa ctcggtgttt ttaaagaaaa
     3541 tgatcctaaa atccaagttg ttaaaaatgt tttaaaaaaa gaactccatc agttagcaga
     3601 agaagggctg gaatgggtac ttgtcagtgg gaatttgggc gtcgaactat gggctgtgca
     3661 aatagtagcg gaattgaaag aagaatatcc ggaactatct cttggtattt tgtatccttt
     3721 ttctgatttt ggtaataact ggaatgaagg gaaccaagaa aaaaaacaat tagcagaaca
     3781 attagcagat tatgtcgaag ctgttagcca tcaaccctac caatcaccta gtcagctaaa
     3841 gaatcacact cgttttatac ttgagcatac agtgggctgt ctgctgatct atgatgaaga
     3901 attccctgga aaaacgaagt atttttttga agatgcacag aattaccaag cagatcatcc
     3961 ctacgaaatt cggctgatca gtatggacga tcttcaaaat tttagtgaat aatcgatatt
     4021 gtgtttgatt tatcaacttt tttcctatac aatgaaaaag gtagaaatgt tattacgtaa
     4081 atgaaaacta gaggtgtaaa tatggcgaat ttggtttata gtcctaaaga cattttacaa
     4141 caagaattca aaacaaaaat gcgcggctat gatcccgttg aagttgatga attcttagac
     4201 aatatcatca aagattatga aacttacagc aaagaactcc ttgctttaca agaagaaaac
     4261 gatcgattga gtgcaaaagt agctcaatta tctaaaactc aaggagcagc tcaaacacgc
     4321 gtgcaacaaa cagaggcacc aaagagcgca gcagtgacca attttgatat cttaaaacgc
     4381 ttgtcaaatc ttgaacgtga agtatttggt aaaaagcttg atcaacaagc aagtgcagtc
     4441 aaaccagcac aacctaatcc aaataactac acaaatgcag acacaagctt agatgataat
     4501 gaaaaaacac gtcaatttta atttttgatt aatgaatttg cggttttcgg gtaatcgcgg
     4561 tctgacttga tcaggctgag gaaagtccat gctcgcacag gctgtgatgc ctgtagtgtt
     4621 cgtgcttagc gaaaccataa gctaaggtac tctttggagt aacggcagga aaacaagcta
     4681 aggcttcggc tatgcttaag tatccttgaa agtgccacag tgacgaagcg gctggggaaa
     4741 cccatccggt ggaacgcggt aaacccctcg agcgagcaac ccaaacaatg gtaggggcgc
     4801 tttttgtctg gaagaagaac aggacaaaaa ggcagtataa ctgcagatag atggttaccg
     4861 ctttgttttt tctccctgga aaagcaaagt acagaacatg gcttatagaa aaccgcaaac
     4921 atcagggaat taggtcgtga caaaagtaat gcgttataag aaacaagaaa aacatttgaa
     4981 agctattttt caatacttca gatgaatcgt tcttattaca aaacaaactt ttgtatcacc
     5041 ggttattcgg aatttgagta aaagtgtggg gtaggactga tgtcccacct ccttttttta
     5101 taaataagga gattgtgtat ggaaaaaaac aggaagttca acctcgtcgc aactgcggca
     5161 agcgggctag aagcactggt tggtaaagaa ttaagagatc ttggaatcga atgccaagtt
     5221 gagaacggac gtgcacgttt tgaaggaaca atggaaacga tcgctacagc taatttatgg
     5281 ttacgtacag cagatcgagt aaaaatcgtg gttggggaat tcgatgcgta tacgtttgat
     5341 gaattgtttg aaaacgtaaa agcattgcct tgggaagatt ttcttccact agatgcagct
     5401 tttcctgtag ctggaaaatc gatcaagtcg aaactatata gcacacctga ttgccaagcg
     5461 atcacaaaaa aagcaatcgt tgaacgtctc cgtacctatt atcaccgtcc agcttctgta
     5521 ccactgacgg aaactggcgc acattttcag ttggaagtag ctttgctgaa agaccatgtg
     5581 atggtaactc tggatacgac aggaccaagt ttattcaaac gtggttatcg cttagaaaaa
     5641 ggtggagcac cattgaaaga aaacatggca gcagcactta ttatgttgac aaattggcga
     5701 aaagaccgtc cattttatga tcctgtatgt ggttcaggta cgctttgtat tgaagcagcc
     5761 ttaataggcc ataatatcgc accaggattc aatcgtgagt ttgcttgcga atcttgggat
     5821 tggttcagtc aagaaatcat ggaaaatgtt cgatcagcag ccgaagaaaa agcagattat
     5881 gatattgaat tagatattac tggttcagat atcaatggac ggatgattga aattgccaaa
     5941 gccaatgcag aagaaatcgg attaggctct tcgattacct ttaagcaaca agcagtcaaa
     6001 gacttcaaaa cggataaaga atacggggtc atcgtggcta atccgcctta cggagaacgt
     6061 ctaggagaag aagaaactgt tcggaaatta tataaagaaa tgggcgatgt attccgtcca
     6121 ttaaaaacat ggagtaaata tatcttgact agcgacttag cgtttgagga attttacgga
     6181 caaaaagcaa ccaaaaaaag aaaattgtac aatggtgcat tgcgtacgga tctattccag
     6241 tattggggaa ctcgtccgcc tagaaaaaaa gagaaagacg aataatctta ctaattgatt
     6301 cattcaattg gatgtttgga ggaataggga atgaaagaaa aagagttttt acaagaagta
     6361 aaagaaatca atcttctaca acaagcttta ggaatcctcg attgggatac acaaacaggt
     6421 atgcctgaaa aagctagtgc ataccgaagt gaagtagaca gctatcttta cagcatttat
     6481 ttttcaaaaa aaatcggtcc aaaaatcaaa gaagccattc gctatttttc tgaacatccg
     6541 gaagaattgt cggaagttgg aactgccgtt tttgccaaag taaaagaaga gtatgatttg
     6601 gaacatcgcg taccggaaga tcttatgaga aaatatacag ctgccgtttc ttcagcacac
     6661 ggacaatggc aaaaagctag agaaacacaa caattttctg attttcaaca cgcattgaat
     6721 caaaatattg aattaacaaa acagttgata ccttactgga gaaaagatga aaagacgaat
     6781 tatgatgttt tgctgaatca atacgaaccc gggatgactg tcgaaatcct tgataaggta
     6841 tttgatcagc ttaaagaagg aattctttcg atccgccgta cgctccaaga aaaagggact
     6901 gaacctgaaa cagacttttt aaatcggaga atgacgaaaa aacaacagaa gagatttgta
     6961 gtgaaagtaa tcgaacaact tggttatgat tttagtcgtg gtcgtttaga tgacactgtc
     7021 cacccattta tgactggaat taatccgaat gatgcacgaa tcacgacacg atggaacgaa
     7081 acagatttca aaatggctgt ttttggagtg atccacgagg ctggtcatgg tatgtatgaa
     7141 caagacatcg atgataaata tgcgtataca ccggtttatg aaggtacatc aatgggtatc
     7201 catgaatcac aatcgttgtt taacgagatc attattggaa gtagtcgcag cttctggaaa
     7261 aagcaatatc ctttctttca agaatgtgca gaaggaacat tcgatgatat tccttttgac
     7321 aaattttatc gttcattgaa ccatacaaaa tcaagtttgg ttcgtatcga ggcagacagt
     7381 ttgacttacc ctctccatat catcattcgt tatgaaatcg aaaaaatgat tttcaatgaa
     7441 ggggtagatg ttgctgaact acctgaaata tggaatcaaa aatatgaaga gtatctggga
     7501 atacgaccaa caaatgatgt ggaaggcatc ctacaagacg ttcattggtc aggtgcaagc
     7561 tttggttatt ttccctctta tgcattaggg tacatgtatg cggcacaatt acttcattct
     7621 ttgcagcaag aaatagatgt ggaaaatgtt ctagcgtcag acgattattc tccaatcaaa
     7681 aactggatgt cagagcatat ccatcaatat ggtgcatcta gaaaaccaaa tcaattaatc
     7741 atggatgcaa cacatgaacc gcttaatccg caatacctga tcgactatat gaaagacctg
     7801 tattttaatg tatatcaggt aaaataaaat acaatttaca aagatagctg aaattcatct
     7861 aatctataga tgttttcagc tatttactta agaaagaagt ggaacgaatg gataaattac
     7921 aagtgatcgc tgattatagt atggaccaat tagcgcatga tcaaacagga catgggagcg
     7981 atcataccaa aagagttgtc aagttagctg aaaaaatttt ggagacggaa ccgcaggcag
     8041 accgctttgt gacgcttgca gcagcttacc tacatgatac gattgatgat aaagtcgtta
     8101 aaaatgagaa cgaggcaaag caacagcttc gtgtattcct tcgctctttg ccaatagtag
     8161 aggaacagat ctcgatgatt ttttccatta tcgaaaatat gtccttttct aaaaatctct
     8221 ctgaagcggc cgaactatct ctggaaggta agatcgttca agacgctgat cgtatcgaag
     8281 cattaggagc aatcggcatt ttgcgtactg cttatttcgg cggtggacat gggcacccga
     8341 tttttgatcc tgaactgtat ccgcaaacat tcaaggacaa agaaaattac cgaaaaggca
     8401 cgacagtgat caatcatttt tatgaaaaac tgttcttgct gtctgataaa atgaatactg
     8461 attacggata tgaagaagcc aaacgaagag aaaccttcat gcgtgaattc ttagaagaat
     8521 tttttctgga atggtctatt gacgatgaaa attttactcc agacaattgg atcaaaaata
     8581 acaaaaaatg atggaggttg tgacagaagt ggtcagctcc aagatatttc ggatcatttt
     8641 ccgtaaaagt tacttctgga acactgttta ccaagaggtc gtgagcctgc cgttcagctc
     8701 cgagtcacaa ggaacaattt caaaaaatag cttctcgtgt ttgatgaata ttgtaacttg
     8761 tgattcggaa ttggcaggag aacaccgttt attcggaaga ataggactgt gacaagactt
     8821 ttgtcacagt ccttttttcg aattcaacaa gtaaaacttt taagaaatat tcagagagta
     8881 aaattaaaaa ttgctgataa acgaagatgg aaattttatg tatttttatt ggtctatgca
     8941 ataaataaat taaatattca gaatacaatt gattttaacg aaagggcttc tatcaatggt
     9001 tgtgttgtat ttatctgccc aggtagagta aaatagatca ttatctaaaa ggtaattgtt
     9061 catactatat aagtcatttg aaagtaaaaa gatactgtaa ataaaaaatg tggttaaata
     9121 attctcataa tcagtgtaag cgttatcaaa aatatagcat acttgctttg tagatgaatg
     9181 acacgatata tgtttggtat gttctgcaag acagatgaat atggaggtgg agacaatgtc
     9241 ttccaaagaa ctaacaatgt atttagagaa agaattggat caactgaaag aaaaggggtt
     9301 atacaatacg atcgacatac tagaaagtga aaatggtgct tgtatcatcg tagacggaaa
     9361 aaagatgatc aatctagcat ccaacaatta tcttggattt gccaatcgcg aagaattgaa
     9421 aaaagcatgt attgaagcaa ccgaaactta tggtgtagga gcaggagcag tccgaacgat
     9481 caatggttcg ctgaaaatcc atcagcaatt agaagaaaaa atcgcagaat tcaaagggac
     9541 agaagcagca atcgcctttc aatctggatt caactgcaat atgggcgcta tctctgcagt
     9601 aatgacaaaa gaagatgcta tcttatcgga tgaattaaac catgcatcta ttattgacgg
     9661 ttgccgctta tccggagcaa aaatcatccg aattaaacat caagatatga aagaccttga
     9721 gaaaaaagca aaggaagcga tagaaagtaa gaaatataaa aaaatcatgt atatcacaga
     9781 tggtgttttc tccatggatg gagacattgc acgattgccg gaaattattc cgattgttga
     9841 aaaatatgga ctgatcacct acgtcgatga tgcgcacggc tcaggcgtaa ctggaaaagg
     9901 tgcaggaacc gtcaagcatt ttggattaag cgacaaaatc gatatgcaaa tgggcacgtt
     9961 atcgaaagct ataggtgttg ttgggggtta tgtagctgga tcgaaaacac taatcgactg
    10021 gttgaaagct agaagtcggc cattcctatt ttctacttcg ctaactccag gtgcagctgc
    10081 agctgcattg gcttcgatta ctttgatgca agaacatccg gaacttgtcg aaaaagtttg
    10141 ggaaaatgct aattatttta aagaagaatt gaaaaaagta ggctataaca tcggtatgtc
    10201 tgaaacacct attactccag tcattttggg agacgaaaaa gtgactcaga ctttctctaa
    10261 gaagctgatc gaacatggga tttatgctaa accaatcgtt tatccaactg tgcctcttgg
    10321 gacaggcagg atcagaaata tgccgactgc ggaacatacg agggaaatgc ttgatgaagc
    10381 agtagcagtt tatcaaaaaa taggaaaaga aatggaaatt atttaactaa atttagtttt
    10441 ttcgtctatt taaaattaga gaacatgttc acgcatatat tgttaatcat ctgaagatag
    10501 tagtaaaaaa gatcagggag gatcatcatg aaaaaagtat tggtgacagg atgtttagga
    10561 caaattggtt cagagttgat cacacggcta cgtcaagaac taggcagtga aaatgtcatt
    10621 gcgacagata tacgcatgcc tgaagtcatt gagaaaaacg atatctttga gatcctagat
    10681 gtaatggatt acgaaaaaat gcgcagcata gcagaacaat atcaagtgga cacattgatt
    10741 catttggctg ctcttttgtc agctgttgca gaagcaaaac cacaattagc ctggaatttg
    10801 aacgtgactg ggctggtcaa tgcattggaa gtcgctagag aattccagct gaaatttttt
    10861 acgccaagtt caatcggcgc gtttggtcca aatactccaa aagatcatac cccacaagat
    10921 actcttcagc gtcctacaac catgtatggg gtaacgaagg tagctggaga actactatgt
    10981 gattattatt atgtgaaata tggcgtagat actcgtggtg tccgtttccc tggattgatt
    11041 tcttatgcaa ccttgccagg aggcggtacg acagactacg cagtcgatat ttattattca
    11101 gcaatcaaag aaggaaagta cactagtttc attgatcaag gtacatcaat ggatatgatg
    11161 tatatgccag atgcgatcga tgccattata aaactcatga atgcagatcc tgatcgattg
    11221 gttcatcgaa atgccttcaa tatatcggcg atgtcttttg acccggaaga gatcaaagca
    11281 tctattcaaa aaatcatacc agattttgaa atggattatg atgtggatcc tgtacgtcag
    11341 tcaatagcag aatcttggcc aaattcacta gatgtttctt gtgcgcaaga ggaatggggc
    11401 ttttcgccga aatacgactt agatgtgatg acaaaggata tgttggaaaa actgaaagaa
    11461 aaattggtag agacggtata aaacaagaac cacatccaaa aagtttttta tacttttggg
    11521 attggctatg gtatgaaagg ggacaaggga tggaagaata tcaagccacg ccagtaaaag
    11581 aagtaaaaat agaaaatgaa ttaaaacgta cgatgggatt ttttactgct ttatcgactg
    11641 ttatgggcac agtgatcggt gcaggggtat tttttaaagc cgcaagcgta gcagaagtta
    11701 caggatccgc cagtttgcat atgttttctt ggtttctcgg tggtatgatt tctgtctgtg
    11761 caggactaac aggagctgaa ctggcagctg ctattccaga aacaggaggg atgattaaat
    11821 atatcgaacg gatttacgga aatacagcag cttttttatt gggctgggcg caagtcgtga
    11881 tttattttcc agcaaatgta gcagccttgt cgatcatttt cggtacacag ttcgtcaatc
    11941 tatttggtct ttcccagtca atgattgttc ccgtagctgt tacagctgct gtatcgatcc
    12001 tgttgatcaa ttttttaggt tctaaagctg gaggggcttt tcagtcgatt acgcttgtct
    12061 gcaagcttat tcctttgttt gtgatcgtca ttttcggttt gttccgacaa gaaggagtag
    12121 acttccaact gtttccgatc caagcaggag aaaatctttc atttttctca gccttgggag
    12181 cgggcttgct agcaacgatg ttcgcatacg acggttggat acacgtagga aatatttcgg
    12241 gagaattgaa aaagccggcg aaagatttgc caaaagcaat ttctttagga atcatcggaa
    12301 tcatgatcgt ttatttatta gtaaatgcgg tgttcttaag aaccgcatct atcgacggag
    12361 tcgcaggaaa cagcaatgcg gcaagtgacg ttgcaaaaat gatttttggc ggcttcggtg
    12421 gaagactggt cacagttggt atcttgattt ctgtttatgg aaccatcaat ggctataccc
    12481 ttactggaat gcgtctccct tatgttatgg caaaagaaaa caacctgcct tttagcaagc
    12541 tctttgctaa acttcatgat aaaactaaag ttcctgtagc cgcaggtatc ttagagctag
    12601 tcatcgctat tggcatgatg atgatcggtg gttttgatac actaacggat atgctgatct
    12661 ttgtcatttg gattttttat acgatggtct ttgttggtgt cattcttctt cgtaaaaaag
    12721 aacctgattt gtttcgacca tacaaagttc caatgtatcc gtttattcca ctagtagcaa
    12781 tcattggagg gacttttatc gtatcaagca cgcttatcac tcagaccttt ttagcttcga
    12841 tggggatagt attgacactt gctggtatcc cgatttatct ctatttaaaa cgtagatagc
    12901 taaaacattc gaattttatt agaactgcac ttctctgcca aacaaaatat tttatttaaa
    12961 tgaggagtac gtggaagaaa tgtcaaaagt actcgttaat tttgatcacg taaatgtcgt
    13021 tttgtctacg atgaaatagc aaagtaaaag acagaaatcg ggctcaaccg atttctgtct
    13081 tttactttga tttgcgtaac tgaactattc ggcgtacgcc gcgataaata tttaataaaa
    13141 ccaagcaacc agaaatgaaa atgggaagcc aaatcagata gacagggtag ccaagcactt
    13201 tagacaaagc atgtggagtc attttatcca tttcaagaag tgcttgctgc caagtctgaa
    13261 gattgaagac tagcatgaaa cccgaaataa tcaggagaat aaatcctaaa taatgaattg
    13321 tagttctttt tcttacataa gcgatcgtag cataaaggaa cagtaaaaaa ataggtacgc
    13381 caaaaacaaa gtacatattc agcatctcga cacccccttt gtgtttatct tactttactt
    13441 tgaaagaaat gagaaataat agcctcgtta cttgcttgaa acagcaaagg actgctaaga
    13501 taagagagat acaaagaatc aaggaggagt catatggcaa gttatatcga accgattcgt
    13561 tttgcgctga ttgtttttcc atttttagcc ttagcgatct catctgtttt ttttatttat
    13621 gaatatcgaa agtatggaac atttctagta acaagggcag ttattttgta ttctttcgtt
    13681 ttttatttat tgtgtgcgta ttttttggtg atcttaccac ttccggcaaa ggagacggtt
    13741 gcccaaatga cagggccaaa gatggagctg catttatttg cttcatggca acatttcaga
    13801 gacaacacgg tattggtctt gtctgaacct agtacctacc tgccggcaat gaagcagagt
    13861 gtatttttgg aaccagcttt taatgtttta ttactcatac catttggcat ttatttaaga
    13921 tattatttcc ggctttcttt tatgaaaacg atgattgcta gtttctgcct ttctctattt
    13981 tttgaattga cgcagctaag tggactttat tttatctacc caagaccata ccgcttattt
    14041 gatgtgaatg atttagtgac aaatacattg ggtggaatca ttggttttgt cgttacgccg
    14101 ttatttacat ttatgcttcc tacaagaaga cgaatggatg aactttctta tgaaaaagga
    14161 aagactgtct cattgactcg acgcttggtc gcttatttga tcgactggac atttttatct
    14221 cttattaatt tggtagcggc gattttcttt aaaattgcgt tcgattcagg ggcagttact
    14281 tctcatatct ggtggctttt attagaagta ggggtatatt ttatgattgt accgtttata
    14341 accaatggat ggacacttgg caaaaaaatt gtgcgtatcc gtttggtgga agaagaccgc
    14401 gaacgaattt ctttaaaagc attgatgatc cgctacgggt atctgtactt tcttttttat
    14461 ggtttaagct ggttggggca gttgcttcag caaatcatga attcgacaac gaatacggtg
    14521 ttgcagatga gtgcagtatt catttctctc ggtgtcttgt tactacaagg tatttttatt
    14581 ttaaatatct tgctatcatt tttgagaaaa aaacggattc tgttttatga aaaagctagt
    14641 cacacatata ctgttagcac gattggccaa acaaaggatg atgattctcg aaattagctg
    14701 agcaaaaacg ctttgtctgt gttataatgc caaagtcgtg ataatttaaa gagaagaggt
    14761 gcacgaatga ataattttga tatattccgc ttcaaaccgt ttatcaatga agcgttaacc
    14821 gcaaagggct tcaaacagcc cacagaggtc caggaacgtt tgattccttt aattgcaaaa
    14881 ggaaaaaata tcattgggca atctcaaact ggtacaggaa aaacacatac gtttttgttg
    14941 cctttgtttg aaaaaatcaa tgcagaaaaa gaggaagtac aagttgttat tacagctcca
    15001 agtagggaac tagctgcaca gatctatgaa gcagctacac aaatcgctaa attttctaca
    15061 ccggagatcc gtgtctcgaa ttttgtcggc ggtacagaca aacagcgtca attaaatcgt
    15121 ctgcatcacc aacagccaca ggttgtagta ggcacgcctg gtagaatatt agacatgatg
    15181 aatgaacaag cgctgaagat tcacaccgca tttgcatttg ttgtcgatga agcggatatg
    15241 acattggata tgggtttttt aaatgaagta gaccaaattg caagtcgatt accagaaaag
    15301 ctgcagtttt tagttttttc tgccactatt ccagaaaaac ttcgtccatt cttacgaaaa
    15361 tacatggaaa atccaatcat tgaagaaatc aaaccaaaag cagttatttc tgaagacatt
    15421 gaaaattggc tgatttcaac aaaaggtaaa gatgagaatc aaatgattta tcaactgctg
    15481 acaattggtc atccttattt agcaatcgta tttgccaata caaaacagca tgtggatgaa
    15541 attgccgatt acttgaaaaa ccaaggcttg aaagtagcaa agattcatgg agacatcacc
    15601 ccaagagaga gaaaacgagt gatgcgacaa gtacagaatc tggagtatca atatgttgta
    15661 gcgactgatt tagctgctag agggatcgat atcgaaggtg tctctcatgt tattaatgca
    15721 gaaattccag aagatctaga cttctttatc catcgtgtcg gacgtactgg acgtaatggc
    15781 ttaaaaggaa cggccattac gttatattcg ccaaatgatg agcaagccat tgatgcgata
    15841 gaaaaattgg gcgtctcatt tgaaccaaaa gaaatcaaaa acggggaaat cgtcaaaaca
    15901 tacgatcgta atagacgtgc caaacgagaa aaatcaaaag atgtattaga tcccacgctg
    15961 attggtcttg tgaagaagaa aaagaaaaag atcaagcctg gttataagaa aaaaatcgat
    16021 tgggcaattg cagaaaaaaa taaaaaagaa cgcaaaatcg aacgcagaca gcaaagccgt
    16081 actgctcgta aaaataagaa aaattcacat aaataaaaaa caagaggttg tgacaaaagg
    16141 cgtgtcacaa tctcttgttt ttaagctaga ctttttttca ttccgataca aagtacttca
    16201 tcttcaataa aaggttctgt gcaagtatga tacccttgtt tttcataaaa atctacagcc
    16261 gtcatttcag ctactacata actagtctga caaccttctg aaaccgcccg tttttcagca
    16321 gcttcaagca actgaccgcc taaccctttt cctcggtatt cttttgctac gcaaaatcgt
    16381 tccggcttga agcaagtagg tgttttcttt tcataacgca aagtagctac tggtcttttt
    16441 tgatcaagaa atagataata ggtttgttgc gggatatctt ttccgtcgaa ttctagttct
    16501 gcaggaatcc cttgttctaa tacaaaaact tgatatctca aaaagcagct agctgcgcgt
    16561 atccattcat ccgctccaac tatttttttc atcatattcc tccttgtcat gaatagcaga
    16621 gatgtattga ttcctttatt cttatcgtac caaaaatcgt ggagtatgac caaaaggaaa
    16681 tgaaaataaa aattgagata ttgacagtga tcaatagaat gcgtatacta aataagtacg
    16741 aaaaggatat gatttgtttt ttaagactca cagaaaattc tttcttggct gaaaaaagaa
    16801 tagtcactaa tcaaattgct ccctttttct attttggtag aaataccgac gcagctcagc
    16861 gttatcgagt ttaagaggta atgattacac atcattgcaa tcaaggtggt accgcgagtt
    16921 ttcgtccttg gctgtgatgg tgtttttttg tatttaattt atagaaagca ggtaatgaca
    16981 tgaaacaatt aagtagtgca caagttcgac aaatgtttct tgatttcttc caatctaaag
    17041 gacatacgat tgaacctagt gcgtctttga tccccgtgaa cgatccaacc ttattgtgga
    17101 tcaactctgg tgttgcaaca ttgaaaaaat attttgatgg ttcagttgtg ccagaaaatc
    17161 caagaatcac aaatgcccaa aaatctattc gaacaaatga tatcgaaaat gtcggtaaaa
    17221 cagcacggca ccatacgatg tttgagatgc tgggtaattt ttcgattggt gactatttca
    17281 aaaatgaagc catccactgg gcatgggaat ttttgactga tccaaaatgg atggcattcg
    17341 atccagaaaa actttatgta acagtttatc caaaagatac agaagcaaaa cgcatctggc
    17401 atgaagaagt tggcctgcca ctagatcaca ttattgatgt agaagacaac ttctgggata
    17461 tcggtgcagg cccatgtggt ccggatacgg aaattttcta tgaccgtgga gaagcttata
    17521 acgatttagc agaagacgat cctgaaaact atccaggagg agaaaatgaa cgttatttag
    17581 aaatctggaa cttagtattt tcagaattca accataagcc tgataacaca tttgaaccac
    17641 ttcctcataa aaacattgat acggggatgg gattggaacg catggtctca atcgttcaag
    17701 atgcgtcaac gaactttgag acagacttgt ttatgcctat tatccacgcc gtagaaaagc
    17761 taagcaaaca agtaaaatat ggtgaaaacc cagtaacaga tatttcttac aaagtaatcg
    17821 cagatcatat tcgcgccctt tcatttgcta ttggcgacgg tgcattgcca tcgaatgaag
    17881 ggagagggta tgtcttacgc cgtttgcttc gtcgtgctgt catgcatggg aaaaaattag
    17941 gtattgaaca agcattctta tatcgtttag tccctgttgt tggggaaatc atggtaagtt
    18001 attatcctga agtacttcaa caaaaagaat ttattgaaaa agttatccgt acagaagaag
    18061 aacgtttcaa tgaaacaatc aatgaaggtt tggaaatctt aaatcaagtg atccaagaag
    18121 taaaaaacga aaacgggacg actctagcag gaaaagacat cttcaaacta tacgacacat
    18181 atggcttccc ggtagaatta acggaagagg tggcagaaga tgaaggactg aaagttgatc
    18241 atgctggttt tgaaaaagaa atggatgcac aacgcgaacg tgctcgctct gcccgcagta
    18301 ctgaaaaatc aatgggggta caatctgctt tattgacaga tatcaaagta gaaagtaaat
    18361 tcattggata cacagaacaa gaatcagata gtcaattatt ggtcatcgtt aaaggtgagt
    18421 ctcttttgaa tgaagtcgca gaaggtgaag ctcaaatgat ctttgatcaa acacctttct
    18481 atgcagaaat gggtgggcaa gtagcggatc aaggatggat catgaatgaa gtatgcgaaa
    18541 tcgtagcagt tgttacagat gttcaaaaag cgcctaatgg tcaatttatg cacaccgtag
    18601 aagtaaaagc accaatgagt gaaggacaaa cctatcatct attgatcgat caatcgatgc
    18661 gcaatcggat catcaaaaac catacagcaa cccatctact gcacaaggca ttgaaagaag
    18721 tacttggcga gcatgcaaat caagctggtt ctttagtcgc tcctggacat ttacgattcg
    18781 actttaccca ctttggtcaa atcacttcag atgaattagc tgaaatggaa agaatcgtca
    18841 acgaaaaaat ctgggaagct atcccagttg aaacaattga aacagatatc gatacagcca
    18901 aaaacatggg tgcaatggct ttgtttggtg aaaaatacgg acatgacgtt cgagtagtaa
    18961 atattggcgg ctggtcaatc gaactgtgcg gaggcacaca tgtagcaaat acagaaaaca
    19021 tcggaatctt caaaatcgtt tctgaatcag gaattggtgc aggcgtgcga cgaatcgagg
    19081 ctgtaacaag taaagaagcg tacgaactac ttgaagaaga agaaaaacaa ctaaaacaag
    19141 tagcaacaat tgttaaatca cctcaattga aagaagttgt ttcaaaagcg gaacaattgc
    19201 aacagcaagt aagagagcta caaaaggaaa atgaacaatt agctagcaag ttagcgaatc
    19261 aacaagctgg tgatgtattc aaagatccag aaacgatcaa tggaaaaaca atcattgcag
    19321 cacaagtaaa agtgaaagat atgaatcagc tgcgtcaatt agctgaccaa tggaaacaaa
    19381 aaaatatttc agatattctt gttttagcaa acgaacaaga aggaaaagtc agtctgctag
    19441 cggcaatgac gaaagaatca aatgaagctg gactaaaagc tggcgacttg attaaagcaa
    19501 tcgcaccgaa agtaggcggt ggcggtggtg gacgtccaga catggcacaa gctggcggga
    19561 aaaatcctgc tggtattcca gatgcactta aagctgcgaa agaatgggtt gcgcaacaat
    19621 agggcgttta cgtttgacag aaaaacaaaa gttcaaacat tgaacgaaac atgattatgg
    19681 gggcgaagac aaacaagtct tgccctcata cttttttcaa ttggatggcg catctaatca
    19741 aatggtcgga ttcggatggt ctttagttga cgaaagtgac agaaattttt acgattagta
    19801 taaataaaaa ggggtgaaaa aatgaatagt agaaataaga cctttcgact agtcttacgt
    19861 gcgatcttgt tagcaatcat catcgtacaa gcgatggttc cttggctggg gtttattcca
    19921 ttaggattca ttagtttaac aattatccat atcacagtaa ttattgctgc agtagtatta
    19981 ggcccaaaag atggcatggt gattggcttg ttttggggaa tcgctacaat tgttcgtgcc
    20041 tatgccatgc caacaacgcc atttgataca ttagtgttca cgaatccgat tatctcggta
    20101 gttcccagag tacttgttgg cttagtagca ggcttggttt tccactggat ttatcaaaaa
    20161 aataaatcaa taacgatcag ctcagccttt gcaggggtac tgggttcatt ggtcaataca
    20221 gtcttagtgt taggattcat gggattattt tatacaggtg caacggcaga tgcctatggt
    20281 gtagactctg ctcttttatt taaaacctta gcaggggttg cagcaatcaa tgggatacca
    20341 gaagcaatag gtgcgggaat cataacacca ttactagcaa aagcgttatt tgcagcaaca
    20401 ccgttgaaac cagaataatg accatctttt aatagtaata ggacgcacga tagatagaaa
    20461 aaggaagaga ggagaggaaa acaatcgtcc tctccatctt tttacctgag caacaagcaa
    20521 actagaaggg gtaaaaaact tggctaagaa acaagaagaa aaaaagaaac aaataccgca
    20581 acagcggaca aaaaaaggag tactagcggg tatcttagga ttggttacga atctgatctt
    20641 gtttgtctct aagctaatga tcgggctttt ttcaggaagt gtctccatta tggctgatgc
    20701 agtgaacagt ctatcagata ctgcttcatc catattgact ttgatcggat ttaaaattgc
    20761 tgcaaagcca gcagatcagg aacatcctta tggacacgaa cgcttcgaat atatcagtgg
    20821 gttatttgtt tcgatcatca ttacttatgt aggatttcaa tttttagagt cttctgctga
    20881 aaaaatcatc catccagaaa atgtctcttt aacacccatc gtcttttttg tcctaatcat
    20941 ttccatcttt ttgaaatttg cacaaggcaa aatgtatcag gttattgcgc aatccattga
    21001 ttctgaaaca ttgagagcta cagcaacaga tagttataat gatgtcttta ctacactggc
    21061 tgtattgctt tcagcagcaa tcgaatgggt aactggatgg cgtattgatg gatatatagg
    21121 ttttgcttta gcattatata tcctttatag tggattgacg atgcttcgaa attttgtata
    21181 cgaactatta ggaagtcgcc caacgccagc agagattgaa gaaatggaag agcatttaaa
    21241 tgcttgcgat gatatacttg gctatcatga tttattggtg cataactatg gacccaataa
    21301 acgctttgca tcagtccaca tcgaagtaga tgaatcaatg aatttgaatg tggctcataa
    21361 gattattgat ctgatagaaa aagactttaa aaagtctttg gatgtggaac ttgtctgtca
    21421 cttggatcca atgcctgttg ataacgaaaa atactataat atcttgcggc agttaaagca
    21481 aattcttctt gaaacaggta cagggcttaa tattcatgat tttagagtaa ttcatcaagg
    21541 aaaaacgctg caatttgatg tagtggtccc tgagaaattc cagtttgttg atacagaact
    21601 agaaagaatc ttacgtagtc aaatagaaga aaaaatcgga gattaccaat tggaaattac
    21661 gtttgatcac aattatcttt tatattaaat gagaaactat aaaaagactc cttaaagttt
    21721 ttaatttaaa gagtcttttt ttcttttaat tgtttatgga gagcctgacg tgcaagatta
    21781 tctgctcctt tatttttgtt ttcgggcaac cattgcagga tcaataaaga aaattcggat
    21841 agaagttctt ggattctttg aaggtaggga aggaagagct cgttcttcgt tgcgtttttg
    21901 tcgaccgtag aaactagtgt tttgctgtct gaaaaacaga aaatcgtttc attctgtaag
    21961 tcgtttttct ttagaaattc taaagttttt aaaaagactt cgaactctgc ttgatggttt
    22021 gtccctatag aaagcgggat agatagctgt tcttgtttac cttgatagac aatcaagatt
    22081 ccacctccac taggaccagg gttgcctttt gtagaggcat caatgtatac ttttaacata
    22141 aaaagagatt ctcctttttg ttcaaactaa tgttatggta agattatatc attactgaat
    22201 cggtgagagg ttagagaatg aaaaaaaata ttcgatggca gcctgaactg gcacatacga
    22261 tcatctattg gtcattgacc ttgatcattc tgttttttag tctgattctt tctttagaaa
    22321 acacaggtcc ttattggaaa agcaattttg ttttaggtat ttttcttgtt tttctatttc
    22381 taggtttgcg gcgttctttt attttaaaat caaactctgt gattatacgt tatgctgctt
    22441 tttggaaaga ccgagaaata tctgtcggac agattcgatc tttgacgcca actaatactg
    22501 gggtgcaaat gatgttgcaa gatgagaaag ccccatctgt tttcatgatg cgaaaaaaag
    22561 atcaagtagt cctttttgat cattttgaaa aaaacggacc caaatcagaa tcaattcctt
    22621 atccttatac gaaaaaaaga aaaagctaat tttaaaaatc agaacctaaa aaaacgaatt
    22681 tttacaggaa aagaaaagag tgagacgtac ggttcatccc gtttagcgtc tcactctatt
    22741 tgtttatcta ttcatgcata ctagtatcgg tagtctgaac gttgcctttc ttgacatggg
    22801 cagcttgtgt tcctcgattc ccttcgatga tctcaaattc gaccacttga ttttcttcca
    22861 aagttttgaa tccctcttct tcaatcgcag taaaatgtac aaaaatttct tctgtgtcat
    22921 cataactgat aaagccgtat ccttttttgt tgtcaaacca ttttacaatt cctgtggtca
    22981 aagcactcac gacctttcta aagtctgatc atagccttca ttataaagag tatttataag
    23041 tacgtcaaat aaattaaaaa cctgtaattt tatgtttttt ttctgaataa aaaaaggtat
    23101 aattggcata tcttaacaaa gaagatattt tgttgaataa agttcgtgaa aaggggtaat
    23161 caaatgaaga atgatctgca aatttcacaa gaaacagagc tagaaccgat tgttgaagtg
    23221 gctagtaaat tagatcttaa ggaagacgat ttggaactgt atgggaaata taaggcgaaa
    23281 atcaattttt ctggaatcaa tcgatcaaag gataacgctg aggggcattt gatcttagtt
    23341 acttccatca atccaacacc agctggcgaa ggaaagtcaa cgatcactgt agggttagga
    23401 gacgcgctca ataaaatcaa taaaaaatct gttattgcat tgcgagaacc ctcacttggt
    23461 cctgtgatgg gaatcaaagg tggtgctgca ggcggaggat atgcacaggt attgcctatg
    23521 gaagatatca acttgcattt tactggtgac atgcatgcta tcacaacagc taataatgca
    23581 ttatctgctc ttttagataa tcatattcat caaggaaatg aattgaacat cgatgcccgc
    23641 cgagtgattt ggaaacgggt agtcgatctc aatgatcgtg aactgcgtaa agtaattgtt
    23701 ggcttgggtg ggccaatcca aggtgttcca agagaagatg ggtttgatat cacagttgcc
    23761 agcgaaatca tggctatctt gtgtcttgcg gcagaccttg aagatttaaa ggctcgtctt
    23821 gcaaggatcg ttgtcggcta tacatttgac cgtcagcctg tgactgctgg agacttgaaa
    23881 gcagaaggcg ctctggcatt actgctgaaa gatgcaatca agccgaatct tgtacaaaca
    23941 atttacggaa caccagcttt tgtccacggg ggaccgtttg ccaatatcgc tcatggctgc
    24001 aatagtattt tagctaccaa gacagcattg agattagcag attacgttgt cacagaggca
    24061 ggatttggtg cagatcttgg cggagagaaa tttttagata tcaaagtacc taacttgaaa
    24121 aaagcgccgg atgctgtggt gattgtcgcc actgtccgtg cattgaaaat gcatggcgga
    24181 atgaaaaaag atgaacttaa aaatgagaat cttgatgctt tgaaagtagg ttttgcaaat
    24241 ttaaagcgcc atatacgtaa tatggaacaa tatcagctac ctgtgatcgt cgcaatcaat
    24301 gaattcgtaa cagatacaga caatgaactc acactgttgg agcacttgtg tgaaaatcag
    24361 gggattcttg ccaagagagc gagtgtatgg gcagatggag cagaaggcgg cgttgattta
    24421 gcaaaagctg tagtacgatt gattgataga aaagaagcta attacaagcc attataccgc
    24481 ctagaagaaa cgatacaaga aaagacagaa acaatcgtca agaaaattta cggaggaaat
    24541 ggtgttgttt tcagcaaaaa agcgcaaaaa caaatagaag agtttacgaa gaatggatgg
    24601 gacaaactgc cgatttgtat ggcaaaaaca cagtattcat tttctgatga tccttcactg
    24661 ctaggtgcac cggaagattt caccatcacg atccgcgaaa tcatcccaaa attaggggca
    24721 ggatttttag tagccttgac tggagatgtt atgacgatgc ctggtttgcc taaaaaacct
    24781 gctgcattga atatggacgt gacaaatgac ggagaagtgt tgggattgtt ttaagcttga
    24841 ttataatcta ccatcgaagg agctgtattt tgactacagc ttcttttttt agacgatagg
    24901 gaattaattt tgtttacact aggatcattc tttttcttta ttgtattttg agctatacta
    24961 aagcataata ggagggtatg atgaaaacga catttataag aaaaaccggt ttttacggta
    25021 tgggtagctc gattcagcta agaatcaaca atgaaaaacg cagtgttctc agtcatgaac
    25081 aaaagataac gcttgatctg gaagtgccct ttacgatgca ggtcaccttt tattggctaa
    25141 aaagccccgt ttatacagtg aaagaagcaa agcctgctta tgtgatcaca atgaattact
    25201 tgattcttca aatctatccg tttttatttc tagcaactgg gttgggggcc gttttcctac
    25261 aaaatttatt tttcagtttt tttgcagtta ttgtgttgat tgcgttcttt ttctatataa
    25321 aaaaccgggc atatttgatc aaggaggaaa attatggcaa actctgatct ttttttaatc
    25381 agtttcaatc gaatcgaaaa atggatgaga gacgagatgg gaaatgcacg aaatatggga
    25441 tttaccgaac ttgtcagacg cctagctcaa agaaaacaat taatgatcag aaaatacgaa
    25501 gatgatcttt tacagcttgc tcagttaagg aatgcgatcg tccatgatcg gatcgcagtc
    25561 gattttgtca ttgcagagcc aaatgattgg acagtcaagc gaatccagct gatcgaacaa
    25621 gaactgattc agcctgaaac cgtgctgcct cgatttgcaa aacgtgtaac aggttttgaa
    25681 caagatcttc cgttacttga actgttaaag atagtagcag aaaaaaggta ttcacaattt
    25741 ccgttataca ataaaggaaa atttgtagca ttgattactt tacgtaatat cgggttttgg
    25801 ctagcaaaag aaagccaaaa aggtccggtt gatttaacaa ataaacgagc gttggatttg
    25861 atcatccaaa acggaaagta cacaaattat cattttgttc cagctaaaac acatatttac
    25921 gaggttgaag cgatgtttcg tgagcaaggg actttggaag ccgtacttat cactaaagat
    25981 gggaatcccg atggtaatct gctcgggatc gtacgacctc gtgatattta taaacaaata
    26041 gaaaaggatt gattttttgt taattattta ttggatattc agcgctttgc tagtaggagt
    26101 ggatcagttg gtcaaatggt ggatcactga taatctagcg cttggagaga cgaaaaatct
    26161 tataccaggt attttgtcac tgaatcatat tcgaaacact ggagccgcat ggagtatgct
    26221 agaagggaag atgtggttct ttactatagt gacactcatt gcagtcgttg tgattctcac
    26281 attgatgatt aaaaatcgtg aaaaaggtaa tcgctggttc atgattggat tgagtttgat
    26341 tctagctggt gcgattggca attttatcga ccgtattcgt cttggctatg tagtagatat
    26401 gttccagaca gattttatga gctttccgat ttttaacgta gcagatgtga cacttgtatg
    26461 tggagtgatt tgtatgttaa tttatattat tttagatgaa aaggatcaaa gaaaaaaatg
    26521 acagaactta aaacgacgat tcaccatgaa tctggtagga tcgataaagt attgactaat
    26581 ttattcaccg attacagtcg ttcgcaaatt cagctgtggc tgaaaaatgg agcggtttct
    26641 gtcaatggac agccagtcaa agcaaattac aaagtaaaac aaggagacga gattactgtc
    26701 ttgatccccg aaccagaaac attagatgtg gtcccagaaa atatcccgtt gacgatcgtt
    26761 tacgaagatg aagatgtagc ggtgataaac aaacctcaag gaatggtcgt tcatccttca
    26821 gcaggtcata cgcatggcac aatggtcaat gcgctgatgt accatatcaa ggatctttct
    26881 acgatcaacg gcgttattcg tccaggtatt gttcaccgaa tcgacaaaga tacttccgga
    26941 ctgctaatgg ttgccaaaaa tgaccaggca cacgaatcat tagctcagca attaaaagat
    27001 aagacctctt tgcgcaaata tgttgcttta gtccatggag agattcctca cgaaaaagga
    27061 accatcaatg cgccaatcgg ccgttcgaag gaaaaccgga aaatgcaggc gataagagaa
    27121 gatgggaagt cggctgtcac acattttact gtattggaac gtttcgaagg atttactctg
    27181 gttgaattaa aactagaaac cggaagaaca caccagatcc gtgtgcatat gaagtatatc
    27241 ggttatccgt tagctggaga tccagtatac ggaccgaaga aaactttgaa aggcaatggt
    27301 cagtttctcc atgcgcaaat gttaggtttt acgcacccga ctacaaacga aaagatgatc
    27361 tttgaagcac ctcttccaga agtttttgaa aaaactttag aaaaattaag aaaaaacatt
    27421 gcattttaat ttagataacg gtatagtaat taacaacgaa agcataaaac ttaatagaat
    27481 tcctttaagt ttagtcccgt gaggctaaga agggtgggag caaggatacg tatggtgcgc
    27541 cataagtaga ttgctcattg acatagtata gctatcagtg tatcagtata cgctcagtct
    27601 aaacattcct cctgtcctct tagggcagga gtttttttat gcaaaaaagt agggggaatg
    27661 aaaatgcaag caaaagaagt agtagatcag gtaaccatga agcgagcatt gactcgaatt
    27721 acttatgaga ttatcgagag aaaccatagt atccaagata tcgtattggt aggtatcaaa
    27781 acacgaggaa tctacattgc atcaagaatt gccgaacgcc tgaagcagct agaagatatc
    27841 gatattcctg taggagaact ggatatcact ttataccgag atgacaaaaa agaaaatcca
    27901 gaagaaccgg aacttcattc ttctgacatc ccagtttcct tagaaggaaa agaagttatt
    27961 ttgattgatg atgttttgta tacaggacga acgattcgag cagcaatgga cgcagtaatg
    28021 gattttggca gaccaagaaa aatttcatta gcagtcctgg tcgatcgtgg gcatcgagaa
    28081 ttgccaatcc gtgcagatta tgttgggaag aacattccaa catctcgggc ggaagagatt
    28141 ttagtagaga tgcaagagct tgatggacaa gatcgcatca tgattttgaa agaggaagat
    28201 tagaggagag agaaacatgt cggagaaaaa aggatttcat aatgatgacg tggtgttaga
    28261 tatccacgat cgcccaaccc caggacattg ggtaggatta agtttacaac acttgttcac
    28321 gatgttcgga gcaaccgtgt tagtccccat cttagtaggt atcgatccag gtattgcgct
    28381 agtcagttca ggactaggta cattggtgta cttatttact actaaaggaa agatacctgc
    28441 gtacttagga agcagcttcg ctttcattgc agcgatgcag cttttgatga aaacagatgg
    28501 ttatccagcg attgcacaag gagcagtcac aactggatta gtctatttga ttgttgcgct
    28561 gatcatcaaa aagatcggtt cagcatggct ggataaaatc ttgcctccaa tcgtcgtcgg
    28621 tccagtcatc atggttatcg ggttgggact tgcggcaaat gcagcaacaa atgctatgta
    28681 taatcagggc acgtatgatt tcaagtatat tgctgtagcg ctgatcacat taggattaac
    28741 aattttcttc aacatgtggc taagaggttt tctcggattg attccgattt tactaggtat
    28801 tattagcgga tacatcgtag ccttgctgtt tggaatcgtg gatactaagc caatcgtaga
    28861 cgctgcctgg tttgctgttc ctaactttga gattcccttt gtacaatatg aaccaaagct
    28921 atatcttgga gcaatcacaa caatggcacc catcgctttt gtgacgatga cagagcatat
    28981 cggccatctt atggtattga ataaactaac taaacgtaat ttctttgaag aaccgggtct
    29041 tcataagacg ttgacaggtg atggattagc acaaatcgtg gcagcctttg tcggaggtcc
    29101 tcctgtaaca agttacggtg aaaacattgg tgttctggct atcacacgtg tccatagcgt
    29161 gtttgtgatc ggtggagctg cagtatttgc agtcatttta ggattcgtag gaaaattaag
    29221 cgctttgatt ttaagtatcc ctggaccagt catctcagga atcagtttta tcttatttgg
    29281 agtaattgcc gcaagtggaa tgaagatttt aatcgagaac aaaatcgatt ttgataaaaa
    29341 gaaaaatctg ttgattgctt cagttatctt agtagtagga attggcggac tcgtctttga
    29401 agtaggcaca tttacattgt cggcaatggc attagcaact gtacttggca tcattttaaa
    29461 tcttatctta ccagaaactt cacgaagcga agaaaactaa ggaggaaaca ttatgatcat
    29521 caaatcagaa cgtatcagct taaagcattt attgaccgtt gaggcactta ctgatcaaga
    29581 agttatgggc ttgatccgca gagggcagga attcaagcaa ggtgctaatt ggactccgca
    29641 aaagcgccag tactttgcta caaacctctt tttcgaaaat agtactcgca cacataaaag
    29701 cttcgatgta gcggagaaaa aactagggct agaagtgatt gaatttgaag caagcacaag
    29761 ctctgtccaa aaaggggaaa cactatacga tacagtactg acgatgtcag cattaggcgt
    29821 agacgtagcg gttatccgtc atggtgatga gaactattat gacgaactga tacaaagtaa
    29881 aacaatccag tgttcgatta tcaatggagg agacggaagc ggacagcatc caacccaatg
    29941 cttgcttgat ttgatgacca tttatgaaga atttggtcat tttgaaggtc tgaaagttgc
    30001 catcgtaggt gatatcactc actctcgcgt agctaaatcc aatatgcaga tgttaaaacg
    30061 tctaggcgca caagtattct tctcaggtcc tagagaatgg tacgacgatg aattcgaagt
    30121 gtacggacat tatatgccat tggatgaact actagatcaa gttgatgtca tgatgatgct
    30181 tcgggtgcaa cacgaacgcc atgatggaaa agaaagtttc tcaaaagaag gctaccatca
    30241 ggaacatggg ttaacagttg agcgtgcgaa gaagttgcaa aaacatgcaa tcattatgca
    30301 cccagcacca gttaaccgtg atgtagaatt agctgattca ttagtggaag gattacagtc
    30361 gcggatcgtt cagcaaatga gcaatggagt attcgtcaga atggcaatct tagaagcagt
    30421 gctaaatgga aaagcgtaat tataggagga tgaaaaaatg aaaacactca ttaaaaacgg
    30481 tcagatcaat acacgaaaaa atatgacgac accagcagaa atttggatag aagatgggcg
    30541 aatcaaagca atcggtacag gattctcaga agccgaattt gatgaagtgt ttgatgcaaa
    30601 gggacaattg atcacacctg gtttagtgga cgtccatgtt catttgagag agccaggatt
    30661 tacatacaag gagacgatcg aagctgggac tcgctcagct gctcgtggcg gtttcactac
    30721 tgtatgcgcg atgccgaatt taaatcctgt acctgatacg gcagaaaagc tgagacaagt
    30781 atatgacatc attagaaaag atgcagttgt gaaggtattg cagtatgcgc caatcacaga
    30841 aaatctgcga agtgagaaat tagttgatca agaagcactg attgaagaag gtgcttttgc
    30901 tttcacaaat gacggtgtag gtgtccaaac agctgggacg atgtatctgg ctatgaaaga
    30961 agctgcaaaa aacaataaag ccctagtagc ccatacagaa gatgaatctt tattatttgg
    31021 cggcgttatg cacgctggca agaaggcaga agaacttggt cttcccggga tcttaagcgt
    31081 aaccgagtct tctcaaattg ctagagatct gttgctagct gaagcaactg gtgttcatta
    31141 ccatgtttgc catgtttcta ctaaagaaag tgtccgtgta atcagagacg caaaaaaagc
    31201 aggaatccac gtaacagcag aagtttcacc ccatcatctt attttgatcg acgaagatat
    31261 tcccgaagat ttcggctttt ggaaaatgaa cccgccgcta agaggacggg aggacagaga
    31321 agctttgatc gaaggcttgc ttgacggtac gatcgattgc atcgctacag accatgcccc
    31381 ccatggatta gaagaaaaaa gccaaagttt catgaaatca ccatttggta tcgtaggaag
    31441 cgaaacagcg tttcaactga tctatactca ttttgtagaa actggtcgat tcacgttgga
    31501 acaagtgatc aattggttgg cagttaaacc ggctgagatt tttggtttga atgcaggaac
    31561 gctaacggtt ggtgcccccg ctgatgtagc agtttttgat attacacaaa cttgcacgat
    31621 cgataaagaa gactttttat caaaagggga gaatacacct tttatcggct ggaaagtaaa
    31681 aggcgaaaca caaatgactt ttgtcaacgg aaaacttgtg tggcagaagg gagaataaaa
    31741 gtatggaacg tttgcttata ttagaagatg gaacagtttt cgaaggaaag gcttttggtg
    31801 cagatgctag tgtcttcgga gaaatcgttt ttacaacaag tatgactggt tatcaagaaa
    31861 ctatcactga tcaaagtttt aacggtcaaa tcattacatt tacctatcct atggtgggta
    31921 attatggggt aaatagagat gattatgaat cgatttctcc aacatgcaaa ggagtagtag
    31981 taaaagaaca tgcacgtgta gcttcaaact ggcgaaacca aatgacgcta gattcatttt
    32041 tgaaacaaaa aggaattcct ggaatatcag gtatcgatac gcgcgccctt actcgcaaaa
    32101 tccgtgaagt cggaacgatg aaagctagta tagttgatgc tggagattcc ttcgaacatg
    32161 catttgatca gctgaaagca accgttctag caaccaatca agtgcagcaa gtctcaacta
    32221 acaaacctta tccaagtcca ggaacaggtc ggaaagtcat tgtcattgac ttcggcttga
    32281 aacatagtat tttacgagaa ttgagtaaaa gaaactgtaa cctcacagta cttccctata
    32341 acacagatgc cgagacgatt ttagcgctat caccagacgg agtcatgctg acgaatggac
    32401 ctggtgatcc aaaagatgtg ccagaagcaa tcgaaatgat caaaaaaatc caaggaaaag
    32461 taccgatttt tggtatttgt ctcggtcacc agttatttgc tttagccaac ggtgcagata
    32521 cctataaaat gaaattcgga catcgaggat taaatcaccc ggtacgagaa gtagcgaccg
    32581 gaagaattga ttttacttct caaaatcatg gctatgcagt cgatgaagcc acgattgatc
    32641 cagaaaaact catcgtaact catgtagaag taaatgacgg aacagtagaa ggagtcaaac
    32701 acagagatta tcccgctttc agtgtgcagt ttcatccaga tgctgcccct ggtccgcatg
    32761 atgcactaca tttatttgat gaatttatgg aaatgatgga cgcaggaaag gagcagtaaa
    32821 cagatgccga aacgtacaga tatcaagaaa attatggtga ttggatctgg tccgatcatc
    32881 attggtcaag ccgcagaatt tgactacgca ggaacacaag cctgccttgc cttaaaagaa
    32941 gaaggatatg aagtggtttt agtaaattct aatcctgcga cgatcatgac ggataaagaa
    33001 gtggcagatc aagtatatat cgaaccgatc acacttgaat ttgtatcaag gattcttcga
    33061 aaagagcgtc cagatgctct ccttccaact ttaggcggac agacaggcct caatatggca
    33121 atggagctgg cagcatcagg tattttagaa gaattgaaca tagaacttct aggaacaaag
    33181 ctttctgcga tcgatcaagc agaagatcgt gatctattca aacagttgat gaaagaattg
    33241 aatcagccaa tccccgagtc tgaaatcgtc aatacagtag aagaagctgt agattttgca
    33301 aataaaatcg gctatcctgt catcgttcgt ccagccttta ctttaggcgg aactggtgga
    33361 ggtatgtgtg aaaatgaaga agaattacgt atcgtatcag aaaatggatt aagtctttcc
    33421 cccgctaccc aatgtttgat tgaacgaagt attgcaggtt ttaaagaaat tgaatatgaa
    33481 gtgatgagag attcggctga taatgcaatc gttgtctgca atatggaaaa ttttgacccg
    33541 gtgggtatcc atacaggtga ttctatcgta tttgccccta gtcaaacatt gtctgaccat
    33601 gaatatcaaa tgcttcgtga tgcttctctt tcgattattc gagcacttaa gatcgaggga
    33661 ggctgtaatg tccaactcgc tcttgatcca catagtttta attattatgt gattgaagtc
    33721 aatccgcgtg tttctcgttc atctgcgtta gcaagtaagg cgactggcta tccgatcgct
    33781 aagctagctg ctaaaatagc gcttggatta acattagacg aaatgaaaaa tcctgttaca
    33841 ggaacgactt ttgcagaatt tgaacctgca ttagattatg ttgtagctaa aattcctcgc
    33901 tggccgtttg ataagtttga aaacggagaa cggcttttag gcacgcagat gaaagcaact
    33961 ggtgaagtga tggctatcgg tcggaatatc gaagagtctt tattgaaagc tgtgcgttct
    34021 ttagaaatcg gtacacacca tatcgaactt cctgagttgg cagacatcac ggacgatgac
    34081 ctaatccaaa aagtggttcg agcacaagat gatcgcctgt tttatgtagc tgaagctatt
    34141 agaagagggt acaccataga agaattagcg gatttgacaa aaatcgattt attcttttta
    34201 gataaactgt tgcatatcgt agaaatcgaa cagcagttga aacagcagcc gttggatgac
    34261 aagatattga aaacagcgaa acaaaacggt tttacagaca aaaaagtggc ggagctgtgg
    34321 gaaataaacg aagaagccgt tcgccagatg agaaaagaaa atgatttgat tcctgtatat
    34381 aagatggttg acacttgtgc agcggaattc gaatcaaaaa caccttattt ttatagttcc
    34441 tatgaatatg aaaatgaaag ttcacgatca gaaaagccct caattctagt actgggatct
    34501 ggtcctatcc gtatcggaca aggggttgaa tttgactatg cgactgtgca ttctgtcaaa
    34561 gcaatccagc aggcaggata cgaagcaatc atcatgaaca gcaatcctga aacagtttcg
    34621 actgactttt ctatttcgga taaattatat tttgagccat tgaccttcga agatgtgatg
    34681 aatgtgatcg agctagaaca gccgatagga gtaatcgttc aatttggtgg tcagacagca
    34741 atcaacttag ccgaaccttt gactgctgct ggtgtaaaaa tcttagggac aacgatcgaa
    34801 gacttggatc gtgcggaaaa tcgtgattta ttcgagcaag cgctgaaaga gttggatatt
    34861 cctcaacctt taggggatac tgctacaagt aaagaagaag ccgtggttat cgcttcgaga
    34921 attggttatc cagttcttgt tcgtccaagc tatgtattag gcggacgtgc gatggaaatc
    34981 gttgaaaacc agcgagattt agaagattac atggaacatg ctgtgaaagc atctccagaa
    35041 catccagtac tagtggaccg ttacttgctt ggtggtgaat gcgaagtgga tgcgatttgt
    35101 gacggtgaaa cagtactcat cccagggatc atggagcata ttgagcgtgc tggtgtccat
    35161 tcaggggatt caatggctgt gtatccacct caaacattat ctgaatcgat caagaaaacg
    35221 atcgaagatt acacgatccg cttagcatta ggtttgaatt gtgtcgggat gatgaatatc
    35281 cagtttgtca tccatgaaaa tgaggtttat gtgatcgaag tcaatcctcg agcaagtcgg
    35341 actgttccat tcttaagtaa ggtgacagga attccaatgg cacaaattgc gacgaaagct
    35401 attttgggag agaaactaaa gacacttggt tatgaaaacg gactttatcc agaaacaaaa
    35461 gaagttcatg ttaaagcacc tgtcttttct tttacgaaat tgcagaaagt tgatacttac
    35521 ttagggcctg aaatgaaatc gactggagaa gtaatgggat ctgacagaca attagacaaa
    35581 gctttgtaca aggcattcga agcttctgga ttacacttgc ctgaatatgg agccgtatta
    35641 tttacgattg cggacgaaac aaaagaagaa gcactagaat tagctaaacg ttttacagaa
    35701 attggctata gtctgatagg aacgaaacat acagctgctt atttcgaaaa aaatggtctg
    35761 gtcgttgaaa cagtagcgaa aatttctgag gaagcagcag aaaaaaatgt agtcgactta
    35821 ataagagatg gtaaaacaca agtggttgtc aatacgattg ataaagatcg gggaaatgct
    35881 tctaaagacg gtttcatcat ccgaagagaa gcagttgaac atggtattcc attgtttact
    35941 tctttagaca cagcagatgc gatcgttcga gtgatggaat cccgtgcttt ttcaactaac
    36001 cctatttaac ggcgagcaca tgttaagaca aaaagacgaa aaaccgttgc aggaggggac
    36061 agatgaaaca agaaatgatg gaaatcgttc agcaaaaaca gctggcacca aagatttttg
    36121 aaatgacatt gaaaggtgat ctagtaaaag aaatgcagca accaggacag ttcttgcata
    36181 ttctcgtgcc gcgtgcagac ttgctattac gccgaccgat tagcttgaat catatcgacc
    36241 acgaaacaaa tacttgccgt atcatttatc gggtggaagg tgaggggact agagtcttct
    36301 ctactctttc tgccggagac catttagatg tcatgggtcc tttaggcaat ggttttgatt
    36361 tgtccaatct tcatacagga gacgaagtat ttataatcgg tggaggaatc ggtgtccctc
    36421 ctctatatga gttatcaaaa cagttagtcg aaaaaggaat taagccaacg cattttttag
    36481 gttttgccac acatgaagtc gtttattatg aaaaagaatt taatcgtcta ggagaaacaa
    36541 gaatcgctac tgacgatgga acatacggta tgcacggaaa tgtcggtaat ttattgttag
    36601 gaacgaagac ggaacctaca gctgtttttg catgtggttc aaacgggtta ttgaagacag
    36661 tggaacagct gttttcttcg catcaaaatg tccagttatc attagaatcc cgcatggcat
    36721 gtgggatagg ggcttgctat gcttgcgttt gtcatacgcc ggaagatgaa acaggaacaa
    36781 aaagtgtgaa agtttgtgac gaaggaccga tttttaaaat aggagaggta attatatgaa
    36841 tgagaatcct ttagcggtca aacttcctgg cctagaatta aaaaatccta tcatgccggc
    36901 aagcggctgt ttcggttttg gcaaagaata cggaaaatac tatgatttga atcagcttgg
    36961 atcgatcatg gtcaaggcaa cgactccaaa tgcccgcttt ggcaatccca cgccaagagt
    37021 ggcggaaaca ccatctggca tgttgaatgc aattggtttg caaaatcctg gtctagacgt
    37081 tgttatgcat aaacttcttc cagaattaga ggagtacaat gagttaccca tcatcgcaaa
    37141 tgttgctggt gcttgtgaag aagactatgt agaagtttgt agcaaaattg gcgaagcacc
    37201 aaatgtgaaa gcaatcgagc tgaacatttc ttgcccaaat gtcaaacatg gcggaattgc
    37261 ttttggaaca gattctgatg ttgcttttca attaacacaa gcagtaaaga aagtttcttc
    37321 tgttcctgtc tatgtcaaat tgtccccaaa tgtaacagac atcgttccaa tcgctcaggc
    37381 aatcgaagct ggaggggcag atgggtttac gatgatcaat actcttcttg gtatgcggat
    37441 tgaccttaag acaagaaaac cgattttagc caatcaaaca ggtggactct ccggaccagc
    37501 aatcaagcct gtcgctattc gtttgattca ccaagtagca agtatatcca gccttccaat
    37561 cattgggatg ggcggcgtgc agacagtgga tgatgttctt gagatgttta tggctggagc
    37621 aagtgctgta gctataggga ccgcgaattt caccgatccg tatatctgtc ctaaactaat
    37681 taaagagctc cctgtgcgaa tgagcgaact aggcatcgaa tcgctggaaa gattaatcaa
    37741 agaagtgaga gaggaacgtg aacgatgaat caactagacc aacgaccaat tattgcatta
    37801 gatttttcaa ctaggcaaga ggtagaagac tttcttcgat ttttcccgaa agaagaaaaa
    37861 ttgtttgtga aaatcggaat ggaattgttc taccaagaag gacctgaaat cgtacgttat
    37921 ctaaaagagg ctggtcataa tgtattttta gatctgaaac ttcacgatat tccgaatacg
    37981 gtcgaaaaag caatgcgggg attggcaaag cttggtgttg atctcacctg tgttcatgcc
    38041 gctggcggta ttcgtatgat ggaggcggca atgcgaggat tagaagaggg gactccagaa
    38101 ggtggaaaac gtccgctact tctagctatc actcagctta cttctacaag tgaagaagaa
    38161 atgcatgccg atcaactaat cgaagtttct ttagaaaaaa gtgtgatcca ttatgctagc
    38221 tgtgccaaaa aagcaggatt agatggtgtg gtttcttctg cttgggaagt agaagcgatc
    38281 aaagaaatgg caggagacga atttgtttgc ttaactccgg gtataagacc agaaggaaca
    38341 gtcgcaggag atcagacaag agtagtcaca ccttctcagg caaaaaagat cggctcaact
    38401 tttatcgtta taggtcgacc aatcactcag tcaactaatc cttataaagc atatcaaacg
    38461 attcaaacag aatggagcta acctaaaatg aatgttgaac aaagtatcgc aaaagactta
    38521 ttagaaattg aagcagtatt tttaaatcca agtaatcctt ttacatgggc aagtggaatc
    38581 aaaagcccaa tttactgtga taaccgaatc acgatgagct atccaaaagt ccgaaaagag
    38641 atcgcaaaag gattagcaag caaaatcaaa gaagcttacc ctgaagtaca agtgattgct
    38701 ggaactgcaa cagcaggaat ccctcatgcc gcatgggtag cggaaatact ggatttgcca
    38761 atggtctata ttcgaagtaa ggcgaaagat catgggaaag gtaaccaaat cgaaggacgt
    38821 atatttgaag gtcagaagat ggttgtgatc gaggatttga tttctacagg cggaagtgtc
    38881 ttggaagcag ctgaagcagc aaaaagagaa ggtgcggata tccttggtgt tgcggctatc
    38941 tttacgtatg agttgccaaa aggaaaagca aatttcgaaa aagccgaaat ccctcttatg
    39001 acgttgacca attattctgt attgattgaa gcagctttag aagatcgtta tatcgatgag
    39061 caagaattaa ctctgctaaa agaatggaaa aaagatcctg aaaattggca gatttaagcg
    39121 cgcttgatga agatagagaa atccgatttg tgtctccaga atcatcaatt ggaatagcaa
    39181 aaatccaaaa actgattgcg agaagcatct tttcatcagg tatgaaaaga aacttctatc
    39241 gtgatcagtt tttgattttt ttaaaattca tttttctaag actggttagc agaaagaaga
    39301 gaataatctc ttctcttttt tctattatat atagattttc tctatttttt ggtaagggag
    39361 ctgtttcaaa aatggtaaag agcggaaatg ttgcgaatat cagttattta atgatatgat
    39421 attcggaaaa agaaatctca aagggaggta acttttatgg ggttgaatga atttatttta
    39481 ggattgaaca atttagagac gatcacaagg gcacctggat tttttaaata tacagagcat
    39541 acagttgcag cacattcgta tcgtgtagca tctattgcgc aagttctagg agacattgaa
    39601 gaagcgaatg gacaaccgat cgattggaaa ctgctctatg aaaaatcatt gaatcatgac
    39661 tacacagagc gttttattgg tgatatcaaa acgccggtga aatacgcaag caaagagtta
    39721 agagggatgc tgcaaacagt tgaagaaaag atgacggacg aattcatcaa ccaagagatt
    39781 ccagctgagt tccaagaagt ttatcgccgt cggttgttcg aaggaaaaga tgaaaccgta
    39841 gaaggagaac tattagccat ttcagataag gttgaccttc tttatgaatc ttttgatgaa
    39901 atcatcaaaa ataacccgga aaaagtttat aaggagatgt tcattgaggc agtgactacg
    39961 attaaaagct ttgaacatcg gccttctgtt cagtatttct ttaaagagat atttccggaa
    40021 ctattgaacc aggaatttta tggaaaagag gcgtttttag aaaccgtctc aacgattgta
    40081 aagaaagaag aaaaataaaa atgatatgag atgcaggggg aagtatagtt gaaaaagaat
    40141 atggatgtcg aatggggcta ttctggagac aaaggtccgg aaaattgggc gagtttatgt
    40201 gattggtttg cgagaggtgc ggaatttcca ttgcagtcgc ctattcattt gaccaagggg
    40261 gaagaaacca aaatagaagg agacacgctt tcctttcatt atcaaaagca acggtttact
    40321 gacaaggaat tcaaaaacac gattcattta gtaccttttg accaactcag ttatgtagag
    40381 ttcaagaaag aacgctatta tttgacagat attcatttcc acttgccttc tgaacatatc
    40441 atcaacggaa aacaggaaga tattgaattt cattttgttc atatgaacag caaaaaagag
    40501 aatctagttg tgggtgtcat gtaccagcta atggtacagg aaggttggct gtataatcaa
    40561 gaaaatgggg aaagttggaa cttagaaaaa catgagcatt gggtaaatcc ggatgtgttc
    40621 tttccggagc aaaaaagcca tttccattat attggctcat tgacaactcc gcctaccagc
    40681 gggccaatcc aatggtttgt aatggatcat gtaggaaaac tgaaccaaga gtttcttctc
    40741 cccttcgatg gtcagtatgc tcgaccgaac aaccgaccaa tccagccctt gaatggaaga
    40801 gaaatttatt atttcgagga gtttgagcaa tgaatattca gcagatgaaa tacgtggtcg
    40861 ctgtagcaaa caatggtagt ttcagagaag cggcaaagaa aatgtttgtc tcccagccaa
    40921 gtctttcagc tggtatcaaa gaattagaaa ccgagttagg gatcacgctg tttactcgaa
    40981 cgaatcgagg ggcatattta acagaagaag ggcaagactt cttaaatcgt gccgagaaaa
    41041 tattggtcca gcttgataca ttagaaactc actatctaac gagtgaaaag agagacaatt
    41101 tttcgatcgc tgcccagcat tatgatttct taggtccttt gaccgcacag ctactcgagg
    41161 aattcaaaga cgagatcaaa caatttcgga tcatggagac gacaacagcg agagtgatcg
    41221 aagaagtcaa agagcagcac agtgagatcg gcattattta tatgaatgag cataatcaag
    41281 ctggtatcag aagatattta caacaaggag agctaagtgg ccgcagcatt ggaaaattca
    41341 aaacgcatat ttttttaagg caaggacatc cattagctga acacgcagag atcaccaaag
    41401 aagaattgtt atcttatcct caagttcgtt ttacacagga tggaaataat ttcccgtatt
    41461 tttatgaaga ccttatcgag atccctgatc aagaaacagt gatttatacg agtgatcgag
    41521 gtactttgat gaatatcgtt cttgaaactg atgcttacgc ttcaggatct ggtattgtga
    41581 ttggagggat tcgcgagcac ttgcggttaa tccctttggc agaaggcgaa ctaaatgaat
    41641 tttatatcat ttattcggcg aaacgtccgc tcagtgaaat cgctcaaaga tttatcaaag
    41701 agcttactcg gttactggac cagcagagct aagaaaagca gatgagaacg ctgtttattg
    41761 aacaccgttg atcaaaaaag aggggttgtg acagaatttt gtcacaactc ctctttttgt
    41821 agcaaacaat ttataactaa ttgctgttgt gggaaagtac gcaaatatga ttctagaaac
    41881 actcattgat tacctgtttt gtttcatagc tgtaattttt tcttcttctg gtgtcacgat
    41941 aatcgtcttt tggttttcat aaataacata accaggcttg gcgccatttg gttttcggat
    42001 atgctttacc tgtacaagat caaccggcac ttgggcagag tatcggtatt ttgaaaaata
    42061 ggcagctaac tcggcagctt ctgtaattgt ttcatctgag ggcttgtcac ttttaatgat
    42121 gacgtgcgaa ccgggtatat tttttgcatg aagccaatag tcggtttttt tagctgtctt
    42181 cattgtcagc tggtcatttt gaagattgtt tttaccaaca agaatgagcg ttccgtcaga
    42241 agaaaagtat tgatcaggct gagatggttt cttacgtttt tgttttttta agttcttctt
    42301 tttcaggtat ccttctgaag tcaattcttc tttaattgct tcgatatcca ttgggccggc
    42361 aatttccagt tgagataaga cagattcaag atattggatt tcatctttgg cttcttggat
    42421 ttgttcgcca atcagcttaa cagcgttctt cagcttttgg tatcgatgga aatatttctg
    42481 tgcattttga tttggtgtca atgccggatc tagtgctatt ttgattggcc gatcttcttc
    42541 ataataatta ggtaaaacaa cttcttttgc gccgcgtggt acttgtgtca gaaaagtagt
    42601 aagtagttcg ccatttctac ggtaattctc agcgttttcg gattctttga gtgtttgttc
    42661 acgttttttc aatttatttt tatttcgttt tagttcattt tcgatttttc gaatcagttc
    42721 tccgccttgt tgttttgccc gatctttctc tgctttttcg tgataatagc tatctaataa
    42781 ttgactgagt gttggataag ctgttacagc agatgcctgt tcggacaata cctgataagc
    42841 aatcggtgtg aaaaaatctt tattttccgt ttcgtaaaaa gtaggaatag gctgatggct
    42901 gatggctgag aaaaattcgt cccatacaac catcttttca ttaggacgtt ccagtaatct
    42961 tttggtcagc tcttgagcga tatcgaaacc gattccctga aactgacgtt ggattgcttt
    43021 tggatctagt tcagtttggg aaagccgctg aaagattttt tctttctcgg agctaaatgg
    43081 gttcaagacc tcttgttttg gcggagcaac atattctaca ccaggaagca aagaacgata
    43141 agtgttttga gagcttccaa tgtgtttgat cgcatccagt atttttccag tttctcgatt
    43201 aactaagacg atcgtactat gacgtcccat taattcaacg atcaatatga tattttgtag
    43261 atcacccaac tcgtttcgtt tagcaaagtg gaaatggatc actcgatcat tttcgatttg
    43321 ttcgatgtct tctaaaatag cgccatccaa atattttcga agcatcatca cgaagttagg
    43381 cggattatca ggattctgat aatcgatttg ggtaatctgt acacgagcat aacttgggtg
    43441 cgcagataat aataatcgat ggtttttgcc gcgtgaacga atcaccagca cgatttcatt
    43501 ttcataaggc tgatggattt tcgagatccg gccagatagt aacgtttcac gcaattcgtt
    43561 gaccatcgcg tgggtaaata caccatcaaa ggacatggtt cattcctcat ttcttttcat
    43621 aagtatattc attataacga aaaaaagaag aaaaaccaat ttggccgaat agtaaagcaa
    43681 aagtctagaa aaatcttgga ctaattacat aaaaaacagt gtttctatcg ttgaaatcca
    43741 aatttttagg tataataaaa aataggagaa aaagtagaaa agaaggtgtt tgttatttgg
    43801 gaagtagtta aatcgagagt acaagaaatg aatgaacatt tctcagtgtc attcgcagaa
    43861 aatccaagta agtattttcg acgtcttgtt tttctgctca tcttatcatt gctgttaaca
    43921 gttgcaatgt ttttattgcc ggaaaaaatc cgagaagagc aagtaaatag tctcgtttat
    43981 tcgtccatac caaccagcaa attgaaacct tttgattaca gcaaagctga tcagaaaatc
    44041 aaacaaagcc gggcgatatc ggtgatgttc agcaaaccga acgggaaaac ctatcaggac
    44101 atgcttgatg tttttaatga tcctgagctt atggaagaat tgaatcgacc gatcttttat
    44161 tatccgatcg tttatgatgt acatgaactg gaacaaaaat ataacatacg aacggatgaa
    44221 gtgacattta ttttctttga tggaggaaaa gaagcaaatc ggataactgc gggtaaggga
    44281 ggaataactg attttgataa ggagttgatc cctgaactga atcgacttcc gttagccaat
    44341 atcaaacaat tagaagaaga attggataga acgggagtaa cttcccaaaa ttccgagatt
    44401 gctaattgag acattggcgc gatgaaacgg tgggtctata tagcgctatt tttaattatc
    44461 agaacaagtg atgtttgatc ttcaaaataa caaataaaaa attaaaaaat atagttgacg
    44521 aaattcaaaa attcgattag acttaaatca attcttaagg aaagggtgac ctgtaatgaa
    44581 cttatcaaaa cgtatttcag cagaaaacaa aaaaaattgg cgcagctggc gtagataagt
    44641 tgtattaatg gtgagacttt cccatagata caacttttta gagtgcattt ctaaagcttg
    44701 tatctatgct agacatgaac attgactgcc gcatagatta gaatctatgc ggttttttgt
    44761 gtaaagacaa tgaccgcttt ggccattgtc tttttttgta gactggatac ttgcctgatt
    44821 ataataaata aaaagattga ctttgcagga ggaaaaaaat gaaaaacaaa cgattaataa
    44881 cagttgtagt aattatttta gtttatttag caggtgcatt tatttatgga aaagcctcag
    44941 gcgaaaaaga aagtacttcg acgaaccaga caaaaaaaac aacagttgtt ggggtattgc
    45001 aatacgtgag ccatccggca ttagatgaga tttatcgagg aatcaaagat ggtctgaaag
    45061 aagaaggatt aaaagaagga gaaaatcttg agatcaaatt tcaaaatgga caagccgatc
    45121 agagcaagct agccacaatg agtcaacagc tagtacaatc tgatccagat gccttgattg
    45181 gaatcgcaac acctgccgct caatcattag caaacacgac ttcatcgatc ccagttgtgt
    45241 taggtgctgt aacggatcct gtgggggctg gattagtcgc ttctttagag aaacctggtg
    45301 gtaatgtaac aggtgtttct gatcagccgc ctgttacttc acaaatcaag cttgcttctg
    45361 atttgttgcc aaatgcaaaa aaagtcggaa tcttgtatgc ttcttcagag gataattcaa
    45421 aataccaagt agcacaagca gaagaagctg caaaaaaaga agggttagaa tcagtaaaat
    45481 atgcggtgcc ttccactaat gagattgcac aaacggttca agtgatgagc cgacaagtcg
    45541 attttatcta tgttccatta gataatacca ttgccaatgc gatgcaaaca gtggtaaaag
    45601 aagcaaacaa agcaaatatc cccgtcattc catctgtgga tacaatggtg gaacaaggtg
    45661 gactagcaac aatcgggatc aatcaatatc aattagggct tcaaagcggt aagatggcgg
    45721 cagaacttgc gagtggaaaa gaaaaaccgg aaacgacgcc tgtttataca tttgatcaag
    45781 gggatacagt gatcaatcaa tctcaagctg atcgcttagg aatcattgtt ccccaatcga
    45841 tgaaggaaaa agccaaaatc attacagatg actcgcagca agaaacatct aaggaggatg
    45901 acaaatgatc gtatcagcta tttcacaagg catgctttgg gcaatattag gattagggat
    45961 tttcatgact tatcggatct tagactttcc tgatatgacg acagaagggt ccttcccatt
    46021 aggtgctgct gtctgtgtga cagctattac tcatggggta gcgccgattg tagctacatt
    46081 attaggcgta ggtgctggca tgatagcagg actcgttacg gggttacttt atacaaaagg
    46141 aaagataccg gttattttag cagggatttt agtgatgtca ggattgaact cagttatttt
    46201 gtttgtgatg cgaacaccaa atctttcttt attgaatcat ccgattctac aagacagctt
    46261 ccatcgcttt gggttacctg attactttga cacagtcctt cttggcttca tctctttggg
    46321 catcttgatt gctgtactgc tattcttctt caatacagat ttgggtcaag gctatattgc
    46381 gacaggagac aacgaaacga tggctcggtc gttagggata aaaaccgatc gtatgaaaat
    46441 tttaggttta actttgtcga acggtgtcat tgcattatcc ggtgcgctga ttgcccagaa
    46501 cgacggatat gcagatgtaa ataaagggat tggcgtaatc gtcatcggtc ttgcttccat
    46561 catcatcggt gaagtgatct tccaagaatt gacgctagca gaaagattga ttgctattgt
    46621 tgtcggcagt atcatttatc agctattgat tttagtagta atcaaactag ggtttgacac
    46681 gacttatctg aagttgttct ccgctatcat cttagctatt tgtctgatga tcccgcaatt
    46741 gaagaaagca ctgaacttaa aaacgggttt tgagaaggag gcatagtaat gactgatata
    46801 ttgacaatca aaaatggcag aaaagtcgta aacaatggaa tgaatgaaga gaaagtacta
    46861 ttggatgaaa ttaaccttac aatcagagaa ggggacttca tcactgtcct tggcgggaat
    46921 ggtgctggaa aaagcacact gttcaatacg atcgctggta cgcttcaact cagtcaagga
    46981 tcgatctctt ttaaagatca gctgatcaca aaagattcag aagaaaaaag agcacgattc
    47041 ctttctcgag ttttccaaga ccccaagatg ggaacggctc ctcggatgac agtagcagaa
    47101 aatttgctac ttgcacaaaa aagaggtcaa aaacggaaat tccgtttacg taacttgaaa
    47161 aatcaaaaag aagatttttt cagactatgt caagaagtcg gtaatggcct agagcaacac
    47221 ttggatactc cagcgggtga attatctggt ggtcaacgcc aagcattaag cttgctgatg
    47281 gcgacgatca cagctcctga gttactatta ttagatgaac atactgcagc tttagatcct
    47341 aaaacagcta aagcattaat gcgattaaca aatcagcgga tcaatgaaca aaaattgact
    47401 tgtctcatga tcacgcatcg aatggaagac gccttgaaat acggaaatcg tctgatcgta
    47461 ctccaaaaag ggaaaatcgt tcaagatatt tctgaaaaag aaaagcaaca tttgacaatg
    47521 ggcgaccttt tgcagttctt tgaagaagta gtggattgat ttcgacagaa aaattccttt
    47581 cagtagaagg acttgaaaac tcattgacat cttcctttga ttcatcctat acttaaaaca
    47641 ataaacaatt aaacatattt gggtgttttg taggatcacg tagtcaatga ttttaacaat
    47701 taaatagaat attctttgct ctgacaagta aacgatgaga aaagaatttg ctactttgcc
    47761 acctagacgt ttcgtacttt tt
//
LOCUS       DAJSMK010000012        47264 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.012, whole genome shotgun sequence.
ACCESSION   DAJSMK010000012 DAJSMK010000000
VERSION     DAJSMK010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 47264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47264
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.012"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(53..1477)
                     /locus_tag="ON488_000698"
     CDS             complement(53..1477)
                     /locus_tag="ON488_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3230914.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            1688..2134
                     /gene="nrdI"
                     /locus_tag="ON488_000699"
     CDS             1688..2134
                     /gene="nrdI"
                     /locus_tag="ON488_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCR3230915.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(2199..4181)
                     /locus_tag="ON488_000700"
     CDS             complement(2199..4181)
                     /locus_tag="ON488_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3230916.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDFAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(4195..5091)
                     /gene="murQ"
                     /locus_tag="ON488_000701"
     CDS             complement(4195..5091)
                     /gene="murQ"
                     /locus_tag="ON488_000701"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCR3230917.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(5094..6155)
                     /locus_tag="ON488_000702"
     CDS             complement(5094..6155)
                     /locus_tag="ON488_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCR3230918.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(6366..6932)
                     /locus_tag="ON488_000703"
     CDS             complement(6366..6932)
                     /locus_tag="ON488_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCR3230919.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(6960..8462)
                     /gene="eat(A)"
                     /locus_tag="ON488_000704"
     CDS             complement(6960..8462)
                     /gene="eat(A)"
                     /locus_tag="ON488_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCR3230920.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(8720..9841)
                     /locus_tag="ON488_000705"
     CDS             complement(8720..9841)
                     /locus_tag="ON488_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCR3230921.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            9967..10908
                     /locus_tag="ON488_000706"
     CDS             9967..10908
                     /locus_tag="ON488_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCR3230922.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(11058..11954)
                     /locus_tag="ON488_000707"
     CDS             complement(11058..11954)
                     /locus_tag="ON488_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCR3230923.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            12223..13563
                     /locus_tag="ON488_000708"
     CDS             12223..13563
                     /locus_tag="ON488_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3230924.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            13781..14224
                     /locus_tag="ON488_000709"
     CDS             13781..14224
                     /locus_tag="ON488_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCR3230925.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(14728..16146)
                     /gene="nhaC"
                     /locus_tag="ON488_000710"
     CDS             complement(14728..16146)
                     /gene="nhaC"
                     /locus_tag="ON488_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCR3230926.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(16549..17772)
                     /locus_tag="ON488_000711"
     CDS             complement(16549..17772)
                     /locus_tag="ON488_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HCR3230927.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(17803..18642)
                     /locus_tag="ON488_000712"
     CDS             complement(17803..18642)
                     /locus_tag="ON488_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCR3230928.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(18659..19339)
                     /locus_tag="ON488_000713"
     CDS             complement(18659..19339)
                     /locus_tag="ON488_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230929.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(19341..20414)
                     /locus_tag="ON488_000714"
     CDS             complement(19341..20414)
                     /locus_tag="ON488_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3230930.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(20470..20708)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(20751..20984)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(21061..21732)
                     /locus_tag="ON488_000715"
     CDS             complement(21061..21732)
                     /locus_tag="ON488_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCR3230931.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(21819..24497)
                     /gene="mgtA"
                     /locus_tag="ON488_000716"
     CDS             complement(21819..24497)
                     /gene="mgtA"
                     /locus_tag="ON488_000716"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HCR3230932.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            25156..25593
                     /gene="ndk"
                     /locus_tag="ON488_000717"
     CDS             25156..25593
                     /gene="ndk"
                     /locus_tag="ON488_000717"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HCR3230933.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(25615..26481)
                     /locus_tag="ON488_000718"
     CDS             complement(25615..26481)
                     /locus_tag="ON488_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR3230934.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(26641..28734)
                     /locus_tag="ON488_000719"
     CDS             complement(26641..28734)
                     /locus_tag="ON488_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCR3230935.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(29483..30106)
                     /locus_tag="ON488_000720"
     CDS             complement(29483..30106)
                     /locus_tag="ON488_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230936.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(30265..31662)
                     /locus_tag="ON488_000721"
     CDS             complement(30265..31662)
                     /locus_tag="ON488_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCR3230937.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(31694..32665)
                     /locus_tag="ON488_000722"
     CDS             complement(31694..32665)
                     /locus_tag="ON488_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3230938.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            33039..33464
                     /locus_tag="ON488_000723"
     CDS             33039..33464
                     /locus_tag="ON488_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230939.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(33952..34653)
                     /locus_tag="ON488_000724"
     CDS             complement(33952..34653)
                     /locus_tag="ON488_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCR3230940.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(34669..35109)
                     /locus_tag="ON488_000725"
     CDS             complement(34669..35109)
                     /locus_tag="ON488_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCR3230941.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(35109..35684)
                     /locus_tag="ON488_000726"
     CDS             complement(35109..35684)
                     /locus_tag="ON488_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HCR3230942.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(36532..37011)
                     /locus_tag="ON488_000727"
                     /pseudo
     CDS             complement(36532..37011)
                     /locus_tag="ON488_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(37170..37871)
                     /locus_tag="ON488_000728"
     CDS             complement(37170..37871)
                     /locus_tag="ON488_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3230943.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(37979..39388)
                     /locus_tag="ON488_000729"
     CDS             complement(37979..39388)
                     /locus_tag="ON488_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HCR3230944.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(39436..41301)
                     /locus_tag="ON488_000730"
     CDS             complement(39436..41301)
                     /locus_tag="ON488_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3230945.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(41422..42273)
                     /locus_tag="ON488_000731"
     CDS             complement(41422..42273)
                     /locus_tag="ON488_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3230946.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(42583..43296)
                     /locus_tag="ON488_000732"
     CDS             complement(42583..43296)
                     /locus_tag="ON488_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HCR3230947.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(43364..43690)
                     /locus_tag="ON488_000733"
     CDS             complement(43364..43690)
                     /locus_tag="ON488_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCR3230948.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(43813..44040)
                     /locus_tag="ON488_000734"
     CDS             complement(43813..44040)
                     /locus_tag="ON488_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCR3230949.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(44362..45615)
                     /locus_tag="ON488_000735"
     CDS             complement(44362..45615)
                     /locus_tag="ON488_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCR3230950.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            45676..46416
                     /locus_tag="ON488_000736"
     CDS             45676..46416
                     /locus_tag="ON488_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3230951.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(46502..47260)
                     /locus_tag="ON488_000737"
     CDS             complement(46502..47260)
                     /locus_tag="ON488_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HCR3230952.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
BASE COUNT        13623 a         9969 c         8100 g        15572 t
ORIGIN      
        1 tttttgaata aacgacaggc tcacaacctc tctttatact tcttttatac ttctatacgt
       61 gaagcatccc agtggcaaat aaaaccattg caatcactcc gaccatcgtc acacctataa
      121 gtaaaatctt atctaagtgg atatgttgta caggctcgtt ttgctcctta cgtgctttga
      181 ggtaaaaata aatgcctggc aagaaaagaa caagaacaag cattacttca ttaaaggcta
      241 cgactagcat agcccatact tgaaaggcac ttgctaaaag ccctactaaa aattggaccc
      301 attctttccg ctgataagaa agtttcattt ggtacaatcc taagaaaagc cacgtgaaga
      361 aaatagctgc tgtaccaagt gtgtaagcaa agttataagc actgtcagtg aataataatg
      421 aaagtaaaaa gacattcgta cataacgtcg tcaatacgat agcataagtt ggtgccccat
      481 ttttgttgag ttttccccat gctttaggca aaagtccgtc ttcagccatg tttcccattg
      541 tttcaatcgg taagatcgtc catgagagcc aaacaccaac taaagaaatg atcaaaccgc
      601 cgttgatcac gactgctccc catttaccaa ccatcatttc aaacacatag cccatagcag
      661 gctgcgcctt gatcgtttgc agctgattca tcgtcattgt cccatatgga agcatggaaa
      721 ccaagacgta aataataatc aagccgaata tccctagaat cgttgctttc ccaacatctg
      781 attgtttttt tgctcgtgaa cctacgacag aggctccttc aataccaaca aatacccaaa
      841 gcatcaccat gatgcaactc aatacttgac tggaaaacgg gatcggctgt ccattcgcat
      901 tcaatataat gtcgctagaa aagttatcaa tgaattgttg gatcgaaaac gtgctgatag
      961 ctactacaat aaataaaaat aatggcacta atttacagaa tgtgacgata gcattgacga
     1021 aactagcatt ttcgactccc cgattcacta gccatgcata tccccataaa aagactgtac
     1081 tcatcacgat cgatgccaga ttttgcccac cttcaaatac tgggaagaaa tatcctaatg
     1141 cgctcatcaa caatgttgca aaagctacgt tgcctaacca gcatgtgagc cagtaacccc
     1201 aaccgctgat aaaaccagcg aaacggccaa aaccttcttc tgcgtaacta aagatcccgc
     1261 cttttaaatc tggacgtttt ttattgatat tattgatcga caaggagagc atcaacattg
     1321 ctgttcctac gagtacccaa ctgaaaatag ctgggccgcc agccgatccg gagatgtccg
     1381 tcataatacc aaatacgcca cctccaatcg ctgaaccaat tactaaggca gcaagtggaa
     1441 ttaaaccaat tccttttttc tgttgctctg tatccatgta agcatcctcc aaaataaaac
     1501 cgcttttatc aaaaagtata acaaaccttt tttattttta cttaattaat aaaaacttta
     1561 atagaaatat aattctaccg gcttttttct cattatacaa gcaaagcgcc tagtcccttt
     1621 ccaaattaca ccaccaaaaa acttaaaaaa gatgctatac taaaaggaaa gaattggagg
     1681 atgatccatg aacattttat atatatcgat ttcaggaaat acgcgtgcct ttgccaaaca
     1741 tctagcagaa tatgctgaaa aaatgcatgc agaagatcct gtcaatcctg aagttacttt
     1801 aaaagaaatc catgaaaata gtgattttac gaaagaaaca gaaccatttt ttactttcgt
     1861 tcctacttat ttagacggcg gaaatggttt agataacggt gatacagaaa tcttgaccga
     1921 aacgatgcgt gaatatctgg aacatgaaga caatcataaa ctttgtcttg gtgtagtcgg
     1981 tagcggaaat aaaaacttca ataatcagta ttgtctaaca gccaaacaat atgcacaaac
     2041 atttggcttt cctttcttgg cagattatga attacgggga acaccatctg atgtgacacg
     2101 aatttatcag attttagcag aaaacaataa ataataaaaa agaagaagct gaaaaataga
     2161 tttcagtttc ttctttcgtt tctattgttt ctatcatatt aagctttgac atccatcaca
     2221 ggtgcttttg cttttgcttt acctgttttt tccaagacaa agttttttac acgatccata
     2281 ttggttacca agacgatcat ggatgtttct ttgcctgctg ctttgatcgc ttctaagtca
     2341 gcttctgcta caagcgtatc aggtgtcact tgctgccctt ctgttacttt cacatcaaat
     2401 ggcgtaccgc ctaagtcaac tgtgttgatt cccatatgaa gcaagatttc taaaccattt
     2461 ggcgttgtga tcccaatagc gtgtttcgtt gggaagacag agctgactac cccagtaact
     2521 ggagaataga tatgtccgtt ttctggttct acaaagtagc cttcacccat catcttttgt
     2581 gcaaaaactg gatcacttgc tttatctaaa gaaacaactg ttccgtcagc aactgatgag
     2641 aggatagtca cactttcagc tgaagtttga ggtactactt tttcaggcac ttcatttact
     2701 gtggctgttt cagtcgctaa ttcttctttt tctaaacggt ctttaggaat accgaagaag
     2761 aatgtagcaa cgaagccacc agcataagct gccaataatc caaggatgta gcctaaccat
     2821 ttaccgtcag agatcaatgg gatcaaagcg gctcctgaag gtccaatagc gatagccccg
     2881 acatttccga tcattccgat cactgccccg ccgatacctc caccgataca agcagtaata
     2941 aatgggcgtc ctagaggtaa tgttactccg taaatcaatg gttcgccgat tcctaggatc
     3001 ccgactggta aagctccttt gatcatttct gttaattctt tatctttttt gcagcgaatc
     3061 cataatgcca atgctgcacc cacttgtcct gcaccagcca tcgcaagaat tggaagcaat
     3121 agcgtacgac cagtttcatc aatcatttgc acatggattg gagtcaaaat ttgatgcagt
     3181 ccgaacataa ccatcggcaa gaataatgtg cctagaacga agccggcaaa tgctccacca
     3241 acgccaagta cccagttgat cccaccgacc atgccatcag aaatgaaacc tgctaaaggc
     3301 atgatgaaga aaatttcaat cagaccgatg gcaatcaatg aaagagttgg tgtaacgatg
     3361 atatctaccg catcaggtac tactttatgc agttttttct caacgattga caatagccaa
     3421 acagcgaaga tgacacctag gatcccacct tgtccagctg caagagcttc accagtaaat
     3481 aagtttttca gtggtgcttc cggattcatc cctgtcagca tcacaacggc cccgataact
     3541 ccaccaagag ttggtgttgc accaaaaact tgtgcagcat tgatacctgt atagataact
     3601 aggtagctaa acatcccgtt tttcaagatg ttcatcacat cgatatattg ttgccatgtt
     3661 gctgcatcaa gtgttccggc tgtgactaag tttgctaaaa ctgcggcaat ccctgccacg
     3721 atcccagtac cgacaaatgc aggaatcatt ggcacaaaga tattagaaat gtcttttaat
     3781 accgatttga ttttagatgg tttttgtttc gatttttgtg ccgctttcat ttcttgtgcc
     3841 cgttcgttta cacggtcttt tccagatgct gatgaatttg ctgtagctgt acttacagaa
     3901 gaaagttttt ctcctaattt cacgcctgca aaatcaacca tttgctgtgc tactttgttc
     3961 actttcccag gtccgatgat gacttgaagc tgttcatctt ctactacacc aagcactcct
     4021 ggaatcgctt ttaattcaga gacatttaca agatcatcat tgatgatctt catacgcaca
     4081 cgagtcatgc agtggacaat gctttctaca ttgcccatgc cgcctgcccc tttataaatt
     4141 tgttttgcca gttcttccaa agtcagttcg ttttttgcca tggtcttttc cccctcataa
     4201 ggtccctttt acaaatccgt ttgcttcagc taattttgct tgagcttcct ctttatcact
     4261 atttgtcaaa atcatgacga tagccagctt aacattttga tctgcttctt caaagtactt
     4321 ttcagctgtt tcgtaatcag cttctgtcgc ttgcatgatg attcgttttg agcgttcgat
     4381 tagtttttca tttgttggtt tgacatcgac catcaagtta ttgaatactt tacctatacc
     4441 aatcatactg atagtagaaa tcatattcaa gataagtttt tgtgctgttc ctgacttcaa
     4501 tcgagtagag cctgtcaaaa attctggacc tgcatcgact tcgattggga aatccgcgtg
     4561 tttactgatt tcggcttgtt tattgcaaga aatcgttcct gtgacagcac cgatcgattt
     4621 tgcgtaatct aatccaccga tcacatatgg tgtacgaccg ctagctgcga taccaataac
     4681 tatatcattt tttgtcaaat tcagcttgat tagatcttct tgccctagct cataagaatc
     4741 ttcggcccct tcgacagcta cagtcattgc ttcttctcca ccagcaatta gacctatgac
     4801 catttccggt tctacaccga atgtcggtac gcattcagca gcatctaaca cacctagtct
     4861 tccacttgtt ccggctccca tataaatcag acgtccacct tttttaaagg actcaatcgt
     4921 gttagcaatc actggttcga tacttgtcag ttctttttca accgcagcgg ccactttctg
     4981 atcttctttg ttcattagtt gaacggcttg agaaatactc atctcatcta atccaaaagt
     5041 ttcttggttt ctgcgttccg ttgttaggtt ctctaaattg attttgctca tttttatctt
     5101 ccttcttttc ttataaattg atagttcata ccagctttga tttggttgat caatggtagc
     5161 tcttctttga taactttagc tactacattc actttttcat ccgctggcaa atcatatttg
     5221 gttaattgga tctcacccat atagcgcaaa tacttttcgt tatctaaagt aatagaccct
     5281 ttcatacgcg tagctgtatt tcttgctggg ataggcggaa tctctcgaaa acgtgcatct
     5341 acgcttcgta tgacatctct tgcatcgtct tgccgattcg tatgcttccc taatatatat
     5401 tcgtaaaatt cttcatctac aggttccgta tggagcaaga ctgtctgttc tttttggaaa
     5461 gaagcaaatt gctcctgaac gttttctgac agacctgcat ctccgatgta aacaatatcc
     5521 gtgttacttg ctaatagatc tagagcgcct gcaagaggat ggatccctcg atgttcttcc
     5581 aaagttggca atccttgata tagtgggcct ctcaactctg tatctcctgg tacaaaacct
     5641 tggacaagga gaccttgaat tttgagccat tgattttttt tctgatacca ttctttgtcc
     5701 agccctgttt cgggacgtgg ataataatta tgccaagctt caatctgtga gaaatcagct
     5761 tctgcttctt tcaattcatc gatatcttta ggcgtgatcg tgctagcatt caaactgatt
     5821 ttcaattgat gtgaccagtc ggcaatctgc tgattggaaa tatgataatc cattcttaaa
     5881 cctgttacac caattgcttt caaaggcgtt agatcttcta atgaaaaacc cgctcgttcc
     5941 aatgcctctc ctgaaatatc gaccatcaat tctagtttat tctttttcgc ttcgcttcct
     6001 agttcgatca atcgcttttg atatgccgaa acatcatctt ctggtatatg catggaagtg
     6061 aaaataccga caaagccatt ggatgccatt tggcggatat actgtttctt ctcttctgac
     6121 aaagaatcgt tcataaatat tgaaaagcca aacatattat ccctcttttt ctgtatccgt
     6181 cttcatttct atgactagag tatatatcta aagaaacaaa atttcaatac ttttattaaa
     6241 ataattaaat ttcatttcta aaggttgagt ttatattatc aaaagaattg tcataaccta
     6301 aaaaaggcac tgctaagcaa aagcagtgcc ttgaaatatt ttatttaaat aacacaaaaa
     6361 cataattact cataagaaac caattctgta ttatctacca tgaatgtaaa gaacccctca
     6421 ttaggcatcg gatgaaaata agcattgatc actcttatca aggcattatg gcaaactaac
     6481 agatagacat tttcttcgtc ttcgatgcat tctttcaata aaggaacgat ccgtgcatac
     6541 acatctaaga ctgactcccc atttgggaat cgtacagcga acgctaaacg tgctttttga
     6601 aagttctcat ctttgcttgg cagtccatca taatccccaa aatccatttc taccaatcgt
     6661 tcatcaacgg tcagcggcaa gctgagacga tcagcaactg cttgtgctgt atctcttgct
     6721 cgttgaagag gggaatggat gattttcgtg attggaacag gcaaatctac taccttttct
     6781 gctagtttct gtgcctgcat ctgtcctttt tcagtcagcg gcacatctgc ccgtccgcaa
     6841 actaatcctt gtgcgttcca agttgtttct ccgtgtctcg ttacataaag catgtgattc
     6901 tctccttcgt tggcaaagtt ccccttaacc ataccttgtt gttcttgaga ttacaagggt
     6961 tagattctct caagagaaat aatctcagta gatactttat ccaggaaggt ttgatcatgt
     7021 tccactagta acatggcagg tttcacgttc aagatcagtt gttctaattg ttcttgattg
     7081 aagacatcca aataattcaa tggttcatcc catgtatata gttcagctgg ctgtgataaa
     7141 gatttagcca attccacttt tttccgttgg cccatactca tctgctcgat cttgttatga
     7201 aaaacatctc tttccatccc aagctttcgg aggttgttca aaaatgcttg gtagtctact
     7261 tggtttttct ctgcaaattc cgccaacgtt cctcgattgt cttcataatt ttggcttgca
     7321 taactaatgc tcagatgttt tggctggtat ttttctccta taaccttgcc gttgaatgcc
     7381 cccagaagat aatggataat ggatgacttt cctgcaccgt taggacctga aatcgccacc
     7441 cgctgatgag gctcgattgt aaaatgaatt ggctcgaata acagattttc ataccctaat
     7501 tgaagatctt ctacgcttaa aagtcgctta tggtgagacg cttggctatt catcgtcaaa
     7561 gaatcgatat attcgatatc ttttaatagt ttttctttct cgctgatctg ggtctccatc
     7621 cgattcacga ttgctttgga tcgtttcatc gtccgtgcag catcagcacc cactgctcct
     7681 ttattcactc gtctagattc agtatcgatg aatccgactt gtttctttgt tttatctcct
     7741 tctcgggaac gagaccattc ggctttttca gctgctgttt tctttagcct actgacttct
     7801 tttttcaatt tttcattttg agccatttca aattcatcac gaagtttttt ctgttcttca
     7861 tagatagaga aattcccttg ataaagttcc agttgacttt tttcgattgc taaaacatgg
     7921 tccactactt catcgataaa tccccggtca tggctgacca cgatgaagcc ttgttttttc
     7981 tttttcaaat aagccgctac ttgttttcta ccagagatat ccaaatgatt cgttggttca
     8041 tcgattaacg ggaaatgagt gtcatccaca aataaaagtg ccagtaggac ttttgtcttc
     8101 tctccccccg atagtgtgct gaattctctc cataagattt caggatctgt ttgcatcaat
     8161 tggagctctc tttcgatttc ccatatctca aaatccgtaa tatcatttaa cacgtaatag
     8221 gttaaacgtt ctttatcttt tgtctgttgc gggaaatagg caaattcttg ctgatggatt
     8281 acttgccctt gataaggtag tttgttttgt agaatattca gtaaagttgt ctttcctcga
     8341 ccgtttcgtc cgataagtcc tagtttccat tgtgtgtcaa aatttagatt tgcttgttca
     8401 aataataatg tgccttggct gtcgtagccg aatgtcagat tttttatttc gattttagac
     8461 attttccatc acctcgtaaa aaaagaccag tcctattttc agaactggct aaagaggatg
     8521 caagggttgg atacacacaa aaagacccat acatcgaaaa aaccaagcca atcccgaaaa
     8581 tctgcacact gcttccttgt ctccacaagg tacagtctga atgcagcttt catcaatcga
     8641 cttaattttt caatgcacgg atccctcact ttgtcctata tttgaaatta cgatagcata
     8701 aagaaaatga ttttgtcaac tacttcggga ggatggtgaa aaatctgcta agtgtctgtc
     8761 ctaagatttt tgttttttct aatgtttgcc tgtgttccat tgcttcttct aaacctattg
     8821 gacccaaatg aatacttaag acaattggga gaaaatcaga aagtccttct agctcttggt
     8881 ctctacttcc gcaaatagcg attattggtt ttcgatattt ttttgcaagc actgctacac
     8941 cgtatggaac ttttccgtgg atcgtttgct gatcgatccg cccttctcct gtaatgatga
     9001 catctgcttg ttcgatcttt ttttccaatc cagtgatttg gctgactaaa tcgaaaccag
     9061 aaaccatctt cgctcccaac aaaaaaaggg ctccaccaat accgcctgct gctccacttc
     9121 ctggaatatc atctaaatcc acctcccaga aatcttttat ttgctgagca atctttcctg
     9181 cttgtttatc taagaaagct agcgtcgtat ctattcctcc tttttgtctt ccaaattgcc
     9241 aagcagctcc ttgttgacct gtatatggat tggtaacatc tgcagcgata atcaatttta
     9301 ctttagaaac aagaacgttt cttcgatcaa aatgaagttt tttagtagat aataaaggat
     9361 ttccttctgt gtacccttct aaagaagcac ccaaggattg gagtaatcct agaccaccat
     9421 cgctacaccc gcttcctcct aaagtgacaa taatttgttc tacttcttga agcagtgcat
     9481 ctttaataag ttctcctaag gcataactgg aagcaagtcg gatagtttga tccgttggtt
     9541 tatcaagtag atctaacccc aatgcttgtg cagattcgat gactgcggtg ttttttcctt
     9601 gccaagttgt caataaatag ctgatttttc gctgacggaa taagagatcc atcccatcaa
     9661 tggtacgcca tgttcccctg agcgcgtaat agattgcttc tgcagtattt tctccgccat
     9721 ctgcaatcgg cacattgatt tttcttcctt tacgatcttc ccagccattt agaactgcct
     9781 gatttagttc aaatgaagaa gcacttcctt taaatgaatc aattgccgcc aaaatatcca
     9841 tctgtatccc tcactttctt cttaagtaag acactttttt tcattttttt caaacaaaac
     9901 aatgctattt tcttccattt ttctatatac taaaagggaa ctcattgaat aaaggagaga
     9961 aaaaacatga aaatcgcaat agctggggcc ggagcaatgg gcagccgaat cggattgatg
    10021 ctacatcaaa gcggaaatga ggtcctcttg atcgatcgtt ggcctgctca cattgaagcc
    10081 attcgtacaa atgggttgat tgctgacttt aacggtaaag aagtggtcgc aaaactgcca
    10141 atctattcac cagaagaaat catcgaaagc aacgaacacg tggacttgat cgtagcatta
    10201 acaaaagcca atcaattaga tgatatgttt tgttcgatcc aatccattat tactgacaat
    10261 acttatgttt tgtgtttact aaatggatta ggtcatgaag atgtactgga aaaatatgtg
    10321 ccaaagaaaa atatcttatt tgggatcacg atgtggacag ctggtctagc tggtcccgga
    10381 aaagtcacat tgttaggtga tggagaaatc gaactagaga acttggaacc agaaggcgaa
    10441 gcatttacaa aaaaagttgt agaagtcttt caagaagcaa atttaaatcc gatctatagc
    10501 cataacgttc gttattccat ttggcgaaaa gcttgtgtaa atggaacatt gaatggttta
    10561 tgcacgattt tggattgtaa tattgctgaa ctaggcgcgc aaaaagcggc agagagcatg
    10621 gttcgaacaa tcgtatctga atttgcttct atcgcagcaa aagaaggaat catactagat
    10681 caagaagaag tgtaccaaca tattgcttct acttatgatc ctgacaacat cgggttgcat
    10741 tacccatcta tgtaccaaga cctgatcaaa aaccatcgtt tgactgaaat cgactacatc
    10801 aatggtgcca tttggcgaaa aggacaaaaa tatgatattg ctacaccata ttgtgccttt
    10861 ttgacccaat tagtccatgc aaaagaagga atccttggcg cagaataaaa ggctctctga
    10921 tgagaatcag ctgaatcagc agctggttct ctttttttaa gcccaataaa agatcaaaaa
    10981 gaaaacacaa ctctcatgat gccataagaa ttgtgcttgt ttgtttcagt acataatctc
    11041 ttcaaaatgt aggtttttta tttgttttca acagaggaga ggtcatattc gtattgctca
    11101 taaatagtgg aatcgttagt gataaatcgt tttgcccaat tttctgcatc ataaaattcc
    11161 aatagctctg ataggattgg cttaaatggt gtatgcagaa attccggtaa ttcatctaaa
    11221 tcacgttctc gaagcaaaaa aatattttca ggacgataaa aatgataatg agcaatcgct
    11281 tgattatccg tcactagttt cttttgaaaa tacatggatt caaatgtccg caaagtcact
    11341 ccttgctgac cctcccgcaa cagttccaga atcccgcgcg attcccctgt ttttttcagg
    11401 tactcttcat aagtaagata tccaggttgt tcattccctc gatgtggaag aatgaaatag
    11461 ttggtcgtaa catctctttt tataaattcc tgcttatagc tttctgctcg ttcttttctc
    11521 ccattattcg ttgcaccaaa aaatagatcc gtctttggtt cgctagaaga aaaattcata
    11581 tgtttcgaat aaaatgaact attatgtttc agcccaagtt cttttgcttc caaaaaatca
    11641 aaatgataaa tctcatcgat tgccggttca tcttgtgcct gcttcagcat cgcctcgtgt
    11701 tctgctttga agtgattcca aaaaaataac acaatttttg cattggtaaa tgggcgcacg
    11761 cgtcgagcca tctccatatc aaatccataa tctaaaaaaa cgatcagctg ataatttgcc
    11821 aactgttgtc tagctgattt aatgaattcc gactgtagta aatcttttcc ggaccaaaca
    11881 tctaaagagc ggatggaagg caaaaaataa agtgatttat tttttgcaac tagcagtacg
    11941 tcatttttgt tcatcttttc cgcctcactt tctctgtcac tttttcctat gatagcctgt
    12001 ttaaatagta aaaagccagt aaaacgtttc ctatatttgt atgaaaattt aacatttgta
    12061 tgaaaatatg atgaaataaa tcattcttct attaaaattc gcctaaaagt tttctgaata
    12121 gttgtaattg tctgaaaatt tgttatcatt agtcattgtt aaatattgct atttattctt
    12181 aatataaatt ttgattgtga atttaaaaga aagaggtcat ttatggaaga taaaaaattg
    12241 aaaaaacaac ttagctccag acatatcacc atgttagctt taggtggagc aatcggtgca
    12301 ggtctattta aaggaagtgg cgaagcgatt gggatcgccg gcccttctgt attgattgct
    12361 tttttgattg gtgggctgat tttatatatc gtgatgaaag gtctgggaaa aatcgtttta
    12421 agcggtggcg acacgcatca cggattatct ggtttgatac gcccttatct aggtgctcat
    12481 tctgctgatt ttactgattg ggtctactgg tctatgtgga ttatcaatat catcgctgaa
    12541 gctgttgcag ctgcttcctt tttgcagttg tggttcccgc acattccagc ctgggtattt
    12601 gtttttatgt tggctgtttt aactacgatc atcaatcttt attcggtacg gttattcgca
    12661 gaaacagaat attggctggc ttttgctaaa atcagtgtca ttatcttact gatcattttt
    12721 gctacttatc ttgtcggtca gcaaatgttg ggcacaggcg ttttccctac ccttcagcaa
    12781 ttgactgacc atggtgggtt tactcctcat ggtatgaagg gaatcatcag ttctttgctt
    12841 gtagttatct attcttacgg cggttctgaa ctgattgcta tcacggtaag cgaagcagat
    12901 gatcctaaac gtgcgattcc taaagcaatc aaaggtgtca tgggaagaat catttccttt
    12961 tacatcattc ctttgttttt gcttttgatt ctttttcctt ggaatacttt agcaggcacg
    13021 aatgtcagtc cttttgtgat ggtatttgaa aaaatgaata tcccatttgc agcggatatc
    13081 gtcaattttg tgattgtcct tgctttgttc tcatctatca attcgggtgt gtatgcatct
    13141 tcaagaattt tgttcttccg tttgaaggat cgaaaaggtt cctctagaaa actagctgtt
    13201 ttaaacaagc atcaagtacc gcaacgtgct gttttatttt gtaccagtgt tctttatctt
    13261 ggtgtagctc tttcttattt tgtcggtgac aaattatttg gctatctggc aggttccctt
    13321 tcgtatacag tattattgat ctggatcatt atcagtgcgg catcctttgt actggcacta
    13381 agaaaaggaa cattatggga taaaggaatc agcttttttg cattagctgt cttaggattg
    13441 attttccttg gtatcctgtt cacgaactcc attggggtaa ctgtattgac tggcctgctt
    13501 tacctgttca tttatttcag ttatcaaaaa aagaatgatg cgttcgtatt gacgaatgaa
    13561 tgaaatcgat agaaaatttt attttattta tgtggaatag atggagctat tgaagaaagg
    13621 agttgtgaca aaagtcttgt tgcaactcct ttttccgaat aaacagtctc atgacctctt
    13681 ggtaaacggt gttcaaaaac cctctgtgca aaataattga ttgttctcca tgctcatgac
    13741 atgatagaag aaaggaatga aaaaaaggag tttgttttaa atgaaaaagt attggaagtt
    13801 tttgttgatg atcggtgttt caacggtagt tatgtttggt atgatgtact tgaatgtcta
    13861 tgcgctcgat catatcttct tcagtcgtac acgagtattc atggcgttga tgatgggtgc
    13921 agtcatggca gtcatcatgc tgttgttcat gtggaaaatg tatgaaaaca aaaagataaa
    13981 tgttatgatc ttagccgcta gtcttcttgt ttttgccggt tccttgttta tggtacgaag
    14041 ccaaactact gtcaacgaca cagcttggat gaaggccatg attcctcatc attctatcgc
    14101 tatcctggca agtaaacgag ctgatttaaa agatcctgaa gtaaaaaaat tagcggaaga
    14161 aatcattcag gcacaagaag aagagatcga caaaatgaaa aaaatgatca aagaaatgga
    14221 atgaccatta tccgtccaaa taaaaaaaga ggatgttcca gaagttatca gcttcaagaa
    14281 ataagaagaa gctacttctg gaacgccgtg aataaggggt tgtgaaaaag ctgccctgca
    14341 tcaagtaata agaacagcca aacaaaaata gcttctccta tttttcgttt ggttaggctt
    14401 attaccgcag atgcaagctt ttgaacaccg tttattaaga ggttgtaaaa tcagcgttct
    14461 gacctgagta ttagagagac aaatggaaaa atagttcctc atattttgcc attttttgag
    14521 ctaataccga gggtcagctg attgaacacc gtttatcgag aggttgtgaa aaagtcgctt
    14581 agtttcgcgt attaagaaaa attttgtgaa atggctttcc acatttttgt ataaatttgg
    14641 cttaataccg agaaactggc ttttgaatac cgtttattcg taaaagggat tgtgacaaaa
    14701 gtcttgtcac aatccctttt tatgttttta ttgttctaat tgcgctgtct tgcttactgc
    14761 ttcttgcggt ttcacaaatt tttttgagat tccccaacct gtgaaggcac tgaccatcga
    14821 aaacacagga gaaagcaaac tgaaaaatac gaatggcaag taagtgagtg taggaatacc
    14881 aaatgtactt gctacgaaac ttccggcaat tccccaaggc actaagtagt tgattactgt
    14941 tccaccatct tctagcgttc tacctaatac agttggatca aatcctgctt tttcataagt
    15001 ttctttaaat gcattaccag gcagaataac agataggaat tgttcaccaa taaaaatatt
    15061 tactccgata cttgtcatca atgttgtaaa aatcaaattt ggtgtgttcg tcatctttct
    15121 tgatactcgt tccatcacgg ttgagatcaa gccaaattcg atcaacaatc cacctaatga
    15181 caaagttaga ataatcaatg acacagtagg catcatactt tcgattcctc cgcggctaag
    15241 cagtgaatcg atttgttggt ttccagtatt tgaaacaaac cctgattcga tgaccccagc
    15301 caacttcgtt aaggaagttt gtgggttttg aataaaaatc attcctactg ctacagcgat
    15361 attcaacaaa atcgttaaaa ttgccggcac ctttttccat gcacacagta acattaaaaa
    15421 taaaggaatc agtgaccaga ttgaaatagt aaagtttgct tctagaacat cagtcacttc
    15481 acgaatagat gaaagacttg cggctttact tgtgtgtcct aaaatcatga ataaaaagaa
    15541 agaaacaaca aatgccggga cagttgacca catcatatgc ttgatgtgtt tgaacaaatc
    15601 ggcatcaaca atagctgctg ctagatttgt tgattcggat aatggagaca tcttatctcc
    15661 aaaaacggca cctgaaacaa tagctccaac aaccagcgct ggatttaagc ctagtgttgt
    15721 cccaataccg aaaaatgcaa tcccaatcgt tgacataaca gtaaaggcac tccctacagc
    15781 gctacctacg attgcacaca caacaaatac agaagggaca aaccactgga cactgatcaa
    15841 tttgaaccca atgaccatta gagttggaat gatccctgct tgtatccata cagcaatcaa
    15901 tgaaccgact aaaataaaaa taaagattgg gatgattcct ggtttgatgc cattgatgat
    15961 tccttcgtgc agccaatctg tcgggtatct ttttatcact gcatacaaca tgaccattcc
    16021 gatcgctgct aagatcgtga tattaggtga gacctttaat ccgacaacgc caatcgcaat
    16081 gcctaaaaca ataaccatta atacaagtgt tgcttctaaa aaacttggtg ttcctttttt
    16141 tcccatgata atctctcctt ttttagttgt tcttatgttc taaaaaagtt aagatatcgg
    16201 attactccgc cgcaattcat ccgcgattcc tcctttataa aaataaaaag acctgtttta
    16261 aactaaggac gaatgactcc gcggtaccac cttaattaaa aacagatctg tttttcactt
    16321 tcaaactttt attcaaatgt atggactttc catgtaattc gtcaattagg cttgatcggt
    16381 tcacagcgac caccgacttt ctgaacaaaa cacctaaccg ctactgcgtg aaaagttgac
    16441 ttgtacgaag tttaccttcc ataagatcat ttgtcaatga aaaagaaaat attttttcat
    16501 ttttctgaaa attattttta taactttcac acacaagttt attttttact agaaagtagc
    16561 gccctcttgt ttttttcttg ctactatttc ttgatgttct tgcttgattc tttctaatag
    16621 ctttggctct ttcaacagat caagagctgt attggcgagt agttctgctg caatcgcaat
    16681 agaagcaagg cctttgtcac ttttagcagc agctttgaat tcttctgtgt gtccggcaat
    16741 atatgtctca gagattgcta ccgtaggctg gattgttggt atgacttggc tgacatttcc
    16801 tacatcagaa gaaccgagac ttgttctttg ttccgtttct atttcttcat ctggaacacc
    16861 tgcttctttt gcatgctgga agaataagtc atcaaaagaa ggagtaacga tgacatcatc
    16921 aactgcattt tggaacaatc caaactcaaa agtcgtgccc gtacttatcg cagcacctcg
    16981 tacgatattt tccacttttt catatacttt atctaatgtt tgccgatttc ctgcacgtaa
    17041 atagaaacgt ccagcagcgt aatctggaat gacgttggca gctactcctc cgtctgtaat
    17101 gatcccatgg atattgacat cttttggcaa ttgcaagcgt agagcgttga ttccattaaa
    17161 cacttggatc aatgcttcca aagcatttac tcctttttca ggtgctgctg ctgcatggga
    17221 agcgacaccg taaaatttga tgtcgactgg atcattcgct aaagattctg tcgttttccc
    17281 ataacgaaaa gctggatgga cgcataacgc tacatcgaca tcctcaaaaa aaccttctcg
    17341 aacaaagctg cctttagctg atccgttctc gcccccttct tcccctgggg tgccatatac
    17401 acggatttct ccaccagttt catcaatgaa ttgcttcact atgctggcgg ctaatacgga
    17461 gtaagtacca aacaaattat gcccgcatgc atgaccaata cctggtaaag catcgaattc
    17521 tgccaaaaag gcaattgtgg gaccgggttt attggaaata taacgtgcat caaaggctgt
    17581 tcggtgtcca gctacttctt tttctaccca aaacctttct ttttctaatt gtttaatcaa
    17641 cgctgctgag gaataaaact catagttact tacttcagga tgttcgtgga tatctagagc
    17701 aagtgcttga tattctggta aacgatattg gattagatcc ttcaattggt ttgttgagat
    17761 tgttgttgtc ataaaaaatt cctcctatgc tagtcatttt tcttattttc tcccgaatgt
    17821 ttcccatgca ggcacgcttg atccttttga tgttttctcg attactttga ctgtgtcttc
    17881 tgtttgataa gcgtctacta ttttttgata cgttttattg ttttcatctt cttttcttgc
    17941 aacgatgata ttcacataag gacgtgcatg gtcatccact ggttctaaga agatggcatc
    18001 agaagcagga ttaaatccag catctacagc tacaccgcta ttgatcactg aaatgtctac
    18061 atctgacaaa gcacgtgctg tttgggaagc atctaattca gaaatgtcta gattttttct
    18121 attctcggta atatcagaaa cagtgggcgc ttgtcctttt gccttatcca ctttgatcaa
    18181 tccagcagtt tgcaataaca gaagagctct gccgccattt gtaacatcat tagggattgc
    18241 tacttttgct ccgtctttga tatcagctac atccttcaaa gtgttagaat aaattcccag
    18301 cggtgcattg acagtatttc cgatcgatac taaatcagtt ccgtgttctt tattgtaatt
    18361 gtctaaaaag aattgatgtt ggaaagaatt caaatcaatc gatccatctg ctaaagccac
    18421 atttggttga ttgtaatctg taaatttcac gtattccaaa ttaatgttct cctttttcaa
    18481 acggtctttc acgttgtccc atacatctgt atcttctcca ataatcccta gttttacgat
    18541 agtttctttt ttgtcagttg tatctgcttt tccttggcta caccctgcca accaaataat
    18601 tgctacaaat gtaatgacta caaaacgaat aatttttttc attttttctc ctccactttc
    18661 aatgtgtaat ttttttaatc agttgattac tgataaattg acttaaaaaa actaagatta
    18721 gaatcaataa tgtagccaca atcgttacat ctgtttggaa tcgattatac cctctcgata
    18781 tagcaagatt ccctaatccg cctgcaccta ctgctccagc catggtagtc agtccgatca
    18841 cgttgatgat agtcaacgcc gagacccgaa tgataccagg caaaccttct aacaaataca
    18901 cacgtaaaat gataccgatt ggactggttc ccatcgcttc tgccgcttcg atcaccccag
    18961 gatcaacttc tagcagtgcg ttctcgattt gacgagcaaa aaacggaaca actccaaaaa
    19021 tcaatggcac taaagctgct ttcgcaccaa tcgtcgttcc aactaagaaa cgagtagtca
    19081 atgctaaaag agaaagcaag ataatgaaag ggatggaacg aatgatattg atcagcttat
    19141 caagtatttc aaatagcaga cggttagcta gtaatccatt agggcgtgtc actactaacg
    19201 tcacacctaa gatgattcca atcatcccgc caatgaatgc tgtccaaaaa gacatatata
    19261 gtgtttgctt cgtcgcttcg acaaattcat ccggaatcaa ataaacattg ggcaaatatg
    19321 ttttaaagaa atcagtcatt ttatcttcct ccttcgatca ctttgatacg actatctaaa
    19381 tcgttttttt gtaaaatatt tatttttaca ccagatttga tcaaataatc caatgctttt
    19441 ttccgctgtt tggtttctcc agctaaagta acgatcaaac tccctaacgg cgtttcttgt
    19501 aataactcta cattgccata taaaatattc gctgttactt gatatttgct gtacagatga
    19561 gcgattagag gttcgttcgt ctgatttcca atataactta attccaccag ccatttattg
    19621 gcgatctgat cggcaaaagc agaatgggca atgatcgttt ctaatgcttg gtcaagatga
    19681 gtagctgttc gaataaaatc tttggtcaat tcttcttcag gattgctgaa gatctggatg
    19741 ctgctacctt tttcaacgat tcttccatct tccataaccg ctaccttgtt gcagatttct
    19801 ttgacaactt gcatctcatg agtgatcagg acgattgtta aacctaactg gcgattcaat
    19861 ttttttaaca atgcaaggat ctgaagggtc gttttcggat caagtgcact ggttgcttca
    19921 tcacataata ataccttagg ttcattcgcc aaagctcgtg cgattgctac tcgttgtttt
    19981 tgtccccccg acagttgttt aggataagca gatgcttttt cttccaaacc gacaagttcc
    20041 agtagttcat tcactttttg acgacgttcc tgtttcgatt ttccagaata ctttaaagaa
    20101 aaatcaacgt tgtcaaaaat agttcggctt tccattagat tgaaatgctg aaagatcata
    20161 ccgatggcct ttctttcttt tcgcaattct ttgggagaga gctgactcag attcgtctga
    20221 ttgacaatga cttctcctgc tgttggtttc tgcagcaaat tcatcacacg aactaacgta
    20281 cttttccctg cacctgagta accgacgatt ccataaacat cgcctttttc aatcgttaaa
    20341 tctacagaat ctactgcctg tatctctttt tctttttgtt tgaaacatac agaaacatct
    20401 cgcaattcaa tcattaaaat tcctccttat ctaaaaaaag cgtcctcaag aaaatgaaaa
    20461 tgtcattttc ttgaggacgc ttttttgcgt gttaccacct catgttcaag ctgtgttcac
    20521 acacaactcc tcttcaagta cgatcatact ctagcaagat atcggtcgca gccgtcatcg
    20581 ccttacatct atgctcggga tgaattgctc gatggccatt ttccaatagt cgttccttgc
    20641 ttcttctcag ctaccgaagc tctctgtcaa aggttcttct atcgtactta ccatttcaat
    20701 gcaaataata ttcaaaaaaa aagtcctttt actaacataa actatgtcag taaaaggacg
    20761 acgtatcgcg gtaccacctt ttttcggaag tttccttccc tcaagcccaa catctcaaaa
    20821 agagagattg gcgttcgttt taacggtcga acagttccga atttgcctac ttatcgacaa
    20881 attattctcc aaggccattt tcagcttttc ttacttgact cttctcacca gccagagcct
    20941 ctctgcaaag tttccaaact tactttcctt ttcaacgaaa tcgatatttt gttgttggga
    21001 ttaatctaca tgaggaaaac tgaaaagtca agtacgaaat tcaaattatt ttttctatat
    21061 ttatttttct gtttttttat ttaacatttc aataacagtt cgaagatctt ttccttccgc
    21121 aagaagtttc aatttttcct tttcttcgac ggtataattt cggacaaaac tggaatcagg
    21181 tatcaaaaca acgcctaatc ctgctcgtga agcagctgtt gctcctacta aagaatcttc
    21241 cactgcaaag gctgaactag cttctaatcc tgttcgttcc aaagctgtca gataaggaat
    21301 cggtgaaggc ttgttctccg acacttcgtc tccgaatgta aacgtgtcca agtaatcagc
    21361 taatttaaag tgatccaaga tatctgttgc tcttttcgta acagtggtcg tagcaatgcc
    21421 tagtttcata tgacgttctt ttaagtctgc caatatttct tttgcatatg gttttaagtg
    21481 gatggctccg cttgtcagct gttgataaaa atattcttca cgcttcgctc ggacttcctg
    21541 tactttttca gggctacctg ctgctttcac taaaatatca aaactttgtt tccagttttt
    21601 tccgccccaa gcatcaacga tttcttttgg gatatggata tcaaattgct gaaatcccca
    21661 aagccagcca tcacgatacg ttttttctgt gtcaactaac aaaccatcta aatcaaatat
    21721 tgcacctttc atctatacat taatcctttc caaaacaata cacatagttt agcacgactg
    21781 gtccaaaaag aacagaagca aagaaccagc cttctcgttt ataagagttc ttggaatcga
    21841 cggatataga ttttcttcac agctgtcaca agcgccagat aagcgatgac tgtagcaaat
    21901 aaccataacc agtaattgcc aggaagtggc atcaagccta attcagcacc aaaacttgta
    21961 aaaggaagga cagaaccgac aataattcct aatgtagtga taacaaacat ggcaaatgtt
    22021 gcgttgcttt ggataaatgg tactttcggt gtacgcagtg catggagcac taaggtttgt
    22081 gtccatagtg attcgacaaa ccatcctgca tggaataatg cgatgaaaat cactcgctgt
    22141 gaactatcca atgtatggaa acttccgccc actacagcag gacaaataac aaaatacatc
    22201 aacaagtaag tagtaatatc aaatatcgaa cttgttggac caaagtaaac catgaattcc
    22261 ccaatactag atgcattcca tttttttggc tcgtccaaat attctttatc catccgatcc
    22321 catggcaagg aaatgcagga aacatcatag atcagattca aaaacaaaag ttgtaaaggc
    22381 agcattggta aaaatggcag gaacgtactt gcaatcagca cggaaaacat attgccaaaa
    22441 ttagaacttg ctgtagcctt gatatatttc atgatattcc caaaagtttc tcgtccagaa
    22501 agaaggcctc tttccaaaat cgtcaaatct ttttctaaaa ggatcacgtc tgcagattct
    22561 ttcgcaatat ccacagctgt atctacagaa ataccgatat cagccacttt cattgcagga
    22621 gcgtcattga taccatctcc taaaaatccg acagtatgac catttttacg taaagctgtc
    22681 gtcaaacgtg ctttttgctg aggattcaat tttacgaata cttcatggtc ttcagctact
    22741 tgtgctaatt catgatcact catttccgag attttctcac cggtaaccaa ttcattgatc
    22801 tctagaccta cttgacggca cactgaacgt gtaactaatt cgttgtcccc agtcagaact
    22861 tttacagcta caccatgttc tttcagagct ttcaacgctt gtttcgttgt ttcttttggt
    22921 ggatcaagga aagcaagata accaatcaaa accatgtctg actcatcttt gactgaaaat
    22981 tctccaacga cgcttggatt ggtcttttgt gcgacaccaa tcactcgtaa gccatcttca
    23041 ttaagtgact gtacttttgc aagtacggct tcttttcgtt cttttgttaa tggtgtaaca
    23101 gtaccgccaa gatcaataaa tttagaaatg ttcagcattt cttcaatcgc gccttttgtg
    23161 atcatttgtg ttttaccagc tggatcagca accacaacac tcatacgacg acgttcaaaa
    23221 tcaaaaggaa tttcatccac tttttgataa ttgatcttat ctgtatctaa agtttctgtt
    23281 gcttcatcaa tgatagccac atctaacaaa tttttcagcc ctgtttgata gtagctattt
    23341 agatacgcat ggcgcaaaac acgatcatct tcatttcctt cacaatccat atgatattca
    23401 agaatgattt tatcttgtgt caatgtcccc gttttatccg tacataacac atcgattgca
    23461 ccaaagttct ggatggcatt caaatttttg atcactgttc cttttttggc catcacactt
    23521 gctcctttga ccaaattcgt cgtaacgatc attggaagca tttcaggtgt tagaccaact
    23581 gctacagata gtccaaaaag aaaagcttct agccaatccc cttttgtaag cccattgatg
    23641 acgataactg ctggagccat caatgacata aatttgatca gtagcatgga tgttttatgg
    23701 atgcctaatt caaagcttga ttgaattggt ttttcagata gcgtttctgc tacatgacca
    23761 aatagtgttt catttccaac agaaacaatg attccttccg cacttccact gatgacatta
    23821 cttcccataa agacaagatt ttcgtaactt gtttcgcttt gctgatcgtc ttcacatact
    23881 ttcgcatgct tttctactgg atagctttcc cctgtcaatg ctgcttggga aatgaataaa
    23941 tcctttgcgg acaataaacg catatccgct ggtatcatat cccctgctga aagccgaaca
    24001 agatctccac agacgatttc ttccatagga atctctgtgt actttccatt acgttttaca
    24061 gctgccgtta ctttcacaag tgatttcagt ttttcagccg cttgattgga acgtacggac
    24121 tgaatcaacg tcattgtccc gctgacgata accatagtga agataatggc tacaccgaaa
    24181 agatctttat ctccaggagc tgctaataca tattccgtga tgaatgaaat aattcctaat
    24241 gcgatcaaca ctaatgtaaa tggcgtgatg tatgctttca atatttctac aatgaatggt
    24301 gtttttttgc catatgaaat cgcattttca ccgtaatttt ctcttgaacg ttcgatttgt
    24361 tcttctgtca atccatttgc tgatgcatgg aatagttcaa ataattcttg tttcgttttt
    24421 ccagcaaaag ctgcatagat tttttgtgta tctttctttt tttccatctc aatctctcct
    24481 ttgtgtccaa aagacagctg ttctcgctgc ttttggtctt tagctattca tcggatcgat
    24541 agagaaaaaa ctgaaagggg ctgagaacag atagataata gccctggcct ttcctctaga
    24601 tccttgtttt tcgaatgact gtcatccatt tgttctcatc tcctttacta agtaatttta
    24661 attcatgact tccaatcatt tttcgaatag ttatttttcc aattagacca cctccttttt
    24721 atttttcacc gatggggatt tgcggcaaca aaaaaacctc tcgccaaata ctcagcgaaa
    24781 ggtttgaaaa agcatattaa aaaaagcttc tcagatctca tcgttgagtt ttgacactgt
    24841 acaacgtaaa aagcagatac ctgcttttag ctaccttatg aaaagcctta tctcgacaat
    24901 tcctgttcta cccattggcg tctctcgacg tttttgggca gtagcctatg tttgtatagg
    24961 agcctcacct aacaaatctt attcggtttt ccttcgttaa tataacaact aaaaaagagg
    25021 atgtcaaatc aattttccat gtttttcata ctttttttaa aatacacacg ttatattcct
    25081 gtctcacgcg gttttatttg tctcattttc cacctcccgc tataatagaa atatagtagg
    25141 aaacgaggtg ctgttatgga aagaacactt gttattatca agccagacgg cgtgagacgc
    25201 catttagtcg gaagcatcat ccaacgtttt gaagcaaagg gactggccat tgctgaaatg
    25261 aagtttgaaa ctatgactcc tgaattagca aaagaacatt atcagcactt gactgagcgc
    25321 agtttttttg atgaactgat cgattacatg acttccggtc ctgtcgttta tcttgtgctg
    25381 gtcggcgagg aagtgatcga tatcgtccgt aagatggttg gagcaacaaa agctgccgat
    25441 gctgttccag gtacgatccg aggagactac gcgctgccgg ggactgaaaa catcattcac
    25501 gcttctgatt cccgtgatgc tgcggtaaaa gagatcgccc gctttttccc gccattcgat
    25561 ataaacaaac cgtctgaaaa agcggcgaag tgatacaaat tctaaactgc tggtctagtt
    25621 gctgggttca gcaatggcca gcagtttttt ctctaaggac ctccgttgat tctttcctaa
    25681 catatattcg agcactgtga agaattcttg gtagtctttc gtcttttctt cccctaaagc
    25741 agcagaaatc aatctttgat aataatctgc catcaatgtt tcatagatca ctgtacttct
    25801 ttctttatgt gctaagctcc gtttcatatc ttcattcaca ctacgtgcct ttttcaaccg
    25861 accattttct atataaaacg aagtcaggtt cattaaaaaa gtaaagagat actgctcatg
    25921 attgttcaac tgtgctaatc gtcgcattct ttttttgatt ttcaaataat tgttctcaat
    25981 gaaccgatca ctgaatatcc aaggaaaatc agctagaata gatagttcaa attgaccata
    26041 gtctggtatc tgcatcaagt attcttcaat gattcggcat tcataacgta aaaattcaaa
    26101 ttctgtctca gatacttctg ttttttcgac catgtgaaga ttcaaaacca aataatacag
    26161 atcttctgtt ttcttaaaat gcctacggtt attgctgatc tctttataag gatcaaagct
    26221 gtcttcttgt acccgatcta gcattcgtct ttttttcttt aactttattg gttcatccag
    26281 ctggtttcgc atccattcat attctgcaag tgtcatgttc attcgctcta aaaatgatct
    26341 caatgttaca aatgacattt ttttcactga atttgtctca atcccgacta gagaagtctt
    26401 aaaacagatt ccttccgcta attgggactg tgtcaacttc ttgttgactc gaagtttctt
    26461 gatcaattca ccatcataca taatagttct cctttttaat ttaaattttt ccacattcaa
    26521 taaatagata cgttaaaaag gaaaaataca cgaaaaaaat aaaaaaatgt ttttttcata
    26581 aaaaatacca accttcaagc attagaatgt tgtctaacta ctgaaggttg gtttgattgt
    26641 ttattgatta tttttttgct gttcaacgtc tgttcttgtt actggatata agttggttgt
    26701 tgttttatta ccattttttg aaaagacact tgtcgaatgt tcgccttttt gcttttcgat
    26761 tgcttcatta cgttccgctt catttttata gtcatatttt ttcggatcaa tcgtctcaaa
    26821 tccgtttggc acataaaacc gcaagagatt ttcctgattc agcttatctg aaagacttaa
    26881 cgcagtcttg actttttcct gatctttgga gatttcctca tcgattcctg ctgctttcgt
    26941 atcgatgatt tctcctgtct gattattgta agcttttcct cctaggacgg tgtatttggg
    27001 tgtcacaaag ttcccatttc gaaaagcaac tacttgatca tgctgagaag ataataagtc
    27061 tgtaccaaaa tgaagataat ctttatcatc gattcccaat agatgtagta atgtcggcaa
    27121 aacatcgatt tctccaccgt attcatgatt gactgtccct ttagtataac caggcatatg
    27181 gatcatcaat ggcactcgtt gcatctgtgc gttgtcaaat tcatcccatg tatctggatc
    27241 tttaccaaga gcgcttgcta aatctttatt atctgtattc gagatcccaa aatgatcccc
    27301 gtaaatcaca aagattgaat tttggtaaat accagatttt ttcaaatacg taaaaaattg
    27361 ttccaatgat tgatccagat aatgtgccgt tcgaacataa ttatctactg tgctattgcc
    27421 agtattcaaa gatggaaagt cgaaattctt gtcatccgta taataaggcg tgtggttggt
    27481 tacggaaaga aatttcgtgt aaaacggctg ttgtagatgc tcaagatatt gggcagattc
    27541 tctgaataaa tctttatcta atatcccata acctaacgtt tcgtcggatt catcaaaata
    27601 agatcgatca aagaaattgt cataacctaa gtttttatat acatgatctc tattccaaaa
    27661 actagctaca ttcccatgga aaacagcgct tgtatagcct tgcttttgtc caaggatcgc
    27721 tggtgcggct tgaaagacat tgtctgaccc aagttctgtg aataatgagc cttgaggtaa
    27781 accaaatgtg ccagtttcca acatattttc agcatcactt gtctttccct gtcctacttc
    27841 atgaaagaaa ttgtcaaagc tgatcgttgc ttgattctgg aaaatactat ttaaaaacgg
    27901 tgtgacttct tgtccgtcta ccttcatatt aatcaaaaac tgctggaaac tttctaaatg
    27961 gagaacgatc acatttttcc ctttagcgat cccaaatgtt tcgggatttg gctctgcata
    28021 atgtttcttt gtataatcta aaacttcatc aatcccatta ctgcttgcat gcgcgcgaac
    28081 actgctagtc attcctgttt tgattccgtc ataaatagta tacgcatcga ttcctagata
    28141 tttgacaata tatgaacggt caaatgttcg ctgcagcaat tgtggacggt tggcttcgct
    28201 cagcgctaga tttcctgaaa aaataagccc tgaaagacag gtaacagcga tagccatcgg
    28261 tttgccgaca gggttgcttt tgataggtat tttcttgacc ttcaaccaaa ccagtagccc
    28321 aatgaacaca gcgatatcca gccagtagat gacatcatgg ggcttcatca aagaaaagga
    28381 gcttcctgac aatccttgcg acactttcga aaagcctaat acagatttga ctgtaatgaa
    28441 atctgtgaat tcccgataaa aaataatatt caagtacaac aaaagcgtat ttaaaatatc
    28501 aatgatcaaa agaatagcta acgctggctt tggcttttta atatacaaag aaaggccaaa
    28561 aaacaataag gtagtcgcaa ttgggttgat ccacaagata aagtactgga tcgtaccttc
    28621 cacacctaat gaaaaatctg catagtaggc aatgatcgtc ttcagccaga aaaagaaaac
    28681 agctgtcaaa acgattgcta aacgattttg gcacaatttt ttaagttgtg tcacgtatat
    28741 cacttctctc tattcacatt ttttcttatt ttgctcctga aaaatgaaaa tttcctaaaa
    28801 aagttgttat cttaagattt ttttattctt tctaaagatt attccgtcca cttttcacag
    28861 cataaaaccg ctgcgatgta agcgattaaa ctaatgaaga gataaaagtc ttgtggtgac
    28921 cgcttcactc cacggtattc aaaagccagt ttctcggtat tcgtacaaaa aaagaggctg
    28981 tgacaaaatt cttgtcgcag ctccttattt cttgatgcag gacagctttt tcacaacttc
    29041 ttccttaaac ggtgttctcc tgccaactcc tcggccacaa gtcacaatat ttataaaaca
    29101 tgagaagctg ttttttgaaa ttgttccttg tggctcagag ttaaacggca ggctcaagac
    29161 ctcttgatac acggtgttca atcagctgac cctcggtatt agattatgtc aggacgctaa
    29221 ttttacaacc tcttggtaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc
    29281 aaacgaaaaa tataaggagc tattttttga aattgctcct tgtggctcag agttaaacgg
    29341 caggctcaag acctcttgat acacggtgtt caatcagctg accttcggta ttagctcaaa
    29401 aaacggcaaa atatgaggaa ctattttgcc gtttgtttct ctaatactca ggtcaaaacg
    29461 ctgatttcac aacctctgtt tttcattgtc cataggattg atattgtcct tgtgatgact
    29521 cattcgtaat aattgaggct tgattttctt cacttcccgt tatcgtttgt ccactgccag
    29581 aatctgaagg acttgttcct gtcgactcgt ttttttgaga agagacagtt gttttcttga
    29641 cttgttcatt tgtctttttc cattccgcta aacgatcggc gaccactttt ttgtctactt
    29701 tttcagaata agcggtgatc acttttccat ttttcaaacg ggctactttg tcgccatcat
    29761 gagtcaaaag caaaacggtc aaatgcttgt ctttaaattg atattgtctg agagaaatcg
    29821 cactaagtac gtcatcgata ttaataaatt gattttcttc ttttcctttt ggcaaataaa
    29881 tgtccaattc gcctttttcg taattggcag ttattttata ctccgcccac caataagttg
    29941 agaattcttt tttgaaatta tctactgatt ctttgcttgc tacgattttt tctgtttctt
    30001 tctgagcaag atctgctgtc atttttcctg aaaatgctgc ggataaaata agcagtaaga
    30061 aaaaaccgaa taaccaaaag agaagaaacg gtcttttttt cctcatgctt tcctccactc
    30121 ctatttaatt ttgactattc tattatatac aaaaaatgaa atagaaagac aaaaaagttg
    30181 aaaaagatcg taaataattg aacttctttt tcacaaaatg gtaagaatgg agaatttcac
    30241 gcatttgctc tcaactattc tttcttaagc ctcaaatccg tttttatctg atacgtcttt
    30301 gaaccaatga cccgattttt tgattgttct ttttccatct tgtgctaagt ctactgaaat
    30361 aaagccatat cgattcttat atgcattggt ccacgaccag ttatccatac atgtccacat
    30421 atgatagcct aaacaattgg caccttcttg aatggcttga tggacatatt tcagatgaga
    30481 ttggacaaat tcgatccgat aatcatcgtg gatcatgcca tcttctttga taaatcgtgc
    30541 ttcgttttct acacccatac cgttttcaga aataaagcag tcgatatttc cataatgatc
    30601 tcgtacattg atcaaaatat catagattcc ttgttcatag atctcccatc cgcgataagg
    30661 attcatttta cgaccaggca tttcataatt gtcgaaataa tcctcaggca ttggaccgtt
    30721 tttagtatcg attggtgttt cttttgcttt tacccggcgt ggctggtaat aattgatacc
    30781 taaaagatct actgtatttt ctttgataac cgtcaaatcc tctgcatgga tcacaggcat
    30841 gagatcaagt tcttttacta tctcaatcaa ttcacttgga aactcgcctt ttacagctgg
    30901 atcaaggaat gaacgattga agaacgcatc tgctatttgc gctgctttaa catcttcagg
    30961 gtttgattcg tctcttggat agcttggtgt cagattcaag atgataccaa taacaccacc
    31021 ttgctccatt tcatggtaag atttgatggc taacgctgaa gccaacgctt catgatagcc
    31081 aacttggatc gcttttttca tatctgactc ttctggataa tgccatcgat ataaataacc
    31141 tgcttcgact ggaacgattg gttcattatg agtaaaccat ttttttactt tcgaaccaaa
    31201 caattcaaaa caacttttgg catatttttc ataggcttca accgtttctc ggttcaacca
    31261 tccgcctttt tcttgcagat acatcggcat atcgaaatga tacagattca caaagggttc
    31321 gataccgttt tcaatcaact catcaaaata acgatgatag aaacgaacgg cttcttcgtt
    31381 gattgttcca gattcatcag gtatcaaacg gctccattgg atagatgttc gaaatgaatt
    31441 atgcccagtc tgtttcatca actgtacatc ctcttgatac ttcgtataaa cttgcgaggt
    31501 tttttcaggt cctacttgat caaagaactt ttgcggttct tttttgtacc aataatcaaa
    31561 aatgttctct ccttttccat cgcctgaaat ccttccttct gtttgtgggc cacttgctgc
    31621 agaaccccac caaaaatttg ctggaaattg atattttttc atcaaagcac ctctttttct
    31681 tttttagttc gttttagttg attccatgta tgatattttc catcacaatc actttttcat
    31741 tttcttcctc ttcttttttg attcgtttta acagctgttc tgctgctcgt tccccgattt
    31801 tatctgttgg tggcgtgatc gtgattttcg gaaggatact cagatcgttt ttatctaaat
    31861 aatcatagtg actgaacgca atatccttcc cgattctgac accttcttga ttgaaacatt
    31921 cgatggcacc aatcgacata ttgtaattgc tgacaaaaat agcagttgcc cctttttcta
    31981 ataatgcttt tgccccgtaa tagccgcttt ttctagaata gtctcctgta aagacctcta
    32041 attggatcga tggatcattt tggaccgctt ctttggctcc tgctaaacgt tctcttgcta
    32101 cgtagtctgt ttgagtggca gcaataaatc cgattttttt atgtccttgt tcaccatgat
    32161 gagcgatcac ttttgctaca ctttctcgat cattcactaa tattgtatca atacctgctg
    32221 gtccttctgg acaattcaat gcgataactg gaatactcat ttttgtgagc atttcaaatc
    32281 cagaccactc ttcttcggat aagaagacaa tcagcccatc gatcacatgc ttcatcaggt
    32341 attcaatttt ttgttcaatt ttttctggct gatcggcaaa cccgcttaat aataagctat
    32401 acccattttc ttcagctact ctttcgatcc ctgagacaac ttccgaccca aaacggctgg
    32461 aaatcccgtt tatcaaaagt ccaatagaga agcttcgatt attcttcaac cctttagcaa
    32521 tgatgttttc tttatagtcc aacgctgaaa tcgcttctgc tatttttttc atgttctttt
    32581 ccttcagttg ctgaccattc aagtaacggg aaactgttcc cactgaaaca ccagccatct
    32641 tagccacatc acggatcgat gccatacatt ctcactcctg ccagttacat ttgatttctc
    32701 tttcttgttg ttcgattatg atgaccgcat tctttgcata gtgttgcttg tcatcaatat
    32761 ccatataact aaagtcttca gtagagcaac ttcctctcac tattaattat acttaaacaa
    32821 gtatttgaac cggttcattt ttaatatagc atttttttaa aagattgcaa cactttttta
    32881 aaacgctttc tgaaagtggc ggattttttg cctttttaaa attttattct aaaatttact
    32941 ctatttgtgg gtgttttgtg cgtttttctc ttccatccgt ttgaagtttt acattccaat
    33001 ggtataattt ctttatccta tcaaatgggg gaagtatttt gaagaaatta atcgtactat
    33061 ttattttgtc tgcgggactt ttgacattga ctggctgtga tttgtttggc ggctctgacc
    33121 aatcctcgga cgaaacaacc gattcttctg tcttaaaagc ggaaaaagca gataccacca
    33181 acagtgtata tacgctaaaa gtacgtaaag atatggattt atccgcggga cagttgacat
    33241 ttacagataa aaaaatggaa tggacacgca cgtatcagac acaaggaact gattcttctg
    33301 aatcatctga agaaaaaaca gtgctgacag atatcaagat cactaccaaa gatgacgaat
    33361 atattatttc aggaaaagaa aataaaaaag aaacaacagt catatttaca aaaatcggta
    33421 attaccgttt gaaggatgag gatggcaaca tctacagtct atagtgccgt ctgttggatc
    33481 ttcttttgtt tctccccttc ttttctgcta tagtaaagaa gcaagatgat tgtaaaggag
    33541 acgaaatgga tgatcgatag tcctgattat tgtacatgta ataacaacaa aaatatccat
    33601 acagaattta atgaccaagg aagcttgagc atatgcgaca actgtcacaa actagtcaaa
    33661 gattcattta aaacatttga atcttatcct gttcaaaatt atgtaaaaag tagaagaaga
    33721 taaacaaatc caagcaaaac tcactatggc tgatttttat gaacttcaaa ctcagcttct
    33781 tcctttgatc aagcttcatc agtaaaacaa acagtggatc atttcagttt acaaatcaaa
    33841 gagtaaagat ttatttattt caaatatttg aatataaaat aaccaaacga tagaaaggct
    33901 tattctacat cacgtagtaa tttttctttc ccgtcgtttg gttttttatt tttagcctaa
    33961 ttcttgacct tttgcatgct ggttatccgt aaaatatttt ccagcaggct ttccttccaa
    34021 ttcagctaat ttttcttgga tctgacggat cacctttttt gcatcttctg gattttctac
    34081 aaaatcgaat ttatccccat ccacttgtat tttaggacat acatcaaaat cttcatacca
    34141 ttgattatag cgggtgttca acgtttcata ataggtatat aacgtctcat cgctttctag
    34201 ctgttcatag tcacgcccac gttttttgat acgttctagc atcgtgtcca aagaaacttt
    34261 gatatggacc atcaaatcag gccgtttttt tggagcaaca tcatctaact cgtttagcat
    34321 cgtatctaat aagctatcgt actgctgtac ttcgatatcc gttacccgac ctaaatcagc
    34381 gtttagatgg aacaacaggc tatcttcata gatggatcgg tctagcacat tgtcatcgtt
    34441 cactaaagca tttttcattg ctaaaaatcg cttgttcaaa aagaagattt gcaataaaaa
    34501 agcgtactgc tcaggatttg aataaaagag cggcaatact tcgttatctt cgacattttc
    34561 ataaaatggt ttagaatcaa tctcttttgc aagcatatcc gtcaaactgc tcttacctgc
    34621 accaatcgtt cctgaaatca aaatcactga catacaaccc ttcctcttct ataagtactc
    34681 gcctacgtaa gtttcaacag gcaatgtttc aaaatcatat tcacgtacag cttggtctga
    34741 ttttaaatac gtatggagac tttgtgtaat catcaagttc gtaggtaccg tctcttcttg
    34801 tacaatgatc atcggttttt tcaacatagt tgccacacct aattcgtaag ccgttcctgg
    34861 atcgattgtt tgatgctcaa agtcaaggat agcaacaaca aattctgcat ttgtcagttc
    34921 ttccatatct ttttcgtata cttcctgcgc ccatccagcg ctgaatagtt cataattgct
    34981 ttcttggtga tgacgtggag agtagaaact tgtgactgtt ttgttttcct ccaacgcttt
    35041 ttcgatacga cttactcgat cgatttgctc ctctgaaaaa aatggtcctg ctaaatatat
    35101 ttgactcatt attttgcctc cttcaataat aactgatttt taatagatac tgctcgtaat
    35161 tcattgacca gttccaatgg attgttggaa aagattactt gatccaacca ttttttatcc
    35221 ataaaatcct cttttgcaaa agtttctaat aattgttgca agccgctgta ataaccgcca
    35281 atattcaata ttccgattgg cttgtcgggc gtcagaccga ttgctatcca agaaagaagt
    35341 tgtgagaatt cctccaatgt acctagacct ccagggaaaa cgaggacagc atctcccttt
    35401 tcaaataata atacctttct ttcatcgatc gtttctgtag gaataaatgt agtaacatct
    35461 tttccaggca attcagtttc aaaaagccca ttcggataga tacctgtgac ttttccgtta
    35521 ttttccagta ctgttttact aatcactccc ataatcccgg agtatgaacc accgtaaacc
    35581 agttcgattt cttcttgtgc catgtatttt cctaacgttt gcgcaataaa tttgtaactt
    35641 tctttattac caaaacggga accgcaaaaa acagtaagtt tcataaaaaa acactcccta
    35701 actcaaaagt ctatcttcat tctacacgtg tttttttaaa ataaaagact agattttgta
    35761 gttttttagt ggtatatagg atagacgcca ctatatatag tatttagaaa aaaatcattt
    35821 ttcagccatt ttatagataa aacaaaaata aataacgtgt tttcatcgat atgaaatgac
    35881 ttacttatag aagatactgg gatttcgtcc tatatgccaa taacgtgtat tattttaaac
    35941 aacaaatact tgtttctttt attaacgaaa aaatcatttt gttctcgtgt tatgtttcac
    36001 tgataaatga tgtttctcta aataaaaaag ccgacgaact aaacgatcaa aatttgatca
    36061 tttttgttca tcagcttctc ctaaaaatct ttttgttaac gataaatagc tggatttgta
    36121 aaaatatcac ttgaatcgtc actgctggaa gaaaattcag tgataaccgc acctgttgcg
    36181 cctgcctgga actagtgttt gatattgggc tcgaacgtgt actgatctct agcatgaaga
    36241 ataatttctt tttttactgt ataataactt tctttccttt ttggaatagt acaggaaagt
    36301 ttttttgttt cctttccttc gacataaggt ataccagacc ctttcgacaa cgaaaggttc
    36361 tcatttttcc ttcatcgtca tttcaaggag ggtgccgatg ctctggacag tttcgatcgc
    36421 tcctaaacca aaatctgtat attcgattct ttctaactct gattctttca taccattcct
    36481 gtctcaaggt acatctattg tacttttttc ttgtaatcca ttctgcctct cctaactaat
    36541 tgtcaaatca tcccaagata tgtcttcttc ctctttttct tcttggatga tttctgcatt
    36601 cggatctact ggttttttca ataataaaat ggttattcct gtgacaaaag aaccagctaa
    36661 caatgcacca atgaatgccc atggtctggt catcgtagcg actgcaaaca ttcccgatgc
    36721 cggaatacgg ctatctgcgc cccaaaacat gcttaatccg ccacctactg tcccaccgac
    36781 tcccgttgct atgacattgc gtgccaagtc gttcaatacg atagggaaac atccctctgt
    36841 gatctgacag atccccatag gaaaagcggt cttcaatgta tcgatttctt gacgattgag
    36901 tatattttta cgaatgattt tccctaagaa ataagcgatc gtcaagccga atggggttac
    36961 catcgaagct aaaatcaata cagtgattgg ttcatagatt ccttctgaaa atcgtgccac
    37021 acccccttat ccagaataaa tggtaatcca gaaacagccg tgtatctgcg gtaataagcc
    37081 taaccaaacg aaaaatatga gaagctattt ttgtttggct gttcttatta cttgatgcag
    37141 ggcagctttt tcacaacctc tttttttatt tatgtttcat aatcaatatg gtaaggatgc
    37201 agctccgtat ggtagaccgc ctccgaatat tcaatcattt ccccaatttg cgtagacgat
    37261 ttccgtatcc gtttgatgcc gatctgtgcg tctgttttca gaattccttg ttcttcttct
    37321 gttaaaaata ctgccgagaa atcatcagaa aatgagtcaa tagtatatcc ttttttcgtc
    37381 agcaaacgat acaaagattc tttgccaaat tcttctctgc tgaattgcat catttcttgt
    37441 ggaagataat gaacaaaata aatataaggc tgattgttca aataatataa gcgcttaaaa
    37501 caaacagctt gctcaccgaa aaaggaaaac aaaggatctt ccttctttat atggaccaat
    37561 tgcaaatcca gcgtttcttt ccggacttca tatcgggagt tctccaagat ttgcgtaaag
    37621 cttgccgctt tggataatcg attgtaagga cgattgctta gaaccgtcgt cccacgacca
    37681 cttttctttg cgacatattc atctgatgcc agcagttcga ttgcctttcg gacagtgatt
    37741 ttgctgactt gaaacagttc ttctaattca ctttctgtcg gcaacatcga accgactgga
    37801 tattttcctg agaaaatatc ttctttaatt ttatctgcga cttccaagta tagtacacgt
    37861 gtccttttca taacgtcacc ctttgcttta ctattactaa aagaatagca cataaaaaat
    37921 aaaaaaagaa cacaaatcac atgtgagaag tgtgttcttt ttcattcagc tgctttaatt
    37981 acaagtttac gccatttgag gcaattactt ctttatacca atcaaaagat tttttctttg
    38041 atcgattcag tgtcccattt ccttcatcgt ctagatccac atagataaag ccgtaacgtt
    38101 tactcatttc tcctgttgat gcactgacaa gatcgataca tccccaaggc gtatagccca
    38161 tcaaatctac accgtctgct actgcattag ccatcgcttc gatatgacga cgtaaataat
    38221 cgatccgata atcatcaata atcgtgccat cctcttccat atgatcaatg gctccaagac
    38281 cgttttcaac aatgaataat ggtttctggt aacgattgta taattcattc aatgcgattc
    38341 tcagcccttc tggatcgatc tgccagcccc attcacttgc ctcaagaaac ggatttttta
    38401 ctcctcccag caagttccct tctgaagttg ctgcttgtgg atcagtctca ttgattgccg
    38461 tagacatata ataactaaat ccgatgtagt ccactggata ttcttttagc aactggaagt
    38521 ctttttccgt ttgctctaat ttttccggat cgactccata ttttttatgg gtacgcgctg
    38581 tgtatgcagg gtattctcca cgtacttgga catccgtgca gaaaaaattg aattcttggt
    38641 tttggatcat tgttgctgcc tgattgactg gattggcatc gatgctgtaa gttgttgcat
    38701 agataatcat gcagccgatt tggatatccg aacgcaattc gtggccgatt tttacggctt
    38761 tgctacttgc aacgaattga ttatgccatg cttggaaaat attttggtac tctcctgctc
    38821 cattgctttt tactaatcct tgacttaaag ctggaaagtg aaaggccgaa ttgatttcat
    38881 tgaaagtcat ccaatatttg actttactgc tgtatctctc taatactgtc tgagcaaatc
    38941 gttcatagaa gtcgatcagt tttcgatttt tccagccacc gtattctttt gccaaatgaa
    39001 gaggcatttc gtaatgagaa atcgtgatca caggttcaat atcatatttt aagcactcat
    39061 caatcagctg atcataaaat tctaatcccg cttcgttagg agtaccttcg tctccatttg
    39121 gaaaaattcg tgtccaggca atcgaaaaac gataacattt gaatcccatt tccgcaaaca
    39181 aggcaagatc ttctttgaaa cgatcgtaat gatcgattcc tcgatgattc gggtaaatat
    39241 atttttcttg atcaatcgtc cagtcaaatt cttcactgcc gataatcgca aagcgctgct
    39301 tacctccagg catagcatct gcaacggata gtccttttcc gtctcgatca taagcccctt
    39361 ctaattgatt tggcagcagt tgctccaccc cataaaaatt tttctgaaaa acgtgattgc
    39421 atcctgattt cctccttatt ttacaattgc cagaacatct tcgtttgcaa taatctcttt
    39481 ttggtctaat tcaagtatat cggcaaatgc atcagtattc gtaatgacaa ctggagtgat
    39541 tacgctatag ccagctgctc taattgcttc gatgtcaaaa cgaatcaata aatctcctgc
    39601 tttgacgaga tccccttgtt tgactaagat ctcaaagcca ttcccattta attctactgt
    39661 atccatcccg atatgaatca aaatctccgc tccgtcagtc gttgtgatcc ctacagcatg
    39721 tccagttgga aaaatagtcg tgatctctcc gtctgcaggt gcaactagtt ctcctacttc
    39781 tggatcaata gcgatacctt ttcccatcac gccagaagaa aaaacttggt ctggtacttc
    39841 actcaatggc agtactttac ccgttaaagg actttttaag gtatgccgtg ctgaagtaat
    39901 cggttctcct gcattcgcat gtttgttttc taattgattg tcttgtgttt gttcgtcaaa
    39961 tcctaaaatc aatgtaccta cgaatgcaag aacaaaagca attcctgtag ctattactgc
    40021 tactgtcaca tttgactcta caccatccac cgtattaatg aaagtcggaa tcgtcaataa
    40081 gctgaccaaa ctgctggaga aagcttttac tccggaaaat ccgataatag ctccaccaat
    40141 acctccagaa atacaagcgg caatgaatgg tttcttcaaa ggtaatgtca caccatacac
    40201 agttggttca gtgattccaa ataacgaagt cactgtagaa gaaatcccta atgctcgaag
    40261 tttcgtatct tttgttcgca atgctacagc taaagcagcc ccaccttgtg ccaagatggc
    40321 tggaagaagc attggcatca atacatcaaa cccatattgt tcgatattca aaaacatgat
    40381 cggtacgaat ccccaatgca tgccgaacat cacgaatact tgccataaac ttcccatgat
    40441 tagacctgct acgattggac taaatccata aatcgagttg aagagaccgc ctaaagcatt
    40501 accggcaacc gtcccgattg gtcctaaagc aagaaatgtt aatggaacca tcactactaa
    40561 aacgacaagc ggaactaaaa tcatttgcag aaattgcgga atcacttttt ttacgaatgg
    40621 ctctaattta ctttgaaccc atacggctag aatgattggt atgacagaag aagtataacc
    40681 agatggtgaa agaatcactg ggatcccaaa gaaactgata gcttctcccg caccagcaac
    40741 tgctgtgata gctggataca caagtgccat agcaattgct actgctaaaa actggttggc
    40801 tttgaacttt ttagctgctg taaaagcaag catgacaggt aagaaggtaa agacaccatc
    40861 tgctgcagca aacaatattt gataagtacc gctatcagct gtcagccagc ccatcaccgt
    40921 tgccaatgat aagaatcctt tcaatacccc ggcggctgcc atcgccccta gaaaaggtgt
    40981 aaatatacta gagataatat cgatcagacg attcaaaata tttttggact cttcttttcc
    41041 atcctccgaa actgcaagac cttcctcatc cacgatcgat tgataaacat ctgctacatt
    41101 actgccaatc actacttgat actgaccgcc actttgtacg acttggatca cgtccgggtc
    41161 ttcttttaac ttttgcgtat ctgctaaaga ttcatctttt aatctgaatc gcaaccgcgt
    41221 agcacaatgt actaaacttt tgacattctt ttgtcctcct accgcttccc atacacgacg
    41281 accaactgct tgattatcca ttgttttttc cttctttctt ttttatttaa aaaataaaaa
    41341 cccagattga aaaaaacagt cacaaacatt cgtgaaccta ttttttcaat ccaggttttg
    41401 cctgccatac agtaacaatc cttatgattg gatgcttttt ttctcactta ctactctttg
    41461 aatatgaatc gttaaataaa tctgctctgc gatccccatt tcctgttttt gcgtttgtcg
    41521 aagatactca ttgatccgtt cgacacaatg aaacgctttt ggatactttc cttgaactaa
    41581 tgcgtagaga aattcatctt gctcgtcaga tccttcccct ttgagataac gctgggcaaa
    41641 aaactgcaga tgagtaatga tacgctgata attcaaagat tcttcatcga acacgatgcc
    41701 gaagaattta ctgatgatac tcagtatatc tcttaccatt gtggtagcgg tcatcgtcac
    41761 ttgcatgtct tcgtttcctt gttggctatt cacaaaatga aaggcaataa aaccggcttc
    41821 atcctcagaa agttccacac ccgtcttttg tttcacgaac aaaagagcct ctttcgctgc
    41881 ttgatattct ttcggataaa atttttttgt ttcaaataat aatggattag gcagttggat
    41941 attttctttt gctcgtgtga tcgcataatg aagatgatcg gtcaatgtca gataaatatt
    42001 aggcgaaaat tcaactttta gtttatcttc agccagttcg actacttgtt tgacccattc
    42061 gatctcctct gccggaatat cagccatcag ctgctggaat tggtttttag caaaagaatc
    42121 tcttaaaaca aattcttttt ggaccgcttc tggcgaaatc tcgtccccaa tctttttttg
    42181 aaaagctagt ccttttccca tacaaacgac ttcttccccg aatccatttt tcgaaatgac
    42241 gacattgtta ttcaaaattt tatcaatttt cattttgctt cgccctctca agaaaaataa
    42301 aaaaacctag aattcgccta ctgtttctta gctgaattct ggttttgcct gccgtacagt
    42361 aacaatccat ttcttattca aaatcatcat accatcgaat ttttatttat gcaagccttt
    42421 tcatataaaa aataaaaaaa ctggaacaca agtctatcta gaaaacaacc aaatcagaga
    42481 tgcacctctt tgcgtttctc tttttttcag caaattggtt tttccttatc gattcatatc
    42541 ctttggctgt ttttaatctg taacgactta tgtcccagta tcctaaaatg tttttgtctc
    42601 tagattgaaa gcagatctca tatcatctgt cgcatctttt atcgatgtaa cactttccag
    42661 ttctccttgt acaactagtc gcgtgacggc gtccatgtcg ccacaagtaa ttagtgtgac
    42721 aatttctttt ccctcgactt cattcagtaa ttgggtatct gtaggagcaa ctttttcttt
    42781 aaaaaatgtt ttgtatgtat acacattttc taaatctgtc aaatagatct tggcacccat
    42841 ctctaaattt tctagcggtg taaacagcaa ttcagggttc gttgcacgat ggcttgctaa
    42901 ggcataattt ccttttccca tttcttgatc tggagataat gttcctgctc cgtaaagtag
    42961 tgacgtatta tccaagcctt tgaaaaccgg taaattgatt gaaactgaag ggactgcgat
    43021 actagcaatc actggtagat ctgttcctct catttgcgac ctcatgaccc cttctgtcgt
    43081 cattggttct accgcatcaa agtcaaaact gacatcttta tcgttattct ttttcagatc
    43141 ttcttttgtt acattcgcta tagcatattt atctcctgtc tctctgacaa aataatcctt
    43201 gatctgttca ttgaaaatca aagctagtcc tactaataac aagaggaaca agaggatatt
    43261 gactagccat ctttttgctt ttcctttttt tttcattttc tctccctcca gactcatttt
    43321 actgtttttc ttttgctctt tccaacagcc gaatgacaca tttctacaac tctgtgtatt
    43381 tttttcgtac acctgcgctt ttttctacag gatatttcaa attatttttg atcaattttt
    43441 cttcaatgat ctcatctaga tccaggtgaa ggttgtctgc catcatgtat gaatagatca
    43501 atacatctgc cagttcttct ttgattcgtt ctaattgtgt ttcttttact tcttccggcg
    43561 ttttccattg aaaaagttct aacaattcag atgcttccaa agaaatagag atagccaaat
    43621 ctttttcgtt atgaaattgt cgccaattac gttcatctct aaactggttg actttttcca
    43681 tactattcat ttgcttgcct tcttccaatc acttcttact tgattaatca taccattttt
    43741 ttacataaaa aatagatgat gcttttaaaa aaactcctgt tttcttttat ttaaaataaa
    43801 tgtcatagaa aatcaataat ttaggtagcc accatgtgta tgcagtagcg tgtcttcttc
    43861 ccttgaggct ttttgttttt cgatacgttc ttcttcccaa acagacaacg ctactagaat
    43921 ctctcttaat gattttcctt cttcggtgag cgagtactct actttaggcg ggacttggtt
    43981 ataggctttt cgatggatac tttcatcttg ttctaactct cttaactgct gggtcagcat
    44041 tttttttgtg atcgtaggga tttgcttgct tctccacgcc taaaataagc gatattgctc
    44101 ttccctttat ctggtgtaag caaagcagtt agcattttga cgatcgtggg ttccgctttt
    44161 cacttcttat ctacttagta tcatgaagta tactttcgta ctaatactaa gtagcggaag
    44221 tgtcaactac tttgtttaac tacatagcaa aagaaacaga agggtgacaa cggtcatcac
    44281 gcttctgttt cttttgaata tgctgtgttg ttgtctctat ctccgtgtag actttcctca
    44341 aacttatcct ttgacagtaa gtcagtaggc tgatttgctc tttctagatg ccagatacat
    44401 ttctacaaaa aaatagtgat tctgttttga aaattcgatt tttagttctg cattttcgta
    44461 aacatccaac atttttttcg cactgtatag acctaacccg ccattttttt tagaggtttt
    44521 tcctcttttg accatctccg atagcgtcaa attcgttgga tttgccttgt tcgctatact
    44581 aaaacgtgat ccctcttttt cttccagcag attgatcgta atcggactct gatcggctac
    44641 acgatgatcg aatgcgttag aaataaaaat agataaacag cgaataaaaa caaccagatc
    44701 aatcgggatt gttttcactt cgacaggaat aactacttgg atcgggattt tctccgattc
    44761 tgctttttct agaaatttta aaaagacacc cctgacagct ggggatacaa tatttgttag
    44821 ctgttgtatt tgcggttttt caaaaatagc tgcagaatga tcttctaata tttctaaaaa
    44881 ttccaacgtt tcttttttat tttcctgaag agtaattttt aatgaaaaca gtagactttt
    44941 ataatcatgt ttgaattcct ctagatgatg gtaatattct tcatttattt gatacagttg
    45001 aagcgattcc tgatgttgtc tttcttttac ttggaaactg atcaacataa tggaaaaaaa
    45061 caaagaaaaa aaactgatga ctatcgacaa aagagataga agcagataat tagatgagcg
    45121 gaagtgaaca cttcccaata ccaagtaaat cacgccccag cttaataaaa tacaaatacc
    45181 tccaaaatag tgttcagttg gataagtaaa aagcaagttg agaaatctcg tctgtttgtc
    45241 tatacttttt actaatagat agaaaataaa tgcgataagt agtgcaaaaa aacttgctgt
    45301 tccaagatgt ctctttccta aataatccat cagatcaaaa accagaaaaa agctgagtcc
    45361 agtgatagca aaaaaaagat tactgatcaa acagctgata aacaggtttt tcgtagtaaa
    45421 ataaaaaaga aacatcaata ataagccaac taggtaagga aagctcactt tagggatagg
    45481 aagtaaaagt gtcaccacca tcaaagctat acaaccaaag ctgtttttta ctagcagttg
    45541 tttcgaaaag aataaataga tacctaaatc taaaatcaaa gtaaaggtca aataaagtgt
    45601 cactgttgcg accatcttat tcctccattg ttttgtttca aaatgtacac atattttttt
    45661 aataggagcc tgcatatgaa aaagtatttt atcatagaag ataaccagtt tcacagcgaa
    45721 tggatcatca gagaattggt caatcatcat atcgagaata tcgtgcagct cacttctatc
    45781 tctcaaatca atcagttgat ccagttgggc actattgata atcacgatgt tttctttatc
    45841 gatatcgact tgaagcaatc actcacaggt attgatgtcg ccgaacaaat acgtaaaaaa
    45901 aatgcacata gtaatattgt ttttttcacc gcttatacga attttgcagt agagatcatc
    45961 aatcggaaaa tccttccgat tggatatatc agaaaagaca ggaatttatc tgaacaaatt
    46021 cgtcaagtgc tagaacagat caattggaaa gaacagcaga tcgtaaatgt cgataaaatc
    46081 tttattgatc aaaaaggtgg aagtctcgtc ctgtatcctc gggaaatttt atatattgaa
    46141 agtatcaaag gtttgaaaaa ccaagttatg gtcaaaacaa ctacagaaga taaattagtg
    46201 aatacttctt taaaacaatt gaagacagag ttagaaaagt atgcttactt tttactttta
    46261 aaatcttact gtatcaactt atcgcaattg cagaaaattg attctgctca ttatgtgtta
    46321 gaatttttca acggtgactc cttactcgtt ggtcgaaaga tctttgaaaa gacaaaggaa
    46381 cgtttccatg acttccaaaa aactgcttcg agttgatgaa taagagctga gacgtaagca
    46441 tagcagattt cagggagtgg gccttgaatc ggctccactc cctgaaatcg ttgatatgat
    46501 tttacgcttc ctcttctgta ggagcatctg ttaacgacca tgtgaatgtt gaaacgtagt
    46561 tgtctacagc ataattggat acaggaacaa ataattccac tgattgtctc ccttgttcca
    46621 cattctctcc taatgaataa atccatgtgc caatcccttc atttgctcct gcagttacta
    46681 gatctactgc ctgatctgct gggatttcga ttccttcagc gccagttcca gaaacggtag
    46741 atggcattcc actgctatta gttgcgctat ttcgaatcac ggcgtttttg aatttcacct
    46801 ttgaaccagt tagtttattc gtatcagatg ttgtaccaat aaattctgtt cgtttgactg
    46861 ataatttcca accggcataa tttccgcttt tatccgttac ttgtacgaaa ttctgtactt
    46921 gtgtttgtgc tccagtactg tccgttccgc tttgtaatgc agcatatact gtttttgctg
    46981 tacctaactt gattgttcca aaatcaagat ctggagcttg gtcaatcgtc agtaatccgg
    47041 atgttccctg atttggttcg tcaggtgtaa aaggagtatc aggatcattt ggatcaacag
    47101 gaggaactgg aacaacgtct tcaggatttg cagcatctgg tttggtcaca gaaatcgttc
    47161 cttctgtagt ggctgagctc ttattctcag caaaaacact ttgtgtacat aataatagac
    47221 ttccagctag aacggtactt aatgcaattg tttttttcat ttct
//
LOCUS       DAJSMK010000013        44859 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.013, whole genome shotgun sequence.
ACCESSION   DAJSMK010000013 DAJSMK010000000
VERSION     DAJSMK010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.013"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            212..604
                     /locus_tag="ON488_000738"
     CDS             212..604
                     /locus_tag="ON488_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCR3230953.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="ON488_000739"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="ON488_000739"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HCR3230954.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="ON488_000740"
     CDS             3165..4775
                     /locus_tag="ON488_000740"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HCR3230955.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="ON488_000741"
     CDS             5067..5936
                     /locus_tag="ON488_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HCR3230956.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="ON488_000742"
     CDS             6101..7372
                     /locus_tag="ON488_000742"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCR3230957.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="ON488_000743"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="ON488_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HCR3230958.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="ON488_000744"
     CDS             8763..9026
                     /locus_tag="ON488_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HCR3230959.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="ON488_000745"
     CDS             9471..9920
                     /locus_tag="ON488_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR3230960.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="ON488_000746"
     CDS             9977..11395
                     /locus_tag="ON488_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3230961.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="ON488_000747"
     CDS             11395..12255
                     /locus_tag="ON488_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HCR3230962.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="ON488_000748"
     CDS             12429..13202
                     /locus_tag="ON488_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR3230963.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="ON488_000749"
     CDS             13349..13714
                     /locus_tag="ON488_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HCR3230964.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="ON488_000750"
     CDS             complement(13862..15070)
                     /locus_tag="ON488_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3230965.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="ON488_000751"
     CDS             complement(15089..15367)
                     /locus_tag="ON488_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230966.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="ON488_000752"
     CDS             15521..16216
                     /locus_tag="ON488_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCR3230967.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="ON488_000753"
     CDS             complement(16658..17455)
                     /locus_tag="ON488_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HCR3230968.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="ON488_000754"
     CDS             complement(17452..18636)
                     /locus_tag="ON488_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCR3230969.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="ON488_000755"
     CDS             complement(18661..19908)
                     /locus_tag="ON488_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCR3230970.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="ON488_000756"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="ON488_000756"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HCR3230971.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="ON488_000757"
     CDS             21888..22202
                     /locus_tag="ON488_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HCR3230972.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="ON488_000758"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="ON488_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HCR3230973.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="ON488_000759"
     CDS             22887..23531
                     /locus_tag="ON488_000759"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HCR3230974.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="ON488_000760"
     CDS             23546..23875
                     /locus_tag="ON488_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HCR3230975.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="ON488_000761"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="ON488_000761"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HCR3230976.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="ON488_000762"
     CDS             24863..25687
                     /locus_tag="ON488_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HCR3230977.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="ON488_000763"
     CDS             25680..26027
                     /locus_tag="ON488_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HCR3230978.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="ON488_000764"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="ON488_000764"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HCR3230979.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="ON488_000765"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="ON488_000765"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HCR3230980.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ON488_000766"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="ON488_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HCR3230981.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ON488_000767"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="ON488_000767"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HCR3230982.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="ON488_000768"
     CDS             31657..32451
                     /locus_tag="ON488_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3230983.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="ON488_000769"
     CDS             32441..34483
                     /locus_tag="ON488_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3230984.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="ON488_000770"
     CDS             34764..34913
                     /locus_tag="ON488_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HCR3230985.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="ON488_000771"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="ON488_000771"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HCR3230986.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="ON488_000772"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="ON488_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HCR3230987.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="ON488_000773"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="ON488_000773"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HCR3230988.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="ON488_000774"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="ON488_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HCR3230989.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKDWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="ON488_000775"
     CDS             39330..40412
                     /locus_tag="ON488_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HCR3230990.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="ON488_000776"
     CDS             40412..41215
                     /locus_tag="ON488_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCR3230991.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="ON488_000777"
     CDS             41285..42025
                     /locus_tag="ON488_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR3230992.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="ON488_000778"
     CDS             42036..43040
                     /locus_tag="ON488_000778"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HCR3230993.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44782)
                     /locus_tag="ON488_000779"
     CDS             complement(43085..44782)
                     /locus_tag="ON488_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3230994.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14420 a         7827 c         9342 g        13270 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa agattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataa
//
LOCUS       DAJSMK010000014        43514 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.014, whole genome shotgun sequence.
ACCESSION   DAJSMK010000014 DAJSMK010000000
VERSION     DAJSMK010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.014"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            69..3371
                     /locus_tag="ON488_000780"
     CDS             69..3371
                     /locus_tag="ON488_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HCR3230995.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEVPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESCTYT
                     NAQEGFALMVRDAVPKDHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKDLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIKLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSFLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTVSKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNESPNESPNESPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLI
                     GVVVYVMKQRKK"
     gene            complement(3911..5818)
                     /locus_tag="ON488_000781"
     CDS             complement(3911..5818)
                     /locus_tag="ON488_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HCR3230996.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNEQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIQYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5948..6823
                     /locus_tag="ON488_000782"
     CDS             5948..6823
                     /locus_tag="ON488_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HCR3230997.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     ALIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKEWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6903..7877
                     /locus_tag="ON488_000783"
     CDS             6903..7877
                     /locus_tag="ON488_000783"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCR3230998.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8057..9202
                     /locus_tag="ON488_000784"
     CDS             8057..9202
                     /locus_tag="ON488_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCR3230999.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSCQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLEQLVRAVKK"
     gene            9339..9683
                     /locus_tag="ON488_000785"
     CDS             9339..9683
                     /locus_tag="ON488_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HCR3231000.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9954..11227
                     /gene="efmA"
                     /locus_tag="ON488_000786"
                     /pseudo
     CDS             9954..11227
                     /gene="efmA"
                     /locus_tag="ON488_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
     gene            complement(11377..11976)
                     /locus_tag="ON488_000787"
     CDS             complement(11377..11976)
                     /locus_tag="ON488_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCR3231001.1"
                     /translation="MNYFTSDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12380..13501
                     /gene="mnmA"
                     /locus_tag="ON488_000788"
     CDS             12380..13501
                     /gene="mnmA"
                     /locus_tag="ON488_000788"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HCR3231002.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNHAEVVFD
                     EPVRAITPGQAVVFYDEMECLGGGLIDHAYQETKVLQYV"
     gene            13747..15168
                     /gene="arcD"
                     /locus_tag="ON488_000789"
     CDS             13747..15168
                     /gene="arcD"
                     /locus_tag="ON488_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HCR3231003.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFAIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVAFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15182..16300
                     /locus_tag="ON488_000790"
     CDS             15182..16300
                     /locus_tag="ON488_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HCR3231004.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SEFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILER
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16360..17652)
                     /locus_tag="ON488_000791"
     CDS             complement(16360..17652)
                     /locus_tag="ON488_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCR3231005.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLAHQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNAAALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLMGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSISSGHSPSHRQ"
     gene            17784..18362
                     /locus_tag="ON488_000792"
     CDS             17784..18362
                     /locus_tag="ON488_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3231006.1"
                     /translation="MRGNMKMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLEGIHETNQIILQIFEAFQLTKEEKVHRSRELCSMIHGYL
                     SLRFLGYFTKESTIDPEDSYFWMINDFIATLP"
     gene            18491..18868
                     /locus_tag="ON488_000793"
     CDS             18491..18868
                     /locus_tag="ON488_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HCR3231007.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEAEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESGKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18801..20873
                     /locus_tag="ON488_000794"
     CDS             18801..20873
                     /locus_tag="ON488_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCR3231008.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEEQKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKEMRINPDF
                     TIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKMLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21084..22031)
                     /locus_tag="ON488_000795"
     CDS             complement(21084..22031)
                     /locus_tag="ON488_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR3231009.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDVDSVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22276..22740
                     /locus_tag="ON488_000796"
     CDS             22276..22740
                     /locus_tag="ON488_000796"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HCR3231010.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQQILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(22802..23845)
                     /locus_tag="ON488_000797"
     CDS             complement(22802..23845)
                     /locus_tag="ON488_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HCR3231011.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGIKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(24345..25310)
                     /locus_tag="ON488_000798"
     CDS             complement(24345..25310)
                     /locus_tag="ON488_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HCR3231012.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25544..26389
                     /locus_tag="ON488_000799"
     CDS             25544..26389
                     /locus_tag="ON488_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR3231013.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YPLPQLMKHLIKRFPKVHFEIEIANSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            26580..27767
                     /locus_tag="ON488_000800"
     CDS             26580..27767
                     /locus_tag="ON488_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCR3231014.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYFYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVVGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            27773..28129
                     /locus_tag="ON488_000801"
     CDS             27773..28129
                     /locus_tag="ON488_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HCR3231015.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            28131..28469
                     /locus_tag="ON488_000802"
     CDS             28131..28469
                     /locus_tag="ON488_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HCR3231016.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     misc_binding    28545..28801
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            28864..29898
                     /locus_tag="ON488_000803"
     CDS             28864..29898
                     /locus_tag="ON488_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3231017.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            29891..30577
                     /locus_tag="ON488_000804"
     CDS             29891..30577
                     /locus_tag="ON488_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231018.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            30601..31449
                     /locus_tag="ON488_000805"
     CDS             30601..31449
                     /locus_tag="ON488_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HCR3231019.1"
                     /translation="MKKKIFGLAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDNIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            31646..32419
                     /gene="sufC"
                     /locus_tag="ON488_000806"
     CDS             31646..32419
                     /gene="sufC"
                     /locus_tag="ON488_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HCR3231020.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFNGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            32432..33718
                     /gene="sufD"
                     /locus_tag="ON488_000807"
     CDS             32432..33718
                     /gene="sufD"
                     /locus_tag="ON488_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HCR3231021.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSTVDQLGKNITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            33715..34950
                     /locus_tag="ON488_000808"
     CDS             33715..34950
                     /locus_tag="ON488_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCR3231022.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAH
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     SFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVINPVQELAELVHENGGVIVVDGAQSAPHRAIDVQALDCDF
                     FAFSGHKMCGPTGIGALYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQELGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            34937..35407
                     /locus_tag="ON488_000809"
     CDS             34937..35407
                     /locus_tag="ON488_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HCR3231023.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            35412..36803
                     /gene="sufB"
                     /locus_tag="ON488_000810"
     CDS             35412..36803
                     /gene="sufB"
                     /locus_tag="ON488_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HCR3231024.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(36898..38040)
                     /locus_tag="ON488_000811"
     CDS             complement(36898..38040)
                     /locus_tag="ON488_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR3231025.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(38079..38813)
                     /locus_tag="ON488_000812"
     CDS             complement(38079..38813)
                     /locus_tag="ON488_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3231026.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            39045..39320
                     /locus_tag="ON488_000813"
     CDS             39045..39320
                     /locus_tag="ON488_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231027.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            39418..41415
                     /locus_tag="ON488_000814"
     CDS             39418..41415
                     /locus_tag="ON488_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231028.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSVEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(41491..41826)
                     /locus_tag="ON488_000815"
     CDS             complement(41491..41826)
                     /locus_tag="ON488_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3231029.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            41953..42168
                     /locus_tag="ON488_000816"
     CDS             41953..42168
                     /locus_tag="ON488_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3231030.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            42205..42567
                     /locus_tag="ON488_000817"
     CDS             42205..42567
                     /locus_tag="ON488_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HCR3231031.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            42613..42939
                     /locus_tag="ON488_000818"
     CDS             42613..42939
                     /locus_tag="ON488_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231032.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
BASE COUNT        14261 a         7763 c         9106 g        12384 t
ORIGIN      
        1 tgacagtaaa aataaattag gtaatacttt aagtaaacgt tttctaattt gttgcgggag
       61 gaatacactt gttaaaaaaa cgtataaaat acagtgcgct aatgatgaat ctccttatgc
      121 tcagtacccc ggttttaatt tctgtcgttg aagttgctgc taacgaacaa cagtctgtga
      181 acgaagaaaa tgcacacgtg aacattgaag ggatgtcaac aatggaggaa gtaccaagaa
      241 ctagtgaaga tatggatacg gaagaaggaa atgatcctat gatgaaagaa tcagaaaatg
      301 aaaagacaaa aaagcaatct gaagaagcaa atgaagagtg gaaaggggtt gttttcggag
      361 aaagcacaag tgctagtagg tatgccattg aaccattaga agacggcgtg cggctctctt
      421 ccacgaataa cggcggaaaa ttccagtcaa gcggatcaga tggaatgacc tattattatc
      481 aagcaatccc caaagacatc aactttagga tgcgggcgac gatcgaaata gaatcttgca
      541 cctatacgaa tgcccaagaa ggatttgctt taatggtaag agacgcagta ccaaaagatc
      601 atttgtttgg gcaggcattt tattcaaatt catttgccat actaggcagt cggatcgaat
      661 atgtctggga ctcggataga caagaagtgg tcaacacgag cggcagcaaa tatacgatgc
      721 gacttggatt ggggacacgg gcaatcacag gaatatcatc tgaagatccg caagctgcgc
      781 cagctcctgg gagtgtctca gtggaaacaa cacctttaga gacttcagca gggttcttgg
      841 aaaaagaaac aggttcttat aatatattcg gaaacggtca tgggaatctg tttccggcca
      901 cgaactcgat tactaaactg gacgtagaga tgaaaaaaac gaatactggt ttagaggcat
      961 attattacga tcctgaaaca ggagaagaaa tggcttctga catcatgtat gactgggaaa
     1021 aattatacgc ttcagatgaa tcggttattt atgcaggatt tgctgcagca aggaatatga
     1081 cgatcaaggt agaaggaatc gaagttgctt actcagatcc tgcgacagat cctcctgggc
     1141 aagaaagacc tactcgcttg attgatccga tttacactgt gacctctagt aatcattcag
     1201 gaaaccaaga tcatactatg tcctttagag caaatgctga cggattattg acaattaaaa
     1261 ataaagcaac aggagaggtg cttaagaacg caaaagactt ggctatcact gcgaatcggg
     1321 aatttgatta tcagacaaaa ctgatggaag gaacgaacga atttactttc agttttacgc
     1381 cagataaaaa ctatccgcca gaagaatacg tagagatgac tagttatgaa acaaaagaga
     1441 ttcttcatac agtggactac cgtaaaccta aatattcgac agtttatgta acaccagaag
     1501 ggtcagatgc aggaaacgga agcagacaaa atccattatc tctgacacaa gcattgagat
     1561 acgcatatgc tgggcagaca atcgtcatgg cgcctggaac ttattccttc gaaagaggat
     1621 tgacgattcc caaaggcgtt aacgggacaa gagaaaaccc gattaagttg attgcagaga
     1681 aaaatccaga aaacaagcgt cctgtacttg attttaaagg aactggaaat gggatgacac
     1741 tgttcagtca ctactggggt ttacgagggt ttgacattac aaatagtgca gctatgcaaa
     1801 aaggattaca gatttctgga aatcataatt tgatcgaaga gattcatgct tatcggaatg
     1861 gaaatacagg aatccaaatc agcggtagct caaatgatcc tttcgaagca tggcccgcgc
     1921 ataacttagt caagaactgt acatcttttg aaaatgccga tccaggattt gaagatgccg
     1981 atggatttgc ggccaaactg acaataggag aaggaaatgt atttgacggt tgtatcgcgt
     2041 atcataatgc agatgacggt tgggaccttt ttgctaaaaa tgaaacaggt tcgatcggaa
     2101 aagtaatcat caaaaactca gttgcttatc gaaacggctg ggtaccggga attgagggag
     2161 aaggtaacgg taatggattc aaaatgggcg gttctttttt aacgggccct catgaattga
     2221 tcaatagttt gtctttcgaa aatcttgcga aaggaatcga ttccaatagc ggaacagata
     2281 ttatcgtcaa tagcagtaca agttttaata acggttcata taatgtggct ctttatacct
     2341 cttcagcagg aaacacagac taccatgctt ctggtatctt atctttccga acagagaatc
     2401 ttgagatgag agagcagatc cgcccattga atcaaaacga agatcaaatc taccactcgt
     2461 tgaactacta ttggaatgaa cgagagaaac aatcagaaaa tactcttgga cataccgtat
     2521 caaaagattg gatcgagtct ctaaatacat gttcgaaaga aggtcagcag cctgttacgc
     2581 gctatgaaaa tggaagtatc catgttcatg gactgatgca gattaaaccg gggaatcgtc
     2641 aaacagaaaa ggaaagagtg gatggtcttc cattatctgt aggtgctatt tttgacggag
     2701 aaacctcgcc atcttcggaa tatccagagt atgcaatcgt acaagaacca aatcagacaa
     2761 aaccaaatga acaaaataat ccgattatta tacaagaagc aaatggtgtg gcggagaatg
     2821 cagaaggaaa tatcattgaa ctgaagcctt ttacagtttt tgtgtcaact ttcacaccaa
     2881 atcaaggaac gcctgtcttt gaagatatgc gttatttccc agaaaagatc caaatcgttg
     2941 aaacacagtc aagtgctcaa ttttctaatc ataccgctat tttttcagca ccttcaaaag
     3001 gagaatatac gctagaagtc acttatcgtt cggaaatatt tgatggggaa aaatggtctg
     3061 ctcatacaga atctgttacc cagcaaaaag cgatcactgt gcgagaaact gccgatgtgc
     3121 ccccgggaaa tgacaaacca gaaagagaaa atccaggaaa tgaatcacca aatgaatcac
     3181 caaatgaatc accaaatgaa tcaccaaatg gaaaaccttc tcatccggac aggacagcaa
     3241 aagaaagtga aaaaaatggc actcaaggac tcccaaaaac gggagaattt aataacccgt
     3301 tgctagcatt agctggagga attttgttaa tcggtgtagt tgtttatgtc atgaaacagc
     3361 gaaaaaaata agtggaattt ctccttttat gatgtaaaac aattgactga ggaaagtaaa
     3421 aatagaagga aatgagacca atagatgtct cacttccttc tatcttttta tagatgaggt
     3481 tctccttgct gcttttgatt ggctgttctt attacttgat gcaggacagc tttttcacaa
     3541 cctctccact aaacggtgtt caatcagctg accctcggta ttagctcaac aaacggcaaa
     3601 atatgaggaa ctatttttcc gttttttctc taatactcag gtcaggacgc tgatttcaca
     3661 acctctcgat aaacggtgtt caaaagccag tttctcagta gtaagtcaaa tttatgcaaa
     3721 aatgtggaaa gctattttca caaaattttt cttactactt gaaactaagc ggctttttca
     3781 caacctctga tacatggtat tccagaagta acttcttcga aaaataagcc gaaatgtcac
     3841 aaaaatttga gaagcaattt tccccaattc cttcttattt cttgaagctg accacttctg
     3901 gcacaacctc ttaccagatt cgcactcttt tttctggcgc tagatacata gcgtcttgtt
     3961 ccgtgatacc aaatgtttca tagaattcgt caaggttttt tggttgcacg tttgctcgga
     4021 gtttagcagg ggcatggaca tcgatttgca gtaaaagttg ttggtattct ttttttgctt
     4081 ttgtacgcca aatcgttgcc caattgacaa agaattcctc gatagaaaga tctgattccg
     4141 tttttgctgc ttccaatgca cagcttagac cgcctgcatc agcaatattt tccgaaacgg
     4201 ttaattttcc gtttactttt ccgtcagcaa aaggcagacc atcgaattct tcgatcattg
     4261 cttgtgcttt gttttgaaat tgtgtaagat cttcttctgt ccaccagttg ttcaagttgc
     4321 catattcgtc aaataaagcg ccgttattat caaatgcatg ggaaatctca tgagcgataa
     4381 cagctccgat tccaccataa ttagcagagc ttgattgttc tagactgtaa aatggtgctt
     4441 gaaggatcgc tgccggaaag acgatcacat tccgaaatgg atgataataa gcattgaccg
     4501 tgtcagcact catttcccat tctgaacgat ccactggttt gttccatttg ctgaaacgat
     4561 cttttaatgt gagtttgctg aaaacaagag tatttgaaag caaagtacca ccctgatctg
     4621 caggtactgt tttgaactgg tcgaataatg ctgggatctt atcggggtag cctacttgga
     4681 tacctaagtt atttaatttt atgacggctt tttcttttgt tgcatcccca agccagtcat
     4741 tttcttctag acgtttttta taaacggcga tcattttttt caccatttgt tctacgtctt
     4801 ttttagcagc ttcgccaaaa tatttttttc cgtagtaatc gccaactact tgatcgaatt
     4861 gtccagaggc aaggtaatac gctgcttttt tctgaggcat tgcttcgtct gttccagaca
     4921 atacgcgaga atagattccg ctgacttggc ggaattcttc tgatagataa ccactaagag
     4981 aacgtactgt tttaatgatc atccagcttt tgaataacgg aaaatgagct tctgtcagga
     5041 tgtcattcaa atgatcgaag tacactggat cagttacgat cactttatct ggagttgtcc
     5101 caatcaaacc cgtgacaagt tttttcaagt ccagtttatc tgtgtattga ataaatgtat
     5161 caaaagattg cggattatac attttgctgt aatctgcgtt ttcttctgca ctttttacat
     5221 gaggagcaat caatttatca aattgcactg cttgttccgt gattgcttct gcctgacttt
     5281 tttctttgcc ggcaagctct aataactgaa cagccatatc aaagaaaacg cctattagtt
     5341 gtgcaccgtt gggatggtct gatgcataat acgtcttatc tggaaggaat aaagaaggcg
     5401 gataagcaaa gaaggcgttc gtttgcgcat tcttcatatc tgcatctaca tccagattaa
     5461 atggcaatgg taatgtatcc aacagccatt ctggaaattg ctcattcaat tcgtcgaaag
     5521 actgcaatga ttcaactttt tcgattatag gttgaagtgg ttgagcatgc aactcatttc
     5581 ttcggtcata atcgtttgcc agttgataat atgcaaggaa atgtttcatt ttttctgaag
     5641 acactttttc tggatgggca agcagatcgt ctgtttctcc catcaaaagt tggtcgatcc
     5701 cgtcaactaa atcttggaaa ccgcctgtag ctggtttatc tgcagggatt tttgctgttt
     5761 tttgccattc ttcattgact gcttcataga aatcttgttt caatcgttct ttgttcattc
     5821 atcgatcgct ccttttttgt ttcgtgtgcc cattatctta caaaatgaag gaattaacaa
     5881 atagaacata aaaaattgaa aattcgaaca atcaaactga tttgtttttt tcaatccttc
     5941 acttataatg aaaaaaagga ggcgatccca actgaatcaa gtagtggata aacctttata
     6001 tttcaaagta gataaaaaaa ttaaaaaatt agccagcact cagcagctgc agtcaagaaa
     6061 aagtaaattg ctttttttag ctctggtttt tgaagatcaa agttatgtga ttatcgatca
     6121 atcaggacat ccggtagaat attctccagc aaaatatact tatcaagagg gtctttcttg
     6181 taaaaaatgg aagctgatca atgaagagcc aatcgagtta tctagatgga tcaacagaaa
     6241 agaagatatt cccgctttga tcgaagaaaa aaggtcagga aaggaactcg caaattgctg
     6301 ggtgggattg ccagaagaac gttttttgag gtataagaaa tgggctaccc cctcaggcta
     6361 tctttgtggt acttacgcgg cagcagttct ccttgcctat tatcaagact atcgtaagga
     6421 gtggatgctt ccaaatgaga ttcgcaagaa aaatacggct gattcgttgg ttttgacgaa
     6481 ggcattgcgt agccagatcc aaccactagg acttcctacg attccttttc aggttagtac
     6541 agggatttct agttttttaa agaagaatgg caatcatgag cgtgcacgag caactcttct
     6601 aggttcatgg cagcgagcta caaaacgtat acgtgaaggc aaacctgtga tgattggtat
     6661 tttgaaagta cttggcagta catatggcaa tcattgggtg acagcgtacg cttattttga
     6721 aactgaaaca ggagaacgtt attacaaagt acacgacaac tggggcgatt atcataaagt
     6781 cattcctgcc agttggagta acggaacagt ttcacttcct taagaatttg ctgaaattaa
     6841 cagaaaatct tggaaaaata tgttaaacta tcgaagaata gagaagtttt ggggaggact
     6901 acatgagtaa taagtatcag gatgacacgt tgaagatttt tagtttgaat ggcaaccgtc
     6961 cattagctga aaaaatcgcg aaagtgttcg gaacagaatt aggtaaaagc gtcgtgaagc
     7021 aatttagtga tggcgagatt tccatcaata tcgaagaaag tattcgaggg gatcatgtgt
     7081 atatcgttca atcaacgaat gcacctgtca atgactacta tatggaacta ctgatcatga
     7141 tcgatgcaat gaagcgagca agtgcgaaaa cgatcaatgt cgtattgcct tactatgggt
     7201 atgctaggca agaccgcacg gcgaaacctc atgaaccgat cactgcgaaa ttgatcgcta
     7261 acttgatcga agaagcaggg gcaactcgag tactgacttt agatctgcac acggttcaag
     7321 tacaaggatt ctttgatatt cctgtagata atttatttac gatgccgttg tttgctcatt
     7381 attaccgtca attaggtctg acgggagatg acatcgtagt tgtttcgcca aaaaacagcg
     7441 gtgttcagcg tgcacgtagt ctttcagaat atttgaacag cacattagcc atcgtagatc
     7501 atgcagatga tgcttcaact gagggtggtt atgtgatcgg tgatgttcaa ggaaagacat
     7561 gtatcatggt agatgatatc ttgaacacag gagcaacgct tgcacgagca gcaaatgtat
     7621 taaaagaaaa cggcgcaaaa gaagtatatg cctgtgcgtc acatggatta ttgtccgatc
     7681 atgcgaaaag tattttagac aatgcaccaa tcaaagatat ttgtatcact gattctgttt
     7741 tcacagaaga aaatcgtcat ccagaaaact taacaatcgt tacatgttca gaattaatgg
     7801 gagaagcggt caaacgcatc catgaaaata caccgatgag tccgttattc cgtctggaag
     7861 aaaaagaatt cgaataaaca aaaaaaagag ggaaagaagt tgtgacacaa gtgagcagct
     7921 tcaaggagct gcgacaagac ttttgtcata gctccttttt tctatgccca tgaaacgtcc
     7981 tctagacaaa aatgagctct tctttggttt gttcgctatt ttatgctaga atgtgcctag
     8041 caataatttg gaagggatga atgaagtgaa aactatttat ctggatcatg cggcaactac
     8101 ccccatgcat ccacaagtaa ttgaagcgat gacggcaatc atgcaagaca cgtttggaaa
     8161 tccttcaagc atacatggat ttggtcgcca cgcgcatgaa aaattggaaa cagcaagaca
     8221 aatcattgca gacagtctgc aagcaaaacc tcacgagatc atctttaaca gtgggggaac
     8281 agaaggggat aatacagcta tcttagaaac agcgttctcg tgtcaaaaag aaggcagaca
     8341 tctaatcact acagctatcg aacatcctgc tgttcttaat accatgaaat atttagagac
     8401 aaaggggttt gacgttacat atctgcctgt agatgaaaaa gggaatctgt cgatcgaaga
     8461 ggtcaaaaaa gcgttacgag aagatacgat cttggtctct gtgatgtatg ggaacaatga
     8521 gatcggaaat ttgatgccaa tcaaagaaat cggtgaactt ttagcggatc atccagctta
     8581 tttccataca gatgcggtac aagcgtacgg aaaccaaacg atccatccag aagaattagg
     8641 aatcgattta ttaagtatct ctgctcataa aatcaatggg ccaaaaggcg tcggtttctt
     8701 atataaacga gacggagtaa atatccctgc attgctttta ggcggggagc aggaagaaaa
     8761 gcggcgtgca ggtacagaaa atttagcagg gatctggggt atggcaaaag cagttgaact
     8821 gctgtcacct gaagaacgtg aagcacgtaa caacaaatat aaaggattcc agcaattgat
     8881 tcttgataca ttagaagcaa acgaaatccc ttatcaagta aatggtgatt taacgaataa
     8941 actccctcat gtgttgaatc ttcgcttaat tggcgaagca aatgatttgc tactgatgaa
     9001 gcttgatctt aatggggtcg ctatttctac tggttcagct tgtacagcag gtaatatcga
     9061 gccttcacac gtattagaag caatgtatgg agaagataca ccgatactaa aagaatccat
     9121 ccgtatcagc tttggtttgg gaaataccga agacgacatc cagtatttcc ttgaacaatt
     9181 agttcgtgct gtcaaaaaat aactagtgaa gtcattctta tatgaacaga tgtctgagag
     9241 aacgccttca ttttttaggg aacttaactg aaaaacctag taaaaatcag gataaacttt
     9301 tataataaag agaaactaat tttatcgagg tgaaaatcat ggcatttgaa acaacagcaa
     9361 cggtactggg cgcaccaatt agctatcgtt tgcatcctga tgcaaaaaga tatacattgc
     9421 gcgataatgg atttacagaa acaaacggag gcaattatca attgatccga ccattagatg
     9481 ccacgccgca aagcaaagaa ggattcaaat taaaaatcac tgtatcaaaa gatattcaaa
     9541 cattgaaaat gtcgatcact acagcaaatg gattgaaagc agtcaatatt ttcaaagatc
     9601 caaaacagaa aatgagccaa gataaatttt attttctgat ggatgggatg attagccgtg
     9661 ggttattcga aaaagtcgaa tgatctgtgg atataaaaag acaactagtt ttgaaacggc
     9721 ctattgttag atgactaact ttgtaaggac aacgcaaatt agttgtcttt tttattttta
     9781 aatttaacac atgttgttat ttttaatatt ttgctgattt attgtttcta agtaaagaaa
     9841 tttaaattga aacgattgtt atttagggaa aaaggtattt tttgaaaaaa gaatcccgta
     9901 taatgattgt tgtgcaaacg ctatacaaaa tgaaaaagaa aagagggatg tttatggaaa
     9961 atgaacagtc ggtcgtttta acgaattgga agagaaatta tttgttcttt ttatcgggac
    10021 agtttttgtc aggaatcact agtatggtcg tccaatatgc gatcatctgg tatttgacaa
    10081 gagaaaccgg ttcggcgaca attttgagtt ttgctacttt actaggaatg attcccatgg
    10141 ttttactaag cccatttgta gaaccgctag tggatcgctg ggataaaaaa gctcctttga
    10201 ttgtcacgga tattattgta gcgattttcg cgcttatttt agcagtagtc ggaacgattt
    10261 cagaatcctt cccgatttgg ctagtttttg tgtctttgtt tatgcgttcg gtcgcacaaa
    10321 cattccaaat gccaacgatc agtcgattat gccgacaatc gttccatctt ctcacataac
    10381 aaggacgaat ggacagttag gaatggtcca atcagcgaat ttcatcattg cgccagctct
    10441 aggtgcggct ttgttttcag tcgttcctgt caattacctt attttattag atgtattggg
    10501 ggcagttttt ggtgtcggct tattgatttt tgtgaagatc ccaaaagttt ctcctgaaat
    10561 attggaagtt ccgcttacta tttttaaaga tgcaaaattt gggctgcagc aattgatgga
    10621 taacaaaggg ttatggtaca taacgatcaa tggtgcattt gtgatgctgt tgttcatgcc
    10681 agcaatcagt ctgtatccat tgatgacgct agattacttt ggtggttccg ttggacaggc
    10741 gggagcagtg gaagtagtct acgcagtcgg aatgctctta ggcggtgcac tgatcagttt
    10801 tataggaaca tggaaagacc gaatgaaacc tattattata gcctacatca ttatgggcct
    10861 gacgatcggt gcaagcggat tgggtccaaa cgatagtcaa gggttcttgt actttcttat
    10921 cttgaatgca ggagcaggtt gtgcaacgcc atatttcaat acactgctga tggcaatgat
    10981 ccagcagagt tatgaatcga atgttttagg tcgtgtctta gggaacttca actctttgat
    11041 gaacctggca ggtccaattg gattattatt tgcaggacca ttagctgatc gtttaggggt
    11101 agaaaaaatg ttcttgtttt ctggaatcgg gattttatta tgcggaatcg ttttattttt
    11161 aacgtcagct gctcgaaatt atgataaaga attacagaaa aaattggtaa aagaacacca
    11221 tgagtaaaaa gacgaatagt atggaatgga gttgtgacag aagtcttgtt acaactccat
    11281 ttctgatcct aatgttcctg tggcaataag cctactcaaa tgaaaaatat gagtaattat
    11341 ctttatttgt ttaatacttg atatagggca gttttttcac gacctatcgt acttcctctt
    11401 tgcttcatag atttctttga tttgttgctc agataacgga gtgccaaatg gtagtttttc
    11461 ctttaagagt tccctttccg gtgcgtctac gcctacattg acatcgttct cgataggtac
    11521 gctgtaatga tggatatgtc catgaagatt gcggatagtg tcgttaggcc cgagcaacat
    11581 cggataatga gtcaagtaat attgttgatg gtcgaattta acgatggcac ctacatcata
    11641 aaaataaaat ttgggacttc cgtcagtaag cctaggatca tttttttcta aataacggaa
    11701 aaaagcgcga ctgtcatggt tccctttgat caagtggatt gttccttgca gttgagtgac
    11761 cagttccaaa atttctgcat ttgctttttc atattgcgga tgcatagcaa ggtcgcctag
    11821 atgataaaca tggtcggttt cttttattac tgcattccag ctagtgatca actgttggtt
    11881 catttcatcc acatttgcaa agagccgcgg agcaaagtcg ttttttccta ataagcgttc
    11941 atggaaaaag tgcatatcac tggtaaagta attcatgtat cttttgcctc ccttttttct
    12001 tagagtaaac aaaatcactt atctgagcaa ctcataacat ctaaaaagaa aaggttgtaa
    12061 atgagacgtg tagctttaag cgataagaag caattttgaa aaatagtttt tcacaattta
    12121 taaaattatt ccttattgcc gaaaggctgg ccctttttat gagtatgcca attttttata
    12181 tcgaatgctc aaaagatgag tgattttttg gttgactatc atgtttgtgt actgaatagg
    12241 tccagtagaa cagtattttt acgacttgat aattaaggga tgaaattttc agaaatatga
    12301 cgtataatgt aaaatactga aaagttgcga ccttcaactc gtagatgttt cagaatctaa
    12361 ttgaaatgat ggtgatatca tgacagacaa cagcaaaaca cgcgttgtcg tagggatgag
    12421 cggcggtgtc gactcatctg taacagcact tttgttaaag gaacaaggat acgacgtgat
    12481 cggaatattc atgaaaaatt gggatgacac ggacgaaaac ggtgtatgca cggccacgga
    12541 agattataag gatgtagcga aagtagctgc tcaaatcggg attccttatt attctgtgaa
    12601 ttttgaaaaa gaatattggg atcgtgtatt tgaatatttc ctagccgaat accgcgcagg
    12661 acgtacacct aacccagacg tgatgtgcaa caaagaaatc aaattcaaag cattcttgga
    12721 ttatgcaatg gatcttggcg ccgattatgt agctactgga cattatgcgc aagtcactcg
    12781 cgatgaaaac ggcgtggtcc acatgcttcg tggagtagac aataataaag atcaaactta
    12841 cttccttagc caattatcac aagaacagct ttcaaaaacg atgttccctc taggcggcat
    12901 ggaaaaatca gaagtacggg caattgctga acgcgcaggc cttgcgactg ctaagaaaaa
    12961 agattcaacg ggaatctgtt ttattggtga aaagaacttc aaacaatttt tgagcaacta
    13021 tctgccagca aaaaaaggaa atatggtcac tcttgatggt gaagtcaaag ggcaacatgc
    13081 tggcttgatg tattatacga ttggtcaacg tcaaggacta gggatcggtg gcggaggaga
    13141 ttcgcaagaa ccctggtttg ttgtaggaaa agatctagcg acaaacacat tatatgtggg
    13201 gcaagggttc catcatcctg cattgtatgc cacaagcttg gatgcaagtg aaatccactt
    13261 tacgacgaat gaaccaatgc caaaagaatt caagtgtaca gcgaaattcc gttatcgtca
    13321 gcaagacgtt cctgtgacag ttcgcttatt ggatgataat catgcagaag tcgtattcga
    13381 cgaacctgta cgtgcaatca ctcctggaca agcagttgta ttttatgatg aaatggaatg
    13441 tctgggtggt ggtttgatcg accacgcata tcaagaaaca aaagttttac aatacgttta
    13501 agcgatatta aatgaatcaa aacagctatg gctaacaaaa gaaacacctt ttcttttgga
    13561 tagcatagct gtttttttgc aataaaatta atttttattc attttatact tgaaatactt
    13621 gtgtaaaaag ttcataatat ccaataatat gaataaagtt gctttttgtt aagcaagagc
    13681 agttgcaaaa tagaaggaaa tcttttgcaa gtgatttgtt caattttata agtgagggtg
    13741 atggaaatgg aaaagaaatc aacgggtatt agcaaatggg gactggttgc tctggttgtc
    13801 agttcgtcaa tcggaagcgg tgtgtttggg atcacaagtg atctggctag ttctgcagct
    13861 ccagggccag cgatcctttc atggataatc gttgggattg gtattttagc tttggtatta
    13921 tcgctgaatc atttaggaga aaaacgtcca gatctagatg gtggtatttt cggttacgcg
    13981 gaagcttcat ttggtaaatt aggtggcttc atcagtggtt ggggttactg gttgtctgcg
    14041 tggctgggaa atgttgcttt tgcaacgatg ctgatgagcg ccatgggaga atttttcgcg
    14101 atattcaaag gtggacaaaa tgttccttct attttatttg caagtatttt tatttggggt
    14161 ctgactttat tagtaaacaa tggagttgaa ggagcgagcg tcatcaatac aatcgtgacg
    14221 atctgtaaat tagtgccatt attcctattt ttaatatttg tatttatcgc atttaaagtg
    14281 aatatattca ctgctgattt ttggggtaac gtatctgata atctagtgaa tggaacaggg
    14341 cagcaaggaa cgatctggtt gcagattaaa ggttgtttga tggttatgat gtgggtcttt
    14401 gtagggatcg aaggcgcaag tgttttagcc aaccgcgcga agaaacgttc agaagcccag
    14461 caagcatcga tcattggtct gctttgttta ttgtttatct atatccttgc ttcgatcttg
    14521 ccatacggcg tcttatctca agaagagtta gcaactattt cacaacctgc tatggcaaat
    14581 attttaaaag gaatcgtggg aaattgggga gcagcgctga tcaatatcgg cttgattatt
    14641 tcgatcattg gttcttggtt gtcttggacg atgctcccag cagaaacaac gatgttgatg
    14701 gctcgagacg gtctgttgcc gaaaggttgg ggaaaaacga ataaaaaaaa tgccccaact
    14761 tattcgttag ttgttactgc aatcttgact aatctattct tattgacttt cttagttact
    14821 gattatgcct atcaatttgc ctattcttta tgtacagcgg caattttgat ttgttatcta
    14881 cttgtcggga tctatcaagt ccagttttct ttaaaagaag gaatcaaaaa acaagtagtg
    14941 atcggtggga ttgctgtagc ttttgaattg atgggcatca ttttagcagg attttcttat
    15001 gtccttttat gtagtattgc ctatcttcct ggtttttgct tctactggat cgcttgtcgt
    15061 gaaaccaaac atcaaattac gggaaaagaa aaagtaatga ttgggctgat ttgtgtggcc
    15121 gcactgcttt caatcgggtt gcttgctgta ggctggatca agatataagg gggaaagaaa
    15181 catgaaaatc gcaaatttcg gtgtagaaga atggctaaat aaatgggaaa agaaagcggt
    15241 atatgatatt gcacaaagct cgatcgaagc attgacatta gacgaactcg ttggcttaga
    15301 tgggactagc gtaagtgaat ttttcgaaaa acgcaaaaac gaaccattgg actatggctg
    15361 gatcgaagga tcagatgttt tcaaacaaga agtcgcttct ctttatcaaa ccgtcgatcc
    15421 ggaaaacatc ttacaaacga atggagcgac tggtgctaat cttttagctc tatacgcgtt
    15481 agtggaagca ggagaccatg ttgtttcgat gcttcctact tatcagcaat tatatgacat
    15541 ccccaaatct ttaggtgccg ctgttgactt tgttcatttg aaggaagaag aagattggca
    15601 gtttgattta gaacagctag aagccttagt caaacctgaa acaaaaatca tctgtttgaa
    15661 tagtgcaaac aatcctacag gcacattgct agatcggaaa actttagaaa aaatcgcaga
    15721 aattgctcgt acagtagatg catatgtatt gatagatgaa gtatatgcgc ctttaacgga
    15781 taaaggtgaa ttcttgtcga tcgtagatgt ctatgaaaaa ggtatagcaa ccaattccct
    15841 atccaaaacc tactccattc caggtattcg tattggctgg acagctactg gacctgagtt
    15901 ggcagaagtt tttcgaaagt atcgagacta cacgatgatt tgcggcggag tcctgtcaga
    15961 tgatcttgct gtacatgcat tgaagaataa agaaaaaata ttggagcgaa acaaaaagat
    16021 cattacagag aaccttgtga ttttaaaaca atgggtagcc aatgaaccga aagttgaact
    16081 tgtcgctccc aattacgtct ctacttcttt cattaaatta gccatcgaag aagatgacca
    16141 gacattttgt atcaatttat tagaagaaac aggagtacta ttagtaccag gaagtgcctt
    16201 tgatttaccg aagcatgccc gactaggtta ctgttgtaaa aaagaaacct tggaaaaggg
    16261 attattcctc ttatctgagt tcttgaaaaa acaggcctaa acaaaaacac tgcaaggaca
    16321 gtctgtgaca actgttcaag cagtgttttt catttacgct tattgtctat gagaaggaga
    16381 gtgccctgaa gatatggaga ctcctgaagc tttttcttct gcagtttctt gctgatggat
    16441 ctcttgtgta ttgtgtcgta caagcaagaa gttgaccaaa acaagaagag aagtcgaaag
    16501 aaagacgcca cgataaccaa atgcactaga aacactggag ccgatcatag gtcctactac
    16561 gttaccagtt gcttggaaag attggttata actgaagatc cgtccagcag cttgatgagg
    16621 agaatatttt gtgatcaatg cttggacagc agggagcaga caagcatcag agatacccat
    16681 caaaaaacgt aaggcagcta attgccaaac attcgtgacg aatgccattg ggatataaac
    16741 cagaatcgca aaacccaaac caatcgcaag tattctttca ctcccaatct tgtcacctaa
    16801 gcgaccaaat cttggagcgg ctatcaaagt ggcaatccca ggtatcgaag cgatgattcc
    16861 gctgatcaac gtaacattcc catgtccatg cagcaattgg cgaatgtaca gactgatgat
    16921 tggactaatg gaattgttgg atgcttggat gatcatcgtt gtgacgaaca taccgatgac
    16981 gacgtgtgga tatttcaagt ctttgaaaat ctgtttggca gaaaccatgt tttctttttt
    17041 cactgggaca aatttttcat ggacgaaaaa cagactcaac aagaagacga aaaataagat
    17101 gatccctgta atgaaaaagg tagggcgata gccaaacgct gaagcagaga tcccgccaag
    17161 aagcggtcca agtaatgttc ctgtaacaga accagttgct aaagttccaa gaacttgacc
    17221 acttttttct tttggcgtcc cagttgcgac aagggcagcg gcattactga tataaccaga
    17281 aaaaatccct tgaagcagac gcaatgcgac taattgatac acactagtca cgcaacccat
    17341 caaagaaatg acgattgcca ttcctaatga agcacgcaac agcatcaatt ttcttccttt
    17401 ttggtgggct aattttcccc accaaggaga gatcagcgta gtcaccaaga aagtagatga
    17461 aaaagtcaat ccgctccaaa agttcaattg tgacgtacta taattaccta acgtatctat
    17521 gtaaagtgac ataaaaggca tgactaaact aaatccgata ccagccataa atgttccaaa
    17581 ccataagaca aacaagtttt gttcccaagt ttctcttttc ctaaataatt tttcctttat
    17641 tcttgcagcc aattagactc cttctttctg aaaattttca tctacagctt tttgttataa
    17701 actacaatat gtagtttatc aatgaaagtc tcttttttct ctttcttttt cgtggtaaac
    17761 tgaaagagtg aaggatttat tttatgagag gaaacatgaa aatgaaaaaa agaaatctgt
    17821 ctcaagagaa aatcatcgac tgctttcgag aactagcaga agagatggat gttcagcaaa
    17881 taacctttca gcatttagca aaacgcttgg atatcaaggc tccctcgctg tataaccatt
    17941 tcaaaaatat tcgtgatgtc aaaacagcgc taacagcgaa acttctgcag gaacttaatg
    18001 accagctgcg tcgggctctt gtgggaaaaa gtggtcagga agcactgcag atctatgcag
    18061 aaacttatcg atcctttgct ttttcaaatc aagcagtgta tgagttactg atcagtgtgc
    18121 cccacaccaa tgaagcagtt ttattagagg gaatccatga aacgaaccag atcattttgc
    18181 agatctttga ggcttttcaa ttaacgaaag aagaaaaagt ccaccgaagc agagaattat
    18241 gtagtatgat ccacggctat ctttccttgc gttttttagg atactttaca aaagaatcga
    18301 caatcgatcc agaggacagc tatttttgga tgatcaatga ctttatcgct actttgcctt
    18361 aaacaatcag attcatttat atcattttca agatgttcat taaatgatcc ttttataaga
    18421 gaaaattctt gcaactttct tgaaaagtga ctaagataag tctagaaaag ctgaaagaag
    18481 gagcacgagt atgtatcaag taattaccat gttcggggac aatgagcctt ggtggttttt
    18541 tgaagactgg gaagaagata ttgaagcaga agaaacattc gagtctttcg aagaagcacg
    18601 acaagcgtac gaaaaacaat ggaacgaaat ccatcaaaat tatgaatata tcaatgcaaa
    18661 aagtaacttt ctcagcgcct tttggaatga cggagatgag cgctggtgtg aagagtgtga
    18721 cgatgattta cagcaataca aaggacttgc gttgttgaaa aatcatcagc ccatcacagt
    18781 agaaagcgga aaggaatttt atgaaacaac taattctagc ggaaaaacca agcgttgcga
    18841 aagacctaag caaggtgctt ggtgctaatc aaaagcacaa aaattattat gaaggaccca
    18901 aggtgatcgt tacttgggcc cttggtcatt tattaggatt gaaaatgccg gaagatctga
    18961 ataaggaatg gcagagctgg caaatggaca cgttgccaat gatccctaaa aaactaggaa
    19021 tcaaaccact tcctaaaaca ggacatcaat taaaagcaat caagcagctg gctcagcgaa
    19081 aagatgtctc agaagcagtc attgcgacag atgccggaag agaaggggaa cttgttgctc
    19141 gctggatctt agagtatgtg catttcaata aaccagtgaa gcggttatgg atctcttctc
    19201 aaacagataa agcaatcaaa actggattca agcaactaag acctgcgaaa gaatatgatg
    19261 cattgtatga atctgctctt gcccgggcaa aagcggactg gctggtagga ttgaatgtga
    19321 ccagagcctt aactgtgaag tacgcggata atttatcagc aggccgtgtg cagacaccga
    19381 cactagcatt agtgagagac caagaaaaga aaatcgagca gttccgtcca caaacgtatt
    19441 tcacgatcac gttgcaagct ggaaaagaac aagccaaaat gcttcaaaaa aatcaatttg
    19501 ctttaaaaac acaagaagaa gcacaaaaac ttgttcaatt gatcagtaca agcaaaggaa
    19561 ctgtcacaga agtccaagaa aaattaaaaa cggaatctgc gccattgcct tatgatttaa
    19621 cagagatcca aagagaagcc aatcaacgct atggctattc tgcaaagaaa acattaagtc
    19681 ttgtacaaag tttgtatgag acccataaga tcgttactta tccgcgtaca gacagcaaat
    19741 atctgacaaa tgacatgaaa agtacgatga aagaacgatt gcaagcagtc agcgactttg
    19801 ctcctgaggt caagcagtat ttgaaaaacg gagccatcgt ccaacagaca aaagtattcc
    19861 aagacagtaa agtgaccgat caccatgcac ttttgccaac tgaaaacaga gcacgttatg
    19921 aaaaattaag taatgaagag caaaaaatct atcaaatgat tgtctctcgt tttttaggac
    19981 tgtttgctca accccataaa gtcagccaaa caaaagttac ggttgaattt ggtaaagaac
    20041 gattcatttt tcggcaaaat cgtgtcgtcc aagcaggatg gaaaggcgaa actgaaactg
    20101 agacggaaac agtcaaatgg gaaaaagaaa tgagaatcaa tcccgatttc accatcaaaa
    20161 aagaactatc tgcaccgcct aaaccattgt cagaagcaag cttgcttggt caaatggaaa
    20221 aatacagtct gggaacccca gctacgcgtg cagagattat cgagaaacta atcaaatctg
    20281 aactgatgga acgtacccct caaggactgc aagtatctcc taaaggtaag caattattag
    20341 tattggtaaa tccctcttta gtaacaccag atttgacaga aagctgggaa aaagaccttg
    20401 aagctattgc tgcaggaaag aaacaagcag gaaccttctt gaatggaatc gaaaaagaaa
    20461 caaaacgctt ggtgaatgag atcaaatcaa gcaaacaaga atatcaagat ttctcgatta
    20521 cccaaaagaa atgcccagaa tgtggggcca atctgcgcga gaaaaacaca cgtgacggca
    20581 aaatctatgt ctgcaccaat tcagattgca actaccgcag aagaaaagat ccaaaagtct
    20641 ctaatcatcg atgcccgcaa tgtcaccgga aaatggaaat catcgaaggt aaaaacggtg
    20701 cttatttccg ttgtaaatac gatggaacga cagaaaaaat gcttgataaa aaagagcaga
    20761 agaagaaaat gaccaaacat gaagaacgac gcttgctgaa aaaatatgca caagcagaag
    20821 aaccagaaga aagcccatta gcagcagcac taaaagcagc aatgaagaag taataagata
    20881 tgaaagaggt tgtgatagaa gtggtcagct tcaagaaata agaaggaatt tacgaaaatt
    20941 gcttctcaaa tttttgtgaa atttcggctt atttccgaag aagctacttc tggaacacca
    21001 tttattcgga aaaaaggact gtgacaagac ttttgtcaca gtcctttttc atttaaaaaa
    21061 atgtttactt catttgacgt atattattgg tgaggcttca attcatttgg cttcactttt
    21121 tctgtttctc ttatgatata aacaggacgc tgtttcgttt ctaagaagat tttcccgata
    21181 tatttcccga tgattccaag acataacaat tggattccac caatgaacag gaagatcgag
    21241 accatggaag gccatcctga tgtaggatca ccaaacaaca atgcccgcaa aataatgaac
    21301 aaaattgcaa taccagaacc gacacaagac aaagcgccga taaatgaagc aatcgttaac
    21361 ggtgcatccg agaagttcac gataccatca atcgagtagt tgaataattt ccagaaggac
    21421 caagatgttt cgccagccac acgttcgcgg ttttcataag aaatatattc tgttttaaat
    21481 ccgacccagc taaataatcc ttttgaaaat cggttgtatt ctgttaattc taggacggca
    21541 tccaccattt gacgagtcat caagcggaaa tcacgagcgc catcgaccat ttctgtatcg
    21601 ctgattttat tgatcaactg gtagaatttt ttcgcaaaga aactgcgtat cgcaggctcg
    21661 ccttcacgag tcgaacgccg ggtgccgaca ctatcgacat cagaagtagt gatccggttg
    21721 atcatctcag gaagcagttc gggcggatct tgcagatcaa catccatcac ggtcactaaa
    21781 tctcctgtag aagcttgcaa tccagcgtac agagccgctt ctttcccaaa atttctggaa
    21841 aatgagacaa agcggacata aggataagct gaggctagct tcttgattgc tgctaacgta
    21901 ccgtcttttg atccgtcgtc aataaacaaa tattcgaact catgggcacc tttgaatttt
    21961 tcaacctcat caaaaaaaag aggaacagtt ttttcttcat taaaacatgg gacaacaatt
    22021 gatactttca tcgtttctat cctttcaatc gtatgtttat atatggttta cattcaaaat
    22081 ttaataaacc ttaaataaca ccttttaaat ttgattttat ggaaaagaac agctattctt
    22141 tggtaaacta acgtatttag tttaccatgt ttcctcggtt tatcaaactt ttaagaacaa
    22201 tttttattag ttggcaagta gttttggata gagaaaaagg aggaagttcc agtctactga
    22261 ccaggagcaa acaaaatgaa aatacacaca cctatcggct ttttatggtt agatgcagat
    22321 gaatccggat tgactgctgt atcttttcag ccaatttcag aaagcgaatc agcgaatcag
    22381 caaattttaa cgcgcacaca agaacagttt gaagaatatt ttgcgggaaa aagaaaagaa
    22441 tttgatgttc ctttatctat aaagagaggt acgccttttc agcaaaatgt ctggaaagct
    22501 ttgtcgacca ttccttatgg agaaatccga acgtataaag aagtagctgt tgctgttgat
    22561 agtccgaaag ctgtgcgagc gattgggcag gcaaatcgaa ccaatccatt gccaatcgtt
    22621 attccttgtc atcgagtgat cgggcaaaat ggaaaactga caggatatat gggaaacgca
    22681 atagatgggg ttgaaatcaa acgccaattg ttgttgttag aaggatatct gcaaaattaa
    22741 aaacagttgt gattcggaca ttgttccatg cgagaatcac aactgttttt tcatgttcat
    22801 tctaaacttt gatcagccaa ataaatagta aagccatcac tgtttggaga agcccgacag
    22861 ctaatccata agataagaag cgtgtacctt ctttcatgaa ttttgcaaag tctaaacgca
    22921 gaccaattgc cgctaaagca gtgatctcaa accagctgct gataaaatgt gccgattggt
    22981 caataactac aggtaaagaa aacaagctgt tgaccaaaca aaagatcaca aaccctaata
    23041 cataccaagg aagtggtaat tttcgttttt tctgcgtatc agttggcgtt tcaaacagag
    23101 ctggttgttt cttgtgcatg aatttttcaa acagatagac aacaacaacg agcatcataa
    23161 tacgtagaat cttaaatagc atggcgaatt cgacaacaga attgtcaagt aagcttgccc
    23221 cagcgactac ttgaccaaca gattggagtg tgccacccaa aagtgcactt ttttcaatga
    23281 gatttccacc aaacaactgt aatccaagga aagggagagt caacatcatc acagtaccca
    23341 gtagattgac tagtgtgatg atctgtcctt tttcttcctc tttcgcatgg atggaagggg
    23401 cgatcgaagc aatagcagaa gaaccacaaa cagcgtttcc tccagccatc atcaaagaag
    23461 aagtatcgct gaattgcagt tttttaccaa tcaagtaagc accgatgata gtgactgaca
    23521 tttgcagtaa cacaaaaaca attcctttta taccaatttg agcaatcgtt tgagctgtga
    23581 cagttgcacc tagtaaaaaa acagagaatt ctaatagttt gctttcagca aattttgtgc
    23641 cgattgctag aacaggctgt ttaaaaaaag tatttcctaa taaaataccc aataaaatag
    23701 caatagtcgc tccacctaac tgtggcagat aaatagcaag aagcctgctg aaggcagcga
    23761 tggcaaaaga aagcagtaaa ccgggtaaga tttcgcggac cgctgaatcc tttacagatt
    23821 ttattggatg tgacaatgat ttcatttgat cggttccttt cgtcaataaa tactaaaagc
    23881 atactcgaac atagtagcac taaaccagta ttttgacaaa agaacaagag gtcgtgacaa
    23941 aagtcttgtc acgacctctt gtttcgaata aacggtgttc aaaagccagt ttctcggtat
    24001 taagccaaat ttatgcaaaa atgtggaaag ccattttcac aaaatttttc ttaatactcg
    24061 aaactaagcg gctttttcac gacctcttgg taaacggtgt tccagaagta gctttttcgg
    24121 aaataagccg aaatttcaca aaaatttgag aagcaatttt cgtaaattcc ttcttatttc
    24181 ttgaagctgg ccacttcttt tacgacctct tggtaaacgg tgttcaaaag cttgcatctg
    24241 cggtaataag cccaaccaat tcaaaaacat gaacagctgt ttttgtttgg ccgttcttat
    24301 tacttgatgc agaacagctt tttcacaacc tattgaatcg attattaagc gattttttta
    24361 gaaacaaatt ttccatgttt gctatgttct ttaattaaga aacgtacgta atgagcaaga
    24421 acgtagaaga caactacact tgcaaacaga cattccgcaa cttttaagaa atccaatacg
    24481 ctactataga tacctaaact gttgaagtaa tgaacagtag taaatatagc tgttgcagag
    24541 ataacaagcg ggaatgtaaa ggctgcatag cttggataaa aacgaagctt gaacaaacgt
    24601 ggaagcatag acagcacaac gaaatacaat acttgagata aagcgaacaa tgctacgaca
    24661 agataaaaat taggttcagc aaagttttta agataacctg ttaggcaaag agaaccaggt
    24721 gctgcaacga tcgtaatcag cggacgtgtc ggatgagcca tatttcttac gaaaaagaca
    24781 cgtttgatga tgatcggcaa taagaacgca tagcagatca atgaaatcca aaagaaaatt
    24841 tttccaataa gcgggaagaa gttcccggca gttacagtga tgaccccaaa tccaacataa
    24901 atgataaacc agcttggata aattgcttca attgaaagat cagctttgat aacatggtga
    24961 taattgaaat aaaagacaag gatcacttgg aagataacag cgcacagcca aatgaatttg
    25021 acaattggtg caatactttc atatgaaaca aaataagtac aaataaccat gagtgacatc
    25081 gtaaaagttg gtgaaacgga ggcgatgatt ggatcatgca acgtttgttt cgtgtgttcg
    25141 aataagataa acaatttaac aaaaatgaat atcataagaa tcatagagat accgccagtt
    25201 agattgccta aagcaacatg gtgatagtct ttaaacagat ttccaaggga agctaaccca
    25261 aggatcaacc cgcagatcgg gatcggaata attttcaaaa agttcttcat atataatatt
    25321 ctccttttta tttaatagat tttagtacca agatgaacga atacattgta aaatgaatag
    25381 gaatgtatga ttacgagcaa gcagacagct gattgtcttc atctaagtta ctagttggat
    25441 cagcaactgt tttgttgtac atttctatta tagatggttt tttgtatatt taaatcaaat
    25501 agtttttata gtaattatca taaaaagtta tggaagtggt gccatgttta agttattaac
    25561 gacttttcga gcagtatatg aaacaagaaa tttttccaga gcagcagaag tactgttttt
    25621 atctcaacca gcagtctcga atcaaatcaa acagttggag cgggaattga atatcgatct
    25681 ttttcaacgt aacggaagaa aagagatgct tccaactaag caagccgact tattatatga
    25741 acggacactg gttttgttag aagaatggga agaaactcag caaaaattgc tcaatgaaca
    25801 aaatgaagaa gaagtatgtc gaatcgttgc ttcccacacc tttgctgtct atcctttgcc
    25861 tcagttgatg aaacatctga tcaaaaggtt tcctaaagtg cattttgaga tcgaaatcgc
    25921 gaattctcat gaatcattag aacaagtagc gaaacatgaa tccgattttg gttttatcga
    25981 aaagccatta gagacttccg gcgtacaaag atactctttg atggaagacc agctagtcat
    26041 cgctggggac ccaaaaagca aattgtggct tgtaagagaa gcaaactctg gtgtttttca
    26101 ttacacgcag cgttattttg aagagatgaa tatccaagat aagaagatga tcgtgaaaag
    26161 taacgatgta attgttgcgt tgctgaagga aggaatcggt cgctcgattt tgtctaagcg
    26221 ctctgttcca gaaaatgtgc caatgactcc gttgaatttc catcgttatt tttatttcat
    26281 ccaacgaacc aatctggttt ctgatcagct gctagagatt gccgaagaga tccttcgata
    26341 caatgaaagc acagaaactt ctcacagcga ggagaatctc agttggtaga taattgcatg
    26401 tatcaaaaaa agttctatga tacactaaag ataagcagta ggcttttgta ctgcatttgc
    26461 tcaagcaact gcacaaacgg aaagttaatt tttcccaaat gtctatggaa agactttcca
    26521 ttatctaact ggaccgctat aataatcagc agtatggttt ttaagaaaag ggatgaaaca
    26581 tggaaaaaaa attaaaagct tcgaacgata atcgtattga ttatggtgtg attttaccag
    26641 tctttctgtt atgtttgatt ggtctgctct cattatatgt agcacttagc catgatccga
    26701 acaatccagc agtcttgaaa ggcgtaggga tgcaagttgt ctggtattta gttggagcgg
    26761 cagcaatcgt tgtcatcatg catttgaatt ccaaatggat ctggaaactg actccttact
    26821 tttatggttt ggggttagtg gtaatgggac tcttgctcaa attctatgat cagaatttag
    26881 ctgcttcaac agggtctaaa aactggtttc gattcggtgc gtttactttc cagccagcag
    26941 agttgatgaa gattgcgtac atcttgatga tggcactgat cgtaactaaa cataatacgc
    27001 aagtaaaaga acggacgatg aaatcggact tttggctgat tgggaagctc ttgatcgtga
    27061 caataccggt tttagcattg atcatggccc aagatgactt tggaacgatg cttgtctttc
    27121 ttgcgatctt tggcgggatt ttcttgatgt ctggaatctc ttggcgcatc atcgcacctg
    27181 tagtaatctt ggcagtagtc gttggagcag gaacgatctt cttggttacg actgaaggcg
    27241 gaagagactt gctttacaaa gttggcttca aatcttatca gtttgcacgt attgattcat
    27301 ggctggaccc tttccatgat acgtcaggaa tgagttatca gccggcccaa ggacttttgg
    27361 caattggtac cggtggcttg tttggtaaag gattcaacgt aagcaatatt tatgtgcctg
    27421 ttcgtgagtc cgatatgatt tttaccgttg tcggtgaaaa cttcggcttt atcggtggtg
    27481 catttgtcat tttcttgtat tttattttaa tctatcgtat gattcgggtg tgtttcgata
    27541 cgaataatga attttacgcc tatatcgcaa gcggtttgat catgatgctg ctgttccatg
    27601 tctttgagaa tattggagca aatatcggat tacttccttt aacagggatc ccattgcctt
    27661 tcattagtca gggaggatct tcgattttag ggaacatgat cggtatcggg ttgatattat
    27721 cgatgagata ccaaaatgaa gcacctgcaa gatcttcaag gaggtaagaa aattgtacac
    27781 cttttactgg tacccgaaat gttcaacatg caaaaaagcc aaagcgtggt tagaccagca
    27841 tggcgttagt tatcaaactg ttgatatgat caaagaagta ccgaaggcct caacgattga
    27901 gacttggcta gaaacgagtc aagtaccaat ccgtcgcctg ttcaacacaa gcgggatgaa
    27961 atatcgggaa cttggactga aagatcaagt aggcgagttt acggcttcaa aagcgagcca
    28021 agtcttatcg acagatggta tgctgatcaa gcggccactg atcttacgag aggaccagct
    28081 tgttgcaatt ggattcaatg aaaaaattta tgaaggagaa ctgatataaa atggcaggca
    28141 agcatttgaa gaaaaaggac aacctttgga tcttatttaa tggaaaagaa tactgtgttg
    28201 gtttgacaaa tgaagcgcaa gaagaacttg gagacatcac gtttgccaat ctgccaaaag
    28261 caggacaatc gctaaaaaaa gatgaacctc tgatcgaagt tgaagcggaa aaagcggtca
    28321 atgaatttgc cagcccgcta acgggtacag tttcttctgt taatgataaa atcggtgaag
    28381 atatcaatat cttgaatgat tcagatgaaa tgaatgcgtg gatcttaagt ttcaaagatg
    28441 ttgatccaaa agaatttgac gaattataaa atcagaaaat cacttgaaaa aagttgacac
    28501 tgattcttcc agttgctata atcataagca atcctatatg aaacgagaaa gctttgaaaa
    28561 gaagagtaca tgtcacggac gtttgaagag agccctgttt gctgaaaatg ggtaacgaaa
    28621 atgagatgga agatggtctt agagcagagt aagcgagcgt aagcaaactt actacgggag
    28681 tgcccgttac agcgcgacag tatacggaaa gaagctaagt ccaagtactg gaagaggctg
    28741 ttattgcgaa gtaacggtaa atcaaggtgg taacacggaa gttcaagctt tcgtcctttt
    28801 gcttaaggca agagggcgaa ggcttttttg tttgaaaaat cataagagaa agatgtgaat
    28861 ggcatgtcat taatccaact aacgaatgtc aaaaagacat tcaatgggaa aaacggaaac
    28921 atccaagccg tcaatgacgt ttcactaaac gttgaaaaag gggatattta tggaatcgtc
    28981 ggctattctg gcgcaggaaa aagtacatta gtccgtctcc tgaatggact tgagcttccc
    29041 acgagcggcg aagtgatcgt aaacgatcaa gatattacaa aattaaaaaa caaagaatta
    29101 cgtacattcc gaaagaaaat cggtatgatc ttccagcatt tcaacctgtt atggtcaaga
    29161 actgtacttg aaaatatcca gctgccgctg gaattagctg gcgtaccaaa gagcaaacgt
    29221 aaagaacggg cagaagaact gttgcgttta gtcgggttag aaggacgcgg acaagcatat
    29281 ccttcacaac tttccggcgg gcagaaacaa cgcgtcggta tcgcacgagc attggcaaat
    29341 gatcctgaga tcctgctttg tgatgaggct actagcgcat tggacccgca aacaacagaa
    29401 gaagtattag acttattgtt agcgatcaat aagaaattga atttgaccat cgtcttgatc
    29461 acacatgaaa tgaatgtgat ccgcaaaatc tgcaacaaag tcgctgtgat ggagttgggg
    29521 aaagtcgtag aagaaggaga cgtattgact gtcttcagac aaccgaaaaa agaagtaacc
    29581 aaacgctttg tacaacaaga catcgaacca gaagctgatt cgacagaact attagctgaa
    29641 ctcatcaaag aaaatccaag cggccgtttg gcaactttga cctttagcga aagaaatgcc
    29701 aacgagccag tcatttccca agcgattcga cgctataaca tcgatgtcaa cgttgtgtat
    29761 ggaaagatca aacaagtgaa agaaggttcc tttggttcat tgactgtctt gatgactggt
    29821 gaaaccaaag aattagatca agcagaagtg ttcatcaaag aacaaggagt aggaattgag
    29881 gtgatccatc gtggataaaa gcttttcaga aacatatcta gattttaaac aaatcaaccc
    29941 ggaaacgatg aatcaggcta tccttgatac actatatatg acattaatct caatggtctt
    30001 agtgacgatc atcggattag ttttgggatt gatcctttac tctattggac gcaaaaacaa
    30061 accgtatgct cgaatcattt atggaatcgt atcgatcatc agtaatattt tccggtcaac
    30121 gccatttatg atcctgatgg ttttgatcat tccatttact aaagcaatcg taggcactat
    30181 gctaggtgcg caagcagcca ttccagctct tgttttatcc gcagcaccat tttatgcccg
    30241 tctagtagag attgcttttc gtgaagtcag ccctggtgta ctggaagcag cagatgcaat
    30301 gggagcaagt tactgggaaa tcatctggaa ggtcttgata cctgaaagta ttcccgcatt
    30361 gatttctgga ttaacagtta caacgatctc gatgatcgga tttactgcga tggccggcgc
    30421 gatcggcgca ggtggacttg gaggtcttgc ttggcaggaa ggctaccagc gtggtaatct
    30481 gacagtgaca ttcgttgcga ctttaattat tttactaatc gtatttatcg ttcaaggaat
    30541 cggtgatttc ttaactaaga aaacagacaa aagataatag gatatagggg gatgtaggat
    30601 atgaaaaaga aaatttttgg attagcagca gcgcttttgc tgactgtagg attagcagca
    30661 tgcggtaaca acagcgacag caaagattca gcaaataaag cagacgacac gacattgaaa
    30721 gtcggcgctt caccgacacc gcacgcagag attttggaac atgtgaaacc attattgaaa
    30781 gatgaaggaa tcgatcttga aatcgtcaaa ttcgatgact atgtattacc gaaccaatct
    30841 ttggaagaag gcgacattga tgccaattac ttccagcata ttccttattt gaacaaagaa
    30901 atcaaagaaa aaggatatga ctttgtcaat gccggtgctg tccacatcga accaatgggc
    30961 ttgtactcta aaaaagtcaa agatgtttcc gaattaaaag atggtgcaac aatcattact
    31021 tcaaattctg aatcagactg gggacgcatc atcacaattc tacaagatgc tggcttagtc
    31081 aaagtcaaag atggagtaga tctggaaaca gcaacattcg ataatattga agaaaaccct
    31141 aagaacttga agttcaacca tacgatcgac ccatcacttt tagcttctac gtaccaaaat
    31201 gatgaaggtg acctagttgc aatcaacgca aacttcgctt acggcgcagg gttgaatcca
    31261 ttagaagatg ccgtattgct tgaaaaggac aactctcctt acgtgaatat tattgcgact
    31321 cgtaaaggtg atgaagacag tgacaaaatc aaaaaactga ttgaagtgct tcaccgcaaa
    31381 gaagtccaag aatggatcac agacaaatgg ggcggctctg ttaaaccagt aaaggctgat
    31441 gcaaaataag gtatggaaca aaaaagatga gaaataagtc tgtaatggct tatttctcat
    31501 cttttttata tctattctaa tttagaaatc aaaattgttt aataataaat aaaagatatt
    31561 tgattttagt aaggaaggtc attgcgcttc attctcaatt agtctaaaat gagtgagaac
    31621 gaaagagaat ttgggggtat aatgcatgtc tgtcttagaa ataaaaaatc tacatgtgtc
    31681 gatcgaggaa aaagaaatcc ttaaaggcgt aaacctaaca atgaaaaccg gagaaatcca
    31741 tgccatcatg ggacctaacg gcacaggaaa atctacctta tctgccgcta tcatgggcaa
    31801 tccaaactat gaagtaacag aaggcgaaat tttgtttaac gggaaaaatg ttttagactt
    31861 ggaagtagat gaacgtgcgc gacttggctt atttttagct atgcaatatc caagtgagat
    31921 accaggtatc acgaatgcgg aattcatgcg tgcagcgatc aatgcgaaac gtgatgaaaa
    31981 cgacaaaatt tctgttatgg catttttgaa aaagttagat gaaaaaatgg ctttactaaa
    32041 tatgccagaa gaaatggctg aacgttatct gaacgaaggt ttttctggcg gagaaaagaa
    32101 acggaatgag atcctgcaat tgttgatgtt agaaccaaca tttgcaattt tagacgaaat
    32161 cgattcaggt ctggatatcg atgctttgaa agtcgttgct aaaggagtaa atgaaatgcg
    32221 cggagacaat ttcggtgcat tgatcatcac ccactatcaa cgattattga actatatcac
    32281 acctgatgtc gttcacatca tgatggaagg ccgagtagtc atgacaggga atgctgacct
    32341 agctaaacgt ctggaagcag aaggctacgc tggtatcagt aaagaattag gaatcgacta
    32401 taaagaagaa gaagcgtaag ggggagcaag aatgaaagaa aaaaactggc tcgattatct
    32461 tgacgcggta aatgattttt ctttaagtaa aggagaacct gattggatga gaaccttccg
    32521 tcaagacgca ctagcgaaag cagatgaact gccattgccg catatcgatc gggtgaaatt
    32581 ccatcgctgg tcgttatttg atgtgaaaga aacacaaacc atcagtgaaa caggcacgat
    32641 tccggcattt gatgcaatga aagacaatcc tgtgcttgtc caacaaggtt catggacgat
    32701 ttttgaacaa ctgcctgtgg aattagcaga aaaaggagtc atttttaccg acttgttcac
    32761 tgcaatgatc gaatatccag aactagtcca agaatattat atgaaaaaag cagtaaacat
    32821 gaacgaagac caattgactg cactccatgt agcttttatg aacagcggta ttttcctgta
    32881 tgtgcctaaa aatgtcgtga tcgatgaacc actcgagtcc ttattcattc aagatggcgc
    32941 atccgatgag cacttcttca agcatgtgtt gatcgtggca gatgaacata gtgaattttc
    33001 ttatctggaa cgtttccaga caaccaaaga acaagtagca aaatcatcag gtaatatcat
    33061 cgtggaagtc atcgctaaag ctggttcaaa aatcaaatat tcaaccgtag atcaattagg
    33121 aaaaaatatt acttcttata tgaatcgccg tgggcacatt ttacgagatg cttctgtcga
    33181 ctgggcaatt ggtgtcatga atgacggtca tgtgatcgct gactttgact cagatttagc
    33241 aggagaaggt gcacacgcag aagtcaaaat cgtggcaatc agctcgggca gacaaatcca
    33301 aggaatcgat acgcgagtaa ccaataaagc ccctcatacg atcgggcata ttttgcaaca
    33361 cggagtgatc cgagaaaaag gaacattgac ctttaatggt atcggccaca tcttgaaagg
    33421 ggcaaaaggt gcagatgccc aacaagaaag tcgtgtcttg atgctttctg ataaagcacg
    33481 tggtgatgcg aatcctattc ttttgatcga tgaaaacgaa gtaactgctg gacatgctgc
    33541 cagtgtagga cgagttgatc cagaagaaat gtactatctg atgagtcgag gattgcataa
    33601 agaagaagca gagcgcttag tgattcgagg attcctcggt tctgtcttaa cagcaatccc
    33661 tgtagaacaa gttcggaaag aattagtcga agtaatcgaa gggaagttga atggatgatc
    33721 gatgctaaaa agctacgcaa tgattttcct atcttatttc aagacgtcaa tgatgaacct
    33781 ttagtttatc tggataatgc agcgacgacc caaaagccaa aacaagtact ccaggcatta
    33841 gcgcactatt acgaacacga taacgccaat gttcatcgcg gtgtccatac gttagcagaa
    33901 cgcgcgaccc atgattatga acaagcaaga gaaaaagtac gggcgttcat ccatgcaaaa
    33961 gaaacagcag aagtgctgtt tactcgaggt acgacgacaa gcttgaattg ggtagccaga
    34021 agcttcggcg accgctatat caaagcagga gacgagatag tgctctctta catggaacat
    34081 cattctaatg ttatcccgtg gcagcagttg gcaaaacgaa caggtgctgt cttgaaatat
    34141 atcgaactaa cagaagaagg cttcctggat atggaggatg cagcgaaaaa gattacggac
    34201 aaaaccaaaa tcgtctccat tgctcatgta tccaatgtct taggtgtcat caatcctgtt
    34261 caagaattag ctgaacttgt ccatgaaaac ggcggggtca tcgtagtaga tggtgctcaa
    34321 tctgccccgc acagggccat tgatgtccaa gcactagact gtgatttctt tgctttcagc
    34381 ggacacaaaa tgtgcggacc aacaggtatt ggtgctttat atggtaaacg aaaatggtta
    34441 gaagaaatgg aacctgttga atttggtggc gaaatgatcg attttgtcga attatacgac
    34501 agtacatgga aagaactacc ttggaaattc gaagcaggga caccaaatat cgccggcgct
    34561 atcgcattag gccatgcaat cgattatttg caagaactcg gcatggacaa tatccatcga
    34621 tatgaagaag aactagccgc ttatgtgttg ccaaaattac aagcaattga tggattgact
    34681 gtttatggtc cacaagaccc gaattttcgg acaggagtcg ttgcattcaa tttggatggg
    34741 ttacatcccc atgatgtcgc gacagcttta gacatggaag gggtagccgt cagagcaggt
    34801 catcattgtg cgcaaccgct attgaagtac cttgaagtat cagcgactgc tcgcgcgagc
    34861 ttttatttct acaacacaac gcaagacgcc gaccgtttag ttgaagcaat catggcaaca
    34921 aaggagtttt tccagcatgg gactatctaa attagacaat ttataccgtc aagtgatctt
    34981 ggatcattct tcccatccgc atcatcgtgg aagcttgact gactcgacaa gtaagatcga
    35041 attgaacaac cccacatgtg gagatgtgat cgaattgcaa gtcgatgtaa aagacggaat
    35101 catcaaaaat atcgcctttg acggcagtgg ctgctccatc agtacggcaa gtgcctcgat
    35161 gatgacagac gccgtcatcg gaaaatcaat agaagaagca gaacatttaa ctgtagactt
    35221 tctacagctt gtccaaggaa aagaagtcaa agatcccgac caattaggcg atgctgctat
    35281 gcttggtggt gtagctaaat ttccagctcg gatcaaatgt gcgacacttg cctggaaagc
    35341 actaggaaaa gcaatggaaa acgatggtac cgcagctttc catcattacc acaaggaaga
    35401 ggagtgagaa catgggcgta ccagaattag aagaatataa attcgggttt cacgatgatg
    35461 tcgaaccggt tttcagtaca ggagaaggct tgacagaaga agtgatccgt gagatgtcaa
    35521 gaatcaaagg cgaaccagaa tggatgcttg aattccgtct gaaatctcta gaaacattta
    35581 acaaaatgcc aatgcaaaca tggggccccg acctttcaga catcgatttc gatgccatca
    35641 aatattacca aaaaccaagt gacaaacccg ctcgtgactg ggaagacgta ccagaaaaaa
    35701 tcaaagatac atttgaaaag attggtatcc cagaagcaga acgagcttat ctagccggtg
    35761 cttccgcaca atatgaatca gaagtcgtgt accataatat gaaagatgaa ttcgaaaagt
    35821 taggaatcgt ctttactgac actgactctg ctttgaaaga ataccctgaa ttattcaaag
    35881 agtacttttc aaaacttgta ccgccaactg acaacaaatt agcagcgctg aattcagccg
    35941 tatggtcagg tggcaccttt atttacgtgc caaaaggcgt caaagtcgat gttccattac
    36001 aaacttactt ccggatcaat gcggaaaaca cgggacaatt cgaacgtacg ctgatcatcg
    36061 ttgacgaagg agcaagcatc cactatgtcg aaggttgtac ggcacctact tattcaagta
    36121 atagtctgca tgccgccatc gtagaaatct ttacaagaaa agatgcgtat tgccgttaca
    36181 caacgatcca aaactggtca gacaatgtgt acaacttagt aaccaaacga gcaaaagcat
    36241 acgaaggcgc aaccgttgaa tggattgacg gaaacctagg tgcaaaaaca acgatgaaat
    36301 acccaagtgt ttacttagat ggaaaaggcg cacgaggcac catgctctcc atcgcctttg
    36361 caggagcaaa ccaaatccaa gatacgggtg caaaaatgat ccacaatgca ccaaatacat
    36421 ctagctctat cgtctctaaa tcaatctcaa aagacggcgg agaagtaaac tatcgaggac
    36481 aagtaacctt cgccaaaaac agtgcgggtt cgatctctca tatcgaatgt gacacaatca
    36541 tcatggacga atggtcgaaa tccgatacga tcccatttaa tgagatccac aacagccaag
    36601 tctctttaga acacgaagcc aaagtctcaa aaatctcaga agaacaactc tactatctga
    36661 tgagccgagg cctgaccgaa tctgaagcaa ctgaaatgat cgtcatgggc tttgttgaac
    36721 cattcaccaa agaacttcca atggaatatg cagtcgaact caaccgattg atcagttatg
    36781 agatggaagg cagtgttggg taaacctgtt ataggagcta gaacccttga tatataaggg
    36841 ttctagcttt tttgttttgc ctgtatacta gaaatgacca gattttgacc agctctttta
    36901 ctgatgagcc atcatatcag caaagtcttg acctgttttc ttaggtgcat tatttgtaat
    36961 atgtgcatag atgtctaatg tcactttact attttcatgc cctaatcgtt gttgaactac
    37021 cttgacagat tctcctgctt ctaataataa actagcatgt gtatgtctaa acccatgagg
    37081 tgtaatacga ggcaagttat attttttcaa aatatatctt aaccaatcat taacagtgtt
    37141 tggaatgtat agagtgtttt taactgttgt aaaaacatgt tgctctttag agctagtatt
    37201 gtatccaagt tttaaatact cttctttttg ctgtaatttc cagttgttga ggatagaaag
    37261 agtctcagta tctaaagaga taactcgtct agaagctctt gttttcggag attgaattat
    37321 aactttacca aattcatcta cagcaagagt tttattgaca tgtagttctt tattaaacgt
    37381 gtctatgtct ttccactgta aagcgagtac ttcactcttt ctcatacctg tgtatgccaa
    37441 taatctgaag aaggcgtatt gtttcatgtt accaaaatct ttaaaagcat ccagtaaatt
    37501 attaagctcc tcttttgagt aaaatttacg atttttctca tactcttttt ttcgtggaag
    37561 aagtgttttt tccataggat tattgtcaat atattgcatt gcaaccccgt agcgtaaaat
    37621 ttgtgcagtc tgttttctca tataatcgta actttcatat ttactgtgcc attcatctac
    37681 cactttttga caatatggga cagagatatt cgatagttta agcttaccaa atgctggaag
    37741 tatttgatta tttgcgtatc ttactgagat tgcgattgtt gaagctttaa cactggtacg
    37801 ctgatgagtt atccattcat tatacaggtc ttcaaatgtc atatcaggtg ctttcttttt
    37861 aacaccgtat aatatttgat gtctgtactc gtcataatct ttttgagctt cttgtttgct
    37921 actaaaacct cttctcgtag tatttatttt ttcaccagtt cgtggatcgg tggcaatgtg
    37981 tcctttatac atccacgcca cttgaccgtt tttctttttg tactttgata tttttgccat
    38041 taaatcatct cctcttagtt tacaaggagt acttaccact agatggtatc acctcccttc
    38101 atttttttct tagtgtattt tttcccaatt gatgaaatcg tttgttctag cttgtttata
    38161 ttatcagtaa tttctctcac agcttcttcg ggataagaca tgtctttcaa ttgaataggt
    38221 agccattcat ctaccattct ttctagtagt tcttctatac tgctagtgag gaaaagaatg
    38281 ttattgtcaa attcttctac aatagcattg atgaataatt cttctatttt taagatattg
    38341 aaaagactaa ttttttcatt tttaacttta ttacaagtct tgttagcaat aaattcttgc
    38401 atctctggtt ctaatttgga atatctatcc agccatgtat ctaaattaga gtgtactggt
    38461 gggaactgtt gacgaagatg ctggaacagg tttttatctg gaaatgttat accatctagt
    38521 acaatgctat ctctataaag aataattccc aaaatatatt cttctacatt gccacaaact
    38581 aactcctcta tactcatatt tcccaaatca gcaattcggg ataatcgctc tggtattggt
    38641 aaataggttc ccttctccca ttcgtagata gtttttttgt caattaattg accgttgtta
    38701 atcataagac caaatgctgg ttgtgttaat tttttactct ttcttatagc ttttattttt
    38761 gttccgagta tcttttttcg ttctaaataa tttattggtg gacgttttat catattgacc
    38821 acacctccta aaattagtat acctcaaaaa aggggtgttg taaataaatt ttacaaagct
    38881 gttgacaccc cttttttatc gaggtattat gtgtatgtcg atgaactggt aatcattttt
    38941 tgtttgatta atcggttaat aacaaaatac ttttattttg agcaaaaaat acgaagataa
    39001 ttcttagaaa atttgttcaa gcaatcacga aaggaggggg aaatatgtct ctacaaatca
    39061 ttgatagcat tgtttctata caagttgaac aacaagtgaa agagataatt acagtgctaa
    39121 agcctatgct agaagacatt atttctggag tcactctaga gtatatggac tatcagcagg
    39181 caagtgaata tctaggtgta tcagtaggaa cgattagaaa atatgtttct caatacgggt
    39241 tacctgttat aaaaattgat acggtcatta gatttaaaaa atctgatatt gatagtttca
    39301 tggaacggta taaaggttga gtaaacaaat aagactaaaa catatagtaa taaagagttt
    39361 gtttttatta tctgtatgtt ttagtcttta acagaatttt ataaggagga aacacaaatg
    39421 gaaacatcaa tgattaatat tccaatttat gtagatcaag aaaaattatt agagaagcca
    39481 gttacaaaaa aagaaaaaac tgatgtaaga gataggtgtt tagataacta tagagaagtt
    39541 acaagagatg agtttgtaga gatactaaat tcatcacaat catttattcc aagcaagaca
    39601 aagaataaag gcaatgacaa ggagagtttt gtggaaacca gagtaattat tctggatgtc
    39661 gataacactg ttaaagatga gaaggggaag gtagtagatt tgagtaaaga tgatagtaga
    39721 tacttaagcg tagaaaaggt tttatctatc aatttagttc ataattctgc gtttgcgata
    39781 caaaaaagta ttcggtactc tgaaaatcta gaaaaataca agattgtctt tctattaaaa
    39841 gaagcaatta ctgactatgg taaaatggtt gctgtttacg aatacttgaa aaagaacatc
    39901 cccgggtgtg atgacaatgt aaatgcttcg aatagaatgt tttttggagg atataagtca
    39961 gatgcagtga taataattaa tgaagacaac atgttagata ttactgagct tccgattgat
    40021 tttaccatga catgttctaa aaattgtcaa agtgattcag ggagagagta tgaactagtc
    40081 aatgaaaccg attttgttaa gttgataaaa aatgacgaca aagaagaaat gaaacagtgg
    40141 tttaaagact gcctgtttga ttcctccgac atgtctttta atgagattta tgaaagattg
    40201 ttaaccattg atatgaataa attacttaag tcaagtaaaa acttaagatg tctgtttcac
    40261 aacgatcata atccctctgc tagtattttt accagtaaaa ctgggcattc cattttttat
    40321 tgtcattcca gtaattgtga tatcagtgaa aattttattg gagttgtgat gctaatttta
    40381 aagaaagaca gtcgggtaga aacatttaat tggctattag agaacctaga cttgtatcct
    40441 acacattttc gaaaattgaa agaggaatca aaagtacttt ttgacactct tgaatcaatg
    40501 aaagacaaac ttttcaggac aataaggaat tatctagagg aaatgcgacg tgtctatgat
    40561 gtcttgcttt ctgatgttaa tttttttgat gatagtaagg aaagtgtgac ttgtattttg
    40621 tcgggggaac aattagctaa aaaaatgagt tcttactatg gtaaaactta tgacatagat
    40681 aaatgtaata agttactatc acttatgact tttataggat tgataaaaaa attagatgat
    40741 gaagatgttc ctttgaagat gctcgaatac ctaaataggt taaaggaaga gaaagcgtta
    40801 ggaaacttta atcataagag aagcaatgtc tatcgattag acgtttttaa tgcaacttct
    40861 gtgattcaaa aattgaatga agatatcctt ccacttctgg aaaaaattca ttttacatat
    40921 caatattttt cttatgaatg ggttaagata tgttttaacg aaaaagaggc taaaagagta
    40981 tttcctcaaa attcccgatc agaactcagc aaggaaaaac aattgatttt agatgaagca
    41041 catgaagttt tacagggctt atcgtggcaa gggacatatc taatgacaga gaaagaactt
    41101 attaacactg tttgtgaacg cctacgtaat gttggggata acagcgtgaa aaatgcttta
    41161 ataaaaaaca gaggctactt tgttaaacaa ggattcactc ttgaacgagc ttctaaggat
    41221 attaagaaac tatacaatgt gaaagcaagt agtagttttt taatatattt agcgaaaggg
    41281 gcagggatag atgaaacaat aaaagaattg atattatcag gagctgggat agttcctctg
    41341 tatcaattta caagtgtaac aagagatgat ggacggagag taaggaagag aaaagaccca
    41401 attgtattaa actagacagg ttatccatag ctcttaatct tatttcatct caatacaccc
    41461 accgttaaag ttcggtgggt tatttatttt tcaatctttc aatagctgat tgcgttcatt
    41521 ttcttgcctt tttaatagct tcatatagtc aattgttcga actgcatctt cagtgctaag
    41581 agaacgatag agagccaaaa actcttcctc ataatctacg acaacattgt ctagaaaatg
    41641 gcttacaggg gttcctaggg ctctagaaag agctgttaag ctatcgaggt taggctctgt
    41701 tacagaattt tcccatcttg ctactgcctg ttgtgtagag aagatttttt cagctaattc
    41761 tttttgtgtc cacccgagag cttttcgctt ttctctaatg acctttgcat attgtttctg
    41821 tttcattaat acacccccat ctcagtatag tacaacaagt tgttgtattt gtaatggtat
    41881 ttgaagtttt ttatatttta tgagtttaaa tacatcatat tgttgtatat aataaaacag
    41941 gaggggagaa tcatgaaaaa agtaagtaat ctcagccgat acagaaaaga aaaaggactt
    42001 tctcaaacgg agttagcaaa aaaaatgaat gttacacagc aatgtgtaag ttcgtggcaa
    42061 acagggagaa cgattcctaa accctatcaa atgaagatgc tttctgagat attaagtgta
    42121 ccaatgaatg agctgttttc tgatgtattt aataaagtaa acagttaact aataagcaat
    42181 tgaatgattt taggaggaga agacatgtat tgtagaaaat gtggcaaaga aataacagat
    42241 gaaagtaagt attgccagtt ttgtggagca ctacaagaaa cagatgagac aaccggaaca
    42301 gacacagtaa agaaaagtac tgagcagaca attaatgaaa tgaaggaaca aatcgtacat
    42361 ggacaagaga cagggaagct gtatttgatt attggttgga tttctatggt agtatcgtta
    42421 gcatttattc ctgttgtatt tggtgctgtt gctgttatta tgggctactt atatcgagaa
    42481 aaagatgaga aaatgggtac gattttgatg atagcagggg tagctggagc aatctttggt
    42541 gtacttttag ggatgtcaat gtactgataa gagggataag agcaaattat tttggagata
    42601 ggagataaaa agttgaataa agtaaatatg aacaagaagt ttgtcattat aggtattgtt
    42661 gtcttggcta ttataggtat tattttttca aaaatgacag gtacatctgg attagagaag
    42721 tcatcaaaac cattggtaac acagatttta caagaacagt acaacttaaa tcgatcatgt
    42781 gatgatgtga cgattactca tgaaaatgga gataacacat accgggctaa agctatatta
    42841 gacaatggaa gtgctatcaa cataaatatt gagtactatc caaagaaaga ccgtatatat
    42901 gtggagatac catatgctga ggtgttaatg ttaaattgat ttaaatgtat tatgcatacc
    42961 gtccaaacag gaactcccaa aggtgcaaat tcactaggga gtttttatag tttcctataa
    43021 attaaatact aatacaggtg acaaaaaaat attacaatga ttgtcgggaa tttttatgtt
    43081 attcactgtt ataacaatat aaaagaaatg aaaaagaaaa aattattatg gatatgtttg
    43141 gtatttttat tgataattgg tggaattgaa atacttacta catgtagatt agaaataaat
    43201 cagtttaaac atttgctagt taatttttaa gaatactagc ccaaatcatt ctatcgatac
    43261 ctttatatct cggaatgatt gaaattggct attgcttact gatttttacc aaaaaaacaa
    43321 gtatcactat tgttgcctat attgttggaa tgctgtttat tccatccttt actcaccaaa
    43381 ttcatcaatt tttcccaaga gcagaattgt tgaagttgtg tgatccgtta tatgcatttt
    43441 tgatgctttc acgattttgg gaatttcccg ctggttatgt aggaatggtt ttactggtat
    43501 agttaatatt agat
//
LOCUS       DAJSMK010000015        40694 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.015, whole genome shotgun sequence.
ACCESSION   DAJSMK010000015 DAJSMK010000000
VERSION     DAJSMK010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.015"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            67..1208
                     /locus_tag="ON488_000819"
                     /pseudo
     CDS             67..1208
                     /locus_tag="ON488_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(1334..2413)
                     /locus_tag="ON488_000820"
     CDS             complement(1334..2413)
                     /locus_tag="ON488_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR3231033.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLFFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(2516..2956)
                     /locus_tag="ON488_000821"
     CDS             complement(2516..2956)
                     /locus_tag="ON488_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3231034.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(3013..3423)
                     /locus_tag="ON488_000822"
     CDS             complement(3013..3423)
                     /locus_tag="ON488_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCR3231035.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(3603..4037)
                     /locus_tag="ON488_000823"
     CDS             complement(3603..4037)
                     /locus_tag="ON488_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3231036.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(4137..4985)
                     /locus_tag="ON488_000824"
     CDS             complement(4137..4985)
                     /locus_tag="ON488_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCR3231037.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            5374..7140
                     /locus_tag="ON488_000825"
     CDS             5374..7140
                     /locus_tag="ON488_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HCR3231038.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            7242..8501
                     /locus_tag="ON488_000826"
     CDS             7242..8501
                     /locus_tag="ON488_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCR3231039.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            8648..9949
                     /locus_tag="ON488_000827"
     CDS             8648..9949
                     /locus_tag="ON488_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3231040.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            9952..10803
                     /locus_tag="ON488_000828"
     CDS             9952..10803
                     /locus_tag="ON488_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3231041.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            10816..11631
                     /locus_tag="ON488_000829"
     CDS             10816..11631
                     /locus_tag="ON488_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HCR3231042.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            11782..12948
                     /locus_tag="ON488_000830"
     CDS             11782..12948
                     /locus_tag="ON488_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3231043.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            13178..13825
                     /locus_tag="ON488_000831"
     CDS             13178..13825
                     /locus_tag="ON488_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCR3231044.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            13909..14853
                     /locus_tag="ON488_000832"
     CDS             13909..14853
                     /locus_tag="ON488_000832"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HCR3231045.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            14988..16439
                     /locus_tag="ON488_000833"
     CDS             14988..16439
                     /locus_tag="ON488_000833"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HCR3231046.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            16460..17296
                     /locus_tag="ON488_000834"
     CDS             16460..17296
                     /locus_tag="ON488_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HCR3231047.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            17296..17955
                     /locus_tag="ON488_000835"
     CDS             17296..17955
                     /locus_tag="ON488_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCR3231048.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            18081..18770
                     /locus_tag="ON488_000836"
     CDS             18081..18770
                     /locus_tag="ON488_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231049.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            18776..19732
                     /locus_tag="ON488_000837"
     CDS             18776..19732
                     /locus_tag="ON488_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HCR3231050.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            19776..20288
                     /locus_tag="ON488_000838"
     CDS             19776..20288
                     /locus_tag="ON488_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3231051.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(20544..21092)
                     /locus_tag="ON488_000839"
     CDS             complement(20544..21092)
                     /locus_tag="ON488_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3231052.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(21181..22362)
                     /locus_tag="ON488_000840"
     CDS             complement(21181..22362)
                     /locus_tag="ON488_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HCR3231053.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(22598..24106)
                     /locus_tag="ON488_000841"
     CDS             complement(22598..24106)
                     /locus_tag="ON488_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HCR3231054.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            24265..24456
                     /locus_tag="ON488_000842"
     CDS             24265..24456
                     /locus_tag="ON488_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231055.1"
                     /translation="MKKRQKKENAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            24659..25576
                     /locus_tag="ON488_000843"
     CDS             24659..25576
                     /locus_tag="ON488_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HCR3231056.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            25569..26642
                     /locus_tag="ON488_000844"
     CDS             25569..26642
                     /locus_tag="ON488_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231057.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            26790..27308
                     /locus_tag="ON488_000845"
     CDS             26790..27308
                     /locus_tag="ON488_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231058.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            27289..27681
                     /locus_tag="ON488_000846"
     CDS             27289..27681
                     /locus_tag="ON488_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HCR3231059.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRHFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            27757..28692
                     /locus_tag="ON488_000847"
     CDS             27757..28692
                     /locus_tag="ON488_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HCR3231060.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            28825..29604
                     /locus_tag="ON488_000848"
     CDS             28825..29604
                     /locus_tag="ON488_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCR3231061.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            29597..29914
                     /locus_tag="ON488_000849"
     CDS             29597..29914
                     /locus_tag="ON488_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCR3231062.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            30158..31768
                     /locus_tag="ON488_000850"
     CDS             30158..31768
                     /locus_tag="ON488_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCR3231063.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            31925..32773
                     /locus_tag="ON488_000851"
     CDS             31925..32773
                     /locus_tag="ON488_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCR3231064.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            33004..33483
                     /locus_tag="ON488_000852"
     CDS             33004..33483
                     /locus_tag="ON488_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231065.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            33516..35744
                     /locus_tag="ON488_000853"
     CDS             33516..35744
                     /locus_tag="ON488_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3231066.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            35873..37516
                     /locus_tag="ON488_000854"
     CDS             35873..37516
                     /locus_tag="ON488_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HCR3231067.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(37589..38134)
                     /locus_tag="ON488_000855"
     CDS             complement(37589..38134)
                     /locus_tag="ON488_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HCR3231068.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(38157..38642)
                     /locus_tag="ON488_000856"
     CDS             complement(38157..38642)
                     /locus_tag="ON488_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCR3231069.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(38632..39444)
                     /locus_tag="ON488_000857"
     CDS             complement(38632..39444)
                     /locus_tag="ON488_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HCR3231070.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(39583..>40694)
                     /locus_tag="ON488_000858"
     CDS             complement(39583..>40694)
                     /locus_tag="ON488_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCR3231071.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        13507 a         7382 c         7962 g        11843 t
ORIGIN      
        1 aacatatagg tagaatctct actatcttat ttcttgcata caaaaaaatc aaggagtgag
       61 agagttatga gatattcaac catcttaata tcaacatttg cagccttaag cttatcgctt
      121 actataaatc agacagtcca cacagaggag acagaaacag ccaaatggac agaaaccaag
      181 tgggccaacg tcaatcgaat tacctttcag gatgaatttt catccttcaa ttcaggagtc
      241 gcaaaattaa gaaaaggaca aacagcgacc atcaaagcaa aaattgacta ttcgggagac
      301 ttagcaccta tactacaatc agctgttaca tttgagaatg ttgatcccac tttgtcgatt
      361 ggctatgacg agaacacttt gactatccaa cacaagcaag cgatatttac cttcaccgtt
      421 acattaaatc aggacttgtt aaaaccagcg ctttttactg tcaaggtatc agatggacta
      481 ccgaacgatc atcatttaac gccgtatagt cagcggcaga caattgagca agattcagcc
      541 atcgactcag gaggagatct tgttgaagaa ccaacagata aaccagaaaa tgaaaataag
      601 ccagaagtac cgcctacaga aaatccagac ggagaacaga aaccggaaat agaacctgga
      661 gaagaacccg atacagaaac tcaaccagag ccagacaata aatcaaaacc tgaaataacc
      721 cctggagaaa aaccagatgt aactccagaa ccagatacgg attctggaaa ccaaacagta
      781 ccggaaacaa atccagacac agataatgaa actgaaaatc cagaaaaacc agaggtagat
      841 ccagaagaaa aaccagatgt gactccagaa ccagatacgg acgcaagaga ccaaggaata
      901 ccagaaaaaa taaacaaaaa aacaattcaa gaggatggaa aaaaagagag taaaaaatca
      961 aatctagcaa ttctaaaaat aaatgaagag cagctgaata aaaaatcacg aatatttgat
     1021 agcgcccaat cagctgaaac cttaaaaagt agcaaggata caacctttgc tgtcctgaaa
     1081 cgaaaaataa acagctacca aaatccggag agtcacaaaa caaagttata ctgtggagcg
     1141 gaatcattct attaagtata gcaacaatgc tttctgcaaa aagatttaaa caaaacagat
     1201 ctctctaaca tttgaataat gtctgtgaac gcatttttca aataaaaaga aatatccaga
     1261 aaatgacccc aaaataccag attgaaatct gatatttggg gtcgttcata ctttatcttt
     1321 cttcatattt attttaaggg atatctgttt cttttggaag atggttcggg atctttttca
     1381 ctttcaatac atctaaaaag aaggtaaaga tcggaatgcc gacaatcaag ccccaaacgc
     1441 caaagaaccg ttcgctaaca agtaagacca caaatgtata aaaaatcggc agttctgttt
     1501 tgctggacat caacttcgga ttcagcacat aagactcaat tagatggaca atcaaaatcg
     1561 taatcaggat ataaacaaca tctcggatgc ctccttggga ataagctatg aaaaatagag
     1621 gaatacaaga aatgataaca cctgctactg ggatcagact taaaatgaaa atcatgatcg
     1681 ctaaactcag cagctgatga aagccaaata cagccaaggc gattgtagtg agcaacgtat
     1741 ttaaaagagc gacaacaaat tgagcttcta ataccaaacc aaatgtattg acaaacttat
     1801 cggcaaaata gtaaatatct tgaaagaacc aagaaaattc actttttaaa aacaatcttg
     1861 agaatacaat tgtttttttc ttttcaatca taaaaaagaa acttaagatg aatgacatag
     1921 caaacgccac tgccattttt cctatatcct gtaaatagcc aagcgcaatc gaagcgccat
     1981 tttgaagctg ttcaaaaaaa tcgtttcgct caatataagt atggatatat tgtaaaacag
     2041 gatctgcatc ttttggctga tgctcgtaaa aattaataac ggactggatc atgtcaaatg
     2101 tttgatgaat aagcatcggg atatactttg tgaatgccag atagataagg taaacgatca
     2161 gtgtataaat catgatagct aaaacacctg tagggattcg gacaaatcgc tgaatgattt
     2221 gaacaagatg aatcatcaaa taagtaaaga taaatgtgag caaaatggtt gtaatcatac
     2281 ttctaactaa gaaaagaaca aaaacgacaa ataataaaac agtgagacgg cgtatttttt
     2341 cattcgccaa aaaacgctga taaacggtca aatcgacaac ctccaaataa caaaaaataa
     2401 acacgttatt cattatatga tggaatatga aaataagaaa gagcaaaaag aaaaaccgct
     2461 aaatgacgtt atcttatgag ttggttttcc tcataaaatc gttcatctag cagtttcagc
     2521 cctttttctg gtcttgatga aaattatcta gcatttttcg ggtcagatgt tgcagtgtat
     2581 ccaattcttc ctgttcaagt ggaagataag acttgatctt ttgtggaata ccttctgctt
     2641 gtttttgcaa cgcagcacct tgagcagtca gcgtaacatt tacgattctt tcatcacccg
     2701 tttcacgctg acgattaata taattttttt ctgctaactt ttttagtaag ggagtcagcg
     2761 taccagaatc cagacacaaa tcatttccta gctctttcac tgaagtcttt ttcttttccc
     2821 ataaaactaa catcacaaga tactgggtat aggtaagatt cagcggcttg aggaggggag
     2881 tgtagtgtct aatgatttct ttagaggcgg catataaagg aaaacatact tgattaacta
     2941 aatatagatc ttccattttt ccacctccgc tgttttacta tagtgtatca tagcggattt
     3001 acacaaaaaa gtctattcac taactgcttt cagagtaact tctatatttc cagctgtagc
     3061 ttttgaatac ggacacactt tatgcgctgc ctctaataat tcttgcgttt cttccagaga
     3121 aagaccttcg atagatcctt caatctctac acctaagaca aagctcgttt cactttctga
     3181 ataaagggaa acttgtgcac tgacagtaga agccccagag atattttttt gctgtttgat
     3241 caattctaat gcactgttaa aacatgcact gaaaccagct gcaaacaatt gttcagggtt
     3301 ggttgcattt tcgacgcgtt taccaggagc tgcaatattc aattcgaatg tacgatcggg
     3361 attatgcact tctccagagc gtccgcctgt gttgatcatt ttcgtagaat acattttttt
     3421 cataaaatta ccacctttaa ttatatttta tacaattgaa ttttacacaa tataattgtg
     3481 gaaagcaaag aaatggattg gcataagata aataagagaa agcacatgaa acagacgcgc
     3541 tttctcgaat agcaaacata tacaaaaaat atcagagaca aaaaataatc tcatcataaa
     3601 cattacatat atttctcaaa aagttgtttt ctttcttcaa aaattacttc acgatggacc
     3661 tgatgaagca tccataaata accaaaagga tctctgaaca ttgagttagt cacaccaaag
     3721 tccatcattt ctgtcatttc ttgaatctct acacagccat ttcgtaatgc tttattatgt
     3781 gtgtcctcga tatcagagac gatgatattg aaccagatcg tatttggatg ttcagcagta
     3841 ggagcagtca aaccaagaga cgtgttttca tccagcatat ggaatctcgt accatacaag
     3901 gtaaaaatga cttcattatt gcctctaggg taatctgttg cctcaatcag ttgtatttca
     3961 tcaaagattg tttgatacag ttctagtgct ttcaaactat catttaatac aaaatcgatt
     4021 tccgttcctt tatgcataaa gatctcctct ccttttcagt cgaacagtta ctagattctt
     4081 ttattatacc agctaaagaa aacgcattca aaaaaatagc ggatttactt accaactcat
     4141 tcgattggat gataagtaaa tccgcgtccc attacttctg ctacgctgct gacaatgaca
     4201 aaggcacttg gatcgatttc ttctatcaat ggtttcattc gggaaaattc atgatcagtc
     4261 acaacgatca ataaaacctc ttttgacttt cgattatacc cgccttttgc ctctagcagg
     4321 gtaaggccac gtccaatctc agcacttaag cgaaggcgga tgtcttccaa ataatgttca
     4381 ctcatgacca taacagattt ctttcgattg atacctgttt cgatataagt catgacaatt
     4441 gaagtgattg caatagataa aatagcataa agaaactctt ctattccaaa aataaacaga
     4501 ttaagagaaa caacgaatgc gtctgtaaaa aataagccaa tcgaagtatt caagtggaaa
     4561 tattttttaa aaatgagggg agggatcgtc gtaccgccgc tagaagagtt gtttttatat
     4621 aaaatcgcaa ctcctaaagc aaaaatcgca cttccaaaaa tgacagacaa caaccgatct
     4681 gaagtaatca ttgtttctgg aactattgca atgattaaag gaaaaaccaa gcttccgaaa
     4741 agtactttaa aaaagggttt tttacctaaa aatagaagag ctagtaccaa cataacgata
     4801 ttcaacacta aaataactat agctcggtca aagcctaaag cagcttccag taatattcct
     4861 agaccgctga cacctccagc agcaatatga tgaggcccta aaaacatatt gatagcgact
     4921 cctaatatga agagggcaaa aataatctta atgtatgtcc atataaattg tctcgtttct
     4981 ttcatttatt cacttcctta attcattaat aatactctta tcttattata acttactttt
     5041 caccttaagt taactttaat taataaaaaa attaggctag tctaaattat tatgtttcat
     5101 tcttctagaa tatacttcta cgccaaaaac tgttaaaaaa cttttacttt agaaaattgg
     5161 agaaattgat cgcttaagat aaattcagga cactaaatag tacaggaagt agactaaaac
     5221 ttttaaaagt tttaagtcta tctatttggc aagtttaaaa aataaaaatt cggtatcaaa
     5281 aaactgttac cgataacatt tttgaaagcg ttgtcttttg cttctctatc acttatagtg
     5341 atgacgtcat attaaaacac aaggaggaaa tcaatggata cagctgcaat ttatcatcga
     5401 ccggaaagtg aatatgcatt tctatatacg aatacaagat ttcgtattcg gcttcgtact
     5461 aggaaaaatg atatcaaaaa agtatatgtg ctatgtggag atccatatac cataacaact
     5521 gaaaaatggt atcaaaaaca acgaccaatg aaaaaatgtc taagtaccaa tgttcatgat
     5581 tattgggaaa ttgaagtgac gagcgaaaca agtcgcttac agtatgcgtt ccatgttgtt
     5641 ggggaagata acacggactg tttttacggt gatcaaggaa tttttcctta tcgagaaaat
     5701 gtgattactg aaccaaattt ttattttcga ataccttatt ttcatcaaat cgatcgattc
     5761 actattccag aatgggtaaa agaaacagta tggtatcaaa tttttcccga aagatttgca
     5821 aacggggaca aagcaaatga ccccgaacac actttacctt ggggaagtaa agatccagac
     5881 cgagaagact ttttcggggg agatttgcaa ggtgtgatgg atcatttgga ttacttgacg
     5941 gaccttggca tcaatggcat ctatttttgt cccatattta aagccacatc caatcataaa
     6001 tacgatacga ttgattatta tgaggtggat cccgcttttg gcgataaaaa acttttaaaa
     6061 aacttgattg atgaagcaca taaaagaggg atacgtatca tgttcgatgc tgtattcaat
     6121 catatgggtg tccattcacc acagtggcaa gacgttctca aaaacggaga aaaatcgatc
     6181 tataaagact ggttccacat ccgttttttc ccagtagatt cttatcagat gactgactta
     6241 ccagaaactg ctgaaaatat cccatatgat acttttgctt ttactccatt catgccgaaa
     6301 ctaaatacag caaatccaga agtgcaaaaa tatttgctgg atatcgcaac ttattggata
     6361 aaagaattcg atattgatgg atggcgtctt gatgttgcta atgaagtcga tcatcatttt
     6421 tggaaaaaat tcagagaagc agttacagaa atcaaaccag acatctatat ccttggagag
     6481 atttggcatt cctctcaagc ttggctgcaa ggggatgaat tccatgcagt gatgaattat
     6541 gcatttacag attcgattaa agattatttt gcaaaaaaga aaatcacagc ttcacaaatg
     6601 gtcagtggaa tgaatcatca gcaaatgctt tacagagatc aggtgaacga aggaacattc
     6661 aacttattag attctcatga tactgccagg atcttgaccc tttgccaagg taacaaagaa
     6721 ttgatgaagt ctgtgatggc ctttatgttt cttcaaaaag ggtctccttg tatctattac
     6781 gggacagaaa tagggatgac tggtgaagat gacccggatt gccgcaaatg tatgatatgg
     6841 gagaaggagg aacaagatct agagctattc ggttttataa aagaacttgt ttctctaagg
     6901 aaacagttgt ctaagattat ttctgaaggt tctactcagt ggctaatagt aaatgatcgt
     6961 gaagataagc tctatttcac acggaaacta gagggacaga tcatctatgt ttactttaat
     7021 cagtcaaaag aaccttgggt agtagaacag gaaaatgagg tgattcttag tcaaaattgt
     7081 cagttgttag aagacgggaa agcagagata cgacaatacg gatttttgat catgtgttga
     7141 aaactgttac cggtaacaac aagaaagcgt ttgcaaatga agatttgtgc ccattataat
     7201 aagggtgtaa cagcacgttg aatacaaagg aggaaatgaa gatgaaaaaa agaagtgtga
     7261 aacagttggg tttagggtta atctctttag gaatcttagg cggattagcg gcttgtggca
     7321 atggtaactc ttcagcagaa ggggaagccg atgaaggaaa aacgttaaca gtttccgttg
     7381 attctggata taaagattat ataaacgaaa taaaaaacac tttcgaaaaa gaaaacgatg
     7441 tgaaaatcaa gctagtagaa aaggacatgt tcgatcagtt ggaatcatta gcgttagatg
     7501 ggcctgctgg aaagggacct gacgttatga tggcagcata tgaccggatc ggtgcgttag
     7561 gacagcaagg acatctggcg gaagtaaaac tgggaaatga agcagcttac gatgaaacag
     7621 acaaagccca agtgacttat gatggaaaaa tctacggaga acctgcagta atcgagaccc
     7681 ttgttttgta ctataacaaa gatttagtcg atacagcacc atcaacgttt aaagatttgg
     7741 agaatctatc caaagacagt cgttttgctt ttgagtcaga agcaggaaaa aatacaggat
     7801 ttttagctaa atggactgac ttttattatt cctatggttt aattgcaggt tacggtggct
     7861 atgtatttgg tgatgatggc acaaatcctt cagatatcgg tttgaataat gcaggtgctg
     7921 tagaaggaat ctcttatgca acagattggt tcaaaaatgt ttggccaaag ggaatgcaag
     7981 acataaaaag tgcaggagac ttcgccagcc agcaattcat gtccaataaa actgcagcaa
     8041 tcattgacgg tccatggcaa gcgcaaacat acaaagaaaa caatatcaat tatggtgtag
     8101 ccaaaattcc tactctaaat aatggacagc cttatcaacc gtttggcgga ggaaaaggat
     8161 gggtagtcag caattatgct aaaaacaaag acctctctca aaaatggctt gattatgtaa
     8221 cgaatcagga aaatcaagaa aaattctttg aaatggtaaa tgaaatccct gcaaaccaac
     8281 aagctaggga aacagcaaag gctaaaaacg atgaattaac aacagctgtg attgaacaat
     8341 atgaaacagc tcaagcgatg ccaaacatcc cagaaatggg cgaagtttgg acaggtgcag
     8401 aaaacttgat gttcgatgca gcatcaggtt caaaaacacc aaaagaatcc gcagatgaag
     8461 cagtaaaaac aatcagtgaa gccatagaac aaaaatactg attaaaatga taaccgtcca
     8521 tttttataaa aaatggaaca ggtgcttcag ataaaagtgg caagagcgag atggaaaatt
     8581 atcttgctct tgttgccatt atcttaaaag cagtttgcgg tttagcaagt ttagaggggg
     8641 cattcagatg cagcaagata aaacaagcaa tatcaacgaa aaaaaaatca cgctttgttc
     8701 acttattcca gggatggggc agtttgtaaa tggccaagct tttaaaggta tcgttttttt
     8761 cgccatattc gtcctattca ttggtcagat gcttctgggc ggatttcatg cattggtagg
     8821 attggttact ttgggaagta taccaatgga agatcattca ttatttattt tgattgaagg
     8881 cactttgcaa ttcatcatta caatcatttt cttgattttt tacggtttga atcttttaga
     8941 cgcttatcga gtagcgaaga tgcgtcaaga gggcaaaaaa atcaatcgga cgatgaagga
     9001 agtcatacat aatataggtg atgaaggttt tccttatcta ttgacacttc ccgcttatct
     9061 tctcatgatt tttacgatca ttttcccagt cctagttaca ttgttcactg catttactaa
     9121 ttatgacttc aatcatattc caccagccag tttaattgat tgggtagggg ctaaaaactt
     9181 ttttagtatc ttctttttaa gctcatatcg taatactttt tttgcagtct tttcgtggac
     9241 cgtgatttgg actttatgtg caacaacttt gcaaatcacc cttggtattc tcacagcggt
     9301 tgttgctcac cagaaattta ttaaattcaa acgtattttc ggtatcattt tcttattacc
     9361 atgggcggtc ccagctttta ttactatcat gagtttttcg aatatattca acgatagcgt
     9421 aggtgccatc aatactcaag tgattccttt cataaaccag cttccttttg tagatatcag
     9481 tgcaatctct tggaaaacgg acccgaactg gacgaaagta gcaattatct tagtgcaggg
     9541 ctggttagga tttccctata tctatgtgat ggttacagga atcttacaat cgatttcaga
     9601 agacttatat gaagcagcaa aaatcgacgg agcaaatgca tggcagcgct tttcaaacat
     9661 cacgcttcct gctgtcttcc tagtggcagc gccaacattt attacacagt atacggggaa
     9721 tttcaataat ttctccatga tctatctgtt taacaatggc ggtcccggaa gcgtaggcgg
     9781 aggagctggt tctactgata ttcttatttc ctggatctat aaacttacga ctggaacttc
     9841 tccgcagtat tctatggctt cagcaatcac gttgattatc tccgtcatcg ttatctgtgt
     9901 gtcattgctg gtatttaaaa agacaaatgc gttcaatatg ggggattaac aatgaaaaaa
     9961 tttcattcga gtgctcgatt ccaaaaacga ctttctcact tttttactta cttttttctt
    10021 ttaatactgt cagtcattat catctatccg cttttgatca cagcaagtac tgccttcaag
    10081 tcaggaaata ttgcagcttt tagtttagat ctttcaagtg actggacttt aggaaacttt
    10141 actcggctat tcagtgaaac actttacggg acttggtata aaaatacatt gatcatttct
    10201 gtcctaacaa tgatcgtaca agtgactgta gtaactttgg cgggctatac ttatagtcgc
    10261 tatcgtttta tcggccgcaa atcaagtttg atgttctttt tagtgattca gatggtaccg
    10321 actatggcag cattgactgc cttttatgtc atggctttct tattagaagc gctcgataag
    10381 tactggttct tgacaatgat ctatataggc ggtggaattc caatgaatac ttggctgatg
    10441 aaaggatact ttgacactgt accaatagat ttagatgaat ctgctaaact tgatggggca
    10501 gggcatttca ggattttttt ccagattgta ttaccgcttg tcaaaccgat gctcgccgtt
    10561 caagcattat gggcttttat gggacctttt ggggatttca tgttagctaa gttcctgctt
    10621 cgaacacctg aaaatcagac tgttgctgtc ggcttacaaa catttatttc tgatgtgaca
    10681 aaccaaagag tctctctttt tgctgctggg gcaattttga ttgcactacc gatttgtcta
    10741 ttattcttct ttttacaaaa gaactttgtt accggcctga catctggcgg aacaaaagga
    10801 taggagcaga gtatcatgca aacatttccg ttaaactatt tttccgcatt acgtacgcca
    10861 actcaagtgt ttgcgggacg caaactatta tcatggccta aatttttctt gatatttgta
    10921 tttttagttt ccttgatggt catgcctgtg actctttttt atgccaatca gatccaagcg
    10981 attccattag aacaatttct atccgttcat tcgctgatcg atgaacaagg aacccaaaaa
    11041 ttttctgaac ttgaattatc tgaaactggg ttacaagcat cgcaacaaac gatagctgtg
    11101 acccctgaaa ttttggtagg tgtgtcttta tctgagaaac aacaatccga tcatggaact
    11161 tttattgatt ttgagaagga acaatgggtg atccaacaaa aggataaatc tggtatacgc
    11221 cgctatacga tgaattatag cccatctttc caaccagatt ctgtacgtac gcccgaagat
    11281 ttccaacgat ttttagaaag agaattttat gccagtaatc gtccaacaat cattttatct
    11341 tatagtttaa gtcttggtct tgtcctattt gtcatgacga gtctcatttt attcggggct
    11401 tcctttttct tgtggatgac aagaaaaagc caactttcat ccattcatac attcaaagag
    11461 agtgcaaatt tgatgctgaa tgttatggga ataggttcca tggcagcagc agttgtaggg
    11521 tttatccact ttgactttat cttgatgcta agtgtccaaa caacgataac tgtcttgctg
    11581 cttttatggg tttttgtcaa aacaagattc aaagataagc gtgtcgaatg acaagtttaa
    11641 gcgatttatg cgacaatgaa tgtgaaaaaa atgaaaaata aagtagtttt tgaaaaattt
    11701 ctgaaaaaat taaacttctt agttgattct tttctttttt agtattaacg taatagggta
    11761 gtttttttaa ggaggaaaat catgttagag aaaactttat acaatcaatt attttcacgt
    11821 tctttctcgc tccctgtcga agtaaattat tgggacggta caacgaaaca atacggagat
    11881 acggacactc ctccccaaat caaaatcaat atccatgaag aaatcccaat gaaagagatt
    11941 acaagtaacg catctttggc actaggagaa gcctatatgg atcatcgaat cgagatcgag
    12001 ggaagtatcc aagcattgat caacgatgct tatcagcaag caaacagctt tttacgagga
    12061 aaagattatc taaaatggct gccaaagaaa gaaaaacata cgaaacaaaa aaacaaagaa
    12121 gatatccatg cgcattatga cttaggtaac gacttttata aactttggct agatccaact
    12181 ttgacttatt cttgtgctta tttcaataca cctgaagata cgttggaaca agcacaaatc
    12241 aataaagtcc atcatatctt agacaaactc tttatcaaag aaggcgaaac gttgcttgat
    12301 atcggttgtg gctggggaac attgatgttc actgctacca aagagtataa tgtcaaggca
    12361 actgggatca cactaagtga agaacaatac gatttgatta ccaaaagaat aaaagaagaa
    12421 catttagaag ataaatgccg tgtattatta atggattacc gcgaactaaa aggcgaaacg
    12481 tttgatcata tcacaagtgt aggtatgttc gaacatgtag gttctgaaaa tcttgaaggt
    12541 tatttcaaag tggtaaaaga tttattgaaa ccaaaaggaa cagctttgat ccatggaatc
    12601 agccgacaac aaggcggtgc gacaaatgct tggatcaata aatatatttt ccctggcggt
    12661 tatgtccctg gtgttactga attagttgat aatattacaa aaaacgattt gcaactgatt
    12721 gatttggaaa gcttacgtcg tgactaccaa ttgacattag aacattggac aaagaatttt
    12781 catcaagtcc aagatcaagt cacgaaagaa atgggtgatt ccttctatcg aatgtgggat
    12841 ctatatttac aagcttgtgc agcttcattt gaatcaagta atatcgatgt gattcaatat
    12901 ttgcttgttc aacctggaaa caatgacatc ccaatgcatc gtgcataatt gaggcaaaag
    12961 tactgtttaa agactattta aaaagaagct aagttttatg atgctccaga agtgaacttt
    13021 tttgtctaac ttctaggatt gtctctaaag cttagtttct ttttctttat attttcataa
    13081 taaaagtttg gttctttaat ttttaaacat gacagaaaat tttttcttcg ttatacttgt
    13141 aatagaatac tattttataa caaaggggat cgaatcaatg aaaaaaactg ttatttatac
    13201 tagtttattt gcagctttgt ttttagctgc ttgtcaatca aataccaatc aaggcacatc
    13261 tgggaatacg tcttccagta gcgaacagcg ctcttcacag gtatcggact cctcaacaaa
    13321 agcaagcaca tcttcgtcta gccagacaaa aagttctagt gaagcaagta ctcagtcaga
    13381 tatcaaagtg tctgcagctc gtgcgatcga attgttccaa gataaatacc cagatactgc
    13441 aattactagt ttggaattag atagtgattg gggatcttac ttctacaaga tagaaggtgt
    13501 cgatgatcaa aaagaatacg aagcaagaat tgatgctcaa aatgaaaaaa tggagacaga
    13561 gaatccagaa actctagatc gagatgaaca aaatggtcaa aagaaaaaag aagatggtct
    13621 ggatgttgat aaattgatca cgattgagga agcagcaaaa atcgccgtcg acaaagtagg
    13681 aagcggtacg gcaacagatt gggatttgga taaagattta ggtactactt attgggaagt
    13741 caaagtaaaa gacggcaatc aaagtacatc agtcaagatc aatagccaaa caggcgaagt
    13801 actgtcaact gaacaagatg attaagaatt tcttcggaaa acaagagttg atttttcttt
    13861 tagtcatgat acactagaca aaataacttg tttgaaggag cgatttactt gagtttagaa
    13921 acgacctttg ccaatcatat ctttgccaat cctttgatga atgcatctgg tgtccactgc
    13981 atgactaccc aggaattaga tgaactggct cattcagaag caggagcatt tatcactaag
    14041 agctgtacga tcaatgaacg aaaaggaaat cccgaaccac gctattttga tgttccttta
    14101 gggagtatca attctatggg acttccaaac ttaggttttt cttattatct agagtatgct
    14161 cttgcgtatg aaaaagtgca ggaaaaccaa aatcaaccgt tatttttttc cattgccggg
    14221 atgagtgtcc aggaaaactt ggaaatgctt gagaaaatag aaaaaagtgg gtttaatggg
    14281 atcactgaat taaatttatc ttgtcccaat gtgcctggaa aaccacaact agcttacgat
    14341 tttgaggcca cttatgaaac actgaaagaa gtattcagca tcttttctaa gccgctagga
    14401 atcaaattgc ctccttattt tgattttgct cattttgatc agatggctga tatcttgaat
    14461 cagtttccat tgacctatgt caatgctatc aacagtgtgg gcaatggttt gtatatcgat
    14521 acagaacaag aagcagtagt catcaaacca aaagaagggt tcggcggcat tggcggagag
    14581 tatatcaagc cgactgcttt ggcgaatgtt cgcgcttttt atacacgttt gaaaccagaa
    14641 atccaaatca ttggtacagg tgggattcgg acaggacaag atgcatttga acatctgcta
    14701 tgtggcgcaa gcatgttaca gattggtacc gagcttcata aagaagggcc ggaaattttt
    14761 tctagaatca taaaagaatt aacgcagatt atgtcagaaa aaggatatac gtcaattgac
    14821 gaatttaaag gcaaattacg caccatttca tagcaaagag acgaaggtca tgattgatct
    14881 tcgtcttttt ttataaaaaa cactcgtctg ttcattcctg tgcaagcgta ctcattgtat
    14941 gttagacgaa cttgtgggaa aataacagag gcaaaaagga ggataatatg aatgatgcaa
    15001 cagaattagc aaaagagctt aaagaaaaag aatttagttt tcaagaacta gttacggata
    15061 tacagaaaaa aataaagaag caaaatcatg aattgaatgc gtttgtcgcg cttgaaccat
    15121 tcgagagtaa ttcccacgag ctattgattc cccagtcaga aaaagggcca ttggctggta
    15181 tcccatttcc tttaaaaatg ctcggtcaag aaaaaaaggg atggctagct acttcaggat
    15241 ctcgtttatt tgaaacacac cgagcttctc atacatctaa ttatgtgcgg caagcagaag
    15301 cgataggtct agttcctttt ggacaaacca atgcgccaga gtttggtttc aaaaatatta
    15361 cagacccagt catctatggc ccagcaagaa acccttggaa ccttgaatgt acaccgggcg
    15421 gatcaagtgg aggagctgct gctgcagttt catcaggaat cgttccttta gctggtgcta
    15481 gtgatggcgg tggttctatt agaatacccg cttcgttttg cggattgatt gggctgaaac
    15541 cttcgcgagg gacgatgcca gttggtccat atgcttggag aggatggcaa ggagctgcta
    15601 ttgatttcgg cttgacagtt tctatgagag acacggaggc tttattttat gggatgagaa
    15661 gtatccattc cggtgcgcca tatcaagtat cgccagttga gtggcaaaca catccaagaa
    15721 aaaaacggtt gaagatagct ttttgtgttg attcaccgat ccactcacag attagtgaag
    15781 aggcagtact tgctgtaaaa aaagctgtag atttccttgg aaaagaaggg catgatttga
    15841 cagagattcc ttacccacta gatggtcgta aactgatcac gtcttattat cagatgaatg
    15901 gcgcagaaac agcagcaatg atccgctcga ttgaaacagg catccagcga gctgtcagaa
    15961 aagaagaact tgaacccatt tcttggactt tgttccaata tggtcagaag ctctctgccg
    16021 ctacttacat cgattctctg catgtatggg atgaagcagc aattgtcatg gaaaacctac
    16081 atcaagaata cgatctattc ctttcaccaa cgactgcatt taccgcccct aaaatcagcg
    16141 aagatttgca aagtgatgcg ataagagcac agatggaaca catcagtgat tgttctgaag
    16201 tagaaggttt agacgttgtt tcttccatgt ttgaggagag cttgaagatc acaccttata
    16261 cacagttggc taatctgact ggacaaccag caatcagctt gcctactcat ttgacaaaag
    16321 aaaacatgcc tctaggaatc caatttatgg ctgccagagg aagagaagat ttgctatttc
    16381 aaatcggcta tctatttgaa gcaaatcatc agttccattt accaaatcca tggaaatagc
    16441 agaaacaagg agaagaagaa tgaagaaaaa aagattgttt gctctaataa ctagtgcctt
    16501 ttttatttta agcgcttgcg gtacagctgc cgctaatcag gaagataaca gctggagtaa
    16561 tgtagaaaaa aagaaagaat tagtagtagc gacttctggc acactgtttc ccgcatctta
    16621 ttataatgat caaaatgaat tagttggtta tgatgtagat ttggcaaaag aggtggctaa
    16681 acggttaaat gtcaaaatct cctttaaaga atacaacgtg gatggacaaa tcacttctgt
    16741 ttcaaaaaga gaatcagatt ttgctgcgaa cgattttggt atcacaaaag aaagagaaaa
    16801 aaaattctcc ctttcagaga ctttcaaata ttcatttgac agtatgatcg tacgaaaaaa
    16861 agatgattca ggaatccact cacttgaaga tcttaaaggg aaaaaagcag ctggcgaacc
    16921 caatactagc tatatgcgtt tagcggaaaa acacggagct aaattagtca catatgacaa
    16981 tgccacgaat gatcagtatt taagcgatgt agcaaatggt cgaacagatg ttattctaaa
    17041 tgattattat ctgcagaaaa tggccgtatc tgctttacca gatatccctg taaaaatact
    17101 ggagaacgtt tatttcaatg aaaacgaaag tggtttttta ttgaaagaag gaaatgatgc
    17161 tctgaaaaag aaaatcgatg gcgtattaaa agagatgaaa gaagatggga cgacaaagaa
    17221 aatatctgaa aaatattttc aaactgatgt ttcagtcaaa ccgaaagaaa cgatggctga
    17281 gtcggtgagt gagtgatgta ctttcctcta attgattttt ccctcatgtg gacttcactt
    17341 cctttcgtac tgcaaggctt ggtatacaca ttagggattg gcttcgtgtc gtttctttta
    17401 ggaaatctgg tagggttgct tttgacagtt ttaggtcttt tggattggct gcctctgaat
    17461 gtatttattc gtttttattt atcgttcttt agaggcattc ccgcactagt cctgctgttt
    17521 ctgttatatt ttgggttacc ttatcaatta agtgccttaa cggcttcagt catctgcttt
    17581 acgattacca gcagtgcatt tattggtgaa atctatcgag gatcactagc aggcgtttct
    17641 tcaggtcagt gggacgctgg tttagcttct ggtttttctt tctttggggt attgaaatat
    17701 atcgttttgc cgcaagcttt tcgaatctca gtaccggcac tcagtaacgt agctatggat
    17761 ctagtgaaag gtacttcgtt agcagcaaca atcacagtgc cagaaatatt tcaaaaagca
    17821 aagatcatag gcggtcggac attcgattat ttttctctct atattttagt tgcactgatt
    17881 tattgggtca tttgtatcgg gatcgaaaaa gtgcaacagt atttagaaaa acgttctatg
    17941 catcagtcaa tctgaaaaat agaaatggtg ctagcgtggc tggcaccatt tctatttttt
    18001 gtttcttgta tattctgcct agtattttaa aaccatttca tgtaaaatgt aaatcgaaaa
    18061 tatgttcgga ggtagaaaac atgaagaccc cgctaaccat cgaaatagaa tcctcgttat
    18121 accaatattg catcgagcaa ggcggcttgg ttgtagaaga agtcacgatg cctgatgacc
    18181 aaggaattgt agatacgctt agctgcttga caaaatttga tggaagccga gaatggcgat
    18241 gctatgagct gaaagtgaca aaagcagatt ttcgctctac agccaaactg tcatttgttg
    18301 gacattataa ttattttgtt ttaccaagta aactatatga agaagtaaaa actgaaatcc
    18361 ctacaggaat aggtgtttta gtgtatcgtc cgtacacggt tgaagaggag atgcctgcct
    18421 ctggtacatt tctgattgcg aaaaaagcag caaagaaaga gcttgctgta ccggaagaag
    18481 ctttgacaaa ccgcttcatg gcttctttat tcagggaagt aagaaaagca aagcaaatgg
    18541 agcgaggcgt aaaatatttt ccaacagatc aattgtacaa agaattgaaa agacgttcag
    18601 aaaatcaaga tccattttct aacgaacgat attatgaacg gtttttagag gaaatagcta
    18661 gtcaggcaat caatgagttg caagaagaag ttatcgcgct tcagcatgat tatgaatatt
    18721 tgaggcaaca acagcagatc cgtcggttgc ctacagagcc attggagtga aaaatatgta
    18781 ctatccttat ttaagaggaa aacaatttga cctattagca ttaaaagaag cactgtcgcg
    18841 aggattgctc tccaataaaa tccaaccagt gatcgaacca gtacgtgatt ccgctacgct
    18901 taaaaatgtg atcgaattat ttcaaaaaaa gcaccatcga atcgctgtga tccaaaatcc
    18961 ccaagtagga caattcaaat tattcgatca gcatgtgcac agttggacag tcaaagaaaa
    19021 tagctctgtc gtccctgcac agatcttaac gccagaaaat ctcagtgaag tactggattc
    19081 acctccagcg tttcttgttt tcgatggaca gcactaccca aaagatacag aggtgtggaa
    19141 acagttggca ggagttgatt cgaaattttt gataccagat actagtcgct ttcgcatctg
    19201 gctgcccgaa aacaaaattg tgatccgtga ctcttttcaa acgagaaagc atgttgaaag
    19261 ttatgcagat aaaacagatg acttttttag tgatgactat ctttttttcc acgcagacgg
    19321 atatattgga ttttctgatt tcacgatcga aggtagccgt tatttcgata aagggttccc
    19381 tagccgagcg cttgctatcc atctaacgta tattgatgct tacggcaata tacgcgtgaa
    19441 acattttgtc tctgacagta acgactctgc taaagaccaa gcattgaagt ttcttgaagc
    19501 aggagataaa atgaaaaaat ggatcatgcg tcaccatcat caactcttga ttacttcagg
    19561 aatgattgaa ttattggctc tttaccagca acaaaaattc cctggactgg gagtgttgaa
    19621 aaagtggtca cttatgcatc atttggaact tattagtcac ctgctagatc atccaaaaga
    19681 ttggcttaaa tattattcaa aagttcagga actatatgaa gtgatccaat gattagataa
    19741 tgtaaatgaa aaaggaatag aaaagaggaa actggatgta tattcggcaa acaaggaaag
    19801 aagaagtaga agaagtggta gaaatcatta atgccgcagc ggatttcatt gcttcgcaag
    19861 gctctcctca atggcaaaac gggcagaaac caacaaaaga aacgattttg aacgatattg
    19921 aaagaaaaga aagctatgta ttaatagtgg aagatcaaat tgctggaaca gctgcattag
    19981 tctcaagcgt ggatcccgtt tacacaaaaa tagatggtag ttggaaagaa tcaactggtc
    20041 cttatttatc gattcatcgt gtcgctttag cagaaagtac tcgaggaaaa aaactagcaa
    20101 aaccgttctt agaacatttg ttgacgattg cagccagcaa aaatatccaa gatatccgta
    20161 tcgatactta tccagctaat gaaccgatgg aaaagaccat ctattctgct ggattcactt
    20221 atcaagggat gattgaattt ccttttgaac acggcgaaag aaaagcatat caaataatca
    20281 tcaattgact ataaaatcat ctgagcaaag ataaagacat taacactact gaaaaaaaca
    20341 atcatatgat agccaagagg ttgtaacaga agtggccagc ttcaaaaaac aagaaagaat
    20401 ttccgaaaat gcttctcaaa tttttgtgga attttagcgt attttacgaa atagctgctt
    20461 tctgaaactc ccttcatcga gaggtcgtga catagctttt gtcacgacct ctcggcttat
    20521 cctacgagta ttattcgata catttatatc aataatcctt tttttatttt atctgcagct
    20581 tcttggaacg ctccatcgtt tgacacgact aaaagtgagg ggatagcttt caaacgtttc
    20641 aactgtgcta aatcttctac ataaaccgcc agtctggctg aaatctgttc agatgaatct
    20701 ccacgttttt tcaggcgcga ttgcaatgtt tctttagaga tcgtaataaa gataggacgg
    20761 actaccgtcc cgaaatactc atataaatgc caaaaaccat ttgctgtcaa aacggcgtaa
    20821 caatttccta ctgtcagttt ctttttaatt tctgctttac tggaaccata tttatgttga
    20881 gcatattggt cccactctgc aaactcattt cccttgatca tctgattgaa tgtattgtca
    20941 gaaacaaaat aataatcctc ttgatctttt tccccaggtc ttggtgatcg attcgtgtaa
    21001 gtaatgatct tttgttccgg ctgaaaaata gcttctgcga gtgaagtttt tccagaacca
    21061 gaaggaccga taaatacata gcaataattc attgtcattt ctcctttgat gattgaacaa
    21121 gtgaaaaagc tttggaaaat atttccaaag cttttaaaag taactttgct tttttgtata
    21181 ttataccagc aagccagtca caatagcact taaaaagctg actaaagtcg ctgttagcaa
    21241 aattttcaat ccgtgttttg cgacaagatt tcctttttct tcatttaatc ccttcatcgc
    21301 accagaaatg atcccgatag aagagaagtt ggcaaatgaa acgaggaaga cagatataat
    21361 tgctgttgta cgctcagtaa aatggaaatt accatttgct aattctgtca tagcaacaaa
    21421 ttcatttgta accagtttag tcgccatgat actaccggca tccactgctt ctttccatgg
    21481 gattccgctg atgaaggcaa gaggggcaaa gatgtaacct aggatctctt ggaaagtgat
    21541 gccgaatatc ccgtggaaga tagcattgat catggcaatc aaagcaacaa aaccgataag
    21601 catagcagca accgtgatcg ccacatggaa accatcaaga atgtattctc ccaacatttg
    21661 gaaaaatgtc tgttctttgt tttcttcaat gatcagctca tcttcttttt cttctaatac
    21721 atagggattt acaattgaag ccagaatata accgccaaat aagttcaaaa caagggcagt
    21781 gatcacatat ttagaatcga tcagtgccat ataagatccg acgatcgaca tagaaactgt
    21841 agacatagcc gatacactca tggtgaacaa acgtttctca gataggaagg gtaattcctt
    21901 ttttatggaa ataaaaactt ccgattgtcc taaaatagca gaagctactc cattataaga
    21961 ttccaatttg cccatcccgt tgattttact taatcctaga ccaacagctt tcataaataa
    22021 tggaagaatc ttgatatagc gtagaatacc gataatagca gaaataaata caattggcat
    22081 caatacggaa agaaagaaag gtgcacttcc tttatttgct acaccggcaa aaacaaagtc
    22141 aacaccttgc ccagcaaaag caagaagatg atcaaacatt tttgccaata cagaaacaac
    22201 cgctgtacca aaagttgtac gtaataatac gaaaccaaga acaagctgta aaacgaacat
    22261 cacaattagt ggtttcaatt tgattgcttt tttgttactg ctgatcaaaa aagcaagccc
    22321 taatgtgaca aataaaccaa taatacctaa taaataactc aaataatcac tcctattcca
    22381 aattccgttt tattttacct gttttgcaaa taaaatacta atctttagtg aaattttcat
    22441 tactttttta gagtgaaacg cattcatttt ccattagaaa ataaagcgaa caaaataaaa
    22501 ggtttaaaaa gtgtaacgtc ttagtaaagt ctataaaaaa acgaaactat cgattaagct
    22561 aatagtttcg ttttcaacat ttataagtaa actttttcta ttggtaatat agattttcgg
    22621 aagggtagac aggtgcgcag gtaatatcga ttcctagttt tttcaatgtt tgttcatcat
    22681 ttttattgac catcacagta gagtgggctt gtgctccctc aagttcagct agtttatcat
    22741 aagcaacttg agcgattgga ttcgttactg cactgattga taaagcgatc aagacttcat
    22801 tgatgcttag tgcatccaaa gaggaatgaa gtgtctttga tttcaatcct tgtattgttt
    22861 caagaactaa tggtgacaat aaaggaatgt catctgcgat atgggctaaa tgttttactg
    22921 catttaagat aactgccgct gacgcatcca tcaatgaact tgtacgcccg gtaatgatga
    22981 cttcatctgg taattcgatt gcaatcacag cagaaggatc ttttgtagga ctttgcgctt
    23041 gaatcttatc tgcatagtca tgggcaggga ctaccacgtt tcggtcttca ggacgtaaac
    23101 cgacttcttc cataatcagt ttgattcgat taactgcttc ttcgtcgatc aatccttttt
    23161 tgaagtcgca ttctgtttgg aaataacgac ggatgatttc ttgtttagag gcttcttgga
    23221 caacggtatc atccacgatc ccaaatccta cacgattcac acccatgtca gtaggagatt
    23281 gataaacaga ttctttacca gtaatttttt caataatacg tttgattaca ggaaatgtct
    23341 caacatcccg attatagttc acagctactt tattgtaggc atcaaagtgg aaggaatcga
    23401 tcatattgac atcttttaga tcgactgtgg ctgcttcata agcaatgttc agcggatgtt
    23461 tcaacggaac attccatact gggaaagttt cgaacttgga gtaaccagct gcatgtcctt
    23521 tttggctttc atgatacagt tggttcaagg aagtagcgag ctttccactt cctgggccag
    23581 gagctgtcac tacaacgatt ggtttagttg tttcaatata ctcatttttt ccaaaaccat
    23641 cttctgagac gattttttct acgttgactg gatagtcttc gatttctgag tgtttataga
    23701 ccttgatgtt tcgtctttct agtttattga taaagacttt cgtggcaggc tgtccactat
    23761 agcgagtgat aacgacactg ttgattaata agccataacc acgtaattca tcgattaacc
    23821 gcaagatatc catatcataa gtaatcccat aatcaccacg gatcttatta cgttcaatat
    23881 ctccagcata gacgcaaatc agtatttcag cttgatcttt caatttttgc agcaatttga
    23941 ttttcgcatc ttcttcaaat cctggaagta cacgtttcgc atgcttgtcg tcaactagct
    24001 tcccaccaaa ttctaaatat aatttgtcat agtggttcac tcgttccaaa atatacgctg
    24061 actgctcttc aatatatttt tctgaatcaa aaccaatttt tttcactagg ttccctcctt
    24121 aagtactaaa gcattttttc atttttttga ggattcgtca actggaagag cgaaattcct
    24181 caaaaaaaca aagaaaatgg tttaaaccaa cttgtctaga tagttattca ttggtatgat
    24241 agtttttgat aaggaaggtg ctacatgaaa aaaagacaga aaaaggaaaa cgcatataaa
    24301 cactatatcc gttcgatttt taccggttat gaaagaatgc ttgaagatcc cgaattggaa
    24361 caattgacgt ttacttatct aaacgaagaa acgcagctaa ctcgtgatga gcatcagcgc
    24421 attcatttca caacaagaga tctgcctagt aaataaaaaa taagataaag gtcatcggat
    24481 tcgattctgt cctatcagat ggaaagacta gttgatcgaa aaaaaggctg taccaaattt
    24541 tggtgcagcc tgttttatgg agcattgccc gctctttttt ataacaattt tttacagaaa
    24601 atggtactat tgaagtatta ataagtgaaa aacagatgag taagaggagg caagtagtat
    24661 gaaagagcca gatacaaatg caaattatga gccagacgaa ctagaggaga cgaatgcgga
    24721 tcaggataca ggacaagaat cgtcttcttt ttacgatatc aaagaaaaag caagcatgaa
    24781 tctttcccaa ttattagaag acttacaggc ttttgaaaaa gctgtccgcg aagaagatat
    24841 ccctgagatc taccgtttat acaatggccg attgaatgaa gaattaaaaa gaagctcaaa
    24901 tgaaaatcac gagatcgatc aattgctgat gcgtaagatc catgatcgtt ttttacagga
    24961 atttcctttt atggaacaag tagaaaacat ctcgccaacg atgagctatt acaaaatcgg
    25021 cacttattac catgatcggc ccacggtcgg tattgatgca agtctgccag aaatttttgt
    25081 tttgcctaag atcgatgaag agtgggagaa atattcccaa ccggagtcaa cggactatga
    25141 caaaaaaatc aatgagctag acgcaaaggt gatcactgct cagacagaaa ttgaacgttt
    25201 agatgaacaa ataaaagaaa tcaatcgaca aatgactgat ttgaacgaca ataaaggatt
    25261 cttgaatcgt aaaaaaatcg aggaagaaat tcaagaatta gagaagaaga agcaagtact
    25321 atctaatgaa aaattaggct ggcttcctta tattgagacg cctgaaacaa tccagcagca
    25381 aaaagaagca ttgaagcaag aagcaagagc agaccagctt cgtgcagcca tcgtagaaaa
    25441 agaacaaagg caaatcagac gctatttcgg tagcaaagag ggattcggtc aagcaatcca
    25501 tgaattcttg atgaattatc ttggcaatga gaatcctaat aatcaatcta atgaaggagg
    25561 ttccgagtat gaatgaacac gatgaagcag aatggacaaa aaatgaagaa caaacagaag
    25621 atcatgaaga aacgaacact tcattggaag aacaaacaag taatcctctg gatgacacag
    25681 aagaaatccc tatgctagag gaaacaaaaa tacacgaaaa agaaaaagta actccgacga
    25741 atacgaatac tgcagaaaac acccatgctt acgaaataac tgaaaatccc gggtatttag
    25801 aaggaaaaga gcaagatcat caagatatcg tcagtttgat tgaaacagcg gaagcagaat
    25861 tagcggattt acgtatgaga aaagatttga tcgaatcaga ttttccacaa ttattagaat
    25921 catatgatcg ttttatattg aatgaagaac caatctccac gatcggaaag acaagcctga
    25981 tcgaatactt cacgtatgaa ttactgaaac cgttgaatga tattggtctg gaacggtcaa
    26041 attcagctta tgacacatgg aaaacaagac atttttcgat caattatacg ttgaatggac
    26101 aaaacgaatt agtcttttcc tttgtattac cgaccatcga tcaacgatac caagtggaat
    26161 cgatgagtct cctaaacgta tcaccagaga caatggaaat caatgtccaa gatgaccggg
    26221 tgctttcttt gatccgacac tggtcagtgg atcgagtatt ctctgcaggg cagatcacga
    26281 tattcaatca caaattgaat caattattag cccatgcaag aacacttggt tttaccgtta
    26341 atcagacatt actagacaat acgaagccac ttcgtttgaa tcttcagagc gaatttgaat
    26401 tgacgaatga agtattggat gatattttta tcgtggcaat gaaaaatcca tcctacgata
    26461 tggaaaagat caacgaaact acttatcaag tacgattaga taaaggacag tctttaacga
    26521 taacaacaaa cgaaaaagat caaacagtct tgtcgatctc atctggagac tacccacgat
    26581 ctgtcattga tttctttatc aattacgaat tcttggtccc attaatggtg agaaagtcct
    26641 gattggataa gttggattac cagatgtcat tcagataatt ctgttccaaa ggacttgcgg
    26701 cagttatcca gaataattgt cacaagtctt ttctgtatgt actaaatgga cgtgaataac
    26761 ttgctgatga aggagggatt tcattaggaa tgtccacaaa taaaatagca cagcttagct
    26821 tattgtctgc tgcttgtgta gcaggtagga tcgcttttca atttattccg aatttccagc
    26881 caatgactgc tattttttta tttatagtac tttacttaag cttaaaagat gcgttaattg
    26941 tcatgagtct ttctattgcg atcagcagtt tttattttgg tgttggacca tgggtcatcg
    27001 gccaatggat cagctatact gttgttctga gtttgttttc aatcgtctgc ttgagaaaaa
    27061 cagtgcaaag gaatctatgg ttaaagggag tctgtttttt tctggcgggc atggtttacg
    27121 gaataggtat gaccgttttt gatacgctgt tatatcgttt gcctcaacct tggatctatt
    27181 accttcaagg ggtgtcgttt gatttgatgc acagtatagg caatgttgtg ttctttcttg
    27241 tttttctgcc agtcgtcaaa cgtttttaca atcattcagg aggaaaaaat gaaaaaaata
    27301 atttatagtt tgcttgcaat gagtgtcagt atactcattt tgacaagttg cagtacaacc
    27361 tatacacaat cggcttccaa ccaaaaggag gaagtaaaaa catcgcaaaa agcaacaatc
    27421 acgttacaag aaaatggtca aaacttttcg gaaaaagaag tgttcttcaa aaaaggcgat
    27481 gatttactga gtattttgaa acgacatttt gaagtcaaag aagataacgg cttcatcact
    27541 tcgcttgaag ggcactcaca ggatgagaaa aatcaactct attggatgtt tactgtggac
    27601 gggaaaagtg ctactactgg tgccaaagag atcaaattga atgatggaca atcggtcatt
    27661 ttcaatttgt ctaaactata agtttcataa aaaactgtta aagggcgaat attgccataa
    27721 ttcagtgagt tcagttgatg aaagaaggaa aataacatgg aaaattttaa aaaaagcgga
    27781 atgttttccg taattgctgc tctaggggct aatattctag ttgctatcag caaatttgtc
    27841 ggctatgcaa tcagtggcag tgccgccatg ctaaacgaaa gcatccacag tatcgttgat
    27901 tgcagcaatc agattttgct gttattcggt gataaacaag ccaataaagg acagagcgag
    27961 ttgcatcaat ttggtgaagg acgagcaaaa tactttttca gtacaatcgt cgcaatgatg
    28021 cttttcttcg gcggtggggc acttggggtg atggaagctt ttgaaaagtt gacgcatcca
    28081 tcccatgaag tgggtaatcc gatcattgtt atagcaatac tgttatttgg tttggtaatc
    28141 gaaggaagtt cgttacgcgt ggcaatgaaa gaaatcaaag aattgaatac tgaaaaactt
    28201 tccacgatgc gctttttgcg cgaaagtcga cacagtgaaa tactgattat ttttacggaa
    28261 gacttgtgtg ctgtaatcgg tttggtcttg gctttagcag gaacaatatt gacttatgca
    28321 accgggattg ctgcatttga tgcgatcagc ggattgctga tcggtttctt gctgatggga
    28381 gccgccattt tcctagcaaa agaattttat agtctgatca tcggtgaaag cgtgacagca
    28441 agcgatttat caaaaatcaa gttagctttt gaacgtcctg agatcagtcg gctgatcgat
    28501 ataaaaacag ttcatttaag tccaacggag attttagttg cagcaaaagc agatatcgtt
    28561 ggtaacaaag agaatgaagc ttactcggtc atcaatgata ttgaaaaaaa tatgcgtcag
    28621 tctcttcctg acaagaagat gtatatatac attgaaacag ataaatatga cccaaattat
    28681 tctcgtaaat aaaacgttta ttcatgaatt gaagcaaaaa tgagaaaaat ataatcttgt
    28741 ttttaaataa aacggctaca atttagcgaa tttatgttac aatgagtcca ctgtttattt
    28801 gttgtaatta aaggagatat tttaatgaac aaaaagaaaa gtgcgccatg gcttcaagct
    28861 ttgcatgcag tgatgccact ttgtataagc tatataccag taggattagc ttgcggagta
    28921 ttgttgcaaa aagttggatt tgatcctctc ttatcaggac tgttatcgat tctggtcttt
    28981 tccggtggcg cgcagttttt agttgcatct atgcttacga cgcaagcatc atttgcaacg
    29041 acattattga tggttttctt tttagaatta cgctatacat tattaggagc aagtcttgcc
    29101 ggttttatga aaaaagaaaa gcggacgttt ttggctgtct tttctcaatc actgaatgat
    29161 gaaaactatg cggtgaacta cttaaagttt tcaactgacc cttcctggaa taaaagaaag
    29221 gctttatatg tcaattggtt ctcaatgact gcatgggccg gtagcaatat gatcggtaat
    29281 tttttcggct cggtgattcg agtagatgct gaccttgtcc attttgcttt gacggccatg
    29341 ttcattttca tgtttatcat gcagatgaaa agcgcactac tgatctttac aggtttattc
    29401 tcaggcgtat taggggtcgt attcatggta ttattccaaa atactttcgg attgattgca
    29461 gcaacagtca ttgcttcatt tgccggattt atgctggaga aggcattcaa aaaagaaaaa
    29521 gctaagaaac taagagaccg cggtaaagat gtcaatgagc cgctcttcaa cttcccggaa
    29581 caggaggcca atcaccatga ctaaactata tttgctactt ttagttgctt gtctgttcat
    29641 cgtggcatat atcccgcgct tgttcccgat gctttatttt actcatcgaa aagtgccatc
    29701 ctggttcagt gactggatga aatatgtacc ggtggcatta tttgcggcgt tagcttttaa
    29761 agatgttttc attactcatg aacatctgga tattgcttgg aatatcaaaa tagctgcaat
    29821 gattctagta gcaggcgtgg cttacaaaac acgttcgatg gcgttgtcag ttttgacagg
    29881 acttgcgtct gtctttttgc tgtctatgct ttaaactgtt ttattttatt aaaaacagag
    29941 attgcgacat aagttgttca aactgatcta tccgaactgc atttgcaaca gtcaattctg
    30001 gatgcaagtt tattcgtagg gataaaaaag attagtgttg gcttatgatg caagctcttt
    30061 tttattttag gaattagaga gggatttgtc cttctatgat tttttgctat aatagggaag
    30121 atgtttattt tatgaaagaa tagttgaggg aatttaaatg aataaaaaat tgatgcaagg
    30181 aacattttgg ctaacctttg ctaatcttct atgtaaagtt ttaggggtag tctatttgat
    30241 tccctggcta agtatgatgg ggaacaatca agatggtatg cttgctacga cattgtataa
    30301 tgttggctat cttccttatg gattgttcct gatgcttggt acagtcggat ttccaaatgc
    30361 gattgcaaaa aaagtagctg tagccacaaa agaaggagat aacgctgctt gtcggctgat
    30421 ttttagaagt acgatcaata tcatgtttgt catcggtatc gcctctgctg cactgatgta
    30481 tttatttgct cctttactag ccggaatcag tccgattgct aacgttaata atgggatact
    30541 agctatcaga agtttatgcc catctttgat tgctatccca attcttagtg caatgagagg
    30601 atatttccaa ggaaaaaatg atctgcggcc ttatggaact tctttgatta tcgaacaggc
    30661 tgtgcgagtg atcgttatct tggctggtac ttattacttg cgcgtattga ctgacggaac
    30721 catattagaa gctgtattga tcagtacagt cgcttctttc ttcggtgggt tagctgcgat
    30781 tatccatatg tatatcgtcg gacgcagaaa agacttcttc gaacttaaag attttttgat
    30841 ttccagccgt tatttcgaaa gagaaaaccg atctgcctct gtctctatca ttcgggaaac
    30901 actaccgttt atttttgtcg gctcagtcat tactatcgtt caaatgatcg accaagtaac
    30961 gatgaaacca ctgcttcact ttttccgtcc agagatcgca gatcagcaac tggaattctt
    31021 attcagccgt gcttctgtca atccaaataa attgacattg atcctgatct ccatggtagg
    31081 aacagtagct ataagcagct tgccaatatt aagcacgatg aagaaaaaag atcggataca
    31141 aatcgaaaaa acagtaggag atagtttttc gattgcgtta ttgattcttc ttccttcatt
    31201 gactggaatg tctttattag ctggaccact atacacattg ttttttggct atgatcctga
    31261 aagtgtcgga tatttccaaa tggctttgct agcttctttg tttttctctt tattcacgat
    31321 cctatctacg atgcttcaat ctttgaatca ccatcgtttt gcgatccgat taactgtaga
    31381 agcaattatc ctgaaagtca tcttccaagt aatcggatta ggattagttg gcggatacgg
    31441 gatgagctta tcaaatggct tagcattcgg tattgtcttt gttcgcggct atcactttat
    31501 gtgcaaagaa taccgaatag cacctttagc aaagatcagc aattttttct taaaaacttt
    31561 ccgctccacc ctgattatgc ttgcagtatg ttttgccgtt ttctttttgc tgaatcagcg
    31621 attgtcaatg gaatcaaaaa gctatgcaat gatttattgt gtggctgtag gaagtattgg
    31681 cggcttagta tttttatttt ctcaattcgg aaaaaatggg tttcgaatgt tgaaaaatgt
    31741 taaacatcat agcagaagca aagaataggt taactaatcg ttttttgctg tcacttgaaa
    31801 aacggcaact cgtatgatta cgcttgtcgt ttttctattt tccaatttta gtttcatatc
    31861 taatcttact tatgatatag ttataaggtc tggaaaaatt ctttgaaacg aggaaattaa
    31921 acacatgaaa cttgcagtag ttacagatag ttcggcatat ctgccggaac gtatcaagaa
    31981 ccatcccgac ttattcgtta ttccaatccc tttgattatg gatgggaaaa tttataacga
    32041 aggaatcgat atcgaagcgg atgaatatta tggactttta aaaaacagta aagattttcc
    32101 tactacttca caacctgtcg taggggaagt tttgggttta tatgaggaat tgaaagagaa
    32161 agggtatgac acgattttaa gtatccatct ttcttcaggg atttctggct ttgtcaacac
    32221 attatttgcg atgaaagatg acatcagcgg agtaacggtc attccttatg actctaagat
    32281 cactagtatg ccgatgggac acatggtaga agctgcctta gacttaaatg atgaaggtca
    32341 gtcccttgat gaaatacttg cacatatcga tcgaatccga gataatacct acgcttatct
    32401 gattgtagat gatttgaaca atttagtacg aggaggacgt ttgacaaatg gtgcagcgct
    32461 gattggcagc ttattaaaaa tcaaaccgat cctgacattt tctgaaggga aaattgtttt
    32521 attcgaaaaa atccgttcaa gtaaaaaagc atttgctcga gctgaagaaa ttattggtag
    32581 aagaaataac gaaatacaac cgccagtcaa actttacgtg atacatgcaa ataatttaga
    32641 agtagcgatt gcggagaaag agaaattgca gaaaaaatat ccaaatgcag aaatcgaaat
    32701 tggtcatttc ggaccagtca ttggtacaca tttaggtgaa aaagccatcg gcattgccat
    32761 ttcagcgcaa taattccttt tattcaaaaa acataccaaa aatattccaa catcatcttg
    32821 gactttctac atgttactaa tgagcgtgta aaagaacgag atggtgtttt tatttctatc
    32881 aatgaagctc tttttctttg caatcctcac ttcaatcctc tataatgtcg catatagttt
    32941 agtaaatgag taaactacta atttacttat ttactaaaaa taaaaggatg aggagttaaa
    33001 ataatggaaa taccaacaaa tttaaaacat aaaccagtaa tcgttgtaga agactatgat
    33061 aaagttgatg gaagaaatgc attaaatacg gatgcaaaag ggctttcact gggccttgct
    33121 cagtggaatg atcgtggaaa agtcgatatc tcaggcaagg tatggcgaca tactggagaa
    33181 aaatggtcac gacagtcgga agaattacca atcacacgta ttttagattt agcgatctta
    33241 gctgcacaag gaagtttata cttccaagat gcttatcgtt atgaaaaatt ttatgatcca
    33301 gaaaatccag tcgtagacat cattggatta caagggaacc gaatgacggt agaagtagat
    33361 accaaaaatc caaagatcga tgaagacatc attttgtatt acgatacact acaaaaagac
    33421 ggagaactga ttggggaacg attccgtatt ttaaaacgtc ttttagatga gctaggatat
    33481 taatagacag agatgatcaa aaggggaaga gaagcatgga gaatttctca ctaacagaaa
    33541 accgaacctt ttcacggcta gaaaagcaaa tgatctggaa gaaaccgaaa agccatcgga
    33601 caagtgcaga agaatggcgg atcgcctccg aaatcaaagg gaattggcaa gatcctgaaa
    33661 tgaaaatcag taacgtactt ttggaaggag atgccgggtc ggggaagaca caattagcca
    33721 aagcactatc tgctgatctg caacttccct atacaaaagt gacctgtttt gcagatatgg
    33781 acaaatcaga tgttttcgga gccttattac ctgtagtaga ttctaataag gaacaagacc
    33841 aagaattact agaagctatt taccaaacag atacacttga agctgtactg acactgatcc
    33901 agaaccatta cggcattgat cctttttctg ctaaagaaaa attagcagag ctagttcaaa
    33961 ggatcgaagc tgattatcca gatgcaatcc attacagcta ttacccttct gaaatcgttc
    34021 gagcgattga aaaaggatat ttattagaga ttcaagagcc gactgtcatc cgagatgcct
    34081 ctgttcttgt ggcacttaac tcagcgctcg aaccaaatgg gatgttgaat ttaccgacag
    34141 gaatcattcg tcgccatcca gattgcgtca ttgtgatcac tacaaatcga aattaccaag
    34201 gaaatcgccc attaaatgaa tctttaagag atcggatgca acatgcggaa aaaatggatc
    34261 ttcctgcctt agaagtcatg gcagaacgtg cgatggcgaa aactatgatc caaaaacaag
    34321 aacttctctt aaagatggca gagattatcc gtttgttgga tgaaactgca aaagctaacg
    34381 ccatcaaagg tgtagcagga atgcgttctt atttttattg ggcaaatacc tataagcaag
    34441 gacaagattt actccagtcg atttatccaa aagttttgta taaattatcc actgattcag
    34501 atgaattggc aattcttgaa caagctttgt ctgacagtgg attgctactg gaacttcagg
    34561 acatattgag aaaagaaaaa tggggtcatc ctcaatctga gcatacaaaa ggaagaacca
    34621 ttagcgccga agaagcaaat gaacgaaaca tcactgaaaa tgctgaagaa attctgcgct
    34681 tagatgaaaa gaaatcgttg tctgctgaag aaccaaatga gggagaagag aaacaagaag
    34741 aaacaataga aaaaaacgag attcctcctc aaatgcaaaa agaacgcagt agcgatatcg
    34801 aaggaaaaaa tcaaaaagaa caacaaacag gagatgattc tcaagaaatg tctgcttctg
    34861 acatggaagc acatgataag gaaatcaaga agcaactgaa taaagaagcg cgacaaatca
    34921 tgaaggaaac gattcatgaa aaagaaggtc tcatcgttca ccgaccagct ttccaaggaa
    34981 aaacgccgga agcacgtgag ctacacatgc aagtaatgcc aatagtagaa tcacttagcc
    35041 ggcaaatttt agagttactg gataatgaac aaacagagac gtaccaaaaa ggaaaatacg
    35101 aaggtcagcg gttcaatgca agcaaagtag catatggtga tttgagaaat tttgacaaaa
    35161 agaacccgcc acatgagcaa ccttctttag cggtagctgt acggatcgat gaatctgggt
    35221 caatgatacg ggatgatcgg atcgaagcgg caaaaaaagc agcgattgcc attgccgaat
    35281 tttctaagaa agtcgatatc ccattgttga tttacggaga tacagcagac cgttcgtcaa
    35341 gagaaaagac ttctttgttt tcttataaag aatttgaaga cggatttcaa tggttaaatg
    35401 aaaaattagt cactatgaaa ccaaggcaaa acaatcgtga tggtgctgca cttcgtttag
    35461 cagcagaaaa attaaacaga caatccgcaa caaccaaact gttgcttaat attagtgacg
    35521 gtcagccaaa agcgttgccg gattatacag gcaaaaaagc aaaagaagat atccagtctg
    35581 ttttgaaaga atatgaacgt caaggaatcc tatttgtctc cgcagctatt ggccaagaca
    35641 aagaagaaat caagtcgatc tacggtgaaa gtcgttttgt agatattact gacttgaatg
    35701 aatttcccaa gcaaatgatt caactgattg cccgctatct atgataaaat aaagctcaac
    35761 gaacgcactt agcagattcg ttgagctttt cgtttctagt taccggtaac aaggatactt
    35821 ctaaaataga atcggttata atcaagaggg accgttaaag gagtgaaacg atatgataca
    35881 agaacaaaaa tggtggaaag aagcagtagg ctatcaaatc tatcctgcta gtttcaaaga
    35941 tagcaatggc gatggtcaag gagacatcaa tgggatccgt gaaaaactta attatttgaa
    36001 agatcttggt atcggcttta tctggatcaa tccgatctat caatctccat ttgtcgataa
    36061 tggttatgac gtaagtgact atcaagatat agaagagaga ttcggaacga tggaagattt
    36121 tgatttattg ctaaaagaag cacatgaatt agggatcaaa gtgattatgg atcttgtcat
    36181 caaccatagt tcggatcagc atcaatggtt tgaagaatcg aaaaaatcta aagaaagccc
    36241 gtatcgcgat tattacattt gggtcgacgg ggtagatggc aaagaaccga ataattggac
    36301 atcgattttc ggcggttctg cttgggagta ttctcatgaa actggacagt attatctgca
    36361 tgtttttgca aaagaacaac cagacttaaa ttgggaaagc gagaaattga aagaagaact
    36421 attcaatatg atccgatggt ggttggataa agggatagat ggatttcgtt tagatgcgat
    36481 ttctcatgta aaaaaagatg aatattcagt aaaagccaca gagaaccctt tctcaccctt
    36541 tcaaaatgtc tcaggaatcg aagaacattt gaccgatttg aaacatgttt ttgaagagta
    36601 cgatatcatg actgtcggag aagcaagtgg tgtcactgca gaagaaggac cacaatgggt
    36661 agggaaagac ggttatttcg atatgatatt cgaatttgat catatccata tctggcagca
    36721 agaaaaagaa gggcaattag atgtccttaa attgaaactt gcattaagcg cttggcaaac
    36781 ttcattggat ggtatcggat ggaacgcttt atatatggaa aaccatgatg ttcctcgtgc
    36841 cgtttcagtg tttggagata ctcgtcccga tttttgggct atgtctgcaa aagcaatcgc
    36901 tatgatgtat ttctttttgc aaggtacgcc atttatttat caaggacagg aaatcggaat
    36961 gacgaatatg ccctttgaat cgatcgatca agttgatgca gtagattcga aaagacttta
    37021 taaaaggctg cttgcggaag gtaagacaag agaagaagca ttggatatca ttcgtgaaac
    37081 aacgagagac aacagcagga cacccatgca atggacttcg gaacaatatg ctggtttttc
    37141 tacacatgaa ccttggctga tcactaatcc aaataccaaa acgatcaatg tagaacaaca
    37201 agaatatgaa ccagagtcgg tcctgcaatt ctataagaac atgatccgca ttagacaaac
    37261 caataaaggt ctgatatacg gttcttataa agaatatctt catgaacatc cacaacttta
    37321 tgtctatgaa agatatttag aagatgaaca atatcttatt atggtaaact taacagaatc
    37381 acttgctgac tatgaacttc caaaagaagc agatcagtcc tggacattac tcttgtcaaa
    37441 ttcctctagc ggagaatttg aagctaaagg catactagca ccttatgaag ctcggttata
    37501 taaaacaaac aagtaaaact tcctcgttaa agttcattag ttggactttg cgaggaagtt
    37561 tttcagattg ctctgtcaat tactcatttc aataattcgc tctaggacca ccgatatatt
    37621 taggacgaga gcgaagggct gtcacgtgag cttgtccaag ggttttcaaa cgaggtctga
    37681 caggtacttg gacatgtttg atatgcatac cgattgatgt gtcaccgata tcgataccgg
    37741 cttgtccaac tacgtgttcc acttcgacag gatcattgaa ctggtcaaaa gcagcaacag
    37801 aacaagcacc tccagcatgt agtgcaggaa caacagagac aatttcgaaa ttttttgctt
    37861 ctgccactgt tcgttctact actaatgctc ggttcaaatg ttcacaacct tggacagcta
    37921 gcgcaatttc tttaggatcc aacaactctt ttaacgtacg gatgatccat tgaccaactt
    37981 ccgcactgga attttttcca atatgtcctc caacgacttc gcttgtgctg catcctaaaa
    38041 caaaaagatc accttttttc aagtgtgcct cagccaatat gtcattaact atttcagtca
    38101 attggtcttt taattctttt tctgacaact tcattttcta aaaccttctt tttcaattaa
    38161 tattgcttcc gtgcttgaat acgttgaaga cttgcagtta taggaaaggc aagtcccatt
    38221 ccaatcagat tttggaagat gtttcctggt atagaagcca ctccagccgg ccaatcatat
    38281 aaaatccaac cggcgatacc atagccgatg atcataacta agcttcctaa taaaagccct
    38341 aatccccaca tacgagtaga agatttgctg aaagaaccag caacatatcc ttgtaacccg
    38401 tggatcacta atgaaaaaac tgcccactgc ggatatcctg aaatcaaatc gatcaataga
    38461 ccactggaag caccaacaac taatccaccc gttggaccat aaagaaaagc agcggtatag
    38521 atcccggcct cgcataatgt cacaaatcca ttcgtagccg gtacagggat caaaattgtt
    38581 aatgaaaggg caactgtcaa cgcaatcagc atagcataga tcgttaattg cttagttttc
    38641 atttctcatt cctccttttt gaataccgcc agaccagaca cttccggtat gatcgttcat
    38701 cagcacgcca ttagaaatac aatgggcaac aaatttttta ctttctgcta ctgctttggt
    38761 aaaatctgcc cctaacacaa gattcgctgt tattgcagaa gaaaaggcac aaccggcccc
    38821 gtttactgtt gtagtgtcga tttttttatg agaaaatacc tcataatgat caattgaata
    38881 gagaagatcc acagcttcat ctccagccat ccttgtgccg cctttgatca caatgttttt
    38941 tgttcctgaa gcagtgagtt ctttagcgag atggatcatt tctgttaacg aagagggaag
    39001 agcttgacca gaaagtaaag cagcttctgc caaattaggc gtaatcatcg taacaagtgg
    39061 aaaaagttct tcgatgagct gcgaaatata caattgattg atcacagctt cagtttcttt
    39121 gaatgccaaa acagggtcta aaatgattgg gatattttgt tttgttttta tgaagtctcg
    39181 aacaaccatg attgcttcac ttgaattcaa taacccaatt ttgataccat ctaatgaagt
    39241 cattttatca atcgaaacta actgtcgttt aagcaattcc aaagatatag attccagcat
    39301 aaatcgctca ttaatatcta gtgcccctat agaagtcaag gcgcttagtc cgaatagacc
    39361 aaaattctca aaagttttta aatctgtttg gattcctcca ccagcaaatg gatcagaacc
    39421 gccaattgtc aagattcttt tcataacatt ttcctccatg aataagagta taacgaaatt
    39481 ttcaaaaaag aaaaacagcc aattggcata tttttatctc atccaattta aaaaaacaaa
    39541 aagaaaagaa agaccaaaat ggatctttct ttccttaaat agttaggact tttgtgattt
    39601 taattctttc tcgatttgaa gccgttgcac tttcattgta gctgttcgcg ggattgcatc
    39661 aaaatcacgg atgataggga cgttcaagcg aggaagttca tggacttgct cccaccatcg
    39721 attccaatcc atttctttat caggagctaa agcaataatc ggttgtggag aatgattttt
    39781 atcccttaca atcactactt ctgccaaaaa atctaacgaa tctaataaaa agtcttcaat
    39841 agctaatgta ctattgatcg tttcgatcaa atccacttgc cgatctttca aaaataggtg
    39901 gccatgctta tccataaaac cgtaatctcc gctatcccac caatcgccat aaacattttc
    39961 ctggaaccgt gcatcttcct tgtaataagt caaagcccgt cctttagaca gtaattgtat
    40021 atgaccatct gtgttttcag gtaggacatt cccaactgaa tctgtaatcc gagcgcttgt
    40081 catgtcttcc agtccaacgc ccatatctct tgcatcactt gttttcaaac tctctagtgt
    40141 atgagcctta agaatcattg gtccgcattc actttggcca tatacttgaa gaaataccgc
    40201 atcctgtgcc atcgacgttc gcaaaaatgt cttcattgtc tggttgttta tagcatcaaa
    40261 agtggagtga tagtatcgga tacccgaaaa agcttctgga tgctccttag cagtaaaacg
    40321 ccactgaaca aagttattcg gatgggtctc tagtgcaatt ggccggtgag cttccaacat
    40381 atgaacaact tttgaacttt gtgcgtttgc taaaggcatc ataggaaatc ccatggacat
    40441 caaagaagag ataccaatat tgaatctgga atgcactgga gagatgtgaa aagcgattaa
    40501 tttcttttcc gaaatttttg tgaaaactgt tttttgccat ttcgtccgcc atcccataga
    40561 atgagcagaa tgacaaataa gtttagggat accagttgta ccagaagtat gggtcatata
    40621 agaaatttca tttttgtcta aaaatgattg agaaacagac aaagcaggtt gttccattaa
    40681 ataaagaata ggaa
//
LOCUS       DAJSMK010000016        37961 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.016, whole genome shotgun sequence.
ACCESSION   DAJSMK010000016 DAJSMK010000000
VERSION     DAJSMK010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.016"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            211..759
                     /gene="aac(6')"
                     /locus_tag="ON488_000859"
     CDS             211..759
                     /gene="aac(6')"
                     /locus_tag="ON488_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCR3231072.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            1305..2966
                     /locus_tag="ON488_000860"
     CDS             1305..2966
                     /locus_tag="ON488_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3231073.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(3036..3383)
                     /locus_tag="ON488_000861"
     CDS             complement(3036..3383)
                     /locus_tag="ON488_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HCR3231074.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            3467..4408
                     /locus_tag="ON488_000862"
     CDS             3467..4408
                     /locus_tag="ON488_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231075.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            4409..5452
                     /locus_tag="ON488_000863"
     CDS             4409..5452
                     /locus_tag="ON488_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231076.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            5458..6528
                     /locus_tag="ON488_000864"
     CDS             5458..6528
                     /locus_tag="ON488_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231077.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            6518..7471
                     /locus_tag="ON488_000865"
     CDS             6518..7471
                     /locus_tag="ON488_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3231078.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            7483..8493
                     /locus_tag="ON488_000866"
     CDS             7483..8493
                     /locus_tag="ON488_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3231079.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(8778..9599)
                     /locus_tag="ON488_000867"
     CDS             complement(8778..9599)
                     /locus_tag="ON488_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCR3231080.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(9696..9974)
                     /locus_tag="ON488_000868"
     CDS             complement(9696..9974)
                     /locus_tag="ON488_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231081.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            10242..12251
                     /gene="metG"
                     /locus_tag="ON488_000869"
     CDS             10242..12251
                     /gene="metG"
                     /locus_tag="ON488_000869"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HCR3231082.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(12730..13317)
                     /locus_tag="ON488_000870"
     CDS             complement(12730..13317)
                     /locus_tag="ON488_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231083.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            13492..14814
                     /locus_tag="ON488_000871"
     CDS             13492..14814
                     /locus_tag="ON488_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3231084.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            14969..15745
                     /locus_tag="ON488_000872"
     CDS             14969..15745
                     /locus_tag="ON488_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCR3231085.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            15738..16307
                     /gene="rnmV"
                     /locus_tag="ON488_000873"
     CDS             15738..16307
                     /gene="rnmV"
                     /locus_tag="ON488_000873"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HCR3231086.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            16300..17184
                     /gene="rsmA"
                     /locus_tag="ON488_000874"
     CDS             16300..17184
                     /gene="rsmA"
                     /locus_tag="ON488_000874"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HCR3231087.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            17635..18264
                     /locus_tag="ON488_000875"
     CDS             17635..18264
                     /locus_tag="ON488_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231088.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(18388..19497)
                     /gene="ugpC"
                     /locus_tag="ON488_000876"
     CDS             complement(18388..19497)
                     /gene="ugpC"
                     /locus_tag="ON488_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HCR3231089.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            19706..20128
                     /gene="mgsA"
                     /locus_tag="ON488_000877"
     CDS             19706..20128
                     /gene="mgsA"
                     /locus_tag="ON488_000877"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HCR3231090.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            20451..20987
                     /locus_tag="ON488_000878"
     CDS             20451..20987
                     /locus_tag="ON488_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCR3231091.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(21027..22790)
                     /locus_tag="ON488_000879"
     CDS             complement(21027..22790)
                     /locus_tag="ON488_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231092.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(22793..24508)
                     /locus_tag="ON488_000880"
     CDS             complement(22793..24508)
                     /locus_tag="ON488_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231093.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(25287..25511)
                     /locus_tag="ON488_000881"
     CDS             complement(25287..25511)
                     /locus_tag="ON488_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231094.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            25702..28479
                     /locus_tag="ON488_000882"
     CDS             25702..28479
                     /locus_tag="ON488_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCR3231095.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            28560..28979
                     /locus_tag="ON488_000883"
     CDS             28560..28979
                     /locus_tag="ON488_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HCR3231096.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            28991..29461
                     /locus_tag="ON488_000884"
     CDS             28991..29461
                     /locus_tag="ON488_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3231097.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            29478..30257
                     /locus_tag="ON488_000885"
     CDS             29478..30257
                     /locus_tag="ON488_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3231098.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            30244..31065
                     /locus_tag="ON488_000886"
     CDS             30244..31065
                     /locus_tag="ON488_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCR3231099.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            31082..32131
                     /locus_tag="ON488_000887"
     CDS             31082..32131
                     /locus_tag="ON488_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR3231100.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            32144..33148
                     /locus_tag="ON488_000888"
     CDS             32144..33148
                     /locus_tag="ON488_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR3231101.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            33781..34800
                     /locus_tag="ON488_000889"
     CDS             33781..34800
                     /locus_tag="ON488_000889"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCR3231102.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            34843..35724
                     /gene="galU"
                     /locus_tag="ON488_000890"
     CDS             34843..35724
                     /gene="galU"
                     /locus_tag="ON488_000890"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCR3231103.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            36024..36401
                     /locus_tag="ON488_000891"
     CDS             36024..36401
                     /locus_tag="ON488_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231104.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            37007..37621
                     /locus_tag="ON488_000892"
     CDS             37007..37621
                     /locus_tag="ON488_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR3231105.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        12438 a         6630 c         7777 g        11116 t
ORIGIN      
        1 gatgaacaaa cagagttttt tcctccaatt gatggctttc ctgatctttc ctattttgaa
       61 taaagtgttt ctgtataatt tttttatttt ataagtaaga taaataatga aagaatagag
      121 atactgattg gtagctaaag atttttgagc gagaacattt cgttttttca aaaggactgt
      181 tagaataagc aagaacaagg gggaagacgt atgataatca gtgaatttga ccgtaataat
      241 ccagtattga aagatcagct ttctgattta ctgagactga cttggccgga agaatatgga
      301 gacagctcgg cagaagaagt agaagaaatg atgaatccag aacgaatcgc ggtagcagcg
      361 gtagaccaag atgagttagt aggatttatt ggtgcaatcc ctcaatacgg tatcacaggt
      421 tgggaattgc atccattagt tgtagaaagc tcccgacgaa agaaccaaat aggtactcga
      481 ttagtcaatt acttagaaaa agaagtagct tccagaggag gaatcacgat ttatttaggt
      541 acggatgatt tagaccatgg aacaacgtta agtcaaacgg acctgtatga gcatacattt
      601 gataaagtgg cttccatcca gaaccttcgt gaacatccgt atgaattcta tgaaaaatta
      661 ggttataaaa tcgtaggtgt cttaccaaat gcaaatggct gggacaaacc ggatatttgg
      721 atggcaaaaa cgattattcc tcgaccaaat tctcaataat aaaaagaggt tgtgacagaa
      781 gtaatcagct tcaagaaata agaaggaatt tacgaaaatt acttcttgaa tttttgtgaa
      841 attccaactt atttccgaag aagctacttt tggaacaccg tgtaccagag gttgtgaaaa
      901 agtcgcttag tttcgagtag taagaaaaat tttgtgaaaa tggctttcta catttttgca
      961 taaatttggc ttaataccga gaaactggct tttgaacacc gtttattcag ataagggact
     1021 gtgacaagac ttttgtcaca gtttcttttt gtttattctt ttttatcttt gtatggcaat
     1081 aatagacaat ataacgaaaa ttatttaatg gcttttggaa gaccatggaa aaccttgtac
     1141 aaagctattt tttctgaaaa attccttgaa acctcacgaa aaaatcatta ttttatgaaa
     1201 aagacaaaaa aaagtgttga ttttttaata attattcatt aaactcttaa acaacttcag
     1261 aaaatattaa ttattctgaa aattccaata aaggggtacg taaaatgaaa aagaaattta
     1321 catttggttt ggttgcggta tgcggccttg tacttgctgg atgttatggc ggcagttcag
     1381 ccacaagcag tagttcagca aaaagcggtt cagcagatgg aggaggcgta tttaacttag
     1441 tcgtgcctca agaaatgcct acagctgact tatcagttgc aacagataca atcagtttta
     1501 cagcattgaa taacgtttat gaaggaattt accgtcttga tgaagacagc aaaccacagc
     1561 cggcaggagc tagcgagttg gcagaagtca gtgaagacgg attaacttac aaaatcaaat
     1621 tacgagaaga cgcaaaatgg tcaaatggtg atcctgttac agcagcggat tacgtttatg
     1681 gctggcaacg aacagtagac ccagctacag cttctgaata tgcttacctg tatgcgccag
     1741 ttgaaaatgc agaagacatt acagctggaa agaaagataa atcagaacta gggatcaaag
     1801 cagttggtga ctatgaatta gaaatcaaat tgacgaaaca aacaccatat ttccaatatc
     1861 tgcttgcttt cccatcattt ttcccacaaa aacaatccgt agtggaagaa aatggggatg
     1921 cctatgcatc tgcaagtgat aaagctgttt ataatggacc attcacatta gaagattttg
     1981 atggaccagg aacagataca gaatggactt ataagaaaaa tgatcattac tgggacaaag
     2041 atacagtaaa actttctgaa atcaaagtca gtgtagtaaa agaatcttct actgcattga
     2101 acttattcaa agatggccaa gcagatgacg tgatcttgtc tggtgagtta gcacagcaaa
     2161 acgcaaacga tccagcttat acttctgtta aagaagcgcg gacaagctat atcgaattca
     2221 atcaacgtga aaagaattca ccattcaaca atgtgaacct aagaaaagct atttcttatt
     2281 ctatcgatcg tgaagcttta gtaaaacaag tactaggtga cggatcagtt gtctctacag
     2341 gattgatccc atcagatatg gtaaaaagtc caacaacgaa cgaagacttt gcaaaagaag
     2401 ctggaaaatt agtttcttat gacaaagata aagcaaaaga atattgggaa aaagcgaaaa
     2461 aagaattggg cgttgattct ttagaatttg atttgatggc ttctgatgat gattcatcga
     2521 aaaaagtaat cgaatatgtt caaaactcaa tccaagaaaa cttggatggc gtaacagtca
     2581 aaccaacacc tgttccattc tctgtacgtc ttgaccgctc aacttcgggt gattttgacg
     2641 cagtactagg cggatgggct gctgactatg cagacccaag cagctttact gatttgtttg
     2701 tcacaggtaa ttcatacaac cgtggtcgct ggagcaatgc agaatatgac gaagcagtta
     2761 aagcagcttc atcaacagac gctggcgatg aacaagcccg ttgggatgat ttccaaaaag
     2821 caatcaagat catctctgat gatatgggtg tcgttccggt gtaccaaaaa gcagaaggtc
     2881 acctagtgaa tgaaaaaatc aaaggtatcg ttcaccatgc ggcaggcgct tcatgggatt
     2941 acaaatggac atacgttgaa gaataatcgt taataccgtg agcatgagaa aaaacgaggc
     3001 tgcggcaaat gtcgcaacct cgttctcata ttcacttatc ctaacaaaga aaaaagcatg
     3061 aaaatagcag aaagagcaat tagtattccg gcaatgatca gccaaaagct gtacataccg
     3121 tagctggcag acgagagcga ggaaaattct ggttttttct ttcggttcct tgttcgtgca
     3181 agatggaccg atcgctgaaa atgatcgaag aaacccgaag aaaagaccca taaaaaaccg
     3241 ccgataatca gaaacggcaa tgaccataag aatagatcat tagataattg aatgagtgta
     3301 aaggaatggt tgatgagatt ttttattaaa ataaccagaa tcagtagaaa agctactgcg
     3361 taggggatag attttttttt catttgattg ctcctttatt tttggttcat tatctaataa
     3421 tgtagcgaaa catctgtcag aagtcaaaag ctagggggaa acattagtga atagttatat
     3481 caaatatgta ttaaaacgtg tctttttcat gatcatcacg ctttggttaa ttgcaacaat
     3541 cacctttttc ttgatgcaat tgctgccggg cacgccatat acgaatcagg aacgtttgag
     3601 tcctgaaaca atcgagatgc taaataaaca agtcggtttg gataaaccag ttatcgtaca
     3661 atatgggatt tatctttcta atttgcttca aggagatttt ggaatttcct tccaatttaa
     3721 aaaccagcca gtcgcacatt tgttagctgg aagaatcgga ccatccttgc agttagggtt
     3781 acaggcaatt atctttggaa cagtcctagg gacgatttta ggaacgatct ctgccatgaa
     3841 gcaaaataca tgggcagata catcttctac actcgtagcg atattaggtc gttccattcc
     3901 aaactttgta tttgctgttt tattacaata tatctttgca atcaaattac aagttttgcc
     3961 aatcgcaaaa tgggatggct ttgtgtacac aatcttacca acaattgcgt tggccatgtc
     4021 gccgcttgct gactctgctc ggtttatccg tacggaaatg gtggaagtac tgcatagtga
     4081 ttatgtggaa ttagcaaaag caaaaggatt gagccgttgg gaaatcgcct ttaaacatgg
     4141 tcttcgaaat agtttgattc cattgatgac tttattagga ccgttagctg tagcattgat
     4201 gaccggatca ctggtggtag aaaatatctt tgctattcct ggtatcgggg aacaattcgt
     4261 taagtcaatc acaacaaatg attatcctac gatcatggct gtaacgatcc tttactcatt
     4321 tatgctgatt tttgttattt tgatcgtgga tctattgtac ggtctagttg atccaagaat
     4381 tcgtgtttca gaagggagcc gaggataaat ggaaatgata ccaaagcgtt atgaaacagt
     4441 tgcagatatc cctgcggatg aatttcttcc attacaaaaa aataccgaag aagaacgtga
     4501 acagattact gcaccttctt tgaattttat ccaagattca tggcgccgtt taaagaaaaa
     4561 caaagctgcc gttatttcaa tggttttact attggtcatc attttgatct ctgtgatcac
     4621 aatctttgtt tctcctcatg atccaactgc ccaaaacgtg gcttatatca atttgcctcc
     4681 tcgtattccg ggaatcaata tcgatggatt gaatggaaaa gcaatggttg gtggtgaact
     4741 tgttgataaa tatgctcaag caaacgtccc ttcaaacgta aatttctttt taggaacaga
     4801 cggtttggga cgtgatgtat taagccgctt atttatggga atgagaatct cgttgctgat
     4861 cgcatttatt gctgcattac tagatgtaac gattggtgta gcttacgggt tggtttctgg
     4921 tttgttaggc ggacgtgtcg ataacgtgat gcaacgtttt ttggaaatct tatcaggaat
     4981 tccaaacctc gttgtcatga ttttgatgtt ggtcgttttt gaaccaggaa ttttttcaat
     5041 cgtggctgct atggccatca caaactggat accaatggca cgtatcgttc gtgcacaaac
     5101 aatgaaatta aaagatcaag aatatgtttt agctggattg acattaggtg aatcaagaat
     5161 gaaaattgca ttcaaacata ttttgccgaa tatctctagt gtcattatta ttcaaatgat
     5221 gtttagtatt ccatctgcta ttttcttcga agccttttta agctttatcg gtttaggtct
     5281 tacgcctccg tcagcttcat taggaacgat gttgagcgaa gggtacaaga cattcctgta
     5341 tctgccttat ctattatgga ttccggcagt aactttatcg gttatcatga ttggctttaa
     5401 cttacttgct gatggattgc gtgatgcctt tgatcctaaa atgaaagagt gaagacgatg
     5461 acgaaaattt tagaagtgaa agacttagaa atctcttttg atacgtatgc tggaaaggta
     5521 cgagcgattc gcggtgtcaa ttttcatttg aataaaggag aaacattggc gatcgttggg
     5581 gaatctggaa gtggaaaatc agtgacgacc agaagcatca tgcgcttgct gtcaagcaac
     5641 gccaatatag atgctggtca aatcctcttt aaaggtaacg atatcgttgg aaaatcagaa
     5701 agagagatgc aaaaaatccg tggtaaagaa atagcgatga ttttccaaga tccaatgacc
     5761 tctttagatc cgacgatgcc cattgggaag caagtcgctg agtcccttag aaagcataat
     5821 aaagtttcaa aaaaagaggg acaaaaagct gcattagaat tgcttaaatt agttggaata
     5881 cccgaagctg agaaacgtat caacagttat ccgcatcagt tctcaggagg tcagcgtcaa
     5941 cggatcgtga tcgcgattgc actggtatgt tatccggaaa tcctgattgc tgatgaacct
     6001 acaacagcgc ttgatgtgac tattcaagca cagattttgg agctgctgaa agaaattcag
     6061 acaaaaatcg atacatcaat tatctttatc actcatgacc ttggtgtagt agcgaatgtc
     6121 gctgatcgtg tcgctgtcat gtatggagga agaatcgttg aagttggaac atcggaagaa
     6181 attttctaca acccgcaaca tccctatact tggggactgc ttggttcaat gccgacatta
     6241 gatagtgcga acgatcgatt gtatgctatt cctggttctc caccggattt attgaacccg
     6301 ccaaaaggag acgcattcta tccaagaaat gaattcgcga tgaaaatcga tgcagaacaa
     6361 gaaccaccat tttttgaact atcaaaaaca cacaaggcag caacttggct acttgctccg
     6421 caggcaccca aagtgacacc gccagaagaa atccaacgtc gctgggctat ctttaaagag
     6481 aaacaaaaac atacttacgg tcaaggagga attgctgatg ccaaataaac tacttgaagt
     6541 taaaggattg aaacagtatt tcaatgtagg aaaaaagaat gaagtacatg ctgtaaatga
     6601 catcagcttt cacatttatg aaggagaaac attcggttta gttggagaat ctggaagcgg
     6661 aaaatccact actggccgta cgatcattcg cttgaatgaa cctactgatg gtgagatatt
     6721 attcgacggt caagatataa cgaagatcaa agataaaaaa ggtttgacga aattccggca
     6781 tgatgttcag atgatctttc aagatccata cgcttcgttg aatcctcgta tgaaagtcag
     6841 agatatcatt gccgaaggaa ttgatgttaa tggactagct aaatcatctg aagagcgtgc
     6901 aaaaaaagtc gatgatctat tgagaactgt tggattgaat ccaagccacg gtactcgtta
     6961 tcctcatgaa ttttcaggtg ggcaacgcca gcgtattggt attgcacgag cattggcagt
     7021 aaaaccgcgt tttatcattt gtgatgaacc aatttctgca ctagatgtgt cgatccaagc
     7081 ccaagtggtc aatttgttgc aagatctcca aaaagaacat caattgacct atctatttat
     7141 tgcacatgat ttgtcgatgg ttaaacatat tagtgaccga atcggtgtaa tgcataacgg
     7201 cttgttatta gagatgggaa caagtgatga aatctataat cacggtgttc atccttatac
     7261 agaaagtttg ttatctgcta ttcctctacc agatccagac catgagagaa aacgcagaag
     7321 aatcaaatat caacctgaac cagatgacgg acaagtacgt caacttcgtg aaatcgcacc
     7381 agaacatttt gtctatgcaa ctgagcagga agtcccatat tacgcaaaaa aactaaaacg
     7441 acaaaaggaa tctcttctgg ttgctaacta ggagggacat agatgctaaa agcttttaaa
     7501 ttccgtatgt atccgacaga agaacaaaaa cagcaattga ttcgtacttt tggatgtgct
     7561 cgatttacct ataaccattt gctgaaaaag cggcagaaaa gttggcaaca aacaggagta
     7621 gccaattttt cgctcacacc cgctacatta aaaaaagaat acccattctt aaaagaagta
     7681 gacagtcttg ctttagcaaa tgcacagctt aatttggatc gggcttttcg caattatttc
     7741 aagggacgtg ccagcttccc aaagcttaaa acgaaaaaaa gtatgtggca atcttatacg
     7801 accaacaacc aaacccgtac gatctatctg gaaaatggct acttaaagtt accaaaacaa
     7861 aaagaactaa tcaagataaa tcagcatcgg ccagttgaag gatcgattcg ctccgctacg
     7921 atttctgctc gatataatga agaattttat gtcgcactac tttgtgatgt ttcgccagta
     7981 aaaaaagaat ctttagctaa atggatcggg atcgcctatc atccgaagac attgatccaa
     8041 acatctcgac ctctagaagt aactttacca aaatttcacc agacagaaga aaagctgcaa
     8101 catgcacagc ggaaattgaa tgtgaaagtc cgctccgctc accatagaaa gatcaggtta
     8161 gatcaggcaa gcaattatca gaaacaaaag agaaaagtaa tggatcttta tctgaaacaa
     8221 aagaaccagc gagaagatta tcttgaacaa ttatctggga aattggtcaa acaatatgac
     8281 tacttatttg tagaatcttt tccaaaagaa gaggcacatg ctgatttttc tattcacgac
     8341 tggcataaat taataacaaa attgcgttat aagtcccaat ggtataataa aaaatttctt
     8401 ttgatcaata ccgacggagc agaagaaagc aattccgtaa gaaagagcca agtagtagaa
     8461 aaaatgggca gacattcggt tatcaaggga taaaaaatga atgaaactga taggagcgtt
     8521 agggttagcc ttgttaataa aaagtcttaa tgacttttgt ttctaggaat ttttcttttg
     8581 aagaaaagct cactaattat gacaaaccaa taaaacaata gcagaaaaag ttcgtacgag
     8641 ctttttctgc tattgttaat tttttattca gaaagtttac gaatacatca aaattctgaa
     8701 acaaaaaacg taactcacaa agagttgttt ttgcgttttt tcttgaatga ttaggtctga
     8761 atcttttgct cacaacctta ttcatggtgc cccggcttga gctgatagat ttttgaagga
     8821 cggccgattc ctacaggacg ttcaccgatc tcatcgaaat attggagcat agctttctta
     8881 aaattggaat gatcgatcgt tttataatcg atccctaaga atttagcaaa tacttttcga
     8941 gcttccgtaa tcgtgaaatc tttacctaaa acttgtagaa cttgcggctc gtgttccatt
     9001 ttattgacta cacggttgaa tgctttcaag atgatttgac tatggtcaaa agccaaagta
     9061 tctttgccag aagactctcc agtgactaaa tcaagcgaga tagccacttc tccgctagat
     9121 aaatggatct tgttactatg acgttctagt gtgaaccagc gtacttcctt ggcatcatct
     9181 ccggcgatta gcggttcttc tccaataaag gctaagtagc tgactgtgac gacccagcct
     9241 cgcggatctc gattaggcgt actgaatgta tgcagttgct caatattttc ttttgaaata
     9301 accacaccag tttcttcctt tgtttctctt aagacgcttt ctccagttga ctcatccttt
     9361 tggacaaagc caccaggcaa tgcccatgaa tttcgataag gatgcccttt tctttggatc
     9421 aacaaaactt tcagctgatc ttcttctttg ttatagcaca tcagtacgat atcgacagtc
     9481 aaagagggct tgtcatattc tggacgttcc tgtttttgat accagttaag aaattcttct
     9541 tcacttgctt tatgttcata atataatttt tcttcttctt tagaagcaaa acggttcatc
     9601 tgaccacctc cattgacagt aaaagtactt tttaccttat tgtagcagac tctgaaaaaa
     9661 aaccaaggat ttacttgaaa aatctaggtt atcatttaaa tatgaaaaat aaatggaagt
     9721 atgagattga ataaaaagaa aagcagataa aacggcaata ctttataccg ctcttcacga
     9781 atggcaaaga agccacaaat aacgatatat acgtcaatga taaaacgcaa aatccaagct
     9841 gctgtcataa aactgttcaa atgcccatgg aggttaaaat aaccatacat acgaatataa
     9901 aaatagctga atattaaatg tgctaatgaa agaaaagcaa tactaagtgt aaaaaaaaga
     9961 tgtttcttct gcatgattgt tccagtccct tactaagata gatagtcttt attataccac
    10021 gtgtgagggg agaaataaaa agccgttttt tagtagatat gaaacaaaac aaaaacccgc
    10081 atttattcaa cctattcatc cttttaaagg atagattgaa cgtagataga agtcgtttat
    10141 ccagtctttt tcattttgaa aaaaagctaa cagcatgctt tttttatggt atactagcaa
    10201 ggaaacgaat tcgcatcatg cgataaagga ggaagagccc cgtggcagaa aaggaaactt
    10261 tttatatcac tacgccaatc tattatccaa gcggcaaact tcatatcggc aactcgtata
    10321 ctacgattgc atgtgacgca attgctcgtt ataaacggtt gatgggcttt gatgtgtttt
    10381 atctcactgg agtggatgaa catggtcaaa aaatcgaaac aaaagcagaa gaactaggtg
    10441 taaaaccgca agaatatgta gataaaatgg cggctgatgt caagaaatta tggaaaacgc
    10501 ttgatatcag ttatgataaa ttcattcgca cgacagatga ttaccataaa gcagctgttc
    10561 aaaaaatatt tgatcgttta ttagaacagg gagatattta cttaggtgaa tatgaaggct
    10621 ggtactctgt ttctgacgaa gaattcttta cagaaacaca acttgcagaa gtgtacaaag
    10681 atgacgaagg taacgtgatc ggtggtaaag cgccaagtgg acacgaagta gaattggtaa
    10741 aagaagaatc atacttcttc cgcatgagca aatacgcaga ccgtctattg gaatactatg
    10801 aagaacatcc cgaattcatc cagccagaat ctcgtaaaaa cgaaatgatc aacaacttta
    10861 tcaaaccagg attagaggat cttgcagttt cacgaacaac ttttacttgg ggagtaccag
    10921 tcaagagtga tccgaaacat gtggtgtatg tatggatcga tgcattatcc aattatatta
    10981 ctgcactagg atatggctcc gaagatgaaa gtctattcga aaaatactgg cctgcagatg
    11041 ttcagatggt cggtaaagaa atcgttcgct ttcatacgat ctattggcca atcatgctga
    11101 tggcccttga tttgcctcta cctaaaaaag tatttgggca tggctggcta ttgatgaaag
    11161 acggaaaaat gtctaaatca aaaggaaatg tcgtttatcc tgaaatgctt gtggaacgtt
    11221 atggtttaga tgcactccgt tattatttgc ttcgtgctgt tccgtttggg tcagatggtg
    11281 tctttacgcc agaagatttt gtttcccgtg tcaattatga tctggcaaat gatctaggga
    11341 acttattgaa tcgaacgatt gctatgatca acaaatattg tgatggactc gttcctgact
    11401 atgcctcact tgtcactcca tttgatagtg aactgtctac gacggctgct aacgttgtcg
    11461 gacgttacca tgatgcaatg gaaaaaatgg aattcaatac agcattggct gaaatctggg
    11521 tgctgatttc tcgtgcaaac aaatacattg atgaaacaga accatgggta ttagcaaaag
    11581 acgaagaaaa gaaagctgaa ttgaatagtg tcatgatcca tttagctgaa tctttgcgta
    11641 tcgcagcgat attacttcag ccaatcatga cagaaacgcc agagaagatc ttcaatcaac
    11701 taggattgga ctctgaaaca atgaatcttg aaggattaca ctttggcgaa tttccttcag
    11761 gaacaaaagt agttgcaaaa ggtacaccaa tcttcccacg tttagatatg gaagaagaag
    11821 ttgcttttat tcaagaaaaa atgtctgaag gtactcaaac aaacgaagat acagtcaaat
    11881 gggatccaga agaaacagaa cttgtttcaa cgaaagaaaa acaaatcaaa tttgatgtat
    11941 ttgaaaaagt agaactaaaa gtagcagaag tcatcaactg tcaaaaagta gaaggggcag
    12001 ataagttgct gcaattccga ctagatgctg gagacagcca agaccgtcaa atcttgtcag
    12061 gaatcgctga attttatcct gatccaagcg aattgatcgg gaaaaaagtc gtcattgtag
    12121 caaatctgaa accacgaaag atgcgtggac aaatcagtca aggaatgatc ctttctgcag
    12181 aagcaccaga tggctcttta caagtaatcg aagcaccaaa atccatgcca aatggctcag
    12241 aaatcgcata gaaattcaaa gggggtatga cactagttgt gtcatacccc ctttttccga
    12301 aatttgagaa gcaattttcg taaattcctt cttattactt gaagccaatc atataataca
    12361 gaaacagaga actatccaaa ataaatccta gaaaaagaag tacgagcttc gctgattttt
    12421 gttaatttag aataatacta ataggaatcg taaaaacaga aaaaaagcat aatgataaag
    12481 ggtcgggcag attttaattg attcatctgg tactcttttt tattgtcctt acattcataa
    12541 agtttgaatg caatgacttt attacatcta tatttatatc taacagtagc gttgatgtgt
    12601 taattataag ttctatcact ttatgttcaa ttagtttgtg ctcttatatg tgtgattgaa
    12661 aatatagata aaaaaacaat catcggcttt gacttcgatg attgttttct ttattttgta
    12721 aaaatcctat cacttgattt tatggtaacc ttttattttt gtcttcaaac ggcttggtaa
    12781 gagagcagta agcagtgcaa atgggatcga aaagacatac cagaaaatcg tacgtccgat
    12841 accataatgt tgatagagct ttgtcaacat cacgtgtaac aagatcaacc ctaaaagcaa
    12901 ggagccagct ataaaccaat gattatccca atgcatgact tcactaagtg ccatcactcc
    12961 aaaaggatag aaataaaaat agatcccgac taaggtcatc cgccagttct ttgtaaatgt
    13021 tccgatattc aataaaaaga aaatcgctga aagcaaaata ccgataggcg gaaaaagccc
    13081 aaccaaaaag gaatacaaca tcccccacaa gatcatcaca ggacctttga tcaatgcaac
    13141 gattgcgatg aacaaagtca gcaatattag tttttgtgat aacgttgcaa cagtcattaa
    13201 tccaaataaa attaatgtga accaatgcca atgggactgc tgttgttctt tacgggaaaa
    13261 atcgacccgg ttggataaat aatctgctaa tttcggataa gaacgcttaa aatccataaa
    13321 ctgttcctcc ttcgtggaaa aggtaggttt agtatacgaa aaataaaaaa gaaatacatc
    13381 cgtcttaaga gggagttttt cactgaaagt ggagaaaaaa gaatggtaaa ttaaaatatt
    13441 ctcagttata ctgaaaatta taccaaattt caaagaagaa agaggatggg aatgaaaggc
    13501 aaactaaaac gagaaatcaa tctgtttggc gcattagcta ccgttatggg aaccgtgatc
    13561 ggtgcaggcg tcttcttcaa aactgctgct gttactgcta gtactcagtc tacaagtttg
    13621 acattgctag cttggctttt gggtggtttc ttaacgatct gtgctggatt gacagtggct
    13681 gaattagcta cagcaatccc ggaaactggt ggagctgtaa aatatattga agctgcgtat
    13741 ggaaaattgc ccagcttttt attaggatgg gcgcaaagct tgatttactt tcctgctaat
    13801 attgctgcat tatcgattat ctttgcgaca caattgacga acttattaca attatctacc
    13861 gattatcttt tgttgattgc agtgatcacc gctgtttctg tgacagggtt gaatttgtta
    13921 gggacaaaag tcggtgcttc tgtacaatca gtgacgttga ttgttaaatt aataccaatt
    13981 gctgtgattg tcatatgggg attattgacc ccaggacaag gaactgtcca gttatttcca
    14041 atcgaagctg gaaaagatgt tacttttgtc gaaggattga gcagtgcgtt gttagcaacg
    14101 ttgtttgctt atgacggctg gttaggtgtc ggtgcaatgg caggggaaat gaaacggccg
    14161 gaaaaagatt tgcctaaagc aattattctt ggtttgagtt ttgtaacagt cgtttatcta
    14221 ttgatcaatt ttgttttttt gaaaactttg ccgattgatc atcttgccgg taatttgaat
    14281 gcagcttctg aagcatcaga cgtcattttt ggaggaatcg gtggaaagct ggtcactatt
    14341 gggatcttga tctcggtata cggtgcattg aacggttata cactaactgg gatccgcgtg
    14401 ccttatgcga tggctttaga agacgagcta cctttcagta aacagctgac aaagctttca
    14461 aagaagttta cggttcctta tgttcctgcg gttttccagt tagcagtagc ttgtattatg
    14521 atgagccttg gttctttcga ctttttaaca gacatgttga tttttgtgat gtggctattc
    14581 agtttactga tttttatcgg tgtctttatt ttaagaaaaa aagcgccgga attgccacgt
    14641 ccatataaag taccacttta tccaatcgtt ccgattattg cgattctcgg tgctattttc
    14701 attttaggta tgacgatgat gacgcaaacg aaattagcat tgatcggtat aggtgttacc
    14761 ttgataggta tcccagtcta ttatcaaaaa aagaaaaaac gctcagaaga gtaaaatatt
    14821 tcaacaacag acagaaaaag tacgaactag gtcctctaga tcttcgtgct ttttctattt
    14881 caataaaaca agttcttcta ttttgatttt tgctacttct gcaagtagtg cttatgtgct
    14941 aaagtaagaa tgaaaaggag agataaacat gatatttgat tctcataccc atttaaatgc
    15001 tgaacagttc aatgaagata ttccagaaac gattcagcga gcacaagaaa tgggggtaac
    15061 gaaaatggcg gtcgtgggct tcgatacgcc aacgattgaa aagtctttgc aattaagcca
    15121 tgactatcca aatatataca gtattatcgg ctggcatccg acagaggctg gcagttatac
    15181 gaaagaaatc gaaaataaat tacaagaaca attgacttta ccaaaggttg tagcattagg
    15241 ggaaattggc ttggattatc attggatgga agacccgaaa gaagtccaag ataaagtatt
    15301 tcgcagacag attgctatcg caaaagaaat gaacctacca atcagtattc atactagaga
    15361 agcacttgaa gacacgtatc aaatcctaaa agaagaagat gttcgagata tcggtggaat
    15421 catgcatagt ttcagtggtg attatgaatg ggcaaaacga tttcttgact tagggatgca
    15481 tatttcattt agcggtgtcg tcactttcaa aaaagcatta gacgtccaag aggctgcagc
    15541 aaatgtacca atcgaacgat tacttgtgga aacagatgcc ccttatctgg caccagttcc
    15601 ttttagagga aagcgaaatg aaccaggcta tactcgttat acagtagaaa agattgctga
    15661 acttcggaat cttccgacag aagaagtggc tgcccaaaca tggacaaatg cgcaccgatt
    15721 atttggtcta agcgaacatg gataagatga agatccaaga gattatagtc gttgaaggaa
    15781 aagacgatac aagaaggctg cgggaagtag ttgatgcaga tacgatagaa acaatagggt
    15841 ctgcaatcaa tgaagagatc ctgatgcaaa ttgaacatgc ccaagagact cgtggagtga
    15901 tcgtttttac cgatcctgat ttttcaggag aaaaaataag aaaaatcatt atggaagctg
    15961 ttcctcaggc aaaacatgct tttttgccgc gcacacaagc taaaccaaag aaaaagggaa
    16021 gccttggtgt cgagcatgca agtgatgctg ctattttaga agcattgaaa aaggtcgtga
    16081 cgccagacat ttcccaaacg gctgtttctg aaatcactag acaagacctt ttagactatg
    16141 gtttaatagc tggggcacaa gcaaaagaaa aacgagaaaa actaggtgac gagttgcgca
    16201 tcggttacac gaacggcaaa caattggaaa aacgtttgaa gatgtttcgt attacgccga
    16261 aagaactcgc ccaagcaatg aaaatagtgg aggaacaaca tgagtgaata tcgtgaaatt
    16321 gcgacaccct ctagaacaaa agagatttta ttgaaacatg gtttttcatt taaaaaaagt
    16381 ttaggacaaa attttctgac tgaaccaaat attttaagga aaatcgtaga aactgcgcaa
    16441 atagatgaac atacgaacgt gatcgaagtt ggaccaggaa tcggtgcatt gacggaacaa
    16501 ttagccaagc atgcaaaaca agtcgtagca tttgagatcg atgatcgttt gatccctgta
    16561 ttggctgata cgatgcaacc ctatgacaat gtgactattg tacatcaaga tattttaaag
    16621 accgatttgt caacagctgt tagagaaaca tttcatgagg agcttccgtt aaaagtcgta
    16681 gcgaatttac cttactatat tacgacaccg atcatgatgc attttcttga atcagatttg
    16741 gttgtggatg aactagtcgt catgatgcaa aaagaagtag ctgatcgtat ctctgctgaa
    16801 ccaggaacga aagcttatgg ttcattatcg attgctgttc aatattatat ggaagccagt
    16861 ttagcattca tcgtaccaaa aacagtattt gtccctcagc caaatgtaga ttcagcgatt
    16921 ttgaaactga caagaagaga tataccggca gtcgaagtga cagacgaaaa agcatttttc
    16981 cgattgacaa aagcggcatt tcagcaaaga agaaaaacgc tttggaataa cttgcagcat
    17041 tcgtatggca aagatgacca gacaaaagca tggttagcaa aaagcttgga aacagctgga
    17101 atcgatccaa aacgtcgtgg ggagactttg tcattacaag aattcgccgc attaagcaat
    17161 gcgatgtcag aaaatatgca gtaaaaaaag aggttgtgac agaagttgtg aaaaagctgt
    17221 cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatgtttt tcgtttgttt
    17281 gggcttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt tgtgggcctg
    17341 ccgtttaact ctaagtcaca aggaacaatt tcaaaaaaca gcttctcatg tttttgagtt
    17401 agttggtctt attacttgat gcaagctttt gaccactatt atgccgaaca aggagatgtg
    17461 acacaaattt tgtcacatct cctatttttg tttcttgatc aaaaaattct tatacttgat
    17521 actcacactc attttgtatg gatttagaaa agaatatgtg tcttgacagt tattagtaag
    17581 tgagttatac taagtcgaca tttatgtgtc aagacatatt aggagagaga aaaaatgaga
    17641 aaaaattcag ttcgaaaact aacgatttct gctttattga ttgggatggg ggtcattatc
    17701 ccaatggtca tgcctaaaat catgattcca ccagcttcct ttactttggc gtctcatgtg
    17761 ccattattta ttgcgatgtt ttttacacca ggagttgcag tggctgttgc gctaggtacg
    17821 acatttggtt tctttttaac aacgccggtt atcatcgcat tgcgagcatt gtcacatctt
    17881 gtgtttgcgt tgattggggc ttggtacttg caaaagcatc cgagtatcgt tttaaaaaat
    17941 ggacagttta cttttgctaa ttggcgtttc caagggttca attttgtgat cggtgtgatt
    18001 cattctttag cagaaatgct agtagtcagc atcttttact ttattggtaa tatgcctgaa
    18061 acatattatt ctcaaggata tttttataca gtattcatct tgatggggat tggtgggctt
    18121 atccacagtt tagttgatta taatattgct tattttatag caggaacact cagcaaatat
    18181 tttgatatcc ccgtatttac ggcagcaaaa aaagaaaatc ggaaagagtc gattcaaggg
    18241 tacgcgaaga aaacgacata ttagacatga tctctcaaaa aaaaaactct catctagtaa
    18301 tggataataa atcctctaag atgagagttt tttgtcctaa aaagagctgc accaacatct
    18361 tctggcacag ctctaacagg gggcaattta tggaagtttg atgacttgtt ctgtttcttt
    18421 atcaaagaag tggcctttgc tgatgttgaa ggcaaggtcg actatttcgc ctggtttatg
    18481 gaaatctctt gcatctactt ttgagatgaa ctcagtagaa ccagtttttg tgtaaagcat
    18541 cgtttcagct ccaagtaatt cggaaacgac aacttctgat ttcactacgg cttcaggtga
    18601 agcttcaagg gctacttgtt cactgtggat gtcttctgga cgaataccga agataacttc
    18661 ttttccttca taaccttttt caactaatac tttgtttttt ccttcaggaa tacgaagctt
    18721 aagcccatgt ccatctgtga taacaccatt tttcaatgtc acattaaaga agttcatggc
    18781 aggagatcca ataaagccgg caacgaacat attgacgggt gtatcataaa cttctttcgg
    18841 tgtaccgatt tgttggataa atccgtcttt catgataacg attcggtcag ccatagtcat
    18901 tgcttctgtc tgatcgtgag taacatagat ggtcgttgtt tcaagacgct ggtgaagttt
    18961 ggcaatctca gcacgcatgg ctacacgtaa tttagcatct aaatttgata atggctcatc
    19021 cattaagaag acttttgcat cccgaacgat tgcccgtccc aatgccacac gttggcgttg
    19081 tccaccagat aaagcagctg gttttcgttt caagtattct gtcagaccta agatctctgc
    19141 tgcattgtcc acacgttttt tgatgtctgc tttatcatat ttacgtaatt tcaagccaaa
    19201 agccatatta tcaaaaacag tcatatgagg atacaatgcg tagttttgga aaaccatggc
    19261 aatatcacgg tctttaggtg ccacgtcatt catgactttt ccgccgatat ttagttctcc
    19321 ttcagagata tcttccagtc ccgcgatcat tcgcaaagta gttgactttc cacaaccgga
    19381 aggaccaaca aaaacgataa attcacggtc tttgattgat agattaaaat cagttacaga
    19441 ataattttct gcattgtcat attttttata tacgtttttc agagccattt ctaccataat
    19501 acgttccaca ctttcttttt tagttttatt aactatttaa agtataaatg aaagcgttaa
    19561 ctaacttcaa tgtcatgttg aacaagaatt ttttcttttt tttgtcaatg tgctagtttt
    19621 aagctttaat aaatatccat aagaaataaa aactgataca ctggagtaaa taagtatgtt
    19681 aacaatatca aaaggagtgt ctcttatgaa aatcgctttg atcgctcatg accgaaaaaa
    19741 acctatgatg gtgaaattag caacagcgta taaaacaata ttggaaaaac atgaactttt
    19801 tgctaccggg acgactgggc agaggatcac ggaagcaacc ggcttgccga tccatcggtt
    19861 taaatccgga ccgttaggcg gggatcagca aattggagcc atgatttcgg aggatcagtt
    19921 agatttggtg atttttcttc gagacccgct ggctgcacag ccccatgaac cagatgtaac
    19981 agcacttatc cgtttatctg atgtctatga gattccgtta gctacgaata tcggaacagc
    20041 tgaggtgcta ctaagaggac tggaagccgg cttcctagat tttcgaagaa tcgtccatga
    20101 aatagacaag catccacttt cattttgatg gataagcgtg tggaaaaata acgtttaatg
    20161 ttcgcctata tgtagctata aaagctaaac aaactgataa tatgcgatat aatacgaacg
    20221 tattggataa tataaacaat aatattagtt tttcgtattt gcagtaaatg tgaaaatatg
    20281 ctatagtttc tgtgggaaaa gatcccaaaa ataatacaga gtagaaaata aagcgttaag
    20341 tgctaagagg atgggatgtt gcctcttgga cgaaggacgt aatgttcgcg gttttatttt
    20401 cgcattcgct gcatgatacg atgtagcagc tcttaaagga gatgctaaaa atgaagaaac
    20461 accggttaga cgcacgtatg attgctatta tgggcttatt gattgcattg atggtcactt
    20521 tgtcccgact ggtagcaatc gagaccccat ttattaaaat cagtgtcaca tttattccac
    20581 aagtgatcat gggcattctt tttggtcctt tttggtcagg gataggcgca gttttagctg
    20641 atttagtagg aatggccctc ttctcgaaat ctgcattctt tattggattt acattgaatg
    20701 catttattga aggagcaatc tacggattct ttttctatcg aaaagagatc acttggaaaa
    20761 atgccattct ggctacgctt agtgtcacgc tgatcatcaa cttatttttg acaccattat
    20821 ggcttgcgtt gatgtaccat gtgccattgt tcagctgggt cgtttgggcg ccccgcctgt
    20881 taaaaacagt aatatggtta ccgattcaat caattgccat ttattacgta ggacgtagta
    20941 ttccttacaa aaaaatttta agaagtttag cgatccacgc taaataaaaa acaagcagtc
    21001 ttcccatccc agaagactgc ttgtttttat tgtgctgtga attgtgcttg atagagccgt
    21061 cggtaataac catctttttg aagcagctca tcatgggtgc ccatttcgac aatagctccc
    21121 tgatccatca ctaatatctg gtccgcattt ttgattgtgg acaggcgatg ggcaatcaca
    21181 aaactggttt ttccttccat cattgctaag aaggcttgtt ggattttttt ctctgtcaat
    21241 gtatcgactg agctggtagc ttcatctaag atcaacatag ggggattact gatcatcgtt
    21301 cgagcaatcg tcaacagttg gcgttgtcca tctgatatct ttaacccttg accgccaatc
    21361 ttagtatcta atttttccgg caaacgttct acaaattcat acatataaga ggcttttagg
    21421 gcatcattga tttctgcgtc acttgcttcc ggattcccaa aacgaagatt ttctcgcaat
    21481 gtactgtcaa atagccaagt atcttgtaac accattccaa aacttttacg taatgtatca
    21541 cgttggatag agcggatgtc atggtcatcg actgtaattg ttccttttgt tgtgtcataa
    21601 aaacgcatca gcaaattaac aagtgtggat tttccggccc ctgtttttcc tactatagca
    21661 atggtttgac ctggataagc agtaaaattg aaatcttcga tcaaacgctg cttggggtca
    21721 taagaaaaag aaacatgatc aaaagagact tttcctttga tatttttggg ttccaaggca
    21781 taggcatctg gcaaatcagg cttttcttct ggctgatcga tcaaatcaaa tgctcgttct
    21841 agaccagaaa aagcggtttg cagttgtgtc gtgattccag aaagttcgat aaatggttta
    21901 gaaaactgac ttgagtagat cgtaaagctg gaaatcacac caacagtgat tgacgaacca
    21961 ctcttcaatg ccaataggcc gccaactaaa ccaatcgata aataagcaag gtgatctaca
    22021 aaacgagaag acgggtttgt caaggaagaa gaaaattgtg cccgttgtcc tttttcatat
    22081 agatcagcat ttagcagttc aaattgctgt tgactagctt cttcttgctg aaaagctttc
    22141 acgattttct ggttaccgat tcgttcggtc acaaagcccg agatatcccc aataatcctt
    22201 tgctgtctat cgaaatttgt ttgtgaagca cgagcaacga tccaactcac aaggaaaata
    22261 attggtgtag aacaaagaac gaccaatgtc agaagtggac ttagacgcat cataaaaata
    22321 aacgaaagaa tgatgattgc cactccagaa aataattgat tgaaggccgc agaaattgca
    22381 atggaaatat tgtccatatc atttgtaaat cgactgacga tatttccgtg ggagttttga
    22441 tcataataac gaagtggcaa tcgattcaga tgagcaaatg catcttttct taattttgca
    22501 acggataagt aagctaaccg attgcttaac acttggatga gccattgact gactacgttg
    22561 attaaaacga taccaccgaa tagaataagt aaatggaaca gtcgattgaa gcggacctgt
    22621 ccttctccaa tcatttgatc gatactttga ccaatttgta acgtcatcac aactgttgca
    22681 atcccattga tgattcctag tatcacagct agccaaatgt cttttgcata ggcagtaagg
    22741 taaggaatga atcggcggag cgtctgcaag gataattttt ttactttcat aactattctt
    22801 cctcctgtga tgcgacgatt tcctgatatt ctgctgattg agcaagtaat tcttcatggg
    22861 taccctgagc agcaatctta ccttgatcca tcactaagat atgatgtgct tcttgaatag
    22921 agcggacacg ttgggagata ataatcactg tactgccaag ataagtctgt agcgccttac
    22981 gcaaatccaa gtctgtttga taatccaacg cacttaaaga gtcatctaaa atcagtaatg
    23041 ctggcttggc aatcaaagct cttgcaatcg tcagtcgctg tttttgtccg ccagagaaat
    23101 ttttcccatt ttccatgact tttgtatcta aaccatttgg aagctgacgg acaaattctt
    23161 ctgcctgagc gattttcaga gcttcccaac attctttttc tgtggcgtct ttcttacccc
    23221 attgaaggtt ttcacgaata gtcccggtaa atagtacaga agtttgggga acaagagcaa
    23281 tttgctgacg gagatgatcc agctgccaag aacgaacatc cattccgtcc attataactg
    23341 taccggaact gacatcatag aaacgcggaa tcaattgtgt caaagtcgtt ttcccgcttc
    23401 cggttggacc aatgattcca aggactgtat ttcgcttcag ctgaaatgta atattttgga
    23461 gagaaagacc agaatcagga gtataacgga agtcaacatg gtcaaaagcg ataattgctt
    23521 cagaagaaaa atcgggagta gtactgacct cagcttcaag aatcgaattt tctgtgtcta
    23581 gcacctcttt cacccgattt cctgaagctt cggcacgtgt gaagatcacg acgaggtttg
    23641 aaacaacgat cagtgccaaa agcatttgat tcatataatt gatcaaagca agaacttgtc
    23701 cttgttgcaa gctaccaata tttactttga tcccgccaac tgtcagcaaa cagatgatcc
    23761 cgacattcat gatcaaggtt gtagcaggtg ataatagggc agagatattg gaaacacgta
    23821 aataattgtt cgctagatca tttgtgcttt tatcgaactt ctctgtttct ttttttgtct
    23881 gcgcaaatgc gcggatgaca cgaacaccgc taagattctg actaacgtgt tcattgagct
    23941 gatctagttt ttcttgcact ttttggtaga gaggaacggt ttttttgatg ataaaaaata
    24001 aaatgattga gaaaataggc aataatgcta agaaaaacag acctacttcc cagtcgatca
    24061 caaaagccat gaccactgac ccgatactta aaaacggtgc tctgatcaat aaacgaatga
    24121 ccattgctaa agctagctga agctgattga tgtcgtttgt cattcgggtg atcaaggtat
    24181 ctgttccaaa atgattcaac tcgttgtgag agaaagtatt gatttttttg attagctgat
    24241 tacgtaactc tgtaccaaat ccttgtgaag ctactgaagc atagtattgg caaatgatag
    24301 cacaaatcag accaatcaca gacatagcga ccatccataa gcccatttca atgatttttc
    24361 ctcggtcatt catttttagt ccattatcga tcaaggaagc catcattaaa ggcaggacaa
    24421 gttcgaagac agcttcaaga aatttgaaga acgggcccaa aatgatttgc ttacgatagt
    24481 cttttgcata acgtaataac tgaatcatat gattcctcct attatttatt tgtccacaat
    24541 tgaaaaaaca agtactacca cattgtagct taggaaattt agaatgaaaa gagaacaagc
    24601 cttttcataa atgaaagttt tattatgaag aagctttaga aattgaatag actatttttt
    24661 ttaaaaaaaa gaaaatgaga aaacatgcca gtctcttcat tcataggaac gtctatttta
    24721 cttaattttt ctataaatga attctgcata aaaaatatat caagtaaatg tttatagatg
    24781 aaactctatt tacttctttt ttaatttgtt cttgcaatct tttttgctac gtaatttttg
    24841 taaaaaagtg ggttgagaga aatctaattg attttcaaag aaggagtatg aaaatgagaa
    24901 aaatatttat tcgtttattg tgggtactat cttagaggaa taaataatag tggagaaaac
    24961 tatggtttgg cgcagattct atcaggtttg atggaacgaa gacaacctcc cgacatcaag
    25021 tcaaaagcta cttgagattt tgatctgaaa ataaaaaaag aaaacaaggt aggaacatca
    25081 atgtttctac cttgttttcg taatcaatgg gaaaaaacta agagtggtgt acgtaatcaa
    25141 taaaaaggat ggtgacaaca gtacctcttt actctctgaa agcatcataa ctcgtttttc
    25201 ctcattatgc caataaattg ttgttatacc acatataagg atttgtaata gctaaaaaca
    25261 gacaggaaag ttgaaatctg tgaatcttat tttgtatgga aggatttata gaacgcaaaa
    25321 atcaagataa agatgaataa aaatcctgtt tcggctatat attgcgtatc tacgccaata
    25381 aaacgagttt gttctgtcat agccatataa agcaaaggca aaaatacaac tacagcgaga
    25441 taagatccga tgatttctcg aaaagttttc caggaagtat gtttcctgtt tttatattta
    25501 tccgatttca ttgaatagtc atagcctcct tattctttca tatgttgaaa ttccagtata
    25561 aaaactggaa ggaactgtac gttttttaga ataaaaatta taagggataa gtaggctgct
    25621 gtctataata agatatattt ttcaattctt tattaaagat tttattgaca aaatgaatcc
    25681 gttttctatg atggaggagg ggtgaataag ttgttgaaga aggaaatttt atgttactta
    25741 gagaaccaga cagccttttt cgatttagaa catatgaacg aggtctttac agcacaaagg
    25801 ttagctgatc attttggggt aaaaagaaac acagtcagtc attatttgaa ccagttaaat
    25861 gatgagcaac tactagtcaa aatcaattct cgaccagtga tttatttcca caaagaagct
    25921 tttgaaaaac aattttttaa gttacgcacg aatttttatt tttctatcga tgatctcaaa
    25981 gaggaacagc cttttttcgc gcaaccaaaa gacttattct cttttatgat cggatacgac
    26041 gccagtttga aagaaagtat cgaacaaatc aaaacagctc tttactatcc agatggcgga
    26101 ttaccacttt tgattacagg cgaaagtggc acaggtaaaa gttatttagt taatttggtc
    26161 tatcagtatt gtctgcttca tgatctgcta gaagattctg caccattcat cacttttaat
    26221 tgtgcacaat atgcagataa tcctgaactt ttgactagca atttgtttgg acatgttaag
    26281 ggagcgtaca ctggtgcaga agaaaataaa aaaggggctt ttgaagcagc agatggtggg
    26341 atcttgtttt tagacgaggt acatcgctta acaccagaag gtcaggaaaa actgttcacc
    26401 tatcttgatc aaggtgtgat ttatcgtatg ggagaaccta atttgtcacg ccggatcaaa
    26461 acacgtctct tttttgctac gactgaagag attactagtc atttcttaac aactttcatt
    26521 cgaagaatac ctatccgaat cgaactacct gcacttaatc agcgtagtcg taatgaacgg
    26581 ctagaactga tttactcttt ttttctcgaa gaacaaagaa aaatggggag ccctttgtca
    26641 gtcagtggac cagctttgtc acttttaaca agtcagaaat tatccggaaa cataggagag
    26701 ctgaaaaata tcgtcaaagt ttcagcagca aaagcatatg ctgaacagcg tgaacagcct
    26761 gaaatccatg tcacgatcca tcatttgcaa aaagaactac ttgcgcagcc tattactaaa
    26821 aatacagcac agcaaggaat ctatattacg caagaccaga ccttagagca attaatggag
    26881 aagcaacagc ccgaacagca gcgaatcgtt aaaagttttg agcaaatcct aattgatttc
    26941 aagaaaaata actgtctgct atattcttgc gaaggaaaat taaagcaaga agtgattcaa
    27001 ttatttgatt ttttgctgtt tgagaccagt agacaagaaa aacacgagct gctggtttat
    27061 tggacacaat ctatccgaga gacctttcga caaatggaaa ctgcctatca aatcaaattc
    27121 gatggaaaca gtgtctatgc cttgagttac tatctctatc agcgaagcac tatcaaatgg
    27181 ttaccggaag aacatgatat tatccaacta atcaaagaat tagaacaaca agtttctcag
    27241 tcttatccat ctagttatca ctatgtccaa cgaattctgg aattaagtaa gatcaaatta
    27301 gatattgaag acacaagtat ggatcggatt ttactgacga tctatctaaa aaaagcgaaa
    27361 tggtcaaaag aaaaacgact gccaaaagcg atgattgctg ctcacggtta tgcaactgct
    27421 agcagtatgg caaatgtagt aaatcgttta ttacaagagg atctatttga atcatttgat
    27481 atgccactag atgtcacacc acagcagatt gcttcagaaa tccttgatta ttgcgaaaac
    27541 agcgatgttt caaatggatt gatcatatta gtagacatgg gatctctgaa agaaatccat
    27601 cagtttttta aaaaacagtt atccgtaccg cttttgattt tgaataatgt gacgacacct
    27661 ttagcaatca cagtagggga atgcctgcaa aaaaatgtat cattagaaga gatagcagaa
    27721 gagactgttc gacagatcca gccagaatgg cgactgctct atccagagga aaacaaaccc
    27781 aaagcactca ttactacttg cttcactgga atcggtacgg cggtccactt aagtgaactg
    27841 ctagaaaaaa gcttacctac ggcttgtcag ttgaaaatca tcccatatga atatcagcaa
    27901 ttaaaagata agaaaaacag tgacccatta ttttccatat acgaagtcgt aggaatgatt
    27961 ggcaccacag atcctgatat caccaatatc gactatcttt cattagaaga cctcatctcg
    28021 ggggaaaaga tgtctgtact agctgaatgg ttggacacta ctatgaatgc ttcagagaag
    28081 gaaatattca atcagcgcat cattcgtaat ttttcattgg aaaaagtact ggattccgtg
    28141 actattctag atacagagaa ggtgatggga gaaatcgatc attttatgag agaattagag
    28201 gtgcagttga atcgaagcat cagcaatccc aaaaaattag cgttgtatgt ccatgtgagc
    28261 tgtctcattg aacgattgat ccgacaaatg ccaatcgaaa cctatcaagg attagagaaa
    28321 tggaagcagt gtcaaaaaga agggttatct gctattaaat ctgcgtttag tgtcattgaa
    28381 gagcattata gtgtcatgat ccccaattct gagattgcct atatctatga tattttgagt
    28441 gaagatacag agtttctctc gatagaagaa gaattttgaa cataagcaag ttgttgccac
    28501 taattttggc atgcaacttg cttttttagt atgtgtaagt gaaaagagga gatgaaaaag
    28561 tggatagaga aattatctta gcttcccatg gaaaatttgc ttcagggata ttagattcat
    28621 tagagctgat ctatgggaaa aatcattcta ttactgtatt cgattgctat actgatgaga
    28681 attttgattt agcggaaaca gtaaggcagc tttttatgag gtacaaagat aaagaaatca
    28741 ttgttctgac ggatcttttt ggcggaagtg tcaacaacga attcttacaa tatatcaatc
    28801 gggatcatgt ctatctcgtt gccggattga atttgccact attgattgag ctagtatctc
    28861 ggttggacgc tgaagtagag acaactgttt tgatccagca ggtgctaact gattcaaaaa
    28921 aaatgatcca gttttgtaac gagcggctca atcagaaaat agaagaagac gaattttagg
    28981 aggaagaaaa atgattgtat tgacaagagt cgaccatcgg ttattacacg gacaagtagc
    29041 tttttcatgg acacaaacaa taggcgcaga ctgtattttg attgctaatg atgatgtacc
    29101 tacgaatgag atacgaaaga caacgatcaa attagccaag ccacaaggag tcaaactagt
    29161 gatcaaatca attgatgact cgattgccgc gttgaaaagc ggggtgacag ataaatataa
    29221 gttattcatc gtagtggaat cgatcgagga tgcatataag ctggcagaag cgtatccaga
    29281 aatcaaaacc atcaacttag gagggatcaa ggcaaaacct ggtactcgca gcatcggaaa
    29341 agcggtaaat attttaccag aagaggagga acgcttgaaa cgattaattg acaaacaaat
    29401 agaagtagaa atccgtcaag taccagcaga taaaaaagtg gatgtaagag aagttttgta
    29461 agaaaggaag aacctcaatg attgtacaag cagtcttatt aggaattgtt gcatttgtcg
    29521 cacaatcaga atatgcacta gggacatcgt tgctttctcg tccgattgtg acggggctgt
    29581 ttacaggaat cgtgttaggt gatgtaaaaa ctgggatcat tatgggcgca actttagagt
    29641 tagcatttat cggatcgttc tcagtaggtg cttcgattcc acctgatgtt gtgaccggtg
    29701 ggattttagg gacggctttt gctattacag ctggagccgg tacagaaacc gcgcttttac
    29761 taggtttgcc gattgctacg ttgacattga tattgaaaaa tatttactta gggcttttga
    29821 ttccaattat gaaccataaa gcagacaatt atgcagaaga aggaaattat aaaggagtcg
    29881 agcatatgca cttgcttgcc ggtatcggtc tttccttgat gcttggtgtt gtggtaatgg
    29941 tttcttatat ggtgggaagc aatacgatcg gaaatctatt aaatatgatt cctgacttcg
    30001 ttcaaaaggg gttgtcagta gctacagggt tgattccagc tcttggtttt gcgatgcttg
    30061 ctcgtttgct gatcaacaaa caagttgcac catatttttt cttaggtttt gctatagctt
    30121 cttacttaga gattcctgtg accggagtag ctatttttgg tgcgatttta gcagttgtgg
    30181 tagtcaatat tatgaatgtc cgtcaactac cacttcaaac aactgcaggg gaggtagaag
    30241 aagatgaaga attctgagat caaaaacagc aaaataacga aaaaagagct aaatcacgta
    30301 ttttggcgtt cttttcaaat ggagttttct tggaattatg aacgtcagat gaatatggct
    30361 tatgtttatg caatgattcc gattttgaaa aagctatatc agtcgaaaga agaaatggca
    30421 gcagctttga aacggcatct agagtttttt aacacgaccc cacatatcgt tacactgatt
    30481 ttaggaatca cggctgcaat ggaggaagaa aataaggatg atcctgaatt tgatgtgact
    30541 gcgatcgata gtatcaaaac atctttgatg ggacctcttg cagggttagg agattctttc
    30601 ttttggggaa ctttgcgatt gattgccaca ggtgtgggta cctctttagc catgcaagga
    30661 aatattttag gccctatctt gttcattttg attttcaata ttccgcacat tctgtttcgc
    30721 tatctagcaa caggttgggg atatcgctta ggaacgggtt ttttgaaaaa gatccaggca
    30781 aacggtatga tggaaagttt gacattaggc gcgtctatta ttggactgat ggtcgttgga
    30841 gcaatgactg ccacgatgat caccatcaat attcctttaa aaatcggttc aggagaaaat
    30901 gctgtgactg ttcaaagtat ttttgatgat atcgttccaa atatcttatg tcttggagca
    30961 tttggcatag tgttttatct attgaagaaa gaagtgaaac cattaacgat cttgatcgga
    31021 ctagctttct ttggaatttt tggttcgtgg atagggattt tttaaaaaag gagcagagaa
    31081 aatgtttacg atgcaagatt atatctatga agaaaaggaa gtactaagta cgatcttgaa
    31141 aaagaatgat ttttcgacaa gagaacatat gaaaaaaaca gtgaatttac tgatcttagc
    31201 aacgggttca tcttataacg cttgtttagc agcgaagcca gcattggaat cttatggtga
    31261 tcttactgtc gatattcaag aaccttttta ttttttcaat tatggaaaac tttctccttc
    31321 aatcgatact gtgattgctg tgtcacaaag cgggaaaagt gcttctactg ttgaagcagt
    31381 aaaaatgata caaaaacaag ggttacctgt tgttgctatc acaaatgacg tgcaaagtcc
    31441 acttgcttta gaagctgcac aaattattga tttaggtgcc ggggtagaat cagtaggctt
    31501 cgttacaaaa ggctattctg cgactgtttt acagttacta ctcttaggga taggaattgg
    31561 aataagtaaa aataaaatca gcaaaaaaat agaacaagac tacatgcaac agttgcgcaa
    31621 aataatcaac catttaccag cgattattca aaaaacggaa gaattttttg atggatatca
    31681 aagtttattt cgtttagcac agcgtttcgt caccattgga tatggtccaa actggggaac
    31741 agctaaagaa gcagagacga aattgactga aacaatccgc gttccgtcac aaggatttga
    31801 gttagaagct tatatgcacg gcccatacct ggaggcagat gcttcgcatt tgctattctt
    31861 tattgaaggg gaaagtgtaa ataaggaacg ttcgcaaaag ttgcaaagat atatgagtcg
    31921 gtacgttgga gagactctca ccattaccac aaaaaaagca agaaacgaga aaacacttgg
    31981 attagcaata gaatgtgatg aatatctgtc tgtattagcg cttgtcgttc cgtttcaact
    32041 attcgcttat aaaaccgcag tagctaaagg tattgacttg aacaaaaaga tttttgaaga
    32101 ctttgataca gtcttgaaaa gtaaattata agaggtggaa atcatgctga aattcaatga
    32161 agaagaacaa atcaaagcaa taaaaggcgc actagcttta cgtccgcaag tagaagaaat
    32221 catcgataaa ctttatgcgg aaaaatttga cgctgtctat tatctaggaa tcggtggaac
    32281 gtatgcttcc tcgatgcaag ctgtcactta tatgaatggg aaaagcaact tgcctgtctt
    32341 tgtacagcat gctgcagaat attacactac tggaaacaaa agattaacaa aagattctat
    32401 cgttattttg tcctctgtta ccggtacaac tcaagaagta gtgaaagcag tagaacaaat
    32461 caagaaagta ggagcgacac tgattggatt tatcgataaa gcgaacagta agttgtctca
    32521 gctatgcgat tttgtggtca cttatccagc tcctggaaca gaacaaatca aattttttat
    32581 ggcagcagat cgattgatgt atttgaatgg agaattcgaa gcttattcag aatactatga
    32641 acagctcgaa cgttatttac caacagggtt agtggaagca gagaaaaaag cagatgcatt
    32701 tggcttatca tttgcagaaa aacatcgacg tgatagtatg cattatttta ttggagcagg
    32761 gaatcaatgg ggagctgttt attcatatgc catgtgttac tgggaagaac aaagctggct
    32821 tccatcgaaa tctatccatg ctgccgagtt tcttcacggg acgttagaga tcgtagaaga
    32881 aacaacccca gtcacattat ttttaggcga agatgaacag agagtgttat ctgaacgtgt
    32941 ggctaaactt ttgccaaaaa tttgcagcaa ttatacattg atagacacaa aagactatcc
    33001 agtagaaggt atcagtgaaa aatatcgcgg acgtgttttg tctttcttat tgatgcatgt
    33061 agtgacacaa cgcatcgatg ctcatgtgga gcagttgaac tgccatccat tagagatacg
    33121 ccgctactat cgtcagtttg attattagga tagactggat aaaaagaata taaaaaataa
    33181 agagagcagc gataactgct ccctttattt ttttaaaata ttggcatcaa ttacgttata
    33241 aaacacattt tttgcattat ctacagttca acttataatc tgtttaatgg gacatgtggg
    33301 tgccaaccat tttttgttat gcaatagtac tatttagttg ttgcatggat ccgtagtaaa
    33361 agtccaagta caacgagttg cgccagttta catagcgttt tgtatccaga atgttgacta
    33421 aaacaaaagt tcctatgtca accgtcaaca gagacaatct gtccgttgca ggacctgaca
    33481 gatttagaaa tgttcaatct gtctcttatg tattttaaat caatactcac taggagaagt
    33541 ttcctaacct cctaatagta atgctggtag taacattgtc aaaactgctt cctcttagga
    33601 acaagcaaag cataacgagt gtaaaaataa aatgtagact attgtaacat atcattgatt
    33661 atttcaagta aaaacgataa aagaagtaaa caaacactta aaaacaatgg aaattagtcc
    33721 caactttaag aaatgtatac tataatggaa attatcaatt atttatttgg aggaatatcc
    33781 atgaaacaaa aaatcgcagt tcttggtcct ggatcttggg gcactgcttt agcacaaaca
    33841 ttggcagaaa acgggcatga tgtccgtatt tggggaaatg tacctgaaca gattgatgaa
    33901 atcaataagt atcatacaaa tcagcatttt ttacctgatt tgacgatccc agaatcgatt
    33961 atcggatata aagaattggc agaagcagtg gataacgcag atgctatttt atttgttgtt
    34021 ccaacaaaag cgattcgttc agtcgcacag gaacttattg gtaaaatgaa tactaagcca
    34081 atcattatac atgcaagtaa aggactagaa caagatacgc ataaacgaat ctcagaagtt
    34141 ttggctgaag aaattccaga agaaaaaaga caggcaattg ttgtattatc tggtcctagc
    34201 catgctgagg aagtggcagt acatgatatc acaacaatta cagctgcaag tattgatcaa
    34261 aaagcagcag cctatgtaca aaaactgttc atgaatgatt atttcaggat ttatacaaat
    34321 aatgatgtga ttggcgtaga aactggtgca gcactgaaaa atatcattgc aattggtgcc
    34381 ggcgctatcc atggattagg attcggagat gatgcaaaag cagcaatcat gactcgagga
    34441 ttggcagaaa tcagccgtct tggtgtcgcg atgggtgcca atcctctgac atttatcggt
    34501 ttgagtggtg tgggggactt gatcgttact tgtacaagtg ttcattctcg caattggcgt
    34561 gccggtaact tgttaggaca gggacataag ctggaagaag ttctagaaaa catgggaatg
    34621 gtcgttgagg gtgtggcaac gacaaaagca gcagtagagc tagctcaaca gctaggtgtt
    34681 gagatgccaa ttactcaaac aatctataat gttttgtata atggagaaga tatcaaaaaa
    34741 gcagcaaaag aaatcatgtt acgtgacgga aaaatggaga atgaattttc tcttcgttaa
    34801 atagatgatc aatagttaat cgtcgtttag gaggaacagc aagtgaaggt caaaaaagca
    34861 gtcattcctg ccgctgggct aggaacacgt tttttgccgg caacaaaagc catggcaaaa
    34921 gaaatgcttc caatcgtgga taaaccaacg atccagttta ttgtggaaga agcattggat
    34981 tcgggaatcg aagacatctt gatcgtaacg ggaaaagaaa aaagacccat tgaagatcac
    35041 tttgatgcaa atatcgaatt ggaaaacaat ttgcgggaaa aggaaaaaac agaattactc
    35101 gctttagttg aagaaacgac tcaagtcaat cttcacttca tccgtcaatc tcatccaaga
    35161 ggactggggg atgccgtgct tcaagcaaaa gcatttatag gaaatgaacc gtttgtcgtc
    35221 atgctggggg atgatttgat gaaagatgat atcccattga ctcaacaatt gatgatggat
    35281 tatgaagaaa cacaagcttc cgctgttgcc gtcatgcgtg taccagaaaa tgaaacatct
    35341 aaatacggaa ttattgatcc taaaacagat agcgaaaagg gtcgttgcag agtaaaaggg
    35401 tttgtagaaa aacctgaaat gggaaaagca ccaagtaatt tagccattat cggacgttat
    35461 ctactgactc ctaaaatatt tgagatatta gaaactcaag aaccaggagc aggaaacgag
    35521 atacagctaa cggatgcact tcagactctt aaccagacag aggcggtcta tgcgagagag
    35581 tttaaaggaa aaagatacga cgtaggcgat aagttaggat atatgaagac aaatattgaa
    35641 tatggacttc aacattcgga aattgggact tcattaagtg catatattat ccagttgagt
    35701 aaaaagctaa gaacagaaag ttaactggaa ataagtggcc tgctgagaat gaaaggctat
    35761 ttgttattaa agcggcagct tgtgcgtcat ttgcgcaact gtcgttttag ttttttgact
    35821 ctagatcagt tgagtcgtgg aaaacgaaag atagaaaaag actttcgtga atagattcag
    35881 aaaatattat gctaatggtt taattttttt ttaagttgta taaaagaaaa tgattacata
    35941 agagaaatga aagccaagcc agaagattca tagtagaata aaaaggcgaa ttttttaatt
    36001 ataaaaaaag gtgtgtgttc actatgggaa aattagtcgc tgttgcacag tcgctgcttg
    36061 atatactcaa gtggctgatg gaaggaagca attggatatt tgtgttgcca ctattgctta
    36121 ttagtctatt tatcatgttt cgcatggtca gaaaaaaaga aacgtttctg atttttatct
    36181 ggtatgcagc atccgttggg gttgctacct tgatggttga attggcgtta ggtagttggg
    36241 aagcttgcgt atttgcttta ttttttgctg tactgtatct aatcatttat atcccatata
    36301 tgaaaagaaa gtctcggata ggcagaaaag gtagacatac aactactttt tctagtacag
    36361 attctctcga acaaagtaga agaacgagaa gaagacggta atatttagta ggtatacgca
    36421 aaaaaagata aaataatgga taaactattg agatgagaga tttatttaat tggtggaaaa
    36481 aagctttttt cacttatata aaagaatctt ttttaaagga atgcttgttg tatcgggata
    36541 agccattcct ttttttatgt tatttatata tatataaatc ataccaatgt ttttttgtat
    36601 tttcttgctt gcacttggat aagagattac ttacaataaa ttcagataga aacagctgaa
    36661 taaaaaaagg ctccctgacc cttagttggc gctaagaatc agggaatgac cagtcacaca
    36721 catacaccct gaccgatcat tttgccatag tcaatgcagt gcatcgacct aatttattgt
    36781 acctaatcta gggtgaaaat tctaccccta tgtagatatt ttccatggtc tgcacgttgt
    36841 tttatttgct atgtcaaggt attgggcgta ttcgttcaat gccttttttg tgtttgaaac
    36901 agcaaagacc acatgtgtta ctgtctaact actgtttttt tatgtacttc cttagattag
    36961 gcagctgttt ctattcatgt caagtatagc taggcgggag agataaatga gtttatgtta
    37021 ttttgactat tatcaccaat tggaagagaa attaaggata gaagagccgc tgatgcttca
    37081 agctggcact tggatcgcga aacaaattaa tcaaggtggt agattgcaga tatatgctag
    37141 ccgcacacta agtggtgtag catttgaatt ttgggatcaa accccggatc ttgtaccaag
    37201 tatattgatt gaaaatccag ccggaggtgt ctatgaaacg ctagaaggtg caggacaggc
    37261 aattattgat cagctttctg tcaaatcaga agacattttt cttcttcttt cgaatgaagg
    37321 aagaaacccg gcaatcatcg aactagctca gtggatcaaa gaaaatggtc atccattaat
    37381 cattgttact ggatttgatt tgtcacgaag tatcaaatcg caacatagca gtggtttgcg
    37441 attatttgaa tttgctgatt tggttttgga caaccacgcc aatttacatg atgcagtctt
    37501 gactttgcca aatctagatc cagcgatctg cggaacagcc tctcttgcaa cgatcttttt
    37561 gctgcagcaa gttttgtatt ttacagcaaa acagctagtc caggacacaa gtggaaaata
    37621 gttatccaca tgttgacaaa gttccttaaa aaaataatgt tccacataaa aatggagcgt
    37681 ttgaaaaaaa gaaaacgatt attaatgagg attaacaacg actacttttt ttgttttagt
    37741 tattttaaga tggatcatct ttgattttaa gcttgttttg tttaaagttt gttattttta
    37801 taagttgttt cacagttatg agaaatgagt tataagaata tgtagtgtca gaaaaataaa
    37861 aagtagtgga aaaagagaca agaaagaatc catatggatt ctttcttgtc tcttaataca
    37921 cgttgatgaa agagtcttcc ccaaaactct ttacaaagta a
//
LOCUS       DAJSMK010000017        36914 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.017, whole genome shotgun sequence.
ACCESSION   DAJSMK010000017 DAJSMK010000000
VERSION     DAJSMK010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.017"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..261
                     /locus_tag="ON488_000893"
     CDS             <1..261
                     /locus_tag="ON488_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3231106.1"
                     /translation="DKDPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPY
                     TNGKIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIKVR"
     gene            complement(371..1867)
                     /gene="lysS"
                     /locus_tag="ON488_000894"
     CDS             complement(371..1867)
                     /gene="lysS"
                     /locus_tag="ON488_000894"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HCR3231107.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1978..2982)
                     /gene="dusB"
                     /locus_tag="ON488_000895"
     CDS             complement(1978..2982)
                     /gene="dusB"
                     /locus_tag="ON488_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HCR3231108.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2983..3870)
                     /gene="hslO"
                     /locus_tag="ON488_000896"
     CDS             complement(2983..3870)
                     /gene="hslO"
                     /locus_tag="ON488_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HCR3231109.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(4087..6198)
                     /gene="ftsH"
                     /locus_tag="ON488_000897"
     CDS             complement(4087..6198)
                     /gene="ftsH"
                     /locus_tag="ON488_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HCR3231110.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(6288..6833)
                     /gene="hpt"
                     /locus_tag="ON488_000898"
     CDS             complement(6288..6833)
                     /gene="hpt"
                     /locus_tag="ON488_000898"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HCR3231111.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6833..8278)
                     /gene="tilS"
                     /locus_tag="ON488_000899"
     CDS             complement(6833..8278)
                     /gene="tilS"
                     /locus_tag="ON488_000899"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HCR3231112.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8398..8868)
                     /locus_tag="ON488_000900"
     CDS             complement(8398..8868)
                     /locus_tag="ON488_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HCR3231113.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8914..9339)
                     /locus_tag="ON488_000901"
     CDS             complement(8914..9339)
                     /locus_tag="ON488_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HCR3231114.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9406..9675)
                     /locus_tag="ON488_000902"
     CDS             complement(9406..9675)
                     /locus_tag="ON488_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HCR3231115.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9686..11281)
                     /locus_tag="ON488_000903"
     CDS             complement(9686..11281)
                     /locus_tag="ON488_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HCR3231116.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(11296..14817)
                     /gene="mfd"
                     /locus_tag="ON488_000904"
     CDS             complement(11296..14817)
                     /gene="mfd"
                     /locus_tag="ON488_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HCR3231117.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14834..15394)
                     /locus_tag="ON488_000905"
     CDS             complement(14834..15394)
                     /locus_tag="ON488_000905"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HCR3231118.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15747..16721
                     /locus_tag="ON488_000906"
     CDS             15747..16721
                     /locus_tag="ON488_000906"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCR3231119.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16891..18291
                     /locus_tag="ON488_000907"
     CDS             16891..18291
                     /locus_tag="ON488_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HCR3231120.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18369..19091)
                     /locus_tag="ON488_000908"
     CDS             complement(18369..19091)
                     /locus_tag="ON488_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3231121.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(19170..19676)
                     /locus_tag="ON488_000909"
     CDS             complement(19170..19676)
                     /locus_tag="ON488_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCR3231122.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19799..21598
                     /locus_tag="ON488_000910"
     CDS             19799..21598
                     /locus_tag="ON488_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HCR3231123.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21666..23240)
                     /locus_tag="ON488_000911"
     CDS             complement(21666..23240)
                     /locus_tag="ON488_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCR3231124.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23495..24004)
                     /gene="mreD"
                     /locus_tag="ON488_000912"
     CDS             complement(23495..24004)
                     /gene="mreD"
                     /locus_tag="ON488_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HCR3231125.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(24008..24862)
                     /gene="mreC"
                     /locus_tag="ON488_000913"
     CDS             complement(24008..24862)
                     /gene="mreC"
                     /locus_tag="ON488_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HCR3231126.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(25017..25655)
                     /locus_tag="ON488_000914"
     CDS             complement(25017..25655)
                     /locus_tag="ON488_000914"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HCR3231127.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25656..26306)
                     /locus_tag="ON488_000915"
     CDS             complement(25656..26306)
                     /locus_tag="ON488_000915"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HCR3231128.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(26319..27218)
                     /gene="rsgA"
                     /locus_tag="ON488_000916"
     CDS             complement(26319..27218)
                     /gene="rsgA"
                     /locus_tag="ON488_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HCR3231129.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27383..29452)
                     /gene="pknB"
                     /locus_tag="ON488_000917"
     CDS             complement(27383..29452)
                     /gene="pknB"
                     /locus_tag="ON488_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HCR3231130.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29449..30189)
                     /locus_tag="ON488_000918"
     CDS             complement(29449..30189)
                     /locus_tag="ON488_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HCR3231131.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(30202..31560)
                     /gene="rsmB"
                     /locus_tag="ON488_000919"
     CDS             complement(30202..31560)
                     /gene="rsmB"
                     /locus_tag="ON488_000919"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HCR3231132.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31560..32498)
                     /locus_tag="ON488_000920"
     CDS             complement(31560..32498)
                     /locus_tag="ON488_000920"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HCR3231133.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32491..32982)
                     /gene="def"
                     /locus_tag="ON488_000921"
     CDS             complement(32491..32982)
                     /gene="def"
                     /locus_tag="ON488_000921"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCR3231134.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32997..35405)
                     /gene="priA"
                     /locus_tag="ON488_000922"
     CDS             complement(32997..35405)
                     /gene="priA"
                     /locus_tag="ON488_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HCR3231135.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35658..35963)
                     /locus_tag="ON488_000923"
     CDS             complement(35658..35963)
                     /locus_tag="ON488_000923"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HCR3231136.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35968..36582)
                     /gene="gmk"
                     /locus_tag="ON488_000924"
     CDS             complement(35968..36582)
                     /gene="gmk"
                     /locus_tag="ON488_000924"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HCR3231137.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT        10012 a         8060 c         6766 g        12076 t
ORIGIN      
        1 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
       61 ggctttcggg aaaagctcca aaaccttctg acctatgaag aaggcatcac caacgcgatg
      121 atctatcctt acaccaatgg aaaaatagaa gcgaagaata cccatataaa gacaatgaaa
      181 cgagtatcct acggatttaa atcatttgag aacatgagaa ttagaatctt tttgatcaat
      241 caattaatca aagtaagata acaaaaaatc tgagccagaa tgaggttcat tctgacccag
      301 atttgatttt gtacaaccca tcagtcctta ttgacaaaga gccggaattc cttagacagc
      361 ttttattcga ttatctcatt gttgggaata gcaaaacatc ccgaattgat tgtgcatcag
      421 ttagcaacat tactaatctg tcgatcccga tgcctagacc accagttggc ggcataccgt
      481 attctaaggc ttccaagaag tcttcgtcta caccgtgagc ttcgtcattt cctagttcac
      541 gttctttttc ttgcgcttcg aatctttctc tttgatcaat tggatcgttc agttctgtaa
      601 aggcattagc aaattcgcgc cccactatga atagttcgaa tcgatctgtg aatcgaggat
      661 cttctggatt tttcttcgct aaaggcgaaa cttcgactgg atgtccgtat acaaacgtcg
      721 gttgtgtcaa tgtttcttca acaaatgttt caaagaattc attgataaca tgtccgacac
      781 ccatagcttc ggttacttct acattgtgtt tttcggctaa agctaatgct tcttccaatg
      841 tcatttcttg ccagaagtct acaccagttt gttctttgat tgcatctacc atatggatgc
      901 gtttaaagtc actttctaag tcgacagctt gtccatcata tgtgattttt gctgttccta
      961 gtactttttc agctgcgtta cggataatac cttctgtcag attcattaca tcattgaaat
     1021 cagtatatgc tgtgtatgct tctaacatcg taaattctgg attatgtgta gtatcaattc
     1081 cttcattacg gaaaacgcgg ccgatttcat aaactttttc cattccgcca acaattagtc
     1141 gttttaaatg aagttctagc gcaatacgca aatataaatc aatgtccagt gcattatgat
     1201 gcgtgataaa tgggcgtgcg gcagctccac ctgcctcatt gtgcaatact ggtgtttcta
     1261 cttcaatata gccattgcca tctaaatagc gacggatttc gctgataatt tggcttcgtt
     1321 tcataaatcg gtcaaagctt tcgcgattac tgattaaatc caagtagcgt tgtctgtagc
     1381 gttgttcaat attcgttaag ccatggtatt tatctggcag tggacgaagt gcttttgaca
     1441 aaatcgtgat ttctgaagct ttgatagaaa cttcgcctgt gtctgttttc atgatttgtc
     1501 cagttacacc aaagaaatct ccaaggtctg catgtttgaa tacttcatag gcctcatcac
     1561 ctacttggtc ttttcttaca taaatttgaa tttggccttc acgatcttgt agatgcgcaa
     1621 atccagtttt cccttttcct cggcgagtca tcatacgacc agctacacta gcggtcaatc
     1681 ccatttctgc tagttcttct tttgttcttg gatcaaatag ttcatgcaat tcttctgagt
     1741 tgtgcgtgcg ttcaaatcgt tttccaaatg gatcgattcc atcttcacgc aattgttcca
     1801 ttttttgacg acgtacaagc atttgatcat ttaaatcttc tacttgatgt tgttgttcct
     1861 gtgtcacaaa agttcctcca ttctcatgtt aatctctttc ctataatgcc aatgaaacac
     1921 aaaaaaagca agccgaactt ggaatttcgg cttgaaaatt cacgaaaaac ttagaaatca
     1981 caacgtttgt ttcaatagta ctttttccgc tttttctaca aattgatcca gcaggtcatt
     2041 gatttcttgc tgtttttctg tctgattgat tgctactttc actttcgctg ctcgaggaat
     2101 cccttttaaa taataagccg catgtgttct gaattctcta caagctactt tttctccttt
     2161 gagatctgct aagcgttgta aatgaagttt agctgtagca attttttcgg ctggtgttgg
     2221 ttcaggaatc agttctcctg tttcgagata atgctgtgtg cggtgaatca tccatggatt
     2281 gcccagcgct gcacgaccaa tcatcacacc gtctgcaccg acatagtcaa gcatccattt
     2341 tgcatcttct ggcgttttga catccccgtt ccccataaat gggatcgtca aatgtttttt
     2401 cacttctttc aatacttccc agtccgcttt tccttcatac atctgaaccc gtgtacgtcc
     2461 atgcatagcg atggcacttg ctccagctga ttgtgctgct aatgcatttt ctacagcaaa
     2521 gacgtgctct tcatcccaac caatacgcat cttgattgtt actgggatat ttactgctga
     2581 agaaacagct tggaccattt cgtatacttt ctcaggatct aaaagccatt ttgctcctgc
     2641 ttctgctttg attactttat ttactggaca gcccatattg atatctatta tatcggcagc
     2701 tgtgttttct tcgacaaatt gagcagcttc aactagacta tctttatttc cgccaaatat
     2761 ctgtaaactt aatggatgtt ctgtttcttc aatgtggagc atctctaaag tttttttgtt
     2821 tctgaaatga ataccttggt cactgatcat ttcacatacg actaagcccg caccaaattc
     2881 tttgacagtg actcgaaatg ctgaatttgt tattccagcc atcggtgcaa caacgacacg
     2941 attagggatt tccacattgc caattttcca tgtgtgttcc acttaaatcc ctcctaaggc
     3001 ttctttcttc aatccatcta attcttcttc gctatacttg tatttgttat tacagaaaga
     3061 acaaaccgct tctgcaccgt gatcttcgtc tatcattgct tggatttctt ctgcacctaa
     3121 cgcgataatt gcttctgcaa atttttcttt tgaacagtca catttgaatt gaacaggcat
     3181 tttttccaaa atgttcaatt cttctgtacc aagcaatcct ttcaatattt cttctggtgt
     3241 ctgtccttca tctaagaggg tagagattct tggtgtcgtt tttaattgtt cttcgatctt
     3301 gctgattgtt tcttcatcgg cacctggcat gatttggatc atgaatcctc ccgccgtctt
     3361 gatgctgtcg tcagtattga ccaatacact cagtccaaca gctgaaggga tttgttctga
     3421 gatagcaaga tagtaagtaa aatcttcagc gatttctcca gaaacaatcg gcgtttgccc
     3481 agaaaaaggt tcttttaatc ctaagtcttt tgtgacagta aacattcctt gtgttccaac
     3541 tgctccccgc acatcgattt taccttcact atttagagga agactgagat gcggattttt
     3601 gatgtaacct ttcacatctc cctttccatt tgcatctact acaattcctg ttgctggacc
     3661 atcgccttgg attcgaacag ttagtttgtc ttctcctttg agcgtcgcac caagtagcag
     3721 actaccgacc aatgtccgtc ccaaagcagc tgaggaggtg tgccaagtat catgacgtct
     3781 ttgtgcctcc gctacggtat ttgttgcttg aacggcgtat gctcggacga atccgtcgtg
     3841 agcaagtgcc ttaaccaaat aatctttcat ttgttatgta ctcctttttc cgtttttaaa
     3901 ctcatagtga atcatactag caactactgc ttttttcaac tttggaatgc ttcttttaaa
     3961 aataattcag aatcatctag aaaacaggac atcaccctat ttacaactta aataaagaaa
     4021 tctcccgaaa accggttttt gttccggttt tcgggagtca tatcagatca attgacctat
     4081 atttttttat ttgtattgat cgtctgaatg attatcttct gattgttgag aatctgaatc
     4141 atgttctgct ttattttcct cattcagttc atgttttgct tcttcaaaat cacgtttttc
     4201 ttccgcttgt ttttcagcgt ctttttcttc caaagcacgt tttgcttctt caaaagtttt
     4261 cgcttctttt tcgcttggat aatcatttga ctcagtacct tcaggcatca caccgtgttc
     4321 aaacaatgac ttgattgctt tggcatccaa tgtttcgaat tccaaaagtt tttcagcaat
     4381 cagtttatgc tgtgcacgat gagcttcgat gatttctcga gctttatcat gagcttccat
     4441 caagattttt cgtacttctt gatcaatctc gaaagcgact tgttccgagt aagcttttgt
     4501 ttgaccatag tcgcggccaa caaacacttg atggtttcct tcatattgaa caggacctaa
     4561 acgatcactc attccatatt ctgttaccat gcttcgtgct agagctgtcg cttgctcaaa
     4621 gtcattggaa gcaccagttg attggacatt gaagatgatt tcttcagctg tacgtccacc
     4681 aagtaagcct acgatttgtt caaacatatc ttctttcgtc atcaagaact gatcttcttt
     4741 tggtaaagcg atcatatatc cgccggcgcg tccgcgaggg atgatcgtta ctttgtggac
     4801 gacccgagcg cgactcaata ctaatccgac aatcgtatga ccagcttcgt gataagcaac
     4861 catttcgcgt tcttttttgc tgattacgcg atctttttta gctggacctg caatcacgcg
     4921 atcttccgct tcatcgatat cagaagcatc gattttcttt ttatttcttc tagcagctac
     4981 taacgctgct tcattcaaga cattttctaa atctgctccg gcaaaacctg gtgtctgttg
     5041 agccacaact ttcaagtcaa cgtcatctgc catcggttta ttccgtgcat ggactcgcaa
     5101 gattgcttca cgacctttta catctggacg tccaactaaa atctggcggt caaaacggcc
     5161 tggacgtagt aacgctgggt ctagtacatc agaacggttg gttgcagcaa tgacgattac
     5221 tccttcattt ccgtcgaagc catccatttc tacaagcaat tggttcaatg tttgttcgcg
     5281 ttcatcatgt ccgccgccca taccggcacc acgttgacga cctaccgcat caatttcatc
     5341 aatgaaaatg atagctggtg cgtttttctt cgctgtttca aacaaatcac gaacacgact
     5401 tgctccaaca ccgacaaaca tttctacgaa atcagaaccc gagatcgagt aaaacggtac
     5461 tccagcttct ccggcaacag cttttgctaa taaggtttta cctgttcctg gaggtccttc
     5521 taaaagtaca cctgccggga tacgggcacc taattcaaca aatcggcgag gatctttcag
     5581 aaattcaaca acttcaacta gttcttgttt ttcttcttcc gcacccgcta catcagaaaa
     5641 acgtacgcga ttagcttttt tgtctgcttc tttggctttt gatttaccaa agttcatgac
     5701 acggccgcca ccgccaccgc cgccgccttg ttgtcccatc atcatgtaaa agaaaaagat
     5761 gatgattacg attggcaaga agctaagcaa tagggaaacc catataccgc tgcttgattc
     5821 ttcttttact gttgtagcaa ctttgttttc ttttgccagt tctgttactt ggctcaatgt
     5881 tgtatcattt ggcaaaatga ttgttgtgaa atgggtagta gtcgtatctg ttgaacctaa
     5941 gatagctaac ccaccgctgt tagcgacggt ctgctgttct ttgtattcac cagtgatctt
     6001 atatacacca tttgcaggct gcacttcaaa ttctttgatc ttgcctgctt gtagttgttc
     6061 tgtgaatttt gagtactcga tatctgacga tcgctggccg ttattaccaa aaatgaaata
     6121 aacgaccatt accatcgcta agattacgag gacataatac aaggcatttt tcatcatgcc
     6181 gttgttcttt ttgttcatag ttgccctccc taagcgtcaa tttaatttaa cagtttttta
     6241 tcaatcctga ccattctatt gtaccataat ttaattgaga tacagcatta atttgattga
     6301 taaacactag gtttcaatac accgatgtac ggaaggttac gatatgcttc tgcataatcc
     6361 aagccataac cgaccacaaa ttcatttggt acgttgaagc caacataatc tgcttcgata
     6421 tttactactc ttccttcagg tttgtcaagt agtgtaacaa ttttgactga ttttgctttg
     6481 cggtatttga aaagatccac taaataagca agtgttcttc cgctgtcaat gatatcttca
     6541 acgatcaaca gatcgcgacc ttctacattc gtatctaagt ctttgacgat ttttacttcc
     6601 cctgacgaga ctgttgcatt cccgtagctt gaaacatcca tgaaatccaa ttccaaatac
     6661 gtatcgatag aacgaacgat atctgccatg aatggtaccg ctccttttaa gacacctact
     6721 actaggggat tggtgttttg gtaaatttct gttaactctt tgcctagttc tttgcaacga
     6781 acttgtatct cttcttgtga gatcaaaatt ctctcaatat ccttttccaa catcaggttc
     6841 tccttccaat tgcttctttt tgatatttgt aaagaagtat gtagtgtatt ttatcagttt
     6901 cttcacgaat actcaaatat gaaaaggcaa aaggtatcaa gctatatata tttcttttgg
     6961 catctgtaat gatccaagca tgctgccttt gtgaattagg tactttctga tcgataaaat
     7021 atctagatac tttttttgtg agattctctg ttaatttaat gcggtctcct gcttttcttt
     7081 tttcgacata cagttgcaca tcagcaggaa tccaaatgtc atgagaaaat agagaccatg
     7141 aatctgttgc tttgatgtcc cctgcatttt caggtttgac cagaccaatc cattctgttt
     7201 cattcaaata tattccttgt tctggaatca gcaacaagcg ctggtcttct gtctggctag
     7261 ttgcttgttt ttctttttta gagagtacaa caaaatgata ctctcttttc agtatccaat
     7321 tattgccaat actgagttgc cattggcttt ttttctgttg ccactggtct aaaatcgact
     7381 ccatttgttg ttctttcaaa ataattcctg tttttgagaa tgctttgtcg aaaaaggagt
     7441 aaaaaaaata gtatcgttca gcatctgtca tttcttcaat catttctgca gaaaatcgaa
     7501 attgttcctc ccactgttcg acttcctttt cgatcaactg tcccatatat ttttgaatga
     7561 cttggtctgc ccattggatc tgttgcgaaa attgctggaa atgtctcaac gcctgtgtat
     7621 tttcttgttt caattgagga actaccaaat gacgaagccg atttctctgg atatctaaca
     7681 attggtttgt ctgatcctca aagtaaacaa gctgcgattc cgctgcataa gtatataggt
     7741 cttctttgct aaaactcagc aacggacgaa tcagtctgcc cgtagcaaat ggttgtactt
     7801 ctttgattcc agaaaaagta tttaactgtc ccccacgaac gattttcatt aacaccgtct
     7861 cgatttgatc atctccgtga tgagcagtca tcaacgtgtc atattgtcct tcttccatca
     7921 cgcgagtgaa ttcttgataa cgaaagttac gagcttctgt ttctatggcg gatttggctg
     7981 gatcttccca aatacttaca tataaaggga gattcttctc ttcacaatat gagcgaagat
     8041 aggcagcttc ttctgctgat tcttctctta attggtgatt gatgtggacg atacctaaag
     8101 aaaaaccgat ttggcgttgc acttgtaaaa gtaaatggag caaaaccatc gaatcaacac
     8161 cacctgatac cgctgctaaa attctcgatc cttgttgcca gaatccttgt tcattcccgt
     8221 gccgaataaa tgactgctgt aatagcggtg cttttttccc gcctttttca acgttcatcc
     8281 tttccacacc ctttcttcct aaaaaaaaga gagcgggaaa acgtctaaaa cgacaattaa
     8341 cctgccctct gttgatacta tgacccaaat agtcgcacta tcattatttg cggcttttta
     8401 gctgcgacgt ccgccacggc caccgcgctt tccttctgtg tttcgcttca atgaagataa
     8461 gcggtcatcg ctatctttca aaaatgaact catcaatgaa tcgaagtctt ctttttgagc
     8521 tgaaggttga ctgcgagaaa aagatttttt ctgtgctgga cgatttcggt tgtcacgggg
     8581 atctttttgt tgatattttt taggacggct ttcttctcca gattcagcag gttgttcctg
     8641 cgctttccgg atagatagtc cgatttttcc atcatcattt actgaaataa ctttaactgt
     8701 tacttcatct cctacactta aaacatcatg gatgtctttt acatagccat ttgacacttc
     8761 gctaatatga actagacccg tttttccagc acctagatca ataaacgcac caaaatttgt
     8821 gattcctgat acttttcctt gcagttttgc tcctacctcg attgacataa aaaaaatgtt
     8881 cctcctaatt atttcccttt tttatattcc tgcttatttt gcagttgtag aactagttga
     8941 ttgatctgtt tcatttgtcg agctgtctgt atttgattct aatataggat aaactttttc
     9001 accgtctttt gagtaaaaga atttgcttct ggcaagttta gctacatact catcatcttt
     9061 cagcaatgaa acatcttggt gcagctgatc aacgtctgcg ttgacttctt tcatttcagt
     9121 atttgcttcg actctcaatt cgttcaattg atgcatcctt tgcatgtcat ggaaaatctg
     9181 cacacctatt atcgcgaaaa tgaccaaagc accaacaaaa attgcagcca gtctgcgtct
     9241 tcgaaaaatc agttgacgtt gttgttgctg aaattcagca tactttttct ttgcatattc
     9301 cgtatctagc gcagcgattt tattgctttt tttcgtcact tggattcgct ccaatctttt
     9361 tgattgtctt tttcattata ccaatatcgt gaaagcttgt ctaatctatt tctctagtgt
     9421 ttctgtgcga ttttcagaaa taatttcgta cattttttgt gcatcttctt ttttggttga
     9481 ttcatgtaat tccgtaattt tcacttccaa cgttttgttg ccaaactgga ctttcaaaat
     9541 atcgcctact ttgacatcac tggaagattt cgccaattta ccgttgattt gaattcttcc
     9601 tttatcagct acttcttttg ctactgatcg tcttttgatg attcgggaaa tttttaaaaa
     9661 tttatctaat cgcatatctt attcctcact ttttaatttt tttatttaat cgcaggattt
     9721 tcttaccaaa aggcaacatt agccattctc gtactgtaaa cagacgaaga cgaatcactg
     9781 cataaatgaa cacagaagcc ccgatcccaa ctcctatcac gctgacaaaa aaagcagtgg
     9841 aacgatgagt tacaggacca aatactatat tcaatacacc ataatacagc agcagtacta
     9901 ctgtcataca aagaaggctg aacatcaact tccgtccaaa atgccgttct ttccaaaaag
     9961 catttagctc ttttgtttca attcgaacaa aataccaaag cgtcacacct aatcctaaaa
    10021 gggtagacag gcttgcacct gctgttccta ataaaccggt cagaaaagaa gtagtcaatc
    10081 cttttaccaa tagtccccat cctgcgcctt ttaaagaagg gcgaaacgag ttcttgcttt
    10141 gagcaatact ttgataagct tggatgactg cagtgaaagc aatggaaaaa acaaataata
    10201 caagcgctgc atttcccgca taatctttaa acaacgcata attgatataa gggagcagca
    10261 aggctaatcc caaagacgca gctaatgcta aagcggtcgt caatctaaga tagattttgg
    10321 ctgtctgtaa aaactgacga tagatccggt tggtcaaatg acgagtcaac gcaggcagga
    10381 atgtcgcact taatgcagtg gcaatcacta aacctaattg tactaaaggc tgacctcgat
    10441 catagacccc ttttgctatc ttcgcaccgt attctgacag tccgtaaact tccaaagcat
    10501 tttttacaaa gaaagagtcg atcagctgga aaaagataag caatccacta taaatcgaaa
    10561 ccagtccgcc ttctaccaga aaacgccgga tcaagggctt tgacggctgt ttgaacaatg
    10621 gaaaccgtcg gaagcttaac gctcctccat gaatcttttg ttcatagtag tgaaggatcc
    10681 catatgcgca taaaccgcca aaaacagctc cactcattgc tgccgtccct gtttggtaca
    10741 ccgtccatcc aagctttcta aaagcaaacg cactacagac aatcacaaaa acacgaacga
    10801 actgctcaac tacttgagaa acagcagttg gttccatcaa gaatcttcct tggaaattcc
    10861 ctcgataaaa agatagacca ggcatcagca aaaaggtaaa ggaaactact tggatcagcg
    10921 gtttcaattg tatgtctccc atcatccaag caatccagct gctaaatgca aagacaaaca
    10981 accacaaaaa gacacctgtc caaaatacta agggataaag attttgcaaa gcttgctttc
    11041 gctcgaaagg attctttctt tctgcaacgt actttgatat gaactgcgga agaccggata
    11101 aagctaaagt cattgctatc ccataaattg gataaacttg ctgataaaca taaaaacctt
    11161 cgtcgccgac taagttttgg aggggaattc ggtaaagggc acttaatact tttgctatga
    11221 aagaagcaat cgtcaataca aatgctcctt gcatgacgcg ccgcatttct ttatgatcca
    11281 aatcattgct ccttcctacg ctgacagata tttttgctca cgcaacgctt tgacaaactt
    11341 ttggatttcc tgaagccata ctgcttcttc catttggttg gggatcgtca agcgtatcac
    11401 catctgttct ttttcaacgc ctagactggc ttttagtttt gtcgctgtca gtgcttcgaa
    11461 taactgttcc acactatagc gttttgttcc aactttactt agagtaaaga ctatatgcgc
    11521 ctcctgtttc cttatcgttt ctaggagcgc tcgatcgcca tccattttga tctgcccaat
    11581 tgtcaagaga tgtgctactt cttctggata ttctccaaaa cggtcgagca gatcatcttc
    11641 tagttcatct agcatttctt gcgaatcaag ttcacgaatt cgtttataga tctcgatttt
    11701 ctgccgttga tctgccacgt atgtttcagg tagatacgca tcgacaccga ggtcgatctc
    11761 aacagtggtc ttctccactt gactattctt tccttgttta cgagaaacag cttcgcttag
    11821 catttgagaa tacatatcga aaccgactgc atcaataaat ccatgctgct gagcacctaa
    11881 gagattacct gcaccgcgaa tggaaagatc ccgcatcgca atcttgaatc cagatcccag
    11941 ttctgtaaaa tctttgattg cctgaagacg tttttcactg acttcgttaa ggatcttctg
    12001 ctgctcatac ataaagtaag catatgcgac acggctgctt cttcctaccc gccctcgcaa
    12061 ttggtataac gtggataatc ccatataatc agcgttctca acgaacaacg tatttgcgtt
    12121 cgggatatct actcctgttt caatgatggt tgtagtgaca agaacatcat attgaccttc
    12181 aataaattca aaaagcgtat tttctaattg cgcctctgtc atttgcccat gagcataacc
    12241 gatccgtgct tccggaacga gttcttggat ttcttctact ttttgttcga tcgtttctac
    12301 ccgattatat aaatagaata cttgtccacc tcgtcccatt tctcgatgga ttgcttcgcg
    12361 aatagcccca ggattttttt ccataacata cgtttggatc ggataacgat tcgcaggcgg
    12421 tgtttcgatt actgaaagat cccgcacgcc taacatcgac atatgcaaag ttctcggaat
    12481 cggtgttgca gtcagagtca aaacatccac ttgtgcacgt aactgtttca atcgttcctt
    12541 atgttttaca ccaaaacgtt gttcttcgtc aatgatcagt agacccaaat cgctaaattc
    12601 aatatctttt gacaaaattc ggtgggttcc tacaacaata tcaacttgac ctgtacgcag
    12661 ttgttcgatg gtttcttttt gttgctttct tgttctgaaa cgacttaata gcccgatatt
    12721 tacggggaaa ccttcaaatc tttccagcat cgtttcatag tgctgctgtg ccaagatcgt
    12781 tgttggaact aaaaaggcta cttgtttgct ttcctttatc gctttaaagg ccgctcgaag
    12841 cgctacttct gttttcccat aaccaacatc acctacgagt agtcgatcca ttggtttttc
    12901 tttttccata tcccgtttga tctccgctgc acttctcaac tggtcatcag tttcagagta
    12961 ggggaaggca ttttcgaatt ctttttggta ggcgtcatca ggtccaaaag catatccttt
    13021 ttctgactct cttgcggcat ataatttgat tagatcgtca gcgatatcct cgatttttga
    13081 agagactttt cgcttggttt tcgtccattc acttccgcct agcttattga tgcgaggcgc
    13141 tttggcttca gaggcgacat atttttggat cagattcagt tgagtaacag gaataaacag
    13201 tttgtcgtcg ttttgataca aaatagtcat atagtcttgg tgaacgccat ctacttctag
    13261 cgtttccatc ccaatgtatt tcccgatacc atgattggca tggacaacgt aatctcctgc
    13321 ttttaactca ttatagcttt tcaatcgctc tgcgtttgtt actgtttgac gtctcgtttg
    13381 ttttttcgtc gttttttgga aaatttcttt ttctgtgata gctactattt tttcttgagg
    13441 aagttcaaaa ccagcctgca aagctccttc aactaattgt acctgtcctc tgatcaatgc
    13501 atttttttct gtttctacta ctaatatgtc ttcatctcga agcatttgtt ctgctttgcg
    13561 tattctgtcc tttgtcggaa taaagatcac aacagtctgt ttttgcttgc gccaacggtc
    13621 catttctgtt ttcagcaatg gcatttgtcc gaagaactgt tgcatcgtcc gatattgaaa
    13681 attatggatt gcttggaaac gaagatttcc catccctttt tggaagagtg agaaaaaggt
    13741 tgtggtgaac ttttccttct gcacgatttt ttgtatatct gctgaaaatg tctgctcaga
    13801 aaacacccgc aattcgctga ttttttgagt ctgccattct gccgcttccc tttcgatttc
    13861 ccgatttgtt tccatgattc gctgataatc atcaacgact agtaaactat ttgaagggaa
    13921 ataatccaag atcgtcacag attcttggta aagaagatct gagtagaatt ttgcttcttc
    13981 tgtcgggaca cctgcttgcc agcttgaagt cagctgaccg aagtaatctt gcaaaaactc
    14041 gcggtctgct tcttctgtgg tcgcagcaag ccgtttttct agcatttttt gcatttgctc
    14101 tattccatgt tctagatcct ctggtccgta gacttgttca ctcgttgggg aaacccagat
    14161 ttcttccgtt ttttcgattg agcgttgtgt ttctgcttca aaataccgca tagaatctat
    14221 ctctacatca aatagttcta cacgaacagg ataggttgtc gttaacgggt aaatatcgat
    14281 aatgcttcct cgaatactga attctcccgg ttttgcgacc atctcttctc gtacatagcc
    14341 catcaaagtc aattggcgag gaagattttc cacgtctatc tcatcaccaa tatgccaatt
    14401 caattgcgcc tgtagccaag ttttcttatt cggcagtcgt ttgtgcaaag atgcgactgg
    14461 caacaaatag atacctgctt ttttttcttg aagtgcgtta agcgttgcaa ctctctcgcc
    14521 tcgcgcttct ggagaagaaa aggccatttc agcagaaagc acttcatcca ctggaaataa
    14581 atggatctga tcttgcggaa tcacatgttg cagatcttct gctaactgat tcgcataata
    14641 caaatttggc atcagaataa tcatgttttt atttgttttc ttaaacgctc gagcaaatag
    14701 aagtgttttc gctgagcccg ctaatcctgt gattagttgt ctaggcattt tttcttctaa
    14761 attgctgacc cattctttta cttgcggatc ttttccgact aattgaataa tatccattcc
    14821 ttttcctcct tcctcaattg aatcgattca tcgcatccac gaacgaatgc ccttctatga
    14881 gatattcgac tgctttaaca gattgacaca tgctttcttc tatcaaaggc tgattttctt
    14941 tgctgaaagg actaagcaca tgctggacta ctgttttttt cccttctggc ctgccgattc
    15001 ccaccttgat tcgatcaaag acattcgtat tcaaatggga aataatactt ttgataccgt
    15061 tatgcccgcc ggcacttccc ttttgacgga gccggatttt tcccactgcc agatccaaat
    15121 catcgtagat tacgactaat tcctctggat aaatcccaaa ataagtcatt agtgggccga
    15181 ctgcacgacc agattcattc atgaatgttt gtggtttgac taaaaggatc ttttctccat
    15241 tatgaaaaaa ttcggcaact tctgcttcga acggattttt tttgaaagta gcttgatgct
    15301 cgcgtgcaat tttatccacg accataaagc cgatattgtg ttttgtatat tggtatttgg
    15361 tacctgggtt tcctaacccg acgatcattt tcatttttgt tttccaccta attctaaaaa
    15421 gcagcacaaa aggctggact gctaattagc ggtccagtcc atcgagcttt tttctttttt
    15481 atacttgtca atgcatagta taacacaaaa caaggcgttt cggctaaaag agaatcgtta
    15541 ataaatgata aagaaattaa aaatttcttc aaagtttaat gaaataattg atatataaaa
    15601 atagtgaaat aacgcacatg taagctttta catataatac aaccttgtta tctgttatat
    15661 tttatagcca aatagcgtga catggggctt gagaaatgtt agcataagca tgggaaaaaa
    15721 caaatcaatg gaaggattga tactaaatga ctgcagctgc agaaaaaaaa gatcatcaaa
    15781 aagttattct tgttggagac ggcgccgtag gttctagcta tgcctttgct ctagttactc
    15841 aaaatatcgc tcaagaagta ggtattgtgg atatcaatac tgctaaaact gaaggagacg
    15901 caattgactt gtctcacgct ttggcattta cttcacctaa aaaaatctat tctgctactt
    15961 acgcagacgc acatgatgct gacttagttg ttattacagc tggcgcacca caaaaaccag
    16021 gtgaaactcg tttagactta gtaaacaaaa acctaaaaat caaccgcgat gttgtcacac
    16081 aaatcgttga atcaggattt aacggtatct ttttagttgc cgctaaccca gtagatattt
    16141 tgacttactc aacttggaaa ttctcaggtt tccctaaaga acgcgtaatc ggttcaggta
    16201 cctctcttga ctcagctcgt ttccgtcaag cacttgcgga attagttgac gttgatgcac
    16261 gtaacgtcca tgcttacatc ttaggtgaac acggagattc agaattccca gtttggtcac
    16321 atgcaaatgt tgccggcttg caaatctatg aatgggtaaa aaacaaccca gaaatcgatg
    16381 aagaagctat ggttaaccta ttctttggcg tacgtgacgc tgcttacaca attatcgaga
    16441 aaaaaggcgc tactttctat ggtatcgcag tagcattagc acgtatcact cgtgccatct
    16501 tagatgatga aaatgctgtt cttcctttat cagtattcat gaatggcgaa tatggattga
    16561 acgacatcta cattggtgca cctgctgtta tcaaccgtca aggtatccaa aaagtaatcg
    16621 aaattccttt aagtgacagc gagcaagacc gtatggctgc ttctgctaag caattaaaag
    16681 aaattctaga tgaagctttt gctaaactag acgctgaata atctttgaac atgacggaaa
    16741 acatctattc ggtgttttcc gtttttttat tttatcaccc ttatggtttc taaatttttt
    16801 cataaagtag agataacctt cgtcttttcc tctaaattat gctatcatga gaccgttcca
    16861 ccctaaactt ttacttaagg agttgtcgat atgacaagat cttcgcatcg aaaaaaatcg
    16921 aaacatgttg ctttgctttc agttcttggt gttctcttag tgctgatcag cttttatacc
    16981 tatcgcagta catactacac aaagcatttt ttgccgaata cagaaataaa tggaataaat
    17041 gtcagcaatc taacagtcga aaaagcaaat gaaaaattaa aagaagctta ttctgataaa
    17101 aaactggcta ttaaagaaga tggaaaagtc tggcaggaag taccaaaatc cgagctcggc
    17161 tacaaagatg atttcacttc ggagctttct ccgatcctaa atgaacaaaa cggatggact
    17221 tggggaatga cttatgtctc agcggcagaa aaacaagaaa tagatcctgt cagtcaaaac
    17281 caccaaaaac tagacactac cgttcagaca ttgacaacta agctgactga tttgaacaaa
    17341 gaccggacac ctactactga tgcaacgatc gaaaaagcag gtgactcttt cgttatcaag
    17401 cctgaagtca atggaaatac gatcgacgtc gatgctgcgg tcaaacaatt aaaaagtgcg
    17461 gtaaactctg gtaaagatac aattgaattg actgaattca aagaaaaacc aaaagtaaca
    17521 tctgaagaca gctcactgaa agaacaactc gcatccatga atgctatcgc aaatgtaaaa
    17581 gctacttaca gtataaacgg tgagactttc cagatcccat caagtgatat tatgagttgg
    17641 ctgacctaca atgatggaaa agtcgattta gatacagaac aagtacgtca atatgtaaca
    17701 gatttaggca caaagtataa cacaagtacg aatgacacaa aatttaaaag tacaaaaaga
    17761 ggagaagtta cggtcccagt tggcacttac agttggacga tccaaacaga cagtgagaca
    17821 gaagcattga aaaaagcgat tctggcaggc caagatttta ctcgttcacc cattgtgcaa
    17881 ggtggcacaa ccgctgatca tccattgatc gaagatacgt atatcgaagt tgatctggag
    17941 aaccagcata tgtggtatta caaagacgga aaagtggccc ttgaaacaga tatcgtttcc
    18001 ggaaagccaa ctacacctac acctgctgga gtcttctatg tttggaataa agaagaagat
    18061 gcaactttaa aaggaacaaa tgacgatgga acaccttacg agagtccggt aaactactgg
    18121 atgccgattg actggacagg tgttggtatc cacgattcag actggcaacc tgaatacggt
    18181 ggagacttat ggaaaacccg cggttcacac ggctgcatca acaccccacc aagtgtaatg
    18241 aaggaattat tcgggatggt cgaaaaagga acgcctgtat tggtcttcta acaaaaataa
    18301 tatataaaaa gaaagcaccc gtacgattgg tacaggtgct ttctttttat tatctaacaa
    18361 tgtgctactt acatttcagc agcagtaaag acttctgaaa catcatcatc gtcttctagc
    18421 ttatctacta gacgttccaa ttgctctttt tgttcctcat ttaaatcaat cgtcgtttgt
    18481 ggaatcatcg tcaattctgc ttgcgccaaa gtgaactctt tttccaactc atctcgtaca
    18541 gcagcaaaat cttctggtgc agtataaatc tcgaatactt caggagaagt ttgcagatct
    18601 tctgcccccg cctctaatac atcctcaaac atcgtctctt catcaacagt caacccatcg
    18661 cgttcaatag cgatatatcc tttgcggtca aacaagtaac tgactgaacc cgtttctccc
    18721 agtgatccac cgtttcgagt aaaagctact cggacatttg tcgctgtccg attacggtta
    18781 tctgtcaatg catggactaa gattcctact ccacccggac catatccttc atacgtgatt
    18841 tcatcgtaat tcgtttcatc tacggcactc gtagcctttt taatcgcccg ttccacattg
    18901 tcgttaggca tatttgcagc ttttgctttg tccacaacaa gccgcaaagc tggattcata
    18961 gatggatcag gaccgcctgc tttagctgcc atataaattt cacgagaaag tttctgaaag
    19021 actttccctc gttttgcatc ttgggcattt tttcttcctt ggatattatg ccatttacta
    19081 tgtcctgaca tgatttttcc tcccttgttc ttttgagaat acacttctat tctagtacta
    19141 tttcacaaaa aaacaaagcc acagccaatc tataaacgct tcttgaatgc cgcaaaaagc
    19201 acacataata tcacagcagt cagagcaccg atcgaatcca acatgacatc ttggaacata
    19261 ggtgttcgtc caccggtcat catctgatgg aattcgtcca aacctgcgta ccctgttgct
    19321 gaaagccaag caaggatcgc tgtcagccac caaattttta gcttggggaa aacacctaaa
    19381 aacaagctgc ctcccaaaat aaaataggta ccgaaatgtg cgcccttcct taaaaagaac
    19441 tctaaaaatt tggcgtagcc cagatggtcg atactcacca tacttccacc ataattaaaa
    19501 cgtatacccg ctaatgtgtc tttaaatggc tgattaggca gccagctttc taatcgcgaa
    19561 acttgtgatt gctgtccgta agtttgagaa gaactgtaaa ataagattat aacgactatc
    19621 agtgcgatta ctaaataaat atttccgttt ttcatttgtt tttttgaaga attcataagt
    19681 cacctctgta ttttatctta gacttttttt gaagaaacaa caatcatttt catagagact
    19741 tcttccataa aaaagtgcta tacttaattt tgtattacaa tatgaaggga gttttttcat
    19801 gagttattca ttaaattgga atctagattc tattttttcc ggaggcagtc attctgatgc
    19861 tttgaaccaa cggatgaagc aattggaaga ccaaatgaac gagtattatc accgcgtaac
    19921 aaaatggtca cctagttctg acaatgcaga gcagttaaac gctattcttc aattgcaaga
    19981 aacgattacg aatggtttta cccaatgcag cagctatatt actgcattgc tttctgccaa
    20041 tgtcaatgat tcagatgcaa aggtcttatc aggcaagctt tacgcaatgc tgcctcgtct
    20101 gcaatcagcc gaaactgtat tgtcaaagaa atttgcagaa atatctgaca atgattggaa
    20161 tcagatgctt tctcaatctt cgtttgaaac aattgctttt cgtttaaacg agattcgtcg
    20221 tgatggctca caattattat cagaagctga agaaaacatt ataaatacgc tttctttaga
    20281 tggtctaaat gcttggagca gtcattatga tacgattgta gccagcattt cgattccctt
    20341 cgaacaagat ggacaagtag tcgaattatc tgctggacaa gccttcaata agatgatggg
    20401 cgatccagat ccaaaagtca gagaaacact tttcgcagca tgggaagaag cctggaaaga
    20461 aaaggcaccc ctcttcacgg atactttgaa tcatttagat ggttttagac tttctgacta
    20521 tgaacttcat ggtgtcacag attttctaca aaaaccatta gagtacaatc ggttgaagaa
    20581 agaaacattg tctgtcatgt gggatacaat ccagaaaaac aaacaacccc ttgttaatta
    20641 cttgactaga aaagctaatc ttttcggtaa agaaaaaatg gaatggcaag atcaagatgc
    20701 acctattatt ttaggcgatt tgaaagaaaa aacctttagt tttgacgaag cagcagcatt
    20761 tattatcgaa aactttaaca aattcagtcc aaaaatggct aaatttgccc aatctgcttt
    20821 tgaaaagagc tggatcgaag cagaagatcg tcctgggaaa cgtcctggtg gttattgtac
    20881 tgagttacca gaaacaaaag aatcaaggat ctttatgacc tacagtaatt ctgttaatga
    20941 ggttgcgaca cttgctcatg aactaggaca tgctttccat agcagcacga tgtgggattt
    21001 accttcttta aatcgcgaat atgccatgaa tgtcgcagaa acagcaagta cattcgcaga
    21061 actgatcgta gccgatgcta cattaaaagt cgcaaaaaca aaagaagaaa aaatcaattt
    21121 gctagataca aaactgcaaa atgctttagc tatgttcatg aatatccatt cccgattcat
    21181 ttttgaaaat cgattctatg aagcacggca agaaggatta gtctcagaag ataagatcac
    21241 agagatgatg gttgaggcgc aaaaagaagg ctatcaagga gctttagcta cttaccatcc
    21301 atatttctgg gctgcaaaat tgcatttctt tattgatgac gtaccgtttt ataacttccc
    21361 atacacattt ggctacctct ttagtttggg catctatgct tacgccaacc aaaagggagc
    21421 aaattttgaa gaagaatata tccatttact acgcgatact gcctcaatga cgacggaaga
    21481 tcttgcgaag aaacatttga atgtcgatct tacccaacca gatttttggc aagcaggtat
    21541 cgacatggtg actgaagata tccaaacgtt catggaattg acagaagaat ttatctgatt
    21601 tctattttat cacaataaaa aaagagttag tccagaatgg gctaactctt tttgattaat
    21661 cattcttaca tgctgacagc aaagtcaggg gcaaaccatt gaactgaacc aacttttacg
    21721 ctttcgcctg gttgaggagc atggatatat tgtcctccgc ctaaagcaat cgctacgtgg
    21781 taagttccgc cttgtgaccc ccagaataac aagtctccag cttttgcttg agaaactgaa
    21841 atttttgttc cagctgattc ttgaggaact gtccaaccac cgatgtcacg accagttact
    21901 tgcatgtaaa catagcgtgt gaaccctgag cagtcaaagc cacttggatc tttaccgccc
    21961 caaacatatg gagtaccaat atatttgtaa gcttctgcta cgattgctgc accattcaca
    22021 cttccagaag gagctggagc aggtgttaca ggttttggtt gttcaggtgt tggtgttggc
    22081 gttggagccg gagtactact tcctgtgccg tttcctgtat caacactttg atctgttgat
    22141 ggtgttgtag gcgcaggtgt tgttgattct tctgttgttg aagattcagg cactgttgtt
    22201 gattcttctg ttgctgaaga ttcaggcact gttgttgatt cttctgttgc tgaagattca
    22261 ggcgctgttg ttgattcttc tgttgctgaa gattcaggcg ctgttgattc ttctgttgaa
    22321 gattcaggtg ttgttgattc ttctgttgct gaagattgtg tagctgatga tgattcttca
    22381 gtcattgaag attgtgtagc tgatgattct tctgttgctg agctttgtgc agtagatgaa
    22441 gcttgagtag cttgtgcttc agcctctgct tgttcgcgtg cttctttttc agctttttct
    22501 tgtgcagctt gttgacgagc ttgttctgct agacgttgtt gttcacgaat acgagcttgc
    22561 tctgcttcag cttctgcttt ttgacggttc aagtcagctt tcttgtcttc agcagttgct
    22621 tgttcagcag ctaatgaagt tttcagtacg ttcaaatcag cttgtttaga taaaagatcg
    22681 cctttttgag attccaaagc agcttggttt tcagctaatt cttttagttt agcatcgttt
    22741 tcagcttttt tgtcttctac agctttttta tcttgttttt gttgttccat caagtcgttg
    22801 tttgctttta ccatcgttgt cattgcttga acgcgtccaa tagcatctgc taatgaatca
    22861 gcattcaata cagcatcgat gtagtttgag cttgtgttgc ttacttgtgc ttcgcgtgct
    22921 tgtttttgga ttgtatcttc acgtttttca atacgttctt gtaaatctgc aatgtctttt
    22981 actaattgtg cagattcttg acgcaatgta tcttgttttg ctaataggtc ttgtgcttgt
    23041 gtgttgattt cagaaacttg gctttctaag gcatcgattt gtgattgtgc atctgcttgt
    23101 tgatttttca agtctgcaat cttttgatct tgctgttgta tctgagaatc aaaatcgtcc
    23161 gccgcggcag cgatcggtga tgctacggca gtcaaggtca ttgaacatac cattactgct
    23221 gatattaaac tctttttcac tcttcattcc tccgactggc ttaatttaat aaatatctaa
    23281 atatatttaa gtctttctta acgatataaa aattgtacca tagcagtgtg tcaacgatat
    23341 aatagttatg ttacaaaaat gtttcaaaac aacttttaaa aatgacaaaa ctgttcgttt
    23401 cagaaaatga tcatgaaaaa gccgcgttaa gtctagcatt tcttaagata acaacgattc
    23461 tttttcgctt tcgacctaaa aataaaaaaa gaaattattc atcactgaat aatttcttaa
    23521 agggaaaaat gaataataca aatataatca tgttcaacag cagtgtaggt cctaaaaacc
    23581 ttgtaataaa atacgtgtta tttactactg ctaatttaaa aatcaactgg accaccatcg
    23641 taaacaattc ataacccgtg acaaagatga tcatactgaa aaattcagta aagatgttga
    23701 catggataac gtctttcatt acatacatca accatacaat taaagggaga gctactgcat
    23761 agataccgat aacgccaata tagtaagcgt catagatagc cccgagaaca atcgtggtaa
    23821 tcagtaaata acgtttttca aacgccatac tgcaacataa taatgccaat atcagaaagt
    23881 gggcatttga catataggtg cctttcgacc actcccctag cattcttgtt aaatgaccat
    23941 ctatcaacat caaaaagaac aaaacgattg gcagatagta cttcattgtt tctttcttca
    24001 acatggacta atcctccgct agccgttgga caatcgtcac aactgacacg tcatacattt
    24061 ctgcataagg tttcacataa acttcccgat ccagcccata actatctggt ttcgttttaa
    24121 taaccgtacc gatcggcaag ttagctggag aattccctcc aagaccggat gtctggacaa
    24181 catccccttc tttgatatcc gtatcaccag ttaattgggt caccactaag gcatggagct
    24241 tttcatcata gtttttaagc aaaccaaacg cttcgccatt agccgaagat acccgtactg
    24301 gaaaatgatt ggagctttca ttagaggatg acagtaattc gattttagac gaagccgtat
    24361 tgacctcgat cactcggcca atcaatcctt tttgcgacat gactgccata tttgcttcga
    24421 taccgtcttt agaacccttg tctacgatca gcatgtcctg ccaactgtca ggcgaacgag
    24481 taatgacatt tgccgttact ttttcgtaac tagtcagcgt ctgattcaac tcaagttctt
    24541 ttttcaacgc ttcgatttct ctctcgtaat tcttgttttg ctgtgaaacg tcatcatagc
    24601 tatcgatttt ttcttttagc cgctcatttt cggcataagt tgaaaaaaga ttatggacag
    24661 aatctactcc atttcgtacc caccgtactg gggcagagat tgttttatca accattgcaa
    24721 cactgtcatt aacgatggat tggaagaaat tgggctttcc ttcattcgct cgctgcgcag
    24781 cggtcacact tagtatcgtc accacgatga taacaataac caaggtaata ataatatttt
    24841 tattaggatt gaacttcttc acaaagacac ctcgaattaa ttagactctt gtgttcaatt
    24901 ttatcactaa atgccgtgaa acaaaaggta agttgctcct cttaagcttt tttttagcaa
    24961 ataatagatt ctgtcatttt tagcctgaaa gacaaatttt tttatttgtt tatggatcaa
    25021 tctttgcttt gaataactgc aatcatacca tctgaaaaag aaaattctgc ggtatctgaa
    25081 agaaattcgt tacttgcata agatgtcgga tattctactt ctttattttc caatacatac
    25141 ttgctgcctt ttaatgtaag attcgagacg ggagtcaagc agcaataagc taaatacttc
    25201 atatctggta tctgtcttac tatatgctct ccaggcaaat aataagacaa ataattttga
    25261 caatctctga taataagctg atgggcaaag ggtttgaagc gaggttccat acctaaccag
    25321 agattggcta aaagatgatc caatcttccg cccgtagctc caatcaaagt gacttccgct
    25381 tgcgggtaac gttcaaatgt ttttaagata cctaactgtg tatctgtatc gtctttttct
    25441 gcaggggaac gggtatactc tttggctttt gcaaatactt ccttctgctc ttcgttcgac
    25501 aatgaatcaa aatcgcccac tgccagatct actgggtagc ctgcttgaag caggtacagc
    25561 gcaccacggt ctatcccgac ataggcatcg tatttggaca gcagagactg cggccagttt
    25621 tgcggattac ctccagcagc taataaaatt ttcatttagt ctaatgcctc ttttaatcgt
    25681 tcgatttgtc cgactggatt ttcggctcca tagatatatg atcctgcaac gaagacatcc
    25741 gcccctgcat ctttacagat ttttgctgtt tctggaacga ttccgccatc tacttcgatt
    25801 gcataagtcc aattgttctc tctacgtaga tcagcgagtt ccgtaatttt ttctactgtt
    25861 tcttcaataa agctttgtcc gccgaaccca ggattgacag tcatgactag tacttgatca
    25921 gccaaaggca aaacatgttt gatcatggag actggtgttc ctggattgat aactactcca
    25981 gctttaactc ctaagctttt tgtcatttga agtgcccgat gaatatgagg agttgcttcg
    26041 acgtggacag taatgatatc tgctccagct tttgcaaatg ctggaatgta gttttctgga
    26101 tcaacgatca tcagatggac gtctaacggt aatttagtaa caggacggat tgcctgaaca
    26161 atatttggcc ctaatgtgat atttgggaca aattggccat ccattacatc tacgtggatg
    26221 taatctgcgc ctcctttttc cactaactca atgtctcttt gtaaattggc aaaatctgca
    26281 ctcaaaatgg atggtgctat cttcattctt gtttcctcct attttcgttt accttctttt
    26341 tttgcataca ttggttttct tttttcgatt tcttgtaaga attgcaaata attgtcgtaa
    26401 cgtgtctgtg cgataccacc tgtttctact ctatgtttta cttcgcagcc aggttcttta
    26461 gcatgcatgc actctctaaa tttgcaatgg acagaagctt ctacaaattc aggaaattgt
    26521 ctcggcagtt ctcctgcttc aattgtcaaa aagtcaatcg agctaaatcc tggtgtatct
    26581 gctactaacc cgccatagat aggaatcagt tccacatgac gtgttgtatg ccgtcctctt
    26641 ccaagtgcat cagaaatctc tcctgttgct aaattcagtt ccggtgatat ttgattcagt
    26701 agcgtcgatt ttcctgctcc agactgaccc ataaagaccg atagccgttc tgggaagtaa
    26761 cggatcagtt ctgtcgtatc acccgtatga ttgggtacaa tcaccggata gcctatttta
    26821 gtataggttt gcttgatctc ttcgattttt tctgggtcgt ctgacaagtc ggtctttgtc
    26881 aaaaaaataa tcggttcgat cgactcgtat tccaaggtaa ctagaaagcg gtcaagtaga
    26941 ttataagaaa atgcaggctc tacgatactt gtgacaatga ttccaagatc aacatttgtg
    27001 actggtgggc gaactaattg attttttctc ggcaagattt ccagaagata gccgtctgtt
    27061 tgattttcac tctcaaagat cacctgatct ccgacaagcg gcgtgatttt ccgattccgg
    27121 aaatttcctc ttcctcttgt ttgataggtc tctccgtttg cgtatacata gtaaaaaccg
    27181 ctgattgctt ttctgatttg tcctttgata agtgccacct ccgtttttgt ttattttacc
    27241 atacgaagag gaaagtaggt gttattccat gcaaacttct caaagtatat ggcttgaaaa
    27301 ttgatcaaaa gagatagaaa cacaaaaaag agaatgcaac aaatcaatgt cgcattccct
    27361 tctgatatat tttattcagc acttattttg aactttctga ggtgctagct gatgaacttg
    27421 tggagctgga agattcttct tttgaagagt tgcttgtgct actggagcta cttgagctgc
    27481 tagaactgtc tgaagagtct ttttcagaac tagaagacgc tggatctggt cctttagagt
    27541 aaattacgtt cacaaccatt cctttggtaa ttgtcgttcc tgcccctggt actgtacgaa
    27601 tcactttatc tttatccacc gtgtttgaat attcggaagt ctcatgcccg atatattctg
    27661 caccgacact agctaaataa ctttgtgctt cgctttttgt atagccggag atatcattca
    27721 atttaggctc tgttccttgg cttacgacaa aattgatgta agtttcttct gctacaactt
    27781 cacccgaggc tggatcctga ctgatgatcg aacctgatgg tacagtgtcg ctatagtcat
    27841 aagtagcact aatattattg atattgaatc cttgtgtaac aagccaatta cgaacagttt
    27901 cgtagttttc tcctacatga ctactcaaag tcactgtttc tggtcctttg ctgactgtga
    27961 aagtaatcgt gtctgtttta ggatcgactt ctgtatcttc tgatggagat tgcgaaatga
    28021 tcattccgct ttctacctct gaactgaatt cctcttcttt ttgaatcaag tcagcagaaa
    28081 accctaattc tttcaaactt gcttcggcat cttcataact tttaccactg taatcatcta
    28141 atttgatttt tttcgtgccg ctactaatat acagagtgac ttcgcgtttt tgcttgactg
    28201 tcgttcccgc tgccgggtct gtcttcacta cattaccttc ttcgattttg tcatctgcaa
    28261 tttcttctgt ttttgttgct acttctaatt tcgcttttgc gagtgtttct ctagcagaag
    28321 cttcagaaag atcagaaaca tcaggaacaa caacttctcc tcgcccgcca gaagcaaaga
    28381 atacagctgt tccgattcct aaaacagcaa gaatagctaa taggatcagc caccattttt
    28441 tctgtccttt ctttttagga tcaggcagaa cttcttcctc ctctggcaag gtttcgtttt
    28501 ctggcttgtc ttttggcaga ggcatagatt tgaatgaatc aggcattggt gcatcttccg
    28561 taaggggtgt gataactttt gtttcattat ccatcacatg aggctgccat ttttcttcgt
    28621 ttgcacgagc tggtgataat actgtagaaa gatcatcaga catttcctcg gctgacttat
    28681 aacggtctgc aggttcttta gccgttgccc gtaaaatcac gttttccagt gcttgtggca
    28741 catttggatc aagtgctttt atagatggaa gatcatcttg aaaatgtttt aaagcaattg
    28801 ttacagcaga ttcaccatca aacggtacgc tacccgtcaa catctcataa aggatgatcc
    28861 ctaaagcata aatatctgac tgcttcgttg ccatacttcc tctggcctgc tcaggggaca
    28921 gataatgaac agatcccagc atcgtattcg tctgcgtgat cgatgtttca gataaagcga
    28981 tagcaatccc gaaatccgtg atttttacaa caccttcatt atcgatcagt acgttttggg
    29041 gtttcaaatc tcggtggatg atttgatggt tatgagctaa agaaatagca gaaaggatct
    29101 gctgcataat atttactgct gtttcataag gaacaggata atgtgtttgg atatatcgtt
    29161 tcaagtccat tcctttgacg tattccatca ccagatactg catgttgtct tcttcaccaa
    29221 catcgtaaac actaacaatg tttggatgaa cgagttctgt tgctgctaaa gcttctctct
    29281 gaaatcgtcg aatcgcagtc tggtcatttt gaaagtcaaa tcgtaagact ttaactgcta
    29341 catcacgatc caagattaaa tcgtgcgcca aaaatacatt tgccatacca ccgctaccga
    29401 tatttccagt gatttgataa cggccattta attttttgcc caactcgatc atacactgtc
    29461 ctccttatat tcgataagaa gaacggtgat attatccgct ccgcctgctt cattggcacg
    29521 atcaatcagc tcagttactt tatgagacaa tgggccttct tgattgatga tcgttcctat
    29581 ttcttcttca gacagcatgt tcgtcaagcc atctgaacat aacagcagtc gatcttttag
    29641 ttgccaaaga tgagtagaaa catctacttc gactgttcca ggcatgccga cagaacgtgt
    29701 taaaatattt ttccttggat ggttcactgc catttcttcg ctgatttctc ctgatttgac
    29761 tagttcattg actaaagaat gatcctccgt caattgcatg attttatctt cacgaatcaa
    29821 ataagctctg ctatccccaa cattggcaat cgtgaaccag tcatctgaca gagcggccgc
    29881 tacgattgtt gttcccatac cgttatattc cggctgttct tgtccacgct gataaatcag
    29941 catattttct tcttgaatcg attgaatgaa ccattgggcg attttttcat cgtcaacagc
    30001 ttcttgtttt tcccaagctt cgcctagatt cgttaccgcc atctgactgg caatgtctcc
    30061 ggcacgatga ccacccatcc cgtctgctaa tacagcaagc ttgagacctg aacggctggt
    30121 aaatacactg gcatagtctt gatttgtgtt acgtcgtctt cctacatctg attgatattc
    30181 aatctgcatt ttttcacctc attacttttt gcgcaaacaa caaatgaaaa atccatctgt
    30241 gtaaaactga tgcggataca aagtcaacat tttctcttcg attgatgatt gtagcatagg
    30301 attggtcaaa acatcaatcc tctcaaaatc agggtgtctt tccaagaaag cagaaacaac
    30361 gtcttggttt tcttctttta agatcgtaca agtgctataa gtcagaatac cggaagactt
    30421 taaagttggt gcgcagcttt ctaaaatttc caattggatt tttggtaaat tcgctaattc
    30481 atccggctgt tttttataac gaatatctgg ttttcgccga agcagcccaa gacctgaaca
    30541 aggcgcgtct actaaaatcc gatcaaactg ctctgcttcg aactgtttac tgacttctct
    30601 agcatccatc ttttgagcgt agacagcaga agagacacct agacgtgctg cattatcttc
    30661 aatgagtttg actttgtgtt cgtgtacatc taaagcgacc acttctccac cgcatgacgg
    30721 atctaaaaaa gaagcaatat gcgtcgtctt acctccgggt gctgcacagg catctaagac
    30781 atgatgttca ggctcgattt gcatagacgg cgctacaagc atcgaacttt catcttggat
    30841 cgtcatgacg ccatcgtgga acaatgagct agaagctaaa tgcccttttt tcgctactat
    30901 accgtatgga ctgacttggc ttttttcagc tgtgatctct tcttcttgca aaacagtgat
    30961 ggcctgatct ctggaaagtc ggcgtgtatc tactcgggca ctagcatggc taggctgata
    31021 tagcgataaa ccgagctttt cagtttcttc gtatccgatt tgatccacca gtcgtttcgt
    31081 catccataga ggcaggctga ttttgacaga aagtctttcg ataggatcag caatgccttg
    31141 cagatctggt gctccttgac gctgataatt cctcaagaca ccatttacaa atttccctgt
    31201 cccaggattt ccttttactt ttgcgatttc gaccgcctcg tttaaaatag catgtgcagg
    31261 gactttatct aaaaattcta attggtatac agaaagataa agaagcgtct tgacccagtc
    31321 atccactttt tttgctttag cgatcaatgg tgcaacgtaa aattccaata gtcgctgatg
    31381 gctaatcgta ccatagatca attctgtaaa taaacccaca tctttttgat ttagctcgct
    31441 ttgtttgatc atctcattca acaaaagatt cgagtaggcg ccacccttgt tcactcgctc
    31501 taatgtcagt aatgccatat atcgtactga ttttttcatt tttttaggga tttttttcat
    31561 tatttcacct gctgaccaat ctgaacttgc tgaccgcttc cgttaaggaa atcatgtacg
    31621 gcctgttttc ctttaccagc tggctgtaat tcattgatgg ctaagacggt ctgtttaccg
    31681 caagcaatcc atagattttt tttgtctttc cggatgatcg taccaggtgc tttgtctgta
    31741 gtttctgcca atacttcaac cgataataat ttccagcgta tgccctcata ggtcgtgaat
    31801 gcaattggcc aaggacgcat tccgcgtact tggttgtcaa tttcttctgc agttttatgc
    31861 caatcgattg cttcttgttc ccgtgtgatg tttggcgaaa aagttgcttc tgactcgtct
    31921 tgaggtactg gtttttgtcc atccaaaata ttgggcaatg tttctagcaa tagctttctt
    31981 cctaaaaggc taagcttttc aaacatcgtc cctacatcat cttgtttagt gattggtatg
    32041 ctttcttgcg catagattcc gcctgcatcc atttttttga tcatttccat gatcgttaca
    32101 ccagtttctt tctccccatt catgatggca taatgaacag gcgcacctcc ccgatattta
    32161 ggaagtaaag aagcatggac attgattgcc cctaattttg gtacttgcaa taacttttca
    32221 ggcaagaatt ggccaaatgc cgcagtgacg atcacatcag gcaccaattc aatgatttct
    32281 tccatttctg gcgaaccgga gattttctct ggctgcagca cacggatacc gtgcttcaga
    32341 gccgcttctt ttaccggtgt cggcgtaatt actcgtttcc gcccaactgg acggtcgggc
    32401 tgtgttacca ctgcctggat ctcgtaacct gattctatca gcccttcaag aatcggcaca
    32461 gaaaaagcag gtgtgcccat aaatactagc ttagtcatca agatgttcct ccatatattc
    32521 ttcaagttct tcttccggga tctgctgtat cattttctca atgaacaaga taccgtctaa
    32581 gtgatcgatt tcatgctgga aggcacgggc taaatagcca aaagccgtca cttctatctc
    32641 ttctccgtct cgatcataat aacgcacggt cacttcatct gctcgcttga ccgttccata
    32701 gacatgcgga atactgagac aaccttctac gtcaaggctt tcaccttttg cttcgatgat
    32761 ttctgggtta atcagttcaa atttctcgcc ttcatctact tcgatcacag caattctctt
    32821 gttttgtcct acttgaggag cagcgatccc tattccgtca ttcgcaatca ttgtctcata
    32881 taaattgtct aataaagcga ttgtctcgtc cgtgattaca tcgattggct gagcagttct
    32941 ttttaattta tcattagggt ggatcaatat aggatagcgc ataatttggc cctttcttaa
    33001 ataaagttta atggttcgtt gtcaattgcc acaaaaagac cttgtcgctg ttctttctgg
    33061 cttccattca aaatttcatc caaaacatga ggaagattcg gttcatgttt atatttgatg
    33121 attagttgat aataatatcg gtttttcact ctcaaaatca tgctgggcgt tggccctaat
    33181 agcaagcttt gagggcttaa cacttctttt agctgattgg caatctgaaa gattttcttt
    33241 gccgctactt gttcttcagg atggctggcg gttattttca cagtaaagta ataaggagga
    33301 tagcctccac gatgccgtac atgcatttcc tgctgataaa actgctcata attttgtttt
    33361 ttagctaatt ctatggcgta atgttgagga ttgaatgttt ggatcacgac ttcgcctgct
    33421 ttttccgctc gccctgctcg tcctgaaact tgggtaagca attggaatgt atgctcacta
    33481 gaacgaaaat ccggtaaatt cagggaggta tcagcattca acaccccaac taatgtcact
    33541 tctggaaagt ccaaaccttt agcaatcatt tgtgtcccta ataatatatc tgcttctttt
    33601 gcaccgaatt tttgtaaaat ctgttcgtgt gccccttttc ttcgagtggt atctacatcc
    33661 atacgcaaaa tcctagcttg cggataaagt tctcggagtt cctcttctac tttttgagta
    33721 cctgttccat agtagcggat tttattgccg ccacaattag gacagcgatt gggaataggt
    33781 tcttcatgtc cgcaataatg gcagcgcatt gaacgtgtat ccatatgcag tgtaagagag
    33841 atatcgcaat taggacatgg aagaacaaat ccacagtccc tacacatcac aaaagacgaa
    33901 tatcctcgac gattgagcag taggacagtt tgttcttttt tgtctaatcg attttgtatt
    33961 ttttcctgca aattagcaga aaaagtagag gtccgatgat tctgaaactc ttcacgcata
    34021 tctacgatct caatagctgg aagctgtgca gctgctttgg ctcggtggtt taactgcaat
    34081 aactgataaa cgcctttttg agctcgtgct cttgattcta aagagggcgt cgcgcttcct
    34141 agaactattg ggcaatgatg atatttactg cgccaaattg ctagatctct cgcatgataa
    34201 cgcggtgtct catcttgttt gtaacttgat tcatgttctt catcgataat gatcagcccg
    34261 atatttttca gcggggcaaa aatagcagat cgtgcgccta ctactacttg cgcttcttcc
    34321 cgctcaatct tgcgccattc atcatatttt tcaccttggg aaagtccgct atgtaagacc
    34381 gcaactgatt ctccgaagcg tcctttgaat cgctcgacca tttgcggagt caatgcgatt
    34441 tcaggcacta acataatagc cgttttattt tctgacaaaa catcagcgat tgcctgaaga
    34501 tatacttctg ttttcccgct gccagtgatt ccctccagca aaaagacctg atctttttgc
    34561 tgctgacctg ctgtgatgat ttgttcgaca gcattttttt gttctgcatt cagttccaat
    34621 gccgtcgttt ggtcaaatac tcggtcttta taagggtcgc gataacgttc tgattctata
    34681 aactccagcc agcccttttc ttttccttga ttcaagacag cagtactgat tcctttattt
    34741 ttgaaataag caattggttc ttcttggctc agttcagata aacacaaaag aagttctttt
    34801 tgtttcttgg cattttgccg taattttgcc cattcttctt cgatttgctt ttcagttaac
    34861 aaagaacgga ccaaacgaat cgtttttact ttatttcgtg tatggacttc atatttgata
    34921 tctactaatt gctcttggcg ccagcgaatc aattgagaaa ggctgccttc ttcttctgct
    34981 tccttccagg aaatcacttc tcgctgatca aacaatacct gaacttctgg tgtgtctgcc
    35041 aaaggataga tcaatttatc atattctgct ttcatcacac tcggaagcat cgtttgtaga
    35101 caagtgattt tgaatgcgta agtaattttt ttcatataat cagctaatga aagtaattct
    35161 tcattgacca ccggagcaag gtctagcaaa cgaataactg ccttcaaaga tggattagct
    35221 gattcttctg atttttggat agccataaca aatccttgga catgacgatt gccattacca
    35281 aaagggactt ctactcgcat cccgacttgc aaagctgttt ccatttcaga gggaaccaaa
    35341 taagtgaatg gctgatcggt ctgcatagta ggtacgtcca caatgacttc agctgttaat
    35401 gtcatggttc gtttcctcct ttttttgtct tttcttatca agcgacaaaa agttccttgc
    35461 ctattttact agagatcgat ggatttgtct tatcttctgc caaatcctaa caaaaaatta
    35521 acagcagata agaaaaaaaa gaactgtgtc aaaaagttca gacacagcct tttctaccag
    35581 acaataagtg gcgaatgttt gaaaaggaaa cagctgggtt tgcttttctt tttagatgtt
    35641 cgctctattt ttctttatta cattttttgc tcttcacgga tacgtgattc caattcgtgt
    35701 tgttcacgct ctttttgtgc ttgacgttcc tcttcttcca tcttcaaacg ttcacgtttt
    35761 aattcaggat gtggatcatt gactacattt cctgcatcga tttcttctaa agcttgaccg
    35821 acgcttttta ctgaatcaaa agaatctaga gtaggctgtg cacttgcatc caattcatgc
    35881 gcgcgtttac ttgctaaaat cactagagaa tattttgaat ttacacgatc taatagtgag
    35941 tcaattgaag gttttaacat cataagacta catctccttt aacattttaa tatatttacc
    36001 gattacgcga tctactcgaa aatgttcact ggcaataatg tttttgattc gttcaactgc
    36061 tagcggcact tcatcattta caacagcata gtcgtaaaga gccatcattt cgatttcttc
    36121 ttttgcaact ttcattcgtt cttcgattac ttcatctgca tctgttcctc ggcctacgat
    36181 ccgtgatttt aattccgcta aatctggcgg agtcaaaaag atgaatacac catcgggcac
    36241 tttttctttg acttgttttg ctccttggac ttcaatctcc aagaaaacat cttttccttc
    36301 atccaatgtc ttgttgatat atgacaaagg agttccataa taattcccga catattctgc
    36361 gtattccagc atctctccag cttcgatcat tgattcaaac tcttctttgc ttcggaagaa
    36421 ataatcaacg ccttcgacct ccccttcacg cattttacgg gtagtcattg agatcgaata
    36481 ctgaaaatca ttatcctcac tctcaaaaat tgcttttcgt actgtgcctt ttcctacacc
    36541 ggatggacca gacaacacga ttaataatcc acgctctgac atgacgacgt cctttcaact
    36601 agtctttttg tacttatcgt ttattttgca ctttttttct gcaactttca aggttatctt
    36661 taattatagc tagaaattgg taaaaaagct accctgtacc aagaggtcgt aaaaaagctg
    36721 tcctgcatca agtaataaga acagccaaac ataaacagct tctcatgttt ttcgtttggt
    36781 tggggttatt atcgcagatg caagcttttg aacgccgtgt ataagaggtc gtgaagaagc
    36841 cgattagttt cgagtatgaa gaaaaatttt gtgaaaatag tttctcacat ttttgcataa
    36901 atttggctta atac
//
LOCUS       DAJSMK010000018        36856 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.018, whole genome shotgun sequence.
ACCESSION   DAJSMK010000018 DAJSMK010000000
VERSION     DAJSMK010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36856
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.018"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(324..893)
                     /locus_tag="ON488_000925"
     CDS             complement(324..893)
                     /locus_tag="ON488_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCR3231138.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(967..2256)
                     /locus_tag="ON488_000926"
     CDS             complement(967..2256)
                     /locus_tag="ON488_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231139.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESENKSKLTKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQAFAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2610..3458
                     /locus_tag="ON488_000927"
     CDS             2610..3458
                     /locus_tag="ON488_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HCR3231140.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPVPVR"
     gene            3472..4545
                     /locus_tag="ON488_000928"
     CDS             3472..4545
                     /locus_tag="ON488_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HCR3231141.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4535..6706
                     /locus_tag="ON488_000929"
     CDS             4535..6706
                     /locus_tag="ON488_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HCR3231142.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSGNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6818..8989)
                     /gene="copB"
                     /locus_tag="ON488_000930"
     CDS             complement(6818..8989)
                     /gene="copB"
                     /locus_tag="ON488_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HCR3231143.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9009..11195)
                     /locus_tag="ON488_000931"
     CDS             complement(9009..11195)
                     /locus_tag="ON488_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HCR3231144.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="ON488_000932"
     CDS             complement(11195..11404)
                     /gene="copZ"
                     /locus_tag="ON488_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HCR3231145.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11417..11857)
                     /locus_tag="ON488_000933"
     CDS             complement(11417..11857)
                     /locus_tag="ON488_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HCR3231146.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(11931..12404)
                     /locus_tag="ON488_000934"
     CDS             complement(11931..12404)
                     /locus_tag="ON488_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HCR3231147.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFMVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
     gene            complement(12714..14180)
                     /locus_tag="ON488_000935"
     CDS             complement(12714..14180)
                     /locus_tag="ON488_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3231148.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(14491..16575)
                     /gene="cadA"
                     /locus_tag="ON488_000936"
     CDS             complement(14491..16575)
                     /gene="cadA"
                     /locus_tag="ON488_000936"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCR3231149.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            complement(17099..17458)
                     /locus_tag="ON488_000937"
     CDS             complement(17099..17458)
                     /locus_tag="ON488_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HCR3231150.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(17488..17829)
                     /locus_tag="ON488_000938"
     CDS             complement(17488..17829)
                     /locus_tag="ON488_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231151.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(17826..18500)
                     /locus_tag="ON488_000939"
     CDS             complement(17826..18500)
                     /locus_tag="ON488_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCR3231152.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            complement(19295..20593)
                     /gene="asnS"
                     /locus_tag="ON488_000940"
     CDS             complement(19295..20593)
                     /gene="asnS"
                     /locus_tag="ON488_000940"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HCR3231153.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(20633..21823)
                     /locus_tag="ON488_000941"
     CDS             complement(20633..21823)
                     /locus_tag="ON488_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCR3231154.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(21844..22371)
                     /locus_tag="ON488_000942"
     CDS             complement(21844..22371)
                     /locus_tag="ON488_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HCR3231155.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(22418..25207)
                     /locus_tag="ON488_000943"
     CDS             complement(22418..25207)
                     /locus_tag="ON488_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCR3231156.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDSSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAIYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKEIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHAFFADIAHRGTGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(25354..25554)
                     /locus_tag="ON488_000944"
     CDS             complement(25354..25554)
                     /locus_tag="ON488_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCR3231157.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(26006..26326)
                     /locus_tag="ON488_000945"
     CDS             complement(26006..26326)
                     /locus_tag="ON488_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231158.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(26627..27745)
                     /locus_tag="ON488_000946"
     CDS             complement(26627..27745)
                     /locus_tag="ON488_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231159.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            28216..29523
                     /locus_tag="ON488_000947"
     CDS             28216..29523
                     /locus_tag="ON488_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCR3231160.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFDNLF"
     gene            29642..30841
                     /locus_tag="ON488_000948"
     CDS             29642..30841
                     /locus_tag="ON488_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCR3231161.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYAWQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(30868..32136)
                     /locus_tag="ON488_000949"
     CDS             complement(30868..32136)
                     /locus_tag="ON488_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HCR3231162.1"
                     /translation="MEKQLPSPMRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLITLTL
                     FGTITTHLFGGSVGREGTAVQMGGSLADNTARLFRLDKAEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(32299..32946)
                     /locus_tag="ON488_000950"
     CDS             complement(32299..32946)
                     /locus_tag="ON488_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HCR3231163.1"
                     /translation="MEQTIKPYQYFFIKREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILNHELPEIDTFLTTVLDVKLTKAQAERALEKLKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
     gene            complement(33354..33857)
                     /locus_tag="ON488_000951"
     CDS             complement(33354..33857)
                     /locus_tag="ON488_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HCR3231164.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(33980..34744)
                     /locus_tag="ON488_000952"
     CDS             complement(33980..34744)
                     /locus_tag="ON488_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HCR3231165.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSADQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            34851..35126
                     /locus_tag="ON488_000953"
     CDS             34851..35126
                     /locus_tag="ON488_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HCR3231166.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            35842..36792
                     /gene="yidC"
                     /locus_tag="ON488_000954"
     CDS             35842..36792
                     /gene="yidC"
                     /locus_tag="ON488_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HCR3231167.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
BASE COUNT        10594 a         7760 c         6535 g        11967 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1081 atcggtgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1141 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1201 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     1261 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaaatgc
     1321 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     1381 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     1441 aagccattct tggtaaagta cttttgtcag ctttgatttg ttttcgctct caaattcgct
     1501 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     1561 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     1621 tgctagataa tttttttctt ttattggcaa aatctgctct tctctaaata gcaattcagg
     1681 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     1741 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     1801 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     1861 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     1921 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     1981 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2041 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgga tgggacagtc
     2101 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2161 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     2221 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     2281 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     2341 tatttaaata cgcaaatttt cctcattatt tttaatttta ctcaatttaa tcgtattctc
     2401 atttcaaaac gaatgtactt taaaaaaaca taataaaatc actttgcttg taggatgtat
     2461 tcccttccat tacaatgaaa taaatagcaa ttttatgaga aggtgatgtg aaaatggaag
     2521 aaaaaatcga agaatccaaa caaaaaatcg atcagttgat acaagaatta gaaaaagcgg
     2581 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     2641 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     2701 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     2761 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     2821 ttaccacgat cttgttggca gatgagatca atcgcacgac tcctcgtact cagtcagcac
     2881 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     2941 atcatttttt tgtcttagct acgcaaaatc caatcgagta tgaaggaaca tatcctttgc
     3001 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3061 acgaactttt gctactttta gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3121 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3181 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagccatgct gccatccagc
     3241 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     3301 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     3361 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaaaaaa caaatcattc
     3421 atactcttgt tgcacaaatt cctgttcctg tgaggtagat tgaggtagat aatggaaaaa
     3481 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     3541 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     3601 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     3661 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     3721 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     3781 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     3841 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     3901 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     3961 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     4021 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     4081 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     4141 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcacagtcc aaaatttgaa
     4201 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     4261 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     4321 ttggaagctg gcgatgagaa agcttttttc gcacacctaa aaaaatatgc aaaaaaacaa
     4381 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     4441 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     4501 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaatggg aaaaatggct
     4561 gtgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     4621 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     4681 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     4741 gtttttgtat tttccttcga agacattttc cttattatgg atcttacagt ttttttcgtc
     4801 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     4861 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     4921 ctatttgtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     4981 ggaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     5041 agcaaggcaa tttttctcca tgcggttgtt gtcgggaaac actcgattcc agtcattgac
     5101 tacagttctg cttatttgtt tcttaactat tagcgctatc ttgcctttat atcttccgaa
     5161 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     5221 gctttatgat acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     5281 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     5341 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     5401 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     5461 ctaccaaacc gttatggaag acaaagaaaa cattacattg accctaaaaa aacaagcttt
     5521 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     5581 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     5641 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     5701 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     5761 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     5821 cgaagctgtc gaacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     5881 cggacatact ccgaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     5941 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     6001 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     6061 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     6121 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     6181 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     6241 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     6301 accagcttat aaaatcgtct tattcagcct tggggtgtgt ttatacgtct tgttgttctt
     6361 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     6421 tgcttctact aatacgattg catatcaaaa acttcttaac catttggaaa cattggtacc
     6481 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     6541 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     6601 agatccggta aatttcgata aaaaaaccta tttagaaatt acgcatataa taagaaaaac
     6661 ggtatacaaa aaagttctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     6721 agaatctact tctggaatgc cgagaaccag ctgcttgagt atcgattatt cgaaaaaaag
     6781 gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc aatgtcaaag
     6841 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     6901 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     6961 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     7021 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     7081 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     7141 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     7201 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     7261 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     7321 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     7381 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     7441 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     7501 tcacttgttg gtttttgact gttgcctcta gcccaactcc tgaaagattt tttagatttt
     7561 cggcttgata aggcttgatt tcatgttctt tcaaataatt cataatacca acagccaatg
     7621 gatgattggc attcgcttcc aatgctccta aatattgaag gatttcattt ttattgaacg
     7681 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     7741 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     7801 gtaatccgtt tttagctgct attgatgtag agcgagcaac aactaatggg atagctaaac
     7861 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     7921 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     7981 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     8041 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     8101 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     8161 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     8221 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     8281 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttt actgattctg
     8341 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     8401 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     8461 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
     8521 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
     8581 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
     8641 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
     8701 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaatttc
     8761 ccatgtgcat ggaatgatcc atgccgccat gatcgtgatc catgtgcatc gaatggtcca
     8821 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tggtccatct
     8881 ggctatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
     8941 ctacttcttt tttatgttca tgttttttct ccatatcgtt cccattcatt tttactccat
     9001 cccttctctt actttttcat gtgccgattt aagctcaggg agttcaacaa tacactgacg
     9061 gaactaaacg ccatcgctcc tcctgcaatg attggattca aaaagcctag tgcggcaaaa
     9121 ggaataccaa tcgtattata gacaaaagcc cagaaaagat tttgtttgat ttttctcaat
     9181 gtcaccctag acaactcgat tgtttgtgca atggatgcca aactgctact catcagcgtc
     9241 acatcggctg tttccatcgc gatatccgtt ccacttccca ttgccatacc aacatcagct
     9301 aatgctaaag ccggtgcatc attgattcca tcgcctgcca taccgacttt tttgccatct
     9361 ttctgaagtt tttctacgta ggctgcttta tcctctggaa gtacttcagc aaagatatgc
     9421 tttggatcaa taccaacttg tttaccaatc gtttcggctg ccagtttgtt gtctcctgtc
     9481 agcataaaaa catctaatcc tttattctgg agctgcttga ttgcttgttt ggcttctagt
     9541 ttgatttgat cagccacggc aatcaacccg atcacttgct tttcatcagc taaaaacatg
     9601 actgtttttc cctgctgttc taattctaac gcgtgttctt ggtattcatc aaatgatagg
     9661 ttcaattcaa ttaatcgttt acgtgtaccc gcaaaatagc gtactccgtt aatcgtaccg
     9721 ctgattccag cacctgggtg agctgtaaaa tcaatcatat cgtatgttgc tgcttcttgc
     9781 agttttccgt attccacgat tgctttacct agtggatgtt cagaagcttg ttctaaagta
     9841 taaaaaatag ataggacttc tttagaaccg actagatctg taactttggg ctttccttct
     9901 gtaatcgtcc cagttttatc caaaacaatg ctgtctaagt gagcagctgc ttctaatgct
     9961 tctccgcctt taattaaaat tccatttcgt gcaccaacac ccgttcctac cataatagct
    10021 gttggagtcg ctaaacctaa tgcacatgga cacgcaatga ctaatacaga gacactatgg
    10081 atcaatgcga gttgccaatc accagtgatc aaacctgtag ctatgagcgt gataaacgcg
    10141 atgactaata cgatcggaac aaaaatccct gagatccgat ctgcgatttt ttggattggg
    10201 gctttgctcc cttgagcatc ttccaccatt tgaatgattt gcgctaatac tgtctgcttg
    10261 ccgacttgtg tgacttccat gtgtagcaga ccattcgtat tgattgtccc gccaaaaagc
    10321 gtgtcatccg gattcttttc tacaggaaga ttttcaccag taagcatact ttcatctatc
    10381 gcactgcttc ctgaaataat tcgaccatct gctggaatct gctcaccagg acggatgact
    10441 agttgatcac caacgactac ttcttcaatc gctaacgttt cttctttccc gtttcttatc
    10501 acttgggcgg tttttgtttg aagagacatc aattgtttga ttgcattacc tgttttcgtt
    10561 tttgctgtat gttccaaata tttgccgagc aaaatcagcg tgatgatcat actgctgctt
    10621 tcaaaataaa gatcttgggg gtgtccacgg aaaaatccgt tgtaaatgct caatgcaaag
    10681 gcagccgatg ttccaattgc taccaataca tccatatttg gtgctttcga cttgattgca
    10741 tggtacgcac ctttataaaa acgagcaccg acataaaatt ggacaggagc agacagcact
    10801 aactggacga ttggaaaatg aaaaaagtga acaatcgccg catggcttcc taacatcata
    10861 gcaatcattg acaacatcaa cggcaaagtc aaaaccgtac tcaatataag atcgaatagc
    10921 atttttttca aatacgcttg cttttcttct gcaatttttt gtttgtgggc ttcatcgtac
    10981 aaaattgcac catagccgat gttttctacg ctttggatta atttttcagt ggtcgtccct
    11041 tcatatttga cacttgcttt ttcagtggcc aagttgactg tggcattgac cacaccaggt
    11101 tgtccgttca gctctttttc gatcctagca gaacaatttg cacaagtcat acctgtaatg
    11161 acgaacgtat ccattttggt ttctgctgtt gccatcaaat cacctctgct ttataaccca
    11221 atccattgat tgcttgacaa atcttttcgg attgaacttt tgtttcatca aacttgaccg
    11281 taccgtttgc ttttttcaaa tttactttca ctttttgcac gccgtcaagt gcgcttactg
    11341 tttcttctac tcttgctgca caatgattgc agctcatacc ttcgattgaa aattgttgtt
    11401 tcattttttc ttcctcctat tgatgttgtt tacattcaca ttgacctggg atacagttac
    11461 attcgatcgt atctactggt tgcttttgtt ccagttgttt caaaatctca ttgatatctt
    11521 cttgagtcaa agtggcttct tctactagat ccgcaatcgt ctctccaatc ctttttgcac
    11581 agatatggga aaaaagattt tccgtcgcac tgcgaactgt ttccatctcc gagacagctg
    11641 gatgataaat gaattttttt ccttcttgtt ctgtccagat cacttctttt tttaccaaac
    11701 gacccagcaa agttttgatc gttgctggtt tccaatccat cgaatcagct aagatctgcg
    11761 tgatttcttg ggctgtcgtc tgtccaagtg tccaaataac acgcatgatc tcccactctg
    11821 aatcactaat ctttactggc gttttgactt tttccattta tttcacacct ttcgtttaca
    11881 aatgtaatca ttaacttatg aatacagatt acacttgtaa acaaaaactg tcaattattt
    11941 ttgctctcta ttttcaattt agttaaaaat tcttgtttct ctcgtcttgt tttaaggatg
    12001 atcagtttat ttcttgcatt agctacttgg atcagctgct gtatttttgg ttcattgttt
    12061 ccttcaaaat gccagataaa agataaaaat tctaagtatt tcctgtttag tttctccgaa
    12121 aatgattcag gcatatctgg ccgagatttt ttgtttatct ttctttttag agaacgccaa
    12181 actactcggt agatggcgag ataacgcggc actttaagcc aaatgatctt atctgcttct
    12241 ttaatccttt cctctaacgt agaagtataa tttccttcaa cgatccatga cggattagat
    12301 accataaacg attgctgttc ttgcaaaaac cacttttttg cctgaatgcg gaaagccggt
    12361 gatttctttg atcttccttg cgagggacga ttttcccgac ccactttgtc caatcacgat
    12421 gatcttcatt cttctccctc acttctcttt ggaatttggt tcgatcatac cacttataac
    12481 gccgcaaaaa aacaagggac tgtgacaaaa gtcgtgtcaa agtcccttgt ttcgaataaa
    12541 tggtgttcaa tcagctgacc ttcagcatta gctcaaaaaa cggcaaaata tgaggagcta
    12601 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    12661 cggtgttcca gaagtagctt ctgtcacaac ctcttgtaac aagtatttct attttaaggc
    12721 tgaaccactg tttctggttc agtaatttct ttgtttttgt ctcgacgagc aattgctggc
    12781 aagatcatac ctaataagat caagacaatt ggtgtgatga tattcgtgaa taattggaac
    12841 caccatgctt taggatcagc agtataatct acttttggca ccattcctag gatacatgca
    12901 aacgcagtga aggcaaagca ccaagcacca aagataaaac cgatttttgg atttttaaca
    12961 aatttatatt cagaattgaa tttcttataa gctttattca acatcatata tgccaagaac
    13021 acccataggt aacgcattgg catgacaact gagttcaagt tcgtcaacca ttttactaat
    13081 tcattcatat ctttgatacc aaagatcggc aacaaaataa tgattcctac tagtatacct
    13141 gtcagaagat aaccattcac caatgtacct ttacgattac gtttacgtag ccagtttggt
    13201 acaaattctg gatccgcatc tgctaacaag atttttagtg gtgcatcaat tgaaaaggct
    13261 aatgcggaga tttgtccaat catgtttgtc aatgcgtaaa tgatcatcaa tgagttaccg
    13321 ataccatagt aattacctaa aatttgaaaa gcactgtatg ccccatttgc catcaagtct
    13381 ttagggatat tatcgctagc aaacagcata cccattgcga ctgagcctaa tacagcacaa
    13441 atccctacca ttgctgctaa gaagatcatc cctttaggaa attcctttgc aggatttctt
    13501 gtagagttga cataagggga tattttttcc gcccctccaa ctgcaaatac tagcatcgaa
    13561 acggttgtga aataactgaa atcaaatgtt ggaatatatg ttttcacttg attcatatgt
    13621 ggtgtggcaa attccatcgt tggattgatg aacggtgccg ttacagctaa aagaataaat
    13681 aagatcgaca tgacgaacat cgctgttccg gccagtccgc caatcacttt caaagtagaa
    13741 agtccttttg ttgataaata taaaaaggca agaaatataa taagtgaaat aactgctacc
    13801 atttgtactg acatcgtatt tacgatattt ccatttcctt ggactgccca accaccagca
    13861 atcagaattg cttgaggctt ttgtgccaaa taaggaatat ggacgaccca gtaagtccaa
    13921 gcggcatagt atgccagtcg tttattagat gtcgtatttt cgacccatga actgacgcct
    13981 cctttactat ccttgaaggc tgatcctaat tgtccaacga tcaatgcgta tggaataaaa
    14041 taaatggcca aaatcaatag ccaagaggtg acaactgata ctccttgctg agcatagtta
    14101 ttaactacat tccccatgcc ccaaaccatg ttaaatgcaa ttaacgcaac agtaaaccag
    14161 cgtaattgtt tgttgttcat tcgttctctc ctttatgata aaaatttgtt atccagatgt
    14221 aatcatattc aatttttaac aaacttacaa gacagtgtta ttttatgtgt gtattctttt
    14281 atttaataca catcgttttt tcatattttt tccatcaaaa aaataagtta ttttctttta
    14341 tttcattgac cttattgaat ttcaagctat tttgaatttt ctgcaaaatt aaaaacatta
    14401 gttattttat aatcctatct attttcttta catttttcat taagaaaagg atataaaaaa
    14461 aagaggacgt tcattcgtcc tcttcattga tcaacgttta ttttttacat gcaagcttcg
    14521 catggcattc aaaacagcta atactgtcac cccaacatct gcaaatactg catctcccat
    14581 tgatgcaaaa ccaaaagcac ctaaggaaag taccaaaatt tttatcccaa tagcaaagac
    14641 aatgttctgt ttgacgattt tcaatgtttt ctttgctaaa tggattgctt ctgcaatctt
    14701 cgatggttga tcattcatga tgactacatc tgctgcttca attgcagcat cgcttcccaa
    14761 tccacccatt gcgattccta catctgctct tgctagcacc ggtgcatcgt tgattccatc
    14821 tccgacaaat gcggtctttt tattgttact ttgtaagatt tcctctaacc gctgcacttt
    14881 atcttctgga agcaattcgc tatatatctt gtccacgcct acttgcttcc cgatatgatc
    14941 agcaattttt ttcgagtcgc ccgtcaacat gactgtgttt ttcacaccag cctgttttaa
    15001 ttgaaccaat gcgtctacgg catcttcttt caaggtatct gcaataacaa gataaccact
    15061 gtaactttga tcgatcgcta gataaagcaa tgtaccgatt tcttgacttg aaggaaaaga
    15121 gatttcaaat ctttccatca atttgtgatt acctactaat acttgtttgc catcaacttc
    15181 agctaagatc ccttcacctg caaattcctg gatattagct gttggtaaaa gcggacctgc
    15241 gtagccttct aaaacagatt gagcaatcgg atgtgtagaa aactgttctg cacttgcaac
    15301 atattgcata aatttctttg gatcaattcc tgttggatcg atcgtctgga tcgaaaagtc
    15361 acctttcgtt aatgtgccag ttttatcgaa taccactgtc tcagtttgtg caagcaactc
    15421 caagtaattt gaacctttta ctaatacacc gattttactt gctcctccga taccgccaaa
    15481 gaaactaagt ggcacggaaa tcactaatgc acatggacat gagatcacta aaaatgtcaa
    15541 tgctcgatag atccattcag aaaacgccgc tctagaaaca acaagtggag gtaaaacagc
    15601 taataaaacg gccaatccta caacgactgg tgtgtaatag cgcgcgaatt tagtaatgaa
    15661 attttcagct ggtgcttttt tactgctggc attttctact aattctaata atttgctgat
    15721 agtagaattt tcataagatt tttctacttg aactaaaaat ggtttatttt tattgataaa
    15781 tccgcttaat actgtttcac caacatatac agatttaggg actgattctc ctgtaagtgc
    15841 tgacgtatcg actaatgatt ctccttcgat gatcgttcca tctaacggta cacgttcacc
    15901 aggcttcaca agtacaaact gaccgatcag cacgtcttca gggttcacgg tcatcaatcc
    15961 ttccgccgtc tgcacgtgag ctgtttctgg acggatcgcc atcaattcgc gaatcgattt
    16021 tcttgaatga ctgactgcca atccttggaa atactcgccg atttgataaa atagcatcac
    16081 tgctacggct tctggatatt caccgatcaa catagcgcca atcgtagcaa cagacataag
    16141 aaaattctca tcaaagattt ttcctttgac gatattcatc actgccttct tcactacatc
    16201 atatcctatc agcagataaa tcaataaata ccctatcaag cgaattggtt cattaaaatc
    16261 aaataatagc aataaagcga tacctgcaag ggaaaataaa atccggaaca gcgtatttct
    16321 ctttttttca tttccatgtt cagatacttt ttccttatct atttctgtta ctttgacatc
    16381 tggttctaat tccttcacta ctttttttgt ttcttgttca atcgtagcca aatgatcttc
    16441 ctctgcgtca atcgttagtt ttccagaagt gaagtttacc gttgcttcct tgactccatt
    16501 gattttctga actccttttt cgattttcat tgcacagttc gcacaatcta aaccttctaa
    16561 tctgtaactt ttcattttaa tgacctcctc gcctcaacat atgaatatct cttcataact
    16621 aattataaat gaatggttat tcatatgtca aggtatccga aagaaaaaat gaaaaacatc
    16681 tgcatcggaa aatttcttcc atacagatgt tttggcttat tctttctttt tctcttcgat
    16741 cattgccact gctcttatcc aacccgcact tgccttcttg atcttgacag gatagcaact
    16801 aagtttgaag cctgttgctg gcaatttgtc taaattcatt aatttttcga taggacaata
    16861 tcttttttca atccctgcaa aatgtccttc ccagatatac gaagctccac tacgctttca
    16921 aaaatataga aagagttctt taatgaaaat tatttcaact ttccataaac agtaacccca
    16981 tataaataaa agacgtaaaa gtcacataga agaacttata caggaaaacg catagagtca
    17041 ggtgaaatac atgtatccca cctggctcta tgctttatct aacctttatt attctctttt
    17101 atacaatttc tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa gattgcttgg
    17161 caaaaggtat ccctatgatc gtgatacata gaaggatgcc gctgacgaca tgtgcgagag
    17221 caattggtag gcctgaaacg atcagccaga tgatattaac gatcaatgac atgccagact
    17281 ggtgataaat tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc ttaaaacatt
    17341 gcataccgat tgggatacct atgatcgtga tacaccaaag tatccccgct gctaaccagc
    17401 taagaccacc gattagtccg ccgaatataa accagatgac atttcctaaa caactcattg
    17461 tatttctcct tctattactg tttttgatta aaactgggca aaaattgatt ttattcttct
    17521 ttttttagct tccagcatca agtattctgc aaattttttt tggatttctt ccgtattttc
    17581 ttttgttact aatgtgtgtt ggattagttt tcctgatggt cgctgatcca atcgttcttc
    17641 tgactgttgc acgtccgctt gcgcaaatcc gataatccgt ttttcttttg ttacagcaac
    17701 gagcaatagt ttattcttat catttaggtc agctgccgtt tttgctttta cgaatgattc
    17761 tggatgatca gtaatcagct gattgatttg aggtaaatct tcttttactg cccaccttat
    17821 ttccatcatt tttcactttt ctttcgctca tttttatctc cactaaaaaa atcgactgcg
    17881 acaattgcat ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt tgggtggacc
    17941 ccatcttctc ttgtatattt cgaaaaacca taagcaatcc ctaaagcatt gaatatacca
    18001 tctaaaggaa ccagcaatgc gccatattcc ttagcaagtt tacgaacaat ttggatttta
    18061 gggtctaagt ctttacgcca gccatgacgg tcgtcggtta taggaagtac aaacggctcc
    18121 atcaagatga tgttgcagat ttccgctgtt tgaagttcat ttagtaattt tcgataaacg
    18181 gattcaaatt gctgagcaga tttctcagtt ccgaatatag cctgatcgct agtattatgc
    18241 caggtatcat tgattccgat caaaatcgat acatagtcag gttgtaaagc taaacaatct
    18301 tcttgccagc gtacttgcag atctgcaatt ttgtctcctc ctatcccacg gttcatgcat
    18361 tcaaattcca tcgttggata ttgggagatt agttttccgg caatcaaaag tggataacct
    18421 ttacctagat cagttgcttc tgctcggtat cttcctgcgt ctgtaatgct atcaccgata
    18481 aataatatac gttttttcat ttgtcaaaaa ctcctttttg aataaaacga tgattttctt
    18541 ccttatatta tcccataagc cctatcaaga cgaaagagaa aatatatgta taaaaaatga
    18601 caccagccta gttccttcaa acaattgaat gaacgctcat caagtgtcta gttttttatg
    18661 ctattttttt cttaacgtgc cggattcccc ttgattcctt cgttgtttgg tccagagaga
    18721 tcgatcacac ccaagcttcc gtcaatcaga ccactgatga cgccatcgaa acatatattt
    18781 ataggctcat ctaagacttc tagtaaatgt ccctttacta atatctcttc tagattgctt
    18841 gggatagatt ggtcataact ttatctggtc cgatgatttc aagggtgaat tgaacttaca
    18901 tatggattat tgcatgctga aaatacggac ctactccatc ttcgaatgtt actattagtt
    18961 tgttttcagg tgctagatgc tgctttattt caacagcaga agcatcatca aatcagattt
    19021 ccatttgaat taccttcttt gtaaatgttt gattgattgc gatttcgtta tagaaccttg
    19081 tgaatcaaat agcaatttct tttgctttct tctcttgtct gctggaaact tccattatcc
    19141 cgtatttaaa aaaaagaact gcgagagttc gcagttcttt tttttaaata aacgttgctc
    19201 tccggccaca agtcacaata gtcatcaaac atgaaaaact gttttttgaa attactcctt
    19261 gtgactcgga gctgaacggc aggcgcacaa cctcttatgg ataaattcgg ttcaacaaac
    19321 gtgggaatgg aatagcttca cgtacatggt cgataccagc aatccaagtg actgttcgtt
    19381 caagacctag accaaaacca gagtgcggaa cagaaccgta tttacgtaga tcaagatacc
    19441 atgaatattc tttttcatcc aaaccgtgat tacggatttg ttctagcaag aaatcatagt
    19501 ccgttgcccg ttcgcttccg ccaataattt caccgtaacc ttctggtgcg atcatatctg
    19561 cacaaattac cacgtcttct cttgttggat gtggtttcat gtagaatggc ttgatggctt
    19621 ttggatagtt taggataaag acaggctgtt cgaatgaatt cgcaatgaac gtttcatgag
    19681 gtgaaccaaa gtcttcgccc cattcgatgt catcaaatcc atttttcttc agtaattcga
    19741 ttgcatcatc gtaagtaata cgagggaatg gcaattttgt ataagttttt aagacttctt
    19801 tgtctcgtcc tagtacatct aatgcgtatt cgcaatgatc taaaacattt tgtactaaga
    19861 atgctacata ttgttcctgt acttctaaac tttcttcttg atgagtgaaa gccatttctg
    19921 gttcgatcat ccagaattcg atcaaatgac gtcgtgtttt tgatttttca gcacggaaag
    19981 tcggaccgaa tgaaaagact tttccgaaag ccatagcagc agcttccatg tataattggc
    20041 cactttgaga taaataagct ttttgatcaa agtaatttgt ttcgaataga tccgtagtgc
    20101 cttctggtgc agaaccagtc aagatcggcg gatcaatttt gacaaaatga tgttgattaa
    20161 agaattcata cgttgcacga atgatttcat ttctgatctg cataatcgca tgttgtcttg
    20221 aagaacgcag ccataaatga cgatgatcca tcaagaagtc tgttccgtgt tcttttggtg
    20281 tgatcggata atcgtggctc tcgcttacca cttccacatt tgtaattccg atttcataac
    20341 caaattttga acgactgtct tcacggattt ctccagttac taacacggat gtttcttggt
    20401 gtagattttt agctgtttgg aaaacttctt ccgacacttc gctttttaca actacacctt
    20461 ggaaaaaggc tgttccgtct cttaattgta aaaatgtgat ttttccgctt gatcgcttat
    20521 ttgcgaccca agcgccgatt gttactgttt ctcccacatg gtttttcgaa tcgatgattt
    20581 gaatttgttc cacgtatgac tctcctttta tattccttga atttcttcag gattaatttt
    20641 gacttttact ctcaataaat tgcttgattc tgcgtaccgc ttcttctaac gtagcgcgat
    20701 cagtagcata actcatgcgg acattttctg gtgccccaaa gccttcgcca gtcacaagcg
    20761 ctacccctgt ttcttctaaa agatcttcta cccattgtgt gacattttca tatttacaca
    20821 tgcgtagcgt ttcttttaca ttaggaaaaa gatagaaagc tccttgcggc ttttcaagag
    20881 aaacacctgg cagttctgcc acaagcggat ataacgtatt caggcgttct tcaaaggcgt
    20941 tccgcatttc ttctactgta tcttgctcac ctttcaatgc ttcaacagct gcatattgac
    21001 tgactgctgt cggattactg gttgactggg aagcaacagc aatcattcca ttgatgatct
    21061 cagaattccc caccgcataa ccaatgcgcc agcctgtcat cgcatatgtt ttagacacgc
    21121 cattgatgat gatggtctga tttttgattg cttctgaaat cgttgcaatt ggagtaaact
    21181 cattgccatt ataaactaaa cgaccataaa tatcatcagc aactatcaaa atatcatttt
    21241 ttactgccca ttcaccgatt gcctgaagtt cattcttgct ataaatcatt ccagtcggat
    21301 tcgatggaga attgatgatt acggcttttg ttttttctga acgtgcttgt tctagctgtt
    21361 caacagtaac tttccagcta ttggattctt cccctttcac aaagacagga agtccttctg
    21421 ccagttttac ttgctcaccg taactgaccc agtaaggcac aggaatgatg acttcatctt
    21481 gcgggtcaag gatcgtttgg aaaagggtat acaaagcaaa tttcgctccg tctgttacga
    21541 ctgtttgtga aggttcatag acaagtccat agtttttctt cagataatca acgattgcct
    21601 gtcgaagctc tgggattcct gctgttggtg tataatagct agctttccca ttgcggattg
    21661 cttcgattgc tgcttcttgg atgttttctg gtgtcgcaaa atccggttct cccacagtca
    21721 aactcagcac atctctgcct tttgctttta atgccttggc ctttgccgca gctgccaaag
    21781 tgacagacgg ttctaatcgt tttgttcttt ttgataactc catcccattc attcctttac
    21841 cttttaaatt cccttgattg tcttgacttc atctccagat tcaaagccaa tcaggtaata
    21901 attcagtttc ccatttgttt cttttcctac tacttcccac acaggctgat catcatacat
    21961 ccctaaagca gctttttcga tttggatttc aggatgggcc gcagcaattg tctgttttgc
    22021 ttcgttttca gtcagtccct ttgtttgatc caatactttt actttttcac cagatttagg
    22081 aatgataacg gcgatttctt ttcctttatc atttgtacct gtcagtgaaa agtatgtctt
    22141 ctttcgagta aaccaataaa aatgatcggt ttcctcaaga tttgcatatt tctttgcgat
    22201 ttctactgct tctttcttcg cctgcaccgc cggacgactg gaacgcaagt aaaaaatcga
    22261 gctgatcacg atgaccgcta ataaaaatac gatcaagcca agtaacacgc gattaatcgt
    22321 tttttccttt gtctgttttt tcttcaaggg tcgtcgctcc tttatcttca ttccttttca
    22381 ttatagcaga ttttaattat gaaaaaagac agctcctcta acttccttct tcatttttct
    22441 ttaagaattc atggatatcc tgatagattt cctccatagc tagctctttg atcggtactt
    22501 ttttcggtaa tgcatggatg atccgtgcgc catattttgc agtgactagt cttcgatcca
    22561 aaataagcaa tacgccacga tctgtctccg tccttatcaa gcgacctaat gcttggcgta
    22621 acttcaaagc tgctttaggt acggattcct ggtaaaaagg attgatcccc tctgattcta
    22681 aataagcgtt cctagctttg accatcgggc gaagcggatt atcgaagggt aaacgtgtga
    22741 ctacaacgat ctgcaaagca tctccaggca aatctacacc ttcccaaaag ctgtcagcgc
    22801 caaacaatac gcttttttct gacaaaatga agcgtttcaa aagcttctcc cggcttccac
    22861 caaacccttg agctagtatt tctcgtcctt tttctagcat agacagatgc attttctgat
    22921 agaccttctg caaaacatca tgagaagtga ataacacaag tattggccga tcttcttgtt
    22981 cgatcagacc tgtaagtgct gtctctaaat aatcgatgta tgcttgattg ctgacttgat
    23041 ggacggcagg tgcctctttt ggcacataga tccttgcctg tttctcataa tcataaggag
    23101 aggcaatcac tttaagaggt gctgcttcaa tgccaagcct cttagagaga tagtgtcgat
    23161 tagggccgat cttcagcgtt cctccaatat aaagaatacg atcatatcga ggataccaaa
    23221 cagtcgacgg caacatagcc gcttggaaat catggagatg aaaaatcatc tgctgcgctg
    23281 tgttcccagg aacgaaccaa tggatcaaat gatctcgcca gtcttccagc cattgatcca
    23341 tcagcaagta ctgcttgtct aattgatcaa ataagctata taaacttgct aaatcgatcc
    23401 gcatctggtt tgtccagctt tcttggataa tctcaaaagt cagacgcatt tgtgactgta
    23461 gctgctgaat ctcctgataa aaaagctgca ggtgatcaat ggctgtccca gattccagtg
    23521 gcagctgatc cagcatctct tttgtcatca tgacttcttc tggatactgt ccgttgggtt
    23581 gcttgccgct cactaaactc attaatcctt ctgccataca aatctgtgct tcgcatagcg
    23641 cagaaagttc ttctcgataa atcgataacc agcgtaaggc ttcatgttct ttcggtaaat
    23701 agctttgtat tcggtcaaac agctgatttg gttcttctaa ttgctggatt tgtttatgga
    23761 aatagttaat acttaatcgt ttgtcattta ctttttcagc gatttccggc aaatgatgta
    23821 cttcatcgat caacaaaaat ggactagctg gaagcaatgg ttcttttcgc tgtgtttctt
    23881 gtactaaaaa cgcatgattg acaatcaaaa aattactttg cctgattttc ttttgcaaga
    23941 aacgaacaaa gtcttgttcg taaaacgact gatttcttgc taaaaaccca gtacctctgt
    24001 gcgcgatatc tgcaaagaat gcatggttca agtttgttaa atgtaattca tccaaatcac
    24061 cggtcttcgt ttgcgtcagc caaactaaga ccgccatttg atacaaagca tattgttttt
    24121 gttctggtgg ttccacaagt gttcctttaa atcgttgcag gtcgatatag tggcgataac
    24181 ttttgataat tacaggttgt atgggctgat ctagcaattg attcagcaat ggaatttctt
    24241 tttctatgat ctgctgctgc aaaactagcg aaacggtact gatgacagcg ggtttttcag
    24301 gtgtagccaa ataactcaat ggcaacagat aaccgattgt tttacccatt cctgtagctg
    24361 cttcgatcat caaatctttt gattcatctt ttgtgaaatg gtcgtagatc gcattcatca
    24421 gtctgttctg ttcttttcga tacatcagtg ttttaccaaa catcttttct tttgcttgtt
    24481 tttttcttgg atatgtccgc tcgccgtaat ggacggatgt gaatagttcc acttcttttt
    24541 tctgcaaagc tagcccatcg acgatttcta atgaggaatc aagtggctct ggtttttctt
    24601 tcatttcttc aatcacatga taaatgaaac gactcgtatc catacctgtg tgtctactta
    24661 atcgcgcaat ctgctctaac gtgatgattg gcaattttct catccgttct tcgatcagca
    24721 aaagaagttg acctgtcact tcggcatcac tatctgcctg atgaggattc tcatgaataa
    24781 atccaaggct ttctgacaaa tcagctaagc gaaagcttgg ttccgtcggc aagaaaattt
    24841 gtgcaagttc tactgtatcg atgcctggta tcttcaaact aggaagtccg catcgcatga
    24901 gttcatggtt caaaaaatta taatcaaaat aaatattatg cgcgacaaat atggtgtctg
    24961 ccaaaagatt gtaaatcgtt tgggcgacat cttcgaaata aggcgctttt tggacgcgtt
    25021 gattcgtgat ccctgttaaa tgctggattt gttttgaaat cttccgccct ggatgaatat
    25081 cgatcgaaaa acgtgaagtg atccgacctg attcaatcat gacgcagcca aattggatga
    25141 tccgatcttc ttttggattc gtcccagtcg tttcgatatc aacgactgca taagttcttg
    25201 gtttcaaaat atcttcctct tctcctgcct ctaatgttct tttgaaatta tactacaaag
    25261 tgcagaaaaa tactctcatc gctttttaaa gaaaatagac aaaaacgccc agacacgcaa
    25321 atgtctgggc gtttattttt tagtataggt taattaagct ttagtaacgt ttgttgcttg
    25381 aggtccgcgt tggccttctt caacatcgaa agttactgct tggccttctt ctaaagtttt
    25441 gaatccgtcg ccttggatag ctgagaaatg aacgaataca tcgtttccgt tttctgcagt
    25501 gatgaatcca aatccttttt ctgagttaaa ccattttact gtacctgttt ccataataaa
    25561 aatcctcctt gtgtatcaac acatattttg caattacttg aatggtgtat atctggaaga
    25621 tgtttatttg aaacaagcta ccacagatta ccgaacaaaa actactccta tagtatatca
    25681 taccgtttac aaaaaagcta gagtttttcg acttttttta ttaaaaaaag ttttctcagc
    25741 gattacataa agtgaaaaaa cgaacttttt ttaaaataaa cgacatattg ttcagttggt
    25801 gtttttttgc tctgatgttc ttctttaaac taaaaaaatt attctttctg actacttatc
    25861 ggttctgttt caacggtcga ggctggggaa gattctttag taggtctgat gttctcatgg
    25921 tatttctgat agcctatgac agtgaccaga agaacaaggc aaaccaatac gatcaacgag
    25981 attagttttt cttttttgct catatctata cctcataaat aacaggatga tgtccatcat
    26041 atttctgagt atgagtaaaa gcaaaagctg cagctgtaga atgtaagaaa tgccagcaac
    26101 tttcataatc acaggtcgga cagtaccaaa agtaaccaaa tcttggctgc aaagaccgtt
    26161 cttctgtttc aggaatcgca gaatcaagat ctgttgtctg tacataaaca tttttgtaca
    26221 gacgtgtgcc tgtaatagga gaccgctgtg tttcttcagc aaaaactggc tgacttgtta
    26281 aacttaggga tagaaacagc aaacaccata acagtctttt tttcataaag acctccttat
    26341 cgataagttt ttcccaatta aaatcatatc tcaagaacgc ccgttattca cattttgttc
    26401 ataaatgatg ttttttgtat cataatcgtc aaaaagaggt cgtgaccacg tcacaacctc
    26461 ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt tcacaaaaat
    26521 ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact tctgtcacaa
    26581 cctcttcctt aatactcagg tcaaaacact gatttcacaa cctcttttaa taacgaagaa
    26641 tcgctgtcag actcttttca tctggcgcat ctttttgatc caaaataaac actttcccgc
    26701 cattaatgat cacatcatct gctaatgcat tcaacacttg acgccgatca tattctgttt
    26761 caggatcttc accgaaacca tcagctaagt ttgacgtagc gataaataaa tgtgacactt
    26821 ttccttcttt cgcagctgga acgatatcaa ctaactgatc gatgaatttc ttatctaaga
    26881 gtttattgta ttcttttgat tcttgagctg cgagttcact tgacagcttc ttcgcccctt
    26941 cttcgatatc tctaaaggat agctgcgcag gagaagcaga aatcgcaacg tctgcacaat
    27001 aatagggatt tttagcaatt tttttgaaca tcgtctgatt ttctggtaat gcaaataaat
    27061 aaatcggcca ttgttcagga ttttcgaaag aatcctttaa gtacgtatca acagcttggt
    27121 aatagttgac ccaatcgatc tctacttctt catcttttgg atttacgcca tggaaagtta
    27181 ctccatctcg ggctccgcct cctccattag aagagaagtt caaaccgcca cctgtcagtt
    27241 cagatcccaa tgcagtaacg acatcaaccg gtgccccttc tggtagagat acttctttta
    27301 cttgtttgtt gctgacctca tacaatttca tggagtcgcg gttcaatccc aataaataat
    27361 aagaatagtt gaactgccca tttttgataa tagccagtaa ataaggaaga tcacttacat
    27421 agtattgatc gtctaccggg atactcaaac gatggatata ggtctggtca gcagttataa
    27481 tgaccgctac actcgtagtt gcactacgcc aaaacgaagg atctcctaac aaattttcaa
    27541 ttttttcttg gaacggagac cagtcatgtt cggaatattt tttctcaaaa cgtttctttg
    27601 cttctttcgc aaaatttttg aatttgatct gatctttttc cacatcttga tgggcgacat
    27661 gcgtattcag catgatcgtg acgaatggtc ctttagcgcc ttctgaagtc aattgtgtca
    27721 ataattcttt atcctttttt gccataaacg tacccctcct aaaaaaatca ttcctttgtt
    27781 tctatctaaa gtctaccaca acactatttt tccatacaat aaaacgtatc taaaaaaata
    27841 aaacggtttc tacggtttta aatttagcta tttttttaag ttatcttcat aatttcctca
    27901 attatttagc cccagtcttc aactattctt catgaaatgc tgataaacta agaaaaagaa
    27961 taaaagaggt ggatcttatg catttaatta tgattttcag tttattaagt attatcagtt
    28021 tatttgcttt cagcgcttcc cgcttattag atgcggaaac acggcctatt cctgtaaaag
    28081 tacgtaaaaa cgaccgctaa acttccataa cgcgcgttct tatcctaaag ttttttcaga
    28141 aacattgaaa ctctctcccc tctctgataa aattttaatt tgtagcgaaa caaattaatt
    28201 acaaggagat cggatatgtc cataaaaaaa acacgtctag tcctattatt ggctagtctc
    28261 attctttgcc ttgcttcttt tctaccagct gttgctgtgc aagctgaaga tacgttcaaa
    28321 gtaaatgcaa aagcagcttt tgctgtagat gcgcaaagcg gtaagattct ttatgatcaa
    28381 gatggagaaa aaaccatggg gatcgcttca atcacaaaaa tcatcggtct ttacatcgtc
    28441 cttgatcaag taaaagaagg aaaactgtca tgggatgata aagtttcgat ttcagattat
    28501 gcagaaaatt tgagtatcac cccagattta tcgaatgttc ctttgcataa agaaaacacc
    28561 tacactgtca aagaattatt cgactctgca atcatccagt cagccaatgc ttcaatggtg
    28621 gccttggcag aaaaaatctc tggcagcgaa gctaaattca ctgaacgaat gaaagaacaa
    28681 ttgaaagatt ggggaatcaa agatgcaaca atcgttaatg catcaggatt gaacaactct
    28741 tatcttggcg aaaaccgacc agaaggcact ggagaaaacg acgaaaatca aatgtctgct
    28801 caagatgtgg ccatcgttgc ccgccatttg atcttggatt tcccagaaat actggatgta
    28861 tcaagtacta cgacccaaat gtttggcgaa aatacgcaat caccagtgga aatggtcaac
    28921 tggaactgga tgctcccagg attcgttaat tacaaggaag gcgtggacgg attaaaaact
    28981 ggtacgactg agcttgcagg tgcttgtttc gttggtacga tcactaaaaa cgatcaacgg
    29041 atcatcactg tcgtattgaa tgcggacggc catgcggaaa acccgagtgc ccgcttcaat
    29101 gaaacagacc gtttgatgga ctactgctat gacaattggt cagaaaaaga gctcggaaaa
    29161 gctaacgcaa gtattcctag tctaaaaacc attgatgtaa aagacggaaa agaatcaaca
    29221 gttcctgttg tgcttaaaag ccctgtaaaa gtatgggtac gaaacgatat ggatactggc
    29281 aaattaacga tcacgccaac acttgacaag aagcaagtca ctgacaatga gatccaagca
    29341 cctatggata aaggtacaaa aatcggtacc gctacgatca ccttggcaga cgataaatta
    29401 ggctatttag aagacaacaa tgcaccatca acagagatca ttacggataa aacagtggaa
    29461 aaagcgaata tattcgtgat tggctggcga cgcgtcgcag aatttttcga caacttgttt
    29521 taattgaaca ataagaaaaa catctttcca tcggaaagat gtttttttgc tttttctagt
    29581 ttaaataaca gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt
    29641 tatgaatcta accagagatc tgatcttttt agttctctat cttattgggg tattctctat
    29701 cgtttattgg cgaaaacaga agaaggatcc ttccttgttc ttttacggca gtacgtggac
    29761 atttacggta atcttaactt attttgtcgt gttggaaatt ttttattcga ccttttattt
    29821 tttgattcca ttgttgttct ttagtatctt tgctttttct tatttcacag aaaaacgaag
    29881 gctgctgaat ggtcttttat tcaatgtttt cctcatcagt ttcggcatct acttgtttgt
    29941 cttgctgtat gaaacgcaaa atattttcct tggcggactg atcgccttga tcacgattcc
    30001 attgctactt gtccttttat ttggtattta tggattgatt gtttttcttt tttggaacgg
    30061 ggtcacagtt ttacgtagag aatcgcattc attagctaat cttttaacgt tgatactagc
    30121 catttttctt acactgtttc ttgtttttga ctttttcttg ttaaaatatt tgccgcaatg
    30181 gataaatgct ttgtttttct gcgttcccct gatcttgatc tatctattta tcgtattcta
    30241 caactttttg actgtctcat tcttgtatca gttcaaccgg cctcgataca atcaagactt
    30301 catcgttgtg ttaggcgctg ggttgatcaa tggagaaaca gtttctcctc ttctagccaa
    30361 gcgaatcaat aaggcaattg ctttttatcg ggctcaaagc cgtgctacat taaatccgcc
    30421 catcttattg atgtctggcg ggcaaggagc agacgaaaaa gtaccagagg ccattgcgat
    30481 gaaacaatat gccatggaac aaggaatccc tgaaagagac attcttgtcg aaaccaattc
    30541 gacaaccact ttggagaaca tgctctattc aaaggaaatc atggatcagc aaatgaaagg
    30601 gccataccgc gcgatcttta gttccaacaa ttaccacatt tttagagccg gtctttatgc
    30661 gtggcaagcc aaattgaaag caaatggtat tggtgcaaaa acagctttct actacttgcc
    30721 taatgcgttt ttaagagaat acatcgccat cttgatgatg aacaaaaaaa gacatatgat
    30781 catttgcgga ttgcttttcg caggctccgc attcttatcg ctgattactt tacttttcta
    30841 aaaaaacaag gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac
    30901 tattggcaaa aagagtatcc cttttttgac cgctacttgc tgggcagaat aaataccgct
    30961 gttgcctgaa cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga
    31021 accgaacaat tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa
    31081 tactccgata aagcccaatc ctgcaagaaa aggaacagaa acatgaagca aaggcgctag
    31141 tgctgcacca agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc
    31201 cgcgcctaaa gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg
    31261 tccattaaat gattcttgaa gtaacggaag actcaatccg agataacgtt gtgtttgcaa
    31321 aatcaatgct gctgccacaa ctacagctcc acctatcgta tttcgccaaa caggatgagg
    31381 aatccattgt gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat
    31441 caaaccaaaa gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg
    31501 aatcacaccc atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc
    31561 aaacagtgca gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa
    31621 cacttctaat ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc
    31681 actgattcca ctgataatca agatttcccg ttctgcttta tccaatcgga acaaacgtgc
    31741 tgtattatct gctaacgatc cccccatttg gactgctgtt ccttcacggc caacagaccc
    31801 cccaaataaa tgggtagtta tggttccaaa cagtgtaagt gtaataagcc gcaacgggat
    31861 tttttcttct ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagacc
    31921 gccgtgatac gcatagagat aagcaaaaag cgcaccacta actggtagta gataaaggag
    31981 ccaaggatgt gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga
    32041 caagctcccc atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatgtacac
    32101 taaaatgcgc attggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa
    32161 acgcctacta aagaaagggg ctgtccccag actttagtag gcgtcattag ctatctttcg
    32221 ttagcattta aaggcgaaca ccatcaccta ttcacttcca ttaaaagata gcatattttt
    32281 ctgtaaaaaa caataaaatt atcgttcttt ctttacacgt tcagcaaatt catagaaagg
    32341 agccaatttc gttaactgtt gattacattg gtcactatca tgacaaatat aattcccctt
    32401 tttcgtatac gtgccatcag aacctgcttt cgttgtagaa agaaaaagcg acacattcga
    32461 tgttttctga cagattgcac agattccctt atttatcgtt ggtgataaag taccgctaat
    32521 cccttttaat ttttcatctt cgtaatagac catgaatttt ttctgcgtac ctggatcatt
    32581 ccagccgatg tacgtatgtt cttgcaagtc gatttcattc caagctggtt gtttgagttt
    32641 ttttactttt cggaataatt tctcgatttg tggtttgcta ggctgcataa acggctgaac
    32701 gatttgcttc agcttctcca atgctctttc tgcttgcgct tttgtcagtt ttacgtctaa
    32761 aactgtcgtt aaaaatgtat cgatttctgg cagttcgtga tttaatatgt ctcgaatctt
    32821 ttcagctgct agtgcctgaa ctgtttgtac cgtttttgga tcattgacag atgagtacgc
    32881 atttaataac tgttctactt ctctttttat aaaaaaatat tggtatggtt ttattgtttg
    32941 ttccatgatt ttaaagtcct ttcttctaac caaagtgcat actttgtaga aaaaagtgat
    33001 cttctgcaaa gtatgtgtta cctgaagatc ccggactctt ttaaataaga tacgttttgc
    33061 atcttatcat cacccccttt aatgcttatt cttctatgta catgattcat tcgataaata
    33121 aaagtaaacc gtatcttgaa cagatagtca actgcaaaca gaaaaaagga ctgtgacaaa
    33181 agtcgtgtca aagtcccttg tttcgaatga atggtgttca aaagcttgca tctgcggtaa
    33241 taagccgaaa cttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    33301 aagctgacca cttctgtcac aacctcaata tggtctatta ttggttttac ctgttaaatc
    33361 gaggattctt tcccaaagta acgttgccat ctcttacgca tacttgcaga catgggctga
    33421 gccgcttctt tgactgcgca gtatttgtcc acgaatgtca caatatatcc ttctttatac
    33481 ttaggcggtg cgatcgttgc accccacatg tgcttcaaaa tgatatctcg ctcaagatcc
    33541 gacaaatcgg tgattttttc tgcattcttt acagcaattc ttggatggat atacgcatgt
    33601 gtcccctcgt caaatttcgt cgtacgccaa tcatagtaga acagatcatg caaaagtcca
    33661 gcacgcgctg ttgctttagc attgccaccc catttttttg cgagcagata actatagtaa
    33721 gaaacactga tggaatgctc caaacgagtg gaatgaacat gctgtgtgta attcgctaat
    33781 tttttcactg cttctgtttc taaaagatct tgtacataag acatatattc ttcgtcttca
    33841 cgccattttt ctgtcataat tatcgatctg ccaccttttt gaatttcatt ttcttctgaa
    33901 attgatctaa gtataccacc agtgttcgga ttattctagt cgctctagat aaaatagcta
    33961 aagcttaata gttccttaat cataaagaaa aatgataaag aacgatccct gctgcgactc
    34021 cgacattcaa tgattccgca tttcctttca ttgggatata tacgttctga tcagccgaag
    34081 acaagatttc ctgacttact ccctgacctt cgtttcccat gattatagcg aaatcctctg
    34141 ttttttctac tttgtctaat gcatgtgctt cttcatttaa ttctgtaccg tacaccgtaa
    34201 accctttgcc tttcattaca gggatcactt ctgccaaatc tttttgtaac acaggcaaat
    34261 gataattgct tccctgcatg cttcgcagca cctttgtact ataaatatct gccgttcctt
    34321 tacctaataa aacaccagcc ataccaaacg catctgccgt acggatcatc gttcccacat
    34381 ttccaggatc ctgtacatta tctagtaaaa gccagcctcc tgaaaaatct ggcgtatctt
    34441 cagatgttaa cgtcatcact gctaagatcc cttgcggtgt aggtagatct gacatagcgg
    34501 tcatgacctc atctgaaact agaaaagtag aaatctcttt gtttacagcc agccagtctc
    34561 cccattcttt catacctctc tgtgtcacaa aaagttcttt tatttctgca tcagacgacg
    34621 cagcttcttc gatcagatgg aacccttcca aaagatattc tgccttttct tctctgtatt
    34681 tctttttatg tagttttttt aattctttga ttcttggatt ttttactgat tggatctctt
    34741 tcacattcct cacctcaact gattatatca tggaataggt gcttgagctt gtttcatcct
    34801 aaaaaaatcg gtatcattga tttataaaac aggaaagaaa ggtgacgaac atgcgcaaag
    34861 ttaaaatgaa tgtccaagga cgtgtccagg gcgtgggatt tcgctatatg accaagatgg
    34921 ttgctgatca gttaggcgtg accggaacgg taaaaaacga agacgacggc tcagtcacaa
    34981 tcgaagcaat cggaaatgac gacatcatcc aaaaatttat cgaagaagtc aagaagtctc
    35041 cgagcccaag tggacgagtg cagtatgtgg atgtccaaga agatccgatg attgaggaac
    35101 gaaagaaatt tgatgtggtg ggataaggtt gtttttgaag cgctttgcct cgagtattaa
    35161 ggagaaacat tttccaaata gcttctcata ttttgaaatg taatgactta ataccgagag
    35221 gcagctgata aaacaccgtc aataaggttg tgaaaaagct ggtctgcatc aagcattaag
    35281 gactggttgt gaaaaatagc tctccatatt tttcaacagg ctggacttaa tgccgtagat
    35341 gcaagctttt gaacaccgtc gataaggttg cgaaaaagct gatctgcatc aagcattaag
    35401 gactagttgt gaaaaagtcg cttagttttg agtattaagg aaaattttgt gaaaatggct
    35461 ttccacattt ttgcataaat ttgacttaat accaagaaac tgacttttga acatcgtcga
    35521 taaggttgtt tttgaggcac tttgcctcaa gtattaaaga caggtagtaa aaaagctgat
    35581 ctataacttg caataaattt gcttaaccca tattttccag acagaacaaa aaagttttta
    35641 gttttttaaa taagaaagaa acacttggaa tcactctttt ctttctaagt atttctttct
    35701 tgattttttg tcttttttca aaatttttcg ctacgaaaaa gaacgaatat ttatatgaaa
    35761 tttctatgaa gttgattgaa ttccatgcgc ttttttagta tagttaagtt tgtgtaaaaa
    35821 ttatagaaga ggaagtattc tatgaataaa tggaaaaact ggttattggg atccggactt
    35881 gtcagtatcc tgctcttttt atctggctgt gtgcggatgg attcaaacgg aaaccctgac
    35941 acttcaggaa tcgtttatcg agtactcgtc catcctatgg gccaagcgat tacatatcta
    36001 gttgagaatt tcaattggtc ttacggctgg gcagttattg caatgactgt gatcgttcgt
    36061 atcatcatct tgccactagg tatcagtcaa tcgaaaaaaa caatgatcca atctgaaaaa
    36121 atgcaagcgt taaaaccaca agttgaagca gcacaacaaa agctaaaagc tgcaacaaca
    36181 cgtgaagaac aaatggcagc acaagcagaa atgcagcaag tatatcgcga aaatggattg
    36241 agtatgaccg gcggaatcgg ctgtctgcct ctattgatcc aaatgccgat cttctctgcc
    36301 ttgtatttta cggctcgcta cacagaaggt atccgtgaat catcttttta cggcatcgat
    36361 ctaggctcac caagtatggt gcttgtggcc atcgcagggg tcgcttatct gcttcaagga
    36421 tatatttcaa caatcggtat tcctgaagaa cagaaaaaga cgatgcgtac gatgctgatc
    36481 gtctctcctg ctatgatcgt cttcatgtcg atcagtgcgc cagccggtgt tacactttac
    36541 tgggtagtcg gtggtgtgtt cagctgtctg caaacattca tcacaaacgt tataatgaaa
    36601 ccgcgtttga aagcacaagt ggcagaagag ttgaaacaaa acccgccaaa acaagtcgtt
    36661 actccaagaa aagacgtgac agaatcagca aagccagctg acaacaaaca agcaacaaaa
    36721 caaatcaaac aaccaaaaaa cagtacaaac aacaaaggcc gcaacgcagg aaagcagcag
    36781 aagcggaaat aaaaatatat gacaaaaaac tgtagacaaa taaaaaaatt tctttgttct
    36841 acagtttttt tgttac
//
LOCUS       DAJSMK010000019        35768 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.019, whole genome shotgun sequence.
ACCESSION   DAJSMK010000019 DAJSMK010000000
VERSION     DAJSMK010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.019"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..189
                     /locus_tag="ON488_000955"
     CDS             <1..189
                     /locus_tag="ON488_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCR3231168.1"
                     /translation="NSNGILRRNGLPKSMDFREVNQTFISSVSNQRNYIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            326..1264
                     /locus_tag="ON488_000956"
     CDS             326..1264
                     /locus_tag="ON488_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HCR3231169.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            1279..2109
                     /locus_tag="ON488_000957"
     CDS             1279..2109
                     /locus_tag="ON488_000957"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HCR3231170.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLLVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            2153..3178
                     /locus_tag="ON488_000958"
     CDS             2153..3178
                     /locus_tag="ON488_000958"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HCR3231171.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNHYFRIYTNPDVVGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            3193..4131
                     /gene="galU"
                     /locus_tag="ON488_000959"
     CDS             3193..4131
                     /gene="galU"
                     /locus_tag="ON488_000959"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HCR3231172.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKIELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            4257..4697
                     /locus_tag="ON488_000960"
     CDS             4257..4697
                     /locus_tag="ON488_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HCR3231173.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIIRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            4700..5302
                     /locus_tag="ON488_000961"
     CDS             4700..5302
                     /locus_tag="ON488_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCR3231174.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSAELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(5364..6467)
                     /locus_tag="ON488_000962"
     CDS             complement(5364..6467)
                     /locus_tag="ON488_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HCR3231175.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGADSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVVWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            6677..7678
                     /gene="ccpA"
                     /locus_tag="ON488_000963"
     CDS             6677..7678
                     /gene="ccpA"
                     /locus_tag="ON488_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HCR3231176.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            8032..8427
                     /locus_tag="ON488_000964"
     CDS             8032..8427
                     /locus_tag="ON488_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231177.1"
                     /translation="MPKKRRKTIVIILTILAIGIGGKFYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGCYGALVTMTNNEGKSVYFDYFFSKQMNEISSY
                     GVENEEIQNEGVTTPKIRVIYSNGEAEEV"
     gene            8424..8678
                     /locus_tag="ON488_000965"
     CDS             8424..8678
                     /locus_tag="ON488_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231178.1"
                     /translation="MTVKDEEYRYISEHVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKDSLDGMQAMAAAPIVHSKLEKNFKNKKIPTNFRVLK"
     gene            8721..9116
                     /locus_tag="ON488_000966"
     CDS             8721..9116
                     /locus_tag="ON488_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231179.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGAYRMFVTMINNHDESVYFTFGFWKERNELGDY
                     GVENKSIQKEGITVNKIRVIFSNNKEEYI"
     gene            9116..10171
                     /locus_tag="ON488_000967"
     CDS             9116..10171
                     /locus_tag="ON488_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HCR3231180.1"
                     /translation="MMADKQYSVISEAVYWLDPKHRDYDHTYKENSIKKIDSYNFKIL
                     KIKDSLDGMQAMGVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRPG
                     ASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALYV
                     AAEKQWKNVGLNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEVR
                     ISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQEL
                     NNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELEK
                     KWHGKKACGKHVLSPLR"
     gene            10168..10374
                     /locus_tag="ON488_000968"
     CDS             10168..10374
                     /locus_tag="ON488_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231181.1"
                     /translation="MTEQEIIEALASVVATKENLVDSAKEVYLLRINKARRMGEAFDT
                     LVKEIQDKINEIVTRDRELAQQFN"
     gene            10386..10709
                     /locus_tag="ON488_000969"
     CDS             10386..10709
                     /locus_tag="ON488_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231182.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            10702..10968
                     /locus_tag="ON488_000970"
     CDS             10702..10968
                     /locus_tag="ON488_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231183.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNHQ
                     MTAEEAAQEFSNRHVHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(11131..13476)
                     /locus_tag="ON488_000971"
     CDS             complement(11131..13476)
                     /locus_tag="ON488_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HCR3231184.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKVIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            13755..14657
                     /locus_tag="ON488_000972"
     CDS             13755..14657
                     /locus_tag="ON488_000972"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HCR3231185.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEGGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQAFDPEVFPELLAEEVTL"
     gene            14868..16643
                     /locus_tag="ON488_000973"
     CDS             14868..16643
                     /locus_tag="ON488_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HCR3231186.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSRRKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(16953..18539)
                     /locus_tag="ON488_000974"
     CDS             complement(16953..18539)
                     /locus_tag="ON488_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HCR3231187.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            18790..19014
                     /locus_tag="ON488_000975"
     CDS             18790..19014
                     /locus_tag="ON488_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HCR3231188.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            19156..20907
                     /locus_tag="ON488_000976"
     CDS             19156..20907
                     /locus_tag="ON488_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3231189.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFVIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            20907..22691
                     /locus_tag="ON488_000977"
     CDS             20907..22691
                     /locus_tag="ON488_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231190.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQTITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            23148..23999
                     /locus_tag="ON488_000978"
     CDS             23148..23999
                     /locus_tag="ON488_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3231191.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSEQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGEKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            24095..25981
                     /locus_tag="ON488_000979"
     CDS             24095..25981
                     /locus_tag="ON488_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3231192.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIRAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILMMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGNLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKTSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFKSL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(26022..26924)
                     /locus_tag="ON488_000980"
     CDS             complement(26022..26924)
                     /locus_tag="ON488_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR3231193.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            27154..28557
                     /locus_tag="ON488_000981"
     CDS             27154..28557
                     /locus_tag="ON488_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCR3231194.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            28554..29990
                     /locus_tag="ON488_000982"
     CDS             28554..29990
                     /locus_tag="ON488_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HCR3231195.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            30135..31061
                     /gene="trxB"
                     /locus_tag="ON488_000983"
     CDS             30135..31061
                     /gene="trxB"
                     /locus_tag="ON488_000983"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HCR3231196.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            31275..33002
                     /locus_tag="ON488_000984"
     CDS             31275..33002
                     /locus_tag="ON488_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCR3231197.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIQKMTEE"
     gene            33018..33368
                     /locus_tag="ON488_000985"
     CDS             33018..33368
                     /locus_tag="ON488_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCR3231198.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(33463..34323)
                     /locus_tag="ON488_000986"
     CDS             complement(33463..34323)
                     /locus_tag="ON488_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HCR3231199.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            34415..34843
                     /locus_tag="ON488_000987"
     CDS             34415..34843
                     /locus_tag="ON488_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCR3231200.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            35005..35181
                     /locus_tag="ON488_000988"
     CDS             35005..35181
                     /locus_tag="ON488_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HCR3231201.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            35208..35654
                     /locus_tag="ON488_000989"
     CDS             35208..35654
                     /locus_tag="ON488_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HCR3231202.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT        11705 a         6346 c         7621 g        10096 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatggattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgtaatt atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata taattaagaa tgcgttttct attacattgg taattaaata
      241 aaaacgtttt ttttaattgg tagtactttt ggctagacaa tgataaaatg gtagagaaca
      301 ctctaataga aatgaggtag catgaatgtc agaagttgta aaagttagcc aattagtaaa
      361 aaaattatct ttggaaatcg tcacaggcga cgagaaaagt ttagaccgcg tcatcgtgac
      421 tggggacatc tcacgcccag gactagagtt gaccggttat tttaattatt attctcataa
      481 tcgtttacag ctatttggca gtaaagaaat cagttttgcg gaacggatga tcccagaaga
      541 gcgtttgatc atcatgagaa gattatgtag tgaagatatg cccgcattta ttatttcaag
      601 aggattgccg gctccggaag aaatgatcca agcagccaat gaaaatggga tagctgtgct
      661 gcgttcgcct atctcaacgt ctcggctgct aggtgaatta tctagttatt tagatgggcg
      721 cttagcccct cgaacaagtg tccacggtgt gttagtcgat gtctacggat taggtgtact
      781 aattcaaggg gacagtggga tagggaaaag tgaaacggcg ttggaactga ttaagcgcgg
      841 acatcgattg atcgcagacg atcgagtaga tgtctatcag caagatgaac tgacggtaat
      901 cggagaacct cctaaaatcc tggaacatct gattgagatt cgagggatcg ggatcataga
      961 tgtaatgaat cttttcggtg cgagtgcggt acgaggctct atgcaagtcc agttagctgt
     1021 ttatctagaa gcatgggcga aagataagaa atacgaccgt ttgggttctg aagacacgac
     1081 cgttgaaatc gcggaagtgg gcattccaca aataaaaatc cctgtcaaaa caggacgaaa
     1141 cgttgcaatc atcattgaag tagccgcgat gaatttccgc gcgcgtacaa tgggctttga
     1201 cgcaacgaaa acatttgaag aaagattaag tcgcttgatt gaagaaaact caggcaatga
     1261 ctagcaagga gtgacaatat gttagcacaa atcaatcgag ttgcttttga gcttgtagga
     1321 attcctatct actggtatgc attgattatc gtatcaggaa tcattattgc catgtggctc
     1381 agcagcagag aagctgttcg ggtaggatta aaagcagatg acgtgacaga ttttatgttg
     1441 tggggattgc cgatttccat tattggtgcc cgtttgtatt atgttttatt cgatcttccc
     1501 caatatatag ctgatccaat ccaaatattc aatatccgtt caggaggatt agcgatttac
     1561 gggggattga ttgcaggtgc aatcacactg tactttttta ccaaatatca ttttatttct
     1621 ttgtggacct ttttagatat cgctgcacca agtgtattac tggcgcaggc aatcggacga
     1681 tggggaaatt tcatgaacca cgaagcgtat ggtccagaca cgacacgaag tttcttagaa
     1741 agtctgcatt taccgcaatt catcattgat aacatgtata tcgaagggat ctatcgacaa
     1801 ccaacctttc tttatgaatc actttggagt ttgattggat ttattctgct tttggttttg
     1861 cggaagaaac cgcatctttt gaaaaaagga gaagtccttt tatgttatct aatgtggtat
     1921 agtttcggac gtttctttat cgaaggatta cgcacagaca gcctttactt tttaggtgtg
     1981 atccgcattt ctcaattatt gtctgctgtt ttacttgtcg gcacattgat tctgtttatt
     2041 tggcgtagaa aaaaaggaaa tttaccggat tatgaccgct cattaggaaa aaatcaacaa
     2101 attatttgat ttttagagcg ttaaaaatga aaaaaatttc aggagtggta aaatgaatta
     2161 tagagtagcg gttttaggac caggctcttg ggggactgct ttagcacaag tcctcgctga
     2221 aaacggacat gacgttcgga tttggggaca tcgtgcttca caagtagaag aaatcaacac
     2281 ccaacacacc aatcaacgtt atttaccaga tcatcatcta cccgattcca tccgagcatt
     2341 caccgatatg gaagatgcag taaaagatgc agatgcggta ctattcgtta tcccgacgaa
     2401 agcgatacgt tctgttgcaa aagaactagt tgccaaattg aatacgaagc cagtgatcat
     2461 ccacgcaagt aagggattag aacagggaac gcataaaaga atctctgaaa tcttgttaga
     2521 ggaaatcccg acagaaaaaa gaaaagctgt tgctgttctt tctgggccaa gccatgcgga
     2581 agaagtagca aagcatgaca ttacgacgat cacagcggca agcacagatg caaaagcagc
     2641 aaaatatgta caagagctgt tcatgaacca ttattttcga atctatacta accctgatgt
     2701 ggttggtgta gagatggggg cagctttgaa aaatattatt gccattggag ctggtgctat
     2761 tcacggctta gggtttggcg ataatgcaaa agcggcaatc atgacgcgcg gattagctga
     2821 gatcagccgt ttaggtgtag caatgggtgc caacccgctg acctttattg gcttaagcgg
     2881 agtaggcgat ctagtcgtta cttgcacaag tgttcattcc agaaactggc gcgcaggcaa
     2941 cttgttagga caaggacagc ctctagaaga ggtgctagcc aatatgggaa tggtcgttga
     3001 aggtgtgaat actactcaag cagcgatgga actagcccaa atgatggaaa tcgaaatgcc
     3061 catcactcaa acaatctatg aagtgctgta tgaacaaaaa gaaatcaaaa cagccgcaaa
     3121 agaaatcatg ttacgtgatg ggaaaaaaga aaatgaattc tcattaacaa ttttttgaag
     3181 gagcgaatgt atatgaaagt aaaaaaagca gttattccag cagcaggatt aggaacaaga
     3241 tttttaccag caacaaaggc gatggcaaag gaaatgttgc caatcgtgga caaaccaacg
     3301 atccaattca tcgttgaaga agcgttgaaa tcaggaatcg aagacatctt gatcgttaca
     3361 ggaaaagcta aacgaccaat cgaagatcac tttgattcaa atatcgaatt agaaacaaac
     3421 ctaagtgaaa aaggaaaaat cgaattattg aaattagtag aagaaacgac agatgtcaac
     3481 ttgcatttca tccgtcaatc tcatccaaag gggttaggac acgccgttct tcaagcaaga
     3541 gcctttattg gaaatgaacc gtttgtcgtt atgctaggcg atgatatcat ggaagacgaa
     3601 gtaccattga cacagcaatt gatcgatgac tatgaacgta cacacgcttc tacgattgcc
     3661 gttatgcaag ttcctcacga tgaaacttca aaatacggaa ttatcaaccc aggggaagta
     3721 ctggaagatg ggttatacaa tgtcaaaaac tttgttgaaa aaccagatcc aagcaaagca
     3781 ccaagtgatt tagctattat tgggcgttac ttattgactc cagaaatctt tgatgtatta
     3841 tcagaacaac aaccaggtgc tggaaatgag atccaactaa ctgacgcaat cgatacgttg
     3901 aataaaacac aacgcgtatt tgcccgtaaa ttcacaggta aacgttatga cgttggtgac
     3961 aaatttggtt ttatgaaaac aagtattgaa tatggtctga cacatccaga agtaggggca
     4021 cctttgcgtg aatacatcat gtctttaggt aaaacattag aagcagaagg aagcaagatc
     4081 gatcataatc caaaaggaat aacagaaatc aaagaagaaa agaaaaaata atcatttttt
     4141 tctaacgagc ttcagctgct aattgaataa aaagtagttg aagctcgttt ttatttgttt
     4201 aaaaaacacg aaaatgctat ccttatagaa aagagagaca agaagggagt ttgatcatgt
     4261 caggaggaga aattgcagga ttgatcgcag caatcgcctt tgcgatactt gtcgttttca
     4321 tcattcgcgt attgttgcaa gtttccaaaa ctttagaaaa agtagaccag actgtcgcag
     4381 aagcaaatac gacaattgag atcgtcacaa aagacgtaga tcttttatct agacaagtag
     4441 aaggcttgct ggtcaaaagt aatgagctgc tcttggatat caatggaaaa gtcgcaacga
     4501 tcgatccatt gttcacagca gttgctgatt taagtgaaag tgtatcggaa cttaatcatt
     4561 ctagtaaaaa catcgtgacg aaagtcggcg gaatcggaaa aacgacagct aaagcgactg
     4621 ttgccggaaa agtcggtgga acagcgatga aattttttaa aaacaaaaaa catactgaaa
     4681 cgacaggagg aaaataagaa tggctaaaaa aggtggattt ttattaggtg cagtagttgg
     4741 aggtacagcc gcagcaatcg ccgcattatt gttagcaccc aaatctggta aagaacttcg
     4801 ggatgaattg gctgctcaag cagatgattt gatggacatg gcttcagatt acacagatat
     4861 ggcaaaagaa aaatcagctg agttaacagg cattgcaaaa gaaaaagcgc aagatctttc
     4921 tcaacaagca ggggatctag caggtaatgt taagcaaaag gtaagtgaat cagcagagga
     4981 agcaggaagt gaatcagatg atatcttgtt aaacctcaaa gaacaatcag ctgatttatc
     5041 taatcgtttc aaaaaaacag cagaagatct gaaaaaacca gcagacgaat taggtagtat
     5101 tgctaaagat acttcagaag atatcatgat cgatgtaaaa gatgctgcag ataaagcagg
     5161 agagacggtc aatgaaggaa tgtcagaagc aaaaccagtt gcagatgaca caaaagaaat
     5221 gttgaaaatg gcaaaagaag atgcaaaaga agctaaaaaa gaaatgaaag atacaatgac
     5281 agattcgact accaatcact aagaatactc atttctagaa taaaaaggtg agagcggacc
     5341 agctcccacc ttttttattt tcattactct aaaacaagta attcttttgg tgtagtcgtg
     5401 aatggcacac aaccatcact tgtcacatac acacaatctt cgatacgtac ccctactttt
     5461 tcaggaatat agattcctgg ttcaagagag aagcacatcc cttcttcgat cactaagtcg
     5521 tttccttcta caagagaagg gaattcgtgg acggttgtcc caattccgtg acctaaacgg
     5581 tgattgaaat attcgccgta gccatagctg ttgattacgt ttcgtgcgat ttgatcaagt
     5641 tcacctgctg tcacacctgg gcgaactgcc tcttgtgcgg caagctgtgc ttcaagagtg
     5701 atgttgtaga ttttttcttg gaattctgtt ggtttttgat aagcaactgt acgagtagca
     5761 tcactgcaat agccattcca aacaacgcca agatcgaata acactagttc atttggtgaa
     5821 accttcgtgc ttcctggtgt accatgaggg cttgcagcat ttgctcctgc aaggactaag
     5881 gtgtcgaaag acatttgtga aacaccttgt ttttttaatt ggtattcgat ttctgcgata
     5941 attgcttgtt cagtcacgcc ttcttttact gttttgaagc caatttcaaa ggcaacatcg
     6001 gcccatttac cagcttcgat cagtttgtct ttttcttcta ccgtcttgat cagttgcaga
     6061 cgctggataa tagaagttag atcagtgtaa gaatctgcac ctgtcaagat atcagagata
     6121 gcatcgaagc gatcgacagt cagagcattc ttttcaatcc ctacattacc aggttgccca
     6181 tagcgtgcgc gaagctcttt tccgatgatc tcccaagggt tttcgctgtc taagtagcca
     6241 cgtacatcgt acgcccagct gctgttttga gcatcttcaa cttccagagc aggagtgaaa
     6301 aggaaaggat cttgttcaag agggataaaa agagctagta cacgctcgtg aggatcactt
     6361 tcatatccgg aaaagtaagc gatgtggcca gggtcgctga tataagccaa ttctacttgg
     6421 tgttgtgcca tccattgacg tagttcattg atttttacgt tattcatttg gcaacctact
     6481 ttctaaatta attttgtatt caataattgt accactgatt gattaaaaga ccaacgttct
     6541 taaaactgaa aaaagtaaaa attttcatga aaacagagat aaaacggttg caattgttga
     6601 gattatttga tatcctattt tagaaatgta agacgtattt tcagaaaaca tataaaatat
     6661 gaataggaga acacaaatgg aaaagcaaac aatcactatc tatgatgtag cgagagaggc
     6721 aaatgtttcg atggctactg tttcacgtgt cgtaaatggc aatccaaacg tcaaaccagc
     6781 aacaagaaaa aaagtcttgg aagttatcga tcgcttggat tatcgtccaa atgcagtcgc
     6841 acgtggcttg gcaagtaaga aaacaacaac tgttggggta atcattcctg atgtcagcaa
     6901 tatgttcttt gcctctttag cacgtggtat cgacgatgta gcaacaatgt acaaatacaa
     6961 tatcatctta gcaaactcag atggcaacga tcaaaaagaa gtcaatgtat tgaataattt
     7021 attggctaag caagtggacg gcgtgatctt tatgggtcac catatcacag acgaaatccg
     7081 tggagaattt tcacgttcaa aaacacctgt tgtactagct ggttccattg atccagatga
     7141 acaagtaggt agcgtaaaca ttgattatgt atcagcaaca aaagatgcag taaataaatt
     7201 agcaaaaagc ggcaataaaa aaattgcttt tgtcagcggt gcgctgattg atcctatcaa
     7261 tggtcaaaac cgtctaaaag gctataaaga agcattaagc gaaaacaatc taccatatag
     7321 cgaaggatta atctttgagg cacaatacaa ctttaaagat ggtctgtctc tagttgaccg
     7381 gatccataat agcggtgcaa cagctgtcta tgtttcagac gatgaattag ccattggtat
     7441 cttggatggt ttattagacc gtggcgtaaa agtaccagaa gaattcgaaa tcatcacaag
     7501 caacaattct ttactgacag aagtagctcg tcctcgtttg acaagtatca cacaaccatt
     7561 atacgattta ggagcggtat ccatgcgcct attgacgaaa atgatgaata aagaagaagt
     7621 cgaagaaaaa acgattatct tgccttatgg aatcgaagaa aaaggatcaa ctaaataata
     7681 aaagatcaat catttagagg ttgttccaaa agtggccaac ttctggaaca acgtttattc
     7741 gagaaaaggg gttatgacaa aattttgtca taaccccttt tttttgtgac tttaaaaaaa
     7801 gagaaaatgg cggaaacaaa ccttacgtcc atcgtatacg acacaatctg tgcgtagatg
     7861 ctacattttg ttcactacta tcaaaattac tttaaaatga aaacgtgata aaaaagaaag
     7921 tagaaaagta gaaaagtaac tctaaaaaat ccaaaaaaat ccaggctcga ttgcgtactt
     7981 atcttaaagg agaaacaatc catcatacat aacccgaaag gagacttcta tttgcctaag
     8041 aaaagacgaa agaccatagt catcattttg accattcttg ctataggaat cggaggaaaa
     8101 ttttacatgg acaaaagaga agcacaaaga cagaaagatt tactcgcagt agaaaaacaa
     8161 tccgtcaaag ttctgaaaaa tacctttgca gatatcaggg aagtgaaggt agaagaattt
     8221 aaaaaaaacc ctgttactgg atgttatggt gcacttgtga caatgacaaa taatgaaggg
     8281 aaatctgttt attttgatta ttttttttca aaacaaatga atgaaattag cagttatggt
     8341 gtagaaaatg aagaaataca aaacgaaggg gttactactc ctaaaataag agttatttat
     8401 tctaatggag aggcggagga agtgtgacag taaaagacga agagtataga tatataagtg
     8461 aacatgttta ttggctagat ccaaaacatc ctcaatatag taaaagttac aaagaaggcg
     8521 ccattaaaaa ctttggagaa acaaaattcc aaatcctaaa aatcaaagac tcattggatg
     8581 gcatgcaggc gatggctgca gcgccaatcg tccatagcaa attggagaaa aatttcaaaa
     8641 ataaaaaaat tcctacaaac tttcgcgtac ttaaataatg aaggtatcaa tacttacata
     8701 aaaagaaagg aggcacgttc ttgtctcgga aaataagaaa actcagctta gccattttat
     8761 taatcgtcat attaggaatc ggagggaaag tctatatgga caaaagagaa gcacaaagac
     8821 agaaagattt actcgcagta gaaaaacagt cagtcaaagt tttgaaaaat acttttgcgg
     8881 atatcaagga agtgaagatt gaaaaatctg ctcgaaatga aatgacggga gcatatcgta
     8941 tgtttgtgac aatgataaat aatcacgatg agtctgttta ttttacgttt ggattttgga
     9001 aagaacgaaa tgaattagga gattatggcg tagaaaataa aagtatacaa aaagagggga
     9061 ttacagtaaa taaaatcaga gtaatttttt ctaataataa ggaggaatat atttaatgat
     9121 ggcagacaaa caatacagtg ttattagtga ggctgtttac tggctagatc ctaaacacag
     9181 agactatgat catacttata aagaaaattc tattaaaaaa attgatagtt ataattttaa
     9241 aatcctaaaa atcaaagact cattggacgg catgcaggcg atgggtgtag cgccaatcaa
     9301 gaacggtaaa gtggatcttt ctcaagtagt gattgctttt gcaggaacga acttaagtga
     9361 ttggaaagat ttggaaacgg atgcaaggag tatcatgaat ctctatggga atagaccagg
     9421 agcaagtttt tctgaaaaag caacaacaaa caagatttta tccgttagtg gattgaaaac
     9481 agcggggcaa atcaattcag cgattgcatt tgctaatgaa gtaaaaaagg aatatggaga
     9541 agctgctatt tctactaccg gccattcatt aggtggattc ttagcattat atgtagcagc
     9601 agagaaacaa tggaaaaatg tcggcttaaa cgggccggac ccgtatgatc tcttatcacc
     9661 agaagcaaaa aaatgggtgg aagaaaatcc cggtatgctc accaattacc gaaatcacgc
     9721 cgattttatc ggtaattttg gtggtaatgg cacaggtgct gaagttcgga tcagtatgga
     9781 aacagcattc ttgaatctgc ttgcttccca cagtttaacc tcttggaagt ttgatgaaaa
     9841 tggaaagctg attattcctg aaaatgaaaa taatgttaaa gctcgaaaac aacagaaaga
     9901 aaaccaagcg acccagttgt tttcctatca gttgcaagaa ctgaacaaca tacgtaaaaa
     9961 actacgatta agtggcggcc ggctgacagt taatgaacaa atttacttag atgacacaca
    10021 agctaggtta gtagtggaaa agttatcagc aaaaatgaaa agcgctatgg aagaagttat
    10081 ccgcatcaat caaagaggaa tttttgagct agagaaaaaa tggcatggca agaaggcttg
    10141 cggcaagcac gtgttgtcgc cccttcgttg actgaacagg aaatcataga agcattagct
    10201 agtgttgtcg ccacaaaaga gaacttagtc gattctgcga aagaagtcta tctgctgcga
    10261 atcaataagg caagacgtat gggggaggcc tttgatacat tggtgaagga gatccaagac
    10321 aaaatcaatg aaatcgtgac acgagatcga gaattagcac agcaattcaa ttaaaggaga
    10381 agtagatgaa actagaagaa ttggaaagag attatcgaag tgaacgaaga caattagaag
    10441 ctcaagaaga tgaattgatc cactttaaga atcaaggatt acgattgatg gagcaagagg
    10501 agcagcgact gcatcatgta ttaaagaact tagctttaga taatgagcct ctgtttcaag
    10561 caagacgaag ttattcgaat tatcaggagc attatcaaca agccctacaa gtagaacgac
    10621 gaaaactcta tcagcagcaa gacgaactag aacgttccta tcgtcaaaaa atcagacaaa
    10681 taactatgga gaaatcatct tatgaatgaa tttttaatgc aattactaaa agaattagag
    10741 aaaaatctac atcgatcaaa tgtacgttca gttggtatgg ggatatctca gcaaatttgg
    10801 gcagaaaaac gattgacaga tcaaaaccac caaatgactg cagaagaagc tgctcaagaa
    10861 ttttctaacc gacatgtaca cttgaaagaa tcagtaaaag ggcaatttgc agaaaaacta
    10921 accgaattat tccaaagaca agaaaagaaa ttaaaacagt ttcgttagta aagttatata
    10981 gaaaaatttt gtgaaaatgg cttttcacat ttttacataa atttgtctta atatcgtaga
    11041 tgcaagcttt tgaacaccat ttattcggaa aaagggagct gtgacaagat ttttgtcgca
    11101 gctcccttta attctgatta atctattaga tcaatcatct ttatcgtctg attctttggt
    11161 ctctggattc gctctagcat aagctgaagc ggtgttccag taatctgtat agttttcatc
    11221 agtaccgcca acgccgaatt taaaggcgct tttcttcgga ccattttttg cccaaagtga
    11281 ttccactgtt tttcctggcg tttggataga ttttttattg acagtaactt ttccagctgt
    11341 ttgtcctgtg aacccagata cttttttctt catcacatca gatgataagt caaatttctc
    11401 atcagtgccg aaaatctcag ggtttgcttg gtaagcttga ttgattagat tggcaagata
    11461 attagccgaa cgtatccttg cttggctgtc cattccagta ttgtcatcgt gtcctgccca
    11521 gctactgata gtgatagacg gagtagagac gatcagccat gaatctctgt attcgttggt
    11581 agaaccagtt tttccgaccc aatctgcttt tcctagattt ccgtttaagc ttgaaatgac
    11641 atctttgaat ggtgtagtga ttttttcatt gatcacactg cgcatcatgt cattcatgat
    11701 cgaggccgtt gcttcggaat aaatacggac agaattactt tcatgtttat aaatcacatt
    11761 acctgcatta tctgtgatgg aatcaatgat atagccttct tcgtagacgc caccattagc
    11821 taaggcctgg aatccatttg tctgttgaag cgtcgttaca tctactgtcc ctaaaggagc
    11881 agattcaacg ccccaattat catttgctgg gtagttcatc ttcgccaagt agtgctcgta
    11941 agcatattgt ttcgatccac ccgaattcaa tacgtcttgg tataagtgat aagctgggat
    12001 attgttggac cattccagtg actcacggac ggtttggaag gtgttcgacc cttcattggt
    12061 cgcattgacg attttctcgc cagcattttc tccttcttgc caagtcgttg cataatctga
    12121 tacacgggat tctgatccga caagtcccat atcgattgca ggaccgtaaa caagaaccgg
    12181 tttgatggat gaaccagctt gacgttctgt atcaaaggcg tggttatttt gattctggct
    12241 gtaattccgg ccacccacga atccatagat acgtccagtc ctattgtcca tcaatacatt
    12301 tccagtctcc acttggctac cagcaccatc atctaacata tagccgtaat tttctacgcc
    12361 ggtttgcaat gcagcataga tatctttatc gatcgtcgaa tggatcgtat atcctttgtt
    12421 ttggatcgtt tgctgtgctt tttgataata agcttcactg accgatgaat ctgacatatc
    12481 agcattatct ttttctgcca attgttgtgc aataatcctt gttgcttcgt tcatcacggt
    12541 ataatacaag aattctctgt cagtctgttc cgcgatttgt tgtgggagaa agtcttttgt
    12601 aagatcatag gctttcgctt cttcgtattg ttctttcgta atttgtcctt cacggtacat
    12661 actgaataaa acaaaatctt ttctggcaag accggcagaa agatcttctt ttagcgcgcc
    12721 tgtattcgtg tagggactat acgtgatagg gctttgaggc aaaccagcga tataagcagc
    12781 ttgtggcaga gtcacatctt ttgcatctac accaaagatt cctcttgcag cttcctggac
    12841 tccagcaata ttttgcccct tattattccg accaaatggc gagacattca aatacgtagc
    12901 aatgatctca tcttttgaaa agtatttttc tacttgtgca gaaagaacga tctcgtttgc
    12961 tttacgtttg aatgttgttt catcggttag gatctgctgt ttgactaatt gctgtgtcaa
    13021 agtggatcct ccagacgagc cgatgccagt agcttctgaa actaatgctc gtaaaacagc
    13081 tttagggaca taaccttggt gtttatcgaa gtattcatct tctgtactga taatcgcggt
    13141 tttcaataaa ggcgaaatct tatcagatga aatagtcgtc cgcatcagat ctgtctggat
    13201 ttttgatatc tctgtattat ctgcataaac aatctttgac gtttccgtaa tgtttcctag
    13261 ttctgtctgc agttcttttt tagtcggcaa ttgtgtgtct tcgacaagat aggcaaagta
    13321 gccagcacct attccgatac ctagagctgc gaacaacaaa agaagaacag taataaaaac
    13381 agtcaatgat tgaaacactc taaaaataac cttaggaaca aaccattttt ctttttttct
    13441 tctattctgt ttttttcgag tatttttgcg tggcaaaagg gtcacctcaa ctaatggttt
    13501 tatttcgcta attatagcaa ataataagac aaaaaaacag acaaggctgt ttttgacagg
    13561 aatttctttt tcgaatgaga taaaacgtga ggaaatgatc ttttttatga aagagttctt
    13621 aagcttttct ttagagaaag tttcagttac tatggagaac agggcaaaga aaaacaaacc
    13681 attttctttg tacatcatct taccaatata taggaattgt tcgaaacaat tgcctttcaa
    13741 ggaggaatcc atccatgtta ttaggctcac acgtcagcat gagcggaaag aaaatgctgt
    13801 taggcgcggc agaagaagca gccagttacg gatcttcgac ctttatgatc tatacaggcg
    13861 ctcctcaaaa tactagaaga aaagctatcg aagagatgaa tattgatgcc ggaaaagcat
    13921 ttatggcaga aaacggacta acaaatatcg tcgttcatgc gccctatatc attaatttgg
    13981 gaaatacgat caaaccagaa atgtttccat ttgctgtaca atttctgaga gaagagattg
    14041 ttcgtgcgga agctttaggt gctactcaaa tcacccttca cccaggcgct catgtaggag
    14101 caggggcaga aggtgggatt gctagaatta ttgagggttt gaatgaagtt ttgacaaaag
    14161 aacagacggc acagatcgct ttggagacga tggcagggaa aggtacggaa atcggtcgaa
    14221 catttgagga actagcgcaa atcatcgatg gagtaaaatt gaatgaaaaa ttatccgtta
    14281 cttttgatac atgtcatacg aatgatgccg gatataatat aaaagaagat ttctcaggtg
    14341 tgatggaaga gtttgataag gtcatcggat tagatcggct taaagtactc catatcaacg
    14401 attctaaaaa tccacaaggt tctcataaag atcggcatgc caatatcggt tttggaacaa
    14461 ttggatttga cacattgaac aaaatcgtcc atgatccaat gtttgacaac atttcgaaaa
    14521 tcttagaaac tccatatgtc ggtaaagata aaaagaaagc ttacgcacca tatggaaaag
    14581 aaattgccat gttcaaagcg caagcattcg atcccgaagt gtttcctgag ttattagcag
    14641 aagaagtcac actttaagtt ttctatctga cagcaacaaa aaaggattgg gcagtctgcc
    14701 ttgtcctttt ttgtttaaga aacaaaggag tgctttttgc agtcgttttc gccatgctcc
    14761 tttcgccccc tctttttaaa ttcagacaaa cagggtatac tgatagaaaa gtaaaaaacg
    14821 aaaagattca caagcaagta gcaaaacgtg attgaaagga cgaaaagatg ctgaacactt
    14881 taaaaccctt gatcaaccaa ctaaaaaaga aacatacata ctttattctt ggcatagccg
    14941 tattatttac aattattcgg ttgtatttat atagtaaagc aatctatgga acagatatgt
    15001 cggcaaccta tgatgatcag ctgctgattc actatgctca aaatattttg gatggtaaat
    15061 ggctagggga gtacacgact acgacacttt caaaagggat ctcctacagc ttgtttttag
    15121 tacttgcaca taaactgcat ctttcttatg cagttttgtt cggcatgttc agtattcttg
    15181 ccagcatatt ggttgcacta gcgtttaaac cgatcgtgaa gaacaagtat cttcttttaa
    15241 gtatctattt ttattttttg ttttctccga ttagttttac acatgagtat tccactcgaa
    15301 cgtatcgtaa tgctctcgtg atcccggctg ttgagatcat tatcgcttgt ttactagcta
    15361 tttattaccg taaatatagt tcccgcagaa aattgctgcc gtggttttta gggttagctg
    15421 tttcttttcc tttcttttgg ttcattcgcg aagattccat ctggcttctt ccttttactg
    15481 tagtcgcgtt aggcatcagt ttcgttcaga tcttgctagg acaagacttt tctttcaaag
    15541 aagcaaagaa gttaaaagaa cgaccatttc tcctttcgaa acaagaatgg ctgaaacttt
    15601 cattgttttt actccctcta gtcggtttct ccatcgtcta tcagtggatc gaatataaaa
    15661 acgagacaac atatggtatt gccaccatca atgaccgttc gagtggtgaa tttggacgtt
    15721 tgatgaaaca gctgatccga atagatgacg aaacgaactt aaataaagaa aacagtgaga
    15781 tatgggtctc gcatgctgca ttaaataaag cattagacgc atctcctaca tttcatactg
    15841 tttctactcg tattgacgaa ttgtatacga ctcatgcgtg gacccaaggc ggaaaagtaa
    15901 aagaattacc aggagatatc attttttggg cattgcgaga tgtggtaagc gaatctggtt
    15961 attaccaaaa caatgcaaaa gaaaccaatg atttttggaa aaaagtcaat caagaattag
    16021 aagaagccta tcaaaaggga actatcaaaa agaaaaaaga attctatctg atgggatcag
    16081 gggatggaaa gacgatgaat gatctgccaa tcgtatttgc ttttctgaaa tcaggatatg
    16141 cctatgcatg gcgatacaaa gatttccatc aaggagggaa ttatagtttc gggacgcaag
    16201 aacaagtcga acaggcccaa gaattattga atcttccact aatggataat tggatcgata
    16261 gcagtgatcc gagaacacct gatttccagt tgacaaaaac agcaaaagtc gcgaatgtca
    16321 tgataaaaat ttaccaagtt ctggccattc ccgtgctgat tgcttcaata gcagggatat
    16381 tacttatgat actaggaacc gtatttgcaa aagctgatcg tgcctattat agttcctctt
    16441 tgattgtagt caccggatta atactgacac aattggtttt tcttttcggt gtctcgtggt
    16501 tttgttctta tgcgccagaa aaaaaggatt attttttaag tgtctacact ggcgcaggcg
    16561 tgccattaac acaattcatc gtagtaacaa gcatgctagt tttcagtaaa ttgaatctga
    16621 aaaaagcttt atcttctaaa taaaaaggga actgtgacaa aagtcttgtc gcagttcctt
    16681 tttccgaata aacggtgttc aaaagcttgc atctgcggta ataagctcaa ccaaacgtaa
    16741 aatatgagga actatttttg tttggctgtt cttattactt gatgcaggac agctttttca
    16801 caacctctga tacacggtgt tccagaagta acttcttcga aaaataagcc gaaatttcac
    16861 aaaaatttga aaagcaattt tcttaaattc cttcttattt cttgaagctg cccacttctg
    16921 tcacaacctc ctttgtgtaa aagaatcagt ttctattcga tttcttctat cgtttcttgc
    16981 aaacgctgtt catatttttt gtttccttta tataaatcac caatcgtcca tgccaacagg
    17041 agaaggacaa gaacaatgat tacataagcg atttgatcag ccaatgctag ttgagctgag
    17101 gtggcttgct cgccgaagaa actttcgatt tgacctggta atcctcgtaa gttcaagtaa
    17161 gtcagactaa tcacagagaa ccagccaagt agttttacaa caaatgaatt tttgaatcgg
    17221 ctccccatct ccgcttggct attggtcatc atcagtaaag gaatcatcga gaatggcaat
    17281 gcaaaagcca gaaaaacttg ggattcattc atcaagttat tcaaagcggt atgttcttcg
    17341 atcgttcctt ttgtacttgt aaacaaaaca caaatcaata caggaatcac agaaagcaat
    17401 cgtgtgacta gtcttcttag ccaaatcggg atacgcatat ggatgaagcc ttccatgatg
    17461 acttgaccgg tcaacgtacc agtaatagta gagttctggc cagaagcaag aagtgctaca
    17521 gcaaataaag tggacaagat accagatttt gcgacagcaa tcaagatacc attgctcata
    17581 gctgatggat cagataaagc ttcatacaga ccaaaaaagg aaggatcttg gacagaaccg
    17641 gttttgaata cagcgacacc catgatcaat agcagtgcat tgactagaaa agccattgac
    17701 aactggatat tagaatccca agtagaaaag cgtaccgctt gtgctacatc ttcttcatct
    17761 tggtgatcga tcttccgagt ttgagaaact gctgaatgaa gatataagtt atgcggcatg
    17821 actgttgcac caataatccc taaagctcca gtcagcggag tttcaccgcc gatgaccggt
    17881 gagtctgaga atgtatgact gttagggata aagccggcaa acaaactgtg ccaatcaggg
    17941 ttagacaagc caacttgata gacgaaaacg aataaaatga cgaaaatcaa gcagacaacc
    18001 aaagcttcga ttttacgaaa cccgactttt gtcagcaata agaggacgaa aacatctaac
    18061 acagtgataa atacggcaat cactaatgga atatcaaaaa gcaggtagag ggcgattgct
    18121 gcaccaatga cttctgcgat gtctgttgcc ataatggcta attcagtcaa gatccataaa
    18181 atgacaccca atgtcttact tgtccgtgct cggattgctt gggccaaatc catttgggtc
    18241 acgattccta attttgctgc catatattgt aaaagcatag caatcagact agacatcaaa
    18301 ataactgaca tcaataaata ttggaaattt tgtccaccag tgatcgaagt ggaccagtta
    18361 cctggatcca tataacccac tgctactaat gcacctggtc cagagtaagc aagaagtgtt
    18421 ttaaaaaaac tttttccctt gggtacatcc actgttccat ttacttcagc taaagataaa
    18481 ccatttgtat gttcaataag tcgatgctta tgaaattgtt tgttggattg attattcaag
    18541 aaaaaaccac ctttcctatt tatctacgat tacattctac acctcagaaa gaaaaaatta
    18601 aagaaaaata ttcggtatgc ctaatttttt ttcgtggcgt gtcttgctgg ttaatgaaag
    18661 aaattttgtt cttctctaaa aaaaccacta ttttttgcat gaaactaaag aatacgcctt
    18721 tcttttttca ataaacttta gtaaaataaa tcattgagag caattcggaa atagaaagga
    18781 gagatttata tggtatcaac aggtattgtc gtacttattg ctattattgc tttgctaatc
    18841 ggcgcagtag gtggcttttt cctagcgcgt aaatatatga aagactattt agaaaaaaat
    18901 cctcccgtta atgaggacat gttgcgatca atgatgatgt caatggggca aaaaccatct
    18961 gagaagaaaa ttcgccagat gatgcagcaa atgaagaacc aagggaaaaa ataggttctg
    19021 acccaaagac tttttgcggg ctgatttttt cagtccgttt tttatttcgt aatttgttag
    19081 actattcaga ctattcagca aaaaagacaa gcacagacaa tcctatgctc ttgataaaga
    19141 caaaggagga gtaaaatgtc gatttttaga aaattaggtt ggttttttcg acaggaaaag
    19201 aaacattatt taattgggat tttctcccta ttcgcagtgg ccttggtaca gttagttcct
    19261 ccaaaggtga ttgggatcat cattgatgag attgccgata aaaatttatc aataaagatc
    19321 atttcctggt ggatcttatt attgatcctt gcagctctct tacaatatct ttttcgttat
    19381 atctggcgga cgaatatttg gggaagtgca gctcggttgg agaaagaact tcggcagcag
    19441 ctattcaaac attttacaga aatggacaat ctcttttacc aaaaatatcg gactggagat
    19501 ttgatggctc atgcaacgaa tgatttgaat gcaatccaaa atgtagcagg agctggtatc
    19561 ttgacctttg cagattcagt gatcacgggc ggaacaacga tcattgcgat gattttgttt
    19621 attgattggc gcttaacact gattgcgctg attcctctgc ctttactagc cgttacttca
    19681 cgagtgctgg ggtcaaaact ccacgatgct tttcgtgatt cgcaagaagc tttttctagt
    19741 atcaatgata agacacaaga aagtattact ggaatcaaag tcattaaaac atttggacaa
    19801 gaaaaagaag atctcgcgga ttttgaagaa aagattgaag atgcaattat taaaaacaaa
    19861 cgagtcaatt ttttagactc cttatttgat ccattcatta ccttgattat cggtctgtct
    19921 tatgttgcaa caattatttt aggtggaaag tatgtcttgg aaggcacgat ctcgatcggg
    19981 cagatggtct catttattag ctatatcggt atgcttgttt ggccgatgtt tgcgattggt
    20041 cgattgttca acgtattgga aagaggaaat gcttcttatg atcgcgtcaa tgaacttttg
    20101 catgaaaaga cgcatatcgt ggaacaactg ggtgcagtgc agaccccggc aaaaggcgag
    20161 ctgaatgtag ctatttcctc ttttaactat ccgaaagaag aatcaccagc attagaacaa
    20221 atcaaatttg tgatccaaga aggagaaaca ttaggtattg ttgggaaaac tggtgcggga
    20281 aaaacgacga tcatcaaatt actgatgcgt gaatacgatg attatcaagg aaaaatccaa
    20341 tttggcggac gttcgatcaa agaatattca ttgaatgctt tattaggatc aatcggctat
    20401 gtgcctcaag atcacttctt gttttcgatg accattcgag ataatatccg tttttctaat
    20461 ccaaaacttt cagaagaaga agtagagcat gcggcttctt tagcatttat caacaatgaa
    20521 atcaaggaat tgccaaaagg ttatgatacc ttagttggag aacgtggagt ctctttatct
    20581 ggcggacaga aacaaaggat ttcgattgct cgagcattga tcaaaaatcc tgaattgctg
    20641 atcttagatg atgcactttc tgcagtagat gccaaaacag aagaagctat cttgcataat
    20701 ttaaaagaaa taagaaaaga gaaaacaacc atcattgcag ctcaccgttt aagcagcgtg
    20761 atgcatgcaa aagaaatcat tgttgtcgat caagggaaaa tcattgaacg aggaacccat
    20821 catgagctgc ttgcattagg cggctggtat gaacgaatgt gggagaaaca gcaattagaa
    20881 gcgaagatag aaggaggcga ggcctgatgg atgaaaatta tcaatcggaa tggacaaaat
    20941 cgattccact taaagaacag aagaagatca tcaaacgact gatgaagttc gccaaacctt
    21001 ttagaagaac gttcatcgtt gctatcttat ttgcgtttgc tctgtctgtg atcaatgtcc
    21061 tattgccaag gatcatccaa acttttatgg atgatcatct ggctaaacag tcggctacga
    21121 cacaagttat tttgtttttt gctggtatgt acttgtttgg agtcatagtc aaaagtatca
    21181 tttggttttt ccaatggtat ttgtattcca tggcttcatt gaagacctat cagtatgttc
    21241 gggtaagatt atttgaaaag ctgcatacac taggtatgcg ttattttgat cagacaccgg
    21301 caggatcgac cgtttctcga gtgacaaatg acacagaaac gctatttgaa ttttggtatg
    21361 tctttttgat ggtattgact gggatctttg cagtcgtttc ttccttcatt gccatgtttc
    21421 aaatcaatgg agaaattgcc ttgtggactt tggtgttctt gccgatttta ggaatcgtca
    21481 tctggtatta ccagaaattc agttctcgta tttaccggaa tatgcgggaa aaattaagtc
    21541 agctgaacac gaaattgaat gaatcgattt ccggcatgcg tattatccag cagtttcgcc
    21601 aagaagctcg tttagctaaa gaatttgaac aagtgaacaa cgagtattta gacacgcgct
    21661 atgcgatgat caaaacgaat tcgattctgt taagtccgat catcaatttt ctatatgcat
    21721 tggcgattgc gttggcgttg actttgtttg ggatcgatgc gctgcattct cccgtagaag
    21781 ttggactgat ctatgcattt acgacctatg tccagggatt ttttaatcca atgtctcaaa
    21841 tgatggactt tttgagcacc tttacagatg gaatggttgc cggtagtcgt attttgaaaa
    21901 tcatggatac agaagaatat gcaccgcaac aaaatcctgg agcagatcaa acgattactt
    21961 caggtaagat cgagtttcgc aatgtaagct tttcttatga tggagagcac aatgtattga
    22021 acaatatctc ttttgtcgct aatccgggag agaccgttgc attagtgggg cacaccggaa
    22081 gcggaaaaag ctcgatcatc aacgtattga tgcggtttta cgaattttat gaaggccaga
    22141 tcttgattga tgatcatgac attcgagaat atccaatgga agagttacgt aagaaaatgg
    22201 gattggtctt gcaagatgcc ttcttgtttt atggagatat cgcaggaaat atccggatga
    22261 tgaatccaac tatcacagac gaacagattc gccatgcagc tgagtttgtt caagcaaaca
    22321 agttcatcga tgaattacca aaaggatatc actcaaaagt gatcgaacac ggtgccagct
    22381 attctagcgg acaacgacag ctgatcactt ttgcgcgaac aatcgtgaca gatcctaaaa
    22441 tactagtatt ggatgaagcg acagcaaata tcgatactga aacagaagga ttgatccaag
    22501 aaggattgac aaaaatgcga caaggacgga caacgattgc gattgcccat cggctgtcca
    22561 cgattcggga tgcagaattg attttagttt tagacaaagg tcatatagta gaacgcggga
    22621 atcatgaaac acttctagcg caaaatggtt tgtatgcaga tatgtacaaa ctgcaaagca
    22681 gtggtgtgta aaaagtggtt gtgacagggc tccgttcagc tttaggtgat aagaaaaaaa
    22741 ttgtaaaaaa ggctttccag atttttgcat aaatttggct tatcaccgat aagctgatac
    22801 tggaacaccg tatattagaa gttgggacag tagcatagta gcattttgac ctaagcgcta
    22861 gagtgaaaat aaaacagagc ttcccagatt cttcatctgt gagcggtagt gtcgtagtca
    22921 ccagatttaa aaaagattcg acagctagtc agaagtgcct aatagccact aagaaagcgt
    22981 tgacaaaagc gcttgctttc gataatataa agaaaacgat acaacttgga tagtgattgc
    23041 ctgatgcaag ctaaacctga tgagtctccc atggttccat ggacggcttt ttgggttttt
    23101 ctttttgttt tggatacagc cctatatatc atggaaagga gtaaaacatg ctgattgaga
    23161 aagtactgaa taacaacgtc gtaataacca gagatgaaag aaatcaggaa atgatcgtga
    23221 tgggaaaagg tttggcattc aaaaagaaag tgggtgaccc gatttttgac tcatgcatcg
    23281 acaaaaaatt tcagttgaca aatgacggac tttcagaaca gttccaagaa ttggcacaag
    23341 cgattcctct tgagtactta gaaatttctt gtgaaatcat tgaatataca aaagaggctc
    23401 tacaagtcca gttgaatgat tcagtgtata ttgcattgac ggatcatttg tatacggcta
    23461 tcgaacgtca caaaatggga atatttgtac caaatgtatt gctgtatgat atcaaacaac
    23521 tatttcctaa agagtatgcc atcggggaaa aaacagtgaa gaaaatctcg gataaatacc
    23581 acatcaagtt atcagaagat gaagccggat ttatcgcatt gcatttagtc aatgcacaag
    23641 gcattcaaag ccaacaagac aatacctacc tgtttactac aacaatacag gatattctaa
    23701 atatcgtccg ctattactat aagattacat ttgatgaaga ttcagtccat ttttttcgat
    23761 tcgtcacaca cctacgtttt tttctgacac gcgtcctaga tggagaaaaa tcagaagtgg
    23821 gagaagtttc tgaggaattg taccaagtta ttcaaaaaaa atataaggat acgtttggtt
    23881 gcgttgagaa aatagcagac tttttagccg agatattcaa ctaccagatg tccacggacg
    23941 aaaaaatgta tttaacgatc catactgcgc gtttagtgca tgagaatcgt tgtaaataaa
    24001 taaaaaagga ggataaatta acaagaacgc atgaaataag ggtagtgaca ttcagttggc
    24061 taaaccttcc actaataaat tggagggaat agaaatggga aaatatcaag aattagcgag
    24121 caaaattgta gaaaatgtcg gcgggaagga aaatatcaat ggtttgacac attgtatcac
    24181 aaggcttcgt ttcaaattaa aaaacgaaga aaaagcaaat gatgagatct tgaaaaatat
    24241 ggacggtgtt gtgacggtaa tgcgagcggg aggacagtac caagttgtca tcgggaatca
    24301 tgtgccagtc gtgtttgaag aggttataag agcaggaaac cttacttttg atgaggctgt
    24361 ttcaacagaa aaaatgagac cgtttgatat gcttattgat ggaatatcgg gctgtttcca
    24421 gccattcctt gctattctag ctgctggtgg gatgattcgt ggactgacag cattacttgt
    24481 cttcttaggc gcatttgacc gcggttctgg cacatttgtt atgtttgata atatcggtga
    24541 ttctgtattc caatttatgc ctgttattat cggtttaaca gctgcccgta aatttaaagt
    24601 aaatgaattc gtagggatgt tgcttggggc agcattaatg aatcctagct tgtcgctgga
    24661 agctttgagt ggtgcagcag aagcaccact gacgaccata ttttctggca ctatttttga
    24721 agcacctatt tatcaaacag tattcggcat tccctggatt gcgcgtaact acgcttcttc
    24781 tgtcattccc attatcttta ttgtgttgtt agctagccaa attcagaaac caattaaaaa
    24841 gttagtacct gagatgatcg cgaatttctt cgttccattc ttcaccgttc ttattacaat
    24901 gcccttaggt tttttactcg ttggaccagc attcacattc gcaactgata ttttaatggc
    24961 tggatttgaa acacttttag cactttcgcc agttatttat ggagcaatcg taggcttctt
    25021 ctggcaaatt ctaatgatgt ttggtctcca ttgggcaatc gtaccaatgg gattgatgca
    25081 attttctgtg aatggctggc aaaatatcat gacacctgtt gcagtagtgt cttttggaca
    25141 aactgcagca cttactgcac tctactttaa gcttagaaat ccaaaagaca aagcaattgc
    25201 aataccagcc attgtttctg gtattgtggg gattacagag ccagctattt atgggtttac
    25261 attgccacgt aaaaaaatat ttatttttac ctgtgtcggt ggtgcgttag ggggcgcgta
    25321 tagtgggtta atgaatttaa cttcttggaa tcaaggtgga ctaggcatct ttacaattcc
    25381 caactatatt agaccagatg gtaatttaac agatgtgatt aatgtattga ttgggatcgc
    25441 cattgcgatg gtggtatcct ttgcgctgac ttttttcttt tggaaggagg aagcagatga
    25501 aacagatgat agacagaaaa catcaggtaa agaaattgta aaaacaccga tacaaggaca
    25561 aatcgctcca ctgaatgcag caaaggatgc agcttttgca caaggaacat taggtcgagg
    25621 aatcttgatc taccctgaaa aaggagaagt acgtgcccct tttgacggaa cagtcatgac
    25681 cctgttcccg acgaaacatg caatcggaat ggtttctgaa gcaggtctgg aattgctgat
    25741 tcatgtcgga ttggatactg ttcagttaga aggaaaatat tttaaaagct tggtgcagca
    25801 aggagaaaga gtgaaacaag gcgatctgtt gctccgcttc gacaagaaga aaatcgaaga
    25861 ggaaggatac agtttagaaa cacctgtgat cgtcaccaat tacacggatt atttggatat
    25921 tttggaaaat caaggggaga cggtcgggcc agacgatgca cttatcaccg cactgacctg
    25981 aacggttagg tgaaagaatg gactaggctt aattattctt tttagtccac ttctttattt
    26041 tcaaaattga aaggctcttt catgatggct gagctgatag ggcgtttatc aaatttttgt
    26101 cctacagaaa ttagatggac taaattctgt tgataatttt ctgcaaaaac acaactatat
    26161 aacacgtcta gaagataaca aatcgatgta ttgatcgtaa aattaccaat tttcgaatac
    26221 agtcgttcgc gtgtcgtaag tcgcaaagcg gctgtactca ttgaagatag cgttgaatca
    26281 ccgatactgg tcaaagctaa aattggcaca tgattttgtt tcaatatttc tgcggtacga
    26341 aggatcacat tgttttcacc cgtataagaa atcagaatcc cgcacatatc actcgtgcaa
    26401 ttgtacgctt catagaacga ttcaccaaaa gtggtgacaa tcgtgacatc cattttgatg
    26461 cgcttcattt tcagcatgaa atcttgagaa atcaaagtat tcgagttact ggcgaaaatc
    26521 acgatttttt ttgcttgaag cattagttgt ttggcttttt gcagttggtc atgatgaatg
    26581 agagaaagtg tatcttgaat cgtcatctgt tctaaagaag ccattttatt tgcgatcgtc
    26641 ataataccgt ctgtggtgga aaaaggaaga ttcgcatcta cgtcttgaaa attcccttca
    26701 agataggctg tttcagctaa aaaagcatta cgaaaactga cccagccatc aaaacccatt
    26761 ttttttgcta cacggatgag tgtggacggg tggacataac atcgctcagc aatctcttgg
    26821 atggtcattt cgccaagtgc tggagaatcg cttaagagaa actgaatcac ttcattttct
    26881 gaaggagaaa aggagatttc tttgattttt tcacgtaata acatgtagat accttcttct
    26941 tgttttttta cgtaaattat aacttttttg aaaatgattt gtaaacggat ttatgttata
    27001 tagcttaata aagacatttt ttgacaagat atttacaaaa atccagaaga aaacactaac
    27061 ttttgtaaat gttactggaa agaaacgaat ttctattgtt tgttttgttt acaaaaaaga
    27121 taataaaagt gtaaaaagta aaggagtgag aacatggcaa aaggaatcaa aatcgctacg
    27181 attggtggag gcagcagtta cacccccgag ttgatggaag gatttatcaa aagatatgag
    27241 gaattaccga tacgagaaat ctggctcgta gatgtagaag aaggaaaaga aaagcttgag
    27301 atcgtcagtc agatgtctca gcgtatgtgg gatgcttctc cgtatgaagt caaaatctat
    27361 gcaactctgg atcgggaaga agcattgaaa gatgcggatt ttgttacgac tcagtttcgt
    27421 gtcggtcaat tagatgcacg aatcaaagat gagcggatcc ctagttatta tgggatgatt
    27481 gggcaagaaa caaatggtgc tggcgggata ttcaaagctt ttcgtaccgt tccagtggtt
    27541 ttggcaatcg ttgaagacat gaagcgttta tgtccaaatg cttggctgat caatttcgcg
    27601 aacccaagcg ggatggtgac agaagcagtt atcagatatg gcaaatggga taaagtgatc
    27661 ggattatgca atgtgccagt aatggcgatg atgacagaac caacaatgct tggcaagaaa
    27721 aaagaagagc tgatctacaa gtttgccggt ctaaatcact tccattggca caaagtagca
    27781 gataataaag gaaatgaccg cacggcagaa ttgattgatc gtttatacga tgaagacaat
    27841 ggattgccga aaaatatctt tgatatcccg tttttcaaag aacaattaaa acaaatgaac
    27901 atgattcctt gtggctacca ccgctattac taccgtgaag aagaaatgct ggaacatgct
    27961 ttagaagaat atcaaacgat tggtacaaga gcgcagcaag tgaaagaaac agaagcagag
    28021 ctgtttgaat tatacaaaga tccagaattg gatcataaac ctgaacaatt gcaaaaacga
    28081 ggtggtgctt attattcaga tgctgcctgt gaaacgattg cttcgatcta tggaaataaa
    28141 gaaacacaga tcgtggtatc tacaaagaat gatggagctg ttcctgatct gccggcagat
    28201 tgtgtagtag aagtcactgc ctatgttggc gcacaaggcg cacgaaatgt agcgtttggt
    28261 tcccttcctg ctgctgaaag aggctggttg caagtaatga agaatatgga attgctgacg
    28321 atcgaagcag ccgtgactgg tgattatgga acagctttgc aagcgtttac gatcaatccg
    28381 cttatacgat caggaaagac agcaaaacgg ataatggatg agttgtttat tgcacatcag
    28441 cagtatttac cgcaattcaa ggaaacaatc agccggttaa aagcagaagg aatcgaagtc
    28501 caagatgaac tggcaagaga attatcaagc aatacacatg taatggagga agtatgatgg
    28561 gattcagaaa agatttttta tggggcggag ctacagcagc caatcaatgc gagggcggtt
    28621 atgatgaagg cggacgtggg ttagcgaacg tagacgttgt gccaatcgga gaagaccgtt
    28681 ttcctgtcat tactggaaaa aagaaaatgt ttgaatttga tgaaaatcat ttttatccag
    28741 caaaaattgc gatcgatatg tatcatcatt ataaggaaga tattgcttta tttgcagaaa
    28801 tggggttcaa gacttatcgg atgtccattg cttggagtcg tatttttcca atgggcgatg
    28861 aaaaagagcc aaatgaatct gggttgaaat tttatgagga tgtctttaaa gaatgtcaaa
    28921 agtacgggat cgagccgctt gtgacgatta cacattttga ttgtccgatg catttgatca
    28981 aagaatatgg tgcgtggcgt tccagagaac tcgttggttt ttatgaaaat ctgtgccgag
    29041 tcatcttcaa tcgctataaa ggacttgtca aatattggtt gacattcaat gagatcaata
    29101 tgatccttca tgcaccattc atgggcgcag ggctgtattt tgaagaagga gaaaatgaag
    29161 aacaaatcaa atatcaagcg gcacatcatg agttggttgc aagtgccatc gcaacgaaga
    29221 ttgctcatga agtagatccg gagaacaaag taggctgtat gctggcagca ggagcatatt
    29281 atccatacac ttgcaatcct gaagatgttt gggcttctag aaaatcagat cgagaaaatt
    29341 atttcttcat tgatgtccag tcacgaggag aatatcccgc ttatgcattg aaagaaatgg
    29401 aacgaaatgg cattcagatc gaaatggaac ctggggatgc cgcattgctg aaagaacata
    29461 ctgttgattt tatctccttt tcttattatt cttctcgagt ttcgactact gacaacgaac
    29521 tcttggaaca gactgcagga aatatctttg cttctgtcaa aaatccatat ctggaagcaa
    29581 gtgaatgggg ttggcaaatt gatccattag gcttgagaat aacgatgaat gatatttatg
    29641 atcgttatca aaaaccacta tttattgtag aaaacggctt aggtgcagtc gatacgcccg
    29701 atgagaatgg ttatgtggaa gatgattatc gaatcgacta tctggcagca catatccaag
    29761 caatgaaaga tgcagtagaa ttagatggag tcgatctatt aggctatacg acttggggat
    29821 gtattgattt agtatcagct ggtacaggtg agatgaagaa aaggtacgga ttcatttatg
    29881 tcgatcgtga caacgaggga aatggcacat tagcccgttc gaagaagaaa tcattcaact
    29941 ggtataaaaa agtaattgat tcaaatggag aaaatctttc gaatgattga tcaatgattt
    30001 ataaaagtct attgtttttc agcggatttt tcgagtataa taaagctatt cgagaaacgc
    30061 aagcagaaca atagactttt tttcgcattg gctgtaaagt atgcttactt gattaagtaa
    30121 aggagaatct acatatgtat gatgtaatcg ttattggcgc aggtcctgct gggatgactg
    30181 ctgctttata tgcttcacgt tcaaacttat ccgtattgat gatcgaacaa ggcgcccctg
    30241 gcggccaaat gaacaatacg gcagaaatcg aaaactatcc tggtttcgat tcaatcatgg
    30301 gtcctgatct agcttataag atgtatgaag gtgtttcaag atttgggaca gaaaatgctt
    30361 atggaatcgt gcaagatatc aaggatcacg gcagccacaa agaagttatt tgtgaagata
    30421 aaacttacga aggaaaaaca gtcattatcg caacaggctg tatccaccgt aaattaggcg
    30481 tacctggcga ggaagaattt gctggacgtg gcgtttctta ctgtgcagtt tgtgatggtg
    30541 cgtttttccg taacaaacgt ctagtagtga tcggaggagg agactcagca gtagaagaag
    30601 ccatctattt gacacaattt gcttctgaag tagtcatcgt ccaccgtaga gatgaattac
    30661 gtgcacaaaa gatcatccaa gaccgtgcat ttgcgaatga aaaaatttcc tttatgtggg
    30721 atacagtcgt tgacgaaatc gttgggaatg aaatggtagt gacaggtgtg aaagcacgta
    30781 atgtcaaaac cggcaatgag tttgatttgg cagcagacgg agtattcatc tatgttggac
    30841 tggatccatt aactgcacca tttagagaag cagggttgac gaacgaagct ggctggattc
    30901 caacagacaa cgaaatgaag acgaatatac caggcgtttt tgccatcgga gatgttcgtg
    30961 aaaaagattt gcgacaaatc actactgctg ttggtgatgg tgggatcgct ggacaacaag
    31021 tgtataaata cttggaatct ttagaagaaa caactgcata agtttaaaaa gagtggaaga
    31081 acggtttcaa ttgttctttt actctttttt ttcgcgtgaa atctactgaa tccgatttat
    31141 gcgaatactt gcaaccgtgc ttgataaaag aatcctttct tgatttaagc gttttttggt
    31201 cctcatactt ttatatctaa taagtgaatg ctatacttat taagaaccat atttcagaaa
    31261 gaggtgttat tttcatgtct tgggaacaag tgtatgaaca atgggtacat gaagaaaatt
    31321 tagaagaaaa cttaaaaaaa caattaaatg atctgggtga agatcctgaa aaacttgaag
    31381 atgcttttta tgcaccgttg gaattcggta ctgcaggcat gcggggaatc ttagggcctg
    31441 ggatcaatcg aatgaacatc tatacggtaa gacaagcaac agaaggactt gcacgtttca
    31501 tggatacaca aggcgaagaa acaaaacgcc gaggtgtcgc tatcgcttat gactcacgcc
    31561 atcaatcacc agaatttgcc atggaagcag ccaaaacatt agcacatcac aatatcccat
    31621 cttatgtatt cgaaagtcta cgtccaacac cagagctttc ttttgcagtc cgtcatttga
    31681 agacgtttgc gggaatcatg gtaactgcat cccacaatcc agcagcttac aacggatata
    31741 aagtctacgg cgaagatggg ggacaaatgc ctcctgcaga cgcagatgca ttgacgaaat
    31801 atgtccgtga agtcagcaat ccgttaaaag ttgaagtatt atctgacgaa gaagctgaac
    31861 atagcggatt gatcacgatc atcggagaag aagtggatgc cgcttatcta gaagaaatca
    31921 aagcagtaac gattgatcat gaattggtgg aaacaatggg gaaagatttg aaacttgtgt
    31981 acacaccact tcacggaaca ggaaaaatgt tgggcgaacg tgcgttgaaa caagctggat
    32041 tcgaacaatt cgtactagtt ccagaacaag ctgtcgcaga cccagatttc actacagtca
    32101 aatcaccaaa tccagaagaa cactctgctt ttgagtatgc gatacgactt ggcgagaaag
    32161 aaggcgctga tttgctgatt gcaacagatc ctgatgcaga ccgtttaggt gcagccgttc
    32221 gtttgccaaa tggctcctat gaagtattga ccggaaacca aatcggagca ctgtttgctc
    32281 aatatatttt ggaagcacac caatcgcgag gcactttacc tgaaaacgca gcggtattga
    32341 aatcgatcgt ttctagcgaa ttacctacag caattgcgga acactatggg gctaccatgt
    32401 tcaatgtatt gacaggattc aaattcattg ctgaaaaaat tcaacaattt gaagaagatc
    32461 attcccatac ttttatgttc ggattcgaag aaagttacgg ttatttagtt aaacctttcg
    32521 ttcgcgacaa agacgcgatc caagcattgc tcttattagc agaagtagca gcttactata
    32581 aaaaacaagg caaaacgttg tatgacggct tgcaaacgat ttttgaaacc tatggctact
    32641 acgcagaaaa aacgatttct gtgacaatga gcggacaaga aggttctgcg aaaatctctg
    32701 ctttgatgga aaaattccgt gaagaagcac caacagaatt tgccggagca aaagtcatcc
    32761 aaacagaaga cttcaaagag ttgacgagaa cagaccgtga aggaaacgta gaaaaactaa
    32821 cgacaccgcc atctgatgta ttgaagtata cgctggaaga aaatggctgg atcgctatcc
    32881 gtccttcagg aactgagccg aaaatcaaat tttacatcgg tgtaaaagga aactcttcag
    32941 aagacgcagc tgaaaaagta gccgcttatg aagcgattat ccaaaagatg acagaagaat
    33001 aaaaaaactt gagactgatg gaaaaagtgg taaactttag aagtcagtct tttttcaagt
    33061 tggaggtgaa tggattgcca gacacgcaaa aaacaaaagt agagaaagtc agccaactat
    33121 tcaaaatgtt gagtgacccc actcgtctca aaattctgct gtatctgaaa gacggggaac
    33181 aaaatgtgac agcaatcacc caagcagtgg aaatggaaca atctgctgta tcgcatcaac
    33241 tgcgtttatt aagagaaaac catgtcgtca agtcccatcg tgagggaaaa gcgattttgt
    33301 atagtcttga tgattctcac gtactggata ttttgaacca gacactcaaa catgtggaac
    33361 atcaataacg ataggtgcaa atagagacaa actggactgt gtcaacgaat cttcttcgct
    33421 gacacagtcc agtttttttt aagaaaaaga caagaaaaac tgttagtctg tttcttcggt
    33481 ggtttcagtt ccataataac tatgatcttc taggtctaaa gcattcaaaa taagcgaagc
    33541 tgtttcttca atagataaag aagcgacatt gattactacg cagcccagtt tttcataaag
    33601 atcatttgca aaatcgagtt cagctcgtat tttttcgata tcagaataag cagtatcagg
    33661 atttaatccg taagagcgca tccgttcttt acggatattg tttaaaatat ctgggttatt
    33721 cgtcaatccc acgatttttt taggatcaat ctcccaaagc tgtttgggaa tatgtgcttg
    33781 tgggatcaaa ggaagattgg caacttttaa atttttgtta gctaaaaaca agctcaaagg
    33841 cgttttggaa gttcgggata cgcctagcaa aacgacatct gcttctagaa acccacgagg
    33901 atctttcccg tcatcgtatt ttacagcaaa ttccattgct ttaatccgtt tgaaatagtt
    33961 ctcattcaat aaatgaaggg cgccaggttg ccgaatgggc ttgataccag ttaagcgctc
    34021 gatttctgat atcggcggag tcatcacatc aaaactaaat aattgatgtt cttcacaaaa
    34081 agaacgcgtc atctcgatca attcttgatt gatcaatgtg tgtaagacaa gagctttttc
    34141 ttctagtgca tcttgcagtg cctgcatcaa tgttttctca tctgtcacaa atgttctgcg
    34201 gaataaattg aactcaacgc taggatattg ggccatagtg gcttgcgcta attttgtcgc
    34261 agtttctcca gcagagtcgg agatgacaaa aaaagtaacg atttctgtag aatcggaaga
    34321 catggataaa acctcacttg catttttttt atgtttatta taccatactc tagaatgtgt
    34381 acttcgtaat cattttgatt tggaggaata agtcatgaaa aaacagacat tgatcgaaca
    34441 atcactagaa acattgaaaa ataacggttt taaatatact aaaaaaagag aagcattgtt
    34501 aacttattta gtgaagcgca atcgctacgt atccgctaaa gaagtttttg actatatgaa
    34561 tcaggaattc aaaggagtaa gttacgatac gatttatcga aatctccatg attttgcaga
    34621 aatcgattta ctggaagaaa ccgatttaaa tggagagatg aagtttcgtt ttcattgctg
    34681 tcaaggggaa atcggccatc accatcactt tatctgtacg gtgtgcggaa caacgaaaga
    34741 aatccatatg tgtccaatga attatttcga agaacagctc ggtggatgta cgatcgaagg
    34801 gcatagattc gagattttcg gaagatgtga aaattgtcaa taaggattta aataaaataa
    34861 catttgataa ttttaaaaaa aagcaagatt tccttgacgg tcaaaacagc attagatata
    34921 atgtttacag gacagtcttg ttttttgaga tatatttcaa taacaattac ggttactttt
    34981 taagctcgga gggagggaat taacatgtca aaaacagtcg ttcgcaaaaa cgaatcactt
    35041 gacgatgctc ttcgtcgctt caaacgttcc gtgtcaaaag cgggtacttt acaagaatct
    35101 cgtaaacgtg aattctacga aaaaccaagt gtaagacgca agaaaaaatc tgaagcagct
    35161 agaaaacgca aaaaattcta gttctgtgat gaattggagt tggtagtgtg tcactactaa
    35221 gtagattaaa cgatgacatg aaaacagcga tgaaagcgaa agataaggaa tctttacaag
    35281 tcatccgaat gatcaagtca tctatacaaa acgagcagat taaagaaggt cacgacttga
    35341 cagaagaaga agaattaacg gtgttgtctc gcgaaatgaa acagcgacgt gattctttgc
    35401 atgagtttga agaagcagga cgtgacgatt tagctgaaaa agtaaaaagt gaaattgtga
    35461 tagtcgaaaa atacatgccg gaacaacttt ccgacgaaga aattcgacaa cttgttcaag
    35521 aagcaatcac acaaactggt gcttcatcaa tgaaagaatt tggcaaagtc atgggtgcga
    35581 tcatgcctaa agtcaaagga aaagcagatg gaaaccaagt aaatgccatt gtgaaagaac
    35641 tattacaatc ttaattttat catttaaact gcggacaatc attgtccgca gtttttttgt
    35701 gctcgtaaaa aagaaatcta aaaaatagct agacgaaaga ataggattct ttcatctagc
    35761 tggttttt
//
LOCUS       DAJSMK010000020        35384 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.020, whole genome shotgun sequence.
ACCESSION   DAJSMK010000020 DAJSMK010000000
VERSION     DAJSMK010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.020"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(97..1116)
                     /locus_tag="ON488_000990"
     CDS             complement(97..1116)
                     /locus_tag="ON488_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3231203.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(1138..2145)
                     /locus_tag="ON488_000991"
     CDS             complement(1138..2145)
                     /locus_tag="ON488_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCR3231204.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(2138..2803)
                     /gene="pgmB"
                     /locus_tag="ON488_000992"
     CDS             complement(2138..2803)
                     /gene="pgmB"
                     /locus_tag="ON488_000992"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCR3231205.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(2796..5090)
                     /locus_tag="ON488_000993"
     CDS             complement(2796..5090)
                     /locus_tag="ON488_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCR3231206.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            5350..7515
                     /locus_tag="ON488_000994"
     CDS             5350..7515
                     /locus_tag="ON488_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3231207.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            7819..8652
                     /locus_tag="ON488_000995"
     CDS             7819..8652
                     /locus_tag="ON488_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HCR3231208.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(8754..10454)
                     /locus_tag="ON488_000996"
     CDS             complement(8754..10454)
                     /locus_tag="ON488_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231209.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            10961..12121
                     /locus_tag="ON488_000997"
     CDS             10961..12121
                     /locus_tag="ON488_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCR3231210.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            12137..12580
                     /locus_tag="ON488_000998"
     CDS             12137..12580
                     /locus_tag="ON488_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3231211.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(13063..13593)
                     /locus_tag="ON488_000999"
     CDS             complement(13063..13593)
                     /locus_tag="ON488_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HCR3231212.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            13698..14249
                     /locus_tag="ON488_001000"
     CDS             13698..14249
                     /locus_tag="ON488_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCR3231213.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(14402..14875)
                     /locus_tag="ON488_001001"
     CDS             complement(14402..14875)
                     /locus_tag="ON488_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCR3231214.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            15013..16485
                     /locus_tag="ON488_001002"
     CDS             15013..16485
                     /locus_tag="ON488_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCR3231215.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            16482..17192
                     /locus_tag="ON488_001003"
     CDS             16482..17192
                     /locus_tag="ON488_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HCR3231216.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            17544..17828
                     /locus_tag="ON488_001004"
     CDS             17544..17828
                     /locus_tag="ON488_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HCR3231217.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(18109..18528)
                     /locus_tag="ON488_001005"
     CDS             complement(18109..18528)
                     /locus_tag="ON488_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HCR3231218.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(18530..19114)
                     /locus_tag="ON488_001006"
     CDS             complement(18530..19114)
                     /locus_tag="ON488_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HCR3231219.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(19161..20636)
                     /locus_tag="ON488_001007"
     CDS             complement(19161..20636)
                     /locus_tag="ON488_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HCR3231220.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            20817..21128
                     /locus_tag="ON488_001008"
     CDS             20817..21128
                     /locus_tag="ON488_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231221.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(21243..23579)
                     /locus_tag="ON488_001009"
     CDS             complement(21243..23579)
                     /locus_tag="ON488_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3231222.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            23721..24389
                     /locus_tag="ON488_001010"
     CDS             23721..24389
                     /locus_tag="ON488_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3231223.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            24392..25431
                     /locus_tag="ON488_001011"
                     /pseudo
     CDS             24392..25431
                     /locus_tag="ON488_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
     gene            complement(25668..26549)
                     /locus_tag="ON488_001012"
     CDS             complement(25668..26549)
                     /locus_tag="ON488_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR3231224.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            26708..27436
                     /locus_tag="ON488_001013"
     CDS             26708..27436
                     /locus_tag="ON488_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HCR3231225.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            27592..27909
                     /locus_tag="ON488_001014"
     CDS             27592..27909
                     /locus_tag="ON488_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCR3231226.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            27902..28510
                     /locus_tag="ON488_001015"
     CDS             27902..28510
                     /locus_tag="ON488_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HCR3231227.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            28565..29356
                     /locus_tag="ON488_001016"
     CDS             28565..29356
                     /locus_tag="ON488_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HCR3231228.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            29494..30006
                     /locus_tag="ON488_001017"
     CDS             29494..30006
                     /locus_tag="ON488_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HCR3231229.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KIKKVTLDIY"
     gene            30032..30904
                     /locus_tag="ON488_001018"
     CDS             30032..30904
                     /locus_tag="ON488_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HCR3231230.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            31080..31442
                     /locus_tag="ON488_001019"
     CDS             31080..31442
                     /locus_tag="ON488_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCR3231231.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            31451..32203
                     /locus_tag="ON488_001020"
     CDS             31451..32203
                     /locus_tag="ON488_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231232.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVKPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            32217..34019
                     /locus_tag="ON488_001021"
     CDS             32217..34019
                     /locus_tag="ON488_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231233.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAEKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            34296..35336
                     /locus_tag="ON488_001022"
     CDS             34296..35336
                     /locus_tag="ON488_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCR3231234.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
BASE COUNT        11052 a         6254 c         7287 g        10791 t
ORIGIN      
        1 tttttacaga taaacaatgt gttagaagta gtatcttctt ttacataaaa agctgaccat
       61 aggataaatg gtcagcgtat ttagtgagtc agctatttag tatgggtttt ctaaaggaac
      121 gactgtctct cttttgatca agcgatgagg gatgaccaaa cgtacgccac tgctcaattc
      181 ttcatggatc aattcgcgca gcttttgcat agcgacacgt cctaattcgg agatatcgat
      241 atcgatactt gtaaggtaag ggtgtgttaa tgttgagaag atcgagttgt tgaagctaat
      301 gacggagagt gtctctggaa tgacatagcc atacatttgc gccaactgca tcgtgcgaag
      361 ggcgaagata tcgtcaatga ccaccaatgc tgtggcttcg ttttctttca acgttttctc
      421 aaaggacaga taatcctccg gatgctctag tactacactg gataacgcag gaagaccagc
      481 catcatcatt gctttttgat aaccgaaata tcgttcgaaa tacaaacttt catgagtcgt
      541 gtttgtcaca aacaggatat tcttatgtcc attctggatc aaaaattctg ttgcttgttt
      601 acctagaagc tggttatcat tatctacata aacgatttcg ttctcatgat gataaggctg
      661 tccgatcaaa gtgaaaggga tgtggttttg gtataaataa tcaatgacag tatcttgact
      721 atctgaatac actagaataa aaccatctac ttgtttttgt aaatgcatac gctggacgtt
      781 ctctaacagc aattcaaaat ttttagcagt agcgattgct gtagtcatat cataattccg
      841 cgcttcttcg ttgattgctt ccatgatctc aagataaaat gggttaccga tccgctcttt
      901 tgaatcaaga gggggtaaga ttacgccgat ggcactggaa atgcgttttc ctagattgcg
      961 ggcagtcatg ttaggaacat aacctagttc atccataatt tttcggactt tcttctttgt
     1021 tgtctcggaa atactaggat gatcgttgat gacacgagag acggtcgagg tggcaacacc
     1081 ggcttttttc gccacatctt ttacggtaat agccatgata aaaacacctt tctcttgtta
     1141 ttgtgcagag aaccgataaa tcgtctgact gatccgttct tgaccaggat ggaggttgat
     1201 cgatccaaat ttggggaaat gaacgatatc agggatttct tgcggttcga ttgctaatcc
     1261 gtagtttgaa tgcatctgtt ttccattgac agagaaatca gcttcgaatc cagtcgtaga
     1321 aaataatacc atacttttat tagaagttgc tatagtcatt tggcgaccag aatgcttctc
     1381 gaataattgt aaggaagttt tggaaagcct aggatgatgc aaaagaaata catcatctag
     1441 tccatctgga taacatgcaa ggatctcttg cagtgttggg gattttctaa agtcgattgg
     1501 cagtttttct ttttttgtcc aatttccagt aggcagtttt tcttgatcta attcaagcac
     1561 accatctaaa aagaccgtta actgatgttc atagatgtct cttgttccat ttcctgaaag
     1621 gttgaagtag gcatggttgg tcggattgca gatggtttca acaaggctac tagcagaggt
     1681 tgtcatctct aattcgtttt ttgttaaacg gtaagtgatc gtagcagtga ttggtcctgg
     1741 ataggtagaa aattcatctt ttaagtaaaa gaccacacct attgatgatg gagttttgaa
     1801 aacttctact tcccaaaatt ggaaagacca gcctttcgtg ccaccgtgga tatggtgtga
     1861 tccgcagttt ttctccaatc tatgctcacc ccaagaagca tcccggatcc ttccggctac
     1921 aggtccgaca gttgctccaa aaaagctttt gtctgttaga acatcttcga aacgatcgta
     1981 agacaataaa acattttctg attttccttc tttgtctggt gcgaagattt ggtgcaggcg
     2041 ggcaccgtaa ttgagaagaa cgacttctaa gtagtcgttc ttcaatgtga ttttctttat
     2101 ttcagtctct ggaactggta cgacggagat ctctggatta tccatggtca tgccactttt
     2161 ctttcaagta atcgatcgta agaaaagtcg tatcagggac aagcgggatc tcctctccaa
     2221 ggtcttcagc acgtcccacg ccaattggtt gagcgccact tgagaggatg gcttggatac
     2281 cggcttgcgc gtcttcgatc ccgatacatt cttctgcttt tagtccgaca gcttttgctg
     2341 caaggaggaa gatatctggc gcaggttttc cgtttgttgc ttctgccggg tcggcaatag
     2401 catcaaagta aggtgtaaga cccatttttt caagtaggaa tggcccgttt ttacttgcag
     2461 aagcaagagc aatcttgatt ttttcttctt ttaaagaatc cagtaaaggc acgaccccgg
     2521 ggaagacatc ttttggttcg atcgtctgga tcatctctaa ataataatcg ttttttcttt
     2581 tcgctaattc tgcaaattct tcctttgaaa aagagtgttc ttttccgcca taagctaaaa
     2641 gcaaagagag tgagtcttct cggctgacgc cttttagctg ttcgttgaat gtgtggtcga
     2701 tcgtaatgcc gatttcctga ccaagctttc gccaagcacg ataatggaat tcagcagtat
     2761 cggtaatgac accgtctaaa tcaaacaata cccctttaaa catttgcttc ctcctttctt
     2821 agcgttattt ctagacgatc cgctaaagaa taagactgtt catagacgta aatttctaga
     2881 ggagaacctt ctaataactc gaaagtaact tgttcatctg tgactgagat gaacaataaa
     2941 cgtccgcgat aattgatatg gaaagaataa gctttccaag tttttggcag aaatggtgcg
     3001 aatctcaact gatcatgggc agttttcatt tgagcaaatc cttggacaat cgacaaccag
     3061 ctaccagtca tggaagtgat gtgcaagccg tcttctgtgt cgttattgta attatccaaa
     3121 tccaagcgag ctgttcgctg gtacatttct acagctttgc tttccattcc taattctgct
     3181 gctaaaatcg aatggatact tggcgaaagg gaagactcat ggacagtcat tggttcatag
     3241 aaatcaaagt ttttttgctt ttcttctttt gtaaaagtat cattgaagaa ataaatcccc
     3301 tgtagtacat ctgcctgctt gatgaagcaa gatctaagga ttttgtccca agaccaatgc
     3361 tgattcagag gaagatcgct tgtgggaata tcggatacag gcatgagatc tttatctaag
     3421 aatgtgtcat gctggacaaa gattcctaat tcttcgtcaa ctgggaagta catgttctct
     3481 gcgatatctt tccatttggc tagttcttct tcgctgatag tgatagcagc ttctttttga
     3541 taagttaaat aattttctcg cgtgtaacgc aagacccaag ctgcgatcgt atttgtatac
     3601 caattgttat tgatattgtt ctcatattcg tttgggccgg tcacaccgtg gatcatgtat
     3661 ttatttgctc gttttgaaaa atggacacgg tctgcccaga agcgtgcgat ttctgctaaa
     3721 acttccagtc cttcattttt caaatattcc gtatcgccgg tgtaattcgt ataattgtag
     3781 attgcatagg caatcgcgcc atttcggtga atctcctcga atgtgatttc ccactcgtta
     3841 tggcattcga caccagtgaa ggtgaccata ggataaagcg cgccttttaa tccttgttgc
     3901 tgagcgttgt ggattgcttg cggcagttga ttatgccgat atttcagcag attcttagtt
     3961 acttcaggtt tggctaaagc aagataaaga gggacagcat acgcttctgt atcccagtaa
     4021 gtggctccgc cgtatttttc tcctgtgaat cctttggggc cgatattcaa tcgttcatct
     4081 tcgccgtagt aagtagagaa tagttggaac aaattgaatc gaataccttg ttgtgcttct
     4141 tcgtctcctt cgatgaccac atcggcaagc ttccatcgtt ctgcccaagc cgctgtttgc
     4201 tcttcttttg cttggatata attgtttgtc tggttcgtta attctgagac agctttttct
     4261 gcttgctgcg cttctggaat atctctacta gtaagaacga taatttcttt ttccactgac
     4321 catgtctcac cttgagataa ttctgcagac aagcaaccat gtaatgctaa agtatcttcg
     4381 tgatagtcag ggatgactga ttttccatta acgaaatggc gcattgctgc agtaacagta
     4441 aattgttcaa tcccaaagtt gtttggaata gttttagtcg tcaaatagcc gatttcttct
     4501 atagttccac gatcaatctc attccaaaaa tgttcatcat agttgctgtc ttcgttttga
     4561 acatttccat ccaattttga tacgagtttg actgttccgc taccttcaag catttctata
     4621 gttaaataga tataagctga ttcttttttg acaatgctca gaaaacgttc gaaggaaatg
     4681 cgtactttat tagtagaagt agtgattgtg aatgtacgag ataatacacc atttttcata
     4741 tctaattccc agtaaaagtc ttctggttcc aaagaagcca agtcgatcag ctgatcgttg
     4801 atcgaaatat ctatcgcgat aaagttcaag gcgttgatca cttttccaaa gtattctgga
     4861 taaccatttt tccaccagcc gacacgtgtc ttatcgggat accagacacc cgccaaataa
     4921 gtaccttgat ggtggtcccc tgagtaagtt tcttcaaagt tcccgcgcat ccccatataa
     4981 ccgtttccaa tacttgttaa agattcttgc agtcgaagat tttttttatc taattgtgtc
     5041 gtgctgattt tccatggatc aatagcaaat agtcgtttga tctgtttcat ttttctcctc
     5101 ctaatgagct gttttatacg ttcataataa acgcaaccga ttgcacaagt caatagacaa
     5161 aagaaaatat ttcatagaaa aaagcttaaa aaaataaatt tttaggagaa aattatagaa
     5221 gggaacacac gtattatagg ttttatagaa tggtatagac agaaaaataa aaaataaagc
     5281 atttacaaaa aagaaaacgc acgctataat acgtttaacg aaaccgattg cgtaaaggag
     5341 ctaaacggaa tgaaaaagat atttagtttt gaattttggc aaaaatttgg aaaggcttta
     5401 atggttgtgg tagcagttat gccggcagct gggttgatga tcagtatagg gaaatcaatt
     5461 cccttgatca atcctgattg gacgccgctt gtcacaacgg gcggagtaat tgaaaatatt
     5521 ggttgggcaa ttattggtaa tcttcatatt ttatttgctt tagcaatagg aggaagttgg
     5581 gcaaaagaaa gagcaggcgg agcatttgca gctgggatct catttatttt aatcaatcgg
     5641 atcactgggg ctatctttgg tgtcacaagt gacatgcttg cgaatgaaga tgcatttacc
     5701 cacactctgt tcggtacgaa gatcatggtt aaaggatttt ttacaagtgt attggaagca
     5761 ccagctttga atatgggagt attcgtaggg atcatcgctg gatttgtcgg ggcaatggct
     5821 tataataaat actataatta tagaaaattg ccggatgctt tgtcattttt caatggaaag
     5881 cgctttgttc cgtttgttgt tatcttatgg tcaacaatcg tggcattgat tcttgctgtg
     5941 gtgtggccaa acgtacaggc tggaatcaat aattttggtt tatggattgc agaatcacaa
     6001 gaaagcgcac cgattctagc accgttttta tttggaacat tagaacgttt actattgcca
     6061 tttggattgc atcatatgct gacgattcct atcaactata cacagcttgg cggatcgtat
     6121 gagattttat caggcgcaca ggcggggaca caagtatttg ggcaagatcc gttatggttg
     6181 gcttgggcca ctgatttagt gaatcttaaa ggtgcagggg atatgtcgca atatgagttt
     6241 gtgttgcata actggacgcc ggctcgtttc aaagtaggac aaatgattgg ttcttcaggt
     6301 atcttgatgg gaatggcttt tgcgatgtat cgtaatgtcg atcctgataa gaaagcaaga
     6361 tataaatcaa tgtatttttc agcagcgttg gctgtctttc taacaggtgt aacagaacca
     6421 ttggagttca tgtttatgtt tgctgctgtg ccattatatg tcatttattc agtgatccaa
     6481 ggggctgcat ttgcgatggc agatatcttg ccattgcggg tccattcatt tgggaatatc
     6541 gaattgctga ctcggacacc gttagctatc aaagcgggtc taggtggaga tcttatcaac
     6601 ttcgtgttgt gtgtgatcgc ttttggtgtt gttacgtatt tcttagcaaa tttcttgatc
     6661 aaaaaattca actttgctac accgggacgt aacggaaatt acgacaatga cagtgaagaa
     6721 accgttgtat ctaacagcgg aacaggaaca gcagatcagc aagtggtcca gatcattcat
     6781 ttgctgggag gaaaagaaaa tatcaaagat gtcgatgctt gtatgactcg gttacgcgta
     6841 agtgtaaatg atcgagaaaa agtagggact gaagaagcct ggaaacgagc aggggcgatg
     6901 ggattgatcg tcaaagacaa tggagtccaa gcagtttatg gaccaaaagc agatgtcttg
     6961 aaatcagata tcgaagatct gctgcaatca ggagcagaga ttccagagcc agaaatggtt
     7021 tctacaggaa atggacaagc aggtagtaag caatacttag gtatagaaca agaactagtt
     7081 tccgcagctt ctggagaagt gattccttta tctgaagtaa aagatccggt attctcacaa
     7141 aaaatgatgg gtgacggctt tgctgttatt ccaacatcaa gagaagttgt tgcgccgatc
     7201 gctggaaaag tgacaagtat tttccctagc aaacatgcaa ttgggctgga aacgaaagat
     7261 ggtatcgaag ttttgatcca tatgggaatc gatacagtcc aaatgaatca gccagctttt
     7321 gagattgctg tcaaagaagg ccaagaagta ggaacaggaa cgaaattagc tgagatggat
     7381 cttgatgtga tccaaaacga agaaaaagat ccaacgatca tgatcgtatt tacaaacgat
     7441 aaagtagaag aagtagtgat caagcaatta ggtacagtga cagctggtaa agtgatcggc
     7501 tccattaaaa tgtaaggaga ggttgtgaaa aagctgtcct gcatcaagtc ataagaacag
     7561 ccaaacaaaa atagctcctc ctatttttcg tttggttggg cttattaccg agaagcagca
     7621 gtttgaatac tgtttagtgg agaggtcgtg aaaaagctgc cctgcaccaa gtgataaaaa
     7681 cagccaaaca aaaaatagct cctggtccat tgagcttatt actgaggagt tagcaggaga
     7741 acactatttg ctggagaggt tgtgacaaaa attttgtcac aacccttttg tttcgaaatg
     7801 aagacaagga gaaaaccaat gaaattcatg acactcaaca cgcatagctg gcttgagcca
     7861 gaaccagaga aaaaattgca agaattagca gataagatcc tgttagaaga ttatgaagtg
     7921 attgctttac aagaaatcaa ccaattactg gaatctgaag aagtagaacc tgcgaagcta
     7981 atgaagttct gtccggtaaa gaatcaagta cctatccgta aagataattt tgcctaccgt
     8041 ttagttcagc ttttaaagga acacggaaaa gagtattttt ggagttggga aatgagccac
     8101 atcggttatg ataaatatga agaaggaaat gcactgctta cgaaaaaaac attggaaagt
     8161 caggtcctta ccgtctccca atttcaaaag aaagaagatt atcagacacg caagatcttg
     8221 attgggaaaa caaagataga tgatcaggac atttttgtct cgagctgcca cttttcttgg
     8281 tggacagata aaaaaagtgg cttttatttt gagtggaaaa acttggaaaa ctactttttg
     8341 gaaactcgcg taccactttt tttcctaggt gatttcaata atccagtaga ctctcaaggt
     8401 tattatactg taagagaaag ttgccttctt cttcaagatt cgtatgttgt cgcgaatgaa
     8461 aaaggaaaag cagctactgt ggaaaagaaa atagatggtt gggaacaaaa tacagaaaaa
     8521 ttgcgtatag attttatttt cgtccctgaa ggaatgcagg ttaaaaaata tcaacggatt
     8581 tttgatggga tcgatagtcc aatcatcagt gatcactacg gggtggaaat cgaattagat
     8641 gtgaacgaat aaaaaatata acatataaca taaaaaaact gattaaaata aaactctcca
     8701 aacgattata ccgtttggag agttttttga tcggatgtat ttatcccttt tgcctaagca
     8761 cgtaaaagct tgtatctatg ataaataaat aaacatagca aggtaaacca gccaatcaaa
     8821 gtaagagaaa gaatgaaata gaaatagatt ggcgtttgat aatgaagcgt gagctcgttg
     8881 attccttttt gctgcttcac gattggggtc ccgatatctg ttacttcata atcagtcaat
     8941 gtttttccat tttgctgtag cacagtccga tcgtagacga taacagggat atgaacagtt
     9001 ttgtccccag tgtttttcca cttgattgtc aaaagaccgc ctggatgtgt ttttataaaa
     9061 gttgtttcgt tttctagtat ttcttcgtta taccggtcgt atttattgtc ttttgtctcc
     9121 ttatagattg gcagatagtc aggtgtggtt ttttggaaaa cgaacaagct ggtagacata
     9181 tctttgctga agaatgtttt ccttgcttct tccggcgtat cgaatagata agtatgtcga
     9241 ctgacaaatg tttcattttc ccacttttcc agatgctggt ataagttctg gatcgtctgt
     9301 gctgaaaaaa taagaatgcc aaatatactt aaaagacgga accacttttg ttcagaccac
     9361 tggttcagtg aaagggcaag gtaaagtaga agcaatagcg taaatggcac gaaaaatcga
     9421 aatggaaact ggatcaaact aataaaaggc acattttttt cgatcaatgt cgtccatgga
     9481 atcaagctag tagaaagaaa aaagaaaaca agacttgtgt acaacacgat tttttggaat
     9541 aaggtgttct tttgttgaaa gaaaataaaa agcaaaaaac ctgataatat caatatagga
     9601 aaggccttag ggtaatggag ccaataactg ccatccagat ctatcgcctt ttgactcatt
     9661 tctctgttaa caaagggagg aagaatctta ttcccactgt aaacaatagc taatcctgcc
     9721 caaatatttg ctgtcagaac aaaataaagc aagaccgact taatcagttg aagcagtgct
     9781 tttccttttt cagtctggtt aaaaaagtaa taaagataaa aagggatata catcaaagct
     9841 aacatgatcg aagacagtaa atggatctgt gtcataagtc ccactgagac agcgactttg
     9901 ataacaggga actttttatg aaggacgaaa tcagcaatag ggatcataca taaaggataa
     9961 aaacaagtcc cccagctagt gaatccttgg ttgatagacc agtattgaat agaatacgta
    10021 ctcatgaata aaacggctac tggtacactt acccaatttc gaacattgac atatctcagt
    10081 aaaatcagca tagaaaatcc tgaaataaga taaagaatga aatttgaaag aatctgataa
    10141 tgaaaccagc tacctgcaag caacacgatc aatccttgta aataagcgaa aaatgggccg
    10201 taaacggcat tcacgatcct gccactttgc tggaatccat aaagggaagg aaaataatgg
    10261 aaatccccat atttaatttg ttgcgcggca tcatagaacc gattgtaatg gaatggggca
    10321 tcagcaccca aaattagttt atgtgtgaat aaatgaggca tgagaaatgc caaagcaatg
    10381 aaaaaaattg ctaaaaatgg gccatatttt ttcaattgtc gaactccttt gcaaacttta
    10441 gataaattca tcatatatcc tatgcgagag gtaggcaaga aattagaaaa ttcatgaaaa
    10501 tatttatgaa ttttacaaga aaaacataag tgaaagttct aaggagagag gatgcgacat
    10561 aagttttgtt gcatctcctt gttttgaaac agaatttttc ttaatactcg aaacaaagta
    10621 gctttttcat gacctctcgg taaacggtgt tcaatcagct gcttctcggt aataagctca
    10681 ctagcctaga aaatatgaga agctattttc tgactagcgc tcttattact caaagcataa
    10741 cgcagttttc acaacctctt ccttaaacgg tgttcaaaag cttgcatctg cggtaataag
    10801 cccaacccaa caaaaaatat gagtagctat ttttttgggc tgtacttatt acttgatgca
    10861 ggacagcttt ttcacaacct catcggcttt cattttctat ttttttcctg aacccatata
    10921 ataaaagaaa gaacaaaaaa acttgcaagg gaggacacat gtgaagcaga gtaagcaaaa
    10981 acagtctcgt cgacttttgt ttcgtttgtt tttattaata tgtatcgtcg tagggttact
    11041 gatcgcttta tatccatttt atgtggattc tttaaatagt tttattgatc aaaaacgtat
    11101 cgaacaagta caaaaacgga ccgcagctga aattgaagtg cagcgaaaga aaatggagga
    11161 gaaaaaccaa cgattaactg accaaggatt caatcctggt actgatcctt tcaatgaaaa
    11221 gaacagaaat gaaagtacaa catccagtca attagaggaa tggctgatcg gaagtatcaa
    11281 tatacctaag atccaattaa atatttcact ttatgatcgg ctcaatggta ggatccttga
    11341 aaatggagca ggcgtcttgc aaggaacctc tttcccgctt ggtggaaatt cgacgcattc
    11401 agtgatctct gctcacagcg gtttacctaa tcgacggtta tttaccgaat tagatcgttt
    11461 agaaaacgga gacacgttta ttttgactgt tttgggggag aaattggctt atcaagttaa
    11521 aaatatacaa gtggtactgc cagatgacac gtctgttcta acgatttcag aaggagaaga
    11581 cttagttacc ttgcttacat gtacgccgta tatgatcaac acgcatcgtt tgctagtgac
    11641 aggacatcgg attccttata acgaatcggt aaaaaaagaa gaaggaaaag gaaatcagga
    11701 aagaaccatg cggcaatggt ttattcttgc aggaacgata atagctgtag tcatactgtt
    11761 agtgtttatc ggacgactaa tctatcagta tagattaagt aaaaaagtgc ttgatttttc
    11821 atttattatt agtgattcgt cagggaaacc ggtaaatggt agttcattca ttttgaaaca
    11881 taagaaaaaa acacttacta gaaatggtgt gccgttttca gtacaaagcg accatcatgg
    11941 gaaagtcaag ctggatcaat tgcctggtgg aacttatcga atcgtttcag ctgatgatcc
    12001 taaagttgct gtttcttttg gtattagaaa agtaaaacaa gagaagatat acttttttga
    12061 ggggcgaaaa cttgtaaaag agcttcaaaa aaatggtttt tattttaaaa tcaatgaata
    12121 agtaaggaga gaaaaaatga tccgcacaac aacaaaattg tctgccaaag aactggaatc
    12181 tgttctatcg atttggctgc atgctaactt ggattctcat gaattcattc catcaactta
    12241 ttgggagaat caagtagaat ctgttaggaa agctttacca gatgcagtga tttacttagc
    12301 agaaatagat caagaaatta ttggttttgc tggggtgatt gatcagttta tcgcaggaat
    12361 ctttgtgaaa agggaatacc ggcaacaaag aatcggtacg caactaatga aaaaaataaa
    12421 agaaaccaat aaaacactga ctttgacagt ctatcaaaaa aatcaatcag ctattcattt
    12481 ctatctttca caaggtttta caattcaaac acagcaaaaa gatgaagcag taaatgagga
    12541 ggaacttgtg atgaaatgga atcaaaacgc tgatttttga tgaacagaat aacgaaataa
    12601 tgctcccagc ctaatttttt gctgggagca ttatttcatt ttgaagtcac taatttaact
    12661 gtgtgaatat gcagttgtta caatctttga taaacggtgt tcaatcagct gaccctcggt
    12721 attagctcaa aaaacggcaa aatatgagga actatttttc catttgtttc tctaatactc
    12781 aggtcaaaac gctgatttca caacctcttg ataaacggtg ttcaaacggc tgcttctcgg
    12841 taataagccc actagcctag aaaatatgaa aagctatttt ctaactagcg ttcttattac
    12901 tcaaagcata acgctgattt cacaacctct tgataaacgg tgttcaatca gctgaccctc
    12961 ggtattagct caaaaaacgg caaaacatga ggaactattt ttccgtttct ttctctaata
    13021 ctcaggtcag aacgctgatt tcacaacctc tctttcacaa ccttatttta ctcgtttata
    13081 attttcatcg aagtattttc cgctacggat atcatctggc attccatcgt atggttcttc
    13141 gctaataaca tcttcattgt ctatacctgc atcacccata taagtgatcg tagcaaattc
    13201 aggaacaagt aattttggat aagtttcata tttttcacga gctgcttcca tttctgcgat
    13261 atgttcgttt tggaaagtaa cagtgatttc tggatgttct tcaacccatt tagggaaaaa
    13321 gatcattccg tgaagtttct tttcatttgg cataaagtcc aatgccacgt ctgtccctgt
    13381 tggctctgtc caagtgattt tgaatacgcc gtccgtcaat ttaacgatat cagcttcttg
    13441 gtcttttacc caacggcctt tgaccattcc gccatggata cggtaatcaa cagtatggtc
    13501 atttttggca taccattcat attcccaacc attgtcatac gtatagataa agtgagttcc
    13561 aataaaatct tccaattctt taaattcttt catgtttaag catctcctta taaattaaaa
    13621 catgtaataa actacatgtt ttcgattact catttatgat agaatggatt taaagatttg
    13681 tcaaggaggg aaaactgatg gcaagaaaaa atacacttcg atatattttg ttagggttat
    13741 taagtaagaa gaagatgaca ggatatgaat tgaatcaatc gttcaaaaat gaaataggag
    13801 aattttggca agcaaaacat agtcagattt atcctgaact tgcaaaaatg gaagagcaag
    13861 gaatcattca gcatcaagta gagatcacag gtgaaaaatt ggaaaagaaa gtttatgaat
    13921 taacagaaga agggaaggaa caattggcag agtggattca tacacccacc aatgaactac
    13981 cggttaatcg agacgaattt gttctgaaat tgtatttcgt caaagacgtg aatgatccgg
    14041 cattagtaga aattattcag cagcagcgtg accttcatga agaaaaacga cttcatctat
    14101 tagagcgaaa aaaaacgatc tttcctactg aaaaagaaaa acatgaaaat tacggacact
    14161 acctgatttt agcgcatgcg atcaatcggg aaacagaata tgcaaattgg ctaacagatg
    14221 tattagaaga aagtaaccga aaaaaataaa aaaatatccg aacagtgatg gagaattcct
    14281 ttctatatga aagaaacgca gatcaccgtt cggatattct tatgttcaaa caggcctttt
    14341 ttcaagtatt tatgtagcat ctacttatta aaaagcttgg tacttaggag attagtggcg
    14401 tttagagttc ttttaacaac tgttcgtagt cagctttttc atcgacagga aggagcttgt
    14461 aagttaattc gtctgtctcg ttgtcatgaa tgatgtacat cttagcattc tcttctttga
    14521 agttaccgat ttgtaaaatc gtatagcgtt cgtcgatcaa ttcgatatct ttgattgctt
    14581 ttgaaaaaac tttacggaca tggtgcattt tcttttggcg gatttctgcc ttttctgcag
    14641 cttttgacaa agtaaatccg tcatctaaat attttttgat cagttctact tttatgactg
    14701 taggtaaacg atattttcta ggacaattcg catcagcttc gatcgaacga atgaatccct
    14761 tttgttccca ataccttaat tgacgtggag acacacctac gatatcactt aattcactga
    14821 tgccaacaac caattgatca ttttccaaca aacgtttaag ggaagcccca accatttttg
    14881 tcactccttt tgtcctcttg cttcccttaa ttatatccgt attaacttat gtgtcaagta
    14941 ggttgacaaa tagcgaattt aggactaaag tattctagta gtttcagaaa aaattcagaa
    15001 agaaggagaa atatgagtaa caaccaaccc gtagatattt acggaaaacc atataatcgg
    15061 acacttttag ttgttgtctt attaattggt acattttgta ccgttttgaa tcagacctta
    15121 ttgacgacag cttttcctac attgatgaaa gctttcgata tttcagcgtc tgatgtgcaa
    15181 tggttaacga ctggtttctt gctagtcaac gggatcatga tcccaataac agcatggctg
    15241 atcaataaat tcagttcaag aaatttatat ctttctgcca tgacgatctt tttgatcgga
    15301 acgattactt gctttacagc acctaatttt agtacattac taatcggtcg tttgatccaa
    15361 gcttgcggtg tgggagtatc gatgccatta ttgcaaaata tcatgctatc tattttcccg
    15421 ccagaaaaaa gaggatcagc aatggggatg tcagggatcg ttattggact tgctcctgct
    15481 ttaggcccta cattatctgg ttatatcatt gataactacc attggcgtga cttgtttggt
    15541 atggtactgc caatcgttgt tcttgtcttg gttttagcat tcttcctaat gaaaagtgtt
    15601 attccattgt caaatcctag cattgatatt ttatccgcta ttttatcaac gattggattc
    15661 ggtagtttac tttacggatt ttctagtgta ggagatgacg gctggggaag cttgaaagta
    15721 attggtttct tagttgttgg tgtgattttc atcgccttgt tctcatggcg tcaattacat
    15781 ttggaacatc cattcttgga acttcgtgta ttcaaatcat ctacattcac gattgcagct
    15841 gttttagctg gtgtaacaaa tatggcgatg gtaggggcag aaatggtcgt accattgtat
    15901 attcaaaata ttcgtggaga atcagcattc cattctggct tgatgttgtt gccgggtgca
    15961 ttgatcatgg gggctatgat gcctgtgacg ggtgcgattt tcgataaata cggcgcgaaa
    16021 cgtttagcca tcacagggat gttcattttg acagcggcaa ctgcaccatt tgctttcttg
    16081 acaaaaacga ctccagtttt atatatcgtg atcctttatg cgatccgtat gtttgggatc
    16141 tccatggtca tgatgccggt aacgacttct ggtatgaatg cattgccaaa taacttgatc
    16201 agtcatggga cagcggtaaa taatacattc cgtcaaatcg caagctcgat tggtacagct
    16261 attttgatca gtgtgttgac gaatgtgaca aaagcaaata tcccaagcaa atctgtattg
    16321 gataatacgc cattagctta taaagatcag gcaatcaatg ccacactgtc aggttaccat
    16381 gccgcgttta tcgtagcgat catctttggg attcttggct ttattattgc ctttttattg
    16441 aagaaaaaag aacctgttct aatgaaagcg ggggataatg catgattatt ggagttttga
    16501 ttgtcagctt gcttgctttt gctttaacga acgtgttcgc taaaaaaaca tggcaaacct
    16561 ttttatcttt gattttcgga ctaatcttcg tcgcttcact aagtttgatc gtcgctaatt
    16621 tgtccaatca ctttggaatg gaaaaagtaa cggaaacaaa aacagaaaaa attgtttcca
    16681 gtgctgattc ccaaggagca gatatgcttt tgtataaagc tttagggaat ggaaaagaaa
    16741 aagtgtatct ttaccgaaca aatgaaaaac aagaaaaacc aaaagcaact ggtacggata
    16801 acgaaacaaa taaagtagaa aagacagacg gcgatgctga aaaagtgacg aaaactactt
    16861 attgggaata caaaaacgac atgtataaat tctggttcaa tattgctgat aacaatcacg
    16921 aatatgacag ccgagtgaat acattcaaaa tcccagagac atgggtagaa ttaagtacgg
    16981 accaagcagc caagttagct gaattagtga agaaacagca aagtacgatg gaaagtgaag
    17041 caaaagctta tgttcaagac ggtatggtaa aagcaatgac tgaaaatcca aaaatgagca
    17101 aagcagagca agaacaacgt acgaaagcct tagctgctga attccaacaa caagcattcg
    17161 caaaattagt gaaagaagca aaaggcgaat aatattttga acaccatgta ggaggttgtg
    17221 aaaaagctgc tctgcatcaa gcagtaagaa caatcagata aaaatagcac tccatatttt
    17281 tcatctgatt gggcttagtg ccgtagatgc aagcttttga acaccgttta aggaagaggt
    17341 tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca gcttctcatg
    17401 tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt ttattcgaaa
    17461 aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat gctatactag
    17521 atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca aaaatctatg
    17581 cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata agaaaagaat
    17641 tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccgtat gaaggcagta
    17701 tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt ggactacgaa
    17761 aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt acagtgaagc
    17821 aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac ggtgttcaaa
    17881 agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca tgtttacaaa
    17941 atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa acggcgttca
    18001 atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta tttttccatt
    18061 tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc ataatggttt
    18121 ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt ccaaccaatc
    18181 taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt gtgcattgga
    18241 gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg cagttttgat
    18301 gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat cgtggctagg
    18361 gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc cgatatgtgg
    18421 tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa cagcagcttg
    18481 gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat taatcaccct
    18541 gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc attgtatggt
    18601 gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt ggtggtatga
    18661 tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca tttaatggcg
    18721 tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca gcagcacgtg
    18781 caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcata cttgccggta
    18841 cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct aaatctttgt
    18901 ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg gattccagct
    18961 ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc ggatattctt
    19021 ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt acaccaatca
    19081 cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt tatgatgtca
    19141 aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac ttcttggaat
    19201 tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa gatagttttt
    19261 gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc tgatgggtcc
    19321 aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg gaaacgagtg
    19381 ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc gactaaaatg
    19441 actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg ctgaatacct
    19501 tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc accacctgca
    19561 ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa ggcaagaata
    19621 cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc aatcgttgtt
    19681 tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac ttgtacagct
    19741 ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga gttcgtgttg
    19801 atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa ttcagcacga
    19861 gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc gttacgcaaa
    19921 gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc gaaagtcgtg
    19981 ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg tttattcaag
    20041 gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat gtacataccg
    20101 atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat tgttttttct
    20161 ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc aggagtattt
    20221 gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag atgaacgact
    20281 tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt ttctacagcg
    20341 tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc tacacgttta
    20401 cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat attgttgaaa
    20461 gtcatagctg gtccttcttg agtcggacgt tttactgtac cgccagcacc gatataacgg
    20521 taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg atattgacct
    20581 ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc tgtcatgaga
    20641 gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag gaaaacaatt
    20701 caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat aatagaataa
    20761 actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga aggaaagtga
    20821 aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg aatattttga
    20881 aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca gaagagataa
    20941 ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt ctcgcacttt
    21001 ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca gtattcataa
    21061 atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa agtataccag
    21121 aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac ttcctcgttt
    21181 cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg gttgtcacaa
    21241 ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg tgcaggaaga
    21301 tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc atggacagga
    21361 tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt gatagggaac
    21421 gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa aatacacgtt
    21481 tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt tagtacaccg
    21541 atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat gatcatactt
    21601 gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc catcaatccg
    21661 ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc ttcatctgat
    21721 ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc aaaattgttc
    21781 ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag caatgtttgt
    21841 ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc tctttgagct
    21901 ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg atcgctataa
    21961 gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag gatccccgag
    22021 atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt agggataaaa
    22081 ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa tgttgtacca
    22141 acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag attcttcaat
    22201 gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt tgctgaggct
    22261 ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt gctagtgtca
    22321 agctgtgtag ggaaacttga cactcccaca cctgtcatcg ctgacatcgt actagataaa
    22381 gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac tttgccattt
    22441 acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt acttaagtta
    22501 ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt gtgctgtgct
    22561 ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc cgctttgctt
    22621 gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat agtaatcgga
    22681 aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc agaagaaagg
    22741 gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt caagaaagta
    22801 cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca aaaactcatc
    22861 tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg atgggaatct
    22921 gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg ggccagttca
    22981 ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat caattccatg
    23041 atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa aaggatatct
    23101 gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc agataactga
    23161 tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc ttctgcccgt
    23221 tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac gttttcaata
    23281 atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga gttgtttcgg
    23341 taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat taccatatca
    23401 ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt accagaacca
    23461 ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac accatccaat
    23521 gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa ttgaagcata
    23581 atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag aacaatgatc
    23641 gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct agaaattttt
    23701 caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat ccgcaattac
    23761 agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc gcattgaatg
    23821 gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt acagatatca
    23881 tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc agatttgaca
    23941 cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc gggttcaaat
    24001 taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc ctacgtgtgg
    24061 aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc ggacaaacaa
    24121 aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt ctgcctcaaa
    24181 aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc actcgccaac
    24241 agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg atcgatgtac
    24301 atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc atcacagtac
    24361 ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt cacaattatg
    24421 gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt gttttctcgg
    24481 ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg gaaaaccaac
    24541 gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag gaatatcgat
    24601 ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata tgagtctggt
    24661 agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag aagtacagca
    24721 actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga cactgaggaa
    24781 tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa tccaaggata
    24841 tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat ttttatatcg
    24901 gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa aattgaacaa
    24961 actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg aacaaatcag
    25021 agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat tggatatcga
    25081 acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt ggctgaatat
    25141 catggataac gccataaagt acaatcaaat caatggacag attcatatca aactatttga
    25201 gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga agagaccaga
    25261 gatcgaatgt ttgaaaaatt ttatcaagga gatacaagtc gtcaaatttc tgggaatggg
    25321 ctaggacttt cactggttaa aaaaattcta gaactgcatg atggacgtat tgattatagc
    25381 agtatcgaag gagtaggaac gacagcaatg atacggttaa gtaaacaata ggaaaaagaa
    25441 taaaacccct aaaaattcta ttgaaggttt ttaggggttt ttagtcgttt ttttgtgatt
    25501 agggaaatgt tcttacggtt cttttggcat aaaaatcgct gctttcttat tgaactacga
    25561 gaaatgttag aggtgtcatt gaaacaagga catgatgcaa gaaagagagc gaaagtcatg
    25621 cgtcgctctc tttttttggg tggatagatg gacagaaaat gtagggctta gttttcttct
    25681 tgatttaaat actcccaaaa tgtatctgaa gccaaagaat gctcaccgac tttacgagta
    25741 aatgcaagat aactctctgt tgttggagaa atagggagaa tcacagtatt ttcttttaat
    25801 agattcttga ctgttttttc cataacaata gcaatcccca tgtcatttgc aatcatattg
    25861 atgatcaagt cgattcttgc tcctttataa gagatttttg gttcaaatcc agcttcgcga
    25921 cacagatcta gtacaggttg atacaagttc gtagtggggc caaggagcaa aaagttctcc
    25981 tttttcagtt cgcttagatc caatttcttt ttactagcta aaggatgatt tttaggtaga
    26041 actgctacaa aatcgtctgt ttcagtaggc aaccactcaa tcgaacttgg tggggcctgg
    26101 aaacttctag caaagtggat cgtgtcacta tgttcattgg cgtcattgta agttaattcg
    26161 acactttcca cttctttcaa ctggactgta aattcaggat ggcgtttcaa aaactcggtg
    26221 attttggaaa aacctttata attgatcatt gtcggtatcg ttaagatatt taatgaaaga
    26281 ttgttgtctt tcgtataggt ttcaagcact tcttgcatag catggtattg ttctacgaca
    26341 ttttttacat atgggagcaa taagcttcca gcttcggtca attcgatttt tctatgggcg
    26401 cgttcgaata atttgacgtc taattctgtt tctaacgaaa gaatctgttt agaaatattt
    26461 ccttgggtgg tgaattgtcg atcagcagtt ttggtgaaat tcattgtttc ggctaaatca
    26521 agaaaaactt cgaatttatg gatatccatc atattcctcc tacttattcc aataaagaat
    26581 actttaacac aaaaaatgaa ttggtgtaat cttctctgtc tgttacaatc tttcttgcag
    26641 cgaaagcaat aattacagaa atttttctga tttttttcgc ttcgtagaaa aagagaggag
    26701 ttttttgatg ccaactggag ttttgatcaa tgtaggttcc gttttgtttg gcggactaat
    26761 tggcggatta gtaggaaata aattaagtga acattttaaa gcacagctga cgatggtttt
    26821 tggtgtgtgt tcgatgggga tgggaatcta ttccattgcg ccgatgaaaa atatgccggc
    26881 tgttattttt gctttagtga taggaacagc gattggtttg attgttcatt taggtaatgg
    26941 gataaataag ggggctgcgc tgatgcaagt acctatttct aaaatcttcc ctagtgaaaa
    27001 gcttggtatg acccacgatg aatttatcag cacattagtg acggtcattg ttctattttg
    27061 tgcaagtggt acggggatct atggaagttt agattctggg atgacaggag acagtacgat
    27121 tttgatttct aaatctgtcc ttgatttttt cacagcagct atttttgcgt gtaatttagg
    27181 gtatgtcgtt tctgtgatag caattcccca attcattatt ttttatattt tgttcttatt
    27241 ggcaaaattt atttatccat tgactacacc agacatgatc ttagatttta aagcttgcgg
    27301 cggattcttg atggtcgcta ccggttttag aatgatcaac gtgaaaatgt tcccagtagc
    27361 tgacatgata cctgcaatga tcgttatcat gccactgagc tggatgtgga caaattggat
    27421 tatgccactg ttataataaa aatcaaagag aagccatttt ttgctgacta aaaaggatca
    27481 aatcttttag tcagtttttt tgtatttgac aaactgattt tgaaactata ttatatgttg
    27541 tataatatag attgaaataa aatattacac ttgagaatag aaggtgacgt aatgcacatc
    27601 cagattccaa ctgttcttct tgatggtact gtgttagcag cattaagcaa ggaagatatg
    27661 tatgggtatg ccttaacaaa aatcgtacaa gaaagtctct ctgtcagtga atctacacta
    27721 tatccggttt tgagaaggtt gaaaaaagaa ggatatcttg agacctatga tgaacctttt
    27781 gaaggcagaa accgtcgata ttactcgttg acaccaatgg gaagtcgtca tttagaagaa
    27841 attattgatg aatggattgt ttttcgagat tctttagacc ggttattgga ggagagcaca
    27901 aatgaatgaa tatttgaatg aagttgtgga tcatcttcaa gaaattcctg aagacgatcg
    27961 ttttgatttg atccagtatt atgaggaata ttttttagat tctggaaaaa cattagatca
    28021 gatcattgat gaatatggta caccaaagca gtttgcctta aaattaaaaa tcagttactt
    28081 ttcagaagaa gaacaagcag aaaacgagtt agtgaaaaat ccaaaaagac aaattcgcct
    28141 gatttggtta atcattatcg gtttatttgc ttctcctgtc ctcattccac tagcactggg
    28201 gtttatattg gttattgggg gactattggt tgctttacta gcgctcattt ttagtatcta
    28261 tgttttatgt atcagtatct taggtgttgg cctattcatg atcatctcag gaatcagtgt
    28321 gtttggacaa tcgattctga gtggattatt ctttatcggt gtcggtctgt tcgccacagg
    28381 aagcgcagta tttatttcgc cactgttgct gaaaggaaca aaagggcttt tttatgtcat
    28441 gatgaacttt gttaaatgga tgggacgacg ttttattaca aaaagagatc tgcattcagc
    28501 gggcgtttga aggaggacac ataaattgag attgaaacat tttttgatta ccggtattgg
    28561 tctgatgctt actggtggcc tcctagcagg tgcaacttat acattaggcg ctcaaaagag
    28621 tctgacttgg gataatggtc ctcggttgat cgatatggtt actgagacaa aaaaaatcaa
    28681 ggatgcaaac aaaatcgtca tccatgcaga aaatcaaaca gtttcggtca tacgcggatt
    28741 ggattttgag ataaaaacga cttatgataa gacagaaaag ccagaaataa aggagaaaaa
    28801 tggcgtgttg actgtgaatg cagtcaaaaa atcaacaggt gcaatcatta gtttagaaga
    28861 cacaagtgca caaatcacta ttgttgtccc tgcagatcat gaattatctg aattgacaat
    28921 cgaagggaat aatagtgcaa ttgatatcaa cgaagtatca atcaaaaaag tgaatactaa
    28981 gacacatgat ggctgggtat cgttcaatga atttacagga ggaacaataa ctgcgaaaga
    29041 tgaattaggc tcacttcgac tagatgaggc caatgtggat aacttgatcg tcacaggtga
    29101 aaacagcaac ttccatctag aagacagttt gatcagcaaa gaaggaaaag tcatcctaaa
    29161 cggtggtaat ttatctttgc atgagatgga aaacagtggc tatactatcc aaacgtctgg
    29221 tgaatcttat attgaaaaag actaccagcc aataacaaat actttgttag aacaaggaca
    29281 gaaaaagcta aagatcactg ctaaagacac atcgatcaat attacgacgg atcaagagga
    29341 caatgaaaca gattgatcct gtactcaact ggatatttta agaaaaaaca gcaaagatcc
    29401 ttccaatctt tgctgttttt catcgcttaa cgcacataac tatagtaaaa taagaaagaa
    29461 aatatctaaa aagaaaacag ggtgaaagag tatatgaagg tagaagaagg tcaaagagaa
    29521 aagttaaaga cagaaatgga aagattacat acttatatca ctcaactaag ccaaaccttc
    29581 tatgatccag acaaagaaaa agtgatggtt aattacccga acaattcaga aggtcgccaa
    29641 ttagagcaag tgtaccatga agttttcaaa catttattga cggtgaagaa agagctggat
    29701 tattattctt taccgattat cgatacagga atattgaagt atgatgggaa gaaggaacga
    29761 tttatcttta aatctgttcg ggaagatttg cctctttcag cagggatgga tctagaggtc
    29821 ttggtagaag actattttac agaagaaaag cactgggttc gaacaaaatt ggattattta
    29881 ccgcaggcag ccggagggac acaggcaagc ggttggtaca tcactgaaga caaagagtta
    29941 gaactagaag gtgtaatggc gcgcattcga aaaaaaatta aaaaagtaac attagatatt
    30001 tattgaagga taaaggagcg caggaagtag catgagagaa aaaagagcat tttatatcaa
    30061 tggttatgca gggattgtcg gattggtcgt attagcttta gttggattgt ttttcttcta
    30121 tttaggcatg tggcaagcga aagtttgggc acttttttta agtatttttc tttggttgat
    30181 cacgttattg ttgttaagtt cggcaactgt agtcagtcct aatcaagcaa aagtaatttt
    30241 gttttttgga caatatttag gtacgattcg agaaaatggc tttttcctta cgataccttt
    30301 ggcacaaaaa atgactgttt cgttgaaagt tcggaatttc aatagttctg ttttaaaagt
    30361 caatgatttg gatggaaacc ccatcgaaat ctcagcagta gtagtcttta aagtcgttga
    30421 tacagcaaag gcattattcg atgtagcgta ttatcaagat tttgtagaaa tccaaagtga
    30481 gacagccatt cggcatatcg ctagccaata cccgtatgat acattcaatg agaatgattt
    30541 gacgcttcga ggaaacacga cggcagtgtc tgacgagttg caaaaagagc tgcaagagcg
    30601 tttagcagta gcaggtgtcg aagtaatcga aacacgcttg aaccatttag cctatgcaac
    30661 agaaatcgct agtgccatgc tccaacgtca acaagcaaaa gccattttgt ctgctcgaca
    30721 aaccattgtt gaaggagctg tcacaatcac tcaaatggcc ttagagcaaa tcgaagatgg
    30781 acaagaaatc aatttcaccg atgatcggaa agtccaattg atcaataatt tacttgtctc
    30841 aatcattaca gacaaaggaa cgcaacctgt tatcaataca ggcgacatga aagaccgtaa
    30901 gtgacatact ttttgtaaga taggaagaag gagtttagga cggattattg tcttgaactc
    30961 tttttttagt tgttttaaag aaaatgacaa aattgaaaga agaatgatag ttgattcgaa
    31021 ggcagaattg ttcgcttttt tctataatca gtatataaag taagagagaa ggggaaaaag
    31081 tgaaaaaact tctgatcggt ctacttgttt tcatcgttgt ggtacttgca ggggtgaaaa
    31141 tcgcagatta cgtagttatg ggtggagaag aatactatgt acaaattacg acagatggta
    31201 caaaaacagt ttcaaaatca gactctggac aagaaacagt caactataga tatatcctgc
    31261 ctggctatac gaaagagggt aaggaaaaag aactggactt caagggacaa ttgactcgac
    31321 cgcttcgtaa aggagcatat ttaaaaatca cctggaacaa aaataaaggt gtcacttcgt
    31381 atgaagaagt cgaaaaaaaa gacgttccga aaacagcact ggaaaaacta attaaagggt
    31441 agggaaagaa atgaacaaaa tagtcgaagt acagaatgta acaaaagtat acggaaaaaa
    31501 caatgagaaa aagacgcaag cattaagcgg catcagcttc gatgtagaaa aaggcgaatt
    31561 tattgggatc atgggcgctt ctggttctgg taaatcgaca cttttgaata ttttatccac
    31621 attagataaa ccaacagatg ggcatatccg aatcaatcaa aaagatgtga ccacattaaa
    31681 aggaaatcaa ctagcagatt ttcgtgcgaa tgagattggc tttattttcc aagacttcaa
    31741 tttattagaa agcttgacag cacaagaaaa tatcgctgtt cctctttctt tacaaggcgt
    31801 caaaccaaaa gaaatcaagc aacgtgtcca aaaaattgca gaacgtttat ccatctctca
    31861 tattttggaa agctatcctt ctgagatttc tggtggacaa aaacaacggg tcgccgccgc
    31921 acgtgcattg atcacacaac caacgattct attaggggat gagcctacag gtgcgctgga
    31981 ttccaaaagt gcccgggatc ttttagatac gatggacgaa ttgaatacaa aagatcatgt
    32041 atcgattctt cttgtgacgc atgatccgtt ttctgcaagt tattgccaac gtattttatt
    32101 catcaaggat ggcggtatcc atcaagaagt gaaacgtgga gatcaaagcc gtgattcctt
    32161 ctatcgagaa atactatcta ttcttggaaa cttggaacag tagggggaga ttgactatgc
    32221 tttggaaatt atcacttact gggatcaaga gccgtttaag agactacctg gtgttattct
    32281 caggattagt tatggcatct gctatttttt acatgtttga atcaatggca agcaacgaag
    32341 cttttttgaa aagtaatacg atcgttgcgg ctacagttat cattttccga ttcggttctg
    32401 ttttactagg gatcatcaca ttcgtttata ttttatatgc aaattccttt ttgatgacga
    32461 tgcggcaaaa agactatgca atgtttatga tgctaggagc aaaaggcaga aaaatcgcac
    32521 agatgatttt ttctgaaaca ttcttagtag ggatcgcagc tactttagtg ggttcagctg
    32581 tcggtgtagg attgacaagt atcgtccacc gattattagt ggatcagtta gatctcaata
    32641 tttcgcattt tacacctttt agtattcacg ggttgttgat cactgttttg ttttttgctg
    32701 ttttgttttt attagctgct gttgtcaatg ctttttcgat tgtcaaaaaa ccgatattag
    32761 cattgattcg tgcggatcag acaccaacaa gaatcaagca gcataaattc ttgtttttcc
    32821 ttgaagtagt actgggaatt gcttttctag gctgcggtta ctatatgatg aaacacgtgg
    32881 ggacctatca agtctttggt ataggagtag ccttagttac gatcgtatta ggaacttatt
    32941 tcattttcca ttctgtgatc attttctttt tatcattact aaagaaatca gaacagattt
    33001 cattgaaaaa attgaacaat ttcacattgt cacagttaaa ctttcgtatt cgtgaatata
    33061 cacaaatgct ctcaatggtc gctatgctgt ttgccttggc actgggcgct ttgacggtag
    33121 gattaggttt taaaaatgaa attgcagact tgacagaaaa caattctgga tatgatctag
    33181 tgatgaataa tcctcgggca gaagatcagc aaaaaatcaa agaactttca ccaacacttt
    33241 ctgcttctta tactcaaaaa gaagatgcgg gaacgattta ctataatgca agtgaatttg
    33301 cggctcaacc attgatcatg ataaaacatg aagatggaac accgccgaag atcacgaaag
    33361 aaaaagttcc tgctgaaaaa atgaatgaac tgactgtaca agaggaactt cgaagctatg
    33421 aattgccgga acagcaagaa aaagaaatca aggtagtcag tcaatcagaa tttgatcaac
    33481 tgaacttgcc acaatccact ttacagctag ttcaggtaaa agacttccaa gcaaacctga
    33541 aaccaatcga aacacttgtt gctcaaaata aaatgaacaa tccatctttg caaaaagtag
    33601 agtacagcaa ccagaaatat gaaatgtatg aagtgtataa tggtctattc tctggttttg
    33661 aatttatggg attcttccta ggtttagctt tcttgaccat gcttgctagc tgtttgatgt
    33721 tcaagatctt gtcaggaagc aagagtgaca ttgctcgtta tgaaatgctt gaaaagatag
    33781 gaacacgacg cgggttgctt aaacaatcga tccgtagaga agtaggcgtg ttattcttag
    33841 caccaggaat cttaggtgta gtccatgtct tattcggatt acaaatgttt ggtctattca
    33901 tgcaaaatcc atacaaagat atttgggttc cgtttacgat cttcttcgta ttgtatttca
    33961 tctactatgt actgacgaca tggttatata ctggaatcgt attgaaaaag agattgtgaa
    34021 aaagctgtcc tgcatcaagt aataagaaca gccaagcaaa aatagctcct cctatttttc
    34081 gtttggttgg gcttattacc gcagatgcaa gcttttgaac accgtttgtt cggaaaaaga
    34141 ggttgtgaca atatttttgt cacaaccttt ttttcacggt cttttattag aatatagtaa
    34201 attttttctc gttactcacg gaataagctg ttaagaaaac ggtttccatg tatactggaa
    34261 tcagtgcaaa tgaaagaaaa gagggtgcaa ggaacatgga aatcaatgaa caaaattttg
    34321 gcgaaaacta tcacttgatt acgatcacga atcaaaatgg gacatctttg tctgtcagtg
    34381 atcttggggc acgggttgtt cattttcaaa caataatcga taatgaaaaa cgagagttga
    34441 tcttaggttt tgatgaagca aaagaatatc tagaaaaaga cccttatatc ggtgcttcaa
    34501 tcggacgtat ggctggacgg attacgaatg gcacattcaa attagatgat gaaacgttcg
    34561 aagtaaaaac agacccggac actggtcatt gtttacatgg tggtgcacct agctttgaag
    34621 ccaagcagtg gcattataca gtcatcaatg gtgaaaacga agcatcggtc attttctatc
    34681 agactagccc agacatggaa aacggatttc ctggaacttt agatgtagaa gtacggtata
    34741 cgctgacgaa cgatgataca tggcgagtga cggtccaagg gatcagtgac cgcaaaacag
    34801 tattcaatcc tacaaatcat gtctatttca atttaaccgg tgatccagca cagtcaatcg
    34861 acgaacatat actttggttg aatagccgat tatttgctac gctcaataaa gatacaacgc
    34921 ctacaggaga agtagtttca gtaagtggca cagcatttga cttccaacgt cctaaaaaat
    34981 taggtgaggt ctttgccagt gattttcgcc aatcaatgat agtgggcggt atcgatcatc
    35041 catttttgtt gaaaaaacaa tctggtttac taaatgctgc ggaattgaca agcccagatg
    35101 aaaaagtatc gatccaagta aaaacagatg cttcaggaat cgtgattttt acagcaaatt
    35161 ttggagaaga tggaccggaa atgcgcggga ataaattagt aaatcatggc ggtatcacat
    35221 ttgagactca agaactgcca ggagcggagc gacttgaaag ttttggagat gtcactctgg
    35281 aacctaacca agtacgcgag tttgtaacgg aatacaaaat aaatataaag aaatagaata
    35341 aattaaaaag ggagtgtgac agtgtcacat ccccttttta attt
//
LOCUS       DAJSMK010000021        34930 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.021, whole genome shotgun sequence.
ACCESSION   DAJSMK010000021 DAJSMK010000000
VERSION     DAJSMK010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.021"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            233..448
                     /locus_tag="ON488_001023"
     CDS             233..448
                     /locus_tag="ON488_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231235.1"
                     /translation="MNQEIADIKLIKEVLQESTANAIASGSGISLSTAKKLKSGERNV
                     EKLNLSDAIKITEFAIKNRHVKIEIWK"
     gene            complement(534..1445)
                     /locus_tag="ON488_001024"
     CDS             complement(534..1445)
                     /locus_tag="ON488_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3231236.1"
                     /translation="MKIKIERNQKEKSPKKNKERVISVGKHRKMVLALWLLLSCSLAF
                     GIYRNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWRNNKEAIEKRMSNL
                     EQYLTENGLALSQDMVRADIPTSSEVQSIKILDVEKHSEEFIVSFLVEQQITEGKKTQ
                     SISSAYRVTIFEDENGSHIVTSLPTMIAKPEKAKYESKQIGIESDIDAKTTEEVTDFL
                     ETFFKLYPSASEKELEYYVENKAVQPINSNLKLVELVNPTFKLKGKEIQGEIFVKYLN
                     NTTKVSNIFEFTLTLQKVKNWKIIDIG"
     gene            complement(1464..2468)
                     /locus_tag="ON488_001025"
     CDS             complement(1464..2468)
                     /locus_tag="ON488_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCR3231237.1"
                     /translation="MNVKKLSIISLTILTLSFMVVLMCVGLLFGEDSEGSNSSGASSG
                     GSNVSEEVLKHRAMVEKYAKESNISEYVLILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVAKNGKKHNFALA
                     ESFSKEKSSGQKVDYPNPIAIKKNGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGASPETGFDCSGLTQWCYAKVGLKLPRVAQDQYNAMTHIDVKDA
                     KPGDLVFFHSTYDTGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            complement(2465..4588)
                     /locus_tag="ON488_001026"
     CDS             complement(2465..4588)
                     /locus_tag="ON488_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCR3231238.1"
                     /translation="MKKKLLRIVGIIAISLCTILLLLSLIGTVAEATGLVDDTVKSGN
                     LYSQYSLDNYQLDFFVDSSWGWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQVSGFYFGFLLLMILALGVYVAYI
                     GLLKREATKAVRAVINFVTIFLLSGSFIAYAPTYITKINNFSSDVSEAALSLGTELVV
                     PNSESKGKDSVDLIRDSLFSIQVRQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRIMRKPHMLMNRKLR
                     QLNRNVIRTLAFGGGAAVGHKLEKEQSKSKFKPSGSSLRKNSRLPNDHEVPSDSTKEN
                     PVSNNKKQSRMNLAGRKMGKVLDTQALVKDKTKQVRDQVRNTPTNLKYNFHKGIEKTK
                     KAPKEFKRGLVQEKANRAELREKQRQHRDEKMAEKRKVLNETGNRHKKRRENVSIKPE
                     RQPQKDRAPKKEAPKQIVRVNPNPEIKRKLSSHEIVSKRISQPSSKKNSFQQVKQRST
                     LPKRTNQKVQKRMNPRPKSRSGEKK"
     gene            complement(4593..5873)
                     /locus_tag="ON488_001027"
     CDS             complement(4593..5873)
                     /locus_tag="ON488_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR3231239.1"
                     /translation="MHVRCGAGENLEITSKGYLSLFTSDFLAGLGFGATQMLGELEGI
                     YFGYNVDTGRNVYLKPALASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFG
                     GQAVIVDPKGERGSWKETLPEIASEINILNLTSKPENQGLLDPYVIMKKKKDSESLAI
                     DILTFLTGISSRDGEKFPVLRKAIRTVTQSNQRGLLQVITELRNDGTPVAENIADHIE
                     SFTDYDFAHLLFSDGSITQSISLEKQLNIIQVADLVLPDAETTFEEYTTMELLSVSML
                     IVISTFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQ
                     NSDDLLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDESNQKRLRDLENGQCLM
                     QDLYGRVGVVQVHPVFEELFHAFDTRPPVQKRME"
     gene            complement(5913..7679)
                     /gene="ltrA"
                     /locus_tag="ON488_001028"
     CDS             complement(5913..7679)
                     /gene="ltrA"
                     /locus_tag="ON488_001028"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCR3231240.1"
                     /translation="MQETFDWLYERSSKQATKGIDLYKIIMSEENILLAYRIIKSNTG
                     SKTSGIDNQTISDFKFQNKQKFVNDIRKTIENYQPQPVRRVNIPKSNGKTRPLGIPTM
                     KDRLIQQMFKQVLEPICEAKFFKHSYGFRPNRSTEHAIARCNFIAHKCKCHHVVDVDI
                     KGFFDNVHHGKLIKQLYTIGIKDRRVLAIISKMLKVTVAGQGTSTSGVPQGGVLSTLL
                     SNVVLNDLDWWIANQWETFQTKRKYSSVDNMHHALVKSKLKKMHIVRYCDDFKIFTTN
                     HKHAVKIYHAVKGYIKQRLNLDISPDKSKITNLRRNYSEFLGFELKVIKQKKQQYVTV
                     SRVSKKSKSRIKKEIREKIKAIQKSPTRKTVNQYNQYVRGIQNYYQKATLINHDFSSI
                     YYSCLPALYNRLKPFGKYEIPRSPPITYKKFYPLTKRTFCVRKNYLFPLDSVKWKRLE
                     FFKPHINNYTQDGRLAKLRKLKPSVYSELVTLSTMETDESLEYLDNRLSRYSMQNGKC
                     SVTGIFLRTQDVHCHHIIPRKFGGTDEFDNLVIIHKWVHRLIHAKTKETIKEYLQLLQ
                     LTNKQMKKLNKYRLECNLTEFH"
     gene            complement(8423..9652)
                     /locus_tag="ON488_001029"
                     /pseudo
     CDS             complement(8423..9652)
                     /locus_tag="ON488_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP/GTP-binding protein"
     gene            complement(9639..10028)
                     /locus_tag="ON488_001030"
     CDS             complement(9639..10028)
                     /locus_tag="ON488_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3231241.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHMPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(10111..10836)
                     /locus_tag="ON488_001031"
     CDS             complement(10111..10836)
                     /locus_tag="ON488_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231242.1"
                     /translation="MLEVMIIMNFDFDLKSFIDIFVPVLTSFAVCFITLFFTNKQHKK
                     AMKQQERQHEESLDLSKQQYADEKQRNEEQDRLSYYPYLKLIPKISEHRFAGKMVKSD
                     ENDVFKLPFELINEGLGMAFSIDFVYLEETINTNDHEVNLLSLLSAQKHIDDSLDALG
                     VSAPIDTDILRVGKKTEFELYWMKYNNEVMSIPKYSVSKWEIKIRFSDFQDRIYQQRY
                     TFITSAGYQEIHRLWSDKPQLID"
     gene            complement(10885..11388)
                     /locus_tag="ON488_001032"
     CDS             complement(10885..11388)
                     /locus_tag="ON488_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCR3231243.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFSPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPIGEVALEIQHAFFNSFEEMVEH
                     VDDIICYPDCNDMSDVAYYLIEETGAFGEVPTHLQNYIDYEAYGRDLELEGNYLVTNR
                     GTFEFIG"
     gene            complement(11400..11621)
                     /locus_tag="ON488_001033"
     CDS             complement(11400..11621)
                     /locus_tag="ON488_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231244.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            complement(11618..11716)
                     /locus_tag="ON488_001034"
     CDS             complement(11618..11716)
                     /locus_tag="ON488_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCR3231245.1"
                     /translation="MKRGSSMLGITVMCLIHTSAAADRVMERKVIK"
     gene            complement(11713..12897)
                     /locus_tag="ON488_001035"
     CDS             complement(11713..12897)
                     /locus_tag="ON488_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCR3231246.1"
                     /translation="MVQQNLDYRLLKDRRNQYGVSQNKLATACGLSRPYLNQIENGGV
                     TTSTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVQKIVQEILHLKFDYMLHED
                     YAFYSYQEQYIMGDIVVMLSHEEEKGVLLELKGRGCRQFETFLLAQKRSWYDFFDDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDKSETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIEGTTFSIINRYLRFTDKVEGKRRTNWPLNERWGRFIGRNRKEIQLTSDPKPYT
                     IERTLSWLGRQVAPTWKMAKELDRLNQTTYILDMVQNAQLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(13155..13445)
                     /locus_tag="ON488_001036"
     CDS             complement(13155..13445)
                     /locus_tag="ON488_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231247.1"
                     /translation="MIYDELVGEIYWVIEKIQSDPELEEQLRRLNFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(13435..14577)
                     /gene="dcm"
                     /locus_tag="ON488_001037"
     CDS             complement(13435..14577)
                     /gene="dcm"
                     /locus_tag="ON488_001037"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HCR3231248.1"
                     /translation="MRFLDLFAGIGGFRLGMEQASHHCIGFCEIDKFARRSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AALLRPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYIPQSRERI
                     FLIGHSRDACTEQVFPIIGPSSTSDQNIRNLVNINPSNRGMGGQVYGSDGVAPTLTGD
                     EGIKIALPARDGISVAGLLPGKFEQGNRVYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAIVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVQKCDL"
     gene            complement(14653..14817)
                     /locus_tag="ON488_001038"
     CDS             complement(14653..14817)
                     /locus_tag="ON488_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231249.1"
                     /translation="MTDKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(14810..15485)
                     /locus_tag="ON488_001039"
                     /pseudo
     CDS             complement(14810..15485)
                     /locus_tag="ON488_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            complement(15580..15954)
                     /locus_tag="ON488_001040"
                     /pseudo
     CDS             complement(15580..15954)
                     /locus_tag="ON488_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346898.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(16026..17900)
                     /gene="ltrA"
                     /locus_tag="ON488_001041"
     CDS             complement(16026..17900)
                     /gene="ltrA"
                     /locus_tag="ON488_001041"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCR3231250.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            complement(18494..19510)
                     /locus_tag="ON488_001042"
     CDS             complement(18494..19510)
                     /locus_tag="ON488_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCR3231251.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFPDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            complement(19593..19928)
                     /locus_tag="ON488_001043"
     CDS             complement(19593..19928)
                     /locus_tag="ON488_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HCR3231252.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(19938..20312)
                     /locus_tag="ON488_001044"
     CDS             complement(19938..20312)
                     /locus_tag="ON488_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231253.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(20325..20639)
                     /locus_tag="ON488_001045"
     CDS             complement(20325..20639)
                     /locus_tag="ON488_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231254.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(20752..23979)
                     /gene="fss3"
                     /locus_tag="ON488_001046"
     CDS             complement(20752..23979)
                     /gene="fss3"
                     /locus_tag="ON488_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HCR3231255.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVNCTVERHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFEKILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(24396..25562)
                     /locus_tag="ON488_001047"
     CDS             complement(24396..25562)
                     /locus_tag="ON488_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3231256.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            complement(25617..26219)
                     /locus_tag="ON488_001048"
     CDS             complement(25617..26219)
                     /locus_tag="ON488_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3231257.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFLKSILEDSFEYTILFAKQKKFINKA
                     LNLNIDERKELESELFGNLTQVQVNNLKREITARLISKLQ"
     gene            26342..26542
                     /locus_tag="ON488_001049"
     CDS             26342..26542
                     /locus_tag="ON488_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231258.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            26554..26880
                     /locus_tag="ON488_001050"
     CDS             26554..26880
                     /locus_tag="ON488_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231259.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            27033..28085
                     /locus_tag="ON488_001051"
     CDS             27033..28085
                     /locus_tag="ON488_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCR3231260.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDNSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            28161..28379
                     /locus_tag="ON488_001052"
     CDS             28161..28379
                     /locus_tag="ON488_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231261.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            28366..31044
                     /locus_tag="ON488_001053"
     CDS             28366..31044
                     /locus_tag="ON488_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231262.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            31035..31232
                     /locus_tag="ON488_001054"
     CDS             31035..31232
                     /locus_tag="ON488_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231263.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            31236..31847
                     /gene="mobC"
                     /locus_tag="ON488_001055"
     CDS             31236..31847
                     /gene="mobC"
                     /locus_tag="ON488_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HCR3231264.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            31832..33223
                     /locus_tag="ON488_001056"
     CDS             31832..33223
                     /locus_tag="ON488_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCR3231265.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            33439..33753
                     /locus_tag="ON488_001057"
     CDS             33439..33753
                     /locus_tag="ON488_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231266.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            33746..34240
                     /locus_tag="ON488_001058"
     CDS             33746..34240
                     /locus_tag="ON488_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231267.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            34308..34622
                     /locus_tag="ON488_001059"
     CDS             34308..34622
                     /locus_tag="ON488_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231268.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            34721..>34930
                     /locus_tag="ON488_001060"
     CDS             34721..>34930
                     /locus_tag="ON488_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCR3231269.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT        10884 a         6595 c         5993 g        11458 t
ORIGIN      
        1 taccaataaa taaggtttaa gataaacgca aaaagtcgaa aaattaacac ttattttgtg
       61 atattaattt taatttgcaa aacaagctat atggaaaaag tttaaacttt ttctagagtc
      121 cctattacta gttaaaaaga ccactgtagt cctctgataa atcatcataa agaccacagt
      181 agtcccctta aagtttttcc aaattaacta tctgagaaag gagagaagat ttttgaatca
      241 agaaatagct gatattaaat taatcaaaga agttttacaa gaatctaccg caaacgcgat
      301 agcatctgga tcagggatta gcttaagtac agcaaaaaaa ctaaaaagtg gcgagagaaa
      361 tgtagaaaaa ctaaatcttt ctgatgcaat aaaaatcact gagtttgcta ttaagaatag
      421 gcatgtgaaa attgaaattt ggaaatgacg gatacaacta ttatagtttt gttttttcta
      481 agtatcatat ttatgaatat gcttttgcta aacatctaat tatagattaa tttttatcca
      541 atatctataa ttttccaatt ttttaccttt tggagagtaa gggtaaattc aaagatattg
      601 cttactttag ttgtattatt aagatactta acaaaaattt ctccttgaat ttcttttcct
      661 ttcagtttaa aagtaggatt aaccaattca actaatttca aattactatt aattggctga
      721 actgctttgt tttcaacata gtattcaagt tccttttccg atgctgatgg atacagttta
      781 aaaaaggtct ctaaaaaatc ggtgacttct tccgtggttt tagcatcaat gtcagattcg
      841 attcctattt gttttgattc atattttgcc ttttctggct ttgcaatcat agtaggcaaa
      901 ctcgttacta tatggctccc attttcatct tcaaagattg tcactcgata tgcagaagaa
      961 attgattgtg tcttttttcc ctctgtaatc tgttgctcga ctaaaaatga aacgataaat
     1021 tcttccgagt gtttttcaac atctagaatt tttatagatt gaacttcgga actcgtggga
     1081 atatctgctc gaaccatatc ttggcttaaa gcgagaccgt tttctgtaag gtactgttcg
     1141 agattactca ttctcttttc aattgcttcc ttgttatttc tccatgaaaa atattctttc
     1201 gcaaaatcct ctgtaaaact ttcaacgcct gaagtattca ctaccttctc ttttataact
     1261 actttttcat gagtcgtatg ctgatcaatg gctgtgaaat ttctgtagat tccaaaagca
     1321 aggctacaag acaataaaag ccaaagagca agcaccattt ttcgatgctt gcccactgaa
     1381 atgactcgtt ctttattctt ttttgggctc ttttcctttt gattccgttc aatttttatc
     1441 ttcatgtttt ttcctctttt ctcttatttg taccgtccag caccgataag atgctgctgc
     1501 caatagcttt ctgttagatt tgtccagccc actggatctc ctgcatgaaa catgcgattc
     1561 tctcctgcat aaataccgac atgggtcaca taagtaccgg tatcataagt cgaatgaaag
     1621 aaaaccaaat cacctggttt ggcatctttt acatcaatat gggtcatggc attatactga
     1681 tcttgagcca cccgaggaag tttcagacca actttggcat aacaccattg agtcaagcca
     1741 ctacaatcaa acccagtttc gggacttgct ccaccaaaca cataagccgt tccttcatac
     1801 ttaaacgcct catcaaaaat cccttggact gttttatcat caaactgtgt tgtagttagg
     1861 tattgcttca ctaataagca ataaaacata ttgccatagt tataccgcca cccaccattt
     1921 ttcttaatcg ctatgggatt agggtaatca actttttggc cgctcgattt ttcctttgaa
     1981 aaagattcgg ctaaagcaaa attatgcttc ttcccgtttt tcgcgacatg atccagatac
     2041 ccgccaccat agttatacgc ttgaataatg ctatcttgat cacaccctag ttctttggaa
     2101 cgcttaacca aagacgcaaa atagagacat ccttgtttga tggatgcctc ggtacttaat
     2161 gaattcggtg gcaacccggc tgactccgaa ctctgcatca catcttccat tgtgccacca
     2221 gattccactt gaataatcgc caaaagaatc aggacatatt ctgagatgtt tgattccttg
     2281 gcatattttt ccaccattgc tcggtgtttc aaaacttctt ctgagacatt acttccccca
     2341 gaagaagcac ctgaactatt acttccttca ctgtcttccc caaacaacaa gcccacacac
     2401 atcaagacga ccataaagga gagtgtcaag atggttaacg aaatgatact taatttcttt
     2461 acattcattt tttctcaccc gaccttgatt ttggacgagg gttcattctt ttttgtactt
     2521 tttgattggt tcgcttgggc agagtagacc tctgtttcac ttgttggaaa gaatttttct
     2581 tacttgatgg ttgacttatt ctttttgaaa caatttcatg actagatagt tttcgtttga
     2641 tttcgggatt cggatttact ctcacaatct gttttggtgc ttcttttttt ggcgctctat
     2701 ctttttgagg ttggcgctct ggttttatcg aaacattttc ccttcttttc ttatgacgat
     2761 taccggtttc gttcaatact ttgcgctttt cagccatttt ttcatctcta tgttgtcgtt
     2821 gtttttctct caactccgct cgatttgctt tttcttggac aagtccgcgc ttgaattctt
     2881 tcggtgcttt tttcgtcttt tcaattcctt tgtggaagtt gtatttcaag ttggtcggcg
     2941 tattccttac ctgatccctt acttgtttag tcttatcttt caccaaagct tgggtatcca
     3001 gaactttgcc catttttctc ccagccaaat tcattcggga ttgtttctta ttatttgaaa
     3061 ctggattctc cttagtcgag tcagatggta cctcgtgatc gttaggtaat cgtgaattct
     3121 ttcgtagaga agaaccggat ggcttaaatt tggattttga ttgttccttt tccaacttat
     3181 gtccaactgc tgcaccaccg ccaaaagcca gagttcggat cacatttcga ttgagttgcc
     3241 gcaatttacg gttcatcaac atgtgcggtt tccgcatgat gcgccttccc attgactgac
     3301 tatcattgct ttggagattg aacatactca tgatgtcacc taatttgaaa tagataccgg
     3361 caaaggtcac gatttgcagg aacgcaacca taaagaaagg ataggtagct gaaatattga
     3421 aaaacatggt ggagatacta aaagcagtcg taatgactaa ggtaactccc gctcgcatca
     3481 taatcgtatt gaataaacga ataatcgcct tctttcccaa gctctcataa gttggtaaca
     3541 tggataacag aaaactaatt ggcagaaaca tggcgaaaat gataaagaga atttgggaga
     3601 acaacataat ccccgtcagt aagaagacaa agaatgagat accaatatta aacaacacca
     3661 aaaagaccac ggtccctagt cggttcatgg tctttgtaat acttagattc gcgttgtcat
     3721 tgtcttcaat ttcagctttt accgcttctt ctcgatcctt tcccttattt tcatctggac
     3781 tcacagataa aattttattg acccggtctt caccaatttc ttctatgttg gaatcatcaa
     3841 attgcaacaa gagccaaggt tgtcggactt gaatagaaaa caaactatca cgaatcaaat
     3901 ccacactgtc ttttcctttg ctttccgaat tcggcacaac gagctctgtt ccgagactaa
     3961 gagccgcttc actaacatcc gaactaaagt tattgatttt tgtgatatag gtaggcgcat
     4021 acgcgataaa ggaaccagag agaaggaaga tcgttacaaa gttaatgaca gcccggactg
     4081 ctttggtagc ttctcgcttt aatagtccga tatacgccac atagactcct agagctaaaa
     4141 tcattaataa tagaaatcca aaatagaaac ccgagacctg taatccattt tcagtaatac
     4201 cggctagcgt ttggatattt ttcccaatac tttctgccgt atccgaaata aaatctaatt
     4261 tgtacgcttc ttgtaccaca tacccggtcg catttgataa atacaaacta acggtccaaa
     4321 tgaaatttgt aatggcgtag agaccgtaca tcacactctt tcctaaccca tcgccccagt
     4381 tccaaggcag ccagccccac gaactatcta caaagaaatc caattgatag ttatcaagtg
     4441 aatattgaga atagagattg ccagatttaa cggtatcatc aactaatcca gttgcttccg
     4501 ctactgttcc aatcagactc aaaagaagta aaatggtgca gagactaatt gcaattattc
     4561 ccacaatccg taaaagtttc tttttcatct cctcactcca ttctcttttg aacaggcggg
     4621 cgtgtatcaa aagcatggaa gagttcttca aagactggat gcacttgtac cacaccaacg
     4681 cgaccataca agtcctgcat caaacattgc ccattttcca aatctcgcag acgcttttga
     4741 ttgctttcat cttcttgatc aagaccaaag aattcgagtg tcttcttgat ttcatgaata
     4801 tctgtgcttc gaaaggcaaa tttcagccca atgttgtttt tcagacgttc atctaataaa
     4861 tcatcactat tttgagtgac aaagtaaacg ccggcattca tagcacggcc agcacgaact
     4921 agtttattcg aaagagtttt tccttgtgcg acttgaagga agctccaggc ttcatccaaa
     4981 tccacgattt tgaaaatttc tcgattgcta tgaataaaat ccaaggcaaa tgtggagata
     5041 acaatcaaca tggaaacact aagcaattcc atcgtagtgt actcttcaaa tgtagtctcc
     5101 gcatccggca aaaccaaatc tgccacctga atgatattca attgtttctc taaactaatc
     5161 gattgtgtaa ttgaaccatc tgaaaaaagt aaatgcgcaa aatcataatc ggtaaacgat
     5221 tcaatatgat cagcaatatt ttccgcaact ggtgtcccat catttcgaag ctcggtaatg
     5281 acttgtaaca acccacgttg attgctttgg gtaacggttc gaatagcttt tcgtaaaacg
     5341 ggaaatttct ctccatcccg actagaaatt ccagttagaa aagtcagaat atcaattgct
     5401 agactttcag aatccttctt tttcttcatg atcacatagg gatcaagtaa cccttgattt
     5461 tctggtttac tggttaggtt gaggatatta atttcactcg caatttctgg taaggtttct
     5521 ttccagctac cacgctctcc tttgggatca acaatcaccg cttgaccgcc aaacaggaca
     5581 gcatagtaaa ctaaaagatt attactaaag gatttcccac caccaagtga accaagaaaa
     5641 gcggcggcca gtgcattggt gacggaacct ttgacccctt gtgaagccaa tgccggttta
     5701 agataaacat tgcgtccagt atccacattg tagccaaaat aaattccctc caattctcct
     5761 aacatttggg ttgccccaaa gccaagccca gcaagaaaat cagaagtaaa tagcgatagg
     5821 taaccctttg aagttatctc taggttttcc cccgctccac accgtacgtg caactttcat
     5881 cgcatacggc gttccaactt gttcgtattt ctttagtgaa attcagttaa attacattct
     5941 aaacgatatt tgtttaactt cttcatttgc ttatttgtta gttgaagaag ttgtagatac
     6001 tctttaatcg tttcttttgt tttggcatgg atgagtctgt gtacccattt atggataata
     6061 actaggttat caaactcatc tgtaccccca aatttacgag gaataatatg atgacaatga
     6121 acatcttgcg ttcttagaaa aatccctgta acggaacatt ttccattttg catagaatat
     6181 cttgacagtc gattgtctaa gtattcaaga ctttcatctg tttccatcgt actaagggta
     6241 accaattcag aataaaccga aggttttaat ttcctcagtt tagccaatcg tccatcttgc
     6301 gtatagttgt tgatgtgagg tttgaaaaat tctaaccttt tccatttcac gctatctaat
     6361 ggaaataaat aattcttcct aacacaaaac gttctttttg tgagaggata aaacttttta
     6421 tacgtaatgg gtgggcttct agggatttca tattttccga atggttttaa acgattatat
     6481 agtgctggta agcaggaata gtagatagaa gaaaagtcat ggttaatcaa ggtggctttt
     6541 tgataataat tctgaatacc tcgtacatac tggttgtatt ggttaacagt ttttctagta
     6601 ggagatttct gaattgcttt tatcttttct ctgatttcct tcttaattct actttttgat
     6661 ttctttgaga ctctcgaaac agtaacatat tgttgtttct tttgttttat gacctttagc
     6721 tcgaatccta gaaattctga ataatttctt ctaagatttg taatttttga tttgtctggt
     6781 gaaatatcta ggttcaaccg ttgtttaata tatcccttga ccgcatgata gatttttact
     6841 gcatgtttat gatttgttgt aaagatttta aaatcatcac aataacgtac gatgtgcatt
     6901 ttctttaatt tcgactttac caaagcatgg tgcatattat ctacactgct atattttctt
     6961 tttgtttgaa atgtttccca ttgattggca atccaccaat ctaagtcatt tagaacaaca
     7021 ttcgataata atgtagataa cacgccacct tgtgggacgc cagaagtgga agtgccttgt
     7081 cctgctactg tcacttttaa cattttagag attattgcta atacgcgtcg atcttttata
     7141 ccgatggtat aaagctgttt gattaacttt ccatgatgga cgttatcaaa gaatccctta
     7201 atgtcgacat ctaccacatg atgacatttg catttatgtg caataaaatt acatcttgct
     7261 attgcatgtt ctgtagagcg attaggtcgg aacccatagg aatgtttgaa aaattttgct
     7321 tcacatatgg gttctaacac ttgtttaaac atttgttgta tcaagcggtc tttcatagtg
     7381 ggaatgccta gaggacgagt tttcccatta ctttttggaa tgttgactcg tctaactggc
     7441 tgcggctgat aattttcaat tgtttttcga atatcattta caaacttttg tttgttttga
     7501 aatttgaaat cactgattgt ttgattatct atcccagatg ttttagaacc agtatttgat
     7561 ttaataattc tatatgctag taggatattt tcctctgaca taattatttt ataaaggtca
     7621 ataccttttg ttgcttgttt gctacttctt tcatagagcc aatcaaaagt ttcttgcatt
     7681 tgatagtatt cataatatcg taattctgta ctcactgatg gattatttct cctaacttta
     7741 aaattagtcc catcctctta ccagatcttg tgagtttcat ttaactgtat tcacttttca
     7801 aagaacaagt cttggggcta tccctccacg ttgattagac gcttcacagg tactgtgccc
     7861 ctactctcgc agaaattaag gattttcgac tattagtctt atatccaacg ctccaataac
     7921 agttgttgaa taagtgtttt ctgttttcct cgttccagtt attctagcca tacatctatc
     7981 cttaggtgct tactttgagc ctgaatatta tataaggtca ttgttcctta tcccgaattt
     8041 cataaatacg actcttactt ttcggtaata ttcgttgctt ttgcaaccca attatctttc
     8101 gataaaagtc atcctttaga cccgtacatt cgcaagttcg tcagttccgt aggaacattc
     8161 tcaccataga tagtttgtgg cgtcccggca tatcctttac catataagtt attacttact
     8221 taggtattgt tctgccgact ttacctagct tcacacgaat attcactgtt atgaatattc
     8281 gcatgtagga gtatcagacc agttgcttca accaacttga cggttttcat ttcaactgtg
     8341 aaataactag ttgtaattat ctttagttct tgataattct cccatttcat gcctatgcac
     8401 ttatagggaa acgagtcgca ccatattgga tatagtcatt catgtatcgc ttgctagctg
     8461 gcaaaaactc ttcatgaagt cccatcatat cgccaaaggg acgaaccaat tttacattgg
     8521 tatcatcata aaaatctaaa acctcatcac accgacgttt taattcatcc aatgattctg
     8581 cactcactcg aacaacatag cttaatttgt acatggattc tttggattga tccaacgttg
     8641 tttctagttc atccacggag tccaacgcat ccaagacatt ggaattggtt tcattgtcgg
     8701 actggtacgc atggttgtct aagtctttca gttctttttt cttattgcga actgtcgcca
     8761 gtgccttttt attcgtcacg atttctacat tcatactcgt gtcgattggg aaagtgaatt
     8821 gttgttgctg gtaataaaag agttcagaag atggaaactc catctcaccg acaatcgtat
     8881 taatcgttag ataggccaca taagattcat gattttcatg ttccatgtgt aagtaccgag
     8941 gcttctcttc aatcaaacag cgacttgggc gaagtaggtc atagcgcttt atcaatgttt
     9001 cagattttag ctttttctta gacaactgaa attcatattc ttcaaatggt gttccttttt
     9061 ctccataaat gtgttcaatc aaataagtta gatcactagg tgttactcgt cttactttga
     9121 atctacgagc caatttactt tccatcaatt tttcaagctt agtataccgg cgaatttctt
     9181 cattggataa cgaaacaaaa tcacccatca aatgatgatt cactccatag acaaactctt
     9241 gaagtccgga taaaaaagag ttcttgagac ttttcaggtt tacttcttcg tctgtgacaa
     9301 tcagtttgaa gccaataaaa aagcgatagt caatttgact atcgccaatc atcgatacca
     9361 atgcatccgt ctgtaagtcg attctctgtt ttgcgacttc tttcaaacga ccagttatct
     9421 cttttttcga ccgttcctgc gtggcacgaa tgctgctttc tgtcgcaatt tgtaacgcat
     9481 gaatcttacc ttcacgattt tgcgcaatca attggcgaaa gttatcgtgg acttgatact
     9541 tctgttcaag tgataagaag gagtaattgt aagggactag ttcgtagtaa gcaaagcact
     9601 ctccctcttg gttaaaaaca agattatttt caatatattt aatcgggtac ataattcaca
     9661 ctcctcacta gggtgattgg ttcatcccat cgttttttct gttctttgac tttctttcct
     9721 gcaaaagtaa ccttaaatcg caagtgataa ctaataaagg atcgtaaaaa ccctaatggc
     9781 ttctttccat caaaggtctt ttgcgacata aaccaagtga ctgccacagg tatgcccaag
     9841 tattttaaaa atgccccctc tatcatagat agtggaggca tatgagcaaa cacaatgaca
     9901 aacagcaagg ataagacaaa ccaagccatt tgattaaagg ttacaggaaa aggcagctga
     9961 aagtcattga ttgcgtaaat gactttttca actgcccaga tactggtata gctttttatt
    10021 tttttcatta gtttcacttc ctaaaaaagc gcctgataaa gacgactctg catgaatatt
    10081 aattttcttt ttaaaagtgt attccaactt tcaatctatc aactgaggtt tatcagacca
    10141 taatctgtgg atttcttggt atccagctga agtaataaaa gtatatcttt gttgatatat
    10201 tctatcttga aaatcactaa accgtatttt tatttcccat ttactcactg aatatttagg
    10261 gatactcatt acttcgttat tatatttcat ccaatataat tcaaattctg tttttttccc
    10321 tactcttaga atatctgtat caataggcgc tgaaactcct aacgcatcca gactatcatc
    10381 aatatgtttt tgagccgaaa gtaatgataa tagatttact tcatggtcgt ttgtgttgat
    10441 agtttcttct aaatacacaa agtcaattga aaaagccatt cccagacctt cattaataag
    10501 ctcaaatggt aatttaaaaa catcattttc gtcagacttt accattttac cagcaaaacg
    10561 gtgttcagat attttgggta taagttttaa ataagggtaa taacttagac ggtcctgctc
    10621 ttcatttctt tgtttttcat cagcatattg ttgctttgat aaatcaagtg attcctcatg
    10681 ttgtctctct tgctgtttca tcgctttttt atgttgttta tttgtaaaaa aaagtgtgat
    10741 aaaacatact gcaaatgaag ttagtacagg gacaaatatg tctataaatg atttaaggtc
    10801 aaagtcaaaa ttcataataa tcataacctc cagcattata tatttatcaa taattatatc
    10861 cctaaaccta tatcatgaaa atgtttatcc tatgaattca aatgttcctc tatttgtcac
    10921 aagataattt ccttctagtt ccaagtcacg tccatatgct tcatagtcaa tatagttttg
    10981 caagtgtgta ggcacctctc caaaagcacc tgtttcttca atcaaataat acgccacatc
    11041 actcatatcg ttacaatcgg gataacagat aatatcatcc acatgctcca ccatttcctc
    11101 aaaagagttg aagaaagcat gttggatttc caaagcaact tcaccaatcg gtgttccttc
    11161 tagttcctct gctaaaccac acaaccgatt gatttcctca attggtgtat attcatcaat
    11221 ctcaaaaggc aactcataat catggatcgc atactcttcg tattcgtcat ttaaaccaat
    11281 ccgttctttc acttcgtcaa aatcgacagg tgggctaaac caagccccca ccaattcacc
    11341 ttcgttatat tttccaaggt tcgcaatata tacacgcatc tgctccataa tggtccccct
    11401 tacgcaccga caatccgatt aaacaagttg agtaagacat ctttcacacc agaagcgttg
    11461 aagaccagtc ctaccgcaat cagcgcaatc accaaaaaac caatcagctt ggaaaactca
    11521 cgtttgaagc ctaaaaataa accaatgacc acaattgcca ataagactaa agattgggca
    11581 ttggttaaaa accattgata taaattttgt ccgaaattca ttttatcact ttcctttcca
    11641 ttactcgatc tgcagccgca cttgtatgaa ttaagcacat cacggtaata ccaagcatac
    11701 tgcttcctct tttcatataa tcaagttttc tattgccata ctttgttgtt ccaaaatctt
    11761 tttatgccga tccgatagct gagcattctg taccatatca agaatataag tcgtctgatt
    11821 taaccgatct aactccttag ccatcttcca cgtaggtgct acctgtcgac ctagccagct
    11881 cagtgttcgc tcgatagtat aaggtttggg gtcagaagtc agttgaattt ccttgcgatt
    11941 tcgcccgata aagcgacccc atcgttcatt tagcggccag tttgttcgcc gtttcccttc
    12001 aactttatcc gtgaaccgta agtaacggtt gataatggaa aatgtggtac cctcaatact
    12061 tcgacctttt aacaagtctt gtattgcatg gtaggcacgg tcatttttca atcgaatttc
    12121 aaagcgattc ttcgtttcgc tcttgtctaa cggaattccc aatttgatat attgttcata
    12181 gtctttttcg tataaacaaa aataaacctc actcttaagg cttccgatat acaaagtatt
    12241 tcccattcca tccttttcat cagctttcaa aagttcaccc gagcggtaac tcttaaaagt
    12301 ccggaataag gagatacatt cttccttctg acattttttc gtcaactcag gaatatccaa
    12361 taagccaact cgatcattga ttgccaaatc caagcgtttc atgacgcctc cagcttttaa
    12421 gcaatcatcg aaaaagtcgt accagctacg cttttgagcg agcaaaaaag tttcaaactg
    12481 ccgacaacca cgacctttta attctaaaag aacgcctttc tcttcctcat gagaaagcat
    12541 caccacaata tcacccatga tgtattgttc ttggtacgaa taaaaggcat agtcttcatg
    12601 aagcatatag tcaaatttca aatgcaaaat ctcttgaaca attttttgaa catccgttgt
    12661 cggaaaacga atccttacat aatcaaacag taacgtcaaa ggcaaatcgg gattgaaact
    12721 ttccagttgg tcaaaaattt ttctcatagt ttttgtagat gtagttacgc caccattttc
    12781 gatttgattc aaatagggac gactcaatcc acaagcagta gccaatttat tttgagaaac
    12841 accatattga ttgcgccgat cttttagtaa acgataatct aagttctgtt gtaccaagtt
    12901 ttcacctcca aataaggtgt taacttttca aaatgagtta acacctgttc aaacagctaa
    12961 ctatcctcgt catgacaacc attcttaatc gctgcttgct tgttttttgt gtttttgtac
    13021 ccccctgtta gatacggggg gtgagacatc atggccggct aacgccgtcc atgaacaggc
    13081 acagcaccac ggaggatttc tgcttcgcga atcctccgcg gtcagcgcct aacagtcagt
    13141 tgtgttggtt taggttactc atctgtaata ccatttactt ccaactctgc tttcatttct
    13201 aacaagtatt gacgaatatc cggttctttt gcttggtccg caatccgctc aaattctgca
    13261 attacttggt ttatttcaat tcgagcatcc gtctcctcat tcattaaata tggatcgcca
    13321 gcgactttga caccattctt gcgaatatca aagtttaacc gtcgcaattg ttcttctaat
    13381 tctgggtctg actgaatctt ttcaatcacc caataaattt ctccaaccaa ctcatcataa
    13441 atcacacttt tgtacctcct ttaatcttct ggcaatatca aaaatgaccg gaactgttac
    13501 agagtttccg gcttgcttat acaactgact atctgaattg acttgagaag ctcgatcaaa
    13561 agcccaatcg ggaaagccct gaagtcgcca acactctcta ggtgttagct tccgaatttg
    13621 atactgatcc gtgacaatcg cttgttggtc tcctgtcagt aaagtatgaa cactctgttt
    13681 tcccagacga cctcggcgac ttgtggaatt aggaaaagcc aggttcacac tgtctcctgg
    13741 cttcacctct tgatattctg tttcattttt tcgaatcatg atttttgtac caccttgttt
    13801 cgtggacaag gtgggggcgg ttccagtaac ttcataaact cgattacctt gttcaaactt
    13861 tcccggtaat agtcctgcta cagagattcc atcccttgct ggcagtgcaa ttttgattcc
    13921 ttcatcacct gttaaggttg gcgctacgcc atctgaacca tagacttgtc cacccattcc
    13981 tcgattggaa ggattgatat ttaccaaatt tctgatgttt tgatcagatg ttgaagacgg
    14041 tccaatgata ggaaatactt gttcggtaca tgcgtctcga gaatgtccga taaggaagat
    14101 acgctcccgg ctttggggaa tgtaggcctt tgagttaagc acctgccact ccacgtcata
    14161 ccccaatcca tccagcgttc ggaggatcgt ctcgaacgta gccccccctt cgtgattgag
    14221 caatccccgg acgttctcaa ggaataaaaa cttaggtcgg agaagagcgg cgaaccgagc
    14281 gatttcaaag aataaagtac ctcgagtatc ggaaaatcct tgtcgctttc ccgcaattga
    14341 aaaagcttga cacggaaatc cgccgcaaag gatgtcaact ggtccgaggg attgaataaa
    14401 ctcatctgat acacttgtga tgtcatgcat ttccacctcc ttacttgtat catgaattgc
    14461 tttataacta cgtctagcaa atttatcaat ttcacaaaaa ccgatacaat gatggctcgc
    14521 ctgttccata cctaaacgaa agccaccaat accggcgaat aaatctaaaa atctcataca
    14581 ttacctcatt cattgcaaag aaaaaagcca agaacatttt gctcttggct catacattat
    14641 taatttgtcc tactattttt tatttaatcc aactaatttc cgttgttttt cattggcctg
    14701 atcggctaca tatttaatca ccgttttgaa ctcttttgca gtagcatttt ccgataaatc
    14761 cgcaatgctc ttattgtatt tctttacaat tttcgttact tgttctttat cagtcatgta
    14821 attgaacctc caaatctttc ctactatacc ctagtggtaa aaataattct agattgtccg
    14881 cagcataatg aacttcggaa atattattcg tataatcttt tattatgata tgaagcaata
    14941 catctggatg tttactcttt acttttgcaa tgttctctct tgatttgaaa aaagcgttaa
    15001 taaatacctt tttcggcaca tgacgtccct ctgcaatttc acgttcttgt gtaaatttcc
    15061 aagcgatttt agggtcttga taaacgtaga aaatcgtcac tcgaaaatgt tttttcaacg
    15121 cccgcgagat atttttttca gcacttaata ttgcaaaagt tgcatccaga ataaaagaat
    15181 agccatgatc taagacatat ctaaatgcct gctctaccaa ccaagaagat gctttttgaa
    15241 agagactaga gtttttttcc attataatca ggaaactggg tgcgaaagta atccgcatca
    15301 ataatcacat ggttatcata attctcagct aatccaatgg caacctctga ttttccagct
    15361 ccaggactcc ctgccataaa aactgcgtct cgtccaactt cgggggattt ccctttgata
    15421 atataagaaa taaacttatc cttatttgct tttgcatact ctaaataaga atcattactt
    15481 tccatattaa ttatcccctt tcttcctact atataaaagt attatacgtt acttgaagta
    15541 taaagtcagt attgaagatc actcaatcat tcatcttttc taatttacta atttactaat
    15601 tgaatctaag aaatcatacc cttttggtac aagtggcgta taaaactcac taatcacact
    15661 gccacctgta tccacataac ctcgaccttt gatgtgcttc ataaagaagt ttttttcgac
    15721 ctccccaaac atcatggaat atccgagttc actcatacga cccaaagcca cgcgaaagtt
    15781 gaattgatcg cggattccgt ctcctaaata tttcgcatcc ggcctttggc aagccaaaat
    15841 cagaaagaaa ccagattgac gacccaacat cacgatttgt ttgagcttat tcaaaatcac
    15901 cgcactttct ttcgtcgtta acatctatag cgataggtaa gaatttgata taatctccat
    15961 cttttccccc gctccacacc gtacgtgaga ctttcacctc atacggcgtt ccatctattt
    16021 attttctatt gaatgttttg cagattacac atctttcgat aaaggttgat ttttgctatt
    16081 tgctctggca ccagtttcag ttcatgcacg tagtgatcga ttatcatttt atttgttgta
    16141 tggatcagaa gatggatatc cttatgaata attctcaagt tatcgaattt gtcgtctcca
    16201 ccaagacttt ttggcaaata gtgatgacag tgaacggctt ttgctggcaa aaattgtttt
    16261 gtaatctcac acttgcctga tttcattgag taacgagata ttctactatc taaatactca
    16321 accgttctat tcggtatttt cgattccatc aattttctta attcttggaa cacaagagac
    16381 tgtaggcttt tgtgctccaa tctttgacga ccaaacggag taaacggtgt atcctccgta
    16441 ttaaatccgt aaattgtttt tgtagatacg tcgcaaagag ggtacaaata gactccagct
    16501 actttatacg ttttcatcgt tgttgagtaa aactttttgt aagttgggga agctttgttg
    16561 gggtaacatc ttgtactaca atttgataat cggttgtaag tagtgaatga aagaacgtag
    16621 ttcatcctat tcaaatctaa attaatatga gtggcatacc tgaaataatt atgaacaccg
    16681 agcacgagag cattaaacag gagagcattt tgtgctgtag gactcttttg aatatctttg
    16741 attctttgtt taatctcttc tttaatctga tccttttttt tgttagaaat acgtgaatta
    16801 caaacccatt ttttcccttt ttgtttcacg caaatagcga atcctaaaaa ttccgactta
    16861 catttacgca aattgacgat tttagacttc tcattggaaa tatctaattt aagtctgtct
    16921 tttaggtaaa gcttgacagc gtggaaccat tttaatgctg tcggataatc attagtcatg
    16981 attttaaagt catctgcgta cctgacaata tagccttgct ttagatttgt atctcttaga
    17041 gcacgaaatt tattgtaacc tttagtatag ggatactttg tttcaaaggt atgccactgc
    17101 tttgagaccc aatggtctaa gtcgtttaga acaacattag ataatagtgg agaaatgata
    17161 cctccttgga tcgttccttt gctcgggata ccttctcctt gaatgggtga tttcagagat
    17221 tttgaaagaa tagctaagac ttgtttgtca caaattccta tattccataa ttgttttatc
    17281 agtaaacggt ggtttacatt atcaaagaaa cctttgatat caatgtctac tgcatagtgc
    17341 attttactga tgtttatgag atacataatg cgacctagag catgctttgc acttctcaat
    17401 ggtctgaaac cgtagctatg ttcataaaac ttagcttcac atattggctc cagtatctgc
    17461 ttgaacatct gttggatcat tcgatcaatc atgcatggaa ttcctaatgg gcgtttctca
    17521 ccattgggtt taggtatcat tactcgcttt atggattttg gtttgtaatt ttctaaatga
    17581 ctgagaataa gatggataaa ctctgcttgg ttcatttcct tatagttatc aattgtgaag
    17641 gaatccgttc ctggtgtcga agaccccttg tttgccttga tagtacggta tgctaaaaga
    17701 atattatttt cagaaatgat taactcatat aattgataaa actttttccc gtttctactt
    17761 tgagtaaata gctgatcgaa tgtttcttgt agatcataat attcccagta acgtattttt
    17821 gtgttcaagc gtggcacctc cataacggat tttcccacgt tcttaccaga tccttgaact
    17881 tcatctgttt caacattcat tgttattaaa tagacttagg gctatccctc cacatttgtt
    17941 agacgcttca tcggtactgt gcccttactt tcacagaaac aaagcaattt cgttattact
    18001 tatatgcacc tatctagaag tagtcattta attgatagtt ttctgcttac atcgttccaa
    18061 tgtttttagc tatcatgtat aaccttaggt atctactatg agcctgtgaa attatagctt
    18121 cttcgttagc tatcccgatt ttcatatcat ggaaccttac ttgtcggtat ctcaccatac
    18181 gtccgtatgt tcctatcttt caataagatc agccttttag acccgtacat tcgcagattc
    18241 gtcagtcatt ttcagacatt cttaccatag ttatcttttt cagccgcccg ccctatagtc
    18301 agccttatgc tcaagcactt aggcagattt cagacgactt cacctagctt cataccaaaa
    18361 ccaatctact tcattgatta gagcatgtag gagtattagc ggggatgttt cagctcaact
    18421 tgaaggcttt cattccatct ctcaaaacat tagttgtcac tattgataat ctcaataggc
    18481 ttccatttca catctattcg atgcttgtag gaaaacgatt cgcacccata taagccacgt
    18541 attcatcaaa gattaaaaag ttgggtggaa gtccaagata ggcataattc tctcctgttt
    18601 tgtagttaga catttctttc attgccttgc tacgagccat catacgttca tagaaatctt
    18661 ccacacaagc agaaatttct tccttttgtg aataaacatg aggcatcacc gtacctaaat
    18721 cagctaaatc tgcatttttg ggatcgagga taaacaattc tgcatctgac ttcaatagtg
    18781 cttcgataat ggtgaggagg aaataggtct tccctccacc tgtgccacca gcgattaaca
    18841 tatggggtaa agaatcataa gcccatactt gatttttcat caatcgcaga gtcccatttt
    18901 ctgccactac ttcgtctatc ccaattcgat tggcgatcat atcatacagt aaagtatact
    18961 ccacatagga gtctttgagt tccttttcta ctaactcaca atacagtccg ctttctaact
    19021 tcttttccaa ttttaaaagc tgatcttggt atttcccaag tgaaatttga acgcgaatag
    19081 acagtaatcc atctttcatt cgataataga ttttggggaa gtaactgata gtctctctgg
    19141 ttcggctact attcaaatct ttgaaaaagc cttcactttg agtttgtttc acttcatacc
    19201 aatggttctc tagaatcatc cgagctagct tttgtcgatg ccacaagctt cgccaatgat
    19261 caggaaaaaa gtgaatataa agcaatatca tagctcctga aaaagcgaga cttccaagca
    19321 gacatactaa atcttttata gaccaaacga tttcaatagt agaaagtgat agcttagaaa
    19381 tatcaaattg tctaaactct tgaaaataaa agacgctcat ccaaccgatg aacagagcga
    19441 gtagccagcc aagaacaaag tgataaacca agtgctgatc tcctgcgcgt atgcgatgtc
    19501 ctttgtacat tttgatggtt tccacctcca atcgaaaaag cccaatagga tttcattagg
    19561 caatttcaaa aagttatgct agtcatttac tgctacgagg aggggagttg tttcgtttca
    19621 accaattgat ttaaaaagcc ttcaatagca tccggcatct ccacaccaat ttcttccaaa
    19681 atggattctg cctgccgaca taagttttca tttacttcga caactataaa gaaagactct
    19741 tcttctccta accagtctag tacatcagag tcttcttcac tgtcgctatt ttctccaagt
    19801 aaaccttgat gtataatcag aaacattttt tcatcagagg ttaatgcttt aacgagttgt
    19861 tcctcagtca gctcgccttt tccatattga tcgagacaat ctaaaatatg ttcaacatta
    19921 atttccataa tcttcaccta tttctttctt tcattttggt tcgtaggatt tccttgattc
    19981 ggctgccgct tcaagactaa atcatccgcc ttaatgaacc aattaacggt agttccttct
    20041 cgaaaaacat aattggcaac ggtatccacg attggattga ccaactctac ctctgcatca
    20101 taagcaaact cgcgtaaggg tacattagct gggatactaa cttgaatcat tcgcccttgt
    20161 gcagaggatt ttaaattata ggttcgttct tttacctcat taccaattgt tccatcctca
    20221 ttttgcttcc gtacttctcg gcgtaatgcg gaaaaacgca acttcccaaa tgttaaacct
    20281 gaatctacga caataccttc tgttaatctc atcttctttt cctcctatgc tttcactaaa
    20341 tcatcaacat acaacacgta atcagtaaac ccacgattct caatctcata gcctttggca
    20401 accaaatggg gattcacggc ttttagcggt tggtcttgat caaaatcctt ttcaccggct
    20461 tccgcagcta ctaccacctc aatatcatcg gcccgttgct tactggaata caaatgataa
    20521 ctgcgaccaa tcaccgtagt attccgtcca tatccttctg ttataatttc tccttcaccg
    20581 gcataactta actttccaaa ggtttcagcc atatctggca cgacaaattt caattccatc
    20641 ttcttttcct cttttcattg ttagttttgg atacaaaaat agcgcgacta cttttttagg
    20701 aggcggtcgc gcacgttggt tcttaggatt tacttgtatc atctcatcac cttagttccg
    20761 gcgattccag aaataatagc ccgccgtcgc aaaaatcaaa gtaaaaccaa tgaacagtaa
    20821 aacattggaa tttttctccc cggtttgagg gaaggtcttc actgtgggac tagattcttg
    20881 agagccactt ggaacagttg gtgtttccgg ttgtttcggc gtacttagta tggttggaac
    20941 ttcttttggt gttaaggttt gagatttttc tttcaaatct tcattgtgtt ttccattgat
    21001 attcccatct ttatcgtaat tgatttccgc aaaagtaaac ttggttcctt ctggatattt
    21061 tccggtatct acttttttcg caagcacagt tttggtgaat tctttatcat ttacttcata
    21121 atcaatcttg ccagatttcc aaatttcttt gtttgtacca tccggtaata aagcatacag
    21181 aattttttcg aaagcttctt ttgagccatc cagtacatca tgagtaatcg acacatcatc
    21241 aaacatatcc accacatcac catgagtaaa ggtctgagaa ccgttttcta ggtgggcctt
    21301 tgtttggata gaaacatgac gttccaccgt acaattaaca gtttgggctt gattattcaa
    21361 gctaacatcc ttcgctactg gcttatcgcc tgcttcaaaa gcttccttat tttcatacac
    21421 atagttgaat aagacaatag ttttatttaa aacttgttcg gcggttaatt tatgctgaat
    21481 tttccaagtt cctgttttct ctttgttcgc caacgttgcg cttgtttctg caatcaccac
    21541 tggtttggct ttttcatctt tttcttgggc agcttttgtc gcatccacat caatggcttg
    21601 cgctaccaca taccagtctt ctttgatttc atgtagattg taactcaatt tatcaactag
    21661 ctcggtagaa tccagagaag ttaattcttt gtttccgtct ttccaagtcg caagagaagt
    21721 taaactatct tcttcctcag gcaaatcata gagcattaaa cggttcaaac taacagaaaa
    21781 tgctttgttc gtcagcttct cgtaaggaac ggtcaccgtt ttaattggtt gtttttggtc
    21841 ttgttcggta atggtaaaga catactcact cttcacaaag tcttctttgt tttccttaaa
    21901 agtagaacgg atttctaatg gcgtaatctt ttgaaaacct tctggggctt ctacttcttc
    21961 aagtaaataa tccccataag gaagattttc aaacttgcca taaccatcaa accctaattg
    22021 ctcgttataa gctgtggtcg cttcatcttc ggcacctgtg atttcattgg tcccttccaa
    22081 tggcgacact ttaaaggtca gatcattgaa gccagtttcg gtagtgcccg cagctgatcc
    22141 agcaaattta aagaaatcaa agccaaagcg aatcacttgt tcttttgccg taacatttcg
    22201 ggtaatcacg gcattttttt cgctatcatc cacctttttg atggatacag gatactttgt
    22261 ttcatcaagg ctatatcctt cgggcgcttt tgtttcttgc caataatact cgttgatagc
    22321 taaatgttta acggcaactt ggttcttttc gtctaaagtc aaagtgaccg tttcatcaga
    22381 acctttcgtt cccttcgcta actctggttt aaaagcctca ctccatttaa cagcttttcc
    22441 atccttagca gtaaacaagg tgtattcagc accctcaaag actgccttac cttgtgcttt
    22501 atccccagta tctttgtctt ctttcgtcaa agtggtttcg ccagtgactt cttgattttg
    22561 cccttttacg ttactggtaa caagggctac ggtttgattg gcatacttca attcgacttt
    22621 tacaggtttg aacgtattca cgaacccatg actagcttta gtttcggtca cataataggt
    22681 tcccaattcc aacgcattag caatctcttt tggtgtttcc gcatgaccgt tttcatccgt
    22741 ggtcatttct tgaacgattt caccggttgg actgtctttg cgaatggcaa acgtattacc
    22801 agctaaggaa taattgtcat tccaaagatc actccctgtt tcaactccgc ttttatccag
    22861 aatgatttgc cctttttccc gtgcgttttt tgaagtcacg taaatggttt cgcctgcttt
    22921 aatggtggta gtcatggggg tggtatcaat cgtataaggc gccggtactg atttttcggt
    22981 aatggttact tttgtaccat gaggaatctc atccaatgta gcaatgcctt ctttgtcagt
    23041 agtcacgtct tttgcaggta aagtttttcc aaagtctaaa tggaaaaccg ttcctggtac
    23101 aacatcaccc gattctttat cgactttttt gatctttaaa gaaccctccg tttccacatc
    23161 aattttgatt gtgtaggtat taggtttatc aatcgccccg gccattaaag tctgttggcc
    23221 agccttttta taggcgacag gtgttccggt accagcagat ttcttaagcg tcagcacacc
    23281 actttctttt gaattggcat ttggggtgat tatcaactga ttaccattca cacgataatc
    23341 aatgtttgcg gcattttcca caacctcatc gaactctgac aaattcagat tattcgtatc
    23401 cgtcacagta gtcgattgcc ctaatactgt tttagccgta ctattatgga aggttggttt
    23461 cttctgataa tcgtcaatgg cttgatttat ttttgcctca atggctgcga tatttacggc
    23521 actaccatct gatcgtttta ttgagtgaag ggtataccca ttaacttctt gccagatcat
    23581 cttctgtgcc acaatatgag tatctgcatc tgtacctact tttttccata aaacggaaac
    23641 taatttggct ttatcggaca tatctggtaa cgggtttttc tcatagccag gagtgaactc
    23701 attgtaaatc gggactcctg gttcaataca gaaaatatct tgtttaaagc cgttgtacac
    23761 tgcataatgc ggaacagtga cttctgacat tggacgacca tcactaaaag ttccttcaac
    23821 agcatattga tgtgctaaat ctagttctac ggttaccgtt tgtggatggg taatttcatc
    23881 agcaaaagta atcgtaggag caattgctcc aacaattgct tgaacagcca aactcaaaat
    23941 agttaataca cataatttct ttttttgttt tttatacatg aaatgttctc ctttcaaatt
    24001 aagcacaaaa aaataagatg ctcgcttgaa catctttgtt tataaagtct ttttaaaatt
    24061 tttattgact gaatagaatg gatttgagaa tgaatgagcc taaaaattta atctaaaata
    24121 cgaaatatac tgcctttaaa ttagaacaca ttttagaaca caaacatttc aaatttaatc
    24181 aaatataata aaatatattt acgggaaaac ctttataaat caaggttttt caaacttatt
    24241 caatgatacg aagaaaaaac caggtcttaa gaaagcacgt aaagcttcac agttttcaaa
    24301 acgttaatcg ttgttatacc aacgatttca gacactttct cattgcgaga aggtgtcttt
    24361 ttttcgttct ggtaatgaga aaggtaatga caatattata aaccagtgta agcaatgaat
    24421 ttttctaacg catttcgttg agctttttca gtaacatgag aataagtgtt aagggtagtt
    24481 tcagcatttt tatgacccaa tcgatcttgt gtttctttga tacttgctcc accttctagt
    24541 agaagagtag cgtgagtgtg ccggaatcca tgaatagtaa cgtgcttaaa tttatatttc
    24601 ttctctaaac gtttcaatat attatttgaa tagtccgcat gcaaaggttg attaatgtca
    24661 ccgtctgcat ttacataggt aaagataagt tgattttttg tatttgtatt tatgccaaac
    24721 tgcaaaagct ctcgagcttg ttcttttttc cagattttta acatttcaat agtttgtgca
    24781 tcaattggta atattcgttc ggaagatata ttttttgtat ttttttgaat cctgacagtt
    24841 tttcttcttg cattcttctc ttcatttcga atagttgcat agctctttct aacatacatt
    24901 agctgttctt caaaataaat gtcagaccaa tgaagagcag ctagctctcc tttacgtata
    24961 ccagtagtaa tcaaaagctg gaagattaaa atatgtttta aaggctcttc tttattgaga
    25021 atatcccaaa aagcttttag ttcttctaat gaaaagtaat tttcattttc tttcttttcc
    25081 cgctttggta gatttgtatt tgccatagga tttcggtgta atagctctgc aaaaatggca
    25141 tactcaaata tttgagagct gtaagactta agctgtttga tattcttgaa ttttaaagcc
    25201 cattcattga ctgcattctg acagtgaaca ggagtaatct tagaaatgga cttattcccg
    25261 aattttggta gtatatgcaa gcggaaaagg tcttttgtac gttgatatgt cgtttcttgt
    25321 acacgattcc tataagaagg caaccattct tcatacactg ttataaacaa gtcattagaa
    25381 ggcttatgat agccggtatc ttcaatctcg accttttttc ttgcttcgtg taacttggct
    25441 tctttttcag ttttaaaccc tttttttaca tagtattctt gctttccatt ttcatcttta
    25501 cgaacataca agcggacact atatcgtgca ccgctttttg ttgtgtactt ttgtattgac
    25561 ataactaatc tctccaatct gataacttgg cgagttggct gattgaataa ttagttttat
    25621 tgaagttttg atattaatcg agctgttatc tctcttttta gattgttaac ctgtacttgg
    25681 gttaagttgc caaataactc agattctaac tcttttcttt catcgatatt taagtttaaa
    25741 gctttattaa taaacttctt ttgtttggca aatagaatcg tgtattcaaa ggagtcctct
    25801 agaatacttt ttaaaaaaag aaagtcggag tcatcttctt gaagtttgac ttcaagtaaa
    25861 gaagtcatgg aaaagtatag attagataat tcagtaaaat aatctgagtc aagactggca
    25921 atattcttga ctattttgtc ctttttttct aaacgagcag tttttattct atcaagatta
    25981 ggttgttcta tggaatttgt ttcgtctaat cccatcaaat aacttacagg aacatggaaa
    26041 taatcagcaa ggatattcca tgtttcagta tttctaggat ttcgctcacc acggtaatag
    26101 ttcgtaagag ttgtatagtt aataccagtt tctgtactaa tttgtttaat ggtcttttta
    26161 ctggaatcaa tataaaattt tattctattc aaagtaacgc cccctatagt aaattccaaa
    26221 ctattatagc atgaaaacca caaattgagt aatattttaa ttgatattac tcgttttgtg
    26281 gtttaaaatg tgcttattaa gataaaaacc acaaagtgaa taatttgaaa ggaggcgctg
    26341 aatgataact cttaatgatc aattcattag aagcttaaga agacatagag ccgatcttat
    26401 acttactaaa aacgatgcag caaaattgat aggtataaat cggaaaacat atgtcaaaat
    26461 cgaaaatggg agcaaagaaa gtattagagc atctacttat caaaagttgg taaattggtt
    26521 acttaatgat ttgaaaatct aaataaatac aacttggcga gttggctgat tgaagaaata
    26581 gaaaatgaga ggagaaaaat aatggatgca ggaattacag taatgttaga taaacaacaa
    26641 acgaatcaat tgaaaaatta tgtttttgaa atgacaaaag aggctattga tcaagcaaga
    26701 attgataccg gattagaaag accatttcta aaaggaaaag agatggctaa atatttgaat
    26761 gtatcatata caactttttt gaaatttaaa agaatgggat tgccagttat tttattagaa
    26821 aaaatggagt tgttttcaaa agaagaatgc aaaaaatgga tattgagtca tcaaatttaa
    26881 aaaacacctc gttttttaaa tttgatgaag tagaaaaaat taaaaagagt gttcccgtca
    26941 gtttgcagat cgggggaaca ctcaataata aagttctgag aaaactttat ttgaatctat
    27001 tatagcaaat aaaatcagaa gcaggtgtga caatgaatga aaaagaagtt gaaagcttag
    27061 ttgaaaagca aggctattct aattctgata tatatgcaga attatactat caatatccta
    27121 tttttttaaa cgtaaatgaa aaatataaga aaatgaaact aagttctaag ttagtttata
    27181 tgttactaaa agatagaaat agactttcat tgaaaaataa cttgtatgat gagaatcaaa
    27241 aaattttttt gatatttgaa atcaaaaatc tcgtagaaat ttcgggaatg tcaaaaaata
    27301 caatcttatc agcactagat gaacttcaaa aagttaaact tcttgtgaaa agaaaaaatg
    27361 gcttcaataa aagtaaaatg caaatgttcc caaattttta ttatttgtta aagcctgttc
    27421 tgtgcaaaga tgatgtttat aaaattaata agataaccca tcaagaaaat agacaaaaaa
    27481 acttgatagt tcaaaatttg aactatggaa caaatcaata ttctgttgat aattcaaaat
    27541 ttgaactatg cgacacatca atgaaaacaa gagacaaaaa caattttgct gatagttcaa
    27601 aaaatgaact agaattatat aagtcttata aagatagtaa agatattaaa gaatcacata
    27661 atgatgatct tcttgaatca ctttcaacta aaaataataa attagatgaa gaattgatcg
    27721 aaacatttat tgaagaaaat cttcttaaac aaatatgggg agaaagtatt gtgaattgct
    27781 taaaactggc tagcaatagt gattatcgtc aattcgacaa ctggtacaaa aaattcaaat
    27841 atgcgattag atctgctgaa aaagaacaaa aaattcaact gaaaattatc tatgaaattt
    27901 gtaataacaa gtattttgta gatcatgtta gagaacagct atcaatgact ttacgtgact
    27961 tgatacgaag agcaaaaaca gatcatcgta tcaaacaaaa agacgattat atctttgctt
    28021 ctctaaaaaa taaagcgtta gaactaattg aattgcaaat cagcgaagga atagataagc
    28081 aataagaata gaattgagtc aaatgaaatg gaggggtatc tccacttcat ttgagaactt
    28141 tgaatatagg aggggttatt ttgattaaaa atcgtttaat agatcaagtt tggtgtctag
    28201 atcaaaatac agatagtctc gaattaatcg agactatttg cttcaacact atagttctcg
    28261 atttaagagc tgaaaatgat aattgtgtaa ctcatgtcat aattaatcaa aaaatggctc
    28321 agaagctctc tgagagcctc agaaaatggg ctaagggagg taacgatgaa aataattgaa
    28381 aaaaagattg ccaataaaaa aataaattgg ttggttgtta attttcttgt tctgatagct
    28441 atgattattt ttacaagtaa tattgctcat gcgagtattt tcaattggtt tgatgacaca
    28501 aaaagtcaaa cagagttttt gaataattct ctttatagac cttacctaaa aaagtacaat
    28561 ggagatttcc ttagtcagtt cgggatttgg ctcggatggg ctgtggtaaa aggcatgttt
    28621 actgtgacag attcgattca aaatatgatt ccagatgtgc tggatttgtt caatttcatt
    28681 gaaagtacag ggctaaataa tgtttatcaa tcagccgtaa atacaattgt cattggatta
    28741 atgatccttt cattgatgtt tgttggttac aaaatgatta ctggaaaagg aacagtggat
    28801 ttaaaatcgg ttggaatgaa cgtagtgatg tctatagcat taatactttt aatgccaacc
    28861 atgatttcta gtggtattca atttgctaaa acattttata aggactctac tacgattaca
    28921 aattcagatg acggagtcgc ttggtcattg ataaaacaag gagtaacaga tttagcatat
    28981 attaataaaa cagatcagta ctcaagcatt gataaaacgg aggatcgaaa taatttaaca
    29041 cgaaaaaatt ttcaacagac ggatctcaca caagtgttaa cggataaagt gattgataaa
    29101 ttggaaaaag aaaatccaat tgcggacaat cttcgttatg aattagttga aaattctaat
    29161 aatgaatttg ttgctacaaa gttttctgac aacttcttat caacattttc tgatagcttg
    29221 aaatcaggct attaccgata ccaagcaaat ctatggggga tttcaattgg gttgacagcg
    29281 ttagcaatcg cctatgtgtt cagcgcgttt gtgatcatta cagcaatact agaacttgca
    29341 tttaaacgtg tgttaggtgt tcttgttttt gcaacagata ttgagacagg acagcgttca
    29401 aaagttgttc tatcagatat tctacaatgt tacttaactg ttgggtttca aggatttggg
    29461 ttatcaatgt ttgctatgtt tatcaatttt ctgaactcag gacaaggtat ctcaacaaat
    29521 atttttataa aaacaattgc ttatatctgt gccgtttttg ttttaatcaa aggcagtgga
    29581 acagtcatga gatactttgg tgttgatatt ggactcaaag aaggctatgg gcaacttgct
    29641 tctgcttttg gaatgggcgc aatgctgttt agaaaaggat caaatggatt taatcgtgct
    29701 aaaggaagcg gagaaggaga agatcgaaaa ccagaaaaga atttcggcga aactctatca
    29761 aaaaaagctg gcaaaactgg aagagctttg ggatatgccc atgaacgtgg attatccggt
    29821 ttagcttcag atggagctac aatggctagt gaaagagcaa caaaaccatt taagagtatg
    29881 cgtgatatag ctaatgatac caagaataag tttaaagaag gtttagatga tggtacagtg
    29941 tccgctatta ataaaaatag caaacctatg ttagctaaaa ataaagaaga tgaaactgga
    30001 aaatatgctg attccgtgcc aacacgtctt tcagatagaa aagatggtgc taaagttgaa
    30061 aatgccgata gaattatgtc tagttctgaa cgtatgcgtg aagcaatgaa aaataatgct
    30121 gaatcgaata ataatcctgc aagcgcaatt cagcaaaaag tccaacaaga tattgaagaa
    30181 cgtaaaaatg ctatgcacgg tcaagctaag tctgctgaag aattaattaa tcagaagcgt
    30241 catgaagcga aatacacgcc tgaagcaatg aatcgcgagg aaataatgtt aaggaaacgt
    30301 gtagaagggc ggacaggcgc taatattgac ggaaaagaag cgttgaccaa agaaagaatt
    30361 caagaagcta aaaattcaaa tacaggatta gaaaaattag tcaaagaaaa tccacaaaat
    30421 tctacaagta gtcatggtgg ccgatcagta gatgtccgag aaaatattca aggttcactg
    30481 aatggtcatg ttggacggaa tgttgatgta agagagaatt tacaaagttc ttcaaatgct
    30541 caaggtacta agacaattga tgttcgagaa aatctgcaaa gtagcagtac aagtcaacca
    30601 aaaacagtag atgttcgaga aaatgtacaa aattctacaa gtagtcaagg gtttaaatca
    30661 gtggatgtcc gagagaatgt gcaaggtagc agtgcaagtc aaccaaaaac agtagatgtc
    30721 cgagaaaatg tacaaagttc tacaagtagt caaggattca aaacagtaga tgttcgggag
    30781 aacattcaaa aagatagtgg agaaatgaaa gaaaaaacac aaaaaatcaa tatcgttgaa
    30841 gacagaaagt cagcgaaaaa atttgattca aatcatgaaa cagtgattat tgatagtgaa
    30901 atccgtgaaa atgataaggg atcaaaatca agacgaagat tcacttatga agacaatgag
    30961 ttattcagag atacacttaa tgatcctaat ccacttttcg ataatttatt aagaaataaa
    31021 agggggggat tgtcatgcaa ttaattctaa agattagtac gcatgatttc ttagaacttg
    31081 acgaattatg tgaatcagta aagaacgcaa caaatgaaaa aatcacggtc actaattata
    31141 ttgaactgat gattcaagaa gaattaaaga tgaaaaatga aatagagagc aatttcaaat
    31201 gttgctctct agaaaaaaat gtgaggggat aatcaatgga tgataaacaa aaaatgtacg
    31261 aaaaaaatcg caaacatagt gaggccttaa attttcgtgt cgataaaaag acttatcttg
    31321 aactgacatt gattgcaaaa caaaggggaa tttctagagc agacgtttgc cgtgagcggt
    31381 taaagggact caaatatgaa ccgccgttgt tagctgaaga tgatagggta gttttaacca
    31441 aacagttaaa tcaaattggt aacaatttga atcaagcggt aaaggcatta aatatcattg
    31501 ctaaatattt tagagaagaa tctgaagata aaaaagaaaa gagcctacat tttagttttg
    31561 atgctagccg ttacaacatt tttaaagatg aacttgcgaa tagcatagca aaaaagttga
    31621 tgattagtta tccagatgac atttttttgg agtccaatcg gagtgccccc tcttttttta
    31681 aattatcaga agtagaaaaa gaatatttcg aatattggat agaaaagcaa actagaccgg
    31741 gtacgaaaga agagtattcc caaaaagttg atcggaattt aattcactca attcagatta
    31801 ttgcaagttt aaaagatgag gtgaaacaac tttgggagct actataacat cgaaaggacg
    31861 caagaaaaat ttatcctcgc tattacaata tgcagctaat ccttcaaaaa aagaaaaatg
    31921 tgttgcagta tcaggaataa attgtagtga tgatagtgag gaagcactgc aagaaatgaa
    31981 tttagtacgt accaagatga ataaatctaa agatatagca caagcgtttc atgttattca
    32041 ttcgtttgat aagagtactt ctaaagagtt aagtattgat aaaatgcacg aaatagctgt
    32101 cgaatttgca gagaaagctt ttccaaattc gcaaatcatt gttgcaagtc acaatgataa
    32161 agatcatttt catagtcatc ttgtcattaa taatattaac atggaaacat gtaaaaggtt
    32221 gcgtattgac cctaaagatt tagaactaat gcgaaaaatt aacgatcaag tcctcaatga
    32281 acatggtctt gaatcagtga ataatgagta ctatgaaaac ttagaaaaga gaaccaatct
    32341 ttattcaaac gatccttcta agatgaaata tggaaaaatt aattatcaag agtttgtgca
    32401 aaatgcgatc gaagcaacgt tggaaaaatg cgaagtgaat tcttttgaag atttttcgga
    32461 tcatttggca aaagaatata acattgaagt ttatcaattt tcaaaaacaa ataacaaact
    32521 tggctatgtt ctttacaaac aaggtgtaaa tttctatgag cgtagaggtg agttaattac
    32581 tttaggaaga gataaacaat ctagaaaaga aaaaagtcag tatgtcgaac gtacttttag
    32641 tgcaagaaag ttagggaaaa gatattcatt tgaatctgtt tctgaacaac ttgaaaagaa
    32701 tttagaagaa tcacatataa aaaatttttt taatatggaa agagagcaag ttatgtcgct
    32761 aattagtgga gtaaattaca aaactggtga gttaaatgta ccgtttgtgg aattagattc
    32821 catcgcacaa aagcaattta gcgaccgtga aggcgatgaa aaattcatta aatatgatga
    32881 cttcttgcga gaggtagaca agcattttgt aaatacaatg tctttagaag atgatcaaga
    32941 atacacgatt aaacttcata cggatgtgaa tcctcaaact ttacgtagtg cgaaaagtaa
    33001 aacaatttct attaaaaaga ctgatcagaa agagttattt ctaccggcaa agggttttga
    33061 aaattgttct catacacctt ctgctaaaca gattcactat caaatcagtc gcataatgaa
    33121 tgacgatgta aaaatgtatc gtgctaaaaa ggattatgaa ttcacacaac aaatgattga
    33181 aaatcagcaa aaaaggcaac aaaattttga aatggaattc tgaatgggct tgttagtgga
    33241 ctttccagtt ttttgcctat gaagagttgc ttggaaagaa gcagttttta ggacatacgc
    33301 cagctaccca tctacttgcc agtcaatccg ccccgctcac gctaggctac tttctggcaa
    33361 gtcagatggc gggtaaatct ctgagggagc aagctcccta cagactccct cccaaaaaaa
    33421 gaaaggtgga agaaaaaaat gaactatcca tattttaaag tctcggcttc agaagaaact
    33481 aaagaaatat tcaacaattt ttacaaccaa aacaaaggaa tttttggttc aaaggcaaat
    33541 atgtttcgtg ttatggtttc aaatttacca gtgttagcta gtccatcaaa taataaattt
    33601 aatgatcctg aaagcattaa atttgaacaa aaaatttcag aactagaatc aatgataagt
    33661 aatgaagtaa ttgaaaagct ggatgacatt gatcaaaagt tatcgtattc tctaaaaaac
    33721 aaatacaaaa cggaggagaa aaaagatgtt taaagtttac ttcccgtttc agtggctcgt
    33781 taaaggaatt cttttagtgc tactaggatt gattcttttt ggaagttatc taacaattaa
    33841 agccagacat tttccagaag aaaagccaat aaaaattgta acaaaagatt taaaaatagg
    33901 tgaaacttat caggcagatg gggttgaact aacatttaaa aatattgaag tgaccgaaaa
    33961 aagaaatgaa tttgcacaac atgatcgtgt attacaagtg acctatacac ttataaatga
    34021 tacagaaaat ccgatacgtc cacaacaatg gtcgattgaa aataaggatg gtgaagaact
    34081 ttatgagtat gatatgatat tggataatcc agagtatatt gaaagtggca aagaagaaac
    34141 agtaaattac tattatgaat taccgattga aaggcaggac taccaaatcg tagtacgtag
    34201 agagaatggt tacatagttg ggttgccatt tactttataa gttttatttt gttagtagtt
    34261 tttaaggtaa tatcagtttt gtgatttttg aaaatggaac tgggagaatg gctgaggaaa
    34321 ataaagttgt tccgtttgaa acattagtga taaataagga agagtttgag caactttttc
    34381 ttgatttttt tattcaatat gacatgattt atgattttag ttcgtcacta gatttatttg
    34441 aattagaagc agaaataata gaaaacagtc gagagaagaa tggtaaaatc attatttcag
    34501 tagaaaaatt caatgaatta ttctcacaaa catttgaaat agatccagac tattatcaac
    34561 cacaagaagt ttttcgagag tttagaaata agattattgg ttttagtcaa actacaaaat
    34621 gaaagcttaa taaagcaagt gttgatagaa ttattcctca acgcttgctt tattttatgg
    34681 gcacttcata atagaggtat agagaagaga ggtattcatt ttggatacta ttactccaac
    34741 aaacttcaaa gaaaatatag gtaaagtgtt gcaagaagta gttcattcaa attctgaaat
    34801 agaaattact agggattcta aaaatggatt gaacgatggc gtcattatga tttctaagag
    34861 aaaatgggag ttgttacaag aagaacttta tttacaacga acgggtacat gggcttatgt
    34921 atctgattta
//
LOCUS       DAJSMK010000022        34374 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.022, whole genome shotgun sequence.
ACCESSION   DAJSMK010000022 DAJSMK010000000
VERSION     DAJSMK010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34374
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.022"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(27..1919)
                     /locus_tag="ON488_001061"
     CDS             complement(27..1919)
                     /locus_tag="ON488_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231270.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(1916..3643)
                     /locus_tag="ON488_001062"
     CDS             complement(1916..3643)
                     /locus_tag="ON488_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231271.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(3659..4309)
                     /locus_tag="ON488_001063"
     CDS             complement(3659..4309)
                     /locus_tag="ON488_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCR3231272.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4513..4809
                     /locus_tag="ON488_001064"
     CDS             4513..4809
                     /locus_tag="ON488_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCR3231273.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5001..5621
                     /locus_tag="ON488_001065"
     CDS             5001..5621
                     /locus_tag="ON488_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HCR3231274.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(5713..6879)
                     /locus_tag="ON488_001066"
     CDS             complement(5713..6879)
                     /locus_tag="ON488_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR3231275.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(6891..7244)
                     /locus_tag="ON488_001067"
     CDS             complement(6891..7244)
                     /locus_tag="ON488_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCR3231276.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7372..8394
                     /locus_tag="ON488_001068"
     CDS             7372..8394
                     /locus_tag="ON488_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HCR3231277.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            8413..8574
                     /locus_tag="ON488_001069"
     CDS             8413..8574
                     /locus_tag="ON488_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231278.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(8833..9267)
                     /locus_tag="ON488_001070"
     CDS             complement(8833..9267)
                     /locus_tag="ON488_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231279.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9377..11236)
                     /locus_tag="ON488_001071"
     CDS             complement(9377..11236)
                     /locus_tag="ON488_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCR3231280.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11354..12513)
                     /locus_tag="ON488_001072"
                     /pseudo
     CDS             complement(11354..12513)
                     /locus_tag="ON488_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(12820..14244)
                     /gene="araA"
                     /locus_tag="ON488_001073"
     CDS             complement(12820..14244)
                     /gene="araA"
                     /locus_tag="ON488_001073"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HCR3231281.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14260..14958)
                     /locus_tag="ON488_001074"
     CDS             complement(14260..14958)
                     /locus_tag="ON488_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCR3231282.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(14915..16576)
                     /locus_tag="ON488_001075"
     CDS             complement(14915..16576)
                     /locus_tag="ON488_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HCR3231283.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            16794..18194
                     /locus_tag="ON488_001076"
     CDS             16794..18194
                     /locus_tag="ON488_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HCR3231284.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18446..19525)
                     /locus_tag="ON488_001077"
     CDS             complement(18446..19525)
                     /locus_tag="ON488_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3231285.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(19611..20570)
                     /locus_tag="ON488_001078"
     CDS             complement(19611..20570)
                     /locus_tag="ON488_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HCR3231286.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20582..22093)
                     /locus_tag="ON488_001079"
     CDS             complement(20582..22093)
                     /locus_tag="ON488_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCR3231287.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22115..22678)
                     /locus_tag="ON488_001080"
     CDS             complement(22115..22678)
                     /locus_tag="ON488_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HCR3231288.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(22684..23547)
                     /locus_tag="ON488_001081"
     CDS             complement(22684..23547)
                     /locus_tag="ON488_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3231289.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23561..24457)
                     /locus_tag="ON488_001082"
     CDS             complement(23561..24457)
                     /locus_tag="ON488_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3231290.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(24632..25921)
                     /locus_tag="ON488_001083"
     CDS             complement(24632..25921)
                     /locus_tag="ON488_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3231291.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(25893..27410)
                     /locus_tag="ON488_001084"
     CDS             complement(25893..27410)
                     /locus_tag="ON488_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HCR3231292.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            27608..28498
                     /locus_tag="ON488_001085"
     CDS             27608..28498
                     /locus_tag="ON488_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HCR3231293.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28571..29395)
                     /gene="nadE"
                     /locus_tag="ON488_001086"
     CDS             complement(28571..29395)
                     /gene="nadE"
                     /locus_tag="ON488_001086"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HCR3231294.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29407..30879)
                     /locus_tag="ON488_001087"
     CDS             complement(29407..30879)
                     /locus_tag="ON488_001087"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HCR3231295.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31516..31878)
                     /locus_tag="ON488_001088"
     CDS             complement(31516..31878)
                     /locus_tag="ON488_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCR3231296.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32101..32853
                     /locus_tag="ON488_001089"
     CDS             32101..32853
                     /locus_tag="ON488_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCR3231297.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(32993..33916)
                     /locus_tag="ON488_001090"
     CDS             complement(32993..33916)
                     /locus_tag="ON488_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3231298.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(33931..34203)
                     /locus_tag="ON488_001091"
     CDS             complement(33931..34203)
                     /locus_tag="ON488_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231299.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10145 a         7158 c         5909 g        11162 t
ORIGIN      
        1 aaaaaaaata ataaatttgt actattctat gaagcttctt cttcagaaaa ctgactgtta
       61 taaagatctg catagaatcc gtctttttcc atcaatgtat cgtggtttcc tgtttctacg
      121 atcgaaccat gattcatcac aataatgttg tctgcatcgc gtattgtaga caagcggtga
      181 gcaacaacga aacttgtccg gttttccaat aggcggttca tcgctttttg aatcagtatt
      241 tctgttcgtg tatctacact agatgttgct tcatcaagga tcaggacatc tggatttgct
      301 aagaatgccc gcgcaattgt gattagctga cgctgccctt gcgaaatatt gcttgcatcc
      361 tcgtttaata cagtgttata tccttctggc aatttacgaa caaaatcgtc tacgtgagca
      421 gctttagcag cctcaatgat ttgttcgtct gttgcatcgt cgttcccata tttgatattg
      481 tcatagatac ttcctgtaaa cagccaagta tcttgcagta ccattgaaaa ctgtgcgcgc
      541 aattcatcac gtgaaagatc acgggtatct acaccatcgt aacgaatact acctccagaa
      601 acatcgtaga accgttcaag aaggttgatc agtgtcgtct tccctgcacc agtcggacct
      661 acaatagcga ccatctcacc aggtttgaca tccaagttaa aatcagtcat tagcaagtta
      721 tctggtgtgt agccgaattg aacattttca aaacgaactt tgtatggtgt atctttttct
      781 tctggaaggc cagatttttc attggacatc tcttcttcat ccaacacttc aaatacccgt
      841 tcggctgaag caactgttga ttggatagtg ttcatcaaac ttgcaagttg agtgattggt
      901 tgagagaact gtgttgtata ttgcaagaac gcttgaacat cccctaatgt catgttccca
      961 tttgcaactt ttactccgcc tagtacagcg acgaacacat agcctagatt tttaacgaaa
     1021 ttcatcaacg gcatgatgat tgccgaaata aattgagctt tccaaccagc ggcatacaga
     1081 ttctgatttt ctttttcaaa tacttcctgg tctttttcag tatgattgaa tgttttaaca
     1141 atggtatgac caccatatgt ttcttctact tggttattca ataaacctaa acttttttgc
     1201 tgatctgcga aaaacacttg tgatttcggc gctacgatca tcacgatgat caagcttaaa
     1261 gggatcatca ataacgcgac taacgtcaat tgccagctga ttgaaagcat catcacgatg
     1321 accccaatca atgtgactgc actagttaca aattgagtca aattttgctg cagcgtgctt
     1381 gcgatgttat ccatatcatt gattgctcga gacatgatat ccccatttgt atgtgtatca
     1441 taataggaaa tcggtacacg attcattttg gcttccaaat catgacgtaa ttcataaact
     1501 gttcgttggg aaacacgtgt cataataaat tgctgtaaaa agttgaatac agcagaaatc
     1561 aaatacatca cgattactgt cgcaatgatc tgcgcgattt tatcaaagtc tatcggaaat
     1621 tttgttactt gttggccttg ttgcatctgt tgagcgccag ccattacacc tttgaatatt
     1681 tctgtggttg ctttccccaa gacctttggt gtttggattt ggaagatcac ggctgctatt
     1741 gctagtacaa atacagcgat gatcgcaacc atacgtttag acatatagcc aaacaatcgg
     1801 cgtaccgttc cccagaaatt tttaggcttt tcacctttta caccgagatt tctgccaggt
     1861 ccaccatgtc ctggaccgcc tgctggtcca tgagagggac gtgtgtttgt tttactcatg
     1921 ctaagtcctc ctctcttagt tgtgaatgaa cgatttcttg ataagtttcg tttgttgcta
     1981 atagttcttc atgtgttcct ttgccaacca gttttccttc atctagcaca aggatcatat
     2041 ctgcatccat tactgtactt actcgttgag caactaaaac ggtgatactt tctttcatat
     2101 tcgttttcaa tgcttggcga agattggcat ccgttttgaa atccaacgct gagaaggaat
     2161 catcaaacac atagatatct gctgttttga ctaatgcccg tgcaattgcc agacgctgtc
     2221 tttgtccacc agagaagttt cctcctcctt gttccacatg gctatctaag ccatcttcca
     2281 tctctgaaac aaaatcttta gcttgtgcga tttctaatgc tttccaaatc atttcatctg
     2341 ttgcatccgg cttaccatac tgcatattgt ctcggatcgt tccagagaac agaactgctt
     2401 tttgaggaac aaagcccatt aattctcgca aattatattg agtcatgtca ctaatgtccg
     2461 ttccatttat ttggatcgaa ccagattcga tgtcatataa tcgagggatc aaattgacta
     2521 aggtcgtttt acctgaacca gtccccccta tgattgcgac gatctcgccc gacttggctt
     2581 ggaaatcaat atcttccaat gcaagttttt ctgctccatg atatcgataa ttgacatgat
     2641 tgaaggccaa tgttgcgttt tttccagcaa aagaaactgt tttaggattt tcagggtcat
     2701 ggataccgat tttttcatcc aacacttcat taatacggtc agctgaagct tgtgcacgag
     2761 gcaccatgat aaaaatagcg gaaagcatca taaagctgat caagatctgc atcgcataag
     2821 tcataaatgc aatcagatta ccgacttcca aagtcatatc tgctatgtag tgtccaccaa
     2881 accaagtgat tgctacgttt gtaccgctca tgatcaatgt catcattggc atcatcaatg
     2941 cgacgatcgt attaactttg attgccgtat ttgtataatc tttattcgct aaatcaaaac
     3001 gattttcttc aaagcgtgtc ttatcgaatg ctcgaatcac tctgacccct gtcaatcctt
     3061 ctcgaaatac caggtttaaa cggtcagttt tcttttgcat acttttgaat aatggaacag
     3121 caaagtacat gattccgccg atcaaaataa tcattactgg gatgacaact aagaagattt
     3181 ttgtcaactg atgatctttt tgataagcaa gtatgctcgc gccaatcaac gtgattggtg
     3241 cattgatcat catacgtaaa aacatttgtg taaccatttg gatttgagtc acatcattgg
     3301 tcgttcttgt gatcaaagag gccgttccat atttatcaaa cgcatctttt gtcagactct
     3361 ctgatttttt atagacatcc gtacgcaatt gcttacccag tttctgtgat tcacgagtag
     3421 caaaaaatgt atttgcgata gcagctaaga tactgatcaa agaaaagccg atcatcacaa
     3481 aacctgtatg ccaaatataa tcgacatctc cttgcgctac ccctttatca ataatattgg
     3541 aggtaagtgt cggcaaatat aaatctgcca gtacttggat caccatgaaa actgcagctg
     3601 caattgctga agtcaaggag atccgtttta cgatttttag catctagttc ccttctttct
     3661 atttatatac tccgtttttc agccaagaaa gtttcaaatt gaattcactg attgcttgct
     3721 ctactgagta atcttcagat gttgaaaata agcgatacga atgcgcaatt gttgtaaata
     3781 cagtattcat cactaattgg atcagtaatt ccaattcatg atcatttttt actttcagct
     3841 tcgtccgatc gatcaattca agcaactctt ttgcatcttg tttgtgttct ttatgtggat
     3901 cgtgaggcgt tttttggcga ctcgtatgag gagcgacttt tcttgaggca cggtaatcca
     3961 tgttcataaa caagttacga taaaaagaag cattctcgcc ttccaaaatc tcataaatca
     4021 ttttagaaaa ataggattcg aatcctttga atagatcacc atcggattct ttcattagtt
     4081 gtaacatatc tttagagctg tcacgtctca ttgtctcaaa gtaataaaaa taaagatcct
     4141 ctttatcttc aaaatactga tagaaactgc ctctagggat atccgctaat ttgacgatat
     4201 tagcaatcga agcttctttt aagggtactc tagaaaactc gattctcgca gcctcgatta
     4261 gtcttttttg tttttcttta ggcaaatgga aaaatgtctg tgtcggcata tggattctcc
     4321 tttctttcaa gatgacacat tgtcatatga cgctatgtca ttataacacc tcctacctgt
     4381 tttgcaagac atttgcatag tttttttcat tatcatccga tacattaaaa aagtgataag
     4441 aggaatcctt ccatttgaat taatgagagt tgcccattaa aatagccaca tactaaacaa
     4501 aggatgagat aaatggccca atcaattagt gtccaagact tcaataaatt gcctctcgat
     4561 gctgacagca tcgttttaga tacaagaaat accttagatt acacaaaaaa ccacttaagc
     4621 cactcgcttt ctatccccgc tgctatcttg ccaagacaat taaaaaatct agatccaaag
     4681 aaactttatt atattctaag ctatacaggc aggcgatcag aagcattagc cgatcaactt
     4741 actgctaatg gttttcgtgc tgtttatatc attggtggga tggaagctct tcagtcgagt
     4801 gttgcttgaa tattgcttgt tagattcaaa agaggctgtg acaaaaaatc gtgtcacagc
     4861 ctcttttata ccctgtcttt ttttagttat ttattcttca accttatcaa tatgacttga
     4921 tagccttttc tttttcgagt aaactgattt tgttagtcat agttataaca atcatagcaa
     4981 taaaaggaga aggtaagcat atggcatctg ttttagtagt caaaggtcat cccctaactg
     5041 cagaagaatc gcgcacagtt aaggcattga cgtctttttt aacaagttat aaagaaaatc
     5101 atccagatga tgaagtgact gttttggaac tttatcgcga tgatattccg gaaatcgatg
     5161 aagaattatt atcaggttgg gaagcattac gtgctggtgc agaattcact tccttatcag
     5221 aaagtcaaca acaaaaaatt gctcgtttca atgaattgac tgatcagttc cttgctgctg
     5281 ataaaatcgt tatcgcaaac gccttatgga atctaaatat cccaacaaaa ttaaaagctt
     5341 ggttcgatac cgtcaatgta gctggaaaaa cgttccgcta tacagaaaac gggccagaag
     5401 gattagtgac aggtaaaaaa gcactgcaca tccaatctaa tggcggtgta tacaacggac
     5461 aagactttgc ctctcaatat gtaaaaggta ttttaaactt tgtaggcatc gatcaagtag
     5521 atcagctatt catcgaagga atcgattatg accctgaccg tgcagatgag ttgatgcaaa
     5581 atgcattaga taaagctgct gctttaggta aatcatttta aaaattgaga taaatgcata
     5641 caaaagagac agaggaaaaa atcttcaaag cagcatttgt gccttggata ttttcccatc
     5701 tgtctctttt tgttattctt tctgcttttt caacggattt tcttcataaa gagaagagat
     5761 tgttgtgtac cattcaaaaa catgagtaat cactacttta gctgctgcat aaacaggaat
     5821 ccccaagatc acaccgatga ttccgaacaa tttcccagaa gtcagcagaa ctaataaaat
     5881 cgttactgga tggattgcta actgattccc tagtactaat ggagagatca agcgtccttc
     5941 tattgtctgc tctactgcaa aaacgatcag tactttgatg atcatgaatg gacctgctac
     6001 aatggctaaa aagatagccg gaatcatcgc taaaaatgat cctaagtaag ggatcaggtt
     6061 taaaaaaccc gcaataatcc ccaacgtgac agcatactct aaaccaatga ccgcaaaacc
     6121 aatcataaac atgattgcca cagcaaaagc cacagttagt tgtcctctta tataagaaga
     6181 aacttgacta ttcatttcac tcagcacatt caacgtcggt ttttgcatgc gtgtcggtaa
     6241 aaatttgaca aaataaggtg ctaattgttt accgtctttc aatagataaa ataagataaa
     6301 cggcatcgtc agcagagcca ctaaaatagt cgctaccgcg ccgacaaaac ttccaagact
     6361 ctgaactgta ctcttagata tatcttggat catatcgcct gccgaattca tgaacttatc
     6421 acctgctgtt tccaactgtt cgcgaaattg gttgaacagc gggtcccgca aaatctcggt
     6481 taatttatta tcaatcgtat ctacatattg agggaagtta ctgatgaagc tcactgtttg
     6541 ttcctgaatc ttagggatga tcactacgct cccccatgcg attagtgcaa caaccaaaac
     6601 aaacagccca atgatactgt aaagccttgg tacttttcgc ttttcaaagt aatcaactac
     6661 cggattcatc aagtaataca agattcctgc taaaatgata ggcagaccta cgattgctaa
     6721 aaattgccag attggtgcaa acaaatatga aacttttgta aataaaaaga cgatcagcaa
     6781 tattaacaat acaacaagta aggctgtgac tacttgatta tttaaaaacc agcgccaaaa
     6841 ccacgatacc ggtctgttct tcttattttt tccttccata attcctcctg ttagttataa
     6901 aaaatttggc ttcccaaacc aatagcaggc agtctatgcg gatgaagata gattccattt
     6961 gcaatttgtc cttcttctgg acaagcatca aaaatcaatg atacgtgagc tactgtcttt
     7021 aaattcccat tggccatcgg accgacataa tcgatcgtat atacctgatc atcaaaagca
     7081 attgttccgc ctgctttcaa agaaaaaggt tcgtcttttg atacttcttg aatcaccgaa
     7141 tattttcgta aggcagctgt tgctgtttta tcgaacaaaa tcagcatggg ttcttccttg
     7201 tttattgctt ctgtcccaat ttctgtaatc tttgcctgaa tcattgcact ctctccttta
     7261 attgctttca aaaacagtat aacacattct cattctttag ccgtgtggaa taattatgtg
     7321 atagaataaa aacgaaaact atttcattac aattaggagg aatcagctca tatgatcgaa
     7381 aagataattt taggaaccta tacgcgtcgc gaaagtaaag gaatctatac gatcgacctt
     7441 gatacagaaa aagaagaatt agccaacctt tcattagctg ttgaagaaaa tagccctacc
     7501 tatgtagcaa aaagtaaagc tggcaatctt tacacagtta ctagtgtgga tggattaggt
     7561 ggtgccggtg cgtacgataa ggattttcat tttttgaatg cggtaacaga gtctggcgct
     7621 cctttgtgtt atgtagcggt tgatgaagca cgtcaattac tatacggggc gaactatcat
     7681 aaaggtgaag taaatgtcta ccatatatta ggagatggcg aactgaaagc agcagattca
     7741 atattccatc aagaagcgac aggtcctcat aaaaaccaag atcatgcgca tgtccactat
     7801 acggatctga ctcctgacca acgattagtc gtatgtgatc ttggtacaga tcgtgtgtat
     7861 acttatgatg tgtccgaaaa cggcaaattg aatcttgtaa ctaccttcac tgcagagcca
     7921 ggaacaggcc ctcgccatct tgtctttcat ccaaatggac aattcgctta tttatttggt
     7981 gaattagaca gcacagtccg cgtgctttct tataataaag aaacaggtgc ttttgaagaa
     8041 ttacagaaaa tatcgacctt gccagaagaa ttcgacggtg aaaatggagg ggcagctatc
     8101 cgcatttcaa atgatggcaa gttcctttat gcttctaacc gaggacataa ctcgattgct
     8161 gtattcgcag tttttgaaga tggttcccac attcaaaaca agcaaatcat ctcaacagaa
     8221 ggggattttc cccgcgattt cgcactagat ccaagcaata attttgtcgt gtgtgccaat
     8281 cagaacaccg ataatctgac attatatcgc cgtcatcctg aaacaggatt actggaatta
     8341 ctgaaaaaag atgtctatgt accagaatgt gtctgtgttt attttgatcg ttagtaagaa
     8401 aaggagaatg aaatgaatca gcaagacgta ttagacagac tacgggaaga actaaatatt
     8461 cctttctttg atgggaaaat cgaagataaa gagtatagcg aagaggaata tcagaaactc
     8521 aaagccgatt tacagaacta ctttgaacaa tatgtacaga atgtagaaaa ctaatcagct
     8581 ttccatacta tctgaaaaga acatcaggac aagacttttc cgtctatcct gatgttcttt
     8641 tctacaaata aaaaaccgcc gagatggtta gactcgacgg aaaaggagta tttactcgat
     8701 tttgagtaag tacaaggttg ttgttggtta taggtatgtc attatcataa aggattttga
     8761 tcactctatc ataaaggtaa tattacattt atattagata actctagttt ttattgttat
     8821 caaagatttc ttttattttt tcaacaacaa attagtcatt ttttggatgg cagctgtcaa
     8881 ttggtctgtc gcttggtctt gttttgcttc agatgtattg aatagatctt catctacccc
     8941 tgattcaaga tcgatacttt ggatcatttc ttcacagcct gctacatatg aaagataagc
     9001 tttttcaaaa tttttatgaa tgcccattgc ttttgctggt ggacgcaaag tactgacttt
     9061 cataagcatt gcccgatatt tttttgttcc ttcttcaaat aacaggatga tctcttcaag
     9121 agtcgatttg tccagttcac ttgtttttcc ttcatcaatt gcgtttctga tcacttcata
     9181 tttcggatgc attccttctc cgattgcttc tgtttccttg acgatttgat cgatggactg
     9241 cacataatag ccaatattcg gtaacatgtt cgttttccta ctttctccat tgttgttatt
     9301 atttattcta cttgttttta tcctcaaatg acaagtactt gaaaaaattt aatggtttct
     9361 atacagctcg ccattcttat tcgtgctcaa agaaaccatc tgctaaacta tattgtttcc
     9421 ctgcgacaat gtcatattgg atcaattgat attcgtcgta aatctcttgt tgcgagcgat
     9481 tgaattgcgc ttctttatac cactgtccgt tttgatagta cagttctcgt tcaaacgccg
     9541 gaagttcctg ttctaatgat aaaagcagct gataaaagcc atttgttgtc tgattcgtct
     9601 gttccattag attcgctgca aaataaaacg gactggtgat tgcatcgtga gtcgtttgct
     9661 tttctaattc tcctttactg tcgaacataa gaaattgtgt ttcatgcaat gtttgtttgt
     9721 cattttttgc ttggatcgta tctgaataga tccctggaag atgatccccc caaaaaacaa
     9781 ctaaagtcct tctagaaaga ttcttcaatt cttccgtgaa ctgcttcagt gccgtgctgc
     9841 tataggaaat atcttgcaga taattctcta agtcaagtgt cccacttcca tctgaagttt
     9901 ttgcaggata gtctagatta tcatactttc catcgtaggg catatgtgtc tgcatcgtga
     9961 ctaaatgaat gaactgaggt gttttttctt ccttgagaag tgtcattact tctttgtaag
    10021 ctgactcatc agaaatatat ggattattct ctatcgtatc cgtataggtc atcgtacgct
    10081 cgctgatgaa ctggtcaaat cctaatgtct gataaacatc ctctctttta tacatcgaag
    10141 tattgtatgg atggatcgct gtcgtctggt atgattgtgc gtttaacgct gaaacgatag
    10201 aaggaagctg atccattttt ggtacaagca tcgtgtaagg ggtggtgagt tgcgcattaa
    10261 ataacgccat agaaaaacca gtcaatgctt caaattcgat atttgctgtt ccaccgccat
    10321 agttttgaga aagcatattg ccactatatg tttgatcagc tacttcataa taatctgcca
    10381 atggctcacc agatacttct acgccgttta atcgactagg atctgagaaa ctttcactca
    10441 tcacgaacac gatgttcggc gactcttcct ctacagtttt atttttttca tcggctagct
    10501 tctggtattt ttcagtgatt tctttgatct tttctttcga atatccttca ggttcatcca
    10561 ttggttctac cttcagattg tacaaaaacc caccgataaa accagtgtta tagtagttca
    10621 ttttctggct gtaaggtatc catagtgccg ttttattata tgcttttcgc aacaaattat
    10681 cgggattgtt gaaattactg atatacccta gcagtccaat tgccacaagc agtgtcgtta
    10741 atcggatcaa ttggaatcgc cttccttttt tcaggcttcg aaacatgtac cagcaaaaca
    10801 atcctatcac ggttcctgcg gcagctaaga tcactgtaaa cagcatagtg ccggtcatat
    10861 ctttcagcaa tccgatttca gtgatcatct tcaaatcgtc tggataaatc ggttcttgcc
    10921 gataactcat tttcatataa tttgcaaaac ctaatacacc gatggctacg acatacgtaa
    10981 gggaacctaa agggacagat cctgctagtg caatcagaaa aataagaata atcagcaaga
    11041 cgagacaggc taagaagaat ttttccgtat gccaagaaaa agcaaatttc aacgcaaggt
    11101 ctacggatag atcattttga caccactgca aaaataaatt actaaaaaca acaagaaaaa
    11161 agatactgat gattgctgct gttcctttta aaatcttttt ctgtttggtc gaaagtctgc
    11221 ttatatatct tttcaaatgc ttgctccttc atttctatca ataaaagaat gttgcttctc
    11281 ttattttagt tgtacgaaat tcgaaagtaa agaacggaaa gaagaattaa tgaaatccaa
    11341 atattctctt tctttatggc ctttctggtt tctttaataa gcggaccttt cgtactccag
    11401 aaattttttc tagctgttgt ttcacttgat tgagctgttc aaaatcagta ctgtctatgt
    11461 caatcaatat gtagacatgc tcattcttat ggttacgcga tatatctgcg atcgctagct
    11521 cgttctcatt cagcagagaa aatatctctg ctaatatatt ggttttcttt tgataaaata
    11581 tagtgaatcg aaacggcgct tggaaaaaca ttcgtgcgga tggataattg accgcttctc
    11641 taaccgtacc gaacaaaaga taatctttta aggcttcaac tgccaaacgt ccgctgtctg
    11701 ccaaagcttc ctgagtcgat cccctagatg aggcaacata agtatacggt cattttctaa
    11761 gaactcttct tctggaaaat cagtcaagta tttagccaga tgttgttttt ccaatgcttg
    11821 cataacagca tatttatcaa caatttcact tcttcctaca ttgataagta cagcatcttt
    11881 tttcattttt tctatattcg cctgatcgat caatcctttt gtatcttctg tcaacggcag
    11941 catgactacg atgtaatccg aggtagaaag aactgtttct aaatctgctt gccgaacata
    12001 atccaactgg gcatcgcgga tagaataacc caagacatcc atccctaagc tatagcaact
    12061 tagcgctact tttgtgccta tcgctccaag accaagaaga ccgatggttt tgccttgcaa
    12121 ttctcgtccc acataagcac ttcttttgtt ttctgcctgt tctaaaatat taggacctgt
    12181 tagtgtttgt accatacgac ttgcttcgat tatcggacgg gaagataaga gcaaacagca
    12241 caaaacaagc tcttttactg cattagcatt tacacctggt gtattcatga cgatcgtccc
    12301 gttttcagaa gctttttcaa cgttgatcgt gttcacccca acaccagctc ttgaaattgc
    12361 tagcaaatct ggtgtaagcc attcatcttt cactttcgta ctacgaataa ctattccttc
    12421 ggctggcaaa tcatctatta ttttgaaata ttccccttgt aacttttcta tctcttgttc
    12481 tggaatagca tcaatcaaat gaacgtgata cataaaaccc cctccttact aacaagtatc
    12541 tcgaaatttc tgcaattaga caactgttta ccatttgact tcctagaagc aaaaagagca
    12601 gttagagcag agtaggctga gtgataaaaa taaggctatg acaagttact gccataagcc
    12661 ttattttcga gagcaaaata ttgagggtga gatatcttga taaatggtgt tccgttagct
    12721 gacattgata ataagactaa atttcaaaaa agttgaaaag caaatttcgt caatctcttc
    12781 ttatttctta aaactaagtg gctttttcac aacctctttt tatctaataa ccactgtttc
    12841 caactcaact aattttgccc acgtttcaat ttgatctgtt gttagattta gcgagacaac
    12901 ggtatgatga ccgccacctg cctgaatcca tgaatggaca ccttcatgga aattcggttt
    12961 agttttccat aacacacgtg caacaggtaa attaggtgct tcagtcgttg gttcaaaggc
    13021 ttctacttca ttgatcagca gtttataatg cgtaccgaaa tctgccatcg atacgactac
    13081 cccttctcct gctttcccat caaatacaag acgcgccgga tcttctctat ctcccattga
    13141 taaaggagaa acaacgattc ttggtttcgt cgcagcaagc gtcggatcta cttccatcat
    13201 atgggattcc aagattgctt cttggccact agctagctcg taagtataat cttccatgaa
    13261 tcctgtatct ttccctcgag ccatgatttt cagcaaccga tcaatcgctg cagttttcca
    13321 gtcgccttcc ccagcaaaac cgtatccttc tgccatcaaa cgttgtacag ctagtccagg
    13381 tagttgtttc attccataca ggtcttcaaa attagtcgta aaagcgttat agcctccttc
    13441 ttctaagaaa cggcgaatac cgatttcctg ctgagcttgt acttttacat gttcctccca
    13501 tgtcttttct tcataatcac catagtcgaa ggtatacaat tccttgtact cttcaaataa
    13561 ttgatcgact tcttcgtctg atacgcgatc gattacttgt acaagatctc cgataccaaa
    13621 ataatcaaca gtccaaccaa attgaatctg tgcttccact ttgtctcctt ctgtgacacc
    13681 cacgtttctc atgttgtcac caaaacgagc cacttttatt ccaaaacttt cattataggc
    13741 tactgcaaca tccatccaat cagcaatctc tttttggatc tcaggtcgtt tccagtagcc
    13801 aacgacgatt ttattttgtt tatttaatcg agcattgatg aacccatatt cgcggtcacc
    13861 atgagcggat tgatttaaat tcatgaaatc catatcgatc gttttccaag gaatgctttc
    13921 gttatattgc gtagctaaat gaagcaatgg tttttgtaga agctttgtcc cgcggatcca
    13981 catttttgct ggtgagaaag tatgcatcca agtgatcaca cctgctactt cttctcgata
    14041 attgacctct ttcatgattt ttgtgatcgt atcagcagta actgctaatt cttgaaggcg
    14101 gattggataa ggcaattggc cattttcatt cagttcatcg accatttctt gtgcatgttt
    14161 ctttacttct cgcagtgctt cttccccata taaatgctgt gatcctacaa caaaccaaaa
    14221 ttctttttct ccaatattca acataattag ccactccttt tatttgtttt gtccgtaata
    14281 cgcatttttt ccgtgttttc gtaaataatg tttatctaaa atccgttgag gcagctcttc
    14341 tgaaaatgaa ttgagctgtc tggtaaataa attcatcttg catacttcat ctagtacgac
    14401 tgcgttcatt accgcacttt gcgcatcttt cccccaagta aatggaccgt gtccgtgtaa
    14461 aagtacccct ggaattgcta agggatcaat tttgcgttct ttgaatgttt ctatgataac
    14521 ttttcctgtt tcatattcgt acccgctgtc gatttcctgt tgtgtcaaaa atcgagcaca
    14581 aggtaccgat ccataaaaag tatctgcatg cgtcgtcccc atcgcaggaa catccaatcc
    14641 tgcttgtgcc cagatcgtcg cccatgtcga gtgagtatgg acgattcctc cgatttgagg
    14701 aaatgaacga tataaaacag catgagtagg cgtatccgaa gagggattga gtttaccttc
    14761 aatgatatga ttgtccaagt ccacaacgac catgtcgtct gctgtcatct cttcataact
    14821 gactccgcta ggtttgataa cgaaatatcg tgtttcagga tcaaaagcgc tcacatttcc
    14881 ccatgtatat ttgacgagtc cgtgtttagg caagtcaaga tttgcttggt atacttcttc
    14941 tttcagttgt tccagcattt tctatcactc ctttttcttg caattgatga atcgctgttt
    15001 tttcaatgtc gatcccctca cggtaacgtc tcataaatat ctgatagcct gctatttctt
    15061 ctgctgaagg tgtgatggtg attccttggt cttgtccaaa cacgtcttct gccaagaagt
    15121 tttctaaaga cttcccatgt cgatccatca tataggctgc taataacgcg attccccacg
    15181 ctccaccttc tccggctgtg tccatcactg taactggtgc ctccatagca gatgctagaa
    15241 tccgctgtcc aacttctggt gttttaaaaa tccccccatg ccccactaaa cgatcaattt
    15301 ggacattctc agatttcaat atatccattc cgattctcat tgcaccaaaa gcactggcta
    15361 aatggatccg catgaaattc gctaaatcaa aacggctacc tggtgtacgt acaaataatg
    15421 gccttccttc atttactcct gtaatgtttt caccggaaaa ataaccataa gaaagtaatc
    15481 ccccgcaatc cgtatcgcct tctagcgctt tgttgaataa taccgtgaat aatttatctc
    15541 tgcttatctc catacccaaa gaattggtaa attcttcaaa aatactgacc caagcattga
    15601 tatccgaaga gcagttattc gtatgaacca tgcctactag ttctcctgaa ggtgtagtga
    15661 ccatgtcgat ttccggatgg acattttcta gttctttttc taatacgatc atagcgaagg
    15721 cggaagtacc agccgaaatg ttccctgtcc ctttggctac actgttcgta gcgaccatac
    15781 cggttcctgc atccccttct ggcggacaaa ccgggattcc tggtctcaaa tttcccgtag
    15841 ggtcgatcag ataagcccct gattcgctta acttgccagc ttcttctcct gctactagaa
    15901 ctttaggcaa aatgtgatcc aagtcaatcg ctacgtgcgc tttttcgatt aactgaccaa
    15961 aaatattttt catttcttga tggtaggttt tcgttgaagg atcgatagga aacatgcctg
    16021 atgcatctcc tacgcctagt actttctcac cagtaagctg ccaatggaca taacctgcaa
    16081 gcgttgtcaa aaaattaatt tctttcacat gttcttcttt attcaaaata gattgataca
    16141 aatgagcgat actccatctc tgcggaatat tgtattgaaa tttttccgtt aatattcgtt
    16201 ctgcttcttc agtgattgta tttcgccaag tacgaaatgg tactagtaac tgttccttgc
    16261 tatcaaatgc tagataaccg tgcatcattg cactgaaccc aatcgacccg attgtcgtaa
    16321 gattctcgcc atagatttcg aatacttctg ctgccatttt tcggtaactg acgcgcagtc
    16381 ctttccaaat atcttctaat gaataggtcc agataccatt ttctagtttg ttttcccact
    16441 cataactacc agcggcaata ggagtaaaag atgaatcaat caatacagct ttgatcctag
    16501 ttgatccaaa ctcaatccct aaagatgtac gaccatctat gacatctaac atactttgcg
    16561 catttacttc cttcataatg atttaactcc ctccttctcg tcaaacctga tcaaaccgtc
    16621 tttttagtag cgcttacaat gattattgta tacttttgta cgtacatgtc aagcagttat
    16681 ttacaagaat acaataaaaa acacttgttt tgtacgtaca taagttataa aatgaaattg
    16741 cttacaaaat ctgatcaacc gccttctcga aattctagaa ggagagaata cttatgaaaa
    16801 aagaaaaaaa agtttcctca tcgtttattt atttttttgg cgcatttggc ggcattctat
    16861 ttggatatga tattggtgtt atgaccggcg ccttaccttt tttacagcat gattggggtt
    16921 tggcaggtaa agcttctttg ataggatgga tcacgtcttc ggtcatgtta ggtgcgatcc
    16981 ttggcggctc tttatctggt cttctttctg ataagcttgg acgacgaaaa atgattcttc
    17041 tttctgcact tatttttatg gctggttctg tcctttctgc atctgcccct cacaatggtt
    17101 cttattttct gattgcagca aggattcttc taggtttagc tgttggcgct gcatctgccc
    17161 tagttcctgc ttatatgtct gaaatggctc ctgctagact aaggggaaga ttgtcaggga
    17221 tcaatcaagt gatgattgct tctggcatgc tcctttccta tgttgcagat tatttgctaa
    17281 aagggttgcc tgaaacgatg gcttggcgcg tgatgttagg gctcgctgct gtccccgcgc
    17341 tgattttatt tttcggtgtt ttagctctac cagagtcacc gcgttttctt atgcaatctg
    17401 gccgcttgga agaggcaaaa agagtattga actatattcg gacaccaaaa gaagctgaac
    17461 aggaattcga acaaatccag ctgaatgtca aacaagaaaa gacaaccgga acttcttggc
    17521 atactttgtt tttagaaaaa tatcgttcct tagtcattgc cggtattggt gtagcagtat
    17581 tccagcaatt tcaaggagct aatgctattt tttactatat tccgctgatc gtagaaaaag
    17641 cgactgggca tgcagcgagc gatgcattga tgtggccgat catccaagga atcattttag
    17701 ttgctggttc tttgctcttt ttggttattg cagacaagtt caatcggcga actttattga
    17761 aaataggcgg tagcgtgatg ggactttctt tcatcctacc agctgtttta ggaactgtac
    17821 tggatgctca tacaaattcg ttgttgattc tcttgttttt atgtatttat gtcgcatttt
    17881 attcttgcac atgggctcca ctgacatggg taatcgtagg cgaaatattc ccactagctg
    17941 tccgcgggcg agcatctggc ctagcctctt cttttaattg gattggttct ttcctagttg
    18001 gcttgctttt tcctgtgatg actgcttcta tgtctcaaga aatcgttttc ggcatttttg
    18061 ggatcatctg ctttttaggg gttttattta ttcaagagat cgtaccagaa actcgtggga
    18121 aatctttaga ggaaatcgaa caaagtgcat ctaaaaaaac ttatcctaaa cgtatttcta
    18181 tccatcattc ttaaagaggt tgtgacagaa gtggtcagct tcaagaaata agaaggaacc
    18241 gcttagtttc cagtcacaag gaacaatttc aaaaaacagc ttctcatgtt tgatgaatat
    18301 tgtgacttgt gaccagttgg taggagaaca ccgtttagtg gagaggtggt gaaagaaacg
    18361 ttcagccttg agcgatgaca aaagctctca caaacattgc gacgagtaac cgtaggagca
    18421 ataagaggcg gtaaaaaccc gtctcttatt tttcgttttc tttcactgtt tcccgttcaa
    18481 ctagtacagg ttcatagaga atatttggct gtgcctgtcc tttttcaatc gttgtgacga
    18541 tccaccgtgc ggcatcttgt cccaactttt cttttggatg cgtcaatgtt gtcaattttt
    18601 tattccctaa atggcttaaa gaagaatcgt ctgttcctac gatcgatagg tcatctggaa
    18661 tatgatagcc attttctgtc aacttatcta gcattaaact agctatttga tcgttatagc
    18721 aaatgatgcc atctaaagct tgttcttctt tcaaccgttg tactgttttt tcagcgattg
    18781 tttctcgtgt ttccgtggtg aaagtaatga tatcttccgt caaaaaacgc acattatact
    18841 gttcacacgc gctgataaaa cctttcatcc tgtattttcc ttgaagatcg tcgatttttg
    18901 tgatgaacaa cagacgctga tgtccttttt ttatcaaata ttctgctgcc ataaaaccga
    18961 ctttcacatc atctaaacaa atataagagg catttaactc ttcataagca gcattgatca
    19021 tcaccatcgg aatgccttgt tctctcaaag caacataaag tgctaagttt gggttatact
    19081 gattactttt cgtaggctca acgatcaaac catctacccc ataagcaatc attttcttca
    19141 aacactcttt ctccaattcg tgatcgttat tcgtactggc taaaagcaat gaatacccag
    19201 attctcgtaa ttcattttcg attcctcgga taatcgacgg aaaaatataa tcagagagat
    19261 atgtggtgat gacaccgatc gtttttgttc tgttcaatgg tgttttttct ttcttatagc
    19321 tgtcatctac atatgtgccc gacccttttt ctttacgcag atagccctca tttaccaaca
    19381 cagcgattgc ttgccgaatc gtatgtctgc tgacgtcata tatttcttgc agcttgaatt
    19441 ctgagggaat ggttgtattt acttcgtatt cctcacgaag gatcttttgt tttatctctt
    19501 ctgcaatatc ttgatatttt gccatttgcc ttgccccttt ttatttgtac gtacatatat
    19561 cataacgagt ctgcaaggtt tattcaagca aaaatcaagg tttcttgtgc tcataaggca
    19621 tacggaacag gttcaccaaa ttctggaaat ccttgctcat tccacgtaaa gcattgcgcg
    19681 ttcgcgtgcc gattaggatt gtctaacgga tccccttttt ggttcttctc tggtcgagca
    19741 tgatagatca aaatatcaaa gcacccgtct tctgaaaccg taaacgagtt gtgaccagga
    19801 ccaaattgct tatttttttc agaagaaacg aatactggct ccgataattt atgccatgat
    19861 tcttttaata aaagattctt gtgctcatca gcccacagca ggcccatggc atagttttca
    19921 tctgttgcac taccagaata cgtaatgaat attttcccat tgcgagtaag gactgctgga
    19981 ccttcattta ctgaaaaacc ccgtttttcc cattcatact caggtataga aaggaggatc
    20041 tgcttcccct ttaacgtcca aggattatcc atttcggata gataaagatt agaattccca
    20101 gtaatttcag gatcttgttg ggcccacaca taatatagct ttccttgaga agagaaagtt
    20161 gttccgtcta aactgaaagt ttcccttttc gtttttattt gtcccttttc tatccaatct
    20221 gtattcattg gatctatatg ctgattttca agtacgaaca tgcggtgatg atgagattca
    20281 tcacgtatag ttttatgatt gcttgcagca aagtaaatat accattttcc attgatataa
    20341 tggacttcag gtgcccagat caattcactc atcggtcctt cttcatgagc ctgccataca
    20401 atcaggcttg cagcatgttc taattcattc agtgactttg cccttcttaa ttcaatcact
    20461 tggtagcctg gaaccgatcc tgtaaaataa taataaccat ctgtatgttt atatacccaa
    20521 ggatctgccc gttgccgaac gataggatta ttataaagtg tcttcatcat aacaaatttc
    20581 ctcacatttt ctttattcta attacattcc aagagtattt ttctatccct acatttaatt
    20641 cgtcatgttt ttctattgaa aaatagttta tttcaggttt tattttttct ggttcttcac
    20701 gtgtattttt gtccaacaga tcgctactgg ttaatgtgta gtgctctcct tgatctagca
    20761 aattgaaatc atgttcaatc gttatctttt gttgttcatt tgtgcgattg atcaagaaaa
    20821 tagtcagctg attgccgtta tctacgatca cactgtccac ataaggaaca ttttttatct
    20881 tttcacaatc ataaacaggg caaatgattt gttgtttcaa tacttgacct ttagcatatt
    20941 tcgataagtg ttgcatcaca taataagttg gattcctcca tgcttgtcct ttagcatctg
    21001 tcagtattaa aggtattgtg tttactaaca atgattgaca actaatcttt acgcgatctg
    21061 cgtgtcgtaa aatagccagc cctaatgaac caaataataa tgtatcttcc atagtaaagt
    21121 aacaccaatc gatgggacta ccgacttcaa aatccctatg tcttttttcc ggttgggcat
    21181 gtacattcca ttcatcaaac gctagataca ttgttttctc acttctcaaa tatcctttta
    21241 cataatcaca agtagcaacg atttcttcaa tttgacgatc gaatcgataa gcttttgcaa
    21301 ggtatgtcgc tgtatcatca cgctcatttt taggaggttt agtcaagtct tcttcatcat
    21361 acttatcaat atagttatgc aaagctaaat aatctacatt ctcataagct tcttctaatg
    21421 cgatacgatc ccattcaggg tacgatggta aacgtggcgt agagcttcca actaagattg
    21481 tttcaattga atcatccact aacttcatga cttttgaggc ttcatttgct aacctaccat
    21541 attcataagc actcttagcc cccacttgcc atggaccgtc tagctcattc cctaaacacc
    21601 ataatttaac gccaaaaggc tttttttgcc cattttttat tcttaaatca ctccagaagg
    21661 ttccttttgg aaaattacaa tattctacta aattttttgc ttcatcaatt ccttttgttc
    21721 ctaaattcac cgtgaatatc ggtttcgctt gtacatgact gatccattta aaaaattcgt
    21781 ggagtccaaa agaatttggt tctatacctc gccatgctaa atcaattttt tttggtcgtt
    21841 gttctttcct acctacagta tccacccaat cataaccaga tgtaaagttt cctccaggat
    21901 agcgaatgac acctaattct aattccttta cataagagag gacatcttgt ctaaacccgt
    21961 caccatcagc tgtttcatgg cccggttcat aaatccctgt atagacgaca cttcccatat
    22021 gctcaacaaa tgagccaaac agccgagaac tgatctctcc taccgtaaaa tcctctctga
    22081 tttttacttt cacttcttcg tccaacagct ttccctacct ttcatttcct atagtcaaga
    22141 taatagatac aagtttccat acgccaccag caaagataaa aataaaagga gggaaaagaa
    22201 atatgagcag tacaaatcct aataacaata cgcaacaaag aatatttctc aaaaaatcaa
    22261 aaaatacttt ccatgcactt tgttcaaaaa tttgtaaaaa tgtgatatct ttgttttcag
    22321 aaatcacata tatccaggat aaaagaaaca tggaataaat aagtaaaact acatatccac
    22381 taattgaaag tacgattgtc tgttcttcta ataattgatt aacaagaaaa taaataatga
    22441 tcgttaacag actaaggaac aagttcttac caaaatgttg ctttattcct tgaaagaaaa
    22501 aataaatgat atttcctgat ccctcacctt tccattgcgc cattacataa aaaacagcac
    22561 atgtagcagg cacgatagta ataacaggca aacacacgat tacccagaga atacctaata
    22621 agatgtaatc agaaaccaca atcaactgtc cataaagttt agtctcaact attttcatct
    22681 tcctcactct ttcattccag acatagctgt tccttgaaca aaatatttct gtgcaaaaat
    22741 ataaaccact agtaatggca gcattgaaat aaccgttcca gccattacag gtccataaaa
    22801 agaaatgttc tgccctgtaa ataaagctaa ccctgctggt aaagttctca tttttgaact
    22861 acttgtcaat atcaatggat aaagcaagtc attccaacta ttcatcagcg tgaaaatccc
    22921 taatgataaa agagtaggtt tgctcaatgg caacatgatt ttcaaaaaaa tattaaactc
    22981 acttaatcca tcaatgcgtg ctgcctcttc caaagaatct ggtaaagtaa taaaaaagga
    23041 acgcatcatg aagataccaa atgcagttgt catacgagga atgatcaaac ctgcataagt
    23101 atcaagcatg ccaagcaaat tgacttcaat aaatagagga atcatgaaga cttggaatgg
    23161 gatcatcatt gtcagcaaaa cgaaatagaa caaaactgat tttcctttga aacgcatacg
    23221 agcaaatgca taccccgcaa gagaatcaaa gaatacagaa gtgatcactg tccctccagc
    23281 aaaaatcact gtatttttga tgtaatctaa taaagggatc gttgtccaaa ccttaatata
    23341 gttatctagg gtatagctat ctgcaaatat tctaggcgga aatgagataa tgtctttttc
    23401 gtgtttaaaa gaagaaataa tcagccacaa aaaaggaaac gcaataacca acaatataac
    23461 tagcatacta atcgttcgaa tgattttttt accactaact gcttttcgac tattcacagt
    23521 aactgtaatc gagctttctg gtgccataca ggtttccctc ctatttcatt tgtttttctt
    23581 tccgtgacat gtacacatta gtggagatag ctatagttgc aacaatgata aacaaaaccg
    23641 aagacagtgc tgatgcatag cccaattcat aaggtgctgt aaatcctcga ctgtaaatat
    23701 attgaacagc tgtttctgtc ttaaattgtg ggccaccagc ggttgcaaca tatacttggt
    23761 caaacacttg catcgaacca atcagattcg ttaaaataca aaaacctaag gagggaacga
    23821 tctgaggtag cgtaatgtta aaaaactgct gtcgatttgt tgcaccatcc atttgagcag
    23881 attcatacaa agagggagag attccctgaa tagcagtcaa gagaatcgtc atagtaacac
    23941 caaaattctt ccaaacagtc atgatggcta ccgtcggcat agcaagggtt ggatcgcgaa
    24001 aaaattgagg gatcggcaag ccgacttgtg aaaacaagta aggaatcgcc cctacattcg
    24061 gatcaagcaa catagaaaaa ataatcgcaa ttgacgtcaa tgaacaaata actggaatgt
    24121 aaaatgtcga acgacaaaaa cgattgaatc tggtattttt agataatgct actgctgcta
    24181 ataaaccaac gataatttgt gttggcgttt cgagtacggt gaaatataaa gaatgaatca
    24241 acgaattaac tgctcgttca tcactaaata tacgtgtgaa attttcaaaa cttacaaaat
    24301 ttcttgatgt aaagaaaata ttcaaatctg taaaactaat agcaaatgtt cctaaaagcg
    24361 gtatgacagt aaataataat aaaactaaaa aagatggagt taaaaacaaa tacgcagcac
    24421 gatcaggacg attccaatat ttggtgaatc cgttcatata gtccacctca tctttcattt
    24481 tgataaaata tacaatcttg gtttaaacga atctgaataa gatatccgaa caatcgctgt
    24541 gatttttgca ataacaccta tctgcaaata ctaggtcgat cattcagata tctgtatctt
    24601 gccaacagtc tatcctgtat aaagttctgt actatttttg cagtaattga ttgatggcat
    24661 catctgcatc gttcatgagt gtctcaggat cttctcctgc taataatttt tcaatcagtg
    24721 gattgatgat atcgttattg atcgcagaga tttgggtaaa acctggtaaa tatggctctg
    24781 catagtccat ttgtttcgat aattcagata caataggatc attttttact tcttcatctt
    24841 ttgctactga atccaagtag gcaggaaaac cattttcgat actccatttt ttaccaattt
    24901 cagttgtatt ccaatatttc aaaaactcat agacagcttc ttttttatta ttatctgtac
    24961 ttgccggaat ggcatatcct acgccatcta aaatagctgt ttttttgtct gaatcactcc
    25021 cttgtggtaa ggtagtcaca ttataatcaa tctcgtttgc tttcaatccg ttatttaacc
    25081 atggcccatt gatttcaatg gctagttgac cagcattcat taaattgtcc atttcggcgc
    25141 cagaaatcga ttctggacca gtcttgtcta catggatcat tttttggatc gcttttaacg
    25201 ttttaaggtt ctcaggagac gcaaattcag acttagtata atcatcgttc actaatttac
    25261 cgccatttgc taacatccag ttatataacg gtgcagttcc atccttattg aagacaaaac
    25321 ctgatacatt tttactacta tcagttaatt ttggtgccat ttctgtcaat tcttcccaag
    25381 tagtaggtgg ttgttcagta tctaatccag cttgtttaaa caaatcatta ttccaataca
    25441 tatacatgcc ttgtacctgc atggggacaa aatactgttt accttctact tcacctaatt
    25501 caatagccgt ttctttaaaa tcagatttat ctactccatc atattcccag aaatcgtcta
    25561 atggttgtac cgctccgttt tctacatact gtgcaaaatc tggataattt aatgcaataa
    25621 agtcaggtgc ttttttagaa gaaatcgctg taggaagttt ttcattcaaa ttggcccaag
    25681 tcatgatatc catttcaatt ttgatgtttt tatcatttgt tttattaaat tcattaacga
    25741 tttcttgcaa tatttcacca tcagatgcag taaacccatt ccaaaaagtc aaagtcactt
    25801 ctttatcaga atcagattct gctgaacttc cgccaccgca agctcctaaa atacctgttg
    25861 cagctaccaa caaagagcca attaaccatt ttttaccttt cattttttgt tcctccttca
    25921 tctgataaac gacatctgac cacattccaa gatagcggtt tcaataaaca attgattttc
    25981 ccatcttcag cttttacatt tgttgaatga cttggtttta cttgttcact tttaggaaga
    26041 ttagttgctt ttgtatcaaa tccactcatt tcagaaaaat caatcactcc ctctaatgat
    26101 aattcagaca agtgaacagt tagattcatt tcttcttctc cacggttaac tgcaaatatg
    26161 acaagttctt tgtcatttat tacggctata ctttctaaat acggcacttc ttcaaaatct
    26221 tccgtcgcat agtttgctga acgaatttgt gggcttaaca cctctccttg tccatacaca
    26281 gcagcttgca taaatggata atagatcgtc tgtctccaag cttctccgtt tgtttctgtc
    26341 ctgattggtg caataacatt taccaattga gcaagacaag caatctttac tctatctgca
    26401 tgtttcaata aagtgattaa tagacagcct aatagtaatg catcttcaaa attatagtta
    26461 tcttctagta aaggaggagc aatctgccaa ggcgctgctt gctcatcttg ttccgctgaa
    26521 tgataccaaa tattccattc atcaaaggac aggttgatct gcttcttact atgtttcttc
    26581 gccttgactg tatcgcacat cgctgtcact tcagaaatga accgatccat gtctaaggaa
    26641 cgtgcaagat aatgagaaag atcatttttt tggttgccat aatattgatg cagagacaaa
    26701 taatctattt gatcgtacgc ttgatcaaga actgttaact cccaatcacc aaatgtaggc
    26761 atttgccgat tcgaacttcc gcataaaacc acctcaattg aatcatctac gagtttcatc
    26821 gccttagccg tttcctctgc taaccgtcca tattcttccg ctgttttatg tccaatctgc
    26881 caaggaccgt ccatttcatt ccctaaacac catgtcttaa ttccaaaagg gctctcttga
    26941 ccattcgaac gccttaaatc actccaataa gttcctttag gaaaattaca atattcgact
    27001 aaattacgag ctgcatctac tccacgagta cccagattga cagccatatt gatttcggcc
    27061 cccacatgct gacaccagtt ataaaattca tgaatcccaa cttcattcgt ttcaattgtc
    27121 cgccaagcta aatccaacct tctaggtcta tttgctatgg gcccaatact gtcttcccaa
    27181 cgaaatcctg acacaaaatt tccaccagga tatctaatca tgggaatgtt caattctttt
    27241 accaagtgaa tgacgtcttg gcgaaatcca cttttattag ctgatggatg atctggctga
    27301 taaatccctt catatactgc tcgtcccata tgttcaataa atgaactgta caaccgcgga
    27361 tcaactttgc ctacacgctt gacactacta atcaacattg tggcttccat aactgacctc
    27421 ctttaattta tacatgaata atacacctcg ttgaaagcgt tgtcaataat ataaatgtta
    27481 aacttactta ttttttatcg attttaatta accaaaatat taataatgat taaaacaaat
    27541 aatttaatat aacttttatt aacaaatatg ttaatatata agaaaaacct tttaagaggt
    27601 gatatatatg caactacaaa taaacgaaga atccttaccg gtatatgaag cattagctag
    27661 taaaacaagg atcaagatca tccagctact ttccaaaaaa aagatgaatg tcaaagattt
    27721 ggcaaaagaa cttggagtga gcagtgctat cacgacgatg cacgtgaaaa agctagagga
    27781 agcaaacatc atcaaaacag aaaaagtagg acaacaaaaa atttcgagcc ttcgtgtcga
    27841 taaaatcgat atcagttttc cagaaaaaat attcaatgct tttgatacga aagaaacatc
    27901 gatacctatt ggtcactata caaattatgc aattgaacca acatgcggtt tagctacgat
    27961 ccatgatttt atcgggaaag tggatgaacc acgctatttt atggatcctc gaaggatgga
    28021 tgcccgcatt ctctggttta ccagcggatt tgtcgagtat caggcaccta attttttaaa
    28081 tacagaggat acattggaga tgttggaagt ttctgtggaa atttcttctg aatttccttt
    28141 ttcaaatgac aattggcctt cagatatcac tttcagccta aatggtgtgg agctaggaac
    28201 atggacgagc cctggagatt ttgctgatat ccgcggtaaa tatacgcctg attggtatcc
    28261 agataatctt aatcaatacg gcttgctgaa gacgatccga attaccaaac acttgacgaa
    28321 tatgaatgga gaacccttgt caaacatcac gatcaacgac atccctaaag agcaagacac
    28381 ttggcatttg cgaatcgaag tgaaagacga tgccaaacat gtggggggct gtactttatt
    28441 tggtaaagga ttcggtaatt acgatcagga tatcaaatta aaagtttact acagctgata
    28501 tttttctttt ctattttata aaacaaaaac agccaatccc tatgaaggga cggctgtttt
    28561 tgctttattg ttatttccag aaatcatcca aaacggaaat tggcaaatgt cgtttatgtt
    28621 gtgtcttgtt ccaccatgct tcgatttttt cttgtgcttg agcgggaact tcttttcctt
    28681 ctagataatc atcaatttca ttatatgtga cacctagtgc gacttcatct gcaatcattg
    28741 gtttcccatc ttcaagatct gcagtcggaa tttttgtgta taatttttcc ggtgcattca
    28801 atgcttgaag caattgtttc ccttgtcgtt tgtccaaacg gaataatggc aaaatgtcgg
    28861 ctccaccatc accaaatttc gtgaagaatc cagtaatgtt ttctgcagca tgatctgtcc
    28921 ctaatacggc tcctgctctt tctccagcta cggcatattg cgtaatcata cgttgacgtg
    28981 ctttgatatt tcctttgtta aaatcgctga ttcccacacc tgcttcgctt aatacttgta
    29041 cttgtgcatc aacagctggt ttgatattta ctcgcagact aacatcgggc tggataaagt
    29101 caagagcagc ttttgcatct tcttcatctg cttgttcacc ataaggaaga cgaacagcga
    29161 taaattgata gttttcatct tttgtttctt cacgcatttc ttccatcgtt agttgcgcca
    29221 aacggcctgc taaagtagaa tcttggccgc cgctgatacc tagtacaaaa gttttaagaa
    29281 acggatattt tttcaaatat gctttcataa agtcaatact tttacgtatt tcttcttttg
    29341 gatcaattgt tggtttgaca cctaattcat tgataatttc tgtctgcagg ctcatttatt
    29401 ctcctcctat gcttctgtat gaagttctgc tacgcttttt ttcattcgtt ccatgatagc
    29461 cattttatgg ttccagcatt cagtagacag atcgactggg tatttttgcg gattcaagtc
    29521 tcgtttatac tcttcccata gtgaatctag attttctttt gtatattctt tgatttcgtt
    29581 tagtgcaggt aattcgtaaa ctctttttcc ttcgataaag atatcttgta aaactgggcg
    29641 agctgtaaag tctcgaacag ttttattgat aaacgtatgc actggatgga acatgaagat
    29701 agcttcttct tctcgagggt cttcatccca taatgtcacg tagtctcctt cagatttccc
    29761 atcaaaattt cgagtgatgc gccacacttg ttttttccct ggagtagtta ctttttctgc
    29821 attgcttgat aacttgatcg tatccatcat ttttccttca tcatcttcga tcgatactag
    29881 cttgaatact gcaccaaggg ctggctgatc ataggctgtg atcaattttg tcccaacacc
    29941 ccatacatca attttagctt tttgcatctt taaattcaaa atcgttgctt catccaagtc
    30001 attcgaagca tagatttttg cttccgtaaa tccggctgca tctaattgtt cccgaacacg
    30061 cttagatata taggccatat ctccactgtc gatgcgtacg ccttggaagt tgattttgtc
    30121 acctaattct ttcgccacgc gaatcgcact tggcacacct gatttcaacg tatcataagt
    30181 gtcgactaag aacacgcagt ctttatgggt tttagcgtag gccataaatg cttcataatc
    30241 atttccataa gattggacta acgaatgagc atgggtcccg ctagctggta tcccaaatat
    30301 cttcccagca cgtacattgc ttgttgcatc tgctccgccg atatatgccg ctctagttcc
    30361 ccagactgct gcatccagtt cttgtgcccg tctagttcca aattccaata gtggatcttc
    30421 tccgatgaca gatttgatac gagctgcttt tgtcgcgatc aacgtttgga aattgaccat
    30481 attcaacagt gctgtttcta ctaattggca gtgcgctaaa ggcccttcca cttggattaa
    30541 tggttcattt gcaaaaacta gttctccttc acgagcagaa cgaactgttg ctttaaattc
    30601 aaaattttgt aaatactcca aaaaaccttc aggatagact tctaatccac gcaagtaagc
    30661 aatatcggaa tcattgaacg tcagattctc taaataattg actaaccgtt ccaatcctgc
    30721 aaaaaccgcg tatccgtggt taaaaggcat ttctcgaaag taacattcaa aaacagcatg
    30781 taaatcagct cgacctaatt cccagtatgt ctgcatcata ttgatttgat atagatccgt
    30841 atgcagcgtc aaactgtcgt ctgggtaagt attattcatc ttgtattact cctcttggca
    30901 agttttcatt tcctacccat tataacaaaa aaaattaata ggaaaagaaa tcttccattt
    30961 tttctgaaaa agcacatgtt ttacggatat ttcttgctaa aaatgaactc catctgctaa
    31021 aactatcctt tcttattggt atttaaccta aacgagaaag aatacttatt ttattcaatg
    31081 tatccgagac acgaagaaat tagcgttttc tatttttctt acttgataaa ataagtagat
    31141 tttcctacta caatcgtagc cgttaagata ccgatgattg aacaaatata accaaatgtc
    31201 tctacaacat aatcaatggc aaaagttttt gaagcaataa tacgtctttc cttttttgct
    31261 tcttatcccc aaagaaacgg atataactta ttatgtattg aatttttttg gaaaggcgaa
    31321 ttatgacaag atataccttg cgttgaaaaa actcgcggaa aaaatatcac acgtttttaa
    31381 aaagatacaa agtaagaaag cagctgtcaa tagaatggaa acaaaaatgg cgagacatca
    31441 atcagtctcg ccttgttttt tattgtatac attagatatg gagcaggtta ccataaagat
    31501 gattattagt cgttattaaa tagaatcctt cgtatttttt tgttctatca ctacaatatc
    31561 tttatttgga cgtttgaatt gtattccggc acgttctagc tcctgtttca ctcctacatg
    31621 gactttgaca tcttctcgtg tcatttttaa aacgtgatga atcgcatagt cgatttcttg
    31681 ccttgtgatt tttttcttcg tattgatcat cacgacttgc tttttatcat atgtgtctac
    31741 caatagcagt tgtgttcgat ctaacgaaaa taatttgtaa taattaatag ccgtattccc
    31801 aaaaaagaat tccactactt taggataaaa tgtcttaata tttaaattac tattcacagg
    31861 tgtttcgatt agcttcatct cattcctctt ttctatatag tcgatttaga tccaatctta
    31921 agttatgtta ccatctttcc tagcattaag gaatcggtta caattgaacc tttaaagaca
    31981 aaaggattta ccttttatca cttaatagta taacataatt tcgtgagaaa aaaatacaat
    32041 tttttcttga ccatctcgtt acgtaaagga ttatgcttac atttgtcagg aggaaaaata
    32101 atggagtaca caataaagaa aatgtcagag atatcaggag tcagtccgag aaccttgcgc
    32161 ttttatgatg agattggact gctaaaacca gctaggatca attcttcagg ttatcggatt
    32221 tatggcaaaa aagaagtcga tcgtctgcaa cacatcttat tttatcgaac aatggcattc
    32281 aagttggatg atatccaaga ggtcttagac aatccatctt ttgaccacca gaaagcttta
    32341 atcaagcatc agcaaatgtt gctggaaaaa cgggcacaaa tcgataccct cttgacaact
    32401 gtccaacaga cacttgatat gtacgaagga ggaagaaaaa tgagtgacaa agaaaaattt
    32461 gaagggttta aacaacaaaa gttgaaagaa aatgaagaat cctatggaca agagattcga
    32521 caaaaatacg gaaaaaaaaa ggttacagca tccaatgaaa aatggatgaa tatggataaa
    32581 gaaacgtatg aagaaatgca aactgttgaa aagcagatgt tatttgatct cactctttac
    32641 ttaaaagaac cagaagatga aagcttagca gaccgtatct tccaagctca taagaagtgg
    32701 ttctcttaca gctggcctga atatcagcca aaagcgcata aaggactagg aatgatgtac
    32761 gaagccgatg aacggttcac tgcatattat gacgagcgaa gtggtcatgg tgcagcaaaa
    32821 gctttaaatg aaattatcca aaaaaaggcg taatctttta catgatccaa caaaaaagta
    32881 cacgtaaaat gacctaataa caaaacagca gacacccaag ttagattttt atgctaactt
    32941 ttggtgtctg ctccattctt tcacaagttt tttcatccta ctttaaatat attcatcgtt
    33001 gaataaacgt ataaggtatt ttcactttat cctttttttc tgtaagaaac aattgaaatg
    33061 ccatttctcc gcaagcttcc agatggtggt cgatggttgg gaaaccaaga agctcgctga
    33121 tcagcaaatt atcgcgtcca atcaccactg gtgtcttatc ttgcagatag ctttgcaaga
    33181 tgcctgctgc aaccatatcc gaatttgtaa agacaccatc aactccaagc tctttaaaaa
    33241 agaagcctgc ttgttttcct ttctctgcat ctatacaatc ccaaaaaaca agtgattcat
    33301 caaaagatgg aaaaagttga tgacatagct gcaaagtgat ttttgagtta taacttagcc
    33361 tgccacttcg ccccaacgtg atgcccaatt gctttatacc ttgctgcttc aaataagtaa
    33421 gaccttctgt aattgattgt tctcgatcaa taaagacaca gcttgcctgt tttcccttga
    33481 tttcttcaca aaaaactaga ggtccatatt tttgatatgc caataaatca tctagtgtat
    33541 tggcacgaga cgtaatgatc aatccatcga aagctttagc tgcaaattct tcaagatacc
    33601 ttcgctcttt ttctttatga tagcccgtcg gtaaaagtgt cactttgtaa tcataatcaa
    33661 acgctgcttc aatgatccca ctgatcaact gatcaaaata cggatgattg gtataaggca
    33721 gaatcactcc aatgcttttc gtttttccat aacttaactg tctggcattt gcattaggga
    33781 tataatcgac ttctttcatg accgcaagta tttctttcct tttttcctca tctacatatg
    33841 gatgtccatt gattacacgt gaaatagtag aaactgaata acctgtgagc tttgcgatat
    33901 ctcgaatgtt tgccactgct gcttcgccac ctatacaaaa agattttctt gtaaatagtc
    33961 taccacagct ggaccgcatt caaaaaactg atacattttt ccttcatgcg aaaaactgat
    34021 ccgctgcccg ccccaatata tatcttttgt caaattttcg atttcattca ttggtatttc
    34081 ttttactata ttcctattca acccttgaaa actgtacaac gttaatacgg atcccttgaa
    34141 ctcgacaaac gcataaaaat aattgttcgt tgtgccatct gttatctcta cataagtatt
    34201 cattgcaagc cctccttttg atactttgag tatagtgtat gaaacgcgtc tcatagcaag
    34261 gagtttgttt tgccaaagaa aagttttatt cctctttcat tattaccaaa gtctcttatt
    34321 ttaaattgaa tacattataa tgatactgta aatatatctt tattattagt gaat
//
LOCUS       DAJSMK010000023        31779 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.023, whole genome shotgun sequence.
ACCESSION   DAJSMK010000023 DAJSMK010000000
VERSION     DAJSMK010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31779)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31779)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31779
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.023"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            683..1552
                     /locus_tag="ON488_001092"
     CDS             683..1552
                     /locus_tag="ON488_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HCR3231300.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1761..2786
                     /locus_tag="ON488_001093"
     CDS             1761..2786
                     /locus_tag="ON488_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCR3231301.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2825..3775
                     /gene="manA"
                     /locus_tag="ON488_001094"
     CDS             2825..3775
                     /gene="manA"
                     /locus_tag="ON488_001094"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HCR3231302.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3869..5572
                     /locus_tag="ON488_001095"
     CDS             3869..5572
                     /locus_tag="ON488_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3231303.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5574..7607
                     /locus_tag="ON488_001096"
     CDS             5574..7607
                     /locus_tag="ON488_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCR3231304.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7618..8058
                     /locus_tag="ON488_001097"
     CDS             7618..8058
                     /locus_tag="ON488_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR3231305.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(8258..9385)
                     /locus_tag="ON488_001098"
     CDS             complement(8258..9385)
                     /locus_tag="ON488_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231306.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(9388..10065)
                     /locus_tag="ON488_001099"
     CDS             complement(9388..10065)
                     /locus_tag="ON488_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231307.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            10329..12095
                     /locus_tag="ON488_001100"
     CDS             10329..12095
                     /locus_tag="ON488_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HCR3231308.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            12110..12547
                     /locus_tag="ON488_001101"
     CDS             12110..12547
                     /locus_tag="ON488_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR3231309.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12560..13711
                     /locus_tag="ON488_001102"
     CDS             12560..13711
                     /locus_tag="ON488_001102"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HCR3231310.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13773..14471)
                     /locus_tag="ON488_001103"
     CDS             complement(13773..14471)
                     /locus_tag="ON488_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HCR3231311.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(14464..15816)
                     /locus_tag="ON488_001104"
     CDS             complement(14464..15816)
                     /locus_tag="ON488_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HCR3231312.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(16039..17443)
                     /locus_tag="ON488_001105"
                     /pseudo
     CDS             complement(16039..17443)
                     /locus_tag="ON488_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
     gene            17604..18341
                     /locus_tag="ON488_001106"
     CDS             17604..18341
                     /locus_tag="ON488_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HCR3231313.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            18466..18945
                     /locus_tag="ON488_001107"
     CDS             18466..18945
                     /locus_tag="ON488_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HCR3231314.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18942..19709
                     /locus_tag="ON488_001108"
     CDS             18942..19709
                     /locus_tag="ON488_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231315.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19939..20508
                     /gene="lepB"
                     /locus_tag="ON488_001109"
     CDS             19939..20508
                     /gene="lepB"
                     /locus_tag="ON488_001109"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCR3231316.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20612..21214)
                     /locus_tag="ON488_001110"
     CDS             complement(20612..21214)
                     /locus_tag="ON488_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCR3231317.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            21320..21789
                     /locus_tag="ON488_001111"
                     /pseudo
     CDS             21320..21789
                     /locus_tag="ON488_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21895..22479
                     /locus_tag="ON488_001112"
     CDS             21895..22479
                     /locus_tag="ON488_001112"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HCR3231318.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            22482..23555
                     /gene="prfA"
                     /locus_tag="ON488_001113"
     CDS             22482..23555
                     /gene="prfA"
                     /locus_tag="ON488_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HCR3231319.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23548..24387
                     /gene="prmC"
                     /locus_tag="ON488_001114"
     CDS             23548..24387
                     /gene="prmC"
                     /locus_tag="ON488_001114"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HCR3231320.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            24380..24559
                     /locus_tag="ON488_001115"
     CDS             24380..24559
                     /locus_tag="ON488_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231321.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24581..25606
                     /locus_tag="ON488_001116"
     CDS             24581..25606
                     /locus_tag="ON488_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HCR3231322.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25781..27025
                     /locus_tag="ON488_001117"
     CDS             25781..27025
                     /locus_tag="ON488_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HCR3231323.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            27178..28125
                     /locus_tag="ON488_001118"
     CDS             27178..28125
                     /locus_tag="ON488_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3231324.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            28259..28888
                     /gene="upp"
                     /locus_tag="ON488_001119"
     CDS             28259..28888
                     /gene="upp"
                     /locus_tag="ON488_001119"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HCR3231325.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(29027..29269)
                     /locus_tag="ON488_001120"
     CDS             complement(29027..29269)
                     /locus_tag="ON488_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231326.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            29390..29462
                     /locus_tag="ON488_001121"
     tRNA            29390..29462
                     /locus_tag="ON488_001121"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:29423..29425,aa:Thr,seq:cgt)
     gene            complement(29581..30219)
                     /locus_tag="ON488_001122"
     CDS             complement(29581..30219)
                     /locus_tag="ON488_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCR3231327.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(30342..30974)
                     /locus_tag="ON488_001123"
     CDS             complement(30342..30974)
                     /locus_tag="ON488_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCR3231328.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            31325..31624
                     /locus_tag="ON488_001124"
     CDS             31325..31624
                     /locus_tag="ON488_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCR3231329.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        10816 a         5574 c         6383 g         9006 t
ORIGIN      
        1 tttttagggg ctgtgacaaa agtcgtgtca cagtcccttt ttccgaataa acggtgttca
       61 atcagctgtc cttcggtatt agctcaaaaa acggcaaaat atgagaagct atttttccgt
      121 tttgtatctc taatactcag gtcaaaccgc tgattttaca acctcttcct taaacggtgt
      181 tctcctgcca actcctcggt cacaagtcac aatagtcaac aaacctgaga agctgttttt
      241 tgaaattgct ccttgtgact cggagttaaa cggcaggctc acaacctctt ggtaaacggt
      301 gttcaaaagc cagtttctcg gtattaagcc aaatttatgc aaaaatgtag aaagccattt
      361 tcacaaaatt tttcttacta ctcgaaacta agcgactttt tcacaacctc ttccttaaac
      421 ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat aggaggagct
      481 atttttgttt ggctgttctt attacttgat gcagaacagc tttttcacaa cctcttttta
      541 taagagtttt tactcattaa tttacaaaaa acaagcaaaa tgcgaatttt ctcacatttt
      601 ttttaacaaa atcaaagtta ttgcttgaaa gaagaagaat ccatcgttaa aataaagctt
      661 gacgtagagg ggagcaagaa atatgaaaga ttttcaattg ggggctgcca cctatttaaa
      721 aagtgtagcc attcgggtga aagaccgaga taaaatgatt gatttttaca agaacgttgt
      781 tggctttgat ttgaaaagag aagaaaacga attagccatt ttaggaacag aagaagctgg
      841 aagtgaaatg ttgctgctgg aagaaagtcc tagagcgaat gatcacatgg gggtgatcaa
      901 aaagctgaac cgtttttcat tgattatccc tagcacagaa gaaatggcag atatcctttg
      961 tcgtatccgt aaaatgaatt atccaatcaa agaagcttta gaagatcatg gacgtatggg
     1021 gattttgctc gtagacccag aagagaatga attggaaatt taccatgaag agaataagaa
     1081 cgaccaaaga gaaattccag aaacaatgga tcaagaagca ttattaagaa aatctgaaga
     1141 aaaattcagt aaactatcaa caggttctta ttttgaaaaa atccatttaa atgttactaa
     1201 cttaacaaaa gaacgccaat ttcttaatca tgtacttggt ttgaaggtac ataatgaaga
     1261 agagggcatc catgtattga atgaaggaga tttccatgtt ggtttgacag aagctagcgg
     1321 aggcgcaatt gatttgccta cagatgaagt gattggactt gattttctga aattcatgat
     1381 cgatactgaa agcatggaag gactgattgc tcacttgcag caactatcag ttgatttctt
     1441 cttagacaaa aagcacacag tactcacaat ctatgatgct ataggaatcg aatggtggtt
     1501 cgtcagtgag ccaaaagaaa agaataaaac tgacattcga tgcgacgctt aactttttct
     1561 ttcttaacga ttgtcgcatg tctcgtcatt ttatgaacgg tcatactatc gcttattcta
     1621 gagatagaaa gagaaaatag tataccgggg gaaactgcgc ggtttttcgc gcagtttttt
     1681 tgtgtaaaaa aggttgattc ctcatagatt aagctttaag cttggactgt aagaatctga
     1741 tagaaaagca ggagaaaaag atgtatccac acacgaaaca gcttattttg aaaaagatgg
     1801 aagaaggatt ttatccaggt gtagcagtcg ccttcataaa agaaaatcaa gtagaaacat
     1861 ttacagccgg ctttgcccaa gtcgttcctg aaaagcagct gatgacagaa gatctgttgt
     1921 ttgatgcagc ctcactgacg aaagtcgttg caaccacttc attagtttta cgtctattag
     1981 aagatggaaa gatagaactc gatcaaccgc ttcataaata tcttcctgaa tttgaaaatc
     2041 agacaatcac tttgcgtcat ttactgacac atacttctga tatcaaaaca tggataccaa
     2101 acagagataa gctatctcag gaagaattga tcgccgctta tttgaagcta gaaccaggtg
     2161 agcaactagg aaaagaagta aaatatacag atgccggtac gattcttctt gggttgatgc
     2221 tagaggaaat ttaccaagaa actgcagtgg aaatctttca agaacaagta ttggaaccat
     2281 taggaatgat gaacagctta tttcttcctt ttccttccaa aaaaatcgtt cccacagaac
     2341 aactgccttc gggtgaggtt ttgcgtggac aaactcatga tccgaaagca agagttttgg
     2401 ctgaacatgc aggtaacgcg ggtctcttta ttgatttgaa agacagcatt acttttgtcc
     2461 aaatgtattt gaacaaggga aaaatccgta atggtcgttt tttagaagaa gagacgattg
     2521 attctttact gcaagatcaa acaccgaaaa aaaatggcta tcgttcttta ggatgggact
     2581 taaaaaagga tgtagaagac ggtcatgcga ttctttttca tactggttat acaggtacgt
     2641 ttttcttgat tgatataaaa acacaagaag cgttgatatt tttgtcaaat cgcgtacatc
     2701 ctgtcgatca tcgtgcggag tatctcatat gtcgagatga aattgttgaa aactttttga
     2761 aagagaaagc ggtattaccg aaataatgct ataatagcta tgaaaaatga gaggagtttg
     2821 aattatgcag gaacctatgt ttttaaaacc agtttttcaa gaaaaaattt ggggaggaag
     2881 tcgtttacgt tcagtctttg gttttgatat ccctaacgat aaaatcggag aagattgggc
     2941 gatcagtgcg catcctcatg gtgtcagtgt agtagaaaat ggcgaattca aagggaaaag
     3001 attagatgaa ctatggtcag aacacaagga attgtttggc catccttcag aaccagtgtt
     3061 tccattattg atcaagatct tagacgcaga agatgatcta tctgtacaag tacatccaga
     3121 tgatgcctat gggatgaaac atgaaggtga attaggaaaa actgaatgct ggtatatcat
     3181 cgatgctgaa cctggtgcag aaatcatcta tggtcatcat gcaaagacaa gagaagaact
     3241 agctgagatg atcaaagatg ggcgctggga tgaccttttg aagaaagtac cagttaaaaa
     3301 aggtgatttc ttttatgtac caagcggaac gatccatgct attggtaaag gaatcatgat
     3361 tttagaaaca cagcaaagtt ctgacacgac ttaccgcgtg tatgactacg acagaaaaga
     3421 tgcgcaagga caaacaagag agctgcatat ccaacaatcg atcgatgtaa caactgtccc
     3481 tgcgaaaaca ccagaattac aaatcaaaga agtccgaaaa gggaattcat cgatcgtcac
     3541 ttatttagaa actgagtttt tcaatgtata tgagtgggat attaaaggaa tcacatcttt
     3601 caaaaaacaa gccccttata cattgatgac ggtaatcgaa ggagcaggag accttgtcgt
     3661 tgacggaaaa acatatccat tagaaaaagg aacaagctgt attattccaa atggcgtttc
     3721 tgagtgggcg gtccaaggtg aactagcaat cattgcgtct gaaccaggca aatagttccc
     3781 agatagctga aagcagcaga cggtttttcg tttgctgctt tttctacata aaatccgtcc
     3841 atcaataaat agaagtctgg tgaaaaagat ggaatacaaa tggaaagcaa acaacagcag
     3901 tcgcgtgtct atgaaacaac tgagaaaagc tggacatcac ttaaatgaaa tgatcatgcc
     3961 aaatctaagt ctgtttatcg cttggggaat cttgtcatta gcaacaaaag gtgtgtctgg
     4021 cgatttgcac accacattag aagaggtatg ccattggatg atccagctgc ttttacccat
     4081 cttgatcagt tattcaggcg ggaaatcggt agggggacaa aaaggggcag tcgccggtgc
     4141 aattgcttct ttagggttga tcgctcgttc caatgctcca caaatcgtag gagcgatgat
     4201 tatcgggccg cttgccggca tcgtatatga acaatttgtt tctagattcc atgtgaaatt
     4261 caaggctgga tatgaaatgc ttgtcagcaa cctactagta ggactgactg gtagcgttat
     4321 ttgtataatt ggaatcgttt ttattgaacc agttttaaat agtgttcact tgttgctcgc
     4381 ctccgttgtg tcttggctag tcacaatgaa tctgttacca cttgtcagtc tgatcttaga
     4441 acctctaaaa gtactatttt tcaataatgc aatcaatcat ggtgtattga cacctttagg
     4501 aatcgaattc tcacaaacag tcgggtactc ttccttattt ttgatggagg caaatcctgg
     4561 acctggttta gggatcttac tttctatcct ttgttttgca gaaaaacagg aaaaagtaaa
     4621 tgcgagtgga gcattgatga tccatgcgat tggcgggatt cacgaaatct attttccatt
     4681 tgtcttgctg cgaccgtatc tatttttagc tgtaatggct ggtggggcaa gcggcacgtt
     4741 gatatttcaa tggttagata cgggattagc tgcacctgta tcgcctgggt cactactcgt
     4801 gatttttgcc aatgcgcctt atccacaact agctggggta agtataggga tagcaatcag
     4861 tacatttgtg accttcattt gtgcagcgat actattgaaa ttaccaaata aagaaaaaga
     4921 gaacaaaacg gtcaaagaaa ggggagaaat cttggaacca tctatcattc attccgtcat
     4981 ttttgcttgc gactcaggta tgggatcaag tgctatggga gccgccctgc tgaaaaagaa
     5041 attagcagca gaaaaaatcg atctttctgt cggatacagc tctatctatg aattgaataa
     5101 ccaagtaaat cagctggtta tcgtgcaaca tgaactagcg ggtcttgcaa gagaaaaagt
     5161 acctcaaagt caaatctatg tactggatca ctttttggaa acagatatct tgctgtcacg
     5221 aataaaagaa gcgatccaat ttccaaagcg ggaagaaaaa aaagagatag cagatatcac
     5281 agaacaaaaa acgtcgcctg ctaatattgt atttttgtat aaaaacaaca gacgcggctc
     5341 acaaactatg ggcatgacga ttttaagtca attagcaaaa aaagcgaaaa aacagtttgt
     5401 tatctcaaaa gaatcaatag aaaaaatcaa aatccaagaa gaaacgattt atatcgcaca
     5461 aagagaacta gctgtaactg aacagctaga agaaaagatc cctcggctag ttctagttga
     5521 acattgggta gctacgaatg aatacgaaaa actcgtgaag ggagaaatat aagatgtatt
     5581 tatcgcccag agaaaaacaa ttattagcag aatttctcag tagcccgtca cctgtatcta
     5641 tccaaaaaat gatgaattta ttgaaggtca gtaaacggac tatttaccgc gaattagata
     5701 atcttgaagt ctcattgaaa tcggtaaatg cttctttgaa aaaagcagct agaggctcat
     5761 ttgtcattga ggcatcagaa gaagtattag agcaattaaa agaaaataca gatgggaaaa
     5821 gtaatgactt atccactgct aaacgacaac acgcgatttt agccgagttg ttactgacga
     5881 cagagccgtt gagtcttgct catttcatgg aatcatatcg catcagtaat accacttttt
     5941 atgcagatat caaacagttg gaagaaagta ttcgccaact gcctttggaa atcattcgga
     6001 accagggata cgagatcgaa ggaccggaaa aataccgccg gcttctgaca gcgaatgtat
     6061 tagaattaga aatcaatgaa tatgaacttt ttcatagtat ttctttcgat gcatcactga
     6121 attatttttt tcgattcgtt gatccgcaac atctatctct tgcacgcaaa gtaatcgggg
     6181 aagaattgat ccaaaaaaag accaatctaa gtgatagaaa gcttgaacat ttggttttga
     6241 tgctgacatt gacgatggag cgtgtgacga aaaatcattt actgacaaat gagacatata
     6301 atagtctggc aaacaaagaa ttactacaga cagctaaacg attgttttca cggatcgctt
     6361 ctgagacaaa acaactttat ccagtaaatg agatcgtctt ttttgcagga ttattaaatg
     6421 acttcacgaa ctcatttgat cagaatttct ttgaagagac gttcgataca cagcttgctt
     6481 atttagtaaa acaactgatt caagaagtaa gtgaagagac gaatgtccat ttttatgaag
     6541 atgaaacttt gtacaaaatg ctgttgactc atttatctgg tgtgttttca agagccgttt
     6601 tacaagaaga gacactgacc aatccgattt tagaaaaaat catggttcaa tacgaggaag
     6661 ttgcgaatgc aatccgtaaa gcagtagagc ggatttttca agaaaaaaaa ttatccgaag
     6721 aagagatcgc ttatatggtc cttcattttg cgaattcatt ggaacgaagt ccgaaagaaa
     6781 gcaatatcag tattgcagga ttttcgccaa gtggattagc ttctactagc atgttggaac
     6841 tacgattgaa aaggtatttt cccttcatcc aacaaattca tttctatcgg attgctgatt
     6901 taaaaaaaat cgatttacaa gaagaatatg atgttgttat ttctacatct attttaccag
     6961 gatacggtgg aaaatatatt ttagtctccc cgctactgct agaagatgaa gtcaagcagc
     7021 taaaagaagc tttttcgcat attgagaaga aaaaaaggca aaaaattacg tataacagca
     7081 ataacgagtg gatgatagaa gatacttatg aggaaacaat gcatttcatg gatcaaatca
     7141 atcaattact cggtcgtttt tttatccaag aactggataa tcctgagacg atttccgaaa
     7201 cgattcgcag cttatttcct tattttcctg aaggactagt aacggatgaa gaggtggttc
     7261 atcgccggct gcttaagcga tatgaacaag cacctatcgg tattcctcat acaaatatgg
     7321 ggttattcca tacatccagc tcattgattt ctaaaccgat cttttgtatt ttcaatttga
     7381 aacatccgtt gaccattgaa gggatggata gacagccagt cgatttgtcc cgtatgttag
     7441 ttatgctggc gccttcgcca atccaagaaa aagacgggat tcttttagga aagatcagtg
     7501 gagcaatcat catgaatgac ttgaacaccg agatcttccg ctcaggaaat aaagaaatcg
     7561 tttatcagtt gttagcgaaa atcctgattg aagaaataaa gaaatgaagg tgaaaagatg
     7621 atacagctac cagcagaaaa aatattgctc gatcaatcct atcaaaattg gaaagaagcg
     7681 ttgaccgaga tcggccagtg gatgacccaa caagggggaa tcaaaccggc atatatccaa
     7741 tcaatgatcg aaagacaaga aaaagcgagt gtctatatcg ggaatttcgt agccttgcca
     7801 catgggactg acaaagatga agaagtagta gaagaaggaa tctatttagt ccaagtgcct
     7861 gatggtgtgg actttggaac aaaagaggaa ccaaaaatcg cgacactctt atttgtagtg
     7921 gctttaaaaa aagaacatca gttagcggtg ctccaagatt tagccttttt ctgttcagac
     7981 atcgaccaag taatggcgct cagtgatgcg gaaaccattg aagaagtcca aatgattttt
     8041 gaacatggac atatataacc aatgttcaca gtaaaaaaag ctgccttgca tcaagtaata
     8101 acttcaacca agataaaaat aagaggagct atttttgttg ggaggttctt attactgcgg
     8161 atgcaagctt ttgaaaacta tttattctag aaaaccgttt atttgaaata ggggacggtg
     8221 acaaggtttt tgtcaccgcc cctattattt ttgtgtttta atagctcttt tttatataga
     8281 tagtgcccat acctatgaat aataaaacga tactccatat accaagtgtc aagataccat
     8341 tcatgaaagt aacctgttct gaagctagtg gcgagaaaat atctcctcct atgatcacat
     8401 tttgaaaatc aacataagaa gttggcaagt aatgactgat tgattctatc catccaatcg
     8461 aagaaaacaa gcgatactct gctaagaaaa gacaaagaag tgtacctaaa agattgacta
     8521 gagaatgttc aaataaagca gatagaagaa aactgattgt acttaaaaag agcacccaca
     8581 acaacaggaa cagaaagctc tggaaaagat actcatacat cggcaggatt cgtatctcct
     8641 gaccaatgat cgttcctaca ggataacgga agtctcccaa accatttttg attattacta
     8701 gtatagagac gatcaaaaat ggcatcacga gacttagcat agctgcacca taataaatgg
     8761 taaaacggat gctatgtttc tttaccatac tatccggtaa tagattgact agagagatta
     8821 cctgctttct tttttcataa gagatgatgg aagaaagaaa caaggcggtt atacataaaa
     8881 tcaaaaaact agaaatcatt cctgaaaaaa tattttcgta gtaatttgct aaagagagat
     8941 gcgctggcaa gtcaaaaata gaatatcttt ggatctgatg ttctttcata taacggagca
     9001 actcgacacg tttttgttgt tcaatgattg gaattccttg tctttgacca gaaatcagtc
     9061 gatccagtat atctttttca taatgataag ttgcttcgac catttgctgg acattccctg
     9121 tgttttttgc atgtaagatt gcttcgatca gtttgttgct tttctctaaa ctttccacaa
     9181 attctttctc attctcatct tctttcaacg tttcaatcaa acgttgcatc tcttcatagt
     9241 tatgattcag ttcatcgaat tctgtataag caagtttatg atcaaaaaaa agtgggaatg
     9301 caaagagcac gaccaacaat agaggaaata aaaagtttac tttgtttttt agtaagagat
     9361 tgcgttcaaa tgtaagtaaa gacatagtta cacctcatat aatttacgat aaatagctaa
     9421 aatctcttcc atatttgagg attctgtgac gatttctcca ttttttagaa aacatgcttt
     9481 agaacaaatc gattggatat tcgcgatagc gtgggaagaa agaagaatcg tcttcccctc
     9541 tttctgccat tgtctgatga ggctattcaa gatatcaata cttcctgggt ctaatccgtt
     9601 caacggttca tcgaataaca tgacagatga atcactgatc aagtaagcag caagcaagac
     9661 atgttgtttc attcctagag acatttttcc aatcggcaaa gtaaggtact cagtcatctt
     9721 caatcgttgg aaaacagttt ggcattctac tttgctctgc caatagtatt tgatcaaagt
     9781 caaataatca acagccgata gatagtcgga taactgattc gttgattcta gaaaaaagaa
     9841 agaccggcga taatctgtat aagcagtagg agagatgttg tgaagggaca attgatcata
     9901 agttgttggc agcagttggg caatgccatt cagcaaagtt gttttgccaa atccgttcgg
     9961 ggcaatcaaa gcagctactt ctcctgattc tactaaaaga ttcaattgtc gaatcacacg
    10021 ttttttacca cgtttcatgt tcatgttttt gatcagtaat gtcatagata ggcctccaat
    10081 ataaaattta ataacataat agaatggaaa acatctaaat taaatgctaa caaaagttat
    10141 tgtttgcata ttataaaaaa attaaaataa cagttttatt taaaattgaa gttttctgat
    10201 accgaaatct ttttattttg ctgacatact caaacctttg gcacaaagtt tcgtgccaaa
    10261 gtacgactat ttctcttttt agtaagcgga tacaattaga gtatcaaaag gagagaggga
    10321 gagacaaaat ggaacggacg attcccaaaa acaacatttc gctaaaagcg agggtacaaa
    10381 aattaggcag tactttatca agcatggtca tgccaaatat tggagcactg attgcctggg
    10441 gtgtattaac ggctctattt atcccagatg gttatttacc aaatgaggct ttcgctacca
    10501 tggtaagccc aatgctaact tatctgattc ctttattgat cggttatact ggcggaaaag
    10561 taattgctgg tgaccgcgga tcagttgttg gggcaattgc aacgatgggt gtgattgtcg
    10621 gaacagatat tccaatgatg ctaggcgcga tgatcatggg acctcttggt ggatatgcca
    10681 tcaagaaatt tgatcagcta ttccaaaaac ggatcaaatc cggttttgaa atgctagtca
    10741 ataatttttc agcaggtctt atcggttttg gattagcgtt attaggtttt tctgcgattg
    10801 gtccagttgt cgatgcattg actcaagcaa tggcaaaagg tgtagagatc attttatctg
    10861 cccatttgat tccattgaca agtattttta ttgaaccagc aaaaatctta tttttgaata
    10921 atgcaatcaa tcatgggatt ttgacaccat tgggaactga acaagtagca gaggctggaa
    10981 aatctattct attcttgctt gaagcaaatc ctggtccagg acttggcgta ttacttgctt
    11041 ttactttgtt tggcaaagga gcagcaaaat cttcagcacc aggagccatg atcattcact
    11101 ttttaggcgg gatccatgaa atctattttc cttacgttat gatgaaaccg ttattattct
    11161 tatcagttat aggcggagga atgtcaggaa gtttcatttt ccaattgatg gatgctggac
    11221 taagagcgcc agcttctcca gggtcgatca ttgcgattct agcgatgaca ccgttcaatt
    11281 cttaccttcc tgttattttg ggcgtgattg ttgccgcagc tgtttcgttt ggtatttctg
    11341 cagtaatttt gaaagcggat gcgaaagata caaatgaaga cttcgaaaaa tctgttcaag
    11401 agacaaaggc agctaagcaa gcttccaaag gtgcccaagg tattcctcaa ggagctacat
    11461 tctctggcgt acaaaaaatc atttttgctt gtgatgcagg aatgggatca agtgcgatgg
    11521 gcgcttcgat cttgagaaaa aaagtacagg aagcagactt gcctcaaacg gtgaccaatc
    11581 aagcaatcag ccaactgaca gatgactcga atacattgat cgttactcag gtcgaactac
    11641 aagaaagagc aaaacaaaaa gcaccgagcg cgcgttttgt ctcagtagaa aactttttga
    11701 attcacctcg atatgatgaa atcattcaag aattaagcag caagcagaaa acatcagttt
    11761 ctgaaattga gaatgagcca gcagaagagt ttctttcagc aaacatcaaa caaatcaaag
    11821 agattctact tgtccacgat gatcgttccg gatcagcaac aatggggatg accgtgctca
    11881 aagatatatt agacaagaac catttaacta tcccgttaag aaaagtcaat atccaagatt
    11941 taaaagatga acctgattca ctgatcgtag ccaaagaaag tttagcggaa aaagtacaga
    12001 tggctgcacc tcaatccatt catttatcag tcaacagcat ggtcaatccg caaaaatacg
    12061 aatcgattgc acaatatttg aaacagacag cttaagggag gaaaacagca tgcaaagttt
    12121 gccattcgac atgatcgagc tcaatcgatc ttttaaaacc aaagaagaag cgatccgcta
    12181 ttgcggtcag atgcttgtag aagcagggtg cgttgatgag gaatatatcg atgccatggt
    12241 agatagagac aaaatgttat ctgtttatat ggggaatttt atcgcgattc ctcatggaac
    12301 agatgaagca aaaaaatatg tgaaaaaatc cggcatctgt gtcgttcaag taccagatgg
    12361 tgtagatttt ggtaccgaag aagaagaaaa gattgcgact gttttgttcg gtattgcagg
    12421 agtcggagat gagcatttgc aacttgtaca gcaaatcgca ctttattgca gtgatatgga
    12481 caatgttgtc cagctagcag acgcgctcag caaagaagaa gtaacggaaa atctagcaat
    12541 tgcttaagga gagagaaaaa tgagagcagt acattttggt gcaggaaata tcggtcgagg
    12601 atttattgga gaggttttgg cagctaatgg atttgagatt actttcgtag atgtgaatca
    12661 cacgatcatt gatgctttaa atgaaagaaa agaatacgaa atcgaattag cagatgaatc
    12721 aaaagaaaaa atcactgtaa aaaatgtcaa aggaatcaac aatcaaacaa atccagaaaa
    12781 agtaatccaa gaaatcgctg aagcagattt agttactacc gccattggcc cgaatatctt
    12841 accttttatt gctgagttga ttgcaaaagg tatccaagaa agagaaaagg aaggaagcac
    12901 aacatcttta gatatcattg cctgtgaaaa tatgattggc ggttcagcat ttctagaaaa
    12961 agaagtgtat aaatatcttc cggaaacatc atttactgac aaatatatcg gctttccaaa
    13021 tgcagcagtc gatcgaatcg tcccattaca acaccatgaa gatcctttat tcgtccaagt
    13081 ggaacctttc aaagaatggg tcattgacga tagccaaaga aaaaataaaa aaatccaatt
    13141 aaaaggggtt ttatatgtag atgatctaga accatatatc gaacgcaaac tatttagtgt
    13201 caatactggt catgcgactg tcgcttatac aggtgccttg ttaggttacc agaccattga
    13261 tgaagcaatg caagatgcgt tagttgtggc acaattaaaa tcagttttgc aggaaacagg
    13321 aagtttgctg attgccaaat gggggtttga tgcagagcag catcatgcgt atattgaaaa
    13381 aatcattcat cgcttccaaa acaaaaatat ctctgatgcg atcacacgtg tcgctcggac
    13441 accattacgt aagttaggtt atcaagaaag atttacacgt ccagtgagag aactacaaga
    13501 acataacttg acttgcccac atttgacggc aacaatgggg attattttta attactatga
    13561 tcctgaagat gaacaaagcc gtcaattgca tgaaatgaag atccatgaaa acttggaaca
    13621 attgattcaa gaagtcacag gaatcaatga tccgaaaaca atcgggaata tcaagcaaaa
    13681 cgtgaaccgt tatgccaagc aagtcgctta aaataggata cgaaaaaggg gaatgtgacg
    13741 aaatttttgt cacattcccc tttttcgaat aactaggctg tttgtccttc aagatagggc
    13801 agatccaatt ctttaccgta acgttgttct aaagctaggc ggatcaaacg agctgccagg
    13861 ttctcatttc ttgcaaggat aggtccatgg aaataagaac cgaagacatt tcggtaaatg
    13921 acaccttcag attggtcttc accattattt ccttgacctt gtaccacttt ccccaaaggt
    13981 cgttcacctt cacctaagaa agtccgacca ttgtggtttt caaatccata ataagtttca
    14041 ttgaattctt cgttatggat aacgatatca ccgataaacc ggttattttc ctgacttaac
    14101 gtgtagtgat ccagtgcact gattccttgg atcttttctc cattagctcc catgtagtag
    14161 tgacctagca attggtagcc accacaaatg gctaacatga cgccatcatt ttcgatatag
    14221 ttgatcaaag aatctttctt tttctggatg tcttttgaaa tgattaattg ctcaaagtct
    14281 tgaccaccgc caaagaaaac caagtcatat ttatcagcat caaaaggttc atgtatacta
    14341 acgatctccg tatggcaaga aacccccatt ttttctgcta tatatttcaa catcaaaagg
    14401 tttccgttat caccatatgt gttcatcaaa tttccataaa ggtgggcgat attgagttca
    14461 taattagcca cggttcattc ctcctttgat aaatccttga gcagctagtt ctttacgaag
    14521 ctgcaataca gcagtgtaag tagctaaaat atagacatgc tcagttggca attctttgat
    14581 tttttcgatt acttctggta attcttttgt ttctgtcaat ttattttctg gaatcccggc
    14641 aacttttaga cgtaaagtca tatctgtatg acggtctcct ccagaaataa cagctgggat
    14701 atccatatcg gcaaagtttt caaaattacc atcccaaatc cagctgacat cgattccgtc
    14761 tgcgtaattg gcatttaata aagccactaa agaaaatgga taaggagcta gaccaatcat
    14821 atcgattact tgattgatac ctacaggatt tttgacaagt actaatgtac attttttccc
    14881 attgatattg atgacttctt gtcggccgaa tactttctcg tcatatccta aaccttgttt
    14941 gattttatca ggatcgacat tgaagtactc tgccactgca gtagctgcta aagcattgta
    15001 gacattatac ataccgccaa cttcgattcc gtattcatga ccatcgatca cgaaatctgc
    15061 tgacacattg tccatccgta ccatatcagt taatcgataa tccaattcag gacgtttgaa
    15121 gtcacaattt ggacagtaat atttccctaa gtttgcataa gtgatcattt tataatgcaa
    15181 gatgtgatga caatttggac ataagacacc gtctgtattg taatgagcca tttgttcacg
    15241 atcttcttca tggtcaaagc cataatattt tctaggattg actgtttcga tagaattgaa
    15301 gattggtgaa tcaccgttac tgataatcgt tgcatttggt gactttgcgg caccgtctac
    15361 aatcatttta taggtcgtat agatttctcc ataccgatcc atttgatcac ggaaaatatt
    15421 tgtaaataag aacagttctg gtttcatata ttctgtgact ttgctcaaac ttgcttcatc
    15481 tatttctagg acagcaaact ttttctgtcc tttttttggt tttgcctgca agaaagtcga
    15541 tacaattccc tgtaccatat tcgcaccagt agggttggtt agaacttcat cgaattgctg
    15601 gcgcaaaata ttgactgtta aagcggtagt caatgtttta ccgtttgttc cggtgacaac
    15661 gacgacttgg tagtcttttg ccaaactatc tagtatatgt ggatcgactt tcagcgctag
    15721 tttacctggt aaacttgatc cgcctttaaa aaaagttttt aatgcccatt gcgacgtttt
    15781 tccaactgca atcgcaaaat gactgcgtat tcccattatg taacctccaa aaacgatttg
    15841 ctgacgaata aattcaacta atcataccat atgttgaaaa aaaggttaaa ttgcttttct
    15901 tattcttaag aaaaggttac ggctgaaagt gcatgaaatc ggacaaaatc gcatgattta
    15961 acaaaaaaac agcttgaaac aaaatgattg tttcaagctg ctgtgatttt attattccct
    16021 cttacctata ttcccatttt aaccgataat aattttctcg cttggatatt catagcctag
    16081 atctcgtgtt tcttttggca cgaataacat caatgtatat agcattccga tccgcccaat
    16141 aaacatcagt gtagcaatcg tgattttgcc cacaacagac aagtctccgg taatccctaa
    16201 agataaacca gttgttccaa acgcagaagt tacttcgatg atgatcgaga tcagcgtttg
    16261 ttcttctgta gcagataaaa aaacgataca aaagaaacac ataccaagag aaagcataaa
    16321 gacaacgact gattttcgca catcatcttg atcgattctc cgtccaaaaa tattgatgtt
    16381 atcttcactt ttgaggaagg aatatagata caaaccgatg attgctacag tagttgttcg
    16441 aatcccgccg cctacagaac taggactgca tccgataaac atcagtaaag aaaaaatgat
    16501 cagtgttgtg atttgaaaat cacccaaatc gtgaatctgc agaccagcat tacgagtcgt
    16561 aatcgaataa aacatcgaat tgatccattt gacactcata ttggaatctt ggaataaatg
    16621 gtccttttcc aatagataaa tcaagacagt tcccgaaaca aacaagatag ataacaaaag
    16681 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16741 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16801 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16861 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16921 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16981 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    17041 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    17101 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    17161 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    17221 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    17281 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    17341 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    17401 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    17461 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    17521 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17581 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17641 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17701 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17761 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17821 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17881 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17941 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    18001 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    18061 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    18121 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    18181 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    18241 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    18301 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    18361 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    18421 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    18481 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18541 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18601 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18661 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18721 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18781 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18841 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18901 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18961 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    19021 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    19081 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    19141 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    19201 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    19261 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    19321 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    19381 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    19441 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    19501 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19561 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19621 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19681 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19741 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19801 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19861 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19921 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19981 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    20041 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    20101 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    20161 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    20221 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    20281 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    20341 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    20401 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    20461 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    20521 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20581 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20641 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20701 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20761 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20821 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20881 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20941 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    21001 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    21061 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    21121 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    21181 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    21241 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    21301 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    21361 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    21421 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    21481 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21541 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21601 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21661 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21721 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21781 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21841 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21901 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21961 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    22021 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    22081 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    22141 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    22201 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    22261 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    22321 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    22381 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    22441 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    22501 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22561 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22621 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22681 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22741 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22801 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22861 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22921 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22981 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    23041 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    23101 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    23161 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    23221 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    23281 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    23341 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    23401 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    23461 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    23521 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23581 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23641 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23701 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23761 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23821 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23881 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23941 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    24001 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    24061 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    24121 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    24181 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    24241 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    24301 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    24361 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    24421 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    24481 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24541 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24601 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24661 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24721 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24781 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24841 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24901 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24961 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    25021 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    25081 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    25141 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    25201 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    25261 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    25321 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    25381 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    25441 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    25501 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25561 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25621 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25681 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25741 aaaaataaaa ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt acaaaacgtt
    25801 tgaccctgat ctttgggctg cgatcgccaa agaagaagaa agacaagaac ataatttgga
    25861 gctgattgcc tctgaaaact ttgtctccga agcagtgatg gctgcacaag gaagtatctt
    25921 gacaaataaa tacgcagaag gttatccagg gcatcgctat tatggtgggt gtgaatttgt
    25981 cgatatcgtt gaaaatttag cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc
    26041 gaacgtccag cctcactccg gctctcaagc caacacggct gcttatctcg ctttggtaga
    26101 accaggggac acgatcttag gaatggatct ttccgcaggc ggacatctaa cacatggatc
    26161 accagtcaac ttcagtggca aaacctatca ctttgttgct tacggtgttg atccgacaac
    26221 agaagttatt gattataatg tggtacgtat tttagctaga aaacatcaac caaaattgat
    26281 cgtagcaggt gccagtgctt acggacgaac gatcgacttt gcgaaattca gagaaatcgc
    26341 agatgaagta ggcgcaaaac tgatggtaga tatggcacat atcgcaggat tagtagcagc
    26401 aggacttcat cctaatccag ttccttatgc agatatcaca acgactacca ctcataaaac
    26461 attgcgtggc cctcgaggcg gcatgatttt gacaaacgat gaagcattag caaaaaaaat
    26521 aaatagtgcg gtatttcctg gtattcaagg cggccctcta gagcatgtga ttgcgggtaa
    26581 agcagtagca ttcaaagaag cattagatcc tgcatttaaa gaatatagtg aacaaatcat
    26641 cgccaatgca aaagcaatgg tcaaagtttt caatcaagca attggaacca gagtcatttc
    26701 aggggcgaca gataatcatc tgatgttgat cgatgttcgc gagttaggta taaatggaaa
    26761 agaagcagag agcattttgg acagtgtgaa tatcactgta aataaaaact cgattccttt
    26821 tgaaacacta agtccattca aaacaagcgg tattcgaatc ggcacgccag caatcactac
    26881 tcgcgggttc aaagaagaag atgctgtaaa agtggctgaa ctagttgtca aagcattaca
    26941 agcaaaagat gataacgctc aactagacga agtcaaaaca ggtgtacgcg aattaactga
    27001 aaaatttccg ttgcataaaa aataaaaatt taaattccat tagtaaacag aaaagttcaa
    27061 tgttgggctt ttctgtttat tttttgggaa aacggattct ttgacaatat cggtgatgct
    27121 ctctagtata tgaggtgtaa ttttagtctt cacactaaat ctcagggagg aaaagtcatg
    27181 actgatcgta tctcgttaga aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat
    27241 ccgcgtatct atgaactagc accggaagaa ggaagagttt tactagaaga agtacaagaa
    27301 tcacctgtga acaaatattc cgtcgatatt gaagacttga tggtggatac tggcgaatgg
    27361 ggaaaactca atattcgtct cgtacgacca gaagggaata tggataaatt accagttatt
    27421 ttttatattc atggagcagg ctgggttttt ggcagtgctc aaacccatga taaattgatc
    27481 agagaacttg cggttcgtac gaattccgtc gttgtctttc cagaatatag tcgatcacca
    27541 gaagcaaaat atccaacagc aattgaacaa aattatgctg tgttgcaaca gctgaataaa
    27601 ttagccaagt caaaaaatct ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt
    27661 ggtaacatgg ctacagtcat gacgatctta acaaaagaac gaaagggcct cccaatatcc
    27721 aagcaattgc tgtattatcc agtcacaaac gctgattttg atacagattc ctatcatgaa
    27781 ttcggagaaa actatttttt gacaagagaa ggaatgatgt ggttttggga ccaatatacg
    27841 acgaatgaag aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa
    27901 ctaaatgatc ttccttcagc aatgatttta acgggagaag cggatgtatt aagagatgaa
    27961 ggtgaggctt atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca agtacgcttc
    28021 caaggaatca tccatgattt tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt
    28081 gcagcaatgg cattatctac ttcttggatc aagaaaaaag aataagcttt gcttgtccgc
    28141 aggaaaactt cttttcaaaa acggattttc ttaggaaaaa tggcgagttt gactagtcaa
    28201 tcacttgatt ttgttttaca attaaaaaga aacgacagaa caaaggagag cttaaaaaat
    28261 gggcaaattt caagtgatcg atcatccatt gattcaacac aaactaacta ttattcggga
    28321 caaaaactgc ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta tgttgatggc
    28381 atatgaagta tcacgggata tgccattgga agacatcgtg atcgaaacac cgatcactga
    28441 aacaacacaa aaaacgttgt ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg
    28501 tattggaatg gttgacggta tcttggaatt gattccagct gctaaagtgg gacatatcgg
    28561 tctttatcga gatgaagaaa cattggaacc acatgaatat ttcgtcaaac ttccagaaga
    28621 cattgatgca cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat
    28681 catggcaatc gatgcattga aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt
    28741 agcagcacct gagggagtaa aagctttgca agaagcgcat cctgatattg acatctatac
    28801 agcttctcta gatgaaaaat tgaatgaaca tggttatatc gttcctggac taggggatgc
    28861 gggtgaccgt ttgtttggta caaaataagt aaatacgaaa aagggtgtga cacaactttt
    28921 gtcacatcct tttttggtca tttttaacgt ttgatgcaga acagcttttt cacagctttc
    28981 gtttgcatat aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa atctttttta
    29041 gttctttgta gttaacgatt actacaccct tactttgcgt catcaagttc gcattttctg
    29101 cagtttcatc aatctcaaca acagcggaat ttttcaattg ctttgaaatc gttccagttt
    29161 gcgacttgcc gtgaattgtg aacattacgt gagtattgat cttgaatttt tcaccaattt
    29221 ccgatggtac gatagttgta tcaaattttc caaaagttgc cattttcata aaacctgcct
    29281 ttcacatcaa ttataccacg ttttatgaaa aatatcatga aattaaacta attttccatc
    29341 ggactcttta caatcagcca aatagagtat ataatttctt ttggataagg ccagcttagc
    29401 tcagttggta gagcaacgca ctcgtaacgc gtaggtcgta ggttcgatcc ctatagctgg
    29461 cattaaaaga gaagacagat atatcaagga tttttaatcc attgatacat ctgtcttttt
    29521 gtttaaagga aataaagtat gctttcttag caatagagca tgtattattt ctataaaaat
    29581 ttaggagaat aaaacgacta gcaatatagc tgtgaaatca aatatcacat gaactgccca
    29641 acttgtaatg atcgagttgc ttttaatggc agcttggttg aataacaatc ttgccacccc
    29701 ttgtatcaaa aggatgtgtg ctacagtgtg taaaatattt ccattatcat aagtactgta
    29761 atggataaat ccaaagatga ttgctgacaa gaaactagcg acaggaatgc tgaacttact
    29821 agaaaaaata gcgagaaaat acactgagaa caattcttct ccaagtatca tgataggcaa
    29881 aataataaat aataacgggc tgaaagcctc atttattgga ttgcctgtta aaccccattt
    29941 caaaatttgt tgcaaaaata ccgagactgc ggcactgatt actacattga taaaaaaata
    30001 tttggctata tttttgacag gagcgacagg tttcgagaac atttttttcg tatctttttt
    30061 accaaaaaca agtgtaaatg ctataaatcc agtgatagtt aaagaaaaaa tgctaataat
    30121 ggatggcgca aatagcaacc ctaacaaacc gagtacaacg acaatagtgc ccaatatccc
    30181 ttttttaagt tctatttttt ttcctaaaat gttattcatg ataataactc ctactattca
    30241 gtttttgaag atagagtcag tatacatgaa gagttaaaat aggcaatgtt tttttatgga
    30301 tatttgtatt gctaaaaatt tatcttatat attcattttg attatactac ttttatttgt
    30361 aaaaattttc tagcaaaacc aagtgcttgc aactgattaa gcgtacaatt ttttagatgt
    30421 tccgagcgta cttcaatcat ttcaaaggag ttgctactta aatcgatatt ttttaaatca
    30481 gtatcaaaaa agctagcatt ttctaaatca ttagtagaaa acattatttt agtgagggaa
    30541 cagtctacaa aatctgcgct tgataagaca gagtgctcaa aggtactttc ttttatgttt
    30601 gaaccagata aatttacata gtccatttta caattctcga ataacgtgtt cccaatataa
    30661 ctttccatca atttagtacc tgttaattta caattgacaa atttcacgcg atgcaacatg
    30721 ctttttgtca atatacagcc tgaaaaatca cagttttcga atatacagtc ggtaatctcc
    30781 attctttgaa aatcattgga agcaaaaaat gcatacttga aaatagattt gtaaataatt
    30841 ggatggcaga ttatttggtt ttcgatgacc tctttttgtg aaaggatatt atacagttca
    30901 aaatcttcgt tttcatagat atgaaaaaag gatcctttat tcaagcttgc ttcattaact
    30961 ttaggaaaaa tcatatttaa ttacctccat tttcataaag tcatattaac aaaagctaaa
    31021 ccaacttaca ttagcagaaa atgagatagg ttttcgcctt tttcgataac gatagtgtcg
    31081 ctatctcttg aaacgttctt agaattgccc tgagagacac aaattaggcg taattctaat
    31141 aaaaatctta gaataaaaat ttttactgat ttaatttaga atgtttttaa aataaaaatc
    31201 gttgccataa cagtgtattg aaaggtttta acaatccagt aatgatttaa aaaaatctag
    31261 atgtagcgta tactttgttt atagaatgta gtgggaagaa atatattttt gggaggaaat
    31321 cgtgatgtct aaaagtgaag aaatagaaaa catggtacta aaattatatg atctcgtttt
    31381 aaatccagag atcaaagaaa aggaacgtat acttttgata gacgcaaaga caggcttaga
    31441 aaaaggtcag tattatccta aagtcataaa taatttggaa cgtagtttac gtccgttagc
    31501 aatcagggga gaattgtcta aaccagtatc accgttttat atggagatat caacaatagg
    31561 aaaatttgaa aaagaattag gtcgaggaat ggcttcggca ccgattactt ttgggcattt
    31621 ataaaaacga gttattcatc tcaatgaatt aaaaagtata gtcaatctca taatgcaggc
    31681 taggttcatt tatttgaaca gagtctgtat ttttttattc taaataaaga aacagatgtt
    31741 tctttatatt gtattttatc ctttaattaa cacaaaaac
//
LOCUS       DAJSMK010000024        30334 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.024, whole genome shotgun sequence.
ACCESSION   DAJSMK010000024 DAJSMK010000000
VERSION     DAJSMK010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30334
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.024"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            82..564
                     /locus_tag="ON488_001125"
     CDS             82..564
                     /locus_tag="ON488_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231330.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            761..1651
                     /locus_tag="ON488_001126"
     CDS             761..1651
                     /locus_tag="ON488_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HCR3231331.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            1976..4447
                     /locus_tag="ON488_001127"
     CDS             1976..4447
                     /locus_tag="ON488_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCR3231332.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(4550..6286)
                     /locus_tag="ON488_001128"
     CDS             complement(4550..6286)
                     /locus_tag="ON488_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HCR3231333.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(6283..6987)
                     /locus_tag="ON488_001129"
     CDS             complement(6283..6987)
                     /locus_tag="ON488_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3231334.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7118..7621
                     /locus_tag="ON488_001130"
     CDS             7118..7621
                     /locus_tag="ON488_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HCR3231335.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            7581..7919
                     /locus_tag="ON488_001131"
     CDS             7581..7919
                     /locus_tag="ON488_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HCR3231336.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            7940..9358
                     /gene="ffh"
                     /locus_tag="ON488_001132"
     CDS             7940..9358
                     /gene="ffh"
                     /locus_tag="ON488_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HCR3231337.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            9470..10048
                     /locus_tag="ON488_001133"
     CDS             9470..10048
                     /locus_tag="ON488_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HCR3231338.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10052..10573
                     /locus_tag="ON488_001134"
     CDS             10052..10573
                     /locus_tag="ON488_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCR3231339.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(10652..11206)
                     /locus_tag="ON488_001135"
     CDS             complement(10652..11206)
                     /locus_tag="ON488_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCR3231340.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            11459..11734
                     /gene="rpsP"
                     /locus_tag="ON488_001136"
     CDS             11459..11734
                     /gene="rpsP"
                     /locus_tag="ON488_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HCR3231341.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            11746..11997
                     /locus_tag="ON488_001137"
     CDS             11746..11997
                     /locus_tag="ON488_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HCR3231342.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12121..12912
                     /locus_tag="ON488_001138"
     CDS             12121..12912
                     /locus_tag="ON488_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231343.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13082..13603
                     /gene="rimM"
                     /locus_tag="ON488_001139"
     CDS             13082..13603
                     /gene="rimM"
                     /locus_tag="ON488_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HCR3231344.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            13593..14354
                     /gene="trmD"
                     /locus_tag="ON488_001140"
     CDS             13593..14354
                     /gene="trmD"
                     /locus_tag="ON488_001140"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HCR3231345.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            14490..14837
                     /gene="rplS"
                     /locus_tag="ON488_001141"
     CDS             14490..14837
                     /gene="rplS"
                     /locus_tag="ON488_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HCR3231346.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15210..15872
                     /locus_tag="ON488_001142"
     CDS             15210..15872
                     /locus_tag="ON488_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231347.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            15951..19178
                     /gene="fss3"
                     /locus_tag="ON488_001143"
     CDS             15951..19178
                     /gene="fss3"
                     /locus_tag="ON488_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HCR3231348.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITDAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            19292..19606
                     /locus_tag="ON488_001144"
     CDS             19292..19606
                     /locus_tag="ON488_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231349.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            19619..19993
                     /locus_tag="ON488_001145"
     CDS             19619..19993
                     /locus_tag="ON488_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231350.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            20003..20347
                     /locus_tag="ON488_001146"
     CDS             20003..20347
                     /locus_tag="ON488_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HCR3231351.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            20418..21770
                     /locus_tag="ON488_001147"
     CDS             20418..21770
                     /locus_tag="ON488_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCR3231352.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFWVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            21830..22972
                     /locus_tag="ON488_001148"
     CDS             21830..22972
                     /locus_tag="ON488_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HCR3231353.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            22997..23251
                     /locus_tag="ON488_001149"
     CDS             22997..23251
                     /locus_tag="ON488_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231354.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            23507..24691
                     /locus_tag="ON488_001150"
     CDS             23507..24691
                     /locus_tag="ON488_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCR3231355.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            24688..24825
                     /locus_tag="ON488_001151"
     CDS             24688..24825
                     /locus_tag="ON488_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HCR3231356.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            24830..25051
                     /locus_tag="ON488_001152"
     CDS             24830..25051
                     /locus_tag="ON488_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231357.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            25064..25564
                     /locus_tag="ON488_001153"
     CDS             25064..25564
                     /locus_tag="ON488_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCR3231358.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            25661..27508
                     /locus_tag="ON488_001154"
     CDS             25661..27508
                     /locus_tag="ON488_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HCR3231359.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            27511..28407
                     /locus_tag="ON488_001155"
     CDS             27511..28407
                     /locus_tag="ON488_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3231360.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNFYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            28457..28846
                     /locus_tag="ON488_001156"
     CDS             28457..28846
                     /locus_tag="ON488_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3231361.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            28833..>30334
                     /locus_tag="ON488_001157"
     CDS             28833..>30334
                     /locus_tag="ON488_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR3231362.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTDALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPLSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKG"
BASE COUNT        10128 a         5200 c         6499 g         8507 t
ORIGIN      
        1 aaaaaaagtt tttcccccta atttttttag atagaaaatt gtatagtatg atgagagaaa
       61 aagtagtttg ggggaacgtt aatgagaaga aaagcagtaa tcgatcggct ttatttattt
      121 ttttggtttt ttcctatcgt tttgctacct tttacatggg taaatgctgt tgtacaaggt
      181 gcggagatat taggcctgat ccaaggaagc ggatttgtgg tttctaggaa ttttccagct
      241 ttgactgttt tctatttagt gataagtgta ggtctcttat taccaaaatc tctgatcaat
      301 cactacaatt ggcagctgct ttacttttct tgcttattag tatttacatc tatgttttct
      361 ttgctgcctc gcttgattat cggccctaat ggtttgagcg agagtggatt gaaggattca
      421 gcttattcct ccatgtattt cttgacgatc aaaccatggt tctatttagt aattgcctca
      481 tttattcttg caacattttt ttacttctgg acagaaatca ggataaaaag tgaacgatct
      541 gtatctataa aaaataacta ttgatggtgg atcatcagta aaaaagcata tgagctgcgt
      601 aaaatgcatg tttctcatat gcttttttta ttattatgta aagaatgcga aaaacgttta
      661 catgattttt acataactta actatatttt tacagcaacc atacgaggga tttacagtcg
      721 actgataaac tttagttgta aataagaaag gagcaataaa atgaaaaaag tattgtttac
      781 tctaggtatg atgggaattc ttttagccgg atgcggctca ggatcaggaa atacagatgg
      841 ctctgccaca caaaataatt caagtgactc aaatgaacaa gtaaaaatcg ttgcggtagg
      901 ttcgacagca ttacagccgt tagtcgatgc agcacaagaa agctttgtac aagaaaatcc
      961 aaattatcaa atctctgtac aaggaggagg aagcggaact ggtttgagcc aagtcgaagc
     1021 tggagcagtt actatcggaa actctgatgt atttgcagaa gaaagagacg gagttgatgc
     1081 ttcaaaatta gtggatcata aagtagcagt ggtcgggatg gcgccaatcg tcaataaaga
     1141 tacagatgtc aaagatatca ccaaacagga attgattgat atctttacag gaaaaatcac
     1201 taactggaag gaagttggcg ggaaagatca aaaaatcaac gtcgtgaacc gtgcaaacgg
     1261 cagcggtacc cgcgcgacat tcgaaaaatg gggactggat ggtgctaccc ctgtgcagtc
     1321 ccaagaacaa gattcatcag gaacagttcg gcagctggta agtcaaacac caggagcaat
     1381 cagctattta gctttctcat atctcgatga ttccacacaa gcactaagta tcgacggtgt
     1441 agaaccaaaa gaagagaatg tagcagataa cagctgggga atctggtcat atgaacatat
     1501 gtacacgaac ggaaaacctt cccctgaagt ccaaaaattc ttagactaca tgatgacaga
     1561 agaaatccaa gaaggacctg tcaaagaatt gggctattta ccaatcacaa tgatggaagt
     1621 agaacgtgat cacgaaggaa atatcaaata actagcagat aaacatgcca cggtagtcgt
     1681 tactattaag gaaaaatcaa ctatgtttcc cacatataca tttttccttt aattgtgaaa
     1741 aatagttcct catattttgc cgttttttga gctaataccg agggtcagct gattaaacac
     1801 cgtttattcg aaaaaaagag ctacgacata gaactgtcgt agctcttttt ttgctatatg
     1861 acaggaatga aaggtgtttg caagcttaat gtgaggaaca ctttccatat ctgttctata
     1921 ctggatagga gaagtttgga aatatccaga aaacgaaatc aatcgaggta gccacatgaa
     1981 gaataaatgg ataaatcgaa gtaaaaaaaa gaaagtaaca caaagatcat cagataaagt
     2041 catccgtctt tttccatcgt ataaagaagg attaacggca gatcaagtca aggaacgaat
     2101 agaaaaaggt gcagcaaata attcagtcga tcccacattc aaaacaaatc agcaaatcgt
     2161 attggaaaac atatttacgt atttcaattt gatctttctt atcttagcca ttttgctttg
     2221 tttagtagaa tcctataaga acttgacttt tttaccagtt atcatagcca atacaggaat
     2281 cgccattttt caggaaattc gatccaaaaa gatcttggac gaactaaatg ttttaaatac
     2341 agcaaaagtc aatgtcatac gggacgggat agaacaaaca atagatatag aagaccttgt
     2401 aatagatgac attgttattt tagagactgg acatcaaatt ccagcagatg cagaggtcgt
     2461 ggaaggaaaa ctgcaagtta atgaggcttt attgacaggc gaagcagatg aaataaccaa
     2521 agaaataggc gatccattaa tgtccggcag tttcattgtt tccggaaaag cttacgcccg
     2581 attagacaaa gttggagcag attcgtatat ttcccagctg acagtcaaag ccaagacaat
     2641 gggagaagga gaacagtcgg agatgattgc ttctcttaat caattgatca aatggattgg
     2701 gatcatcatt attcctatcg gtatcctgct tttttctcaa agttactttt ttaatggaaa
     2761 cacgatcaaa gaaagtgtcg ttgcaatgga agcagcattg atcggtatga tacctgaagg
     2821 actgtacttg ctgacgacga ttgcattagc attaagtgcg actaaactag caaagcaaag
     2881 agttctttta cacaatatga aaagcattga gacattggca agggtaaatg tcctttgtgt
     2941 agataaaaca ggaacgatca cagaaaataa aatgtctgtt caaaaagtga tcgtctctaa
     3001 aaaacaagaa ataatcagtc agtcagatca attggaagca tgcattgctg actatgcaaa
     3061 agcgatggca ggagacaatg caacaatgga agctgttaaa gcatatttta caaaaaccac
     3121 tgatcaatcc tatcaccatg ttattccttt ttcttctgtc caaaaattca gcagtgtagc
     3181 gttggcagac aaggtgtatg ttttaggagc gcccgaaatg gttttgcgcg atcaattgcc
     3241 ggaatatgcg gaagagtttg tttctttcgc tgaaaaaggc tatcgcgtgt tggtctttgg
     3301 tgtgtacgat gggattcttg aagaaccagt attgacagaa gcagtcacac cattaggcta
     3361 tattctgatt gctaatccta tcagaaaaga agcaagagcc acatttgatt acttcaaaaa
     3421 acagcaagta gccatcaaag tgatttctgg agataatccg ctcaccgtat ccaatgtagc
     3481 tgtccaagca gggatttcac atgctgatca gtacgttgat gcatctaaat tatcagaaga
     3541 agaatatgaa gcagctgtcg aaaaatatac agtttttgga cgcgtcaagc cagaacaaaa
     3601 gaaaatcttc gttcaattga taaagcgtaa caatacagta gctatgacag gtgatggcgt
     3661 gaatgatatt ctagccatga aagaagcaga ctgcagtata gcgatggctt ccggaaatga
     3721 agccgccatg caggcctcac aagtggtctt acttgattct gacttttcac gcatgccaga
     3781 agttgttgca gaaggacggc gcgttgtgaa caatattgag cgatcagcca gcttgttttt
     3841 agtgaagaat attttctcct ttttgctctc actgttttca gtgatctttg ctctgaccta
     3901 tcctttagaa ccatcacaaa tcacattgat tagtttgttt actatcggac ttccatcttt
     3961 cttgcttgct ctagaagaaa acaaaaagcg aatcagaggg aaattcatca tgaatgtgat
     4021 ggaaaaagct gtgccaggtg gactaacaga tatgatcgta gtcggtgcgt tggtgatctg
     4081 cggggtgact ttgaatctaa ataaaacaga tgtttctaca gcatctacca tgcttttgat
     4141 tgcagtaggg ttcctcgttc tctataaaat ctgttcaccg ctgaataaat tcagaagtca
     4201 gatcattctt ttctgtgcta gcggtaactt tttttcggtc atctttttgc ataagctgtt
     4261 ttcaatcacc ggtatctcag ctgtatcact tttgctgttg agcattctat ttttctcggc
     4321 agattcgatt tttaggcatt tgaccacatt ggtagaatat ttgtttgaac gtaaaaatga
     4381 aaaagagcaa aagccgttta gtcgcgtagc taaaaaattt ctatcgatat ttaaacgaga
     4441 aaattgacga aaagtatctc aaaaaagagt aaaaaagaac aaccactcgt gtatctttcg
     4501 aagcaggatg agtcatccaa ctttaaaacg cacgagcagt tgctcttttt tacattttcg
     4561 gaatggtaac ggtgaaagtc gaacctgttc caagatgact gtctacagta atcgtaccat
     4621 taaggagttg cacgtagtct tttacaatcg ctaaccctaa tccggtcccg cctgaatgtc
     4681 ggcttcgcgc cttgtctacg cggtaaaaac gctcaaagat ccgttcctga tcctcaatgt
     4741 cgatacctat accaaagtct tggacagaaa acgatagatc atctgttgcc tgatagcgga
     4801 taataatctc gctgtcgctt tttgaatatt ggacagcatt ttcaatcaga tttttgataa
     4861 ttggataaag gatatctgtt ttagtagtaa atggttcgtt ctttccaatc aatcgaatcg
     4921 tcaaccgttt cttttcgatg attggctgat aattttgaac gatttgctgg aaataaggtt
     4981 ctgtataaat tgtctggatc tcgtaagaat tctcgccatc ttttgacagc tggatgattt
     5041 cccgaatcag tttatctaac cggatcgcat ctttttgcat gatctcaaga aaagaagtca
     5101 gagtttgcgg gtcatctttt gcaccatcca gtaaagtctc ggtaaaacca atcagtgaag
     5161 tcacaggagt ttttaattcg tgagagacgt tgccaacgaa atccttttgt agcttttcta
     5221 aacgtcgcac tttcgttaag tcatacgcca cccctagaat ctgtccggta ccttctgaat
     5281 tagtaaagta gcgcaaactc aagtctaatg tctgccgacc ttctgtaagg gtgatctcct
     5341 gatggatcag cggatgctca ggagtcactt gatgaatcag ctgaatgagt tttggctctt
     5401 gaatgacttc tgtgtaccgc tgttcaggtt gatagcttac cacgtttaaa tgtagctgca
     5461 tctttggatt aagcagtagt aaacgagaat cagcatcatc aatcaggaat acgccaatca
     5521 tcagttcgtt cagtaacgta tataattgct cttctgtggt agtacacgcc cgatacatct
     5581 tactcatttg ttcgctcaac gcattaatcg tctgatacaa ttcttcccat tgatcgggtg
     5641 tttgcatgat tacttccgcc tgattaggat tttgcaccat tttttttagt acgggcagca
     5701 cggttttcaa tggctggttt ttttgataga tcagataata gatcattcct gcaagaacaa
     5761 ggaagaaaga cagaaagaag aaaaagaccc aacggcgaaa actctcagtt ctcggtaaaa
     5821 aaccgcttgt cggttctgcg atacgtaaaa tggcttctaa ctggccactt tttttgactg
     5881 gtaatgcgac atataaaaga tcctcattca aagtagtact tttgcgcaaa gcgctaccta
     5941 ggttcccacc attcaatacg gctttgattt cgggacggga gtttcgctgt tcattcaatg
     6001 tttcattgtt tgtgtcaaat aagatctttc cagtagcatc cattaaagta atccgttcgt
     6061 tcgactgatg gacgaattct tccaaagcag ttttgttttg cgctgcttgg aggttttcga
     6121 catctaattg ccggatcagc agttgtgctt tttttgtcag gtagctttct tgctgttcca
     6181 cgatctgctg ttgaaaataa tgggaaatca attgccagcc accaaaaaac aaactaacta
     6241 aaagaataag aaagaagaga cgttcataaa tttttttcca tttcatcgtt ttggttcctg
     6301 aaacttatag ccaaatcctc taatagtcac caagtacttt ggatgttttg gatctcgctc
     6361 gattttttct cgcaaatgac taacgtgtac atctacgatt cggctttgtc ctgcgaagtc
     6421 aaaattccaa atgcggtcta gcaatgtgtc tcggtcgatc acacggtctt ttcgtttcat
     6481 gaaataaaca agtaattcaa attctttcgg tgttagttca atcagatggt cgtctacggt
     6541 cacttgataa ttggtcaaat cagcagtgat ttgtccaatc gatagatatt caggctcagc
     6601 ttcatctttt gattgcttac gaggttcaat ccgtctgaat attgctttca tacgggctaa
     6661 tacttcgcga ggactaaatg gtttggtcaa atagtcgtca gcacctattt ctaggccaat
     6721 gatccgatcc acttggtcat ctttagccgt cagcatcaaa atcggtgttt catttttttc
     6781 ttgacgcagc cgctgagtga tctccatgcc atccatcgtt ggaagcatca catctaaaat
     6841 gatgaaatca aatgattgtt ctaatgctaa ttctaatcct tcgcctccat ctgtggcact
     6901 ggttaccttg tagccttctt tttccaaatt gaacgtcaag agcgttacaa tagaaggttc
     6961 atcatcaaca actagtattt ttttcattca aatctccttt aaataggttt cattctgttt
     7021 atattttagc atagaatcag tacaaagggc tattttacaa aagaaataaa tggtataata
     7081 ggaaggcact ttgctgaata gaaaggaaga gcagtcaatg attggaatca gtgcatgttt
     7141 aggcggtctg gcctgtcgct atgatggaca gaaaaaagaa gtaccagaat tgatggaact
     7201 agttgaaact ggagaagctg tcatggtctg tccagaagtg atcggcggat taccaattcc
     7261 tagagatccc gctgaaatca ttggtggaaa tggattcgat gtgtggaaag atcaagcaaa
     7321 agtatggacg acaagcggcg aagatgtaac ggaagcgtac aaaaatggcg cgatcaaagc
     7381 ctatcaaaaa ttgcaggaaa aacacattga tctagtcatc atgaaggaaa aaagcccttc
     7441 atgcggaacc cattcgattt atgacggaag tttttccgga ataaaaaaaa atggtgccgg
     7501 agtggctact gcttatttta ttcagcaaaa aatgactgtg ctctctgatg aagaatggct
     7561 gaaaactaga ggtgagcaga atggaaatcg aaaagaccaa tcgaatgaac gcgctctttg
     7621 aattttattc gaccttattg acagaaaaac aaatgaacta catggaatta tattatgcag
     7681 atgatttttc attaggtgag atcgcggaag aatacgaagt aagccgacaa gcagtatatg
     7741 acaatatcaa gcggacaagc aagatcttgg aggattatga aaaaaaactc catctttttt
     7801 ctaattatat tgttcgagaa caggtattgg aaaatatgac tgcatatatt acagataagt
     7861 acccggaaga taaaaaacta cttgaatatg tacagcaaat tcaagcaatc gaagaataaa
     7921 taaaaggaat gaagaaaata tggcatttga aagcttaact gaacgtctcc agcaggcgat
     7981 gggaaaaata agaaaaaaag gaaaagtatc agaagctgac gtaaaagaaa tgatgcggga
     8041 aatccgcctt gccttactag aagccgatgt taacttgcaa gtagtcaaag attttactaa
     8101 gcgcgtacgc gaacgtgcgg taggggcaga agtgctggaa agtttatcac ctgcacaaca
     8161 aatcgtaaaa atcgttgatg aagaattgac gatcacactt ggttctgaaa cagcagagtt
     8221 aaataaatca ccaaaaatac caactgttat catgatggct ggtcttcaag gggcaggtaa
     8281 aacgaccttt actggtaaat tagccaatta tttaaagaaa aatgaaaatg ctcgtccgct
     8341 cctaatcgca ggggacgtat atcgaccagc tgcgatcgac caattgaaag tattaggtca
     8401 acagctagac gttcctgtat ttgatatggg aactgaagtc agcccggtag agatcgtccg
     8461 tcaagggatg gagttagcaa aagaaaagaa aaacgactat gtattgatcg atacggcagg
     8521 acgtctgcat atcgatgaaa cattgatgga tgagttgaaa caaatcaaag aattgacgca
     8581 accaaatgag attttgcttg ttgtcgatgc catgactggt caagatgccg tcaacgtagc
     8641 tgatagcttc aaccagcaat taggtattac aggggtcgtc atcactaaac ttgatgggga
     8701 tactcgaggc ggggcagcac tatcgatccg ctcagtgaca ggcgcaccaa tcaaattcat
     8761 cggttctggt gaaaaattga ctgacttaga agtattccac ccagatcgta tggctagccg
     8821 tatccttggt atgggggata tgctgacatt gattgaaaaa gcgcagcaag actacgacga
     8881 gaaaaaagcg gaagaacttg cacagaaaat gcgggaaaat tcattcgatt tcaatgactt
     8941 tattgaacag cttgatcaag tgatgggtat gggcccactg gaagatctaa tcaaaatgat
     9001 cccaggaatg aatcaagtcc ctggaatcga aaacgtcaag gtagatccaa aagatgttga
     9061 acgcaaaaaa gcgatggttt attctatgac gccagcagaa agagcaaatc ctgatctgtt
     9121 gaacccaagc cgtcgtcgcc gaattgctgc cggttctgga aacagtgttg ttgaagtgaa
     9181 tcgaatgatc aaacaattca aggaatcaag aaaaatgatg cagcaaatgt ccaaagggga
     9241 tatgaacatc ccaggtatgg accaaatgtt tggttcaggc gtcaaaggaa aactaggcaa
     9301 aatggcgatg aatcgaatga tcaagaaaaa taagaagaaa aagaaaaaac ggaaataaga
     9361 tgaaaaaaac agcttcggta cagactgaaa atgtctactg ccggagcttt tctatcagca
     9421 atttttattc tttactaata caattactct aaacgaagag gtggcacaga tgagatgtcc
     9481 gtggagtgaa caaacagaaa gtatgcggca atatcatgat actgtctggg gtgttcctga
     9541 atatgatgac caaaagctgt tccgaaaatt gatgcttgat attaatcaag ccggattgag
     9601 ctggcagacg attttaaata aaagtgaagc attcgatgaa gcatatgatc gattcgatat
     9661 caaaaaagtc gcaaattatg gagaaacaaa aatcagtgaa ctaatggaaa acaaaggaat
     9721 tattcgtaac cgaagaaaaa tcgaagcagc cgtccaaaac gccaaagcag tcttgaaaat
     9781 tcaagaagaa atcggcagtt tttcagagta tctttggtcg ttttctaatg gaaaaatcgt
     9841 tgattcttct tatcattcac aagaagaagt cccaacaaca agtcctcttt cagatgaatt
     9901 agcaaaagat ctaaagaaaa gaggatttaa atttatcgga agcacaacaa tctatgcttt
     9961 tttagaagct gtcgggatca tcaatgatca ccttgacagt tgtttccgca aagaagaggt
    10021 cgtacgtatc ggcagaaagg gcgaataaag catgcgaaaa atcatatttt atggtgctat
    10081 aagtttagat ggctatttgg caacgaaaac ggatgatctt caatggcttt ttgacactcc
    10141 aacaggtaag caaactactt atgaagcttt ttatgaaaca atcgatacga ccatcatggg
    10201 cagaaaaact tatcaggaag caaaaaaata tttggagacc gaagcaattt atccagagaa
    10261 aaagaatttc gttttttcca cccacgcaca attacaattg ccagatgctg aggtcgtaaa
    10321 cgaagatcct gttgcttttc taaaaaatct acaaatgaca gaaggaaaag atatctgggt
    10381 tgtgggtggc ggtcgattga tcaaaccgct attggaacat caaatgattg atgaatggta
    10441 tatccagatt acccctgtat tattagggga cgggattcct ttattccaaa aaggaacata
    10501 tgaagcgcgt tttgaaatgc tagacacgac acgattcggt gaatttatcg aattgcatta
    10561 tgtacgaaag tagaagtaaa taaaataaaa aaggcaacta tatgcagaaa tgtcctgtac
    10621 atagttgcct tttttattac cgttatgctt tttactctgt taatttgtta gaaaaatcta
    10681 gatacgcatc taaaatcgtt tggaagaaac ttaatgttcc ttcaacgata ttaccatttt
    10741 catcaattag attcgcaacg tttccgatat atgcttccgg ttgctgcaag gttggcacat
    10801 tcaaaaagac aagtgattgg cgtagatggt ggtttgcgcc aaagccgccg atcccacctg
    10861 gtgatgcagt aacgactaaa cctggtttat gatcccaaac actgtgtcca taaggtcttg
    10921 agcctacatc taaagcattt ttcaatactg ctggcacaga acggttgtat tcaggagtaa
    10981 cgaaaacgac accgtctagt cccctcactt cctcacgaaa acgagtccat tcagcaggag
    11041 cctgttctgg agtttcgaga tcctcattgt aaaatggcag atcatcgatt tttacaaata
    11101 cactttcgta cccttcagga agcaatttcg caaaagcttc tgctactttt ttgttgtaag
    11161 aatcttttct taaactacca ataaaaaatc caattttttt tgtcatacga tttttcctcc
    11221 ttcaaactat ctataataat cttacaaaag ataagtaact ggagcaaata aaaacactta
    11281 ctgacaaaag ctacatagaa gatagattac ttatttttaa caaaaaagaa gtctaaaatc
    11341 ttctattttc taaaaaaaat cgaatttaat caagctgtaa agaaaaaaag ctttacaggg
    11401 taaaaaaaaa ctgttacact acatcttgtg aataaaacaa tggaggtgga aataaataat
    11461 ggcagttaaa atccgtttaa aacgtatggg ttctaaaaag agtccgtttt accgtatcgt
    11521 cgtagctgat tcacgttctc ctcgtgatgg acgtttcatc gaaactgtag gtacttacaa
    11581 tcctttgaaa gaccctgcag aagtagtttt aaaagaagac ttagttcttg actggttatc
    11641 aaaaggtgca caaccttctg acactgtacg taacatcctt tcaaaagaag gcgttatgca
    11701 aaaacaccac gaagctaaat tctcaaagaa ataaggtgac cggatatgaa agatttaagc
    11761 gacttagtct taacaatcgt tcgtccgcta gtcacttatc ctgatcaagt caagttagac
    11821 gtcgtagagt cgaaagactt ttacgagtac aatctaacag tggctcctga agatattggc
    11881 cgtatcattg gaaaacaagg gcgtgttgct aaagcaatcc gcacaatcgt ttacggtgtt
    11941 cggatcaatg caccgaaaaa agtgcgtttg aatatcatcg atgataagga aaagtaaata
    12001 aacgtgctgt actcgaattt tcgagtgcag cttttttgtt tttttattaa ttgaagaaat
    12061 gattatttgg caaaacaagc aagaaagcgt atccttatag gaggagggag tgaacagcca
    12121 atgagaaaga aaatgttatt tattccattt gctctattgt taagcgcttg tagttcggtt
    12181 actcaagaat cagacaatac acatctatca agcagtatat ctgaaactgt taccagtcca
    12241 gaaaaaagta gtaccaaaac ggcttccacc actgaacaaa caatggctac ctcaaataat
    12301 gagaaaaaga ctgctttaga ccagttgaaa gaacaacagc caaatgttcc catgcctcta
    12361 gatgtaccag tctcttcagg ctatctcaat atcgcagcga cacatacaaa gcaaggttat
    12421 tctattttat attacagaac agatcgtccc ctcgggttga atgctgacga attgaatcaa
    12481 gaaacgccta ttgcaaccta tctatatcaa tatgggtttg cttctagtca agaaacaatc
    12541 caagttttgc agccatttga gatcgacaca aatggtcagc aagtggactt aggttctcga
    12601 atcacagggt atcagcaagg tgcagcaggt tcaagttttc ttgaatggca agaaggaaac
    12661 tggcgtattc gaatccgtgg gaataatata gaaggccaag atcccttact attagctaaa
    12721 gaaatcgtag cttatttgga agaaaacagt ctaccagcac ctgaacaatt tggtaaaatt
    12781 actgttgata tgggtgatac gacgaatcga gccgtagaag taagctggca agaaccgaaa
    12841 aatgcctata cgatcactca tcaagatcct atgtctgcgt tgaagatggc agtttctatg
    12901 aagaggttgt gaaatcagcg cgctgatctg agcccatcat ttaactccaa gtcacaggaa
    12961 gtaatcaaaa atagcacgcc gcatttttgc ataattttgg cttaatacct taaaagaaaa
    13021 ctagaattgc ctcttcacac atgctaaaat aaaacagaca aaaaagaaat ggggatataa
    13081 gttgactgaa tacttgaatg taggaaaaat cgtaaacaca caaggtatca aaggcgaagt
    13141 ccgtgttatc tcaacaacgg atttcccaga agaacgttac aaaaaaggaa cggtgctaac
    13201 actattccaa gacggaaaag cacctgtgga attaacagtc aaaagtcatc gcaaacataa
    13261 aaattttgac ttattgagtt ttgaaggaca tccttctatc aatgatgtgg aaaaatatcg
    13321 ggatggcata ttaaaagtgt caaaagacaa ctctgtagat ctagctgaaa atgaattcta
    13381 ttaccatgag atcatcggtc tgcatgtatt agaagatgga actgagttag gtaaagtaaa
    13441 agaaatcttg tcaccaggtg ccaatgatgt ttgggtcgtt caacgtccga aaaaagctga
    13501 tatattgctt ccatatatcg cttctgtcgt caaagaagtc gatttagaag ctggagtggt
    13561 ccgtgtagaa attccagaag gactgattga cgatgaagat tgatgtattg actttatttc
    13621 caagaatgtt tgaaggtcct atgggggaat ccatcatcgg taaggctgta gataaaggat
    13681 tattagatat caatatctct aacttccgcg attattcaga taacaaacat cagacagtag
    13741 atgattatcc atacggcggt ggagcaggta tgctgctcaa agtccagccc atctatgata
    13801 acatccaagc cattgaaaaa gctgcaccgg atgtcaaaaa aagagtaatt cttcttgacc
    13861 cagctggtaa acgattcgat cagaaaatgg cagaagaatt ttcacaagaa gaacacttag
    13921 tattcatttg tggtcattat gagggatatg atgaacgtat ccgcacatta gtgacagatg
    13981 aagtttcctt aggagattat gtccttactg ggggagaatt aggtgcgatg gtcatgatcg
    14041 atgcaacagt tcggcttttg ccagatgtgt tagggaatca gacttcagct caaacggatt
    14101 cttattcaac cggtttattg gaacatcccc aatatactcg cccggcagaa tataaaggga
    14161 tgaaagtacc agaagtattg acaaatggaa atcataaatt gattgaagaa tggcaattaa
    14221 aagaatcact aagaaggacc tatcaacgtc ggcctgatct tttggaaaca cttgaatgga
    14281 cacctcaaat gacgaaattt ttagaagaaa tcaagaaaga agaacaagaa aaaacagcag
    14341 atgaagccaa gtgacttttt ctaaaatctt ctttacagta ggttgataat atgttagtat
    14401 tttatggtga gtgcaaaagc acttaactat tacgatattc cgctgtgaga aaagctcata
    14461 agaatatttg gaataaggag aagaaaacca tgaatccatt aatcgaagaa ttaacaaaag
    14521 aacaattacg ttctgacatc ccagcgttcc gccctggtga cactgtgcgt gttcacgcaa
    14581 aagttgttga aggtactcgt gaacgtatcc agttatttga aggtgttgtt atcaaacgcc
    14641 gcggtgctgg aatcagcgaa acttatacag tacgtaaagt ttctaacgga gtgggcgttg
    14701 aacgtacatt cccattgcat acaccacgtg ttgcaaaaat cgaagtagtt cgctacggta
    14761 aagtacgtcg tgcaaaattg tactacctac gtgcattaca cggaaaagct gctcgtatca
    14821 aagaaatcag aagataaaca cggaaaactt ccttggaaat ctgaaatttg tgaaaagtcc
    14881 ttgtatatca agggcttttt cttttttctc tatcacagtt ttaagccatt tttggctgtt
    14941 ttggaccatt tttcaatcat attcccttaa aaattgtcct agattgtccg acattgacta
    15001 tcagtgtcgt caaaataggg caaaatttag tagtcagctt gacgacaaat ataatacgaa
    15061 aaataccaaa acatttaccg aatttagcaa cttttgaacc caagtttctc aaagggtcag
    15121 ctattagcaa aaaagacaaa acatgtactt ttctactaaa aagttgatgt gataggcttc
    15181 tatctaaata actattagga gtttttatcg tgaagcaaaa tgatggacgt atcatttgga
    15241 aaaatcaaag tgagttaaaa ctgattttaa caattaatga attcatcgaa aaacacggaa
    15301 ttacatctag ccgtcaatac cagaaaaagc tatcagaaaa tccaaattct gcaccaagta
    15361 tgtggttcat taacaaaaaa tatggatcat gggagaattt attgattagt ataggacgag
    15421 aaaatactgg gtatggaaaa tgggctagaa tgtcagaaca agaattattg gaaatagtag
    15481 aagcctttat taagtgcgag aagataacct ctcaacgaat gtacgaacaa aaatcagtag
    15541 ggaagaatat tccttcactt agtaccatta aaaagatgtt aggagatata cgtccacttt
    15601 ttaaagaaaa aaatgatgga tctcgattta ctgatttcga actgctgtta gaactaaaaa
    15661 atgaaataat ccgattaaaa ctacaggatg atttatcaat gacaaagttt cgaaaactag
    15721 ttcaatcccc aaaactacca tcagttgata caattatgaa aagaacgaac aaaaattggg
    15781 aggaattgat ggcagagatt ggatttgatt atcgaagaat caaaatttat aagcagagaa
    15841 acaacctatc caagacaaag aaaactaaat agtatcactc taaatcagac gttcaaaatt
    15901 aaaatttgga cgtctttttt attacccaaa aacgaaagga gatttatttt atgaaaaagc
    15961 caagatttaa gaattggcgt ttgctcgcaa cactgagtct attatgccaa acaattggtg
    16021 gatcgcttgg cccaacgatt gcctttgctg atgaaattac tcatccacaa acggtaactg
    16081 tggaattgga tttggctcac cagtatgctg tcgaaggtac atttagcgat ggtcgtccca
    16141 tgtcagaagt taccgttccg cactatgcag tttacaatgg tgtgaagcaa gatattttct
    16201 gtattgagcc aggggtgccg atttacaatg agttcactcc tggttatgag aaaaatccat
    16261 tgcctgatat gtcggagaaa gcgaaattag tttccgtttt atggaaggaa gctggtacgg
    16321 atgtggatac acatattgtg gcccagaaga tgatttggca agaagttaat ggctacacgc
    16381 ttcactcaat taaacgttct gatggtagtg cagtaaatat cgcagccatt gagtcaaaaa
    16441 tcaatcaagc cattgcggat tatcaaaaga aaccaagctt ccataactcc acagtgaaaa
    16501 ccgtgttagg tcaatcgact actgtgacag atacgaacgg cttgaattta tcggagtttg
    16561 atgaagttgt cgagaatatc gcaaatattg attatcgtgt gaacggcaat caactagtga
    16621 ttactccaaa tgccaattca aaagagagtg gtgaattaac cctaaagaag tcagctaata
    16681 caggaacacc ggtagcttat aaaatggctg gtcaacaaac tttgatggcg ggggcaattg
    16741 ataagcccaa tacctacaca atcaaaattg atgtggaaac tgagggttct ttgaagatta
    16801 aaaaagtcga taaagaaaca ggaaatgttg taccgggaac cgttttccat ttagactttg
    16861 gaaaaacatt acctgcaaaa gacgtgacca ccgataaaga aggcattgcg acattggatg
    16921 agattcctca tggcgcgaaa gtaaccatta ctgaaaaatc agtgccagct ccttatacga
    16981 ttgacactac accaatcacc gcaaccatta aatctggtga gactatttct gtgacttcaa
    17041 aaaatactcg cgaaaaaggt caaatcattt tgaataaaat gggggtggaa acaggaactg
    17101 atctttggaa cgacaaatac tcattagccg gaaatacgtt tgccattcgc aaagacagtc
    17161 caaccggtga aattgtccaa gaaatgacca cggatgaaaa aggtcatgcg gaaacaccaa
    17221 aagagattgc caatgcgttg gaattgggaa cctattatgt gaccgaaacc aaagctagta
    17281 atggctttgt gaataccttt aaaccagtaa aagtcgaatt gaactatgtc aatcaaaccg
    17341 tggctcttgt taccagtaac gtaaaagggc aaaaccaaga aatcactggt gaaaccactt
    17401 tgacaaaaga agacaaagat accggtaatg aaactcaagg taaagctgag tttaaaggag
    17461 ctgaatatac tctctttact gcaaaagatg gtcaagcggt caaatggagt gaggctttta
    17521 aaccagagtt agtgaaggga acgaaagctt ctgatgaaac ggtgactttg actttagatg
    17581 aaaagaatca agttgctgtt aaacacttag cgattaatga gtattactgg caagaaacca
    17641 aagcacctga aggatatacc ttggatgaaa caaagtaccc tgtttccatc aaaaaggtgg
    17701 atgataacga aaaaaatgcc gtgattaccc gagatgttac ggcaaaagaa caagtcattc
    17761 gctttggctt tgatttcttt aaatttgctg gatcagctgc tgggactgcc gaaactggct
    17821 tcaatgatct gacctttaaa gtatcgccat tggaaggaac cagtgagatt acagatgccg
    17881 aagatgaagc aattacagct tataacgagc aactaggttt tgatggctat ggcaagtttg
    17941 aaaatcttcc ttatggggat tatttacttg aagaagtaga ggctccagaa ggatttcaaa
    18001 aaattacgcc attagaaatc cgttctactt ttaaagaaaa taaagcggat tacactaaga
    18061 gtgaatacat ttttacgatt accgaaaaag gacaaaaaca accaattaaa acggtgaccg
    18121 ttccttacga gaaactgacg aataaagcat tttctgttag cttgaatcgt ttgatgctct
    18181 atgatttacc tgaagaagaa gatagcttaa cttctcttgg gacttggaaa gacggaggca
    18241 aagaattgac agaccttgat tctaccgagc tagttgataa attgagctat aacttgcatg
    18301 aaatcaaaga agactggtat gtggtagcgc aagccattga tgtggaagcg acaaaagctg
    18361 cccaagaaaa agatgaaaaa gccaaaccag tggtaattgc cgaaacaacc gcaacgttgg
    18421 cgaataaaga gaaaacagga acttggaaaa ttttgcataa attaaccgca gaacaagttt
    18481 tggataaaac catcgtctta ttcaactatg tgtatgaaaa caagaaaccc tatgaagcag
    18541 gtgatgatcc agtagcgaaa gatgctagct tgaacaatca agcccaaact gtcaattgta
    18601 cggtggaacg ccatgtttcc atccaaacaa aagcccacct agaagatggt tcgcaaacct
    18661 ttactcatgg ggatgtggtg gatatgttcg atgatgtgtc gattacccat gatgtactgg
    18721 atggctcaaa agaagctttt gaaacaattc tgtatgcatt acttccggat aatacgacca
    18781 aagaaatttg gaaatctggc aaaattgatt atgaagtgaa tgacaaagaa ttcactaaaa
    18841 ccgtacttgc ggaaaaagtg gacacaagta aatatccaga aggtacaagt tttaccttca
    18901 aagaaattaa ctatggcaaa gacggaaaca tcaatgggaa acacaatgag gatctaaaag
    18961 aaaaaactca aactttaaca cctaaaaaag ttccgacaac accaagtgca ccagaacaac
    19021 cggaaatacc aactgttcca agtgactctc aagaatctag tcctacagta aagacattcc
    19081 cacaaacagg ggagaaaaat tctaatgttc tgctgtttat tgggtttacc ttgatctttg
    19141 cgactgctgg gtattatttc tggaatcgcc gaaactaagg tgatgtgatg aaacaactaa
    19201 ataggaaaaa ccaacgtgcg cgaccgcctc ctaaaaaaag tggtcgcgct atttttgtat
    19261 ccaaaactaa aaatgaaaag aggaaaagaa gatggaattg aaatttgttg tgccagatat
    19321 ggccgaaacc tttggaaaga taaggtatgc cggcgaaggc gaagttttaa ctgaaggata
    19381 tgggcggaat actacagtaa ttggtcgtag ttatcatttg tattccagta agcaacgagc
    19441 cgatgatatt gaagtggtgg tagctgcgga agccggcgaa aaggattttg atcaagatca
    19501 accactaaaa gccgtgaatc cccatttggt tgccaaaggc tatgagattg agaatcgtgg
    19561 gtttaccgac tacgtgttgt atgtcgatga tttagtgaaa gcataggagg aaaagaagat
    19621 gagattaaca gaaggtattg ttgtagattc aggactaacg tttgggaaat tacgattttc
    19681 cgcattacgc cgagaagtac ggaagcaaaa tgaggatgga acggttagta acgaggtaaa
    19741 agaacggact tataatttga aatcctctgc gcaaggtcga atgatccaag ttagtatccc
    19801 agcaaatgta cccttacgcg agtttgccta tgacgcagag gtagagttgg tcaatccaat
    19861 catggatacg gtcgccaatt atgttttccg agaaggaact actgtcaatt ggttcattaa
    19921 ggccgatgat ttagtcttga aacgacaacc agatcaggga aattctacaa accaaaatga
    19981 aggaaagaaa taggtgaagc gtatggaaat taatgttgaa catattttag attgtctcga
    20041 tcaatatgga aaaggtgagc taacggagga acaactcact aaagcattaa cctatgatga
    20101 aaaaatgttt ctgattatgc atcaagggtt actggaagta ggtaacgatg ccgaagaaga
    20161 ttttgatgta ctgaattggt taggggaaga agagtccttc tttatggtta tcgaagtaaa
    20221 tgaaagtcta tgtcgagaag ccgaaaccgt attggaagaa attggtgtgg aaatgccgga
    20281 tgccattgaa gtttttttaa agcaactagt ggaaacgaaa caactcccta tagcagtaaa
    20341 tgactagcat aactgcttga aattggatca atgaaatcct atgaagcttt tttcgattgg
    20401 aggtggaaac cataaaaatg tacaaagggc atcgtatacg ggcaggagat cagcacttgg
    20461 tttatcactt tgttcttggc tggctactcg ctctgttcat cggttggatg agcgtctttt
    20521 attttcaaga gcttagacaa tttgatattt ctaagctatc actttctact atagaaatcg
    20581 ttcgttctat aaaagattta atctatttgc taggaagtct cgttctttca ggaagcacga
    20641 tgttgcttta tatacacttt tttcaggatc attggcgcag tttgtggcat cgacaaaagc
    20701 tagcccggat gattctagaa aatcattggt acgaagtaaa acaaactcag agtgaaggat
    20761 ttttcaaaga cctcaatagt agtcgaacca aagagacaat cagttacttc cccaaaatct
    20821 attaccgtat gaaggatggt ttactttcta ttcgcgttca aatttcactg ggaaaatatc
    20881 aagatcagct tttaaagctg gaaaagaagt tagaaagtgg tctatattgt gaactagtag
    20941 aaaaggaact caaagactcc tatgtggagt acactttact gtatgatata attgccaatc
    21001 gaattgggat agacgaagta gtggcagaaa gtggggcttt gcgattgatg aaaaatcaag
    21061 tatgggctta tgattcttta cctcatatgt taatcgctgg cggcacaggt ggtgggaaga
    21121 cttacttttt actcactatc atcgaggctt tattaaaatc tgatgccgag ctttttgttc
    21181 ttgatcccaa aaatgcggac ttagccgatt taggtacggt aatgcctcat gtctattccc
    21241 aaaaggagga aatttctgct tgtgtggaag atttctatga gcgcatgatg actcgtagca
    21301 aggcaatgaa agaaatgccc aactacaaaa caggagagaa ttatgcgttt cttggacttc
    21361 caccaaactt tttaatcttt gatgaatacg tggtttatat ggaaatgtta acgacgaagg
    21421 aaagtgcggt gattttgaat aagctcaaac aaatcgtgat gttaggtcgt caatctggtt
    21481 tctttctgat tctagcttgt caaagaccgg atgcgaaata tttaggagac gggattcgcg
    21541 atcaatttaa tttctgggtg gctttgggtc gtatgagtga actgggatat tccatgatgt
    21601 ttggcgaggt tgataaaaaa ttctttatga agcgtatcaa aggtcgaggc tatgtagata
    21661 cgggagggag tgtgattagt gagttttata cgccacttgt accaaaagga tatgatttct
    21721 taagggaaat tagcgacatt ggtggattaa acgttaatac ggaaggataa aataatagta
    21781 tgtagcctag gagtgtcaag aatcctgggc tttttttacg aggtgattta tgacattttt
    21841 agatttattc gctgggattg gtggcttttg cttaggtatg gaacaagcgg gtcaccagtg
    21901 tatcggcttt tgtgaaattg atgattttgc tcgccagagt tataaggcaa tccatgatac
    21961 aagtaaggag gtggaaatgc atgacatcac aagtgtatca gacgagttta ttcaatctct
    22021 cggaccagtg gatatccttt gcggtggatt tccgtgccaa gctttttcaa ttgcgggaaa
    22081 gcggcaagga ttttccgata ctcgaggtac tttattcttt gaaatcgctc ggttcgccgc
    22141 tattctccaa cctaagtttt tattccttga gaacgtccgg ggattactca atcacgaagg
    22201 aggggctacg ttcgagacga tcctccgaac gctggatgga ttggggtatg atgtggaatg
    22261 gcaagtgctt aactcaaagg cctacgttcc ccaaaaccgt gagcggatct tccttatcgg
    22321 acattctcga gacgcatgta ccgaacaagt atttcctatc attggatcgt ctccaacatc
    22381 tgatcaaaac atcagaaact tattaaatat caacccttcc aatcgaggaa tggggggaca
    22441 agtctatggg tcagatgacg tagcgcctac cttgaccggt gatgaaggaa tcaaaatcgc
    22501 attgccggta gatgatggaa tttctgtagc gggtatgtta ctgggaaatt ttgaacaagg
    22561 caatcgggtt tatgagataa ctggaacagc gcctactttg tcaacgaaac aaggcggaac
    22621 gaagatcatg cttcggaaaa acgaaacaga atatcaagag gtgaagccag ggaacagtgt
    22681 gaacctggct tttcctaatt ccacaagtcg tcgaggccgt ctgggaaaac aaagtgtgca
    22741 taccttatta acaggagacc aacaagcagt cgtcacggat cagtatcaaa ttcgaaagtt
    22801 aacacctagg gagtgctggc ggcttcaggg ctttccggac tgggcttttg atcgagcttc
    22861 tcaagtcaat tcagatagtc agttgtataa gcaggctgga aattctgtaa cagttccggt
    22921 catttttgat attgctagaa gattaaagga ggtaaaaaca gatgatttat gatgagttga
    22981 ttggggaatc tactgggtga ttggcaagat tcagtcagat ccggaattgg aagaagaact
    23041 gtaccggctc aattttgata ttcgcaaaaa cggggtgaaa gtccctgatg atccgtatgt
    23101 aattgatgag gaaacggatg ctcgaatgga gctgaatcaa gtcatcagtg aattggaacg
    23161 aattgcggac tttgctaaag aacctgatat ccgccaatac ttgtttgaga taaaagcaga
    23221 gttggaaatt gagggtatta ccgcggagta acggccaaat aaaccactga taggcactga
    23281 ccgcggggga tttgcgaagc agaaatcctc cgtggtgctg tgcctgttta tggacggcgt
    23341 tagccggcca tgatgtctca ccccccgtat ctaacagggg ggtacaaaaa cacaaaaaat
    23401 aagcaagcaa cgataaggaa tggctgtcct atcaaggata ataagcaatt tgtgtagatg
    23461 ttaactgatt tgaaaaagtt aacaccttaa atttggaggt gagaacttgg cacaaaggaa
    23521 tttagattat cggctattaa aagaccggcg taatgaatat ggcgtttcac aaaataaatt
    23581 agctacgact tgtggactta gtcgcccgta cttaaatcag atagaaaatg gtggcgtaac
    23641 cgcatcgaca aaaaccatga ggaaaatttt tgaccaactg gaaagtttca atcccgagtt
    23701 acctttaacg ttactgtttg actatgtaag gattcgcttt cccacaacgg atgcgaggaa
    23761 aatcattcaa gagattctcc atttgaaatt tgattatatg ctccacgaag attacgcctt
    23821 ttactcctat caagaacaat atgttatggg agatattgtg gtgatgttgt cacatgaaga
    23881 agataaaggc gtccttttag aattaaaggg tcgtggttgt cggcagtttg aaactttttt
    23941 actcgcccaa aagcgtagct ggtatgactt tttcgaagat tgtctaaaag ccggtggcgt
    24001 gatgaaacgc ttagacctgg caatcaatga tcgagttggc ctgttagata ttcctgattt
    24061 aacgaaaaaa tgtcagaagg aagaatgtat ctccttgttt cgtaccttca aaagctatcg
    24121 ttccggggaa ctgttgaaac ctgatgataa agatggtatg ggcaatactt tgtatattgg
    24181 cagtcttaag agtgaggtct atttctgttt gtacgaaaaa gactatgagc aatatatcaa
    24241 gttagggatt cctttagacc agaccgaaac gaaaaatcgt tttgaaatcc gactgaaaaa
    24301 tgatcgagct tatcatgcaa ttcaagattt gttaaaaggt cgcagtattg aaagtaccac
    24361 attttccatt attaaccggt acttgcgatt tgcggataag gtggaaggca aaaggcgaac
    24421 taactggccc ttgaatgaac aatgggggcg cttcattgga cggaatcaga aggaaattca
    24481 attaacttct gaaccgaagc cttataccat tgaacgaacg ttgaactggc ttggacgaca
    24541 agtcgcccct acgtggaaga tggccaagga gttggatcgg ttgaatcaga caacgtacat
    24601 tcaggatatg gtaaataata ctcgactatc agaccggcac aaaaagattt tggagcaaca
    24661 aagtatggca attgaaaatt tgattatatg aaaagaggaa tcgtgatgga aattgtgaaa
    24721 gatattttat tggtgtttgg tggcagtatg cttggtgtta ctgtgatgtg cttgatgcat
    24781 gcaagtgcag cggcggaccg agcaatggaa aagaaaggaa agtgatgaaa tgaatttcgg
    24841 tcaaaatttg tatcaatggt ttttaaccaa tgctcaatct ttagtcttac tagcgattgt
    24901 ggtcattggt ttgtttttag gatttaaacg cgagttttcc aaactgattg gcttcttggt
    24961 gattgctttg attgcggtag gtctggtctt taatgcttct ggtgtgaagg atgtcttact
    25021 caatttgttt aaccgaattg tcggtgcctg agggggaatc acaatggaac agatacgtgt
    25081 ttatattgcg aaccttggaa aatacaatga aggtgagttg gtgggggcat ggtttacccc
    25141 acccgtcgat tttgatgaag tgaaagaacg gattggatta aatgacgaat atgaagagta
    25201 cgcaattcat gattatgaac tgccttttga gattgatgag tatacaccaa ttgaggaaat
    25261 taatcggttg tgtggtttag cggaagagct taaaggaacg ccaattggtg aggtcgcttc
    25321 agagattcaa catgccttct tcaattcttt cgaggaaatg gtagagcatg tggatgatat
    25381 catctattat cccgattgta atgacatgag tgatgtagcg tattacttga ttgtagaagc
    25441 tggtgattta ggcgaagtac cagaacactt gaagacgtat attgattttg atgcgtgtgg
    25501 tcgagacttg gagattggcg ggaattattt ggttacgagt cgaggggttt ttgaactaat
    25561 gtaaatcatt tgttagaatt gaccagaaat ttctatcgta cttttacttt tctatttgat
    25621 atactgaaat agaaaatatt tgttgatagg ggtgttacta atggttggca ataagtggta
    25681 caaatgtgat cttcatattc attcaactgc gagtcagtgc tttcaggata aaaaggttac
    25741 tgctaaggaa tgggtagaag aatgtttaaa caaaggactc gattgtgttg cattaactga
    25801 tcacaataca ggggaaaata ttgatgaata taagaaagtg gctatcgaaa atggcttaga
    25861 tttttttcct ggagtggaat taacgtgtgg agaaaatgga actcatttac tagtcctatt
    25921 tgataaaagt gcatgtacaa atgatatctc tgatttctta accaagatgg gtataaaaag
    25981 agaggattgg gccagcgctg cagcttgctc aatgaaatca gttttagaag ttattgattt
    26041 tgctgagcac gagggcttgc tcgttattcc tgcacatata gatgagttta atggaatttc
    26101 ttcagcaaaa tttggaaatc taggaaagat atttgaatca gaaaatatat atgcagtaca
    26161 gacggttcaa aaagaatttt ttgaaaatcg ctcacaaatg attccctcat ctaagcgtga
    26221 cactatctat gatagtgtga atgccagata tgatggtaga gttggaaaag atactttgga
    26281 atcttggtat aaatcagttg ttgaggcaga aaaaaataat atgacatttc ttagcttttc
    26341 tgataaccca cactcgaaag gaaattcaaa acatggactt tggggaatag gcacaagata
    26401 ttcctatata aaaatgaagg acgaacctga cttgggatca cttcgcgatg ctttaatgct
    26461 aggcgaaact cgagttcatt ctgatttttc taatttctcc attaatgaaa atgaagtttt
    26521 attggaaaaa ttaagctttt ctgggaccac tcttagcaca aaagaagttg tagtcgaatt
    26581 cagcgataat ttaacttcaa ttattggagg aagaggaaca ggcaaatctt gtattacaag
    26641 attcttggtc tatgtccttg gaaaggaagc agaacttgat caattttctg aaatacaaag
    26701 tgattatcag aactttgcac aaattgaaca taatggctct ggaatatttt tgaaggatac
    26761 aattgtgaaa ctgaatattt tctataaggg gacaaaatat caaataataa gaacacagga
    26821 tagacattct atttatgaat ttacacaaga gaatggtctg gttgaaaaag aaacagaacg
    26881 gttgagaatg atttccgata aggtgagtat atactctcaa aaacaaattt atgaaatttc
    26941 aaaaaatcaa actagtatac tagaattact agatggatat aactctgatt tgatttcaga
    27001 gtataaaaat gagattgaaa catgtgtaaa cgaaataaga aaattaaatt gggatattgt
    27061 ttctgtgaaa aaagaaatac aagataaggc gaaggtagag cttgaaattg aagatttaaa
    27121 aaaacaagta gaaaagctat ctcataagag ttataaagat gtttatgatg agtattcaaa
    27181 agagacagat atttataggg aactgaaacg tgatgtggag gcacttaagg aaattcccaa
    27241 aaatctaact gatagtgttg acaaaattga ctttggcaat ggtataaaag ttacagacga
    27301 aattgatgaa caccgcggag aattgattaa gaatttagtg accaatcggg ctaagattca
    27361 aacaataatt aatgaaatgt cagatgaaat tgatagttat agagcagagc tgaataaatc
    27421 agattggaaa gttaactata atgaggtttc aaagaggtat caaagaggta tcaaaaactt
    27481 agtgaagagt tatctcaaga tgaattaaaa atgttacaaa accttgattc tttatatcaa
    27541 tctttatcaa aaactgaaga gcgattggaa gaaattattc aacaagaaat aaagcttaaa
    27601 gattaccaag ttgaggttga ctcagcaatg tcaagaatga ataaatcata tcaaaatttc
    27661 tattctgaga gaagtagttc ctcgcgcgaa attttttctg atattacagg aatagaggct
    27721 actattcaac caaataggga tttcaataat tatgttaaag agctcagagc ttgtattaat
    27781 aaggaggaca cttttgacag tgagtttgga tctcttattg ataagctgac aaaaaattcc
    27841 attactaatc aagatatata taatgacata cttgatataa gagttagtgg ggaaagtagt
    27901 attttttcag ataaaaaatt aatcaattct ataagaaaat tgaatgatgc acaagttctt
    27961 gaattacaaa cccttaagcc aaatgattta gtagttatcc gacttgaact aaatggaaaa
    28021 aaagttagtt tatcgaatgc tagtgctggt caaaagacat ctgcaattct ttctatgatt
    28081 ttggcgtatg gaaattcacc actcatattg gatcagcctg aagatgattt ggatagtcaa
    28141 ttaattaata acttaatcgt aagaagtatc attacaaaaa aggaaaacag acaaatttta
    28201 attgtaactc ataatgcaaa tatcccagtt aatggtgatt cagaatggtt gattagcatg
    28261 ggagattcaa aagaaatatc ggctgatcag tgcgggtcgg tagatgaacc caatatcaag
    28321 ccaagaatat gtactgtgat ggaaggtggc gaggatgctt ttacaaatag agcgaaacgc
    28381 tatggtttta aacaaattgt agaataacac tagagggtga gacatattat tatgtccgcc
    28441 ctttttagga ggaaaaatga aaaaaataaa aagctatacc agtatctggg cagttgaaaa
    28501 agtcatttac gcaatcaatg attttcagtt gccttttcct gtgactttta accaaatggc
    28561 ttggttcgtt ttatctttac tgtttgtcat cgtatttgcc catgtgcctc cactatctat
    28621 gatagaggag gtctttttaa aatacttagg cataccggtg gctgtcactt ggtttatgtc
    28681 gcaaaagacg tttgatggca agaaaccact gggattttta cgatccttta tcagctatca
    28741 cttgcgattt aaggtgactt ttgcaggaaa gaaagtcaaa gaacagaaga aacgatggga
    28801 tgaacccagt actcttgtaa ggagtgtgaa ctatgtatcc gattaagtat attgaaaata
    28861 atctcgtctt taaccaagaa ggcgagtgtt ttgcctacta tgaattagtg ccttacaatt
    28921 actccttttt gtcacccgaa cagaaatttc aagtgcatga taactttcgc caactaattg
    28981 cgcaaaatcg tgaaggcaag atccatgcgt tacaaattgc cacagaaagt agtattcgcg
    29041 ccacacaaga acgatcaaaa aaagaaatta ccggtagact caaagaagta gcgaaacaac
    29101 gaattgatat acagacagat gcattagtat ccatgattgg cgatagtcag attgattatc
    29161 gcttttttat tggctttaaa ctaattgcga cagatgaaga agtcaatcta aagagtctca
    29221 agaaatcttt cttttctggg cttcaagaat ttgtctatgg agtgaatcat catttgatgg
    29281 gcgattttgt ttccttatcc aatgaagaaa ttcgctgcta ttctaagctt gaaaaattaa
    29341 tggaaagcaa attggctcga agatttaaag tcaggcgagt cacaccgagt gacctgacgt
    29401 atttgattga acatatttat ggcgaaaaag ggataccgtt tgaagaatac gaatttcagc
    29461 taccaaagaa aaagctaaaa tcagaaacac tggtgaaacg ttatgactta ttacgtccaa
    29521 atcgttgttt aattgaagaa aaaccaaggt gcttacggat ggaacatgag aatcatgagt
    29581 cgtacgtagc gtatttaaca attaatacaa ttgtggggga gatggaattt ccttcctcag
    29641 aacttttcta ttaccagcaa caacaattta cattcccaat cgacacaagt atgaatgtag
    29701 agattgtgac gaataaaaag gctttagcta ccgttcgtaa taagaaaaaa gaactgaaag
    29761 atttagacaa tcatgcttac caatctgaca atgaaacgaa ttccaatgtc ttagatgctt
    29821 tggattccgt ggatgaattg gaaaccacct tggatcagtc aaaagaatct atgtacaaac
    29881 tgagttatgt ggttcgagtg agtgccgaat cagtggatga actaaagcga cgctgtgatg
    29941 aagtgctcga tttttatgat gataccaatg taaaactagt ccggcccttt ggcgatatga
    30001 tggggctaca tgaagaattc ttacccttaa gtaaacgata tatgaacgac tatattcagt
    30061 atgttacgtc tgattttttg gcggggcttg gttttggggc tactcagatg ctaggagaat
    30121 tagaagggat ttactttggc tacaatgtgg atacaggtcg taatgtttac ctgaaaccgg
    30181 cattggcttc acaaggagtc aagggttcag taaccaatgc gctggccgcc gctttcctgg
    30241 gttctcttgg tggaggtaaa tcctttagta acaatctctt agtctactat gctgttttgt
    30301 tcggtggtca agctgtgatt gtcgatccaa aagg
//
LOCUS       DAJSMK010000025        29981 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.025, whole genome shotgun sequence.
ACCESSION   DAJSMK010000025 DAJSMK010000000
VERSION     DAJSMK010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.025"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(82..2444)
                     /locus_tag="ON488_001158"
                     /pseudo
     CDS             complement(82..2444)
                     /locus_tag="ON488_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            2892..3065
                     /locus_tag="ON488_001159"
     CDS             2892..3065
                     /locus_tag="ON488_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3231363.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            complement(3222..3569)
                     /gene="rbfA"
                     /locus_tag="ON488_001160"
     CDS             complement(3222..3569)
                     /gene="rbfA"
                     /locus_tag="ON488_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HCR3231364.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3596..5902)
                     /gene="infB"
                     /locus_tag="ON488_001161"
     CDS             complement(3596..5902)
                     /gene="infB"
                     /locus_tag="ON488_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HCR3231365.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5915..6226)
                     /locus_tag="ON488_001162"
     CDS             complement(5915..6226)
                     /locus_tag="ON488_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HCR3231366.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6223..6516)
                     /locus_tag="ON488_001163"
     CDS             complement(6223..6516)
                     /locus_tag="ON488_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HCR3231367.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6538..7713)
                     /gene="nusA"
                     /locus_tag="ON488_001164"
     CDS             complement(6538..7713)
                     /gene="nusA"
                     /locus_tag="ON488_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HCR3231368.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7736..8209)
                     /gene="rimP"
                     /locus_tag="ON488_001165"
     CDS             complement(7736..8209)
                     /gene="rimP"
                     /locus_tag="ON488_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HCR3231369.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8354..12712)
                     /locus_tag="ON488_001166"
     CDS             complement(8354..12712)
                     /locus_tag="ON488_001166"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HCR3231370.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            complement(12924..14633)
                     /locus_tag="ON488_001167"
     CDS             complement(12924..14633)
                     /locus_tag="ON488_001167"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HCR3231371.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTNLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELVNTLPILLN
                     QGE"
     gene            complement(14701..15969)
                     /gene="rseP"
                     /locus_tag="ON488_001168"
     CDS             complement(14701..15969)
                     /gene="rseP"
                     /locus_tag="ON488_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HCR3231372.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAILLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPDKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16130..16930)
                     /locus_tag="ON488_001169"
     CDS             complement(16130..16930)
                     /locus_tag="ON488_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HCR3231373.1"
                     /translation="MKQRVVTAAVALVLFIPIIWIGGIAVELTAAILAVIGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16927..17739)
                     /locus_tag="ON488_001170"
     CDS             complement(16927..17739)
                     /locus_tag="ON488_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HCR3231374.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17934..18491)
                     /gene="frr"
                     /locus_tag="ON488_001171"
     CDS             complement(17934..18491)
                     /gene="frr"
                     /locus_tag="ON488_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HCR3231375.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18494..19216)
                     /locus_tag="ON488_001172"
     CDS             complement(18494..19216)
                     /locus_tag="ON488_001172"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HCR3231376.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19352..20233)
                     /locus_tag="ON488_001173"
     CDS             complement(19352..20233)
                     /locus_tag="ON488_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HCR3231377.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20332..21114)
                     /gene="rpsB"
                     /locus_tag="ON488_001174"
     CDS             complement(20332..21114)
                     /gene="rpsB"
                     /locus_tag="ON488_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HCR3231378.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21473..21952
                     /locus_tag="ON488_001175"
     CDS             21473..21952
                     /locus_tag="ON488_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HCR3231379.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22169..23260
                     /gene="phnW"
                     /locus_tag="ON488_001176"
     CDS             22169..23260
                     /gene="phnW"
                     /locus_tag="ON488_001176"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HCR3231380.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23253..23381
                     /locus_tag="ON488_001177"
     CDS             23253..23381
                     /locus_tag="ON488_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCR3231381.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIR"
     gene            23385..23930
                     /locus_tag="ON488_001178"
     CDS             23385..23930
                     /locus_tag="ON488_001178"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HCR3231382.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(24384..26075)
                     /locus_tag="ON488_001179"
     CDS             complement(24384..26075)
                     /locus_tag="ON488_001179"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HCR3231383.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26495..27442)
                     /gene="arcC"
                     /locus_tag="ON488_001180"
     CDS             complement(26495..27442)
                     /gene="arcC"
                     /locus_tag="ON488_001180"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HCR3231384.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27557..28576)
                     /gene="argF"
                     /locus_tag="ON488_001181"
     CDS             complement(27557..28576)
                     /gene="argF"
                     /locus_tag="ON488_001181"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HCR3231385.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28667..29896)
                     /gene="arcA"
                     /locus_tag="ON488_001182"
     CDS             complement(28667..29896)
                     /gene="arcA"
                     /locus_tag="ON488_001182"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HCR3231386.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         7981 a         6435 c         5360 g        10205 t
ORIGIN      
        1 ttttttccgt tttttttatt tattttttca gtttcttaat caatgtaaaa aattctattt
       61 tgcgggatcg attttatcat tttattggtc aagatttttc catttccaat ccaatacttc
      121 tggcagatca ataccatttt cacgaatata gttttgatgt tcttgtaatt tctgatccat
      181 ttttttcgca aaatcttctg cttgacttcc tttgattttt aaagctgcgt cttttgccaa
      241 atgataacga tcaagttcat ttactacacg catgtcaaat ggtgtcgtga tatctccatt
      301 ttctttgtag ccatgaatca ttaaatgatg gttatgacga tcaaagaaaa tcgtgcggac
      361 caatgtttca taaccgtgga aagcaaataa gatcggtttg tcttttgtaa aatattgatc
      421 aaattcttca tcgctcaacc cacgcggatc ttgacttgga tgacgtaatt tcaataaatc
      481 tacgacattg atgaaccgaa tttttagttt tgggaattct tccagcagca aagttacagc
      541 tgctaatgct tctaagttag attccgttcc tgcagcagca atgaccaatt caggttcctc
      601 ctcttttgct gtcgaagccc aatcaatgat tttcaagcct tcattcacta agacggctgc
      661 ttcttctgct gagtaaaatt gagcacgcgg atgtttggaa gagatgatca aattgatttt
      721 ttctgacgag cggaatgctt tatccatgac tgcgagcaat gtatttgcat ccgcaggcag
      781 atattcacgg atgaactccg ccttcttttc tgccaaatgt gtcaatattc ctggatcttg
      841 gtggctatat ccattgtgat cttgctggaa gactgttgag cttgcaatga gatttagcga
      901 aggataatca tttcgccaag aaaggtcatg tgatttccgc atccatttga agtgctgagt
      961 caacatagag tcaaccactc gcaagaatga ttcgtaactt gcaaaaaacc atgccgtcca
     1021 gtcagaacgt acccttctaa gaacccttca tcttggtgtt ccgataattg actgtcgatg
     1081 acgcgaccag atggcgaaag ccattcatca ttttctggtt cgattttttc catccattgg
     1141 cgatttgtcg ttttgaaaac ttgattcaat cggtttgatt ttgtttcatc tggtccaaat
     1201 atacggaaat tttctggatt tttctcaatg atctcgcgaa cgaatttacc aagttcggtc
     1261 atatcttctg ctttaacgga gcctggtttt tcaaattgca aagtatattt tttccaatct
     1321 ggcataataa gcggtcttgg atcgattcca ccattggtga taggattttt tgccattctt
     1381 tggtcaccag taggcgcgat ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat
     1441 aatttttctg gttcatagga tttcagccaa cggagtaaag catctgcatg atccatatgt
     1501 tcttgatcta caggaatcgg tacttggtgt gctcggaagg ttccttcaat tggttccccg
     1561 tcccattctt ttggaccggt ccatcctttt ggtgtgcgta cgatcaatac tggccatttt
     1621 ggcatcacga catctgttgc tgtcttcagg cgagcttctt tttggatgga tttaattttc
     1681 tcgattgctt gatccatttt ttcagccata acaggattta atttttctga atcatttcct
     1741 tcaataaaga aaggttccca gccaagtccg ttaaagtaat ttgctaattc tccatctgat
     1801 ttacgtgcca agatcgttgg gttggctatt tttgcaccat ttaaatgaag gatcggtaaa
     1861 acagctccat ctatcactgg attgataaag acatttgaga accagcttcc agctaaagga
     1921 ccggtttctg cttcaccatc accaatcacg acagcagaga ttacttcagg attgtctaat
     1981 acagctccga ctgcatgtga aagagagtat ccaagctctc cgccttcatg gatagaacct
     2041 ggtgtttctg gtgctgcatg agaagcaatg cctccaggaa atgaaaatcg tttgaataat
     2101 ttttgcattc ctgtctcatc ttccgttact tctggataga tctctgtgta acttccatct
     2161 aaataagcat tcgataccat gacttgtccg ccgtgtcctg gcccttcaat ataaaacatg
     2221 ttcaaatcat atttattgat gactcggttc aaatggacat aaataaaatt ttggccagga
     2281 atcgttcccc aatgaccgat tggatgtttt ttgacatctt cgggtttcag tgtacgtctc
     2341 agtaaggggt tatctttaag ataaagttgc ccaacagaaa gataattagc agcacgccac
     2401 caagccgtca ttttatcaaa gtattcttta ctagaataat ccatacataa cactcctttt
     2461 cattattact cttattctag cgcagatact cccaattgaa acctaataag cacttctgtt
     2521 catttgtttg gattttatat ctagccaaat gaacaggtat aaaaaaccac gaaatttttc
     2581 ctttcgctga cgttttttac attgatccaa aaaacttgtc gttatcacaa tggctgttcc
     2641 gcagttcatt tcgctcctca tcatgcataa tttgctgaat gacgctgggc cagttaacac
     2701 attgctggaa aactggggct ggatcgagca attcctttcc tgattgatcc gttttatgta
     2761 aaagtctctg ttatctttgt caatatgtga attggtatcc cagctactat gctaatttct
     2821 acagggatta tccaaaattt ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca
     2881 ataacttcaa cgtgattttt cttttaactg tcaacggacc gacaaactca aacttttatg
     2941 gtgcaggttc cactgatctt ctagttactt ggctatacct gactgtcact aaaatagatt
     3001 acaatctagc ttccgttatc ggtatcttga tctttatcta tatgcaaaaa tttatatact
     3061 actagaaaaa agaaagtcga attttttact tttctttttc tcttttttgg ttagctgaca
     3121 cgccgcaaga ctaaagtcat ggaactctta ggtaatacgt cttaatgaaa acaaaaaaat
     3181 cccgcaaccc ctgatttcac aggatttgcg ggagtttttg attagtcttt gttcaagtcg
     3241 cgaagcaatt catcgatatg gttgccatag acaactgatt catcaagttc aaagaacaat
     3301 tcaggtgtct tataaatact tagattgtgc cctaactctc gacgaatcaa tcctgatgct
     3361 ttattcaatc catcttgtgc tgttttctta tctgatgcta agtcagataa aatgctgtaa
     3421 tagatcgttg cttgctgtaa gtcccccgta actttcacat ctgtgatcgt tacgttctcc
     3481 acacgagggt cacggacctt tttgcgcaaa atatcattga cttcttttaa gatttcttga
     3541 ccgactcggc ggtcacggta gttagccata atgattggcc tccttttatc agtttttagt
     3601 catttttgac ttcttccatg ataaatcctt caattacgtc atctactttg atgtcattga
     3661 atttttcaat cattgcacca cattcataac ccattttgac ttctttcacg tcatctttga
     3721 atcgtttcag acttgcaagt tggccttcat agattacgat tccgtcacgg attacacgga
     3781 caccgctatc tctacgaata tatccttctg ttacataggc acctgcaatc gtaccaactt
     3841 tagaaacttt gaaggtttca cgaacgatca tttgaccggt gattttttct tcaaattcag
     3901 ggtctagcat ccctttcatc gcagtttcga tttcttcgat ggctttatag atgatacggt
     3961 gaagacgaat atcgacttct tcagtatcag cttgcacttt tgcctgcggt gtaggacgaa
     4021 cgttgaaacc gatgataata gcgttgctgg ctgctgctaa ggttacatca ctttcattga
     4081 ttgctccgac agctgaatgg acgattttta cacggacacc ttccacatca atcttcttca
     4141 atgatgcagc cagtgcttct gctgaacctt gtacatctgc tttgatgatt acgttaactt
     4201 ctttcaattc gccttctttc aggctttcaa ataagttatc caaagtcaca cggcttgtgg
     4261 cagcacggtt ttctaataat gcacgtttcg cgcgttcttc acccgctgca cgtgctgtct
     4321 tttcgtcttc gaagactacg aaacggtcac ctgcttgagg tacatcattc aagccagtga
     4381 tttctactgg cgttgcaggt cctgcttctt tatcgcgacg gccaagatcg tttgtcatta
     4441 cacggacacg tccgtaagta ttaccgacaa cgattgggtc accaacatga agtgttcctt
     4501 cttggacaag taaggttgac acaggacctt tacctttatc aagacgtgct tcgatcactg
     4561 ttccgattgc gcgttgtgtt ggatctgctt ttaaatcttc tacttctgcg actaacagga
     4621 tcatttccag caattcttcg atgttttggc cgaatttcgc tgagatctca acaaagatcg
     4681 tttctccacc ccatgcttca ggaattaact catactcact taattcttgc ataacatgtt
     4741 gagggtttgc acctggttta tcaattttat ttacagcgac gatgattgga acgcctgcag
     4801 ctttggcatg gttgattgct tcaactgttt gtggcatgac gccatcatct gcagcaacaa
     4861 ctaagatcgt gatatctgtg atacttgctc cacgtgcacg catacttgta aaggccgcat
     4921 gtcctggtgt atccaagaaa gtgattggtt taccatcaat atcgatctgg taggcaccga
     4981 tatgctgtgt gattccgccg gcttcgccgc ttgttacacg tgaatggcgt aatgtatcca
     5041 ataaagttgt tttcccatgg tctacgtgtc ccataatcgt tacgactggc ggacgtgaga
     5101 ctaatttatc tggatcgact tcttctgcct cgaagaattt atcgatatca gcaatgtcaa
     5161 cttggacttt ttcttgtggt tccatgccat agtccgtcgc taacagttca atcgtatctt
     5221 tatccagtgc ttggttttga ttgaccatga caccaagcat aaataatttt ttaatgattt
     5281 ctgctggctc acgatgaatt tttttcgcaa tatctgctac gttcatacct tcagtatact
     5341 ctaatacatc tggcaattca cggaatttgc gtggtggtac agctggttta gttgattgtt
     5401 gctgtttgcc ttttttacct tttttattat aacgattacg gttattatta ttaaatttgc
     5461 cgcgattgtt attgtttggt ttgttgttat tgttagtacg gttttgattg ccgccttggc
     5521 tcgttccttg acgattttgg ctgctggtat ttcccgtatt attttggttt gttgttggtt
     5581 tttttccttg attcacttga ccgctccctt gaccgcgatc ttgataactg cggttatttt
     5641 tatttttttg ttgattgttc gttgtttctt ttttacgttg atcgttcggc tgttgattgg
     5701 ctggttttct gcttgcttgt tgtgcagctt gttgtttcgt gcttgggttt ttgaacgctt
     5761 gttgcaattt cttctcatca ttgctagtaa tcgcacccat atggtttttc acatcgatgc
     5821 caagttgttg tgctttttcc acgacgtctt tactagattt tttgagttct tttgctaatt
     5881 catagattct tttgttgccc atgcaatcac cttcctaacc ttcaattagc tccttggtct
     5941 tcttcgcaaa tccggcatcc attattccga ataccttgcg aggttttccg atcatctgcg
     6001 tgatttctgc ttcagaaaat agctcaaagc aaggaacttc ataatatgaa ctcttatctt
     6061 ttatcttttt tcttgtattc tcgcttgcat cggttgccac aaacaccaat tttgcttttt
     6121 gtttgcggat ttcagcaatg gtcagttctt cacccgtgat tagttttccc gcgcgcatcg
     6181 ctagaccgat gagattcatg gctttttgcc gattaactgt attcattttc caaataactc
     6241 tttacgtgct ttttggtgag tgacatagtc aagaagttct tgataaaact catctgttaa
     6301 tgttgtttcg agtactcgat cgagaatttt tttatcccaa gcttgttgta cttcttccgg
     6361 ctcaagtgag acatacgctc ctcgtccagg catttttcca gttggatcga tcgatacttc
     6421 cccttctttt gaacgggtga ttcggaccat ctctttttta ggtttcattt cacctgaaac
     6481 cacggatttg cgtaaaggaa ttttcctttg tttcatctct ttgcctcctt actaaagtta
     6541 agcttctggt ttttcttcga ccgtttcatt gttgaatgca attgtttcat attcatcgtc
     6601 tgttaaatct gactgaacga ttgcttcatc atgcagttct tctgtttctt tttgttgttc
     6661 ttgattttca taaaattccg tcatgtcaga ttctgatttg atatcgattt tatggttagt
     6721 caatttagca gctaaacgtg cgttttgtcc gcgtttaccg attgctagcg ataattggta
     6781 gtctggaacg acaactgtgc aggcctttgg atttgtctca tcgaagatca catccatgac
     6841 ttgtgcagga ttcaatgcat ttgcaatgaa tacagctgga tcttcattcc attcgacgat
     6901 atccatgttt tcgcctttta attcattgac gattgcttga actcgttgtc cctttggccc
     6961 gacacatgta ccgactgcat cgatatttgg atcatttgag cgaactgcca cttttgaacg
     7021 atcgccagct tcacgggcga tgctgacaat ttcaacgatt ccatcataga cttctggtac
     7081 ttcttgctca aataagcggc gcaataggtc tggatggctg cggctaacaa atacttgcgg
     7141 acctttagac gtattttcta ctcgggaaac ataaactttg attcgatcat gtggttgata
     7201 aaattcattt ggcatttgat cttgtttaga aagaactgcc tcaattttac caagattgac
     7261 ataaatataa cgtttatcct ggcgttcgac gattccttgc atgatgtctt tttcataagc
     7321 actgaattcg ttataaataa tcgttctttc tgcttcacgt acacgctgta aaataacttg
     7381 tttagccgtt tgcgcagcga tccgcccaaa atcttttggt gttacttcaa aacggatcgt
     7441 atcaccgatc tcatatgctg gattgattaa aagtgcatct ttcaatgaga cttccaactg
     7501 tgaatccatc acttcttccg ttacttcttt taccgcatag acatggatct ttcctttttt
     7561 ctgatcaaat tccacttcga cgttttgtgc ttggccatag tgacgtttgt atgcagaaac
     7621 caatgctgct tctaaagcat cgatcacgat ttcttttgag atcccttttt cagcttctaa
     7681 agcgtctaac gcatttaaca tttctttact cattttttct gattcctctc cgtgattaaa
     7741 attggatagc taagcgagct tttgcaatat tttttcggtc aaaagtcaat tctttttctc
     7801 gtgtttttat gcgtattttc aatgtaagct gttcagcatc aaatgattga agaaatcctt
     7861 catattgttt ttcgccatct actggttggt ataaggagac atggacataa tcaccaagtg
     7921 ccttttcata gtcgctttct tttttcaatg gccgctctgc tcccggggag gatacctcca
     7981 ggaaataagc ttgaggaatc ggatctggat ctgctgcatc aagtttttca ctcagtttct
     8041 cactgacaaa ggcgcattct tcgatatcga taccgccttc tttgtcaata aatactcgta
     8101 agaaccagct ttttccttct tttacaaatt cgacttcgac aagttcaaaa ttttgttcat
     8161 ctaaaatcgg tgtcaccatt tctgtgactg tttcaacgac gctactcaaa agtttcgcct
     8221 ccttaaaaaa ttaagtgcgt aattccatta aaaagagtga gcgaaaaatc cgctcactca
     8281 cagttagtat cattacctat aagaactata ccatactctg cttaaaatta caagcagaca
     8341 ggaaaacaga tgcttatagc atatcgaata acgataattg attttcatct ggtagatctt
     8401 tcaatacgcc attgtcgttc atatattcga tcaatgtttt tgaaacttta ccgcgggtgg
     8461 caagatcttc tttggataaa aatggaccgt cttttcttgc ttcaacgatt tgttttgcca
     8521 cgttggttcc caaacttggg acagctctaa atggtgcgat caacgtatca ccttcaataa
     8581 caaagttaac ggcatccgat ttatacaaat caatcattcc aaatttgaat cctcgttcca
     8641 gcatttcatt ggctaactcc agcactgtca gttgattctt ttcttttacg gaagcatcta
     8701 atcctttgtc cgtgatttct ttcattgctt gtttcacagc atcttttcct ttgcacatgg
     8761 agactagatc aaagtcgtct gcacgtacag aaaagtatgc acagtaatac aaaataggga
     8821 aataaacctt gaaataagcg acacgaagag ccatcaatac gtaagctgca gcatgggctt
     8881 tcggaaacat atatttgatt tttgaacaag aatcgatata ccagtcgggc acattatttt
     8941 ctttcatcgc cgatagatag gtttctcgca attcatcagg gatcttgttc cattgtcctt
     9001 tacgaacagt ttccatgatt ttaaatgcca tcccgctatc taatccagca tggatcaaat
     9061 aaaccataat atcatcacga cagccgatta cttccgccag tgtcgcatct cctcgtcgaa
     9121 tcaattcttc cgcatttcct aaccatacgt ctgtaccatg agatagtccg gaaatttgca
     9181 gtagttctgc aaaagttgta ggatgcgttt cttctagcat ccctcgaaca aaacgagtgc
     9241 cgaattctgg aatacctaat gtccctgttt tggaataaat ttgttcctga cttactccaa
     9301 gtacttcagg accggcaaat atccgcatca cttccgggtc atccgtaggg atcgtttgtg
     9361 gatcgatccc tgataaatct tgaagcatcc gaataacagt tgggtcatca tgccctagaa
     9421 tatctaattt caatacatta tcgtgaatcg agtgaaaatc aaaatgagtc gttttccatt
     9481 ccgaattttg atcgtctgct ggatattgga tcggcgtaaa atcatagaca tccatataat
     9541 cgggaataac gatgatcccc cctggatgct ggccggttgt ccgtttgact ccagtagcgc
     9601 cttttgctaa tctgtcgact tctgcacttc gaaactgcag attattgtcc ctttcgtatc
     9661 cttttacata gccatatgct gttttgtcgg cgactgtacc aatcgttccg gcacggtaaa
     9721 catagtcttc gccaaacaat actttcgtat agttatgggc ttctgcttga taatcacctg
     9781 agaagttcaa atcaatatcg ggcactttgt ctccatggaa tcctaaaaat gtctcaaatg
     9841 gaatatcatg accgtctttg tttaagcgtg caccacattt tggacattgt ttttctggca
     9901 tgtcaaatcc agaaccatac gtaccatctt caaaaaactc ggaatattgg cactctggac
     9961 aataataatg aggggctaac ggattaactt cagtgattcc tgtcatcgtc gcaacaaagc
    10021 tagagccaac agagccacgt gaacctacta gatagccatc ttcattactt ttatgcacta
    10081 gtttttgggc gatcagataa ataaccgaga agccattacc attaatagaa ttcaactctt
    10141 tttttaatcg tttttgaatg atctcaggta acggatctcc gtacatttgt tttgcttttg
    10201 tgtaactcaa ttctgatatt tcatcttctg aacctggaat cttcggtgta taaagttcat
    10261 ctttgactgg aatcacttct tcgcagatat ctgcgatttt attcgtattt tctactacga
    10321 tctctttcgc tgtttcttcc cctaaaaagt gaaatgcagt tagcatctca tcggttgttc
    10381 ggaaatggac atccggcaaa ctatgacgat tcaacggatt cgctccgccc atagaattga
    10441 tcaaaatttt tcggtaaatg gcatcttctt cgttcagata atgtacatta cctgttgcaa
    10501 caacgatttt atccaaactt tttccgattt ctaccaaatt ttggataatt tcttccaaat
    10561 catgttcatt ttttaccaat tcttgctcga tcaaaggcgc atagaccgct tttggcataa
    10621 cttcaatata atcgtagaat tttgctcggt ttcttgcctc ttctacccct ttttgcatca
    10681 tggcttcgaa tatttctccc ttatcacaag ctgagccgat caatagattt tcacgcatct
    10741 ttttcaattg ggagcgtggt attcgtggga cgcgttcgaa gtattcgaca ttcgacattg
    10801 aaatcagttt gaacaaatct ttcagtcctg cctgattttt tgctaaaatc gttacatgga
    10861 aaggtcgagc ccttttgtaa gaatctcctt ctccgatatg ctcatttagc tgatcatgat
    10921 aaagcatgtt atgattgtcc attgcctctt tcacaaagat ccatgctaag tgaccagttg
    10981 cttcagcatc atagattgct cggtgatgct gttccaagct gacaccaaat tttttagata
    11041 acacacctaa tccgaaacgt ttgaattgag gatacagata tctagctaat tccaacgtat
    11101 caatgactgg attggccgct tcaggaatac cataccttgc gtagctagta ttcaagaacc
    11161 ccatatcaaa agccgcgttg tgggctacca aaattgtatc ttttgaaaat tcaaggaaca
    11221 tccgcaatac ttcttcttcc gactttgatc ctcgaaccat tccatccgtg ataccagtca
    11281 gatctaccgt tgttcgtgac aaaggatgtc ctggatcgat aaattcatca aagctttcga
    11341 tcacatttcc tttatacatt ttgactgcgg ctagctcgat gatcgtgtca tatactgcag
    11401 acaatcctgt cgtttccacg tcaaatacga catatgtggc ttcactcaat gcttcatgtg
    11461 catcattata agcaattggg acaccatcat ctacgacatt cgcttccacg ccgtataaga
    11521 ttttcacacc tgcttttttt ccagcactat gtgcttccgg aaaggcttgc gcaccaccgt
    11581 ggtctgtaat ggcgatagct cggtgtcccc atttccctgc ttgtgccaca agatcagaga
    11641 tgctgtttgt tgcatccatc gtactcatat tgctatgaac atgaagctct actcgttttt
    11701 ccccttcagg agcataatct ttgcgaggtg tatgtttgac ttctatgata tcttgcgcat
    11761 tcatgaccaa atcacggaca aacgtatctt cttgaatact tcctcgtacc tttaaccagc
    11821 taccgacact gatcgcatca aatacttgtt catctttttc gccgttcgag aattttttga
    11881 cgataaatga tgaagtataa tctgtgattt tcaaagtcaa gatcttgcgt tttgaacgta
    11941 gttctctgac ttctttgtcg aatacgtacc cctcaagtgt gactcttcgt tcttcttcaa
    12001 cgatactgat cattggtgtc gttggttcat cggctggaat atttcgtcct agctggatgt
    12061 ggatgggtcc ttcaagagct ggcgattgct cttttctttc ctttttcttt tgttcgtgga
    12121 caactagact ttcagctgct tgcttcataa aggcttctgc ctgttcttgt ttgcgttctt
    12181 caaaaagttt caatactcgt tccgcttgct gctcatccac ttctggttcg atacgaaatt
    12241 ttgggaatcc gtaactgacg aacaactctt ctactaatgg caagtattgt tgcttcaaat
    12301 aagaaatagc tcctgtactg tcgattggca agatgacttt acgatctttt atcacaggta
    12361 cctgcgtttt caatacttgc tgtgctagtg gtgtatcgca ttgctgattt tccaaagctt
    12421 gggcccagta atcttgcaag agctgttcat cgaatgtctg gtcatctgct aagatattca
    12481 gtttgacttg tgcaatatct ttaaaagcga tagtcagatg ctgagtcaat gaccgatata
    12541 gcataatagg caaaattttg gaaaaatgca gcgtaaattc ccataaacgc gatttacgat
    12601 ggaccactac actatccatt tcaccagcag taagcagtgg atgatttttt tctgcttcct
    12661 ctagttggat ttgttccaac agtttttcaa ataaatctcg tttttctgac aaagatatac
    12721 gccctttctg atgagaaaca atgcaattga tcgcatctta tcctcttctt tttcagtacc
    12781 ttttagtata ctcgtttttt ctgagtttta cattaaaaaa ttggaactgc gattcaaatc
    12841 gcagttccaa ttttaaaagc gaatcatcag attgtcaaaa acagctgatt cagctatttt
    12901 tattttctgt gttttaacgc ttattattcg ccttggttca agaggattgg taaagtattc
    12961 accaattctt ctttacgtac ttcaaccatt tcgccagttt tcttgatttt cacttctacg
    13021 attccatcca ctgctttttt accgacagtg attctgattg gacagccaat caaatcagaa
    13081 tccgcgaatt tcactcctgc gcgttcattt ctgtcatcaa ccagtacttc atagccagct
    13141 tttgtcatcg cttcttctag ttcattcgtc aggtttgttt ggtattcgtc ttttagattc
    13201 atttggacga tatgcaaatc aaatggcgca attccttttg gccagttgat tccttgttca
    13261 tctgaatgtt gttccacgat tgctgataat aaacgactta caccgatacc ataacagccc
    13321 ataatcacaa atttttctcg tccattttcg tctagtacag ttgctcccat agattcactg
    13381 taacgagtgc cgattttgaa gatatgtccg atttcgattc ctcgagtaaa ggcaagaaca
    13441 ccattgttgt ctggtgaagg atctccttct tgtacaaaac gaagatcttc ataagaaagt
    13501 acagtgaaat cgcgttctgg attcacattt ttatagtgga atcctgtttc gttcgctcca
    13561 gtaatggcat tcgctaaatc ttggacataa cggtctgcat atacttttac gtcatctgaa
    13621 acaccgactg gtccgacaga accaaactca gcacctagat atttttgtgc ttcttcttct
    13681 gttgcttctt ctaaaaagtc agcagataaa aagtttttca gttttacgtc attgacttca
    13741 tggtctccgc gtaccaaaac aaggacaggt tgttcatccg caatgaacaa tacagacttg
    13801 atgatttttt gaggttcaac agaaaagaaa tctgctactt cgtcaattga ttttacgtta
    13861 ggtgtagcta ctttctccaa ttcaagctgt gtttcatgcg atttttttga tacatagtag
    13921 cttgtagcca tctccaagtt tgcagcataa tcactttcag tcgaataaca gatcgtatcc
    13981 tccccgattt ctgagatcgc catgaattct tttgagtctt tcccgcccat tgcgccaccg
    14041 tctccgataa tcgagcgaaa ttctaagcca caacgcttga atacttcggt gtaggctttt
    14101 tcgtaatctt tatatgtctc gtccaaactt tcttccgttg catggaaaga atacgcatct
    14161 ttcatgataa actctcttcc gcgaagcaaa ccgaagcgag gtcgtttttc gtcacgatat
    14221 ttaggttgga tttgataaag atttaaaggt aatttcttat atgaattgat ttcattacgc
    14281 atcaaatcag taaaagtttc ttcgtgagtt ggtccaagga tcatttttcg atcattgcgg
    14341 tctttgaaac gatacaagtt tggtccatat gtttcgtaac gcccggattc ttcccaaagt
    14401 tctgctggca agatggcagg catcagcatt tctaccgctc cgattttttc aaattcttcc
    14461 cgcataatgc gtttcagttt ttccaataca cgatttgcta atggcagata tgaataaata
    14521 cccgctgata cttggcggat atatccagct cttagcaaga tttgatggct taatacttct
    14581 gcatcatttg gaacttcgcg taatgttgga atcaacattt ttgattgtct cattctatat
    14641 actcctttat ttcctcaaaa tagttatcgt ttgttattat accctatttg tcaacttttt
    14701 ctagaaaaag aatcgttgaa tatcgttcca tgtaactagc accatcaaca acattaaaaa
    14761 tccaaagcca gctaatgtca atattccttc tttttcttga cttaatggtt tcccgcgaat
    14821 cccttcaaaa atattcaaga ctaatttccc gccatctaag gcaggaatcg gaagcagatt
    14881 gacgattccg agattcattg aaagaagcgc catcaaacta ataacagttg ttacaccttg
    14941 atttgctgct tctgaagaca attggtacat catgacaggt ccgcctaatt tatctaaact
    15001 gaaacctgta aatagtgatc ctaaggcttt gaaaatttcc aatgaaccgc tgaaagcttg
    15061 acgcgtccct ccaatgatct tatccataaa acctgtattc attggggctt ttataccaag
    15121 ttggccaact ttttcgccat ttgactctac agatttcggt gtcacgtcga cagattgcac
    15181 ctgaccttct cgttcgatct taaagtctaa tgttttatcc ggatttttcg taatgactgt
    15241 tgtcagatca ttccatgaat ggatttcttt tccgtccaca ctgactacct catcattttc
    15301 ttttaagcct gcttctgccg cagctccatt aggcatgatc tctcctacgc gattagtgtt
    15361 cgtcacttga acaccacctt gcataaatgc cagaatgatg aataacagga ttgccaaaat
    15421 aaagttattc atgggtccag caaagttggt cagcatacgc tgccacaatt tagccgattg
    15481 gaactgtacg tcttttggcg caattctgat ttctgttccg tcgttttcaa taatcgtcgc
    15541 atcgtgatca acagggtagg ttactacttc tgtttcgtct ccattcacat aaccagtgat
    15601 agtcagctca tcttctaaat cataacggct caattccatc gggatagcat ttgtcaattg
    15661 gattttctta cttaaattta tcttctctac gatgccgtca gaatttagta aaagagaaag
    15721 aggcattcct ggtgccattt ctgtttcatc atccccattg cctgccattc gaacataacc
    15781 gccaataggt aataggcgaa gcgtatatgt tgtcccgtct tttgcttgat gcccataaat
    15841 tttcggaccc ataccgatag caaattcgcg aacgaggatt cctgatcgtt tcgcaaagaa
    15901 gaaatgacca aactcatgaa caatcactaa tataccaaaa acgatgataa atgtcagaat
    15961 cgttttcata gcttttttct cctttacttg ttttttgtgt tttttataaa acaacgataa
    16021 aacactataa ttttaccata gtataccaaa gacaccaata gtatcaatat aatgaaaaat
    16081 aaaaacctgc gtcttttatg aaattcacaa agaaacgcag gtatacttac taaataatgc
    16141 caaataaatg catgatagga aatacaaaca gcaaactgtc gaaacggtct aagattccac
    16201 catggcctgg taagatattt cccgagtctt tcacatcata atgacgtttg attgcagatt
    16261 cgaccaaatc accaaattgt ccgactgctg aaaaaataat cgtcatcaga agcatgacaa
    16321 acataccatg attaaatagt tcttttgctg ggtatagcaa taaataaaga aatgcgacta
    16381 caacagcact accaatacca ccgagcgcac cttcaatcgt tttgttgggc gaaatatcag
    16441 gacttaactt atgctgacca taacgtcgac caaccatata tgctccgata tcagttgccc
    16501 aaacaataaa tagaccaaat atcaaaacag ccaagctttc tgttcgtgca ttgacaaaat
    16561 tctggaaacc tattcccaca tacaagctga caagcacagg aaaacctgct tcatcaatcg
    16621 tatacgtatt tttagaaata actgatgttc ctaaaagaat cataactata agataaaata
    16681 acataaatgt acttacattc tctggaagaa agaaaaacca tctttctttt ggcaaaacaa
    16741 gtaacactgc accaacggcg gataaaactc cttcaaaact taagagtgtc aatcctttca
    16801 tccgaaacag ctcgtaaact cctattactg ctaagattgc tgctgtaagc tcaaccgcta
    16861 tgcctccgat ccatataatc ggaataaaca agactagcgc cacggctgct gtgaccacac
    16921 gttgtttcat gactgatccc ctttctcatc ttctgttttt tttacaccgc cgaatcgacg
    16981 gtctcgattt tgataagagg cgattgcttc ttcaagatgc gcaccatcaa aatcaggcca
    17041 aagcgctttt gtaaaataca gctcactata tgcgatctgc cataacagaa aattactaat
    17101 tcgctcttct ccacttgtac ggatcatcag ctcaggatct tgtaactctt taggcaagaa
    17161 acctgtcatt aaatgcttag caatcaattc atcatcgatt tcttctgcgt gtatttctcc
    17221 ttttgctact tcttcggcaa tttcttggac agcagtcacg atctctgctc tgcttccata
    17281 attcaaagca aaattcaata ccattccagt attgtttttt gtttgctcaa ttgcacgtct
    17341 tacagcatct tgcgtatgtt ctggcaatac gttttcataa cccatgacat gaactttgac
    17401 attttcttta atcaattctg gtacgaacgt atcaaagaag tcgacaggta gttgcatgag
    17461 aaaacttact tcatcttttg gtcgcttcca gttttcagtc gaaaaggcat aaagcgtcaa
    17521 cactttcact ccaagccttg atgctttttt tgtgactttc tttactgttt ccatgccttc
    17581 tttatggcca gcaactcgtg gcaaacgacg gttttgcgcc caacgaccat tgccgtccat
    17641 gatgatggca atgtgctgag gaattggtcc atcggtatta aattgaaatt cgcttttttc
    17701 ttgaatatat ttgttttttt gcggaaaaaa acgtaacatt ctttttcctc ctatacttaa
    17761 aagattccca ctatcttaag tattatagca atatctaact gtttttccta tgaaatcatt
    17821 gtttttttat ttaaaaactg aataattttt tcttttttta atttttaaat aaaagaaata
    17881 taaataaaaa cagaggaagc ggaatgatcc gcccctctgt ttttatgatt ttattaaact
    17941 tccaataatt ctttttcttt atcagcagcg atcttatcta cttctttgat gctgttatct
    18001 gtcaatgttt gtacgtcttt ttctaatccg cgcaaatcat cttcggtaat atcaccattt
    18061 ttttgttgtt ttttatattc atcgatcgca tcacgacgga tgttacgaat cgcgattttt
    18121 gcattttctg cttctttttt aacatcttta gctaattctt ttctgcgttc ttctgtcagt
    18181 tgcgggataa ctaagcgaat gacatttcca tcattggttg gactgattcc gatatcactt
    18241 gccataatag ctttttcaac atcttgaaga atgctcttgt caaaaggtgt gatcattaaa
    18301 acacgtgctt ctggaatttg gattgatgcc atttggttca atggtgttgg cgcaccgtag
    18361 tagttcacag taatacggtc caaaaggcta gcgttcgcac ggcctgcgcg gatttgccca
    18421 agttcacgtt gaagattttg tgctgctttt ttcatttttt cttttgcttc tgtcataatt
    18481 gcatctgcca tttttatttc ccccttacag ttgttccgat attttcgcct aagattgcac
    18541 ggcgaatatt tccgtgttca tttaaattga agacaagcag tggaatatca ttatccatgc
    18601 ttagtgaact tgcagttgaa tccatgactt gtaatccttt ggcaataact tccagatgag
    18661 tcagttcttc aaattttact gcatttgcat ctactttcgg atcagcagaa taaacaccgt
    18721 ctacattgtt tttagccatc aggataacat ctgcgccgat ttctgccgcg cgtaatgctg
    18781 ctgttgtgtc tgtcgagaag tacgggttgc cggtaccgcc tgcaaagata acgatccgtc
    18841 ctttttctaa atgacgttct gctttacggc gaatatatgg ctctgcgatt tgacgcattt
    18901 caatcgaagt ttgcacgcgt gtcggtacac ccacgttttc caacgtatcc tgtaaagcta
    18961 aggcattcat aactgtagct aacataccca tgtaatcagc ttgagcacgt tccatgccca
    19021 tttgtgctcc gatttgtccg cgccagatat ttccgccgcc cacaacgatt gccatttcaa
    19081 cgcccagctc gtgaacttct ttgatttctt ggatgatttc tttgattact ggtggtttga
    19141 ttccaaatcc tgcgtcccca gctaaagctt ctccactcaa ttttaagact acacgctgat
    19201 atttcggtgt gaccatgttc attcctccaa tattttctat tgccatttta ccatacttag
    19261 atgatttcga cactctaaga ctggtttttc ttgttttgct taaaaaaagg gagcgcacaa
    19321 accgtgcgtt cccgtctgtt attcaacaga attatttttt cacttggctc ataacttctt
    19381 ctacaaagtt atcttcgcgt ttttcgatac cttcgccaac ttcgaaacgt acgaatgttt
    19441 taacagttgc gccttttgat gcaacgtatt tttcaacagt catatcagga tctttaacga
    19501 atggttggtc caccaaagcg atttctgctt tgaatttctt caagcgtcct tctaccattt
    19561 tttcaacgat attcgctggt ttgccttcgt tcaatgcttg ttctgtaaga acagtttttt
    19621 catgttctaa ttcagcttct ggaatttgtg attcgtttac ataacgagga ttgatagctg
    19681 ctacgtgcat agctacgtct cttgcaactg tttcgtcagt tgttccatct agaacagtca
    19741 atacggcaat acgtccgccc atatgcaagt atccaccaaa tgcagcattg tcgtcttttt
    19801 ctacaacttc aaagcgacgg aagctgattt tttctccgat aacttgagtt gcttcgatca
    19861 agtcagattc aattgtacct ttatctgttt tgattttcat tgcagcttcc atgtctgctg
    19921 gtttgttttc agcaacaagt tctgcaattt cttttactaa atcttggaac atttcgtttt
    19981 tagaaacaaa gtctgtttct gagtttactt caacgattgc tgcagtgtta cctttcacag
    20041 caactgaagc caatccttca gctgcaatgc ggtcattttt cttcgcagcc tttgccattc
    20101 ctttttcacg taaaagatca actgcttttt ccatgtcgcc ttctacttca actaatgctt
    20161 ttttcgcatc catcattcct acgccagtca tttcgcgtag ttcttttacc attttagctg
    20221 taacgtctgc catgtttaac tcctcctgtg tgtttttctt tttaaaaaaa gctgcttcaa
    20281 aggagagtga ggcttgtcgc ccagcctttg aaacagctcc atcattcaaa attattctgc
    20341 tgaagaattg tcgccttcaa caacatctac gatttcttcg attgatgttg ctgtgttttc
    20401 ttctgtgaaa tcttcttcaa ctacttgatc ttcaccttgg tttccttcga tgaaagcatc
    20461 agccattttt gaagtaatca atttaacggc acgaattgca tcgtcgtttg aagggattac
    20521 tacgtcgatt tcatctggat cgcagtttgt atcaaccata gctacgattg ggatatttaa
    20581 tttgtgtgct tcttgaacag caatacgttc tttacgtggg tcaacgatgt acattacatc
    20641 tgggattctt ggcatatcag cgataccgcc taagaatttt tcaagacgtt cacgttcttt
    20701 gttcaaacca gcaacttctt ttttaggtag aacttcaaaa gttccatctt cttccattgc
    20761 attgatttgt ttcaaacggc tgatacgttt ttggatagta tcccagtttg tcaatgttcc
    20821 gcctaaccaa cgatggttaa cgaagtattg tcctgcacga gttgcttctt ctttgattgc
    20881 ttcttgtgct tgtttttttg tacctacgaa taatgctacg ccgccttctt cagcaacgct
    20941 cttcatgtaa tcataagctg catctactaa tttaactgtt ttttgcaagt caatgatgta
    21001 gattccgttt ctttctgtga agatatattt cttcattttt ggattccagc gacgagtttg
    21061 gtgaccaaag tgtacgccgg cttctagtaa ttgtttcata gaaattactg ccatgtttgt
    21121 ttcctccgat ttggttttat ttttcctctt cttatcttct accttgccgg caaacttttt
    21181 caagcaccta ccgacaatcc aataagaatg tggatttgct gatgcataaa gcaccctcag
    21241 ctattataca gacaaaagat ccgtatcgca agagcaaata tacttttctg ctcaacattc
    21301 aatagtttac ctgaaagata aaaagaattc aagaaaaaca gtagatttct ctttgtttct
    21361 ttattatcct ttttccataa aataatttta ggtataaaag acgaatatta ttgggcaatc
    21421 cttctttttt ttgttatgat acatgtgaaa tctttcgtaa aggagaaaga aaatgcgcaa
    21481 agctcaaaga catttgctga ttaaacaagt cattgaagaa ttcccgatcc gtacgcaaga
    21541 agaactatta aacaaacttg ggcattatgg cgttaccgcc acgcaggcaa cgatttctcg
    21601 agatatccgt gatctaaaaa tcgtgaaggc acctgatgaa aatggcgttt cccgcttcgt
    21661 attgtttcgc gaaaaaggaa ctcctgagac taggactgag gaagaggatc ggctggttca
    21721 aatgattgaa gacattgtat tgaaagtcga acgagtccac tttttgacga tcgtcaatac
    21781 cttgccagac aatgctcatt tatttgcatc tgttttagat gagatcaaac ctccctctat
    21841 tgtcagtaca attgctggat tcgatacgat catggtcatc tcggaaaatg aggaggacgc
    21901 aaaacgagta gaagaatttc ttcaccatcc aactgaagta tcactttttt aatcagagca
    21961 cgtattccta atatggaatg cgtgtttttt tattttcaat attttcctta ttgaataaac
    22021 ctttacactc tttacaaaaa tacatcattt tttattcaaa tttttcaaca ccttgattga
    22081 atcacaataa tcatcattta tattggatgt taacaagagc agcttcttgc tctttgtgta
    22141 tttcaaaaaa gaaatgaaag gaaatcatat gtataaatta ttaacttctg gaccattgac
    22201 gacttctgaa acagtgaaaa atgctatgct gatcgatcat tgtacttggg atcaagaata
    22261 caaagaaatt acacaatgga taagaaaaaa attattggat cttgctcaag tatcggaagg
    22321 aatatacaca acggtcttaa tgcaaggtag cagctccttc ggggtagaat cggtattaag
    22381 ttctgtgatc aggccagaag atactgtact gatttgttca aacggcgcat atagacaacg
    22441 aatgatcaac atgtgcgaat gtctgaaact gaactatacc gtttatgagg tatcggaaca
    22501 tcaaatcctc caagctcatg tgattacaca gctgattgaa gagaatccgt ctatctccgc
    22561 actagcaatg gtccatagcg agactacttc cggtattttg aataatttgg aagagattgc
    22621 tgctgtcaca caagaaagag atcttttgtt tatagtggac gcgatgtcaa gctttggtgg
    22681 gataccgatt tgtgtagccg aactagggat tgattttttg atttccagct caaacaaatg
    22741 tattcaaggt gttccaggct tttcttttgt acttgctaat aaagcggaac tggaaaaacg
    22801 aaaaaatgtt agccgaagtt tgtcacttga tctatatgac cagtaccgcg tgatggaaaa
    22861 cgagaatggc aaatggcgtt tcacttcccc tacccatacg gttttggctt ttcaacaagc
    22921 gctgaaggaa ctagaggcag aaggaggaat cgaaactcga tattcacgtt atctcgccaa
    22981 taatcatgtg ctacgacaaa aaatgacaga gatggggttc cagcctttca ttcaagaata
    23041 tcaggggcca ttcatcacct cttttcttta ccctaaggac tggcgatttg attttaatca
    23101 tttttatcag tatttaaagc aaaatggatt tgtgatctat cccgggaaaa tcagcgatca
    23161 tgaatgtttt cgtatcggaa atattggcga gatctatccg gaagatattt tggaactgac
    23221 agcaattatc aaagactata aggagaacgt taatgattaa aactgtaatt tttgattggg
    23281 caggaacaac tgtggacttt ggctgtatgg ctcctgtcca cgcttttaga aatgcttttc
    23341 tagaaaaagg aatccaactg actgacaaag aaatccgcta accgatggga aaattaaaat
    23401 gggatcatat ccaacagctt ctttccctcc cttctgtcaa aaaacaatgg atagctattt
    23461 atggacaact acctcaggaa aaagaggtgg aggaattgta tcaacaattt gaacattatc
    23521 tgtttaaaga tttggtcaag cattctacct tgaaacccga cacattggaa acgatcgaac
    23581 ggttgagaaa cgctgggatc aatattggtt ccacgaatgg atttaatgct cctatgatga
    23641 caatcgtagc agaaaccgca aaaaaagaaa ggtattcacc agacttcatg gcaacttttg
    23701 aagacgtcga agggtatggt cgaccgtttc cttatatgat ccataaaaac atgcagtact
    23761 tcaaaaacaa gtcggttgat gaagtaatca aagtcggaga tacggtctca gatatccagg
    23821 aagggaaaaa tgccggagtg ttgacagtag gtgtaattga aggtagttcg ctaatgggga
    23881 tttcttatga tgagtaccaa aaattagaga tggggaaaaa gatcgtttaa aacagtctgt
    23941 tgctcttaga ttccaacaag ccggcgctga tatttgtgta aacaatttaa aagagttaac
    24001 agaatacatt ttgtacgctg acatgaatcc agaatgactt ttatacaaaa taagaggttg
    24061 tgaaaaagct gtcctgtatc aagtaataaa aacagccaag caaaaatagc tcctcatatt
    24121 tttcgtttgg ttaggcttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    24181 aaaaaaggga gctgtgacac gacttttgtc acagtcccct tatttgcaaa caaacagtgt
    24241 ttaagagaca acctctccac taaacggtgt tcattcagct gactctcggt atttgctcaa
    24301 aaaacgataa aatttgaaaa gctattttct cttttgtttc tctaatactc ggatcagaac
    24361 gctgatttca cattctcttt ttcttacatc ttatctggtg catgaagtcc tagcaaacga
    24421 aggtcttctt tcaataatac agtcactgca taaactagag ctaagcgtgc ttctttttgt
    24481 tcatcatcag ctaaaatctt cgtatgagca tagtatttgt tgaatgcttg tgctaatttg
    24541 attgcatgtt tcgcaatcac tgacggttcg tatttttccc cagcagacaa gaccgtttca
    24601 gggtattttt gaactaattt aaccacttcc cagctggtat cgtcattcaa tgcatagtct
    24661 gctgtttctg aagggacaaa tcctgctttt tccaacaggc tgactgcacg agcatgtgta
    24721 tattgcacat aaggtccagt ttctccttca aatcgaacaa cttcttccag gttaaagtca
    24781 aatgtattca gtcgatcgtt tttcaaatcg tggaaaatga ctgccccaac cccaacttgt
    24841 ttagctacag catctttgtt ttccaaatca gggtttttct cgctgatttg ttctttagca
    24901 gattggattg cttcatttaa tacttcttct aataagacga tctttccttt acgagttgat
    24961 aattttttac caccttgcgt gatcaaacca aatggaatat ggtgcatgtc gtcagaccag
    25021 tcaaagccca tttccttcaa gacagctttc aactgtttaa aatgatagct ttgttcattc
    25081 cctactacat atagagattg tttgaagtcg taagtacgtt tacggtacaa tgcagcagct
    25141 aagtcacgtg taatgtatag tgtcgcaccg tctgacttct taatcaacgc tggattcagg
    25201 tcataagcag ataggtcaac gatctctgca cctttatcct cgttcagcaa atgtttttct
    25261 tctaaaagtt tgacgatttc atccatcttg tcattgtaga aagcttcacc gttcaacgaa
    25321 tcgaaacgta cttccagcag atcatagatt ttattgaatt ctttcatcga ttcatcacgg
    25381 aaccattgcc ataattgaat agcctcttta tcgccttctt ccagacgttt gaaccaagca
    25441 cgagcttctt catttaattc tggttctgtt tcagctactt catggaattg gacgtataaa
    25501 cgaagcaatt cattgattgg ttctgcttta acagcttctt ctgtacccca ttttttgtaa
    25561 gcgacgatca gttttccaaa ctgtgttccc cagtcaccta aatggttgat gcggattggc
    25621 tgataaccga ttttttccat aatgaaaccg atcgaattac cgataactgt cgaacgcaaa
    25681 tgtcccattg agattggttt ggcaatatta ggagaagaca tgtcgattgg tactgttcct
    25741 tgattcccga tgttgctatc cccataatgt tctttttctt tcactactgt ttgcaaaact
    25801 tttttgctga taagttcttt attcatgaaa aagttcaagt aaggtccgac aacttcgatt
    25861 ttttcaaagt tggcagaatc gattttttct gctaaatctg cagcgatttg ctgtggcgct
    25921 tttcggtaaa cttttgctaa tgaaaaggct ggaaatgcaa catctccgtg ttcagctgat
    25981 tttggatttt ctagtaattg ctcgacttgt tccagtgtta aatcatcttt gacagcgtca
    26041 tagacagctt ttgcgacaag atctttatta ttcatcttta ttcctcctaa agtgttccct
    26101 tgattgttaa acaaaaaaaa tctctagcga cggcatactt agtatgccat cactagagac
    26161 gagatttccc gcggtaccac tccaattgtc ctaaaaaagg accagctcca tctgatatcg
    26221 gtagacgacc gtctgtttaa aacagaattc tccaagtgcg cttcgttgta tcttcttcat
    26281 tcggcttcca ccacttccga attcgctagc caagaatgat acaagtactc tcttgttcaa
    26341 caaatcttag tcttattaaa ctttcttgaa ttatatcaga aaaaaaaacg aaaggctagt
    26401 cgtttcataa aaaaacaatc cagatggcct aaaggagaag aaataccacc tggatagcta
    26461 taaatcattt cgtaaatacg aaagacttaa caaattaatc agctacgata atcgttcctt
    26521 cttcagaagc taaaagattc tcgatatttt ctaaagaagt gatgattgcc ttagcgtttg
    26581 gttttgcttc aacaaatgca atagctgctt ctactttcgg aagcatgctt cctggagcga
    26641 attgcttttc atcaatgtat tgtttcattt ctgaaacagt aacagtttct aatttctttt
    26701 gatctggttt ttggtaattg acatacacat tgtctactcc tgtcaatacg atcagcaaat
    26761 ccgcatcgat gatttcggct aatttttctg aagcaaaatc tttatcgatt acggcttctc
    26821 gtccttctaa tccagtagct gtttctacaa caggaatccc accgccacca acagagactg
    26881 tgataactcc ttgatcgacc agcgtttcga tgacacgtgc ttctttaatc gagatgggtt
    26941 taggggaagc gactactttt ctccatccac gtccagcatc ttctttgaat gtcacagtgg
    27001 agtcagcatt catttgttct ttggcttctt cttccgtgta gaatggaccg actggtttac
    27061 ttggattttt gaatgaagga tcattttcat ccacaataac ttgagtgact aaagaaacca
    27121 catctttatc gatccctttt tccttcagta cttcgcccat ggcgttttgt aaccagtaac
    27181 cgatagatcc ttctgtcatt gcaacacatg tatctaaagg cattgccggt gttttctcag
    27241 aatcagcagc ttgctgctga atcaataggt taccgacttg cggaccattt ccgtgggaga
    27301 tgatcaattc atctccttgt tcgataaatt tcactaaata ctttgctgtt tccattaacg
    27361 cttcttgttg ggcttttgca cttgcatccg tagacaagat ggcattgccc cctaaagcga
    27421 caactacttt tcgtttggcc atttcattcg tcctttcttc agttctaccg aattttctag
    27481 ataacaaaac gagccagcgt tttgtgattt tccctcaatg ctgactcgtt ttttcgtgag
    27541 atgaatgtgg ttatgcttaa acgcgaggga taaacaagtt acctaatgtt gctgccatga
    27601 tcgctttgat tgagtgcata cgattttctg cttggtcaaa ttgacgagca tatttgctgc
    27661 ggaagacttc atctgttact tccatttcag tgatgccaaa gcgttctttc atttgttcac
    27721 cgtaaacagt gtttgtatca tggaaagctg gcaagcagtg caagaagatc aaacgatctg
    27781 tgttgtgtgt tttttctacc atttccatat tgatttggta aggtttcaac aatttgatac
    27841 gttcttcgaa tttatcttct tcacccattg atacccatac atcagaataa aggacgtctg
    27901 ctccgtctac acctttatca acatcgtcgg taatcatcaa ttgtgcaccg gatttttcag
    27961 caaagccttc tgccattttg acgatttctt cttcaggttg taattctttt ggtgcaacga
    28021 tacgcatatt cgctcctaaa attgcacctg tgactaataa agagttagcc atattgtttc
    28081 gaccatctcc gcagtaagca acagtgatac cttctactgt tccaaagttt tcttggatag
    28141 ttaaaaagtc agcgatcatt tgtgttggat gccattcatc agtcaagcca ttccaaactg
    28201 gaacaccaga gaattctgct agttcctcta ccattttttg actgaatcca cggaattcga
    28261 ttccgtcaaa catacgtcct agtactttag ctgtatcttc tgtggattct tttttaccta
    28321 attggatatc atttgcacct agatattcag gatgtgcacc tagatcgatc gctgcagtag
    28381 taaatgcaga acgagtacgt gtagatgttt tttcaaataa aagcgcaata ttttttcctt
    28441 ctagatagtg atgtgggata ccacgttttt tcaagtcttt caagtgttct gaaaaatcga
    28501 tcaaatattg taattcttct tttgtaaagt ctttttctgc taataagctt cttccttgga
    28561 atactgattc tttcatatta aacattctcc tttagattgt ttttatttaa gattaaagag
    28621 gaaatcccga cggcagctga cagtaagact gccgtcagga aacaaattac ttcaagtctt
    28681 cacggacaag tggttggctc atgcagcgtg gaccaccacg acctcgtgac aattcacttg
    28741 aattgatttc taacactttg atgccatagc tacgaagcaa ttcgttcgat acataatttc
    28801 ggttataagt gactacaaca cctggagcga ttgccaatgt gtttgatcca tcattccatt
    28861 gttctcgagg tgcaacgatc tcatctccat taccagttgg gatcagtaca agatcatcta
    28921 atccaagagc agctttcatc gtttcgtgta agttatctga atgagtaatc ttgatatcat
    28981 caccatctgg ttcgattgta aagacatcca tcttaccgtc tttactttga attgctggat
    29041 ggatagtgaa tttatcgtga tctaccattg taaatacggt atccaaatgc atcattgcac
    29101 ggttgttcgg aattttgatt gccaacactt tttcaaatcc tgaatttttt gcgaataggt
    29161 ggcgtgctaa tttttctaaa gctttcgcat tagttcgttg agaaatccca acagctacta
    29221 ctttatcgct taagatcaat tcgtctccgc cttcgatatg atctggattt tcacgatcca
    29281 accatacttc gattccttta tttgcaaatc ttggatgatg tttcaaaata tattctgtaa
    29341 acatcgattc acgacgacgt gcttcaaaag tcatcttatt gactgtcatc ccatttccca
    29401 ttgatgcgga agggtcgcgt gtaaagtaca agtttggcat tgggtccatg taaaatggat
    29461 agtcatcgtc tgctgacaga tcatatagac tgctagaacg tacttcgata tcttttgtac
    29521 gaaccccagc catgatttta tctaccattt cttgcgtttc cattgataga aggaactcat
    29581 gaagaccctc tcttacagca ttcgatgcaa tatgagattc atccaacatt ttattcaaga
    29641 attgttcttt gacattgcct gcgtcaatcg cttctgccgc taatttttcc aagtaaagag
    29701 tctcgacgcc ttcattttgc aatgtcttcg caaagttgtc atgttcttct tgagcaatcg
    29761 gaagatatgg aatatcatcg aacaacagac gatccataat atctggtgtc aaattttcca
    29821 cttcttgtcc aggccgtttc agtaaaactg tctttaattt ccctatttca gagaaaacgt
    29881 gaataggttt atccatgttg tgttgcctcc ttctttttga ttacatgtat aggatatcct
    29941 ccttttgtaa tcactttcat aattttgtct cattcaaaat g
//
LOCUS       DAJSMK010000026        29111 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.026, whole genome shotgun sequence.
ACCESSION   DAJSMK010000026 DAJSMK010000000
VERSION     DAJSMK010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.026"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..1031)
                     /locus_tag="ON488_001183"
     CDS             complement(<1..1031)
                     /locus_tag="ON488_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3231387.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFATSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1113..1802)
                     /locus_tag="ON488_001184"
     CDS             complement(1113..1802)
                     /locus_tag="ON488_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCR3231388.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ON488_001185"
     CDS             complement(1908..2276)
                     /gene="rplL"
                     /locus_tag="ON488_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HCR3231389.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2329..2832)
                     /locus_tag="ON488_001186"
     CDS             complement(2329..2832)
                     /locus_tag="ON488_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HCR3231390.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3036..3163)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ON488_001187"
     CDS             complement(3242..3931)
                     /gene="rplA"
                     /locus_tag="ON488_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HCR3231391.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ON488_001188"
     CDS             complement(4035..4457)
                     /gene="rplK"
                     /locus_tag="ON488_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HCR3231392.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4800..5468
                     /gene="sdaAB"
                     /locus_tag="ON488_001189"
     CDS             4800..5468
                     /gene="sdaAB"
                     /locus_tag="ON488_001189"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HCR3231393.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5481..6353
                     /gene="sdaAA"
                     /locus_tag="ON488_001190"
     CDS             5481..6353
                     /gene="sdaAA"
                     /locus_tag="ON488_001190"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HCR3231394.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6444..7463)
                     /locus_tag="ON488_001191"
     CDS             complement(6444..7463)
                     /locus_tag="ON488_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HCR3231395.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7636..8541)
                     /locus_tag="ON488_001192"
     CDS             complement(7636..8541)
                     /locus_tag="ON488_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCR3231396.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ON488_001193"
     CDS             complement(8600..9145)
                     /gene="nusG"
                     /locus_tag="ON488_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HCR3231397.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ON488_001194"
     CDS             complement(9246..9416)
                     /gene="secE"
                     /locus_tag="ON488_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HCR3231398.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ON488_001195"
     CDS             complement(9440..9592)
                     /gene="rpmG"
                     /locus_tag="ON488_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCR3231399.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9754..10398
                     /locus_tag="ON488_001196"
     CDS             9754..10398
                     /locus_tag="ON488_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCR3231400.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10454..10957)
                     /locus_tag="ON488_001197"
     CDS             complement(10454..10957)
                     /locus_tag="ON488_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCR3231401.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10970..11016)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11554..12519
                     /locus_tag="ON488_001198"
     CDS             11554..12519
                     /locus_tag="ON488_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCR3231402.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12618..13790)
                     /locus_tag="ON488_001199"
     CDS             complement(12618..13790)
                     /locus_tag="ON488_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231403.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13777..14922)
                     /locus_tag="ON488_001200"
     CDS             complement(13777..14922)
                     /locus_tag="ON488_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231404.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14936..15868)
                     /locus_tag="ON488_001201"
     CDS             complement(14936..15868)
                     /locus_tag="ON488_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231405.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15985..17064
                     /locus_tag="ON488_001202"
     CDS             15985..17064
                     /locus_tag="ON488_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCR3231406.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17061..17690
                     /locus_tag="ON488_001203"
     CDS             17061..17690
                     /locus_tag="ON488_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3231407.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17800..18027)
                     /locus_tag="ON488_001204"
     CDS             complement(17800..18027)
                     /locus_tag="ON488_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCR3231408.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18130..20718)
                     /locus_tag="ON488_001205"
     CDS             complement(18130..20718)
                     /locus_tag="ON488_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HCR3231409.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20738..21397)
                     /locus_tag="ON488_001206"
     CDS             complement(20738..21397)
                     /locus_tag="ON488_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCR3231410.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="ON488_001207"
     CDS             complement(21446..21949)
                     /gene="trmL"
                     /locus_tag="ON488_001207"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HCR3231411.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22170..23036)
                     /locus_tag="ON488_001208"
     CDS             complement(22170..23036)
                     /locus_tag="ON488_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCR3231412.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23145..23786
                     /locus_tag="ON488_001209"
     CDS             23145..23786
                     /locus_tag="ON488_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HCR3231413.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="ON488_001210"
     CDS             complement(23848..25209)
                     /gene="mgtE"
                     /locus_tag="ON488_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HCR3231414.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25227..26126)
                     /locus_tag="ON488_001211"
     CDS             complement(25227..26126)
                     /locus_tag="ON488_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HCR3231415.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26128..26925)
                     /locus_tag="ON488_001212"
     CDS             complement(26128..26925)
                     /locus_tag="ON488_001212"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HCR3231416.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26903..27607)
                     /locus_tag="ON488_001213"
     CDS             complement(26903..27607)
                     /locus_tag="ON488_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HCR3231417.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27738..28313
                     /locus_tag="ON488_001214"
     CDS             27738..28313
                     /locus_tag="ON488_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HCR3231418.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28431..29108
                     /locus_tag="ON488_001215"
     CDS             28431..29108
                     /locus_tag="ON488_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HCR3231419.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8567 a         6169 c         5231 g         9144 t
ORIGIN      
        1 aatacagtat tatttcggtt gcttgctgct tcacctagcc cttgtactcg tgtttgattg
       61 gcgacttgac caaattgatt cccgacgtct aataaaataa tagctaaaag caaaatggcc
      121 aaatggcttc cgccaaccaa taaagcaata aagcttattg tttgcataac aagtcccata
      181 tacacgattt ttctttcaga ataagaatct gccagtcgtc ccacgatagg tgcagcaact
      241 gctccagaca aaccaaaaat cgctaatatc cctgcttcga atgttcccca attgtaggcg
      301 ggactgctga tataaaaaat caacgtagac caaaagatcg aaaatgttcc aaacatgaaa
      361 aatccactga ctgccgcttc tcttaataga cgttgagaag caactaaatg cggcaaactt
      421 ttaagtgaat caaggtatga aacagctgta ctactttgct ggacagaacg cggcattttc
      481 cagtaaagca gaagtgtaag aattccgact gcacataaag caaataaata gatcatccgc
      541 caagaaaaaa gactggcaac aataccagat accgtccgag aaagcaaaat ccccacgagt
      601 aaaccgctaa gcaatgtacc catgaccttc cctcttgctt ttggtcccgc tagtaccgca
      661 ccgtaaggaa tgatgatttg cggcacgatc gaaagtaatc ctattaaaaa agaagcgcat
      721 gcaaataacg taaacgaagt cgcaaaaaaa gcggccaaca gagagacggc agataacgct
      781 accattcgaa tgatcaattt tggacgatcc accacgtccc ctaaaggaac taaaaacagt
      841 aaccctaacg catagcctaa ttgggtcaac atcgtcaata tcccgactgc acttgtgcta
      901 acagataaac tagctgctac ttttgttcca atcggctgga tgtaatacat attggcaaca
      961 acaacgccac aagtgattga taatagtaaa ataagcgaag ttgttaaagg tgttttttca
     1021 ttactcttca ttgatttccc ccatttccta tcttagttta caacttatgg aaaagattgg
     1081 aaatagaaaa atacaactat tcgccacact tattatttgt gcttttgttt tccttgtttt
     1141 ttcttgcgat ctttataaat gaagacaact aaccctacta gcacagtaac acttgcaacc
     1201 aacgtgactg cagttttgtt atatccgtga aacagagctt ctccaccaca cgcatacaac
     1261 acagacgaag ggatgactcc aatcacgatc gacaatatga tttgctgtag aggcaatttc
     1321 atcgcatctg cagcaaaatt gaccatagaa gatggaataa ccggtatcat atagcctaac
     1381 attacaccta tttttggatg tttcatttgt cggattgctt gcacccaatg attcgtttcg
     1441 gttttcttat ctaaaaattt taagcgatgc ataaggaaaa ttgcagtgat gttaccaaga
     1501 gcattaccca aaatgttgat gatcgcacct gtcagtggtc caaagctcaa accagcaatg
     1561 actccaacta ctgaagtagg aatacctgga acagcacaca tcaccgctgt caatacgatc
     1621 aagagtatcg atgcaaaagt cccatgcgaa cgaatatgtg cgagtagctc tgccttactc
     1681 gctctcggat ttaaaaataa ttggatgtct gtctgatatt ctaaatacaa ccgatagccc
     1741 actaccagta tcagaatgat tcccaacgag atcaacatca atcggattat tttctttttc
     1801 atatttcctc ctgaaaaaaa tctatattca ttaaataata gtttaacata aaaacaaaaa
     1861 agcaccgaaa tccaacatag gatctcagtg cttttaaata gtaaaaatta tttaacagtt
     1921 acagatgcgc caacttcttc aagtttagct ttcaattctt cagcttcttc tttagatacg
     1981 ccttctttaa ctggtgcagg agcgccatca actacagctt tagcttcttt caagcctaaa
     2041 ccagttgctt cacgaactgc tttgataact ttaacttttt ggtctccagc tgcagttaat
     2101 tctacagtga attctgtttg ttcttcagca gcagcagcgc caccagcagc agctacagct
     2161 acaggagcag cagcagatac gccaaattct tcttcaatag ctttaactag gtcgttaagt
     2221 tctaggatag ttgcttcttt taactcagca acgatgtttt caatgttcaa tgccattata
     2281 atttcctccg tttaattgtt cttttttatt taatgcttta tgcggcaatt aagctgcatc
     2341 tccatcttct ttgtctgcca ctgctttgac agcgtaagcc acgttgcgga ctggcgcttg
     2401 tagtacagat agcaacatag atagaagtcc ttcgcgattt ggcaattttg ccaatgctgt
     2461 gatttcttcc aatgaagaga ctttaccttc gatgataccg cctttgattt ctaatgcttt
     2521 tgcttcttta gcaaattcgt ccatgatttt cgctggtgcg actacatctt cgttactgaa
     2581 tgcaacagct gtaggtccag tgaatacttc gtccatgcct tcaaggccag cttttttagc
     2641 tgcacgtgaa agaatagaat ttttgataac tttcatttct acgttagcat cacgaagttg
     2701 tttacgtaaa cgtgttactt catcaactgt taatccgcgg tagtcaacga ctactactga
     2761 tgcagctgct gtaaattttt cgcttacttc atcaacgatt gctgcttttt ttgcgataat
     2821 tgcttcactc atttttgagt ttcacctcct gaattttgat ggaagagttt tttgcactga
     2881 aaaggcaagt cacttttata gttactttgc tcaaccagta ttattcatca cctattcact
     2941 tcgttcatag tgattctact cgctttgctc gaaaggaaac tcctttcgct ttgctcaacc
     3001 agtattgttc atcatctctt cacttcgttc atagtgattc acaataaaaa actctatgcc
     3061 accgcagaca tagagggact attgaatata ttcaataaac gtcctcggta ggaaattaag
     3121 gcttgatgcc acctactgtc ttcggtacaa gttaattatt aacctcaact agcttagcat
     3181 gctaaactag ttgagtcaag aattattttt cagttggatc aatcaacatt ctaatattta
     3241 attagaaaga agcttggtca acatggatac caggtccaaa tgttgttgtg atcgttacat
     3301 ttttcatgta ttgaccttta gctgctgatg gtttagcttt tagcaataca tcatggattg
     3361 ctgcaaagtt ttcaactaat ttttcatcgt caaatgaaac ttttccgatt ggtacatgga
     3421 tatttccagc tttgtccaca cggtaagtta ctttaccagc tttcacttcg tttactgctt
     3481 ttgttacgtc cattgtaact gtaccagttt tagggtttgg cattaagcct tttggtccta
     3541 atactcgtcc tagacgacct acagtagcca tcatatcagg tgttgcaaca actacatcaa
     3601 agtcaaacca tccgttttgg attttttgaa ccatgtcgtc gtcacctacg aaatctgcac
     3661 cagctgcttc agcttctttt gctttgtctc ctttagcaaa aactaaaaca gtttgtgttt
     3721 taccagttcc gtttggtaat acaacagcac cacggatttg ttggtctgct tttttagggt
     3781 ctacgttcaa acggtatgca acttcaactg ttgcatcaaa ttttgcaatg tttgtttctt
     3841 ttgctaaagc tactgcttcg gcaacaggat aaactttact tgaatcaact ttttttaatg
     3901 catcttgcat ttttttgctc tttttagcca ttttggttcc tccttgattg tggttataac
     3961 ggttgtacct cccacgtgtt ctatatcttt caatatagag ccaactgaga agctgctgtc
     4021 ttagggtgta tagattattc tacagtgatc cccatgcttc gtgcagttcc ttcaaccatg
     4081 cgcattgctg cttcaacgtt agctgcgttt aggtcttcca tttttaattc agcgatttct
     4141 cttacttgat cgctagaaac tttcgcaact ttatttttgt ttggttcgcc tgaacctttt
     4201 tcgattttag ctgctttttt caatagaaca gcagctggcg gtgtttttgt aacgaatgtg
     4261 aatgaacggt cttcgtatac agaaataaca accggaatga tcaaacctgc ttgatcagct
     4321 gtacgagcgt tgaattcttt tgtgaatccc atgatattga tacccgcttg acctagtgca
     4381 ggacctactg gtggagctgg agttgcttta cctgcaggaa tttgcaattt aacgattttt
     4441 tctactttct ttgccacgag acatacctcc ttaagtccgt gatgtggtta attggagatg
     4501 catatttctc ctcccacgtt ttatctgatc tgaaaaaatc cagacaaata atgtgcaaaa
     4561 caatgcacac tggtacagta tagcaaattt atttgttttt tcaagatttt tttctgctat
     4621 ttttacattt tgcttgaata aacgctaaat ttattctaaa aaaacaacaa tttttcgttc
     4681 tcatttcttc ttttatgtta cacttgcgct agcatggttc aacagatgaa agcaaacaat
     4741 aacacggttt tttagaccct tgtacaaaga ttcctacata acaaaatgag gtggagaaaa
     4801 tgaaagattt aaggtataga agtgtctttg atattattgg acctgtgatg attggtccaa
     4861 gtagctctca cactgccgga gctgctagaa tcgggaaaat catacgtagt atatttggcg
     4921 aacagcctga ttctgtagat atttatctat atgaatcatt tgcaaaaacc tatcgggggc
     4981 acggaacaga tattgcatta gttggcggcc tgttagggat ggaacccgat gatgaacgtt
     5041 tagctgattc tttgaaattg gcatatgaag ccggtatgga agtcttgttt gttcctaaga
     5101 gtgaaaaagc cgaacatcca aactctgtaa agatgcttct aaaaaaagga acacgaaagc
     5161 tttcagtcac tggcatttcg atcggcggtg gcaatatcca gatttctgaa ttgaatggat
     5221 tcaaaatttc tttaagcatg ggtactccta ccttgatcgt tgtccaccaa gatgttccag
     5281 gtatgattgc taaagtgact agtatacttt ctgagaccaa tacgaatatc ggcactatga
     5341 cagtgacacg ggaatcaaaa ggtgaaaatg ccattatgat aattgaagta gatgatcctc
     5401 aagtagaaga aacggtaaaa agactcaaac agctgccaaa tatcgacagc gtaaattatt
     5461 tcgattaagg agctaaaaaa atgtttttat cgattgaaga attagtagat caagcaaaag
     5521 cttatccaag tgtagcagaa ttgatgattg cagttgaaat ggaaatgagt ggccgttccc
     5581 gtagtcacat catcgagatc atggaaaaaa acctctcagt aatggaacaa tcaatcaacg
     5641 agggaaaaga aggtgttacc tccgtcacag gaattaccgg tggtgatgca aaaaaattag
     5701 atgattattt aaatgaggca gactttttaa gtggagaaac aatcttaaaa gctgtacgca
     5761 atgctgtagc tgttaatgaa gtcaatgcaa aaatggggtt gatttgtgct acaccgactg
     5821 ccggaagcgc gggtgttgtt cctggtgtgc tgatggctgt ccgagatcgg cttgatttga
     5881 cacatgaaca gcaattggaa ttcttattta ccgctggcgc tttcgggtta gtcatcgcaa
     5941 acaacgcttc tatcagtggt gcagaagggg gatgtcaagc agaagttggt tctgcaagtg
     6001 caatggcagc agcagctttg gtttgtgcaa aaaatgggac tcctcatcaa gcagcacaag
     6061 cagtagccat tacattgaaa aatatgatgg gactgatttg cgatcccgtt gcaggcttag
     6121 ttgaagtccc gtgtgtcaaa cgtaatgctt taggctcttc tcaagctttt atctctgctg
     6181 atatggcatt agcgggtatc gaaagtgtca ttccgccgga tgaagtcgtt gctgcaatgt
     6241 accaagtcgg acgtcaaatg ccgtcgattt tcaaagaaac agcagaaggt ggcttagctg
     6301 ttacgccaac tgctaaacga cttgcggaag agattttaaa taagagggcg tgataaagct
     6361 ccttaatttc gagtattaag agattagtta tcttcataac aaaaaacgaa gagaggacta
     6421 attgcccttc tcttcgtttt ttattaatcc atcaatttcg tattttttac ttcatcgatc
     6481 gtttttgttc ctgcaagttg catcgtgatc gacaattctt tgttcaggtg ttcaaaaaca
     6541 gatgttactc cttctgcccc acctagattc aacccataaa tcactggtcg gccaatcgca
     6601 actaagtcag caccacttgc cagagctttg aagacatgct ctcctcgacg gacaccagag
     6661 tcgaaaatca ctggtacacg tttgttgact acttcggcaa tttttggcaa tacttcaaag
     6721 gacgcaggac ctccatctaa ttgacgtcca ccatgattgg atacccagat accatctgcc
     6781 cctgcagaga tagcgattac tgcatcttct ggcgattgta ttccttttac gataactgga
     6841 agatgggtga tttctttgat tgttttgatg tcatctggtg tcaagccttg ttttgcagct
     6901 gcataaattt ctgcgattcc ttttccttcg ccattaccac ttgcactttg ttcgctatac
     6961 gcagctaagt taggcattgg taatggaaat tggaattgat tgatgacgtc ttcttcacgg
     7021 taaccaccga gcgttgaatc tgccgttaaa atgatagctt tagcccctgc ttctactgct
     7081 ttgttcaaaa tgaactcatt gaatctgtcg tctttactca tatataattg gaaaaactgc
     7141 ggtgcgcctg gcgctgcatc ggctgcgtct ttgattgtcg tatttgcata agtgctgatg
     7201 gaaaagattg atccagcagc agctactcct ttagctgtat cagcttcccc tttttcatgt
     7261 gccaatcctt gggccgctga tggcgcttgg ataatcggtg tatctaattc aattccgaaa
     7321 acagatgtat gcaaatcggc tgagtcgatt ccgcgtaata tccgtggcat gattttcttt
     7381 gtattaaaag aagtcgtatt ttctttcatc gtccactcat cttcagaacc accgcgaata
     7441 tagccaaaag ctcctgcttc catgcgctct tttacacgac cttctagtta ggcaatgttt
     7501 acaatatcga ttggatgttc ttcattactt gtatgataag tcatagtaga tccttctttc
     7561 atcttcttga ttacatataa atcatactaa acttacaaaa agtaagcaaa catttactct
     7621 cagatacttt tatcgctatt ctttccaaat aaatcgactt acaagctgat ctacttcttg
     7681 gttttcatga agcatactat gagaggcatt ttcacctgtc actacttttt cctctatttc
     7741 atttccgcgt tgcttcaaca acgcatagac cgctaatgca ctgtttaacg gtactgttcc
     7801 atcactcaag tctgtttcat ctagttgacc agcaatcaag aaaaatcgag tggttatagg
     7861 aatattaccg atcatttgct ggtaatcttg atagcggtta gaaacgacag caggcccctt
     7921 tgctaactca tctgtcagag actgcgcact atcatcgaca aaatcattaa aaggcgcgcc
     7981 aattgctgtt aatgtctgaa cttgtggcaa tgacgtatcc tgtccatacg ttcctaaata
     8041 gcgtagtgca ctaactcctc ccatggaatg ccccactatg ttgactttat ctatgccgta
     8101 gttttctttc agatacaaaa gacaagtttt gatccattct gcttgattcc actcgttatt
     8161 tttattatct tcaaacaata cttggaccat cggattgtct gcttttccag acaaatctcc
     8221 tgttgcttgt atttgtccat ctgttcctac tgttaaaacc aattctttta ctgcttgctg
     8281 atttttttcc aaacgccgca acatcccttt aaaggaattt tctgtcccgc tgtagccgtg
     8341 gaaaaaaagt gttggaatag tggttttttc tatcacttta ctggattctg ccgttttttc
     8401 tttatcagaa acttcagtag tatttatctt cgtcgtctgg caaccactta acgcaaacaa
     8461 actgataagg actaaagctg ctgcagttgc acgtttgcat aaatttttga ttggttctgt
     8521 catacacctc ttcctttcca tatagaaaaa agaaagactt gaaaggccaa tcatatgatc
     8581 gacatttcaa gtctctttat taatcgattt tatctacttg atcgaaatca agttctgtac
     8641 tggtttcacg tccaaacata tcgatgttga ctttcaattt ttctttttct ccgtcaactt
     8701 ctgttacttg tccttctaat ccagcaaatg cgccttcgat gattttcacg acttcgccaa
     8761 cttctacttc tagatcattt tgtcgcaggc tcataccgat agaacgcaag atatgattga
     8821 cttcttctgg aagtaatggt gctggtttgc ttccggctcc gtgtgaacca acgaatcctg
     8881 tcacaccagg tgtgttgcgg acaacatacc atgaagcgtc tgtcatgatc atttcaacaa
     8941 gtacgtatcc tgggaatgtt ttatgaacga tttctttttc tttcccattt ttgacttcag
     9001 tttctttttc ttcaggaaca acgacacgga aaataaagtc ggccattttc atactttgcg
     9061 cacgagattc gatatttgct tttactttgt tttcatatcc tgaatatgta tgcaagacat
     9121 accagttttt ttcaaaagat tccattgaag gctcctcatt tcattgtaaa ataaaaaaac
     9181 ctcagtacac ccgaagtttt tctttcgctt cattatagca ctaaaagtac gttgtggcta
     9241 gcgagttatt ttaaaatcca gccaaataag ctttggatgg ctgtatccat tacgtaaaac
     9301 atcaatccga aaataataga agtttcgatg actactaacg tatctttacg gagttgtttt
     9361 ctgcttggcc aagttacttg tttgatttca tcttttacgc tttttagaaa tttcatgaga
     9421 caacctccct tgctactgtt tatttcgttt ctttatgtaa tgtatattga ttacaatatt
     9481 tacaaaactt attgatttcc aaacgttcgc cgctttttcc ttcactgact gattttgtgt
     9541 agttgcgaga cccacaaacg gaacaagcga gtgctgcttt tttctttgcc atttacttct
     9601 gcccccttgc tgagaatcag acttatactt cataacagta tcacgtaact ttttacttgt
     9661 caatttgtga aataaactat ctattgtttt ggataaaatt atgatatgat taatttgaaa
     9721 ttaagctaaa atgagacaat tggaggtata gcgatgctat taaaaacact tgtatataag
     9781 aaaaaagatc tgacaaccgt tacagagact agtacattag aagaagcatt aaaaatttta
     9841 gaaacttccg gataccgttg tgtgccgatc ttagattctt caggtaatat tttccgtgga
     9901 aacatttaca aaatgcatat ctatcgtcat aaagcaaatg gcggtgatat gacgcttcct
     9961 gtcactcatc ttttgaaaaa cgctacaaag ttcatttacc tggatacttc tttcttcaaa
    10021 gtattcttta cgatcaaaga gcttccttat attgctgtcc ttgacagtga aaatcatttt
    10081 tatggtattt tgacacatag tacgttgctt aatatgctct ctcaatcttg gagcgtagaa
    10141 caaggaagct atgtactgac aattgcttcc acaggaaagc aaggagattt ggctgctatt
    10201 gcaaaaatca tttcaaaaca cagcagcatt gccagctgta ttactcttga tatcgaaaaa
    10261 gacgaataca ttcgacgtac attgatcacg ctaccggcta acactgaagc gaaagtatgt
    10321 gaaacgatcg tcaaccactt agagaaaaag aattataaag tggtagaaat tgaaaatttg
    10381 caaaaccaag aagcataatc aaaaagcgaa aaaagaaaac agctaatctg ctttcttttt
    10441 tcgcttttta taattagaca cgcttttcaa aatcaagcgc gcgatctaaa taatacatca
    10501 atggtgctga aacagccatg acgataaact cacttaatgc aagcgtgcca taggttgtcc
    10561 aaaatgcttg gccacctgtt ggaactaaca tataagcaat cagtcccatg ctgatggtaa
    10621 agaagatcgt gttcaatact aaacgcatct ttacattttt cactttgttt tgcaataaag
    10681 ctgtcaggcc taaagaaagc aatgtttggc cgccaccaaa aaccacatcc atgataccaa
    10741 aaccaaagaa ggcattatag acgatgaccc cgcctaaaac tccccaaagc aatttacggt
    10801 taaagacaac taaatgattc aaactttctg aaatacgaaa ctggatcggc cctgaggata
    10861 caggcgcaac taaaatagtt aacgctagat aaagagccat gatgatgcca tttacaacga
    10921 ttacggataa ccgttgtctg cttttcgttt tttgcatttt ctctcctctt ttctcctagt
    10981 ttttttaacg cgggatggtt gatgaaccgc ggttatgtga aacaaacaat aattataaca
    11041 gacttttcat ttatttcaat ccgtcttatc tgcttttaaa aaagcaaaag cttaaacaat
    11101 gtaaacgttt gctaaaaatc gtgggatatg gtataaagta agtgtaaggg gtcataagaa
    11161 ttcccagtaa agcagacgaa gtaggatctg caagaacaga attgttgtga aacttaaata
    11221 aataaaaaag gatgtgggaa tttgagcaac ctcttactag agaacggtct agcaagcagc
    11281 tgaagatcta agtggacatg ccgaaccttg gaacttctcc ttacgtaagt aatggatcat
    11341 gcgcttgcta ggcttttttg tgtttttcgg tcttcggacc tttttcattt tcctagactt
    11401 ctgctataat aaccaagaat taattttgta acagattttt ttgaaaaaac aagtttcttt
    11461 cattcaaaaa atagaaaaag cttgctaatt attggttaac cagcaaacag gagtattaaa
    11521 atatcttgtt ttattgaata gcaggaggaa atcatgaaat tccattatca tatattgatc
    11581 aatccatcgg caggcagcgg aaatggctat aaagtagcag aaagaatttt accggtatta
    11641 aaaaataagc atattgacta tacacttcat tatagtgaat acaaaggaca cgatgctgag
    11701 attgctgaaa ctttggcaaa agaaacattg attccttgga tagaagaaga acagaaaaca
    11761 atcgatactt tccccctttt gatcatcgta ggaggtgacg gcaccttaca tcaggtactt
    11821 gatactttct atcagatgga agtagaattc ccagttgctt atattccagc aggttctgga
    11881 aatgattttg ctcgaggggc aggccttcca aaaaatccca aaaaaggact tcagctgatt
    11941 ttagcagctc aatcaccaga aaaagtccac ataatggctt atgaagaaaa aataagtgaa
    12001 aaaaaaggaa tagctgttaa taatttcggt ataggattag atgcagctat cgtccatgcg
    12061 acaaatcatt cttccacaaa aaagcgattg aacaaataca acttaggatc attttcgtat
    12121 ttattctcta ttctccgtgc tttattcact caaaaaggat ttccaattct ggtagatgca
    12181 ggaggaaaac aattaagttt ttcaaacgca tttttatgta cagcaacgaa gcatcctttt
    12241 tttggcggag gaatcgcgat tgttccaact gctgatgcgt ctaaaccagt cattgatttt
    12301 gtcgtggtcg aacgaatcaa tttctttaaa atcttgtggc tcattctttt acttatacag
    12361 aaaaaacaat tgaaatcgaa atatttccat cactacacaa caaacagatt acgtatcgtt
    12421 tcaacaacac cgcaacatgg tcaagaagat ggagaagaaa tggaaaaacg accttttgat
    12481 atcacaataa ccacaactaa acagttgttt tggtgttaat aaaagaggtt ttgtcagaag
    12541 ctacatctgg aacaccgttt attcggaaaa aaggactgtg acacgacttt tgtcacagtc
    12601 ctttttttac tatgcagtta attctttgcc caattgggtt gccatcgata gtttctttct
    12661 ttacccaaaa taaattggat cattgaaaac accgcagcaa aagcaactaa gacacaacca
    12721 ttgaaccaaa aagattctgc aaatgtttga ttgtaactga gtgtttcact gatcaagtta
    12781 ttattttgaa caaaccaata tgttggtgtg aatgccgcta ttttgctaac catttctggc
    12841 aagtattctg ctggtacaaa caccccaccg ataaagcaac tgcctgtgat aaaaatatct
    12901 ttgatcccac cgctggtttc tgagtttttt accaatgaag tgatacaagc cgaaaagcta
    12961 atgatcggca ataaaaacaa gaaagtattt aaaatatgat accataccgt tatatcccac
    13021 gaggtgtgga tcactaacag aaccattaga agtaagaagc cactgaacaa cagcagcgag
    13081 taactaatca aactaaaggt tactttgcga ttcaagtttc gtttggtaat gggcgcactc
    13141 tggtttcgtt tactgatctc tttgcgatta aacgctagat tgatgacgct gaaaccgcta
    13201 aaaatggata gaaacaaccc ataagacaag aaattaaagg ttgtgcccgt caacagcttt
    13261 ttcatccgct gactatatcc cgcacttagc tcaacttctc cagtaaccga gagtgccatt
    13321 tgtgtctgtt ccatagctgc atcgattgtt ttatcttctt cttgaaacag aatcagtgtt
    13381 tgcaaaaagg tgttcacttg ctgtgtaaca actgttttag aaaaggcatc tgggcgactc
    13441 tgtatcttga tcgtcgccat ctttcctact tcgacttgtt cggtaaagtc tgcaggcaga
    13501 tgtaagataa tgtttacacg attaaaataa agagcatcat cgatttcttt ttgtgaggtt
    13561 ccatccaatg taacgactgt ttccttgtca ttcaaatatt tacgaaggcc atcgactaca
    13621 ggcgactctt cttcactaat caaggcgatt ttcgcatctt gcagagaggt attttcaaca
    13681 tcaatatttt gcgcaaaaaa gaatgtggca acaacagtga taattacacc tatcagtaaa
    13741 ttcgatttat ttgctttaag caatgtccaa atcgttttat aaagcgtcat aacgcacccc
    13801 tctttccatc caagcatttc ctaacgcaaa aaggaaaata aatccgatca accatagaag
    13861 attggtataa aaactagcca aatcagtgta gaaataaagt ttatacaaac tttcgctgat
    13921 caagttgacg agatttaatt gaccaacaat cggaatatga agatcaatcc aatacttcac
    13981 ttgttccgac cccatcatac cagcaaaaaa gctcatcgca atcgtcactg aaatcaagat
    14041 gctatccttt tgcaccagat tcatttttgg tatcaaatta ccaaccaatg tacctaacaa
    14101 aatcgcacac aacgacccca gagcggtaac aatcatcaac cattgccaac gttcaccaaa
    14161 gtctacttga tagataaaac gaaagacagc taacataata taaatctctg tcaaaacaat
    14221 cgtaaagctt gctgccaaat tagcgattga aactaacgat tgctttctag gaatcaagga
    14281 caagcgaata ccatttgacg attgatttgc ttgctgatcc tgtacattgc ggacccccca
    14341 catcgtcccg tagagaatcg ccattccaat cagagtgaag aaataaaaac ttttgaaact
    14401 catattacga cctgcatgaa cttcttgaaa agatacttct tgttcaaaaa cagtcatgat
    14461 gggcgcgaga tcaacgttct ccacttctgc cactttactc gaaattatac caatacgctg
    14521 taaaaattga tccatgacgt ttttcatcaa cgtctgactc attcctgctt gacccacatg
    14581 gagcgaaaca gatgaaccat caatgagata aaaaccagcc aaatcatctg catttagctt
    14641 ttcattcgct tctacttccg atagttcctg tacttcaaat aatggtttat cattgacttc
    14701 gacttgttct aagactgtgg taaaattttc cgaaagcgct gtttgatccg ctttgattac
    14761 aattccagta ttaatcgttt caagattgcc accttgatca atctcgccaa aggccgccat
    14821 aaacatcaat cctaaaagaa ttggaaaggc caatgtccaa aacaacatgg atttatttcg
    14881 cagcagtatt tttgtgcgat atttataaaa atgccaaaac attatttccc ctcctctagt
    14941 ctctcaaatc cttgccagta atctctaaaa agacatcatt caaggacgct tctttggttg
    15001 ctatttttcc gtaactgatc ttttcttctt gtaagattgt aagaatcggc aacaatactg
    15061 tatttagttc agtagttgtt acttggagct gacctttttt ataagcgatt ccatcagaag
    15121 ctattgttcg ctgaatcgct gacaacacat tttctgggag taatgggatg tcgatcgtca
    15181 aacgatccgc cgtccgtacc atatctttta gagattcttt ggttccttta gcaatcacct
    15241 gtccttgatc catgatcacg atctggtcgc aaagaatttc tacttcttcc atgtaatgtg
    15301 ttgtatagac aatggttgct ccttgtcgat tcagctcctt gatactttct aaaattttat
    15361 tccgactttg ggggtctaca gctactgtcg gctcatctaa aaaaattaac cgcggcttgt
    15421 gggcaatccc acatgcgatg ttcaaccgac gtttcaagcc accactaagt tctcctggac
    15481 gaaacgaaac atatttttct aatcccacta attgaatcac ctcttcaatc aaggctttcc
    15541 ttttctcttt ttcggaaaca tataaaccgc aaaaataatc gatattttct tgcacactta
    15601 gttcgtcaaa gaccgcaacg tcttgaggaa cgaccccaat cattgccttg acagcataat
    15661 tttcaggagt cattgttgtc ccgaacaatt taatggttcc tttgtcataa tttaacaaag
    15721 aaagcataca gttgatggca gtcgatttcc cactgccgtt tggacctaac agacctaaga
    15781 cttctccttc ttgtacttgc agatcaaaat gattcaatgc tacaaaatct ccatagcgtt
    15841 tgactaattt atcaatttcg ataatcatca tgaaaaactc cttccaaatt tcttgttgat
    15901 ctgactataa taaagtgcaa gaaaagaaac tagtgacgat tggctaaacc acacatgaca
    15961 tttgtcacaa tgaaggagtc tgctatgcat aaatctcggc tactcaacga aactagcttt
    16021 ctactggtta tctcattgct tttgctggta agtcaaggat tcgttgctat gcaagttatc
    16081 tatttattga tcgccgtttt attcactggt gtcagttatt tactgcctac aaagccaaat
    16141 tggattttcc aagttattct atttctttta tgtgcctttt tacctgatct tgtcctgttt
    16201 ctgccagcga cgatgcgagt gatcgcccct gaagaaagcc accttgatta cttgtttttg
    16261 ttaggttttt tgttgatttc gacggttggt aatcatcccc ccatcaaggt cgcctttgtc
    16321 gtaattttgc tgtttttttc cttttactta cgaaaaaaag atcaacgaac gaccgatctt
    16381 gagaaaaagt acattgtctc caaagatact cattgggaaa aacaacaaga gttatcggaa
    16441 caaaataaag cattggccct gtcacaagaa acacaattag ccttgcaaat tgtggaagaa
    16501 cggaaccgaa ttgcccgaga catccatgac aatgtcggtc atctgctgtc aagtgcgatt
    16561 ttacaaattg gtgcgcttga aatgatcaat caagaaccaa aactaaaaga accattagaa
    16621 aatttaagtg ccaccgttca cactgggatg gatcggattc gtcaaagtgt ccatgacctc
    16681 catgagacat cgatctcttt tcaacactcc ttagagtttc tgatcgctga ttttccttct
    16741 tctgttacga ttgaaggaaa cttgtttgaa ggattgaatg aaacgcagca aaactgcttc
    16801 ttaatggtca tcaaagaagc cttaaccaac agtatcaaac atagtcatgc caaaaccgtt
    16861 gttttacatt ttcgaacgtt gccggccttt tatcgcttgc aaatcacgaa tgatggcacc
    16921 agcccacaaa aaaattctgc tcccggtatt ggtttgaaaa cgatgcgtca acgtgttcaa
    16981 gaacaaaagg gacaagtcca tattttccaa gaaaaccagc aatttcagtt aacgatcatt
    17041 ttaccaaggg agggacacca atgataacag tagtcattat tgatgatgat ccatttgtga
    17101 cgaaatcgtt acaaaccatt ttagaaagca cgaaagagat ccgtgtgtta ggcattggtc
    17161 attgtgccaa ggatgcgcta gtcttatacg aaacccatcg tcccgatgtt ttgctgacgg
    17221 acatccgcat gcctaaacaa acgggcatcg atgctgccaa agaaattttg gctaaatttc
    17281 ccaaagccat ccttttgctt ttgacgacat tcaaagatga agaatacatc cgcgaagcat
    17341 tttccatcgg tgtcaaaggg tatttaatca aacagaactt gcaagcgatt attccttctg
    17401 tcaaatccgc ttataatgga caggccgtat ttggtaatga aatcatcgag actttcactc
    17461 aaatgatgaa gaataaaccg acgattgata gtcatgctta tgcttctttt agtgaacgtg
    17521 agcttgcaat catcaaagaa gtagctgccg ggaaaaacaa taaagaaatt gcagatgcct
    17581 tgtacttgag tgacggcact gttcgcaatt acatcagcca attactagaa aagctagatt
    17641 tacgggatcg cacgcaattg gctatctatt tttatcagca tttgcaataa gtcttatcta
    17701 acacaaaaaa acctgaatga tgctccttcg catcattcag gtttttttca catcttctat
    17761 tcaattgtcc cgcaaaccat ttcctcacga ttgaaagaat caaggattcg cagggctgcc
    17821 aggattcgtt ggattgttcg gcgtgttagg cggaaaaata ggcgccttgt ctaacgtttt
    17881 ttctagtttt gattcttcac gatcgtctcg ttctacatca ggactttcat tcaatttgaa
    17941 ttctttttcc atctcatcta actttttaaa gtcattgcca gattcttttg ctaatttcgc
    18001 taatttatct tcggtttctt tagccataaa gtaacgcccc ccttttgatt tcagcttagc
    18061 atatcacact gaaaaaacaa aagaaaacgc taaccaacga tcatttttag ctatttctca
    18121 tctttaaaat caagcatttt ttgccggtat aaaatcgtag ggagaactgt tttccatacc
    18181 aatcatcgga tctactaact ggttatcgat cacttctgct gtaagaacga aatctttaga
    18241 aacagcaggt tctacctctt ctttcttttc ttctccaaca aatgaagaaa acagatctgg
    18301 ttccactgtt tccattactt ggtttttcgt ttcattcgtc ccactgtcat cttctacagg
    18361 tagcttttct tttacaaccc gtggctcttt tgtatagttc ccatcttcaa atggatcatt
    18421 tccgaccaaa gaatcttcat aagctgctag tttggtccgg agagtgatat tcattttatc
    18481 attatccatg atccttgatt tcaacgtagt catccggctt gctgattcat tcgctacaca
    18541 agtgacatag gcttgctctt cccctaacaa aatcaacagt tccttactgc gagtcactgc
    18601 cgtgtagagc aaattacgct gaagcatccg ctgatattga tggaccatgg gcaaaataac
    18661 catcttgaat tcactgcctt gtgatttatg gattgagcaa caataagaaa gagtgatttt
    18721 attccattcg tttcttttat aagtgacctc atttgcatca aactggataa ctaattcatc
    18781 cactttatct tcagaatctt ttgccaagat gatacccgtg atttctccca tatctccatt
    18841 gaatacattc aattcgggag tattgactaa ttggaggact ttgtctccta tccgataaac
    18901 ggtgtcgttc caatgtactt ccttttttcc aggtttccct ggattgaata tctcctgcat
    18961 cattttattt aacgcatcga tccctgcagg tccccgatac attggtgcta atacttggat
    19021 atcttgtgca cggaatccct tatttttcgc tttttccaca attttagaga tcaagggttc
    19081 aatttgataa gcatcacttc ggaaatagga acgatctttt tgattctttg tgaaatcttt
    19141 tggcagacgt ccttctttga tctcatgggc aagaggaata atactagaac catcaccttg
    19201 ccgataaatc tgattgagtt ccattttggg aatttgttcg atttccaaaa gatcatggag
    19261 tacttgacca ggaccgacag agggaagctg atctttgtct cctactaaga taacttgcat
    19321 attcgtcgga atcgctttga ataatgtgtt agccagccat gtatcgacca tagacatctc
    19381 atcaacaatc aaaagtccgc cttctaattc tttcgtactg actgaaggtg ttttttcccg
    19441 tccattcagc cccagaagac gatggatcgt actggcaggc agacctgtcg tttcgttcat
    19501 tcgtttagct gctcggccag ttggtgctgc aagtagaata ggaaaaattt cttgggtata
    19561 ttttgaagga tccaattcca gtccgttcaa ctctgcaaaa agattgacga ttccgttgat
    19621 cacagtagtt ttccccgtac ctggtcctcc tgttaaaata aatagagggg aacggattgc
    19681 ttcagcgata gcttgttctt gcgaaggtcc atactgtatg ccgaatattt tttcgatacg
    19741 ccgaatattc ttctgcactt ctttttcagg ataatggatt tcttttttac gactgagaag
    19801 gcgctggatc gaattaccga tcccccattc agaaaagtac aaactgtttt cgtaaagatt
    19861 agtctcttct tgttgtatct ttccttcttc aacaagttgg ataattacag tagcaacctg
    19921 atcaggctgg atttcaattg ggcgacttgt ttctaaaata cggatcgttt gctgaagcaa
    19981 tgtctccgcc ggtacgtatg tatctcctgt ttgaactgca tgctgaaaaa tctgatgcaa
    20041 gatagctgct cgaattcttc tcggtgaatc tgctgcaata ccgatttgtt cggctagatt
    20101 atctgcacgt ttgaacccga ttccttctat gtcttcgact agctggtacg gattttcttc
    20161 gatgatatcc aaagactcgt tcttataggc ctggtagata ctgaaagcta actgactacc
    20221 gaacccgtaa cgattcagtc ccatgatcac ttgatccatc ccgtggttta gccgaatcgt
    20281 ctcagcaagc atttctcttt ttggcttcgt caaaccggag atttgtttta ataccgaagg
    20341 atcagcaatg attttttcga tagcatcttc tcccagcaat tctacaattt tttctgctgt
    20401 tttcttcccg attcctggga atttttcgct ggaaagatac gctacgatcc catttgcagt
    20461 tgttggcttt tcttgctcat atctttcgag tttaagctgc cttccgtatt taggatgatc
    20521 cactaattct ccataaaaac gataagtctc attttcttga atatcgccga aacttccggt
    20581 gactacaatc tctttttcac ggtaatcagc tgtggtttca ctgatgtgta ccaaaagcac
    20641 tttgtaaaaa ttactaggat tttgaaaaaa aatcgcggca actgtaccaa cgaaataagg
    20701 catttcttct ggctgcatcg gaagccgcct ccttcttcta tagtaaaggt tctggtgctg
    20761 tttcagttcc taaaaaatct gtttggttcc atactttcag ttcatatggc aataatctgc
    20821 aaggctcttc agtctctaaa atcgtcaaac tactattgaa caatccaccc atttcacgca
    20881 actcacttag ctcttttcct gtcatccatt gaatggctgc agttaaagaa gctccatgtc
    20941 ctacgaataa aagtgggcca tctttatgtc gggcaaccgc atctgctaca acagtttcga
    21001 tacgtgtgat tgccgattca atcgtttctc cgtgaaaagg agaaggatca tacagatcta
    21061 aatgattacg caaattcggc agattatccg gatatttctg gtacatttca tcgatcgact
    21121 gaccttctaa agtacccagc cctagttctc ttagcttatc tgtataaaaa atctctaccg
    21181 gacgagcaag ctctttgttg ataccttctg ctgtatcacg tgctcgcttt gctgtactgg
    21241 aataaattgc tttaaaagga acatatttta cctttttccc aaatgctttg atttcttcgt
    21301 aactttgtgg caaaagcgga gaatcgccat tgctcccttg aaaacgtctt tcctgattcc
    21361 attgtgtctt cccatgtcgg gtaaaatata gttccatacg cagcaaactc ctgtctttct
    21421 tttattttac tctataataa actgtctaat ccagcttgtc attttcatag tgatgcgtca
    21481 attctaaatt agggaatcct tgctggcgaa gtgcttcata cactatcatt gcagctgtat
    21541 tcgataaatt caatgagcgg acatgctcat cattcatagg gatgcgtaaa cacttttctt
    21601 cgttttcacg cataaatgtt tctggcaaac cggttgtttc ttttccaaat aaaaagaagt
    21661 gctcttctcc atcagcaaaa ttttcgtcac tatatacttt atgggcaaat tttgagatca
    21721 aatgtagttt acgattacct aaaaatgtta aaaaagcttc taaattactg tggtaagtaa
    21781 tatttacatc attccaataa tccaaccctg cccgttttag atgtttgtca tcagttgaaa
    21841 aacctagtgg ctcgattaaa tgaagcggag tattcgtggc tgcacacgta cgggcaatat
    21901 ttccagtgtt tgcagggatt aatggttcaa ataaaacgat atgattcatc aggatcattc
    21961 ctctcatatt tatgttcgtt tctattttct gacaatttga tttttgcata aaaaaaaacg
    22021 tatcaactcg gtgtcagtca ctgcgagtcg ttacgttagt gaagctcttc tcactaactt
    22081 ttatcagaac aggaacctga taaaaaccaa tgaaaaaaca acttgttgct aatataacac
    22141 cctcaacttt tttttgcaac ctctactcat taaaaactgc tagaaaaacg ttttctctta
    22201 gttcctttta ataattctat gtcaattgta atcttcttca aaggattctt atataagtct
    22261 gctttgattc gctcttctac ctgccattct aaaggtgaca tggccaaaag atctttttga
    22321 ttttcctctg gtatctcaaa ttcataggtt acacgctgac gttcagttaa tttcattgct
    22381 tcagcaaact tggctactac acgttcattg gaataactct gtttttcagg ttgattcgga
    22441 taaaaagcct gacgtagttc ctttaaataa ttttcttgtg gcaccacctt caacacttct
    22501 ccatcttctg agagtacacg ttggaattct tggtaatgag aaggcgaaaa gatatttaaa
    22561 accgcgttga atgtttgatc agcaaacggc aaattggtca aatcagctac acaccaaaat
    22621 gcttcggcag attgttctgt agctgcgtag actccttctt ttgaaatatc aaatccaaca
    22681 gcattttgaa tctttttcaa ttttgaaagt tcattcaaga agctaccttc tccgcagcca
    22741 acatctaata gcgagacttc ttcaggtaaa tgctgcgcaa tagtctcaat aacgggctga
    22801 tacatgccag attggatcat tctacgcctt ggaacgaaca ttccttgatc gtattctgtt
    22861 ttaaccgcat gggataaaaa ataaagtgtt ccttttttgg aaaggtcaaa acggtgatta
    22921 tttttgcata tcaagccatt atcagacttt tttacttctt cttggcaaac cggacagcgg
    22981 aacagctgat gattttctgc caaaaactgg cgtcctcggt caattttttt taacatagtt
    23041 ccccctcatt tctgttttat cttaccgtta gatgctcact ttggcaactg ctaaaaatat
    23101 gatacaatgc ctagaagaaa gtgaaagata aaggagaaga ttagatgatc aaagaatttt
    23161 gcgctgaaaa ctacacatct attcctctag caattgctag aggagccgat cggatcgaat
    23221 tgtgtgacaa cttagcggtc ggtggcacaa ccccgagtac tggtgtgatc gaagaaacgt
    23281 taagttatgc tggggaaaaa gatatccccg taatgacgat tattcgtcct agagggggcg
    23341 acttcgtcta taacgatatc gaattgaaaa tcatgcatac tgatttgatt gaagcaaaga
    23401 aattagggac ggatggcgta gtatttggtt gtcttactcc ttcaggctgg ctagacgaag
    23461 aggccttaga actattgatc gaaacagcag aagggttgca gatcaccttc catatggctt
    23521 ttgacagtat tcctgaagat cggcaattcg aagcaatcga ttggctggta gaacatggtg
    23581 ttgaccgtat cttgactcat ggcggtcctg ctgacaaaac tattgtagaa aatttcccac
    23641 ggcttaaaga attgattgcc tatacagatg gccgcttaat cattttgcct ggtggtggtg
    23701 tcactgcaga gaatgcagca catgtagcta aagaattgaa cgtaagcgaa gtacacggaa
    23761 ccaaaatcgt ggatcttcag ttataatctt ataaacaaaa aaacatttgc aacaggcata
    23821 atgcttattg caaatgtttt tgttttttta cataaaatag cccataaata aagaagcaat
    23881 attgaaataa atcagtacac tcgtcaaatc gctcaaagtc gtgataaagg gaccgcttgc
    23941 tactgctgga tcaaatccta gacgatccat tagcatcggg attaaactac ctgcaagatt
    24001 cgccactgtg attgcaaata gcatagccat ccctatgaca aaccccaaga taaaattatg
    24061 tttccaaaaa cctacgatta gaaaaatcgt gatccccgta acagctcctg tgacaacgcc
    24121 ggtcaagact tcagccaaaa caagtcgaac aaatccatga tctttctcat cagaaatcgc
    24181 aagtcgacga acagccacag ctagcgactg ggttccagca ttaccggcag ttcctgtaat
    24241 cagcgaaatg aagactgcta aaatactcgc ttcacttacc aagtcttcat agtgactgat
    24301 taaagaagcg gtcgacatac ctaaaaacaa cagagtgatc agccaaggca aacgtcgaga
    24361 cgctgccttt actggatttt cattaatttc ttccacattg accccggcaa gtcctgaata
    24421 atcgctagca gcttcatcat caataacgtc gatgatatca tcgactgtga cgattcctaa
    24481 caaatgatca tcataatcgg taacaggaag agctaagaag tcataatctc taaatgtttg
    24541 tgccacatct tcttggtcgt cgcctacatg aactgaaagc actcgttcgc tcatcagatc
    24601 agaaatcatt gcgtcgtcat cattcacgat taggtcgcgc agagaaataa cccctactag
    24661 ctgaccttct tgattaacga catagatgta atagattgtt tcagctacat ctgcttcgtt
    24721 cttcagcacg tacatcgcag agcgaacagt ttgattggct acgatcgaaa caaattcagt
    24781 tgtcatgatc gcgccagccg tttcatcctc gtaatggaga agttccttga tttcactggc
    24841 atcgtctgcc gacatcaaac ttaaatattt agcaatttgc tttttatcca gcgtattaag
    24901 caagtcaaca gcattatctg tatacatctc agaaagcata tcagctgcat agctaggacg
    24961 catttcatct aggtattctt tcatatgttc gttgtcttct tcaatcacat cgaacatatc
    25021 cgctaattct ttaggcgaca gataggaata gatcagctgc ctgttctctt ctgtaagaga
    25081 ttggtagaat tgcccctgct catagatatg catctctaaa aaactgtttc tgaatgcctg
    25141 aatattattt tcccttaaat cttgagtcaa ctgggcaaat ctttcctcta attcttgatt
    25201 ttcatccaaa ccaatctcac ctcgccttat tcttcaaacc gtctcacaac tgcctccatg
    25261 tctgcggcta aaggctgctt gaactccagc aactcttctg taaatggatg gtaaaaacgc
    25321 agatcataac aatgaagggc ttgtcttttt attcccagat ccattcgccc gccatacata
    25381 tcatcaccga gcagggcaca gccaattgcg gaaaaatgaa ctcttatttg atgtgtcctt
    25441 cctgtatgca gctggatatc aactaacgcg atttctgtta gtcgcttctc tatccagtac
    25501 tcagtctgtg ccgaacgtcc ttcatcagag accattcgct tcaatagcga agaataatct
    25561 cgggcgatcg gcaaatcgat atgtccatgt gccgataaat ctgaaagcct tccactgact
    25621 aaggcctgat attttttcac aaacttcttt tcacgaagtt gcatatctaa ttttgcgtgc
    25681 gcaaatccat gctttgcaaa aagcatcaag ccagatgtat cccgatctag tcgcgtcacc
    25741 acatggatta cttggttttc gtaaccttgt tttttataat aagcctttac acgattagcc
    25801 attgtcccat ttggatggta ttgggcagga atagacgaaa cgcctgctgg tttatttact
    25861 accagaacgt gttcatcttc atacacgata tcgatcggtg tttcatccaa aagtacggtt
    25921 tcatgttctc cttcagcagg aatcacaatg gttaccttat catccttagc tagagaaaac
    25981 aagacatttt ctacttgatc attaactttg atttgaccgc cttgaaattt tattttcgct
    26041 aacagaccct ttgagatccc tttttctttt aaaaaatatt ttacttgctg agaatgatct
    26101 ttctcataat cccatgtaaa ctgcatatca atcctcacta ataaaggcat ctttcacacg
    26161 atgccaaaaa tgcatatgtc gataagaagc aaaatggatc cgttcttctg ctattcgata
    26221 ataaattgag cggatatttg cttttgcgac attcaattga tcaaccgtta caagataatc
    26281 ttctgtattt tccaatttta tttctagcca ttcatcatgg gcaatcacga tcggagaacc
    26341 caaagtacga aacactcgat tattcagtga agcaatctct gccaactgaa aggcattgat
    26401 actaggatgg atcacagcac cgccgacact tttattatat gctgtcgaac cagtaggcgt
    26461 agaaatcgtc aatccatctc ctctaaaact ttcaaacagc tcgtttttga tgtatacatc
    26521 ggctaccatc gtacgattgg cccgtttaat cgttgattca ttcagtgcta aaaaatgctg
    26581 gtccggtgtt tcatccaaat aactgatccg aacatccagc aagggataac taacactttg
    26641 ttcccggttc gttcgtaagc tgtctactag ttcttccagc tcgtaatccc gccaatccgt
    26701 gtaaaaccct aaatgacctg tatgcacgcc caagaaacgc acatcattca gacaatgact
    26761 gtagtgatgg aacgccgaca ataatgtgcc gtctccgccg actgagatga ccaattctgg
    26821 ctcatgatca tctcgttgaa tccctgcttg ttctaaaagt gcgttcaaac gttctgtcac
    26881 ttctatagtc tttgcttctt tattatgaac gatcgctact ttcatcccct gcctcctctc
    26941 tttcgctttc tttcttcaaa agcgttcgat agtagacatc atctgatttt cctcttccat
    27001 gggagaataa ccgctgtgct tcttggattt cttcacggat actggacatc tcttcatcca
    27061 actgataggc agcttctgcc gcacgctgaa gtcgttcact catttcttct ggaaaaacgc
    27121 cttgatattt ataattcagc gaatgctcaa tcgttgccca gaaattcatc gcaagagtcc
    27181 gaatctggat ttccgccaaa attttcttct caccgctgat cagctgtaca ggatactcga
    27241 tcaccagatg ataagaacgg tagccacttg cttttttatt tgtgatgtaa tctcgttctt
    27301 ggagaacttt catgtctttt cttttacgga tgatctcaac aacttgatgg atatcttcta
    27361 caaactgaca catgatcctt aacccggcaa tatcagacat ttcttcttct aaacgtccca
    27421 ttggaatatg ccgtaattgt gattttgtta caatactatc gactggcttg actctcccag
    27481 tgacaaattc aatcgggaca tgtcgatttt gttcacggaa ctgtttgcgg atcccccgca
    27541 gtttcacttt caattctgat acagtttgtt catatggtgc taaaaatgct tcccaatctc
    27601 gttccatagc tgatacctct acttcattaa cattcattgt ttattctacc atatatgcaa
    27661 agttttttcg tactcttgat ttatgcattg accaaaaaaa gaaaattagg caaaatagac
    27721 aaaaaggagt cgatcaaatg acacaaatgc ttgaaatcga atataaatct atgctgacaa
    27781 agcaagagta cgagatattc atcgctcact atcaattaac agataaagat ttccgtgtac
    27841 agactaatat ttatttcgat accgttgatg aacagctgaa gaaacaaaat tgtggcctac
    27901 ggatccgttt cgttggtcat caagctgaat atacattaaa aacacctgct gaaaaagggc
    27961 gtctcgaaac aacggatacc tttataacag aagaagcaga agcatttatc ttcgaaaaac
    28021 gtctgcctcg ttcaggcgca gtttttcaaa aactttctga tttgaatatc gatcctgctt
    28081 cattaatcca aaccggaaag cttacaacaa aacgagctga attccctatt gaagaaggac
    28141 ttttagctat tgatgaaagc tggggagaca atctacacga ttttgaactg gaactagagg
    28201 taggggatgc atctgtggga aaaattgctt ttataaattt tttaaaacgt ttttctttac
    28261 cttatcgtcc tgctaagaac aagatccaac gtatgcttga agctaaaaat tagaaacctt
    28321 tcattttcac aaggcacttg agttcatttt tttacttttt tctgttaagt tataggatgt
    28381 gaaagaatct agtcactagt tgtatagaat ctattttggg ggagattcat atgatcgaaa
    28441 tctatttatt tgttaatcct ttaggggaat actgtttcga aatggaacaa cagttattac
    28501 aatttatcga agaagagtac gggacaccat caaaagaaaa gatgcaattt cgctttcttc
    28561 ctttggtcaa tttgcagaca attggggatg tcatgcaaca aaaaggaatt tctcagaaca
    28621 atcttgagga acgtaatcac ttattctcaa tgacttattc tgcagcattg gactgcaaag
    28681 cggcgcagtt tcaaggaaag aaaaaaggcc gccgtttttt gatcaaattg caagaagcag
    28741 tcggctgtaa tgacatacca tattctcaag aacttgctga atccatattt gaagaaatcg
    28801 gcggcgattt gaatatgttt aaagaagatc gtcagtctga cttcgttaaa gaagtattct
    28861 tttctgatca aaaaattgct cgggaaatgg gcatcacaaa acacccttct gcagtcgttt
    28921 acaattatgc ctgcgaccgt gattttggtg ttttagtaga agtaaaaggt acaagtagcc
    28981 tttggagaat cacagagctg tgtaaaacaa cagataactc atatcaagtt tttaatggtg
    29041 aacatttaca tacaaatgat tctcagttcc attcaagaac tagccattta cacttgcttt
    29101 ctaattaaaa a
//
LOCUS       DAJSMK010000027        27752 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.027, whole genome shotgun sequence.
ACCESSION   DAJSMK010000027 DAJSMK010000000
VERSION     DAJSMK010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.027"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(276..1220)
                     /locus_tag="ON488_001216"
     CDS             complement(276..1220)
                     /locus_tag="ON488_001216"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HCR3231420.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1516..2460)
                     /locus_tag="ON488_001217"
     CDS             complement(1516..2460)
                     /locus_tag="ON488_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231421.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2681..3895
                     /locus_tag="ON488_001218"
     CDS             2681..3895
                     /locus_tag="ON488_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3231422.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AALGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            3917..5932
                     /locus_tag="ON488_001219"
     CDS             3917..5932
                     /locus_tag="ON488_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HCR3231423.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6015..7388)
                     /locus_tag="ON488_001220"
     CDS             complement(6015..7388)
                     /locus_tag="ON488_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCR3231424.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7414..7698)
                     /locus_tag="ON488_001221"
     CDS             complement(7414..7698)
                     /locus_tag="ON488_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3231425.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7700..9715)
                     /locus_tag="ON488_001222"
     CDS             complement(7700..9715)
                     /locus_tag="ON488_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HCR3231426.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(9894..10199)
                     /locus_tag="ON488_001223"
     CDS             complement(9894..10199)
                     /locus_tag="ON488_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HCR3231427.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10288..11319)
                     /locus_tag="ON488_001224"
     CDS             complement(10288..11319)
                     /locus_tag="ON488_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR3231428.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11526..12401
                     /locus_tag="ON488_001225"
     CDS             11526..12401
                     /locus_tag="ON488_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR3231429.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12553..13395)
                     /locus_tag="ON488_001226"
     CDS             complement(12553..13395)
                     /locus_tag="ON488_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCR3231430.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13487..15364)
                     /locus_tag="ON488_001227"
     CDS             complement(13487..15364)
                     /locus_tag="ON488_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCR3231431.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15361..16782)
                     /locus_tag="ON488_001228"
     CDS             complement(15361..16782)
                     /locus_tag="ON488_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCR3231432.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16785..20174)
                     /locus_tag="ON488_001229"
     CDS             complement(16785..20174)
                     /locus_tag="ON488_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HCR3231433.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20431..21822
                     /locus_tag="ON488_001230"
     CDS             20431..21822
                     /locus_tag="ON488_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231434.1"
                     /translation="MEKNIRVLSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(21895..22542)
                     /locus_tag="ON488_001231"
     CDS             complement(21895..22542)
                     /locus_tag="ON488_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HCR3231435.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22550..23236)
                     /locus_tag="ON488_001232"
     CDS             complement(22550..23236)
                     /locus_tag="ON488_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231436.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23242..24315)
                     /locus_tag="ON488_001233"
     CDS             complement(23242..24315)
                     /locus_tag="ON488_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231437.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24537..25211
                     /locus_tag="ON488_001234"
     CDS             24537..25211
                     /locus_tag="ON488_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3231438.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25216..26556
                     /locus_tag="ON488_001235"
     CDS             25216..26556
                     /locus_tag="ON488_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCR3231439.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26705..27691)
                     /locus_tag="ON488_001236"
     CDS             complement(26705..27691)
                     /locus_tag="ON488_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HCR3231440.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8089 a         5249 c         5038 g         9376 t
ORIGIN      
        1 cagttaatca aatatgaacg aattagatat gaatcattgt atttgccgtt gcggaaggat
       61 tttttaatta accacagata aacattgata acgattcgct tattgtaatc aacagattaa
      121 atttcatatg ttcatatgta cggatacatt ttcggaccga ttaattttaa ccattctgtt
      181 tatttgctta cctattagat atcaataaaa aactgcttaa cagctatttc agctgttaag
      241 cagttttagg atttttagtt catattcatt gtttcttata atacagtgtt caatacttct
      301 cttaaagcac ttgttgattt gctgaacatt gctttttctt cttcgttgat tgataattca
      361 acaacttcac gaacaccatt ttcgtcaacg attgatggca cacctgtaaa gatatctttt
      421 tcgtcgtatt caccagttaa ataagcagat acaggcaata cagcttgttc gttattcaag
      481 atagctttta cgatacgtgc agtactcata ccaataccat agtaagttgc ttttttacga
      541 tcaatgatct cataagcagc attacggact ttatcagcaa tcacatctaa ttcatcttgg
      601 gcaatacgat ggtctttttc tacaatttca aacactggtt taccaccgac agttgtatgt
      661 gaccatgcag caacttctga atcaccatgt tcacctaaga tatagccgtg gacgctgcgt
      721 gggtcaactt ttaatttcaa tgcgatttct ttacggaaac gagttgtatc caatgttgtt
      781 ccagtaccga taacacgtga tgttggcaga ccagattcgt tccaagcgat atatgtcaaa
      841 atatctactg ggtttgaagc aacaacgata ataccgtcga atcctgatcc catgatttct
      901 tttacgattt ggcgcatgat tgacgcattt gttttaacta aatctaaacg agattgacca
      961 ggtttttggt tgataccagc tgtgataaca acgatatcag catctttaca ttcttcatag
     1021 ccacctgacc atacagccac attttcatcg ccccaagcca taccatctaa aaggtccaat
     1081 gcttcccctt ctgctttttc ttgattcaca tcgatcaata ctaattcatt agagattcct
     1141 tggttgatca ttgcataagc gatacttgtt ccaacaaaac ctgtaccgac gattactact
     1201 ttacgacttg tttttttcat gaataaacag ctccttttca taactatttg ttactttcat
     1261 gaaaagtata gtcttgttta ttcattttat caacatgtta attataatag ttgttattat
     1321 aatttttgat ggaaacgaat tcctgaatac gcataacaga taaatgacaa atgtttacac
     1381 ctatatcccc tgataataca accaaaagtt tagaactgaa aataaatcca aaaaaattcg
     1441 ctgcaacgat ataataagac agcaatcgca cctaaaacaa ttttccttca tatgctttag
     1501 tgaaagattt tcttcttaat gtttatttct ccattcattg ggagtacatg ttgaatactt
     1561 cttgaataat ttgaataaag aagtcgtttg tttatatccg atacgattag cgatttcttc
     1621 caacgaaaaa ctcgtttctt gaatcagttc caacgcaaag tcgaattttt tctttagaac
     1681 cagttcttga aaggaagcat caaaatacat tttcaattta ttactaagat agaccggatt
     1741 gtagccaaaa tgagctgctg tttcttttaa cgtacaagaa gtaaaatgct tatcgatata
     1801 atctaatact ctaagcatct cattttctgc gcatccatct gctgatgaaa agctttgttg
     1861 ttctaataaa tgagtcaatt cgatcagtaa tagtgatgta tagagattta acgaacggat
     1921 cttatgactg tatgtatcaa aataaatcaa cagcatattt tcaatcaaat gcgtcaaacg
     1981 acttgttttt ccgccgcgaa aatgaatgaa ttgtgtatgt tccccttttt cttttgatgc
     2041 atttatcaaa aaagaagaaa gtagattatt tgtgcttgcc aaatgattca atatctctgt
     2101 agataaggtt tcttctttta ataagatgtt gattaaaata tcctcttgcc ctgtgtattc
     2161 gattctttga gtagcttctt tatcaatgat caccacgtca ctttcttcca tctctatcct
     2221 ttctccatta ataatttgta aacatgtacc gctatacata taattgattt caacaaaatc
     2281 atgtgtatgc tcgggaactt ccgcatatcg acggtgttta ctgatatgaa tatttccctg
     2341 ttgaaataga tcccctcggt ggatttttgg cggtgtctga agatggtaag ctaagtttaa
     2401 atcattgata ttcattcctt gttcacgctg cagagtttcg attgattctt cgttacgcaa
     2461 aaaaaatgtc taattcagct agttccaatt gactccctcc tttttgtaag cggtttcttt
     2521 cgcttattag ttcacgctgt actgctatta tatgcaaagc tatttttggt ttcataaaga
     2581 ctttctatgg ttgggacatg aacttcctgt gattccgcta ttgagagaat aaccacttca
     2641 tactatattt ttgataagcg cttacaaaaa tgaaaggaac atgcttatga ataaaaagat
     2701 gatgaaattt tctctgctgt cagtctctct tattttgact tctgctggtg cagtcacgtc
     2761 tgcaattccc agtatgtcag ctacttatgc cacgcgttct ttatctgctg ttgaattatt
     2821 aacgactgct ccctctttta tggtcactat ttttgttttg attagtagtt ttattgctag
     2881 gaaaatcgga caaaaacaaa ctgtgatcat cggattagtg attgcatcga tttgtggtat
     2941 cctccccctc ttctcacaaa gttacagtat tgtcttagct tcaagagctg cactaggtat
     3001 tggctttgga ttgatcaatt ctttggcagt cagcatgatt gctgcctttt atcacggaga
     3061 tgaacgagcc tctatgattg gttttcaaag tgcatttcaa ggatttggtg cagctttaat
     3121 gacatttgtt gcaggacagc tagtacagtt cggttggcaa tatacctttt tagtctacgc
     3181 catcagctta cctattcttg tcttgtttgt tttgtttgtt cctacacctg aaacaactga
     3241 acttcaatcg catggcacag ccccaacaag acaagtaatc aaaacgaatc ctaaaatgat
     3301 tagttatggt atttttctct tgctggtcat cgtggtatat aatgctgtat cgattaaatt
     3361 agccacagtc ctgacgactt attctctagg aaacgaaact aatgcagcga atatcttaac
     3421 aatcatgcaa ttggcaagta tggctgccgg agtttgtttt ggctggcttc agacaaaagc
     3481 acatcgctat atgcttacac tttctttact actgatggga atcggctttg tattgattgc
     3541 cactgtgata aacctgtatg tgattgggtt tggtgcgatc ctaacaggaa tttctttttc
     3601 gttattcatt ccttacttat tcaaccaagt aagtatccaa gcgcccaagt acgcggagag
     3661 tttcaatact tcaatcttat tggttggcgc taatttaggt actttcattg caccatatgg
     3721 tttgctcttt ctctcttttg cttctcttgg gagtaaaaca cttgctgttt tcgtcaatgg
     3781 cagtatcttg ctgttgatta gcgcgcttat tagccttcta gtagtacaca ggacgaatag
     3841 aaagacagtg ataagagtag atgaagaaat aaaagaacaa ttgacaacaa aataaatttg
     3901 atggaggtcg tgtaaaatga caaatgaaaa acataaagat agatggcttt ggtatcctgg
     3961 agactttgag atccgccatg gactgctaca aaatttccaa cgggaagaac gaggttttga
     4021 ctggccagcg tactggtaca tggatgattg ccatcggaac gtcaagttta agagatatta
     4081 ctttcttgat caaccttcca tgtttaaagt gacgatccaa ggagttgggt atgtagaaat
     4141 taatggacaa aaacatccat gtggaaaatg gctgacttgt ccagctggta aagcaaaaat
     4201 tcgtatcttt gtaggacata catcagggct accagcgatg tttatcgagg gagacgaagt
     4261 aaaatcagat attggctgga cagcaagtaa ttttattgaa gaatatccag ctggctggag
     4321 tccgctttat gtcgatatcg caaaagatcc aaatcaaatc tattatcaaa aagaatgcgt
     4381 ccatccagtc actgaaacgg agattggcgg aggaatctta ttcgattttg ggcgagcagt
     4441 gaatggctgt gtagaactaa tatctctgga tgaccatatc gaatctatca ctctatgtta
     4501 tggagagtcc gatgtagaag ctatggatat cgattattgc tactataagc aaataggaat
     4561 gacaagaaaa atgaaagctc gtaaacgcgc ttttcgctat ttgtttatac cagaggtttc
     4621 tactggaatg gttcaacttc aagtttttca tgaattttta tctctttcga aacaagctgc
     4681 tttttcaagc gattcttctt tactgaatca gatctggtca gtatcagaag aagccttcaa
     4741 gttatgtagt gatttgtttt ttatcgacgg tatcaaacga gatcgctgga tttggtctgg
     4801 agatgcgtat caatcattca tgatcaatca atatcttttt tttgacgagg aaatcaataa
     4861 acgaacgata ttagcattaa gaggacaaaa tgaaatcaag cagcatatga atactatcgt
     4921 tgactattcg atcttgtggt tgattggtat cgaaaaccac tatatgatga cgaaagacta
     4981 tgaattttta cgcatcgtct accctaagat gcaatcatta atgagatact tgatggagca
     5041 aacgaatgaa ttagggttta tttatgggag agcaaaagat tggatattta ttgattggtc
     5101 tgaaatggat aaagaaggaa cgcttgctgc agaacaagtc ttattactga aagcctatca
     5161 ttccatgatc acttgcggag atatcttagc tgaaacatat ggagagaacg aaaattatca
     5221 tactcatctc tatcaagaaa aatatcaact attgaaacaa aacctatttg actacttttg
     5281 ggatgaagaa cttggcgctt ttatcgattg ctatgaatct gggagaagaa atgtgacgcg
     5341 tcatgcgaat attttcgctg ttttattcga ttttgctaac aaagaccaac agcaatcgat
     5401 cttaaagaat gtcttattga atgacactat cacacagatt actactccat atttcaaatt
     5461 ctatgaacaa gatgctttat gcaaactcgg acagacgaat atcgtctacc aaacgattct
     5521 tgattattgg ggagggatgt tatctcatga tgcggtaact ttctgggaag aatacgaccc
     5581 tactcaaaca ggaaatgaaa agtacagtat gtatggagat ccttatggaa aaagcttatg
     5641 ccatgcatgg ggagcaagcc caatctatct tttaggacgc tattttatcg gtttgtatcc
     5701 aacaaagcca ggttatgaag aatttatgat acaacctaat ctagattcat ttgaaacact
     5761 gaattgtacg ctacctatca aagatggaaa gatttcgctt gaaaaaacaa aagataagat
     5821 cgtgattact tctgatagaa caggcggaac agtgaaaatg aatggtaaaa gttatcctct
     5881 tctagcaaaa cagccacttg tcttaacaag ctattcaaaa ataaatgcat aaaacaaaaa
     5941 actgcttgcg acatatcaga agactttaaa tcttcttctg atattgtcca agcaattttt
     6001 attttgaagt ttgcttaatt ctgttcttta gaaacaatgt ttgttctttt tccggcaaaa
     6061 agaaagctag ataatacgac aagtaaaaag aaagcgatga ttccaactgt caaggctatt
     6121 tgaccgtatt ctcctagttt cccaagtaca agtcctggta ctagataatc agtatcggca
     6181 aatgtagaag aagcgatttt aagatctcct aatactggaa ggataaataa tggcagccaa
     6241 ctaatcaata agctattgaa agcagaacct aataccgccc ctcttctacc gccagtcgag
     6301 ttgccgaaga caccagaagc agctccgcag aagaaatgtc ctactacccc aggaatgata
     6361 actgtagttt gcaagcctat catagcaaac atggatagtg ttcctacaaa gaagctaaca
     6421 aaaaagccaa ttaatacagc attaggtgca tatggaaaaa cgataggaac atctaatgct
     6481 ggtttagaat cgggtacgag ttttttagca atcccttgga atgctggaac gatttctgcc
     6541 aacaccattc gaaccccttg aaggacgata acaaacccag ctgtgaatgt tccagcttgg
     6601 atcagtgcaa agattacagc gttgtctcca ttgcttagtt ctctttcaac aaatccagga
     6661 ccagctaaca aagcaagtgc gacatatacg atcgacatca agagcatgat cgatacagta
     6721 gaatctcgca aaaagctgaa acttttagga atctttatgt cctctgtaga acggtctttg
     6781 tttccaaaaa actttccgat ccatccacta gaagcataac cgatatttcc ggtatgccct
     6841 aacgcaactt gattgtttcc agtgatgttc ttcataaacg gttgacaaag agcaggcgta
     6901 atagttaata gtgttccttc gaagaccccg cctaataaga tcatccacaa atttgcagta
     6961 aaccccgcgc ttactaaaat gactgctgtt agacaagaaa cataaagcat tgcttgacct
     7021 gtaagaaaaa tgaatttata tcttgtgaat ctagcaagta aaatattcac gatcatccct
     7081 actagcatga tcaaagcagt aggtgtaccg tattgttgca aagcaatcgc cactactgct
     7141 tcattgctag gaactactcc ttgagtatgc agagctgttt ggaacatcga agcaaaaggg
     7201 gttagtgaat tactgattaa accagcaccg ccgatcagta ctaggaatcc gacaaatgtt
     7261 ttgatagttc cttggatcac ttctgaaaat ttcttcttct gaagaacgag accaagcagt
     7321 gcaatcaaag aaacgaggat ggagggctga ctgacgattg acacaaacaa attcaacaat
     7381 ttatccattg atagttcctc ccttgaatca tttttattct tttgacaaga tcttcgttac
     7441 tttttctttt acttcttcgc tgtcaatgat cgattgcaaa ggtacgagct tttcatcagg
     7501 tatagaagtt agcgtatctt tcaaagaatg ctcaatgaag aaataatcag ccatatcgct
     7561 agatacactt ccaacatccg tatgacttac ttcaaactcg tccacatctg ctccaagatc
     7621 tgcaagtgct tgtttgatgt tcatctctac cataaaactt gttcctaatc cactttgaca
     7681 tactgcaaaa attttcatat cattcgtctc cttttcttat gatcgctaat atttcttctt
     7741 ttgttgatgc gtgtaataaa tcttgaagat tttgtttatt agaaagtagc tttgttaaat
     7801 ttgccaaagc ccgaagatgt gcctcattat cgatagcagc taaacagatg aacaaactaa
     7861 tgggatgggc tggattatca agcagatcca caggttgttg aagtttcagc aaagacatcc
     7921 ctacttcgtt tacgccatct tctggacgag catgaggtaa tgcgatgtga tcgccaatat
     7981 ggataaacgc accatactgc tccacgcgct cgatcatagc tttgatataa ctttcttcta
     8041 ttttattttc tgataatagc ggctgtgcgg caaatgtgat tgcttcttgc cagttttttg
     8101 gttgatccga taattggatc atttcttctg ttaataattc agatagcata ggacgttgat
     8161 cctccttctt ttctaaaagt ttgttcattt tacgatttaa tacttgatag agcttttctt
     8221 cgtctacgcc ttcttttaat tcgatataag gcagtagcgc cgacaacaat tcttgggcag
     8281 aaggcattga aaatcctggt atcagccaat ctctttgtac ttgattgatc agctgatttt
     8341 tttccaagtc agtcatgatt ggatgcagaa catagagaga ctttttctta tcagtaagtg
     8401 tgagaggtac agtagaaaaa ataatatcgt aagaagtttc gtcaacctcg tgtaagcggt
     8461 cagctgaatt agtctctgta aaaaagatca tcgggaataa ttgctgaagt tcacttttta
     8521 agatcaatga agagctaatg ccacttggac agacgatcac ggctcttatt tttctatttc
     8581 tttcttctgc gtccgctttt ctgatctctc cgccaaatag tatagtgaaa aaaccaatct
     8641 cttcttcagg gatgctcttc cctattcgtc tttctaacgg aagtaatgct tttcttgtca
     8701 tttcgtagat ggaagcatat tgatgcttaa tttgatcgat catcacatta ggtaaataaa
     8761 aagaatagga aatacgaaaa taggcaggga ccaagtgata aaagacattc atcaataatt
     8821 cacgaaacga agcaaattct acggccatca ggaattccat gcgatggatg acttctgaag
     8881 aacattccag caaaaaatca agtgcaggct cctggacatc tccttcaacg atcgatgcta
     8941 agcaaagaga gaaaaatata atctccgaat tttgatgttc ggaatagcca aggccagtca
     9001 atacttgtcg actaatgtca gtgactgcaa gagaagccaa cagttcagca tcttttacca
     9061 gttccatgga tgtttttcca attcgaatgg ttgtcaaact caaataataa gctaattcat
     9121 ccattcgatt tggtgcgaat cgaagatctg atagtgaaat cgttttatct agcaaatctc
     9181 taactttggc gtaataatca atggaaaggg ttgcggttaa atacgtgagc ccaaatcttc
     9241 cagcaagtga ctgcatcaaa cgagcagtgc gattttttgc ttctcttctt aatattgctt
     9301 ctgaccctag cagcctaaaa ccagttttcc tagtatacga cagctgacaa tcttccactt
     9361 ctaattcatt tcttatcttt ttgatatctg acaggactgt ccctttagaa acctgaagaa
     9421 aatcttgaaa atgaaaaaca gaaacagacg ttgcagtcga ataaaccatc aaataaagaa
     9481 gatctcttcg ctcttgttcg gtatacacag cttcaaatcg agtaatatcc aaaaattttt
     9541 ctgcccagtc gattgctcgg aatttcttta tacggatacg ggtatcatcc acatattcgg
     9601 caaaaggagt taattgtttg atcgcctcgc ttgtatttac ttcgatgatc tctgctgctt
     9661 tttctagact gatttctctt ggtgttttca ggagataact aattttgtag ttcacagcgc
     9721 tgttcacctc ctacttatat tctagtatgg tagcgctttt aaatcgaggg gtgtttggta
     9781 caacttacag ttggattttt tttacgactg taccgaacga tttctatcga atggatacag
     9841 aaaaaaagca ggtgaccaaa tgtctcctgc ttttatgaat tgatttcgtc cgatcaatga
     9901 tgatcatgtt tattttttga ggtcagttct tcaaattttt ctttgacatc ttcaaccgct
     9961 ttttcgatat ctttttcaaa gtgattgggc tcattaggct ttgtttcctc ttctacagaa
    10021 tttgaaccag ataaagctgt ttctttattt tctgtttcac cagagtttgt gccagctaat
    10081 gattcttctt tgtcttctgt ttcaccagaa ttagttcctg ctaaagccac ttcttcttct
    10141 gttttagggg ccattgaacc tcttaatcgt ttgtgttttt caccgtcata atttgtcatg
    10201 ttggttcctc ctagtagttc tatacttttt catcgtacaa taagacagtt tatgcgtcaa
    10261 aaaacaaacc cgattcttac aaatatgtca tatttttcct tctgattctt gaatgctttt
    10321 gattccttct tccaaaattt tcatttgtaa gattgtttct tcatctttga tgactttttc
    10381 tgcgccatta actaatgtct cgtaaatccc ttcgtagaca cggctgtaat caccaacctc
    10441 ggaaattact ttttcttcat gataactccc ttgttcatct atataggtca atacaccata
    10501 atgttcgggc aaatcgatac caaagtcttc atgatcaggc atgtaaaaca ttttcagatg
    10561 ttcttcttgt cgatcttttg tttgtttcac gaacatccct ttttttccgt aaacgacgaa
    10621 acttggacgt tctttgatgc ggaaataact ggattttatc gaaattttca tatttccata
    10681 gaaaaaatcc agatcgaagt aatcattcat tcgtcctttc cctaaaagtt gacgtacatc
    10741 atagctgata tcatctggtt cgccgaaata agaaagaact tgatctactg tatgacaagc
    10801 atgtccatat aaatagctgt tcgcagtaga aaattcatgc gtattttctg gtacttccgg
    10861 tctgaaataa tcataatgca tttctacttc taaaatatcc cctaattttc cgctttcgat
    10921 tactttttgg actgtcaaga agtcagaatc gaaccgtctg ttttggtaac attggataaa
    10981 tagacctttt tcttttgcta atgcaaataa ctcttctgct tcctttgacg tttctgcaaa
    11041 aggtttctct actagtacat tcttaccatg ttcgagtgcc atttttccat attcataatg
    11101 aaattgacta ggtgtagtga tgacaactaa ttggatctca ggatcatccc aaagatcaga
    11161 cagctgatca gtatattcga tgtcttcgaa tgttttccac actggttcag atggggaaaa
    11221 aatttttttg atattgattt tgttcgtaag ttttcttgaa aaaggcaaat gatagcgatt
    11281 tgtactcttt ccattgccaa gataagcgat tgtaagcatg agtggtgcct ccttttattg
    11341 atgttttcag tatatcctag aaaagcgcag aaagtattta taatagctat tctggtaaaa
    11401 aagttcagaa aaacacttgt tatcattcgg tttggtgaaa ttaatgttca aagtaaggat
    11461 aaaaatcaaa aagatagtag cggaaccaag tgtttatcag taagatagaa tttggaggtc
    11521 agatcatgct tattgaagaa aaactaacaa aacaagagtt gtttaccacg acagagaaac
    11581 ggattgtcga ttacatccgt aggaatatcg aagctgcagt ctacatgacg attgaagaat
    11641 tagcaaaagc tacgtatact tcccattcag ctatcattcg tttatgcaaa aaaatgggat
    11701 tcagcggatt taaagaattc cgtttcgagc tggggcggga agttcatcaa ttgattgctc
    11761 agttcaatca aacgattgat cctaattttc ctttttcaag tgaagatagc actcagcaaa
    11821 ttgcaaagaa aatggcggat ttatcgatcc agtcaataaa aaaagcacaa ttgcagattg
    11881 aacatgaaga tttagatcaa atcggtaaag tattgaacaa ggcacagcga atctttcttt
    11941 ttgcaaaagg tgattctcaa atcacggcaa ggaaattcca gaataaaatg gtcaagttga
    12001 ataagttttt gatcatggct gaagaataca gtgattcttc ttggaatgca gccaatttga
    12061 ctagcgagga ttgcgccatt tttattagct acagcggtcg catccatcat tatgaacgaa
    12121 taatgaccta tttgaagcat gtagaggccc ctaccttgct gattaccgga aatcagcatt
    12181 cagaaatggc caaacaggct gatatgtgtc ttgttatatc gcaggaggaa tatgattttg
    12241 ctaaagtagc gactttctcc tctcaaattg ccttcgatta cgtattaaat acgttattct
    12301 cagtgatata ttctcaaaat tttgaagaga atatccgcaa cttgaaaaac aaacaagaat
    12361 tgatgcaaaa aggccttctt aaagaatatc ggaaaactta agaaaagatc ctcatttagt
    12421 aataagaaag atagtgtttg ataggctctc tttgatatca tcataaaaac aggctgaagt
    12481 tttctttttc aaacctcagc ctgtttgttt acggaacgat tcgaatagat atattataga
    12541 aatgaggaat agctaacttc tgtttcttat tttgaacgat tgacgaaaaa gatatataag
    12601 aaggaggaaa atcagtatac atgcagctaa caatccatac aggaaaaatc gtttgttctc
    12661 ggatactttc tgtacttctt tttgaacttc ttttgcatga taaggaaccc ggtgccctct
    12721 gacaagtaag cgatgactgt tgaccatata aggtgtacaa gttaggagtg tcacgaaatc
    12781 ctgccctttt tcgattctca gatcttttgt atcagtcggt tctaccgtct tgatctgatc
    12841 gacttgataa gcgagtgtcc gtccattgat ttcgatatag aaagaatcac ctaaagtcag
    12901 tttcggtaag tctgtgaaca actttgcttg aggcagtcct cgatggctgg aaataacggc
    12961 atgtgtattt tctccccccg taggataaga cgttccttcc aataatgagg cacctttttc
    13021 tagcagcaca gtattcgttt catcaaaaat tggcaaatgg acattgatct cagggatcgt
    13081 caaaataccg atcgtatgtt tctcaaaata ggttctatcc tttttcgcag gttctttttt
    13141 cttagtaaag ggatctgcac ctggatttcc accttctttt gctaattgct ggtttttctt
    13201 tgtcatgttt tcttggattt tagccatgac ttcttcattt tctttgaccg cttgttgctg
    13261 ataatgagag atgatctgct gatccagata attattcagc gcgtcgctaa caaatggata
    13321 agctagtatc cctattcctg agagaagcaa gaaaagcatc agcagatcta gaagtttcct
    13381 tttctttggt ttcatttgtg ttctccttgt gatgactgtt tgataataaa agaaaaagga
    13441 gcatttgcgt aatccgctgc tcctttttcc aattcttgca aaaagactaa atctgactgt
    13501 gcttgcgtct agcaaagtac agtccagcaa tcagtagaag gactactcct gcaccgatat
    13561 acacatagat tcccttaccg cctgttgaag gaagtgtacc tttgtgttta tttggtattt
    13621 tttcaggaga aatcaactgt cctgctgtta cataagattg ttcatcgata gtaaatgcta
    13681 cacggtttgt taatggaaca tatttttctg gcgctttcgt ttcttccaga tagtacgtgc
    13741 catattttag acctgtcaca tcgattaaac cgttacttgt ggttgtaaaa accgttgctg
    13801 attctttcgc cgatacccag ctgacggctt ttgtggatgg gtcgatcgat aaatatttcg
    13861 ctgtgtcact atcttgatca cgaacgacga attctgctcc agcaagtgtt tggtctgatg
    13921 taacgtcacc atctacttta acaaatcgtt tgcccccagt aacgacatcg actgacggtg
    13981 gtgtttgatc atttgtatgc ccgttatcga catttgcttg gttagaaaat cctttggttg
    14041 gatctgcttt ttcgttcaaa tgcatatagt aaacgaattt caatgtaccg ccaggagtta
    14101 atgaaggaat ataattcgga tcaactgaaa ccgtgaatcc gtctgtttgc tcagtgacag
    14161 aataatttac tgggtcgatt tctttatttc catcatataa ggcataagca tacgttcctg
    14221 aagaatcatt atcaaatgtt aaagcagcgt catgagtatc gataagtttg aatgttgtgt
    14281 acttgttttg cgttccttct ttatcagcga tacctaatgg gatattgaca gaaatctcat
    14341 attgaatttt ttcaccgatt gcgacatctt ttccattcaa ttgaggtgtt gttttatcaa
    14401 ctttagacgt atcatttttg atggtctttt ctactggtgt ttggctattt gccaggatct
    14461 caaaaggcgt gattgtttgc ttttcaatca tttccgcatt atcaggagct tttacttctt
    14521 ctaaattata ttttccaact tctaaatgat taacgatcaa ctggcctttt tcaatagatg
    14581 cctcggcaaa gtcattgttg ccgatgtcat aagaatgacc agtaatgaaa tgtttggctt
    14641 tggtttgatc agttgtccaa gtgtacaatc catctgtgac actttggatg tattttttga
    14701 cgcttggtgt tccttcttct ttagaaataa taaattctgc tccatttagt gcttcgtttt
    14761 cggcagtacc gatttttgta actttcaacg ttccatcatt accgactgta tttttagggt
    14821 agagatggat agtatctagt tcttctgtcc cgtatttata agagccatct gcttgtttga
    14881 tcatctcata tacagggaaa gctaaaacca tgtttgcggc agctgacact ccgtcttttg
    14941 gttcttcttt gatcgtgtag actgcatctt tcccattttg ttttttaggt aaagataaag
    15001 tgacatttcc atcagcatct gtcgttcctg aagcaactgg tgtaccagga gtcaaagact
    15061 ggactgcttg ttttgctgca tccacggacg ctcctttatc tcgttgcgca taaaattctt
    15121 gagtgacgtt ataaactgaa aatgaaatat cggctaatcc ttggtattga tcgaattcgc
    15181 tcatttcttt cccgctgttt tggattaaag gatcgggtaa atcagtcatt ttctttttat
    15241 gaaggatgac ttgagctgct gtctcctctg caaacacttt ttttgcgccg aagctgtttg
    15301 tgagtaatgg taaaataagg aaaaggactc ctaacataac gtttattttt ttatgatttt
    15361 tcattttttc actcctgttc tttttttgat aaacaaccag attgcaaagc ttgcgaatac
    15421 cataccaaca acgcctaaaa gtgtattttt cgtttcgttt gtttttggaa gaaatggacg
    15481 gctattttct tttttattga ctactttcaa tatactgtcc gcctctttat cctcagaaag
    15541 aaaagttgaa atggtaaacg gaatttctgt ttcacttaaa atataaccag aaggtgcttc
    15601 gatctctttt aatcgataac ttcctgtttt caacccggaa attgaaaaag cgccattttt
    15661 atcggaaatc aggtgaagcg catctgattc gttctttgtc cacttgtatc cgttggctgt
    15721 ttgctggagg taatttcctg ctttgttttt aataaggaat actgcgccag ctaatcgttt
    15781 atctggttta tttgtctcga ttttgacaaa ttgcttactc cctgtatata cagagacttt
    15841 ctttgtactg acaccaaaac caaaatccag tgttccgttg ttgttgattt ccttgttcgc
    15901 ctgtgctgta ctgcttagct gcatctgata agaaatggtc agtttttttc cagcatattt
    15961 ttccaacgaa gggatcgaaa ataaaacatc aaatccgtga ggtttcttgt gtatgacaaa
    16021 gccttctgtc agcttttctc cattcgatga aatcgttaaa ctattaggta aaaacgttaa
    16081 tgcttcatcc gcactatctg acaattcgaa cttttgatag tcaaggatat ttacaggaat
    16141 tgtcgtatgc aaggaataag tgattttttc accaatcgta aaatcatttc taggctcttc
    16201 taataccttc tcaaaaggtg gatcagggta gtcgttttct tcatttttag gatacaaatg
    16261 gatagttgaa agtttttgat tgttttgtcc atgtacagga agaacaacta ccatattctc
    16321 tgccttttct ttgacgactt ctggtacttt ggattcaatg aaaagatacg ctttatctct
    16381 tttttcttga tctttagcgg ccagagaaaa agaagcgata ccatcttcgt tgttaagagt
    16441 tgtagttgtt gcttctgcgg taaacatacc ggaagacgca ccgttttttg cgatctctgc
    16501 ttgtgcttct tctaccgttt tgcccttttc ccgtagatgg taaaaagaat ctgtgacatc
    16561 ataaacttgg aatgtgacac catttaatcc tcgatacgtt tgtaataaag ctttttcttg
    16621 tccgtcattt ggatgatttt tcggcagttg cccgtttggg aaaagcaatt tgtgtaaagt
    16681 aatctgaacc atttctgttt ctgtttctgt tgctacctga gtaaaagctg gtttaaatag
    16741 taacaagaag agacacatac taagccaacc aagttttttc atatttagct gccccctctt
    16801 tcttttttca aaaaaagata ccaaatagaa aacgcacaac caatcatccc tactagatag
    16861 attcctaaac ggccaattcc tcccgtttca ggtaatggta cttttgcctg attcgtgatg
    16921 tctaaagaaa tctggttgtt tttggctcct ggtgacagaa cagattcatg atcttgtcca
    16981 tccacttgaa ttgacccatc ttcgtgtata actatagtaa ctggctcttt tagaccttgg
    17041 tatccttctg gtgtaaaagt ttcggtcagc gtataagttc caggttttaa attttcgaat
    17101 agaaaggtat ctgtttcttg tccatctttt ggcgattcta agtccatttc tggtccctgc
    17161 agtctgaatt ttgctccttt taatgtctgt ccgttgtctt cttttttgtg taccgttaga
    17221 tcaaacgctt ttagtcgatt ttgatgagtg agcgtccata cattatttgt catctcggta
    17281 ttttttcccg tgtaaatgat ttttccatat ttatcgattt ggaattcata atttcccggc
    17341 gaagtatcat atccggcagg accagctgtt tcaacgactc gatatttacc aggtgtgagt
    17401 gaatcaaaac tggcaagacc tttttcattc gttgtttggc tgtcaattgg ctgataagta
    17461 ccatttgctt cttttttctg tagggaaaat gctgctcctt taagatttat ctctttgtcc
    17521 gtcccttgca tcgcatactt acgtactgct acaggaactt caacaaaagg attttcaata
    17581 gtcaactgga tcgtatcatc ggaagtagtg actgtttttc catcaatggt taccgtacca
    17641 tcagaagcga tcttgatttc ccaagtagtc tttttgctta atccatgccc ttctggagct
    17701 tttgtttctg tcagcgtata ggtcatttct ttttgcaatt tgacattttc tggaagagaa
    17761 taggttccgt cgccatgatc tgttagtaaa gtatcaatag aatctcctgt taatttgaaa
    17821 acagcgccaa taagatcctt ttcacctgta gaggaatttt tcgttatttt caagtttaac
    17881 ggtgtgaatt gtttagtatt tttccatgtc attgcatcta tttgttgaga atcgtatcct
    17941 ggtacaggta attctttgat tgtttggtaa ctgaatgctt gaccttgatt attgtattga
    18001 ggtagtgata atatctcttg ataactttct ccgctatttg cagataattt gtcaatgtct
    18061 gcacgttccc acgtatttgt tgtatcttta gctggtttaa tgattcgaat atatccgttt
    18121 ttccaagctg cagcatttgt cgtatgttcc cgttgaatct caaaagtaac ttgatctgga
    18181 cgatcagcta gattgttgtc aaattcttcc cataactttt tgatgtgaag actgactccg
    18241 ggagctttag cagatggtat accgaattca gctaattcat tggtatcaat gtttggctgg
    18301 aaagttgtcc tgccgttcat ttgataccag aaatttggat ggaagtcctc attttctgtt
    18361 tggattctca cttggtaatg gatttggatt tcttggtctt ttcctaaata gatctgattg
    18421 ctcttgatgg tatttccttc tatggaaata gatggagtga ccgttgtagg acttgtcccc
    18481 acactcttga ctgaaagtgt accaggctga taaatgaatg gttctgcgat tggatcattt
    18541 atttgtccat tgcttacagt tgctgagatc tgtacagctt ttttggctag gtattcagag
    18601 atatctgttg catgatcagc tgattcatag taaagatcgc ctttttcatc tgatgaaacc
    18661 atttgtcgca tacgagactc tacttctgct tttgagagac cagctgccgg atcgctttga
    18721 agttggatgc caagaccatg tatttcgatt cctcgttctt tgagtgccat cgcttctccg
    18781 atggttgcga taaacgtact gtcgattctt ctggatagat tgttttggtc aggtgcatca
    18841 tagattcttg agattagaga agtatttccc ggccgatctt gcgtattaga aaactgagtt
    18901 ccgtaataat tgctgcttga ttgtgcgtgt acccgctgta ctttatagga aaatgttggt
    18961 acaccatccg tcagcaaaac gatcactttt ttatgtccat ttggaacgga tagcatgctt
    19021 cctgcatctc ttagtgcttt ttgtgtaaaa gtaccaccat ttgtccgtga aggtgtaatg
    19081 gattttactt gatttttcac tgaatcaaat gaacccatct gtactgcacc gttactgtag
    19141 ctatatcctt cgcttgagta gccgacatat cccatattga ttttgtctgt gataccgcta
    19201 tctgctaaag tatcgacaaa acgatcgaca ccaatcttta cttcaccgat ccgattattg
    19261 tcgttcatac ttcctgacca gtctacgacc aatacgagat caagaggcgt gatatctttt
    19321 tgtacatttc cacgagcatt caaataaaca tcaaacaatc cgggtgtact tgtttccttt
    19381 gcatactttc gtatcgcata gtctgcttga ttaccggttc ctccatattc gatatacgaa
    19441 tgggtccgat cattaggatc tccattccaa gaatttatac catcccattg atttgttccg
    19501 tttttattgc cttgatgatc aagaacattt gtatttcctg taggttgcca actggcttta
    19561 ggataagtgc cctgatcatc tgttgtatat tctgtaggaa tcgtttgatt agatggcaca
    19621 ctcacagctg gcaaggataa tgtaggcaat gtaaatgggc tgacagaatt ttcgttttct
    19681 tttgatgatt cttcttctat ttcgtctggc tttggtactg acacatctgt atctttctta
    19741 ttttctgtct catcaataat gtcatattct ttattatcga cgatcagctt gtttgcctgg
    19801 ctgtggtaaa gtgctggatc gattggaaaa ctcagatcga tagtttgttt agtgtttgat
    19861 gagatttcca acgtaatttt cccgctattt acctgataag catagccatc tccttctttt
    19921 ctttccacat cacttaagta attttcgact agaccaattt ctttttctat cttttcagca
    19981 ctggtgttat tcgcatttag cttgatgttc agtgcttttt ttccagactg atccgaaatg
    20041 acttcagctg aaattgtttc taaaactgtt ggatcatctg tagtgtctgc tattgcagat
    20101 aatggcacaa agtttgataa actcaatatt atcagcatga aaataacttt cagtttcttc
    20161 cctgtggtcg tcatttttcc cctccttttt ctttttttct gttttgacgt gaatagtgaa
    20221 aattattaaa ataaacaggc gttacataat tttatttatt ttaatatgat aattattata
    20281 cgaagggcgc taaagggaat cacaccaatt ttcataccaa ttggtttcat ttatgaagtt
    20341 gattccttcg attaatgagc gtttcattga aagaaaaggg ttgagggaga aaaacatatg
    20401 atcaggttgt tggaacgaaa ctatagaaag atggaaaaaa acattcgagt tctgtccatt
    20461 tctgacaagt ggatgactaa aaaagaactt gccaaacgaa ttggtagttc agaatctaca
    20521 tttgtaaggt atatcgaaga gatcaaaatc cgctggggaa cggatgtaac gattcaatct
    20581 tcacaaaaat tggggtatcg tcttgaacat ttgaatgtac cagcttattt aaatgttctg
    20641 atggaaatgt cgcaaagttc tacaaacagt cgtttattaa atgagattat tgtcaatccg
    20701 ggtaaaacga ttgagtatta ttgtgaaaaa atttccatca gccggtcttc ttttacacgt
    20761 aagttgaaac aatgcaatca aattttagaa agctatttat taaaagtgat cgttgaccaa
    20821 ggttttcagt taactagcct taaaagtgag ctccagttgc gtatctttgt tacctttttc
    20881 tttttaagtt actacggaag acgcacgttg ccatttccaa tcgaaaaaaa gaagatcaaa
    20941 gaaattatgg tcaagaataa ttgtcagatg aatttgtttc aggaagaaag cccatatgag
    21001 caatctttct ttattatgta ttttgttgtg catctcatga gagaatccca aggaactcca
    21061 tttgaatgga aagctggaga ctcttatgta cagttgataa atatcgataa aaaagacttc
    21121 ttaatcttga aaaatctctt aggaaaattg aagtacagca gctatataaa agtagtgaac
    21181 tattttgtca atacgatttt ttcagaattt tcggagaaag aaaaaaatga aatcagtgag
    21241 cagatacgaa aaaatatgtc ctactgttcg ttttcatccg ctgattgcaa agaaaaaaac
    21301 gaagaatatg ttgttcaatt attaacgcaa atttattttt tctcccgtat tttcccatac
    21361 gatacgactc atttgacgat ccgtgcaact tactttgcac agcagatgca acaccgccag
    21421 atacgtctat atgctggatt tcgtgcagaa cttcaatttt attccactct actgaatcag
    21481 aatctgattt attatttatc tagctatatc ttttggatgc ttatcggtaa tcctgaaatt
    21541 caccattata cttctgataa aaaaatactg attatcagcg acttaagtct tcgacatagt
    21601 caatatattg aagaatatat cagtgatatt cttgctgtgc ataaaattca ctctgagaca
    21661 actgctatta ctgaagatca gctgtcgaaa tacaatcttc tcgagtatga tctgatcgtt
    21721 acgaatcaac ccattttgaa tgcccatgtt cctcatatat tgattgatga tagtgtgtca
    21781 ttcgcaaatg aagaagaact catccgctta ttcgagttat gaataatcaa aaaacagcta
    21841 tgtataaacc accctgataa aaatttcagg acaaatacac atagctgttt ctttttattg
    21901 tattccttca gcaatccaac gagatttata gcgaaagtct tttaacaact cttcttttgt
    21961 ccaattattt gcaatgagat ccgtcaaagt gttcattacg agggtcatgg aaaagtatag
    22021 gaaactaact gcttcttccg acgattgaat ggagaaatga ttgattctta ataattccag
    22081 ccatttttcg ttcattggag aatcagccga tagttctcta cgtttggttg tctgctgatc
    22141 atttcgctgg gttaacaagt ataacctttg ccaatagata ctttcgtgat ctaagtcgca
    22201 gcaccactct aaatattttt cgatccccaa aaagaaatgt tgtttgtttt cgctaatgaa
    22261 ttttaagata tcttgatgga ctatgtgaga actgcttttg atcgtataca aataagcatc
    22321 ttccaaatct tgaaaatatt tataaaaagc accgcgcgac atccccatct tgtcaacgat
    22381 ttctgagact ttgacttggc tgatgtgctg tgagcaaaat atctccagta ataggtcatc
    22441 gattctctgt ttctttgcgt tcgataaatt gaaaaaagtt tcttttggca tccacatctc
    22501 tcctttatct ctgattatac gtggatagcc cttcattgtc atgaaggatt cattccttct
    22561 ttttctcttc ttctgtcaag tacccatctt ccattcgata aacgcgatca ctccattgaa
    22621 tcatacggac atcatgagta accataatag tcgctttttg tttctcatga gcttctttaa
    22681 ctagtaattt gacgacttca tatgcatgat ctgtatccaa actagctgtt ggttcgtctg
    22741 ctaagatcaa gcttggctca ttatataaag cgcgagcaat tgccactctc tgtctttctc
    22801 caccagaaag gtctttagga taactatttt taagtgactg gatatctaaa gattgcagca
    22861 aggaatcgat ttttgttgaa tcttcttttt ttgaagtaac ttggtcaact agttcaaatt
    22921 gttcctttac cgttaaaaaa ggaatcaaat tagagctttg gagaataaat cctatttctt
    22981 taaagcgtaa atctgctcgt tttttttctg gaagctcagt tagtgagtga ccgttgatca
    23041 ctatttctcc ggaagtcggt gtttgcaatc ctcctgaaat ggtaaggaaa gtacttttac
    23101 ctgaaccaga aggaccaatg atgctgacga attctccttc ctttacataa aaatcaattg
    23161 ctttcaaagc tgagaccttt gtatgaccag aaccaaatgt tttggtaact tttttcatcg
    23221 ttaatatttt tttcattttt attaacctcc tattgctgta attgggtcta ctttggttat
    23281 cgtacgtatc gaaaacaatc cgcctagcat tgcgacaatg atcaaaatcc cactatatag
    23341 caaccattgt gaccaaaaaa cagcaaaagg catcgcgctt ggtaaaatca gactagtcaa
    23401 ataagcaaac aaaagagcaa gcagaacgcc taccacccca acaataaagg actgtgctac
    23461 taaagattta gcgatgaaga aatttttgat cccttgtgct ttcattactc caaaaatagc
    23521 agtcttctga agtgtcatca cgtacatgaa aataccgacc acggcagcaa ccactaagaa
    23581 caaaaagtat atcatcgcat ttaaggtcat attttgggca gaatagccag gaatactttc
    23641 aatgaatgtc ccaatagtta ataactgtag acccttcgat gctttttctt tcgaaatttt
    23701 agctgaatcc tttattacga tcccattgat cggctgttct tcttcagaag caaacggctg
    23761 ttgtccatac ttcaaagcag tccacgtatc tagggacgca tagatgacgg gagaaactgt
    23821 gtaataagtt tcaggaaaga taccgacaat cgtcaaagga tcgtcgtaac tgccaatttt
    23881 gatcgtatct ccaattttat agcctgaatc agccagattt tgagagatga tgatttcatt
    23941 ctttgtttta aattcatgcc ctttcgtgag ttttggtaat aaaaatgctt ctttcgttgt
    24001 gccgaaaact gtaacatttt ctttgttttt tcctttgatt gctccgctgt acaatccgat
    24061 tggtgctttc tctcctcctt caatgtattt cagatctcct cttgttaatt gtgaagctgc
    24121 aaatacttga tttgcatcct ccgacaaaac aatctcttgt gcgtcccaat catcgattgc
    24181 ttttttaaac tcttctgaaa gtccattcgc tagtcctgac aacatgaata cgacatacgc
    24241 aatcaagaac ataataccga cgatcaagcc atatcgtaat ttagaatagc gaatttcttt
    24301 gatagctaga aacatttgtt tttcctccct atgatagatt gatagtgaca aaatgtcact
    24361 tgttgaatag tgtaactcta aagtgacaat ttgtcacttg tgttgttttt ttcttatcaa
    24421 taaattgtct aagacatctt tcgataaaac cttaacatga gtcataaaaa atttatttaa
    24481 gccttattta tgctttccat gataaactaa agtgaccaaa tcaatgaggt gggaaaatga
    24541 ttaaactatt agtagtagaa gacgataaag tattatccaa taatataaaa gaaatactcg
    24601 ctgcaatcgg cgagataaca caagtttatg atggtagtga aggactgttc gagttggaaa
    24661 gtggagttta tgatcttgca atcttggatt tgatgatgcc ggaaatgaat ggatatgaag
    24721 tgttagcaaa aatacggaaa gaaaaaatac agactccagt attgattttg actgcaaaag
    24781 atagtttgga agataagatt gaaggatttg aacgaggtgc agatgattat ctaacaaaac
    24841 ctttctatcg agaagaactg atcatgcgcg tgaaagcatt attgaaacgc tcgctaggtc
    24901 tctttgatga aaatgttctg aagtataagg atatcagttg tgatttaaaa agcaatgaag
    24961 tcttgtataa agaacaagtt ttgcccatac aaggaaaaga gtttgaattg ctcgtttatt
    25021 ttttacaaaa taagggaatc attttgacaa aagagcagat atttgaccgg atctggggat
    25081 ttgattctga tacgacgatt acagttattg aagtttatat gagcaactta cgaaaacatc
    25141 tgcgaagtac tggattggat aaagaaatca aaaccttacg taatgtcggt tatatactgc
    25201 aaagggtgtg atgcaatgaa tggagatatt acacgaaagc aacgtagtcg cttttttgcg
    25261 acaaatgtag cagcatttgc ttttatcttt tttcttttgg gattcattac tttacagata
    25321 ttaaaccaat ctgcatacag agaaacagat ctgtcattag agaaaataaa ttttgattct
    25381 cgaacagtac aattagagat acaaagatat cagcaaggcg atcccttttt aaacccgact
    25441 caaacggaac aaaacagaac aaacatggaa cagccattaa tggaaccatc aaatgaccgt
    25501 tttaacactc aagtgatctt gtggtctaaa aatggtgaga tattgaataa agcagctatt
    25561 ggtgggcgtt tcaaccaaat caaagaatta aaaatggata cgaaaaatct gaataccatc
    25621 caaaatattg aattaaatga agacagtggc tcatctgccc tctctttccg ttcgattacg
    25681 aaaaaagcgg agacgaatca agatggcgtt gcctacatcc aaattttaga aaatacaaat
    25741 caaatcaaga attcattagc gacttttcgc acgattatga ttttgtgtat gattgttttt
    25801 tggattctct ctattggtat cagttattac ttgtctagtc taagcatgcg ccctattatt
    25861 ctttcttgga gaagacaaaa agaatttgtt gagaatgctt ctcatgaatt gcgcacaccg
    25921 ttaacgatta ttcaaaatag tttggaacat ctttttacca agcctaatca tactattatt
    25981 gaagaatccg aaagcatcgc tcaagcattg tcagagacga ggcgcctcac tggattgact
    26041 tcggatttgc tgacaatcgc tcggaatgat tctgatcagc agctgctttc aaagcaaatg
    26101 atcaatacac aagaatatat cgaacaactt gttaaaccat ttcaagagat ggccatcata
    26161 gatggaaaag agtttattct ccataacgat gcaacattag aagtaccaat tgatgaaaaa
    26221 aaaatccatc aagttttggt tattttgctg gataatgcat taaaatatac gaatccagaa
    26281 gataagatca ttttggattc atctgttaac cataaagaat ggctgattca cgtaaagaat
    26341 actggccctt ctatcagtga agaagatcaa gcaaggattt ttgatcgatt ttatcgggaa
    26401 gatcaatctc gggcgaaaga gactggcgga tacgggcttg gcttggcaat tgcaaaacag
    26461 gtaatcgaac agcatcatgg acagatttct gtatccaatt atcttccaca aggagtcgat
    26521 tttaaagtcc aattgccgtt gaagcctaaa aaataatgct tatccctaaa aaagggctgt
    26581 gacaaaaatc ttgtcacagc ccttttttgt tgcgaataaa cggtgttcca gaagtagctt
    26641 cttcggaaat aagccgaaat ttctttaagc tgaccacttc tgtcacaacc tctttagctt
    26701 acgcttacga ttttttattg cggtcttcaa tgtgtacatc accgcttgtg tcaatatcca
    26761 attcttctcg gctaacatct tctgtcactt tttcaacatc ttcatgttct tctttatgaa
    26821 tcccaacttc ttcacgaata actgtatgtt tgcttacatc tacttgctct tctttgattg
    26881 ggatagtaat cgtgtcatct tccaattttt cgtctgttcc ctgtgaagat tgatctgtta
    26941 ctggtttgcg ttcgatgacg atttcttcac gtttgaccgg tacttctacc gtttcagtat
    27001 cgttgaccac atgtttgtgg atgtcgactt ctccagttgt cacatcatgt gtatttacat
    27061 ctaatttttc ttcttttagt tgaattgtat catcatctag atttggtttg cgatcgatgt
    27121 cttcagtctt gcttgtaccc attgtatcag tctcgccagg tacgtccatc ggatcagttc
    27181 ctggtgtcat attcaatgga tccgttgtat tttgaaagcc tgtcgtgcca cctacgtcca
    27241 ttggatctgt tccagtgcca gtttctaatc cagtccccat tgtgcttgct gggctaacag
    27301 tatcttgtgt atccattgta tcttctgttg tttctggctg acgatagcct tttactgtga
    27361 tgacaaattt tccatcagaa atatctcctc tatattgata taaaggatca ttttctggtg
    27421 tagccgtctc agaatcatag gtatcaaaag aaaaagtatc ttttattttt tcccataaag
    27481 aacggtcttc ttcaccatcc atccgatttt catctgtttc aacatctata ccagacaatc
    27541 cgtcaaatcc tagtctagat gctgcttcat cagtagtata aataacgata tcatctcgtt
    27601 catacccttc gttacgcaac cgttcaatta ctgataatgc ttcttccctc gtactatagc
    27661 ttccgatgac cgttaaattt ttctcttcca tgtaaattcc tcctagcaaa tagatttatg
    27721 attggtatat tgttacttat aaatttattc ta
//
LOCUS       DAJSMK010000028        26960 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.028, whole genome shotgun sequence.
ACCESSION   DAJSMK010000028 DAJSMK010000000
VERSION     DAJSMK010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26960
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.028"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..1196
                     /locus_tag="ON488_001237"
     CDS             <1..1196
                     /locus_tag="ON488_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HCR3231441.1"
                     /translation="EELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQPLNDELRE
                     IIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDYGKYGYES
                     KYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMTAGGVMKR
                     LDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTGETLYLGS
                     TSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLTYRDAERT
                     AFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTLQKALHWL
                     QRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERIDTAVPQE
                     NDGIF"
     gene            2185..2394
                     /locus_tag="ON488_001238"
     CDS             2185..2394
                     /locus_tag="ON488_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HCR3231442.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            2506..4119
                     /locus_tag="ON488_001239"
     CDS             2506..4119
                     /locus_tag="ON488_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3231443.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            4154..5365
                     /locus_tag="ON488_001240"
                     /pseudo
     CDS             4154..5365
                     /locus_tag="ON488_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            5388..6314
                     /gene="glsA"
                     /locus_tag="ON488_001241"
     CDS             5388..6314
                     /gene="glsA"
                     /locus_tag="ON488_001241"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HCR3231444.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6522..7982
                     /locus_tag="ON488_001242"
     CDS             6522..7982
                     /locus_tag="ON488_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231445.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            8203..9966
                     /locus_tag="ON488_001243"
     CDS             8203..9966
                     /locus_tag="ON488_001243"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HCR3231446.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            10050..10508
                     /locus_tag="ON488_001244"
     CDS             10050..10508
                     /locus_tag="ON488_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HCR3231447.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10617..11300
                     /locus_tag="ON488_001245"
     CDS             10617..11300
                     /locus_tag="ON488_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCR3231448.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            11447..12061
                     /locus_tag="ON488_001246"
     CDS             11447..12061
                     /locus_tag="ON488_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HCR3231449.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            12077..12283
                     /locus_tag="ON488_001247"
     CDS             12077..12283
                     /locus_tag="ON488_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231450.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            12824..13954
                     /locus_tag="ON488_001248"
     CDS             12824..13954
                     /locus_tag="ON488_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HCR3231451.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            14046..14801
                     /locus_tag="ON488_001249"
     CDS             14046..14801
                     /locus_tag="ON488_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCR3231452.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            14859..16898
                     /locus_tag="ON488_001250"
     CDS             14859..16898
                     /locus_tag="ON488_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HCR3231453.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(17007..18158)
                     /locus_tag="ON488_001251"
     CDS             complement(17007..18158)
                     /locus_tag="ON488_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HCR3231454.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(18312..18842)
                     /locus_tag="ON488_001252"
     CDS             complement(18312..18842)
                     /locus_tag="ON488_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HCR3231455.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(18941..19291)
                     /locus_tag="ON488_001253"
     CDS             complement(18941..19291)
                     /locus_tag="ON488_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HCR3231456.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(19448..20977)
                     /gene="ahpF"
                     /locus_tag="ON488_001254"
     CDS             complement(19448..20977)
                     /gene="ahpF"
                     /locus_tag="ON488_001254"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HCR3231457.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(20987..21550)
                     /gene="ahpC"
                     /locus_tag="ON488_001255"
     CDS             complement(20987..21550)
                     /gene="ahpC"
                     /locus_tag="ON488_001255"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HCR3231458.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(21694..22356)
                     /locus_tag="ON488_001256"
     CDS             complement(21694..22356)
                     /locus_tag="ON488_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3231459.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            22540..24186
                     /locus_tag="ON488_001257"
     CDS             22540..24186
                     /locus_tag="ON488_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HCR3231460.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            24177..25259
                     /gene="uxuA"
                     /locus_tag="ON488_001258"
     CDS             24177..25259
                     /gene="uxuA"
                     /locus_tag="ON488_001258"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCR3231461.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(25367..26920)
                     /locus_tag="ON488_001259"
                     /pseudo
     CDS             complement(25367..26920)
                     /locus_tag="ON488_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         9094 a         4640 c         5349 g         7877 t
ORIGIN      
        1 ttgaagaact aagacaaaag cgtgaggaat acggagtaac acaaacaagg cttgctgttg
       61 cctgtggtat cagccgtgaa tattacaacc gcattgaaaa aggaaaacag ccattgaatg
      121 acgaattaag agaaatcata gaaaaacaga ttgagcgttt caatccgcaa gaaccactat
      181 tcttattgat tgattacttt cgtgtccgct ttcctactac ggacgcattg gcgattatcc
      241 gtgatgtatt acaactgaaa tctaattaca tgctttatga agattatgga aaatacggat
      301 atgaaagcaa atatgtactt ggcgacatca atatcatgtg ttccatgcag gagcatttag
      361 gtgttttatt ggaactgaaa ggcaaaggct gtcggcaaat ggaatgttat ctgctggcac
      421 aggaacgctc atggtatgac ttcatgctgg attgtatgac ggctggtggt gtgatgaaac
      481 ggcttgattt ggctatcaat gataaagcag gaatattgga tattccaaag ttaaaggaaa
      541 aatacaaggc tggcgaatgt atgtcctact tccgtatgca gaaagattac agcggtacag
      601 aaaaatgcgg tagcgattta ccaaagaata caggagaaac cttatatctc ggttcaacaa
      661 gtagcgaatt atatatgtgt gcttatcaga aaaattatga gcagtatgtc aagaatggca
      721 cagaaattga agatacggag attaagaacc gttttgaaat acgcatgaag aacgaacgag
      781 cctattatgc ggttgtagat ttactgacct atcgggacgc tgaacgcacc gctttttcta
      841 tcatcaatca ttatgtccgc tttgttgaca gagaggacga caagccaaaa agtcaatgga
      901 taacaaatga tgattgggca tggtttgtag gggaaaacag agagccgata cgcttaacca
      961 caaagccaga gccttacact ttacaaaaag cgttgcattg gctacaaaga caagtcgcac
     1021 caaccataaa aatggtacag gcattagaca gagaaaatcg tacaacgata ctgaaagata
     1081 tgattgagca ggcagaacta aaagacaagc ataaacattt attacaatta gagaaatcaa
     1141 ccatagaaga acgtatagat accgctgttc cacaagagaa tgacggtatt ttttaatgta
     1201 attgaaaaat ttcagattta gtcagcaaag agctgttttc attccctatg tgaagtgaaa
     1261 gaagaaaaat aaatttttta ttaaatctgc aacaaaatgg ctacttgcgt acagatatgg
     1321 tgcgagaaaa ggaaatctaa actttttttg aaaataggtc attaaatcgg ggcttgctgt
     1381 ccctatatga agtgaaagaa gaaaaaagtt ttgaaaaaat gacggaaatt cgtgattagt
     1441 ggacagtctt ctgtgaaaag aggaaaaaca tcatcatttt gtattcaaac aggcattagc
     1501 agttgagtgt tgatgtgaaa agatgaaaat actttgttct caacttaaca atttaaggtt
     1561 tccgttccct atatggtgca aagaaaatat ttcattctat tgttggcagt aacggtatgg
     1621 tttgggtagt tagggtgtga aaaggaaaat attctttttt catcatcaac ttagcaaaat
     1681 gacattttct atccctatat ggtgcatgaa aagaagttaa aatttttcca tttaaactta
     1741 gcaaatggac gtttgctgta cagatagtag tgaaaaagga gaaaatcaac cgttgattgc
     1801 caaaatgaac cgttccattt gtactaataa tggaaaaagt tttggatttt ggttacgttt
     1861 ctcctctttt ccaacgcgat atataggaaa gacgattttt ttctttcaat cgttctttga
     1921 caactgaata aagctattca atacgtttga cagacagcta gccgttgaaa caaatacgcc
     1981 acgacctttc ccctgcaaga gcgagcgaaa acctatttgt gttcttgtaa aagatttgtc
     2041 ctcttttatc gccatgacct gtactgtcag ataatgatac tcccgtacag ccacagcttg
     2101 agcattaaga gcgtcgcacg caatgggtac ggctacataa gaactatgca gaggtggaac
     2161 tcctgtgggc tatgacaaaa gccgttgaat tgcttagaaa gattttacag aaagggggta
     2221 tgtgttattg ataatgctgt aaaaacaatt caaaagaaaa atggcaagtg tggcattggc
     2281 aacagaggaa agacaaagat tgtagtaaaa gagcattttt ccgaaaaggg caaaacaatg
     2341 gaagaacttc taactgatgt catgctggaa aaagcaaagc agacaatcgc ataaaatcgg
     2401 tgcagttgta agaaatagat tgaatgacaa aaagtacccg tgttatactt tacttgcaag
     2461 caggtattgt aaacacgggt tagttataaa ggaggataac tgacaatgaa acaacagatt
     2521 tacaatactg cactttatct taggttaagc cgagatgatg aattacaggg cgaaagttcc
     2581 agcattacca cacagagaag tatgttgcgt ttatatgcaa aagaacatca tttgaatgtc
     2641 attgatgaat atattgatga cggctggtcg ggaacaaatt ttgacagacc gagttttcaa
     2701 agaatgattg aggatataga ggcaggaaaa atcaactgtg ttgtaacgaa agacctttcc
     2761 cgtcttggca gaaattatat tatgacagga caatatacag aattgtattt ccctagtcat
     2821 aatgtccgct acatagcgat tgatgacggt gtagacagcg aaaaaggcga aagtgagatt
     2881 gcaccattta agaacatcat caatgaatgg gtggcaagag atacaagccg taaagtcaaa
     2941 tcagcattta agacaaagtt tgcggagggg gctcattacg gtgcttatgc tccgttagga
     3001 tataagaaac accctgacat caaaggaaaa ctgttggttg atgatgaaac aaaatggatt
     3061 attgaaaaaa tcttttccct agcctatcaa ggttacggaa gtgcaaaaat cacaaagcag
     3121 ttaagagcag aaaaagttcc gacagcgtca tggctaaatt ttacaagata cggtactttt
     3181 gcacatatct ttgagggaaa acccgaaagt aagcgttatg agtggacgat tgctcatgtc
     3241 aaggcgatat tgaaaagtga ggtttatatc ggaaacagtg ttcacaatat gcagtctacg
     3301 gtatcgttca agagcaaaaa gaaagtgcgt aagcccgaaa gtgaatggtt tcgagtagaa
     3361 aacactcacg agccgattat tgacaaggaa gtgttctatc gtgtgcagga gcagataaaa
     3421 tcaagacgca gacagacaaa ggaaaaggca acgccgattt ttgcagggct tgtcaagtgt
     3481 gcggattgtg gttggtctat gagatttgga acgaataaga caaataaaac gccttacagt
     3541 tattatgctt gcagttacta cgggcagttt ggcaaaggta attgttctat gcactacatt
     3601 cgttatgatg tgctgtatca agccgtattg gaacgcttgc agtattgggc taaggcagta
     3661 cagcaggacg aagaaaaggt attgaacaag atacagaaag ctggcaatgc agagagaata
     3721 cgggaaaaga agaaaaaggc aagtacattg aagaaagccg agaacagaca aaatgagatt
     3781 gaccgtttat ttgcgaaaat gtatgaagat agagcctgtg agaagataac agagcgaaat
     3841 tttgtgatgt tgtccagcaa gtaccaaaaa gaacagatag aactggaaca gcagataaca
     3901 agcctaagag aagaactaag taaaatggaa caggatatga taggtgctga aaagtggatt
     3961 gagttaatca aggaatattc cgtaccaaag gaactgacag caccattatt aaatgccatg
     4021 atagaaaaaa tcctcataca tgaagcaaca acgaatgagg ataacgaaag aatacaggaa
     4081 attgagatat attaccgatt tattggaaga gttgagtaat caacaagagt aatattttta
     4141 actaagggaa accggcggtg tctatacttg ggtcagtcgc acattgggaa aacgattcgg
     4201 ttttgccgca atctttttcc aatggtttga gataacagtt ggctacttga ccatgctgta
     4261 tttcttaact ggtgcattat cctatgcaac gggtattggt gctatacaaa acaataaata
     4321 tctgaaattg gcaatcctat tgattatttt ctgggctatt ttactctcac agttaaaagg
     4381 aaccaaatac acttcattga ttgctcggat cggttttgta gctggtatct tgttgccagc
     4441 attagtcttg tttggcttag ggatccatta tgtcgcttca ggcgctccac tacaaacgat
     4501 actgtctatg aaaacattga ttcctgattt ttcgaaattg cctacgctgg ttgtttttgt
     4561 ttcctttatt ttagcatata tgggcgtaga aacatctgcc agtcatgcaa atgaaatgga
     4621 aaaccctaaa aaggattatc cattagcaat gtttgtattg gttattctgg caatcatttt
     4681 agatactttt ggcggattga ccgtcgctac tacagtacct caacatggtt tgtctcttaa
     4741 tacaggggtg attcaatcgt tagaattcct attaagacac attgatccaa atcttgcatg
     4801 gattgcgaaa attcttgcga ttcttgtttg tttaggtgtc atcggagaaa ttgcttcttg
     4861 ggtaacctct ccttcaaaag cacttcacgt agcagcagaa gaaggattac ttcctgaata
     4921 ttttgcaaaa gaaaacacac acggtgttcc tgctcatttg atgatcgcaa atgggatcgt
     4981 tgcaacaatc tgggcagccg tctttacatt aagcggcggg gggaataatc tttcatttct
     5041 tgcagcgatg tcattgactg ttgtaatcta cctgatgttg tactttatgt ttttcgcggg
     5101 ctatttgaag ctggttttta aagatgacag tcttgaaaga gcctatcagg ttccaggcgg
     5161 aaaagttgta aaagtaatcg ttgcttgttt aggtcttttg acttcacttt ttgctttttg
     5221 tatctcattt gttccacctg ctagtatcgc agctggacag catgggattt atgaaacgat
     5281 tctgattgtt tcttatctta tcgtcttagt tattccattt acgatctacg catgccgtca
     5341 taaattccag catgcagaaa aataaaaaat gaaagctggt tattcaaatg gaagtaaaag
     5401 aattagaaca attgattgga aaaaatttcc actattatca aacaggacaa gtggcggatt
     5461 acattccagc attagctgaa gtggatccca aacaattagg tatggcgatt tatgatttgg
     5521 atacaaaaca actgattgag ggaggagacg ccgatgtgcg ctttgccatc gaaagcatgt
     5581 caaaagttcc cgtattgtta ttagcaatca aagacaacgg aatagaaaaa gtctttcaaa
     5641 caatcaacac ggaaccaacc ggttttgcct tcaattctat catgaatatg gaaatcaatc
     5701 atcgcaaaca tccaatgaat ccttttgtta atgcaggagc gattgcaaca acctcgttga
     5761 ttgccggtaa agatgcagat gaaaaatttg agcgaatctt gtcatttatg aaagagatct
     5821 gtgatgatcc taatatcaca ttgaatgaag aaatctatca ttctgaatca agaacaggtg
     5881 atatcaatcg ctctcttgct tactatatga aaggtaatca aatgatcgaa ggagacgtac
     5941 cggagatact cgatgcttat ttcagacaat gctccctcaa tgtcaccgct acaggcatag
     6001 caaaattagc tgctgtgctg gcaaataaag gaattgctcc ttggaatggc aaacaaatca
     6061 ttactgaaga aagtgctaca atcgtcaaat caattatgac aactgctggt ttgtatgatg
     6121 aatcaggaga gttttccgtc catgttggtg tacctgcaaa aagcggtgta ggcggcgggt
     6181 tgatggcagc tgtgccaaat cgttacggca taggtgtctt cagcccggca ctagatccat
     6241 ttggtaacag cgcagctggt atccaattgt tgaaagatgt agtcaaagaa ctagacgctg
     6301 acatctttga ataaccattc ttgaaagagg ctggggtaaa agtccaaacg gctcaaagct
     6361 acctacaatg aggctgaaat tgtgagcttg tttgactttt gtcccagttt ctttttttat
     6421 tggtttttga aagggctttt ctaaataaaa aggaaacaaa aatacgattt acagatatga
     6481 ttaaataaaa tcataagaaa aactggaggc gtgtatcagg aatgctggaa aattacatcg
     6541 agcgaaatat atttagaaaa gtgtatctgt gtgaacaatt atttgaattc caagaaatag
     6601 acatcgaaca aacagctatt tctctaaggg tgactacacc aacgatcctt cacgatctag
     6661 aaagtctagc cgagtgtcta gaatattgta taaaagaaca agtaagagag aagcataagt
     6721 ataaactcgt attcaaacat ggtattgctc tttctgagct cacacagttt ctgtacggtc
     6781 aatcttattt tttaaagttt ttaagttatt attttaatgg tatattcacg agtacagaac
     6841 tggctgatct tgaatttatt tctttgagta aagtatatac aatcaaaaaa atcgtattgg
     6901 atttttttaa agaaaatgat tatttgaaaa ataaagaaat cattatccca gaatttgact
     6961 cgcggaacat cttgctagct ttagtacgtt atgtcaattg ggaaggctat gaaaataaaa
     7021 atccgtatgt agaagaagct tgtaacgagt tgattgatta tgtagagact cattttttta
     7081 aaagaagata ttcggaagat gaaaagtcct ttatcatacg agaaatagag atcgcaatcg
     7141 gaagaaaggc atttcccctt ggactgaaag aagaagataa gaaaagcgca gaaacgaagc
     7201 cgttatttca attagtctgt caaggattgg aagagcaaaa aggaattcta gacttacaag
     7261 aagaagatgt ctattatatt ttttctttgt tcaacagtag aaattatacc aatgagaaca
     7321 tggagctgtt aagaaaagat ttcgaagttg tttataaaaa ttttgttctc aatgacctat
     7381 cactgaatga attgatttta cagattatta gtatcgctga aatcgacgat gcagaaaatt
     7441 ttattttcaa gcaatccttt ttacaatttg tccgtacgtt gtgggcagat ggacaagtat
     7501 ttttaccgga aaggatctat cttctatcag aaaaagaaca acttctgtac ggaaaaattg
     7561 tagaaatatt ggaagagtgg aaaaagaaaa atcaaatcca actaagatgg aatgaaaatt
     7621 tcattcgaaa attcgtcaaa agtctttctt tgatcaacag tgaacaagcg gggagacagg
     7681 aaatagaaat ttttgttgtt tcagaaagtt cagtcaaaca atttttttat cgaacccaat
     7741 ttcatttgta tgcggaagaa ggcatcgctg aaataaatcc tattttattt cgttcattag
     7801 aagaattgcc tgatgaatgt ctatgtgcga aaaaaagagt ggttttgtgc gatgctgcta
     7861 gctatcaaaa tggattagaa actgaaaaga caaagatcta tccaatctca ttaaaaggtg
     7921 caaacatcca tttgtatcat attgctcagg aacttcacct attaaaaaaa catatttctt
     7981 gatgagacct taattaggag accttctaca aagcttttta attgtctgta gaaggttttt
     8041 atttgagtcc tgattcgtgc gaagatctac ttatataaca agctttctct gaaatttttt
     8101 taaaatgcta ttgacttaga gtcaactcta agtagtagaa tagataaagt gtaacaaatc
     8161 tattttcatt aaaagaagat agtacggagg agagaatgta ttatgagtac agtattacat
     8221 gtattggatg caatcaatag ccccgcagat gtcaaaaaat tatctgttga ggaaatgaaa
     8281 cagttggcag aagagatgcg ccaaaaaatc ttgcaaaagg acagcgatgt aggtgggcac
     8341 gttggtccga atctaggtgt agtagaatta acgattgcgt ttcattatgt atttgattca
     8401 ccaaaggata aaatcgtttg ggatgtttcc catcagtctt atggtcataa gcttttaact
     8461 ggtcgaaaaa atggttttga aaaaggacat taccgtgaag tgagcggata ttccaaccaa
     8521 catgaaagta aacatgacta ttttacagtg gggcacacat ctacatctat cagcttagca
     8581 acaggtttag ctaaagcgag agatctgaag aaagaatcag gaaatgtggt agcatttatc
     8641 ggtgacggct ccctaagtgg tggcttagct tttgaaggat tgaacaatgg tggtgtttta
     8701 caatccaatc taatcgtatt agtaaacgat aatgagatgt ctattgatga gaatcatggc
     8761 agtttatata aaaacttagc tgagcttcgt caaaccaacg gtaaaagcag caataaccta
     8821 tttaaagcaa tgggatttga ttatcgttac gtggataatg gaaacgatct ggaaacggtg
     8881 atccgtttat ttgaagaagt aaaagatatt gatcatccga ttgtacttca cgtccatacg
     8941 gaaaaaggtc gcggttatca gccggcaatc gataataaaa tgaaatatca ttggcatgta
     9001 ccatttgatc tgtccaccgg ggaggcaaag caagtaactt ctggagaaac atttaatatg
     9061 atcatcatgg attatttgga taagaaaatg caaacaagta cagctcctat tgccgcagtc
     9121 aatgcagcga taccaggcgc ctttggactg aaaacattcc aagaaaaaca tccagatcat
     9181 tattttgacg tggggatcgc tgaacagcac tctatcactt tcgcttctgc tttggcttct
     9241 cagggagtac gtccagtcgt cttccaatca agtactttct tgcaacgggc atatgatcaa
     9301 ttatcacatg atttagcgat caacgagaat ccagtgatta ttttagtcgg tggcggaacg
     9361 atctcagcta gtgaccgaac acaccaagga acatttgaca ttccttactt atcaagtatc
     9421 ccgaacatca aatatcttgc tccagcaaca aaagaggata tgatctctat gctagattgg
     9481 gcgttcgaac aaacagcgca gcctgtagca atccgaattc ctacacatgg tgtagaacat
     9541 ggtacagcta tcgcaaatga ttatagtatt ccagcctatc aaacagtaaa taatggagga
     9601 aaagtagcaa ttttagcttt aggcggtttt cttgaattag gaaaagaaac agtaaaagct
     9661 tttagaaaaa aaggaatcga agcaacgttg atcaatccag gaacgatcac agaaaatgac
     9721 gtagaaacat tagataaatt aaaagaaaca cacgaattag tcatcacatt agaagatggt
     9781 agtttgtcag gaggatttgg cgaaaatatc agtcgttatt atggtgattc ttcaatgaac
     9841 gtattaaatt ttggtgcaga gaaagaattc acggatagcg ttcctgtagg gcagctttat
     9901 gaacgttatc atttaacacc aaaacaaatc gttgaagata gtctgcgtgt cttgaatatt
     9961 caataattca ttatgctcac catccagata attgtttata ctagtatctg gatggttttt
    10021 tcattataaa aagcaaaggg gtggatgtta tgtatcagca agtagaagaa tatgtcaaaa
    10081 agttccaaga aaaatatcct agttatcaat cagaaaaatt aggtttcttt tcatttgggg
    10141 atacagaaaa aatggcagac gagttgagcg aactagttgt aaaaaagata aagactggta
    10201 catcaagtgg ttacgatctg tataaacaag agaatgagcc tttaccaaaa gttggtcaat
    10261 tagacgtggt cctgaatgga aaaaatgaac cagtttgtat catcaaaaat ataaatgtga
    10321 ccatcttgcc ttttagtgaa gtcacgaaag agcatgcttg gaaagaagga gaaggggatc
    10381 ggacattagc ttattggcgg aaagtccatg ctgagttttt taaacatgct tataaagaag
    10441 cgttgaacat agaatttaca gaagagaagc tggtcgtata cgaagaattt gaagtaattt
    10501 tcttttagta agaaaggtct gctgaaagaa atagctcatt attgtctcct gaatagaaaa
    10561 gggttacatt tttatatgaa gctgtatttt tatataacat tactggagga gatattgtgg
    10621 atacactgga acaaatcaaa ggcggagtcg tcgtttcttg tcaagctttg gaaaacgagc
    10681 cgctacacag ttcttttatt atggggagaa tggctttggc tgcaaaagaa ggcggagcag
    10741 ttggtattcg agcaaatacg acagaagata tcaatgaaat caagcgaatc gttgatttac
    10801 cggtaatagg gattatcaaa agagattacg atgggtcaga agtgtttatt actgcgacag
    10861 aaaaagaagt ggaagaactt ttggagacgc aagcagaaat cattgcactg gatgcaactt
    10921 ctcgtaaacg tccgacagaa aaaacaactg ctgaacttgt ccaaatgatt cacgaacacg
    10981 gtcggttagc tatggcagat atttcgactt ttgaggaagc gcttcaagcg caagaagatg
    11041 gttttgatct tttgtctacg actttagcag gctatacaga atattcacga aagacgcaga
    11101 cacctgattt tgatttattg aatcaaatca tagaacaagt cgatatccca gtaattatgg
    11161 aaggacatac tgactctcct gaacaagtag agaaagcata tgaattaggt gctttttcag
    11221 tcgtagttgg atctattatc acccgtccgc aattgatcac taaaagatat gtcgaagccg
    11281 caagtaaagc aaataactaa aaaacacgca cggcacagat tcttgacaaa aaagaaaaat
    11341 tgatagatag tttaaagcag attctaagaa gatgaaaaaa gcattacttt tcattttgtc
    11401 ttcaagatct gctttttaac gaattttata gaaagaaggc gaaaccatgt ttgaacggag
    11461 tccttcagaa ttgacagaac gtgaaaatta caagttgctg attggttcag tcatccctag
    11521 accagtagca gtagtaacga ctaaatcagc aaaagatata gtgaatatcg cacccttcag
    11581 ttacttcaat atcgtcagtt cgaatcgacc catcttatcc ttggcgatcc agagaaaaca
    11641 agatgcagta aaagacacag caaagaatat tcttgagaca agagaagctg ttatccatat
    11701 ccttgatgag gacaacgtag aagaagtaaa taaaacagca gccaatctgc ctaatgagga
    11761 aagcgaactg tacctgactg acttgacttt aactgattca gtaatcattt cagtaccagc
    11821 attgacagaa gcaaaagttc gttttgaaac atccttatat gaacatgtcg agatacggaa
    11881 taaaaataaa gtaacagctg atttattttt gctagaagta cagaaatatc atttaaatga
    11941 aacagtctat gatgataaga caggaaggat cgatccaaga aaattgaatg ctgtaagccg
    12001 tttggcagga aatgattatg cagcaatagg agaaattttc acgattgcac gtcccgaata
    12061 aaaaggagca ctagttatgt taaaaataag ctataaacca tcgacagatt caaaagaaat
    12121 gaaaaaagaa tatgaaacag tgaatgattt tctgcaaggg cagtacttag aagttccgcc
    12181 attgcaagac cattttgtcg ttactactgt tactttagat ggtaaggaaa tagaaatgcc
    12241 agatcaaacg attagcggat tgtttaatta ctttaacaaa taaatattta ttccgaaaag
    12301 tgaaaaaaca tataaaaaaa cacataaaac taaaaaatta tcaaagaatc ctggtgcaac
    12361 tgaaagaatt tgcaacggga ttctttcaac ttatttgtta tttttttcta aaaaatatta
    12421 aagattgtta aatttcacta tttcatttca aattccattg cctaatcatt aggaaaagtc
    12481 tatcatgaac tcgtaaatag aatatagtaa taaccttgtt aggtgaggct cctatacaaa
    12541 cataggctgt tgcccagaaa cgtcgaaagt cgccaatggg taaaacagaa actgttggat
    12601 taaggctttt tccaatagct aagaatgttt tctttacgtt gtatagtgct aaaactcgga
    12661 cgatgagatg atgctaggtc agaattcttg ttcgaaaagg tttctgacct tttctttata
    12721 tttttgtgac tgacttattt gatgagacaa actcgctcct cacctgacaa gtggattgct
    12781 gtgtgaggag gagatgcggt gaaaaaagat cgattggtgg attttgggtc cttatttgac
    12841 tttgtccatg atcggtcttt tagaagtata cagtgccagt tcttatcgtt tattgcaagc
    12901 cgatgaaaat acaaaaagtc tattattgcg tcaactaatt ttcatatttt tgagttggag
    12961 cgtgatcttc ttagctcgtt cagtcaaact acactattta cttcacccta aaatagcagg
    13021 atacggttta gccttatcga ttttcttttt agtattagta agaataggga tattcggtgt
    13081 cactgtcaac ggcgcacaac gttggatctc tctgtttggc attcaattcc agccttctga
    13141 actggcaaat ctttttttga ttttttattt aagctggttt tttcgtgacg gaaatagtag
    13201 cccaaaagat ctaaaaaaac cattcctgat tacagtaggt ataacttttc tgattttatt
    13261 tcagccaaag attgctggag cattgatgat cctttcgatt gcgtgggtca tattttgggc
    13321 agcggcggtt ccatttaaaa aagggatcta tctaatcgtt actttttctg cattgctgat
    13381 tggagcagca ggcggggtat tatatttagg aaataaaggt tggcttccac agatgtttaa
    13441 tcatgcttat gaaaggatcg cgactttaag agattctttt atcgatagtc atggtgcggg
    13501 ctatcaaatg acccattcgt tttatgcact atataatggt ggcatatttg ggcggggatt
    13561 aggaaatagt atcacaaaaa aagggtatct tccagagaca gaaacagatt ttattttttc
    13621 gattattaca gaagagcttg ggctaatcgg tgcattgtgt gtgcttttct tattgttctc
    13681 attatgcatg agaatctttt gtttaagcag tcgctgtaaa aatcagcaag ctggattgtt
    13741 tcttttagga ttcggaactt tgctattcgt tcagacgata atgaacgtgg gaagtatcgc
    13801 ggggctgatg ccaatgactg gtgtgccatt gccatttgtt agctacggag gaacaagtta
    13861 tctgatcctt tctttaggaa tcggaatcac gttgaatatt tcttcaaaga tacaggccga
    13921 agagttggcg ctctatcgac ctgaaaaaca ataaagagaa actgagaaac tctcagtttg
    13981 aattatcata aagtacaatc ttttattttt caagcgagag gttcttttag aaagaggaat
    14041 tcgcaatgaa agtatctcaa aaaatcatat tatctatttt gttactgctt acattagtag
    14101 ttggctattt ttcgattgag tttatccatg gattttcgtc tgcaaaacag agttcaactg
    14161 tgaaaaaggt agagccgaaa agtatcccta ccacactaaa tgtggctttg attggttcag
    14221 atgctcgttc gaaagacgaa aacggtcgct cggattcact tctggttgca caatacaacc
    14281 agaaaacaca acaagcaaaa ctgatctcta tcatgagaga ttcatatgtc gatattccag
    14341 gttacggaat gaataagata aatgcagctt actcttatgg gggagttgat ttattaaatc
    14401 aaacattaaa ggaaaatttc aaatttgaag ctccctatta tgcaagtatc acatttcaag
    14461 attttatcga ttgcgttaat gaactgtttc ctggtggagt caagatcgat gcagaaaaat
    14521 ctctagattt agatggcgta tatataaaca aaggagagca agtgatggat ggtaatactt
    14581 tactccagta tgctcgattt cgggaagaca aagaaggaga cttcgggagg atcagaaggc
    14641 agcagcaagt gatcaaagct atctctcagc agctgaaaga cgtaacttca atattcaagc
    14701 tacccaaagc ggttgggaaa ttacttggta gtatccaaac gaaccttcca gaaagtgtgc
    14761 ttctggattg tggtatggat ttcctcaaag acatatgtta gaataaacag gtataaatag
    14821 tgaaataaag gaatgacaag caagagaagg aggaaaaaat gaaaagaagt gacaagcacg
    14881 gcaaaaatcg aacaggcgct tatattgccg gcgcagtgat cttaatagca gctgcgggtg
    14941 gcggttattt ttactaccag cactatcaag aaacccaagc agtagaagct ggagaaaaga
    15001 cagttgagca atttgtccaa gctttgaaca agggagatta taacaaagct gcagaaatga
    15061 catcaaaaaa ggcggcaaat aaaagtgcat tatctgaaaa agagatctta gataaatacc
    15121 agaatatata cggtgctgct gatgtcaaag gacttcagat atcgaatcta aaagtagata
    15181 aaaaagacga ttctacttac agtttttcat ataaagcaaa gatgaatacc tcattaggtg
    15241 aattgaaaga tctttcttat aaaggaacat tagacagaaa tgatggtcaa accacgatca
    15301 actggcaacc caacttggtt tttccagaaa tggaaggaaa tgacaaagta agcctgacca
    15361 cacaagaagc agcaagaggg aatattatag atcgaaatgg tgaaccatta gcaacaacag
    15421 gcaaactaaa acaattagga gtcgttccaa gtaaacttgg agatggaggc gaaaaaacag
    15481 ccaatatcaa agcgattgct tcctccttcg acttaacaga agatgctatc aatcaggcga
    15541 tttcacaaag ctgggtacaa cccgattact ttgtcccatt gaaaatcatt gatggagcaa
    15601 cgccagaact tccagctgga gctaccattc aagaagtaga cggcagatat tatcctttgg
    15661 gtgaagcagc tgctcagctg attggttacg tgggagatat cacagcagaa gatattgata
    15721 agaatccaga attaagcagt aatggaaaaa tcggtcgctc aggtttggag atggcttttg
    15781 ataaggatct tcgtgggaca acaggtggga aattaagcat tacagatgca gacggtgtag
    15841 agaaaaaagt tctgatcgaa catgaagttc aaaatggcaa agatatcaaa ttgacaatcg
    15901 atgcgaaggc acaaaaaaca gcttttgaca gtctaggagg aaaagctgga tcaactgttg
    15961 cgacaacgcc aaaaaccggt gatcttcttg cgcttgctag ctctccaagc tatgatccaa
    16021 acaaaatgac aaacgggatc tcacaagaag attacaaagc ttatgaagaa aatcctgaac
    16081 atccattcat cagccgattt gcgacaggtt atgctcctgg atctacgttt aaaatgatta
    16141 cagcagcaat cggtctcgac aacggcacta tcgatccaaa tgaagtgttg acgatcaacg
    16201 ggcttaaatg gcaaaaagac agttcttggg gatcttatca agcaacgcgt gtcagtagtg
    16261 atgtatcaca agtagactta aaaactgctt tgatctattc cgataatata tatgcggcac
    16321 aagaaacgtt gaaaatgggt gagaaaaaat ttcgtacagg cttagataaa ttcatttttg
    16381 gtgaagacct tgatttgcca attagtatga atccagcaca aatttctaat gaagatagct
    16441 ttaactcaga tatcttgcta gctgatactg gatatggaca gggcgaactt ctaattactc
    16501 ctatccagca agcagcaatg tattctgttt ttaccaacaa tggcacactt gtctatccta
    16561 aattgattgc agataaagag acaaaagata agaagaatgt catcagcgaa acagcagtac
    16621 aaacgatcgt gccagatctg agagaagttg tgcaagatgt aaatggtaca gcacattctc
    16681 tttctgcttt agggattccg ttggcagcga aaactggtac agcggaaatc aaagaaaaac
    16741 aggatgtaaa ggggcaagag aacagtttct tgtttgcttt caatcttgat aaccaaggtt
    16801 atatgatggt cagcatgttg gaaaataaag aagatgatga ttcagcaacc aaacgagcat
    16861 cggaactatt gcaatacctc aaccaaaatt atcaataaaa aattgctttt taagtacagt
    16921 aaaaggactg tggcgttatc gtcacagtcc ttttttcaaa taaacggttt tcacgatgtc
    16981 tctttcacaa cttctttttg atttactcac acttcataaa ctttttttgt aaaatatttg
    17041 agaacaagtg gagaaataag tgtacttaat aaaatcacga taactaaagg tgaatagtac
    17101 tgtggttcga tcaattgact ttgctgtcca atttgtaaaa tgatcaaagc catttctcca
    17161 cgcgaaatca taccagcacc gaccatcaat gaactatgtt gagaaaaacc ggcaatctga
    17221 gcaccaaaat aacctccaag caatttggtc aaaatcgcta caagcgtcaa tatagaaata
    17281 aagagtagtt gttcactaaa gtcagaaaaa tcaacttcta atcctacact gacaaaaaat
    17341 actggtataa atactgcata tcctaaagcc tctacattgt ggtatacttc ttctttaacc
    17401 tttgtctgac tgacagctat cccagcaaaa aaagcaccaa tgacagagct aagcccaaca
    17461 agatccgcta cgtaagacat tcctaaacaa ataactagcg atacgatgat aatagaagaa
    17521 tttgcgtaca ctttttctgc aaatgaaagt aggaaaggcg caatccattt gactaataag
    17581 aaaataaaaa caaaataaat tagctgttca atcaaaacaa gcggtaaaga agcattgcta
    17641 gaagcttccc ccgttagaaa agataggctg aaacttagaa ctaaaacgac taaaatgtca
    17701 tctaccacag aagcacccaa aattgttgat ccttcttttg tattcactac gtttagttct
    17761 tttaatactt ctactgaaat actgacagaa gttgccgcaa gaataatccc aaagaaaatc
    17821 gcttcatttc ccgaaacttg gaatgctttg cctgtcaacc agccaaaaac aaccgggaag
    17881 atgatcccaa gcaaagcaac gaacatacca ggtcggaaat attttttcaa aagagataaa
    17941 tcactttcca gaccagctaa aaacattaat aagatcacac caatctccga aaagtcatgg
    18001 actagaatat caggtttgac ccaattcaat ccagcttggc ctagcaaaac accaacaagt
    18061 aattgtccaa tcactgctgg gatacctaat ctccgcgaga tatgtgagcc aatcgttgtt
    18121 gaaatcaata tcaggcataa aataccaata aattccattc tcatcattcc tttgtataaa
    18181 atatagcccg aacttagcat aacatacatt attgaaaaaa taggaaaata tactcacaaa
    18241 aaaaccaaca atccaaaaga tttttttgga ttgttggttt ttatacggtc tattttaata
    18301 actaaaaatg attaacgtat agtcattttt cttattctga tgaaattgat aatctcctgg
    18361 atgcccatga aaatcaaaat aaagccgaat atttggaata gaagcatcaa acttttgaat
    18421 ggattgaaca ataagacgaa tccgccaatc aacaacagaa tactactata aacactccaa
    18481 cttttagctt ttgtattcat gctgaagaac aactggaaca agctgttgat gataacagct
    18541 aatccaagaa gaatcggcag gatagaaacg attgcaggtg caaaagcata gacgatcaga
    18601 gctaagatca ggaaaaaaag accactgaac agaccgatac tccaagaacc tgttttcctt
    18661 ttaaaacggt aagcctcaaa aagattcaac aacccaagca aaacaagata ggcggtgatc
    18721 agataaccga taaaatgaaa aacagcagaa gggtttagca caatcgcaat cccagaaata
    18781 atataaacag cagctcttaa taaggcgtat ttttgaatat tttgtttaat cgtctcaaac
    18841 atataagaaa acctcctttg acttatttta acgtgaacta gtcattttac caaattaaat
    18901 gttacaaaat gagcgaagga gaagaatatc tctggaaaaa tcaacttctg aggatctttt
    18961 ccattttttt gccttttgct agctcatcga tcattttatc taaataacga atttctttca
    19021 tcaagttatc ctcgatgtct tctactcgta caccacaaac aacacctgta atcaaggaac
    19081 gtgaaggatt ggggacaggg gcttccgcaa aaaattgttc gaaagtcact tgtttttgta
    19141 gttgatattc tagttctgtt tgggaataac ccgtcagcca acaaatgatt tcatctactt
    19201 cctcttttat acgatctttt ctctccgctt ttgctacata cataggataa acgcttgcaa
    19261 aacttgtcgt aaaaatacga ttttgcgcca taatcagtca cctttctttt tttcaaatta
    19321 tttactactt atagtatata agaaaaagag aagaaaaagc gattattcaa aaaaacaaaa
    19381 aggattgtga caaaattctt gtcaccatcc ttttttccgc tctctgactt tttacaatct
    19441 tcatagctca agtgcgcatc agataatcga atgctcctaa agctgcagta gctcctgaac
    19501 ccattgaaac aatgatttgt ttgtatggac tatctgtaca atcaccagct gcgaaaacgc
    19561 cggggatatt cgttgcgcca tttttctcgg tcactatttc atttcttgga ttcatttcga
    19621 tcgttccatc tagccaatcc gtattaggga gtaagccgac tagaatgaat actcctgaaa
    19681 cagctagtgt atgcatctcc atcgtacggc gatcgatata ggagagagat tctacctgat
    19741 tcgtaccgct gatttctttc gtcgctgcat gtttgataac agtgacattc gcaagagaga
    19801 ctagtttatc ctgtaagatt tgatctgctt ttaattctgg taagaattct agaacatata
    19861 catgttttgc taacccagcc aaatcgattg ctgcttcaac accagaatta ccaccaccga
    19921 taacagcaat ctcttttcct ttaaataaag ggccgtcaca gtgtgggcaa taagcaattc
    19981 ctttattttt aaactctttt tcgcctggta cattgataga acgccagtgc gcacctgtcg
    20041 cgatgatggc ggtttttgct ttaagtgata taccgttagc taagccaata ttaataaaat
    20101 gttgctcttt atttaaggaa acggcctgtt gattcatcat aatgtcgata gggtaactac
    20161 gcacatgact ttctacttgc tgcatcaatt ttggaccttc tgtgtaagag gtaccaatca
    20221 tattttcaat ccctagtgtt tcaacgactt gtccgccgaa agaatcagcg acaagtcctg
    20281 tacggattcc tttacgtgct gcatagatag ctgcactact agctgctggt ccaccgccaa
    20341 tcactaatac atcataaggt tctttttcaa acaactcttc ttcaatcaaa gggccagtga
    20401 ttttttcaac aatttgttcg atcgtcatgc gtccgctact aaattcttct ccatttaaaa
    20461 acacagttgg cactgccatg atttttttat catcgatttc tttttggaac atcccacctt
    20521 caatcatcgt atgagtaata tttggattta atacagctaa tatattcaat gcctgtacaa
    20581 cgtcggggca attatgacaa gtcaagctaa cataactgtc aaaatgcaat gtttgtgtta
    20641 tttttttgat tttaagactc aaagattcac tgattttcgg tgcccgtcca ctaatttgta
    20701 acatagccag taaaaaagag gaaaattcat gaccgagggg gataccagca aaaacgattc
    20761 cactttcttt gccaactgga ttgatagaaa aactaggtgt gcgcatcgaa tctctttttt
    20821 cccaagagat tttaggagac atttctgcta tttccttcgt aaattcagct agtttttgac
    20881 tattttcact attatccaaa ctaacagaaa aaacaatagg agattcaatc agtgctaaat
    20941 attgttcgag attttgttta gtttctttgt ctaacatatc caccacctaa atctttccaa
    21001 caagatcaaa acttggtttc aatgtttcgc cactttcttt ccattttgcc ggacaaactt
    21061 cacctgggtg ggtacgtaca tattgagcag cgcgaatctt atcaatcagt gcactagcgt
    21121 cacgaccgat tccatctgca ttgatttcca tagcttgaac gattccgtct ggatcaataa
    21181 taaatgttcc tcgctgagct aatccttgct cttcatccaa aacatcaaaa atacgagaaa
    21241 tctgatgaga cggatcaccg atcatcacgt attcgatttt accgatagca tctgatgtat
    21301 catgccatgc tttgtgagta aagtgggtat cggtagagca agaaaagact tcaacaccta
    21361 aagatttcaa tgtactgtat tgttcttgta agtcttctaa ttcagtagga caaacaaaag
    21421 taaaatcagc tggatagaag caaagaatac tccagttccc cataagatct ttttcactga
    21481 cttctaaaaa ttctccttga tgataagcat gtgcattaaa ttcttcgatt tttttcccaa
    21541 tcaatgacat agtaaaacct ccaataataa ttatttattt ataattattg taatttagtt
    21601 ggagttgcaa agtcaatgga tattttgtta tttaataaag attactcaaa aacgaaggtt
    21661 aattataaaa atagaagagg tcgcaagaaa atgctactgc tggaaatact cgggataacg
    21721 ttgagtaaca gtttcctgtt ctttcagcat catgtgtaag tgcaatcccg tttgaaatcg
    21781 agcttcttct ggttttttat caactaaagc cttgagtaaa tcataatgtt gttccatgat
    21841 cgtttcccat ggaagcccct gaatggtcac tcgtaaccag cggaaacgtt ctaaatgggt
    21901 attatggtca tctaaccagt tccaaacttc ttttcttcct gcaatttcga aacaagcttc
    21961 atgaaataaa ttatctgcac ggaaaaaagc gcgttcgtca tttattttga ctgctttttc
    22021 ttgttcttct aaaatcgttt ctagcactat tcgtgtttgt gtgtccaatt tggaacaaca
    22081 ttcaatcatg atttgctctt ccaactgttc tcggacaaag cgagcatttt ctgcagaaac
    22141 aagattaatt ttggaaacat acgtaccact ttgaggtatc gtatacacga gttcttgctg
    22201 acgtagttga atcaatgctt cgcgaatggg agtccggccg atagcaagat gttcctccag
    22261 tgccttttca gatattttcc ttccaggttc taagtcagca tagataattt gtttacgaat
    22321 cgcttgataa gcttgtgatt gcaagctgct tttcatcttt attcctccaa aatcatttct
    22381 atgaacgtag tataacagaa gaggtctgaa aaacaatctg gtatgtcaca ttaactagta
    22441 aatttgtata aatagtaaaa ttttggttga catagcgatt tttattgcat aaaattcact
    22501 tgaatacaaa aactaatatg ttagtttagg aggggaaaaa tgattgattt aaacaactgg
    22561 aggaacttta tccctgaatt atctcaaaaa gaagtagaaa tacctcattt tgaccgtgca
    22621 tcattaagag aaaatggaca aaaaaatcct gtctggatcc atttcggtgg cggaaatctt
    22681 tatcgaggat ttcatgcaga aatcgctcaa cgtttagcgg atctaggcga attgtccact
    22741 ggtgtcattg tttgtgaaac attcgatgaa gaaataattg aaagggctta ccaagatttt
    22801 gatgatttga ttcttgaagt ggtcatgcca agcagtggag agttcgtcaa acgtatatta
    22861 gctgcgacag ctgacagtct gtattgtcat ccagattgtt ctgaacactt tgataagatg
    22921 attcgacact ttgaaaatcc tagtttacaa ttagttactt ttgctattac tgaaaaaggt
    22981 tatcgattga aagatacaaa taataaatat ataggaccga ttgcagtcga tataaaaaat
    23041 ggtccaaaga agccatcaca tacaatgagt attcttgctg tgctacttta taaacgtttt
    23101 ttatctggag cttggccgat tgcacttgtc tctacagata atttttcaca aaacggtagt
    23161 caattacgta cttctttgct aacgatcgca aaagaatggc aaaaggaagg ttatgtacaa
    23221 aatacattta tccaatactt atcgaatgaa gaaattgttg cgtttccatg gacgatgatt
    23281 gatcgtatca ccccgaatcc ttccttgtca gttagcaaaa tgttggcaaa agagggcttt
    23341 tcaaatatgt cgattttcca aaccgcaaaa ggaaataata ttgctccatt tgtcaataca
    23401 gaggacatcc attatttaat catggaagat cattttccca atggacgtcc gaaattcgaa
    23461 aaagctgggg tattcttgac tgatcgtgca acggtagata aagcagatac gatgaaggtg
    23521 acgacttgcc ttaatccttt gcatacgtct ttagctatta tgggttgttt actggggtat
    23581 aggagcatag ctgaggagat gaaagatcca gatttatcgc tgctagtttc tgaaatcggg
    23641 tacaatgaag gcctcccagt tgtggagtct ccaggtatca ttgatccaaa gatctttctg
    23701 gaagaagtaa ttactgtgcg cttttctaat ccaaatattc ctaatatgcc tcagcgaatc
    23761 gccacggata cctctcaaaa ggtggcgatt cgttatggtg agacgattaa aaaatatatg
    23821 gaaatagaag ttaaagaccc gcagacactt gtattcatac cattgactct cgctgcttgg
    23881 cttcgatacc ttattggcat tgatgatcaa ggaaaaccat tcatcccgag tccagaccca
    23941 ctattgacag accttcagca taagctttcc gatattcaac tgggtacgca agatacatca
    24001 catattcatg agaaaatggc tcctattttg tcaaataaag aaatttttgg tgtagatctt
    24061 taccaagcag agcttggcag aaaaatagaa gaaatgttca tcaagatggt agcaggacca
    24121 aatgccgtac gaaaaacatt acaggattac ttacaagaac atggaggaaa tttatcatgg
    24181 aaatgacttt tagatggtac ggatcacagg aagaaaagat taccttagat gaaatcagac
    24241 agattcctgc ggtcaaaggg attgtaggca cattgatgga tataccagta ggagaggtat
    24301 ggcctaggga gaggatcaaa gaactaaaag aagaaattga gtctcgtggg ttaacactaa
    24361 aagtaattga aagcgtcaat gtgcatgatg ccattaaaat tggattacct tcccgtgagc
    24421 agtatatcga aaactataag cagacaatcc gaaacttggc agaatatgga atagaagtca
    24481 tctgctataa ttttatgcct gtatttgact gggtgaaatc tgaccttgac taccgcttag
    24541 aagacggctc atccacgtta gcttttatat ctgatgatat tccagatgat ccaagagaaa
    24601 tcgtcgcgcg catcgaacat tccagcaatg aatttggatt gccgggatgg gaacctgagc
    24661 gcttagctcc tatcaaatcc ttgcttgaag cctatgcatc agtagacgaa gaaaaacttc
    24721 gagaaaattt tgcctatttt ctccaatcaa tcatcccaac atgtgaagag gtaggggtca
    24781 aaatggctgt acatccagat gatccgccat actcgatttt tggattagct cgaatcgtaa
    24841 agaatcgaga agatttagat tggttgtgtc gcatagtaga cagcccttat aacggaatca
    24901 ctctttgtac agggagtatt gcagaagatc cagaaaatga tgtatatggg attttagcag
    24961 aattttgcca aagagatcga atcccatttg cacatgttcg aaatattaaa tttttagcta
    25021 atcgagattt ctatgaggca ccacataaat ccgaatacgg ttcattagac atgtaccgca
    25081 tactaaaaac aatgtatgac aacggattta acggatacat ccgtcctgat catggaagaa
    25141 tgatctggaa tgagacagga agaccaggat acggcttata tgatcgagca ttaggtgctg
    25201 tttatctaaa tggattatgg gaagcaatcg aaaaaggaaa caaaagtaaa gataattagt
    25261 gaaaaaaact gtaattttat tatgtaaata agaaggatgt tcaaattctt gatacataaa
    25321 tccggaggtt gttaataagc attcggattt atgtatctta tttggtctag gaagtaactt
    25381 gattttcttt tttcgattga tccatgagtg cttcttcttt taattcaaag atatattctg
    25441 agatcctcat aatcactttt ttccagtctt ctggtgtgat gattcctttt aaaatataga
    25501 tttttttgat atgagaaggc aattgtttca aagggcagtc gctgataacg atgttgcagt
    25561 tctccataaa atcattttgt attttgatcg attcatttga aaaaatttgt tctatcttaa
    25621 cgatcagatc tttactgata taaaaatcac gcgtatagtt cacaccaatc acaattcgcg
    25681 gctgtttttt gtagcgatca tacaaatgta ctaggtcttc aaccatccat tgcacatttt
    25741 ccttttctaa aataactggt aacaagtgtt gattttgttc tctgaaatcc atataaaatt
    25801 gttcaatggc ggtttggact tctttcaata cgctatgttc ttgataaagc atgaaagtag
    25861 gaaggggcgt atttggttga ttgaagttaa gaaatccatt ataaagttta tttcgtgcga
    25921 atgccaatga gtaaagaatc ttttcttttt caggtataaa caaatcaaat acagtacaaa
    25981 gggactccac catttctctt gaataaagaa catgaggaac gtttgctttt tttaaaagtt
    26041 tgtattgctc caagcttgtt tcttccgatt cgattttcgt gatagaaagt cgagctaaaa
    26101 tattcactaa gatgcgttgt tcgcgacaaa ttggcagatt aggtcgcaaa atatctacag
    26161 agagatcaat aaaaaagtca atatattcat actctgtgaa ttctttttgt acgtctttca
    26221 cagaagttgc aggaaaattc tctttacata tttttaatag aaaatataat ttatctatca
    26281 taccgctatt tagtcggtca agtacttctt ttttaaaaaa agtattcatc ataaaagcca
    26341 ctacttgcgg atcttcatca taaaattctg tagcagtact tgaaaagatg ttccaataaa
    26401 tatctaatgc tgcatattga atttgtacct cttttccaga aaaagacttt ctgccattat
    26461 tagaaaagga gatagacaaa ccgtactatg ctaaaaatgc attaatcttt ttcattttcg
    26521 tatacaaata agaggcacta tagtttgttt gctgactgaa actgataatc gaatttgtct
    26581 gacagctgaa caaagaagtc aagatctgat aactgactga ttcgttgcag tatcttccaa
    26641 atagacgata atagcagtaa gccggatcaa ttccttcaaa attcaacttt aaaaaaggtt
    26701 tttgcttatc aatatgcagt tctgttagat tgagacgctc aaagtcttgt tctaattctt
    26761 tgatgtatag taaaaaattt gattcagaca tatggaaatg atctgctaaa tattgtgtag
    26821 taataaagaa acgatgttca gataggaaaa gaaaaatatc taattttgta ttgctttttt
    26881 tcttcaagat aaacgtttta atcgcttctt gagtttgcat gaaagaggct cctttttact
    26941 taaattgtta aaacttgaaa
//
LOCUS       DAJSMK010000029        25467 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.029, whole genome shotgun sequence.
ACCESSION   DAJSMK010000029 DAJSMK010000000
VERSION     DAJSMK010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.029"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            178..2238
                     /locus_tag="ON488_001260"
     CDS             178..2238
                     /locus_tag="ON488_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HCR3231462.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2321..2890
                     /locus_tag="ON488_001261"
     CDS             2321..2890
                     /locus_tag="ON488_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3231463.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3065..3871)
                     /locus_tag="ON488_001262"
     CDS             complement(3065..3871)
                     /locus_tag="ON488_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231464.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            4009..5523
                     /locus_tag="ON488_001263"
     CDS             4009..5523
                     /locus_tag="ON488_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HCR3231465.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5926..6909)
                     /locus_tag="ON488_001264"
     CDS             complement(5926..6909)
                     /locus_tag="ON488_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HCR3231466.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6914..7561)
                     /locus_tag="ON488_001265"
     CDS             complement(6914..7561)
                     /locus_tag="ON488_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3231467.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7646..8278)
                     /locus_tag="ON488_001266"
     CDS             complement(7646..8278)
                     /locus_tag="ON488_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCR3231468.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8294..8845)
                     /gene="coaC"
                     /locus_tag="ON488_001267"
     CDS             complement(8294..8845)
                     /gene="coaC"
                     /locus_tag="ON488_001267"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HCR3231469.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8842..9579)
                     /locus_tag="ON488_001268"
     CDS             complement(8842..9579)
                     /locus_tag="ON488_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HCR3231470.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9576..10565)
                     /locus_tag="ON488_001269"
     CDS             complement(9576..10565)
                     /locus_tag="ON488_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HCR3231471.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10823..11365
                     /locus_tag="ON488_001270"
     CDS             10823..11365
                     /locus_tag="ON488_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3231472.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     GTFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11382..12467
                     /locus_tag="ON488_001271"
     CDS             11382..12467
                     /locus_tag="ON488_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231473.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12479..13285
                     /locus_tag="ON488_001272"
     CDS             12479..13285
                     /locus_tag="ON488_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231474.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13286..14113
                     /locus_tag="ON488_001273"
     CDS             13286..14113
                     /locus_tag="ON488_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231475.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14110..15183
                     /locus_tag="ON488_001274"
     CDS             14110..15183
                     /locus_tag="ON488_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3231476.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15611..18307
                     /locus_tag="ON488_001275"
     CDS             15611..18307
                     /locus_tag="ON488_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCR3231477.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18384..18872
                     /locus_tag="ON488_001276"
     CDS             18384..18872
                     /locus_tag="ON488_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR3231478.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18884..19378
                     /locus_tag="ON488_001277"
     CDS             18884..19378
                     /locus_tag="ON488_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3231479.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19399..20208
                     /locus_tag="ON488_001278"
     CDS             19399..20208
                     /locus_tag="ON488_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3231480.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20205..21026
                     /locus_tag="ON488_001279"
     CDS             20205..21026
                     /locus_tag="ON488_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCR3231481.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21077..23176
                     /locus_tag="ON488_001280"
     CDS             21077..23176
                     /locus_tag="ON488_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HCR3231482.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            23173..24291
                     /locus_tag="ON488_001281"
     CDS             23173..24291
                     /locus_tag="ON488_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HCR3231483.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24330..25208
                     /locus_tag="ON488_001282"
     CDS             24330..25208
                     /locus_tag="ON488_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCR3231484.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
BASE COUNT         8054 a         4444 c         5393 g         7576 t
ORIGIN      
        1 tacttaacaa aattaaaaag tacataagtt attattccga ttttcttgaa acaataaaaa
       61 atcaaaaaaa atactctcct aatagtccat cttcttttga ttttatttat ataatgaaat
      121 catcttatga aaattactac ttcatgttta gacaagagta gggaggacta agaataaatg
      181 tgttcaaaaa gacgttcaaa acaactaaat aaacacgctt gtcgtttaga taaggaacgg
      241 tcgtgttctg aaaaacacta cgttaagttt atgatgcgca cgatgctgat cagtttatct
      301 gtaggtgtct atatgcatgt acccgttcag gcaacgacac aaaccatcaa ggtcgtacgt
      361 acctctgttt ctgagaccac tgattcccct atcactatta ctcatacttt cactgatgca
      421 aatggaaaac agctacttcc tgcattgact tcctataata aagtcagtta tcctccaacg
      481 ataaaccact actggttaat tcctaacaaa acattatgga catcggaaac cggaagcagt
      541 gtgccgcttt ctatcttttc cgatatgact gatcctacaa aaggtgatca gttaaaacag
      601 atcactgata ttttgaatca tgctttgaca gatataaagg acggtggaag cgcacaagtt
      661 tcttatgtat atgaaaaaga ttattcacag tttgaaagaa agaaaatcga tgttctggca
      721 gggacaaaag tttcgatatc tgatctggta gaaaggctga agaacgcaga tggaacacaa
      781 ggagatatgt ccaaagtaat ttcaaacaat gggaatatcg tggatacgac taatacagga
      841 acatctacta tttccttgtc ctattttgat ccaattgctt taaaaacaat gactgcatct
      901 gctgtgatcc atgttcgtgc tgatcaaaca gctatcaaag gaaaagatct tcacttaaga
      961 acaggagaga gttacgcccc taaagatctt gttgaatatg taacaaaaag cgatggaact
     1021 tcaggaaata aagaagaaat caaaatgaac gggacagtag atactacaac tccgggagaa
     1081 tatcccgttg tattaactta tatagactcg aaaacatcaa atgtggcaga aacaacagct
     1141 gtagtttatg tagaagcatc tgctgcttca tcgactgtca tcactcattt tatagatagt
     1201 caaacaaata aagaacttca agcagaaaca catatgagta gtgtaaatcg tattcctgat
     1261 ttgcgcctac ctgctgaatt ttctgatcga gtgccaaata tagatttatc gacttatgaa
     1321 caaaatggga aagtcacttc tatttctgat tggatgcaag caaacggatt agacagaaaa
     1381 agtcactggt cggagatcct tgaagtactt cactcagaac tgatgaataa taggaagcaa
     1441 tcaggagggg aaattacctt tacttatgtt tatataccag acaatcgttc attagaaggt
     1501 catgatctta ttgttcatcc aaacgaaaaa ataaacaaag aagagttgat ccaatcagca
     1561 acaaattcct taggtaaacc cgtaccgtta aaggatgtat cggttacaat caatgaagta
     1621 ccattggagg atggttattt gaccaaacaa acaggtgatt ttacgattat gtatagttat
     1681 catgacccgt attcactcca agaactccat gctcagtcac tattacatgt tttaccatta
     1741 aacaaacaga tagatcaaaa agaacaaaaa agacaagaag aaagcttgtc agaaaaaaaa
     1801 caacaaatgg ctcatgcagt ttctccaaca gggaaagtaa aacaaacaag aagcctagag
     1861 ttagcaagaa tatctagaaa aatctcagaa tctaataaaa cgataaggca agaagctcat
     1921 ttggccccac aagtttctgg attggaaaat gaaattttag agcctaaaat aaaacaacaa
     1981 tcagaaaaag aatttgttgc taaacagtcg gaagatcaga aggaatcaga tgaccagaag
     2041 gaaacgaaga aaaaacgctt gtcaactatt gattccaccg atgagcatct gcagccgcaa
     2101 gtaccacttc ctagtccggg aacacccgca cctggtggag gtattccttc ttctgcttta
     2161 ggagatttca tgcgaggtat ggcaggaaca tgggtatacg ctaatcgaaa tgaatttgac
     2221 gcagatgact ggttctgatt tatatctcta tctgttatag tcaaataagt agctgagtca
     2281 tatgttattt ggcataatgg agacgaggag ggatagaaaa atgttagata aaacgttacc
     2341 ttacgcagaa atctggatga caagaccact tcaacaaaat gttccaatca cgcctttagc
     2401 ggaaggtttt gaatttcgat tttatcaaaa agaagatgaa tctgcttggg cggagattga
     2461 gacttccgtt ggggaatttc aaacgacaga tgaagcactt gagtattttc aacaaaactt
     2521 tgctccttat cctgaagaac ttgaaagaag gatgtttttt gtagagacaa aaaaaggaga
     2581 aaaagtagca acctgtaccg cttggcgaaa aaaatcaaga gagcaagtgt atccggtttt
     2641 tcattggtta gcagtgaaac cagattacca aggaaaaggg ctcgcaaaag cattgactgc
     2701 cagagtcttg caagaatttc ctaccctcca tacggacgga ccaatctatc ttcacacaca
     2761 gacatggagc catcaggcga ttgctcttta taaaaaaatg ggttttactt ttattgctga
     2821 aaatctagac ggcacaccta atccagatta tgaaaaagtt atgcaggttt taagtaaatt
     2881 agataaataa cgaaatggtg aaataagtcc tcagtattgg gataaaaaac gaaatagtca
     2941 ttcctcatat cttacttttt tgagttaata ctatcggata actaatggca tgccatacat
     3001 tcaaaaaaga aggggcagtg acaaaagtat tgtcactgcc ccttctcttg ttttttagca
     3061 tgttttatcg tttgattttt ttaggaataa aattcttgat gaacgtaaat ttttggtaat
     3121 cgtttcgact atagaggtaa ccaaatacac tgaaaacaac tgctccaata aaattaacaa
     3181 ataaatcctt catagtatcc atgattccca cgtctaagta accattttgg atgattgttt
     3241 tatctgtttt accatctgca ttttgacttt caatgattgt ccgagtgata tctggaacat
     3301 gatagacagt gtttccgtct ttacttaact ccacactatt gatttgctgg atgatcgtat
     3361 ctttttgcat atcgaattgc agtaatttat ctgctgaaaa ttccacaaac tcccacataa
     3421 caccaactgt catcgaaaaa cagaaggaaa caactgctag taataaagga gtcaagttca
     3481 tggtttttgt atttttattg agcaaataaa caagggaaaa gccgacaccc ccagctaaaa
     3541 atccgctgaa tgcatgtaga aaagtatccc acattgaaaa atagccataa aaatcactta
     3601 actctcctaa aactgttgaa ctaaaaataa aagataacaa aatgatttct agcatatttg
     3661 gaatctgtat ctttaatatc ttttccagaa aataagggat ttcaaataaa attaatgtca
     3721 gtaataaaag cattgtattt ccccagtgtt ggttccagac ctgatccact agcataataa
     3781 cgacgatgat acgtaataaa atatagattc cgtttgtgat tctacctgca gtttttgtac
     3841 tgttcgtaaa aaaggttttc aaatgattca taaaataact ccttcatgta tatccttaat
     3901 tatactaaga agcgtgtgtt taccaaagct atatgactta aagaaaaaca gagttgatat
     3961 tgtgaaaaaa atcacttaat atagtataag gagaaaaggg ggatacaaat gaaaaaatta
     4021 gttgctggtt tattaacagc cgttgcactt cttgctatga gcgcatgcgg cgcagatcag
     4081 aaaaatacag cgcagacaag ttctagtacg aaggaatctg ccgaagtatc atcaggcgct
     4141 tctgaacaag tatatacaga tccaaaagaa atgaaagaat cttatgatgt cgtgattatt
     4201 ggagctggtg gtgcagggat ggcagcagct atcgaagcaa aagatgctgg gttgaatcca
     4261 gtaattttgg aaaagatgcc tgttgccgga ggaaacacat ctaaatcatc aagcggtatg
     4321 aatgcttcag aaacaaaatt tcaaaaagaa gaaggaatca aagactcgaa tgatgccttc
     4381 tatgaagaaa cgctaaaagg tggtggagga acgaatgata aagaaatgct tcgatacttt
     4441 gtcgatcact ctgctgatgc ggtcgattgg ctagatcaaa acggtatcaa actggacaac
     4501 ttaacgatca ctggagggat gagtgaaaag aggacacatc gtccgtctga tggctcggct
     4561 attggtggat acttagtgga ggggttattg aataacgtcc atgagcggga aatccctatt
     4621 tttgtcaacg cagatgtgac agacattaag aaaaatgggg aaacggtcaa tgaagtgact
     4681 gtacatgttc aaggagaaga accaaaagag gtcaccggaa aagcaatcgt agttaccaca
     4741 ggcggttttg gtgccagcaa agaatttatt gaaaaatatc gtcccgattt agctgattat
     4801 attacgacaa atcaagaagg atcaactgga gatggtatca ccatgattga aaaattaggt
     4861 ggacaaaccg ttgatatgga taaaatacaa attcatccaa ctgtgcagca ggatgagggg
     4921 gtcttgattg gtgaggttgt tcgcggagaa ggagcaatct tggtcgatca agaggggaaa
     4981 agatttgtca atgaaatgga tacaagggat aaagtatctg cagcaattac agcattgcct
     5041 gaaaaatcag cttatttgat ttttgaccaa ggcgtgcgtg atcgtgccac agctattgaa
     5101 ttttatgacc aaaaaggata tgtcacaact ggaaagacaa tggaagaatt agcagaaaaa
     5161 atcgatttac caaaagaaac actagcaaaa acagttgatg gatggaatac ggatgttgcg
     5221 gagaaaaaag atgctcaatt caaccgtgcc acagccatgg aacatgactt atcgtctccg
     5281 aattattatg cgatcaaaat cgcaccagga atccattaca cgatgggcgg tgtgaaaatc
     5341 aatacgaaca ctgaagtatt agataaagaa aaccagccaa ttagggggtt atatgctgct
     5401 ggtgaagtca caggtggctt acatggaaac aaccggatcg gtggaaattc agttgcggag
     5461 atcattattt ttgggcgaca agcgggcata caagcagctc gatttgcttc ggaaaatgaa
     5521 tgaaatagaa cgtaaataaa aagaggttgt gaaatcagcg ttttgagcta ataccgaggg
     5581 tcagctgatt gaacactgtt tagtgaagag gttgtgaaaa agctgccctg catcaagtaa
     5641 taagaacagc caagtaaaaa cagcttctta tgtttttaac ttggttggac ttattaccgc
     5701 agatgcaagc ttttgaacac cgtttattcg gaaaaagagc gtgggacaaa agtaaagaac
     5761 acttttgtct cacgctctaa acacgtataa acggcggaag cagaagaaat tccttcggaa
     5821 ataagctgaa attcacaaaa atttgaaaag caattttcgt gaatttcttc ttatttcttg
     5881 gagttaaacg cttctgtccc agcctctttt ttgatcagca tgattttatt cagttatctt
     5941 caaaatgatt tttccgatgt ttttgtttgc ttccatatat tcatgcgctt gtttgactgc
     6001 gctgaattgg aatgtacggt caatgattgg ccgaatcttg ccattttcta gaaaaggccc
     6061 agctttttgc ataaaagttt gtgcgagctc tgctttatac tgatcacttc taggtgtcaa
     6121 taatgtacca agcagttgga cacgtttccc aatcaataca ccaaggtcta tctcaggcac
     6181 gatggtccca cctagcatac caatcaagac ccaacgtcca tcaacggcta tagaagctaa
     6241 attcttttcc cagtaagaag cgccgatgaa atccaaaata acatcgactc cccgaccttc
     6301 agtgattttt cgtacctctt cttgaaagtc ttgtttttta tagttgatca attcatctgc
     6361 accaagttct ttacaaaagg cgagtttttc ttctgatcct gcagtaacga tgattttcgc
     6421 gtgagaaagc tgtctagcta attggatcgc tgctgttccc acaccacttg ctcctgcatg
     6481 gatcaagaca gtttcgcctt cttgtaattt tccaagccag taaagtgttt gataagcagt
     6541 caaaaaaact tctgagattc cagcagcaga aacatagtct agcgtatcag ggagaaggat
     6601 tgcacgatcg gcaggcatca cagcatattc ggcataacca cctagattga ctaatccgta
     6661 tacttttgtc ccaggagtaa aagtggagat atcactttta ttctcaacta cctctccagc
     6721 tacttcgact cccaaaatag ggtagggagg tttcaaagag actgattctc ttttcataat
     6781 atctgttcga ttgacagctg ctgtatggac tttgatcagt aattcgcctt gttttggttt
     6841 aggaacaggc acttcaattt gttctaatac atctacagaa ccaggatgct tgattgaaat
     6901 ggcacgcatg gatctattcc tcctttgccc attcttggaa tgctgtattc aactctttgc
     6961 taccttcaga aagtactaga gtcgtacgag aaatatccgt ttcttccact agagcggcaa
     7021 gtacagcagc aactgtagag cgagtgatcg tttttgatgc cttctcatta ggcttagtta
     7081 attgaatgga agtaacttct tcatcgttag tcaatgtgac tggttgaaga atgacaaaat
     7141 ctaagttagt tcgtttcagc cattcatctg cataatgttt agtaatataa taatctgtca
     7201 tggactcagg ccattttgct ggttcatctg cataaacagc actgaccatc agatagcgag
     7261 agacatgcgc attttcagct gcgatcactg ttttgattgc gccatccaag tctacttgca
     7321 gaagattctt tccttgagag ccggcagcaa aaatcaatac atcgatgcct ttgaatgctt
     7381 cggtcatttt ttccacggac caagttaaat caaaagagac atacgaaaca ttctcttttt
     7441 ttactaatgt ttgggaagca acatctctca cccctgcaaa aatttcatgg gaacttggag
     7501 ctaaatcttt tatcaggtgt cggccaattt gtccgtttgc acctacaaca aaaattttca
     7561 tttggatcat cctttcgacg tcaaatcttt ccattcaata gtaacaccaa aagagaaaaa
     7621 aatcagagat cggctacgat gactatcagt tagtaagaga agggtgcttg aagtatctta
     7681 acaagacatt gcatactgct gcagtcgcaa gacctgcgac gattccttca ggtataccac
     7741 ttgtaaaaat aaccgctaga atagctgaat aaacagcatt taaatttgtt ccgatgactt
     7801 tggcataatc ttgctggaat aaaaagtaga tcatattcat cactaaaatc gtattggtca
     7861 atgaaccgga aagtccagct aagaataaag aaacggaatc tgctttttgt ttcattagtt
     7921 tgcgcagacc tttataaacg aaataaggaa ccaccccaat caagatgcga ggaataaacg
     7981 cgatcagcaa ggctttccag cttccatgtt ctgttccgat gactgggata aacggagaaa
     8041 agacaaaaga caaaggtgtt tggataactg tgctacggat catgctgatc agtccaaatg
     8101 taccgccaag aaaagcacct agtcttggtc ctaaaacgat cgaagcaatg attacaggaa
     8161 tatgcatggt tgttgcattg attggaccga tagggataaa acctaaaggc gtaacagcta
     8221 ataaaatcaa aatagctaaa aacatcgcag ttaatgtaaa gttttttgta tttttcataa
     8281 gtactccttt tttctaagca tttctttcat taagagtcag catgacctgt tcgatgatcg
     8341 tctgaatatc agctaaggca ccttttccaa aatctccaca agctaaaaga gattctcttg
     8401 gttcaatttc ctgatagccg acagatctca atgtttccag attacgctga gtgatcgggt
     8461 tttgatacat attcgtgttc atggcagggg caatcaattt tggtgttccc actggaagcg
     8521 ccattgcgac tgttgaaaga agatcgtctg caatgccgtt tgctagcttg ccgataatgt
     8581 ttgctgtagc aggcgcgatg agaaacaagt cagcttgttt tgctagttcg atatgattga
     8641 ttacctgcgg atttgattct tgcatgacgt ctgtatggac tgcgcgcttc gacagagatt
     8701 gcaaggttaa tggcgtgata aaatgtgtgc tgcttttaga cataatcaca tctacctggg
     8761 cacctaattt gacgaattga cttgtaagat cagcgctttt gtaagcagaa atacttccag
     8821 taacgcctag taagatcttt ttcattttga ttcctccagt ctaattttct cagtaatcaa
     8881 tgcagcaatc tcagatttac tttgagcttc ttccactgtt ccatctttag ataagagata
     8941 gccgtggtgt gtctcgccat ggatttccgt caaatcattt gcgaaaataa aatcagtttt
     9001 gttatttatc agactatttt ttgcgactgc cagaagagat tcctttggta catctactaa
     9061 tagtttgaaa ccaatgattt ttgcttttgg ctgccattca cgtagataag aaatgatttt
     9121 tggtgttttc ttcaaaacga gcacaagatg ctcggtgtta gaagagatct ttgaaacagt
     9181 ggtatctgtc tgttcatttt ccgcaaacca attgtccagt tcttcttgcg ttgaagaagt
     9241 gggtaggttt tttgccagct gttcttctga aaaactaaaa gcaggagtaa aatcactgac
     9301 tgccatactg tggataatcg catcgtagtg ttcttttttc gttagttctt ctaattgtaa
     9361 aaataagtcc agtgcagatt cgatcgtata aatcgttata ttggagtgtc ttttcggttt
     9421 cagtgcttgt ttcgtagtca cgtaatcgat tgtggtatcc ggattggcag ctaaataatc
     9481 agctaatgct tgccctaatc gtcctgtcga atgatttgta atagcacgta cttgatcgat
     9541 tttttcagtc gttcctccag ctgtgattag aatcttcatt tatggtcacc tacatttact
     9601 agtgttcttc cttggtgtgt tccagcaagt agtttagatg ctgtttcagg caattgatcc
     9661 agagtaatct cttggacgac cagttcatct gcaatctgca aatccgccat ctgttgccat
     9721 aaagaaagac gttgatctat tggtacattg acagaatcaa ttccaatcaa ctggatgttt
     9781 cgcagaataa aaggcaagac agtcgcgttt agtttgattc ccccagcatt gccacataaa
     9841 gctactgcac cgttataaga gatcaatgga agaagactgc ttagctgctc gccacctact
     9901 gtgtcgatga catagtcgat ttgctgtttt cctaaagctt ttgttgtctc tggcagaaat
     9961 tcatcaggtc gtacgacttg caaagcacct agacttttta gccatgtgac agactcttct
    10021 tttctggaaa aggcaatgat tgactggaat cctagtttat gtaacagggc tatcgctgta
    10081 ctgcctacac cgccagaagc accagtaacg acaacttttt tatcggaggt cataccttga
    10141 cggattaaag cgttcacaca caacatagca gtaaaccctg ctgtaccaag gatcatcgct
    10201 tgacgcagcg tcatattttt tggtagagga actaaccagt ctcctggtac tttttgatat
    10261 tggctataac cgcctggatg ggtgacgcca agcccaaaac cagtagcaag tacaagatct
    10321 tcttttgaaa aacgtggatt gttactttgg acgacagttc cggataaatc aatccctgga
    10381 gtcatcggat atgttcgtat cacctgacca gactcgctca ttgccaatgc atctttataa
    10441 ttgacatcag aataggcaat ttttaccaag acttcatttt cagccaactc agtaaatggc
    10501 agatcactga ttgctgtatg gaaaacaggt tcctttatta cctgaaaaga tcgaaaagcg
    10561 ttcattcgtg agacactcct tttaaaattt tcttttatca taccataaag cctactcttt
    10621 tattcttgtt cttccgtaaa tttagacaaa aattaggtga aaaataaaga atcaaacaac
    10681 tagaatttat tccaaaagat aaagaaatat tcagcaaaaa aaattttaca aagggttgcc
    10741 tttttcaata aatttcgtat actaatacga gtggtagtaa acaggaagtt tactattaga
    10801 aaacttcgat tcggaggaaa ttatggaaat tggtgagaag ttaagaaatt tgcgcatcca
    10861 aaagaatttg acacaagaag aactaggcga acgcacagat ttgtcaaaag ggtatatttc
    10921 ccagttggaa cgagatttaa gttcaccatc aatgggaaca ttcttttcta ttcttgaagt
    10981 cttaggtgtg actccagaag aattttttca tcaagaagca gcgaatctgc aagtggttta
    11041 ttcaaaagaa gatcatacgg tttatttcga tgaagaaaac gggtatgaat tggaatggct
    11101 cgtggctgat tcgaatgaaa aagaaatgga gcctgtcttg ctgacttttg aaggtgcagg
    11161 agaatataag acgtttgaac cttcattatc tgaaacgttt atttttgtat tagaagggga
    11221 attagagtta agcttaggag agacggtcta tgtggcaaaa gcaggacagt cgatctatta
    11281 tcaagcgaca aaacaacatc aattaaggaa tcatctcaaa aaacgaacaa aagtattgat
    11341 tgttgcaacg caatcatatt tgtaatatag ggggtaaaaa cgtggggaaa ccaatcattt
    11401 catttgatca agtagtgaaa cgctatgatg atgaaacagt attaaaaaaa gtaagttttg
    11461 agatcgaaca aggaaaattt tatacactgc ttggtccttc cggctgtggt aaaacaacga
    11521 tcctacgtat tatagctgga ttcaccgaag ctacagaagg ggacatctat tttgaaggga
    11581 aacggttgaa tgatttgcca gctaataagc gacaagtaaa tacagtcttc caagattatg
    11641 cactttttcc tcatatgaat gtttttgata acgttgcttt tggattgaag atcaagaaaa
    11701 tgtccaaatc agatatcgaa aagaaggtaa aagatgcttt gcgtatggtc cagcttcctg
    11761 gatacgaaaa acgggagatt agtgaaatgt ctggtggtca aagacagcgt gtagcgattg
    11821 cacgagcaat tgtaaatgaa ccgaaagtat tgctattaga tgaaccgtta tcggcgcttg
    11881 atttgaaact acgtacagat atgcagtatg aactgcggga tctgcaacaa cgattaggaa
    11941 tcacgtttat ttttgttact catgaccaag aagaagcgtt ggcaatgagt gatgagattt
    12001 ttgtcatgaa taaagggaaa atcgtccaaa gtggtacacc cgtagatatt tatgatgagc
    12061 caatcaatca tttcgttgct gattttgttg gggagagcaa tatcgtggac ggtgtaatga
    12121 tcgaagataa tctagttgag tttgttggta agcaatttga atgtgtcgat ggcgggatgc
    12181 gtctaaatga accagttgaa gttgttttac gcccagagga tttgacgatc acgacaccag
    12241 ataaaggaaa actagtcgta acggtcgata ctcagctgtt tcgtggtgtc cattatgaaa
    12301 tcatctgtta tgatgaacag caaaatgaat ggatggtcca ttcaacgaaa aaagctaaag
    12361 aaggaagcaa agtaggattg gcctttgagc cagaagatat ccatgtcatg cgtttcaacg
    12421 agtctgaaga agaattcgat gcacgtcttg acagctacga agaatagggg ggacaagaat
    12481 gaaaacaatg cgcaggatct attccgtccc ttatattttg tggctcggtt tattcgtgat
    12541 cgcgcctgta ttaatgatca tttatcaatc tttttttgat atgaatgggc aattcacgct
    12601 gaataattat ctatcttatt ttacgtcggg gacatcgctt tctatgacga tcaattctgt
    12661 atggtatgca tttttgatca cgtttttcac gctgatcatc agttacccga ctgcttattt
    12721 tttaacaaaa ctgaagcaca agcaattatg gctgatgctg attattttgc ctacatgggt
    12781 gaatctgctg cttaaagctt acgcatttat tgggattttc agtgtgcacg gcagcgtgaa
    12841 tcatttcttt gattttatcg ggatcgggcc gaaacagata ttattcacag acttcagttt
    12901 tctgttcgtg gcaacgtata tcgagattcc atttatgatt atgccaattt tcaatgcatt
    12961 ggaagagatg aatccttctt tgatcagtgc tagtagagat ttaggcgcga atagctttga
    13021 gaccttccga cgagtgattt ttccgttatc attaaatggt gtgaaaagtg gtgtccaagc
    13081 agtatttatt ccttctcttt ctttattcat gctgactcgt ctgattggcg gaaatcgggt
    13141 gatcacttta ggaacggcta tcgaacagca tttcttggtt acacaaaact gggggatggg
    13201 ttctacaatc ggtgtgattt taatcattgc tatgttcatc gtgatgctcc tgacaggcga
    13261 gaagaaaaaa ggaggtcgct cataaatgaa aaaatttaaa tggtcgtatc tttatttagg
    13321 gatcgtcttt ttattcttat atgcaccgat cttctatctg attttttatt ccttcaatga
    13381 aggaggaacg atgaacagct ttacaggatt tacttgggaa aattatgaag ctgtttttga
    13441 agatacacgt ttgatcatta tcgtattgaa tacgttcatg ctggctttct tatctgcatt
    13501 gatcgccacg atcatcggga catttggggc tatgggaatc tattacacga aaaaacgacg
    13561 tgcacggaca gcgttgttga gcatgaataa catcttatta gtctctcctg atgttattat
    13621 cggtgctagt ttcttgattt tctttacact actaggattc ggattaggtt ttcagagtgt
    13681 attgctttcc catattgctt tcagcattcc aatcgtcgtc ttgatggtct tgccaaaatt
    13741 gcaggaaatg aacgattcaa tggtcgatgc ggctagagac cttggtgcta ataatttcca
    13801 agtagtcaaa aatatcattt tgccttatct ttctccagga atcatagctg gatattttat
    13861 ggcatttacc tattctcttg atgattttgc ggttacattt ttcgtcacag gaaatggctt
    13921 tacgacgctc tcagtagaga tctattctcg tgcaagacaa ggaatcagtt tagaaatcaa
    13981 tgcgctaagt gcgttagttt tcttgttctc catgatattg gtcattggat actactttat
    14041 tagtaaagaa aaccgtccaa aacggctgaa gaaaaacaga agagtacgcg agggggtggc
    14101 acggctgcga tgaaaaaatt acaatctctg tttttaggta ttctcatcat tattgcggtg
    14161 ctgctgcttg gtgttcgtca acttgaaaaa acaagtggca tgagtggagc aaaggtactt
    14221 accatctata actggggaga ttatatcgat cctagtttga tcacgaaatt tgaaaaagaa
    14281 tatggataca aagtgaatta tgaaacattt gattctaatg aagcgatgtt cacaaaaatc
    14341 cagcaaggtg ggacaaacta cgacatcgct ataccaagtg aatatatgat ccaaaaaatg
    14401 atcaaagaaa aactagtact tccattagat cattcgaaga tcaaaggatt aaataatatt
    14461 gatccacgat ttttagactt ggattttgat ccagataatc agtattcgat tccatatttt
    14521 tggggaactt tagggatcgt atataacgat aaattctttg atgcaaatca aattaagcat
    14581 tgggatgatt tgtggaagcc ggaattaaaa gacagtttga tgctgattga cggtgcacga
    14641 gaagttatgg ggctttcttt gaatagttta ggctattctt tgaatagtaa gaatatggca
    14701 cagctgacag aagcagcaaa taaattgaat catttaacac caaatgtcaa agcaatcgtg
    14761 gcagatgaga tcaaaatgta tatgatcaat gaagaagcct ccgtggcagt gacattttct
    14821 ggcgaagctg ccgatatgat gtgggaaaat gaacatttac attatgtgat cccaccagaa
    14881 ggatccaatc tttggtttga taatatcgtt atgccaaaaa ccgtgaaaaa taaagaaggt
    14941 gcctatgatt tcatcaactt tatgctagaa ccggaaaatg cggcacaaaa tgcagagtat
    15001 attggttatt ctacaccaaa tgaagaagca aaagcgttat tgccaaaaga catttcgtcg
    15061 gacgaacaat tctatccatc tgatgacacg atctcccatc ttgaagtcta caaagatcta
    15121 ggatcgaaat acctaggcat ctataatgac ctattcttag aattcaagat gtataggaga
    15181 taatggcaaa actcagtaag aatggggact tatcaacgtt ctaaagagct aaaaatcgtc
    15241 ctttttctat ctgagttttc caatcttcta ccaaaagcgg atgaaacgcc gctttttttg
    15301 tgttatttta ttttttctac cacgtttttc taccagagaa aagtggacaa aaccattgta
    15361 aaatagggcc cgagacgggc tagtaaatct aagattgaaa aagttacaga aggataaagt
    15421 aattggaaac tatgcaaata tacttaaccc ttctgtaatc tattaataaa actaatatat
    15481 gaatccagtt caatatttgt agctatgaaa aaacataaaa atcatattag ataaaaacta
    15541 aattggtaga taaattattt tgtcagatat ctgaggcaaa tattcgacta tttgtgtttc
    15601 aaagtaaaaa ttggaataca aatatagaat agacatattg cagccgatag tttattatgc
    15661 ttttagacac attaaactgg aggaaaaaat gaaaaagagc gctaaagatc gagtttttga
    15721 tgagctgata cgactaacag ggaatatgtc ttctgtcact gccgagaaaa tttcgaagaa
    15781 tctaggtatc tctcgtcaga atgccagcca ttatttgacg agattagtgg aagataaaaa
    15841 ggtcgagaaa ttaccgggaa agcctgtttt gtggaagcct ttagatgaat atgcggttgt
    15901 agataatacg gagcaaataa acgaagcctt tcattctgta gttggtcatg acggaagtct
    15961 gagagaggtc attcaaaaat gtatagccgc tgtcaaatat ccgcctaacg gactcagtgt
    16021 attaataaat ggagccacgg gtgttggaaa aagtttttta gccacaaaaa tttttgaata
    16081 cgctatccat gagcaaatta ttgaaaaaga tgcaccattt gctatcttaa actgtgccga
    16141 ttatgcggac aatcccgaac tgctttcggc aacactgttt ggatacaaga agggggcctt
    16201 tacgggggct gaaaaggata ccgatggttt attggcaacg gccaacaacg gctatctttt
    16261 tctcgatgag gtccatcgcc tatcgaaaga aaatcaagaa aagctctttc tatttattga
    16321 tactggaaac tatcgtccag tcggtgaaaa tgtaaattgg cattctgcta aggttcgttt
    16381 tattttcgcc acgacggaaa aaggtgaaaa ttatttatta gacacctttg atcggcgtat
    16441 tcaaattagt gttatgttgc caacttttga agatcgcccc attcgagaac gattagagct
    16501 gattcaatta ttttttcaaa atgaagcgga tgttttacaa aaagatatta ttgtttcaag
    16561 agaagccttg tctttaatgt tatctcatcc ctttagtggg aatattggta agctgaagaa
    16621 tatcattaaa atcagttgtg cggatgtgta tagtcgaaca caagaagaac cattaacgat
    16681 tgggaaaaat gagatcttga ttcagttaaa tatgctggaa tccgaagtag aaagcttgcc
    16741 gattgctagt ttattgataa agaaaaatca aaagataaaa acggatcgaa tcaaaccgtt
    16801 tgattatgat tcgattttgg aaaaaattac tcagctgata aatgaaggta atttcaatga
    16861 aaatttttct tcgataaaga atgaagtaca gcatttggtg catcacattg ataaggattc
    16921 ttttttatca atgagtagaa aattgatgat tcagatgttt agaaaggtct gggtatccgt
    16981 tttaggaaaa acgtacggat tgacgacgag tggacctgtt gcagaaatta ttagcagatc
    17041 ctatgtcatt tccccaagct ataagacaga cttaaccggg ataaatcgta cattagctgc
    17101 aaatctacct cggacgactt acttatgtaa tcagttcttg gagcatttac caccgctctc
    17161 agaaaaggac gagaactttc taagactgct tattgtcgtg actttatctg attatgtaga
    17221 tgaatccatc gagctgaagg gcctgttgct tgctcacgga gatagtacgg ctagcagcat
    17281 tcaagcagta gtgaatcaat tatgcggcaa ttatgttttt gaagcgttgg atatgccagt
    17341 agagagtaat gtgtcagaga ttgtcgaatc gacaaggaat ttcgtgaaac ggcaagtgaa
    17401 tacagatagt ctagtgctga tcgtagatat gggctcttta aatcaaattt acacacagat
    17461 caagaacgat ttaaaagggg agttacttct tctgaataat ttgacgactt ccattgcact
    17521 tgatattggc ttgaagatga cgatgaatgc gccatttaaa cagattgcgg aggatgcagc
    17581 agacaagtat tcaatcaatg ttcaatactt tgaaggcttt tctcaaagta gcaacattat
    17641 catttcctgt atgtcgggtt tggggatttc ggacaaattg aaagatgttt ttcgtcatca
    17701 tttatcggat gaatccatcg aagttttcac gaaggactac agagaactac gtgaattaat
    17761 cgaccaaaat gatgaaactt attttgacaa gacaaaattg gtcatcacga cttcggatct
    17821 tccacgttcc ttttcaattc ctaatattaa tgtttatgac atcttagacg gtgatggagc
    17881 agccaatttg gagcatattt tgagtcctga aatgaagccg gcagaattta accgcttgat
    17941 tcaggagcta gtaaaattct tttcgttgga aggaattgcg gaccgtttga actttctgaa
    18001 cccaacgatc gtgatgagtg aagtggaaac agtcatttct aaatatgaaa attactatca
    18061 tttcacttta aatggccgtg taaaactaaa tctctatatg catacggcat tgatgatgga
    18121 acgtttattc ttggctcgga cagaaaaatc tgaagaaccg aattatgatt tgaaaccaga
    18181 tgaagatgaa ttttattatg tttctagaag tatttttcaa tcaatggaga tgaaatataa
    18241 ttttaaagtc aatgcttatg agctttcgct gctctatgaa ttattaggac cgtatattca
    18301 aaaataaagt gtctaaaaaa gtgtctaatc tgtttttttt aggttagaca ctttttttaa
    18361 tgtgaattaa cgtgattaaa ccaatgtttt taaaagttgg cacaggaatt gcttatataa
    18421 aagtgaacag aaagaaagga attaaccata tgaagaaaat tctaatagcg actcacggtc
    18481 acttagcttc aggctttctt agcagtattc aattactgac ggggaaggtt caagagatta
    18541 cggtgattaa tgcttatgtg gatgagtgtg attttgaaca ggagttgaat gtatttgtaa
    18601 accaggtgaa cgagcaggat cagatttttg tttttaccga tttatttggc ggaagtgtca
    18661 atcagaagat taccaaaacc tttttggaga aagagattgc tgtaactatt ttgtctggct
    18721 ttaatctgcc aattctgctc gaaatagtat tggcaaccaa ggaattaaca aaggaggata
    18781 ttcaggaact ggtaaataaa tgccaacagg aattaaagat gaccattctt gatgaggtac
    18841 atgtagtaaa tgaagaggaa gatttttttt aggaggaaga aaaatgatta aagcagtgcg
    18901 aattgatgaa cgattaattc atggacaagt agcgatgact tggacaaaga gtctaaattt
    18961 aaccgggtta gtagtagcaa gcgatgaggc ggctaccaac gatattcaaa agatgacatt
    19021 gaagatggct gcaccatcga atgtcaaagt cattattaaa acagttgatg acgcgattca
    19081 tttgttaaaa gatccgcggg cgaaggacat gcgcttgatg gttttagtcc ctaatgtcaa
    19141 agatgcggta aaagttgcga aagctttccc aacggaaatc gaattaatga acgtggggaa
    19201 tgctgggaaa atgacaccgc catcggaaga taagaaaacc ttatcaaagg aagtgatgtt
    19261 aacgacgtca gaaattcaag acttaaaaga attagttgaa ctttatccag ataccgtttt
    19321 tcagcctaca ccggcgatgg aaaaacgttc agctatctct attttgagtg atttttagaa
    19381 aaaggaagga gaaaaattat gtatgatgca tttgtagtcg ctttggccgt ttttattgga
    19441 gttgctggac atgaaatgtt cgggatgtcc atgctgagtc gtccgattgt tgttgctccg
    19501 ttagcaggag cgttgatggg ggatttgcag acggggttga ttgtcggggc gtcactagaa
    19561 gccatcttta tgggtgtcgt caatatcgga atctctagta cggcggagcc ttctttggct
    19621 gctgggctgg ctacagcgtt cgcaatcaaa atgggaggaa acgtggatgc gattattccc
    19681 attgtctttc cactagcagt attaggatta cagttaatga atatgatttt ttcttttgta
    19741 tgtggaccga tggctgctaa atttttcaaa tttgcaaaat ctggtgatca aaaaggaatc
    19801 atcaatctgc acttctttat gtggtttgtc cactatgcgc tttatgctct tattccattc
    19861 tttgccgttt tatttggagc agatgttgtc aaaagcgtct tggataatat tccagaggtc
    19921 atcatgaacg gattaacagt cgctggaaat ctgctgccgg cagttgggat ggcgatgctg
    19981 ttacggatgc tttggagtaa aaatattgct gtgtggtttt tctttggggc cgttgttatg
    20041 gcgtatctcg agttaccatt gattgcaatt gccgcagttg gaacgattat tgcaattgtt
    20101 atagcccaaa gagatctaca actaaaaaat atatctgttc atgcagttca aagcgatgct
    20161 gctgtaaatg caacgcttga ccaagaagag gaggatttct ttcaatgaaa ttagctgatg
    20221 gaatttctaa agatgagaaa aaattggttc ggaagatgtt ttggcgctcg atgactatgt
    20281 atgcttcggt gaatccggtg acgatgggcg gcggtggttt cgcctattct atgatgccct
    20341 tcattaatca tttctacaaa agtgaagaag atcgagctgc ggcgctggaa cgtcatacac
    20401 agtatttttc gacgaccatt ccttgcgcgt cctttgtcat ggggattgcg gcatcgatgg
    20461 agaaggaaaa ttctgaaaaa gctggttttg acgtggaaag tatcaacgcg atcaaaacga
    20521 gtttgatggg accattggct ggaattggcg attcattgtt ctggggagtt tggcgtgtcg
    20581 ttaccgcggg actagcgatc aacttagcca atgccggaaa tattttggca ccaattatct
    20641 ttttagttat gttcaatata cctaattact tgatgcgata ctatggcggc gttttaggct
    20701 attcattagg ctctaaatat attgaaaagc tgtatgcgaa cgggttaatt gaaattctga
    20761 caaaagctgc tagtatcttg ggtctgatca tggtaggtgc aatgacgatc agtatggtca
    20821 aattcaatac cgttttgagc ttttcaatga agggcgaaga actaatgaat gtccaagaaa
    20881 tcctcgatag tatttttaaa ggaattgtac cgttattggt aacattgagc tgtttcaaat
    20941 tactagataa aaaagtcggc gtcatcaaaa ttatttttgg aatggtcgtc ttgggaattt
    21001 tattgtcatt acttggaatc gcatagtagg aagctgcagc tactaggctg cagttttttt
    21061 agcaaggagg gaaaagatga ctattaatga agtaatttat tcacccaaac acccattttt
    21121 taatgctgag ttaaacgacg gaaatgtgac tacttcaaac gaatacagct actatcggaa
    21181 tattcctgat gtaaagggat tgaccttcga tgtaagtaat caaaagacat tagcaaacct
    21241 tgatgtttgc gggacgattc aaacgttgac cttttatcga gaaaatttac taactgagga
    21301 aaaaccaggt gtttgggtca ataaacagct ctctcaaacc aattcgttat ccttaaaggt
    21361 tgaagtaaac gggattgtct accatttgtc agaatcggat catcgtattg aagtcgatgt
    21421 gattcaagac tgtttgccta gatatattca tcattattcg acgtttaagg tcattgtagt
    21481 atcctttgct cccatactgg ctaataagcg tttaagtatg cttgttcaac aggtttacat
    21541 tgtgaatgaa acacacgaaa gccttcaagt ttcagtgaaa gatgtgcctt cgtatcaaga
    21601 gaagtattcg gatcagcaaa atgtgttgat ttctcaaaaa ggaaataagg acacgatcgc
    21661 acaacaggaa gtggcaagct tcgccattgc ttttgtggac ccaaatgctt ttgaagaagt
    21721 aatgactttt caggaatctg atatcgaaaa atggctgaag gaaacattga actattttgc
    21781 tcagctattt gggcagctgt caatgccaaa cgatagagtt gtccatctct atcgtcgtgc
    21841 actttatcaa agcttttcta gtttcggtat gaatcgacag ggacaggtcg tcggcagcaa
    21901 ttggggcagc tatcctgcta ctaatcgaat ttggaataag gatatgtatt acgcatcatt
    21961 gccattcacc atgtttgaac cggagttatg tcaaaaaacg gttctatggt ttgatcaata
    22021 tggcgttaag tttcctggtt caaaatttac aggaggtatc aatcattctc tgagtaattc
    22081 gttatccagt gcgttactgg ctagtcttta ttttgaacat actggggata caaaattctt
    22141 tgagcggtgt ccgcaggttc tactgaatgc ttcaagaatt attgaggaca tattagctca
    22201 acgtcggtca ggggaaccaa tgctttttcc atctgtttgg ttatcagacg cctttgcact
    22261 tggaaagtat cataccggca gcaatctttg tctttggaag gcctgtattg gacttgcaga
    22321 aatttttgaa gccctagaac aactgagtct tagcaagcga tacaaaaaca ttgcctgtaa
    22381 actaaaggaa tcaatttgta aacaaatgac tatcgatggt ccttttggtg agcaattttt
    22441 ggagggaatc ggtgatgagg agaaaacaac ctattcagtg aagcactatc aaaaaccgat
    22501 tcttgagcaa gggttaatct ttttaagtga tgtgattgtg gatggaaaaa ttaatttatt
    22561 gatgcatgat ggagaagaat cagacactac gttgatgcct ttttatcaat ttttagataa
    22621 taaagatcat ttatatcaga acaccatggc cttttctgct agttctttca atccaaccta
    22681 tagcgaggaa atcaaaggca tcacttgggg attagaatcc ggcgccactt ttcctggctt
    22741 tatcactgtt ttaatgagcg agctgcacaa ccctcaagct ttcgtaaccc gattagaaga
    22801 actaatttgt ttggcagatt tagacggttc gtggtggtgg tggccgtatc gcttagaggc
    22861 tcaacaagga gaagtcgtgc gagactttgg ctgcggcaaa tgcggctggg catcgggtct
    22921 ttttgtcagc ctaatgatca gtcaatattt cggattgaaa ttcaaaaaag gagtattgca
    22981 aattgatcct gttgataatt taacgttttc ttggaagaat ttgaagttcg gtcaagcctt
    23041 catttcgatt gaatgtacgc aatccgagtt gagtatttca aatttgtcag aaaagccatt
    23101 gaaaataagt gatacgaaaa aaattcttca cgtagaaaag ggaaaaacga ttcacattca
    23161 aaggagaaaa agatgagtat actaaaaaat attacccaat ttaaaaaaat ccagagtcga
    23221 gcaatcactc ccgaaaatcc aacaggcgag aaaggtaaag ctgcgatgtt gccaagcgag
    23281 ctaggaccaa gccgcaaagg tcgtggcgca attccgctga cttctggtga agaaactgtg
    23341 attgcggata ttactggaac gggaataatt cgtcatatgt ggatgacgat tcgtgatcga
    23401 acagaatttg gcagttttgt tttacgtgat ttaatcttaa gaatttattg ggatgggtcg
    23461 gatagccctg ctgttgaaag tcctttaggg gatttctttt gtaatgggtt tggagagcgt
    23521 tgcgaggtga actcgttgcc gatagtggtt aatcctacag ggggctttaa ttcctatttc
    23581 gaaatgcctt tccaaacatc cgctaaaatt acgatcgaga atttacatcc gaaggatatg
    23641 tcctcatttt tttatacgat aaattacgct ttggtggacg aattggaaga aaatagccta
    23701 tattttcacg caaattggca tcgggaacgc attaccaaat tacaggagga ttataagtta
    23761 attgatcgat taaagggtca aggctattac gtgggtactt accttgcgct tacctgccta
    23821 gaacgttatt ggtggggcga aggcgagttt aaattctaca ttgatgggga tagtgagtat
    23881 ccgaccgtaa cctcaacagg ttcagaagat tattttggcg gggcgtgggc ctttcatgag
    23941 tacgatgagt tcggacgtcc acatgcgaaa aactattcaa cagccttttt agggtatcct
    24001 taccaatcaa atagagatgc cacaagagat cgttttgaaa cgggaaaatt gaatgccgtt
    24061 catgcctttg gtgacgacgc aatgccacga catggtcttt atcgttggca tcttcaagac
    24121 cccatctgtt ttaccgaaga tttatcggtc actttacaac aaatcggcaa cgatgatgtt
    24181 cgcttatttg agcggcaaga cgatgttgct agtgtcgctt actggtattc aacagaagct
    24241 tcaggaaata ctaaacgtca tttcactgat cgagaacgct tgccgcgtta atgaagtgtt
    24301 tttcacatat tcgaagggag gaacctatga tgatatatgg ggcaattgaa gctggaggga
    24361 ctaaatttgt ctgtgcagtc ggtactgagg aattaacgat tttggaaaga gtcagttttc
    24421 ccacaacaac tccagttgaa acaatgaagc aggtcattga tttttttaaa ccttttaagg
    24481 aacaattggc aggcatcggg gtcggctgct ttggtccaat tgatattcaa tgcaaatcaa
    24541 cgagtttcgg tcatatcaca tcaacaccaa aacttgcttg gcaaaatttc aattttgtag
    24601 gaacgctaaa gcaatatttc aatattccga ttgaatggac aacagatgtc aatgcggctt
    24661 gctatggtga atatgttgct ggttctggca aagggttagc aggtgttgca tacttcactg
    24721 tgggaacagg tatcggaggt ggtgccttgt tcaatgggac tttcgtggaa gggttcagtc
    24781 atccggaaat ggggcatatg ttgatcaagc gacatccaaa ggacaatttt tcaggaaact
    24841 gtcccttcca ccaagattgt ttagagggga tggcagcagg accagcgatt gaaaaacggt
    24901 tgggtgtaaa aggccagaat ttattggctg acgattcgtt ttggcagatt gaagcctttt
    24961 accttgccca atgtgcatac aatacaacac tgatgttttc gccagataga attatttttg
    25021 gcggtggtgt aatgaaacaa gaacacatga agaaaaaagt tcaggataaa tttgttgagc
    25081 ttataaatgg atatgttgaa ataccaccaa ttgatagcta cattattacg cccgaattag
    25141 gtgataatgc cggaataatc ggcggattag cattggccag aaaagcggta agaaataagc
    25201 aaccataatt aatgaatgtt tcattgatac tcatgtcaaa agtatttaac cgagtaatca
    25261 aatgatcaaa tgaagttgga taaagcgaaa atgaattcaa ataaaaaggc tctaagtcaa
    25321 atcgtgttgt tttcattaaa tcactgaaag gaaatgcttc tgcgtttcct tttttctttt
    25381 tgttgtgcgc tgtatacctt gaggatattc actggtggcg tacacttaaa tagtaatata
    25441 ttacccgtgg tgctagttaa ttttttc
//
LOCUS       DAJSMK010000030        24741 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.030, whole genome shotgun sequence.
ACCESSION   DAJSMK010000030 DAJSMK010000000
VERSION     DAJSMK010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24741
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.030"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ON488_001283"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="ON488_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HCR3231485.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
     gene            460..1041
                     /locus_tag="ON488_001284"
                     /pseudo
     CDS             460..1041
                     /locus_tag="ON488_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
     gene            1045..1686
                     /locus_tag="ON488_001285"
     CDS             1045..1686
                     /locus_tag="ON488_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231486.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1683..2600
                     /locus_tag="ON488_001286"
     CDS             1683..2600
                     /locus_tag="ON488_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3231487.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2597..3268
                     /locus_tag="ON488_001287"
     CDS             2597..3268
                     /locus_tag="ON488_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231488.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3809..4297)
                     /locus_tag="ON488_001288"
     CDS             complement(3809..4297)
                     /locus_tag="ON488_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HCR3231489.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4498..4764)
                     /locus_tag="ON488_001289"
     CDS             complement(4498..4764)
                     /locus_tag="ON488_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCR3231490.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4764..5027)
                     /locus_tag="ON488_001290"
     CDS             complement(4764..5027)
                     /locus_tag="ON488_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCR3231491.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            5503..5688
                     /locus_tag="ON488_001291"
     CDS             5503..5688
                     /locus_tag="ON488_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR3231492.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5830..7653)
                     /locus_tag="ON488_001292"
     CDS             complement(5830..7653)
                     /locus_tag="ON488_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HCR3231493.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(8251..10956)
                     /locus_tag="ON488_001293"
     CDS             complement(8251..10956)
                     /locus_tag="ON488_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HCR3231494.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(11262..12209)
                     /locus_tag="ON488_001294"
     CDS             complement(11262..12209)
                     /locus_tag="ON488_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HCR3231495.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            12399..12668
                     /gene="rpsN"
                     /locus_tag="ON488_001295"
     CDS             12399..12668
                     /gene="rpsN"
                     /locus_tag="ON488_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCR3231496.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12844..13206)
                     /locus_tag="ON488_001296"
     CDS             complement(12844..13206)
                     /locus_tag="ON488_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCR3231497.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(13217..14338)
                     /locus_tag="ON488_001297"
     CDS             complement(13217..14338)
                     /locus_tag="ON488_001297"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HCR3231498.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(14354..14704)
                     /locus_tag="ON488_001298"
     CDS             complement(14354..14704)
                     /locus_tag="ON488_001298"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HCR3231499.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14834..16345)
                     /locus_tag="ON488_001299"
     CDS             complement(14834..16345)
                     /locus_tag="ON488_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HCR3231500.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16667..18019)
                     /locus_tag="ON488_001300"
     CDS             complement(16667..18019)
                     /locus_tag="ON488_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HCR3231501.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(18172..19248)
                     /locus_tag="ON488_001301"
     CDS             complement(18172..19248)
                     /locus_tag="ON488_001301"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HCR3231502.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            19444..21189
                     /locus_tag="ON488_001302"
     CDS             19444..21189
                     /locus_tag="ON488_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HCR3231503.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21469..21906)
                     /locus_tag="ON488_001303"
     CDS             complement(21469..21906)
                     /locus_tag="ON488_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HCR3231504.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21890..23263)
                     /locus_tag="ON488_001304"
     CDS             complement(21890..23263)
                     /locus_tag="ON488_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231505.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23585..24073)
                     /locus_tag="ON488_001305"
     CDS             complement(23585..24073)
                     /locus_tag="ON488_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3231506.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(24095..24697)
                     /locus_tag="ON488_001306"
     CDS             complement(24095..24697)
                     /locus_tag="ON488_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCR3231507.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7105 a         5247 c         4567 g         7822 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgttatatc aactcatttc ttgtatagac tgattgtaac atggaacaaa ataaaaaggc
      361 aatacgcctt agttgtcggt cttcgagtta ccaacggtaa ccctcatacc gaacggcatt
      421 catcacccac ctatagagga tgggcgactt ctgcctaatt ctgttaaact agcaagccgt
      481 atcgccatca tgagtgaagg ccgtgtgatc caatttgata caccagaaaa tattttacgt
      541 catcctgcaa acgatttcgt agaagagttg attggagaag atcgcctact acaagccaag
      601 ccaaatgcga caagagtcgg cgaagttatg ctaaatacag caatcacgat tacaccggaa
      661 aaatcattac aagaagcaat caaactgatg agggaaaaac gtgtagatac gttgttagtt
      721 accgataatt cgaatgtatt aaaaggattt atcgatgtag aaacgttgaa taaaaaacga
      781 ggaaaagtat ccagtgtcgg cgacattttg aataaacatg ttttttacgt aaaagaatcc
      841 gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc
      901 gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg catcattagt ggatatcgtc
      961 tacgatgtga tttggggaga agatcccgca actactgatg ttgcagagtc agctactcct
     1021 gaagaatcta aggaggtctg acctatgcag cagttttttc atcagcacgg ttcagaaatt
     1081 ctctcaaaag gttttgaaca tctttatatt tcaggacttg ctttgatcat tggtatcatc
     1141 attgctgtac cgcttggtgt cttactgaca cgttttccaa aagctgccac gattgtgatt
     1201 ggcttaacca gtgccttgca gacaatccct tctcttgctt tattggcatt gatgatcccg
     1261 ctatttggcg taggtaaatt acctgcgatt atcgcactct ttatttattc attattgccg
     1321 attttacgta atacgtacat tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca
     1381 aaaggcatgg ggatgactga gttccaatcc attttttccg ttgaattgcc cattgctatg
     1441 ccaacgatca tggctggtat tcgtttagct gccgtttacg tgattgcatg ggctacactt
     1501 gcctcttata tcggcgctgg tggtttaggc gatttgattt ttagtggact gaataattac
     1561 caaccagatc tcattttggc aggtacgatc cctgtaacaa ttttagcact attggctgat
     1621 tggcttctag gtctcttgga acaccggctg acaccgatcg cacttagaga ggagaatgaa
     1681 gaatgaaacg tatactaaaa atgaccatgg ttcttttctc tcttcttata cttgcgagtt
     1741 gttccttccc tggtcttgcc agcaatacag atgaagacac catttcgatc acaggtggaa
     1801 tcacttcaga agcacagatc ttagcaagtc tagttgccgg aatggttgaa cattatacag
     1861 ataaaaatac cgcaatcatc aacaatctgg ctactacaac tatcaaccat caagcgatga
     1921 tgaacggaga tgcttcaatt tcagcggctc gctacacagg aacagattta acgactacat
     1981 tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg
     2041 agaaaagata cggtcaaacg tggttcccgt cctatggttt tgaaaatacg tatgtctttc
     2101 ttgttcgaaa agacaccgca caaaaatacc atctatctaa agtcagcgat ctgaaaaatg
     2161 tagcggatga attagtagct ggtgtagata cttcttggat caatcgtaaa ggagacggtt
     2221 atgacggctt ccaagaaact tatggcttct ccttcaattc gatattacct atgcagattg
     2281 gacttgttta tgacgcagtc gaagcaggaa aaatggatat tgttcttggc tactctacgg
     2341 atggacggat cgccagttat gatctagtca tgttggaaga tgatcgtcaa ttcttcccac
     2401 catatgatgc tgctccagtt gtagacaaca agatattagc tgatacgcct catttaaaag
     2461 aagccttaaa taagttaggt cataccatca gtacggaaaa aatgcaggaa ttgaactacg
     2521 aagcagataa taatctagtg gaaccatcag tagtagcaca acgtttctta caagaaaacc
     2581 actattttga agggaagtga agcaattgga taaaatgaat gtctttcaac aatttttcta
     2641 ttatttccag gaaaatggct cctatatctt tgcacaattt atccgtcact tcctgatttc
     2701 tatctatggt gtcctctttg cagcagttgt cgggattccg gttgggatca tgatttctag
     2761 gagacgtaaa ttagcaaact gggtgattcg tttggcgaat atcatccaga cgatcccttc
     2821 tctagccatg atctccattt taatcattgg attaggcctg ggagtcaatg tcgtgattgt
     2881 tactgtattt ttgtattccc tcttaccgat catcaagaat acgtataccg ggatgatcca
     2941 agtagacaaa aacatccttg atgtcggcaa aggcatgggg atgactgcta gacaacgact
     3001 attcatggta gagttaccac tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt
     3061 agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga
     3121 tatcattatc cgaggaacca atgcaacaga gggcacatcg attattttag caggtgcatt
     3181 gccaactgca ttaatggcga tcatcacgga ctggctttta ggtattttgg aaagacggct
     3241 agatccagcc agccgtacat cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc
     3301 atttgttggt cgcaaaggct tttttagttc tgtcattttt aaggcaataa tccactctga
     3361 ttcttccctc cttatgggca aagagttgct tttcttagct atttatccat tccgtatact
     3421 ccaacttcat actgccaacg ggttcatatc tgcatccacc gactaagttt ttttcttatc
     3481 cgctaaggca ttttgccaat ccattttccc atcactcgtc atggaattca taccacatga
     3541 tctctaaata ctcgtctgct tgttctttga attgggcatc aattcttaca tcctttggcg
     3601 tggctttcat ttaagccttt tccatcagtc ctcgattgtt cgatgccttc agctgcatca
     3661 tcaaaactgg tgactgccgt atcggtaact tcgatcatct tttatacaat cgggaacttg
     3721 ccatcctcat ccttggctaa aaacatatct agccattcca gcttctcgcc atgggaggtt
     3781 tgcggttcct aaaaccggta cacgattctt atggactgca tccgtcgcaa ctagacttgg
     3841 cgatacgatg atccttcacc agaagagcac ccccgtaaac caattgatcg atatattgcc
     3901 aataagaaaa gacattggcg taaaagatat cgatccctcg tgatgcattg ccgttgatac
     3961 tgctattcat ggccgaaagc gccacgactt taacttcttc cgtttgagtg acattcatgt
     4021 tcggcaatgt cgctttggat acccgctctg ctaaaggaac gacactggta ttgtatttcg
     4081 tatctgtatc ttttccaaaa gaccatgcca acgaatcctc tgggaaccaa taagacgact
     4141 ccggttgatt gtccattgct tttttcaaca tacttttggc tgtttctcga taaacgacat
     4201 ttccaattgt cttcgcctca ctttggcgat aatcgatggt cgttgccact gccaacacta
     4261 acaacgatgc tccaatttta ctgattttcc ttgtcacact tcttcctcct tgttttacat
     4321 aaacccgtca acattccatt cctaaactca aacaatgacc cttcaaaggt ggagatatag
     4381 gaacaaatta aagaaatcat gcaataaatc caagaaggtt ggttttagaa caaaaaaaga
     4441 gtctcctttt tggggagact ctttgttaac tatctaaaaa ggttggctct tctcacttca
     4501 ctcataatgt gtccaggcag aataaatttc tacaacttta ttttcctcat caactttgta
     4561 aaccactcga tgctgtctat tcagcctgcg tgagtatctg ccttcatgtg taggtctcag
     4621 cttttcaaaa gactgcgtgg gcatatatgg atcttccttc aatgtctgaa tcacttcttc
     4681 aaattgtttc tttaaattcg tttgcttgat ttttcttaaa tccactttcg cagagttttt
     4741 gattgcgact gtatagttac tcatcaaaga gcttcccaat caatatcatc gatattcgta
     4801 aagctactgt cgtctttttc gcggtctcgt actttatcta aagtacctgt ttgctcaaga
     4861 aaaagggttt cttgaatcgc tctccagtct tccagcccaa tcaatacagc attgtttcca
     4921 ctacgatcac taataatctc gatttcagta tgattttcat ttacctcttt caataactga
     4981 taaaaatttt tacgagcagt gctaggattc atcgttgtat tagccattgt ctctcctcct
     5041 ttttctgata taattatagc gtacttgatt aagtacgtca aaaaaataca ataaagcact
     5101 taaattcagc aaacttttcc tcttttttac atagagaaaa agaccccttt ttagggagga
     5161 tctttgtcca cgctcacttc ttactccttt acgactagcg gtagccaaac gtaaagtaat
     5221 tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca
     5281 acaccaatac acgaaggttc ctcgttgcag tgtgacttga ttgatatctt gaataacctg
     5341 aggatacgca cgaaagattt gtaacggtta ttcaaaactg attttggccg tcaagtcttc
     5401 tactgcctca aaaatgattg cctctttcgt ctcctgtcat tcatgttcac tatcgatttg
     5461 atacttgctt agaccgttgg gtttgtgaat caccaattaa aaatggcact gagttatggt
     5521 aacaaaaaat ggtcacttga cgaggctgag attcctactt atgaagacac atggcactta
     5581 agagtcgagg taaaggaaga agctgaaaat ataggaggct gtacattatt tggcaaagga
     5641 ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt acagctaaat aggaagaata
     5701 ataacatttc atacgctgtt cccatcttta atggcttata gagggcacct ttagctgaga
     5761 ataagacaaa acagaccctc tagcttcaat taagagctag agggtctgtt tttgatttta
     5821 aaacttggtt tatttcttca aatggtagct ataggtgctg acaacgatat tttcacgcca
     5881 agacaatcgc aatcttaacc gcaaacttgt ttggttatgg agaatattct gccagcgtct
     5941 gtttggtaca aattgaggaa tcaacacagt agttgtatag ttttgtttcg ctgcattttt
     6001 acttacgata tctacataac ggataattgg attttcaatc gagcgataag aagagtggac
     6061 gattgaaaaa cggacatctg ggaaatgctt tttaaattct gcttcgattt ctttttcttt
     6121 ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc
     6181 gtaattcaac gcaccgatat ttacccgtgt cacattcccg actaatacaa gaacggtatt
     6241 cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga agctgttctg ctactttttt
     6301 ataatgatca tggatcttat aaaaaatgaa cataacgatt ggcataatga tgaagaaagg
     6361 ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg attgcatatg agatgaacgc
     6421 acccgtaata ttggcaatcg atttgcttaa ccatcttttt ccttcttttt tccatttgac
     6481 gaccatccct gtttgagata aagcaaatgg aatgaacacg ccgatagagt ataacggaat
     6541 caagcgttct gttgagccat ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt
     6601 gataatccca ttggaatagc ctagtcgatc cccacgatct tgatacatgt gaggcatgaa
     6661 tttatctttt gccagattgt atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc
     6721 aactgctaaa atcagcgctg tagcaaattg aaggacgtaa tacaaaatac catgtccaaa
     6781 gacagcttta ccaatttgag acaaaacagt gacttctttt tcaggaacga tcccatacca
     6841 atagttgata aatgtgatcc ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa
     6901 tgtagcagcg gcattttttg ctcttggctt cttaaagaat ggtacagcat tactaatcgc
     6961 ctccacccca gttaaagagg aagaaccaga agaaaatgct cgtaaaatca aagcgataga
     7021 aacacccggc acagccgctc ctggaagtgc agtagcttgc aatggcacag cacctgtcac
     7081 gatattatat aaaccaacaa cgatcagtaa cgagatcaca aggataaatg tgtacaccgg
     7141 aaataatagg aacgatgcag attccctcag cccacgaaga ttcagcatca tcagtagcaa
     7201 aacgattgtc acagaaatag cgacttgatg accgtagagt gctggcaccg ctgatgtgat
     7261 cgcttcagca cctgctgaga cagatactgc tactgtcaac atgtagtcga tcaataaaga
     7321 gccaccggaa atcaagccag cattctttcc aagattctca ctgctgacga catatgctcc
     7381 cccgccatga ggataagcat ggatgatttg acgatatgat agcgttaatg aaatcaataa
     7441 aataataaca aaagcggcaa tgggtagcga ataccagatg gctgcagcag acaaagcgac
     7501 taaaacgaca acgatttgtt ccgtaccata tgcaatagat gataacgcat cagacgacaa
     7561 taatgccaaa gcagcaaatc gggttaattt gtgctcatca ttttcagcag attttaaagg
     7621 cttacctact aacaaccttt ttaagtaatc caatttctaa actcctttac acacaatttt
     7681 acttcaagtt ttatagtcga aaatttatag taaacaagat gttatagtac gctcactgac
     7741 cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct
     7801 ttttcaaacg ctttaataca gcaaaaatct aacatttttt tatgggcttt ttctttgaat
     7861 tctataataa aaggatagaa cttgacttag aaaatcaagt tctatccttt ttgatatctt
     7921 aacttttgga agagagatgt aaggctgctt tctacccatc attcttacta ctcgaagcat
     7981 agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa
     8041 gctcaaccaa attaaaaaca taagaagctg tttttatttg gtcgttctta ttacttgatg
     8101 cagagcagct tttttacaac ctcttggtac acggtgttca atcagctgac cctcggtatt
     8161 agctcaaaaa aacggcaaaa tatgaggaac tatttttcca tttttttctc taatactcag
     8221 gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa atatggctct catgcgccgc
     8281 ttctttgaat ttcgtcattt tttcttcgat gaacggatag attgccgttc ctacgattcc
     8341 aaagacaaca aacaaaccga tcatgatcca gattgctttc gtagcatttg gccaataaat
     8401 tcctcctgca gattcccgta acaagtttac cgcatgagta aatggcaaga acggattgat
     8461 catttggaag aatttccctg agacttggat cggatagttc ccgcctccgc cagagatcga
     8521 cagtactaag atgataatag cgatcccttt accgacatta tcgaataatg cagccaagac
     8581 atagacgatc atcatgaacg ctaaggcgat caagacagca aatgacacgc tgtagaccgg
     8641 attttggaca tctactccta gtaagaaaat attccctaat gtaacgatca agctttgcgc
     8701 aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt
     8761 gtttcggtct ttctttccta aatagtattc tgtcgtagca acacttgaaa gaagaacagc
     8821 gccgacccac agacatagtg cagtataaaa cggggtgcta gctgaaccgt tatttgcgat
     8881 tggataaagc gcattggttt gtagctcaac aggttgtgta aagaagtcac tttcttttgt
     8941 tgcgtctagt ttcaataatt tgatgacttc gcctagatcg acttcttgtt cgccttttcg
     9001 gatcgcgtct gctgcttttt ggataccagc tttgatattt ggccagtcat tgttgatcaa
     9061 gtccgcagca gcgttcacag ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa
     9121 tgtaccggtg atttcatttt ttagtgctgg ccaatcattt tggataaaat cagcggccaa
     9181 tcctaatttt tgctgaatga tcggtaattc attgttgtat aggtctgccc cttcattgat
     9241 gccattgacg atggtatcca tatttccatt cagcattgta ttggcatcat ggatttcttg
     9301 tccaattgca ggcatttctt tttgatattt ttctaaaatt gccactgcat tcgttacagt
     9361 tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc
     9421 ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga gaagtgacag tggaactgat
     9481 ttgacctgta ttgataccag caatgatgcc attgatatta ttaacaacgg catcaatttg
     9541 atctagcaat tcatcaatag ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga
     9601 taggcggttt tgcagattgc ttagcaaggg ttttaattga tttagctgat caataattgg
     9661 ctgtaatttc gtatttccag cacttgtttg caatttagtc aggaactcga ccagtttatc
     9721 gattgcattt tgttgttgag atattccgtc aataaagccg ttcaatacat tgctgatgtt
     9781 tttcttttca tcatcagtca gcttaccatc ttcaatagct gttcttacag tatctattaa
     9841 cgaacctgtc gttgttgcca cttgtccaat tgacttcaat gtaacatcta cactgtttgt
     9901 gatgcttggt atcgcatctt tcagctgaga ggcacctgat tttgtttggt ttgctagatc
     9961 acttgcctga ttttctaaat ttttcacatc tggcaagata tcttgtactt gttggatgat
    10021 cgtcaagcct tgttttgctt catcgattcc ttggttcatt gtctcttgga tcgaagcaaa
    10081 atcgccgtcg atctctgcta gttgcttacc ggcattttgg atctctggga ttttttcttg
    10141 caaatcaagg atgatttttg cttgatcttt caactcaggc attttgtcat tcaatgcaac
    10201 gactttttca cccatctcat ctactttagg gatgtaatcc acgaattcat ttgctttatt
    10261 cagtttttcc ttgatttcag gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc
    10321 gtcgatcgtg tccaaatttt catctgttga taaaatcata tctttaactt tattgatact
    10381 tactaggttc gtatcgatgt cgtaacctat ctcattgaat actttcaata aagtcgaact
    10441 ggctgttttg ataaattcat ttgtgatttg cgattggatc gaacttgctc ctttatcggt
    10501 gattttcggt gcaatcgcat tgattttttc atttaccgta tattcgattt ttggtttctt
    10561 gatatcacca ctagtaaaac tcagcagatc ttctgagaaa tcctttggca agtaaatacc
    10621 tgcgtaatac tttccggaac ggactccgtc ttctaattgt tcttttgaat caacgaattg
    10681 ccatcctaat tgtttatttt tatgaagcga ttcgatgact tgctccccaa tggccacttc
    10741 tttaccttga aactctgctg gcttgtctgc actgtaaaca gcaattggca gctctccagt
    10801 atttccatat ggatcccata atgctttgat gttaaaccac gcatatagcg aagggatgat
    10861 catgatcgcg atgatcagaa gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag
    10921 caaatataat cgaagcgtat ttttgattga ctgcatagtt ctcccccttc ttcttttttc
    10981 agctgaatta ctttaccatg tatttcatac ttttttcaat cggctttttt caaaaaagtc
    11041 gaatttttgg acatatcacg gcaattgtct cattgtaatc tcttacatat tgagaaataa
    11101 ttaaggatta cagcctttac tttatcatga aataaaaggg aaagataatt ttatgccaaa
    11161 gtttttatct attatacgta tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac
    11221 aaaaatgttt cagctttttt cgttttttat tcctgtattt cttatttttc gaatgacagg
    11281 atgattttcc cagcaggagg atgtccttca actagctgat gtgcttggat gacatgctta
    11341 agtgaagcag acagattcat tgaaataaaa acatgaaagg ctcctttttg gtaggctttg
    11401 attatgccag caaaggcttc tgcatctaga tattcctttc ttggaacaaa cgattcataa
    11461 aagccttcct ttttttgccg caaatctaga tctgggaggt catttaatgc aacatacctg
    11521 ccgcctggtt tcatgatctg gatgccggtt tctcctttga tacttccttt cgtcgcatcg
    11581 attacaaggt ctgcctgatc agcaaattgc agacctggat ttgttttatc ataagcagca
    11641 aatgctgaag ctcctaattt ttttaccttt tcctcatttt tactggatgc actggttaag
    11701 attcggattc ccttttcatg gagaagctgg atcagacttg acccgaccgc acctgatgct
    11761 cctagtatca ttacagtatc tgtcggctgg atttccgtca aatggttgat tagattataa
    11821 gccgtaattc ctggcgtgac cattccggct gcttcttccc aactcatttt atctggaatt
    11881 tttgctactt ttgctgatgg caacacgact tcttctccgt aagtcccgcc gactgcatgg
    11941 acagctactc gatcacctac atgaacagtt gtgacatctg aaccaatctc tgtcacaata
    12001 ccagcgccat cattacctgg tacataaggg aatttcaatg ttcgtatctc tttcatttct
    12061 cctaaacgca aggcaacatc ataaggattc acactgaatg cttttatttc tacacgaaca
    12121 tgtccagaac cgacttctct gggatgagca tcgatttctt caaaaacatc ttgtgcttct
    12181 ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct ccctttttct ttaagtttac
    12241 gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca
    12301 aaatagttgt cttttttcgc gtaacgtgtt aaattattta tctaaaagcg taaagattac
    12361 gatttacgct aataaaaaat aattggagga atttgttgat ggctaaaaaa tcaaagattg
    12421 ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc tgctttacgc caggaattaa
    12481 aagcgcaaaa agattacgaa ggcttgcgta aacttccttt agatgctcgt ccagaacgat
    12541 tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt
    12601 cccgtataaa attccgtgaa ttagcacata aaggtttgat tccaggagta aaaaaagcca
    12661 gctggtaatc caagtctggc tgtaatgtaa aggaggaggg cgcatggacc actccttgga
    12721 tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc tggtactaga agcagacgta
    12781 tcttttttta cgcacagctg gtcctttttt atatgtaaag gctgcatggt tacttcgcta
    12841 tatttattta gtaacaggag tcagtgcttc gatacccaca ctaattttca atgctcggtc
    12901 aacttctgcc ataatgggtc gatccaaatg gcagaccttt tctttcaatc ttgatttatc
    12961 gatcgttctg atctgctcca acaggataac ggagtctctt tctattcctg ttccagtagc
    13021 tttgatccca atgtgagtcg gaagcttagg tttagccatt tttgccgtta tggccgcaac
    13081 aatgatcgtc gggctaaaat ggttacctag attattttga ataaccaaaa ctgggcgtgt
    13141 tccgccttgc tccgatccca cgactggaga aagatcagca aaataaatat ctcctctttt
    13201 taccatagga tcctccttat tcttgatatt ctcttggtat ccgctgtcct aatccgcaag
    13261 ccacttcata gtggatcgta cctaattgat ctgctatatc ctgcatagtg atttctttgt
    13321 ctgcattttt gccgataagc gtcacttttg ttccgacagg aaattcttga ggcaatcgga
    13381 tcatcagttg atccatacat acacgcccaa tcgtttcaca gtagttccct tctaccaata
    13441 gagaaaaacc ctgcatcttt cgtggccagc catctgcata accgatcggt atcgttccga
    13501 tccactctgc ttcaggagtg atatatgttt ctccatagcc gattccttca cctgctggga
    13561 gttttttgac ttgaatcaat tcagaaacca gctcaagtgc tggctgcaat ggataaactt
    13621 ccggtagtgc gtgcccagag ggattaagtc cgtacattgc tactccataa cgaatcatat
    13681 tgccgattgt ttcatcatgc cataaagccg ttgcactatt gctgacatgt acatatcgag
    13741 gaagttcggg aagttttttc agcacttcta taaagcgttc tttttgcaga ttccaatatg
    13801 tatcatctgc ctgatctgct gtagaaaaat gggtaaataa accttcccat tctaatacac
    13861 gactttcttt gatgaatgca gctgcctctt ttacttcttc aggtgtacaa aatccgatac
    13921 gacccatccc agtgtctgct tttagatgaa tcgaaagagg cgtctctagc ttacttttct
    13981 ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc tgcagttact gataaatcat
    14041 gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt caagataagg atgggctgag
    14101 taaatccagc ttctctcaac tcgactcctt catctaaatt tgaaacacaa aagcccgaag
    14161 ctccacctgc aactgctgcc tcagctgttt caatagctcc atgaccgtat ccgttcgctt
    14221 ttactactgc aaacaattct tttccttgcg gaagtcttgc aacttcattt gctacatttt
    14281 cagttatagc ttttttatgt atcactgctt tcgttgggcg gtgccaagcg acaaccatcg
    14341 tttttccttc tttctagtct tccaaaataa tttgtgcaaa agctgtttca tttgtatgag
    14401 taatactgac ccatacattg ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt
    14461 cattttttaa aatctcgaca tcttgaaagg taacttttcc gatcccagtt ccccaagctt
    14521 tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag
    14581 gcaaggactg gaatagtttc atttcatcag aggtcaagat tcgtgcaatg aattttggtt
    14641 tttcttcgat cagccgagtg atcctaggaa gttcgactgc atcgatccca attcctttta
    14701 tcatatgctt ttctcttttc aataaattta gaacactctc attctaccaa attataacca
    14761 ttttgccaca aataagtcca caaataacaa aaatgaaagt ttctcttaaa aaagagaaac
    14821 tttcatttta tgtttaatcg ttatttgaac ggattacaaa tccgcgtttt ttatcattgt
    14881 gacgtttacc gccatctttt tggctgttat tatttttgct ataaccgcct tttgatttgt
    14941 ttccacgata attaccgccg tcacgacgat tacggttgtt tccgccacca cgtttgccat
    15001 ttttattgta tccttttttc tgcattggca atgggcgttc tggtgtgatc ttcactggca
    15061 ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag
    15121 aatattcttc taataattta tctgctgttt gcaggtattt atctagacca ttttctgcaa
    15181 gttttgtttc gatttgttca actgcagcac ctaattgacc tttgaatgct tctttttcgg
    15241 ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt
    15301 ccatttcatt tggtgtaacg aaagtcacag acataccgcc ttttccggca cggcctgtac
    15361 gtccgatacg gtgaacgtag ctttctggat cttgagggat atcatagttg tacacatgag
    15421 tgacacctga aatatctaat ccacgtgcag caacgtctgt cgctacaagg atatctaaat
    15481 gaccgctctt aaatgaacgc aatacgctca ttcgtttttg ttgagacaaa tcgccatgga
    15541 ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc caattcgtct acacggcgtt
    15601 ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac atcaaacaag cgagtcatga
    15661 tatcgaattt ttcgtattct tttgcgcgga catagtattg atcgatcaag tcagctgtca
    15721 tttctttcgc tttgatcttc acatgatgtg gatttttcat gaatttaacg ccaatattct
    15781 tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg
    15841 aaatgatttt ttcgatatct tccaagaagc ccatattcaa catttcatct gcttcatcca
    15901 aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac
    15961 gtcctggtgt acccacaacg atatgtggac gatctttcaa gccacggatc tgacggccaa
    16021 tatctgctcc gccgtaaacg gcttgtacac gtactttttt gtcgcgccct aaacgatata
    16081 attcttcttg tgtttggata gctaattcac gtgttggtgc gataactaaa ccttgtaatt
    16141 cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc aaatgcagct gttttccctg
    16201 tacctgtctg tgcttgtcca ataacgtctt ttccagctaa tgctagtgga atcgtttctg
    16261 cttggatagg cgttgcttct tcaaaaccag cgcgttcgac tgatttcaac aattctggtg
    16321 ataattctag ttctttaaat ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt
    16381 agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt attgtttctt tttgacagtg
    16441 gccacgcacg tttttatcca ttcttagccc ctgtggcacc accgaaaaat cactttgcga
    16501 agtttaggca ttagaaaagc caaacgggtc gcgttcagct ttatcattat tatgacatct
    16561 ggcttcaaca agttgtttct atggcaaaac cagtccaatt tctcttcatc tttcggcaat
    16621 aggttattct aacatagttt ttcgttttct gcaagtttac agatttttat ttcatttgct
    16681 gaagttgttc taccacttca aataagccca tgctgttgct gccttttagc ataatactat
    16741 ctgttgctgc aagattttgt ttgatagcat caatcaattt attcttttct ttttcaaaat
    16801 agaacacagg tagttggggg tatttttggt tcaattcttc ttttagtgca tgcatttgtt
    16861 ccccataaag gaaaatcatg gcgaatttct caggatcgat atgttcactc atttgcgcat
    16921 gcatatttaa agactctttc cctaattcca gcatatctgc taacacagcg attctgcgtc
    16981 cttttgttgg cagattttta aaagtatcta ataccagtcc catggctgtt ggatttgcat
    17041 tgtagacatc gctcaaaata gctgcaccat ttcctgccgt tagccattcg gttctgtttt
    17101 gagtgataga aacatgggcg agcccttggc gtatctcagg tatggacagt ccaaagaagc
    17161 gcccgatcgt atacgcaatc aaagcattcg ttacattata acttccaggc agcgggatcg
    17221 taaatgtttc tccttctact acaaaatcgg tttgtgcttt tccttttgct gtcacttccg
    17281 catgaacatc gccatttcca ataccgaatg ttgtgactgt ttgtactaat gttgccgtta
    17341 aaggtgtcag caacggttca tctgcgggca caacgagtaa tccgtctgat acaagtccgt
    17401 cagtgatttc cattttggct ttagcgattc cttctcgcga cccaagattt tctatgtgtg
    17461 cttcaccgat cattgtgatt gctgcagctt ttggttgagc cataagtgaa agttccgtga
    17521 tttcattggc gtgatccatg cccatttcca aaacgatctt ttctgtatct tggggcatgt
    17581 gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt tccttgcgtc ttatatgttt
    17641 tgtatttttc agacaagaca gacgcggtta gatctttcgt ggtggtttta ccattgcttc
    17701 ctgtaattgc aacgacttct gcgcctactt tttccaagta ataggttgcc aattgctgca
    17761 tggctttcaa aggatctgct acaggaataa ctggaaaatt ttttggagct tgttcaacag
    17821 gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc ttgctggata aattcatgtc
    17881 catctcgcgt accagcaaga ggaacgaata aacttccttc ggttatcttc cggctgtcaa
    17941 attcgacatt ggtaatcttt gtcagtgcag agcattcgct gcccacggct tgtgcaattt
    18001 cttgtattgt tagattcatt gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc
    18061 ctaaacggcg ggttcgcatg actctcactt ccaagtaaat ttctctattc gtatttagaa
    18121 gctagaatga acgcggttac gcaatcactc cagcctcttc tttatttctc tttattcatt
    18181 tttttcaaaa aaagattgac gctgatggta tcgattcatt cctaactgga tcagttcttc
    18241 aatcaaatca ccgtatttca agcccatatt ttcccataag agtgggtaca tactgaactc
    18301 cgtaaatcct ggcatagagt ttaattcatt caggaataat tcatttttat ttgtcaaaaa
    18361 gaaatcgcac cggctcaatc cgcttccacc taacatcgtg taagctaact tcgcgtactc
    18421 ttgcgctttt tgataaactt cttctggcac ttcggctgga atctgcattt cgattttatt
    18481 attgatatat tttgcttcat aatcatagaa tgctacgtct tttacgactt caccaggcaa
    18541 agtcgtccga acgtcttcat ttcctaatac agcaacttcg atttcgcgcg cttcaattcc
    18601 ttgttcaacg attgctcgag aatcatactg ataggctgtt gctaaagcat tttgcagctc
    18661 ttctcggttt tctgcttttg taatgccgac actagaaccc atattcgccg gtttgacaaa
    18721 catcggataa agcaaagaac cttcacattg atcaaatact tttttaggat tttctttcca
    18781 ttgattctta agtactggta cataaggaac ttgcggcaca ccagcagctt gtaaaatata
    18841 cttggtcatg attttatcca tggcacatgc actggtcaat acgcctgcgc cgacataagg
    18901 catattcaat gtctctaaga agccttggat cgttccatct tccccgtttg gcccatgtaa
    18961 aactggaaaa acgatggctc cttcttcttt gatttcgccc ggattgatca cttttcctgt
    19021 aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga tgcaagacat ctttgctggc
    19081 aggtttttct gttagtaatg gacctttgac ccattgtcct tcttttgtaa taaatacgag
    19141 ttgaacttgg taataattat aataaatggc atttaaaact gaaaatgcgg aaagaatgga
    19201 cacttcatgc tctgcgctgc gtccgccata tagtaaagta atcttcaaaa gattgtcctc
    19261 ctgtattcta aatcgttcag tgatttactc tcatatttta gcacaaaaca aaaataaacg
    19321 aataacttat ttataaaaaa acgagccagc ttctaaaaga acgagcgtca tttatttttt
    19381 gtcagctaga ttatttgtcc cgttttttat aaaaagttat gataaagaaa aggagggatg
    19441 atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa tcattcgagt gttcatcaat
    19501 tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt
    19561 gaagaactag gccccacctt catcaagata ggacagatgc tttctgttcg agaagatttg
    19621 ctttcttctg ccttcactca aacattcaaa acattacaag atagtgtacc tagcgacaca
    19681 ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc tttcattatc agatatattc
    19741 gatgattttt caaaatcgcc ttttgcctct gcttctatgg ggcaggctca tcgtgccaag
    19801 ctgaagaacg gtgacgcggt agtcgttaag atccaacacc ctaacatcgc cgaagagatc
    19861 cgacttgatc ttcaactatt tgaacgagcg atccctttga tcaaatacat tcctgaaact
    19921 agcgtagttg atctaaaagg ggtactccaa gaagtaaaac gttccttgat caatgaaatg
    19981 gacttcttaa aagaaagtca aaatggcgaa caattctatc aaaagaacaa tggctggaaa
    20041 gagatccgca gccccaagat ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa
    20101 gaaatgtctg gtaaaaactt gaatcattta atgaacgccg aaaacaaaac tgaaactttt
    20161 atcactggaa ttcaaaacaa gcagctgaaa caagaagttg caaagctttt agttgagaac
    20221 tttatgaaac aggtgtttga tgatggtttt ttccatgctg atcctcatcc agggaatctg
    20281 ctattccatg tactaacaaa agaagaacag acacaagcta gccgaaaaac tgaaacagtc
    20341 catgaaaaag agttcggttc ctttgctttt cgagcctcca cttctgcaga agaccctgtt
    20401 gcgccatata ccatcaacta catcgatttt ggtatgatgg ggcatctttc tgcaggactt
    20461 aggcaaaaac tcacacaagc cgttttagcg ctgtatacga aagatgctta tcgaatcgaa
    20521 aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa
    20581 gaactgacaa gttttcttga acagtattat gattctccta ttgatgaaat caacttgcaa
    20641 gaagtattca cacatgtcgt gacgatttgt catcaaaata atctgcagtt cgatcgtgat
    20701 atcacgcttt tgctgaaagc atttgggaca ttagaagggg tgatccgcgt cctcgatcct
    20761 gaagtttccc tcatggaagt cgcttcgcct tttgctcaac attattttct cactcatctg
    20821 gatgtagaag atacattgaa acaaagcgga ttagacttat tggaagggat gaaggctgcg
    20881 cctaagatcc ctcaacagct ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa
    20941 gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca ggatcgaaag tatgatcaat
    21001 cggcttgttt tcggtatgat tttagctgca ttgatcgtag ggtcctccct gcttgtccaa
    21061 gcagcacctg tagaaaacgc agaggtcgtt tccttattag ggatatttac gtatgctatt
    21121 gccgcattcg tcattatttt tttggcaatc gatgcattga tccaaatgta taagaagagg
    21181 aaaaagtaga aaaaggttgt gacagaaaga atcagcttca agaaataaga aggggtttta
    21241 cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct
    21301 gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca cccagtaata agaacaatca
    21361 aaaagggaac atggaacaca tttatcctgt ttccctgttc cctttttgat gtattcgagc
    21421 ataaataaaa taccttcgtt acctactatc ttctgtactt ggtaaacctt agtcaattgc
    21481 cttttttaac gcttgacgaa aagacatatg atctttctcc gtaaagggtt ttggaccctt
    21541 tgtccttatg ccagcttttc ttaactttcc actatgataa cgttgttcta gaagcgtgcc
    21601 gatattcgct tcgtcaaatt cttttccaga gtgatggaac actcgcacac ccttcggcaa
    21661 tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag tcattcttct taaccatacc
    21721 gacgatttta taatccgcac tatcagctcc gcggtctacg tagacgattt ggacatgatt
    21781 agcgtattct ttggtcgtat aatggtccac actggtcacg ataaccacgt caagaccata
    21841 ggattctcct aattttatga catcttcttt tactggagaa ccatctccat caatgaatag
    21901 cctcattctt tttcgccttc ttccataaat gataaacagt tactaatccg ctcagtaaaa
    21961 gaccaacatt gatccatttt gccaagataa gcagttgtac actttctatc ggcactgatt
    22021 catggttcag cgtgatcaat aatagatgga ttggctctcc catttctttt gctaaaacaa
    22081 acaaaagcgt catcaataaa aactggtgga tcacactccc tttattttga gtagtatact
    22141 tgacaacgat ccggcgatcc attggaatag ctgtatcagt ttgataatat tccttattta
    22201 gccagctgcc tgttactacg tgccagaaac taagcagaaa gacacctatc gcaaaaccat
    22261 ttggaatcaa gaggaccaat aaagaagaac tcagtccaag caattgcata gccaatggag
    22321 accatgttaa acgtttcaaa atccatggtc cgactatttt tgctgcaatc aagcctgctg
    22381 cataaggcaa atacataaaa atcgaaagtt tttctaatcc gtacagtatg ccaacataaa
    22441 aactgctaaa taaaaaaagg aaattcccta gcattccatt tagaaaagta aacagattta
    22501 gccagcttgg caacttccat tccttcttct ggtgtcctaa aacaaacacg aacaagatga
    22561 acagcagcaa gaaaccataa atagcaagat caaaaagcct ttcatcgaat aacaatcggg
    22621 catttctcaa aagaaacaat aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag
    22681 ctaccagatt tcttttgatg tctttgaaat ccagttcgta acgcggataa tgactaaccg
    22741 tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg
    22801 gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca gatagctgca aataagtact
    22861 ttttcccatc catattgata aaaccttgcg tcttttcgtg aaaattgacc gtggtattag
    22921 caggtacaag ccatgctgca ctcagcccta gcaaaacact tgaaaaataa aataaaggaa
    22981 aataaaatac gcctaatatt ccaagcaatg aaccagcacc accaatcagc agagcgatca
    23041 tcagcaacgt gtaactatct agaccaaatc gtagactgtt gactaaaaat agtccagtca
    23101 tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag ccaattatgc gagtctgtta
    23161 gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt acttaagata aagggcgttg
    23221 tttgtgtaaa attacgccca aatcgtttga gtttttcgaa catgacaatg gctccttaaa
    23281 cagtcttata actaatctgc tcttcgattt tagcattaaa ggggaaataa accaatttta
    23341 cagaatatat tcttgtaaaa aaaaatacag aaagaagcat aagcttcttt ctgcattttt
    23401 acggtacttg attactcaag cagacaagcc cttctccaca aaagtcttgc ccgacacccc
    23461 tgcatccggc aggtgataaa gatagaaatc aattatcctg tgcctccaaa atcaattagg
    23521 agctctgtaa accagagtcc ttctcgaccc gtcgcataaa tttactttaa cacagttcct
    23581 atgtttatgc gagagctttt ttcattttat aatcgaccat ttgaaatcct tgaccgatat
    23641 ctgaaataag ttcttctgta atctcaaatc cttcatgctt ataaacctcg attgcttgat
    23701 gattcccctg attcactcgc aaaaagatct ctctttcctt tgtttgcgca gcaagttctt
    23761 cataccagcg aaaaactgaa gaagtcaatc cttgaccacg tactttattt agcaaatata
    23821 atttacttaa ataaattttt ccatttatct cttcataagc agtgtaaccg acagtctttt
    23881 cttcgctttt taataaaaag taggacacac cttctgtcag ttctttttga atctgttttt
    23941 ttgactgata agttttcagc atgtaatcca cttgtttttg accaatgatc ggcacaaaag
    24001 cttccggcca tacttcttgt atgactgcca tcagctcatc cagttcattt tctgttactt
    24061 ttattttttc catacaccca cgtccttttt tacattataa atgaccttgc gcttgatgga
    24121 ataaaaagag catgatcatg ctatacacac ccaccgacca tggtttcaag aaaatcacaa
    24181 tctgcataaa ttccctaaaa gataatttcg tcaaaccagc tactagacag atcaagtcgt
    24241 ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt tttaatatct ttcgtttttc
    24301 ttgtcagcaa ttcatcaaat ttctgatact tttttggcga taaaataagc tggacaaagg
    24361 ctacgccata gtaacggaca agcaaaaatc cgattgcttc cccaatcact aggccaatac
    24421 aactatataa aagcccaaat ccattgccaa acatcagcat gcccgctact gaggagatcc
    24481 ctcccggcaa aataggaatg atcacttgga tcacttgcaa cagaacaaat atcatcactg
    24541 catacttgcc aaattgctgg ataaacgctt gcaaagacgt gctcgatcga aaaatcccat
    24601 gatgataagc ataaagaatc aacacaaaga aaaaaaacag accaataatg ggcatgatct
    24661 gaagacattt ttgtaaaact gatccttttt tagacatcta tattccccac atcttttttc
    24721 atttattaaa actgcctcct t
//
LOCUS       DAJSMK010000031        24505 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.031, whole genome shotgun sequence.
ACCESSION   DAJSMK010000031 DAJSMK010000000
VERSION     DAJSMK010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.031"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(270..638)
                     /locus_tag="ON488_001307"
     CDS             complement(270..638)
                     /locus_tag="ON488_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HCR3231508.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            788..1270
                     /locus_tag="ON488_001308"
     CDS             788..1270
                     /locus_tag="ON488_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HCR3231509.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            1307..2317
                     /locus_tag="ON488_001309"
     CDS             1307..2317
                     /locus_tag="ON488_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HCR3231510.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(2432..3145)
                     /locus_tag="ON488_001310"
     CDS             complement(2432..3145)
                     /locus_tag="ON488_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231511.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(3335..3925)
                     /locus_tag="ON488_001311"
     CDS             complement(3335..3925)
                     /locus_tag="ON488_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HCR3231512.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            4409..4636
                     /locus_tag="ON488_001312"
     CDS             4409..4636
                     /locus_tag="ON488_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HCR3231513.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            4652..5818
                     /locus_tag="ON488_001313"
     CDS             4652..5818
                     /locus_tag="ON488_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HCR3231514.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6052..7095
                     /gene="hrcA"
                     /locus_tag="ON488_001314"
     CDS             6052..7095
                     /gene="hrcA"
                     /locus_tag="ON488_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HCR3231515.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7189..7752
                     /gene="grpE"
                     /locus_tag="ON488_001315"
     CDS             7189..7752
                     /gene="grpE"
                     /locus_tag="ON488_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HCR3231516.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            7803..9632
                     /gene="dnaK"
                     /locus_tag="ON488_001316"
     CDS             7803..9632
                     /gene="dnaK"
                     /locus_tag="ON488_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HCR3231517.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            9783..10949
                     /gene="dnaJ"
                     /locus_tag="ON488_001317"
     CDS             9783..10949
                     /gene="dnaJ"
                     /locus_tag="ON488_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HCR3231518.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(11031..11696)
                     /locus_tag="ON488_001318"
     CDS             complement(11031..11696)
                     /locus_tag="ON488_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231519.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            11672..11845
                     /locus_tag="ON488_001319"
     CDS             11672..11845
                     /locus_tag="ON488_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231520.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(11890..12627)
                     /locus_tag="ON488_001320"
     CDS             complement(11890..12627)
                     /locus_tag="ON488_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCR3231521.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(12629..14131)
                     /locus_tag="ON488_001321"
     CDS             complement(12629..14131)
                     /locus_tag="ON488_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HCR3231522.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            14390..16384
                     /gene="uvrB"
                     /locus_tag="ON488_001322"
     CDS             14390..16384
                     /gene="uvrB"
                     /locus_tag="ON488_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HCR3231523.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            16394..19210
                     /gene="uvrA"
                     /locus_tag="ON488_001323"
     CDS             16394..19210
                     /gene="uvrA"
                     /locus_tag="ON488_001323"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HCR3231524.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            19473..20738
                     /locus_tag="ON488_001324"
     CDS             19473..20738
                     /locus_tag="ON488_001324"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HCR3231525.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            20742..21473
                     /locus_tag="ON488_001325"
     CDS             20742..21473
                     /locus_tag="ON488_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HCR3231526.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            21608..22492
                     /gene="rapZ"
                     /locus_tag="ON488_001326"
     CDS             21608..22492
                     /gene="rapZ"
                     /locus_tag="ON488_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HCR3231527.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            22489..23487
                     /locus_tag="ON488_001327"
     CDS             22489..23487
                     /locus_tag="ON488_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HCR3231528.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            23521..24456
                     /gene="whiA"
                     /locus_tag="ON488_001328"
     CDS             23521..24456
                     /gene="whiA"
                     /locus_tag="ON488_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HCR3231529.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
BASE COUNT         8104 a         4225 c         5231 g         6945 t
ORIGIN      
        1 tatgaaagat cactgatatt ttctcgtatt ttttccttat tcaaaagttt tgcaggaaaa
       61 ttgctgaaaa aataatttta ctaagtagaa aattcaaagc cattcaatca gtgatttttt
      121 tcagcacaag aaagactcct tataaaaata gcagatactt tgtcaattaa gtgtttaacc
      181 agggatgata aaaaggatag gattgaacaa aacctgtata aggtgatgaa tagtttcctc
      241 gccagtaaaa ggtttattcg tataaagctt tatcgccaaa atttatcatg acctttttta
      301 tcttcaatat taaatgaaat caattgttca atcaattccc agttgattac acttttccaa
      361 ggaactttga tgacgttatc cgtatatacg tagcctgctt cttggatatt tttttcaagg
      421 gcacgaatcg ctgctttttc cggtgcgata gaaaaatgat ttttagcaaa actaaatgca
      481 ataataaagg taccatggtc agtaaacata ggttggttcc attttacagt tgtgtctagc
      541 tggggatacg tttctgttat cttagcaaaa aggtctttga tcttttgttg atgttctttt
      601 tctttgattt gattgatgat cggctgaaat ttttccattc taaaacgcct ccattaagtg
      661 gtttgattta ttttaccaga aaaacaatag ttatgtataa aaaacgaaca aaacacaagt
      721 aatgttgtaa ccgctatatt tatatgataa gatgtctcaa ataataaaat agaaaagaga
      781 cataaaaatg attgacttgg caaagaaatt cttacacgaa aatatatatt ttgagttgta
      841 tcatcatcga gccatttata caaatgaaga tgctttggta ataaagaaag aacaaggatt
      901 tacaggtaca gagaccaaaa gcttattctt aaaagataaa aaagataata actacgtata
      961 tctgactttt actacgaaac aaacggattt caaagcatta gggaagatcg tcggtaaaag
     1021 gctttctatt gtttcatcag aacgcatgga agaacaaacg ggacaaaagc agggcgctgt
     1081 ttctccgttt ggttatgaaa aacagattcc gattattatt gatgaagagc tcttatcaaa
     1141 tgaaaaactt gtttttgcac caggtagacc agatcaaacg atggtcatcc aaacggttga
     1201 cttaaacaaa atcatccagc tacttgagat gccgatattt ttgatgccgg caaacgaaaa
     1261 aaacaattaa ccaagtaaaa tagtgcatac ttggaggtga agcaacatga taagttatcc
     1321 attattagaa agaaatgcaa cgattggggt tactgcacca tcctcaggcg tatcagagga
     1381 acaccattcg ttactcgaat cagctttaaa gagaatggaa gaaaaatctt tccaagtagt
     1441 tactggaaag acgctttgga cgcaagataa ggaaaaatca ggtccagcaa gaaaacgagc
     1501 agatgaattc aatcaaatga tgcaagatga aaatatccaa atgatctttc cgacttgggg
     1561 aggagaatta ttgattgaga ttctcgattt tgtcgatttt gatgctctac aaccaaaatg
     1621 gatagtaggt tattcagata ttagtacgtt gctacttgct gtcacattaa aaacagggat
     1681 agccactgca catggaacta accttattga tttaagagga gagtacttgg atgaaacgac
     1741 agcaatgtgg gaaagtgtac tgaaaacaag agaaggagaa tcgattctac agcaatcttc
     1801 tgaaaagtat caaaaagtgt ggccccatga gcattcatca tcttctgttt tccatctcac
     1861 tgaaccaaca aattggcaat cagtcagcgg agatgcagta aggatgaagg gacgattatt
     1921 aggtggttgt attgatacga tcaggcattt aatcggtact ccttatggag atgtccaatc
     1981 ttttaaaaga aagtataatg atggaaagcc gatcttgtgg tttctagaaa actgtgagct
     2041 atcgtcagtt gatttaagaa gatcacttgt tcagatgaaa ctggcaggct ggtttgatgg
     2101 cagctcgggg atcatgttcg gtagaagtgc ggcagaggat ttgttagatt ataaaatgaa
     2161 ggatgtatac gaagatctgt caaaggaatt aaaactaccg atcttgtatg atattgattg
     2221 tggtcatgta ccgccacaac tgacattgat taatggtgcc tatgcagaag tagcggtaga
     2281 agatagaaaa gcgactgttt tgcaaacgtt tatttaaaaa attttttcct gccttggagt
     2341 ctatcaaaga ccaataaatc taaatagaaa agaaagtgaa agaagctgac aaaatgctgt
     2401 cagcttcttt ttgtataaca tattagaaag tctaattatc tataactgtc acatcgatta
     2461 actgtttcac gtcattggga tttcctgtag gaatagctac tacagatgca ttatcaatga
     2521 tttcttgagt tgtttctcta atgaacgctg gataagatgt ttgatctgca ggcatttgcc
     2581 aatgtgaagg aactggataa ctagtgattg tcccgtcatg gttacttgaa tacactaaaa
     2641 ctccctggta actgtatttc ccagtgagca taaccacatc tttcggatag actgcactcc
     2701 ctgcatcata aggggcgata ggtgttcctg caggataatg aataacatgt aattcgaaat
     2761 cacccgatgt atctctaaaa gtattacctc taatagctag ccaaacacgt gcgtactcaa
     2821 tttgtagatc agaatatcct gctaacggat ctattgactg agaagactgt gaggaggttg
     2881 tgtctattgt tgaagaagaa atatttgtct caactgtact actagatgta gaagaagtat
     2941 tgggctctga gactttactg cttgttgaag atgtattcgt ttcagtagaa gctgatttct
     3001 gagtacttga tttttcagct gaactggttt gtctgattga acttttgtct gtggtcgcag
     3061 atggatcact attttcttta ctaggagacg tacatcctac aaggaataaa gagaccaaca
     3121 ataaaataaa acctaacttt ttcatataaa atacctcatt atttttttaa taccagtata
     3181 gcataatcct gaatttttga atccgtaaaa ccttgtctat gaatataaat agagtgtatc
     3241 ttctttgata aatgtcagaa aaagtgtgac aaataatcat cagtaaaatt acttgtcaca
     3301 ctattgataa ggagtattta attgaagaga atgattagga gaaaggatct ccgtactttt
     3361 tatagtaatc atagaatcca agtttgtata gacgaatcgt tttttctctt atttcttctg
     3421 tttcaaaatg gactgcttga agaatcaagt ctgtgaattc tataggagct gttccattcg
     3481 cagtaatcaa attacgatct ttcacagctt gttgttctat aaaatcttct ttattctgat
     3541 aattttccga ttctaaccaa ggaaattgcg catttccggt gtgtttgtaa ccttgcaata
     3601 atccgctctg agctaaataa tcaactgccc cacaaatagc agctactggt acgtctgttt
     3661 ttaacaattt atcgattatt tgatataaat gatgattttt tatgtcccat gaattgccac
     3721 cgatcataat aaaaaggtca actttttcag gtatttgttc gattaagtaa tcgatttttg
     3781 tttttaatcc tccaatggaa gtgacctctg attggataga agcagttttg ttttgccatt
     3841 tctcattttg gtttagtgtg ctagtaatat aagcaccttc ccaatcggca tattcctcta
     3901 atagaaacgt aatcgcagtt ttcattttca agctctcctt tactatctat aacaaggaca
     3961 acagttttaa cctacagaca ttcattaaaa ttgggtagcg acagcgaaaa caacaattct
     4021 taagttttag acagagtata cagatagtca acttaattaa atacgaacta aataaaaatg
     4081 acaggtaatc atttttgttt accagcatta taacattttg catacatgga tgacaaaaga
     4141 accaattccc acttgcttga gtacaatatt aaaagaaact ggaaggcaaa aagtaattat
     4201 agaaacgaaa aataaatcat atcgggcact cagacatgaa aacaacccta gagatatata
     4261 actaggtaac cagtttaatg aaagaaaaaa tcatccaaga agtcgattct tggatttttt
     4321 agtggatttg ttcgccaaat acgtttagta tgcgtatatg agaggttgta agcaaagcgt
     4381 tgtggtctga gcacttaagg aggaatctgt gaaaatagct tttcatattt ttgcagattt
     4441 tgacttaatg ccgaaggtca gctttgcgat taccgtttat cgagaggctg taaaagcacc
     4501 gtgtagctcc gatgacaata agcaagcatt tttagagcta ggtttccttg attctaaata
     4561 tgcggcttat ttcaatgagt tggtgcttga acgcgatttt aagaaggtcg aaaacaggca
     4621 cgacttttcg acgtaaggag aaagaatttc aatgatagaa acaataaatc ccgcagaaaa
     4681 caaggtttct gcgtacattc atatcccatt ttgcgagcat atctgctatt actgtgattt
     4741 taataaagtt tttttagaag ggcagccagt agatgagtat gtggaaatgc tgctgaatga
     4801 aatgaaaata atgctagaaa gtcatccgac agcgaattta gaaacacttt acgtaggggg
     4861 cgggacacca acttctttat ctgctaaaca acttgatcga ctgttatcag gtgctagaga
     4921 gatcctgcct tttcaaaatg gtaatgagtt tactgtagaa gcgaatccag gtgatttgac
     4981 ccgtgaaaaa cttcaagtaa tgaaaaacta tggcgtcaat cgtttatcca tgggagtgca
     5041 gacatttgat aatcgcttat tgaaaaaaat tggacgtaaa cacaccgcag aagatgtgta
     5101 tcaaactatg caatttttag aagcagaaaa ttttaccaat gtaagcatcg atttgattta
     5161 tgcattaccg ggacaaacac tagaaggata tctggatact ttggaaaaag ctttggcttt
     5221 ggatctgcct cactattctt tgtactcatt gatcctcgaa aacaaaacaa tgttcatgaa
     5281 ctgggtacga caaggaagac tcgaactgcc tgatcaggaa acggaaacca gaatgtttga
     5341 agagacgatt gaagcaatgg aaaagcatgg acgtcaccaa tatgaaataa gtaactttgg
     5401 gctctccgga catgaatctc aacataacct catgtactgg aacaatgacc actattttgg
     5461 gtttggagct ggtgctagcg gttatcttgg agatattcgt taccgcaaca aaggaccaat
     5521 ccaacactat ttacgcccat tacgagcaaa tgaacgcccg gtattggaag aagaaaaatt
     5581 gacacgaaaa aatcaaatag aagaagaaat gttcttagga ctaagaaaaa aaacagggat
     5641 tactaaaaaa catttctatg atcgctatca aaaaacaatt gaatcggtgt acggtgatgt
     5701 gctaagggaa ttagagcaag aagggttact tgttaatgaa gaagaccgtg tttatttgac
     5761 accaagaggg acctttttgg ggaacaatgt gtttgagcgc tttttgtttg aaaaatagtt
     5821 taaagaatat ttgtttttta tctgaattta aataaaaaaa gttcaaaaat acaataaagg
     5881 actattgaaa cgttgatata actggattta catcaattat ttagaattag cactcttgtg
     5941 tttagagtgc taaaaaatgg agtctttctc ttgacaggag aagggcttct tgctatattt
     6001 ataagtggat tagcacttag aatatatgag tgctaatgag aggtgaggaa gatgttaaca
     6061 aagcgacaaa acgacatttt acgtctgatc atccaacact atacgagtag tggcgtgccc
     6121 gttggttcca aaacattgat gtctgaggga gtcaaggcca gctcagcaac gattcgcaat
     6181 gatatgaaag cattagaaga tgaaggattg ctgttgaaga ctcactcttc ttctgggcgg
     6241 attccatctg ctttaggcta tcgttattac gtggatcatt tgttaaaacc tgctcgcgta
     6301 gcagaagatg atttgctgct gattcgtcag tctctaggca gagaatttca tgaaatcaat
     6361 gagattatta agcaatctgc tgagatatta tctgagctga caagctatac gactttttca
     6421 ttgggacctg aaataaaaga ccgccgactg actggctttc gtatcgtacc cttgaataat
     6481 cgacagatta ttgctatcgt cgtaacagat atggggaatg tagaaagcca agtgttcact
     6541 cttcccgaat atatgggaag tcaggaacta gaaaaaatgg tacagattgt aaacgaccgt
     6601 ctagtcggag atcctctgat gacggtgtac cataaacttc gtacggagat tccgatgatt
     6661 cttcataaat atttccaaac gacagaaggg atgtctcagt tatttgacac cgttcttggt
     6721 catgtttttg aagataaggt ttatgtcagt ggacaaatga atctcttgga ttatgagccc
     6781 cgtcaagatc ttgatcagtt caaatcgatg ttttctttta tgaaagactc agacggactt
     6841 acacaaatga tcactccgat ggatagcaat attcatatca agattggtgc tgaattaggc
     6901 aatgatttat tgcagaatat gagtatgatt caagcaagtt acgagataga tggtcatgga
     6961 agaggtacaa tagccttgtt agggcctact agtatgcctt attctcggat gttcggtcta
     7021 gtcgatgttt atcgaagaga actagcagct aaacttgctg attactaccg ttcgcttgac
     7081 ttgtcaaact cgtaatgtga ataacgaagc tatttgcagc tgatcgttct ctctttctta
     7141 gtaagagcaa tcaaacagct gactgaataa tgaaaggaag actgtatcgt gaaagaaaat
     7201 caagaagaac tagataaaga aatgacagat gctcagccag aaccggaaat cgatgtcgaa
     7261 gctgcagaag attcgggtat ttcagaagct gaagcggaag aattcgaaac agcgaaatta
     7321 aaagctgagt tagaagaaat ggaagataaa tacttgcggg ctcgtgctga aatcgcaaat
     7381 atggcaaatc gaggaaaaaa tgagcgtgag caattacaaa aataccgttc acaagattta
     7441 gccaaaaaat tacttccatc aattgacaac ctggaacgtg cattagccac agaagtgtca
     7501 gatgatcaag gggcaggttt gaaaaaaggc gtggaaatgg tcttggaaag tttgcgtaac
     7561 gcactggaag aagaaggaat tgaaaaaatc cctgctaaag gagaagcctt tgatcctaat
     7621 cttcatcaag cagtacaaac tgttccagcg actgaagata caccagccga tacgattgta
     7681 gaagtactac aagaaggcta caaattacat gatcgcgtgt taagaccaac catggtcatt
     7741 gttgcacaat aattgtgcgg atataaaact tacactttca attaaagaag gagacgttaa
     7801 ttatgagtaa aattatcggt attgacttag gtacgactaa ctctgcagta gcagtattgg
     7861 aaggaaacga agcaaaaatc atcgctaacc cagaaggaaa ccgtacaaca ccttctgttg
     7921 tatcattcaa aaatggagaa atccaagtag gggaagttgc aaaacgtcaa gctgtgacaa
     7981 acccaaatac gatttcatca atcaaacgcc atatcggtga agcaggttac aaagtagatg
     8041 tagaaggtaa atcatataca ccacaagaaa tctcagcaat gatccttcaa tatatcaaag
     8101 gattcgcaga agactattta ggtgaaaaag tcgaaaaagc agttatcact gtgccagctt
     8161 actttaatga tgcacaacgt caagcaacaa aagatgctgg taagatcgct ggtctagaag
     8221 tagaacgtat cgtcaatgaa ccaactgcag ctgctcttgc ctatggttta gataaaacag
     8281 atcgcgacga aaaaatctta gtattcgacc ttggtggcgg tacttttgac gtatctatcc
     8341 ttgaactagg agacggtgtc tttgatgtat tgtcaacagc tggcgacaac catctaggtg
     8401 gggacgactt tgataacaaa atcatcgact acatggtagc agaattcaaa aaagaaaaca
     8461 gcattgactt gtctcaagac aaaatggctt tacaacgctt gaaagacgct gctgaaaaag
     8521 cgaaaaaaga tttatctggc gtatcaagca cacaaatcag cttgccattt atcacagcag
     8581 gagaatctgg accattgcat ttggaaatga cattgacacg tgcaaaattt gatgaattaa
     8641 cagctgactt agtagaacgt acaaaagtac cagtacgtca agcgctaaaa gatgcaggtt
     8701 tatcacaatc agaaatcgac gaagttattt tagtcggtgg atctactcgt atccctgcag
     8761 ttgtagaagc agtacgtaaa gaaacaggaa aagaaccaaa caaatcagtt aaccctgatg
     8821 aagtagttgc tatgggtgct gctatccaag gtggcgtgat cactggtgat gtgaaagatg
     8881 ttgttttact tgacgttaca ccattgtcat taggtatcga aacaatgggt ggagtgttca
     8941 ctaaattgat tgaccgcaat acaacgattc caacaagtaa atcacaagta ttctcaactg
     9001 cggcagataa tcaaccagca gtagacatcc atgtattaca aggtgaacgc ccaatggctg
     9061 ctgacaacaa aactctagga agattccaat tgacagatat tccagcagct cctcgtggta
     9121 ttccacaaat cgaagtaaca ttcgatattg ataaaaacgg gattgtaaat gtatctgcga
     9181 aagatctagg tacacaaaaa gaacaaaaaa tcacgatcaa atcttcttca ggtctaacag
     9241 acgaagaaat cgaacgtatg gtaaaagatg cagaagcaaa tgcagaagca gataaagctc
     9301 gtaaagagga agttgaccta cgtaatgatg tagatgcatt gctattctct gtggacaaaa
     9361 cattgaaaga attagaaggc aaagtggacg aagaagaagt gaaaaaagca gaaacagctc
     9421 gcgatgaatt gaaagccgct gttgaagcaa acaacatcga agaaatgaaa actaaacgcg
     9481 atgcattgaa cgaaatcgtt caaaacttga ctgttaaact atacgaacaa gcggcacaac
     9541 aacaagctca agaaaaccca gaagcagctc aaggcggagc agatgatgtc gttgatgctg
     9601 attttgaaga agtcgatggc gacgataaat aatcagttca ctgaatttcg agagaaggcc
     9661 aaagttgcta ctttggcttt ttcttttgaa aaatagtttg aagtatcggt ttttgtttca
     9721 aacaaaatat gatatgataa caagcgacgt gaaaatgatg agaaccaata ggaggaaagc
     9781 ctatggcaac aaaacgtgat tattatgaag tcttagggct ctcaaaagga gcatcagaag
     9841 atgaaataaa gaaagcttat cgtaagcttt cgaaaaaata ccatcctgac atcaataaag
     9901 aacctgatgc ggaagaaaaa ttcaaagaag tatcagaagc atatgagatt ttaagtgacc
     9961 cgcaaaaacg cgctgcatat gaccaatacg ggcatgcagg cacagatcca aattacggtg
    10021 ctggtggagc tggtggcgga tttggtggat tcggcggctt ctctggtggc ggcttcggtg
    10081 gttttgaaga tatcttcgac tctttctttg gaggaggcgg tcggtcagtc gatccaaatg
    10141 cgcctcgtca aggtgctgat ttgcaatata cggtcgactt gtcttttgaa gaagcgattt
    10201 ttggtgtaga aaaagaaatc aagtataatc gggaagaaat ctgtcatact tgtggtggga
    10261 acggtgcaaa accaggcaca caaccaacta cttgtcataa atgtcatggt gcaggtacga
    10321 ttaatgtaga acgccaaaca ccacttggac gagtgatgag ccgtcaaact tgtgatgttt
    10381 gtcatgggac agggaaagaa atcaaagaac cttgtccaac ctgtcatggc tcaggacatg
    10441 agaagaaagc acattcagtt aaagtgaatg taccagctgg tgtagaagaa ggacaacaaa
    10501 tgcgtttagc tggtcaagga gaagctggag aaaacggcgg accatttggt gatttgtatg
    10561 tggtcttccg tgtagaagaa agtgatatct ttgatcgtga aggttctgaa atttactatg
    10621 aattgccttt aagttttgta caagcagctt tgggggatga agtccaagta ccaactgtcc
    10681 atggagatgt gaaattgaag atccctgctg gaacacagac aggtacgaac ttccgtttac
    10741 gtggaaaagg cgctccgaag ttacgtggtg gtgcaacagg cgaccaacat gtcaaagtaa
    10801 aactgatcac accgaaaaat ctaaatgaac aacaaagaga agcattacgt gcattcgctg
    10861 aagctggcgg catcaaagtt gaagaacagc aagaagacgg tttcttcgat aagtttaaag
    10921 atgcttttgg cgggaaaaag cggaagtagt ttttctagta aaaacgctaa gtcattaata
    10981 attaaaaacc agacgaacaa tcatatgttc gcctggtttt tttgtagttg tcatgtttgt
    11041 accaacaaaa aagccagctt tagaatatga taatcgtcat agtttctagg ggtataacca
    11101 gtgagagaat ggaacttgtt caatcgatat tgcaaggtgt ttttatgaat aaataattct
    11161 tctgagcaat ttttgatgct tccgttattt ttactgaagc atgccaaagt cttcttgaac
    11221 aaatgtactt cttcttctgt caggcttttc aaaatacgtt ttacatataa tgttcgttga
    11281 tctgacggga ttgctggtaa aacgatcccg aggtctaaat cttcaaaaaa gcggatctcg
    11341 ttcacagatt gatggaaagc tatccattcg caaacttgtt tggcatgaag gaaagattgc
    11401 ggtgtctctt gctctgtata acaaagcgac ccaattccaa agtttagctg taactgatac
    11461 attttattaa actttgtctg gattttatca agcaatgata gcaatgaggc tctggaaatc
    11521 cgattgacta ggataatgat ttgttgtcta tgtacagtga gcaaagcctg tccgtaataa
    11581 gagaagaccc tttcgagcaa ctccaataaa ggattgatcc gttcttgaca caattgctga
    11641 ttgtcagaaa gttgtcccac aactacataa tatggagaag aaaaatcaag ctcaattaag
    11701 tgagggtggt atcgactatg tacttgatat catcaatgaa ccgatggtac tttcttatgc
    11761 gatggaacag gtagagcgat tgcttgtttg tgcaggaaaa caagcgatgc ggctgatacg
    11821 attaggtgag aaaataagaa gataaaaata cacggtccct tcatggcgac cgtgcatttt
    11881 tggtttttat taaatattta atactttatt caagaaatct tttgtccgtt cattttgcgg
    11941 attttcaaag atttgttgag gcgttccatc ttctaaaaag tttccgtcgt caatgaacat
    12001 gacgcgattg gccacttctt tagcgaaccc catttcgtgc gtaacgataa ccatcgtcat
    12061 accttgttct gctaactttt tcatgacgtt caagacatca ccgaccattt caggatcgag
    12121 tgcagaagta ggctcatcaa aaagcatgat gtcagggttc atcgctagag cacgagcaat
    12181 agccacacgc tgtttttgtc caccagaaag catttcagga tacatatctt ttttatcttc
    12241 tagaccaact gtctgcagta atttgattgc ttttttctct gcttcttctc tagattcttt
    12301 cttcaggtcc atcggtgcta aaatgatgtt ttccaaaata gaaagatgag ggaataggtt
    12361 aaagtgttgg aataccattc cgatatgttg tctcaccaag ttgatatctg tgcttttatc
    12421 catcaagtgg gcgccgtcaa taataatttc accgtcagaa ggttcttcta aacgattcaa
    12481 gcaacgcaag aatgtacttt ttcctgaacc tgaagggcca atgatacaga cgacatctcc
    12541 ttcgttgatg gatacattga tgtcgtttaa tactgtgtta tcgccgtatt ttttgactaa
    12601 atgctcaact aagatttttt ctgccatctt acttcacctt cttttctaaa acttttgcta
    12661 attttgtcaa tgctgtgatc aaaatcaagt acatgatcgc aatgatcaag taaacatacg
    12721 tactttgtgt tgtacgtgca acaatgatct taccagtttg cagcaattcg actacaccga
    12781 ttgcggaaat gatcgttgtg tcttttaatg agataacgaa ctgattgacg aatgatggga
    12841 tcatgatgcg tatcgcttgc ggcaaaatga ttttttgcat tgtccgatta taagaaagac
    12901 ctaaacttct ggaagcttcc atttgtccga caggaacggc gttgatcccg cctcgaacaa
    12961 tctctgcgat ataagcactt gcgttaagag tcaaggtgat aacaccagca aggaagtcag
    13021 gaatcgtaaa tccaacgata ccaggcaacc caaagaaaat aaagaacgca agaaccatca
    13081 ttggaattcc tcggatgata tcgacataaa tactagcaat tgtgcgaaga gcgcgtattg
    13141 gtgctacact gaataatcca aaaatcacac cgattactat agccaaagca aaggagatca
    13201 aagttaggag aattgttctc caaagtcctt tcaacaatgc ttgatagttg ttttggataa
    13261 gtccaagaaa tgttgattca tcagcagtgg aagactcact ggaagtttct gaaccatccg
    13321 ctacatattc tttaataatc ttatcgtatt cgcctgttct ttttaattct ttcaatcctt
    13381 cattgaacat attaagaagc tcaggatttt gtcctttttt aacggcaaat gcatattttc
    13441 cgccagattc ttttttgatc ggtgtttcca attcttgtcc ttgtttgatc gcataaccga
    13501 ttaccggata atcatccatc attgcatcga ttgcgccaac ttttaacccg tcgtacaatt
    13561 gatcagcagc atcaaaatat ttgatagaat agccatattc agattcatgg tcgcttaaaa
    13621 attcagcact ttcggtacca acttttgctc cgactgtttt tcctttcaaa tcttcataag
    13681 acttgatcga agtatctcct tttttgacag ctaattggat cccgctatca aagtaagaat
    13741 cagaaaaatc atagcttttc tttcgttcat ctgttacagt cattccggca atcattccgt
    13801 ctgcttgtcc tgattccaaa gcttgcaaag cagcagagaa accacggtag tccattcgga
    13861 tgttaaatcc ttgcagtttg gcgatgtttt ccatcaattt tacatcgatg ccttcgtact
    13921 cgccctttgc gttttgaaat tcaaatggag caaaagcaga gtcactggca attacgtata
    13981 cgtctttttt gggctctatt ttttgcattg tctcgcttgt gcttgactct gccgttgtag
    14041 tgttgtcagc ttgtgcaaca tgaccaaacg caagtgtcac aagtcctgtc attaagaaaa
    14101 caaatgagtg aaataaatgc tttcttttca taatcaacct cctaaatttc caatatttta
    14161 ttattatagg cgaaaagtgc tgaatcagac aagactgtaa gctcgaaaaa atgaaaaaaa
    14221 tgcgagtttc taacatttta tgttataaaa cataacatgt ataataagat aaaaaagtgg
    14281 cgaaagtatg ttcggtgtgg tataattttt tagtaaggaa tgcctttgct ttccttttct
    14341 ttttattggt cgtaaaatga aaaggaatga atgaaaagga ggacgaagaa tgattgagag
    14401 agatacctcc cgacactttg agcttgtctc gaaataccaa ccggctggtg atcagcctga
    14461 agcgattaac caattagtgg atggcgtagt cggcgggaaa aaagcacaaa tcttattagg
    14521 tgcgactgga acagggaaaa catatacgat ttccaatctt attgagaaag tgaataaacc
    14581 aacactgatt attgcccata acaaaacatt ggctggtcag ctgtacgggg aattcaagga
    14641 atttttccct aacaatgctg ttgaatattt tgtttcttat tatgattatt atcagcctga
    14701 agcttatgtg ccttcaagcg atacgtatat cgaaaaagat tcaagtgtaa atgatgagat
    14761 cgacaaatta cgacattcgg ctactagttc attattagaa agaaatgatg tgatcgtcat
    14821 tgcatccgtt tcatgtattt ttggattagg ctcgcctttt gagtaccaaa aacaagtagt
    14881 ttcgattcga cagggagcag aactagatcg caatcagttg attcgtgact tagtcagtat
    14941 ccaattcgaa agaaatgata tagattttca gcgcggtcgt tttcgagtgc gcggtgatgt
    15001 cgtggagatt tttccggctt caagagatga acgtgcctta cgtgtggagt tttttggaga
    15061 tgaggtcgaa cgtatccgag aagtcaatgc actgacaggt gaagttttag gagaaacgga
    15121 acacgtagca atcttcccgg cgactcactt tgtgacgaat gatgaacata tggagcatgc
    15181 cgtagcgaat atcaaagcgg aattagaaca gcgtttaact gtcttgcgaa atgaaaacaa
    15241 acttctggaa gctcaacgtt tagaacagcg aaccaattac gatattgaaa tgatgttaga
    15301 aatgggctac acgtcgggaa ttgaaaatta ttctcggcat atggacggac gtaaagaagg
    15361 tgaaccgcct tatacgctat tggatttctt tcctgaagat tttttgatcg tggcggacga
    15421 atcgcacgta accatgcctc aaatcagagg aatgtataat ggtgaccgag cgagaaaaca
    15481 gatgctagta gattacggtt tccgtttgcc atctgcttta gacaatcggc cacttcggtt
    15541 agaagagttt gaaaaacatg tcaatcagat catttatgtc tctgcgacgc caggaccata
    15601 tgaacatgaa caaacagata ccgttatcca acaaatcatc cgtccgacag ggctgcttga
    15661 cccagtgatc gaagttcgtc caatcatggg acaaatcgat gatctagtag gcgaaataaa
    15721 tgaacgagtc gaaaaagacc agcgggtgtt tgtaacgaca ttgacgaaaa aaatggcaga
    15781 agacctcaca gattatttca aagaattagg gatcaaagtc aaatatttgc atagtgatat
    15841 caaaacgctg gaacgaacag aaatcattcg agatcttcga ttaggtgaat ttgatgtgtt
    15901 agttggaatc aatttgcttc gtgaaggatt agacgtacct gaagtttccc ttgttgctat
    15961 cttggatgcg gataaagaag gctttttacg tagtgaacgt tccttagtcc aaacgattgg
    16021 acgagctgct cggaatgaag aaggtaaagt aatcatgtac gcagacaaag taacagattc
    16081 tatgcgtcta gcgatggatg aaacgtcaag acgtcgtacg attcagcaga agtacaatga
    16141 agaacatggg atcgttccaa aaacgatcat taaagaaatc cgagatttga tttctattac
    16201 gaaagaatcg gaagatgata caaaagaagc ggtacaagtc tcgtacgaag aaatgacgaa
    16261 ggaagaaaaa gacacgttat tgatgaaatt agaaaaagaa atgaaagatg cggcaaaagc
    16321 tttggatttt gaaacagccg cgaatgtgcg agatatgatt ttagaattaa aagcttcaaa
    16381 gtaggaggac aacatggcta acgataaaat tacgattcat ggtgcacgtg cccataactt
    16441 gaaaaatata gatgtaacga ttccacgaga taaattcgtg gtcgttacag gtttgtccgg
    16501 ttctggaaaa agttccctag catttgatac gctgtacgct gaagggcagc ggagatacgt
    16561 agagagcctt tctgcttatg ctcgtcagtt tttaggacaa atggataagc cggacgtaga
    16621 tagcatcgac ggattgagtc cggcgatttc tattgatcag aaaacaacaa gtaaaaatcc
    16681 tcggtcgaca gtaggtactg tgacggaaat caatgactat ttacgcttgt tgtttgcacg
    16741 tgtaggacat ccgatttgtc ccaacgatca tatcgagatt accagtcaat cagtagatca
    16801 aatggcagat caagtaatgg ctttgcctga gcgcacaaag atccaagtgt tggcaccgat
    16861 cgtggtaaag aaaaaaggac aacataaaaa aatattcgaa cgaatccaaa aagagggata
    16921 cgtccgcgtt cgagtcgatg gtgagatcta tgatttaagt gaagtgcctg agctggagaa
    16981 aaacaaaaaa catgatatcg cgatcgtcat cgaccggatc attgtgaaag aagggattcg
    17041 ttctcgccta tttgattctt tagaggcggc cctgcgatta gcagacggct atgctctggt
    17101 tgacgtgatc ggtgaagaag aaatgttgtt tagcgaacac tatgcctgtc cttattgcgg
    17161 atttactgtt ggcgaactag aaccaagact gttctcattc aatgcgcctt ttggagcttg
    17221 tccagactgt gatggtttag gtgtcaaatt agaagtcgat caagatttag tgattccaga
    17281 tagaacgaag acacttagtc aaggtgctat cgttccatgg aatccaatca gctctcagta
    17341 ttatcctcaa atgttagcgc aggcttgtga aagtttcggt atcgatttag atacaccatt
    17401 cgaagaatta ccggaagagc atcaggagat catcttgaat gggacagatg atcttttcca
    17461 tttccattat gaaaatgatt ttggtggcgt tcgcgatgta gaaacgactt tcgaaggggt
    17521 attgaagaat atcgagcgtc gttatcatga tacgaacagt gatttcacgc gtgagcaaat
    17581 gcgtctttat atgacagaat taacttgtca gacatgtaaa ggttatcgat tgaatcccca
    17641 agctctatct gttcaaatca atggaacgaa tatcgggcaa acaaatgagt tgtctattca
    17701 aaaagcagta gatttcttct caaacttaac gttatctgaa caagagaaag taattgccaa
    17761 accgatttta aaagaagtaa atgacagact ttcattcttg gaaaatgtgg gactagacta
    17821 tctaactttg agtcgcgctt ccggaacatt atctggggga gaagcgcagc gaatcagatt
    17881 ggctacacaa attggatcga atctttctgg agttttgtat attttagatg aaccatcgat
    17941 cggattgcat caacgcgaca acgatcgact gattggctca ttaaagaaaa tgcgtgatct
    18001 tggcaacacc ctcgttgtag tcgaacatga tgaagatacg atgtgggcag cagattattt
    18061 gattgacgtc ggacctgggg ccggagaaca aggcggacaa atcgtggctg caggcactcc
    18121 tgaagaagta gctaatgatg aaaattcttt gacagggaaa tatctttcag ggaaaaaatc
    18181 aatccctgta ccaaaagaac gccgtaaagg taatgggaaa gcaatcaaga tcactggtgc
    18241 ttcagaaaac aatctgaaaa atattagtgt tgaatttcca ttaggagaat ttgtagcagt
    18301 cacaggtgtg tctggttctg gaaagagtac attggtcaat agtatcttaa agaaatcgtt
    18361 agcgcaaaaa ttaaataaga attctgctaa gccaggtaaa ttcaagacaa tttccggcta
    18421 cgaaagtatc gaaaagatca tcgatatcga tcaaagccca atcggccgga cgccgagaag
    18481 taatccagcg acttatacaa gtgtatttga tgatatccgt gggttatttg ctcaaacgaa
    18541 cgaggcaaaa atgcggggtt ataagaaagg gcgttttagt ttcaacgtaa aaggcggtcg
    18601 ttgtgaagct tgtcgcgggg atggaattat taagatcgaa atgcactttt tgcctgatgt
    18661 ctatgttcct tgtgaagtat gtcatggtaa acgatataat tctgaaacat tagaagtgca
    18721 ttacaaagga aaaagcattg ctgatatttt ggaaatgaca gtagaggatg ctgtagaatt
    18781 cttcaagcac attccaaaga ttcatcgcaa actgcaaacg attgttgatg ttggcttagg
    18841 ttatgtgacg atggggcaac cagcaacgac attgtccggt ggtgaggcac aacggatgaa
    18901 acttgccagt gaattgcaca aaatctctaa tggaaagaat ttctatatac tagatgaacc
    18961 aacgacagga cttcatagcg atgacatcgc ccgcttgttg catgtattac aaagattagt
    19021 agatgctggt aacacagttt tagtgattga acacaatcta gatgtaatca aaacagcaga
    19081 ttatatcatt gatttaggac cagaaggtgg agaaggtgga ggaacgatcc ttgcgactgg
    19141 aacaccagaa gaaatcatta acgtaaaaga aagttataca ggtcactatt tgaaaaaaat
    19201 aatggtataa agaggataga tagctgagat agttaaaaaa acataaaaaa atgaattttt
    19261 gcttgtttta ttaatatcag tgttctagaa tcattacatg gtagttcttt ctacactgat
    19321 tggtatagat aaaaacttcc tataagttca atccgttcaa aaaagaattg agcaatcgga
    19381 ggactttcct ttgattgctt ttttctttat ggtatgatat tccttgtgta gttggaaaag
    19441 aaaaacaaga gattatgagt aagtgagaga taatgatgaa cagtattgaa aatgaagaat
    19501 ttatccctat attattagga agcgacatga acgtttatgg tatggcacgt tcttttaatg
    19561 aagcatacgg caaaatctgc caagcatatg cttcggatca gttagcccct acccgctaca
    19621 gtaaaattgt caatgtagaa gttattccag gatttgataa agaccctgta tttatcgaga
    19681 cgatgcttcg tttggcaaaa gaaagatatt ctgataagag taaaaaatat cttttgattg
    19741 cttgtggtga tggatatgca gaattgatct cccaacataa acaagagctg tcagaatatt
    19801 ttatctgtcc atatattgat tattctttat ttgaaaggct gatcaataaa gtaagctttt
    19861 atgaagtttg tgaagaatat gatcttccgt atcctaaaac attgatcgtc agagaagaaa
    19921 tgttagtaaa tggacatttg gaacaggaat tgccttttga attcccagtt gctttgaaac
    19981 ctgcaaacag tgtggagtat ctttctgtcc aatttgaagg aagaaaaaaa gcttttattt
    20041 tagagactag agaagagttc gatttaattt taggccggat atacgaagcc ggttataaaa
    20101 gtgaaatgat tgtacaagat tttatcccgg gtgatgatag taatatgcgt gtgctaaatg
    20161 cgtatgtaga tgaagatcat caagttcgga tgatgtgcct tggtcatcca ctattagaag
    20221 atcctacacc agcatcgatt ggtaattacg ttgtgatcat gccagattat aacgaaaaaa
    20281 tctatcaaac cattaaggca tttttggaaa aaatcgaata tacaggcttt gccaatttcg
    20341 atatgaagta tgatcctaga gatggagaat ataaattatt tgaaatcaat ttgagacaag
    20401 gtcgtagcag tttctttgtg acattgaacg gcttgaatct ggctcgtttt gtcacagaag
    20461 atcgagtgtt caacaaaccc tttgttgaaa cgacctatgg aacgaatcaa tcagataaag
    20521 caagattatg gatgggtgtg cccaaaaaaa tctttttaga atatgctcgg gaaaatgaag
    20581 acaaaaaact agctgagcaa atgatcaaag aaaatcgtta cggtactact gtattttatg
    20641 aaaaagaccg atcaatcaag cgctggttgt tgatgaaata tatgttccat aactatattc
    20701 caagattcaa aaagtatttt catgtgaaag aaggctagtt catggagaat tttttcagta
    20761 ttttaggcgg aatgggcacg atggcgacag aaagttttgt tcgcttgatc aaccaccgaa
    20821 cgaaagctac aaaagatcaa gaatatttga attatgtctt attcaatcat gcaacagttc
    20881 ctgatcgtac agcttatatt ttagatcgat cagaagaaaa tccaatgccg tttctgctgg
    20941 atgatattga gaaacaaaat ttattgcgac caaacttcat tgtgttgact tgtaacaccg
    21001 cacactactt ttttgaagag ttacaagcgg caacggatat tcctatcttg catatgccaa
    21061 gagaagcagc aaatgaactt gtccgtcagc atacgacagg gagagtagcg attctaggaa
    21121 cagaaggaag tatgaaagct ggaatctatg aacgcgaagt caaaaatctt ggtttcgaaa
    21181 cagtgattcc tgatactgcg cttcaagaaa aaatcaatta cctgatctat catgagatca
    21241 aggaatcgga ttatttgaat caagagctct attacgaaat cttagaggaa gcggtagagc
    21301 gcctaaactg tgaaaaagtc atcctaggtt gcacagaatt atctttgatg catgaatttg
    21361 ctgaagataa tcattaccca gtgatcgatg ctcaatctat tttagcggat cgaacgatcg
    21421 aacgtgcatt agctgaaaga agcgaggcat tggatacagc atcggaaaag taaaaaaatt
    21481 ggatttgggg caaatatcct aaaagatatt tggtccaaat ctttttgtaa aagaaaaaga
    21541 aaactggtaa tgatacgccc gggatgatat aattttatta tgcacaatgt gagaggggtt
    21601 cgtaaatatg acagataatt tgcaattagt catcataaca ggtatgagtg gtgcagggaa
    21661 aacagtagct atccaaagtt ttgaagatat gggctatttt tgtatcgata atatgccgcc
    21721 tcgattgatt ccaaaattct gggaattgat caaagaatca ggtaaagtca caaaaatggc
    21781 tttaggagtg gatttgcgtt ctcgttcctt ctttgaagaa atccaaaaca tgctgatcga
    21841 aatcgaaaat acgaacttca tcgacacttc tatcttattt ttagatgctt cagacgaaga
    21901 actagtggct cgctacaaag aaacaagacg agcacatcca atggcgatgg acggtttgat
    21961 cactgaaggg atacgtaaag aacgggcgat actagacgac ttgaaagccc aagcttccgt
    22021 gatcattgat acgacaacat tgacaccacg acaattacgt gaaaaaatca atgagtcatt
    22081 caaatcaaag ggagaccaag gatttcggat cgaatttgta tcatttggtt ttaaatacgg
    22141 gttgccgatc gattcggata ttgtgatgga tgtgcgtttt ttgcccaacc ctcattatat
    22201 cccggaacta agaccattga ccggaaaaga tcagccagtc tatgattatg tgatgtcctt
    22261 tgatgaaacg caatcattct accataaatt tttggatctt ctggaaactg tattgcctgg
    22321 atacattaaa gaaggaaaaa gcagcttgac agttgcaatc ggctgtacag gcggtcaaca
    22381 ccgttctgtg gcattgactg aacgtttggc aaatgcttta gggaaaaact ataaagtcaa
    22441 tgtgacacat cgggacaagg ataaaaggaa agagacggtg aaccggtcgt gaaaatgaaa
    22501 acctaccgga taagaaaacc aaagatcgta gtggtcggcg gtggcactgg tctgccagtt
    22561 atcctgaaaa gtttacgaaa tcaaggagca gatatcacag cagtagtgac tgttgcagat
    22621 gatggtggaa gcagcggtgc aatcagagaa tcgatcgcta tggctcctcc tggtgacttg
    22681 agaaatgtct tagtggcgtt atcggatatg ccacaattct atgaagatat tttccaatac
    22741 cgtttcaaaa aggaagatca gtttttagcc aatcatacga tcggtaatct gatcattgcc
    22801 gcagtttccg agatgcgggg aagcacttat gaggcgattc aattattagc aaaaatgatg
    22861 catgtagatg gacatgttta tccttcttca gaaactcctt tgaccttgca tgctgttttt
    22921 aaagacggaa cgactgcagt aggagaatct aaaatcgcga tcaaccgtaa aaccattgac
    22981 cgtgtgtatg tctgcaacac aaatgataaa agtgaagcca aagcggctcg aaaagtcgtt
    23041 tcagcaatta tggacgccga catggtcgtt ttgggacccg gaagtttatt caccagtatc
    23101 cttccaaatt tagtgatacc agaaatcggc gaagcaatgc tcaagacaac tgctgaaacc
    23161 gtctatatct gtaatatcat gacccaaaaa ggggaaacgg aacatttcac agatgccgat
    23221 catatacgtg ttttacacaa gcatttgaat cagcctttta tcgatacagt attggtcaat
    23281 acggaaaaag tgcctgaaga ttatatggac ccagagatct atgatgagta tctagtacaa
    23341 gtcgcacacg acttcaacgg attgagaaat gaaggatgtc gagtgatttc caccgacttt
    23401 ttagaattga aagatggtgg tgtcttccac gatggagaca aagtagtaga agaattgttc
    23461 cgtttagttt tcggttcaaa atattaagca atttattgtt ggagaaagga ggagaatagg
    23521 atgtcatttg ctgcagatgt gaagaaagaa ctaactggtt tggaagttca tcgagaacat
    23581 gcgaaagcgg aattagctgc tttgctgcga atgaacggct ctttaggtat tgtgaaccag
    23641 cagtttattt tgaacgtcca aacagaaaat gctgcaattg ccagacgtat ctattctctt
    23701 ttgaaagatc attatcaggt acgaagtgag ctactcgttc gtaaaaaaat gaaattaaaa
    23761 aagaacaatg tctatatcgt ccggttgaag caaggcacaa aagatgtgtt gatggatctt
    23821 gatatcatgg atggtatgat gttcaatgga cacgtttcgg acgagattat gggaaattcg
    23881 caaaaaatgc gttcttactt acgtggtgct tttatggcct caggttcagt caataatccg
    23941 gaaacgagtc gttatcattt ggaaatattt tctatttatg aacagcataa ccaagacatt
    24001 tgcgatatgt taaattatta cggtctacat gctcgaacgc ttgaacggcg caatggctat
    24061 atttcgtatt taaaaggagc agaaaaaatt gctgatttct taacattgat tggtgcaacc
    24121 aactcaatgc tccgatttga agatgttcga atcgtacggg atatgagaaa ttcggtcaat
    24181 cgtctagtca attgtgagac agcaaatctg aacaagacga ttgatgcggc ttctaaacaa
    24241 atcgaaaaca tcgaattgat cgaagcaaag gtcggtctac atgcccttcc tgaaaaactt
    24301 caggaaatcg cagaacttcg gcttcaacat ccagaggtca gcttgaaaga attaggggaa
    24361 atgattccct caggtgcaat atcaaaatcg ggaattaatc accgaattcg caaaataaat
    24421 gaatttgcgg aaaaactgcg tgaagaagca gtttaatcca aagaaaaaac tgatacatga
    24481 agcaggagat gcgaatgtat cagtt
//
LOCUS       DAJSMK010000032        24435 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.032, whole genome shotgun sequence.
ACCESSION   DAJSMK010000032 DAJSMK010000000
VERSION     DAJSMK010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.032"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..844)
                     /locus_tag="ON488_001329"
     CDS             complement(<1..844)
                     /locus_tag="ON488_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR3231530.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDS"
     gene            complement(1068..3008)
                     /gene="thrS"
                     /locus_tag="ON488_001330"
     CDS             complement(1068..3008)
                     /gene="thrS"
                     /locus_tag="ON488_001330"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HCR3231531.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3345..3524)
                     /locus_tag="ON488_001331"
     CDS             complement(3345..3524)
                     /locus_tag="ON488_001331"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HCR3231532.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3571..5394)
                     /gene="cadA"
                     /locus_tag="ON488_001332"
     CDS             complement(3571..5394)
                     /gene="cadA"
                     /locus_tag="ON488_001332"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCR3231533.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5672..7951
                     /locus_tag="ON488_001333"
     CDS             5672..7951
                     /locus_tag="ON488_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3231534.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVNEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8044..8691)
                     /locus_tag="ON488_001334"
     CDS             complement(8044..8691)
                     /locus_tag="ON488_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231535.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8870..9589)
                     /locus_tag="ON488_001335"
     CDS             complement(8870..9589)
                     /locus_tag="ON488_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3231536.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9720..10871)
                     /locus_tag="ON488_001336"
     CDS             complement(9720..10871)
                     /locus_tag="ON488_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HCR3231537.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11088..11828)
                     /locus_tag="ON488_001337"
     CDS             complement(11088..11828)
                     /locus_tag="ON488_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3231538.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11832..12155)
                     /gene="rsfS"
                     /locus_tag="ON488_001338"
     CDS             complement(11832..12155)
                     /gene="rsfS"
                     /locus_tag="ON488_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HCR3231539.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12212..12805)
                     /gene="yqeK"
                     /locus_tag="ON488_001339"
     CDS             complement(12212..12805)
                     /gene="yqeK"
                     /locus_tag="ON488_001339"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HCR3231540.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12789..13439)
                     /locus_tag="ON488_001340"
     CDS             complement(12789..13439)
                     /locus_tag="ON488_001340"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HCR3231541.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13449..13760)
                     /gene="yhbY"
                     /locus_tag="ON488_001341"
     CDS             complement(13449..13760)
                     /gene="yhbY"
                     /locus_tag="ON488_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HCR3231542.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13776..14885)
                     /gene="yqeH"
                     /locus_tag="ON488_001342"
     CDS             complement(13776..14885)
                     /gene="yqeH"
                     /locus_tag="ON488_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HCR3231543.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKENKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14882..15409)
                     /locus_tag="ON488_001343"
     CDS             complement(14882..15409)
                     /locus_tag="ON488_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HCR3231544.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15589..16374)
                     /locus_tag="ON488_001344"
     CDS             complement(15589..16374)
                     /locus_tag="ON488_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HCR3231545.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16367..17236)
                     /locus_tag="ON488_001345"
     CDS             complement(16367..17236)
                     /locus_tag="ON488_001345"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HCR3231546.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17237..18616)
                     /locus_tag="ON488_001346"
     CDS             complement(17237..18616)
                     /locus_tag="ON488_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HCR3231547.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18624..19043)
                     /gene="fabZ"
                     /locus_tag="ON488_001347"
     CDS             complement(18624..19043)
                     /gene="fabZ"
                     /locus_tag="ON488_001347"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HCR3231548.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19068..19544)
                     /gene="accB"
                     /locus_tag="ON488_001348"
     CDS             complement(19068..19544)
                     /gene="accB"
                     /locus_tag="ON488_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HCR3231549.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19547..20782)
                     /gene="fabF"
                     /locus_tag="ON488_001349"
     CDS             complement(19547..20782)
                     /gene="fabF"
                     /locus_tag="ON488_001349"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HCR3231550.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20801..21538)
                     /gene="fabG"
                     /locus_tag="ON488_001350"
     CDS             complement(20801..21538)
                     /gene="fabG"
                     /locus_tag="ON488_001350"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HCR3231551.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21550..22467)
                     /gene="fabD"
                     /locus_tag="ON488_001351"
     CDS             complement(21550..22467)
                     /gene="fabD"
                     /locus_tag="ON488_001351"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HCR3231552.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22574..22798)
                     /locus_tag="ON488_001352"
     CDS             complement(22574..22798)
                     /locus_tag="ON488_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HCR3231553.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22851..23813)
                     /locus_tag="ON488_001353"
     CDS             complement(22851..23813)
                     /locus_tag="ON488_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HCR3231554.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23823..24263)
                     /locus_tag="ON488_001354"
     CDS             complement(23823..24263)
                     /locus_tag="ON488_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3231555.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6684 a         5440 c         4249 g         8062 t
ORIGIN      
        1 tcgaatccat aaaatattct tggattgctt ctcgtgtttt tttcactttt tcgctaagct
       61 tttcgttttt agccatatag aaataaaaaa tgatatcgat cgtagcaaat tgggccaaaa
      121 gtgaattagt tgccgcactt cgattcgtga tttcttttgg tctagatgtt tgtacgagta
      181 catcggctat cttgctaagc gggttatttc caaattgcgt caacgcaatg atttcgatat
      241 tcatgctttt cgccagctcg gctaatgcga ctacatctgc acttctacct gagtttgaaa
      301 caagccaaag cactttcttt ttctcattgc tgacaagttg cgggagcaag acgtggatat
      361 ctttttcaaa aatgattggc ttaccgacac gagaccattt ttgcagaata tcttctacta
      421 ctaaagaaga ggcgccaacc ccatataaaa aaacagtctc tgccgattcc aaacactcta
      481 cgactttttg gatcgtttct tcttctagaa tatctactgt ttcttttatc gctacttgtg
      541 cattgttacc aagtttgttt ttgatagagt aaaaggactc atttgcttct atatcactaa
      601 aaccttcatc gattccagtc tgtagttctg ttgaaatcgt gattttgaag tccgtcagac
      661 tttgaaaacc gatttttttg gaaaaacgta caactgtcgg cgcactcaac ccggaagctt
      721 ctgctaattc attagctgtc attgtaggga ccttctcaat attaccgata atgtagttgg
      781 ccaacttttt ttctgctgaa gaataatctt ccatcatact ttcaatacga ctaattacgc
      841 tcataagttc ctccaccctt ttaatgatag tctatgtaag tataccatat cagaccctta
      901 ttcacggtcg tatactggat aaaaaacaaa aaaacaatcc gcccaacaga atatcttatc
      961 ccatcaatcc cacagattct attgagcatc tgtgtctttg aggaatacct gttatctatt
     1021 gttcggattg ctttctatct actacttttt tacaggaaat ttacctatta gttttctctg
     1081 ctgtaatttt tgacttctgc ttccatagca tcaataaaga tattcaaatc ttctacagct
     1141 gtttctttac ttccataacg acgtacgttc actgttgcat cttccaattc cttgtctcca
     1201 acaactaatt ggtaagggat cttttgtgtt tgagaggcac gtatcttata gcccattttt
     1261 tcattacgat catcaacttc tacacgcaac cccttcattt gcaaacgttc tttgatttca
     1321 taagcataat cgccatgtgc atcaacagaa acagggatga ttgttgcttg tataggtgcc
     1381 aaccatgttg gaaaagcgcc tttgtatact tctgttaaat aagcgacaaa acgttccatt
     1441 gtagaaacaa ttccgcggtg gataactact ggacgatgcg tattttcccc gtcttctcca
     1501 acatatgtca aatcaaagcg ctctggcaat aagaagtcta attgtatagt tgataatgtt
     1561 tcttctgtac caagagctgt tttgacttga acatctagtt ttggtccgta aaaggctgcc
     1621 tcgccttctg cttcaaagta atctagttct aattcatcca tagcggcttt cagcattgct
     1681 tgggcttttt cccacattgc gtcatcatca aaatatttat ctgtattgtt tggatcgcga
     1741 tagctcaagc ggaaacgata atctgtaata ttgaagtcag catatactgc caccatcaat
     1801 tcaagcgtac gtttaaattc atctttgatt tgatcaggac gaacaaatgt atgaccatca
     1861 ttcaacgtca tttctcgtac acgttgtaaa cctgacaaag cacctgattt ttcatagcga
     1921 tgcatcattc ctaattcagc gatacgaatt ggtaattcac gataagaatg gatcgtgttt
     1981 ttgtagacca tcatgtgatg agggcagttc attgggcgaa gaacaagcat ttcgccatct
     2041 cccatatcca ttggcgggaa catgtcttct tgataatgat cccagtgtcc agatgttttg
     2101 tacaactcaa catctcccat tattggtgta tatacatgtt ggtaacctag actaacttct
     2161 ttgtctacga tataacgttc gatcgtgcgt cggattgttg ccccttttgg aagccagaat
     2221 ggcaaaccag aacctacttc tggggaaacc atgaacaagt caagttcttt tcctagttta
     2281 cgatggtctc tttcttttgc ttcttcacgg agacggatat attctttcaa agctttcttg
     2341 tcaaaaaagg ctgtcccgta tacacgttgc atcatttgat tgtttgagtt tccacgccaa
     2401 taagcacctg ccactgataa taatttaaat acttgtatac ggccagtgga tggaacatgt
     2461 ggtccacgac acaaatcgat gaattcgcct tgttgataag cagtaatcac ttcttcttct
     2521 ggcaattcac taatcagttc tactttgtac ggatcacttg caaaaatttc taatgcttcc
     2581 tgttttgaaa gaacacggcg ttcgatcggc agattttctt tgacgatttt catcatttct
     2641 gcttcgattg ccggcaaatc ttctgcagtt acttggtttt gtccattatc tgtatcgtag
     2701 taaaaccctg aatcgatagc tggtccaacg ccaaagtgga tatttggata gaggcgacgc
     2761 atggcttggg ccatcaaatg agctgctgaa tgacggacta agccaagtgc atcttcatgg
     2821 tctggtgtga tgatctcaat acttgcatct tcctcgattg gacgagtcaa atcaacgagt
     2881 tttccgttca ctttaccagc taaagctttt tttgctaagc tttttgaaat gctttcagca
     2941 attgccaatg ttgttgttcc agactcaaat tctttgactg caccatctgg aaaagtaatt
     3001 tttatcataa tagtttcctc cttgaaatgt tttgattgat cagatcatca agctgaaaaa
     3061 caaaaaaatc ctagcatctc ttgaaaagag atactaggac gaaaagttcg tggttccacc
     3121 taatgttcaa acgcaaatgc gttcctcaag cgttgtaacg gtccgaccgc ccttgcttca
     3181 acaagggttt cgaaagtggt catcctttgg ttttctcctg gaaaagtttc agcctagctt
     3241 ttcctctctt atcgaagact ctcaaattca gttggctttc tcatcaatca attatgtgtt
     3301 tatttaacca ctaataaata gaaaaatcaa gtgggaaact aaacttattt tttccattcc
     3361 ccatttacac cgtatgttcc ttttttcatc tcattgatga tgacatggat gtgttctttt
     3421 ggtgcctgcg tgtttttatg aacagcttcc gtgatatctt tcatcatatt ttctaattgt
     3481 tccggactgc gaccttctac taattcgaca tgtacgaatg gcataatgct ctctcctctt
     3541 tctgatcgtt cttttttcaa ctcgattcta tcatactatg tttgtcttgg gtactgaatc
     3601 aggaaaaatg gctggatctt tttttgctct caaggcactc aaaatagaga ccgtatccac
     3661 gacttcttgc aaaacagctc cgaataatgc ggggattagt cccgtacttg caattaacat
     3721 caaaaaaata caaataaaga tgccaatcag tacagactgt ttcgctattc tcatcgtatc
     3781 tcttgaaatc actactgctt ttgctacacg caagagatca tctttcaaga tgaccgcatc
     3841 tgcactttca ctagcagctg tagaaccatg agcccccatt gcaataccga tatctgcagc
     3901 agcaagtgct ggtgcgtcat tcacgccgtc tcctaccatc gcaacaggtc tttgatcttt
     3961 agggatactt tctaaaatgg tcagtttatc ttgaggcaag ctacgggcat gtacagaatc
     4021 taattggact ttttctgcaa tcgtttgagc aatggcagat ccatccccgg tgatcatcat
     4081 caaatttttc acatcaagtt ttcttagctc cttgattgtc tttgctgctt ctgggcgaat
     4141 ctgatccgaa aataggatcg ttcctgcaaa agatcgatca attgttacat agattgctgt
     4201 attggacgtt tctatttctt cagctgaaac aaaagaggca cgtccaatct ttacttcatg
     4261 attattgact actgcttgga ttccttgacc ggtcacttct ttcagttgac taacaggata
     4321 cagttggctg tttttcacgt tgttcactaa cgaacgagct aagatatggc tagattcctg
     4381 ttctgcacta gctgcataca gaagtagctc ttcttttttt attccattga ctggctgaat
     4441 cgcctctact tccaatatcc ctttggtaag cgttcctgtt ttatcaaaag caatcgtttt
     4501 tgtacgtgcg agcttttcaa tcgttgttcc agtttttaca acgatcccgt ttttacttga
     4561 acggctcatt cctgcaacta aagcaatggg cgcagctaga atcagtggac aaggtgatgc
     4621 cactaccagt acctcagcaa atcgtaaagg gtcttttgag aaccaccaag aaataccacc
     4681 gatcaaataa gcaatcaacg tgaaagggac tgcataacga tcagctaaac ggacaaatcg
     4741 ggcaggcttt tcttttgatt cttcgactag tttaataatc atttgatact ggctgtctgc
     4801 ggcacgtttt tcagcgatca tttggatcga tccgtctcca tttaaagacc ctgacataat
     4861 ctgatctcca ggtttcttgg tttccgggcg ggactcacct gtcaaagaag attcatcgac
     4921 cgaagattct cctttggtca ctcgaccatc tgcgggtaca agttcgccag gcttgactag
     4981 taactggtca tcaatattta tttcatcgat tactatatcc tgcaattttc cttctttgaa
     5041 tcgatgggca attcttgggg tgttatctaa caaagactgc agttctttac ccgctcgttt
     5101 attcgcgtaa tcctctagac tatctccgcc cgtaagcatg atcaatatca tcaaactagc
     5161 ccagtattct ttgacggcta atgttgcaag gattgcggta atcgctaata catctacgcc
     5221 atatcttcct gaacgtaacg tcttgatcat ttccaaaaac atcaagaagg cgagaatccc
     5281 tccagtaaat gcgacaatcg caaatgcaag ggccggctgg tgaaaaacaa attcacttaa
     5341 taaagctatc ccaccaataa gcaaagtaag taaaaatttt ttgaaatgtg tcattgtttt
     5401 ttctcctctt ttatgtgact tagagaggtt agtaataaat ttccagctgc ctctttcatc
     5461 ttaagcatag tccttgacta gcacttttta aaacaatagg ccttaattga aaacaactat
     5521 cactatcagc gtttccaaaa ttcatcagtt ctacaaacaa aaatattcag caaggattac
     5581 tttttcgatt catcagttaa aaagtacctt ttttcgaaaa actatgctat acttttaatt
     5641 cgttatttac ggcggaagga gcaaacatgc gatgaatgag aaacaactag aacaaacgca
     5701 cgtggatgaa acgatcgaac taatccagat cgaacaaaat atgctggata caaaacaaca
     5761 agaattgact caggaaatga atcattcgac aaaagacaca gctaatcaca agattcgagc
     5821 tggttccaat gaagcttttt atgaatctgc tgttgaatat cgccaacatg agcaggaatt
     5881 gcttttgaaa taccatactc ttgaagcaca gcaaaaacgc ctgcaaacgt tgtctgtcat
     5941 gaaagatagt ccttattttg cccgtatcga ctttaaagaa gaccgtgaaa cagaaacatt
     6001 atatctaggt atcgcttctt taagagatct ggcagaagaa acaatcgtta ttgactggcg
     6061 cgcaccaatt gccaatcttt attatgaagg tgagattggt cccgcatttt atgaaactga
     6121 aacagataga atagatgtcg atctgcagtt gaaacgacaa tttaaaatcc aagaaggacg
     6181 tattttatct atggtagata cgtcggaagt aatcaatgat gactttttgc tagagatatt
     6241 ggatgaatca tcaagcaacc atatgaaaaa catcgtctct acgatacaaa aagcacaaaa
     6301 tgcaatcatt cgggacacaa caagtaaagt aatgctgatt gaaggaatcg ccggaagtgg
     6361 aaagacatcc gctttgcttc aacgtattgc ttttctgttg tatcataatc gcaagtggct
     6421 cgaggctgaa aacgttcttc tattttcacc caaccatttg ttttctgatt acatctcgac
     6481 tgtattgcct tcattaggtg aaagcggcgt gcctacacag acattcaaaa attatttggt
     6541 gcagctgctg ccagagtttt ctttactaga tgaacagcaa caagaaagtg gttttttgct
     6601 aggggaaaaa gatccgatac aagtgatgaa aagcggattg accttagtcg atcagattga
     6661 tcgctatatc caaggcatca caaactacgg tcccttgttc cgtgatatga aaataaatgg
     6721 ccgtacgatc ctatcaaagg aatcgattcg ccaatggtat aaagaaacaa atgaacaatt
     6781 acctttacat catagacttt ctctattaca aacgaagctc ctgaaaaaat taggcggtct
     6841 gcaaaaagac gaaacacgtc agcaatgggt caaagatctg gcggaagaac agctccaaga
     6901 actatacgca acagatccaa atcttgaata tacagaacaa aaggagcgtt cattacgtaa
     6961 aaaactggcc aaccaaatcg tacgtaaaag attccgtcga atccatcgag ggatcatgaa
     7021 ttatcaattt gtcaatataa cgaaacaata tctccacttt ctacaaactg tgccactttc
     7081 tcttctaaca cgacataaaa tcagcgagac caggtggcag gaacatttga caactgttcg
     7141 tacacacttg cgtcaaagag aattgcgtca agaggatgct gtactattct ttttactgat
     7201 gcgccgaaca tatccagtga cggttacaca caaagctcgc tatatcttta ttgatgaaat
     7261 gcaggatttc gcaccatcac aagtggcatt gctgcaagcc ttgttcccaa aagcaaattt
     7321 gactttctgt ggagatctaa atcaaaatgt ctttggaaat gaaacgatcg ttggatcatt
     7381 ggaagacctt ttcgtggacc gtgaagtcac tcgtttccaa ttaacgacaa gctatcgctc
     7441 cacaaaagaa atcactgatt ttgctaatca ttttattgtg aacgaacatc aagtagaaac
     7501 aacagcaaga aaaggagacc ttcctttgct catccaagga acaacagatg atatcaaatt
     7561 gaattggtta gcagatacca ttcgaacgac tcagggaaaa gcccggtatt ggcgtacagc
     7621 aatcatagct aaaacacaag aagaatgcga agctctttat gctcaactgc cagacgagtt
     7681 gaaacaacaa gtccagctga ttttaaatga gagtgacttt atgaagcgtt ccattatttt
     7741 acttccagcc tttttagcaa aaggtctgga gtttgaccga gttttcttgt gggatgtaga
     7801 tgcagaacat ttttcttctc agcaagacaa attgatcctt tacaccatgt gtacacgtgc
     7861 gatgcatgaa ttgacccttt ttacctccaa taatgaaagt cctttgttaa acaatatgga
     7921 tatttcatct tatgagaaaa aagtactgta agtaaaaaga caactgctat cattaatgtt
     7981 agcagttgtc tttttattta caataataat tgcagaaaaa gtaattcaat catttaaggt
     8041 catttattct atatataaat ccaaatctgt ttcaggatat tttaatttga caagcgaaat
     8101 aatcattttc agttcttcca tgttttctgg atattctggg tcaaatacct tgctatgacg
     8161 gccaatcccg ccattgtcga tcaatcggta aattcgattc cattcaatga attggtcaat
     8221 tgattggaaa ttgctgattg gatagccgcc acaatccaaa atctctgata cacgaaatgc
     8281 taggtatgca ctatcgatca ctttattttt tttcgtgtct atcttctcat ttctttcgat
     8341 aagaattttt tcaggacgat gtttcaagct ccactctaat agtagaaaga aagcctccat
     8401 ccgatactct tcttcaaata accgaaaggc tgaatcagaa cgacgaaaaa gcagcggaat
     8461 cagataattt tgtctataaa tcagcattgg tgcgcggtcc accatacact ctaaataacg
     8521 gttcagatac cctgtaccga catagtttcc taatcgatag ccttcaacgc cgaatcttgc
     8581 gtatttttgc gctaattttg aacaatcagt tacgttcaca gctaactctt ctactttgcg
     8641 gtaaccgctt aagatacgtt caaaaggttc taaagtgatt tttgcttcca tattcttccc
     8701 cgtccatctt ccacatactt catatcattt cacatgatac ttatgctctc atcataccac
     8761 aggttgaatt agaaaagaaa ataaatcaca caaaaaagca agacaatctg ttagtgagat
     8821 tgtcttgctt ttcgaaaaag actgaatact tttcgttaaa actggttgct tagtcttcta
     8881 atgccacatt atggaacaca tgctgtacat cttctagatc ttccagtgca tcaatcattt
     8941 tttcaaatgt ttcttgatct tctggagata gtgttacctc gttttgaggg atcatttgga
     9001 tctcagcgat tgaaaaatca gtgattcctt tttcttttaa tgcttcttgt atactatgga
     9061 aatccgctac ttcaccgtaa acgatgattt gtccttcttc ttccattaca tcgcgaacat
     9121 cgatgtcttt ttccattagg tattcaagga tctcgtcagc gtcttctcct gcaaaagcaa
     9181 agattgctgt attgtcaaac atgtaagaaa ccgctccgga aacacccatg ttcccgccat
     9241 ttttcccaaa tgctgcccgt acgtctgctg ctgttcgatt cacattgttc gtcaatgtat
     9301 caacaatcac cattgagccg cttggtccaa atccttcata gcgcaattca gagtatgttt
     9361 catctcctgc accttttgct ttttcgattg ctcggtcaat aatatgtttt ggtacattat
     9421 aagttttagc gcgatcaatg acgaaacgta gtttttggtt tgcatgcgga tcaggatcac
     9481 ctgattttgc tgccgcgtag atttcaatcc caaattttgc ataaatccgg ctattattag
     9541 catctttagc agttttcttt gctacgatat ttgcccattt acgtcccata ttttcacttc
     9601 gctttctgat ttgatagttt cataacgcaa aaacgtcctg ttccattata cttgtgaatc
     9661 acgattctgt gaagcttttt ttctttcttc cttcattctt ctcattttta gtcaattatc
     9721 tatactcgga ttgggatttg cccgaaattc tgttccggaa tattgcctcc caattgatag
     9781 atttgatcac ttctaactaa cagttccgct tcttgtgcct ctttttttcc gattcgggaa
     9841 taaatagaaa tctctttttt ttcttttaag aatcttcttc cagcatcggt aaatccaagt
     9901 agtcgaagat aatttttatt ttgttggaca ggaatctctt gctttttgat attcagcaag
     9961 acataacaag ataatcgttg gatccgtgtc catgtatatc tttttgtttt tacctttgac
    10021 acaaaatcct caaaactatc agcagttgca gctgctgttt tcatgcgcga ttctattcct
    10081 tcggtcatct gatagatatc tgtcagttcc agcaaagtag aagataacaa ccgataacgc
    10141 aaatacggcc aataagattc ccaagtctgc agcgaacaag ttgaaagatc ttcttctgtc
    10201 tgaggcggca caagtccagc tattcttttt ccttcttcta acgcatggcg aatggctgtt
    10261 gcactggcta tcctctgatc tgtgatgatt ttttcatgat agcctgcact tttacgtcgg
    10321 atcggatgta attccatagg gtggacatac ttggcatttt cctttgcata acttaatccc
    10381 aagatatgat ttggcgaaga aaaatcaagc gtaatatcgg gatacagact gcgaaaaacc
    10441 tcagtcattt tttgcggata actatacgtt tgatcagaca gttcttgaaa tgcctcttct
    10501 atcctatctt gattctcttg gacaaagcgt ccgaaactgc tgtaatcaaa cgaagtctct
    10561 tcttctgttc caaaacacaa actgtcacag tccagtgttt gcaagatttt tactgcacct
    10621 ttagcaaaat agtcagctga ctgaaccgcc cattcgacgg gaagctccac tactaaatcc
    10681 acaccatttt gtaaagcttc attcgcgcga tgccatttat cgatgatagc cggttcgcct
    10741 ctttgcaaaa aattcccgct cattacagca atgacgacct ctgctcctgt tatttttcgt
    10801 gccatttcca catgatagcg atgtccattg tgaaaaggat tgtactctac gataatcccg
    10861 cagcttttca tgcgcatcct ccttcatagt tatcgataaa aaagaaatag agacaagtaa
    10921 aaaaaggcaa aaatcggaaa aaatacccga actatataaa ctattctcgc aaacacaata
    10981 cttctgcgac gaaaagctgc actgcaagag caatgcctat atcgttcgga tatataattt
    11041 atgttgaaga tttattcttt tcttgttaac tcgagcaggc aaaaccgcta gtctttgtat
    11101 gctacaaaga accagcgctt tgatttctct gatgctgctt cgtctgtaaa atcagaaaat
    11161 gcttcgactt tcgaaaagcc gctgttttcc agcattctta aataactttc caatggatag
    11221 gtacgctctt gatgtagttc atcttcacga ataaatcgac cagacccttc ttgttcttca
    11281 acgaaaaagg taagaaaatg ttcgatgctg tgtttctcgc ttcctggata actatcccac
    11341 aaaaaagcaa aattatcccc ttgataatga tagctatatt ctggaaaaac ctcatctact
    11401 tgataggtgg agtgtacgtc aaataaaaat cggccatttt cttctaacgc ttgatagact
    11461 tcatcaaaca cttgctgtac ctcttgtcta tttttcatat agcacagcga atcagaaaaa
    11521 caggtaattg cctgatattg tccgatttct gataaatcga gcatattgcc ttccacaaat
    11581 tggatcgatg cgtcttcttc atatgctcgc tggctggcaa tcatcaacat ctcttctgaa
    11641 aggtctaacc ctgtcacttt atatccatct tttgcaaagg caaccgctaa tgctccagta
    11701 ccgcatgcca gttccaaaat attttttgtg tcttcttgta aatgacgttt cgaaaaagct
    11761 aaccattgct gataaagtgt ttcgtccatc acttcatcgt aaatgaaagc aaatgtttca
    11821 taagccatat gttaatccaa ccattcacta agatcgacta gcggagcatc tgaccatagt
    11881 ttttccagat tatagaaatt tcgttctggc gcatggaaaa catgtacgat cacatctcca
    11941 agatcgatca atacccattt tccgccttct tttccttcaa tacgttttac ttcatatttg
    12001 ttttcttctt ctttatcaat gatttcttct gtaattgcgt tgatttgacg ttcgctattt
    12061 gctgaacaga tcatgaaata atctgccaac aaggaaacat ttcgaacgtc taaagcgata
    12121 atgtcttctg cccgttttga atctgctgct tcaatcgcaa tttttaattg ttctttacta
    12181 tctatgatga tttcctccta atatgagcag cttatttttt tgctacccag taattatatg
    12241 tttcgattgt ttttggataa atctgttgtt cttgcgcaag caaatgggcc aatgtatgtt
    12301 ttgtttcaaa tgctacagct tcgtctagat cagcccatgc aatggctcgt gcatcttgta
    12361 ccccaggaaa atctcgacct ggttcaatat agtctgctac ataaatgatt ttgtcaagga
    12421 gactcatctt agcagcccca gtcgtatgca cccggattgc atgaagaatc tctgcatcgg
    12481 tgattcctaa ttcccgctct acaaacgaag cgccaacaag accatgccag attgcattat
    12541 tataattcaa taactccgga tcaaaaccgt ctcttacgat taccattttg aactcctcat
    12601 ctggtcgttc ttttgcataa tcatgtgtca atgcagcaat actagctttt tcaggagaag
    12661 caccgtattt tttggcaaga gccacggctg tttcttctac tccaagcaca tgcttgaagc
    12721 gttgttcgct cattctcatc tgtatttttt gcatcaggtt ttctctagaa taagcagtat
    12781 attcattact atagtccata ttcatacaac ccttcatttt gaatataatc aattacttta
    12841 tctggaacaa ggtagcggat agaacagcct tctttgatct tttgacgtat tttcgtggaa
    12901 ctgatgtcga tctcaggtac atctacccaa attacaggat atggagtatc cgttgtgtat
    12961 cctggtcgac gtatacccac aaagttgacc atagaagtca gctcatcgat tttataccat
    13021 tttggcaaat attctaccat atccccaccg ataataaagt aataatctgt atccggattg
    13081 ttttgcgtca attccttcat agtatcatag gtgtaacttt tcccaccacg agctaattca
    13141 atcgtttcaa tctgcaaaaa aggattgtct tccaccgcta attccaacat gttgagtcga
    13201 tgttttgcat caatcgtctg tttctcatca acatgaggtg gctgataaga aggcatcaaa
    13261 aatacgcggt caagacctaa attccggcca gcttgttcag ccatcactaa atgtgcaagg
    13321 tgaacgggat tgaatgttcc gcccaagatc cctacttgct ttttcttctc taagaattga
    13381 ggcatttctt caggaaataa ttgtgaacga acaaatgtct tagcttgcgt attcatcatg
    13441 gtcactcctt atattgcttt tacttctttt gatagccttt gatacttttc ttttgtggaa
    13501 ggtttgtata atacaataac acgtccaatg atttggacga tttcgcaatc tatttctttt
    13561 tctaatactt gagctgcttc ttctgcaatc tcatctgtat tttgaagtaa cgatactttg
    13621 atcagttctc ttttttctaa agcttcttca atttgaacga tcattgctga attgatccca
    13681 ccttttccga tttgaaaaat cggctgaaga tgatgcgctt tgctacgtaa aaaacgcttt
    13741 tgttttcctc ttaaactcat aattttcctt cttccttaaa tcaatgcttt gcgtttcaat
    13801 acatctacac cctttggcgc ccagcccgca attactactg gcgctgttac agtgatccag
    13861 cctagaccgg caaaaacgat gtctgttttt tctttcacag aaaactcaaa acgaacaagc
    13921 tccggaaatg cctcgacttc atcaggacga ggaggctgta ataatccacc tacatgtttt
    13981 tgataaaatt cgtctgcttt ttccagtttc gttcgatgaa tatttacatc atttgacaca
    14041 taagcaataa atgaagcacg attgccgctg ataaaatcaa atcttgcaag tccgcccaag
    14101 aaaagtgttt gcccttcatt cagctgataa actttaggtt tgttttcttt taacggtgca
    14161 atgatccgca aatctttttt acctaagtag tgcgccattt gatggcgatg gataattccc
    14221 ggtgtatcaa tcaaaaaatg cccgtcatct aaaggaatct cgattttatc caaggtcgtt
    14281 cctggaaact gcgaagttgt gattacatct tgtactcccg ctgtattttt gatgatttga
    14341 ttgataagcg tcgattttcc gacatttgtt actccgacga tatagacatc ccgtccatcg
    14401 cggtattctt cgattttttc taatagttcc gtcatctcat gagatttctt agcactagtt
    14461 aataatacat ctactggacg aattcctgct tcgtaagcac gttccttcat ccattgtgtt
    14521 aatttagttt ttttcaatga tttaggtaat atatccactt tgttcccaac taaaagtact
    14581 ggattgtcac cgacaaaacg gtgtagtcct gggattagtg aaccattgaa gtcaaaaata
    14641 tccaccacat tgacgatcaa tgcatctttt tgccctaatt cattcagtaa gcgcaaaaag
    14701 tcgtcatccg tcaatgagac atcttgggtc tcattataat ggcgtaatct gaaacaacgc
    14761 tgacaataga cttccccgga agctaaacct ttttccaaag ccgtttgcgg cgtgtatcct
    14821 aattcaccgg gtttgtttgt ttgtataacg gcaccacagc cgatacattg taattcttct
    14881 gtcattcgat tccacctcgc cagcccatat cagggtgttt tgctaataga taggccataa
    14941 ttcttttttc ccaaaaacga ttaaattgtg tcttccaact atctgttgcg ataatgggtt
    15001 ttacaaggat gctacgtatc cctgcacgat tggctccacg tatatcagtc ataatctgat
    15061 cgcctaccat tactatctca tcatctgcta aatccaattg tttctttgct atgttgatcc
    15121 ctcttgctaa aggtttcatt gctcgtgcaa catacaaaag atcaaatttt tcaatcgctc
    15181 gcgcgacacg ttttgaatta ttgtttgaaa caacaacaac agggattcct gcatttttca
    15241 tttctaaaat ccaagtaagc aactcttctg ttccatctgg attattccat gcaatcaacg
    15301 tattgtctaa atcggtcaat actgctttga tgcctagatt ctttaattgg gcaggtgtaa
    15361 tctgatagat ggcttctacc atccatgttg gtttgtaatt tgaaaacatg ctgtctcctc
    15421 atctgcaaaa aatgaaggag cacataaagt actcctcaac cccgtattat actgcatatc
    15481 agcaaaaaaa actacctcta tactcgttcg tctttcagaa aaagcatttc tttacaaaat
    15541 gaccaaaaat aaagattgat cacagaaaaa tttagaaaca aaaaacaact aatattggcg
    15601 gaacctcttg tatcgttttt ccagtaattt atgctgatct aatcgaacaa gttccgtcaa
    15661 tctttcaatc aacgcttttt tcataatgtg tgcgacttta tatcgtggca actgctcgcc
    15721 gttgaacgtt tcaggaataa ctcgatcaac gattcctaac tcgcgtagtt ctggcgcagt
    15781 aattttcatc aactcagctg cttctgcggc gcgactaccg tctttccaca aaatcgacgc
    15841 aaatccttct ggagaaagca cagcataaat cgtttcttcc agcatccaga cttcatccgc
    15901 taaacctaga gcaagggcac cgccacttcc accttcacca atgatgatgg cgatgatcgg
    15961 tacctttaaa tcagacattt cgagcagatt tctggcaata gcctctcctt cgccgcgctc
    16021 ttctgctcct acaccgcaat atgcacctgc tgtattgatc aaggtaatca ccggtctatt
    16081 gaacttttcc gcttgtttca tcagtcgtaa agcttttcga tagccttcag gatggggaga
    16141 accaaaattt ctgcggatat tttcctgcag atcccgtcct ttttgaatac cgatcactgt
    16201 taccggtttg ccatctaatc gagcgattcc accaacaatc gcttcgtcat ctgcaaataa
    16261 acgatcacca tggcattcct cgaaagaatc gaagatctct tcaaaaaaat ccaagcttgt
    16321 ccatcgttct ttagctcttg ctaactgaac gacatcatgt gctgtcttat ccacgatcta
    16381 tccatccttt ctgtgtatgc aattcaagaa gcgtatggat tttctgtttc aattccatgc
    16441 ggggaacaat ctgatcgaca aaaccatgag ataataagaa ttcagccttt tggaaatctt
    16501 ctggaagttc ctgcttgatc gtctgttcga tgacgcgtct tccagcaaaa ccgatcaagc
    16561 tttggggttc tgctagaata atatcgcctt ccattgcaaa actggcagtt actcctccgg
    16621 tcgtcgggtc cgttaaaaca gttagataaa aaagaccttc attgctatgc cgtttgacag
    16681 cagcagagat ttttgccatc tgcattagag aaaagattcc ttcttgcatc cgtgcgccac
    16741 ctgaagctgt gaacaagacg actggaagac tttcctttgt tgctcgttcg aataatctgg
    16801 tgatcttttc tccgacaatc gttcccatac ttcccatgat aaaattagga tccatcactc
    16861 caataatgaa gggaatcccc tgaatggttg ctttaccagt gaggactgct tcatgaagtc
    16921 ctgttttatc ttgcattttt ttaatttttt ccgtatattc gggaaatgct agcggatctt
    16981 tggttacaag atccgtatcc cattcttcaa aacttttttc atcaataatc aaagctagac
    17041 gctgccatgc accgattcga aaagcgtatc cgcaatgagg gcatactttt tcttcaccga
    17101 tgtctttcgt ataaaggata tgtttgcaat ttggacactt tgcccacatg ttatcaggaa
    17161 cagatggcga gttagcaggt ttgctctctc tattaggatt gatccgaata tatttctttt
    17221 tcttaaacag agccatctat gcgcctccta tctccgtttc tggtgtccaa ttcggtaaaa
    17281 attcttcttg taaaaatgct gtgctgtaat cacctgctat gactgcagga tgactaatca
    17341 aatccatctg aaattctgcg ttcgtgatga ttccttctgt gataaattca cttaaggctc
    17401 gctgcatctt cattaatgct tcaaaacgcg tatttccatg gacgattatt tttgcaatca
    17461 ttgaatcata atatggcggg atcgtatatc ccgggtaaac tgcactgtct actcgcagtc
    17521 ccatcccacc tgctggaagc agtaagtttt ggatcttccc tggagaagga gcaaaatgga
    17581 aagcaggatt ttctgcatta atccggcatt cgattgcgtg tccttggaat actacttctt
    17641 cttgacacac attcaaaggc tcaccggctg ctatctccac ctgttttttt actaaatcga
    17701 ttcctgtgac catttctgtt actggatgtt ccacttggat tcgagtattc atttccatga
    17761 aataaaaatc gccttcttca tccatcagaa actcgatcgt tccggcattt tcataattga
    17821 ctgctttagc tgctcgaaca gcagcgtctc ctagtgcttc tctttttgtt tgtgagatca
    17881 ctacagaagg agattcttcc agtacttttt gattgttgcg ttgtaaagaa caatctcgct
    17941 cgcctaaatg aatgacatga ccaaatcgat cacctaagat ctgaacttct atatggcgag
    18001 caggataaat gattttttcc aaatacatat catcatttcc aaatgccgct gctgcttctt
    18061 gctgagctga agaaaaatgc tgtgggagct cttcttttga ttgaactttc cgaatgcctt
    18121 tcccgccacc acctgcagct gctttcagca tcactggata accaattctg tctgctattt
    18181 ccaatgcttc ttctactgta gataatacac cagtacttcc tggaatgact gggacatttg
    18241 cttcttgcat caattgacgc gcattgatct tatttcccat tgcatcgatc gttgcacttt
    18301 taggaccaat aaatgtgata ttgcactctt cacacatgga ggcaaatcgg ctattttcag
    18361 ataaaaaacc aaatcctgga tgaattgctt cggcttttgt cacgattgca gcgctcagta
    18421 cttcctgaac attcagatat gaatcaacgg cttttgccgg gccaatgcag attgcttcat
    18481 ctgctaactg tgtatgaagt gcttcggcat ctgcttctga atatatcgct acggtttgga
    18541 tccctagttc gcggcatgca cgaatgatac gtacagcgat ttcaccgcgg ttagctatca
    18601 atactttaga aaacatattt cacctatcca atcataaagg ttaattccgc ttcggctact
    18661 tttttaccgt ctactttagc gattcctttg cctattccgg ctgaagcttt cactttcaat
    18721 atctcaactt caaggtataa ggtatctccc ggtgtaactt tcttacggaa ttttgctttg
    18781 tccaatccgc cgaaataagc cgtctttccc ttgaattgtt caagagaaag taatgcaact
    18841 gctcctgctt gagccattgc ttcaacaatc aatacccctg gcataacagg ttcttctgga
    18901 aaatgtcctt gaaaaaaggg ctcattgatc gttacatttt tcttagcaac gatccgttct
    18961 ccttcaacca tttcttccac tcgatcaatc aaaagcattg gataacgatg tggaatgatt
    19021 tcttttattt cttgtatgtt cattgttttc cctctttcct gctttgctta tttttgctga
    19081 atcctaaaga gtggctgtcc atattcgaca actgactcgt tttctacaag gatttctgtg
    19141 atcactccgt cggcctcact agttatctca ttcatcagtt tcatcgcttc aataatgcag
    19201 ataacttctc ctttggcaac ttgatcacct acttttttga aagctggttt gtcgggcgct
    19261 ggttgcagat aaacgattcc cacgattggc gaaacaacct cgattccatc aaatactgcc
    19321 gattcttttt ctttcattat ttctggagca gttgttgctt gttcaggtat gacattgact
    19381 ggctccgaaa ctggcaacgt ttcgtttgtt tgaaccatat tcatgcctcg acttgtttta
    19441 tttttattca tatacaattc aaattgacct tcacgcaaat cgaattccgt tagcgaggat
    19501 tgatcaaatt gactgactaa ttctctgatt tcattgatat ccaaaattat tcctcccagc
    19561 gtttcatgca cagaaccgca ttatgtccgc caaaccctaa tgaattactc attgcataag
    19621 taaaacttgc aggtttgctt tcgtttttga caactgtcaa gtcaatctca ggatcttgtt
    19681 tttctacatt gatcgtaggt gggataaatt gatgttctaa tgccagcaaa gttgccaagg
    19741 cttcgatccc gccggctgct cccaataaat gtccagtcat cgatttcgtg ctgctgacgt
    19801 aagtatctct gaaattttca cctaatgcga tttggattgc ttttgcttct gcctggtcat
    19861 tggctggtgt acttgttccg tgagcattga tatatccgac ttgttccggc tgtacaccag
    19921 cttcttccat cgcaagcttc attgctttag atgcaccaga accatctgga gtaggagctg
    19981 tcatatggta agcgtcacag tttgcaccgt atccaacgat ttctccatag attttggcac
    20041 cgcgagcttg tgcatgttct aaagattcaa gaactagaac gcctgctcct tcacccatca
    20101 caaaaccatt ccgattttcg tcaaacggaa tcgaaccacg attaggatca gttgattctg
    20161 agagtgctgt taaagctgca aatccagcaa tccccatctc acaaatcgtt gcttctgttc
    20221 ctccagcaag aatgacatca gaatagccat gtttgatgtt acggaatgct tccccaattg
    20281 aattcgttcc gctagcacaa gctgttacga tagctgtaca aatacctttt gcacctacac
    20341 gcaaagcaat atttccagct gccatgttgg caatcgccat tggtacgaac attggagaaa
    20401 ctcgttttgc acctttttca tgtagacgaa taacttggtt ttcgattgtt ggaagaccac
    20461 cgatcccaga tccgatgatg acgccaaacc ggtcttgatt cattttttct ttatctaaac
    20521 cgctcatctc cattgcttct aaagcagcgt agattccata gatcgaaaac atatccattc
    20581 gtttgctatc ttttttaata aaatatttat cgtaagggaa atctttgact tcacccgcta
    20641 aggtaatccc tgtttctgaa gcatcaaatt tagtgatcgg tgcgatgcca ttcgtcccct
    20701 cttttaagct attcaaaaag ctgtctgcgt catttccaat aggtgaagtg actccatagc
    20761 cagtaattac cactcgattc atttgtttgc tctccttttc ttatccgtgc atgaccaatc
    20821 cgccatcgac attgatgact tgtccggtga tatatggatt ttgtgctaag aaaactgctg
    20881 tttgtgcaat atcttctact tgtccgaaac gctgcatcgg aatttgcttt tccgcttgtt
    20941 ccttgacttt gtctgctaaa acttccgtca tatcagttgt gatgaatcct ggcgcaatgg
    21001 cattacatgt aatgcctcta gttgcagctt ctcgtgccac agattttgtt aatcctacta
    21061 cgccagcttt actagctgca taatttgctt gaccaatatt tccaatcaac ccagatacac
    21121 tagagagatt aatgatggcc ccttctcgct gcttcatcat ttttttcaat acgtgctgcg
    21181 tcatattgaa ggttccaatc aaattgatat ccagacattt tttgaaatct tctgcatcca
    21241 ttcgcatcac aagtttgtca tttgtgattc cggcattgtt tactaacaca tggatcgatc
    21301 caagcttttc ttctgcttct ttgatcattt gtcccgcttt ctcataatca gagatgtcac
    21361 cggaaactcc tacgcatttt acaccgaatg cttcgatttc ttctatcttt tcttttggaa
    21421 tctctccgcg accattcaaa atgatatttg ctccagcttt tgcaaaagct aaggccatcg
    21481 ctttgccgat tcctcttgta ctacctgtga taaatacatt ttttcctttt acatccataa
    21541 cgttcctcct tatagtattg ctattgtttc atcaaatgtc tgcttattct caacacgcag
    21601 aactggtatt gttttatcga tttttttcat aaatccgctt aatacttttc cggggccgac
    21661 ttcgatgact tgttcgatgc cgattgtttt taacttatgg atactctcat agaaacgaac
    21721 aggttgcatg acttgctgtt caagtagtcc cgcgattgtt tctttcttca ttatttccgt
    21781 tgttgtgttg cttatgatag gaaaagaagg ttcagagaat tgaatctgac ttaggtcctt
    21841 cgccagtttt tttgctgccg gttctaaaat agctgtatga aaaggcccgc tgacatttag
    21901 agggatcatt cttttgaacc ctttttcttt taatagtaaa acagcttcgt ctactgcttt
    21961 ttcttcgcca ccaatcacga tctgctgagg tgtattataa tttgcaggag atacgatgcc
    22021 gtacttgcta gcttcatgac agctttcctc gatcgtttca atcggcgcat tcatcactgc
    22081 aaccattttc ccgcttccag ctggggcagc ttctgtcata taagcgcctc tttttgctac
    22141 taacgcaact gcttcagtga aggatagcgc attactagct actaatgccg aatattctcc
    22201 taaactcagt cctaaagctg catctgggat gattccatgc tccttcaata agcgataata
    22261 cgcgatgctg actgttagaa tagctggctg tgtatattgc gtctgatcca aacgttcatt
    22321 ttctgtaaag caaagttcag ccatatcgta gccgagaatc tcacttgctt catcaaatgt
    22381 ctgctttaca acggcttctt catataaatc ttttcccata ccttgatatt gtgcaccttg
    22441 gccactaaat aagaatgctg ttttcatgtt tttctccaat atatccagaa tatatgtttg
    22501 attcttccta ttcaaaaagg ccgagacatt cctatttcag gaaatgtccc agcccccaac
    22561 ctaattttaa tgattatgca gtttgttttt ctacgtaagt cactaaatct tgaaccgttt
    22621 tgattccgtc ttctgtttcg attttcacgt caaattcatc ttcaatttca ttgatgattt
    22681 ggaataaatc caagctgtca gcttctaagt cttcttggat gtcagtagtc aatttgattt
    22741 cttcagtttc ttttcctaat tcttctgcga tgatttcttg aattttttcg aataccataa
    22801 taatatattc ctccgatatt gtttgctttt tatttttata atttaacagt ctacaactcc
    22861 atgagaatac ttccccatgt taaacctccg ccatagcctg taaatattac tttctgctgt
    22921 tttcctaagg tgatctttcc actagaaact gcttcatcca ataagatagg gatgcttgca
    22981 gcagatgtat tcccatattt atccatattg gtcaggaact tttcttgcgg catctttact
    23041 tttcgggcaa ttttctcaat aattctgagg tttgcctgat gcaaaagcag ataatcaact
    23101 ggtttgtctt tcatgacttc ttggatattg tttgcaacgt ctcgtacggc aaaatcaaaa
    23161 atatctctgc cagtcatttg caaataatac gaaccttctg aatcttctga atagaacgga
    23221 tttttatttt gctggtagcc agcggtcaat gagctacttc tggtaccgtc agctgctaat
    23281 ttttctttca gcaatttttt ctgtggattc gcttctaaga gaatcccacc tgctccatcg
    23341 ccaaacaaca cagcagtcgt acgatcagac caatcgatta gcttagatag tgtttcacca
    23401 ccaatcacca gtcccttagt tgagccgcag cggatcattt tttcagccat gcttaacgca
    23461 taaacaaatc ctgagcacgc agcactgata tcaaaagcga tagcatgagt tgctcccaat
    23521 ttcccttgta cttgtgctgc tacagatggt gtcgtgtaat cgggcgacat tgttgctact
    23581 aaaataaaat ccaaatcttt agggtttaga tttttctgtt ttatcaattt ttccgccact
    23641 aaaatgcata aatcagaagt ctcctgattt gttacacatc ttcgttcacg aatacccgtc
    23701 cttgacgaaa tccattcatc agaggtatcc atcatcttgg aaagatcatt attagtaata
    23761 atcttttcag gaaggacgct ggctgttgca gtaatcattc caaattgttc cattaaatat
    23821 cctcacttat agtcttgcaa gaagtcgtgc aagtttttca gtgcatccag caaggcatgc
    23881 tgttcctccg tagccattcc gtctaagatg ttcttgacca tttcacgatg aaaatgctga
    23941 tggacccgaa atagtaactt tccttttttc gttagtccca actttacaac gcggcggtca
    24001 tcttcactgc ggatacgttc gacatagcct ttttttacta acttgttaat agcagtggtc
    24061 aaggtcccaa cagtaattga tagttctttg gctacttctg aagttgtttt tttcttgtac
    24121 atcccgattg cctcgatcgt gtgcatctct gtgattgaca gatctttgaa ttgagatttt
    24181 ttcagctcag actcttcgat tgtcaaaata tcattgaaga cactaacaag ataatcattt
    24241 actgttttta aatctggttc catgttccac cgtccactaa ttagtttgat tatcaaatct
    24301 tttgatgttc aaactatatc ttaacttttt tcaaaatgca accttaaaag atcatttttt
    24361 tactatatga gcttttttta agattttact catttaaaac aactgataaa tcagcattta
    24421 taatttcttt tatta
//
LOCUS       DAJSMK010000033        23829 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.033, whole genome shotgun sequence.
ACCESSION   DAJSMK010000033 DAJSMK010000000
VERSION     DAJSMK010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.033"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(53..787)
                     /locus_tag="ON488_001355"
     CDS             complement(53..787)
                     /locus_tag="ON488_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HCR3231556.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="ON488_001356"
     CDS             1114..1524
                     /locus_tag="ON488_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HCR3231557.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="ON488_001357"
     CDS             1517..2218
                     /locus_tag="ON488_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HCR3231558.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="ON488_001358"
     CDS             2218..3804
                     /locus_tag="ON488_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231559.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="ON488_001359"
     CDS             3823..4044
                     /locus_tag="ON488_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HCR3231560.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="ON488_001360"
     CDS             4041..4802
                     /locus_tag="ON488_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HCR3231561.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="ON488_001361"
     CDS             5182..5691
                     /locus_tag="ON488_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HCR3231562.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="ON488_001362"
     CDS             complement(5766..6305)
                     /locus_tag="ON488_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HCR3231563.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ON488_001363"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="ON488_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HCR3231564.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7318..8169
                     /locus_tag="ON488_001364"
     CDS             7318..8169
                     /locus_tag="ON488_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HCR3231565.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8197..8832
                     /locus_tag="ON488_001365"
     CDS             8197..8832
                     /locus_tag="ON488_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HCR3231566.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="ON488_001366"
     CDS             8852..9625
                     /locus_tag="ON488_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3231567.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="ON488_001367"
     CDS             10033..10830
                     /locus_tag="ON488_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HCR3231568.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="ON488_001368"
     CDS             10808..11221
                     /locus_tag="ON488_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HCR3231569.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="ON488_001369"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="ON488_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HCR3231570.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="ON488_001370"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="ON488_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HCR3231571.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /gene="maf"
                     /locus_tag="ON488_001371"
     CDS             15998..16558
                     /gene="maf"
                     /locus_tag="ON488_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HCR3231572.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ON488_001372"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="ON488_001372"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HCR3231573.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="ON488_001373"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="ON488_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HCR3231574.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="ON488_001374"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="ON488_001374"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HCR3231575.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="ON488_001375"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="ON488_001375"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HCR3231576.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="ON488_001376"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="ON488_001376"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HCR3231577.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="ON488_001377"
     CDS             21905..22483
                     /locus_tag="ON488_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3231578.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="ON488_001378"
     CDS             22535..23017
                     /locus_tag="ON488_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HCR3231579.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="ON488_001379"
     CDS             23134..23508
                     /locus_tag="ON488_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231580.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4285 c         5115 g         6648 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcacccggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atggaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaataa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtttt
//
LOCUS       DAJSMK010000034        23657 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.035, whole genome shotgun sequence.
ACCESSION   DAJSMK010000034 DAJSMK010000000
VERSION     DAJSMK010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.035"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            255..530
                     /locus_tag="ON488_001380"
     CDS             255..530
                     /locus_tag="ON488_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231581.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            543..2621
                     /locus_tag="ON488_001381"
     CDS             543..2621
                     /locus_tag="ON488_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HCR3231582.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2781..4667
                     /locus_tag="ON488_001382"
     CDS             2781..4667
                     /locus_tag="ON488_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCR3231583.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4679..5626
                     /locus_tag="ON488_001383"
     CDS             4679..5626
                     /locus_tag="ON488_001383"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HCR3231584.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5646..6173
                     /locus_tag="ON488_001384"
     CDS             5646..6173
                     /locus_tag="ON488_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCR3231585.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6236..6889)
                     /locus_tag="ON488_001385"
     CDS             complement(6236..6889)
                     /locus_tag="ON488_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HCR3231586.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7021..7863
                     /locus_tag="ON488_001386"
     CDS             7021..7863
                     /locus_tag="ON488_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCR3231587.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8021..8917
                     /locus_tag="ON488_001387"
     CDS             8021..8917
                     /locus_tag="ON488_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HCR3231588.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8920..9633
                     /locus_tag="ON488_001388"
     CDS             8920..9633
                     /locus_tag="ON488_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HCR3231589.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9653..10171
                     /gene="msrA"
                     /locus_tag="ON488_001389"
     CDS             9653..10171
                     /gene="msrA"
                     /locus_tag="ON488_001389"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCR3231590.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10168..10395
                     /locus_tag="ON488_001390"
     CDS             10168..10395
                     /locus_tag="ON488_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HCR3231591.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10547..11098
                     /gene="lepB"
                     /locus_tag="ON488_001391"
     CDS             10547..11098
                     /gene="lepB"
                     /locus_tag="ON488_001391"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCR3231592.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11181..11681)
                     /locus_tag="ON488_001392"
     CDS             complement(11181..11681)
                     /locus_tag="ON488_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HCR3231593.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11960..12358)
                     /locus_tag="ON488_001393"
     CDS             complement(11960..12358)
                     /locus_tag="ON488_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3231594.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12618..13478
                     /gene="ylqF"
                     /locus_tag="ON488_001394"
     CDS             12618..13478
                     /gene="ylqF"
                     /locus_tag="ON488_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HCR3231595.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13471..14238
                     /locus_tag="ON488_001395"
     CDS             13471..14238
                     /locus_tag="ON488_001395"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HCR3231596.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14294..15151
                     /gene="dprA"
                     /locus_tag="ON488_001396"
     CDS             14294..15151
                     /gene="dprA"
                     /locus_tag="ON488_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HCR3231597.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15273..17351
                     /gene="topA"
                     /locus_tag="ON488_001397"
     CDS             15273..17351
                     /gene="topA"
                     /locus_tag="ON488_001397"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HCR3231598.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17320..18696
                     /gene="trmFO"
                     /locus_tag="ON488_001398"
     CDS             17320..18696
                     /gene="trmFO"
                     /locus_tag="ON488_001398"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HCR3231599.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18894..19799
                     /gene="xerC"
                     /locus_tag="ON488_001399"
     CDS             18894..19799
                     /gene="xerC"
                     /locus_tag="ON488_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HCR3231600.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19836..20384
                     /gene="hslV"
                     /locus_tag="ON488_001400"
     CDS             19836..20384
                     /gene="hslV"
                     /locus_tag="ON488_001400"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HCR3231601.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20398..21798
                     /gene="hslU"
                     /locus_tag="ON488_001401"
     CDS             20398..21798
                     /gene="hslU"
                     /locus_tag="ON488_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HCR3231602.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21816..22607
                     /gene="codY"
                     /locus_tag="ON488_001402"
     CDS             21816..22607
                     /gene="codY"
                     /locus_tag="ON488_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HCR3231603.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22689..23564
                     /locus_tag="ON488_001403"
     CDS             22689..23564
                     /locus_tag="ON488_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HCR3231604.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8192 a         4079 c         4983 g         6403 t
ORIGIN      
        1 tttgtcgcag ccccattttt ttgttgtgat aaaagaacaa gaaaggcagg aatgggaaag
       61 taaacatcct tttgtcagaa acttttatct ttcttaagtt ttacttgata tctgatacta
      121 tttggaatag aatgaggcgt tgaaaaattt atggaaattt ctaactagca ataaacgatg
      181 aaacaatgaa atatttttca tccaaaaaga actttgctat aatgatggaa gtttgtgtat
      241 aggagatctg gaaaatgaga gagagttttg aacaacaaaa aaaactgttg catgatcgct
      301 atggcgccct ttcgatggat gaccgccgtc aaatactttg taagttgcgt aaaagaaata
      361 tattgatgta tcgtcagttg gaacgtctga aacatgatct gcttcgtttg gagtcaaaac
      421 gtgtacagtg tgaattagag gggaaccaaa cacaggttga agtagtcgaa accaaaattt
      481 taaagaaaaa agaacaattt ttaaaaatgc ttacacaaaa taaaaaataa aggggatgga
      541 cgatggaatt tgctgagtta gttattgtat ttgcagtaac gatcacctta tcgaacatag
      601 ctagccgcat tttgccaatg attccagctc cactgatcca aattttcctt ggagtggtat
      661 taggtctgac agagtgggga caatcaatcg attttgaacc tgaattgttc ttagttatga
      721 ttattgcacc attgttattt agagaaggag aaaaagcaga tatttcttcg attctcaaaa
      781 atttcgggac aattttgttc ttggcatttg gaggagtcat tttgaccctt gtcggggtag
      841 gtgcgacgtt atcattcctg ttgccaagtg tcccacttgc tgcctgcttt gcttttggag
      901 cagcgttagg tccgacagat gcggtagcag tcagttctct ttctggacga gtgaatatcc
      961 ctaaaaaggc gatgcatatt ttggaaggag aaggtctttt gaatgatgca tctggtgtta
     1021 ctgccttcca gtttgctctt ggtgcgctga tcaccggatc tttttcagca gtaaacgcgg
     1081 ggatgagtct agtagtttct agtattgggg gagctttgat cggctttttg cttgtctggt
     1141 tcaaacaaaa aataattcat ttgatcgaaa aagcatcagc acaagatgtc acagggtatc
     1201 tgctgatcga acttttgctt ccttttctag cctatgtatt ggcagaggca tttgatgtat
     1261 ctggaatcat tgctgcagtg gcagcaggta ttctccaagc ttctggtttt aggaaaatct
     1321 ctgtgtttga tgcagaattg tcgagcttgt cccacagtac atggacaact attgctttta
     1381 cactgaatgc attagtattt atatttttag gaatcgaatt gacgcaagtg ttctcgccag
     1441 tatggggaga cggtttatat ccaaacggtc ttttattagc gattatcgta ttaatctctg
     1501 tcatgctttt tgtgatcaga ttcatttcta tcagtctttt ttatgtattc aaagatggca
     1561 gtaaaaagtt caaaaaacag ttgaacgaga tcttgatctt aacatttggc ggtgtaaagg
     1621 gaacagtcag tttggctacg atttttattt tgccattttc aatcaataat atgatgtttt
     1681 accagcggtc tttgcttttg tttctgacgg cgggtgtcat cttagtgact ttggtcatag
     1741 ggatcattgt cttgcctatg ctgacggaaa cagaggaagc gaaaagcacg gatttgaatg
     1801 ctttgatgat tttagaagag gtcgttgaag ttttgcgaaa agaaataaag gaaattgatc
     1861 gtaatacaaa agaattttta gccactgaag cagtgataga aaattatcaa gaacggatac
     1921 gtgatctgta cttggaagat ttaaccgatg atgaaaagca agaagtacaa gaaatacaag
     1981 cactgatttt gtcgatcgaa cgggatggat tggatgaaag ttatcgttcg ggcaagcttt
     2041 cttctaatgg ttatcgtttt tactcccgtt ttctttctcg attcgaacat tctatcacaa
     2101 gccagatttt gtcttttatc ggcttttggt tcattgttgt ccgtaggtta atgcgaatcg
     2161 ttctccatcc gaaaatgttt tggcaaagaa gatatgctga tcgtcagaca tttattagtg
     2221 atgaagatat ccaagaaatc agagagacat atcaaaaaaa tactcagttg attattgaaa
     2281 gtttagataa cttgactgat atttatgatg aaacgatggt tcaatttttt atccagcaac
     2341 gcaaacttga aggaataaaa atgaactcgg ggaatttgat ttcttcgtgg atgatccagc
     2401 aagatagtct gtttacgaaa aaaatgctaa gaggttatta tcttgaaaga aaaatcattg
     2461 atgaatacga agttgctgaa aaaatcacga cgttttctgc gaacagctat cgcaggaata
     2521 tcaatttgtt agaatcttat acgatgaaca aaccatctga taacttttct ttccgatttg
     2581 cgtttcgagc aaagtcaaaa aaaacgagtc caataaaata aaaaggtaaa aattttcaag
     2641 ttttataaaa aacaaaacat atcagaacag gatcgaatcg gtcctgttct ttttttgaga
     2701 acacaaaaag aacaaatacc aaaaaaattt tcctgaagtt cactattttt atgatacaat
     2761 atccaagata aggagggaac atgttgaaag aattaaaagt aactgacctc aaaaaaactt
     2821 atggtgaaaa agatttgttt gaccagattt cttttttggt ccacgaaaaa gaccgtatcg
     2881 ggttgattgg gacgaacggg acgggtaaaa caagtctctt aaatattatt gccggtatcg
     2941 atagcagcga cggtgatcgg caaacagtgt tttatccaac tgattaccgt attggttatc
     3001 tttctcaagc agctgaattt tccgatgaat taactgttct ccaagcagtc tttcaaggaa
     3061 acagcccctt gatccaaact gttcgagcat atgaggaagc attgatcgaa ctaggggaaa
     3121 acggagaaga ccctgatgtg caaaaacgtt atgctaaagc agaagaacaa atgaataaag
     3181 aagatgcttg gactacagat accaacgcaa agattatttt gcaaaaatta ggaatcagtg
     3241 aattagataa aaaaatcagt actttatcag gtggtcagaa aaaacgagtt agtctggcgc
     3301 aagtgttgat tgatgaaccc gatttactat tactagacga accaacaaac catttagatt
     3361 atgaagcgat cgagtggttg gaaaactatt tgaaacaata ccgtggcgca ctattgatgg
     3421 ttacccacga tcgttatttt ctagatagag tagcaaaccg aatcttcgaa ctttcatttg
     3481 gaaaattata cgagtataaa ggaaattatg aagcttacgt cttagaaaaa gcagaacgtg
     3541 atcgtgtaga agtagaacaa gaagaaaagc gcaagcggct ttataaacag gaattagctt
     3601 ggatgagggc tggcgtacag gcacgtggca ccaagcagca agcacggatc aaccgtttcg
     3661 aagatctaaa ggagaacttg taccaagtaa accaagaaga tgatttagag ctgaacctag
     3721 cgacacaacg tttagggaaa aaagtactgg aaatcaaaga tggcagttac cgtataaatg
     3781 accaaacact gctagaacat ttagatttat tgattcaatc tcgggaaaga ctaggtatta
     3841 ctggtaaaaa tggtgcggga aaatcgacat tgcttaatat tctagctggc agaattcccc
     3901 tggatagcgg tacaatgtct atcggtgaaa cggttcatct tgcgtattat acacaagaaa
     3961 atgaagaaat ggcaccagat aaacggatga ttgcttactt acaagaagct gctgaagaag
     4021 caaaaacagc agatggcagt caaatcggag tagcagaatt acttgaacga tttttatttc
     4081 caagatttat gcatgggaca ctgataggca aactttcagg cggagaaaaa cgccggttat
     4141 ttttgttgaa actgctgatt cagcaaccta atgttttatt attggatgaa ccgaccaatg
     4201 atttggacat agcaacattg acgattttgg aagattattt tagaagtttt ccaggtgctg
     4261 tgatcactgt ttcccatgac cgttatttct tggacaaggt agcagataag ttattagtat
     4321 tccaaggaaa cggaaaacaa gaactttatt acggaaacat gtccagttat ttactgaagc
     4381 aaaaagagac ccagcagcct gctgaaaaag cgaaaccaaa aatacagagc aaggaacctg
     4441 ctgaaaagaa gaaattatct tacatggaac aaaaagaatg ggaaacgatt gaagatgaga
     4501 ttgcagaact tgaagaaaaa atctcattgc tccaagaaga gatgaatcat caaggagata
     4561 atttcactcg attacaagaa ttgcaaaacg acgtatctga aacagaagca caacttgaag
     4621 aaaaaatggc acggtgggaa tacttgagtg aatgggtaga agattaggag gaaaaaggat
     4681 ggaacaagcg tatcttgact taggaagaaa attgttggaa gaagggcatc gtaaagaaga
     4741 cagaacaggc acaggcacat taagcttatt cggataccaa atgcggtttg atctgcaaaa
     4801 agggtttcct ttgttaacaa cgaaacgagt accttttgga ttgatcaaaa gcgaattgct
     4861 ttggttttta aaaggagata cgaatatccg ctatctatta caaaataaaa accatatttg
     4921 ggatgaatgg gcatttgaac gctacatcaa aagtccagac tataatggac cagatatgac
     4981 tgattttggc catagatgtt tgacagatcc tgaattcaat gaagaatata aaaagcagag
     5041 caagcttttt tgcgagaaga tcctaaccga tgattccttt gctgaaacat acggcgatct
     5101 tggacacatc tacggctatc aatggcgtca ctgggaaaca aaagacggtg gctttatcga
     5161 tcaaatcaaa caagtgatcg aagcaatcaa aaagactcct gattctagaa gattgatcgt
     5221 ttctgcatgg aatccggaag atgttcctag catggctttg cctccttgtc atacgatgtt
     5281 tcaattttat gttcaagagg gacggctaag ctgccaattg tatcaacgca gtggggatgt
     5341 gtttctaggc gttccgttca acattgcaag ttatgcgttg ctgactcacc taattgcaca
     5401 tgaaacaggt ttagcggttg gcgaatttgt tcacacatta ggagatgctc atctttatat
     5461 caatcatatc gaacaaatga aagaacaatt gagccgagaa atacgcgcat ttccgacttt
     5521 agttttgaat caggaaaagc agtcagtatt tgattttgag atggaagata tccaattaga
     5581 aggatatgac ccacatccgg cgatcaaagc tcctatcgct gtttagaatc agaaaggatg
     5641 agaaaatgtt agctgcaatt tgggcacagg atgaaaacgg attgattgga aaagaagacc
     5701 gtcttccttg gcgtttgcca aatgatctga aattcttcaa acaaatgaca gaagcaaata
     5761 cactagtgat gggacgaaaa acattcgaag ggatgggtag ccgtccgttg ccgaatcgtc
     5821 agacgattgt tttgacgaga gattcttcct ataaagcaga aggcgtgcat gtcatgcata
     5881 gtgtggaaga cgtgcttgct ctggaaaaag aaacagacgg tatctttttc atcgctggag
     5941 ggtcagctgt ttatcaagaa tttctgccat tttgtacgat attataccgt acagtcatcc
     6001 atcatgtatt cgatggagat gcttattttc cacctgttga ctggtctgat tggtcactga
     6061 tcaatactag tcaaggagaa atggatgaaa aaaatcgtta tccgcatcaa tttgaaacgt
     6121 atcagcgtaa tgagaatcct gtaaaaagcg ggacaggcga attgacgata taaaaaagct
     6181 atggatagac tagctgttat ttagagctgt cccatccata gctttatttt ttttattaag
     6241 taaagaataa aacagagaag tacataaaac ctgcacctaa cataacaaac aaatgccaaa
     6301 caacatgcat atagcggata gaattcaagc tataaaagaa tgcgcctatc gtgtaagaaa
     6361 gcccgcctgc taccatcaaa ataacaccag tcattccaag agagtgataa agaggaacag
     6421 cagccacgac acagagccac cccataaaaa tatagatgat cgtagatact tttgatactc
     6481 tctcccgttt atgcaacgtc aacgctttat atataatgcc aagaatcgca aacaaccaga
     6541 ttaatacaaa taaagtccaa cctagccatc ctcggatact cagcaaacaa aaaggagtat
     6601 aacttcctgc aatcaaaaga aaaatcgaac tatgatcgaa tacttggaac accttttttg
     6661 cttttgtaaa aatcaatgaa tgaaacaaag tagacgttaa aaataaaaga atcatcatcg
     6721 atccatagat agcataagag acaatatgga gggaggaatg caagtgggca ccttttacta
     6781 aaagaaccac tagtcccgcg atactcaatc cagtcccaat tccatgggtg actgcattaa
     6841 acacttcatt taatatttca tacgttcgat taaatttcgt tttttccatg aaaacggctc
     6901 ctttactagg tgtaattaat gaaaaatcat tatttgtctg ttatactaaa aatagaaatt
     6961 gtcttacatg tagtttaaca tgaataaggc atcttgttaa agaaagagag agagaaaata
     7021 atgacaaatg taaaaatcgt aacagattct tcatgtacga tggaaaaaaa tgtacgcgat
     7081 gctttaggca ttcgtgtcat gccgctatcc atcatgatcg acggaacagt atatcccgat
     7141 gatgaccaac tagacggcga aagatttatg gaaatgatgg cgaaagcaaa aaatctgccc
     7201 aaaacaagcc aaccaccaat tggagaattc atctcgatgt atgatgagct aggagaagac
     7261 ggcagtgaag tgatttcgat ccatatgaca aaaggcttga gtggaacagt agaagcagca
     7321 agacaagcca gtaatctaac aaaaacgaaa gtaacggtta tcgacagtga taccactgac
     7381 caaggattat cttttcaggt aattcgagca gctgaattag caaaagaagg taaaacagta
     7441 gagaaaatcc ttgaagaagt caaaaaagta caagacaata caaaattata catcggaata
     7501 tccacactag ataacttggt aaaaggtgga agaatcagcc gaacaactgg tttgctgtct
     7561 agtgttttga acatacgcgt ggtgatgaat ttcgcccatt ctgaattaat ccctgtaact
     7621 aaggggcgag gaaagaaaac gttcgataaa tggtttaata atttgaaaaa tgaactgaaa
     7681 gaattgccaa atgtgcgaca aatcggtatt tcacatgcgg atgcaaaaga attggcgcaa
     7741 gaattcaaag agggtttgca agaattattc ccggacatgc atatccctgt actgcatacg
     7801 aatccggtta tcgctacgca tactggtaaa gacgcgtttg caatcatgta ttatgtagat
     7861 tagtcgaaaa gaggataagc cctcagcctg aaaggcttgc agcttattct ctttttcttt
     7921 ataaaattag gaaaataatt gttttctttt ttcataaaga ctaccttttt gataaaattt
     7981 ttgataacat tagaaccaat cgaatacaag aggtgaaaaa atgaaattaa cgaaacgaca
     8041 tttgatcctc gttttgttcc cattattaat tgcgatcatc atctatgcag gtttagctgc
     8101 ttctataccg aaagctggcc cactaatgaa accagtaact actgtgagag aagatccaaa
     8161 taaaaaagaa aaacttcact acatagctat cggagattcg ctgactgaag gagtaggaga
     8221 tcaaaccaag caaggaggat tcgttcccct tgtcgcaaat gatctaaaag accgttataa
     8281 tttgaccgcg gttgaaacag aaaactatgg tgtaaatggt gaacgaagtg accagatctt
     8341 aaagcgagta aaaacaaaag aagaaattcg aaacaatatc aaaacagctg attttatcac
     8401 actgactgtt ggcggtaatg atttgatgaa agttatccaa aataatttat tcgggttaac
     8461 ggtcaattcc tttaaaaagc cactgaaaaa ctatcaggaa aatgtcacag aactattgga
     8521 agaatttcga tccctcaata aaaccgcacc tatttacatt ttaggcatct acaatccatt
     8581 ttatttgaac tttcctgaga tcactgacat gcagacaatt gttaacaatt ggaacaaagg
     8641 aacagaaacg gtgacaaaaa aaatgccgaa ctgctacttt atcccaatca atgatttgct
     8701 ttatcaagga ttgaatcagg aagtaggtgt cacagaagaa ggaacagatc aaacaactag
     8761 cacgacagaa aatctaaatg gcatcaaaaa taatgtgctc tatgaagaag atcatttcca
     8821 tccaaataat ttaggttatc aattgatggc aaatgcagtg agagatcagc tgatcgagac
     8881 acaaaaccaa tggttagaga aggaggatga tcaataaaca tgaaaacaag atctgacgta
     8941 tcttcaaaca aaacaaagaa aacaaattac tggaaattcg ccttccttat ccttcttggg
     9001 gtagtacttg gttcgaccgt atttttaggc agccgtattt ttgctaatcg ggaaccagaa
     9061 ctcccagaaa taccagctct tacggaaaga caaggagatc ctgtcttaac gatcaattca
     9121 aataaagaaa aagtcaatca aatcatcagc tttttcctta gtgagtatca aaaagatagt
     9181 gatattgaat ataaatttta tttggaaaat gaagcactac tcaatggtac tttcgaagta
     9241 ctaggttttc ctatcgattt ctatttatat tttgatccgt atgtgatgga aaacggaaat
     9301 gtccaactaa aagctagaag tctttctatc ggaacattga gtttgccaat caaagatgtg
     9361 atgaatatga tcaagagaaa ctataaatta ccagattgga tcgaagtcaa tacagatgat
     9421 ctgactatca tgcttaggtt ggatcaattc cgaatgcaaa acgggatgta tattaaagca
     9481 gataaaatcg acttagtaaa tgatgacatt cggtttagtc tatatttgcc aaaagatacc
     9541 tctgatgctt caaacaactc aaataccaac aaaactagca ccagcagtac tgaaagcaag
     9601 acaaaagaaa ataaaaaatc atcggatgag tagtattaga gggggaatca taatggaacg
     9661 agcaatattt gcaggaggct gcttctggtg tatgatccag cctttcgaca cgcttcctgg
     9721 tatccataca gtgatgtcag gatatactgg agggcatgta ccagatccga cttatgaaca
     9781 agtaaaaagc caaacgactg gacatacaga agcagtggag attatctatg atccaacatt
     9841 gatttcatat gaacaattag tagaacttta ctggcagcaa actgatccaa ctgacgcttt
     9901 cggacaattc gaggatcgcg gtgacaatta tcgcccggtg atcttttatt tgacagaaga
     9961 acagcggatc attgctgaaa aaagtaagaa acagttagct gaaagtggac gtttcgaaca
    10021 gccaatcgtt acaaaaatcg aaccagccca accattttat ctagcagaag aagaccatca
    10081 agagtattat aaaaagcatc ctgaaaattt taaaagaaac catgcacgcc gggctgcctt
    10141 tatcgaagaa aattggagga acgaagggtg aatcgaagct tttttcatta tttaatgaca
    10201 ctgcgaggcg gtggcacaca tgatgcttta tctgttttcg ctacagaagc cggtaaagac
    10261 atccaatttc ctaagcacag ctctagctac gaagaaattt ctaattatct ggaactgaat
    10321 gtcgactatt tgccgtccat ggatatcttt gacgaagcat gggaaaaata tttagaaaat
    10381 aatcatgaca tataagagat agttttgtac tttatgatca aaaaagtttt ttgtccaata
    10441 gcctaattga aagaattatt tttatttcag ctatctagtc gcattttttt gatatttttc
    10501 ttataataaa gaaagaatga aaaaaagagg gatggattga tagagattga caaaaaaaca
    10561 acgctatatt aatcgcttct ggcttgtatt caaatactta cttgtttctg tattccttgc
    10621 gttcatgttg cggggatttt tattcatccc ggtaccagtg gaaggcaatt caatggaaaa
    10681 cgtgttgaag caaggtgata tggttgtgat ggaaaaattt tcggagatca gacgatttga
    10741 tattgttgtt tttcaattag cagatggcac gatttatatc aaacgagtaa tcggtcttcc
    10801 aggagaaaat gtcagctacc aaaatgatca attgaagatc aatgggaaag tagttaagga
    10861 accttatcta actaaaaacc tgaaatcaga tcatgcaaat gcatcctata cgacggactt
    10921 tacactacaa gagctaacgg gacaatccaa gcttccggaa gataattatt ttgtacttgg
    10981 agataatcga agagtttcaa aagatagtcg ttcgtttggc acgatcaata aaactgatat
    11041 tctaggtaaa gcaagatttg tctattatcc acttgatgaa ataaaatgga tccagtgaga
    11101 aacaataaag cgtgcagtct gttgagactg cacgctttat tgtttaatcc aaaatcagtt
    11161 tactacctta gtacgtaaaa tcaaacagct cgtttaaaca cttttctagc ctctaaagtt
    11221 ttgataaatg aataaacaac cattatttga atagggattt ggatcatatt cctgatgaat
    11281 ctacctagaa aaattacttt gaaatctgca ccaaacaaaa cagacatcag ccaagaattg
    11341 ataaaaaggc tgactgggat cataatcaat aattgggcag cgatgacgga aggcaggttt
    11401 atctttttat gatataaaaa taagccatta ataaatccac caaggaaagc cgtgataaga
    11461 aaagcagctt gaaacgttcc tgaaccaaat atcgtgaaat ttaaagtgtt cgacaacatt
    11521 tcaagcaaac cagcccagat cggtccatat agataaccca taagcgccat acttaaaaat
    11581 ccgaatgtga tttgaaaata agcaggacca atcgctatct tgtataagat gacatcaagg
    11641 gctaataaaa gagcagaggt cgacaacaat cttgcattca tttcgggcaa tctaaaaacg
    11701 tcttttgcaa tcaaagtgtt caaaatattc tctcctttgt cagttaataa taaaaggata
    11761 ccataaaatc accaatgtgt catgacacat tggtgattta catacactgg catctaacaa
    11821 ttaaaaaaag ggtgagaaga ctgcttttat aaactgtaaa aaagagattg tacgaataaa
    11881 aaaaatagag gcggagaata cttatcgtat catccgcctt tgtttttttg ttataaaaaa
    11941 cgtcagatta gttatctgct tacatcttca tccatacggg ttctaatgta tttccgtcta
    12001 gatcttggac ttctaatgaa aacatttctt cttcaggcat tcccatatct acttcgtgga
    12061 aagtaccacc attttctttt gcaatttgag caaatttttt tacttcatcc gcattttcaa
    12121 cactaaacga aatcaaagca ccacttgttt ttttattatc agctatttct ttatctttta
    12181 taaatttttt ataaaaatca tgagagagaa gcattatcca aaaagtgtca tcccatacca
    12241 ttgaaccagc ttcttcagta gaaaattctt catttttttt aaaacccagc ttttcataaa
    12301 aagcaacgga acgattgaca tcagcaacag gaaaattaac aaaaaccata ctattcattt
    12361 gtttcgtctc ctttctgttt tgttcgtcta tcatctctta tttaggaaac gctgtcaaaa
    12421 atttagattc atatatagaa accaaaataa aaatttgcat catcaaaaaa gtgaagatgt
    12481 gatagaatga ggactggttc actttcactt aactaataga tggaatttct ttataataaa
    12541 aaagtgaatt tatattgaaa aagaaaaaaa caagtaaagc cggggaatat tccggtatga
    12601 aaggaatgga gagaacaatg accatccaat ggtttccggg acatatggca aaagcccgac
    12661 gagaagtttc tgaaaaaatg aaatatgtgg acatcgtatt tgaattggta gacgcacgat
    12721 tacctttatc ttctcgtaat ccaatgctag atcagatcat tcagcaaaaa cctcgccttg
    12781 ttttattgaa taaagcggat ctggcagatc cacaacagac aaagctgtgg caagaatatt
    12841 ttcgtaaaca aggccatctt gcattagcta tcacggcaca agaaagtaaa ggaattaaag
    12901 gtctagtacc tgcggctaaa gaagcattga aagaaaaacg ggcaagagat gctgctcggg
    12961 ggatcaagcc tcgcgctatt cgggcaatgg tcttaggtat tccaaatgtt gggaaatcta
    13021 cgttgatgaa tcgactagta ggcaagaaaa ttgcacagac aggaaataag cctggcgtaa
    13081 caaaaggtca gcagtggctt cgtttaggta atgagttgga attgttagac acaccaggga
    13141 ttttatggcc caaatttgaa gatgaagaaa tcggcaaaaa actagcgctg acaggcgcga
    13201 tcaaagacca gcttgtccat ttagatgatt tagcgattta cggattagac ttttttgccc
    13261 gatattattc aggaagaatc agcgatcgtt atggtttatc aatcgagcaa gaagaaaaat
    13321 tggcaccgga attactgatg gatattacag caaaacgtgg gtataaagaa gactatgatc
    13381 gtggcagcga attagtcgtg catgatattc gtcaaggaaa acttggacga tacacactgg
    13441 atcgttgcga agaaatggag caaaaaagtg atgactgaat ccatccaaag tatcaaagaa
    13501 cgattgaaaa gcatacagag aatagatgat cctacactag aatcattaag aaatgatcca
    13561 cgcaaaggcg tgcagcaagc actggcttct tttgaacgac gattgaaaaa ggaagcatta
    13621 attaaggaaa aatatgaaga aatgttttgc tttgaaaagc aagggtacgc acaaggtcac
    13681 caatggattg ccggcattga tgaagtagga agaggaccat tagctggacc tgtcgtggca
    13741 gctgcagtta tcttgccgaa aaatgagatc atattagggc tgaatgactc caaacaatta
    13801 tcagagaaaa agcgagaact tctttatcaa caagttcaag aaaaagccct ggcaatcggg
    13861 atcgggatcg ttgatcagca gacaatcgat gatgtgaata tttatgaagc aagtaaatta
    13921 gcgatgatcc aagcagtaga aaaattgtcc attgtaccaa gctatttgtt gatcgatgcg
    13981 atgaccttgg atttgcctat tcagcaggaa aaaataatca aaggggatgc acgatctgtg
    14041 tcgattgctg ctgcaagtat cattgctaaa gtatatcgag accaattgat gaaagaatat
    14101 gacgtgcttt atcctggata tggtttctcg cataatgcag gttatggaac aaaggaacac
    14161 ttagaaggac ttgaacgaca aggaattacg ccaatccatc gtaaaagttt tgcacctgta
    14221 aaaaaatatt tacaataaaa aacagccgct tttacgtatc ttattagaaa gagagacgaa
    14281 aggcggtttt atgatgtatc aaatagaaga aaatttattg aaacttgctt atacaaaagg
    14341 aatcagtagt caaggaaaat gggcacttgc taactggatg atgcagtatc cttataaaga
    14401 aatcggattt gaagacatca ttaagatagg taaaataacc aaacaccggg agctgtttcg
    14461 caaaagttgg caggaaattc acgctaactg gggcaaaatc caatcgaaac agtcgtttat
    14521 cacttgcttt gatcccaaat atccccctca gctgcttcac ttgacctatc cgccaattgt
    14581 actgttttat aatggtgatc tatctttact ttcttgtaac atgttaagcg ttgttggtgg
    14641 aagacacact tctgctttag ccaaaaaaac agtttattat ttactaaaac cagtgataga
    14701 agctggatat gtgatcgtca gtggctgcgc gaaagggata gatacatacg gtcaccaagc
    14761 agcaatctct catggtggac ggacaatcgc agtcattgga acagggatag agcaagtcta
    14821 tcctgctgaa aatcgtgact tgcaagaggt gattgcaaat gatcatcttc ttttgagtga
    14881 atatcctcct caatccggcc cgaaaaagca ttgttttcca atgagaaatc ggattatcgc
    14941 agctttgtct aaaggaacat gtgtctttga agccaagaaa aaaagcggct ctctgataac
    15001 agcacagcaa gcattggatc ttggaagaac agttttttct gttccaggaa atattttaac
    15061 agaacattct accggatgtc atcatttgat ccaagacggt gcagtttgca cggtttcggg
    15121 tgaagatatc ttggcagaat ttaaagaata acaccatact tttcatttgc ttttcttgac
    15181 aaacgttttc tgaatggata tgattagcta cgatttgtat gaatcctctt ttaatagtag
    15241 gaacacgaca atggaaagga gtccattcag taatggcgta taaatattta gtgattgtag
    15301 aatcacctgc aaaagccaag acaattgaga aatatcttgg acgaaactat aaagtaatgg
    15361 ccagtgttgg ccatataaga gatttaccga aaagtaaaat gggtatcgat tttgaaaaca
    15421 attatgaacc ccattatatt tctatacgcg gaaaaggcga tgtcatcaaa agcctgaaag
    15481 ccgcagcaaa aaaagctcaa aaagtttact tggcaagtga cccggataga gaaggagaag
    15541 cgattgcttg gcatttagcg tacctacttg ggttggatct gaaagaaaaa aatcgggtgg
    15601 tcttcaatga aatcacaaaa gacgcagtca aagcagcttt taaggaacca agaacgatcg
    15661 atgtagattt agtagatgca cagcaagctc gtcgtacctt agacagaatc gttggttatt
    15721 cgatcagtcc tattctctgg cgtaaggtca agaaagggtt aagtgcagga cgtgtccaat
    15781 ctgtcgcttt aaaaattatt attgaccgtg aaaaagagat ccgagaattt gttccagaag
    15841 aatattggag catcgacggt aattttaaaa aagctcgcaa gaaattcaaa gcaaatttct
    15901 ggggaatcga cggtaagaaa aagaaattac cagatgcaca aagtgtaaaa gaagtcactg
    15961 ctagaattga tggaacagac ttcgaagtta aaaaagtaga aaagaaagag cgcaaaagaa
    16021 accctgcgaa tcctttcact acaagtagcc tgcaacaaga agctgcccgt aagttaaact
    16081 ttcgaacaag aaaaaccatg atggtagcac agcaattata tgaaggaatc actttgggta
    16141 aacaaggaac agtcggcttg attacataca tgcgtactga ttctacccgg attgccgata
    16201 cagcaaaagc agaggccgca gcatttattg aagatacgta tggaaaagaa ttttctagac
    16261 atgatcaccg aaagatcaaa aatgctcaag gcgcacaaga tgcccatgaa gctgtgcgtc
    16321 caacgagtgt gcttcgtaca ccagatgaac tcaaacaata tttagataaa gatcaattga
    16381 aactttatac attgatctgg tcacgttttg tggctagtca gatgacacca gctattttag
    16441 atacaatgaa agtgacatta gaacaaaatg gtgtcatctt cattgcgaac ggttcaaaaa
    16501 tcaaattcaa aggattcatg caagtgtatg tggaaggtag agatgacggc aaagaagaga
    16561 aagaaaatat tcttccagaa cttgaagaag gcgatgtagt ccaatctgtt gatattgaac
    16621 caaaacaaca ttttactcaa ccaccagcac gttttagtga ggctacgttg attcgtgcac
    16681 tagaagaaaa cggggtaggg cgaccttcca cttatgcacc aacacttgat acgatccaaa
    16741 gacgctacta tgtaaaattg acacaaaaaa gatttgagcc gactgaacta ggagaaattg
    16801 tcaattcatt aatctgtgaa ttcttccctc aaatcgtcga tatccatttc acagcagaaa
    16861 tggaaggaga tttggataaa attgaagaag gcacggaagc gtgggtcaaa gtggttgatc
    16921 gtttctataa accgtttgaa aaagaactga cgaatgcgga agaaaaaatc gaaaaaattc
    16981 aaatcaaaga tgaaccagca ggattcgatt gtgatgtctg tggacatccg atggtgataa
    17041 aattagggaa atatgggaag ttttatgctt gcagtaattt tcctgattgt cggaatacga
    17101 aaccaatcgt aaaagaaatc ggtgtgactt gcccagtatg tcatgaagga caagtcattg
    17161 aacgaaaatc taagaaaaac agactattct atggttgttc ccgtttccca gaatgtgaat
    17221 tcacttcttg ggataaacca gtgggcagaa attgtccaaa atgtgacgga tatctggtcg
    17281 agaagaaagt caaaggcggt aaacaagtag tctgtgtaaa tggagattac gaagaagaca
    17341 tccaaaaata atagaaaaga ggttctttca ttgaaaatgg taaatgttgt tggagcaggg
    17401 cttgccggaa gtgaagctgc ttggcagatc gcacaagcag gagtccctgt ccgtttatat
    17461 gaaatgcgtc cagtcaaatc gactgaggcg catcacacaa gtaattttgc tgaactagta
    17521 tgttccaatt cattaagagg aaacagtttg gctaatgcag tagggttatt gaaagaagaa
    17581 atgcgccgat tgaattcggt agtaatcact tcggcagatg aaacagcagt gccagctggt
    17641 ggtgccttag ctgttgaccg cgattctttt tctgaaacaa ttacccgaaa agtcaaagag
    17701 catccattag taacagtgat aaacgaagaa attactgaaa taccggaagg aatcaccgta
    17761 gtagcaacag gacctttgac ttctcatcca ttagcagaaa gcatcaaagc attcaatggt
    17821 tcagatggtt tttatttcta tgatgcagct gcaccaatcg tagacaaagc tacgatcgat
    17881 atggataaag tatatttgaa gtcccgctat gacaaaggag aagcagctta cttgaactgt
    17941 ccgatgacag aagaggaatt caaagctttc catgaggcac taatcaatgc cgaagtggca
    18001 gaacttaaat cttttgagaa agaaaaatat tttgaaggat gtatgccaat tgaagtaatg
    18061 gcacagcgag gattcaaaac gatgcttttc ggacctatga aaccagttgg attggaagat
    18121 cctaaaactg gcaaacgtcc ttatgctgtt atccagctgc gtcaagacaa tgctgcagct
    18181 tctttataca acatcgtggg ctttcagact cacttgaaat ggggcgagca aaaacgtgtt
    18241 ttccggatga ttcctgggtt agaaaatgct gaattcgttc gctatggtgt gatgcaccga
    18301 aacagcttta tgaattcgcc agaattgctg aaaccgactt accaatcaac gaaacgcgaa
    18361 gatctgttct ttgcaggtca gatgactggt gtagaaggct atgttgaaag tgcagcgagc
    18421 ggactacttg ctggaatcaa cgccgcacgc ttagcaaaag aaatggaacc agtcgagttt
    18481 ccacaagaaa cagctattgg aagtatggct tactacatta ctcatgcgga aggaaaacat
    18541 ttccaaccga tgaatgccaa ctatggtctg tttcctgaac tgccagagcg cattcgagac
    18601 aaaaaagcaa gatatgaagc aattgcacaa cgagctttaa aagctaatga ggcaataaaa
    18661 acagaattag aaaaaactgc aatcccaaat gagtaaggaa actccatgaa gagggtgaga
    18721 cggatagtct cgctcttttt cttgcgtttt tcttaagaat ttctcaaaca aaatgtgagg
    18781 aattgcgcca attgtgaaca aacttagaaa tattggttaa attctgacaa tttatttgtc
    18841 tttttataaa cgctgtgcta aattattctc tgggacaaaa ggaaggtgag aaaatgacag
    18901 aagccacgtg ggaacaaaaa tttttgcgtt atttgattgt cgaaagagga tattcagaaa
    18961 aaacgaaaga agcatatgaa gaagacattc tccatttcaa acattttttg gaggaatctg
    19021 gagacgctga tctgctgaag gcggaatatt ttacggttcg tgtctatttg agtgcattag
    19081 ctgatcatcg tcctagctat agcagaaatt ctatcagtcg caagatagcc agcctacgtt
    19141 cgttttatca gtatcttctc aaagaagaag tgataaaaga aaatccattt tcttacgttc
    19201 atctcaaaaa gaaaaatttg agactgccac gtttttttta tgaaaatgaa atgcaagcac
    19261 tttttgacag cgtagcagga gatagtcctt tggatttgag gaaccgcgct ttactggaag
    19321 tcctttacgg gtcaggcatc cgtttaagtg agtgtagcag tttgtcggta tcagacattg
    19381 attttgattc agaggtcatg ttgatccatg gtaaagggaa caaagagaga tatgctcctc
    19441 taggttcttt tgctcaagat gctctgcaag aatatttcag ggaaggccgc caggtattga
    19501 tgacaaaata tcacgaagag catgatatcg tttttgtgaa tcatcatgga aaaccaatca
    19561 cgcctactgg aattgaatat gtcttgaatc aaatgatcaa aaaaagcagt ttggatagtg
    19621 atatccatcc tcacatgctg cgccatacat ttgctactca tttattaaat aatggggcag
    19681 atttgcggac agtccaagaa ttgctaggac atgccaattt atcgactacc cagatctatg
    19741 cccatgtaac aaaagaaagt ttacaaaaaa actatcgttc tttccatcca agagcgtaaa
    19801 aataaggaaa agaacaaatt taggaggaaa caaacatggt cgaatcacca tttcattcaa
    19861 ccactatctg tgccgtcgaa aaagacggga aatttgctat ggctggagat ggccaagtaa
    19921 caatgggtga atctgttgtc atgaaaggca ctgcaaagaa agtacgacgt atctacaatg
    19981 gagaagttgt tgtaggtttc gccggaagtg ttgcagatgc gtttacttta gaagaaaaat
    20041 ttgaaggcaa actaaacgaa tataacggga atctacaacg cgcagctgtc gaattagctc
    20101 aagaatggcg gacacagcaa tctatgcaaa aacttgaagc gatgctgatc gtaatgaatg
    20161 ataaagaaat gcttcttgtt tcaggtacag gagaagttat cacaccagat gatggtatct
    20221 tagctatcgg atcaggaggg aattttgcgt tggctgcagc ccgagcaatg aaaaactatg
    20281 ctcaaaacga catgagtgcg aaagaaattg cagaaaatgc gttaaatatt gccgcagata
    20341 tctgtatctt tactaatcat aatattatcg tagaagaact gtaagaggtg agtagatatg
    20401 tatgaattaa aacaaacacc aagacaaatc gtaagtgaat tagatgaata tatcgtagga
    20461 cagcacgcag caaaaaaatc tgttgccgtt gctttgcgta accgctatcg ccgtttgcag
    20521 ttagatgaaa aaatgcaaca agatattaca ccaaaaaata tgctgatgat cggacctaca
    20581 ggggtcggta aaacagaaat cgcacgacgt ttggcaaaaa tcgtcaatgc accatttgtc
    20641 aaagtcgaag caacaaaatt tactgaagtc ggttatgtcg gaagagatgt agaatcaatg
    20701 gttcgggatt tagtagaaaa tgcgatccaa atcgtagaaa aagagcagta cagccgtgta
    20761 tacacaagtg ctaaaaaaaa tgcagaaaaa cgtttggtaa aaatcttggt acctggtatc
    20821 aaaaaagaac agaaacaatc cactaatcaa tttgaacaaa tgatgaatct ttttaatgct
    20881 agtcagcaaa ataccgctga accgcaagaa gaagtgacag aagatattcg aatcaatcgc
    20941 cgtacagtct tggaacaact acaaaagggt ttactggata gtcgtgaagt aaccattgaa
    21001 gttgaagacc aaaagaaacc tgcaccaatg atgaacaatg gattggagca aatggggatc
    21061 gacctaaatg aaactctagg tgctttgaca ccgaagaaaa aagtggaacg gacggtaaca
    21121 gtcaaagaag ctttagagtt attgatcaag gaagaatcag caaaattagt caaggatgct
    21181 gatatccata gtgaggcaat caaattagcg gaagaaagtg gaattatttt tatcgatgaa
    21241 atcgataaga tcacttctaa atcacagcaa tctggagaag tatccagaga aggcgtccaa
    21301 agagacatat tgccaattgt cgaaggttca caagtaaaca caaaatacgg gatcatccaa
    21361 acagatcacg tcctattcat tgcttcagga gctttccatt tgtctaaacc aagtgatcta
    21421 attccagaac ttcaaggacg cttcccgata cgggtagaat tagatgattt gacagctgaa
    21481 gattttgtga agattctgac cgaaccaaat aatgctttag taaaacaata cgtcgcgttg
    21541 atcggtacag aaaatgtgtc agttacgttt acaaaagaag caattgaacg gatcgctcaa
    21601 atcgctttcg atgtcaaccg tgacacagat aatatcggcg cacgcagact gcataccatt
    21661 ttggaaaaac tactagaaga tctattattt gaagcaccag atatgcaaat gggagaaata
    21721 acgatcacag aagcatatgt ggatgacaaa cttggctcaa ttgcggcaaa tgaagattta
    21781 agtcgctata ttttataaaa aatcggagga cgacaatgac agacttgcta acgaaaaccc
    21841 gcaagataaa cacacttttg cagcaaaaga atacttttga catgcaagca gatttgcctt
    21901 acgataaaat ggctgtcaca ctaggtggta ttcttgacag caacacctat atcataggaa
    21961 gtgacggagt attactaggt tataatgaac gtcacgatgt gaacaatgaa cgaatcaaaa
    22021 caatgtttgt tgagaaacaa tttcctgaat cttatactga tacagtggca cagttgatga
    22081 aaactgaagc taatatccca attactagtg atattactgc atttccggta gagtcaagag
    22141 agaaatatcc atttggtctg acgactgtcg ttccgatctt tggagctggc gaacgtttgg
    22201 gtacgattat cttatctcgt atggaacaat cgtttgcaga tgacgatcta gtcttagcag
    22261 aatatggagc tacggttgtc ggtatgcaga tcctttatca gaagtctcga agcatcgaag
    22321 cagatgtacg gagtgcaacg gctgtccaaa tggcaatcaa cacattatct tatagcgaat
    22381 tgaaggctgt acaagctatc tttgaagcat tggatggaga tgaaggtcgt ctgactgctt
    22441 ctaatattgc cgatagtatc ggcatcactc gttctgtgat cgtcaatgct ttacgaaaat
    22501 tggaatcagc tggaatcatt gaatctcgtt cgttaggcat gaagggaact tatttaaaag
    22561 tattgaattc ccgttttaaa gacgagttag caaaacacag ttattagaag taaggggact
    22621 ggggcagata gaaatgtttg ttccagcctt cccattttaa aaagtaagtc gaagttggag
    22681 gaatggcaat gactgttatt attcaaaatg accagctgat cgccgaaatc gctgaacacg
    22741 gtgcggaatt gatcagtctg aaatcaaaag aacatggttt agagtatatc tggcaaggtg
    22801 atccagcgta ttggggcaga catgcaccgg ttttattccc ttttgttgga cgtttaaaag
    22861 atgatcagta tgtttatcaa gggaaaacat atcaaatggg gcaacacgga tttgctcggg
    22921 atatggattt tgaagtcatt gaacatggac aagaaatggc tagtttcatc ttaaggagta
    22981 cgccggagac attagaaaag tatccatttg attttgaatt agtgatcagc tatgaattag
    23041 gaggagacgg catcacggtt cattatcaag tggcaaatac cggtgaaaaa gaaatgttct
    23101 tttctatcgg tggacatcct gctttcaatg tacctcttga agaaggattg tcatttgaag
    23161 atttctatct ggcattttct ccattgaaat caagattacg cctaccattg aaaggcccat
    23221 tcatcgatat ggatcaaaag acgttaggtc agacaaatac gaatctggct ttgaatcgtg
    23281 aactttttga gcaagatgcc ttggtttttg aaacaagggg tctaaatgcg tacgccattc
    23341 gaagtgaaaa atcttcccat agcgtaactt taagctataa agatatgcct tatgtaggga
    23401 tctggtctcc ttatccaaaa gaagcgcctt tcgtttgtat cgaaccgtgg tgcggaatcg
    23461 ctgacacggt gaacagtagt ggaaacttga tggaaaaagt agggatcaat caactaggtg
    23521 cccatgaaat cttcaagaca aaatattcca tcacagtgaa gtaagaggtt gtgaccgaga
    23581 agttagcagg gaacaccgtt taccaaggtg tgtaaaaaag ctatcctgta agtaataagg
    23641 gagtgtgaca tcgattt
//
LOCUS       DAJSMK010000035        23573 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.036, whole genome shotgun sequence.
ACCESSION   DAJSMK010000035 DAJSMK010000000
VERSION     DAJSMK010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.036"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(461..1090)
                     /gene="udk"
                     /locus_tag="ON488_001404"
     CDS             complement(461..1090)
                     /gene="udk"
                     /locus_tag="ON488_001404"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HCR3231605.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1174..1869)
                     /locus_tag="ON488_001405"
     CDS             complement(1174..1869)
                     /locus_tag="ON488_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HCR3231606.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1882..2598)
                     /locus_tag="ON488_001406"
     CDS             complement(1882..2598)
                     /locus_tag="ON488_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HCR3231607.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2928..3533
                     /locus_tag="ON488_001407"
     CDS             2928..3533
                     /locus_tag="ON488_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HCR3231608.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3858..4181
                     /locus_tag="ON488_001408"
     CDS             3858..4181
                     /locus_tag="ON488_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HCR3231609.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4363..5733
                     /locus_tag="ON488_001409"
     CDS             4363..5733
                     /locus_tag="ON488_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HCR3231610.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5863..7164)
                     /locus_tag="ON488_001410"
     CDS             complement(5863..7164)
                     /locus_tag="ON488_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCR3231611.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7394..9352)
                     /locus_tag="ON488_001411"
     CDS             complement(7394..9352)
                     /locus_tag="ON488_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HCR3231612.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9529..9795)
                     /locus_tag="ON488_001412"
     CDS             complement(9529..9795)
                     /locus_tag="ON488_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCR3231613.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="ON488_001413"
     CDS             complement(10305..12431)
                     /gene="pnp"
                     /locus_tag="ON488_001413"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HCR3231614.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="ON488_001414"
     CDS             complement(12619..12888)
                     /gene="rpsO"
                     /locus_tag="ON488_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HCR3231615.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13139..13702
                     /locus_tag="ON488_001415"
     CDS             13139..13702
                     /locus_tag="ON488_001415"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HCR3231616.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13955..14476)
                     /locus_tag="ON488_001416"
     CDS             complement(13955..14476)
                     /locus_tag="ON488_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HCR3231617.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14479..15321)
                     /locus_tag="ON488_001417"
     CDS             complement(14479..15321)
                     /locus_tag="ON488_001417"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HCR3231618.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15314..16039)
                     /locus_tag="ON488_001418"
     CDS             complement(15314..16039)
                     /locus_tag="ON488_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HCR3231619.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16215..16511
                     /locus_tag="ON488_001419"
     CDS             16215..16511
                     /locus_tag="ON488_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231620.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17079..18671
                     /locus_tag="ON488_001420"
     CDS             17079..18671
                     /locus_tag="ON488_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCR3231621.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18684..19424
                     /locus_tag="ON488_001421"
     CDS             18684..19424
                     /locus_tag="ON488_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCR3231622.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19592..20941
                     /locus_tag="ON488_001422"
     CDS             19592..20941
                     /locus_tag="ON488_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3231623.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21069..21659)
                     /locus_tag="ON488_001423"
     CDS             complement(21069..21659)
                     /locus_tag="ON488_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HCR3231624.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21806..23158
                     /gene="brnQ"
                     /locus_tag="ON488_001424"
     CDS             21806..23158
                     /gene="brnQ"
                     /locus_tag="ON488_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCR3231625.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6751 a         4747 c         4490 g         7585 t
ORIGIN      
        1 tagggggtgc gacaaaagag cttcttcaaa aaaataagtc gaaatctcac acaaattcga
       61 gaaataattt tcgtaagttt cttcttattt attgcatctg accacttctg ttacaacctc
      121 tcgttaaacg gtgttcaaaa gcttgcatct acgataataa gcccaaccca acgaaaaacg
      181 tgaggagctg ttttatttgg atgctcttat cgcttgatgc aaagacagct tttttacaac
      241 ctctacttca cggtgctcaa tcagctgacc ttcggtatta gctcaaaaaa cggtaaaata
      301 taaacagcta ttttccgttt cttcttttta atacttaggt caagatgctg ttttcacaac
      361 ctcttgttat aaataaaaaa acagttggct ggtgactgtt caaaaagcag aatccttgct
      421 tttcaaacgg tcgcagtccg ttcaactgtt tcgctgcgca ctatttatgg tttaagaaac
      481 tagctacttt tgttgtaatc aaatcaatag caacgtggtt ttctccgcct tctggaacaa
      541 tgatatccgc atagcgcttc gttggttcga taaattgatg atacatcggt ttaacaactg
      601 tcaaatattg ttcgatcacg gagtccaatg tgcgtccccg ttcttccata tcccgtttga
      661 tacgacgaat gatacgaatg tcatcatctg tatctacgta tactttgata tccatcaagt
      721 cacgcagacg ttcgtcttct aaaatcagga ttccttctag aatgatcact tcttttggtt
      781 cctgaatgat cgttgcctga cttcttgtat gcgctacata gtcatacacg ggtttttcaa
      841 tggctttata gttcagtaag tcgcctacat gctgaatcag cagatcatta tcaaaggcaa
      901 atgggtgatc gtaatttgtg ttcaatcgtt cttcaaaact caaatggctc tgatccttgt
      961 aataagaatc ttgttcaagc atcatgatgg aatggtccgg gaagttgttg aaaatcgcac
     1021 ggctgacact tgtctttccg cttccggatc cacccgtcac accaatgata attggcttgc
     1081 tttttgtcat tgactaaaac ctctttcgta tccgtttttt cattctaatc tattatagcg
     1141 aaaaaacacg aaaatgctat atttttctga aaattaatcc ttttcaattt ccaataatga
     1201 ataaagttcc tctaatgaat cgattcgata agtaggctgg atttcttcga tttctggtaa
     1261 tttatttcta ttgaaccaaa tcgtatcgat ccctgccata tttcctcctt tgatatcaga
     1321 agtcaaagaa tcaccaatga tcacagtttg ctttttatca aaattaggaa tgtgggaaaa
     1381 gacatgatca aaaaattctt tcatcggctt ttgcgctccg acagcttctg agacaaagat
     1441 atccttgaag taatcaagca ttcctgcatc tgttaatcgc cgatgttgcg tgtgcgacac
     1501 accgttcgtc acaatataaa gatcagcatg cggatggacc tttttcagga tttctagact
     1561 tcctggaaca agatcatgac cttggttcaa gtagtggcgg tagcgttttt ccatttgatc
     1621 actatctact gttttcccaa attgctggaa aagtaaccca aaacgactgc ctattatttc
     1681 ttctcgtgat agtctgcctt tttcaaactc ctgccataaa tgatgattca aagccttata
     1741 gctggtttcg atttctggtg tcaatgtgat tccttgttct gcaaacaaag cacttaaagc
     1801 attggcttca gttaattgaa aatctaacaa tgtatcatct acatcgaaca ataaagtttt
     1861 atatttcatc tttttgacct cctatttaaa ataaatactt aactttttca tctctgctaa
     1921 tgtcaacgat cgatactcgc ctactcctag ctgttcatct aattccaatg gtcccatgct
     1981 tagccgtttc aatgcggtca ctttctttcc ttgggctaag aacatctttt tgacttgatg
     2041 gaattttcct tcttggatcg tcaataaaac cgtactttgg tgcttgtctg ctttgagtat
     2101 ttttaaatca gccggcttac attgataccc atcagcgaat acgattccat tttcaaatgc
     2161 tgttacgtct gccggtgtca ccctttcgtt cacaactact tgataagtct ttgaaacctt
     2221 tttttctgga agtagcattt catatcccaa ttgtccattc gaagtgatca gcaatagtcc
     2281 tgttgtatct ctatctagtc ttcccactgg atataatggt tggaaacgat cggcacttgc
     2341 aatcagatcg attactgtcg tcttttctgg atctgataca gctgtaacag ctttttcagg
     2401 tttattgaga agataatagg actcatttgt ttctaagtgt tcacctgcta cttcgatttg
     2461 atgcagtaaa ctatctacat ttcgattttg tcgaaattcg actgtgccat ctatcatcac
     2521 ttgcttcaaa gcaaacagcc gcttcatttc cttgcgtgtc gtttctaatt tttcttctat
     2581 taatttatct aaacgcatgc tgtttccttt cttattacta ctaattaatt ataccttgaa
     2641 tattcttgct tgcaaataca tcatcatagt tattccttga cttaattaac agttcacgtt
     2701 acggttaaat agtaaagtga attggatttc tcatacacag cgtaatgacc tggtggagaa
     2761 aagttgaatc ctgactttct aaggggagat gcgcgcatct ctccttttgc gcttttttaa
     2821 gcgccctgcc ttcgatgatg tgcacgagat tagcctttag aattcactta aataaaatct
     2881 gtccgttacc aaagcagaca gtcacatttt aaggaggaat tttggttatg tcagtatcat
     2941 tagaagtaag taaaagagaa gtacgtcccc gttcattaag aaacaaactt cgtcacgaag
     3001 ggaaagttcc agctgttgtt tatgggtata aagtagaaag tacccctatc tcattcgatg
     3061 gtttgacact aagcaaattg ttgcgtgaac atggagcgaa cacagtcatc acgatggaca
     3121 tcgatggaca aaaagtcaat acattggttc acaagatcca aacgaacact tttaccaatc
     3181 atttcgaaca tgcagaattt ctatctgtaa acatgtcgga agaaacagaa gtcgaaacag
     3241 aagtcgttct tgttggcgaa tcagtgggtg ctaaatctgg tggagtgtta gctcaaaact
     3301 tgtatacagt agtcgtatct gctacaccag acaaattgcc tgaacgaatt gaagttgacg
     3361 tgacaaactt ggaattaggt gattctatta cagtagccga tcttccaaaa aacgacgatt
     3421 acaaattcgt gaccgacagt gaagagcaaa tcgctgctgt agtcgctcaa agtgaagaag
     3481 aaagcacagg tgaaggtggc gaaccagaag tgatcggttc aacagaagaa taatactgaa
     3541 acaatcaggt ggtgttagaa gcggcgggtc agcagctttt aacacgcctt ttttatttct
     3601 aatcgtttat tttcatatgg ggcttccact tttgtaaatg gctttacaaa cgaaaaatcc
     3661 taatttacca agcttttcct cgcatacttt tatcgtacct ttataaaaat ttatactttg
     3721 aaaaaaagta ttcaattatt gttgcatttt tcctgattct ttattagaat gaaccctcgt
     3781 tgaagtaagt atttctagtt tatcctagga ttaattataa aaataaaaca ttcgttgatt
     3841 cgaaggaggt taaacagatg tttgaaagtt ttgatagcag ccgcaaccgt tacgcttcag
     3901 ttggtgtcgt atcaagtttg ccagatgaat tgattgacag tatatggttt attattgacc
     3961 tagatcttaa gggagtcatt ccattagaaa atatattaac ctttgatttg atcgaaaatc
     4021 gtggaaaagt gacgatgcat ttttctcaag caggaagcaa tgtggaaatg gatattgatt
     4081 tgccgtttgc ctattcgaac caatttcctg ctcaagtata cgcctatgat gacggtacga
     4141 gagaaacgat ccttttacca agtgagatta gacaatatta aggtgataga taaacgtgga
     4201 tgtcccttat tttacagacc aggccaagtt gttgattctt tgactcaatt cttggcttct
     4261 ttttatggag tttcataaat tatcattgat ttctaattgg tattctcagg ataaacgcta
     4321 tatactacta actaaatttt aaagatataa ggagtttaaa agatgcgcga tttaacaaaa
     4381 ggaagccccg ctaaactgat tttgatgttc actgttcctt tactgatcgg aaatgttttt
     4441 cagcagttct acaatatgat cgatatgatc atcgtgggtc agacgctagg taaaaatgcg
     4501 ctggcagcgg ttggtgcaac tggaagcctg acatttttga tcattggctt tgcccaaggt
     4561 ttaacagctg gtttagccat tattaccgca caacgttacg gtgcaaaaga ttatcggggt
     4621 ctgaagaaaa gttttgctgc tagtgttgtc attagtcttg tcgtcactgt gattttaact
     4681 gtcctaagtc tcctgtttat tcgtccgatg cttcaattga tgcaaactcc tcctgaaata
     4741 cttgatcaag cacaaacatt tatttcaatt attttattag ggatctttgc atcagtcagt
     4801 ttcaatttgc tttctaatgt cattcgcgca cttggtgaca gccgcacacc actattcttt
     4861 ctgatcattg cggtcatcat caacgtcgta cttgatttga tctttattat ctattttggc
     4921 atgggtgtgg aaggtgcagc tattgctaca gtaatcgcac aagtttcttc cagcgtactg
     4981 tgtctagtgt atatcaagaa aaaaatgcct ttgttacagt tacgcaaaaa agatttcaaa
     5041 tttgaaaaag aagagtttgc tgtacaccta aatgctgctt tgccaatggc gtttcaatct
     5101 tcgatcatcg ctgttggtgc tatcgtgtta caagcagcac taaatagtct agggacagat
     5161 gtcgtagctg ctcaagccgc tgctggtcgt atcgaccaat ttgcaaatca gccgatgatg
     5221 tcatttggta ttgcaatggc aactttcact gcacaaaact atggtgcgaa agaatatggc
     5281 cgaatcttgc aaggggtacg tcaaacttta ctgatgagtg tcggatttag tctcttagca
     5341 ggtgctatcg tcattttctt cggtcatttc tttgttcaat tgtttgttag cccatcagaa
     5401 acacgtgtat ttgaattagc acaaacctac ttcaatatca atgggtctct ttactggatc
     5461 ttagcagtcc tgttcatttt acgctacaca cttcaagggc ttggacaaag caagatccct
     5521 acgatcgccg gtatgatgga attgcttatg cgttcttttg cagctatcgt tcttacagga
     5581 atgtggggat acccaggagc agcagcagct tctcctttag cttggatcgg ttctgttgcc
     5641 gtgttgcttt actcttatat gcgttcgatg aaacaattga aacacatggg tgaagaggaa
     5701 catttcacat tagaacatgc agaagcaaga tagccttgat taaaagaaat cgttgcggct
     5761 aaaaatgaaa acttttattg aaaatatctt cttcgtttac cgaaaacagg ttttttagat
     5821 aacaaaaagg ctgtgacaaa aaatgtcaca gccttttttc ttttattcta tttttctttc
     5881 cgtggactct actttgaaat aatcgatatg tgcatgctgg tattctaata ccgtgaaacg
     5941 gaatgatgca atctcaatga ttgttcctgc ttttatttct ttatatcggc tagaagcaaa
     6001 gcccgcaagt gtagtaaaat tcgtttcttc aaactctgga atctctacat gaaaataacg
     6061 ctggaaatca tctaatgtta gtttgccgga gatgatataa gagccatctg actgttccgc
     6121 tatcaatgct tcgtccaaat ctgtctcatc tcggatttcc ccgacgattt cttctaaaat
     6181 atcttcaatc gtcactaagc cgcttgtccc tccgtattca tcttttaaga tagcaatatg
     6241 ctttcccttt tttcgcatga tcgtcaataa tttttttata gggatcgttt cagttgttac
     6301 gatcggctct tcaatcaact gttctactgt cagctggtca tctttataag attgcttgat
     6361 caaatctggc aaggtgacat aacctaaaac attgtctttt gattctaaga taaccggata
     6421 gcgagtatgt ccttgttcaa tcgaagcttt tatcgcttct ttgacggttt ctgaagcttc
     6481 gaatacttgc atggacgtac ggtctacttg tatatctttt gccaaggtat catcaaattc
     6541 aaacacgttt tccaaataat gatattcttc tttggtcaac tctccttttt cataagaatt
     6601 caatgcgact aatgtcagct cttcttgaga caatgtctct tctccttcag atacgagacg
     6661 cacacctaat agcttcccta gccctgcagc tgaatgattc aatacccaaa taaaaggaaa
     6721 cattacttta taaaaataat gaagtggttt aactacgaac aagacgacct tctccgtatt
     6781 gacgatacta tagctcttag gaagcagttc gccaataacc acatcgatat acgtaactaa
     6841 aataaatccc agcgccacag agattgtact gctaatagcc gaactaaaag gtagtttacc
     6901 gatcactggt tctagtaaag ccgcgacaga tccttcaccg acccacccga tgatcaaacc
     6961 ggttagcgta attcctaatt gactagctga taaatagtta tctaaatggt gtgtaacatg
     7021 aagagctagc ttggcgttct ttacattttc cttttctagt tgttccaatc ttgatcgtct
     7081 gattttcact aaagcaaatt cacttgctac aaaaaatgaa gtaattgcaa tcatcaaaaa
     7141 taaaataatg aaattgataa ccatattctc ccgcctttct ctttttctat tgtacccttt
     7201 ttctacaaaa agattgaaaa taatgcgtat tcatatttag gaataaaaaa ggagatgcgg
     7261 catttttcag ccacatctcc ttatcacttc aaaatcattg cgttacttgt tgctaaacag
     7321 ctttttcatg acctctgata aacggtgttc aagtagctga cattcgacat tagttcaggt
     7381 caaagcgcta ctttcacaac cgctctttca accatgtttt ccgagtattt ccaatgataa
     7441 gcggaacagt ttcatgtttt acttcgctgt actctagccc aaaccatgtt tctggcgagg
     7501 tagcgatttt tttgattgcc agttttgcct gcatgatttg acgttgccat tttcctagag
     7561 ttgtcacatt ggaaactact tcatcaatca ggacaaattg gaaatcgcca acttctcgcc
     7621 ctggtgtcag agagtatctt tgtggctgtt ttggcaaacg gccttgtttc atcaaatcat
     7681 ggatgacttg gcgaacatat acgttgattt cctgttggac cctgaaacct aagaacagat
     7741 tcacttggac aataaaatca gtgtccatca tatctacttg atattctttc gtatatggct
     7801 catccgtcac ttccacatga acaaaccaat agactcgtgc tcttttaggc cgtttatcta
     7861 aaatcgaata gatgaactgt cggccaactt tatcttcagc catatcagga accaagaaga
     7921 ccacatttgt ctgatagatt ggtaaagaag tatcatcacg taattctcta agctgcggga
     7981 tataatctct caaagacaca tcctcggttg acgattcgcg aataatgttc ccttgttccc
     8041 aaataaacat cacgactaag atgatcaaac caatcagaac ggctacaaaa ccgcctcgga
     8101 agaatttgac aacacttgag ataaagaaaa cgacttctat cgcaccgaag aaaaaggtaa
     8161 ctaaatatgc aagccaacga gaatgcccat tttggataag ataaaagtaa agcagtgctg
     8221 ttgtcatcaa catcgtcaca gtgatcgata gaccgtaagc agcttccata tgatgagacg
     8281 ttcggaatgt gacaaccact agagaacagg cgatccataa aatcagattg actgctggga
     8341 tatacatttg cccgatactg ttcccaggat acatgatctt taaccgaggc agcagtttca
     8401 acttgattgc ttctgaaact agcgtaaacg aacctgtaat caatgcttgc gaagcaatga
     8461 ctgcagcgac tgttgcaaaa gcaacgccga tcacgatcca actttgaggc atcatttgga
     8521 agaatggatt caggttcttg atttgctgtg cttcagggtt ttgataaaca ttcaacaacc
     8581 acgcagcctg cccaaaataa ttgataacca aacaaatttt gacgtaaggc cagctcagac
     8641 gaatatttcg tttgccgaca tgtccaagat cggaataaag cgcctctgca cctgtcgtag
     8701 ccaggaaaat atttccaaga atgaacaagc ctaatttgtt atctgcacta aaaagcagct
     8761 ggatagcata ataaggattc agtgcacgga taactgtcca gtcttgactg aagttcatta
     8821 atcccattac gcctaaaaaa gtaaaccaag cgaacatgat tggtccgaat gcttttccga
     8881 caatatctgt accaaagcgt tggaccatga ataaaacaaa aataataact aaagtgataa
     8941 tgacgatcac gttctggtta ttaccgaacc ggtcaaaaaa ctgcggaatt cctcgcaagc
     9001 cttcaatcgc agtcgttacc gtcacagcag gggtcaatac cccatctgct agtaaggcag
     9061 ctcctccgat cattgcagga atgatcaaat atttcccacc ttttcggaca agtgtgtaga
     9121 gtgagaaaat tccaccttca ccatggttat ctgcattcaa tgcaatcacg acatatttga
     9181 ttgttgtcag tagagtcaat gtccaaaaaa tcaatgagac tgatccgata acaaaatcag
     9241 gattgattcc tgacaatccg ccattatctt caacaatcga tttcataacg taaagcggac
     9301 ttgtcccgat gtctccgtag acgactccca tcgctacaag caggccagcc attgatatct
     9361 ttttggtatt gtgcgttgtt gccacgtttt tccctcattt cttgttatat ggatatcctt
     9421 taggtaagct tgaatgatag atgatattct tatccatgac acccgctttc ctaaattgct
     9481 tctaattatc caagtaacac actgaagtgt caacttattt gaataaaatt attctttctt
     9541 tggacgttct ctgatacgtc ttgccacaaa tgaataaaga gcaaggcaaa aaattgcacc
     9601 caataatgct ggtatcaaat aaaaaccgcc gagttccggt cccagtggtc ctagtaaaaa
     9661 ttcgccgagc caactaccta aaaaaccgat aatgatattt ccagatacgc ctcccgggac
     9721 ttcctttcct aaaattgcgc cagctatcaa acctaatata ccgccgataa ataacgacca
     9781 taaaaaattc agcatctcct ttccctcctt tatccatatt tctcactttt attttacgct
     9841 ttattcagaa ggactccaaa aatatgcgcc aagaaactcc agaaaaaaag aagttgtaac
     9901 aaaagtgttc agcttatttc cgtagaagct gcttctggaa caccgtgaat cagaggttgt
     9961 gaaatcagcg gtttgacctg agtattagag aaacaaacgg aaaaatagtt cctcatattt
    10021 tgccgttttt tgagctaata tcgagggaca gctgattgaa catcgtttat tggagaggtt
    10081 gtaaaaaagc tgttctgcat caagtaataa gaacagccaa gtaaaaacag ctcctaatgt
    10141 ttttaacttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt ttattcgaaa
    10201 aaaaaggact gtgacacggc ttttgtcaca gtcccctttt ttcgaataat tattgtcccc
    10261 ctgtcacctt cacgatcaca agtacattat tcctatgaat taaattattt ttcttcattt
    10321 ttcgttgaac catcttcgtt caacattgct tttcttgaca gatttacgcg tccttgttta
    10381 tcgatttcag ttactttcac aaggatctca tcacctagtt taacaacatc ttcgacttta
    10441 ttgacacgat cgtttgctaa ttgggaaata tggacaagtc catcttttcc tttgatcaag
    10501 ttgacgaatg caccgaattt ttcgatacgg acaactttcc ctagataaac ttcaccaact
    10561 ttgacttctt tggtcaaatc ttcgatgatc ttgatagctt ttttgatcat ttctgcatca
    10621 gctgaagcaa tacttacttt tccatcttga tcgatatcga ttttcacacc agtttcatcg
    10681 atgattccgt tgatcgtatc gccgccttta ccgataacat ctttgatttt agcaggttcg
    10741 atctggatca tttcgatttt tggtgcatat tggcttaatt cttcacgtgg agcagcaatc
    10801 gttgaagtca attcttctaa gatttccata cgtgcttgtt ttgcttgagt taatgcttca
    10861 gttaggattt gttctgtgat tccttgaatc ttgatatcca tctgtaaagc agtgatacca
    10921 tcttttgtac cggcaacttt aaagtccata tcgccaagat gatcttccag cccttggata
    10981 tcagttagga tcgtatagtt ttcaccatca gaaacaagtc ccatcgcaat accggcgact
    11041 ggcgctttga ttggtacacc tgcatccatc aatgctaatg tgccagcaca gatacttgct
    11101 tgggaagaag aaccatttga ttccaatact tctgctacta aacggatcgt ataaggaaat
    11161 tcttcttctg aagggattac ttgtgctaac gcacgttcac ctaatgcgcc atgtccgatt
    11221 tcccgacgcc ctggagagcc tgcacgtcct gtagaaccaa cagaaaattg agggaaattg
    11281 tagtggtgga tgaatcgttt gctgacttcc acccctaaac catcaatgat ttggtgctct
    11341 cctagaggtg cgagtgtaca agctgataaa gcttgtgttt gtcctcgtgt gaacaaacct
    11401 gatccatgta cacgtggcaa taagctgacc tctgatgaca atggacggat ttcatccaat
    11461 ttacgcccgt caggacggat cttatcgatg gtgatcaatt cacgtacgac atctttttca
    11521 agatcttctg tgatttgttt aacttctttc aacaagtgat cttcatcttc atgacctgca
    11581 aatttctcag cataagcttc gcggatatcg atcttcacct gctcgatatt atcttcgcga
    11641 gcaagttttt cttcagtcat tactgctgct ttcattgtag cgtaagaagc atcaaagatt
    11701 tcttttttca atacttcatc aacttgcagt aaagtcactt ccattttttc tttccctact
    11761 gcttgaacga tttcttcttg gaaagcaact aactctttga tagcgtcaaa accaaacagc
    11821 aatgcaccaa gcatgtcttc ttctgaaact tctttcgcgc cgctttcaac catattgatg
    11881 gcttgtttcg ttccggcaac agtcaattcg atatctgttt gttctgcttg ttctactgtt
    11941 ggattcaaga cgtactcgcc atttacacga ccaacttcta cgcctgcgat tgggccgtca
    12001 aatgggatat ctgagattga tagtgctaaa gaagaaccta gcattgctgc catagctggc
    12061 gagcagtctg tttctacact catcacgatg ttcgttactt ggacttcatt acggaagcct
    12121 tctgcaaaca tcgggcgaat tggacggtcg atcaaacggg cagtcaatgt tgcttccgta
    12181 cttggacggc cttctcgttt gatgaaacct ccagggattt tccctgctgc atacattttt
    12241 tcttcataat tgatcgttaa tgggaaaaag tctgtatctt ttgcttcttt agaggccaca
    12301 gctgcactta agactactgt atctccataa cggactaaaa cggctccgtt tgcttgtttt
    12361 gctagctgac cgacttcgat ttgtaaggga cggccgcccc atgtcgtttt gaatacttgt
    12421 ttttctgaca taacttctcc ttttccttct cgtgaaagca agacgctact aaacaaatga
    12481 aaactgccga aagccgtctt ttgagcagct ttcatttggt tagtaggagt ccatctagct
    12541 tgatcacgga attttactta attgatatac gagtaaaaaa agtgagattc atgtgaatcc
    12601 cactcttttt gactaaaatt aacgacgcaa gcctaaacgt ttgatcaatt cgcggtaacg
    12661 ttgaacgtca gttttacgta agtaagctaa caagttacgg cggtgaccaa cttttttcat
    12721 taggccgcgg tatgaatgat ggtctttttt gtgcacgcgt gcatgttcat tcaagtggtt
    12781 gatttcttca gttaatacag cgatttgtac ttctggagaa ccagtatccc cttcatggcg
    12841 agcgtattcg ttgatgattt cattcttgcg ttcttttgaa attgccattt ctttcacctc
    12901 tttcgattat tcccctgcga ctgagtaaaa cgttggtgat tcgcttaacc aagtggcagg
    12961 tcatgtgcct agagcacaca gctatacttt acctgaaacc gggttgaaaa tcaagtagtt
    13021 aatcattaag aaaaggtagt tttcaaacaa tcttactact acttttccat ttttgtggta
    13081 aactataatg cgaaaataga cttgaaacac agtcttttaa gaaaggggta catattccat
    13141 gattacaatg gatgatatca ttcgtgaagg aaatccgacc ttacgcgaag ttgcaaaaga
    13201 agtttctctt ccattaagcg aagaagatat ctctttagga aaagagatgc ttgagttctt
    13261 aaaaaacagc caagatccaa tcaaagctga agaactacac ttacgaggcg gtgttggctt
    13321 agctgctcct caattagata tttctaaaag aatcattgct gttcacgtac caagtcctga
    13381 cccagaggca gatggacctt ctctaagtac tgttatgtat aatcctaaaa ttttgagcca
    13441 ttctgttcaa gatgcttgtt taggggaagg tgaaggctgt ttatctgttg atcgagaagt
    13501 accaggatat gttgttcgcc atgccaaaat cactgtgtct tattatgata tgaatggtga
    13561 aaaacacaag attcgtttga agaattatga atcgatcgtc gttcaacatg aaatcgacca
    13621 tatcaacggt gtgatgttct atgaccacat caacgatcaa aatccatttg cactaaaaga
    13681 aggcgtattg gtgatcgagt agagaattgg caggttcctt cgatactatg ctacaagaaa
    13741 gctttataaa aaaggggagt gctcaaaagc tgcacttccc ttttttatgt ttctccacta
    13801 atcgaaattt agatagacat ctagaaatcg caattccaaa aaattctgtg tattggatac
    13861 gcatcttttc ttattttttc ttatttcttc catatgggtg tttatctcag agatgataga
    13921 atagtttcta ggataaaaag tagcagctac gatgttatcc ttcgtagagg attcctgctt
    13981 cagctagttt ttgtttgatg tttttcagca tatgcttttc tgggtagcgg atcgtatgca
    14041 gatggatgcc gcctgttaat tcggataaca aagtagcatt acttttttga taacgtctca
    14101 taaaggaatc gatatcttgt ggcgttttga tgtgcaaagt tcctgctaac tcaccgtaaa
    14161 ggggatgttc cacaattaca tcaatgattt caccaccatt ttcaacgatt agtctcagtt
    14221 cttcttctgt ttgatctttt ccatgctgga cagcgatttt actgatgtgc ccagtattgg
    14281 tttcttctgt ttcgaggata taacctcttg ctgttgccac gatactttta cctgcagctc
    14341 gtagtaaagc aatatcgcct acaatgatct gacggctgac tccaaaagtt ttcgcaaact
    14401 tgctagcact cactggtttt tctgtatttg ccaaggtttg catgatttgt tttcgccgtg
    14461 tctctccttc gatcacactt attcctcctt cattttgttt tggtattcgc gcgagtgttt
    14521 catcaaatca acatacgtgt ctgttattgt ttccttatat cccttatttt tcagcagact
    14581 aacaacttta tccaatactt gctgctctct ttttgcatca taaactgctt ggttttcttc
    14641 ttttttcact tgtcctattt tagttaccgt atccattctt ttttctaata aagcaaccaa
    14701 ctctcgatcg atcatatcga tcttatgacg taatgtttca agagactctt ctgttagttc
    14761 ttcctctact gtcttgatga tacgagcagg atttcctgca atcactacat tgtcgggaaa
    14821 agatttggtc acaaccgaac ctgcgccgac tactacgttg tcccctagag tgacacccgg
    14881 cgtgacgata actcctccgc ctaaccaaac attattaccg attttaatgg gttttgcgta
    14941 ctccagaccg ctgttacgtt tcactggatg tagtggatgc gtcgccgtgt aaagctggac
    15001 attcggagcg aacatgcagt tatcaccgat ttcaatcgtg ctgacatcta aaaatgtaca
    15061 attgaaattt gcataaaaat tctccccaac aaatatatta tatccgtaat caaaattgat
    15121 aactggctcc atatagattt ttttccctgt acggccaaaa gtctctttca acaattggga
    15181 tcgcagttcc gctgattctg cttggttgat gatttggctt tgacttcttg caaacatacg
    15241 gtcggcaacc agctcaggat cattggcaaa ataaagctcg cctgcaatca ttttttcttt
    15301 ttcggttttg aattcagtca taatctgctc ctaattcttg tatttttttg aaaacaaccg
    15361 ctccgtcttc ttgaataaac gtataaggct ccgctaaata aacaggcgtt tgattgatta
    15421 ctaagatttt ggctgacggc tggcgaaact gtaccagatc acaaaacgga tgaacttgaa
    15481 aactcgttcc aacaatgacg atcagctctg cttggctgac ggcataagcc gcctgctcca
    15541 tgactccatc ttgaaaccct tcaccatata acacgatgtc tgggcgtatt tgtcctccgc
    15601 atgcttgatg tttgtcgctg tgaagatatt ctttccagtc taccgtttgt tgacattttc
    15661 gacaatgaca ttgatacaga ctcccatgaa aattgacgag ttgcgggctt ttagcctttg
    15721 cgtgcaaacc gtcgatgttt tgggaaacaa cccaaacatt tttttctttc gctagatgtg
    15781 ctatttccaa atgaatgata ttgggttttg cttcaggatg ataaatcttt ttgacaaatt
    15841 gatagaattt atccggttca ttcaccattg cttgatgact cagcaagtat tccggctgct
    15901 ccatcccgtg gtagattcct gacaaagatc gatagtctgg cactccagaa ggtgtggata
    15961 cccctgcacc ggtcaaaaat gtaatttgct gataagctaa tatctctttt gctgcttcgt
    16021 ctactgttaa ttgtttcatg ttttgtcacc tcactttcca ttatagccca tactcgaaca
    16081 aatttattgt tgaaaagtca gaaaaatggg aataaaaaag tgttatgggc atttgagcaa
    16141 tttatcacaa tgttcactga caaaagaatg aaaacgtgtt acaatactgc tgtataaaag
    16201 tgaggtgaat cgatatgtta ccattcttta tttattgggg cgttattctg gcttgtatcg
    16261 cctggttagc gttaagcgtt tatttctctg ttttttatct tgtacgcaaa gaaaatggaa
    16321 atctttgggc ttttgcttta ttcaacgtga ttgccgcaat tgttttagcc attacattag
    16381 ccgtatatcg aacatggggc tggggaatca cccaatactc aagtttgatt tatctaatat
    16441 tagccattta tggcgtcgtt gttcttttgc aagcgatcct aggacgtgag ccaaagaaag
    16501 cggcagctta aatgatcgag atggaactgg acacaggaaa ttttctgttc tagttctttt
    16561 tttattgtat tacatacatt tttgtgtata attatactat cgtttgcaat ggatagatga
    16621 ttcacatttt gattgttttt tcggtaaaag taaagatttc tatatttatc agtatttttt
    16681 caaaaaccag cagttataga ttgacaaagc ctctcgagta tcgtaaactt tttttgtata
    16741 aataactgaa tacgagatgc ctcaatcaat gaggtagagg tcgcgagaat cattaaccct
    16801 gtggagtgaa gcaaacatgg agaagcagga atagggagga tcgccgaaat gtgcactttt
    16861 ttgcttggag tgtatgttgg gacgcaagtt aagagcttgc ggactgtctt agcagtgatg
    16921 ctaagttgcg ctatgttttg tgagaggttt atcaccttat ggaattttag cggccttttt
    16981 atatctataa atcggtcgct ttttattttt tcagataaag ctttaccgca tttcatctag
    17041 accgctcgtg tatcatataa tcagaaaggg agaaaaaaat gaaaaaaaat atggtttcag
    17101 ttgccgtact atttgctttt gtcttctcac tattcagtgt gggatctctg gcaaatgcag
    17161 atgaaaaaac accgagcgat gagtttcgcg taggtatgga ggctgggtat gcacccttca
    17221 actggtctca acaaacagat gagaataatg ccttgccaat tcaaggccaa aatagttacg
    17281 ccggcggtta tgatgttcaa atcgctaaaa aagtagcaga tggtttaggg aaaaaattag
    17341 tcatcgtcca aacgaaatgg gatggtctgg ctcctgccct tcaatcaggc aagatcgacg
    17401 cgatcatcgc cggaatgagc cctactgctg aacgacgaaa agaaattgat tttaccgatc
    17461 cttattacga atcacaatta gtagtagtag ttcaaaaaga tagcaaatat gcaaaagcaa
    17521 aaagtttagc agatctttct ggagcaaaga tcactgctca gttaaataca ttccactata
    17581 ctgtgatcga tcagatacca gatgtgcaga aacaacaagc aatggataat ttctcagcaa
    17641 tgagaacagc tttagcttct ggaatgatcg atggttatgt cagcgaacgt ccggaaggtg
    17701 taacggcaac tagtgtgaac aaagacttgg aaatgcttga attcagcggt gcagatggct
    17761 tccagacaaa cccggaagat gttcagattt ctgttggtat gcgtaaaggc gacccggata
    17821 tccaaaaagt aaaccagatt ctttctggca tctctaacga tgaacgaacc aaaattatgg
    17881 accaagcagt caaagatcag cctgctgcaa ctgatagtga agaaaaacct ggcatcattt
    17941 ctgatttcac tacgatttgg aaacaatacg gcaatatgtt cttacgaggt gctggactta
    18001 ccttgttcat cgcattgatc gggacagttg tcggtactac acttggatta ctgattggtg
    18061 tcttccgttc ggtacctgaa tcaggaaatg cactgactcg cttcttccaa aaaatcggaa
    18121 atgcacttct ttctatctat gtcgaagtat tccgcggaac accgatgatg gtacaagcaa
    18181 tggtcatctt ctacggtctg gcactcgctt ttggcatttc attgaaccga acgattgccg
    18241 ctttgtttat tgtctctctc aatactggag cttacatgac agagatcgtt cgtgggggga
    18301 tttttgcagt agatgaaggg cagttcgaag ctgcgcaagc cattggtatg acccatggcc
    18361 aaacgatgag aaaagttgtt attccacaag ttttacggaa tatcttgcca gcaacaggaa
    18421 atgagtttgt tatcaatatc aaagatacag cagttttaag tgtaatcggc gtagctgatt
    18481 tgttcttcca aggaaactct gcttccggtg cgaatttcca attcttccaa acatttacga
    18541 tcgtcgggat catctactta gtcatgacct ttacgatcac cagaatcctg cgggcggtag
    18601 aaaagaaaat cgatggtcct tcagcttata ccaagcttga agaaatcgac aattcaaatt
    18661 tgcaggaata aggaggaaga atcatgaatg aaaaaattat tgaaatcaaa catctaagaa
    18721 aaagcttcgg tgaaaatgaa gtattgaaag atatcagcgt aacagtcaat aaaggtgaag
    18781 ttgtgacgat catcggttct tccggttctg gtaaatctac tttcttgcgc tgtatcaatt
    18841 tactggaaaa accaacaggc ggcgagatca tttataatgg agaaaatgta ttagctccta
    18901 aatataattt acctaaatat cgaacgaatc taggtatggt tttccaatcc ttcaacctgt
    18961 tcaacaatat gaatgtcttg gaaaactgta tgtctggtca aacaactgtc ctgaaacgag
    19021 ataaagaaac tgccaaaaaa gtagcaatcg aaaatctgga aaaagttggt atggatcgtt
    19081 atatcgaagc caaaccagca caattatctg gtggacagaa acagcgtgtc gcaattgctc
    19141 gggcattatc aatgaatcca gatgtattgc tattcgacga acctacttcg gcgttagacc
    19201 ctgaaatggt tggcgaagtg cttaatacga tcaaagactt agcacatact ggcttgacaa
    19261 tgcttatcgt gacgcatgag atggaatttg caaaagatgt atctgaccgt gtcattttta
    19321 tggataaagg tgtgattgca gaagaaggta caccagaaga tatctttgtc catccgaaag
    19381 aagaacgtac aaaagaattc ctttcacgta ttttaaatgc ttaggatcaa tagctgattg
    19441 ggacaaagag ctgcggtgtt taccgcagtt cttttttatg aattactcat aaaaggtaaa
    19501 tttctgaaaa ttttggaatc ttagttgtgt ttttcagaaa actctcttaa tatggaagta
    19561 attaaacttt tttagttagg atgatttaaa aatgaatgaa gagcaagaac tgcagcgtgg
    19621 actgaaaaat agacatgtcc aactgatttc tattggcgga gcgattggaa cggggttgtt
    19681 tttaggttcc ggaaagtcta tccagctagc tggcccttcg atattgctcg cctatcttat
    19741 tactggatgc atctgttttt tcattatgcg tgcgttaggc gaacttctgt tatcaaacac
    19801 caataaccat tcttttctgg attttgttgc agaatatctt ggcaaaaaag cggctttcat
    19861 cactggctgg acgtattggt tctgctgggt atcgattgca atggccgatt taacagccat
    19921 cggaatgtat gtacgctact gggcgcctgg tgttcctcag tggcttcctg aactgattgc
    19981 attaggtctt cttctttgct tgaatatggt ggctgtctca ttgtttggtg agttagagtt
    20041 ttggtttgca ttgatcaaag ttgtagcgat cattgccttt atcctcgtag gagcttatat
    20101 gatcctcacc cactatacga cagatattgg cacagccagt atcacgaatc tatggtctca
    20161 tggcggattc tttccaactg gtgcaaaagg atttatctta gctttccaaa tggtaacctt
    20221 tgcttttgct gggatagaat tagttggatt agtcgctgga gaaacagaaa atcctgaaaa
    20281 agtgttgccg gaagctatca ataatattcc tatcaggatc atcttatttt acttaggatc
    20341 tctttttgtc attatggcaa tctatccatg gaacagcttg aatccagata acagtccatt
    20401 tgtagaagta ttttcggaaa ttgggatcac gattgctgct tccttgatca atttagtcgt
    20461 attaagtgca gcagcttctg cctgcaacag tgcaatatat agtacaggac gtatgcttcg
    20521 ctctttagcg caagaaggca gtgcccctaa aaaattcaaa aagttaacaa cacatcatgt
    20581 gccagggaat gctttgacat tttctactat cgtcattttc atttctgtta tcttgaatta
    20641 cgtgatgcct agtgaagtat tcacactagt aagcagtatt gccactactt gtttcttgtt
    20701 tatctggagt atgcttgtct acacgcacat gaaatatcgt aaaagtatcc tcggcaaaaa
    20761 agctcattca tttaaaatgc cgttgtaccc atttagtaat tatctggtat ttctttacat
    20821 ggcctttgtg tgtgtcgtct tgttcctagg aaaagatacg agaatcgctt tattactaac
    20881 acctgtgtgg ttcttgcttc tattactaat ctatcatatg aaatatgaac gtaagaagta
    20941 agaaagtagt tgtgacagaa gtggtcagct tcgagaaata agaaggaatt tacgaaaatt
    21001 gcttcttaaa tttttgtgaa atttcggctt atttcttgga gataaaagct tctgtcccag
    21061 cctcttttct atttccccgg aaacaaccgc tgataatagg catctgcttt tttataggaa
    21121 aaaatccaaa taccagatac aaaaaaacgt ccgaataacc cgatcaacgg tacaaaaaag
    21181 acaccggcaa tcaagcataa gttaatcatc atggagataa gacttcgacg gtcctttgac
    21241 aaaactctca cgacatggga atctggttta tttgctttca tgatttgcct catcaagata
    21301 ccaaaagaaa aactccacat cgtgtatact aagacataag ccatctcagg ccaaaaagct
    21361 tcagggttac gcccgaccca actagtaaca gaaggacata aagtcagcca aaagagcaaa
    21421 aagatattcg accagaccac tcggtaatta attcgttctg ccatctgaaa tatacgatga
    21481 tggttcaccc agatcaccgc aacaaatata aagctgatgg tataagctaa taatgtattt
    21541 cggatgaccc ataaagaatg aaagctagat gtattaggga tcttgatctc taatacaata
    21601 actctcaaaa caatggctac cactccatca gtaaatgctt ctaatctcga ctttgtcacg
    21661 atgattcctc ctcagatgat tcagcgcttt tattttatca cttacgttat taaataacca
    21721 tcgttttata tagggaattt tctgaaaatt gttgcatatt tttcgaaatt ttgttacttt
    21781 taaaaaaacc gtaaaggagt tatgtatgac aaaaaaatta tcatttaaag actatctttt
    21841 tataggctcc atgcttttcg gtctattttt tggtgctgga aatcttatct ttcccgttca
    21901 tttgggtcaa gaagcaggcg ctgctacctt ttgggcgaat ctaggtttct tggttaccgg
    21961 tatcggtctt cccttcttag gggtgattgc cattggtgta tcgaaaagct caggtgtata
    22021 tgaattagca aaacggataa atcaaacata tgcgatggtt tttaccatct tgctttactt
    22081 agttatcgga ccgttttttg ctttacctcg ccttgcaacc acatctttcg agattggttt
    22141 agcaccattt atcgatccta gcagacagac gctatatcta gcaattttca gtattgtatt
    22201 ttttgtgctg gcttggtggt tttcaagaaa accgacaaag atattagatt atgttggaaa
    22261 gttcctgaat cctgcatttt tggttttatt aggtgctttg cttctccttg cttttttgaa
    22321 tccactaggt tctgtaaatc aagcgcctat tcagccaaat tatcaagagc atgctttttt
    22381 cacagggttt actcaaggat ataacacatt agatgcgctt gctgctttag catttgggat
    22441 catcattgtc acaacaatcc aaaacatggg tgtaacaaaa cctgctgaaa tcgctaaaga
    22501 cacgatcaaa tctggtgcga tcagcattat attgatggga atcatttata ctttgctcgc
    22561 ttatttaggt gctatgagct taggtagctt tgctctaagt gaaaatggcg ggatcacgct
    22621 ggctcagatt gctgatcatt atttaggtac ttatggcagt atcttattag catttatcgt
    22681 tatattagct tgcttgaaga ccggtattgg tttgattaca gcttttgcag aaacattcac
    22741 agatttgttt ccgcaaagaa attacgcatt ctttgttgca cttgctagta tccttccttg
    22801 tttagcggca aacgtaggct tgacgaatat cattcaattt tcgttgcctg ttttgatgtt
    22861 catctatcca ttagcaatga cactgatttt actagtgtta gttggtcctt tgtttaagca
    22921 gcgtacggct gtttatcgaa tgactactta ttttacattg attgcttcga tttttgatgg
    22981 gttgaacgct tgcccagaaa ctatcaaaca aacacctatt gttcaaaatc ttttatatgt
    23041 tgcggaaagc tacttgccgt ttttcaaatt ggggatgggg tggatcgtac cagcagttat
    23101 cggttttgtt atcggactga tttggagttt cgctaagaaa gaagaagtag cagattgata
    23161 aaagaggttg tgaaagagac gttcagcctt gagcaataaa aagtaatttt gaaaaatggc
    23221 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctgacttttg aacaccgttt
    23281 attgagaggt cgtgaaaaag ccgcttagtt tcaagtatta agaaatattt tgtgaaaatg
    23341 gcttctcaca tttttgcata aatttgactt aataccgaga aactggcttt tgaacaccgt
    23401 ttattgagcg tctataaact gacctgagta ttagagaaac aaaacggcaa agtagctcca
    23461 tatactttgc cgttttgttt tgaactaata ccgaagagaa gctgatcaaa caacatttct
    23521 tttataatat agattttaga catatatatg atataaaaat agttttcgca aaa
//
LOCUS       DAJSMK010000036        23432 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.037, whole genome shotgun sequence.
ACCESSION   DAJSMK010000036 DAJSMK010000000
VERSION     DAJSMK010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.037"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(10..2154)
                     /locus_tag="ON488_001425"
     CDS             complement(10..2154)
                     /locus_tag="ON488_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HCR3231626.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQTADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFEPVPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2511..3884)
                     /locus_tag="ON488_001426"
     CDS             complement(2511..3884)
                     /locus_tag="ON488_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3231627.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPIMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="ON488_001427"
     CDS             complement(3884..4279)
                     /gene="rbsD"
                     /locus_tag="ON488_001427"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HCR3231628.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGSEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="ON488_001428"
     CDS             complement(4307..5224)
                     /gene="rbsK"
                     /locus_tag="ON488_001428"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HCR3231629.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(5333..6346)
                     /locus_tag="ON488_001429"
     CDS             complement(5333..6346)
                     /locus_tag="ON488_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCR3231630.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQISHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEESGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(6427..7029)
                     /locus_tag="ON488_001430"
     CDS             complement(6427..7029)
                     /locus_tag="ON488_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCR3231631.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKGIVNNGTLSPHTAQSILTNN
                     DLLAKTLKRTAALKVLVNVDITTFSYLSHQTDAGGISALSAPAEFTDLLLKDSLKDTN
                     NMLTITKYNPSAFFGTSLDLQLRRRGIETIVLSGVATTNGVYATALDAFQHGYHVVLA
                     EDACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            7214..7915
                     /locus_tag="ON488_001431"
     CDS             7214..7915
                     /locus_tag="ON488_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231632.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            7925..10636
                     /locus_tag="ON488_001432"
     CDS             7925..10636
                     /locus_tag="ON488_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231633.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEHNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKITEGKAQIAQGRTQ
                     LEDAKKQLAQQSAAIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKAAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWSYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            11033..12661
                     /gene="treC"
                     /locus_tag="ON488_001433"
     CDS             11033..12661
                     /gene="treC"
                     /locus_tag="ON488_001433"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HCR3231634.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRITIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(12721..13902)
                     /locus_tag="ON488_001434"
     CDS             complement(12721..13902)
                     /locus_tag="ON488_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR3231635.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSVW
                     LVPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            14154..15680
                     /locus_tag="ON488_001435"
     CDS             14154..15680
                     /locus_tag="ON488_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCR3231636.1"
                     /translation="MKRLIGILAMLVLAGMLTACGGASGKAEDSKEKLSVMTTFYPMY
                     DFTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQK
                     TLQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVAN
                     IRDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLAL
                     EYGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGV
                     SLEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNG
                     YFEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGY
                     QTDIASIKISEKEMAFTFKDGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGA
                     FRYIQFSDHTIAPADSEHFHLYAGNESQEALLKEMENWPTFYPDTMDGREIAQEMLLH
                     "
     gene            complement(15749..16477)
                     /locus_tag="ON488_001436"
     CDS             complement(15749..16477)
                     /locus_tag="ON488_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3231637.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(16490..17770)
                     /locus_tag="ON488_001437"
     CDS             complement(16490..17770)
                     /locus_tag="ON488_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HCR3231638.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIALSAFLSALLAFCFKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYAQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLVVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(17911..18513)
                     /locus_tag="ON488_001438"
     CDS             complement(17911..18513)
                     /locus_tag="ON488_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HCR3231639.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFALEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            18759..18965
                     /locus_tag="ON488_001439"
     CDS             18759..18965
                     /locus_tag="ON488_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231640.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            19278..19997
                     /locus_tag="ON488_001440"
     CDS             19278..19997
                     /locus_tag="ON488_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCR3231641.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(20078..20761)
                     /locus_tag="ON488_001441"
     CDS             complement(20078..20761)
                     /locus_tag="ON488_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HCR3231642.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            20993..23179
                     /locus_tag="ON488_001442"
     CDS             20993..23179
                     /locus_tag="ON488_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HCR3231643.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT         7814 a         4208 c         4582 g         6828 t
ORIGIN      
        1 taatttattc tatttcttta aaggcagatc aagccagaat gatttgtcta aacttaacaa
       61 ggttagtaca ggaacagttg cagctttaac tgtacgagta gttgtttctg gtatctgtct
      121 tgccgtaaaa ttgttccaca aatcccagat tgaagcgaca cggaagatgg aagaagcgtt
      181 gttgacgcgt tttatcgttg aaaattctaa tcctgtgatt ggcacgccat ctgttgtcca
      241 tttgattggc acatcgaatc gcttagacat attgaggatt tcagcgtttg cttcttcagt
      301 tgttgctgct tcttttttcg gttcatcata ttttgtcagg tcgtacgctt cgatgatcgc
      361 gttcaatttt tgtgaatatt ggcgatctgt agcataacgt ccttccaaat atttggttgc
      421 ttctttgtag tcttttgttt ccgacttcca agttggtttg tagaaatcag gattgccagt
      481 cagtccattt ttgatcaagt cggcatagtc ttccaaactt tccttgtaag aaggatattt
      541 acggaattgt gcgcggattt ggtagctttg tccggaacta tcttgttcaa gtgtattgaa
      601 ggtcacgctg cttcctttat atgatccttt gataccaaaa aggttatgat ttggttcgct
      661 tgataataag ctgtttccag atccactttc aaggatagct tgagccatca tgactgatgc
      721 gtagattcct tctttttgcc cgatttcctg tgcatcatct gcaatctttt tcaagaactg
      781 atcagttgtt tggttttgac tgaaatggaa cgagccatct aatccatcta aaatagatga
      841 gccgcctgtc agcgaacctg aagcagcagg taaacctgct aagtttactc ggacagcaaa
      901 atcaggcgtg aaatctgaaa tagaagttac tcgaacttta tctcctggtt gaggcgcatg
      961 gataaattgt ccgttcccaa tatagatacc tacgtggtgg gtaacaccag aagaaggtcc
     1021 ccagaagacg agatcaccag gttgggcctg acttactgga atctgtgtac ctgcatattg
     1081 ctgttcgcct gtccagccac cgatataatg accggttgct ttcatatata cgtaataagt
     1141 caaaccagaa cagtcaaaag tatttggacc ttttgctccc catacatatg gttttccaag
     1201 atgcttgaat gcttctcgaa cgattgcttg ttggacattc gttgtatttg taggcaatac
     1261 agcatcaatt ggtgatttta caacaaaatc agaagaagca gaagatggat tctctatacc
     1321 gctttgattt gctgtatttg gacgagatga agcattgttc gttccgccat ttgatgaacc
     1381 attgtttgga tggtttggtt ctctctgagt atttccattg ttattcgatc cagatgggtt
     1441 tgtttgattc gaagaattcc cgctgttcga attattgtta ttattgtttg aattatttga
     1501 accattatta ttgttgttat tacccacatc tggtttgttt ggcgtttccg gatctggtgt
     1561 actagggact tcttcactag gatcagttgg tttctctgtt gaagtatccg gtacaggttc
     1621 aaattctgca gtaatagata aattgttcgt acctactgta aaggtctttg catcataatt
     1681 tacttctttg gcaccattaa cagcgactga agcaatttgt tcaccttcag ctggcgtaat
     1741 agtgtaagtt accttcgttt ccgctaataa accttctacc gttccacttt ccgtaatatc
     1801 caaaggttgc tgttcagggg aatccgctgt cgaagcagtc agttggatct taccaatcaa
     1861 agaaggagca attgtaaggg aatatgtctc ggctggcttt tcattttctg atggatcagc
     1921 cggatcaatt tcagttggct cggtcgatcc tgttgttgag ttagttgttc cagttgggtc
     1981 ttctgtaaaa gaatccgttg tttcactagt agctgagctg gatgtagtcg tatctgttgt
     2041 gactgtttga tcagctgttt gattatctac ggcaaatacg gtattggtcg acaaaacaga
     2101 cggagcaatc agccaagtag cagctagcaa acgtatcgtt tttttatttt tcataataaa
     2161 ctagtccttt tcctttcatt gattttctgt cttattcagc attcattaga cattttttgg
     2221 aacagataat cgtgtcgaaa agctttttct tttcataaat ctgtctgtgt attctaaata
     2281 aaacaatttg taaataagca acgagcattc attcgttttt cattgacgtt cattttattg
     2341 catagaccac ctttgtttgg ggataaacaa gtggggataa aaatggttat gcatatgtaa
     2401 attataccaa agtttggaaa gtatcacaaa aatttataaa aataatgatc ctaaaaagaa
     2461 aaagactgaa atatgtgata aacatctcat acttcagtct ttttcattaa ctattcataa
     2521 gacattaggt cttcatcaaa cccgctaacg agagtagtaa tcattgctac gactagacta
     2581 acagccagtc ctgctaagta ccagaaaaaa gtaccggaaa tgaatgcagg caatgtggtc
     2641 agactaccaa atacaaaagc gatcgctttc acttgggcaa atcccattac agctccacca
     2701 gcagctgcac caatgcaagc agcaacaaat ggttttttca atgggatcgc aattccgtaa
     2761 acagttggtt cggtcactcc cgcaagtaaa atcgaagcaa aagcagaacc ggagatcgaa
     2821 cgagtttttg aacgtttact tcgtagaaat acacctaaag ctgcaccagc cattccaaaa
     2881 ttggctgctc ctgtcaacgg aacgattcgg tcgaacccat aagcagagat attactgatc
     2941 atgatagggt ttacagccca ttggatacca aatattacca aaatattcca accaccagcg
     3001 atgattgcgc cgctgatcgg tccgttaata tccatcatcc aagtaattgc ggcagctaaa
     3061 ccttcgccaa ggtaaacacc cgcaggcccg aataccatta acgtcaaagg aaccgtgata
     3121 actaatgaaa gtaaaggtac aaatactaat tgcatatttt cgcgaatata ttttttgagg
     3181 aatttttcaa caaaagaata aaagaaaata cctaaaatcg ccggcatgac agtagacgta
     3241 tactgcatca gtactacagg aatccccaga aaatcagtag ctgctttgcc actgtctgaa
     3301 agtaaagagg tcagattcgg ttcaatcagt gctgcagcaa tgacagccgc aatatatcca
     3361 ttcactttaa acgttttggc ggcagaaaaa gcaagaaaga ttggcagaaa ataaaagacg
     3421 gcattcgacg cagcagacaa aatatgataa gttccgcttg tttcactaag ccagccaatc
     3481 gtagtcgcta aaacaaccag accttttaat ataccagaac cggcaaacag cggaatgatc
     3541 ggcgtaaaga tttccgatat caaaccaaat agtttttcga tcggatttag cttttcttta
     3601 ggagctgaat gatcgatttg acgcgttaat tccttgtaag caggagccaa tccctgatcc
     3661 atgattattt ctgcatatct atcgagtaaa atgaaatact taatggaagg gatttgctgt
     3721 tttaattttt ctgcattggc tactggctgt tttttcaatt tgatacgaag ccgagtcgca
     3781 catggaagga cagaatcaat attgtctttt cctcccaact gttcaatcag catatgaatc
     3841 tgctcggaca gtaccatctg ttcaggattc attgtcgttt ccattagaag accactccac
     3901 tcactaatat aatattggcg taaggtgtca tttcgcctgt acgaataaat gcatgacagt
     3961 tattcaactc ttttttcatt tcttcatgtg ggataaagct aatcggtgta tctggtaaca
     4021 ataatttgat tttttccaat atttccgggt tcattgtctt tatttcttcc gccaattcaa
     4081 tcgattgtac ctcaagttct tctaaaacgt tttctaaaac agataaaaag cttggaagac
     4141 cgtttgagac agccaaatct attttttcac taccaaaggg gacaggcatg cctgcatccc
     4201 cgatacttaa tttatcaaag tgccccattt gtgcgattac tcgtgaaata tctgaattga
     4261 ttacttttcc ttttttcatg tttgtttctt cctctcattg ttaattttag actgctgatt
     4321 gttctaaagc ttcgcggtaa gggatagaag gttgcgcacc ataagactgc acagcaacag
     4381 aagaggctag atttccataa aggatcgctt ctttcaagtt actaaggtct ggctgaagtg
     4441 tgctgcttaa tgcgccaata aatgtatcac ctgcggctgt tgtgtcaacg gcatccactt
     4501 taaaagcagg gacgataccg tgttcttttt ctgtatgata gaaagcgccg gcactgccta
     4561 gtgtaatgat tactgttcca atacctaatt catggagttt ttcggctgct gcgaccaaac
     4621 tgttatgatc tgtcactctg attcctgtaa tgatttctgt ttctgtttca tttggtataa
     4681 tgatatctgt tttttcaagt agttcagtag ggatcgtttc acgagctggt gcaggattca
     4741 ggatcgttgt ttttcctgcg tcttttgcaa tagaaaaagc taggatcgtc gcatctaagc
     4801 tactttcaaa ctgagcaata ataaagtcac tgtttgtaat cagttgcttg ttttttagga
     4861 cttcttgttc atggaaagca ttatttgcac ctgcatggat caagatacta ttttctcctg
     4921 ctgcgtctac cataatcatt gcttgtccgg ttgtggcgcc ttggatttca gctatcccag
     4981 atgtatcgat gttttctttt gtcagtagat ctaataactg ttgtccttcg ctgtcagccc
     5041 caacgcctcc aataaaagat gtccgtgcgc ctgaacgttt ggctgccact gcttgattgg
     5101 cacctttacc tccgccagcg tgaaaaatct catgcgcatg cattgtttcg cctggcttgg
     5161 gcatgttggt taaacgaagg gtagtgtcca tattaatact tccaattact gtaaccgtgt
     5221 tcattttaca aacctccaac tatctcattt attttgatgg gaaaaattat tttttaaaac
     5281 gttttagtaa aacgttttaa tagttcgata aaaatatagc acaccttgaa agctatttca
     5341 agggtgcagt tgaaaatctt ttttctaatc gtacaggtaa tcttttttct tcccattctt
     5401 tttctgggaa ttggatccga tctaacaata atttggcaga tgtttgtccc aattcgaaga
     5461 tcggttgtgc gatcgttgtc agtttcggct tgatatactc gcacatatct atattatcat
     5521 agccaataat gctgtagtct tcaggaatgc tttttccaga ttcctctaat ccgcgatata
     5581 atccaaaagc taattcatca tttaaagcaa acacaccagt tgcagcagaa tcaagaagtt
     5641 ctgctgtgat ttggtagcca ccttgttttg agaactgtgt aggtaagagg atcagttggt
     5701 cgtgagagat ttggtaaaca tcaagagcag atttaaaccc ctcaatccga gcgtggacat
     5761 tttccggcgg attttcagga tagacaaggg cgatcgtttg atgacctaga ctaagcaagt
     5821 gcatgcccgc taggtaacca ccgcgaaaat cgtctgttcg tacggcatca ctaaatcctt
     5881 cagatttttt ctgatccaaa acaatgaagg gccggccttg ttttttcaaa ttttcgttga
     5941 ttgcatctgt agagacagca gaagtcgcga taatgaatcc atccacacct cgacgtgtga
     6001 gctcggctag atattcgatt tctttttgat gatcagaatc agcattacat aatatcgtga
     6061 cgaaattctg cttatacaag atatcctcaa ttcctcgcat cagtgtactg aagaatggat
     6121 tcgtgatatc aggaacgagt acaccaattg ttttcgtttc cttggtaatc atttgtctag
     6181 caaaatagtc aggctgatag cctaattctt ctttggcagc taaaactttc tgaacagttt
     6241 tcggactgaa tttctccgta tttccattta atatcaagga gacagttgtg attgaaacgc
     6301 cggaaagttt agcgacttct ttgattgtga tctttttttt caccatgttc atactcctat
     6361 ctaaatcctg tggttatttt cccatgaaat caaaaagaag taaatgaaaa tcacgtgtgc
     6421 cagtacttat ttgctttgtt ggatagcttc gattatttgt ttcgttgagc gtactcgtgc
     6481 agttttcgga aatatctttt ttatgaacaa ttgatgggat tctttgtcac gatcactgca
     6541 agcatcttca gcaagtacaa catgataccc atgttggaag gcatctaatg cagtagcata
     6601 tacaccgttt gttgtcgcta caccgcttaa aacgatagtt tcgattccac gccggcgaag
     6661 ttgaagatca agagaagtac caaaaaaggc acttggattg tattttgtga tagtcaacat
     6721 attgtttgta tctttcaagg aatccttcaa caacaagtca gtgaattctg ccggagcaga
     6781 caaagcagat attcctccag catctgtctg atgacttaga taagagaaag tagtgatgtc
     6841 tacattcact aaaactttca aggcagcggt acgtttcaat gtttttgcta acaaatcatt
     6901 gtttgtcaga atagattgtg cagtgtgtgg agagagtgta ccgttattta cgatcccttt
     6961 ttgcatgtcg atcgcgacaa aagcagtttt tgataaatca aaaatcatat tttcctttaa
     7021 atcattcatg atgttccttc tttcaaataa caatgttttt tatgtaagta aatcataaat
     7081 cgtttatttg tcaactaaat aaaggattcc tttctttagt ctagagaaat tcagtggtaa
     7141 aataaataag tatgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa
     7201 tggaggaatc agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg
     7261 agaaacgacc attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt
     7321 gattatactt ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat
     7381 ggatacacct gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga
     7441 taaacagctt actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct
     7501 cgttcctaat ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc
     7561 gcttgatcct gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc
     7621 gtcccaatta tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa
     7681 tcccaaactt cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca
     7741 agtattgaaa ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac
     7801 acataattct gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt
     7861 aaggtctgtt gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga
     7921 ttttatgaaa acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg
     7981 acgattcatt gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa
     8041 aactgctgga cctgtcatgc aaaaaacgat ggaccactat gttggtacag caggactttc
     8101 tgatttgcaa atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa
     8161 gatcccagat gcaaaagtag aaacaggaaa acagatctat tattccaata ctggtaaaaa
     8221 cgaagtgatt caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac
     8281 tgatggaaaa ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga
     8341 agggtataaa atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta
     8401 taccatcacg ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc
     8461 gaacgtcgga aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac
     8521 agatatttat tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag
     8581 caaagcttac aaagataaaa tggaacacaa tcaagagaag gcagaaaagt atttacaaga
     8641 tcgccctgaa gaacgcttag aagagctgaa aaaatcggca aacgaagaat tagaaccagc
     8701 acagcaaaaa ataacagaag gcaaagcaca aatagcacag ggaagaacac agttagaaga
     8761 tgctaaaaaa caattagcgc aacagtcagc agctatccag cagcttcctg aagcgcaacg
     8821 aacaatcgct gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca
     8881 attagttgag aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga
     8941 aaaaattgaa aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg
     9001 ttttcaagaa tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt
     9061 tttctttttc tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga
     9121 aaaccgcagg gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa
     9181 aaaatatgca atctatgcaa gtctagcctc agggataggc attgttttag gaacgatatt
     9241 aggaacgaat cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg
     9301 gagtgcgctt attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat
     9361 tgccgcattt ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc
     9421 attgcttcaa ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc
     9481 gctgtggtca cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa
     9541 gtcaagaatg cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg
     9601 cgtgggattg aaagattctc taagttctgt ctcagctaaa caatttggac cgatcattga
     9661 ctatcaagca atcgttacat tggattcatc cactgaagat agtcgtcaaa aagcagcgga
     9721 tatgctgcag aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga
     9781 attgagaaaa aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc
     9841 tgatttggat cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa
     9901 aacaggaatc gctattacgc aaaaagcagc agaactattt gacttatcta caggagatca
     9961 tatttcgctt tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa
    10021 aaactatcta ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca
    10081 atcgatgatg gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga
    10141 aatgctttcc gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa
    10201 acaaatcgaa acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt
    10261 cgtattatca ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc
    10321 cgagcgtgta cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac
    10381 gatgtacatt gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg
    10441 tgtaggatat atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt
    10501 tccattagtg atcacatggt ggtcttatgt cttatcagca ggattaacta tcgtatttac
    10561 ggttattgtg atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt
    10621 gaaatcgaat gaataaaaac agaggttgtg aaatcagcgt tttgagctaa taacgagggt
    10681 cagctgctaa ttgaacaccg tgaatcagag gttgtgaaaa agctgtcctg catcgagcaa
    10741 aaggaatact caaataaaat tagctcctca tgttttacat ttgagaagac tgattgccgt
    10801 agataaaagc ttttgagcac catttataga agaaacaaga atattttgct attttaaaca
    10861 agaggataga caaatacatg tctgatctct tgttttttat tgggcaacag acctcttaga
    10921 atgtataaag ataaatttta caaacgcttt ctgttcagtt ataataataa atgataactt
    10981 gtatatataa gttgcggtag gtaataaatc agttgaatgg aggtaaatat ccatgacatt
    11041 taaagacaaa gtcatttacc aaatctatcc caaatcttac aaagacagta atggtgatgg
    11101 aattggagat ttaaaaggaa tcaaagaaaa actcccgtat ctgaatgatc taggcatcga
    11161 catgatttgg ctaaacccta tttatccaag ccctcaaaaa gacaacggtt atgatatctc
    11221 tgattacaca gccatcgatc ctatctttgg tacgatggag gaattcgaac agctaatagc
    11281 cgaagcaaag aaataccgga tagaaatcat gctcgatatg gtgctgaatc acgtttcgac
    11341 agaacatgaa tggttcaaaa aagcactagc aggggaccag cattatcagg acttcttcat
    11401 tttaagagaa gagccaacgg attgggtatc aaaatttggt ggaagtgctt ggtcgccatt
    11461 tggagatacg gggaaatatt atttgcactt atatgatcgg acacaagctg acttgaactg
    11521 gcggaaccaa gcagtaagag aggaactatt caaagttgtt cgtttttgga tggaaaaagg
    11581 ggtaaaagga ttccgtttcg atgttatcaa tgttatcggt aaagacgaac aattgaaaaa
    11641 taacaaagaa aatgatggca aacctgaata tacggacaaa ccaatcaccc atacgtatct
    11701 aaaagaattg aaccaagcaa cgtttgggac ggattccact atcatcacag tcggtgaaat
    11761 gagctctacg acgatcgaaa attgtatctt gtatacagaa cctagtagag aagaattatc
    11821 aatggtcttt aatttccatc atttgaaagt cgattatgaa aatgggaata aatggtctac
    11881 tcctccattt gattttgcag aattaaagcg actatttcat acatggggag aaaagatgag
    11941 tgagggtaac ggctggaatg ctctattttt taataatcat gatcagccac gtgcgctcaa
    12001 tcgatttgta gctatcgatc agtatcgaaa acaaggagca gagatgctag caaccatgat
    12061 ccatttgaac cgtgggacgc cctatattta tatgggagaa gaaatcggca tgatcgaccc
    12121 agactattca tcgatttccg actatattga cgtagaaagt ttgaatgctt ataagttact
    12181 ccttgaacaa ggattcacag aaaaagaagc gtttcgtcgg atcaaagcaa aatctcgcga
    12241 taactctcga acacccatgc aatggtcaga cacagaacaa gcaggattta ctacagggaa
    12301 accttggtta aaagttggag gcaagctaga agagattaat gtagaaaaag aactatcttc
    12361 tgaagattct attttgtcct attacaagaa attgattcgg ctgagaaaaa catatccaat
    12421 cgttgcacaa ggagattatc atgcttatga agcaaatcat ccggaagttt atggctttct
    12481 tcgccaattt gaaggacagc agctgcttgt attaacaaat ttctatgata aagatacaag
    12541 gatcaccatc ccagaaggat tcacagaagc caatattctt atcgataatt attccgatac
    12601 tgttcttcat caaagtctgg agctaaaacc ataccaggca attgctttgc tgaaaaatta
    12661 aaacaaaaac acaaaacgtc gttcctacga gctattctcg taagatcgac gttttgtgtt
    12721 ttatttaaaa taatcttctt cagaaaatga agagttttca tactctcctt tatcgccata
    12781 aaatttattg tagcgttgtt tgaatttacg gaaaataaaa gtaacgagta atttgactaa
    12841 cgtatagata ggaataccaa aaataacgcc cacaattccc attagatcac ccatgacaag
    12901 taaaacgatt aagatcgtaa tcggatggat ctgtaaacga tcacccatta ctcgaggaat
    12961 caccaagtca ccgtggagaa gttgtacggc aaaccagaca atgacaaatt tgacagccat
    13021 aaaagtagag tcttggaatg caatgatcaa acctggaaag aaggcgataa acggcccaat
    13081 atatggaatg atacataaca acccagcaga aatagctaaa acactagcaa attctaatcc
    13141 gatcagtaag aaacaaaccc agtagactgc tccaaggata aatgaagcaa tgatttgccc
    13201 ctttagaaat gaacccaatt gttgattagc aatctttgtc aaatttttaa aatctgtacg
    13261 aaatgctggt gggacaatcg ctaaaactga ctgataaaat ttttgaggat ctctcaaaag
    13321 aaaaaaagcg acaattggac cagtaaataa agtaataaaa atagctgtaa cagttgaaaa
    13381 aatgttgctg atccgttgtg cgccactttc ccaataattt ccaataaatc cagctatatc
    13441 agacgtcacg tcgtcaatag aagcgaaaaa ttgattaaat gaatcggcaa aaggtgtttt
    13501 ctctaaaaat tgtcggagac tctcttgaaa atcttgaaac aaatctggca aactactgat
    13561 caatgtcttt gcctgttctt caagaaaagg aacaagccat acgcttccaa gccccaataa
    13621 aaataaaata atcacataaa cgataatgac tgacaagttc ctcgaaaggt gcttgctcaa
    13681 acgtttgatg actggttcca aaagataata caagatcagt gcaaacaata atgggggcaa
    13741 gatagtagcg ataatgattc cgacaggctt gaatataaac gagatctgat ggaaaaaata
    13801 aatgatcagc gcaagtaaga taactattcc taaaacatag taagaggttt ttcctcctaa
    13861 aaagcggatc aaacgattcg ttgtatctgt ttcttttttc actctttttc ctcctttatc
    13921 tataacttca ttatagacaa aagcgggtat aaaaggaaaa tgatagaggt tgattgcaaa
    13981 aatatcgtca atcattcata taaactttct catcaattaa aataagaaaa cgcttgacag
    14041 ttcttttaac catatgataa attaaatcct gttgctaaaa cgtaactatt acgttttgta
    14101 aaaggcgaat cggaacattc aaatgaaaga agatgagaag aggagtgtca taaatgaaac
    14161 gattgatagg tatattggcc atgctggttt tagcaggtat gttaactgct tgcggcgggg
    14221 caagtgggaa agccgaggac agtaaagaaa aattgagcgt gatgacgacc ttttatccta
    14281 tgtatgattt tacaaaagca atcgtcgggg atgaaggaga agtagagtta ttgattccag
    14341 cagggactga ttcccacgat tatgaacctt ctgctaaaga catggcaaag atccaagata
    14401 cagatatctt tgtttataat gatgaaaaca tggaaacatg ggtccccgca atccaaaaaa
    14461 cattacaaga aggcaatgtc catacgataa aagcgacaga aggtatgctt ttacttccgg
    14521 gaagtgaaga aggacatgat catgaccatg aacacgggga agaaggccat acacatgagc
    14581 tagacccaca tgtatggcta gctccaagtt tagcaatcaa gcaggtagca aacatacgtg
    14641 atcagctgat tgaagcttac ccagaaaaac aggaagtatg gacaaaaaat gcagcagcct
    14701 ataccgagaa acttcaagca ctccatcagc tttatcaaga aacctttaag caagcaaaac
    14761 aaagatcttt tgtcacgcaa catgctgcat tcaactatct ggcattagaa tatggattga
    14821 atcaagtatc gattgctggt ctttcttcta gtgaagaacc gtctgcggcg agaattgctg
    14881 aactgaaaca ctttgttaaa gaacatggaa tcaactatat ttattttgaa gaaaacgcca
    14941 aagatagtat tgccagaacg ttagcaaacg aagcaggtgt atctttagaa gtattgaatc
    15001 ctttggaagg attgacgaat gaacaaatag aaaatggaga aaactatctt tctatcatgg
    15061 aagcaaacct cgaagcgttg aaaaaaacga cagagacaga aaacccgcta gaagatactt
    15121 tgacccccaa aaaagaaaag agcgtctaca acggttattt tgaagacgag gatgtacaag
    15181 atcgctctct ttcagattgg gcaggaactt ggcaaacagt agatacgtat gtagaagatg
    15241 ggacttttga tcctgttttt gaatataaag aaaaattgaa tcaggataag acagcacaag
    15301 aatataaaga atattatacg aagggctatc aaacagatat tgcttcaatc aagatcagtg
    15361 agaaagagat ggcatttacg tttaaggatg gaacaacgaa acgttcaaat tatcgttatg
    15421 tagggaaaga aatcttgacc tacgaggcag gaaaccgtgg cgtaaggtat ctattcgaag
    15481 cagaagataa ggaaagtggc gcttttagat atattcaatt cagtgatcac acgattgcac
    15541 cggctgactc cgaacatttt catttatatg caggaaatga aagtcaagaa gcattgctga
    15601 aagaaatgga gaattggcca acattttatc cagatacaat ggatggacgt gaaattgcac
    15661 aggaaatgct tttgcactga taggcaaaaa agaaccgaag ggtttggatc ggctagtcat
    15721 ttagtcggtc caaactattc ggttcttttt atgaaatcaa tttctttaat ccacggatag
    15781 aggctgggat ggtctcgccg tttgccaacg tgacttctct ggttttttta ttaatcgacc
    15841 gcacattttg tgtattgata acataggatt tatgacaacg gataaaattc cgatgcattt
    15901 tctcgatttc tttgatcttc tcatagaatt gtaattgggc atgagtcaaa tggacttcca
    15961 gtttatgtgg tgctcctagc gaagtagaaa aatattggat gtctttgatc ggtaaaaatt
    16021 tgatctcatc attaaactct attttgaaga tatctttttg gatctgggac atttgaaaat
    16081 cttcgaaaat tttgctcagg atatgctcga cattttcttt taaatcataa agatcttctt
    16141 tgacgatata atcagtcggt tcgatgttgc tttttaagat tttcatcgac atttccgtat
    16201 gggaagtcac atagattatt tttcctaagg gatctaattc acggatcaat ttaccgatcg
    16261 ctacaccatc catttcactg tcttctagtt cgatatctaa aaagtaaata ccaaaagaag
    16321 aagttctgat cttggctgca ttgagaagtt cttccggatc agaggtagaa atatggacat
    16381 aactgtctaa gttttcaatc atgattctat ttttgatcac cgttgataaa acttctaatt
    16441 gttttggatc gtcttcacaa atataaatgg gaatcatatc attactcctt tattttattt
    16501 gtatataaat cgtttgagaa aaacgctggt tttcaattga tgtttcaagg aaaagataag
    16561 gattggtctt tgtcaattca tccaagataa acaagccaag gccttcgttt tttggatttg
    16621 tttttgttga gaaccctttt tgtttcaact ggtttaacgg caatgtattt gttgttgtat
    16681 tgatcacacg aatcatcacg gaatgattct tcttgagtat ggtcaattcg atttttttct
    16741 tctttgcagc actagctcct tcaatcgcat tgtccaagat aataccaagc atacgtacaa
    16801 ggtttaccgt atgtttcgta tccagttcga ttggctcagg aaaatgaagc tggacgacca
    16861 accctttttc ctgtgccatc atgagtttta atgacagtaa actacggatc tcaggaactt
    16921 tcatattatc caacatactt agattggccg gaaaaaggtt catcatctgg cgtgtaggta
    16981 atatcgtttg agcataataa gaccgtaatc cttctaagtc gccttctgaa atatagctgt
    17041 gaagagaaaa aagcagattt tggtaatcat gtttgaattc tctcaagtct tgatagtttt
    17101 tttctagatc tttgatataa tcctgttgca tcctgacttg ttgctctaat aactgatcag
    17161 ctaatttctt attagagatt ttccaataat aaaccaagat gatcaggcca acacacagat
    17221 atagaatgaa aaaactcgta ttcaaagcta agacatcagg tgtttcacca gaaaaacggg
    17281 tataaaaaat aatgatatag tatgtaaata atatcaatgt cccgatcgta ccgatcatac
    17341 ggcggtccac agtgtgaaac caagtctcta acgatttttt aaaacaaaaa gctaataaag
    17401 cagataaaaa agcggataag gcaatgtgaa aatactgcaa tgaatctcct ggttcaataa
    17461 ccgaagattt caaaacaaaa aaatcgccga tgcttgttaa gtgatctcct aaaagcgacg
    17521 tcaataaccc aaaaggaagc gcgtaaacca attgttgacg cgaagtcgaa aagaagaaaa
    17581 aagtaagcat cagcattcct atagcaatta gagcagtaaa aatccctaaa atcgaataga
    17641 cccatccaat caaaatacaa gaaatcagaa tgactcccgc aaacagatat ttgtatcgga
    17701 tgtgatggtc aatcaataag atacaaattg tgtaaatcaa atattgcaac gctatggacc
    17761 ataaaaacat aaagtacagc tcccattgat ttttaccaaa ttatagcaca attagcgtat
    17821 tattttttta atttttcagg gattttgaat tcagaactca taccaaagca gcagccagat
    17881 acaaaaaagt cagataagtt agttaattgt ttaatgattg tttttttcat gaaagattcc
    17941 tccaaaattc atcaagtagt ttgtaatagg aagcaacgta gctatttcta aaacaatccc
    18001 aagtagcaaa taggtagaaa agtaagaagc tgagaaaaat aaagtaatga gagaaaaaat
    18061 tagaaacatg ctgatcgcct tctttaataa tgggggacgt ttctcgggtt caatgggatt
    18121 gattgctgta cctcttgatc catagcgaag cagtaacaaa aagcagctga ttaacaaaaa
    18181 gaccatcatt gggaaggaga tagtcaattg cagatgtttc atcaccaagg gaacgcccca
    18241 taaataaagt agtgtccaca gcagacaaac gaattcagag tcggaatgca atccataagc
    18301 atatctgcgg atgcatatat aagaaagaaa ggtgattcct gtttccgccc atgagcctgt
    18361 caccagagaa aagactagaa cgaccgctag ttttccaaga ttattcaata aaacttctaa
    18421 ggcaaatttt acttggacat acaccatatc ttcttccgat ttgtctccgc tgaataaggc
    18481 ttctaataat ttgttcacaa ctttatcttt catctcatac gtacctctac cacaaatttt
    18541 atgctaaaaa aaataaaaaa cgtcttttgt ttcataaaaa gtggttttga catcaaaacc
    18601 gtcatgattt cctaaaaaaa tcttcgtttt ccaagaacct taccaaaaaa agtgacagtt
    18661 ttgatacgaa aagtactttt tatgacaagt ttgtgctttt tcgagtgatt tatgttaaaa
    18721 aaattactga ccttataaaa ggtgatggag ggattcttat ggaaaatgaa caattgtttg
    18781 aagtcggcga aacatatgca tttaaatctg atttatttga atcaccaata aaaggaaaaa
    18841 tagaaaaaat ctatgaaaat agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca
    18901 atgataccgc tcataatctg cactggcagt tagttgtacg caaatcaagt acaatagaag
    18961 aataaaaaca gataaaatgt tgagagcata aagaggttgt gagtctccgt ttagctctga
    19021 gttacaagga ataatgttaa aaaacagctt ttcatgtttt atgaatattg ccacttgtga
    19081 ccgaggtgtt ggcaggagaa tactgtttat ttgaaaaaag ggctgcgaca agacttttgt
    19141 cacagccttt attttcatga ataggagtta cttttggcta cttttagaga agtagctttt
    19201 aaggagcaga taaagtcaag gcttttattt ctataaatga agtagtaaaa tgaagaacag
    19261 attttattac aggaaggatg ccgataattg tgatcattgt tgcaggaacg atcggtgcag
    19321 ggaaaagcac actgactgaa atgcttgccc aagatttaga aacaaaacct ttttatgaga
    19381 acgtggaaga taatgaagta ttgccgctat tttattctaa tccagaaaag tatacttttt
    19441 tattacagat tttctttttg aacaaacgct ttttggcaat caaagatgct ttcagccatg
    19501 atgacaatgt actagaccgc tccatctacg aagatagtat gctgtttcat ttgaatgcag
    19561 atttagggcg tgtttctgaa gtagaagtaa agcagtatga aggtctttta gaaacgatgc
    19621 tgaaggagtt agaagaaatt tcgccacaaa agaaaccaga tctactggtt tatattcgtg
    19681 tatcttttga aactatgtta gcgagaatca aaaaaagagg ccgggaatat gaacagctag
    19741 aacaagatcc tgaactctat tcctactata aagaactcaa tcgacgatac gaagagtggt
    19801 atgaacagtt tgatatatgt cccaaaatag tgatcgatgg ggacaaatat gatttcgtag
    19861 ccgatccggc atgtggagaa caaatcgtac aagaaatcaa gatgcgggca aagaaaatga
    19921 cagaagaggc agatgcccag tcgatccgct acactacaaa taacccgaaa gcaaagggaa
    19981 tctttacaac taaataatat aaaaactaag caaattgctc actcgcagat atttctctgt
    20041 gagcagcatc ttgcttagtt tttttgattc attgagatca aatagtgaac cgattcgtat
    20101 gataaaattg ccataaatga aatgtctgag tgagggccat gatcaaaaat aaaatggaaa
    20161 cgatcaaaat cgaatgggcg ccaaacagat gatgacagaa aacaaggaca atagctcctg
    20221 cgataaaggc aagaacgaca cttagatagt ggaaaaatcg atcaaaatct gctttttctt
    20281 tagaaataca ataatcatat aagttcgttg ctaccccttt taaatttcca gttgtaaata
    20341 aattagtgta ggcacgcccg ttgattttat caaaagctac ccactggatc gatgcagtaa
    20401 aagcaatcaa aatcgttact aatgcgggat gctcatggac gggtgtcaaa ctaacaaaga
    20461 aaaaaatcac tgcttcataa tatagaacaa acaagcgcca gaaatgtttt tctttttttc
    20521 taaaataatc aattagatac tttgttagaa gaatccctaa gaaaaagaaa agggtagaca
    20581 atactttttt accaacactt agccattctc cgtcaaatgc ttggatgatc gatagaatga
    20641 tattgccagt ttgagcagag gcaaaagcac catattggat ataagtataa ctgtccatgg
    20701 ctcctccgat aaatgtcagc aaaagtccta ttgtacgccc ctcgtgaaag gaagtctgca
    20761 tttttttcat caccttttat gaatattttt gtcttcctta tcttagcata aacgattgaa
    20821 aaaaaggaaa aattttcaga aaactaaaat catatcgctt cccattttca tttttagaaa
    20881 ggtctgttag tataaagaaa aaatagacaa cgaaacttta aataaccaac ttgaaataac
    20941 caacttgaaa taaacaaatt caaagaagaa agatgggaag gaaatcaatc agttgaatga
    21001 aaaagaaatt ctccgattac aaaaagaatt gaaacgctgg gagaacaagt ataaaaagct
    21061 tcaacaagtc tttcggctac aagaagaaat cattgctacc tatgaagcgg cttatggcga
    21121 agcacccgga cttattgagg aagaagtaca agtaaaagaa agtgaaggaa acagctcttt
    21181 ctttaaaatg atggagaaac gttcctataa tcgcttcaat caagaacaaa aagcagctat
    21241 cacatatgat atgaagaaac atcttcgaat catagcagga gctgggagcg gcaaaacgca
    21301 aacaatctgt gcaaaagctg tttatctgat gacgcaaaaa caagtagacg aagaacgcat
    21361 actaatgatc acttttacaa ggaacgctgc aaatgaacta aaaaaacgag tagataattt
    21421 cagccagaga aaaaccgctg tccatatcgg aacattccat agtatctttt ttaggatata
    21481 caatgaaatt tgtcgaaaat ttcctgaagt agcaatgcaa ggaatacaag gagacttttc
    21541 aaaggatact gcacaaaaag tgaatgctgt tttgcaacag ctgatacgta aatataatct
    21601 ttatatattt gatcaatatg gagaaaaaac gattgcttct cggttagact attggcagaa
    21661 tatgaacctt tcagtagaag aaatggttca gttagttaaa gaaaaatatg attccattga
    21721 taagaatgca cgacagccga tatcagaacg actgtatgga ttgctcacgg aactccaaga
    21781 acaaaaaaga agccagcaat tgctagagtt caatgatgta ctccaaaatc tgaaaagcgc
    21841 tttggagaat gaggagatcc agcattatat cggccaaaaa tatgattatc tattcattga
    21901 tgaatttcaa gatactaatc cacttcaatg ggaaatcgtg aaacggatga caaaggaaaa
    21961 caggatcaag ttgattgttg ttggagatga tgatcagagt atctatggat tcagaggatc
    22021 agagccagca tacatcaaga actttgaaaa agaatatcct accaaaactc ttttcttatt
    22081 aactaattat cgttctcggg cagctattgt ccaaggagca aatagattga tcagctataa
    22141 taaaaatgat cggataccaa aggcgatgat tccagcacaa aaagaagcag gtgttatgga
    22201 agcctatttg ttttctgata ctaaagcaga aagtcagtgg ctaatcaaac aaattcagac
    22261 atttattcaa aaaaatggga aatataagga atcaatcata ttataccgat cagcttcaca
    22321 aacgcagcag cttgtccaat ctctgctgaa aacgaatatt ccttttgtac tggaagcaga
    22381 tagtccatat gaaggtatct ttggtatcaa gtctttccaa catttctatc aaaaaattgt
    22441 tcattggcaa acagcactga atctgcaaaa gaaaaatcag gcctaccagc aattgctccg
    22501 gcagctgatg gcagactgct acctgaaaaa aagtgaatgc gatcaatact tttctcctaa
    22561 atatcaaaat atagccgttg cagattatat tttgtcgata agccccaatt taaaatcaaa
    22621 atctgcagaa atccgagagt ttgaggaagc gttgcgtaaa acagaccagc atcaagaaat
    22681 ctattcgctt gttcaaagct atcttcatct gccacgtata gctaaggaaa tcgaccagag
    22741 tgatcaagaa tggatacgag aagaagtaaa gcagcatgct actttcagaa gactccaagc
    22801 cttatcgcaa gaaacccaag cgacagctaa agaattaaaa acccgcttga ttgcttacag
    22861 acaaggaaaa cttgatgcac tatgtatcca gagcattcac aaaagtaaag gtcttagtta
    22921 ccgaaatgtc tttttgattg gttgtaacga aggaagtttg ccttataacg gagcgacaga
    22981 aaagaaagta atcgacttta atgaaataaa agcagaacca gtgacgacga tagaagaaga
    23041 acgaagacta ttttatgttg cgatgactag agcaagaaat cgtctgtatc tatgtgtacc
    23101 tcaaatgaaa aattcaagaa aattgaaagt atcgagattt atcaaagaaa ccgggagtcg
    23161 tgtgaaaaaa ggaaagtgat agaagagagg gtgtgacaga agtggtcagt ttcaagaaag
    23221 aagaaggaat gtacgaaaat tgcttctcaa atttttgtga aatttcagct tattttcgaa
    23281 gaagctattt ctggaacacc gtttattcgg aaaaaggagg tgtgacaaga attttgtcac
    23341 acctccctta tttattttga aaatgagaat actattatca aaatagagaa tatatagaat
    23401 aattctcatt attcaaacgt aaataatcag tt
//
LOCUS       DAJSMK010000037        23067 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.038, whole genome shotgun sequence.
ACCESSION   DAJSMK010000037 DAJSMK010000000
VERSION     DAJSMK010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.038"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            103..273
                     /locus_tag="ON488_001443"
     CDS             103..273
                     /locus_tag="ON488_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231644.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            493..1200
                     /locus_tag="ON488_001444"
     CDS             493..1200
                     /locus_tag="ON488_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3231645.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1259..1903)
                     /locus_tag="ON488_001445"
     CDS             complement(1259..1903)
                     /locus_tag="ON488_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HCR3231646.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            2030..2317
                     /locus_tag="ON488_001446"
     CDS             2030..2317
                     /locus_tag="ON488_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231647.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2425..2745
                     /locus_tag="ON488_001447"
     CDS             2425..2745
                     /locus_tag="ON488_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3231648.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2826..4139
                     /locus_tag="ON488_001448"
     CDS             2826..4139
                     /locus_tag="ON488_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HCR3231649.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            4136..4855
                     /locus_tag="ON488_001449"
     CDS             4136..4855
                     /locus_tag="ON488_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HCR3231650.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            4983..5534
                     /gene="raiA"
                     /locus_tag="ON488_001450"
     CDS             4983..5534
                     /gene="raiA"
                     /locus_tag="ON488_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HCR3231651.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5756..8290
                     /gene="secA"
                     /locus_tag="ON488_001451"
     CDS             5756..8290
                     /gene="secA"
                     /locus_tag="ON488_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HCR3231652.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            8416..9517
                     /gene="prfB"
                     /locus_tag="ON488_001452"
     CDS             join(8416..8487,8489..9517)
                     /gene="prfB"
                     /locus_tag="ON488_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HCR3231653.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9622..10308
                     /gene="ftsE"
                     /locus_tag="ON488_001453"
     CDS             9622..10308
                     /gene="ftsE"
                     /locus_tag="ON488_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HCR3231654.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10292..11185
                     /locus_tag="ON488_001454"
     CDS             10292..11185
                     /locus_tag="ON488_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231655.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            11337..12785
                     /gene="cls"
                     /locus_tag="ON488_001455"
     CDS             11337..12785
                     /gene="cls"
                     /locus_tag="ON488_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCR3231656.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            13122..13979
                     /locus_tag="ON488_001456"
     CDS             13122..13979
                     /locus_tag="ON488_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HCR3231657.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISIENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            14094..15014
                     /gene="pstC"
                     /locus_tag="ON488_001457"
     CDS             14094..15014
                     /gene="pstC"
                     /locus_tag="ON488_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HCR3231658.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            15014..15898
                     /gene="pstA"
                     /locus_tag="ON488_001458"
     CDS             15014..15898
                     /gene="pstA"
                     /locus_tag="ON488_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HCR3231659.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15913..16719
                     /gene="pstB"
                     /locus_tag="ON488_001459"
     CDS             15913..16719
                     /gene="pstB"
                     /locus_tag="ON488_001459"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCR3231660.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16735..17493
                     /locus_tag="ON488_001460"
     CDS             16735..17493
                     /locus_tag="ON488_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HCR3231661.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17506..18183
                     /gene="phoU"
                     /locus_tag="ON488_001461"
     CDS             17506..18183
                     /gene="phoU"
                     /locus_tag="ON488_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HCR3231662.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18406..19437
                     /locus_tag="ON488_001462"
     CDS             18406..19437
                     /locus_tag="ON488_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCR3231663.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNSDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNKSILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            19434..20201
                     /locus_tag="ON488_001463"
     CDS             19434..20201
                     /locus_tag="ON488_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HCR3231664.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            20301..21869
                     /gene="liaX"
                     /locus_tag="ON488_001464"
     CDS             20301..21869
                     /gene="liaX"
                     /locus_tag="ON488_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HCR3231665.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            22045..22353
                     /locus_tag="ON488_001465"
     CDS             22045..22353
                     /locus_tag="ON488_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HCR3231666.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF
                     "
     gene            22353..22703
                     /locus_tag="ON488_001466"
     CDS             22353..22703
                     /locus_tag="ON488_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HCR3231667.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            22841..>23067
                     /locus_tag="ON488_001467"
     CDS             22841..>23067
                     /locus_tag="ON488_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231668.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAH"
BASE COUNT         7597 a         3973 c         4963 g         6534 t
ORIGIN      
        1 gttagttcga gagctctttt ttttgctttg ctaccttgtt ccttgaagat tctgctgaat
       61 taagatagag ttaagttaac tacaagaatt ggagggatcc acatgaaatg gaaagaaaaa
      121 gtagacgaag cagctgaaaa gttatatgat ttggtcaaat cagaaaaata caatattgaa
      181 gtgaatattc cgaaaaaagg cggaaaagcg gtccaggtaa aatcaaaacg cccaacgaat
      241 catacaaaaa aatggatggc taaaaaccgc taataataac aaaagatcca taagtcggca
      301 ttttcatcga ttttagggtc ttttgttatt ttctaggttg aacatatcta aaaaattgtt
      361 tctgacaata ggagtaggga gaacgatgtg tgtctaaatc ctctgttgat ggatagaaac
      421 ctttatcttt ttcagttgtg aatcaggtat ataccagtta taatagaaga aacgaaagga
      481 cgggtgtacg ttatgtcgaa tcaattacct gtatatatac agattcatga ccaattaaaa
      541 aatgaaatcg aacagggtat atggaaagtc ggagaccgtc ttccttcaga aagagaatta
      601 gcagtgaaat tcaatgtcag ccgtatgacg ttgagacaag caattcaaaa cttggcagat
      661 gaaggaatct tagaaagaaa gatcggttcg ggtacgtatg ttgcgcgaga aaaagtacaa
      721 gaaaaaatgt ctggtgcaac aagttttaca gaaattatgg aatcacaaaa tcgagtaccg
      781 tctagtcgga caatctctta tttcttgact tcgccaagct caagtgaaat ggaaaaacta
      841 aacttgagta aagatgacac gatcttgcga atggaacgta ttcgtttcgc agatgatgtc
      901 cctatttgtt ttgaagttgc cagtgttcca caaaagctga tcgatggcta cagcaaagca
      961 gagattactg aatcgttgta tcgcacgcta gaagaaaaag gcgggaaaaa gatcggtcca
     1021 gcgaatcaaa cgattactgc tgtgttggct tctgagaaaa ttgctgacta tttagaggta
     1081 aaacgaggag atgcagttct tcgtttgcgc cagatttctt attttgaaga cggtacgccg
     1141 tttgagtatg tgcgtacgca atacgtagga aatcgttttg agttttattt ggaaaaataa
     1201 aaaacaggtg atccctgatt ccttattaga aataaaagag aatcagaatc acctgttttt
     1261 atatatgatc agttatcagt tgctcgtgat aagaaacaga accctcttca aattggactt
     1321 gtccgttcag cagctcaatg atggattctt taaagtggtc agcacttttt tcatctacag
     1381 cacagatgac gctaacttga tcagtatatt ggatttcttt tataaaaaaa tgttggagtt
     1441 caagataatt ctgtaatttt cctagttgcg gatacgtgat catcacagag atctcctgtt
     1501 gcaaggtacc ttctacgatt ccaatgtcag acaatgcttg agagaccgca tgagtgtatg
     1561 ctcgtattaa tccgcctgtg ccgagtttcg ttcctccaaa atatcgagtg actactgcag
     1621 ctacattgat cagttgattt tttttgagga cttccaacat cggtacgccc gccgttccac
     1681 ttggttctcc atcatcgctg cttcgctgga tttcattttt ttctccaatg atgaaggcgc
     1741 tgcagttatg gttcgctttc caatgttctt tttttatttc ttgaatgaaa ctttttgctt
     1801 ggtcctctga ttctattcgt ctaagagaac agataaagcg tgattttttg atctcaatct
     1861 cactttgtcc attttctttt attgtacgat agcgctcgat catcttgtca cctctttttt
     1921 tcattttctt tattcagtat aaataaagtt ctaggttgtt tcaacactgt aacggttgcg
     1981 caattgctgt agtatgcgat aataaagaca aaggcaggtg gatctgggga tgcaggaacg
     2041 aatgaaaaag tacgatgcaa ttacgcatta tttgaagaac aatggcggct ctcaagtaac
     2101 gttgaccttt acccaatttg acgaactgct gtttcccagt aacggacttc ccaaaacagc
     2161 aagggaaagt acagattggt gggcaaatga ttataaacac cctgaaaaag gtgcctatgg
     2221 ctggataaat gcaggctatg aagtagttgt catcaatttg gacaaagaat atgtcgtgtt
     2281 caataaatta gtgaaatcta gttggctatt tgattaaata aaccgcgttt agaaaacgtt
     2341 gacaaatttc tttcttttta tataatagag taacagacgc gaagaaaacg tttgcatagt
     2401 ttgttttaaa aaggagagaa aagtatggct aaaaaaacaa tcatgcttgt atgttcggct
     2461 ggtatgagca caagtttact agtaacaaaa atgcaaaaag ctgctgaagc aaaaggaatc
     2521 gactcggata ttttcgctgt gtccgcttct gacgcagata acaaccttgc aaataaagac
     2581 gtggatgtgt tgttattagg cccacaagtt cgctttatga aagctgattt tgagaaacgt
     2641 ctggaaccaa aaggcattcc tttagatgtc atcaatatgg ctgattatgg tatgatgaat
     2701 ggcgaaaaag tgttagatca agcaatcacg ctcataggtg aataaataga acagtataac
     2761 tatcgaacaa gcgatccaaa aaatagatcg cttgtttttt cgtatatttt tttagggcga
     2821 agaatatgaa tcatttttgg ggtagaaggc ttctgacgag agatattgaa gcaatagact
     2881 gtgaggaggt aaatttacca aattatgaga agatcgcagc agtggaacgt ttgggcaact
     2941 ggattctttg tcatcgctgt ggaatgagga cgtccgtcat tgatggacag cttgcagatt
     3001 acggttattt ttgtacacat tgtctatatt tagggcgatg cgacactcaa caagatttat
     3061 atttgtttga tcagcctgaa gcaaaacctc gagaagtcgt ctttttttgg acaggacagc
     3121 ttactgaaaa acaaacggaa atctcaaaga gaatactttg ccattcagaa aaaagacatc
     3181 atcttatttg ggctgtaaca ggtgcaggga aaacagagat gctttatcct attttagtgg
     3241 aaactttaaa agctggagga agagtagcga tttgtacacc gcgagtcgat gtttgtaatg
     3301 aattgttttt acgctatcgt tatgtttttc cagaagaaaa aatcacgttg ctccatggga
     3361 atacagcaac ggcttatacc tttacttctt ttgttatctg tacgattcat cagctatacc
     3421 gtttttatcg gtcctttgat ttaatagtga tcgatgagat cgatgcgttt ccttataacg
     3481 gggatgcagg attagctcat gctgtgcaaa cagcgattaa accagacgga cgattcatct
     3541 acttaagtgc cacacctgat aaaaagttac taaaggaaat caagcagacg tttgacatcc
     3601 acaaacttgc tttacgcttt catcggcgtt tgcttcctga acccgtcttg gttttcatga
     3661 ataattggcg acaaaaatgc aagaacaaga agaagataaa atctttggtg cggatcattc
     3721 atcaattaat taaagaaaac catatccttt tattttgtcc aagtatcacg atgatgcatc
     3781 gtttgaaagc cacacttcaa gaggctcttc cgagatatga gatcacagat gtttcttcaa
     3841 gagacaatca gcgggcggaa aaagtccaga aaatgcgaga agcaaaatat gatatactgt
     3901 taaccacgat gatccttgaa cgtggagtca catttgaaag aatatccgtt atcgttttag
     3961 gagcggatca tccggttttt actaaatctt ctttggtaca aatcgcagga agagccgatc
     4021 gtaaagggcc ttatacgaac agtcaagtat actttttcta tgaagaaaaa actgcagcta
     4081 ttcgaaaagc ttgtcaggaa atcaaagaaa tgaatgaaga agggaagaag atgctgtgag
     4141 gtgcagttgc tgcagtaaag atatcttcca aaatttaaca ttcagcgaga ttattggtgt
     4201 ttcgaaatac agattacctc agacttgttc agtttgtcgc gcacaatttc atttattgga
     4261 aacaagaggc tgttctggct gtcaaaaacc aatccatttc aatctagaga gtacgaaaaa
     4321 gaaagtaaag tctattcccg tttactgcag tgactgtcaa gaatggaaga agaaatatcc
     4381 gacctatgat tttcagcacc gtgccttttt tgtgtacgat gaaaatatga aggcctggct
     4441 caatcaatac aagtttatgg gagatatccg actagcaggc acctttgcat ataaatggac
     4501 gcagataaaa aaagaatacc cgacatacat ctattgtcca atacctttat ctgaaaaaag
     4561 gcgaacagaa agaggattca atcaagtaag cgagatgttg aaagcagcaa gaattccttt
     4621 tcagatgcta ctcaaaagag agaagcatct gctggctcaa gcaaaaaaca cgcgaaagga
     4681 aagattggag atgcctcaac cttttgaact tgcagtcacc ttttctaaga tacaaaataa
     4741 aaaaatattg attattgatg atgtctatac aacaggacag actcttttcc acgcagcaga
     4801 ttgtttgcag gtcgcacagc cgaaaatcat ccgaaccatt tctttggcga gatgaattag
     4861 atgtggaaat ttgatagcga tttaatttgc aaataaccta gagttcgata taatagaatt
     4921 aagaagaggg aaagagtggt ccttctcctt cttgattgtg gtagacgaaa ggggtaattt
     4981 ttatgtttag atataatgta cgcggcgaaa atatcgaagt aactgaagcg attcgcgact
     5041 acgttgagaa aaaagtaggc aaactagaac gctatttcag tgacgcaccc gatgcaacgg
     5101 cgcatgtgaa cttaaaagtt tatacagaaa aaacagcaaa agtggaagta acgatcccat
     5161 taccttatct tgtattacgt gccgaagaaa cttctccaga tttatacgca agtatcgatt
     5221 tggttgttga taaattggaa cgccaaatcc gcaaattcaa aacaaaaatt aatcgtaaat
     5281 cccgtgaaac gggcatgaat actgcagatg ctgctgcttt attcaatgaa gaggacgaaa
     5341 acgaaaatga ttctgaatta gatatcgtac gtacgaaacg cctttcattg aaaccaatgg
     5401 atagtgaaga agcagtctta caaatgaaca tgctgggaca taacttcttt atttttgaag
     5461 atgcagaaac aaatggtaca agtatcgttt accgccgtaa agatggaaaa tacggactga
     5521 ttgaaacaga ctgatcagcc ttacttaaat aacaacgaaa acttgcagca gctactgaca
     5581 gctgccgcaa gtttttttga gtttcctcct cttttagatg aaatatgaat aaattatgaa
     5641 gttcttactt taatacgctt aagatatttc aattatctat aactaatgat aaaatgaaaa
     5701 gtaaagtcta catagtctgg ataatacaca gaaggaaaag gagattacac aacgcatggc
     5761 caatttgatt cgttcactta tcgaaaacga taagaaagaa ctaaaacgtt tagatagcat
     5821 tgcaaaaaaa gttgaagcat acgctgacca aatggcagca ttaactgatg aacaattaca
     5881 ggcaaaaact gctgaattca agggcagata ccaaaaagga gaaacattag atcaattact
     5941 tccggaagct tttgcagtcg tccgagaagc agcaaaacgt gtattggggt tatatccata
     6001 ccacgtacaa ttgatgggtg gaatcgtgct tcacgatgga aatatccctg aaatgcgtac
     6061 tggtgaaggt aaaaccttga ccgcaacgat gccagtatat ctaaatgctc tgactggcga
     6121 aggggtacac gtagttaccg tcaatgaata tttagcaacc cgtgactcga cggaaatggg
     6181 cgaactttat aatttcttag gattaacagt ggggttgaat atcaactcaa aatcttcgga
     6241 tgaaaaacgc gaggcttata attgtgatat cacttatagt acgaataatg aattaggatt
     6301 tgactacttg agagacaata tggtcgttta ccgccatcaa atggtacaac gtccgctgaa
     6361 ttatgccatt gtcgatgaag ttgactcaat cttgattgat gaagcgagaa cgccgctgat
     6421 catttcaggg caagcagaaa aatccacagc tttatataca agagcagaca acttcgtgaa
     6481 acgtttgaaa gaagaagaag attataaaat cgatgtacaa tcaaaaacaa tcagtttaac
     6541 cgaagcaggg atcgaaaaag cagaagaaac attcggtttg gataacttat acgacattga
     6601 aaatactgca ttgacccatc acttggatca agcattgaga gccaactata tcatgctttt
     6661 agatatcgat tatgttgtcc aagacggaaa agtactgatt gttgaccagt tcactggtcg
     6721 gatcatggat ggacgccgtt attcagatgg acttcaccaa gcaatcgaag ctaaagaagg
     6781 cgtagagatc gaagacgaaa cgaaaaccat ggcgacgatc actttccaga actatttccg
     6841 tatgtacaag aaacttgcgg gaatgactgg tacagctaaa acagaagaag aagaattcag
     6901 agaaatttat aacatccaag tataccagat tccgacaaat cgtccggtta tccgtgatga
     6961 tcgtccagat ttactttacc caacattaca aagcaagttc cacgctgtcg tgcaagatat
     7021 caaagatcgc taccgcaaag gtcaacctgt gttagtcgga actgttgcgg ttgaaacatc
     7081 tgagttatta tcagatatgc tgaatcaaga acgtattcct catgaagtgc tgaatgcgaa
     7141 aaatcacttt aaagaagcag agatcatcat gaatgctggt caaaaaggtg ctgtgacgat
     7201 tgctaccaac atggctggtc ggggaacaga tatcaagtta ggacttgggg taagagaact
     7261 tggtggtcta gcagttatcg ggacagaacg acatgaatct cgtcgtatcg ataaccagct
     7321 tcgaggacgt gcaggacgtc aaggagaccc tggtatgtca caattctact tgtcattgga
     7381 agatgatttg atgaaacgat tcggttcaga acgaatcaaa gctttcttag atcggatgaa
     7441 gatcggtgag gaagatgctg ttatccaaag caagatgctg acgaaacaag tagaatctgc
     7501 acaaaaacgt gtagaaggaa ataactatga cacacgtaaa aacgtcttac aatacgatga
     7561 tgtgatgcgt gaacaacgtg aagtaatcta taaacagcga caagaagtaa tcatggaaga
     7621 aaaaagctta tccaagccac taatgaacat ggtcaaacgg acaatcagtc gtgtagtaga
     7681 tgcgcataca caattagaga aagaaaattg gaatttggaa agtatcatcg attttgccgg
     7741 cagtactctt gtccatgaag atagtattac tcttgcagat atcgaaggaa aaacatctca
     7801 ggagatcaaa gagtatctaa acgaacgagc acaagaagta tttaatacca aagcggctca
     7861 actaaatggt ccagagcaac tgttggaatt tgaaaaagtc gtgatcttgc gtgttgtgga
     7921 ctctaaatgg acagaccata ttgatgcaat ggatcaatta cgtcagtcaa tcggcttacg
     7981 tgcttatgga cagaacaatc cattagtcga atatcaaaca gaaggctata agatgtttga
     8041 agatatggta ggcgccatcg agtatgaagt cactcgaatc tttatgaaag ctgagatccg
     8101 tcaaaacgta cagcgtgaac aggtttctca aggaacagct tctcactcag aagacggaga
     8161 tgccaaagaa aatagtaata ctagcgcgaa aaaacagcca atccatgtga acaaggtcgg
     8221 aagaaatgat ccttgtcctt gtggaagcgg gaaaaaatat aagaactgtc atggaaaaaa
     8281 tgcaaactaa tttctgacag caggattggt gagacaaatt ctttttttaa gaattcgtct
     8341 caccttcttt ctgttatttg ctgattctgt tagactagat ataatgaaaa aagtatagtg
     8401 aaagaaggaa aaaacatgga aatatccgaa attcgaaatc tcctgacaga aatgcaggaa
     8461 aaggtcacaa gtttcaggag gtctctttga cttagatcag ctggaagaag acatcgcgga
     8521 agcagaagca aaaatggctg aacctggttt ttgggatgac agcgaagccg cacaaaaagt
     8581 gatcagcgaa aataacgcta ataaagaaac ctatgaccaa ttccattctc ttgccgaaga
     8641 actagaagaa atcgaattga tggtggagat gctgcaagaa gaacctgatg cagcaatgca
     8701 agaagaagca gaaacacgta tcaatgcatt agatgaaaaa atgaagacgt atgaattatc
     8761 tatgctgtta gacggacctt atgatcgaaa caatgcgatc gtcgaattgc atccaggggc
     8821 tggcggaacg gagtcccaag actggggcag catgctttta cgtatgtata cacgttgggc
     8881 agagcagcat ggctatcaag tagaaacact agattatcaa gcaggtgatg aagcagggat
     8941 caagagtgtg accctgctga ttaaaggaca taacgctttt ggttatctaa aatcagaaaa
     9001 aggtgttcat cgccttgtac ggatttcgcc ttttgactca gcgaaacgac gtcatacttc
     9061 tttttgttcg gtagatgtga tgccagagct tgatgaaacg atcgatatag aaatcaatcc
     9121 agatgatttg aaaatcgata cgtaccgagc aagtggtgca ggtggtcagc acatcaataa
     9181 aacagaatct gctgtacgga tcactcactt gcctacagga acagtagtag ctagtcaggc
     9241 acaacgctca caattgaaaa accgtgagca agcgatgggg atgttaaaag ctaagcttta
     9301 tcaattagaa gtggaaaaga aagaacaaga agcagctgca cttcgaggag aacaaaaaga
     9361 aatcggctgg ggttcacaga tccgttctta tgttttccat ccctattcta tggtaaaaga
     9421 ccatcggaca aacgtagaga caggaaatgt ccaagcagtt atggacggtg accttgattt
     9481 atttattgac ggctatttaa aaatgcatct acaataagaa ctcattgtta aattgaaata
     9541 aaattgtaag attttgcaag catgttgaaa cattgccatg ctataatagc taaagactga
     9601 aaaagatatg gagagaacgc catgattgaa atgaaggatg taatgaagaa gtactcaaat
     9661 ggtacgaccg ctatccgcaa tctctcgatt gtcatcgaac aaggagagtt tgtctatgtg
     9721 gttggtccgt ctggagccgg taaatctaca ttcatcaaat tgatgtatcg agaagaaaaa
     9781 gcttcaaaag gaactttgaa cgtcgcaggt catgatctaa tagcaatcaa aaaccgcgaa
     9841 gttccttatc tacgcagaga aatcggcgtg gtgttccaag actataaatt attaccaaga
     9901 aaaacagtat atgaaaatgt tgcgtacgct atgcaagtta tcggcagaaa acctcgagat
     9961 atcaaaaaac gagtaatgga agtgctggac cttgttggtt tgaaacacaa agttcgagtc
    10021 tttcctagcg aattatccgg tggggaacag caacgtgtct ctattgctcg ggcaatcgtg
    10081 aatacgccta aagtacttat cgcggatgaa ccgacaggaa atctggatcc agaaaactca
    10141 tgggaaatca tgaaattatt agatcggatc aatgcccaag gaactactgt cgtgatggct
    10201 acacataaca gtacgatcgt aaatacgatt cggcaccgag taattgctat cgaaaacggc
    10261 cgcattattc gagatcaagc ggaaggggaa tatggatacg atgattagaa cctttttccg
    10321 ccatttatta gaaagtatca agagtttgaa acgtaacggc tggatgacag ttgcttcagt
    10381 cagtgcggta acgatcacgt tgactttagt cggtgtattc atggcagtta tcatgaatgc
    10441 aactaaatta gctcaggata tagaaggaaa cgttgatgta tctgtattcg tagatatcgg
    10501 tacaaaagac gaagagatga aaaagctaga aaaagaattg aatgacttag atcatgttaa
    10561 aaaagttgaa ttttcaagca aagaacagga attgaaaaaa atccaaaacg aaatgggtga
    10621 ttcctggaaa ttgtttgaag gtgacaataa cccgttatat gatgtgtatg tagtaagtgc
    10681 tactgatcct tcttatacaa aacaagtagc agaagaagca gcagatttga agaatgtttc
    10741 tcgttctgat tacggtggag cttcctcaga tcggattttc caaatcgctg gtgcagttcg
    10801 gacatgggga ttagttgcag cggcattgct gctgttcgta gcgatgtttc tcatttcgaa
    10861 cacgattcgg atcacgattt tgtctagaca gcgtgaaatt caaatcatgc gtttagtcgg
    10921 tgcaaaaaat ggatatattc gctggccgtt tttccttgaa ggtggctgga tcggtctgat
    10981 cggtgcgatt cttccgattt tgatcatcac atttggttat gcatggtttt tccaattgat
    11041 caatccatca ttattacgtt cccattattc attgattcgt ccacaaaata tcgtttggaa
    11101 aatcaatctt ttaatggtcg gcattggtgt gatcattggt tcacttggct cgatcatttc
    11161 tatgagacgt tttttgaaat tctaatacca caatataaat aaaatgagaa agttggacag
    11221 tttcgttcca gctttctttt tttattggct aggagaatag aaggaagcgg cttttttccc
    11281 tttactttaa aaaacaactt gggtattctt aagttggtag aagaagaggt gaagccgtga
    11341 aaattatcgt tgacaatttt tttacgatcc ttttgattat gaatattttg ctttccttta
    11401 tcatcgtttt tcgagaaaga aaggaaactg ctcaaacatg ggcatggctg ctcgttttga
    11461 tgttcattcc agttgtagga tttattttat atattttttt aggaagaggg atttccaaag
    11521 agaaaatctt tgatttgaag atccaaggga aaatcggtaa gaacctggaa attgaagaag
    11581 acaaacaggc attgatgcga gggctttatc ctcatccgcc tactggacaa gtagatgtga
    11641 aacaattgat ctatatgctc acggtatttg aaagtacgct ctatacgact aaaaatgaaa
    11701 tcactttatt tacagatggt cgtgaaaaat tcgatgcgct gattgaagat atcaagcagg
    11761 cagaagacca tatccacttc cagtattata tttatcgcag tgatgcatta ggtgaagaag
    11821 ttcgagatgc attgacagag gcggcaagac gaggggtaaa agtcagagtc cttcttgatg
    11881 catggggttc cacacaagtt tcttccagct tttttcagaa tttgaaaaaa gcaggcggag
    11941 aagtcgcatt tttctttcct ctatttgttc cgtatattaa tcctcggatc aattatcgca
    12001 atcatcgtaa aatcgtagtt attgatggga aaatcggata tacaggtggg ttcaatgttg
    12061 gaaatgaata tctaggattg gtaaagaaat ttggttattg gcgagacaat catttgcgta
    12121 tttacggaga agcggtgtat accttgcaaa accgtttttt gatggactgg aattctcagc
    12181 atacaaaaga agtaggctat tctcccaaat ttttcccgtc cattcacact actggtgata
    12241 tagctgttca aatcgtgaca agcggaccag ataccgaaca tgaacaaatc aaaatgactt
    12301 atttgaaaat gatttcgtta gccaaacggg agatattgat ccaaacgcct tattacatac
    12361 cggatggatc gattcatgaa gcactgaagt tggctcttct ttcaggcgta aaagttcata
    12421 tccaaatacc taacaaacca gatcatcttc tcgtttactg ggcaacgtat tctttcgctg
    12481 cagagctgat cgagtatgga gcaaggatcg aaacatatga gaatggattt attcatgcaa
    12541 agacgatgat tatcgatggt ggcattgttt cagttggctc agcaaatatc gatgttcgtt
    12601 catttcgctt ggactttgag gtcaatacac tggtttatga tgaacgaatg gcttcacgtg
    12661 taagaaaagc tttttttgaa gactcgaaaa tttctacgca tctcacaaaa gaaatgtatg
    12721 aaaaccgagg aataatcatc aagatgaaag aaggattagc aagattgatt tcgccgctcc
    12781 tttaaaacat aaaaaggaca tgagaaccat caacagatgg agatctcgtg tccttttcta
    12841 acggggccat ttctgagagt acgtcagaaa tggagaaagc gtctcgcatg agcgaaatta
    12901 actttggggt atctcttgtt ttttggggaa agcaagaaat aagctaatat atgctattaa
    12961 aagagacaca tttcaaagcc agtatagcat agaaactttt aatgagatag ttttttttac
    13021 aattatgaga atttattttg ttatttaatg attttgattc gttttcatca agtaatgaaa
    13081 atgataaaat aaacatactt taggattaaa ggagatttct aatgaaaaaa cttaaattat
    13141 tcttaccaat aataggatta gccattcttt tatcaggctg ttcaaagtgg attgatcgag
    13201 gagaatccat tacggctgtt ggctcttctg ctttacagcc tttagtagaa acagttgctg
    13261 aaacttacca gacagaaaat cctggaaaat tcatcaatgt acaagggggc ggaagcggaa
    13321 ctggtttgtc tcaagtacag tcaggagcag tcgacatcgg aaactctgat ttgtttgcgg
    13381 aagaaaaatc ggggatcgat gcctcagcat tagtcgatca tcgagtagca gttgttggga
    13441 tcactcctat tgtgaacaag gatattggcg taaaagacat cagtatcgaa aacctgaaaa
    13501 aactatttac aggcgagatc aaaaactgga gtgaagtcgg tggaaaagat cagccagtag
    13561 ttatattgaa ccgcgcttca ggaagcggaa cccgtagcac gtttgaaaaa tgggtattgg
    13621 acggagaaac agctgttcag gcacaagaac aagattcaag cggaatggtg cgccagatcg
    13681 ttgccgacac acccggtgca atcagctatg ttgctttttc ttatgtttcc gatgatgtag
    13741 atacgttgaa tgttaacggt gtagaaccga cagatgaaaa tgtgacaacg aacaaatgga
    13801 cgatttgggc atatgagcat atgtacacaa gagatcatcc aaaaaaactg acaaaagaat
    13861 ttttagacta tatcttatct gatgaagtac aagataacat cgttggagaa ctaggttata
    13921 tccctgtttc tcatatgaaa gtcgaacgtg attggcaagg aaatatcgtt aaagagtaat
    13981 ctttacacaa aatttacaaa cttagctaaa cttttacatg ttattaaaac caaattgatg
    14041 ttcaatttgt acactgagtg agtatgttaa acctgattaa gggggagtca tctgtggaag
    14101 atgtgaaaaa agtattatta acaaaatcaa aacgttcaaa aatggaacag cgtggaaaat
    14161 tcatcagttt tttatgtatc gcgctgatcg tgttggttgt attatctatt ttttattttg
    14221 tagctagtaa aggattggcc acctttttta ctgataagat caatgtattt gattttctgt
    14281 ttggtacaga ttggaatcca agccaaatcg gagcaaatgg gaaaccaatg gtaggggcat
    14341 tgcctatgat cacaggttcg tttattgtga cctttttatc tgctatcgtt gccacgccat
    14401 ttgccattgg tgcagcagta ttcatgacgg agatctctcc taaaaacgga acgaagatct
    14461 tacagccggt catcgagctg cttgtaggta ttccttctgt cgtttatggt tttatcggtt
    14521 tatcagttat cgtgcctttt gtcagaagta tttttggcgg gacagggttt ggtatcttag
    14581 ctggtacatt tgtgttgttc gttatgatct tgccgactgt cacaacgatg actgttgatg
    14641 cattaaaggc agtaccacgg cactatcggg aagcttcatt agcgcttggt gccacaagat
    14701 ggcaaacaat ctacaaagtc gtgctacgag cagccgtgcc cgggatttta acagcagtcg
    14761 tttttggtat ggctcgtgcg tttggtgaag ccttagctat ccaaatggtc atcggtaatg
    14821 cagcattgat gccaacagga cttactactc ctgcttctac attgacgtcc atcttaacaa
    14881 tgggaatcgg aaatacaatc atgggaacag ttgaaaataa tgtgttatgg tcattagcgc
    14941 tgatcttgct attgatgtca ttattcttta atatcgtgat ccgtatgatt gggaagaaag
    15001 gagagctgaa ataatgaacg caaaacgctc agataaaatt gctacaggtg ttttatatat
    15061 agtttcgggg atcatcgtat tgattttagc agctttacta ctttatatct tagttcgggg
    15121 aataccgcac atttcatggt ccttcttgac cgaaccttcc aaagcctacc aagaaggtgg
    15181 tggaatcggg atccagctat ttaactcgat ttatttgctt ttgatcacga tgatcatcag
    15241 ttttcctatt tctttaggtg cgggtatcta tctttcagaa tatgctggaa aaaactggct
    15301 aacagatgtg attcgcacgt cgattgaaat cttgagctcg ttgccttctg tcgttgtcgg
    15361 tttattcggt ttcttggttt tcgttattca attccagtat ggtttctcga ttatttctgg
    15421 tgcattggct ttgactgtat tcaacttgcc tcttttgact agaacagttg aggagtcttt
    15481 acaagcggtc cattacacac aacgagaagc aggattggcc ttaggtttgt cacgctggga
    15541 aacagtgatg aaagtggtgg ttccagaagc gacaccaggg attttgactg gtgtgatcct
    15601 aagttctgga agaatttttg gtgaagcagc tgcattgatc tatacggctg gacaaagtgc
    15661 acctgcgtta gattttacga actggaatcc attaagtgtt tcaagcccga tcagcatttt
    15721 ccgtcaagct gaaacattag ctgtccatat ttggaagatc aatacagaag gcacgatgcc
    15781 tgatggtgtt tctgtttcgg ctggcgcttc tgccgtgttg atcattgctg ttttactgtt
    15841 caacttcggc gctcgtgcga ttggcaaacg attataccga aaaatgactt cagcctaagg
    15901 agaagaagca aaatgaaaaa atataactgg aatgaaacaa atgtcatcac catgccaaaa
    15961 gagaaagaag tagcactata tacggatgat atacatgtct ggtatggcga caatgaagca
    16021 atcaaaggag tggatctgga atttgaaaaa aataagatca ctgcactgat tggtccttcc
    16081 ggctgcggaa aatctacgta tcttcgttcg ttgaatcgaa tgaatgatgg gatcgctaat
    16141 acgaaaatca ctgggaaaat catgtatcaa ggcgtagata ttaatgcgcc tcaagtggat
    16201 gtttatgaga tgcgcaaacg gattggcatg gtttttcaac gtcctaatcc gttcagcaag
    16261 tcgatttatg acaatattac atttgctttg aaacagcacg gcgaaaaaaa caaaaagaaa
    16321 ttagatgaaa tcgttgaaac aagcttgaaa caagctgcct tgtgggacca agtaaaagac
    16381 agcttggaca aaagtgcctt ggctttatct ggcgggcaac agcaacgttt atgcattgct
    16441 cgtgcgatcg cgatgaaacc tgatatcttg ctgctagacg agccggcaag tgctttggac
    16501 cctatttcga caggaacggt tgaagaaaca cttgtaaact tgaaagaaga ctatacgatc
    16561 atcatcgtga cgcataacat gcaacaagca gctcgtatca gcgactatac tgcctttttc
    16621 tatctaggaa aagtaatgga atatgacaaa actaacaaga tatttaccag accaaaaatt
    16681 caggcaaccg aagattatgt gtccggtcat tttggttaag acggaggcct caacatgaca
    16741 aaagaaatta tttcatctaa agatcttcat ctgtattatg gaaagaaaga agcactaaaa
    16801 gggatcgatc taagtttcaa tcaaggggaa atcactgcga tgatcggtcc ttctggttgc
    16861 ggaaaatcca cttatctgcg ttctttgaac cggatgaatg acctgattcc gaatgtaacg
    16921 atcaccggaa gtgttttata taaagacaaa gacatctatg gtccaaaaac agatgttgtt
    16981 gaactaagaa aagaaatcgg catggtattc cagcagccaa acccatttcc tttttctatc
    17041 tatgaaaatg tcatctatgg attgaaatta aaaggggaaa aagataaaaa agtccttgat
    17101 caagtagttg aagaaagcct gaaggcagcg tctgtttggg atgatgtgaa agacaaattg
    17161 cataaaagtg ctttatcttt atccggcggg cagcagcagc gtgtatgtat cgcacgtgtt
    17221 ttggcagtta atccggaaat catcttattg gatgaaccaa caagtgcgct tgatcctgtt
    17281 tctactggga aaatcgaaag tatgctgtta gaattaagag agcggtatac gatgatcatc
    17341 gtgacccata atatgtctca agcttcacgt atttcagata agacggcatt ctttttagat
    17401 ggtcacttga tcgaatacaa cgatacgaag aagatattca tgaatccaga aaaacaagag
    17461 acagaagatt atatttcagg tcgatttgga taaggaggaa acggaatgct acgtacacaa
    17521 tttgaagaag aattgctgaa tctccataat cagttctacg aaatggggat gatggtgagc
    17581 agcgccgtgc acaagtcagt tcgtgcatac atcaaacacg ataaaatctt agcccaagaa
    17641 gttatcgaaa acgatataaa tatcaataac atggaaacac gcttggagaa gaaaagtttt
    17701 gaaatgatcg cattgcaaca gccagttaca actgatttgc gtatgatcat tacggtcatg
    17761 aaagctagct cggatttaga acgtatggcc gatcatgcgg tgtctgttgc taaatccacg
    17821 attcgcgtaa aagggcagac gagaataccg gaaatcgaaa aagagatctc cgatatgtcc
    17881 gattatgtga aaaaaatggt ggacaacgtc ctagttgctt atgtcaaaac agacgaaaaa
    17941 gacgcacgta cgatcgccaa tatggatcaa agagtcaatg actatttcaa tcgaatctat
    18001 aatgcaacaa tcaaaaatat gcaggaaaat cctgagacag tcatcagtgg aacagactac
    18061 ttgaatgttg ccagttatct agaacggatc ggagactatg tgacaaacat ctgtgaatgg
    18121 atcgtctact tggctacagg gaaaatcact gagttaaata cgaaccacaa tgagattttc
    18181 taaactgaag ctgtgattat gccgtttgtt tatgaaaaga ggttgtgaaa aagctgttct
    18241 acatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg
    18301 acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa
    18361 aacatgtcac aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt
    18421 agcatcatca ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagcc
    18481 gctttatatg aagtacctgt catcgagata gaaaaagtac gaataaaaga ggatcatcaa
    18541 ttgattacag gaaaactgat gaactcggat caaaaaggag aatcgattta tttatcggtt
    18601 ccttatcaaa aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc
    18661 caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa atgatggctg gcttttcttc
    18721 ttcacaagta tcttcattgg cgccatgttg cttattggcg gaaaacaggg tctatttgct
    18781 ttaggaagtc tcatcatcaa tatcgtttta cttttacttt tgttgctcat ctttactaaa
    18841 acagaaggga tttctctatt aaataaatct atcctgttcg tcgttatagg gatgattatt
    18901 agcatattgg ctttagatgg atggaataga agcagtataa tcaaaatttc agctgcagtt
    18961 acgagtgttt ttttagcatt ttttatttgt cttttgacaa tgaatcattg gaaagaccaa
    19021 ggactgcgct atgaggaact gaattatctg acacgaccgt atcgttctgt ttttctttct
    19081 agcgtactga ttggaacagc tggaggaaca ctcgataccg ttatcacagt cattgcgaca
    19141 ttagaagaat tgactaagcg acaaccagaa ataacagcga aacagttatg gctttcagga
    19201 aggcaagtgg gtcgagatgt gattggctcg atgaccaata tccttttgtt cgtctatatc
    19261 agtgggtcag ttccatcgct tcttttatat ttaggaaatc aatggtcttt caaagaaacg
    19321 atagaacagc atttatcatt ggaattttta cgcgtcattg ctggcagctt aggaatagta
    19381 ttatcgatcc ccatctcggt cctctttttt ctgactgtaa ggaggctgaa acgatgaatg
    19441 tacttattat acttgttggg attttagcaa tcagcgtgct acttattggc ggtacgcaag
    19501 gtatgtatat tcttttaggc ttattcatca atttagggat ctttttcctg ttgttattcg
    19561 gttatcatca gaagtggccg atactggcat tgtcggtcat aggattttta ttgattgctg
    19621 tggttatctt attttttatc aacggttata atctaaaaat gcgtgcagct tttgtgagta
    19681 tactgatctt tttattttgt ttcctactat tgcttcctat cactgatttt ttagcgatcc
    19741 aaggttttac atcggtagaa ctagaagaat tatctggctt agataagact ttagcgattg
    19801 attttagatt acttacgaga tcgttgcttc tgattagtct tagtggtgct gttttagatg
    19861 cgagtgtagc aatttctagt gggacattcg aagtatatca ggcaaatccg caattatctt
    19921 tttaccaatt gcgccattct agtttcgcta ttgctaaaaa aatattggcg tcaacagtaa
    19981 tgacacttct ttttgcattc atgggaagtt ctttagcgtt gatcctctgg tttattgatt
    20041 tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt tgttctagaa tatacgatgg
    20101 ctattcttac cacattgtcc gcactaattg ttcttccttt aacctgcgtg actacagcat
    20161 atctctttac aaaaaagaaa gaacaactca agatggagta aaagttacaa cttaagtcct
    20221 atgacatttt tactgaatca gtgcataata tggatgtaag gaaaagcttg caaacaattt
    20281 tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat tttagattta gtgaaaaaag
    20341 gaatcctttc gactgaagaa ggcttagatt tattagaaag catggcaact gaaaaagacg
    20401 aaaagcaaat caaaaaagaa gcagacaagg taactgctag tcataaagaa aaagataagg
    20461 caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga aatttctgag ccagttgatc
    20521 caaaggaaag agaaagacaa gatcaagaaa acttagaaaa gatcttagat gaactagcaa
    20581 ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa tgctcaattc gctgacaata
    20641 aggcagcacg caatgagaaa caggaagcat tgatgcagct gaatacaaaa gaagaattag
    20701 gcgagttgac agaagaagaa ttagcacagc gtcaggcgtt agaggcagaa atcaaagagt
    20761 tagaagctag tggcgataca ctgttagaag aacaattgaa attagaagca gaattaaaag
    20821 atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt tactgataag tttgaattgc
    20881 cagatgattg gaaagatcaa gcaacagata cactgaatca agtaggcgaa aaaatgtcag
    20941 aagctggatc acagttaggc aaattcttga agaaaacatt ccaaactgtt tcagaaacag
    21001 tgaatgacaa catggaatgg aaagatgtca gcttacgtgt ccctgggatt gcgacaacga
    21061 aatttgagca tgaattttac tatgaagctc ctgcagcaag tatccttgat atcaaggcag
    21121 caaacggaaa cgtgacgtta aaaacgtggg acagcaacga tgtgaaagtt gaagctaaga
    21181 tcaaacttta cggaaaaatg ggtgctgaac catttgaagc attctctgaa cggagccaga
    21241 ttgaggttaa tgaagatcat atctccttcc aaattccaaa taaacgtgtg cgtgcagacc
    21301 ttgttttcta cttacctaaa cgagtatacg accacgcagc tattaaactt ctaaatggca
    21361 acatcatgat tgaaacattg gaagctaaag atatttatac aaaatctacg aatggtaaca
    21421 tcatcgtgga ccaattaact gcaacgatgc tggaagtaga aggtgtaaac ggcaatatcg
    21481 atattcgaaa cgggaacatc ttagattcta ttatcgaaac agtaaatggt acagtgacat
    21541 ttggtgcgac agcagaaaat ctttctgtgt ctttagtaaa tggtgatgta cgtcttacga
    21601 ttaaagaaga taatttgaaa aaagtagaag caagttcagt gaacggaaat gtcaaagtcg
    21661 ctttaccaga tggcatcggt ttggaaggac atgctaaaac aagtcttgga agtatcaata
    21721 gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga acggacaaac caaatgttgc
    21781 aattccgtcg tgtttcagat gatgagatcg cgcaagtgca actttcaacg acaacaggaa
    21841 gtatctattt aaaagataca gataaataaa gaggttgtga aagagatgtt cagccttgag
    21901 caataagaag cgattttgta aaatagcttc ccctatttta caaaattgtg ccttattgcc
    21961 gataggctat ctcttgaaca ccgattaaga agaaggttgt cacaacgatt ttcttcattt
    22021 aaaatagtag aacagaggtg agacatgatg aaaaaaaagt tgacaaaatc caataaaaat
    22081 gttgttttga caggtacttt agcagggatt ggggaatata tcgggattga tcccactgtt
    22141 atccgtgtgc tttatgtatt cctaagctta gttgcttttg gaagtccaat cattttatac
    22201 attttattag ctttgattat cccatctgcg cgttctgcac gaacaaacta tggacataac
    22261 aatgcatatt atgaaaaaaa caattatcgt gaacaaacaa aaaaacgcaa agaagcggaa
    22321 aaaatcgatg atgacgaatg gagtgacttt taatgtcgta ctttcagcgt attttggtta
    22381 atacgttaac attcatatcg ttggctgttc tttttcctgc gatggtccat gtgagcagta
    22441 tttggacagc cgtccttgcc agcttcgtat tatctgtgtt gaacatgttt gtcaaaccga
    22501 ttctgacgat cctgtccctg ccctttacat tagtcacatt gggattgttt acgtttgtta
    22561 tcaatgcagc gattcttaaa atgacttcct tttttgtagg agcagaacat tttagttttt
    22621 cttcatttgg tgcagcgtta ttcgtagcta tcttgatgtc acttgtcaat gtaatcgtta
    22681 gtgaacataa cagcagaaag taaaaaaagc tgtgccgaga tctcggcgca gcttttttgt
    22741 ttatcgcgaa ttgtaaaatt aagttagaaa aataaaaagg catttatggt acactcaaat
    22801 tgtatttccg acgaaagaaa acaaaggagt gtaaccataa atgacctaca aacatcttac
    22861 catagacgaa ctgacaatga tagaatcata ttatcttcaa cataataagc cggttgaaat
    22921 cgctaaccga atgggacgtg ctatacaaac tatttataat gtagtcaata agttcaagca
    22981 aggtaagact gctcttgatt attggcacca gtataaagaa aataagaaaa aatgtgggag
    23041 aaaagtcatt caattacctg ctcatga
//
LOCUS       DAJSMK010000038        23036 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.039, whole genome shotgun sequence.
ACCESSION   DAJSMK010000038 DAJSMK010000000
VERSION     DAJSMK010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.039"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            31..771
                     /locus_tag="ON488_001468"
     CDS             31..771
                     /locus_tag="ON488_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCR3231669.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGETNYIESSKN"
     gene            complement(863..2050)
                     /locus_tag="ON488_001469"
     CDS             complement(863..2050)
                     /locus_tag="ON488_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCR3231670.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
     gene            2372..3214
                     /locus_tag="ON488_001470"
     CDS             2372..3214
                     /locus_tag="ON488_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCR3231671.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            3214..4161
                     /locus_tag="ON488_001471"
     CDS             3214..4161
                     /locus_tag="ON488_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCR3231672.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            4176..4409
                     /locus_tag="ON488_001472"
     CDS             4176..4409
                     /locus_tag="ON488_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HCR3231673.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            4740..5324
                     /locus_tag="ON488_001473"
     CDS             4740..5324
                     /locus_tag="ON488_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3231674.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            5455..6123
                     /locus_tag="ON488_001474"
     CDS             5455..6123
                     /locus_tag="ON488_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HCR3231675.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            6134..7549
                     /locus_tag="ON488_001475"
     CDS             6134..7549
                     /locus_tag="ON488_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HCR3231676.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            7567..8136
                     /locus_tag="ON488_001476"
     CDS             7567..8136
                     /locus_tag="ON488_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HCR3231677.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            8246..10000
                     /locus_tag="ON488_001477"
     CDS             8246..10000
                     /locus_tag="ON488_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231678.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            9960..11726
                     /locus_tag="ON488_001478"
     CDS             9960..11726
                     /locus_tag="ON488_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231679.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVTMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            12249..12518
                     /gene="rpsN"
                     /locus_tag="ON488_001479"
     CDS             12249..12518
                     /gene="rpsN"
                     /locus_tag="ON488_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HCR3231680.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            12533..12712
                     /gene="rpmF"
                     /locus_tag="ON488_001480"
     CDS             12533..12712
                     /gene="rpmF"
                     /locus_tag="ON488_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCR3231681.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            12744..13121
                     /locus_tag="ON488_001481"
     CDS             12744..13121
                     /locus_tag="ON488_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231682.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            13142..13291
                     /gene="rpmG"
                     /locus_tag="ON488_001482"
     CDS             13142..13291
                     /gene="rpmG"
                     /locus_tag="ON488_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCR3231683.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            13315..14298
                     /locus_tag="ON488_001483"
     CDS             13315..14298
                     /locus_tag="ON488_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCR3231684.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            14328..14450
                     /locus_tag="ON488_001484"
     CDS             14328..14450
                     /locus_tag="ON488_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HCR3231685.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            14468..15991
                     /locus_tag="ON488_001485"
     CDS             14468..15991
                     /locus_tag="ON488_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HCR3231686.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIIGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSKHEIAQEMMAH"
     gene            16015..16254
                     /locus_tag="ON488_001486"
     CDS             16015..16254
                     /locus_tag="ON488_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231687.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(16447..16908)
                     /locus_tag="ON488_001487"
     CDS             complement(16447..16908)
                     /locus_tag="ON488_001487"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCR3231688.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(17103..17321)
                     /locus_tag="ON488_001488"
     CDS             complement(17103..17321)
                     /locus_tag="ON488_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231689.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            17439..19055
                     /locus_tag="ON488_001489"
     CDS             17439..19055
                     /locus_tag="ON488_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCR3231690.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(19296..20636)
                     /locus_tag="ON488_001490"
                     /pseudo
     CDS             complement(19296..20636)
                     /locus_tag="ON488_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(20912..21067)
                     /locus_tag="ON488_001491"
     CDS             complement(20912..21067)
                     /locus_tag="ON488_001491"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HCR3231691.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(21259..21453)
                     /locus_tag="ON488_001492"
     CDS             complement(21259..21453)
                     /locus_tag="ON488_001492"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCR3231692.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKC"
     gene            complement(21363..21695)
                     /locus_tag="ON488_001493"
     CDS             complement(21363..21695)
                     /locus_tag="ON488_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3231693.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRLAISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(22209..22400)
                     /locus_tag="ON488_001494"
     CDS             complement(22209..22400)
                     /locus_tag="ON488_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231694.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(22494..22880)
                     /locus_tag="ON488_001495"
     CDS             complement(22494..22880)
                     /locus_tag="ON488_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCR3231695.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
BASE COUNT         7814 a         3411 c         4351 g         7460 t
ORIGIN      
        1 ataatcatta tcatttagaa ggagaaagtt atgttagaag tgaaaaagct taatgtttgt
       61 tataacgatt ttttagcatt gaacgagatt tctttaaaaa tacaagaagg tgctttaaca
      121 ggtattattg gtccaaatgg tgctggaaaa tctacattgc ttaaagcaat gttaaatatt
      181 atccctcatc agggagaggt ctccattaat aatgaagata tcaataaaaa actggtgaag
      241 attgcatatg tagagcaaaa agctgatatt gattttactt ttccaataaa agtaaaagaa
      301 tgtgtatcta tgggaacata tgccggaatg aaagtttttc aaagaattaa aaatgcagaa
      361 tggcaaagag tttcaaaggc tttggaaaag gtcgatatgg gaaaatattc taatcatcaa
      421 ataggagaat tatctggagg acaatttcaa cgtgtacttt tagcaagatg tcttgctcaa
      481 aatgcggatt tcatattttt agatgaacca tttgtaggga tagacttagt tagtgaacga
      541 ataattatgg atacgttaaa agaattgaaa catcagggaa aaacagtgct aattgtgcat
      601 catgatttaa gcaaggtaaa gaagtatttt gataatatta ttcttttgaa tcgaaatcta
      661 attgctcacg gaagtgtaga atctgtattt aatgaagaga atttaaaaaa agcctatgga
      721 gatactatat ttattggaga gactaactat atagagtcaa gtaaaaatta gccaaatcaa
      781 aaaatatttt ataacagata attccgaaaa aagggtacaa caaataagct tcttaccatt
      841 agtttttttg aatgttcaat agctaatcag aaacaattat ataaggctcg tttttagtca
      901 aaatagcatg aatcacgtaa caaagcttac gagaaaccgc acctaaggca gttagatgat
      961 gttttccttc ggaaactttt ttctggtaaa acgcactaaa aacaggatca cattgagaag
     1021 ctactaaagc cgccgaaaac aaggcttttc gcaaatatgg agaccctcgt ttactcataa
     1081 cattatgcgt tgcctcatat tgccctgatt gtgtcacgga agcgtctatc ccagcgtaag
     1141 caacgagttt tttcgggtta gaaaattttt gaatatctcc gatctcacca agaatagtcg
     1201 caccgtttat aggaccaatt ccaggaattg tgagaataac agaatttaaa gtgtccatta
     1261 tgtgcttgat ttctctttcc gtttccttta tttggctttc aatgaatttt aattgttcaa
     1321 tcattgaacg tagttggaag gtgaacgctt cttgagcaaa ttttactcca aaggagttag
     1381 aagctgcttg cttcaattgg tccgcttttt ctgccttgat tcggttcctg cttaactcag
     1441 ctaagtattg ggccaaagtt tctgaggaaa tgttttctaa gtcgatcggg gcactaaacg
     1501 ccagcaataa ctctttagaa gcttttccga aaacgccctg tttggtaaaa atcgtcgcgt
     1561 attctggaaa gacttgatcc aatacggcta taatttttct tttgaagtcg ctcgctgtac
     1621 ctactaaata agttcggtaa cgagaaagtt gtttcaaaga aaaaacattt tcatcggata
     1681 agaccgtttc gacaaatgag ccatagcgca ttaagtcagc aatcaaaaca gaatcaataa
     1741 tatcgttttt tcgtttccgt atttctgtac ctttacgcca tccgtctgtt tgaaggggat
     1801 tcacaacgtg aatcaaataa tctgattcgt gaaggtatga aaagatggac agccaatagt
     1861 gccccgtggc ttccatccct ataacaaagt cactgggtgc tccggaatag tcgaccattc
     1921 gctcaattaa tgactctgct ccttcagtgg tgttaggaaa tgaaaaacct tttagtaata
     1981 cctttccttc ctcgttcatg atagaagcaa cgtgagtgcg tttaccgata tcaatgccta
     2041 aaaagtacat gtatatctga cctttcaaaa aaagaatttt ggattgaaat ccactcaact
     2101 gaaaagcgtc actaccttgt acgagatacg gagtaaagta aggactttca acatctaact
     2161 catacgcaat acacttatca gagagaggag ccagtctctc gagtgcgggt tcaatgaccc
     2221 aaggggggaa cggcttagcc tctcaatcca ataaatatat tatctcaaaa gaaatgagtt
     2281 aataccaaat taaaataacg atggttcata gggttatcca atcaaaaccg gaaggttaaa
     2341 accctaactc taatatacaa gggggaataa tatgcttcaa aattttatta atggtctgta
     2401 tgactttcac tttttacaga atgctctaat tacatctgta gttataggga ttgtttctgg
     2461 aacagtaggt tgttttatta ttttaagagg aatgtctctt atgggtgatg ctatttctca
     2521 tgctgttttg ccaggagtag caatttctta tattttaggt attaattttt ttattggtgc
     2581 gattgtattt ggtctattag cttctatcat tattactttt ataaaaagca atagtgtaat
     2641 aaaaggagat acagcaattg gtattacttt cagttctttt ttagcattag gagttatcct
     2701 tataggagtt gcaaatagct caacggattt atttcatatc ttatttggaa atattttagc
     2761 tgtacaagat attgataagt ggattacaat tggcgtttct gttttagtgt tggttacagt
     2821 tgttctattt tttaaagaat tattaatcac ttcttttgat ccattaatgg caaaagcaat
     2881 ggggatgaat gtcagttttt atcattatct attaatgatt ctattaactt tagtagcagt
     2941 aacagctatg caaagtgtgg gaactatatt aattgttgca atgttaatta caccagctgc
     3001 tacagcatat ttatatgcaa acagcttaaa aactatgata tttatttcgg cgacagtcgg
     3061 agcgtgctca tcattgctag gtttgttcat tggttatagt tttaacatag cagcaggatc
     3121 aagtattgtt ttaacagcgg cattcttatt tgtaattagt tttctaatct caccaaaaca
     3181 aaaattttta agaaagaagg agagaaagtt atgatgagaa aatggaaagc agtactggga
     3241 agtctgggga ttttgattgc tctttttata ttcggggcat gttcaacaaa tagtaaagac
     3301 aaagatacag tggcttcgaa cgaaaaatta aaggtagtag ttactaattc gattttagca
     3361 gatattactg aaaatatagc aaaagataaa attgatttac acagtatcgt acctattggg
     3421 aaagatcccc acgaatatga acctttgcct gaagatgttc aaaaaacttc aaaagcagat
     3481 ttgatttttt ataacggtgt taacttggaa actggaggaa atgcttggtt tacaaaatta
     3541 gtaaaaaatg cgaacaaaga ggaaaacaaa gactattttg cagcaagtga tggcatagat
     3601 gttatttact tagagggtca gagtgagaaa gggaaggaag atccccatgc ttggttaaat
     3661 ttagaaaacg gtattattta cgctaaaaat attgaaaaac agttagcgga aaaagatcct
     3721 gataataaaa aattctataa agaaaatcta gataagtata ttgaaaaatt ggattctcta
     3781 gacaaagaag ctaaatctaa atttgcttca attccgaatg ataaaaaaat gattgttaca
     3841 agtgaaggat gctttaaata tttctcgaaa gcgtataatg tgccttctgc ttacatttgg
     3901 gaaatcaaca ctgaagaaga aggaacacca gatcaaataa aacacttagt tgaaaaatta
     3961 cgcacaacaa aagttccctc cttattcgta gaaagcagtg tggacgatag accaatgaaa
     4021 acagtatcaa aagataccaa tattcctatc tattcaacga tttttactga ttcaattgca
     4081 gaaaaaggac aagatggtga tagttactat gcgatgatga aatggaacct ggataaaatt
     4141 gctgaaggcc tttcgaaata atttggaggg taggtatggt acaaattaaa acgactacta
     4201 tactaattta tttactagca attcaggaat tatcaaaaag aaaaaagaaa ttaaaaaata
     4261 atgatttagc aaaagttcta agtgttagtc cagcatctgt aagtgagatg ctggctaaac
     4321 ttagatatga ggactattta gatataggat ttcaattaac tgataaaggg aaaaaattta
     4381 ttgacgatta caaaaaaggt tttaagtaaa agactttatt tttagggagg ataagaaaat
     4441 ggctattgga gtgattatga taggacttac cctaatagct ggatataatt tttttaaatc
     4501 tttctcggat tattttagaa aaggtgaatg atttagatga gtctattaat tcttgtagga
     4561 ttgctttttg tatcagttat tttgctcttt ctcattagtt tagctctaag aaatgagttc
     4621 agtaatagac gttaacgatt gaaacttcaa gtcctgtgta agataatata gttaattcat
     4681 cttattagga ggaagtaccc atagaaacca gagattatat tacaactcac caaaaattaa
     4741 tagaaagtgg actaagccat tttgaaaaag aaggatttca gcaaactaag ataaggcaac
     4801 tgtgcttgac cgcaggcgta actacgggtg ctttttataa acattttact tctaaggaag
     4861 cgttatttga agaaattatt cagccgcata ttaatgcgct tattaatatg tataatgaag
     4921 agtttaccaa atacctctta aacttagaaa atatagatat agagaaaagt tggagagaga
     4981 acttcaatga attagatcca tttattaatt atatttttga gaataaacgt atattcgatt
     5041 tggttttatt ccaatcagct ggaaccaaat atcaagatat tgttgaaaaa attacatcat
     5101 ttgtgacaaa aaagacagtc tgttgtctag ataagttaaa gactatcgga atgatcaatc
     5161 aaaatttagt ctttaatgaa gaagaaatcc acttctacat ttactcattc tacgctacat
     5221 tctatgatat attgaagcat agctattcaa aagaaaagac tatgctatta accagaagat
     5281 tgtatcaatt ttctgttcct gggtggattg aattactgag ttaattaaaa aaaagcttgc
     5341 attgagaatt gttctcagtt atgctttttg ataagatcgc actgttatct gaataacggt
     5401 gcatttttgt cagcttaaga taacagtgcg atcttatttt ttggaggtga aagagtgtca
     5461 aaaatcaatc cgttaacctt gattacttta aatatttttt ttccggtcat tattttttta
     5521 ggaaagggaa atatatttca agtggggtgt ttcattattg ctacagtttt agtattgatg
     5581 tttcgtaaaa taaagacatg tatttatttc atcttgattt attcagttct gtttttagta
     5641 atgaaaatta ttgatgctat caagatagag ttttttacta tattttttgg gacatcctta
     5701 tatattgtat ttcgaatgtt gccggtcgta atgatctcat ggttgttggt tagtgtctat
     5761 actagcaatg aattattatc ctctttagaa aaaatacatt taccgaaaaa aataatgtta
     5821 agtattacag tagtgatcag attctttccg acttatcgtt ctgaaataag aatgattaaa
     5881 gaatctttaa aaatgagaaa cattcgcttg tctttttttc agcctctgca atatttggaa
     5941 tttctgttag ttcccgttct tatacgtgca actatgattg ctgaagaaat gaccgctaat
     6001 gcaataacaa aggggataga atctcctgtg aaaagaagtt cttactataa aacaaacatg
     6061 agcttattag actatatcat cctgttttcc gttactattt ttttcttaag tattttgatt
     6121 tgaggtgaaa gaattgtttg aatttaacaa tgtttctttt tcatataagg atgttaagga
     6181 acaagcgctt gttgacctta atttttcaat aaaaaaaggc agtcttacat tgattactgg
     6241 ttcttctggg agtgggaaat ccacactatt aaagttaatg aatggactta ttccaagact
     6301 ttatgacgga aaattggttg gggaaatttt atttgaaaat aactcgctac aatccttaac
     6361 acaagaaagt atatcaaaaa atattggcta cgtaagtcaa gatcctagag gacaattctt
     6421 tacaacaaat acaacgagtg agttagtatt ttcgatggaa aactttggat ttacaaaaga
     6481 gcatatggat aaaagaatca atgaattagc tgaattatta gatctttcaa atatattaga
     6541 taaaaacatt ttttcgctat caagtggtga acggcagaaa atttctattg gatgtagttt
     6601 atcgctaaac tctaaattaa ttatattgga tgaaccgtct tcaaatttgg acttcaaagc
     6661 gactaagaaa cttgctgact tactttgtga tttaaaaaat aaaggattta ctattgttat
     6721 agctgaacat cgtttttact atttgaaaga attaattgat caagttctat ttgttaaaaa
     6781 tagaactgta aaaactacaa ctattcagtt gttaaaaact gaaaacaata acgcattaag
     6841 gaaatttgac atttttaata gttcgattga agttccctat atcgaaaagg taagtgcaga
     6901 tgtattaaaa gttgaagaaa ttacttatga aaatattcta aaagacataa attttgatgt
     6961 caaagttgga gatgttattg gtttggtagg gaaaaacggt gtggggaaaa caaccttact
     7021 aagaatactc atgaagatta ttcgccctac caaaggaaag ataatcgaaa ataaaaaaaa
     7081 tttgtcatcg ccgtttttag taatgcaaga aatggattac caatttttca cagaatcagt
     7141 gaggagcgag ttagccctgg ggaatgaaat agttagtaaa gatcagcaag aaaaaatttt
     7201 aaaaaaaatg gaactttata aaatgaaaga tcaattaccg tttgatttat ccggtggaga
     7261 aaaacaaaga ttattggttt ctatagcttc attgtcaaaa actaatttat ttctatttga
     7321 tgaacctaca agtgggttgg attatatcaa tatggaaagg attgctgacc ttattaaaga
     7381 cttaaaagaa aagggtgcag tagttatagc cactcatgat ccggaatttc tttataaaac
     7441 atgcaataga attatttatt taaaaaatgg tggaataaaa aaagatataa aacttagagt
     7501 agaagattca actttgatag aacagatttt taatgacata acgaaataga attgaggaga
     7561 atatatatga aaacaaaaga ttatattttt attggtttag ctacagttat ttccctagta
     7621 atttactttt tttcaataat ggttagtagt attggtgggg cgtttggtca cagcatatcc
     7681 ccagggattt ttggattatt atctggaatc atatttgttt atattagcta taactaccct
     7741 agaaaaggaa tttttactat ttacacaatt gttttattgt tattttttac gttaatgggc
     7801 ggggcgtact taccttggtt tatcagttcg attagtatgg cgatcttagc tgatattatt
     7861 ctatctgtat ttggatatga tcgagcaatt cctcaagttg tgtcttgggt tctaatgcaa
     7921 ctaggcagtg ctgccggaca gtggattccc atatggttct ttacagatcg ttttcgtcaa
     7981 gactggatag atagaggaca atctgctgca acaatggatg caatgatcca ctacgcggtg
     8041 ggtatatggg gaattatttc agtgttagtt gtagcaagtt tatctatgat tggtgtattg
     8101 attggaagaa aagtcttaaa aaaatacaaa aaatagaacg tagtttacct tctatctgtt
     8161 tgtacatctc taatttacgc tattacggaa agcattaaca gttgtaaacg aataagagaa
     8221 gaaattgaat gcgggggagg aaaaaatgaa agtatacaaa aaattattta gttatgtccc
     8281 taaaatgaaa tactacggat ggttagccac tttattttct gatttttctg tcgtattaac
     8341 agtctatgga tattacagta tttacaaatt tcttcagtct ctaattattg taggagatga
     8401 atatttagct aagagttatg cggttcaaac tgttgcttgg ttaactttag gagctttatt
     8461 ttatattttt tctggcttat tttctcatat ccttgggttt cgcttagaga ctaatttgag
     8521 aaaaaaggga attagcggtt taacagaagc aagttttcgt ttttttgatt taaattcttc
     8581 gggatatatt cgaaagacaa ttgatgacaa cgcggctaaa acacatatgg caattgctca
     8641 cttgattcca gatagtgctc aagccatagt aacacctgtt ttatcagttg ccttaggctt
     8701 tttcattaac tttaaaattg gattggttct aatcgccatg ttagtaattg gtgtattctt
     8761 gttaaagaaa atgacagaga atacaaattt tattcaaaaa tatcaagaat cgttagatgt
     8821 gttaagctct gaaacggtag aatatatccg cggaattcaa gttataaaga tatttggtgc
     8881 taaagtaaca tcatttaaag ccttgaataa agcaattaac gattatgcta agtttgcata
     8941 taagtattct ttgagtggga aaacaccttt tgttcttttt caatggctat tttttggcat
     9001 agtttgcatt ttgatagttc ctataacctt ttttataact tctcttacca ctcccaagat
     9061 attagctgtt gacttgttga tgttgttttt tttaagtgga attatttttg tttctttcat
     9121 gagaataatg tatgtaagta tgcacttgtt tgaagcaaga tatgcagtcg aaacactaga
     9181 ctccctttat ttagaaatga agcaagacca actaaaatat gggaacgaga cacagattaa
     9241 aaattgtgac attgcatttg aaaatgtcag cttttcatac aaagaagagt gtgttttaga
     9301 aaatttcaac ttagttttag aacaaaaaag aatttatgca ttagtaggaa aatcaggaag
     9361 cggaaagagt acgatagcta aactaatttc aggtttctac aatgtggata agggacagat
     9421 taaaattggt ggtaagcctt taaatcacta ttcaaaagac acaattatta acacaattgc
     9481 ttttgtcttt caagatacga aactattcaa tcagagtatt tacgataacg tttctatagc
     9541 aaatcctcaa gcgccagcaa gtaaagtatt tgacgcgcta agattagccg gttgcgaatc
     9601 gattttagaa aaatttcccg aaagagagca taccttaatt ggtagtaaag gagtttatct
     9661 gtcaggagga gaaaaacaac gtatagctat tgccagagca attttaaaag atgcaaagat
     9721 tgttattatg gatgaagcca gtgcatctat tgatccagat aatgagtatg aactacaaaa
     9781 ggcttttcaa tatttgatga aagaaaaaac agttattatg atagctcatc gattatccag
     9841 cattaaatct gtagatgaaa ttcttgtctt gtcagaagga aaaatagtag aacgtggaaa
     9901 tcataatgaa ttaatggcta aacatcgagt gtataaacaa ttggtcacta attatgagaa
     9961 tgcaaatgat tggaggcttg acaatgaaaa atttttataa aaaaaaattt gctttaactg
    10021 atcagggcgc agaagcttta actaaagctt ctatttctag tttttttgta tactgcatta
    10081 atatggtacc agcattcatt ataatgatgc tgatagacga attagtttta gaaaatgcaa
    10141 agccccgttg gctttatttt gcagtatcgt ttgttacttt gcttttcatg tattggttgt
    10201 tagataggga gtatgaaaac ttatataata gtacttataa agaaagtgcg catttaagag
    10261 tgcaaattgc agacgatttg tcaaatttac cattatccta tttttcaaaa cataatttat
    10321 cagatttatc tcaaactatc atgtctgacg ttgaaggtat tgagcatgcg atgagtcatg
    10381 caatacctaa agccggcggt atggctctgt ttttcccttt tatttcagtg atgcttttgg
    10441 ttggtaatgt cacaatggga ttagctgtta ttttgccaac gttatttagt tttgtcttaa
    10501 tcttgttatc aaagaaatcc caaacgaaag ccaatactaa atattacgat actttgagag
    10561 aaaactcgga agaatttcaa gaaactattg aattgcagca agagattaat agctttaatc
    10621 tatctaaaaa agttcaagac agacttttca aaaaaatgga agagagtgaa aggattcatt
    10681 taaaggtaga attaagtact ttttcagtca tggccttatc ctctattttc tcatatgtta
    10741 gtttagcagt agtcattcta gtaggtgttc acttactgtt aacgggtgaa gtgactatac
    10801 tctacgtcgt tggttactta ctagccgcaa taaaaataaa ggattccttc gattctatga
    10861 aagaagcagt gcttgaaata ttttatttag ctcctaaaat acagcgaatt agagctatga
    10921 aggaaaccag tatccaagag ggatcagata gtcctctgaa atcttttgac attgagttgc
    10981 gagatgtctc tttctcatat gataacaata ccccaatttt agatcatatc tcttttacgg
    11041 ctaaacaagg agaagtgact gcgttagtag gtgctagtgg ttccgggaaa actagtatct
    11101 tgaaattagt gtctagactg tatgattatg atgaaggctg tattttaatt gatgggtatg
    11161 atattaaacg tgtatctcca gcttctttgt ttagcaaaat cgctattgtt tttcaagagg
    11221 taactttgtt taatacaagt attttggaaa atatacgtat tggaaatagt caagcgtcag
    11281 atgaggaagt gaaaaaagca gctcgtttag ctaactgcga agactttatt gaaaaactac
    11341 ctgacggtta tcatacattg gtcggagaaa acggaagttc actttctgga ggagagcgac
    11401 aacgcctatc catagcacgg gcttttttga aaaatgcgcc aattttaatt ttagatgaaa
    11461 ttactgccag tttagatgcg gaaaatgaaa aacgtattca ggaaagttta aatcgtttaa
    11521 tacaagataa gacagtacta attatatcgc atcgcttgaa gtctattgaa aaggtaaata
    11581 aaattgtagt gatggatcaa ggaaaactag ttgatcaagg tactcataat gagttgtatc
    11641 gaaggtcaga aatatacaaa aatctcataa agaaaactaa actatctgag aaattcgtct
    11701 atgaaaaaga agctcaatca cgatgatgaa ataggcttta aattaaccta caatttttgg
    11761 gatatagtta taattctttt tcaaaaagaa taattttatt aaacagcatc taattttgaa
    11821 tacacgaaag aatcagtatg attgaattag ttcacttaat gtctattctt ataatataag
    11881 gaataatcaa agttttaaaa aattggcgat aaaccagtta aacataaaag attgaataaa
    11941 aagttatagt ttctttcata ttgccgtttt aagtagagga aaagctactt aaaacggtat
    12001 ttgtgtttga ttggactaat aaaagtgaat tcttattttt cagagcctaa actgcatatt
    12061 cttttaaatg atttgattat ctctatgtac cgataaattc gttttcaaat agttatctat
    12121 tcatatgagt tttatttcat gttatttatt gttgacaaga gcaactcttg ttgataaagt
    12181 atcagtgtca aaacgtaacg attacgattt gaggtgtcta aatcaaaata aaaggagtat
    12241 aaaggtatat ggcaaaaaag tcgaaaattg ctaaagcaaa gaaacaaatg gcgatgattg
    12301 aaaagtatgc agataaacgt caggaattaa aagccgcagg agatcgcacc gctctcgcta
    12361 aattgccaag agattcaaat ccgaatcgtc tgaggcttcg tgatcagacg gatggtcgtc
    12421 caagagggta tatgcgaaag ttcggtatgt cccgtattaa gtttagagaa cttgcccatc
    12481 aagggttgat tcctggagta aaaaaagcaa gttggtaaaa ggaggaaata tcatggcagt
    12541 accagcaaga aaaacatcta aggcgaagaa acggttaaga agaactcatc aaactgtagt
    12601 aaaaccagaa atttcatttg acgaagcgaa tggtgattat agacgtagcc atcatgtatc
    12661 tttaaaaggg tactataatg gaaagaaagt aattaaagga gcttcaaaat agtttaatat
    12721 ataactttta ggagggaatc aaaatggaaa ttatttaccc acctttagtt gaagaaggat
    12781 taaagtatta tcttgaaacg acccagcaat cgctagataa atgcactttt tatcgttcga
    12841 tggtagagag aggaattatt actgaaacgg gtttaccgac ccaacaggca attgaaaatg
    12901 gattagtcaa agattactat gaggaccaag gcttatcatt tgatgatttt ttaagaatct
    12961 atccaatttt tgaagagtat gacgaggagt tatttcaatg tatcgatggt tattgggaga
    13021 tacctgttga tatgaaagaa aatttagttt cacaattgga atctggcgag ttaacttttg
    13081 aagatgcaca acaaattcaa gcatatcttg aagatcgata agtattgaag gaggaagatt
    13141 tatgcgtcaa aatattattt tggaatgtgt cgaaactgga gaacgtctgt atctcaccag
    13201 caaaaataaa cggaataacc ctgaacggtt agaattaaaa aagtattcgc caaaattgcg
    13261 cagacgggca atttttaaag aagtgaaata gctaagtggt aaaaaggtga caaaatgggc
    13321 ataccagtta caatcgtttc tgggttttta ggggctggaa aaacaacgct aatcaatcaa
    13381 gccttgcaag tctcacccta ccccagggaa gaaattatta taattgaaaa tgagtttggt
    13441 gaagttggga ttgatcacaa attattagtt catagcgagg aacgggtgtt acaactaaat
    13501 aatggatgta tgtgttgcag tcttcgcagt gatttattag caatattgat ttctttactg
    13561 gaaacaatag aagaacatca acaaccaatt tcacaaatca tcattgaaac tacaggtata
    13621 gcagatcccc aaccaatcat tcaaacactt ttaacagcgc ctcaactaag aggaagagta
    13681 tatatcgata gtttattgac tgttattgat agtgacagtt ttgaacttat tgaaagagaa
    13741 ccacaagccc ttaagcaact tgtcatggca gatcgcattt ttgtgtctag aaaacaaaac
    13801 ttgaatttat ctgcactaaa aaaattacag agagaaatca aaagtattaa ccctttatcc
    13861 gatattcgaa tgttcacaca tagtgaaacg attcaaaaaa aggattttta taatttgaaa
    13921 aaatttaatc atcccttagt ttttgaaagt gattcatcag aaaatcacta taatggcaaa
    13981 tactatcatc aacaccatca agtacatgag tttaaatcaa ttctcttaac ttcagatcaa
    14041 gacataaaaa aagatttttt actccaatgg attgactggc tgattttaac caaccaaggg
    14101 agcctgtatc gttttaaagg attgattgct ttacaagagc aggattttat agttgccatg
    14161 caagaggtaa acgaacaggt taattttcaa tacaccactc gacaaaaaga ccaaaccact
    14221 attattctaa tcggaaaaat gttggatgaa gaaaggatca aacagagttt tgataaatta
    14281 ctggcggaaa gcaaataatg ataagtagtg attgggggta atttctaatg gagaaaacgg
    14341 atatatctag tgcatatcga cgacttaaaa gcccgaatat taaaactaga aaaagggcat
    14401 taaaaattat caaagaacat aaacgaaata aaatgaagaa attagcataa ttaaggaagg
    14461 aaaaagaatg aagaaaatca gtgtaggact tattgggata gcagctctag gattattggg
    14521 agcttgctcc agcactaatg atgcaaaagt atcgaatgat aaagatggaa aattagaaat
    14581 tgtaacaaca ttctatccaa tgtatgattt caccaaaaac atcatcggcg atgaagcgaa
    14641 cgtggattta atggttccag cgggatcaga acctcatgac tatgagccct cagctaagga
    14701 tatggcaaaa gctcatgatg ctgatgtttt tgtatatcat aacgaaaaca tggaatcatg
    14761 ggtaccaaaa gctaaagaaa gttggaagaa agctgggcct aatgtagtag aaggaacaaa
    14821 agacatgatt ttattgccag gtagtgaaga agaagatcat gatcacggag aagaagatca
    14881 ccatcatgaa ctagatcctc atacgtgggt ttcacccaaa atggcaatta aggaagtttc
    14941 aaatatcaag gatcagttag ttaaattgta tccgaaaaaa gcaaaagtat ttgagacaaa
    15001 tgctgaaaag tatttgacta aactgaaacg gttggatgct gactatacca ctagtcttaa
    15061 agaagcgaaa caaaaaagtt ttgtgacgca acacgcagcc tttggatatt tagctttgga
    15121 ttatggattg aaacaagttc ctattgctgg actaagtcct gaagaagagc catcttctgg
    15181 tcgattagct gaattaaaag agtatgttaa aaaaaataag atcaattata tttactttga
    15241 aaagaatgct aatgataaaa ttgcaaaaac tttggccaac gaagctggga taaaattgga
    15301 agtactgaat cctcttgaaa gtcttacaaa agaacaaatg gataatggtg aagattatgt
    15361 ttcagtaatg gaagacaatc taaaagcgtt agaaaaaaca actatggttg ctggtgaaga
    15421 ggtagttcca gaaaaagaag cgaaggatga aaagacagtt gctaatgggt actttaaaga
    15481 tgccgatgtg aaggatcgcg aattgagtga ttatacaggc gaatggcaat ctgtttatcc
    15541 gttgttaaaa gatggaattt tggatgaagt tttcgattac aaagcaaaaa tcaataaaga
    15601 catgacagct gccgagtaca aagattatta tactactggc tataagacag atattgatac
    15661 tatcaacatt aaagacaaca ccattgattt tgtagtcaac ggtgaacatc atcaatacac
    15721 atacaaatat gttggataca aaattttgaa ttatgaaaaa ggaaaccgtg gtgttcgttt
    15781 taattttgaa actgatgatg caggtgctgg tcgttttaaa tatattcaat ttagtgatca
    15841 tggaattgca ccaagtaagg cagagcattt ccatattttc tttggtggag aaagtcaaga
    15901 aaaactctat aatgaaatgc ataattggcc tactttctat ccagcttcat tgtctaaaca
    15961 tgaaattgct caagaaatga tggctcatta aaatccaatt tttggaggaa atacatggta
    16021 agaaaagtat tattgtctat ggattccaag aatattgatg cttatcggcg ttatcgattt
    16081 gcaaagcaaa tgagattaaa tgggagtaca ttagctgata ttgctgcaac tttacatgtt
    16141 agtattgaca cagttcatag agtattaaaa cgggatcctg attgttgttt tatcaaggtc
    16201 aatactggaa gaagtagacg tttagcaaaa cggcataata gcttggccaa ttaattgata
    16261 ataccagagt agatcatttt tcccttattt ggatttgatc tgctttttat tatgtcttga
    16321 attgtcaaat caagcgcaac actttatcaa agaagacttc ataaggtgtt ctccaatcta
    16381 aacactttct aggtctgtta ttcagttttt caatcatctg atttatcgtt gagttatcta
    16441 ccgtagctat ctctttcgat tttggcaagt attctcgaat gagtctattc gtattttaat
    16501 ttgttcattg ttgccaaggg catgaggatc tggaaaataa aagggcatat tattcaatgc
    16561 ttctgtaact gcgaaatgat tggagaattc ttttcctcta tctggagtga tcgttttgac
    16621 cgcctcattt ggaatactgc ttaaaagttc aatcattttc tcgctcacat aagcggcttt
    16681 ctttctgggg accttctttc ctgctaaaag gaagcatgat tttctgtctg tcaaagtcac
    16741 taaacaagta ccaccagttt tgccagctac aatatcggct ttccaatgac caaaatcact
    16801 tctatcatct gcggattttg gacggccatg gatcgaatga gtaaggcaaa tctttccacg
    16861 agactcgaca tgattttttg tatgtcttgt ttttcctcga tggtgcaatg aacggatcag
    16921 gcctttattg ccgtgtgaga ggggttctgt atcgaaaaga tcattgcaaa ttgcacgtta
    16981 gatcgtgata aaactaattg aaaagtccat atgttcatgc ttcaaacgat tcgagatttc
    17041 ctctggcgac cactgaaaat cgacaaataa atgacgaaca attgaccaaa ctcacggatc
    17101 atttagaatg tgataacgtc cgcatttttt tcttcgataa gcataatttt tttccgcttt
    17161 ggaaggtgaa tagttttttt cttgtttctt ctcagttcat gtaaaatagt aaacgggcta
    17221 tgctgaatgt cgttgccaat tatactaata gaaaatcctt cttcgtgaag cagaaagatt
    17281 ctttctcgtt cgagtatagt aagatgacga tactggctca taattatttt ccttctagga
    17341 gtgttctcga caaacttata ctagttggat atcgattatg actcattttt atgtgttgca
    17401 cttaaagtgt aaattcaagg tatagaaaga ggttccctat gaaaaaaata cctattacaa
    17461 tcttaactgg ctatcttggt tcaggaaaaa cgatacttct aaatcatatt ctgtacggtg
    17521 atcacggaaa ggaaattgct gtcattgtaa atgacatagg ggaagtaaat gttgatgggg
    17581 tattagtcga caagaaaggt tttaaaagaa ctggagaaaa acttgtttcg atgccgaatg
    17641 gatgcatttg ttgtacatta cgcgaagatt tgattgttga actagatcaa ttagtgcaat
    17701 tttctgactt gaatcaaatt gttattgaag cttcaggaat cagcaaacca attccaatta
    17761 ttcaagcaat tatattagct aaaaaccctt tagacattga tttgacccaa cgattagaga
    17821 ttggtgccat tattatagta gtggatgtaa aacgtttttg ggataatttc gaaacgggtg
    17881 aaaagattca ggaaagaaaa gctgaaggta atgtagttga agaagaacag gatattcgtg
    17941 gcttgttaat tgatcaattc gagtgttgta acatattact tttaaataat agtgacttag
    18001 tgtcaaccaa gacgatttac aaaattaacg gtctaattgc taagttacag tccaatgcca
    18061 aaataattag gacaattaaa ggtgaagtag acttatcgaa aattctaaat acaaatcttt
    18121 ttaatataga tgagacttcc tattcagtgg gctggttcaa agagttagag cttggctatc
    18181 aaaatcatat tcctgaaaca gaagaatatg gtatctcaag ttttatctat cgaaatcggt
    18241 tactccttga cgcacaaaaa tttgcccatc ttacggataa aaattttcct ggcaatatta
    18301 caagagcaaa agggtttctt tggtttgccc aacatagtga tttttcgacg atctttgaaa
    18361 catcgggtag ctataaaagt attgaatcat taaattattg ggtagctagt ttacctaaaa
    18421 ttgagtgtca aatgattata caaaaaaatc ccgaattgaa ggaagcctgg catccgttgt
    18481 ttggtgaacg cattaataaa ctagttttta ttggtatgaa gatggatcaa caatgtatta
    18541 aggaacaact tgagggttgt ttaactgatt ctcttaatgc agataatttc cgaaaaattt
    18601 caccatttcc atggaaaaag tctaatatgt ttagccagat atcgttaatg aaatttttaa
    18661 gaaaagctgg tgtcaagata ggcgatgtca taattattgg cattttgatt attacctctt
    18721 ttattccctt atttgtattc tctatagaaa aggagaatga aacaactgaa gatgctatca
    18781 aatatgccat cgttcgaatt gatggcaagg aaatggatcg cttcgatttg gataagatca
    18841 atcataaact cgtgaattat catcctgcga agggacaata taatattgtt gagattaaag
    18901 atggaagaat tcgagttaaa gaagataata gtcctgatca aatcgcggtt agaactggat
    18961 ggatctcaaa acccggtcaa acgagtattt gtttacccca taagttagtt attagtattg
    19021 agaaaaaaga aagcacagat tactacattt actaatctgg aaatagatga ggaggttttt
    19081 aataagaaaa agatattatt attaataata gcaggggctt tattaagtgt gttaagcgct
    19141 tgtggacaag aaaaagaagc ggtgacaaca ggcacaagta tctttaacgg gacctgcaat
    19201 ggtttagtta acagtcggtt agattactta ttttggctct tcgtcaatga gtgttggtga
    19261 agaaattcaa tagaataatc gagatactca cacggctaga cagctatctt gtctagccgt
    19321 gttgttgttc tggctttagt cagttgggta gtattcttag ttttcttaaa atattttcct
    19381 cgatataaaa agattcgttc tcggtagttt tgaaagtttc taaagccata ggcaattcgt
    19441 tttagtactt tgatatggtt attcaaacat tctatagggc cgttggaata gggaacgcgc
    19501 aacgctcgtt tgatttctgt ttggtatttc ttgaaggtcg tgaacactgg ttggtagtgc
    19561 tctggcaact ccttgtagtc ttcttttagg agcgcgacga attttggaac agcttgtctt
    19621 ctaatagcgg aaagaaaatc ctggtagact tcgtagcctc gctttaagga gtcatcataa
    19681 gataatagcc gatcgactat ctccgcttct gtcagatgat ctcgaaatga cggacgccag
    19741 tagcgatgct ggcccttcaa ttcccacgca ttcttttgaa gtagtctcca gtatttcttt
    19801 aagtgcttcg accgacgatc ccttttttta aaggtcttca ttacttgaat tcggtgattg
    19861 gtaaaggccc gatcgatgtg ttggctaata tgaaagcgat cggcgacgat tcgggcattc
    19921 ggaaaacgct ctttcaccaa tgtgcgatag ggtgtataga aatctgaaac cactagacgt
    19981 acttgttcac ggacttttct agggtagcgc aagaaatagc cgcgtaaagg attgagttgc
    20041 cgattttcca caatatcaat cagttgatag gtcttgccgt ccatcatgac aaagctcatg
    20101 gctcccgaga catttttcac tgatttgaat tcatcgaaac acaccacttc tggtaacagc
    20161 tggttcaaag aaatggtttt aggccgaagg ctgcgaagta ttcgaatgac agtggtcgga
    20221 gaaatgtgct tcatacgtgc gatcaaagac atagaaagag gttcgcttaa tagctcaaga
    20281 atggcttgtt tgactctgcg agcaatggag cagcgacgat cactaactga atcttctgct
    20341 aaaaaagtct ttccacagtg tttacatttg aagcgctgtt tgttaatccg cagaatggtc
    20401 ttgtagttac tgacatcatt caataagatg gatacttttt tccagcccta tttaatgatc
    20461 gtttgttcat tttgatagtg gcgatgaaag cattcctccg gttgataggt caatgtgcca
    20521 tcaaaagcaa aacatgtttc gtcattgatg cgctctttgc gaaaggcatc ttcatgaaag
    20581 gtaagattta ggtctagaat atctagtaac tctttggtaa actctgaata ggacatcttg
    20641 aaacactact ttgaatggtt tttgtcgact ttattctaaa ggattttaag gtgtctgttt
    20701 gcgtttatta gaaaaaagaa aaagtattgg caacagaagg cgtcaccaac actagatatt
    20761 atagatccct tattttcttc gcttcaaatt gtcaaggagt catcataaat tttgtatgga
    20821 ttcttttgtt tgggtagtag tcttctaaat aattttggat taacaccttc atctctattt
    20881 tacttttata tttgttggag tcgattaatt ctcatttgat tgatcgatga aacgcttcaa
    20941 ttactgcatt gtcaacagga gtcccagttt ggctcactga atgtgtgatg tggtggtcgt
    21001 tcaacagctc ttgataaata aaagaccgat gctggctacc tctatcggaa tgaattaccg
    21061 taggcaattc tccttaataa atttgtaatg gacggacgac aatctctttt ttcatgtgtg
    21121 aatctaccat atagtaacgt agaatacgag ttgctaagtc aatataggtg gacaaataga
    21181 ggcgaccgtc attacatgga atgtaagtaa tatccatcac ccaaacagca tcaatttggt
    21241 tctgttcaaa ttatcgattc aacatttttt taccatttct ttgattgttt tttctctacc
    21301 atgagaagat ttgcgtcgat gaaatcctct tgtgcataaa ttcatttcac gcataagaac
    21361 agctacaaca cgtttattga tttcgattcc ttcatcgtaa agtttttgag tgatccctgg
    21421 agatccgtat cgatctttgt gttcgtagaa cactcgtctt cctcttttag tcgtttattt
    21481 tcctgttcaa gaatgtagaa atctgcttta tcaggtaatc tttttccttg tccagcaaaa
    21541 gcatttttcc cgtatcgacg atattctgaa acccatcggg aaattgctag acgagagata
    21601 ttgtattctt cagcaatttt cttggtagtt acttttttct caaggatatc ctgtgaaatc
    21661 tttagtttaa atttacgatc atatgttttt ctcaatagag ttcattcctt ccggtaacgt
    21721 aactgatagt caagaaaagt gtatcatagc ccaacttagt atcagggttt gtcaactaaa
    21781 ctgtggaagt tgatagataa gagtttttaa caaccaaaat tctcttgact atttttgaaa
    21841 tcagacaaat tttgattgga cacatagttg aataaatcta ccgtcgttac ggaaggtaaa
    21901 tcgcatgctt ttcaattcta gaggagaagt cctcgttgaa gtaccatagc ccagttctgg
    21961 attcgacctc ctgcccactt catacgtaaa taaagtaatt ttaggagtga gactgtgaca
    22021 aaagttattt ttaagctaaa aacgaattaa aaaacgttga taattaaaat cattcgtttt
    22081 agattctatg aatcattata gaacgctgta aaatcgatac tttataatta taaagaagat
    22141 agtttcaaat ttattgttcg aaatttgaaa ctatcttttt acttatgtca cagactccct
    22201 tagttgagtt attctttaat ttcgaatttc gagatagcta gatatattgc aagcatacat
    22261 tcttgataac aatcttgatc atattttcca gttctccagg attgcttatg aatcaaagag
    22321 ctaaatcttt tgagaattgc ctcaacagct tcttcatttc cagcctttgc taaaatgaaa
    22381 tcttctttta aagaattcat aaatctacct tcttcccatg gacttataat ctatttcttt
    22441 gggaaggagg agaacgagca aagaagcata caaaattagt tattatgcag atattaaacc
    22501 agcatttttt gaattttttt gtaaagtcga tgttttaaat ttgtcgcacc ctgtcttgta
    22561 atccccagaa cctttccaat ttctttatca gttttatcaa agataaattt ttcgataaga
    22621 aaaatttgtt caggttcttt caacaaagga aggatttttg ctaattttat atcttcaaca
    22681 aggagagtca catttaaaac attaatcggt tgtttaaatt ttatagtatc tttagtaaac
    22741 aaatatggtg ggagttgatc aagttgttca tgtttttgaa tttcttcttg ttttttataa
    22801 taagtattag cggtgttcaa aatgaccttt tcaaagaatc gaatcaactg ggcatttacg
    22861 cgttcgtcgt tatctgacat attgcacacc tcctccatta agatttaaag ggaaaagagg
    22921 caaaaaacac gaaaagaagc taatgcaatt atgctgcgct gcgaataact tctataagct
    22981 cacatgcatt gataggactg ctgatgttta ttttcaaaaa tgttttttta gttgat
//
LOCUS       DAJSMK010000039        22883 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.040, whole genome shotgun sequence.
ACCESSION   DAJSMK010000039 DAJSMK010000000
VERSION     DAJSMK010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22883)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22883)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22883
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.040"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            55..609
                     /locus_tag="ON488_001496"
     CDS             55..609
                     /locus_tag="ON488_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR3231696.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(782..1255)
                     /locus_tag="ON488_001497"
     CDS             complement(782..1255)
                     /locus_tag="ON488_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR3231697.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            1267..1803
                     /locus_tag="ON488_001498"
     CDS             1267..1803
                     /locus_tag="ON488_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3231698.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            1843..2214
                     /locus_tag="ON488_001499"
     CDS             1843..2214
                     /locus_tag="ON488_001499"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3231699.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            2498..3769
                     /locus_tag="ON488_001500"
     CDS             2498..3769
                     /locus_tag="ON488_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCR3231700.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            4014..5039
                     /locus_tag="ON488_001501"
     CDS             4014..5039
                     /locus_tag="ON488_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3231701.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            5333..6442
                     /locus_tag="ON488_001502"
     CDS             5333..6442
                     /locus_tag="ON488_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCR3231702.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            6525..7421
                     /locus_tag="ON488_001503"
                     /pseudo
     CDS             6525..7421
                     /locus_tag="ON488_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648409.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            7437..8261
                     /locus_tag="ON488_001504"
     CDS             7437..8261
                     /locus_tag="ON488_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3231703.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            8293..9603
                     /locus_tag="ON488_001505"
     CDS             8293..9603
                     /locus_tag="ON488_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HCR3231704.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            9751..11010
                     /locus_tag="ON488_001506"
     CDS             9751..11010
                     /locus_tag="ON488_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCR3231705.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            11020..11892
                     /locus_tag="ON488_001507"
     CDS             11020..11892
                     /locus_tag="ON488_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3231706.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            11904..12734
                     /locus_tag="ON488_001508"
     CDS             11904..12734
                     /locus_tag="ON488_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3231707.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            12774..14957
                     /locus_tag="ON488_001509"
     CDS             12774..14957
                     /locus_tag="ON488_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCR3231708.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDETVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            15018..16238
                     /locus_tag="ON488_001510"
     CDS             15018..16238
                     /locus_tag="ON488_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HCR3231709.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            16235..17695
                     /gene="gtfA"
                     /locus_tag="ON488_001511"
     CDS             16235..17695
                     /gene="gtfA"
                     /locus_tag="ON488_001511"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HCR3231710.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            17772..18878
                     /locus_tag="ON488_001512"
                     /pseudo
     CDS             17772..18878
                     /locus_tag="ON488_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            19200..19409
                     /locus_tag="ON488_001513"
     CDS             19200..19409
                     /locus_tag="ON488_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCR3231711.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            19402..19551
                     /locus_tag="ON488_001514"
     CDS             19402..19551
                     /locus_tag="ON488_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HCR3231712.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            19705..20370
                     /locus_tag="ON488_001515"
     CDS             19705..20370
                     /locus_tag="ON488_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3231713.1"
                     /translation="MELREIRPIDIQKWQNNLLSKYKNSYVRNMYGIFQMSLDRAVVL
                     GLLEKNPAKVIGNVKKRKTTVDFWTKEEFTKVISTFYIDDLYQHFGFICMWLLFMTVM
                     RLGEATALTWKDIDFENKNLRVNKTLYYKRAKTYEFVEPETASSIRTIELDDNTITFL
                     KAWKERQVSIGGMSFVLSYNGTPTQKYTIRHIMRRHATIVGVHIIRIHGLRHSHASLL
                     ISQ"
     gene            complement(20654..21739)
                     /gene="xerS"
                     /locus_tag="ON488_001516"
     CDS             complement(20654..21739)
                     /gene="xerS"
                     /locus_tag="ON488_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HCR3231714.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            22073..22306
                     /locus_tag="ON488_001517"
     CDS             22073..22306
                     /locus_tag="ON488_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HCR3231715.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            22303..22710
                     /locus_tag="ON488_001518"
     CDS             22303..22710
                     /locus_tag="ON488_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCR3231716.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
BASE COUNT         7820 a         3430 c         4383 g         7250 t
ORIGIN      
        1 gtaaaatata tacataatca ttaactcaga atatttttaa gaagggaaac aatagtgagc
       61 tataatgtac aaccgttaag gacaaatgaa gagatacaag attttcagtt ttggctaaga
      121 agaacaagta atccggaaag agatagtttt ttatttttgt ttggaatcaa taatgggtta
      181 cgtatgtcag atattatagg attaaaagtt ggagatatac gaggcaaaag taagcctatt
      241 attgttgaac ataaaacagg taagcgaaaa ccgattttta tagataattt gagagaagaa
      301 attttattat atactgaagg taaagaagaa aatgattggt tatttccgag tcggcaacaa
      361 ggtcgacata taacaaggga tcgtgtctat cagatatatg cagatatagc agaaaaatta
      421 ggacgagatg atataggaac acatacatta agaaaaactt ttgggtatca ctactacaag
      481 aaaactagag acattgctac cttaatgttt atttttaatc atagctcgca agcaattaca
      541 aaaaggtaca ttggtataac tgaagatgaa ataggagcat cacttcgtgg atttaaacta
      601 ggtgtataat ttaaaaattt ttataaacag taaagacaaa gattaaaagc tatttttatc
      661 tagaacgatt ttatttcata aagttcgcgg aataaaagct ggggttactg gtacttggta
      721 taggttcgtg ttatataaac taagtaatta aataacattt ttaggttgga aaaggatgaa
      781 attaaaaaaa gagaatcaat acggtctcaa aaacgcaaac gctgcggaat aagaaaaata
      841 ctgataactc aacgtttagc agactatcta atagggatag tctgcttttt tcgtttttga
      901 ccatactttt gaccttctgc aaacttcctt gcttttcctc tgtagaactc atgaaatctg
      961 caaaacgaat tgccgtttcc tctgtctgct ttttcgcgat atgggtgtat atatcatcca
     1021 tagtggtttt aatatctgta tgtccaagtc gaacatacac ttctttgaca gacgcaccag
     1081 attcaaagag cagactacaa tgggtatgac gaaaaccatg aagtgtgata tgttttaagt
     1141 tattctcttt aatgatgatt ttcaaattgt gatttacata gtctaaataa aggggcttat
     1201 tttcttctga tgaaaacaaa agttgttcac catcttttat aggtttgatt ctcattttta
     1261 gatattatgc ccgcacgtat tcatcacatt tctattgtga atcgctttat tcgaccgaca
     1321 tttgactttt atcataatat actcggttta aaattactaa tgaaaacaat taatcaagac
     1381 gatcatacca tgtatcacct gtttttttca gataatcacc accgtgtggg aactgaactg
     1441 actttttttg aagtacaaga agggaacaac cagttttttg gaaccaatac gattgaacga
     1501 acgatactaa aagttccttc cgaagcatca ttgcattttt gggaaatata ttttgaaaca
     1561 caaggcgttt gccattatgg aatcgaatca ttttctggac gacctatctt acgttttgaa
     1621 gggccagatg caacacgatt agctttagtt cccttacgcg aatttgaaga tattgatgat
     1681 tatttcccgt atgtcacaga ccagatccct acagagcatg ccattttagg aattgatgcc
     1741 attcaactac gcgtacaata ttccgatgcg actgaacgag agttattgtc ggtaggctgg
     1801 tagcacaaag aatacgtcag tttcttttcg ggtcatcaac gagtgacaat cttagaaaat
     1861 caagacactc agttctatca agaagttcag attattcaag atcgtgagaa tccagttgcc
     1921 attgaaggga ttggtagcgt ccatcatgtt gcgtttggcg tagaaaataa atctgattta
     1981 caacgcatcg acaaacaatt acaagagcgc aattttataa attcaggaat aaaagatcgt
     2041 gaattttttg tatcacttta ttatcgtgac ccaaatcaat tattgattga aattgctaca
     2101 ggggaaggaa acctagatgc aaaagcgtat gaaaatcaaa gtccacgctt tgaagaaatt
     2161 cctttatttt taccgcagta cttaaatttc attcgtgaac aagtggagca ataattagct
     2221 aatcaaatcc atgacgaaga gtaagaggtt gactcataag tcaaaaaata aagaaaaacg
     2281 catcaaatcc attctaaaga atgttgattt gatgcggttc ctatttttat aaactatcat
     2341 tttcgactaa taaaactact tatgagtcag cctctctttt tttcttgatt tttatacctc
     2401 tttctaggta aactaaacat ctgccaaaaa taccgtgtct cattgaaaca ttctcaacta
     2461 tttcaaaata aaggggagta ccaaatgaac gagtatattg aaattatcca cgcaagagaa
     2521 acaacttaaa aatgtcagtc tcaaaattcc caaaaataaa attagtattt ttaccagcgt
     2581 atctggttca ggaaaatcat cgattgtttt tgatactatt acccaagaag ctggtcgtca
     2641 actgaatgac acctatgata gttttacccg tttattttta cctaaataca gtcgtccaga
     2701 ggttgatgag attgataatc tttctacggc gattgtggtc aatcaaaaga agattggtgg
     2761 cagtgcgcgc tcaacgttag ggacgattac taacatcaat gcgttatttc gtgtgttgtt
     2821 ttcatgtttt gcaacaccta gtttaggata tgcaaatgct tattcattta atgatcctag
     2881 tggaatgtgt tctgtctgtc agggaatcgg taagacgatt gcatttttaa taggattgct
     2941 ttatttttcg gctattgata atgctgattt tgtattttct gatccattta ccgcagaagt
     3001 tttgtctgga attgaggaac aggcaaagaa tcatggttat tttgtattgg tgcataatgt
     3061 taattcagca gaagatgtta aaactattca gagaaattgg cgttttgagg ggttcattgt
     3121 tgttggtgta cgtgtaaaag aatttttgga attaaataac gtttttgatg gtcctgttgt
     3181 ttatattgat acgcatcttt caaaagagac attaagagaa cttgaacaac aaatgaatcg
     3241 tttatttgta aatacaaatg attaccaagc tagtacattg gcagtggaac atttgattca
     3301 ttatggtcat gagaaaatag cgtttctttc ttttgactac attgtaggtg aaccaagtgt
     3361 tattcaagaa cgacatcaag cttatatcga tacattaaag aaatatcatt taacctttaa
     3421 atcgcattgg atatataaca actctgaatt tgagcgaatt tatcaagaat tagctgaatt
     3481 tactgcaatt gttgttactg gagattattt agcggctaaa ttagtaaaat ttttaaaaaa
     3541 taagaataaa cgagtgatgg aacaattatc gattattgga tttgatgata ttacttttgc
     3601 agaattaatg gatcctgcgt tgacaacaat acgactaaat ccaggtaaca agggggcgat
     3661 tgcttttcac caactgattg gactggccaa acaagaagaa ataaaaaatc aagtactact
     3721 attagaggga gaattgattt ctcgagactc tgttcacaaa atcaaataaa aaagctctgt
     3781 gaaataagta tagttaacaa taaaatatcc gaacgataga gagaatgaac tgtgatctag
     3841 cagttcctcg tcgcaaattc actagaatta gcattattta ctctaaattg ttcggatatt
     3901 ttttcttgtt tttaattatg attacagtgc ctatttttaa cgaaatttgc ttattttcaa
     3961 aatgtatgat tatatgttag taaacacttt caaatatgaa aagaggagct attatggtag
     4021 gaattaggga tgttgcaaaa cgggcgggtg tgtccattgc aacagtatcg cgcgtgctaa
     4081 atgaggatcc gacactttca gtaaccgatg aaaccaaacg aaagattgca gaatcggtta
     4141 atttttatca ttatgtcaaa aaaagtcccg ttgcaaaaaa tttaacaaat attgcattaa
     4201 taacgacagt ttctgaagta gatgagttgg aagatcccta ttttcgaacg attcgcagag
     4261 ggattcaagt cgaagcagaa caaagcaaag tcaatttgaa gaaaattatt cgtttgtcag
     4321 aaacaccgtt ggagcaagac gatttgctaa aatgtcaagg tgtgttgatt attgggcagg
     4381 tgctatcttc tgtgattgaa gaagtatcag caattaattc gaatgtcgta gtgattgatg
     4441 accctagtat tgaagctgaa gtagatgcag tttatactga tttaacaaaa gcaacgaatc
     4501 agcatttaga tcgattgtat aaaaaaggac accgaaacat tgcgtttatc ggaggaggac
     4561 gtgttcgttt agatagccaa ggaaataaac acgtgtcaga tgatgattat cgaaaaatag
     4621 cctatgagac gtggatgaaa caaaaaggat tagaaaaata tagtcaaatt tatttagaag
     4681 gctggaccac acttgacgga atgcaggcag cagatttact tttgaaaaaa catgctaaag
     4741 ataagttgcc gactgctatc atggtaggaa atgatcctat tgctgtgggg gtttatcgtt
     4801 cacttcaaaa aaatggtcta catattccag aagatatttc gattgtgagt tttgataata
     4861 ttgaagttgc tgaattttta acacctgcat taaatacggt gaatgtgaat acagaagaaa
     4921 ttggaaaact agcagttcgc atggttaatg aacgaataaa agaagttaga aatgtttcga
     4981 tcaaagtgat tgtttctaat aatattattg ttagagaaag tgaaaaaaat atcgattaaa
     5041 aaagtaaaca tccaaaaaag ggtgtttact tttttgttta ctaatatttt tagtaaaaaa
     5101 tctcgacaaa acattaagta aacagttatg gtgttgttaa caaaaagaaa acgcattcaa
     5161 aacaggagga attaagatga aacatttcaa aaaaatagct ttaacaggga tagctgtttt
     5221 aactgggaca ttactcgcag catgtggtgg gggagatagt aattctaaag acgggcaagt
     5281 aactttaagc tatgcgagtt gagatactga ccaagctcca ggactaagaa aaatgttaga
     5341 tgaatttgaa aaacaaaatc ctgatatcaa agtagaaatg gagacaacgc cttgggatca
     5401 atattgggtt aaattagaag ctgcaacaac gggaggtaat atgccagatg tagtaaccat
     5461 gcactctagc gaatcctata aatatatgtc acagaatgct ttgatgggac ttgatgatgt
     5521 tatcaaagaa aatgatattg acatgggaaa ctttactgaa ggaattgctg atttctatac
     5581 gcttgaagac gaactatacg caatccctaa agatgcttct gtagtggggc tatggtacaa
     5641 caaagaatta tttgataatg caggtgtcga ttatccagat gaaacatgga catgggaaac
     5701 actcagacaa gctgcaattg atttaacaga tgaatcaaaa ggcatctatg gttttgcatc
     5761 acatattgga acagagactg gctactggcc atttatttat caaaatgggg gagaagtatt
     5821 tgccgatgac aatacaaaat caggtttgaa taccccagaa gcacaagaag ctttagcttt
     5881 ttatcgagat attgcacttg ttgatcatgc ttcaccaaca attacagaat tacaagatcc
     5941 tgataagtta agtcgttttc aatcaggtag attagcaatg atgattgaag gaaactggtt
     6001 tgcaccggga tttttgaaaa atgactatct agttgaaaat gttgcttctg ccgtgttacc
     6061 taagggaaaa gttaatgcaa caattacaaa tggacttggt tgggctgcca gtgcgagtac
     6121 aaaataccca gaagaagtga aaaaactaat ggcattttta gctagtgagg acgccaataa
     6181 aatccaagcg gaaacggggg catcaatccc agcactaaaa ggctttgaag acgagtgggc
     6241 tgcttcttca gatacaattg atttgagtgc ttttggaaaa atgttggagt atggagtccc
     6301 tcgtccatac aataaagatg gattacgagc tgaacaagca gaagttcaaa ttattaaccg
     6361 tattctgtct ggtgaagtaa ctgttgaaga tggaaccgct caaattgaaa aagaagtcaa
     6421 tgcgatattg agcggaaatt aaattagtta attatacaat atacaggcga aaggattcta
     6481 tttcgtctgt atattaatgg atgaatacca aaaaggggga tattatgaaa aatcgaattt
     6541 ttggaaaata tcgtaaagat caagtgatat ggggctatat ttttattttt ccaacggcat
     6601 taggattaat tttattaaat atatggccag caattcaaac agcaatttta agttttcaaa
     6661 aaacggtagg gttcggtgat actgaatggg tcggattaag aaattaccaa aaaatgtttg
     6721 cagacggtga agtttttcag tctttattaa acacattaat ttatgcagtg gtttcgatac
     6781 ctagtattgt tgtattatcc ttgttggtgg cagttttaat gaatagaaaa gttaaaggat
     6841 tgtcgattta tcggacaatt tattttctac cagtcgttgc tgcaccatcc gcagtcgcaa
     6901 tgatttggcg ctggatgttc aataatgatt atggactgat taataacatg ttggctaaaa
     6961 taggtctcga tggaccagca tggttaacgg atccatcgat tgcgatttat tctattatca
     7021 ttgtaggagt ttggagtgct attggttata acatggtgtt attactagcc ggcttataag
     7081 aaattcctaa agattattat gaagcagcgg aaattgatgg tgctagtcca atccagcagt
     7141 ttttcaacat tacgttacca ttagttacac caacattatt ttttgtagtt gtaacaacag
     7201 ttatcaatgc tttccaagta tttgatgtta tttttatgat gattactcct aatagtaccg
     7261 ccatgtttaa atcacaatca ttagcctatt tattctataa acattcattt attttaaatg
     7321 acaagggata tggttcggca atcgttatgt tccttttagt gattatatta attattactg
     7381 caattcaaat gaagttgcag aaaaagtggg taaactatta aggaggctat caaattatga
     7441 aaaataaatt tttttcaaat gcgccaatcc atatcatgct tattttaggt ggtattgcaa
     7501 tggcattacc ttttatttgg atgattttaa cttcagggaa aacgttggtt gaatctaccc
     7561 aaattccacc tacaattttc cctgagaaat ttcagctaag taactatcaa caagtacttg
     7621 atttattacc attcatggct ttttatatca atacattttt aatggttgtt ggacgagtga
     7681 ttggctcggt tttattttca gcaatggctg catatgcttg tgcgcgtcta agttttccag
     7741 ggaaaaatat ccttttcagc ttagtactta ttcaaatgat gattcccggt tccattttta
     7801 ttactccaca gtatttatta gcacaaaaat tgggtatttt aaatacaatt ccagcattaa
     7861 tattaccagg ggtagttagt gcgtttggta cgtttttatt aagacaattt ttcttaggtt
     7921 tacctgatga attggaggaa gcggcctatt tagaaggtgc caatatttgg acgatctttt
     7981 tcaaaattat gttgccgctt gctaaatcag gattggttgc acttggaata ttcacagcgt
     8041 tgtttgcatt taaagattta atgtggccat tgattgtcaa tacttcaatt gataagatgc
     8101 ctttagctcc gggattagca aacttacaag gacaatatgc cacgaacttc ccacaattaa
     8161 tggcaggttc gttattagca atttggccaa tagttgtgat attcatcgtt ttccaaagaa
     8221 aattcattga aggaattgct acaacaggta gtaaattata aaactattaa ttagtgattg
     8281 gagagtaagt acatgacaaa aattacattt attggtgcag gaagtactat ttttgcaaaa
     8341 aacgtattag gcgatgcgat gttaactcca agtctacaag atgcacatat tgcattgtac
     8401 gatattgatg aaaaacgact aaaagaatca aatttaatgc ttaaaaatat taataaaaat
     8461 tcgaatgaaa atcgtgctga tattgtttct tattatgatc gcaaagaagc gttaagagag
     8521 gctgattttg ttatcaatgc tattcaagtg ggtggttata aaccttcaac agtgattgat
     8581 tttgatattc ctaaaaaata tgggttgcga caaactattg gtgacaccat ggggattggt
     8641 gggattttta gaaccctacg gacactacca gtaatgttag actttgctaa agaaatggaa
     8701 gaagtttgtc caaatgcttg gttattgaac tatacaaatc cgatggcgat gttaaccatg
     8761 ggtgttttaa aagcgacgag tattaagact gttggtttat gtcatagcgt tcaagtatgc
     8821 gtaccagaat tgtttgagca tttaggaata gccgatcaat atgacttaaa tgactttcaa
     8881 tggaaaattg caggcattaa tcatatggca ttcttgttgg aaattacaaa aaatggggaa
     8941 gatttctatc caacaattcg tcagttagct gcagaaaaac caaatccaca tccagattct
     9001 gtacgttttg aattgttgaa acgttttggt tactatatta cagaatcaag tgaacacaat
     9061 gcagaatacc atccatactt tattaaatca aaatacccag aattgattga cgaattaggg
     9121 attccgttgg atgaatactt acgtcgttgt gaacaacaaa ttaatgattg ggaaagcatg
     9181 cgagaggaca ttgtaaataa tggggagtta acacatacga gaagccgtga atatgcttca
     9241 tatatcatgg attctattac gacaggaact ccgtcagtga ttgcaggaaa tgtcttaaat
     9301 aaaggcttaa tcacaaactt accgacagat gtttgtgtgg aagtaccttg tttagtcgat
     9361 aaaaatggcg tgcaaccaac ctatgtcggt gaattgccaa cacaattagc tgctttaaat
     9421 cggacgaata tcaatgttca agaactgaca gtagaagccg ctttaacact agataaatca
     9481 aaaatttatc aagcagcgta tttagatcca catctatcat ctgaattgtc tttaacagat
     9541 atcaaaaatt tagtggatga tttaatcgaa gcacatgggg actatttacc tgaatataat
     9601 taaaaagaag ctgaaagagt aaggaatttt caattcctta ctcttttctt agttaaattt
     9661 agtaaaaata ttgacaaaac acttagtaaa cagttacatt agtgttaaca aaaagaaaac
     9721 gcattcaaat tgtataagga ggagcataaa atgaagtggt ctaaaaaaat tattttagct
     9781 tgtatagcac taggagcaac gatctctttg actgcttgtg gaaaaaatca ggaagatgca
     9841 agcggtaagg tagaaataga gttttttaat caaaaaaaag aaatgactca aacgattcag
     9901 gagattgcta aagattttga agcaaaaaac cctgatattc atgtaaaagt tgtggatgta
     9961 ccgaatgctg gtgaagtaat taaaacacgt atgcttgcag gcgatgtacc agatgtcatt
    10021 aatctttatc ctcaaagtat agaattgaaa gaatgggcga aagctggtta tttagaggac
    10081 ttaaccgaag aaccgtattt agagaatatc aaaaatggat atgcacaacg ttttgctatt
    10141 gaggatcgtg tatatagcat accattaacc gctaatgtct atggttttta ctataacaaa
    10201 actgcttttg aggaaatggg gattcaagca ccagaaactt gggcagaatt tgaaaaaata
    10261 gtagctgaga ttaaagatca aaacaaagta ccgtttgcga ttgcaggagc agaaggctgg
    10321 actttaaatg gttatcacca actagctata gcgactgctg ctggtggtga agaggaagcg
    10381 aacaatgttt ggcgtttctc agaagttaat ggaattaatg ctgaaagcaa agaaatgcaa
    10441 aaagatttta atcgattaga tttgttaaga gaaccaaaag ctttgcaaaa caactggcaa
    10501 ggtgccggtt ataacgatac agtagttact tttacaaaag gtgatgcgtt gattatgccg
    10561 aatggttcat gggcaatgcc gatgattcat tcacaaaatc cagattttga agtaggaact
    10621 tttccttttc cagcagatga agcaggtcaa agtctaacga ttggcgcagg agacctagcc
    10681 ttatcagttt ctgcaacttc tcaacataaa gaagaagcca aacgttttgt agaatatatg
    10741 acaacacctg aagcgatgca gaaatattat gatgtagatg gtgcaccgtg tgctgttgag
    10801 ggcgttatcg agaatactca ggattcacca ttaagtggtt taactgaact tgcttttact
    10861 gatcgtcatt tagtttggtt agccaaagat tggaatagtg aaaatgattt ttatacctta
    10921 acaacaaatt atttacacaa tggcaatcaa aaagccatga ttaacgcatt aaatgctttc
    10981 tttaatccaa tgaaagctga cggaaggtag gaaaataaaa tgaaaataaa agaaatttta
    11041 aatcgttact gggcaatcat ttttgtagca attccaatta ttttgcagat gatttttttc
    11101 tactttccaa tggttcaagg tgctttttac agtttaacta attggactgg tctgacttat
    11161 aattttgatt ttgtgggttt gaacaattat aagattcttt tttctgatcc gaagtttatc
    11221 aaatcgattg gcttcacttt aattgtgacg ctttgcatga ttgctggaca aattggtttt
    11281 ggtattttga ttgcgcgggc gttgaacgca aatattaaag ggaaaacatt ctttagagca
    11341 tggttctttt ttccagcggt cttatcgggc gtggttgttt ctttagtatt taaacaaatt
    11401 tttaactatg gtttaccaaa aattggtagt atgttaggca ttgaattttt acaaaccagt
    11461 cttttaggaa caacatgggg agcgattttt gcagtaattt ttgttttact ttggcaagga
    11521 attgccatgc cagtcatcat tttcttagcg ggttttcaaa gtattccaca agaaattatt
    11581 gaagctgcta gaatggatgg ggcgaatgat aagcaaattt tttggaatat tgaaatcacc
    11641 tacttattac caagtatttc aatggtattt attatggcat taaaaggtgg cttaacagca
    11701 tttgatcaaa tttttgcttt aactggtggt ggaccaagcg atgccacaac atctttgggg
    11761 ttacttgttt ataattatgc ttttaaaaac aatcagtttg gttatgcgaa tgctattgct
    11821 ttagtcttat ttatcttaat tgggattgtt tcactggcac aattaaaatt atcgaaaaaa
    11881 tttgaaatct aggaggtttc ccaatgaaaa catcaaaaga aaaaaatatt tctaaatact
    11941 tgcttttatt attagggggc ttcatgattt tagttccctt agtttcaacg ctattcggtt
    12001 catttaaaac aacacccgat attatgaata atttctttcg ttttcctaat ccagcgactt
    12061 tggaaaattt ccgaagattg ttagcggatg gaattggtca ttacttttgg aattcggcaa
    12121 tcatcacaat cattgcagta gttgctgtga cagcaattat tcctatggct gcttattcac
    12181 tagcaagaaa aatgactcgt gggaaagcat acggattgat gtatttattt ttaattttag
    12241 gaatttttgt tcctttccaa gtaattatga ttccgattac cgttatgatg agtaaaattg
    12301 gtttagcaaa tatgtgggga ttaatcttac tctatctcac ttatgccgta ccacagacac
    12361 tatttttata tgttggtttt attaaactaa atgtgcctat cagtctggat gaggctgctg
    12421 aaattgatgg ggctagtcac tttacaactt atttcaaaat tgttttccca atgttaaaac
    12481 caatgcatgc gacgactatt attcttaatg ctctatggtt ttggaatgat ttcatgctac
    12541 cattattaat tttaaatcgt gattctaata tgtggacact accattgttt caatataatt
    12601 atacgggaca atattttaac gactatggtc caagttttgc ttcctataca gtaggaattg
    12661 tcacgattac actagtttat cttgctttcc aaagaagtat tatagctgga atgagcaatg
    12721 gagcagtgaa ataaccaata aattattctc attataaagg agttcataaa cttatgatta
    12781 tatttgacaa tcacacacaa acatttcatt tacaaaataa aaaaattagc tatctattag
    12841 gaatcgaaga aaataattat ttaacgcatc tttattttgg aaaaaagatt acgcactatt
    12901 ctggtgggta tcgctacccc cgaacagatc gttccttctc acccaacaat gcaaatgcgc
    12961 aagatcgttt attatcttta gacacattac cattagaatt tccaggatat ggacatggtg
    13021 attttagaga accggcgcat aatattaaat taggaaacgg tagtcgtgta aatgattttc
    13081 gttatgatag ctacgaaatt caaaaaggaa agcccagctt agcgggattg ccagccttat
    13141 atacggaaga tgatgatgaa gctgaaacgc tgattattca attgaaagac gcgattagtg
    13201 gattgacttt acagttgttc tacacaattt atcaaaatca cagtgtaatt attcgttcta
    13261 cgcaattagt aaataatagt gatgaaacag tggagattaa ccgcttagct agtcaatcaa
    13321 ttgattttcc aaatcgtcca ctcgagttaa ttcatttaaa tggtacctgg gcaagagaac
    13381 gtcaaatgac tagagaaaaa attcatacag ggataaaagt attagatagt aaacgcggat
    13441 caagcagcca tcaacaaaat ccgtttgttg ctttagtaga tgccaaaaca gatgaatttc
    13501 aaggagaggc atatggattt aatttagttt atagcggtaa tcacgaaacg gtgattcaaa
    13561 aagatccatt tgaccaaaca cgggtcatta tgggaattaa ttcatttaat tttggttggc
    13621 aactaaaaac tggcgactca tttcaaacgc cagaagtcgt gatggtttat agtaatgaag
    13681 gtctgaatac gttatcacag acgtatcatg aattgtataa tcaccgttta attcgtggaa
    13741 actatcgttt aaaagaacgt cccacgttaa tcaacaactg ggaagcaacg tattttgatt
    13801 ttaacgaaga aaaaatcatg aatattgtcg atgatgcgaa gaacttgggc attgaaatgt
    13861 ttgttttaga tgatggttgg tttggcggtc gtgaaaatga cttcacttca ttaggtgatt
    13921 gggttgaaac agaaggcaaa cttgcttgtg gtttggaaaa tttagccaag caagtgcatg
    13981 ataacgggat gaaatttggg atttggtttg aaccggaaat gatttctgaa gatagtgaac
    14041 tatttcgagc acatccagat tgggcattgg gtattccagg tcgtgaccgc tcaattagtc
    14101 gaaatcaata tgttcttgat ttttcaagac aagatgttcg tgataatatc tatcaacaaa
    14161 tgacggcgat ttttgatcgt gtaccgattg attatgtgaa gtgggatatg aatcgaaata
    14221 tgacagaagt ctattctgtc ttgttggact caacgatgca aggtgaagtg gctcatcgtt
    14281 atatgttagg gttatatgaa tttttagaaa agttaacaac gaattatcca actattttat
    14341 ttgaaagttg ttcgggtgga ggcggtcgtt ttgatgcagg tttcttgtat tacatgccac
    14401 aaacttggac gagcgacaat accgatgccg tggctcgtct gaaaattcaa tatggaacca
    14461 gcttagtgta tccaatttca agtatgggtg cgcatgtttc agcagtccca aatcatcaaa
    14521 caggaagaga aacgagttta actattcgtg gcaatgctgc gatggctggt gtttttggtt
    14581 atgagctaga tctaacgcaa ttaacttctg aagaaaaagc agaaattaaa gaacaagttg
    14641 ccttttataa aaagcatcgc caacttttgc aatatggaac tttttatcgc ttggaaagtc
    14701 cgtttgaagg caatgatact gcatggatgt ttgtctcaaa agaccaaaca gaagccatgg
    14761 tcttttattt ccgagtatta gcagaagctg cgcatccatt agtcacattg aaattagcag
    14821 gattagcaga agaagcaact tatcaaatgg aagatgtaac atttgctggc gatgaattga
    14881 tgaatctcgg tttttatatt gactcagaac tacatggtga ttatgcgaca caacgctttt
    14941 atttgaaaca gatatagtag cttgaattta caatataagt gcaacaccaa aagagactca
    15001 ttccaaacga agaaaatatg ttttatttac acgcatttac taaaaagcag cctgatttga
    15061 attgggaaaa tgaagaagta cgtgaagaaa tctatgcaat gattaactat tggttagata
    15121 aaggactagg cggatttaga atcgatgcga tattaaacat caaaaaaaaa ctagagtatg
    15181 gcatctttga atctgatgga gaagatgggt tagccttcat tgggccctgg attcttaatc
    15241 agtcgggcat tgaagtgtgg ttaaaagaaa tgagagagcg gacatttaaa ccacataata
    15301 gtatgacggt agcagaagcc gatgttccta atgaacgttt agatgaatat attggtgaag
    15361 atggctatta ttcgatggtt tttgatttta gttatacgga tattgatgta cctgaaactg
    15421 gtgaatggtt taaagatagc caatggacat ggacggatat gcgtaccaat atttttacga
    15481 atcaattagt tacgcaagat aaaggttggg gcgccttata tttagaaaac cacgatcaac
    15541 cacgttcaat taataaatat attccagaag aatggatcaa tgattatagt aaaaaaatgt
    15601 tggcgacgct ttttatgtta ctaagaggta ccccttttat ttatcaagga caagaactag
    15661 gaatgaccaa catagaaatg gcatcattag aagattttga tgatgtagct acgcattctc
    15721 agtataaacg ggcattagaa tatggattgg caccagagca agcattgaaa gctgtcaata
    15781 aacgaagtcg ggataattct cgcacaccta tgcaatggaa tacgcaaaaa aatgccagat
    15841 tctcaacttc tgataatgta tggttaaaag taaatcctaa ttatccagaa ctcaatgcag
    15901 aagctcagtt aaccaatcaa cagtcggtat tcaattatta tcatcaatta attaaattaa
    15961 gaaaaaatag tgtatacaaa gacgtgctaa tctacggaca atttctacca gtgaaagata
    16021 aaaatgaaca tattttgctt tatgaacgcc aattagaaga taaaatcgta ttagttatct
    16081 taaacgttac agcaacagaa caagaatatt atgtagatga acagtaccaa caagtattaa
    16141 tcaataatta tgaagatgtt ttattagatc aaagtcgaaa attgcgttta cgaccgtttg
    16201 aaagtattgt attagctaat tatggaggac aattatgaaa attaaaaacg aagcaatgct
    16261 catcacctat gcagatagtt taggaaaaaa catgggcgaa ttaaaacaag tcttagacaa
    16321 acatttacaa ggtgttattg gtggtgtaca tctgttgcct ttttttccat cgacaggtga
    16381 tcgaggcttt gcgccgagtg attatacgac agttgatcca gctcttggaa catgggaaga
    16441 tgtggaagca ttaggtgaag attattattt gatgtttgat tttatgatta atcacatttc
    16501 tcgtgaatca aaatttttcc aagatttcaa aaaaaaccat gagcagtcac catacaaaga
    16561 aatgtttatc cgtattcatg aatttttccc agaaaatcga ccaacacaag aagatattga
    16621 tttaatctac aagcgtaaag acaaagcgcc gtttcaaacg gtagaatttg cggatggtac
    16681 gacagaagag gtttggaata cctttgggga agaacaaatt gatttagatg tgaccaaaga
    16741 agttgtgaaa gaatttattc gagaaaccat caaagatatg gcgaaccatg gctgttcttt
    16801 aattcgatta gatgcgtttg cttatgcgat taaaaaatta gataccaatg atttcttcgt
    16861 ggaaccagat atttgggaac ttttagacga agtgcgtcaa gaagcagcga aatatgacgt
    16921 cgaattatta ccagaaatcc atgagcatta ttccattcaa atgaaaattg ccaatcatga
    16981 ttattatatc tatgacttcg ccttgccaat ggtcactctg tattcacttt atagtggaaa
    17041 atcagaacgt ttagccaatt ggttgaaaat gagtccgatg aagcagttta caacattgga
    17101 tacgcatgat ggaattggtg ttgtggacgc tcgtgattta ttaacagatg aagaattgga
    17161 ttacacctct gaggaattgt ataaagtcgg ggcgaatgtg aagaaggtct attcaagtgc
    17221 caattacaat aatttagata tttatcaaat taacagcacc tattatagtg cattaggcga
    17281 taatgaccgt agctatctgt tagcacgtgc gattcaagta tttgcgccag ggattccaca
    17341 aatttattac gttgggttat tagcaggaaa aaatgatatt gaactgttgg aagcaacgaa
    17401 agaagggcgt aatattaatc gtcattacta tgatttagcc gaaattgaag aagaagtgca
    17461 acggccagtg attcaacaat tatttgcact tttaaaattt agaaatgaat ctgcggcgtt
    17521 tgatttggat ggaacgattg aagtagcaac gccatcagaa tcagaaatag tgattacacg
    17581 taaaaataaa aacggtagtg atagtgcaac attaacggct aacttggata cgaaagaatt
    17641 tatcattgag tctaaagata taaaaatttt cactagtgtt gcattaaaat tttaacctat
    17701 tccatagaac aaaaaatcct ttatactagc acttggatga cttatccaag accaataaaa
    17761 aggactcata catggataag tataaaacaa atacagcatt taataaatgg ttttctgcca
    17821 taaaattagg aaaactttct gtcaactccc aaaaatgtat ttttgattac aattcgtatc
    17881 gtaaaaaact gtcttttgaa gctgtgctca agctctttct ctacgcagtt aatgaagaaa
    17941 aagaaagttt gcgtgatttg agtacagctc ttatcgaccg atcgctccaa ctagaaaccg
    18001 atgtgtcatc gattagtcat acccaattgt ctcgagcatt taatgcactt gaacctaaag
    18061 tgttagaaga aatttttcaa caactgttag aaaaagttca acatcaaatc aaaccaacca
    18121 agcgaaatca tctgtatctg attgattcca gtacgttttc gcttagttta aaacgtcata
    18181 agtgggcgac tttccgtcaa acaaaatcag gtgtcaagtt acacttaaac tattgttata
    18241 tggacgatac tacgatgtat ccaactgatt ttaccttaac aaatgcccat gaacatgatc
    18301 tcaatcaact accagtattg gtgaatcaac cagaggcaac ttacgtgttt gatcgtgggt
    18361 attaggactt tgaaaagatg gatcagatgc attgggatgg ctatttcttc gtcactcgga
    18421 ttaaaaaaaa caccaaagtt cacgtgatag atactctgga aacatcgcca gaaacagaaa
    18481 ttctacgaga cgagctggtt cgtttaggat ctaaaaccta tctaaccgcc aatttccgac
    18541 tagtcactgt tcaagataag aacggacgtg tgtttcaatt tatcaccaat cgaatggacg
    18601 tctcttcaaa agaaatctct gatatgtatc acgctcgttg gcaaatcgaa ttgtttttca
    18661 agcacatcaa acaacacatg accattaaaa ccttcttttc tcaaagtgaa aaaggcgtgc
    18721 agaatcaatt gattttaacg atgatttccg ctctcctcac gtttctcatc aaattggaga
    18781 cgaaaacgga aaaatcagtg ttccaaatca aacgattctt tcgttattta ctgtttcagc
    18841 cctttgaatg ttgtctagaa aaattaattc ccacatgaga aaaaagaaat ttggctcgtt
    18901 acttttggtt ttcagttgaa taacagataa aaaattttct ggaaaaagtc atcctctgcg
    18961 tcagcacagt tttttttgac ttattttcag aggaaatagt tttcagaata ttctaaaatg
    19021 ttttatgcaa cactagtgat attttttaga attagatttc taatgtgcat tttttgagta
    19081 ttaaggagca agtatacaaa gatttataaa gctgattaaa tttgaataaa aatatgcagg
    19141 aacgctacta tttttagtag tgttcttttt tatatttgaa taaaaaatgt ggtggttaaa
    19201 tggtggttat aacaaaaaat gaattaatga aattaggtta tgggaagtat cagtctgaga
    19261 gaatcatacg acaggcaaaa gcaattatgg tttcaaaaag ctatacctat tacgaaaata
    19321 gaagattagg actagtacct gttgaatctg tagaagaagt tttaggtatg aagatagagg
    19381 tagaggagga ttttcagaat catggttaat tttaaaaaag ataaaaatgg gaaatatcat
    19441 tttactgcta gtttgggatt cgacaaacga acagggaaaa gagtacaaaa aaacgtagag
    19501 gggttaaaac agttaaagaa gaaaaaaagc gtataccgaa cttgtttcta attatggaaa
    19561 agaagcagaa acttctcaaa gtactatgtt gtttgaggag tttttttata aattattcct
    19621 accttattat caagggaaag tagaagaaag aacatataaa aatcggttat ctacaatcaa
    19681 aaaaactttt cttatttctt taaaatggag ttaagagaaa tacgtccaat tgacattcaa
    19741 aagtggcaaa ataatttatt gagcaaatat aaaaattctt atgtaagaaa catgtatggg
    19801 atttttcaga tgtcattaga tcgagcagtt gttttgggac tacttgaaaa aaatcctgca
    19861 aaagttattg gaaatgtgaa gaaaaggaaa actacagttg atttttggac aaaagaagaa
    19921 tttacaaaag ttatttcaac tttttatatt gatgatttgt accaacattt tggttttatt
    19981 tgtatgtggt tactttttat gaccgttatg cgtttgggag aagccactgc attaacttgg
    20041 aaagatattg attttgaaaa taaaaacttg cgtgtgaata aaacactcta ttataagaga
    20101 gccaaaacct atgagtttgt agaacccgaa acggcttcta gtattcgtac aatcgaacta
    20161 gacgacaata caattacctt tttaaaagct tggaaggagc gtcaagtttc aataggaggc
    20221 atgtcgtttg tactttctta taatggaaca cctactcaga aatatacaat ccgtcatatt
    20281 atgagaagac atgcaacgat cgttggtgtt catataatcc gcatacacgg attaaggcat
    20341 agtcatgctt ctttgcttat atcacaataa aaagatgcac ttcgaattaa agaaaggtta
    20401 aaacatgctg atgtacaaac gactttagga acttatggtc atttgtatct aaattcattg
    20461 agagagataa caaatgatcc cacagattat atccaaacta atttttctaa aatcaaaccg
    20521 acacctattt acgataataa aaaataaatg ataaacaaaa gtaggatcac accaaaagaa
    20581 acacactaga aaaactataa tacaggcttt tctagcgtgt tgtttcttat ttccgcctat
    20641 ttatacatta tactcataaa gcatttaatg catcgatcgt agccgcattg tctatatggg
    20701 tatataaagt tgttgtattg gtacttgaat gtcccaattg ttgggcagtt aataccaatg
    20761 aatttgtctg ttggtagagt ctagtagcta atgtatgacg cagtttgtga gggctgactt
    20821 gaattctaaa gccttttgaa tattttgcta ccatccgttc gattgcaata ccggatatac
    20881 gcttggcttc tccttggtaa attgctagaa ataaagcttt ttcgttttct gttactttat
    20941 atcgttcttt ccgaatagct agataattag ctaaatattc cattgcgaat gctgctatat
    21001 tgacagcatc tcttttattt ccttttctag ttactaccac attattctta tctaaagata
    21061 ggtcatctaa attaatattt ataacctcgg agagtctcaa tccagatcct aaaatcagtg
    21121 cattgatcgc caggtctctt tctacatctc gttgataata gatcaaagct cgtttactca
    21181 aagtattttt atattcattg gcaatataat ctagataatt ttgtgtatcc ttatctagaa
    21241 ataatttttt ctcaatggca ttggcacgtg cagctaacgt agttttatct gtgatggttg
    21301 ctacttgatc cataggatta ttgtctaagt atggttttcc tagaggatta ttggaacttt
    21361 tcgaaagata tttaaataga acctttaatg ccgtgatatt tctattgata gtagaagtag
    21421 atagacctaa gttattatta tctttgagct tagtttttgt tgtctctttt tttacatttt
    21481 cttttgtgcg acgtttcaaa tgagatttgt acaagtttag gtcataggca gttaactgtc
    21541 ttatcgaggt gatagaagta tcaggaacga tagactcact cagaagccat tcataaaaga
    21601 gcttataatt ttttagatat tctaaagtgg ttcgaggtga ttgatcttta tcctcacgat
    21661 cttgaacaaa atcttttata taatcgggca tatgaagtat gattgtatct attttttgat
    21721 atatttctgt atttttcatg tcattcatcc tttcaataag taggggagaa gagtatctct
    21781 ataattggac tataccaatt atagaatgtt ttgtcaattg gtatgctcta aaatttatta
    21841 atttgtttca aaaaaagcat ataaacaggt atacgtttaa taatttaaaa taaatggtat
    21901 acataaatag ggaaggaaat agaagggagc aatctaaatt ttttgaattt tcttaattaa
    21961 ttatatagaa agaacaatct ttctatagag ttagacatga gagggactat gcttgattta
    22021 aaatcaacaa gcgtatatac tgtatataca aagaaaaagg agggagaaga ctatggcaat
    22081 taaagaaaga aaatttaggg aagtggggaa ctcagtagta ttaactattt caaaggagtt
    22141 tcttaaagaa aatgggttaa atcccggaga tacggttttt ttagatgaag aaaaacttcg
    22201 agcggcaatt acaaaaaaac aagccttatc tgatgaaatt gatttagcaa tatctcaagc
    22261 attaactgaa tatgatacta cttttagaga gcttgtcgat aaatgagtat tcattaccta
    22321 gaagccaaag atattataaa aatgaatgta atccaaataa aaaaatactc tcctaatgaa
    22381 ccccttggtg taaaggatgc gaatgcttta gaaatgtgtg tagggcaact tcgagcctca
    22441 gcttttggtg aagaggttta tccttcgatt tatgaaaaag cagctatcct acttatacaa
    22501 ttgataaaga aacatccttt tcacaatgca aataaacgta ctgctttctt agctactttt
    22561 gtctttttga aaatcaatgg acagctttta gctattgatc aaaaagatgc tgtaaattta
    22621 gcggtatata ttgctacgta tgataaggat ttcgatcaac taaaatatga agtgatcaac
    22681 actataaaga cacatacgca gcccatttaa ggagttactg tatgtgtctt tatagggtta
    22741 ttagctgcta tagcgaaata attgaagtaa attacaaata gctataattc aaatccaact
    22801 atatagaaaa cgtaaatttt ctatatagtt ggattaagat aacgactatt tattttatca
    22861 tatttttact ataccctata ctt
//
LOCUS       DAJSMK010000040        21644 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.041, whole genome shotgun sequence.
ACCESSION   DAJSMK010000040 DAJSMK010000000
VERSION     DAJSMK010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.041"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            144..542
                     /locus_tag="ON488_001519"
     CDS             144..542
                     /locus_tag="ON488_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HCR3231717.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="ON488_001520"
     CDS             526..1221
                     /locus_tag="ON488_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HCR3231718.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1805..2692)
                     /locus_tag="ON488_001521"
     CDS             complement(1805..2692)
                     /locus_tag="ON488_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCR3231719.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2877..3716
                     /locus_tag="ON488_001522"
     CDS             2877..3716
                     /locus_tag="ON488_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCR3231720.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3912..4886
                     /gene="sgrA"
                     /locus_tag="ON488_001523"
     CDS             3912..4886
                     /gene="sgrA"
                     /locus_tag="ON488_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HCR3231721.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5184..5540
                     /locus_tag="ON488_001524"
     CDS             5184..5540
                     /locus_tag="ON488_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231722.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5543..6700
                     /locus_tag="ON488_001525"
     CDS             5543..6700
                     /locus_tag="ON488_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231723.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6726..7166)
                     /locus_tag="ON488_001526"
     CDS             complement(6726..7166)
                     /locus_tag="ON488_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCR3231724.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7326..7832
                     /locus_tag="ON488_001527"
     CDS             7326..7832
                     /locus_tag="ON488_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCR3231725.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8000..9913
                     /locus_tag="ON488_001528"
     CDS             8000..9913
                     /locus_tag="ON488_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HCR3231726.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9918..10919
                     /locus_tag="ON488_001529"
     CDS             9918..10919
                     /locus_tag="ON488_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3231727.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11121..11327)
                     /locus_tag="ON488_001530"
     CDS             complement(11121..11327)
                     /locus_tag="ON488_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HCR3231728.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11973..12821)
                     /locus_tag="ON488_001531"
     CDS             complement(11973..12821)
                     /locus_tag="ON488_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR3231729.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12820..13887
                     /gene="gnd"
                     /locus_tag="ON488_001532"
     CDS             12820..13887
                     /gene="gnd"
                     /locus_tag="ON488_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HCR3231730.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13889..14890
                     /locus_tag="ON488_001533"
     CDS             13889..14890
                     /locus_tag="ON488_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HCR3231731.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14887..15171
                     /locus_tag="ON488_001534"
     CDS             14887..15171
                     /locus_tag="ON488_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HCR3231732.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15204..16001
                     /locus_tag="ON488_001535"
     CDS             15204..16001
                     /locus_tag="ON488_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCR3231733.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16015..16848
                     /locus_tag="ON488_001536"
     CDS             16015..16848
                     /locus_tag="ON488_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3231734.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16866..17723
                     /locus_tag="ON488_001537"
     CDS             16866..17723
                     /locus_tag="ON488_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCR3231735.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17745..18254
                     /locus_tag="ON488_001538"
     CDS             17745..18254
                     /locus_tag="ON488_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3231736.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18291..18692
                     /locus_tag="ON488_001539"
     CDS             18291..18692
                     /locus_tag="ON488_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231737.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18804..19157
                     /locus_tag="ON488_001540"
     CDS             18804..19157
                     /locus_tag="ON488_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231738.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19191..19634
                     /locus_tag="ON488_001541"
     CDS             19191..19634
                     /locus_tag="ON488_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCR3231739.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19651..20736
                     /gene="uxuA"
                     /locus_tag="ON488_001542"
     CDS             19651..20736
                     /gene="uxuA"
                     /locus_tag="ON488_001542"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HCR3231740.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20729..21442
                     /locus_tag="ON488_001543"
     CDS             20729..21442
                     /locus_tag="ON488_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCR3231741.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7458 a         3323 c         4509 g         6354 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 ttatttctca tttaaacgat gtattcccta acctctaata catccttgta actctgaagt
     1381 tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata aaaatatctt
     1441 tcgtgtttct ctagtataac agaataagag gaacaagtcc agaagggata tttttagtct
     1501 tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg aagcgatacg
     1561 gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg attcatgtga
     1621 tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc agtgatttgt
     1681 tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt gcctcaaaaa
     1741 taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat tgggtcaaat
     1801 ttgtttattt gaatatattt tttacataag gatctttaat agttacattg tcttttttca
     1861 tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct tcggtagcaa
     1921 ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt ttttttacca
     1981 tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga atgatatcag
     2041 aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga atctctggat
     2101 tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt tttccataag
     2161 cttgaacaag cttggagaaa ttttcccctt catttgcttc tttttttgct ttatctgctt
     2221 cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat tctttccaag
     2281 cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat tggaaagcca
     2341 gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct tttaattgtt
     2401 ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt acttcctttg
     2461 aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt ttttttaata
     2521 gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact gtaagtgttc
     2581 cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat agtaaaattg
     2641 cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc atcctttcct
     2701 tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg taaggttgct
     2761 gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat ttacatagtt
     2821 ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga tgaaagatga
     2881 tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt gttttaggaa
     2941 ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg attggagcaa
     3001 ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt gctagtaagg
     3061 tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac tgggggtatt
     3121 tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt ccattatatt
     3181 tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg ataacgagtt
     3241 ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc ttttttcagc
     3301 atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca ttatttgctc
     3361 ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc tttttagcag
     3421 gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct attggtgctc
     3481 atattacttg gaattggaca caaggagcta ttttgggtat accagtcagc ggaacgcaag
     3541 aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact gggggaaact
     3601 ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt gttggtttgt
     3661 tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat caataaaaga
     3721 tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga ttaaacgaaa
     3781 aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca actgactgtc
     3841 gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta attatatgga
     3901 gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg ctgagtataa
     3961 ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag aatctttcat
     4021 ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt actattccag
     4081 tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca tatggttggg
     4141 atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac gtacaatgga
     4201 ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat gagatcaaga
     4261 gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc acggagaatt
     4321 tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc acaagtagtg
     4381 aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc agtgaaagta
     4441 gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa agtagcacag
     4501 gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc acaggaagca
     4561 tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga aaagtaaata
     4621 atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat gcagggagca
     4681 acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat catcaagaaa
     4741 aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt agaaccttga
     4801 acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca agctattttc
     4861 gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa ttgaataaaa
     4921 cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc gaagttgtag
     4981 ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata acaggaacac
     5041 aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta gtatctctga
     5101 aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata agtctaaata
     5161 atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat gaaaggcaag
     5221 tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg gtgaaggata
     5281 tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa caagcagaat
     5341 cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac aagatgataa
     5401 aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt ttagagggaa
     5461 cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc ttagaaaatc
     5521 ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag aacttaatac
     5581 tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga tagaaggaga
     5641 agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg acgaaaatca
     5701 ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat ttgcgaaaca
     5761 tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa gaatttcgtt
     5821 gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga acaaatttgt
     5881 gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt tttttgaagc
     5941 aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt attttatgtt
     6001 tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata aagtacaaga
     6061 aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact tcaagatttg
     6121 ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc atttgtattc
     6181 aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag aagacagaga
     6241 ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta gtggggtagc
     6301 tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga tttttcaata
     6361 ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat tctatattca
     6421 atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat ctatgactga
     6481 acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca ttagcgatta
     6541 tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact ggaatggaca
     6601 acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca ggaatgagaa
     6661 aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga ttgtttatgc
     6721 caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg accagaaagc
     6781 aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct gattttatct
     6841 tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt tttcaataaa
     6901 gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc tattctgtga
     6961 acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc gttgtttgtc
     7021 aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa gttctgttcg
     7081 ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga cgagcagcca
     7141 gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt tatgaaataa
     7201 taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa aatgttgtca
     7261 cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag aaagaaggca
     7321 caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa ggggtatgtt
     7381 ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat aaaagaatca
     7441 aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat gctcaattag
     7501 tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag cacagttatt
     7561 ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt ttattaactg
     7621 aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt atagatacga
     7681 ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga gcaacgacaa
     7741 cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag aaaatttggg
     7801 ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa aaaagcagaa
     7861 tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat cctgttctat
     7921 ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac atataattct
     7981 cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa agggagcgtt
     8041 ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg gagagagcat
     8101 ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg ctggaaatga
     8161 aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg agacatctgt
     8221 tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag aagaagcaac
     8281 agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca aagagaatgg
     8341 gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat atttgaatta
     8401 cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca agtcaaaatt
     8461 aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata aagagattat
     8521 caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa acagtgtgtt
     8581 gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca caggcttcta
     8641 tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca aaatgatgga
     8701 tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc atggcggatt
     8761 tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt ataaggccgg
     8821 gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg attatgtgac
     8881 ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag ttcgagagcg
     8941 gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga tgatgtctgt
     9001 attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg gatttgcatc
     9061 aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac taccggatgc
     9121 cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat ttatgggcct
     9181 tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg ctctacctac
     9241 gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag atgatgtagt
     9301 acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag atcttttatt
     9361 agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct acacgaaaca
     9421 tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt atgtggatga
     9481 aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag cttatggaga
     9541 aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg ttgaaggacc
     9601 gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca aaaaaatccc
     9661 agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg gaaagaatga
     9721 acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag tgaaagtaca
     9781 aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga aacattcgct
     9841 tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga tttggcgaag
     9901 aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta ccagttatca
     9961 tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag ccgattagct
    10021 tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc cgaccagatg
    10081 atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat ccttcaaagt
    10141 acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa ttaccgattc
    10201 ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt cgtgattatt
    10261 tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat gaacgatcac
    10321 cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa gcagctaaaa
    10381 aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat tcggcaggtg
    10441 cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa aaagctgatc
    10501 atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg tctggtctgt
    10561 tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt tatgaaaaat
    10621 gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc aaaagtttag
    10681 ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat ggaaatacaa
    10741 atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg ggggtgaaag
    10801 tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat cagtttgatt
    10861 tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc aaggagtaaa
    10921 gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca aggagcaatt
    10981 tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag gagttagaga
    11041 tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg tcacgatctc
    11101 ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa agcaacaaat
    11161 ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa gaatgctggt
    11221 tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat agcaaataaa
    11281 atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag cagcacctcc
    11341 ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag tttgttagga
    11401 tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat aagcaattaa
    11461 tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca ataatagaaa
    11521 atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc caaaaattcg
    11581 atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa taaaattaca
    11641 aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt aattcaccaa
    11701 aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag aaaagataaa
    11761 ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg aataatacca
    11821 atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta ttgatgttct
    11881 gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg ctttttttgt
    11941 tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga aatagtatgt
    12001 cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa aatcacatat
    12061 agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga tcggaattct
    12121 gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga agaattagct
    12181 tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc aatatggatt
    12241 gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc cgtcaataaa
    12301 gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat aggggaacgc
    12361 aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc gaaaaaatag
    12421 acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg ttgtaacaac
    12481 ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc catagtgagc
    12541 tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc attttcttgg
    12601 atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt tgtaaattga
    12661 aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg actatgactt
    12721 actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg gctgaagtcg
    12781 ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc tcattttcat
    12841 aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag agtaggaaaa
    12901 aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt gtataatgag
    12961 ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg aaaaatggga
    13021 ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact cgacatttca
    13081 agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga gatctctgaa
    13141 tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc tggagagata
    13201 accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat tattattgaa
    13261 ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca gaaaaatgaa
    13321 atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca tcaagcctgc
    13381 ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt caaagatgta
    13441 gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt cttgaaaatg
    13501 atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt ccaacttgta
    13561 caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa tcatggttcg
    13621 gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca tcccaattta
    13681 agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aatggacggt tgaaacagcg
    13741 ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag gaatctttca
    13801 caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg gtttggcgga
    13861 catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa tcgttaattc
    13921 cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag ttggagacgt
    13981 tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt tacttaaagg
    14041 attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt ttgaaaacaa
    14101 agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg atttaaaagc
    14161 agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac gaaatgctgt
    14221 agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac aagcacaagc
    14281 aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga cgctgtttaa
    14341 caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg aaattttgcg
    14401 taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt tatacatcga
    14461 aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag atatcatttg
    14521 tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag aagtcgatca
    14581 gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg atgaagaagc
    14641 gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg ttttagaaga
    14701 agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga ttacgccaca
    14761 tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg tcagagatgt
    14821 cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga gcaactatat
    14881 aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc tcaattttat
    14941 ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata cggcgcgaaa
    15001 agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa attagtattt
    15061 ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg tagttatgct
    15121 gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta gttggcgttg
    15181 gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga atcgatttcg
    15241 gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct gtcatgtata
    15301 aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct gcttttttta
    15361 taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc gggttagcag
    15421 atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt ttgcaagatg
    15481 aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag attttgaatc
    15541 attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag ttcaaacagc
    15601 tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat aaatacgcaa
    15661 gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg gaaagccatc
    15721 gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca ctagaaggtc
    15781 gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg ccggtttctc
    15841 tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg gctgaattta
    15901 ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa tcactgatac
    15961 agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg acacatggaa
    16021 acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt tatgtcccgc
    16081 tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac tggattagtc
    16141 gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc tttgcaaatg
    16201 atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc tattgcagca
    16261 gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc gattgccgtt
    16321 gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt catcaatact
    16381 tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc tatggcccga
    16441 tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct tgttttcatt
    16501 gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga gggaacagtc
    16561 gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat cgcgacaact
    16621 gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta ttttatgagt
    16681 gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg gattattatc
    16741 gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac aagcaataac
    16801 aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt taggaggaat
    16861 gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc acgaaaaaag
    16921 atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac tcttttgaac
    16981 gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa ctttataaag
    17041 atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac actcaattaa
    17101 gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa agagcagaag
    17161 aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac acgaaagcgg
    17221 gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc gtccaatata
    17281 tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc gcactttttc
    17341 cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca agacaagctt
    17401 tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag acagcgattg
    17461 aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac tatgtaaaag
    17521 tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag gaaattcttg
    17581 atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac ttgttctata
    17641 cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata ttaattgtgc
    17701 tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt gtagtcaatt
    17761 tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta tctcaaaaaa
    17821 gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa tttatgagag
    17881 atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt acaccagaga
    17941 aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt ttgatcgcaa
    18001 aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa gaattgaata
    18061 ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa tctgtttatt
    18121 taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc gtaaagaata
    18181 tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta ttgaacaagt
    18241 ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa atgaagaaga
    18301 acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag cgccgtacaa
    18361 aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt atgagaacag
    18421 atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt tatgttggag
    18481 atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt catgcattag
    18541 gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac tctatattat
    18601 tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat aacaaaaatc
    18661 ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta gcatttggga
    18721 gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa acttttattc
    18781 gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat gatccgagtg
    18841 tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac agcgtgagat
    18901 cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca gatacaccgc
    18961 tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa gttgataagt
    19021 tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg cagttcttct
    19081 atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc aatcagatta
    19141 ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta atgttggaaa
    19201 tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg gaagtaattg
    19261 tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac atccaaacat
    19321 tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc atgctagtat
    19381 ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc aatgaactga
    19441 ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca atgttgttag
    19501 aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa caaattgtca
    19561 aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa aaattagatg
    19621 aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg gtatggtgaa
    19681 aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa tgggataatt
    19741 ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat tgaggagttg
    19801 aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt agcgatccac
    19861 gatgcaatca aggcagggac agatgaacga gattactata ttgataacta tatacgaaca
    19921 atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa accaattttt
    19981 ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc tcttttatac
    20041 gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat acacagccag
    20101 tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt cgctcagctg
    20161 gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac ttatttttta
    20221 gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca tccagatgat
    20281 ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga cttgaagaaa
    20341 attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg atctttaggg
    20401 gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg catccatttt
    20461 gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac ggcacatccc
    20521 tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca agaagggttc
    20581 gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc tatgcctgga
    20641 tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata tgaggcgata
    20701 agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca tctttgatat
    20761 ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa aatcagcaca
    20821 aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc aaacagaaat
    20881 ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata tcaaatggcg
    20941 agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag tatatacgaa
    21001 aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata caatcgtggc
    21061 ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc tatatgcctt
    21121 gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac cagagatctt
    21181 tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat ttgaagactc
    21241 gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca tcaaagatca
    21301 tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg taagtttata
    21361 tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac gatttttaga
    21421 aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt atttattgtc
    21481 ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag tatctacctt
    21541 atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct accagtagat
    21601 gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tcca
//
LOCUS       DAJSMK010000041        20853 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.043, whole genome shotgun sequence.
ACCESSION   DAJSMK010000041 DAJSMK010000000
VERSION     DAJSMK010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20853
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.043"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(10..846)
                     /locus_tag="ON488_001544"
     CDS             complement(10..846)
                     /locus_tag="ON488_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3231742.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(843..1712)
                     /locus_tag="ON488_001545"
     CDS             complement(843..1712)
                     /locus_tag="ON488_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3231743.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(1782..3065)
                     /locus_tag="ON488_001546"
     CDS             complement(1782..3065)
                     /locus_tag="ON488_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCR3231744.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(3079..4764)
                     /locus_tag="ON488_001547"
     CDS             complement(3079..4764)
                     /locus_tag="ON488_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HCR3231745.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            5039..6064
                     /locus_tag="ON488_001548"
     CDS             5039..6064
                     /locus_tag="ON488_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3231746.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(6659..10333)
                     /gene="rpoC"
                     /locus_tag="ON488_001549"
     CDS             complement(6659..10333)
                     /gene="rpoC"
                     /locus_tag="ON488_001549"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HCR3231747.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(10391..14008)
                     /gene="rpoB"
                     /locus_tag="ON488_001550"
     CDS             complement(10391..14008)
                     /gene="rpoB"
                     /locus_tag="ON488_001550"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCR3231748.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            14736..15704
                     /locus_tag="ON488_001551"
     CDS             14736..15704
                     /locus_tag="ON488_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3231749.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            15722..16627
                     /locus_tag="ON488_001552"
     CDS             15722..16627
                     /locus_tag="ON488_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3231750.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            16624..17430
                     /locus_tag="ON488_001553"
     CDS             16624..17430
                     /locus_tag="ON488_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3231751.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            17566..18555
                     /locus_tag="ON488_001554"
     CDS             17566..18555
                     /locus_tag="ON488_001554"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HCR3231752.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(18872..19396)
                     /locus_tag="ON488_001555"
     CDS             complement(18872..19396)
                     /locus_tag="ON488_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HCR3231753.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            19683..>20853
                     /gene="scm"
                     /locus_tag="ON488_001556"
     CDS             19683..>20853
                     /gene="scm"
                     /locus_tag="ON488_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCR3231754.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDST"
BASE COUNT         6094 a         4416 c         3930 g         6413 t
ORIGIN      
        1 cttttctttt tatcctttta cgccgccttc gactaaatca cctttaataa atcgttcaga
       61 taacgcatac ataatgatga ctggtaaagc ggtcaccaat gaagcggcca tcattcgtcc
      121 ccaaatgtag tctggtgtac tgaataatgt gttcaaaccg attggtaaag taaatttttc
      181 ggaggtcgac aggaaaatcg aagcaaataa ataatcattc cacgaaacca taaagcaata
      241 aacgaagaca gaaatgattc cagaaatagc caatggtata atgatccgaa taatgatctg
      301 gatccggcta agaccatcga tcattgctgc ttcttcaata tcagtcggaa tcgtgtcaaa
      361 ataacttttt agcatgaata tcgcagtagg aagtgtttga acgaccatcg tgataatcag
      421 tgctgtattg gtatcataca aacctagacc ggaaatgatt ttaaataatg gaacaacgat
      481 caaaataccg gaaaacatat aaacggtgta aaagctagca ttgattttcg agcgagcttt
      541 gaagcgtagt tttgacaaag cgtatgcccc gctgatccca atcactactg cagttacgga
      601 ggctatcaag gagatcacta aactattttt gaaatacatg atgaatggaa aaatctcagc
      661 attgaaaata tcctgataat gttcaaaagt ccattctttc ggaaaaatag tttgtgtcgt
      721 tgcaattgct tcttgtgaat ccttgaatga tgtcatcagc atgatcaaaa atggaaacaa
      781 attgacagct aatagcaaca aaatcgtcgc gtaaaataag attttcctgc tctttttatt
      841 tttcatttca agtccacctt ctttcgtgag agcaagacga ccgctgcaat aatgatgaac
      901 aatagaatcg atatagctgc tgcttttcca agatcattga acgcaaaggc tgtctgatac
      961 aaataaacgc ctaagatatt gactttattc gtcagtagat agacatctgt aaacatatag
     1021 aacatccaga tagatcgtaa aacaatcaca gttgctagta ctggtttgat tgccggcagt
     1081 gtcacgatct tgaacttctg ccaagcattt gcaccgtcca tttcagctgc ttcataaagc
     1141 gttttgtcga ctgtttgcaa aatagccaaa aatgaaataa acgcatacgg atagtatctc
     1201 cagatagcaa acaaaacgac cataaagaag ctagcaactg gctggtcgaa ccacagcggt
     1261 gcttcgttga aaagctgcaa cctatctact aacagatcat tgacgattcc ataactatta
     1321 ttgaacatat atttccaagc aaaaatcaaa gaaatagatg gcgtaacata acttaataaa
     1381 atcagtgaac gcaccgtttt cctaaatctg aacttgcggt taagcaaaat agctacggct
     1441 aatcctaaag ctgtactgcc tgctacaact aagaatgtgt aagcaactgt taaacctaaa
     1501 gaacgataaa attcactatc acttaaaatt tcaagataat tgcttaatcc gataaaaacg
     1561 gcgtctgagt taggattcag cggcatatcg aaaaaactga tctgaatatt ggaaagcatt
     1621 ggaatcagca ctaaaacagc taataaaagc atgcttggtg ctaaaagtcc catggctaat
     1681 tttaagtcag aatgtttcct tggacgattc attgaaacct ccccctgata atctgccaat
     1741 agctatctac ttttttcgaa caccattggc agaacttctt gttatttcgt atttttttgt
     1801 gcgtcagcta aagcttgatc gacatcttcg tttccgacag ttacttggtt cactgctttt
     1861 ccgatcacac ctgagcttgt gatatctccc attttcgtga aattcttttc cccgactagt
     1921 ccaaagactt gtacttcatc aaaagcacta gcaatctcag atggcagctc gccaaaagac
     1981 ttgatgactt cattttcttt gtaaccatcc agttcgacta cttgtttatt cactggttga
     2041 gcaccaccag gagacatcaa gacccacttt tccatgtttt tcggttgaga taagaaagct
     2101 gtgaatgctt cagcagcctc tttttgtttc tcgtctagac cagaagaaat cgtcaatcca
     2161 gatactgtgc catagacagc ttgatctttt tgtgttggga tagcaaaacc gatattttct
     2221 gagttccccg cttcataaac agaaggcaaa atgtaagttg aatagattgc cattggtgct
     2281 gttccattca tgaaagcatc tttgatttct gtcacatcat tagagcctgg catcgtgtat
     2341 tgggataagt tttgataaaa cgacaatgct tctctcatct tttccgtatc gatcgttacc
     2401 tcgccttcat catccaaaac atttgctcca tttgacaaag caaattgaga gaacgcttgc
     2461 tcactcattg ttccttcagc agtaggcata gcaattccat attgtttatt ctctttatct
     2521 gtgaaatgtt gagcaatttt taaaatatca tcccaatttt ctggttctga aaaaccagct
     2581 tctgataatt tttctttgtc ataccaaata ccttgaaccc agccgctaat tggtgcagca
     2641 atatagcttt ttccatcttc tgaacgaaca aggtttttgg ctccgtcata ataattatct
     2701 tctccagctt cctcgataac gttttggact gccgtctgat caatcagttc atctttatcc
     2761 atcactttag caaaatcctg actgacttcc attacttctg gtaatttacc ggaacgagct
     2821 aacgtaacga tttttgtatt gaacgctgat tcttctaccg gcacttgctt gattttgatg
     2881 tctggatttt ctttttcaaa atcagcaacc agttcattga tcacacttaa tcgttcctgt
     2941 tcgacagaag agtgcatgaa ttgaatcgtt gtctgttgtg attcgttaga gctttgactt
     3001 tcaccacaag cagtaagaag aaatccagta gctagcagac aggtagtaac aataattttt
     3061 ttcatttttt tccacctctt attttattat tttcagccac atatattcat acggctggaa
     3121 tatcaacttt cgttcttgac tgcaatggat aatttgtcca gaaaacaggt ctaggtaatc
     3181 tccttttggt aaaagataac ctgctgattg attggaaaaa ttatggataa ctaagacttt
     3241 ctcttccttc gcttcgcgaa taaaactgat aaaagaatct gctgagtcca gtaagtaaat
     3301 caaactattc ggatggaagg ctttttcttt ttttcgaata gatagcatct gggtcaattc
     3361 accatatact gctgttctta atggatctgt ctgcaactct ttctcaatat ctgctaacaa
     3421 aaatttttgc cgattgattt ttcgattctc tcctgttttt tctacgcctt tgtaatcatt
     3481 tcgacttccc agcacacttt gaatataaat tgccggcacg cctggtaacg ttaccaaaaa
     3541 tgaatgagca gctaaaaagc gtttgcttct ccattccgtc gtatctgttg gagaacttaa
     3601 cgcatctaga tacgtagcgt ttatctcata tggactggtc gttccatctg ggtttttctt
     3661 gtagtttact cgggcaccct ctttcttcag ctgttccact aattcaagga tcgttttttc
     3721 cggcagaata cctcgtaccg gattcaatcc gataccgtca tgggaggcta aaaaattaaa
     3781 aaaagttgtt tttttcgatg cgaaatcgat ggtttttaac cattctttca acttacttgt
     3841 attacccgaa cgaatcgctt gaagggtcaa aggtggtagc gaaaactgat agaccatctg
     3901 tgcttcattc tcgccattcc caaaataact gatattatct ttgtgtggca catttgtctc
     3961 agtgatcaat accgttcctg gagctgcttc atcagcgatt gcacggaata attggatgat
     4021 tttatgcgtt tctggcaggt gtatacaaga agttcctagt tctttccata aaaatcccac
     4081 agcgtccaag cgaataaatg aagcgccttt ttctaagtaa aacaaaagaa tatcgatcat
     4141 tttcaataaa acttctggat ttttaaaatt caagtctact tgatcttcgc taaaagtcgt
     4201 ccatacgtgt ttttctttcc cgtttttgtc aatgaacgtt gtaagtaacg ggctggtcct
     4261 tggtctagtc acgctgcttg tatctgtatc cagtggcaaa tcaataaaaa aatctttgta
     4321 cgtatcattc aagtttaaat attcctgaaa ccaagtactt tcggcagaca tatgattgca
     4381 gacaaagtcg aacattaacc gtgtttcgct tctcatttct tctatatctt cccatgtgcc
     4441 caaacggtcg ttgattgcct gataatttac aacggagaaa ccatcatcag atgtatatgg
     4501 gaaaaatggc aagaaatgta caactctaaa tgtatctgcc aaatactttt gataaaattt
     4561 cttaaatgta cgcaaagttg gttgctgctc ttcaaaaaat tgatccccat aagtaatcaa
     4621 gaaaatatct tcttcgtccc aatgcagttt gcctgcctgg cctttcttct gctgataaac
     4681 actgactttt tgttcaatca tagaggcggt tttctcagac aaatctgagt cgcgataaat
     4741 cgcttgtaaa agttttgtat acatcggatt cccctttctt ttttgggagc gttcccaacg
     4801 atttgatcat attatggaaa acgcttactg tcaatagcat ttttttaaat aattttgata
     4861 tacacaaaaa tacaaataag aaagcttatg tatcaataat taatagcttc ttaaaaaaat
     4921 atggtctctc atgatcatgc aagctattcc taaattttca aaatcataga caaaaaagaa
     4981 tgtctattgt actatggaat tattctaaaa cgctcccaaa aaggaggtgc atataaaatt
     5041 gaaacctact atttatgaca ttgcgaaaaa agctaatgtc tcaaaatcaa ctgtctccag
     5101 agtattaaat aaccagccaa atatctctga taaagcaaaa gcaagtgtac ttcaagcaat
     5161 caaagaattg aattatgaac cgagcaaaat tgcaagagga ctgtcaggaa atggttttga
     5221 cgcgattcta gcattatctc atcgtacttc tcatacgacc tatggcaatc cttttttttc
     5281 agatgttatt caatccattt ctgccgtttc tgaacaaaat aacttcgact tgattctaca
     5341 aacggcaaaa acaccagaag aagagctaga aaaatgcgcg aaaaagatcc aagaaaaaat
     5401 gatccgagga attattattt taagctctac gatggatgaa acacttcttt ttgaattgga
     5461 tcaatacaat attcctattg tggtaatcgg aaaagtcgga aacgactaca cgaacatcta
     5521 ctcagtggac acggataatt tccaggatag ttacgatttg gtggaaacac tgatcaagaa
     5581 tggacaccgt catatcggct gtctccatgc tccgacagaa gtttatgtat ccaatgatcg
     5641 tctcaatggt taccgtcaat gcttatttga tcaccaccta gatatccgta atgaatggat
     5701 tatagacggc ggctttcgct tagaagatag catggcagca atgaatgatt taatgaagct
     5761 acgagaaaga ccaactgcga ttttttctac cgatgcatta aaatcattga gtatttacaa
     5821 agtggcagaa caatctggaa agcagatacc tgatgatctt tcgatcgcag gattcagtga
     5881 tcccttattg tcctccctat tttcgccaca gttgactcgg atagacattc cgacaaatca
     5941 gttaggaatc aaagccacag aacttttatt ccaactaatc caccaccaat accctgaaga
     6001 aaaaagaatc attctttcaa ccgagattac tctcacagat tcgatccaac aacaagaaat
     6061 gtagaacaga attataaaag aacagaaaca ctgaggataa gtcagttact ctgttctttt
     6121 ttcaatcact catccctcgt taccccctcc cggtatttta gcgaattttt cttattttcc
     6181 atctgtttta gatagctgtg gataactata atgtttgtgt taaactattt tttccacagg
     6241 gaagaaaaaa ctatttttaa ccacgttgtg tataagtttt tatagttcgt ttttttaaac
     6301 acatttaccc ttatttcaat ccatgttatt tggggatact tatctctaaa acataaatag
     6361 aataacagac atgtctactg gttttgtttt attcgaggaa ttattcaata atagctagca
     6421 aaatattaaa aataaccgct ctatcttccc atcaatttat tttgcattca aaaaatgatc
     6481 tatctttact tttgttgatt gacttctctt ggaagatgat cgttccgata ccttaattgg
     6541 atacgaaccg atgttgttaa gatcctttcc cacttttctt ctagttagac aaattatttt
     6601 agacaaacca aaaaagaggt tgtgacaata atttgtcaca acctcttttt taaaatatct
     6661 attttgtttg attgttcatt gcgtcttctg cagccatttg cgcttcaata tctgaaatac
     6721 tgtagacatt ttcgcttgct acaccgactt cttttggttc catgtcacga taacgttgca
     6781 taccagtacc agctgggatg atcttaccta taataacatt ttctttcaaa ccaagaagag
     6841 gatctttctt accgcggatc gcagcatccg tcaagacacg agttgtttct tggaatgatg
     6901 cagcagataa gaaactattt gtttctaatg atgcttttgt gatacctagt aagacaggtc
     6961 gagaagttgc aggaacgcct cctgagacta gcgtattgta gttttgatct ttaaagtctg
     7021 cgatgtctaa taatgtacct ggtaagatat ctgtatcacc tggatccatt acacgaactt
     7081 tacgcagcat ttgacgaacc attacttcga tatgcttgtc gccgatttct accccttgca
     7141 tacggtaaac acgttgtact tcacgaagca agtagttttc aacagataat acatcgcgaa
     7201 cttgcaacaa ttgttttgga tcgattgatc cttctgtcaa tggtgcacca cggtggatca
     7261 tatcgccttc tgctactttc atacgtgctg tataaggaac agtatacgta cgtgtatctg
     7321 tttttccttt gattgttact tctttggtac gtgttgcagg atcttctgag atatcgatga
     7381 catcccctgt tacttctgtg atcactgctt gccctttcgg attacgtgct tcaaagattt
     7441 cttggacacg aggaagacct tgagtgatat cgtctccggc aaccccacct gtatggaatg
     7501 tacgcatcgt caactgagta ccaggttcac cgattgattg agcggcgatc gtaccaactg
     7561 cttctccgac ttcaacgtca gagccagttg caaggttgcg tccgtaacaa tgtttgcaga
     7621 caccatgttt tgtattacat gtgaagacag aacggattgt cactgtttcg acacctgcat
     7681 caacgatttg ttttgcgatg tcttcggaaa tcaattggtt tcctgcaatg atcaattcat
     7741 ttgtttcagg atgacgtact tctttacggg tgtaacgtcc cactaaacga tcttctaatg
     7801 attcgatgat ttcatttccc tcgcggatgg cttggatttc aagacctcgg tcagtaccgc
     7861 aatcttcttc acggatgatt acatcttggg ccacgtcaac cagacgacga gtcaagtaac
     7921 ctgaatcggc agtcttcaag gctgtatcgg tcatcccttt acgagccccg tgagttgaga
     7981 taaacatttc caagacggat agtccttcac ggaagttcga aatgattggc aattccatga
     8041 ttcgaccatt aggagcggcc atcaaaccac gcattccggc aagctgtgta aagttggaaa
     8101 tgttaccacg agctccagaa tcagacatca tgaagattgg atttttcgct tccaaacctt
     8161 ccatcagttt ttgttggatg ctgtcttttg cagcattcca aacagcaatg acacgttcat
     8221 aacgttcgtc atctgtgatc agaccacgac ggaattgttt tgtaatagtt tcaacttgtt
     8281 tatgggcatt ttcaatgatt tcttgttttt cattcagtac actgatgtca gcgatcccta
     8341 ctgtgatacc ggcatgtgtc gaatgtttgt accctaagtc tttcatacgg tcaagcatct
     8401 tagaagtttc tgttactttg aatcgtttga agacttctgc gatgatgttt cctaagtttt
     8461 tcttcttgaa cggtaatact aattcttgct ctttgatatg tgcaggaata tcagtaccag
     8521 cttcaacaaa gtatttgtcc ggtgtttgga cggtcaagtt gaagtctgtt ggttcattca
     8581 gataagggaa ttcaggaggc atgatctcgt tgaagatgat cttaccaact gttgtgatca
     8641 tcgtacgttc tttttgccat tcagtaaatg gtttttcacc taatgagtta gggttcacac
     8701 cgatacgtga atgtaaatga acatatccgt tgcgccatgc gataacggct tcgttttgat
     8761 ctctgaagac cattccttcg ccttcgcgtc cttcttcttc cattgtcaag tagtagttac
     8821 ctagaaccat atcttgagaa ggagtaacaa ctggtttacc atctttaggg ttcaagatgt
     8881 tttgagcagc taacatcaac atacgtgctt ctgcttgtgc ttcttcattc aatggaacgt
     8941 ggacagccat ttggtctcca tcgaaatcgg cattataagc ttcacataca agtggatgca
     9001 aacggattgc gcgtccttgt actaaaactg gttcgaatgc ttggatacca agtcggtgaa
     9061 gcgtaggtgc ccggttcagc aatactgggt gttccttgat tacgtcttct aaaacatccc
     9121 atacttcgtc ttcttgacgt tcgattttac gtttcgcatt tttgatgttt gaagctagtt
     9181 cgcgttgaac aagctcacgc atcacgaatg gtttgaataa ttcaatggcc atttcttttg
     9241 gaagtccaca ttggtacatc ttcaagaaag gtccaacaac gataacggaa cgacctgagt
     9301 agtcgacacg tttacctagc aagttttgac ggaaacgacc ttgtttccct ttcaacatat
     9361 gagaaagaga tttcaatggg cggttacctg gtccagtaac tggacgtccg cgacgaccgt
     9421 tatcgatcaa tgcatctact gcttcttgca gcatacgttt ttcattttga acgatgattc
     9481 caggtgcatt caagtctaac aaacgtttca aacggttatt acggttgatt acacgacggt
     9541 aaagatcatt caagtcactt gttgcaaaac gtccaccttc taattgaacc attgggcgta
     9601 aatctggtgg aataacaggg ataacgtcca taaccatcca gcttggttga tttcctgaag
     9661 cgcggaatgc ttctaaaata tccaaacggc ggattgcacg tgtacgtttt tgtccttgtg
     9721 cagatttcaa ttcttctttc aattcggctg cttctgcatc tagatcaaca ttatcaagta
     9781 attgtttaat cgcttctgca cccatagcag cttggaattc ttgtccatat tgttcacgtt
     9841 tttcgcgata ttcgcgttct gtcaacaatt gttttttctc taaattcgta tttcctggtt
     9901 cgatgactac atatgaagca aaataaatga tttcttccaa agcgcgtggg ctcatgtcta
     9961 atacaagacc catacgtgaa ggaatccctt taaagtacca gatatgtgaa acaggagctg
    10021 ctaattcaat atgtcccatg cgttcacggc gaactttcga acgagtaact tccactccgc
    10081 atcgatcaca aacgattcct ttataacgga tacgtttgta ttttccgcag gcacattccc
    10141 agtcttttgt aggaccaaaa atccgctcac agaacaaccc ttcgcgttca ggttttaagg
    10201 tacgatagtt aatcgtctca ggttttttta cttcaccgta agaccagctt ctgatttttt
    10261 cgggagaagc caaacctatt tgcatacttt cgaatttatt tacatcgatc aaaaggggtt
    10321 ccctccattt catttaatgg caaaccgcaa gacggctgat cttcgaccgc cttgcagctc
    10381 atagaccgga ttagtctaaa ttatcttctg cggtttcaaa gttttggatg acatcgtctt
    10441 tttcatcttc cacttgttca gcagctttct tttctaattc tttggcagtt tgctgttcgg
    10501 caaattttgt caaagcatca acagtgatca aatcgtcgtc ttcatcgtcc atgtcgcgaa
    10561 gttcgatctc tgtttcttcg atatccaaga cacgcatgtc cagacctagt gattgcaatt
    10621 ctttcaccaa tacgcggaat gattccggta cacctggttt tggaattggt tcacccttga
    10681 cgattgcttc gtatgttttc acacgtccga ctacgtcatc tgatttgtat gtcaagattt
    10741 cttgtaaagt ataagccgca ccgtaagctt ccagtgccca tacttccatt tcaccaaaac
    10801 gttgtccacc aaattgagct ttacctccca atggttgttg tgtaaccaat gagtaaggtc
    10861 cgattgaacg tgcatgcaat ttgtcatcga ccatgtgagc aagtttgatc atgtacatca
    10921 caccgacaga cacacgtcca tcaaatggtt cacctgtacg tccgtcgtac agaacagttt
    10981 tcgcatcgct ggccataccg gcttcacgaa ctgtttccca tacgtcttca tcacttgcac
    11041 catcaaatac tggcgttgct acgtggatac ctaactgacg tgcagccata cccaagtgta
    11101 attccaatac ttgcccgatg ttcatacgtg aaggcacccc taaaggattc agcatgatat
    11161 cgattggtgt tccatcaggt aggaatggca tatcttcttc cggcataata cgggatacaa
    11221 cccctttatt tccgtgacga ccggccattt tatccccttc atggatttta cgtttttgaa
    11281 cgatataaac acgaactaac atgtttacgc ctggtgacaa ttcatctcca gcttcacgag
    11341 taaagatttt cacatcgtga acgataccgc cgccgccatg tggtacacgt aatgatgtat
    11401 cgcggacttc acgagctttt tcgccaaaga tcgcatgcaa tagacgttct tctgcagata
    11461 attctgttac cccttttggc gtgactttcc ctacaagcaa atcgccatct tggacttctg
    11521 caccaatacg gatgataccc atttcgtcta aatcttttaa tgcgtcttcc ccgacattag
    11581 ggatttcgcg tgtgatttct tcaggtccta attttgtatc gcgggcttct gattcatatt
    11641 cttcaatatg gatagaagtg tatacgtcat cttttaccaa acgacggctc atgatgatcg
    11701 catcttcata gttgtaccct tcccaagtca tgaaaccaac taaaacgttt tggcctagag
    11761 ccatttcgcc ttgttccata gatggtccgt ctgccagagt atcccctttt tcgactttct
    11821 cacccaaatg aacgattgga cgttggttgt agcttgttcc ggagtttgaa cgacggaatt
    11881 ttgttacatc gtatttatct aatgcaccgt tgtcgcggcg tacgcggatt tcagaagcat
    11941 caacgtattc aacgacaccg tcatgtttac ataacaaagc agctcctgag tcatgcgctg
    12001 atttgtattc cataccagta ccaacccatg gtgcttgagg attgatcaac ggcactgctt
    12061 gacgctgcat gttggcaccc atcaaggcac ggttggagtc atcgttttcc aagaaaggaa
    12121 tacatgctgt cgcaacggca actacttgtt taggtgatac gtccatgtag tctactttat
    12181 caatagatac ttctaagttt tcactttgag cacgagccat aacaacgtct tgagcaaatg
    12241 ttccatcttc attcaatggg ctgtttgctt gggctacgat gtaatggtct tcgatatcag
    12301 ctgtcaagta gtcgatttgg tcagtaacac gacctgtttc acggtctaca cgacgataag
    12361 gtgtttcgat aaatccgaat ttatttactt tcgcataact ggacaaacta ttgatcaacc
    12421 cgatgtttgg gccttcagga gtttcgatcg gacacatacg gccatagtgg gagtagtgaa
    12481 cgtcacgaac ttcataaccg gcgcggtcac gagtcaatcc gccaggtcct aaggctgaaa
    12541 gacgacgttt gtgtgtcaat tcgccaagag ggtttgtttg atccatgaac tgtgacaact
    12601 gagaagaacc aaagaattct ttgatacttg ccacaactgg acggatattg atcaattgtt
    12661 gaggtgtcaa tgtttcagta tcttggatcg acattctttc acgaaccaca cgttccatac
    12721 gtgctagccc gatacggaat tggttttgta aaagttcacc gactgaacgg atacgacgat
    12781 ttcctaagtg gtcgatatca tcgacattgc cgataccttc catcaagttc aagaaatagc
    12841 tcattgaagc aatgatgtcg gctggacgaa ccgtttttac agctgcttct ggatagccgt
    12901 ttccgatcac gtttacttca cgttcagggt ctcttggtga aaatactttg atgacttgga
    12961 cagtcattgg atctgtgacc acaccgtctt ctgatggata gtaagtcact gaatttaggc
    13021 cattatcaat gaaaggagct agtgtttcca tgacttggtg agtcagaact gttccttttt
    13081 caacgatgat ctcgcctgtt tctggatcaa ctaatgtttc agctaatgtc agattcaata
    13141 gacgtgtttt caaatctaat tttttgttta ctttgtaacg accaacgttt gctaagtcgt
    13201 aacgttttgg atcgaagaaa cgagcattca gcaagttacg tgagctgtct gctgtttttg
    13261 gttcgcctgg acgcaaacgt tcgtaaacgt ctttcaaacc ttcttctgtt cttgagtcgc
    13321 ttgcgttttt atgcaagtct ttttcgactg tattgcgtaa tgtttcgctg tcgccgaaga
    13381 tttcaaagat cgtatcatcg gaaccaaatc ctaacgcacg aactaatacg gttaaaggaa
    13441 tcttacgtgt acggtcgata cgtacataag agatgtcttt tgcatcagtt tccatttcta
    13501 gccaagctcc acggttaggg ataacagtag aaccgaatcc ttcttttccg tttttgtcga
    13561 cttttccatg gaaatagaca cctggtgaac ggactaactg agaaacgatt actcgctctg
    13621 ccccgttgat gatgaatgtt ccttgttctg tcattaatgg gaaatcaccg aagaatactt
    13681 cttgtgcttt gatttcgcca gtctcgcggt ttgtcaaacg caatgttaca tgtaatggtg
    13741 cagagtagtt tgcatcatgc gcacgagctt ctgctactgt atactttggt tctttcaatt
    13801 cataatctac aaattccaaa gatagattgc cattgaagtc atcgattggc aaaatgtctt
    13861 caaacatttc tctaagtccc tcatctaaga accattggta agagtctgtt tgaatttcga
    13921 tcaaatttgg taattccaac acttcactga ttcttgcgaa acttctacgt tcgcgatgtt
    13981 ttccgtattt tactacgtgt ccagccaagc tcttcacccc tctaaaatgt cattcaaaaa
    14041 gactacccga tcaattgtta caataatatt tcaaatatta tttttaggta acaacagaca
    14101 ttttttgcgg cttttaggca aaaaaaaacc aaaaatagaa cattctcttg aaaccttact
    14161 tcgtgagctt ctacttttgt ttccttatat taaagccgaa acggacaata tttcgtttct
    14221 gccttttctt catcagatag tttttgcaac ttcatatact acacttattt tctataaaag
    14281 tcaacacttc ctggcgtttc ttctgctttt tcgcaacatt ttcttaatgt tttcaatttt
    14341 atgttttcaa ttatctgaca attcttaatt gacagacctt tttatctcgg ttatacttta
    14401 gaaaattcat tttgtggagg aacttctatg cgaaccaaca tcaaccaaat cgcaccaaca
    14461 caactgaata acttttactt tagctacttt agataggttt gtattcatca tgatggatac
    14521 aaacgttaaa cgacagtttg tatctatgat ggctaaagaa ctttgtattg cagcaaaaag
    14581 ccacgtagac aaaatgctaa gtggctgagc agtgaaaata caaagtaaaa gtatcaagca
    14641 ttctactttt tcaatttatt ttccgacttt tcaatccatt tggacatttt gtctgaatgg
    14701 attttttgtt tcccaaaatt aaggaggaaa aagaaatgaa aaaaaatata atcatcggat
    14761 taggcgctgc cctgctacta gctttaggag gttgcgcaca aaaagacaat tccgcagagg
    14821 catcagatgg acaaaaaaca attggcgtat tgcaacttgt acaacataac tcgttagatg
    14881 ctgcctataa aggattcaaa gaaggattag cagaagaagg gtataaagaa ggcgataatc
    14941 taacaatcga ttatcaaaat gcccaaaaca atcaagacaa cctgaaaagt atgagtgaga
    15001 aactcgtcaa agaagatcct gatttgctac ttggaatcgc cactccagca gcacaatctt
    15061 tattaaatga aacaaccact atcccgatga ctgtcacagc ggtcacagac ttggaacaag
    15121 cccatttagt cacatccaat gaaaaacctg gcggcaatgt gactggcacg acagatatgg
    15181 tgccaatcga aaaacaaatc ggcttactgt taaatatcgt gccagacgcc aaaacaatcg
    15241 gcatcatgta taacaacggt gaagcaaact ctaagatcca agctgatttg gcagaaaaag
    15301 aattgaaaaa agcgggcgtc aaagtcaaag tactgacagc aaattccaca aatgatgtcc
    15361 aacaagtgac gaaaagtcta gctaaagatg tagatggaat ctatattcct actgataaca
    15421 cgttcgcaag tgcggcaagt gttgtcggtg aagtcgcaaa agaaacaaaa acacctgtcg
    15481 ttgctggcgc agttgatcaa gtcaaagacg gcggtctagc aacagtagga atcgactacg
    15541 aaagcttggg caaacaaaca gggatcatgg cagcaaaaat cttagacggc aagaatccaa
    15601 gtgaacttcc tgtcgaaaca gcgaatgatt tggaactgta tgtcaataaa gacatggcca
    15661 aagcattagg catcaatcca gacagcatca aagaagctga ataaaacaca ggaggattct
    15721 catgacaaat ttgctctctc ttttcttatc atctgcatcg caaggggtct tatgggccct
    15781 acttgcgatt ggtgtatacg tcactttccg tatcttggac attgccgact tgactgctga
    15841 aggaagcttt cctttaggtg cagggatcgc ggcagtaagt attacaaatg gctatcatcc
    15901 attgacagct tgtcttctag gctttttagg gggtgcggca gcagggcttg tttccggact
    15961 gcttcacaca aaattgaaaa ttcccgccct tcttgcaggg atcatcacca tgactggttt
    16021 atattctgtc acatcccgtg tgatgggtgc gccgaacatc tctttattgg gtcagccaac
    16081 gatctttcat tgggtcgagt cattcggcat aacaaaagac aacgctgtac tgatcgtcgg
    16141 tctgcttttt gctttgatcg ttgtatgttt acttgttttg ttcttacgta cagaaacagg
    16201 acttgctatt cgtgcaactg gcgataatct ggcaatgagc gaagcaaacg ggatcaacac
    16261 agataatatg aagatcatcg gttatatgat ttctaatgga tgcattgctc tttctggctc
    16321 cttacttgcg caaaacaacg gctttgctga tttaaattct ggtattggaa cgatcgtaat
    16381 tggacttgct tctattatca tcgcagaagt tttgttacgt aaccagccac tatttctccg
    16441 tctcttgact gtcgttttag gtgcggtcat ttatcgtttt attttagcgt tagtcttcga
    16501 actgaatgtt gaaccaagtg attcgaaact tgcttctgct ttcgtgctag tgatctgtct
    16561 ttctttcccg cagatccagc aaaaattcca tttacctcaa aaaaagaaag gcggtagtgt
    16621 caaatgaatg acgtcttaac attggaaaat ctccatcata cctttgaaaa aggaacgatc
    16681 aacgaaaatc atgtcctgaa aggcattaat ctttccttag atcccggcga cttcgtgacg
    16741 atcatcggtg gaaatggggc tggtaaatct actttgctga acagcatcgc cggtacattt
    16801 tctgtcgatc agggtcaaat tttattgaat ggaaaaaata tcacgaaaaa atctgttgtc
    16861 gaacgttcga aatccatcag tcgcgtattc caagatccta aactagggac agccgttcgt
    16921 ttaacggtag aagaaaatct tgctcttgct atgaaacgag gaaaaaaacg cggcttcttc
    16981 cgtggtgtca aaccacaaga ccgaacattt ttcaaagacc agctggttcg gctaaatttg
    17041 gggttggaaa atcgtttatc ctcagaaatc ggtttgctgt ctggaggaca acgtcaagct
    17101 attacgttat tgatggccac attacagcgt ccagaactga tcttattaga tgaacacact
    17161 gcagcgcttg accctgctac ttccaaaacg gtgatggaat tgacagaaaa gctgatcact
    17221 gagcagaatc tcactgcttt tatggtcact catgacatgg aagacgcgat ccgctatggg
    17281 agtcgactga tcatgctgca tcaaggaagg atcgtcgtag atatccagca agaggaaaaa
    17341 cagcagctca cagtgcccca attattagcg ttgttcaaac aaaacagcgg cacggcatta
    17401 aaagacgatc aagtactttt atcttcataa tcagaaagag gatgggacaa aaaatgaacg
    17461 cccaccctct tcttttttct ctttccttct ttcgtttttg ctttatgtat caaccgttgt
    17521 ttcttcgaaa actattttgt tctctccttc ttcctgatag aatggatggg aaaggagctt
    17581 gatgccatga caacgaaaga caaggtactt caattattga aaaagacacc agattttctt
    17641 tccggagaaa agttggcaca gcaactggaa gtttcccgga caagtatttg gaaagccatc
    17701 aaagaattgg aaaaggcagg ctatcgtttt gagcacgggc ctacagggta tcgttacctg
    17761 ccctctgacg tactagatgc aaaagaaatc cagcaagagc tacggtcgtt tattcctgat
    17821 ttgaaagtac aaacgatgtt gacttctgaa tctacgatga aagatgccaa actggcagca
    17881 gctcaaggag attctgtttc gaagttattt gttgctgata cacaagaaca agctcgtgga
    17941 cgttttggac ggcctttttt cgctgaacct ggacgaggaa tctacatgag tctcttgctc
    18001 catccagaca aacggtttga tgaattgcct caatatacga tcatcgcagc cagtgcctgt
    18061 gtgaaagcca ttgaatctgt aaccggtcgt tctgcttcga tcaaatgggt caatgatatc
    18121 tacatggatg gaaaaaaagt ctgtgggatt ttatctgaag cagtcagtga tatggaaagc
    18181 ggcaggatca gtcatatcat cattgggatc gggcttaatt tttctgttcc tcaaaatcat
    18241 tttccagctg atctccaaga aaaagccatc tctgtctttc ccgacggaca agctagtgtc
    18301 acaaggaatc agctaatcag caaaatctgg caagaattgt tcacttatct ttctcaccca
    18361 gaaaaagcgt tggacttcta taaagaaaaa tcattcgtat tgggaaaaac cgtgtcgttc
    18421 aatcaaaaag gaacgactta tgtcggtctt gcaaaagaaa tcggtgatca tggcgaactg
    18481 atcgtccaaa caaatgaaca gaagatgagt ttgtcttctg gcgaaatcag tctcacatct
    18541 atccgtacgc aataattatc agatttcaca aaaggacacc tgatctcata cagtgtcctt
    18601 ttttctgaat tctcttcaaa agactctcct tattctatca gctgacagtt tctctatcct
    18661 ctagaaaaag gtattctaaa aatatctata aagcatggta cactttcttt aaatgaatca
    18721 atgcaaaaaa caagagagtc atcagtttac acgatcaaaa gagatagcag gccgcttcct
    18781 ttttcaatct tatagataga ccatgggtaa cgataaaaac aaaaaagaac ttgcgactta
    18841 ttttgccgta agttcttttt tagctagtgc cttaatctct taatcccaac aaacgtctcg
    18901 catagatcac ctgaccagag tgcatagcag catcatcaat aatagaaacg agacgcattc
    18961 ctcgtgtgac tggtggtgtc cagttctcgt caattacttc atctagctcg gaaggttcca
    19021 gccttcttaa gtaagaaata gcaaaatcag cagctcctcg caagtatcct agcagatctt
    19081 ctatttgatt agcttggatc tgctttgctt gttccagact atgcttccaa tcttgttcgt
    19141 tatctgctat cgtcatcgga aaccggcttt cccagtcttg actatgccaa attggagaag
    19201 ttcctgctaa atcagcaatc tggaaatcta attctcgagc ggtatgccaa gccagccaag
    19261 tcattgattt gatctgcggg gctctatctt ccactggaaa acgattggcc tcctcaatag
    19321 agacgccttc aaacaaacgt tcaaaccgat cgtatgcccg atccacactc tcgcatagca
    19381 tatctaaata atccatttat tttcctcctt tttatttatc ctacttactt tttcctaatt
    19441 ctaggatacc tacttatatg ttactacaca cccttatttt ttacacttta acagtcacca
    19501 tcatcaatag tttggagatt gaaagaaaaa gatagtgtcg aactatcaat tgaacaagaa
    19561 gcaacaatat gaacgtttca ttaatattct ttaaataaac aatgattttt caaacgaaca
    19621 gtttaagact aggagaaaaa gagtataata ggaaaatgtt tgaaaggaaa ggaaggggaa
    19681 aaatgaaaaa aagggcaagt ttactagtcc tagttgcttt gttgttcaat atcttttcgt
    19741 atggtgtggc cgtttcagcg gaaacataca ttcctaaaga ccctgggaat atttataatg
    19801 atctaactgg taactatggc ttgttaggaa ttgctagtca attccacgta tttgctaaaa
    19861 ataagacaac tgtgaatgca catacagacg gaaatatagc aacacatgaa cttgatgcaa
    19921 aaaataattt tggtacagag cttcatgaag gtttattgaa ccaagaaata aattatatac
    19981 aaaaaactga ttctttcgct aattcttcag gcatacctac aggtagcaca agaatgaata
    20041 aatttgtcgt tggcagtaac gtggatgtag cacttcaaga tggtcatcct acagtcaatg
    20101 gatccaggct tgatcactta actccagatg atttttataa agatcgtgct gggcatgaat
    20161 atattgattt cgagcaggaa tttgctaaat tgaatgtagc agcaaatgat cttgcaacga
    20221 tcactccagc taaaacatat actgctgcag attttccaga catgaacaat cggacaatcg
    20281 atttaactga tttatcagat accgggtttt tattggtaaa tatcgatgca gaagtgttaa
    20341 cgatgaatac gccacttcaa atcattaatc caaatgatca agtagttgta tttaatgtca
    20401 tcaacagttc ttctgcattg aacgtacagt caccaatcaa atacaatgat cgttcaaatc
    20461 atgaaacaga agatttttcg gatgcgaata tctcttggaa ttttggaaat gagatgactg
    20521 atttgacaat cagtgctcct tttcaaggaa caatccttgc gcctaatgct actatccgca
    20581 ttactcaaaa ccaagacgga acgattatag gaacaaatgt gattttagat gcagctacca
    20641 atcgttggga tcctaacgaa atatttatca gcgacaatgg tacagatacg acagacacaa
    20701 gcgacagtac agatacatct accacaagtg atagctcaga ttcatcaact tcaagcgaca
    20761 gtacagatac tacctctacc acaagtgata gcacggatac atcagcttca agcgacagta
    20821 cagatactac ctctaccaca agtgatagca cgg
//
LOCUS       DAJSMK010000042        20411 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.044, whole genome shotgun sequence.
ACCESSION   DAJSMK010000042 DAJSMK010000000
VERSION     DAJSMK010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.044"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..2120
                     /gene="acm"
                     /locus_tag="ON488_001557"
     CDS             <1..2120
                     /gene="acm"
                     /locus_tag="ON488_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HCR3231755.1"
                     /translation="NITSLIPVHVYADAGRDISSNVTSLTVDPTNITDGGNIKVKFSF
                     DEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGTLTVRKDSAQVVFNEN
                     IKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVNVTKPASGSSSSVFYY
                     KTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLDPSTFEINQIHLGEQK
                     VYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKIMVSYKTIIENPEQIN
                     FENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGELKIFKYINDTEIGIPN
                     VTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKEKEAPNWIDFDPLSSN
                     ELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSIYFKLFRASTNNWEPV
                     PDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGNDYVPSGYQKIENGLVV
                     TNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQHKEVSEKDDWRYRFTN
                     LPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNISIPGSHITPWKNFPEK
                     TEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNKSKSILPKTSSKKSSF
                     AVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2392..2877)
                     /locus_tag="ON488_001558"
     CDS             complement(2392..2877)
                     /locus_tag="ON488_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HCR3231756.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    2967..3312
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3357..3998
                     /locus_tag="ON488_001559"
     CDS             3357..3998
                     /locus_tag="ON488_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HCR3231757.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4017..4652
                     /locus_tag="ON488_001560"
     CDS             4017..4652
                     /locus_tag="ON488_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HCR3231758.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4670..5485
                     /locus_tag="ON488_001561"
     CDS             4670..5485
                     /locus_tag="ON488_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3231759.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5804..7240
                     /locus_tag="ON488_001562"
     CDS             5804..7240
                     /locus_tag="ON488_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCR3231760.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7429..9876
                     /locus_tag="ON488_001563"
     CDS             7429..9876
                     /locus_tag="ON488_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCR3231761.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10106..11173
                     /gene="rlmN"
                     /locus_tag="ON488_001564"
     CDS             10106..11173
                     /gene="rlmN"
                     /locus_tag="ON488_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HCR3231762.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11366..12469)
                     /locus_tag="ON488_001565"
     CDS             complement(11366..12469)
                     /locus_tag="ON488_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HCR3231763.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            12862..14112
                     /locus_tag="ON488_001566"
     CDS             12862..14112
                     /locus_tag="ON488_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCR3231764.1"
                     /translation="MKLFIGLDVSSQKLDTCFLTDSKEILFEGSLSNDLIGASEIKQR
                     ILEYQETFGFYQIVIGMESTSVYSFHPAMFFYLDEDLKLLPVEVTVENPYRIKQYSRM
                     FDQDKTDKIDAQIIADYLRVDLHTLSPIKEEVYVGLQRLTRSRYQLVTQMVEAKQHFL
                     ENLTYKCNTLSKELANEDNKTSIFGASIMNLLTEGITLDEFSEMPLEAAVELLQKLGK
                     GRFKNPEQLVKSIQKAVRSSYRLGKVTKNSIDLVLGIIANEIKFLKKQIKEIEKAITA
                     LLETIPEAQCLLSVPGLGAVYTAGLIAEIGQIERFDDQSKLAKYAGLTWTKNQSGNSQ
                     SENTPLNRSGNRYFRYYLIEATNRVRSTLPEFKEYYQKKRNEVPKHKHKRALVLTGRK
                     FVRLIDALLRNGQFYQPAKVVIEK"
     gene            complement(14251..14784)
                     /locus_tag="ON488_001567"
     CDS             complement(14251..14784)
                     /locus_tag="ON488_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCR3231765.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(14805..15749)
                     /locus_tag="ON488_001568"
     CDS             complement(14805..15749)
                     /locus_tag="ON488_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HCR3231766.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            16386..16472
                     /locus_tag="ON488_001569"
     CDS             16386..16472
                     /locus_tag="ON488_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCR3231767.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(16593..17282)
                     /locus_tag="ON488_001570"
     CDS             complement(16593..17282)
                     /locus_tag="ON488_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231768.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(17289..17567)
                     /locus_tag="ON488_001571"
     CDS             complement(17289..17567)
                     /locus_tag="ON488_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231769.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(17527..18441)
                     /locus_tag="ON488_001572"
     CDS             complement(17527..18441)
                     /locus_tag="ON488_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCR3231770.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(18423..18803)
                     /locus_tag="ON488_001573"
     CDS             complement(18423..18803)
                     /locus_tag="ON488_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCR3231771.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(19253..19540)
                     /locus_tag="ON488_001574"
     CDS             complement(19253..19540)
                     /locus_tag="ON488_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HCR3231772.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(19560..19784)
                     /locus_tag="ON488_001575"
     CDS             complement(19560..19784)
                     /locus_tag="ON488_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HCR3231773.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
BASE COUNT         6495 a         3582 c         4008 g         6326 t
ORIGIN      
        1 ctaatataac atcactgatt cctgttcatg tctatgcgga tgcaggcaga gatatcagca
       61 gtaatgtcac ttcgttgacc gtggacccaa cgaatattac agatggagga aacataaaag
      121 taaaattctc gtttgacgaa aaaaaacaaa atatccaacc aggtgattat ctttggatca
      181 attggccaag tgaaggaaat attcgcggtg aaggattcca aaaagaaatc ccattaatga
      241 ttgaaaataa aaatgttgga actttaacgg tcagaaaaga ttctgcgcag gttgtgttta
      301 atgaaaatat taaaaaccta gactcagtag aaggttgggg gcaatttgag atacaggcca
      361 gaaacgtaac cgataccggt gaagaaaata cgggaccatt caccgtgacg agcggtgata
      421 aaacagctac tgtaaatgtg acaaagccag cttctggttc ttcttctagc gttttttatt
      481 ataaaacagg agacatgcta cctgaagata ctaagcacat tcgatggttt ttgaatatta
      541 acaataacgg cacttatgtt gaacaaccag ttaaaatcag tgatgaaatc caaagtggac
      601 aaagattaga tccaagtacg tttgaaatta atcaaataca cttaggtgaa cagaaggttt
      661 atagaggaga agagggaatc caacaatttt tacaagattt ccccagcgct acatttaatt
      721 tttcagtaac tgataattac attgaaataa ctataccaaa aaactttgtc aatcttagga
      781 aaataatggt gagttataag acgatcatag aaaacccaga acaaataaat tttgagaatc
      841 attcggaagc ttggtttaaa gaatttaata aacctgctgt tgatggagaa agtttcaatc
      901 atacagttaa aaatatttca gcttctggtg gagtcaacgg tacagttaga ggcgaattga
      961 agattttcaa atatatcaat gacacagaga ttggtatccc aaatgtgact ttcgaattaa
     1021 gacgagcaga tgaacagcct attcaaggac agtctagtat cctgttgact tcgaatgaac
     1081 agggagaagc tagtatcaaa ggcctgcaag taggagacta tgttgtaaaa gaaaaagaag
     1141 cacccaattg gattgatttt gatccactaa gttcaaatga actcaaattc tccataaacg
     1201 aaaatgatac agagggagtc agtttaccta tttataacaa gaaaaaggtt acgaacatca
     1261 cagcaactaa aatttggaac ggtggaacca ctccaagacc gagtatttat tttaaattat
     1321 tcagagcaag tacaaacaat tgggaaccag ttcctgatgc agaaacaaaa cgattagaca
     1381 atggaataac ttcagtgact tgggaagata tccaacagta tgatgatagt ggaaacgaat
     1441 atacgtttaa agtgcaagaa gtagatcaaa acggaaatga ttatgtccct tcaggttatc
     1501 aaaaaattga aaacgggcta gtcgttacaa atgagaataa agaagtcatt tcagtctcag
     1561 gacaaaaaac atgggaagac aatgagaacc aagacggcaa acgaccgacg acgatcacag
     1621 taaatctatt agccgacggt caaccgatcc aacacaaaga agtaagtgaa aaagatgatt
     1681 ggcgctatcg tttcacaaat ctgccaaaat acagagacgg gcaagaaatc atctatactg
     1741 taacggaaga caacgtgccc gaatacagta cgacgattga cgggtataac atcaaaaaca
     1801 gttatacacc ggaaaaaaca aatatatcta taccaggtag ccatataaca ccgtggaaaa
     1861 attttccaga gaagacagag agagagaaaa ttagaaatct attctctcaa aaattgcaaa
     1921 tatttgctca tacaggagaa tccagcgaac aaagaagcaa ttatattagt aagagagctg
     1981 tacctaaaca gataacaaat aaatcaaaaa gcattcttcc taaaacaagt agtaaaaaat
     2041 ctagttttgc tgtaatcatt ggtttattga tagtaactat ctgtgctggg atattcttac
     2101 aaaaatataa aaaagtttag ttagaatata atattttttg ttaaatatga ctgaaatcaa
     2161 aagaataaaa ttccgattta taatcgaaaa aagaagcatt tttatatatg cttctttttt
     2221 cgtagaatca ataaatatgg atttggctaa ctatggaaga atactcgtat tagttttcag
     2281 cgttcatact agttgttaca ttgtttgatt ggccaaaaga atttctgata tattttgtgc
     2341 taaataaaga aaaagacgct tgaattggga aataagaaaa ctactctatc attacaaatt
     2401 ttcataaact ggcagatgtt ctaagtaaac aagtatcttt tcaaagtcgg aaaaatccat
     2461 aatcaacgta gtggtattga tatttggatg aaagcctacg gtatcttgac gatcaatagc
     2521 agcatcgatc acgacttgga tttttttctc tttgtcgtgc atcaatgcta atggagtcac
     2581 tgtacctgct ggaacgccta ggaggtcagg aagctgttct tcagaaacaa aagataagcg
     2641 cttttctttt aattgttcag ctagttgttt taaatcggcg tgcttttcat caggcaagat
     2701 gacaagatag atttgttttc cttttcttga tttcaataat agatttttta cttgcggacc
     2761 aggtagggaa aaagggacat ttttgactga cgtaatcgca ggatgatcga ctttttgaaa
     2821 agagataccc agttttttta gtagttcata agcttcttgt tcggttgcac gactcatcgc
     2881 gcatcaccct ccttttttta ttagtgtatc ataaaaaaga gttgacaaat gaaaaataat
     2941 catgtaaatt acacgtaaag ttaaaacaaa tgacatcgaa aagaagagta gccgttaggt
     3001 gtttttagag agtctctggt tggtggaaag aggcagcagt taaccgtgaa acacatcttg
     3061 gagtcgattt tctgaagcgt atagtaggaa aatccgggga gcccgttaca gctgcggtcg
     3121 ttgctagatg accagataag gctggctttt ccgtgaggag tcggtaaaaa aaggtggaac
     3181 cacgtgatta acgtcctttg atcttcggat caaaggactt tttgttttca tctgaacggc
     3241 aacgactgtg tgaggttttt tctgcaagga aaaaataaac agaggtggaa ccacgtataa
     3301 tacgtcctct tggcatttgc caagaggatt tttttatttt aaaggaggaa aagaagatgg
     3361 agtatttgat tgaagttatg ccgcaattat tagtaggagc actcacaaca ttgaaattat
     3421 ttttatttac cttgattggc tcattaccat tagggattgt tttagcatta ggattgtctt
     3481 tgcattttaa gccgctacgc tacttgcttc aaacatatgt atgggttatg cggggaacac
     3541 cgctgttgtt gcaactgatt tttatttttt atgggttgcc gacgattggg atcgtttttg
     3601 atcgtttcga agcagcactc attgccttta tcttaaacta tgcagcttat tttgcagaga
     3661 tctttcgtgg agggatacaa tcgattcctc aaggtcaata tgaagcagcg caagttttgc
     3721 aattaagtcc ctttcaaacg gtgacgaaaa tcgtcatccc acaagtgaca aagattgttt
     3781 taccttctgt agggaatgaa gttatcaact tggtcaaaga ttcttccttg atctatatat
     3841 taggtttagg tgacgtaatg cgtgctggga aaatcgcgat ggaacgcgac gcgactttac
     3901 tgcctttgct aggcgtggca atcatctatc ttacattgac tggtattcta acaatcgtaa
     3961 tgaaacaagt tgaaggaaaa ttaaattatt accgctaact gataggagga agaaatatga
     4021 ttgaattgaa gaaagtgaac aaagcatttg gtgaaaaaaa aataatcaaa gatttgaatc
     4081 taatcattcc agatgggaaa acattagcta tcgtaggtcc ttccggtggc ggtaaaacca
     4141 cgcttttacg tatcttggct ggcttagaaa gttctgacag cggagaattt tatttagacg
     4201 gtgtaccgtt caacccattc gagcttaaaa tgaaagaaca agttgtagga gtcgtattcc
     4261 aagacttcca gctatttcca catctgaata tttttgaaaa cattacctta gcaccaaaaa
     4321 tggtattgaa acagacaaaa gaagaataca ccaaaaaagc agaagaatta gcggcttcat
     4381 tagggattag tgatttattg aatatctatc cttatcagct ttctggcgga caaaaacagc
     4441 gggtagcgat tgccagagca ttggctatga atccacgggt attggcttat gatgaaccaa
     4501 caagtgcttt agatcctgaa ttacgccagc aagtcgagcg tttgatccta tcattgaaag
     4561 aagatggggt aacccaaatt attgtcaccc atgatttagt atttgcagaa aatgtcggtg
     4621 atcaattact aaaagtttcc ccaattcatt aagaaaggag aagatagaga tgaaaaaaac
     4681 cagttttcta ttcgctttga tcgcaggtct tcttcttttt gcaggctgtt cgaacaaaaa
     4741 aacttcagca gataattggg cgactatcaa cgaagagaaa aaaatcgtta taggtttaga
     4801 cgatacattt gttcctatgg gatttagaga taaagacggg aagctcacag gatttgatat
     4861 tgatttagcc aaagcagtct ttgaacaata tgggattacg gtagactttc agcccattga
     4921 ctggtcaatg aaggaatttg aactgaacaa tggaacgatc gatttgatat ggaacggcta
     4981 ttccaaaacg ccggcaagag aaaagaaagt gcaatttaca aaaccttata tggaaaacga
     5041 tcaagtgctg atcacaccta aagaatcagg aatcacaaac tttggacaaa tgaataataa
     5101 gagattaggt gcgcaaaatg ggtcatctgg ttatgatgta tttacgaaac aaccagaagt
     5161 attaaaagag atagtcaaaa accaagatgc tgttttgtat gatagtttta atgaagcatt
     5221 gatcgatctg aaaagcagac gggtcgatgg tctgctgatg gataaagtat acgcagacta
     5281 ttatttgaaa caaagaaacg aactagaaga cttcaacata acaaaaggtt cttatgagag
     5341 tgaggatttt gcagttggtg cacgcaagtc agatagtaca ttagtgaaaa aaatcaatga
     5401 agccctagat caactagaga aaacaggtga attccaaaaa atatccgata aatggtttgg
     5461 cgaagatgtt acgccgagaa attaacaaat aggggactgt gacaaaagac gtgtcacagt
     5521 ccctttttcc gaataaacag tgttctcctg ccaactcctt gtgactcgga gctgaatggc
     5581 aggctcacaa cctcttggta aacggtgttc aaaagccagt ttttcggtat taagccaaat
     5641 ttatgcaaaa atgtagaaag ccattttcac aaaatttttc ttactactcg aaactaagcg
     5701 actttttcac aacctccttt acatattttt attttgttgt ggaaggggtt tcgtgttatt
     5761 ctaaaagagg aacgattgaa ggttatagga aaggaagaga tgaatggaac acaaagaact
     5821 tacctcattt ccaaaagatt ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg
     5881 agcttggcaa gaagatggga aaggagaatc agtctgggat cgatttgtac ggatacctgg
     5941 aaagacattt aaaggaacga acggtgattt ggcagtagac cactatcatc gttataaaga
     6001 agatattgct ttaatgaaag aacaaggtct gaaagcttac cgcttctctg tagcttggac
     6061 acggattttt cctaatggac gaggagaagt caatcaagct gggctcgctt tttatgagag
     6121 attgatcgac gaattgattg aaaacgatat tgaacctatg ttgactttat atcattggga
     6181 tcttccacaa gcattgcaag atgaatataa tggttgggaa tcacgtcaga tcattgaaga
     6241 tttcactcat tatgcagaaa cattatttga ggcattccgc gggaaagtcc attactggat
     6301 tagtttgaat gaacaaaata tcttcacttc attaggttat ttgttagcag cacatccgcc
     6361 aggtgtgaca gacccgaaac gaatgtatga agttaaccat attgctaatt tagcaaatgc
     6421 atctgtcatc aataaatttc acgagttaga aatgcctgga aaaatcggac caagctttgc
     6481 gtatacgcca aattatccaa ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc
     6541 agaagacctg atggccaatt attggatgga tgtctatatg tggggaaaat atccgattgc
     6601 tgccatgagg ttcttagaag aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga
     6661 attgctagaa tctgctaaac cagattttct tgggatcaat tactatcaaa cggcgacgaa
     6721 tgcattcaat ccattaaacg gagttggtgc tggaaaaatg aatacgacag gaaaaaaagg
     6781 ttcatcagaa gaaactggag ttcctggaat gtataaaaaa gttgagaatc catttgtcga
     6841 acgaacaaat tgggactggg agattgaccc agaaggatta aggatcggac tgcgtcgtat
     6901 cacaagccgt taccgcatgc cggtactgat tacggaaaat ggcttaggag agtatgacaa
     6961 gttgacagaa gataaacaaa tccatgacga ctatcgaatc aattacttac aaagccacgt
     7021 caaagccatc aaagaagcaa tttcggatgg agcagaagtc ctaggctatt gcacctggtc
     7081 ttatacagat ttgcttagct ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt
     7141 tgatcaagac gaaacacaag aaggatcttt ggaacgatat aagaaagaca gttattactg
     7201 gtaccaaaaa ctgattgaag aaaatggaga gaacctttag ttcacatact taaaacaaga
     7261 aggtacggct ggatatggcc gtgccttttc ttgataaaat catttagaaa ttaagaaaaa
     7321 ctgtaaaata agctgaaaaa tgaaagaaag cgtcagttct ttcaaacaaa actttagttc
     7381 ccttactttt ttttgtataa tgaaacttga tgaaatgagg gataataaat ggcacaaaag
     7441 aaacggccta ctaaaaaaag gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag
     7501 gaacaaatgc tgacgattgg tgttgggttt gccttgattt tatttgctgt cttcggcttt
     7561 ttaaaattag gttttttagg aatattgatt gcaaacggct ttcggatcat tgcaggaaat
     7621 acttaccaaa tcctctgtct tttattagcc gtattaggat tttggattgt cattaagaat
     7681 acagagtttt caattggtaa aaaccgacgc tggtttggcg gcatactctt ttatttcggt
     7741 atcttattat tgttacatgc ccatttattt ggcaaactcc atactgggga accaaatatc
     7801 atggggacga catgggattt gttagccagt gatataaaac aaagtcaagt agacaataac
     7861 gttggtggtg ggatgattgg agcaatcctt tatcatttta cttacttctt gattgcacag
     7921 cctggaagtt atttagcagc agtgctatta ctggcaggag gagcattcct gttcagtaat
     7981 ctggaaggct atcagctgtt aaatggtatc caatcaattg gagaacgagt acaggaatta
     8041 ttggaaggtg atcctgccaa gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa
     8101 cagcgcgcag aagcgaaaga agcaaggcgc ttagctgcaa aagaagctgc agaaaaagaa
     8161 gctgcagaat atgagaagaa aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa
     8221 tggcaggaac cagaaaatac agagccggag cagctaagtt ttgttccaat cgacagtttt
     8281 caagaaaata tccatcctgc gaatctagag aaaccagtac cagatacacc aaaacagacc
     8341 aatacagcag aaggtttttc agatgagttg ccagaggatg acggtacctc attagaattt
     8401 gagattgaag cagaacagga aaatcaagac tatgaattac cgacagttga tttgcttgat
     8461 tctataccaa ctgtggatca aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta
     8521 ttagaacaaa ctttccaaag tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga
     8581 ccatccgtca caaaattcga agtccagccg gctgtagggg taaaagtaag taaaattgtg
     8641 aacttaacag atgatatcgc gcttgcttta gcggcgaaag atgtccggat ggaagcaccg
     8701 attccaggta aatcactgat tggtattgaa gtaccaaatg gaaagatcag tatggtttcc
     8761 tttagagaaa tcatcgaagc acaaccaaac cacccagata aattactaga agtaccttta
     8821 ggacgtgatg tttctggacg ggtacaaacg gctgatcttt cgaagatgcc tcacttactc
     8881 gtggctggtt cgactggtag tgggaagtca gtagcaatta atgggattat cacaagtata
     8941 ttaatgcgtg ctaagcccca tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa
     9001 ttgaatatgt acaacggcat acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa
     9061 gcagcgcaag ccttacaaaa agtagtacaa gaaatggaag aacgatatga aaaattcgcg
     9121 gcaaccggag taagaaatat ttctggttac aatgaatttg ttcaacagaa aaacttggaa
     9181 aacggaacga aacatccaac cttaccattc atcgtagtga tcgtagatga attagctgat
     9241 ttgatgatgg tagccagcaa tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct
     9301 cgggcagcgg ggattcatat gatcctagct actcaacgtc caagtgtgga tgttatcaca
     9361 ggaatcatca aagcaaatgt accttccaga atggcatttg cggtatcaag cggtacagat
     9421 tctcggacga tcattgattc taatggggca gaaaagctct tagggcgagg agatatgcta
     9481 ttcttgccaa tgggtgagaa taaaccgatc cgtgtgcaag gagcattcat ttctgaccac
     9541 gaagtagaac gggtcgttca atttgttaca gatcagcaag aagctcatta tgaagagaaa
     9601 atgatgccga cagatgaagt tgaaacgaca ggtgctccag aacagccaca agatgagctg
     9661 tttgaagaag caaaagcact tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa
     9721 agaagatttc ggatcggtta caaccgagca gcacgtttag tagatgaact ggaagctcat
     9781 ggagttgttg gcccgtcaga aggaagcaag cctcggaaag tattcattga gcaggaagaa
     9841 acatcagaaa cgttgccgga cgataatgac atgtaaaact tgtgtgatga agggttgaaa
     9901 aacgaataac caataaaaag acaaggcatg atgataccaa aagaaaaaat ggtttttttc
     9961 catcttttct aatacggtat gatgtcttgt ctttttagtt tttgtgagat taaagttcta
    10021 ttcgatttat ttgtgaagta ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa
    10081 ctttgagaaa aagagggaaa atactttgga aaaacagtcc atttatggct tgacgaatga
    10141 agaattaatc aattggttta tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg
    10201 ggaatggttg tatcaaaaac gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca
    10261 attgatcgaa aaattatcgg agcattttat catcaatcct ctaaaacaga tggtcgtcca
    10321 agaagcttcg gatggtacag taaaatattt gtttgaactc cctgataaaa acatgattga
    10381 gactgtactg atgagacaag aatatggctt gtcagtttgt gtgacgacac aagtaggatg
    10441 taatatcggc tgtacgtttt gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc
    10501 tggagaaatt gttgcacaga tcatgatggt ccaacattat tttgatgagc gcaatcttgg
    10561 cgaacgcgtt tcacatgtcg ttgtaatggg gatcggtgag ccatttgata attacgacaa
    10621 tgtaatggac tttttgcata tcatcaatga tgccaaagga ttggcaattg gtgctcggca
    10681 cattacagtt tccactagtg gattagcaca caaaatcaag gaattcgcta ataacggctt
    10741 gcaagtcaat ctggctattt ccttgcacgc gccgaataat gaggtgcgaa catcgatcat
    10801 gcggatcaac cgaagtttcc caattgagaa attgatggaa gctgtggatg agtatttaga
    10861 gaaaacaaac cgtcgaatca cgtttgaata tatcatgttg aatcaagtaa atgatagacc
    10921 agagcatgcg caacaattag cagatctatt aaaagataag aaaaaattag catatgtcaa
    10981 cttgattcca tataatccag tcagtgaaca tgatcaatat tctcgcagtc caaaagctga
    11041 tgtattgaga ttttatgatg tattgaagaa aaacggcgta aactgtgtga tacgtaaaga
    11101 acatggtaca gatattgatg cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac
    11161 agttgccaaa taatcgtatc ctactcgttt tttcaattac cataaaagga gcagttttct
    11221 taattaagga actgttcaac ttaaataaga gaaaagattc tatagcgaaa gctataaagc
    11281 tttttttgac aagaaaaacc ctcatcaagc aaagaaatgt cctcaatttg atgacagcct
    11341 gcttgatggg ggttttagca attatttaac tgattttctt atatccttgc tggctttctt
    11401 gtgtagcatg ataagtttct acgtcaagaa tggcctgttt aaatttttct cgggtgattt
    11461 cataaggcac atgtttaata tcatttgttg ccatggcttt atctaagatt gcttctaaat
    11521 cggtcgtgac attgagattc atgtcggtta acgatactgg aagttggttc tttttcataa
    11581 acacatagat tttatcaaac aaatcgaact gctgatccat catcaataag gtcagtacac
    11641 cataactgac agatgctccg tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt
    11701 aatagaatga gtgtgccata gcagaattat agttattgtt aactaaaaca gaaaccaatc
    11761 cggtagtaac aatgatatcc gaaacgactt gttcaattgc atatgaggga cgatcgtcgg
    11821 cactatcttt caatgcttgc gtaccataag tcaagagacg atcaatgcac atttttccga
    11881 tttggattcc taatctatcc gtgtagccta gatcatcgcc acgagcagaa aaagtagatt
    11941 cgacttcttt ggataaagca tcgccaatac ctgcccataa gtatttatca ggtgcttcgg
    12001 caataattgc tgtatcaatg aaggtgtgta caggtggttt tgaaggaaag aagagtccgt
    12061 ccattacgcc ttcttcgtta tagatgacac ataccgcagt gacgggcgaa cagttcgaac
    12121 caatagtggg aaaggtgaag actggtttag ctagtttttc accaatgact tttacagtat
    12181 cgcaagcacg gccaccaccg actgcaaaca ggacgtctgc tttttggaca ctttcatgct
    12241 ggatcaactg ttcaatattt ccataagttg aattaccccc gtaccagaga ctggcgacaa
    12301 cctctatttc ctgtgtcaaa gctactttta ttttgttttc tgcctttgaa agtgcagtct
    12361 tccctccaat cagcactact tttgtcccat attctttgac gattccattt gctttttcat
    12421 acgcatctgt tccaatggta taatttggta agaaaacact ttgactcata ttcatttcct
    12481 tctcgtaata tatattttga aacgacttcc atcgtttcag tcacccctta gggctattcc
    12541 ttattaaata acttttaaac cttggctatt gaattttgtt cctggataat agacttatgg
    12601 aaacggtcta tcggaacact gctaatttcc tttgtagcta tgactacagc aggaagcctg
    12661 catcccgact tattgattat catgcctcaa actcattagc tgtaccgttc acttcttaaa
    12721 ctatttctag taggaaatag ggtggctttt aagaagtaaa caattgagta ctattaagcg
    12781 agactgcggt tattcaataa gattcaggga taaacttcaa tagctaagta ttccaaaaaa
    12841 tttatgaaag gaggaccttc catgaaatta tttattggtt tagacgttag ttctcaaaaa
    12901 ttagatactt gttttttaac agactccaaa gaaatcttgt ttgaaggttc acttagcaac
    12961 gatttaatcg gagccagcga aatcaaacaa agaattctcg aataccaaga aacctttggt
    13021 ttctaccaaa ttgtcatagg tatggaatca acttctgttt atagtttcca cccagcaatg
    13081 tttttctact tagatgaaga tttgaagcta ttacctgtcg aagttactgt agaaaatcct
    13141 tatagaatca aacagtattc aagaatgttc gatcaggata aaacagataa aattgatgca
    13201 cagatcatag ctgattatct gcgagtagat ctccatacat tgtctcctat taaagaagaa
    13261 gtttatgttg gacttcaacg actaacaaga tctcgttatc aattagtgac acaaatggta
    13321 gaagcaaaac aacatttttt agaaaatttg acgtataaat gtaatacttt atcaaaagaa
    13381 cttgcgaatg aagataataa aacttccata ttcggagctt cgattatgaa tctacttaca
    13441 gaaggcatta ccttagatga attttcagaa atgcctctgg aagcggccgt tgaattactt
    13501 caaaagctag gaaaaggtcg attcaaaaat ccagagcagc ttgtcaaaag tattcaaaaa
    13561 gctgtacgta gttcttatcg tttaggtaaa gtaaccaaga attccattga ccttgtatta
    13621 ggtataatcg ccaatgaaat caagtttcta aaaaaacaga ttaaagaaat tgaaaaagcc
    13681 attactgctt tacttgaaac aattccagaa gcccaatgct tattaagtgt cccaggatta
    13741 ggagctgttt atactgcggg cttaatcgct gaaattggtc aaatcgagcg atttgatgat
    13801 caatccaaat tagcgaagta tgctggtcta acttggacta aaaatcagtc gggaaactct
    13861 caatctgaaa acacgccact aaatcgttct ggaaatcgct attttcgtta ctacttaatt
    13921 gaagccacca atcgagtaag aagcacactt ccagaattta aagagtacta ccaaaaaaag
    13981 agaaatgaag tacctaaaca caaacataaa cgagcgctcg tcttaaccgg aagaaaattt
    14041 gtacgcttga tcgatgcgct actacgcaac ggtcaattct atcagccagc gaaggtggtg
    14101 atagaaaaat aacgtaaagt tatttgcgaa aatcttcgtg atcaacccga aaaaaatttg
    14161 attttggtcg ggtctagttc agcgcggtct gatttttcaa aatctaactc atattctaaa
    14221 atttatatct tgacttatta ccattaggct tcatttccat agctgccacc attttttcca
    14281 attctttgtt tgttcgtcca ttgtttctgt tgcttcagaa agagtcgttg aactattctc
    14341 tgaagactct tccgtataag tcaactgcag ttgctcctga agtttttcga tttgttggtt
    14401 ggcttgcagg gtgagttgtt gttgctggtc gagtagtttt tgtatatgag aattattttg
    14461 ctctttgagg gcaagttgtt ctcgtaaaaa ttcattttct tcacgcaact gatctagcaa
    14521 cttgtttgca accacgtttt tgtttggtat ataagcattt ttatcgttgt tttgttcatg
    14581 tttatgcaac ttatctagca acctttgatt gtctaagttg cgagcaagtt gcaatactcc
    14641 agaacgcaat acaaccttat aaccacgctc atttttagct atcatggaag aatctaattt
    14701 ttggatatgt ttcgatattg cttgcctact catcttaaaa agatctgaca attcctttat
    14761 tgtaaaggtt tcttgtggtt gcatactggt tgcctcctag gttgctactg gaataaatta
    14821 tctaaatcag ataataaact ttttttctct ttttccgaaa gtgcggactc tgtttgtttt
    14881 tcaagagctt ttttctcttt ttctagttgt ttgatttgtt ggaggagttc aagttctcgt
    14941 ttcttctgtt tgattttttc gttaattgtt gtagcgggtt cttcgtattc tttttgttta
    15001 tcagctaaag ccaatgcttt attttggtct tctttggttg gtgcatgttt gttaaagtcg
    15061 tctgcttttt tgatctcagg tttgaacgta aattgatagc caataacagg ttttccccgt
    15121 ccttttccgt atttcttttt gattgttagt cctttgaaga ttgcagttag ttcttgacgt
    15181 ataggtttta taactcgttt atctatatca ggttgcttat aacttttagg aatatctaat
    15241 aattcaagaa agtcttcttt ggagaaatat gcgaaacctt tggttctgta ttgctttaac
    15301 agacgaaaca tagtctttgc atagccactt tgtagctcgt tgaattgttg taaagaatag
    15361 cgtacccact cgtctaaatt atttaacaaa ggcagtgctt tttcgtaaat tcgtatatct
    15421 acgtaaggat tttctacgtc cccgttgatt ttaaattctg taaacattac aaacatatcg
    15481 taagaaagcc cagactcact tctacgacca aagcgtaaag ataagatttt ttcataagtt
    15541 gcttttaaat cttctacaaa tcgtacattt gcagttgctt tgtagttact taaatctttt
    15601 agttggtcaa acgtaaaacg aactgtctta tccccttttt cacgcattct agacacgatg
    15661 gaaaaaaaca aattcatttc aaccggtgta aattttctta aaggaattgt atttaattca
    15721 tggtggtatt ttacaatctc attagccata taatcacctc aatccaatta tgaatgacat
    15781 tttttaaatg tcaagacatt catatttgac gttcaaacag acaaaatgtc cttcataaac
    15841 agacaaaatg tccttcataa acagacaaaa tgtccttcat aaacagacaa aatgtccttc
    15901 ataacattct gtatccattg gtagagtaag gacacagctt acggtaaaga ggtttaaaaa
    15961 gaggtttaaa aagagatata aaaagagggg ggctaatttt cccgcctaaa aaccacttct
    16021 tttttcttta aacaggttcg cgcatttttc aaaactgcca atccaaaacc ttgcttccta
    16081 cggtcgccaa aaaggtgtga tcgctacgct ctcacattgt actgcgcagt cgcctaaagg
    16141 ctcctttgct aaaaacatgt tggtaaagag gcctttgagc ggttctgaat gcttatctaa
    16201 gccgttttaa gacagtcttg gataaaaatc cttatctagc tttaaagcgc cttacaggcg
    16261 gtcagggcaa gccctaacaa ccctaaaata agcgatactt aaaaacacca cacaagttta
    16321 attttttaag atataataac ttgtcgccta tccgacagtc ttgcgactgg aaggaggtgt
    16381 atctaatgtt tgaattgttc atttgccccc ttcttataga agtttgtgtc tctttattca
    16441 gttattggtt gaataaccga aacaagaagt aaaatcaata aaggcgacat caacctgaaa
    16501 aaaagcccca gagaatccga cctctctggg gctttcgtgt atctaatgtt tgatcatttg
    16561 catgtttagt ttaacatgat tgccgatcaa attcaatttt gctgttgctg atctaaccat
    16621 tccttgacac tttttagata atttaatgcc gtttcttttt tcgttggatt ttgtatgttc
    16681 gttgcttgct gaagcagtgc tttataacgt tcgtaggtaa ctgattgttg ccgttctttt
    16741 cgttcctgtt cactagttga aaaagggatt gtatcactga ataaattata acaagcttct
    16801 tctgtctgcg tatctttaaa atattgcacg tcttttttgg ttcgctcata gttgtcttga
    16861 acctcttttt gctgtttttc tggcaagttt tgataaagac gagtgagttt ttccatgttt
    16921 ttatccgtca aacgtttttc ttgattcaca aaaatatcgt tcatttcctc ataacaagtg
    16981 gtaaactctt ccattttttg tgttaacact tgctcctttt tctttttatc acatgctgct
    17041 tcatactttt gagtgatatc ccctaataaa atacttcttg aaatacgttt atttccctct
    17101 aaaacgccga ataaaccact taaaacgatt gataatgtaa atataacccc tggcaataaa
    17161 aacctcttaa atcgaatttt agagcctttt aatgaatatc ttgtttgata agccttatag
    17221 ctaagccaaa taattcctaa aatactggca aaaatgagta gatagggtaa atagaatgcc
    17281 atttctattt attctcccca taccagccaa aaggctaaca gtgtcatgat taagcaacat
    17341 aagggggcaa gaatatccat tgatcgctgc ataattactt ttttctgttc tttatttcgc
    17401 tggtttaata gcgcatggtg gaattttttg acttgtgaat caattgtagt ttgtattctt
    17461 tctttggtat aaggtgcaag aaaagcacgt tgtttcttta tttcattttc tatgtcttgt
    17521 aacgttttag aacgataatt cttgttggta gtctgctcct ctttcaacgt gttggtcatg
    17581 gtttcttcga gtcggtctaa tttccggttg ttcagtcgta agagttcgtt gttctcttcg
    17641 tacttctttt gcagtttcgc gaatgctagc tcgagctctt cgtagctcgt tggttcgttg
    17701 ttgattgtag gctcgttctc gtctgtccag ctcatgtaaa atcgtctcct tttcgtaatc
    17761 ctttcctagt ttgttggatc gtactttttt ctttttgtgg atcaattcgt aagtaaaatt
    17821 tttcccacga ttcaagcaat gaatgccgaa tgttttaaga gaatcacaaa attggttata
    17881 cgttcgagtt tttttgtttt tcattgtttg atcaatcgca aaccgaattt cgtctttcca
    17941 aacaggttca tttttttctt ttaatttgat ttcagacatg gttcgttttt cgggtttctt
    18001 ccctcgttca gtgattgtta agtcatgttc aagacaaatc tcgtcattta ggtcataaca
    18061 tttgtttaaa aatgcttgac catgggcttg aaatttgttc ccagtttcca gattgacgga
    18121 gttaatgaca atgtggttat gaatatggtc tttgtctgta tgtgtgtaaa tcgcgatttg
    18181 gtggtcaggg gctatttttt tcgcatactc tgcccctagt tgattggctt tttcagcggt
    18241 aatttctcct ggtcgaaaag actggatcaa taagtgtgct tgtacacgat cgtcttttcc
    18301 atacagcatg cgaatttgtt tcatttcgct tttggcataa tcaatgtcac agtttatccc
    18361 tgttttgacg gttgctcgtg gttcggcgta attgatcgct cggctacaag aagtggttcg
    18421 gcttacttta actgttgcca tatcttttgt agctcctttt gcatgatttt taggttttcg
    18481 gataagcgtt gggcgtcgcc aggatcaacg tcgtgttggt gtgtgttgca ccacttggca
    18541 atttgattga tattcccgcc agctttggct aaatcgcgcg cgattgcctg agcaatgtct
    18601 ggcgccactt tcggtgtcac cagacgcgcg ttttgtgcct tggctttcac gaaagccggc
    18661 acactcattt gcaaagcttc agctgactgc ttcagctttg caaattcgga ttcgctcact
    18721 cgaaaactga tttgttttgg ctcggatcga taggtatatt ttttagaatg attgctagcc
    18781 aaatattgat tttgttcgct cataagtccc accctttcag tacgtcctac ggacgtatcg
    18841 ttcgcaatac cattgtacct aaaaaggtac aataagtaaa gctcactaaa gctcactaaa
    18901 gggcttggca agctctatat ttgctagcca aatacctacg tatttggtgc aaataaccgc
    18961 ttgtcaaagg ggcgcaagct cccccttgaa tccccctccc ccccactctc cacaatacaa
    19021 aaaagactag caaatgctag ccactttttg taaagtttcg cttgtttcac cttcggtgaa
    19081 attgttgcaa atcaataatt aggtagagct acattttttt cgttgttcaa agattcttat
    19141 gccatttact attaataaat ctataaatat gataattttt cggctctata atttatggga
    19201 ctgatgaatc agaattgatt cttcagtccc attttcattt tattccaaag aattaactcc
    19261 aaataccaat agaagcccat cctctatata cttgagattc cttactaaca atttcttgta
    19321 attctattaa agatttaggt aatccaaatt tatgttttaa aatatatctt ccaagaaaac
    19381 tacttaattt catactaact tcaccaacac tttttccctc actgatttct ttagaataaa
    19441 gaaagagctt ttcttttaag tcaggatagt catctatagt tgcttcattg tatactttac
    19501 taattgcatt taaaagtttt tcttctttag taaaatccat tataataacc tccctaccac
    19561 taccttctag gtgcccatgg accatgatta acccaaccat taacaataat ttttccaatt
    19621 tctcctttag cttgattcca atctacccaa catttttctt tgttacaata aagaccattt
    19681 ccatagtaag tagctgcatc aacttttatt cctgtaccga tgccagctag acaagttcct
    19741 aatattccta gaataacaca atgttttaat actttctttt tcatgattgt ttttcctttt
    19801 cgttttttta aaattgcttg ttatattaaa taatcttagt aattttatta tataacattt
    19861 tattatataa caatgattaa cgtcataaaa agtagttttg aattcataat cgtttaaatt
    19921 aaattataaa atcgttatat taagatctag tagacataat gtatatacta ccaagtaacg
    19981 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
    20041 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
    20101 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
    20161 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
    20221 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
    20281 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
    20341 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
    20401 tttgtcataa g
//
LOCUS       DAJSMK010000043        19570 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.045, whole genome shotgun sequence.
ACCESSION   DAJSMK010000043 DAJSMK010000000
VERSION     DAJSMK010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.045"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(166..330)
                     /locus_tag="ON488_001576"
     CDS             complement(166..330)
                     /locus_tag="ON488_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231774.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            625..1953
                     /locus_tag="ON488_001577"
     CDS             625..1953
                     /locus_tag="ON488_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HCR3231775.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2155..2988
                     /locus_tag="ON488_001578"
     CDS             2155..2988
                     /locus_tag="ON488_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HCR3231776.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            3004..3741
                     /locus_tag="ON488_001579"
     CDS             3004..3741
                     /locus_tag="ON488_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HCR3231777.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3896..4864)
                     /locus_tag="ON488_001580"
     CDS             complement(3896..4864)
                     /locus_tag="ON488_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HCR3231778.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5096..5929
                     /locus_tag="ON488_001581"
     CDS             5096..5929
                     /locus_tag="ON488_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HCR3231779.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLSPTQMDL
                     F"
     gene            5963..6802
                     /locus_tag="ON488_001582"
     CDS             5963..6802
                     /locus_tag="ON488_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3231780.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6828..7388
                     /locus_tag="ON488_001583"
     CDS             6828..7388
                     /locus_tag="ON488_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HCR3231781.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7587..9308
                     /locus_tag="ON488_001584"
     CDS             7587..9308
                     /locus_tag="ON488_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HCR3231782.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9473..10615
                     /locus_tag="ON488_001585"
     CDS             9473..10615
                     /locus_tag="ON488_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HCR3231783.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10631..11842
                     /gene="thiI"
                     /locus_tag="ON488_001586"
     CDS             10631..11842
                     /gene="thiI"
                     /locus_tag="ON488_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HCR3231784.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12415..13062
                     /locus_tag="ON488_001587"
     CDS             12415..13062
                     /locus_tag="ON488_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HCR3231785.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    13191..13407
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            13455..16100
                     /locus_tag="ON488_001588"
     CDS             13455..16100
                     /locus_tag="ON488_001588"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HCR3231786.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16410..17723
                     /locus_tag="ON488_001589"
     CDS             16410..17723
                     /locus_tag="ON488_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HCR3231787.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17713..18366
                     /locus_tag="ON488_001590"
     CDS             17713..18366
                     /locus_tag="ON488_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCR3231788.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18421..19113
                     /gene="radC"
                     /locus_tag="ON488_001591"
     CDS             18421..19113
                     /gene="radC"
                     /locus_tag="ON488_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HCR3231789.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19263..19463
                     /locus_tag="ON488_001592"
     CDS             19263..19463
                     /locus_tag="ON488_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCR3231790.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         6587 a         3302 c         4150 g         5531 t
ORIGIN      
        1 gtcgtaggtt cgagtcctac tgccggagta aataaagctt atgcaaagaa aaagaaatcc
       61 aatcacttgg gtttcttttt cttttattat tatgatgaat caagctttct gtttttgtca
      121 cgtatgttgt aatctttacg aaagagtaga gttggctact cataatcaac catacttccc
      181 atcatcgcta aatacgaaat aaatcagcat tcctacacca atcaaagcac aagctgcacc
      241 aagaaaaggg atgacattcc caaagttatc tgtattcata agtatgccac cacccacaaa
      301 caaaaagccg ccagcaatca ggtttttcat tttattcatc tcctttctta cgttatagta
      361 tttccttctt tcaatgagta ttttgaaagc tatcttattg tatgatgttc ttctaggcct
      421 cttctttatt atacaggcca ttttcgttat ctcatagaaa tattcctttt tatctgaaaa
      481 ctattgtata ccgtatgaca tttttcttca tgaagttgta agtatattct cattcaaatg
      541 aaaatttcat catagaagag attgtatttc taaattctta agagtaaaat acgaagtata
      601 acttggattt ggaaggatga ttggatgaaa gctattacgc ctgatatgac aacaaaattt
      661 aacaaacagt ttcaagcaaa tatcaaacag caggcattgc agcgggcagt tgtgaagaac
      721 ggaattactg cttctgctga aaatgtttca gcacatgtgg agaatacacc ggtattttct
      781 atagatttgg ctacggggaa agtggctaat caaatgcaat cggggcgttg ctggatgttt
      841 gctgcactga acacattccg tcataagatg ctgaatcaat tccatttaaa agagtttgaa
      901 ttatcacaaa attacacttt tttctgggat aaatatgaaa aggcaaatta tttctatgaa
      961 aacatcattg caacaggaaa agaggcaatc gatagccgga aagtagcttt cttactcgct
     1021 actcctcaac aagatggcgg ccaatgggat atgatcgttt cattattcca aaaatatggc
     1081 gttgtgccta aatcggtgat gccggaaagt gcgaatagtt caaattctcg agatttgaat
     1141 aactacttga acaaattact gcgtaaagat gcagtagtgt tacggaaaat ggttgctcaa
     1201 ggagaaacat tagacgctat tgaagaaaag aaagaagaaa tgctagaaag catttataac
     1261 ttcttagcta tctcattagg aacacctcca aaagaattcg attttgagta ccgcgatgaa
     1321 gaaaagaact atcatcttga ccgaggactg acaccacaaa ttttttatga taaatacatc
     1381 ggtgtaaaat tagatgatta tgttagcgtg atcaatgcac caacaaaaga caaaccattc
     1441 aatcgttctt atacagtaga gatgctagga aatgtcgttg gcgggaaaga agtcaaatat
     1501 ctgaatgttg atatggaaac tttcaaaaaa ttagcgattg ctcagcttga agaaggagaa
     1561 tctgtttggt ttggttgtga tgtaggtcaa tcttctacta gaactagtgg catcatggcc
     1621 ttagatgctt attcaatgga tgatctattt gatacggatt ttacaatgac taaagctgaa
     1681 cgtttagatt ttggagaaag tctgatgacc catgcgatgg tattgaccgg tgttgactta
     1741 gtagacgggc aatcaacaaa atggaaagtc gaaaatagct ggggcgaaaa agttggaaag
     1801 aatggcttct ttgttatgag tgatgcctgg atggacgaat atacgtacca aatcgttgta
     1861 agaaaagatt tattgacgaa agagcaatta aatgcgttca atgaagaacc aattgttcta
     1921 tctccgtggg atccaatggg tgctttagca tagacgagta tttcaatgaa gagtatgtag
     1981 taaagataaa aagagctggc ttaagccagc tctttttatc tttaaagtcc attccctgtt
     2041 ttttatggtc cctgtgctat aattctaaat aaaggataag gattggaaat aatcctttta
     2101 tcattaaaaa tatgatgacg aagtagaata aaattgggag taggggggaa agtcatggat
     2161 atccaaactg ttttatctga tctgaaatta aatggtaaag tgattccagt tgttggtggc
     2221 gatgttaatc agacctatcg tataaaaacc gaacatcgtg cttatttttt aaaaatccat
     2281 ccgaatgtaa aaaaaggatt ttttgaagca gaagtagacg gattaaaaga actgtcagca
     2341 ttcgtacgtg taccggatac gtatatgcta ggtgaaacaa gtgaaggcgc ttatttgtta
     2401 atggaatgga tcgagccggg aaaaggggat caacgagatc ttgctgcagc tttagctaat
     2461 ctccatcagc aaacagcgcc acaatttggt tttcgtaaag ataactattt gggtacactt
     2521 gttcagaaaa attcttttga agaagattgg tggacttttt tctttaaaga tcggcttgaa
     2581 tcccagattt ctttggcaga agaaacgaat cgatggaatg tacagcgtca agaaaagtat
     2641 ctgcgattta aagaacgtgt attgaaatcg gttgaaccaa aaaagatcac tccacgcctc
     2701 ttgcacggag acctgtggag tggtaatgtg ttctttgacc agcaagggca tccagttttt
     2761 gtcgacccag ctgtttctta tgggaatcgg gaacaagata ttgcaatgag ccagttattc
     2821 ggtggtttcc gaccggaatt tttagatgct tatcaaacta tatttccatt agaaaaggga
     2881 tggaaagacc gactgccgat ttaccagtta tattatcttt tggcacattt gaatatgttt
     2941 ggagaaagtt acggttccca agtagatcaa ttactagaaa atttttaaga ggagggcgtg
     3001 tttttggcaa aaaaatatac caaaaagcat gaagtttcat attatgagtg tgacatcaac
     3061 caaacgatga catttccttc gatgttagga gtagttatca aaacgtctga agatcaaagc
     3121 gaccagttgg gaagaggcag tgaattcgtc aatagctttg gacttacttg ggtcatcacg
     3181 aattattcca tggagattaa tcgtctccct agagtcggtg aagtaatctc agtaacgact
     3241 caagccatgg agtacaataa gtttttctgt tatcggaact tctggatcca tgatgaagat
     3301 gggaaagaat tagtcaaaat agaatctgtt ttcgtattga tggattttgt gaatcgaaaa
     3361 atgagcagtg ttaatgaaga gatcattgct ccttttgaga gtgagaagat caagaaaatc
     3421 aagcgtcagg aaaaaattga aaagattgat tcgggcttca tgttgccata tcgtgttcgt
     3481 ttttatgata tcgatagtaa tcagcatgtt aataatgcga tgtattttaa ttggatcatt
     3541 gacgtattag gatatgactt tttgactacg catgttccag aaaaagtaat tattcgattt
     3601 gataaagaag tagagtacgg gaatgagatc gaaagccatt ttgaacaaat ccctatcgaa
     3661 aatggtgtca aaacaaaaca tgaaatccga atgcaagaac agctgtattg tgaagcaaat
     3721 attatatgga aaaataaata aaaaagaggt tgtgacagaa gggggcaact tcaagaaata
     3781 agaagaaatt tacgaaaatt gtttctcaaa tttttgtaaa ttttcgactt agttttcgaa
     3841 gaagctattt ttgtcacagc ctctcttttt aagtttagct attagataat gatgtttagt
     3901 tttggataaa cgaaatcaat tcttcacccg acaaaccata gtttacagca atcaatagtt
     3961 ttaaacgtgc tttttgacta ttaatactgt tacagaaaat aatccccatt ttttctagtt
     4021 cttttccccc gccttcataa tcataaacag gctctgcgat tccattgaaa caacgagaaa
     4081 caagtactac agggattttt tggacaagaa gcttttccaa agcagctaag gcttgtggag
     4141 ggagattccc cgcacctaaa gcttcgatta ccaaaccgtc tactttcgta tgggcgatgg
     4201 cttccaataa gtccccttgc atcccagcat atgctttaac gatcgggata gtcccatcta
     4261 cagcggaaat gtccagtcgc tttgtttcta aaagttcctg caagaataaa attcgattct
     4321 tagttactaa gccgatggga cccaatgtag gtgttcggaa agtagcaaca tttgtggtat
     4381 gggtctttgt cacgtagcgt gcagaatgga tctcatcgtt catgaccacc aaaaccccct
     4441 tatctagcgc ttcttcacaa cttgcgacac gaatcgcact ttcaaaatta taaaggccgt
     4501 cacttccaag ttcattactt gaacgcattg ccccagtcaa aacaattggt aatttgttgc
     4561 caatcgttgt atcaagaaaa aaagcagttt cttctaatgt atctgtaccg tgtgtgatca
     4621 ccactccgga tatacctgat gcataagcgg acaagatacg ttcttttaat accaacatgt
     4681 gagaaggcat gatgtgtggt gagggaagat tgaagatatc ttcaactaat aattctacat
     4741 gcttggggat tgtgatttct gcatctaata atgggtttgc cacatcagga ctaacaccgc
     4801 ccgtgagcat gttttctttc atggcgatcg ttccgccggt gtgtagtaca agtatttttt
     4861 tcattttaca gacttcctta cgaataattt tgcatagccg ttaaatctta ttgtatacta
     4921 tataaaagag ttttgctatc agtgaagaat aacgaatagc ctaacttatc ataaaaaagc
     4981 tgaccttatt aaaatggaaa agactcaacc ttgacctcct aatacaatgg agtatctggt
     5041 tgagtttctt ttacaagaaa gcagccaagg aaatcaatca cgaaggtggc cggaaatgat
     5101 cagaatcgga ttaacatcgt ttaaagaaca tgacaaatta actggtaaaa agaataacac
     5161 tctttatgaa tatgcagggt ttctaccctt agtggaatta gatactgcct attatggaat
     5221 tccccgaaag tcctcagttg agaattggat aagtgaagta cctgaatcat ttcgctttgt
     5281 agtcaaagtc tatcaaggaa tcagcggtca aggagactgg aagccttatt atcagaccga
     5341 agaagagatg attgcgcatt ttttagatgt tatgtcgcca atggtagatg ctggaaagat
     5401 gttttgcttt ttagtccaat tcccctcatc attcaaatgt acgaaagaaa atgtccagta
     5461 cttgcgcaaa cttagaaagt ggtttgaggg ttatcctgtt tctatagaat tgcgggatta
     5521 ttcttggtac agcgatgaat ttcttgaacg tacaagaaac tttatgtcta gagccgcttt
     5581 ttctttagcc atcatcgatg agccacagtt gctgaataca acgattcctt ttgatccatt
     5641 tgtcaccaat ccgaactttg ctctttttcg attccatggt aggaatgcgc aaggatggca
     5701 agcaaatgat aaagagtggc gtaaaaaaag aacgttatat cgttattcag aaaaagaact
     5761 gcaagaacta gcacatgaag tcaaagtagt tgattctaag acaaaagagg taggtgtgat
     5821 ttttaataat aattctggtg gtgatgcggc tgaaaatgca ttagcactgc aaaaaatatt
     5881 aaatatcaag ccagatggac tcagtccaac ccaaatggat ctgttttaag ggcttatttt
     5941 attcaagaaa ggggcgaagt ctatgatcaa agctattttt tttgatattg acggaacatt
     6001 ggtcaccaat cgttcaaaag cgttggaatc aacaaaacaa gcaattgaat atgctcggaa
     6061 aaacggcatt ttatgcggtg tagcaacggg gcgcagccca gtaaagatca aagaaatcat
     6121 tgatgaattg gaattagata tgtatgtcgt gtataatggt caactggttt ttactgcaga
     6181 tcgcacgatt atcgaccacc cttttgaaca aaaagtattg gaacatattg ttgaatttgc
     6241 agatgagaac catcgacaaa tcgtttttgg tgcgagaaat cggttagatg gatcaacgac
     6301 gatgctatta ggacaatcga tttttatcaa gcgactagtc agctttttac cgcgtaaatt
     6361 cccggtacgt ctgatgaaaa aaatcctcca ggtttttagc cctcaccgac aaaaggatcg
     6421 ttatgaaacg ttagagatat taaaagaacc aatttatcaa tgtatattgc tcagtccgga
     6481 gtcagaacag aaaaagttag aacatcgctt tcccgagtgt acgtttcagc gttcaaatac
     6541 gtatactgta gatatcatcc caaaaggtgg ttcaaaatta ctaggcatcc aagctttcgc
     6601 aaatgctgtc gaaattgaaa tggaagaaat tatggcattc ggcgatcatt acaatgatat
     6661 cgagatgctg aaaggtgtag gaattggagt ggccatgggg aatgctcaga tcgaagtaaa
     6721 acatgctgca gactttgtga ctcaatcaaa tgaagaagat gggatatacg aaggactgaa
     6781 acacttcggt ctgatttatt agtcaatgaa agaaggaaaa aatcagtatg gaagcagaga
     6841 caccttttca aaaagtagaa acattccaca aaacttttga tccaagaaga ccagagatac
     6901 ccacggcttt tacagaaaat gaagctcata cacgtgctgc gttcaaaata gaagaacttg
     6961 ttgaatttgt tgcagctact tcacctaata aagaacaact gcatgaagct gttatgctgc
     7021 tgcacgaagc attagataaa gcagaagaaa aaatacttgg taaaacacag tggggaagtg
     7081 atccgctggt tgaacaagta gatgcactga cagatatcct ttactttact tatggttctt
     7141 tttcattact aggaatagtg cctgatcgaa tattcgaaat cgtccatcag gcaaatatgg
     7201 ggaaattatt tccagatgga aaacctcatt atgaccctgt aacaaataaa gtgttgaaac
     7261 ctgaaaactg gcagatggaa tatgctccag aacctaaaat cgcggcagaa atccaacgtc
     7321 agattcaaga agcgattgct aagaagaaat ccgctgatat aggcatgtgc acaaatgaaa
     7381 aagagtgatc agagtttcac tatttttgtt atctttatac gatggaaaaa caaaagattt
     7441 tcgtttaagt tagtgaatgc atgaaaatag tatgctataa tctagaatag atgtcttttg
     7501 cacgagagac gtattatttg gatttatgcc aagcagaacg ccatctgttg cataaaagat
     7561 gcatactgaa aacggaggaa ccataaatgg gaaataatgt tatcatcgga atcgtcattg
     7621 caatcattat agtcgccatt gtcgtctttt tggttagtta cttgatgaag aaaaaaaacc
     7681 aagatcgatt ggatgcctta gaaaaacgca aggaagaatt atttgacttg ccagtgattg
     7741 aagaagtcga tgatgttaaa aaaatgcatc tggttgggca aagccaaaat acctttcgtg
     7801 aatggagtca aaaatggaat gacatatcta cttcctcgtt cgctgaacta gaaagtcaaa
     7861 ttttcgaagt ggaaaacctc aatgaaagtt ttcggttctt aaaaggaaaa aaagcagttg
     7921 ttgaagcaga agctacaatg gaccaaatgg agaaacaagt gacggaaatc cgtgaaggtc
     7981 taaaggaatt gcgggaaacg gaagaacgca actcactagc tgttcagcag gcacttgacg
     8041 tctatgaaga actgaaagaa aaagtcagag aagacgagca tgaatacgga ccagctcttt
     8101 ttgaattgca aaaacagatc aaagtgatcg aaaaagaatt tacgcagttt gtgactttaa
     8161 acacttctgg agaccctgtt gaagcccgcg aggttttgga taaagcagaa aaacatacgt
     8221 atgaagtgga agctctgatg aaaaaaattc caccgctgta tgaggagctc cataccactt
     8281 tccctgaaca acttgaagaa atcagtgata cttacgagaa attgatggaa gaacaatatg
     8341 tattcccaga agaagatctt gctgaagata tcgcaaaagt aagtcgaaga attgaaaatt
     8401 cattagccaa tcttgaaaaa acagaagttg aaacggtcga atttgaaaac cgtgaaacag
     8461 ctgatttgat tgattcgtta tatgatatct tagaacggga aatggaagct cagagatatg
     8521 taaaaactaa ccaatcaacg attgcagagt atatcaaaca tacaacaaag aataaccgtc
     8581 aattattgat tgagctggat cacacatctc aaagctatac attgaaccac aatgaaattg
     8641 gccgtgtacg aggtttccaa accgaagtgg aagaaatgga acgtcaaaat gaacagatga
     8701 ttccacagat ccgtcaacac gaaattcctt attcagaagt gcgcacgttc tataaaacag
     8761 tcttcaaagt cttagaagat atcgaaaagc aacaagtaga gatcgacgac tcattacatg
     8821 aattgagaaa aggcgaaaaa gaagcgcaag aaaagatcga tacattcgaa ttcaaattgc
     8881 gcagtttgaa acgttttgta gaaaaacaac gtttgcctgg cttgccgaat gattacctag
     8941 aattcttttt tgttgctact gaccgtattg aagaactaag tgttgtcttg aataaaattc
     9001 gagtaaacat ggaagaggtc aatcgtttag ttgctctatg tgaagaagat ctagaattat
     9061 tagataagaa gacacatgat ttagtagatg cagcagcatt aacggagcaa atgctccaat
     9121 atgcaaatcg ttatcgtcat acacacgaag aagtgagaga agcaattgat aaaagctact
     9181 atttattcaa taaagaatat cactatcaag aagcattaga cgaaatcggt acagcattag
     9241 agcgagtaga acctggtgct ttcaaacgca tcgaagattt ttattttaat catccagact
     9301 tagtataaag caaaaaagtt agtaaaccag caagagcaag acggattatt gtcttgttct
     9361 tgtctttttt tgtatatttg aaaattgaaa caagtgaaaa tttcacctgc tcttgaaagc
     9421 accttggaca accgttataa tagaaaagaa tttcaaaaaa gaggggtttc ttatgatata
     9481 ttttgataac agtgcaacaa ccccaatctt tccgcaaagc ttagatgcat atgtaaaaac
     9541 cagtcagcgg attattggga atccatcaag cttgcatgat ttaggcaatc aagctaaccg
     9601 gttgttgcag caagcaagaa agcagatcgc tgatttgatc catgtagaac cagaagaaat
     9661 ctattttact tcaggcggaa cagaaggaga taactgggta ttaaaaggaa cgatgatcga
     9721 aaaaagagaa tatgggaatc atatgatcat ttcaggagtc gaacatccgg ccgtcagcga
     9781 gacagcagaa caattaaaag aattaggaat cgaagtaagt atcgccccag tggataaacg
     9841 cggatttgta cgtgtcgacg aattgaaaga attaataaga aaagagacag tattagtctc
     9901 tgttatggct gtgaataatg aagtaggatc gattcagccc atccaggaaa tcagtgatct
     9961 tttggatgat tttcctaaaa ttcatttcca tgtagatgct gttcaggcga ttggaaaagt
    10021 accattctcg caatggttga cagaaagagt tgattttgca acattttcag ctcataaatt
    10081 ccatggccca cggggaactg gtttcattta ttggaaaaag ggtcgtcgtt tagcaccatt
    10141 actgacaggt ggagggcaag aaagaaatca gcgaagtggg acagaaaatg ttccaggtat
    10201 tgtggctatg gttaaagctt tacgtttatc attagagata aaggaacaaa aacctgagca
    10261 gacacaacgc ttaaaagtag ctctaatcaa tgcgttgaag acgtatgaga aagtgacgat
    10321 tttttcagaa ggaactgact atgcaccgca tattttatgt tttgctctaa aaggaattcg
    10381 cggcgaagtt ctcgtccatg ccttagaaga aaaacaaata tttgtttcta ctactagtgc
    10441 ctgctcctca cgtaaacata tggcaagcag tacattgcac gcaatgcatg taccaaatga
    10501 tctggctaca tctgctgttc gaatcagctt agatgaaaac aattcgcttg cagaagtcga
    10561 gcaatttatg attattttca agcagcttta taagaaattt tctgcaatca attaaaagag
    10621 gagtgttctt gtgaaataca gtgaaattat ggtccgttat ggggaacttt cgacaaaagg
    10681 aaagaatcga aaaagcttta tcatgcaact agcacaaaat gtcagacaag ctttgaaaga
    10741 ctttccagaa atcaaaatcc atgctgatcg ggaccggatg catcttttat tgaatggcgc
    10801 agacgggcag ctagttattc caaaactagc aaaaatattt gggatccaaa atttctctcc
    10861 aagtattcgt gtagaaaaag atgtcgaagt tttgaaacaa gctgttcaag acatcatgaa
    10921 agaaatttat actgggaaag aaacatttaa aattatcgct aaaagaagcg atcaccaatt
    10981 tgaattgaca agtaatgaat tgaatcaaac attaggtaat gctgtttttg atattttccc
    11041 gcatatccaa gttcaaatgc gtcaaccaga tattccatta cgtgtagaga ttcggcgtga
    11101 tggcgcttat ctatcgtatg aaacgatcaa gggagctgga ggattgcccg taggaacaag
    11161 cggaaaagga atgcttatgc tttctggggg gattgattct cctgtagcag ggtactttgc
    11221 catgaagcgg ggagtggaaa ttgaagctgt tcattttgct agtccgccgt atacaagtga
    11281 acaagcactg caaaaagcaa aagatctaac agccaaacta gcaccttatg tgggaacgat
    11341 ccattttatc gaagtgccat ttaccgagat tcaagaagaa atcaaaaagt cagtgccaca
    11401 aggatattgg atgacaatta ctcgtcgaat gatgttgcgt ttgaccgatg aaattcgccg
    11461 tattcgtcat ggtttagtca ttttgaatgg tgaatcatta ggtcaagtgg cttcacaaac
    11521 tttgcaaagt atggtggcta tcaatgaagt aacgaatacg ccaatcattc ggcctgtagc
    11581 gacaatggat aaacttgaaa tcattgaagt agcagaacag atcgatacat ttaatctttc
    11641 tatccagcct tttgaagatt gctgtacgat ttttgctcct ccacagccaa aaacacgccc
    11701 tcaactggaa aaggtccatc aatatgaaga gcgtttagca atagatgaaa tgatccaacg
    11761 agcactagct ggcttgaaga tggaagagat acaagcagaa tcgtctaatg aaaaaactga
    11821 agaattttca gaattgctat aagaggttat gaaaatagtg ttttgaccag agtattagag
    11881 aaacaaaacg aaaaaatagc tccatgtatt ttaccgtttt tgaactaatg tcgaagatta
    11941 gctgattgaa taccatttat caagaagtta tggaaaagcc ggttcttttt tactaactga
    12001 aaaataaaat tttatttaga gatcaagcta cagttgataa atgatataaa aaagagaatt
    12061 tcccatgaaa tagcgaggtt gtgacagaag tgggcagctt caagaaataa gaaggaattt
    12121 acgaaaattg cttttcaaat ttttgtgaaa tttcggctta tttttcgaag aagttacttc
    12181 tggaacaccg tgtatcagag gttgcgaaaa agctgccctg catcaagtaa taagaacagc
    12241 caaacaaaaa tagttcctca tattttacgt ttggttgagc ttattaccgc agatgcaagc
    12301 ttttgaacac cgttttattt gtctcacacc cttttccttc ctacttgtaa ccttgctccc
    12361 gtgttagaaa catgttacac taaatatgtg aaattattaa caaggagcgt cgttatgcga
    12421 gaaaaaacag atacactgcc aaaagcaact gcgaaaagat tacctttata tttacgctac
    12481 ttgaagatgc tggatgactc aggtataagt agaatcaaat caaatgagtt cagcgaaatc
    12541 acccaaattc cttctgcaac gatccgcaga gacttctcgc aattaggcga gctaggcaga
    12601 agcggatatg gctatgatgt cccttttctt atcgatgtat tcaataatat ccttaatact
    12661 aaagaagaaa aacgaatcgc attagtagga tatggaaatc ttggcaaagc attgaaacac
    12721 aacaatttta gaagaaatga aaatctaaat atcgtgtgcg tctttgataa tgatccagca
    12781 ctgatcaatc gagtaattga tggagaaatg atctatccga ttgatcgttt cgcggagata
    12841 gccaaagcaa aaaatgtgac agtagcaatc tctacggtac caagtaaata ttcacaatct
    12901 gctattgatg aaattgtcaa aggaaatgta accgctatac ttaattttgc gcctgacaga
    12961 gtaactgtcc cagcttatgt caatgttcaa tacattgatt tgacaaccga gttgcagacg
    13021 cttatttact ttgatgagaa ttactcagaa gttttttctt aggaaaattt gagtaggctt
    13081 attgatcttg cgagaactcg tcgtaattct ttcaaaaatt ttttagtact aaatgaagtg
    13141 gttttttcac gaccacttgt tgactaaaaa aaaaaaccat tgtagaatga agcataacgc
    13201 tgaacaagag gagtaactgg cacattcatt cttagagaga gaactatctg ctgaaaggtt
    13261 ctcaatgaca accagtgaag gtagcttggg agtttctgtc ttgaatggag tagagataga
    13321 cgagtcgtga tcgttaactc acttgagagg caataatgat tgattattgc aatttaggtg
    13381 gtaccgcgta aatcatacgt cctagaatac gaaagtattt taggacgttt tttagtttaa
    13441 aggaggaaaa cagcatgacg gaagaaaata acctatcaac aaaatataat ccgcaagaag
    13501 ttgaagctgg acgttatcag cattggttag aacaagattt gtttaaaccg agcggagata
    13561 aaaaagcaaa accttattca atcgtaatcc cgcccccaaa tgttactgga aaacttcatt
    13621 tagggcatgc ttgggatacg accttgcaag atatgctgat tcgtcaaaag agaatgcaag
    13681 gatatgatac tttatggctg cctggtatgg accatgcagg aatcgcgaca caagcaaaag
    13741 tagaagcgaa gcttagagag caagggattt ctcgttatga tctaggtcgt gaaaagttca
    13801 tcgatcaagt gtgggaatgg aaagaagagt atgcgagcca catccgcgaa cagtgggcta
    13861 aaatgggctt atctttagat tacagtaggg aacgttttac attagatgat ggattatctg
    13921 aagcagtacg taaagttttt gttaccttat acgaaaaagg tttgatttat cgtggtgaat
    13981 atatcatcaa ctgggatcct caagcacgaa cagctctatc tgatatcgaa gttattcata
    14041 aagatatcga aggcgccttt tatcatatga gctatgaact agcagatgga tcaggcgtag
    14101 tagaaattgc gacaacccgt ccagaaacga tgttgggaga tacggcgatt gctgttcatc
    14161 cagaagacga gcgttatcaa gcgctcatcg gcaaaaaagt gattctacct ttagtcaata
    14221 aacaaatccc aatcattgca gatgaatatg tagatatgga attcgggaca ggtgtagtaa
    14281 aaatcactcc agcacatgat ccaaacgact ttgaggtagg taatcgtcat gatcttccac
    14341 gcgtaaatgt tatggatgat gatggtacga tgaatgaact agcaggaaaa tatgctggaa
    14401 tggaacgttt tgctgctcgt aaagcaatcg tgcaagatct gaaagaaatc ggtcgattga
    14461 ttaaaatcga tacgatgatc cacagtgtgg gtcattccga gcggacaggt gtcgttgttg
    14521 aacctcggct gtctactcaa tggtttgtaa aaatggcgcc gttagcgaaa aaagccattg
    14581 ataaccaaga aacagatcaa gcagtggaat tcttccctcc aagattcaat caaacgtttt
    14641 tacgttggat ggaaaatgtc catgattggg taatctcacg acaattatgg tggggacatc
    14701 aaattcctgc atggtatcac aaagaaacag gtgaaatgta tgtagggatg gaagcaccag
    14761 cggatagtga aaactgggta caagatcctg atgttttaga cacttggttt agttcagctt
    14821 tgtggccttt ctcaacaatg ggctggccag atacggaaag cgaagattat aagcgatact
    14881 tccctactag cactttagta accggttatg acatcatttt cttctgggta agcagaatga
    14941 ttttccaaag cttggaattt actggcgaac gtccatttga gaatgtcttg attcatggat
    15001 tgattcgtga cgaacaaggg cggaagatga gtaaatcatt aggtaatgga atcgatccga
    15061 tggaagtaat cgaaaagtat ggagcagatg ctctccgctg gttcttatcg aatggttctg
    15121 caccaggaca agatgtccgc ttcagctatg aaaaaatgga tgcttcttgg aactttatca
    15181 acaaaatctg gaatgcttca cgtttcgtta tcatgaatat cgaaggaatg accgtagaag
    15241 agatcgattt atctggagaa aaatcagtgg ctgaccggtg gatccttact cgtttgaatg
    15301 aaacgatcga acgagtaact gagctatttg atcgttttga atttggtgaa gcaggtcgac
    15361 aactgtataa ctttatctgg gatgattttt gtgactggta catcgaaatg agtaaagaag
    15421 tactttatgg agatgatgct gtttcaaaac aaaccacccg tagcatctta gtccatacac
    15481 ttgatcagat cctacgttta ttgcatccaa tcatgccatt cgttacagaa gaaatatggg
    15541 aacatattcc tcatcaggga aattctctag tagtggcaga atatcctgtt gtacgtccag
    15601 agtttgatga tgaaacagct tctaaaggga tggaagtatt gaaagaattg attcgagccg
    15661 ttcgaaatat tcgttcagaa gtgaatacac cattgtctaa accaattacg ttgctaatta
    15721 aaacaaacga tgctaaaatc gatcaatttt tagttgaaaa tacaagctat atcgaacgct
    15781 tctgtaatcc cgaagagttg acgatatcaa gtgagatcac tgcgccagat ctagcgatgt
    15841 cagctgttct gacaggtgca gaaatcttct tgccgttagc aggattgatc aatattgaag
    15901 aagaaatcaa acgattagaa aaagaactgg aaaagtggac aagcgaagta aaacgtgtcc
    15961 aaggaaaact ttctaatgaa cgttttgttt ctaacgcgcc ggaagaagta gtagaggcag
    16021 agcgtgcaaa agaaaaagat tatttagaga agcaaacggc tgtcaaagaa cgaatcgaaa
    16081 gtttgcgtac tattcaataa gaatagaaaa agagagtgtg aaatcagcta gctattacta
    16141 aaagctagct gattgaacat cgttacagga aagagtttga gcctcactct tagcttcgat
    16201 tcataaggag atgtgacata aattttgtcg catctctttt ttagtctact cttattatgt
    16261 aggagaagga gggaggtgga tcatgtatca agagtcaata aagtagttga taaaatcgtt
    16321 cctctctctg tttcttttct ctttgtcata cttttatttt tcttatgtgt tctatttgtt
    16381 ataataaaag agaaatgggg gaattgttga tgacgattga agaagcaata gaatggatcc
    16441 atagtcgatt accatttggt tcacgtcctg gccttgaccg agtcgaagct ttattagaag
    16501 tggtagggca tccagagaga aaagtaaaaa cgatccatat cgctggaaca aacggaaaag
    16561 gttctactgt agcttatttg agaagcctat tagaagaggc tgggctgaca gtaggtacat
    16621 ttacttcacc ttatatcgaa acgttcaatg aacggatcgc aatcaatggc aaaagcattc
    16681 cagacaatga tttgatccag cttgtaaaaa aatatcagcc actgatcaaa caacttgatc
    16741 aatttgaagc agtagctggt attactgaat tcgagacatt aacagcaatg gcatttgatt
    16801 attttttgat gaagaaagtg gacgtagcga ttatcgaagt tggcttaggc ggcttattgg
    16861 attctaccaa tgtagctgta ccaatgctga cgggaataac aacgattgga cttgatcata
    16921 ccgaaatact tggagataca attgaagaaa tcgctgcaca aaaagctgga atcatcaaac
    16981 aaggcgttcc agtagtaaca ggaaatattg ccccagaagc ttttactgtc atccaacaaa
    17041 cagctaaagc aaaaaatgca ccgctttatg tatacgggga aaattataaa ataaactatc
    17101 tgcatcctga tgagatgtgg ggagaagtat ttgaattttt taatgaaata ggaaagatcc
    17161 ctcaattaac cactccgctt ttagggcaac atcaagctga aaatgcagga gtagccatcg
    17221 aattgtattt tgtttactgt caattggaaa agctgccttt ccgagaaaaa gatgttttga
    17281 agggattgaa gaaatctcga tggccaggaa gaatggagcg tttgagtaac gagccattag
    17341 ttgttttaga tggtgcccat aatacgcatg caatgaaccg gcttgttgag aatttgaaaa
    17401 aagaattcaa aggatatcaa atcaacattt tgttttccgc cttacgaact aaaaatgtta
    17461 gagaaatgct agaacgattg cagcaagtac caaatgtcca tatttatttg acgacctttg
    17521 aacatccaaa agccatcgaa ttaagtgaag tatcagattt agcaagtgag agagtatcaa
    17581 tcgtttcatt gtggcaattc ggattagcag atatattgga aaagatgaca aatgaagacg
    17641 tattagttgt gaccggttca ctttatttca tttcagaagt tcgccattta ttaatacaat
    17701 taggaggaga tcatgaagta taatgcagtg atttttgaca tggatggttt gctgttcgac
    17761 acagagttag tgtattacga agccacacaa gtagtagcag acaagatggg ttttccttat
    17821 gataaagacc tgtatttaaa attcttaggt gtttcagatg aagaagtatg ggcgaattat
    17881 catatgattt tctcggaatt tggcaaaaca agtgtacaaa gattcataga tgattcatac
    17941 caggaaacgc ttgaacgttt ttcgcaagga gcggtacaaa tgaagcccgg tgtgttggaa
    18001 ctcctctctt ttttagaaga acatcagatt cccaaagttg tcgcttccag taaccaacga
    18061 gcagtcattg aacttttatt gaagaagaac aatctgtttg aacgatttga gacgattgtt
    18121 tctgcagaaa atgttcaacg agcaaaacca gacccagaaa ttttcttgtt agctaatcag
    18181 aagctaggta cagcgaagaa agaaacattg attttagaag attcacaaaa tggtatttta
    18241 gcagcttctg cggctgagat cccggtagtc atggtaccag atctgcttcc accatcccaa
    18301 gaattgatca aaaaaacagc tggggttgtt tcttctttac atgaaatccc tgcattgtta
    18361 aaataaaaat ccatctcttt tcgtatctta ttttagataa gatagaaagg agatgttttt
    18421 ttgggaaaac gattgatcaa agaagtacct actagctctt taccaaggga acgtatggaa
    18481 atttatggcg cggaagcttt atcggatcag gagcttttgg caatcttact gcgtaccggt
    18541 caacaccctt atagtgtgat gtcgattgct ggaaatctgt taaaaacgtt tggaggactg
    18601 gcctctttac gacaggctac tttgcatgag ttagaagaga ttcgagggat aggacgcgtg
    18661 aaagcaatcg aaatcaaagc cttgatcgaa ttaggtcgac gaattcagac ggatcatgaa
    18721 agagcggctc caccggttcg taccagctac gaattggccc agcaattgat tctggaaatg
    18781 aaagatcaca aacaagaaca tttggtttgt atttatttgg acacgaagaa tcaagtgatc
    18841 ttaaaaaaaa cagtgttcat cggttcgctg aatcagtcag tcgctcatcc tagagaaatt
    18901 ttccattatg ctgtacgtta ttgtgcagca aggatcgttt tagcgcataa tcatccttct
    18961 ggtaatgtta ttccatcgca gcaggatatg aattttacca aaaggataca aaagtgtgga
    19021 gaaatgatgg ggatcactgt actggaccac ttgatcatcg gacgcaaacg atattttagt
    19081 ttgagagaag aaggaatgat ggaagagaag taagttgctt tcttgcaaaa aaaatgaagc
    19141 aagtgtacaa ttatattgta attttgtttg ggaatagaag ttgaaacatc tgttgcacct
    19201 ctatcgtaca cgagcaatgt tacaatttaa attagtgctt ttggcacgag gaggatatta
    19261 ttatggaaaa cggaacagta aaatggttca acgctgaaaa aggatttgga tttatctcac
    19321 gtgaagatgg aagcgacgta ttcgttcact tctcagctat ccaaggtgac ggattcaaaa
    19381 cattagaaga aggtcaagca gtgactttcg acgttgaaga atcagaccgc ggcccacaag
    19441 ctgcaaacgt tgtaaaagct taattttatc tgtaaatcaa attgatggta gacatcaatt
    19501 tttacgagag aacaaagcga gtaacaaaaa tacctgccac aagagacaat ttctcttgtg
    19561 gcaggtattt
//
LOCUS       DAJSMK010000044        19274 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.046, whole genome shotgun sequence.
ACCESSION   DAJSMK010000044 DAJSMK010000000
VERSION     DAJSMK010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19274
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.046"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..1505)
                     /locus_tag="ON488_001593"
     CDS             complement(<1..1505)
                     /locus_tag="ON488_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR3231791.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKA"
     gene            complement(1489..1881)
                     /locus_tag="ON488_001594"
     CDS             complement(1489..1881)
                     /locus_tag="ON488_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3231792.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            complement(1968..2465)
                     /locus_tag="ON488_001595"
     CDS             complement(1968..2465)
                     /locus_tag="ON488_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCR3231793.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(2582..2806)
                     /locus_tag="ON488_001596"
     CDS             complement(2582..2806)
                     /locus_tag="ON488_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231794.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            complement(2910..4820)
                     /gene="ltrA"
                     /locus_tag="ON488_001597"
     CDS             complement(2910..4820)
                     /gene="ltrA"
                     /locus_tag="ON488_001597"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCR3231795.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(5604..6809)
                     /locus_tag="ON488_001598"
     CDS             complement(5604..6809)
                     /locus_tag="ON488_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCR3231796.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(6832..6985)
                     /locus_tag="ON488_001599"
                     /pseudo
     CDS             complement(6832..6985)
                     /locus_tag="ON488_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(6988..8373)
                     /locus_tag="ON488_001600"
     CDS             complement(6988..8373)
                     /locus_tag="ON488_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HCR3231797.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(8402..8788)
                     /locus_tag="ON488_001601"
     CDS             complement(8402..8788)
                     /locus_tag="ON488_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231798.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(8804..9118)
                     /locus_tag="ON488_001602"
     CDS             complement(8804..9118)
                     /locus_tag="ON488_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231799.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(9471..9950)
                     /gene="rlmH"
                     /locus_tag="ON488_001603"
     CDS             complement(9471..9950)
                     /gene="rlmH"
                     /locus_tag="ON488_001603"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HCR3231800.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            10378..11667
                     /locus_tag="ON488_001604"
     CDS             10378..11667
                     /locus_tag="ON488_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HCR3231801.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(11706..12311)
                     /locus_tag="ON488_001605"
     CDS             complement(11706..12311)
                     /locus_tag="ON488_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HCR3231802.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(12507..12971)
                     /locus_tag="ON488_001606"
     CDS             complement(12507..12971)
                     /locus_tag="ON488_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCR3231803.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(12993..13313)
                     /locus_tag="ON488_001607"
     CDS             complement(12993..13313)
                     /locus_tag="ON488_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HCR3231804.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(13456..14535)
                     /gene="pepA"
                     /locus_tag="ON488_001608"
     CDS             complement(13456..14535)
                     /gene="pepA"
                     /locus_tag="ON488_001608"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HCR3231805.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            14735..15085
                     /locus_tag="ON488_001609"
     CDS             14735..15085
                     /locus_tag="ON488_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HCR3231806.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            15270..16223
                     /locus_tag="ON488_001610"
     CDS             15270..16223
                     /locus_tag="ON488_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR3231807.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            16236..18023
                     /locus_tag="ON488_001611"
     CDS             16236..18023
                     /locus_tag="ON488_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231808.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            18010..19212
                     /locus_tag="ON488_001612"
     CDS             18010..19212
                     /locus_tag="ON488_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231809.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         5456 a         3849 c         3469 g         6500 t
ORIGIN      
        1 gcttttgggt ctacaatcac tgcttgtgcc ccataaagca ctgcataata gacgataagg
       61 ttattcgcaa aggatttacc accacccagc gaaccgacaa aggcagacgc taacgcattg
      121 gttactgaac ccttaacccc ttgactggca agagcaggtt tcagatagac attgcgtcca
      181 gtatctaagc tgtagccaac ataaatcccc tcattttcac ccagcatttg agtagcacca
      241 aaacctaaac cagcgaggaa atcagaggtc acgtattgaa tatagtcatt catatatctt
      301 ttgctggcag gtaaaaattc ttcatgtaag cccagcatat ccccaaaagg tcgtaccagt
      361 ttcacgctca aatcatcata gaaatctttc acttcattac aacgacgttt aagttcgtca
      421 aggtcatttg ctgataccct tacaacatag gacagcttat acatagattc cttgctttgg
      481 tctaaattgg tttccagctc gttcacactt tccagagctt ccgccacatt agagctggtt
      541 tcattatcac tttgccaagc gtggttatcc aagtctttca gttctttctt tttattgcgg
      601 acagtagata gggctttacg attcgctaca atttccacat tcattgacgt atcaatcgga
      661 aaggtaaatt gctgttgctg gtagtagaag atttcagagg acgggaagtc cagttcgccg
      721 acaatactgt tgatggtaaa gtaagctaca taggcggttt cgtcttcctg ctggattttc
      781 aaatatcgct gtttttcttc caccagacag cgagtaggct taatgaggtc ataggtttta
      841 atcagtgttt catgttccag ctttttcttt gatagaggat actcatactc ttcataggca
      901 gtgcctgtct gtccgtaaag gtgttcaatc agatagccga agtcatcctt atctaatctt
      961 cggattttga aacgacggga gattttattt tctaaaagct tttccatctt ctgaaaacgc
     1021 aggatttcat cattactcat actaacaaaa tcgcccatca gcttatggtt cacatcatag
     1081 acaaaatcag taaaagcatt ttttgcttca acggtaagac ttttcataga aaactcctga
     1141 tcgttgagaa gcaacttaaa accgataaag aaacggtagt ccacttgatt ttcgccaatc
     1201 atggatatta aagcgtctgt ctgttggtcg attttgtcat aggcaaccgt tttgagcttt
     1261 ccagtgactt catttttgga acgttcttgt gcagaaagta tgctggattc tgtactgatt
     1321 tgtaaagcat gaatcttgcc atcacgattt tgtgcgataa gctgtctgaa agaatcatgt
     1381 acttgtattt tctgttccgg acttagaaat gagtaattgt agggaacaag ctcatagtaa
     1441 gcgtaacatt ccccatcttt attccagacc agattgtttt caatatattt aattggatat
     1501 gccataaaat tcactcctaa ctgctgtaat ggcttcttgt ggctggtttc tgccaagcgt
     1561 tacttttttt cctgcatagg tcagctttcg tcgcagtgca taagcaatga cagacttcaa
     1621 aaatccataa ggctttttac catcaaaggt ttttgtagac ataaaccatg tgaaagccac
     1681 aggaatccca aagtatttga gaaatgctcc ctctatcata gaaagagggg gcaagttgcc
     1741 aagtatcata actgcaaaga gtgacacgac aaaccatgtc atttgcgtaa aggttatggg
     1801 aaacggaagt ctaaagtcat tgatggagta caacactttc tcaacagacc agatactggt
     1861 atagcttcgt attttcttca tgtaatcaat cctttcataa aaatggggat agtcttttga
     1921 ctaccccgta aacaagaaaa tctgccagta agaatgtacc gacagattta atagacgatt
     1981 tcaaaaatcc cgtgattggt tgagataaac gttcccgaaa ggtctaaatc ccgaccatag
     2041 gattcataat caatatagtt ttgaagactg gctggcactt cgcctaaagc acccgtttct
     2101 tcaatgtagt agcgtgccac gtcagacata tcatcacaat cggaatgaat gataatatct
     2161 tcttgatgtt cgcttagttc ttcaatactt gaaaaatgag tgagcagagc agatagctcc
     2221 gattgtagtt cttctggcaa ctccgatacc atttcccata ggcgattgag ttcgctaata
     2281 gaagtgtatt cgtcaaccgt aaagggtaac tcgtaatcat gaatggcgta ttcctcatat
     2341 tcatcattca agccgatttt ctctttgact tcctcaaagt caatgggaaa ggtaaaccac
     2401 gcaccgacca attcgccctc attgtatttg cctaaattcg caatatagac ttgcatatcg
     2461 tccatatatt cacgtccttt ctttgtagag attcaaaaat ccctaccgca cttcgtttgg
     2521 tgtaccattc ctttgcggaa cataagaaaa ccacttatat tccacaaaag aacggtttta
     2581 tttaagcacc aataatgcga ttgaatagct ctagtaaaat gtcttttact ccagcagcgt
     2641 tgaagactaa gccaaccgca ataatcgcaa taattaaaaa gccaatcagt ttgctaaact
     2701 cacgcttgaa gccaagatac aagccaatca caacgattgc taaaagcacc agtgattgag
     2761 cgtttgatag aaaccagtta tatatggata ggtaagttcc tgatattata aatatctcaa
     2821 acttttcccc ccattcacac ggagcgtgcg actttcaccg cactccgcgt tccatcgtgt
     2881 ttatattgaa aagtatttat gtagtagacc tatatcaagt ttaattcttg attgccagct
     2941 aatactctat atttatttag tcttatgagc tggactttat ttagcttcaa tagagctata
     3001 tatttttgta ttgtttcttc tgttttagcg tgtattagac ggtgtaccgc ctcttttacc
     3061 aaaataagat ttttataatc gtcatttcca ccagctccag ttggtacaat atgatgacaa
     3121 tgtatttcat tagcttgttg aaattcttcc agagttatag cacattttcc atgttgagca
     3181 gaaaatagcg aaattcgatt gtctgcgtat tctattgtgc gattttccaa agataatttc
     3241 attaactggt acatcagtaa tttatcaaca cttagattgg tgtggataaa ttttcttccc
     3301 tctagagtgt agcaattcgc taaatacacc tttgccattg gttttctgtg ttggatatat
     3361 ccaacaggga aaataggttc gccctcgcca gcaacatacc gaagcatttt agatttacca
     3421 tatcttgttg cctcctttgt cgtaagttgt ctgcctgttt ttctcaatct gccccttttg
     3481 tttgtaccta atctgttagt gaagatagcc attacagctc tattcagttt catacaatcc
     3541 agatttacat tcgttgcaat ctgataataa ttttgcatac ctaataccat tgaattataa
     3601 agtcttgttt cttctaattc cgttttccct tttgagggag aagcaatttt ctttgcctgt
     3661 gataccagct tgtctttttg gtttttgaat tgtttatcac ttatatgtga tttaacaact
     3721 aacttctttc ttctcggtat cattttaatc ttgaaaccaa gaaagtcgga gtatcttttt
     3781 ctaacattta caattcttgt tttttcttgt gatacttcca attttaatcg ttgttcaatc
     3841 cattgagtga ttgctatttt ggctttttca gcactttcct tgtagcggca gaaaactcta
     3901 aaatcatctg cataacgaac catatacatt tcctttaact ttgttttctt catttctttg
     3961 taagcgttgc ttttacatgg gctaccgctt ttattgatat gaaccacata gttttttgta
     4021 acaggatttt cctgccattg gctttctacc caatggtcta actcattaag aacaatgttt
     4081 gctagtagtg gggatattat tcccccttgc ggagttcctt tctctggata tgttattgta
     4141 ccgttagtca ttttgattgg agcttttaat atccttttta aaatgaatat caagtgcttg
     4201 tcccgtattc ccatagccca tatctgtttt atcagcttgg aatggttcac gttgtcaaag
     4261 aaacccttaa tatcaaattc aatcacataa tgtagctggc tgatttgtag gcggttatag
     4321 gttgctttta ttgcattttc aactgaccta ttaggtctaa aaccatagct gttttcacta
     4381 aatttagctt cgcagattgg ttctaatact tgttttatac attgttgtat aagcctgtcc
     4441 cacatacaag gaatacctag aggtctggtt ttaccatttg gttttggtat ttcttttcgc
     4501 ctcactggct taggtcgata cccatgtgga ctgcctgcaa caatgtatct tacttttttg
     4561 acaactgttt ctgctggcaa tttgccaata tctttaatta ttgtaccgtc tgttcctgct
     4621 gttttactgc ctgcatttgc tttgatattt cgatatgcca gtaatatatt ttctctcgat
     4681 aggataatat ccataagatg agtgaaaata tctccattct tacttttggc atataaatca
     4741 tcaaaggtgt tttgcatttc gtaatattca gcgtgtctta aatcttctac acacaatgtt
     4801 tcatttttat ttttaggcat aaggcttcac tcctttactt gaaattgagt gagctttttt
     4861 atcttactcg taatccttat tgaaacaaca taatactttt ctaatatata cacgacttga
     4921 gggcattcct ccattctcat tacaagaatt tcttaggttc gccctctgct tttcagcatt
     4981 agttcaactg cttattgttc ttcgtcagtt tattctcttg atgagaaccc aatacctttc
     5041 ctcgttccga taatcttatc tatacatata tatccttagg tcactagcta taagcctgct
     5101 ggcttgatac cgcctgtaac gttatatggc atttcataac ctatattctt actttgccac
     5161 accagctacg atttctcgta cctttgcatt tctacaaagt tcaaatttag acccgtacat
     5221 tcgctgtttc gtcagttcct tatagaacat tctaaccata gatattttat agacccccga
     5281 cctgttggat acgctaccca cctctggata gttttcgata gaagatatat gttcatcaac
     5341 tattacggta tctttcagcc gtctttaccg agcttcaaac attctgagtt tcctcataca
     5401 atgcttgtcg gaggctcagg gcaggcgttt cagagcgtta cttcatcatt ccacctgtca
     5461 gattatcagt tctcctaata accaaacttt ttcgttcttt tattagtgcc ttagcttttc
     5521 actaaggaac gagtcgcaca aaggttttgt ccaaaattca taaaaatgtt ctcctctcta
     5581 tattcaatga atttgtattt gagttatttt tttgttgtta tcacgtcctg ttcttttact
     5641 gactgttgct tcaaaatctg cttgtgtcgg tctgtcagtt tcgcatggtc gagaatgtct
     5701 tttacaacct gcgtctggtt gatttcatca agtttaatcg caacctttaa ggtcggggca
     5761 acttgatgag atagccagtt cagcgtcctt tggaaggagt aaggctctgg ttttgtggtt
     5821 agttttaatc gttcacgatt gttcccaata aaccaagccc attcttcatt cagtttccaa
     5881 tcagaacgag gtttggaatc gtctttatct acaaaacgga tataccgatt gataatttta
     5941 aaggcggtat gctctggatt gtcatagacg agtaaatcac ggactgcata ataggcacgc
     6001 tcatttttca atcgaatctc aaaacggttt tttacttctg cgtcttcaat gggaatatca
     6061 tttttcttgt actgctcgta gtccttttca tagatacaga aataaacttc actttgtaat
     6121 gaaccgatat agagggtgtt tcccatacat tccttttcct ctttgcgtac cagttcgcca
     6181 ctgcgatagc ttttaaaact gcggaagacg gagatacatt cttcctgttg gcacttttca
     6241 gtgagtacag ggatatttaa aatccctgtc ttatcgttaa tggcaaggtc aaggcgtttc
     6301 atcacaccgc cagccaccaa aacgtccata aagaactcat accagcttct ttgttgtgcc
     6361 agaagatagc tttcaaattg tctgcaccca cgacctttca attccaccag aactcctttg
     6421 tccagttcat gggagcaaag gacgaatatg tcgcctaaag cataatgctc tgaataagaa
     6481 tagaaaccat agtcctcatg aagaaaatag gacagtttca gttgtaagat gttttcgacc
     6541 acctgctgta cgtctgttgt cggaaagcga attcttacat aatcaaacag catttcaagg
     6601 ggagcgtcgg gattgaagcg ttccagagct tcccaaaggg actgctgtaa atcctctgat
     6661 ggcttgactt ttcctgtttc aatatcgctt agatactgcc ttgtaatacc agtcgcaaca
     6721 gctaaacggt tttgagatag tccataagcc aagcgttttt cttttaaatg ctgtaaccaa
     6781 gtttgttcat tcagtaaaaa tccctccaat caaaaaggcg tatgtcaact tttaaagccc
     6841 atttgacata cgctgaaatt ttgtaaatcc cttgtaacca aaggattttc taatgttttt
     6901 ttgactgttt cctgtcgatt tgtacccccc tgttagatac cgaggggtta agtgctggcg
     6961 tggctattgc cacaccagcc agcaagatca gtccacacct gcgacttccg cttcgcacgt
     7021 cgcctgcgtg gactgtctgc tgttggataa ctttttaatt tcctccaaga aatcatatcc
     7081 ttttggtaca aggggagtat aaaactctga tatgacactt gttcctacat caacatagcc
     7141 acgacctttg attcgcttta agaagaaatc cttttgtacg tcactgccaa acatcatgcc
     7201 atagcccatt tcagacatac gacctaaagc cactctgaaa ttaaactgat cacggattcc
     7261 gtcgcctaaa tattttgcgt ctggacgttg acaagccagt attagaaaga agccagcttg
     7321 acgacctaac atgacaatct gtttcagctt attcataact gcggtgtttt cttttgttcc
     7381 cagcatttcc atgaaagcga cgtattcatc aaagattaag aagtgtgccg ggagacctaa
     7441 gtaagcataa tttttgccag tcttatagtt cttcatctgc ttcatttcct cactacgttt
     7501 catcatttct tcatagaatg tttcaatgca agaaagcaag tcttcttttc tatagtagac
     7561 atttgccatc acagaaccta agtccgcaag gtcagcattt ttcgggtcaa gaatatacag
     7621 ttttgaatct gtatgaagca aggcttcaat cagtgtcagt ataaagtaag ttttaccgcc
     7681 acctgtacca ccagcaatca acatatgagg gagcttatca tattcccacc atacgttttt
     7741 cattaagcga agtttaccat ctttagcttc tacttcatca atagaaatac gactggctat
     7801 ggtgtcatag agcaaagtat attccacata ggaatccttt aactctttat ccgtcagctc
     7861 acagtacaag ccactctcta atttcttttc caagtgtaag agttggtctt gatattttcc
     7921 cagcgtgatt tccacccgta tctgtatcaa gccattttta agtcgataat acattttagg
     7981 gaagtaggtt atcttttcct ttgtacgacc agcactatct ttaaagaaac cctctgtttt
     8041 gacctgttca gattcatacc acttgttttc aagtatcatc tttgccagtt tttgacggtg
     8101 gtaaagttgt ttaaccgtat catagcgaac ccgtttgaat acaaacgcta ccagcaagca
     8161 gataagaatt gcgacactga aactgataat taaataggga atgtcaatct tatctgcttg
     8221 tgataggtta aaatcctgcc agttgatctg ctggattgtc ttcacatgaa acagtccgac
     8281 aaccagcagg aaaacaggca ggagtgacgc tatcgtaaaa tgaaagacta aatctttacc
     8341 agatgggcga atccttttac cacgctgttt catgcgaaaa agtctccttt ctacctagcg
     8401 actatttgtc ttgtgtcggt tctttctttg cttgtggttg agctttgaat gaactagaat
     8461 cctttgtcag cacaatatcg tctgccttga tataccagtc aacatctgct ccttgatagg
     8521 tggcagtagc aacggtgtcc gcaatgggat tgataagttc cacccgtgcg ttataatcaa
     8581 actctttcaa aggcacgctg gcaggaatac ttacttgaat catgcgtcct tgtcctttgg
     8641 attttaagtc ataggtacgt tccttgattt catctgaaac cgacccgtct tcattttgga
     8701 ttctcacttc acgacgtaga gcagagaatt tcaattctcc aaaagtcgtg tctttatcta
     8761 atacaatgcc atttgctaat ctcatcattt ttcctctctt tctttattct tttatcatgt
     8821 cgtcagcatg taaaaggtaa tttgtaaaac cacgagtgcc gattttgtag ccctctgcgg
     8881 taatacgtgg attgactaac ttcacacgtt cctcaaagcc gaaatgtttt tcgccagctt
     8941 cagcaggaag caccaccaca atatcatctg ctctttgaac atcagaatag agattatagc
     9001 ttcttgataa gacagttagc cgtccgttga ttcttcgctg aacgacttta tcctcgccag
     9061 caaattctaa attgccgaat gttttttcca tgttgggaat cacaaattta agttccatat
     9121 ttttacctat cctttctttt ttattggctg aatgaatgtt tgatggtctt aaagagtggg
     9181 gaacgacctt ttgattcttg attttttgtt ttcataagtt cacttccttt caaaatcggg
     9241 tgaaaaaata gacacctcat tttttgaagt gtctacctat taaatattca aattttattg
     9301 gaagtatctt tatatcttca cttttcaagg ataaatcgtc gtatcaaagc tcattcataa
     9361 gtagtaaatt agtagtaaat tgagtggttt tgaccttgat aaagtgtgat aagtccagtt
     9421 tttatgcgga taactagatt tttatgctat ttttctctta aaaaatatca ttatttgtgg
     9481 tatggagccc ccgcgttgat ccggaaggca cggtagattt gctcgacgag gatcaggcgc
     9541 atcaattgat gtggatacgt cattttgcca aaagagatct gagcattgct tcttttcatg
     9601 acggcttcgc tgagtcctaa agaaccgccg ataacaaaaa caaggtggct ttttccttgg
     9661 atacctaatt ggtcgatttg tttagcaaaa gattcgcttg tgggattttt cccttcaatt
     9721 gctaagccat agacgtattc ttgttctttg attttcgcta agatccgttc tccttctttt
     9781 tcttttactt gtctcatttg cgcttcgctt aaattctccg gggctttttc gtcaggaact
     9841 tcgatcaatt cgattttcgc ataggcattc agccgtttga catactcatt gataccttgg
     9901 atcaagtatt tttcttttaa ttttcctact gaaataattt tgatattcat gttttctctc
     9961 ctttgatctt cacgctcact ttgtttatta taatcaattt tttcgtctat atgtttattt
    10021 tgactatttt tgttaaaaag atttccccaa cagttatgca caacatccac aggtttatcc
    10081 acagaaaaca gcgttgtttt accttatttc atcacattca ttaggcaaac atacgtttta
    10141 taagaattta tccactttat acacaggctg tggatatgtt ttatccctta tttttccaat
    10201 cctatccgcg tagttttaca caatatctgt ggaaaaagaa aatcaaatat tttcatctga
    10261 aaacaatgat ttttcctaaa gtttttcata aaaagttcaa agtctcaaag tagactaaag
    10321 tcaacaaata agactatact aacagtagat aaatgaatgt aattggagga ggaacacatg
    10381 gatagaaaaa atgtgacacc aaagatgaaa aaaaataaaa ataatagcct ctggcgtaag
    10441 ttgggtctgg ggcttgttgg agggatcgtt ggaggactac tgacagctgg cattttttat
    10501 gcagcgatgg gcactggcaa caatagttct actgctacaa gcggcaatca aaattctgcc
    10561 ggtgaaacag ttgtggaaaa tgtcaaagtc aatgtagatt ctgatatcac caaagcggta
    10621 gataaagttc aagacgctgt cgtttctgtt atcaacttac aaagtcaaaa ccaatcaagc
    10681 ggttttggcg gattattcgg gcagcaagaa gaaagtagca gctcagatga tagtaatttg
    10741 gaagcttata gtgaaggaag cggcgtaatc tacaaaaaag acgggaatac tgcttatgta
    10801 gtcacaaaca atcacgtagt agatggacag caaggtttgg aagtcatgat gaaagacggt
    10861 acgaaggtaa aagctgaatt agttggaaca gatgcctatt cagatttagc ggtgttgaag
    10921 atcaattcag acaaagtcga aacggttgcc tcttttgggg actcaagtgc tttgaaggtt
    10981 ggtgaacctg cgattgcgat tggttcccca ttaggatctg aatatgcgaa ttctgtcact
    11041 tcaggaatca tttcttcctt gaaccgacaa gtaacaagta cgaatgaatc gaacgaaaca
    11101 gtcaatatca atgcgatcca aacagatgca gcgatcaacc cgggaaattc tggtggtcct
    11161 ttagtgaata tcgaaggaca agttatcggt atcaactcaa gtaagatcgc aagtacttct
    11221 gaatcgactt ctaatgtaag cgtagaagga atgggatttg ccatcccaag taacgatgta
    11281 gtgaatatca tcaaccaact ggaaaaagac ggaaaagtga cacgtccagc tctaggtatc
    11341 acaatggtcg acttatctgc cgtttctact cagcaacaag aacaaatctt gaagattcct
    11401 tcatctgtaa ctaacggtgt catcgtgaca aatgtccaaa cagctacacc ggcagaaaaa
    11461 gctgggttga aacaatacga cgtcattact aagatcgatg acaaagaagt ttcttctggt
    11521 gtagaacttc aatctgcttt gtataagaaa aaagtgggag attctgtcaa aatcacttac
    11581 tatgaaggct cgaaagaaaa aacaactact gttgaattga cgatcgatca atcggcatta
    11641 aaacaaaatc aaaatagtga aaattaataa aaaagaggtt gtgacaaaga cttgtcacaa
    11701 cctctttatt ttggaaatac ttctccgact acggcatcct caggcaatac taagattcct
    11761 tttttttctg gagcatttgg caaatgcaat tcacgagcag aacaaatcat tccatagctg
    11821 gctacccctc gcaaagttcc tggccagatc atcattccat ctggcatcat ggctcctggt
    11881 tttgcaacga caactttttg tccagcttcg atatttggtg caccgcaaac aatttgcaat
    11941 actgtcccat tgtccacttc tgtctcagta atcgataaat ggtcagagtc aggatgcggg
    12001 acgcatgttt ttacataccc gacaacgatc ttcggttcat gatcagcttc aagctgttct
    12061 tcgaatcctg cttctttaat caatcgattc aatttcgcta attcttcatc tgttaagctt
    12121 acttggccgt tcccttcaat tgttagatga tcggagatat ggaaaaagtt ccaagcaaca
    12181 acttgacctt gttcatcttt gatccgagca acattccatt tacgttcgac agtgttttct
    12241 gttcctttat cgtcggctat gataaccatc aaagtgtctc cgacgtgtgc tttgttataa
    12301 gcaaaaatca tgttctttcc tccattatcc tttgctgaga tttatcttaa caaaaaattg
    12361 cattcactgc atgagatttt tttcatgctt tatttccgaa gaagcttctt ctggaacacc
    12421 atttattcgt aacaagggac tgtgacaaga cttttgtcac agtcccttta ctgtttgatt
    12481 aaaaaggtta tacaagttcc acttgcttaa ttactcggct gttcttcttc gtcagaaacg
    12541 atcaagacat cacaaggtga atgacgtatg acgtagctgg ctacacttcc tgtcataaag
    12601 cgttcgactg catttagtcc agactgccca accatgatta gatcgattgc atattttttt
    12661 ggcaatttga ctgccatgga ttcacgaaca gagccgtatg caataattcc ttctatattt
    12721 gtgtaatcaa cagattttcc atattcttta cattcttcga tcatttgctt ggctgtttca
    12781 gtttgctgat cgactagatt ttgatcaata ggagcatagc ccataaaatt ataaaattgc
    12841 tgatcgatta cgtttgctac atatactttc ccattattac ggcgagccac ttctaacgct
    12901 tttttgaaag cagcaagtgc ttgttcacta ccgtcaatac ctactaaaat gttcttatat
    12961 tcttgattca tcttgacccc tcctaacaga tgtcagcctt ttattacact ttctaggaac
    13021 gattcgattt cctgttttgt tttacgatct ttattcacta gacgacctaa ttcttttccg
    13081 tcttggatca cgacaaaact tgggatacca aaaatgttcc attcagcggc tacatctatg
    13141 tacttgtcac ggtctacttc aataaattgc caatcagaaa agtcattttc gatttcaggc
    13201 atttgcggtt tgataaaacg gcagtctccg caccagccgg cagtaaagaa aaatacactt
    13261 tttccagttt ctacgtagcc tgctaattct tctaaactat ttgggataat cattcttttt
    13321 cctctacttt ctgtttatgt atttttcaat taaattatac acctttcttt cgaactaaca
    13381 aacattgatc ctctttttat aaaaaaaatc tgacaaaagg ttgcttttgc cagattttat
    13441 agtttcacta tcgcgttatt tcccgtatac gatcgtgttc actgttgatt tatctaaacc
    13501 tttcaatgtt tgaatcaaca tttctcgtgc agcttcaaaa tcgcgaatac tgaacatcgt
    13561 ttgatgcgta tggatataac gtcccactac gccaatcact gtacttggga ttccttcatt
    13621 ttgtgtatga gcagcacctg catctgtacc gccttttgaa acaaagtatt gataagggat
    13681 gttgtttgtt tcagcgatat ctagcaagta ctcacgcaaa cgaggaagca tgatcaaacc
    13741 tggatcttgg atacgcatca atgtaccttc tcctaaatgt ccgaatgtgc catttttcgt
    13801 cactgtgtca tctgctgcag agcagtctac tgcaaagaac agatctggct tgaatttatt
    13861 gacagaagct ttagaaccac gcaagcctac ttcttcttgg acattcgcgc ctgcaatcaa
    13921 tgtatgacct aatgtttcat tttgtaacgc ttctaaagct tctaatacca ttgtacagcc
    13981 atagcggttg tcccacgatt tgctgatgat attcttcccg ttggctgttt tgatcgtttc
    14041 agcgtaagga acgattgtgt ctcctggaag aacaccgtaa ctcattgcct cttctcttga
    14101 ttcaaaccca gcatcgaaca aaatatctgt tacttctact gatttttgtc cgcttgttcc
    14161 tcgtaataaa tgtgggggaa cggaagaaga aatacatgga taattcttac cagtagaggt
    14221 tttaagtgta aaacgttgag cagaaacaac gtaagggttc catccgccta gaggtacgac
    14281 tttaaaaagc ccgttttctt ggatttgtgt cagcatgaat ccgacttcat ccatatgtgc
    14341 tgcgaccatt acacgaggtg catccgcttc ttcatggtgg cgcagcccaa aaatgccgcc
    14401 caaaccatct aactgtaact catctaccag cggttccata tgactttcca tataggcgcg
    14461 aacgtcttgt tcaaaaccgc ttgttccttg taattctgtt aactctttga ttcgttgaaa
    14521 tgttttttct tccatatgct attcgtctaa atttcagact aaactcctct cagacttata
    14581 ttgatctgcg gataaaatat gattttttct gcagaccgat cgtatttatt atagcttatt
    14641 ttttctggta gcggttattt atttcaaaga aaatatgaga gtgtggtaaa ataaacacaa
    14701 agagtagcaa gtgagaagaa ggaggtatat ccacatgtat gaagaaagcg aattaagcta
    14761 ttttaaaggc gggttagccg ttgggatcgg tctaggatta ttgagtgggg tagcttcaac
    14821 gatttggtat catcgcaaaa aagtgttatc agcagaccaa gtgcttgaaa atatcaaaac
    14881 atctttttta aaagaaggcg caatcgaagg tgcttggatc tcttttgaaa aagaacctat
    14941 tcggaaattc gccgttcggt cgagtgctta tcggggtggg ctttcccgga tagaagatgg
    15001 cgaaactgtt tattatgaat ttttagcaga tgctcataca ggaaccgtat tagacatttc
    15061 aagaaaaaag ggcgcaatag attaatacgt caaaaaaatg aaataacgaa tacgcaccca
    15121 ctatctaaaa gagaggtatc ctatccttct tttatagtgg gtgattttta taaaaatagg
    15181 gctatttcct cttggaatag ctagtatttg tagttattat acggtattct tgaaataaga
    15241 ttagttttat tatataagga gagtgacaaa tggaatcacg tgaaaaaatt gccgtgctca
    15301 ttccttgtta taacgaagag gcgacaattt caactgttat tgaagatttt aaaagggaat
    15361 taccagaagc agatatttat gtctatgata ataattcgac cgatcgaaca tacgaattgg
    15421 ccgttcaagg cggagcaatc gtaaagaaag aaccacgtca aggaaaaggg aatgtaatcc
    15481 gtcaaatgtt ttttgatatt gatgccgatt attatttgat ggtagatggt gatgatactt
    15541 atcctgcaga agctgcacat ggtttgcttg agaaattacg ttctggcgaa gcagatatgg
    15601 tcattggcga tcgtctatca aatggaacct attttgatga aaataagcgt cctttccatg
    15661 attttgggaa taatctggtt aaaaatacaa ttacttactt atataaaaca aaaattcgcg
    15721 atgtcatgac cggctatcga ggattcaatc gaatttttgt caaaagcttc cctattatga
    15781 gttctggttt tcaaatcgaa acagaattga cgattcatgc tttagataaa aaattcaagt
    15841 tcgttgagat tccaatcgat tatcgcgatc gtcctgaagg tagcgaatca aaattgaata
    15901 cattctctga cggattcaaa gtgatcatga tgatcatcaa aatgtgcaaa gattataaac
    15961 ctttgctttt ctttgggatc tggaccatct tcttcttttt atttggattg gtcatgggga
    16021 ttcctgtgat tcgtgaatat atgctgacaa gctttattac acgcatccct tctgcgattt
    16081 taagtactgg attgatgact ttagcccttc tttcattagt aacagggttg attttggata
    16141 cggtcgtcac aaatgccaag aaagaatatg aattgaattt ataccatgtc taccacgaat
    16201 atcaaaataa agaaatgaag taggaggcct tttttatgca taagaaaaag gagaatctat
    16261 ttcctacttt ttttgcaact ttatttgcgt caggttttgc tttttttact tcttatggtc
    16321 taggaacttt gaatccaaca gtaatcattg gtttagccat ggttttgcta cttgctttta
    16381 agcaatatgg aatagagttg ttttcaataa aaaacaaagt tgcagctatt gcccgattgt
    16441 ttttttctgc agcttttgct cttacacttt ctattggcag acagatacaa tttcagtatg
    16501 tctcagcaaa ctatacaaag acaacgattg ctgatggaag tattttttac tttcttgttt
    16561 atttctccat ttttgtgtat tcttttttat ttttacaatc gatttattta tcaatgccaa
    16621 aactggaaac attttttact gctcaaaaca cacaggcttt ctcttcaaga aaatattttt
    16681 tattctttac tgtcttttta gttctgtgtt ggcttcctta tctgttggca ttgtatcctg
    16741 gagtggtttt gcctgattcg ttaagttcgg tcgcccaatc tatgggtgat gttcctataa
    16801 gcaatcatca tccagtctta ttcaccttac tggtcaagct atttgttcat gatttaccaa
    16861 ctgatacgat caatcacggt gtatttttat tttcgatttt tcaaacattg ataacagctt
    16921 cagcgataag ttattctctt tgctggctgt taaaaagaaa catccatttt tttccggtac
    16981 tcattagttt atgctatttt gcatttgcac cggtttttcc aatctacgcc ttgaacatgc
    17041 aaaaagatac tttgttctct atcgcttgct ttttattttc cttagcggtt tttgacttta
    17101 tttttcaacg agaaaagcca acgattctca atcagattta cgtaatcatc cttgctttac
    17161 tgaccaccta tctaagaaat aatgggattt atgtagtaac cggcacaggt ttgatttgcg
    17221 gcttgattat tttgaaacaa aaaaggtatc aagcattctt tcaagtggtg ctgggttata
    17281 cagtgattgc tggactactc atccacccgt tgatggctcg ttatgctatt cctacagaaa
    17341 ctgctgaaca attaggtgtt cctttgcagc aaatttctag aactattgtt atggatggtg
    17401 acttgtctaa gaaagataaa gcattcatga atcagctact cccgataaaa gattatgaag
    17461 cgtattctcc tagtcttgca gactcaatca agtggcataa aaattttaac aatgagtttt
    17521 tgaatacaca taaaaaagaa tttctatcac tatgggcaag aaatttacca agtaatataa
    17581 aaatctatac agatgcttat attttagaaa cgttcgggtt ctgggtacct ggtacaaaaa
    17641 atagttacgg ctttttagat actcgtgtaa acacgaataa ttatggtatg aagcaagtag
    17701 atttgattga acatcttact ggattgtcag gaatgaaaaa aatcatcgat gctcgtgatt
    17761 tctttggttc cggcacatta ctgtggttag ctatcggcag tgcactttta gcaatcttta
    17821 agaaaaaata tcggtattta ctcctttttc ttcccggtat gcttgttttt gctactatta
    17881 tgattgctac tcctgtggct tttagtttac ggtatgtgtt tgttttagca ttaggtctac
    17941 ctgtttatat cctctctcct tttttactag ataaaagaga aaaaatgaaa acagatatag
    18001 gagatactca tgaaactatt taaaaagata ttttttgctt ttgttctctt gatcgctagc
    18061 tattgcgtac tactgacaat tacttttttc attccgcagc actctattga atcgaatgca
    18121 gaaaaatctc tacagatggt tgaaaaagaa ggaatgtatc cttctatcaa tcaaggaaat
    18181 atgctaggca ctcggttaga taattttact gatcatttga tgatacgaaa aacaaaagca
    18241 gatcctgaat tgaactcctt ggagaacgcg atgtctatgg cggattatcc ccgttattgg
    18301 catggttatc agcttttttt acgaccttta ctgctaggga tgagtttggg gagtattcga
    18361 atgatttacg cagccattct ttttctgctg attggattga cgagctactt tttaaccaag
    18421 tgtagcgaca tctatttaac gacagccttg ttgatttcgc ttgctatagg aaatgctgca
    18481 acctttttct tcagtatgca attttcaaat atttggattt tgactttatt gtctgtatta
    18541 ctatttttaa caaaaccaca actctccaac accaaccaac aattattctt gtatttcttt
    18601 gtcattggtt ctttagctaa cttttttgac ttgttgacaa caccggtcat ctcttggggg
    18661 atacctgtga tcattattta ttatgtaaca aataagtatt taatggataa acgcagttca
    18721 ttgagcaaac aagtaggcag ttttgttttt accggtatct tttggggatt aggctatggt
    18781 ttgacatggg tggctaaatg gatcctatca tcgatcatat tgaacaaaaa cattgtaaaa
    18841 gatgcaatca accaaatcct ctttcgaacg gaaggaaacg acaaataccc gttgcatcga
    18901 ttagagatgc tgaaaagcaa tattagattg atgtatccaa aagtagcaat attattgcta
    18961 ttgattactt gtcttgtttt tctctatttt gcttatcgta aacgaaatag ctggcgtccg
    19021 ttccaacttc tagttttgtt tgttttagct gctgtaacgc cgtatatttg gtacaatatt
    19081 ttagctaatc actcacagat tcattattgg tttacgtatc gtacgcaaat catcacaagt
    19141 tttgctatac ttagtgcttt cgcctttttg atccctcctg agaaatcaaa agacgaacta
    19201 aattactttt aagaataccg atgtactaat tcatttttaa acataaaaac tccagctgtc
    19261 agagatagcc ggag
//
LOCUS       DAJSMK010000045        19253 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.047, whole genome shotgun sequence.
ACCESSION   DAJSMK010000045 DAJSMK010000000
VERSION     DAJSMK010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.047"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            912..2162
                     /locus_tag="ON488_001613"
     CDS             912..2162
                     /locus_tag="ON488_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HCR3231810.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            2181..3191
                     /locus_tag="ON488_001614"
                     /pseudo
     CDS             2181..3191
                     /locus_tag="ON488_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
     gene            3201..3854
                     /locus_tag="ON488_001615"
     CDS             3201..3854
                     /locus_tag="ON488_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR3231811.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            3873..4871
                     /locus_tag="ON488_001616"
     CDS             3873..4871
                     /locus_tag="ON488_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCR3231812.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWKPTVSLEEGLRESYNWIEKQIKG"
     gene            4947..5708
                     /locus_tag="ON488_001617"
     CDS             4947..5708
                     /locus_tag="ON488_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HCR3231813.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            5726..6832
                     /locus_tag="ON488_001618"
     CDS             5726..6832
                     /locus_tag="ON488_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCR3231814.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRDVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            6822..7055
                     /locus_tag="ON488_001619"
     CDS             6822..7055
                     /locus_tag="ON488_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231815.1"
                     /translation="MINDMEVTKLMALRNRYALNIVDNCTRKIAKILGCCIGKGAQIG
                     NSVEFVHNSVGTVIHSDTILEDGVKVYQNVTCG"
     gene            7254..7709
                     /locus_tag="ON488_001620"
     CDS             7254..7709
                     /locus_tag="ON488_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HCR3231816.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            7723..8496
                     /locus_tag="ON488_001621"
     CDS             7723..8496
                     /locus_tag="ON488_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR3231817.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            8483..9613
                     /locus_tag="ON488_001622"
     CDS             8483..9613
                     /locus_tag="ON488_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCR3231818.1"
                     /translation="MIGYKVSIMKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRD
                     VPPLDPKIKSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYE
                     GGLYVLCKRHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAE
                     FPELNAKSYVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMD
                     VRKKVHFTIAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAI
                     FPYKEIYGSGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKY
                     VNLSPAEKSKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            9644..10879
                     /locus_tag="ON488_001623"
     CDS             9644..10879
                     /locus_tag="ON488_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231819.1"
                     /translation="MQISKWKIIQFLMVFLMIISSSILKPLGGWLGETMNVRLVTVIL
                     AIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAYIYSDKTIWVKSRESMSLYYVLLAY
                     PLFCTLINQAWNLDSMLNTICGVTFLSYILRTSISLIQKFSGVLLYENIYRECAPENW
                     YRGGFLRINPPCFTIIIIPIALYMIERQVVARRKVKYYLLIASALAYSAVIHGSRSVL
                     VYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVIFINSTMFSTFVETFTNSTGEYAGS
                     AESRFASVWFFVPKFLQSPLFGTGILTGEEFTFILPGGVRGHLSDIGFFYTITQYGVG
                     ILIFDILFIIKGFKTALLASKVGMTGYQYLAFGITLSVLLTGINIDWFYPIFTPAIPV
                     CLAVIEYIYQECRSVANIE"
     gene            10904..12013
                     /locus_tag="ON488_001624"
     CDS             10904..12013
                     /locus_tag="ON488_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231820.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAKYEKYMDFVWEE"
     gene            12055..13389
                     /gene="gmhB"
                     /locus_tag="ON488_001625"
     CDS             12055..13389
                     /gene="gmhB"
                     /locus_tag="ON488_001625"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HCR3231821.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            13424..15061
                     /locus_tag="ON488_001626"
     CDS             13424..15061
                     /locus_tag="ON488_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HCR3231822.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            15163..15558
                     /locus_tag="ON488_001627"
     CDS             15163..15558
                     /locus_tag="ON488_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HCR3231823.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            15576..16307
                     /locus_tag="ON488_001628"
     CDS             15576..16307
                     /locus_tag="ON488_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR3231824.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            16331..17782
                     /locus_tag="ON488_001629"
     CDS             16331..17782
                     /locus_tag="ON488_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCR3231825.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            17808..18419
                     /locus_tag="ON488_001630"
     CDS             17808..18419
                     /locus_tag="ON488_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCR3231826.1"
                     /translation="MIDIISAIMVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            18601..19116
                     /locus_tag="ON488_001631"
     CDS             18601..19116
                     /locus_tag="ON488_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HCR3231827.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNGERLSF"
BASE COUNT         6204 a         2686 c         4209 g         6154 t
ORIGIN      
        1 atatatatgt atatggtgac tgaagacaaa aaaacagaac taatgaaact gaataaaaat
       61 atagagtgaa ctagtttcta agagggattt taaactagat ttcattggta ataaaatttg
      121 gagagatgga aaaacagcac ttaaggaagc agattttgtt gtcatttttg ttcctacaaa
      181 ctatggtagt gaatgtgtta ttgaattagt gatgtctgtt atttcagagg cattggggat
      241 aattaaatcc actatacctg taggatatac aaaaagtgga agaaaaaaat attatcaata
      301 gattttattt agttcagaat ttttacgtga aagtagatta ttaatgataa tctttatcca
      361 attagaatta ttatcgtagg atgtgatgat gaaagccgtg aaattgttca agtatttacc
      421 aatgtctccc tgccagtaaa tccgcttaga atttgagcct tgaaaatgtg caatgataaa
      481 aaacaaaaac tcgctcaaaa tagacagttt ggggtgggaa tagaccaata atgtaccaga
      541 caaacttcca tttggggtga aaataggtca ataaagcgat gttaaacata cctttggagt
      601 aagaatagag ggtaataagt gaatttataa actttttggt gactggttga gtggaaaatg
      661 taggtacatt tcaatgcgaa aatgtattat aaccccaaac gaggtcaata aaaatgactc
      721 aaacttgcaa tataacccta aacgggtagg ggatttatga aaaattgaat ttgccggcgt
      781 aggagctggc tgttttaagt atgaatgaac acagctttcg ggctgtttta tataaatagc
      841 aggttactgt tcacaaacag cattttgtta agaaagtagt gaccacagca gtggtggaaa
      901 gaggaaatat tatgaagaaa cagtataaca ttgcagtcgc cggcaccggt tatgttggtt
      961 tgagtattgc cactctgttg gcacagcacc ataaggttac agcggtggat atcattccag
     1021 agaaggttga actgattaat aaccgtaaat ctccaatcca ggatgattat attgaaaagt
     1081 acctggctga gaaagaactg aatctgaccg caacattgga tgcaaaggca gcataccagt
     1141 ctgcggattt tgttgttatt gcggctccta ctaactacaa tagccgcact caacattttg
     1201 acacatccgc tgttgaggct gttattaggc tggtcatgga agtaaatcct gatgccatta
     1261 tggttattaa gtccaccatt cctgttggat acaccgcttc tgttcgtgta aagactggta
     1321 gcaagaatat tattttcagc cctgagttcc tgcgtgaaag taaggcactg tatgacaatc
     1381 tgtatccttc gcgtattatt gtgggtaccg atatggatga tgagcgtttg gttgaggatg
     1441 cacacacttt tgctacactg ctacaggaag gcgcaatcaa agagaatgtg gacacattgt
     1501 tcatgggctt tactgaagca gaagctgtta agctgtttgc caatacatat ctggctcttc
     1561 gtgtcagcta cttcaatgag ctggacactt atgcagagat gaaaggcttg aacactcagc
     1621 agatcattaa tggagtttgc cttgatcctc gtattggtac tcattacaac aacccttcct
     1681 ttggttacgg tggctattgc ctgccgaagg ataccaagca gcttctggcc aactacgcag
     1741 atgttcctga aaatctgatc gaggcaatcg ttgaatctaa ccgtactcgt aaggacttta
     1801 ttgcggatcg tgtacttcag atggctggtt attacaatta cgcagaagca aatcagtatg
     1861 atgctggcaa agaaaagcct gttgtgattg gtgtttaccg tttgaccatg aaatccaatt
     1921 ctgataactt ccgccagagt tctatccagg gcgttatgaa gcgtgtaaaa gctaaaggtg
     1981 caactgttgt gatttatgag ccgaccttga aagatggaga gactttcttt ggcagtaagg
     2041 ttgtgaatga tttggaacag tttaaggcaa tgtgtgattc tgttatagca aatcgctacg
     2101 atgcttgcct tgatgacatt aaggaaaaag tatatacccg tgatatcttc cagagagact
     2161 aagattagga gagagtattt atgattatta caaaaacacc gtttcgtatg tctttttttg
     2221 gcggtggaac ggatatggag gattatttca aagagaatgg cggtgcagtt ctttctacta
     2281 cttttgataa gtactgttat gtgaatgtga gacatctgcc tagatttttt gattacagcg
     2341 ctgagttatc ttattctcgt actgagagag taactagcat tgaagatatt gagcatcctg
     2401 cgattcgtaa tgcgatgaaa atgctcgatg tgcatgaaat tcggcttaca tacgaagctg
     2461 atttacctgc tcgctctggt ctgggtacat ccagttcttt tgcagttggt atgttgaatg
     2521 ctttttatgc actggagggt aagtatgctg acaagaagaa acttgctgat gaagccattt
     2581 atcttgaaag agttctgtgt aatgaagccg gtggatggca ggatcagatt gccgcatctt
     2641 atggtgggtt caatcgaatt aatttcaatg tggatggtta tgaggtgctg cctgtcatta
     2701 tttcgcctga acgtaaaaag cagcttaaca acaatctgat gatgttcttt accggattca
     2761 ctagattttc ttctgatgtt caaaaggcta acaacgtcag tggcacagag gataagagag
     2821 taagactgaa aaagatgtat gagcttgtag atgaagctga ggcaattctt actgataaga
     2881 acagaaattt agatgatttc ggtagacagc ttgatgttac ttggagattg aaaaaaggta
     2941 ctggtggagc aattagtaca ggaagcattg atgaactata tgaaaagggt atggctgcag
     3001 gtgctttagg cggaaagttg ctcggtgcag gtggtggagg tttcttggtt ttctatgtac
     3061 aacctgagaa ataggatgca gttcgttggg ctatgcgtga tttgatgtat attccgtttg
     3121 aatttgaaga tggtggaact agagttattc actacacgcc ggaaacttat attgaaaaac
     3181 agaatggata aggagtaaca atgttagcgg aaaaacttaa taaacatatt gacttattga
     3241 ttaaacgata tcctacactt gagacgatta aacaggacat tatcgatgga tacctaatta
     3301 tggaggaatg ctatttgaat ggtggtaaac ttcttgtggc aggaaacgga ggatcagccg
     3361 ctgactcgga acatattgct ggcgagttga tgaagcggtt taagacgcca cgtcctgtaa
     3421 gtaaggaatt tgccgataag ttagttgcaa ttgaccctgt aagaggtccg gaattagcca
     3481 aaaatctcga gtgtggttta acggcaattc ctttggtcgc acacgaagca ttgtctactg
     3541 cttatattaa tgatgtcgat ggtttgggtg tcttcgcaca gcagctgttt ggctttggta
     3601 gatctggtga cgtattcctt ggtatttcga cgtccggaaa tagcaagaat attatgagcg
     3661 caactgttgt tgctagggct ctcggtataa aagttattgg cttgacgggc gcaaagggtg
     3721 gggaacttgc cacggtagca gatgtttgtg ttaaggctcc tgaagttgaa acatacatga
     3781 ttcaagagta tcacttgccg atatatcatt gttggtgttt gatgctggaa gataaattct
     3841 ttggaaacga ataaaatttg gaggaatgtt aaatgaaaaa gacaattatg gttaccggtg
     3901 gttgcggtat gattggctcc aatcttgtta agagactggt gaaggaaggc tgctgggatg
     3961 tttatgtagc tgataatctg tggagaggaa agttggagta cctgaacgac gaagatgggc
     4021 atcctgtcat cgacctggat actcatttct tcaatgctga tctgactgat tatgagcagg
     4081 ctaaaaaggt tattggtacg actgagtatg tagttcatct ggctgatgtt gtggctggca
     4141 ttgactatgt gtttaagaac cagggcgaat tgttccgaat caataatctg atcaattcta
     4201 atgtttttga ttgttgccgt aaggctggca aggagaaaat caagggtgtt atctatgttg
     4261 gtaccgtatg ctccttccct ctgaccagac agaatacttt gaatcctgag cctctccggg
     4321 aagaggagtt gttccctgct cttcctgagt ctgcttatgg ctggagcaaa ctgatgggcc
     4381 agttggagat ggggtatttg gaaaaagaaa ccggaattcc gtgctgtatc ctgatgcttc
     4441 ataatgttta tggcacacct actgattttg gcgaacgtag tcaggttatt cctgctctga
     4501 ttcgtaaagc aatcaataat cctgaagagc cttttaatgt gtggggtagc ggagagcagg
     4561 gacgtgcttt cattcatgtc aatgatatcg taaatgcatt ggtgctcgcc ctggataagg
     4621 gttggggtca tggtcatatt cagattggcc cttctcactg tacttccatc aaggaaattg
     4681 catataagat cattgaaatt tctggcaaag acatcaagcc tttctttgat acttctaagc
     4741 ctgaaggtga taaggctcgt tgcgcagatt attctaaggc gaaagagatt ttggattgga
     4801 agcctactgt ttctttggaa gagggtcttc gtgaatccta caattggatt gaaaagcaga
     4861 ttaagggtta ataagtatat aagctgttct tcctccgtgt aattagagga tgcggaggaa
     4921 gaacatatga gtaaggatgt actgagatgg aaaagaatat gtataaaaga aaacgtgatt
     4981 tcactgtgtg tggaatagta ggtgtttgtg ctactacaaa gaacgagttt gtaagggaag
     5041 ttttttccat gccaacatct ccggtaagtg cgactgttga tctcgtggga gtgccggcca
     5101 ttatttcggc aaaggaaaat cccaaaattg ctgagatgta tagccaggct acaatggctg
     5161 caatagatgg tatgcctatt gttaaaattg gacggcgcaa aggatttacc tgtgaacgat
     5221 gtgctgcacc agatattatg ggaatggttt ttgaagaagg cgttagacag ggaaaaacac
     5281 attatttcta tggtggaaaa gataacgaag tgttaaataa gcttcgtgca aacctagaaa
     5341 gagattaccc gggaatcaaa attgttggaa tgtattcccc accatttcgt ccgttaaatg
     5401 aagaagagga tagcaagatt tgcgaggaaa tcaacaactt aaatccagat tttctgtggg
     5461 ttggtattgg tgcgcctaag caagaaatgt ggatgtggga acaccagaag aagatccata
     5521 acacagtaat gttcggtgta ggcgccggct ttaacttttt tgcgggcact ttggaaaaag
     5581 ctcctgaatg gatggaaaaa gctagtctag agtggttatt tagactggta aaggaacctc
     5641 gtagactatg gaggcggtat atcttgggag gtataaagta tatctactat actattgaat
     5701 ctaagtaggg gggcaataaa aatagatgaa aatacttata gtagttacaa tgacgaataa
     5761 ctttggtaag aaggggtcct ataattctca ggaaatagga ttagctcgag ggttagctga
     5821 attaggccac gaagttattg tatataaaag tgtaaaaagt gatgaggaag ttggaacaga
     5881 gcaattaagc aatacggcga tgattcacta tatcaagtgt cgttatgtag gatcaaatgg
     5941 attcttatca acaaagaatt ttgataagaa tgcggatgtt ctaatacaat ttgcggacct
     6001 tcaactatca gtacctcatg tatactcatg gactgtaaaa aatggaataa aatatatacc
     6061 ttataatggg ataacgcgaa gtcaaagtgg caataaatat ataaagacaa ttattgaaat
     6121 attggcgcat cgaaattata aaatttataa gaaaaatggg tgtgttgcca aaaatgatcg
     6181 agtttctgaa aaattagtac aattaggagt aaataaagtg aaacttgctc ctgtttgtgt
     6241 ggattttgaa cagttacata agaattacga agcaatagat tttactactc tcagagaaaa
     6301 atggaatatt cctcgcgatg ttcgtgttat tttatatgta ggacggtttg aaaaggataa
     6361 aagaccgtta gatatgatta gtttatttaa taaacttgat gagcataatt atttgctgat
     6421 ggtaggaact ggtgctttac tcgagcaaac gaagcagcag ataaatttac ttggactgca
     6481 gaatagagta aaaataattg agcgtattcc taacaaagat atttgggagt tatattgctt
     6541 atcggatgta tttgtaaatc taaactatac tgaaatttgg ggtatggttt tgctagaggc
     6601 aatgtactat cgcctcggaa ttattgctgt taatgcacct ggcccacaga atattatttt
     6661 ggataataga tatggaatgt tggctaaatc tgacgatgaa attttgacat tcttaaaaga
     6721 cggacgattt accaacgata tcatagatgc agcatatcag cgtgtaacta cagaatttag
     6781 atggtcaaag tcgggagaaa ttatgcttag catgttggaa ggtgataaat gatatggaag
     6841 taacgaaatt aatggcattg aggaatcgat atgctttaaa catagttgat aattgcacga
     6901 gaaaaatagc caaaattctt ggttgttgta ttggtaaagg tgcacagata gggaactctg
     6961 ttgaatttgt tcataattct gtaggcactg tgattcattc tgacacaatc cttgaagatg
     7021 gtgttaaagt ttatcagaat gtgacgtgtg gttgagcaga tagtaatgaa cgtatcatca
     7081 ttcgagtaaa aaagaacgct gttttatgtg tgggtgctaa aattctttgt aaatctaaca
     7141 cagaattatg cgttggggaa ggtgctgtag ttgctgcaaa tacagtggta ttgaggtcta
     7201 ttccacccta cgaagtgtgg ggggtacctg ctaaaaagat ggggagataa aacatgaatg
     7261 catataaatt atacaaagta gaacgatggt tttacttaca caaaatggag ttttttgcca
     7321 agattgtaaa ggcactaatt tatgtacttc ataatagctc aatttcatat caaacagaaa
     7381 ttggagataa ttgtaagttc ttatacggtg gcataggttg tgtaattgga aaagatacaa
     7441 aaataggtaa tcacgttata atcggaacga atgtactgac tggtggtaga tccaataagc
     7501 ctggtatgcc tacaattgga aacaatgtat atatcgctac tggcgcaaaa attttaggta
     7561 atatcacaat aggggacaat gtaatagtag gggctaatgc tgtggtcatt aatgatgttg
     7621 aacctaattg ttcggtagga ggcgttccgg ctagagtatt gaaaaaagat attgatgtaa
     7681 atgattattg tagtttgaat cgttactaaa aggagagatt gtatgttgta ttttgttatt
     7741 cctttaatga gtgcgaaggc agcaaacaat tgggagatgg ttagtacctt atttaaccga
     7801 acattatggt cgtgttataa tcagactgat cctgatttca aaatcattgt tgcttgccat
     7861 gaaattccta aactcacgca tgaatatgat gacagagttg aatttattca agttagcgaa
     7921 aaggatgccc ctattcccac aaatcaagac gaaaaaatga ttgataaggg ttataaaaca
     7981 catgctctcg caatgcgttt gcgagagttg ggcggcggtt tcgctatgat ggttgacgca
     8041 gatgatcttg taagttctca tttggcggaa tatgtgaatt cccatcccca ggaaaatgga
     8101 ttttatgtca aaacgggata cgtgtacttt gttggagacg attatatgaa ggttctacca
     8161 aagttctcat caggaagtgc gtgtatagta aaatatgcag tggaagacct gcctgaggca
     8221 tatccggaag ttatgacagc aaattgtgat gataatccat ggatcattag aaaacgacat
     8281 gggggcgttg ttccagcatg tgaagagcaa gggcgtccat taaaacctct tccattcaaa
     8341 gcagcagtat atgtattagg aacaggggac aatcactcgc tttatggtaa aacgacaaaa
     8401 tatcagacga agatgcgaga gatactggaa atgtttatag caaaacgtaa aattaaagga
     8461 aaactgaaag cagaattttc tgttgattgg ttataaggtg agtattatga aggtattgat
     8521 gtgtgaaagc caaatgccag agaattggta ttcgtttgat ctttctaaag aacttaatca
     8581 atatgttgat ttaacattgc tgtgtaagcg tgatgttcct cctttagatc ctaaaattaa
     8641 gagcaaacat attttgtatc ataaaagtac aaataaagtg ttttcggcac ttgtttttct
     8701 gaaaagcttg ttcttaattt ggaaggaaat aagatttggt gattatgata ttgttcattt
     8761 gcaattgatg aaaagtctca aatatgaagg cggattgtac gttttatgta agagacacta
     8821 taaaaaatta attatgacag ttcataatgt gttaccacat gaggttcgtg aaaaggatcg
     8881 ccaagagcac tttaatatat attcaaattg tgatggtttc attgttcaca atcgagtaac
     8941 agaacagcat ttatatgctg aattcccaga attaaatgca aagtcatatg tttgtccaca
     9001 tgctatctat ggagatgtta aacatatatc tagagcgtat gataaagata agtttgaatt
     9061 tatcttgttt ggacaaattc gtccatataa gggaattgat gtactgctta atgcaatcac
     9121 agaacttcca atggatgtaa gaaagaaagt tcattttacc atagcaggtc aacaacatcc
     9181 taaacaggat agtactgact ataaaaaaat gattgaagat ttaaaggttt cagattgtgt
     9241 tctatataag ccagagagaa tttctgatga agaaatggac agtatgttca gaaatgcaga
     9301 tgccgcaata tttccatata aagaaatcta tggaagtgga gcgcttctta tggcatacac
     9361 ttattgctta ccaactattg ttagtaatgt acctgctttt atggaagaaa ccgaggaagg
     9421 aaagataggg ttacttttcg aaaatttgaa ttctaagagc ctagcagaca caattgtaaa
     9481 gtatgtgaac cttagcccag ctgagaaaag caaaatagag gatgatatat atgagcttgt
     9541 aaaccgcaag tatacctggg cggcatctgc aaaactcaca tacgaggcat acaaacaaat
     9601 tttgaatgag tagtaaaaca attagaaagg aataataatt aacatgcaga ttagtaaatg
     9661 gaaaatcata cagtttctaa tggtctttct aatgattatc tcatcaagca tattgaagcc
     9721 tttgggcggc tggttgggag aaacgatgaa cgttagactt gtgacagtca ttctagcaat
     9781 agtatgtttg ttaatagcct cattaccagc atttagaaaa aatagatatt taaatttctg
     9841 cactttactg atttgtgttg ttataatagc agcttacatc tactcagata agacaatatg
     9901 ggttaaatct agggaaagta tgagtttata ctatgtatta ttggcgtatc cattgttctg
     9961 tactttaatt aaccaagcgt ggaatttgga ttcaatgcta aatacgatat gtggtgtaac
    10021 atttctttca tacattctta gaacatctat ttcacttatt cagaaatttt caggagtact
    10081 tctctatgaa aacatatatc gtgagtgtgc cccggaaaat tggtatcgtg gaggcttttt
    10141 aagaattaat ccaccatgtt ttacaattat aataataccg attgctttgt atatgattga
    10201 gcgacaagtt gtagctagaa gaaaagtaaa atattattta ctgattgcta gcgcactggc
    10261 atattctgct gttattcatg gttctagatc tgtccttgtc tatcaaatta ttgtacttgg
    10321 ttgctatatc ctttttaaga aaggttcttc gaaaagaaaa attgcaatgt gggttttagc
    10381 tgggttgctt gtagtcatat ttattaattc gaccatgttc tcaacatttg ttgaaacttt
    10441 cacaaacagt acaggtgaat atgcaggatc tgctgaatct cgatttgctt cagtttggtt
    10501 ttttgttcct aaatttttgc aatcgccttt gttcggtact ggtattctta ctggtgagga
    10561 atttacgttt atattaccag gaggagttag aggacaccta tctgatattg gatttttcta
    10621 tacaattact caatatggtg taggtatact tatatttgat attctgttta ttataaaagg
    10681 gttcaaaaca gcattacttg catcaaaagt gggtatgact ggctatcaat atttagcatt
    10741 tggaattaca ttaagtgttt tgctaacagg gattaatata gactggtttt atccgatatt
    10801 tactccagct attcctgtat gcttagcggt tatagaatac atctatcaag aatgtagaag
    10861 tgtggctaac atagaatagg aaatattaat aggagtgcat ctcatgaata agaaagagat
    10921 tttatataac atattgaaga agtacgaaaa tttaccatat gtgtttagga acatgtttgg
    10981 tcataatata agtaaactcg tatcttggaa attgactgct gattgtgcaa cagtagaaga
    11041 aaattctgaa gtttatgcag cgtttcaatt gcgctcaaag gacatgtctg atgttccagt
    11101 gatgggttta gttaattgtt gcaaagatgt agcaattgta atgcaggggc cactatgttt
    11161 aaaggatgat ttctcttata atactctggc ctactataag aaatgttatc caaatgcttt
    11221 aattattctt tcgacatgga aggacgaaga tattaaggca ttgaaaagga tagaggatct
    11281 tggagttata gttatttgta gtgagaaacc tgaaaagcct ggacacttaa atattaatta
    11341 tcaagttgga aacactttgc ctggaatagt cagagcaaag cagcttggtg caaagtatgt
    11401 ttgtaaaact agaacagatc aaagaatata ccatccaaat gcaatggcgt ttttctgcag
    11461 tttacttgaa cagtatcctg ttaataacga agatgattgg aaattaatac aaaatcagcg
    11521 attactgtta ctatcaatgc cgtatggaga catgtttttc ccgtattgtt tgtcagactt
    11581 cctgtatttt ggtgatgttg atgatatgat aaacctcttc tcgattccta gtgatgtgag
    11641 agaaaaggga gctgtgtcta gaggagtctc aagaagggag atatctgaaa ataatttagc
    11701 tccagaagtt cagcttcttc gaagctatat ttcacgaatg gggggcaatg aggagtgctc
    11761 tattagggca tattgggagt ttgtaaaaaa ccatgttatt actattaaca aaaatcaaat
    11821 tgatttgtac tggcataaat atgtaggtcg ttattcaaat aatactattt atggtacgta
    11881 ttatattgat gatagccaag atgcacttca ctgctataat tttgatttta taaattggtt
    11941 gaatttgtac actggaaaat acgaatacaa agcaaaatat gaaaaatata tggactttgt
    12001 ttgggaagag taattaactt ttatagtaaa aagtacttta gggaagggca tattatgaaa
    12061 acagtaatta tggcgggcgg acgaggaagc cgaatttcgg aattgtttcc ggatattcct
    12121 aagccaatga ttcctataga tggcattcca gttttagaac gagaattgtg ttcgcttaga
    12181 gatcaaggct ttaatgatat tattttgact gtttcctatt tgcatgaaaa aatagaggag
    12241 catttcggag atggttcaaa attaggaatt aaaatcaaat attttattga aaaaactcca
    12301 cttggcaatg caggtgcatt gtattttttg ttggatgaac tgggtgatga accgttttta
    12361 cttttgaatg ctgatgcagt atttgatgtt gatttcaggc agatgattag atttcatgtt
    12421 gagaataacg cagatgttac tttgtttacg catcctaact cacatccgta tgatagtgga
    12481 ttaattatat ccgatgacaa taagaaagtg cttcaatggt tagcgaagga agatcaaaga
    12541 cctgaatatt ataaaaaccg agtaaatgca ggtcttcatg ttataaatcc gaaggtgttg
    12601 agagaaaatc cattaatgga aattgtaaat aaatcaatag ttgaaggtgg ggggctacca
    12661 tacaaaattg atttagatag aatgattctg aaaccattgg ctaacacagg gcgtatgtat
    12721 tgctacgatt ctccagagta tgttaaagat atgggaacac cggaccgata tagagctgta
    12781 attaaggact ttcaaaaggg aattattgtt ggtaaaaatc tatccaatcc acaaaaagca
    12841 atctttttag atagagatgg aacgattaat aaatacgttg gttttttgag aaatgcagaa
    12901 gaatttgagt taattgatgg agtatcggag gcaattaaga ttattaattc tctaggtttt
    12961 ctgtgtattg ttataacaaa tcagcctgta attgcaagag gtgaagttac tgttgatgag
    13021 cttaatagta ttcacaataa gcttgaaaca atgctagggc atgctggtgg atttttaaac
    13081 ggtatttatt actgtccgca ccatccccat aaaggatatg caggagaggt tatagaatta
    13141 aaaattgatt gcaattgtcg caagccaaaa cctggactgt tattagaagc atcaaaggat
    13201 tttaacataa acctaagtca atcatttatg gttggagata gtgaaagtga tgtaattgct
    13261 ggaaaaaatg ctggttgtaa gacagtactg attacagaag acatcacctt gcctgctaat
    13321 tatggccaag actatagtgt ctgttcattg ttagaatttg ttaaaaatca tttatgcact
    13381 atgcaataat tggtttagtg aaacttgtaa aaggagtaat tagatgaagg tattaattcc
    13441 agcagcaaaa gttgttgaaa aagaattgca gagtatagga atgttaccag caattatcta
    13501 tccaattaat aaaaaaattg tctttgatta tttgtataat cagtataatg caatctgcga
    13561 ttcattggat attatctgtt atgaaaaagc ggataaggtt catagaagac tgaaaaacta
    13621 tcatgattcc agaattcata tatgtgacct tcctgaatta ggggatctag ggcaaaccgt
    13681 gtattttggg ttatcagatg aagatgagcc tgttctaatt aacttcgcag atacaattgt
    13741 tatggagagt atgtctgata tagaaatgga tacattctat tattctgaag attttgtgtc
    13801 gagtacttgg acatacttta aaattaatga aggaataatt actgatatcc acgataaaga
    13861 ggaagcttac gtatccgata aacgtgaaaa attatttatt ggcgtattta tgttttcttc
    13921 gtcaaaactt ctgaagagtt gcttaagaga ggcagttgag agtcggaaac aggggggaat
    13981 aaactcattt tatcgggctt tacagctata cagcgaacgt tgtccgctaa aggccgtaag
    14041 aacagaaaag tggtttgata ttggacacat cgataaatat tacaatacaa agttggaagt
    14101 taaagcacga gagtttaatc atatctctat agataaagat cgagggatat tgaagaaaac
    14161 tagcgatgac aaggataaat ttattggaga aataaagtgg tatttaaaac ttcctgctga
    14221 tattgaatat gtaagaccta gaatttttga ttattctaca tcttacgtag ctccctatgt
    14281 tgatatggaa tattatgcat atcatacggt tcatgagtta tacttatatg gtgatttaaa
    14341 atataaccag tggcatgatc tgtttagccg tataaagttt atctgtagcg attttaagcg
    14401 atacacctta aaagatgaaa agattagaga gtcattggaa gatatgtatt tgcgaaaaac
    14461 catgcagaga tttcaaaaat tgtctgaaga taaaagattt tcagcttttt ttgagaaaca
    14521 aattcaaatt aatggtcgta agtttatttc tttaaccggt gtaattgaac ttctaaagaa
    14581 tcttatccca agtatgctct atgatgtaaa tgaattttgt attatacatg gagatttgtg
    14641 ttttgctaat atgatggtag attccaattg ttcctttgtt aaggttattg atcctagggg
    14701 aaaatttgga aaatatgata tttatgggga cagcagatat gaattagcaa aactatttca
    14761 tagtttagat ggtaaatatg attatatcat caaggatcta tttactgtag aatatgatac
    14821 cgagtgtgca gtgatagatt atacaattaa tacgcgtgta agagattacg atttatttga
    14881 attgtttaag tcggtctttt cggacgagat taaggacgat tttgataaga ttgtattgat
    14941 agaagcgttg ctatttctta gtatgattcc attacacggt gaaagttttg atcaccaaat
    15001 agtgatgctt gctacaggta tggaacttct tgcaagagta agtaataaag ttatactcta
    15061 atataaattg tgccttaatg aataacggtt acaatactgt tttagcaatg taggcattaa
    15121 ggcacgatta tattaattaa tacaatagaa gggaagagaa aaatgtatag tgaatattct
    15181 tttgtgtttg atatcgatgg cactttgtgt ccgataaaga agaaggatga gcgatatgag
    15241 gatttggtgc cgtatgagaa tatggttgaa aaactgagat tctataagga gaatggtgct
    15301 aaaattacat tgttcacctc acgcaatgtt aattcctata aaggaaattt gggaatgata
    15361 aatgctaata ctgcaaaagt gctcttggcg tggttggata aatgggacat tccgtatgat
    15421 gaaatcctgt atggtaagcc ttggccgggg cataaaggct tctatgtaga tgatcgaacg
    15481 gttagacctg atgagttttt gagatgctct gtagatgaat taaatgaaat ctgcaacagt
    15541 tcaaaaaaaa gattctaaat aaggaggtta gttctatgga aaaaaagatg acagttatca
    15601 ttacgatggc aggtttggga agtcgttttc gaaaaattgg ttatgcggtt cctaaatata
    15661 tgattaatgc caaaggaaga actttatttg attgggccat ggatagtttg gttggataca
    15721 ataaaaatgt tgataagtat atttttgttg ttcgtcagga agacaacgct tcagctttta
    15781 taaaggagca ttgtgcttac tttggtattg aaaacgtaga agtgattgaa atagactata
    15841 tgacagatgg tcaagcaact acatgtatgt tggctattcc ttattgcaat caagacaatg
    15901 agattatggt ttacaatatt gatacatacg tggaatcaaa tgagatgaaa tacgaagata
    15961 tttgtggaga tggacatatt ccatgctttc atgctgatgg cgatcattgg agttttgcaa
    16021 agcttaacga tcgaaatgaa gtaatagaag tccgcgaaaa agttcgcatt tctgataatt
    16081 gtactcttgg tgcgtattat ttctcatcgg caaagctgta taaagcttta tatgaagagt
    16141 attatgcaga ctcctctaat atggagaaga atgaaaaata tatagcacca ttatataact
    16201 ttatgataaa aaaagggtta aaggtgacta ttagcatagt agatgcgaaa aaggttcatg
    16261 tgcttggtac tccagaagag ctcaatgtgt ttttgaatca agaataaata gtgtttagga
    16321 gaaaatagca gtgaccagta ataatctaat tgtaaaaaca ttaagcagat ataagaatac
    16381 tccacttcct gttaaggctg cattatggtt tatggtatgt ggttttttac agagaggggt
    16441 ttcaatgatt acaaccccaa tttttactag agttttgtct acagaacaat acggtttata
    16501 cagcacttat ctatcgtggg aatccttatt gctcatgatt acatcgctta gtttgttcaa
    16561 agccatgatg aatctttatg taaaatatga taatcaagaa catattcttt cgacagtatc
    16621 cggattgact ttagtactga ctattttttg gtttgttatt gctattttta ttaaggatat
    16681 attggcagaa attttaggat tgacaccagt tctagttgtc tgtatgttct catattttat
    16741 atttcaggca gaaatacaat gttggtcttt acacaaacga tatatatatg attataagac
    16801 tttattagta gctacccttg cagttactgt tggctcatct gtagttggct gtttagcggt
    16861 tctgtttata tctcctaccg ctgaggcgag agccttaatg aatgtcctag tgactggtgt
    16921 tgttggcgtg gctgtgtata tatcggtatt tagaagatgt aaggatttta aggataatga
    16981 agtgtggaat ttcgcagtag tattttgtgt atcgttgatg ccacactatt tatctgaatt
    17041 tattctgaat ggttctgata aaattatgat aaattactta tgtggttcgt cagatgttgc
    17101 tatttacagc gtggcatatt ctattggtgc tctaattaac cttgttacaa attctgtcaa
    17161 ttccactttt gcaccttatc agtatcaaaa aatcaagtca ggagaatatg atttactatc
    17221 aaaaagagct aatgaagttc ttggtttggt agcggctatg ctttttgcat taatgctatt
    17281 tagtaaagaa attgtgttga tatttggtgg gcagaaatat atcgacagtg ttaatttaat
    17341 tgtacctata tgtatcggta tttatttcaa ctatatgttt cagctgtttg ctagagtaca
    17401 ggaatacttt gaaaagaaac tcactgtcgt tattccatcg gttttgtgtg caattatgaa
    17461 tattgtacta aattatgttt ttataaagtt atatgggtat caggcggtag catacacaac
    17521 tgtattctca tatatgtttt tctgcgtcat ccattatatt ttttatagaa aagtttgcaa
    17581 agaactattg gatggaaaaa acatatatga tgtcagagga atacttttga tttctgcaat
    17641 cacgatagct ggtggcatcc taatttcaat aattaataaa tttgatttca taaaatattt
    17701 aattatagca attgcttgtg tcgctgcaat tatatttaga aaacgattgc tacttttagt
    17761 aaggagaatt atgagcaaat aaacatttgc tcatagagag atagagaatg atagatatta
    17821 tttctgctat aatggtaaat gtattaacag cattatatca gccgttctta tttgccgtat
    17881 taacagcgta tctgtttatg tactggtatc tatttatagt tgataactct cgagatccta
    17941 aaaacttaaa agattctgta ttaatctggt tgagatattt taaagcatct agtaaatttc
    18001 gcagactctt ttttcttgcg ttttatttta ctttgatatt atttaaaacc ttgcttaatc
    18061 gaaatatgtg gatgaacccg ctttcaaacg ttattggaca gtggtcatta tatattatag
    18121 ataatgctac aggagagagc agattgacaa cagaatgcgt ggagaacacg atgctgttta
    18181 tccctttttg catgttattg ttatggtggc gtgacattaa atgtgatatt atacgcacca
    18241 tctatgttgg gattaagtat gtgtttttat tctcattaag tatagaattt acacaactgt
    18301 tttttaggct tggtacattt caactatcgg atttgtttta taacacccta gggggcttaa
    18361 ttggtgcttt gctatattgg ctattctacc gattaaataa gtatatagac ttaaaataga
    18421 actgctttga attttaatat ggttaatatt tttctgcaga caggattgtg taatctcatc
    18481 aagaatactt tacatgccat ctatttttgc taaaacattg ttgttatatc ttcaagaggt
    18541 agggaatttt attgctttaa atgaggtcga gcgaattaaa aaattggtaa aatatataac
    18601 atggtggtag ttatggtaaa agtgtttgat ataattaagt tttcggattt cagaggatat
    18661 actgctgttg cattggataa tgagactctt ttctcgattg gtattgagtt tcacattaag
    18721 caaataaatc aaggatttag tcataataaa tatactatgc gagggctaca ttatcagagt
    18781 ggagagcatg ctcaaggaaa gatagtgatg tgcctacatg gtgaaattat gaatatcgca
    18841 cttgatattc gacaaggatc ttccacttat ggatgtgtgt atgtcaacac attgagtgaa
    18901 agcaatggta aatgtgcgta tatcccacgt ggatatgctc atggctatct tactatggag
    18961 gacaatacgc tagttcagtg gtgcgtagat aatgatttca attctaatgc tgccaaatgt
    19021 ataagttatg aaagcgtaga tattgaatgg ccggtcagtc ggcagtgttt cgttataagt
    19081 gagaaagaca aaaatgggga aagattaagc ttttgattaa aatgagctgt ggagaaaaga
    19141 aggatactgg aaaataagaa gaacaataac cgagcaaatg ctcggttatt tctatgagga
    19201 atacataaaa ctaaatttag atatagatat ttattcacga aaaactaata ttg
//
LOCUS       DAJSMK010000046        18154 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.048, whole genome shotgun sequence.
ACCESSION   DAJSMK010000046 DAJSMK010000000
VERSION     DAJSMK010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18154
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.048"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(160..444)
                     /locus_tag="ON488_001632"
     CDS             complement(160..444)
                     /locus_tag="ON488_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231828.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(462..1352)
                     /locus_tag="ON488_001633"
     CDS             complement(462..1352)
                     /locus_tag="ON488_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HCR3231829.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1372..1590)
                     /locus_tag="ON488_001634"
     CDS             complement(1372..1590)
                     /locus_tag="ON488_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HCR3231830.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1560..3260)
                     /locus_tag="ON488_001635"
     CDS             complement(1560..3260)
                     /locus_tag="ON488_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HCR3231831.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3527..4300
                     /locus_tag="ON488_001636"
     CDS             3527..4300
                     /locus_tag="ON488_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231832.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4381..4950)
                     /gene="thiT"
                     /locus_tag="ON488_001637"
     CDS             complement(4381..4950)
                     /gene="thiT"
                     /locus_tag="ON488_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HCR3231833.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5016..5118)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5124..6095)
                     /locus_tag="ON488_001638"
     CDS             complement(5124..6095)
                     /locus_tag="ON488_001638"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HCR3231834.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6189..7562)
                     /gene="glmU"
                     /locus_tag="ON488_001639"
     CDS             complement(6189..7562)
                     /gene="glmU"
                     /locus_tag="ON488_001639"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HCR3231835.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8065..8883)
                     /gene="purR"
                     /locus_tag="ON488_001640"
     CDS             complement(8065..8883)
                     /gene="purR"
                     /locus_tag="ON488_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HCR3231836.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9050..9874)
                     /locus_tag="ON488_001641"
     CDS             complement(9050..9874)
                     /locus_tag="ON488_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCR3231837.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9847..10527)
                     /locus_tag="ON488_001642"
     CDS             complement(9847..10527)
                     /locus_tag="ON488_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HCR3231838.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10550..11488)
                     /locus_tag="ON488_001643"
     CDS             complement(10550..11488)
                     /locus_tag="ON488_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HCR3231839.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11733..12596)
                     /locus_tag="ON488_001644"
     CDS             complement(11733..12596)
                     /locus_tag="ON488_001644"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HCR3231840.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12738..15311)
                     /gene="mprF"
                     /locus_tag="ON488_001645"
     CDS             complement(12738..15311)
                     /gene="mprF"
                     /locus_tag="ON488_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCR3231841.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15452..16258
                     /gene="proC"
                     /locus_tag="ON488_001646"
     CDS             15452..16258
                     /gene="proC"
                     /locus_tag="ON488_001646"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HCR3231842.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16337..17893)
                     /gene="rny"
                     /locus_tag="ON488_001647"
     CDS             complement(16337..17893)
                     /gene="rny"
                     /locus_tag="ON488_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HCR3231843.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
BASE COUNT         5238 a         3910 c         3110 g         5896 t
ORIGIN      
        1 aataccgaga aaatggtttt tgaacatcac ttattcaaaa taaaaaaaga ttgtgacacg
       61 aattttgtca caacctttaa atgtattcct agagcaaaga agctaagcga agaaatccaa
      121 ttctgattat ttattgtatt tctttgttca gcatccttgc taaaagccca tattggacaa
      181 agtattcact acacccatga tctcatcttt tcgagaacgt gctttttctg tcggatcttc
      241 tacctcttct gtgtcaattc gaacaataaa tttccgattc atcgtcacgt aagcaccgtc
      301 gttgatcaaa ataaacagtt cgttctcatt atagtctgca caggcatctt tccatacgtc
      361 aaagccgttt ttttcagaag ggatatcccg tttaaccaca gtttttccac ttaattcgtg
      421 gaacgttacg tcataatatt tcattatctc tacctctttc gtcattcaat attttgtact
      481 tgttctctga ttttttctaa gatcgtctta gactggacga cttgattttt aatttcgatt
      541 gcatttgatt tggaaccgat cgtgttgatt tcccgattca tttcttggat caggaaatct
      601 aattcccgac ctacaggaca ttgtgcttcg ataagttcat ctagtttttg tacatggatc
      661 gccagacgat ccagttcctc gtgaatatct ccgcgttcca acaagatggc tagctccgtc
      721 aacaaccgtt gctcatcgac tttcgctcca agaaattcct ccagcttttt ttgatacctt
      781 atttgaaatt ccttttcata gatttctaca aaactatcga gtttttttag tacttctttg
      841 aattcttcag tattcttttt caacactaaa gctaaagctt gaccttcttt ttctcgactc
      901 gcctcaatag aatcaagtgc gcttttcaat gtatctagag ctaactgtgc caattcttcc
      961 atgctctctt ccggtttttc ttctaccgtt acgaagtttt cgtccagcgc gaagcgttcc
     1021 gccatccgac taattgacac ttgattttga ctaccgtatc gttgttgaat tccgtctgtc
     1081 aattgagtga taagtgaatc aatcaattcc cagttgatga cgatctgttt ttcgtttttg
     1141 ccaatataag ctagattcac aaatacttcg attcgaccgc ggcttaactg ctgtttaata
     1201 agctgacgaa aatcgttttc aacaaagttc aggattttag gacttcgtat ttgaacatct
     1261 agaaaacgct ggttgacact ttttatttca atatctaact gatacgcttt tgtttcgcgg
     1321 atggctttgc caaaaccagt catacttttc attcgacagg gtccttcctc attacatatt
     1381 ttctattgct ttttgcagtt gttcaaactc ttcgttcgtc aatgtcaggc ctttccccat
     1441 tttttcatgg tctggcgccc aatctcgaag atcgaatttt ggcgggcgac cattccagct
     1501 gactaggttc agttctttac gccacccctt gttgttttct gacaatatag cgatttcttc
     1561 tacgatttca tatgaaaatt cttgtgccat ggttgttcct ccttgagata atataaatat
     1621 aggatcagta atgtgtcaac tggttgctta agcaattcat gctgcaaacg atccttgcgt
     1681 tttccttgta gcagataatc aaaataaaca gttttcgtgc gctcattttg tattttttgc
     1741 tggtattttc gataccttcg ccattcttca gtacttaatt gaccaatttg tgccaataaa
     1801 tcatccggca tactttttat atcttgttgg cagatcattt gaatcatcat gtctacttga
     1861 tagatttcat tgggcagtaa aaaatgtttt tttgctaaaa gttctagcat cgccaatccg
     1921 catgtctctg gtacgaccct gttcttatat aaattacgca gtttttgcca aaattttatg
     1981 cttttgaaaa aagataattc taactgaatt tcttttgtta agtaagacaa aaatcctcgc
     2041 cagtatgttc ttgcaggttt aacagaatga aatgtatacc agttcccata gtaatagcct
     2101 aatcgttttt tcatttccag atagcctaat tgtaaattta attggttcct ttggctatca
     2161 aaaagcagaa agctgcctag tgtccacaat gtttgacatt tccaatggat aaaaatgtct
     2221 ggcatacgaa tttttttcgc tgggcctggc ccttgcacat ctacgacaaa tgcctctgtt
     2281 gctcctttgt taatcgcaat atcaataggt attttgttgc gatacccacc gtctgcatat
     2341 ttattttttc cgatctttcg ataagccata gcgggataaa atgaagcaga ggcgagtatc
     2401 caatctggta tttcttctgt ttttgtctgt tggatatcag tcactacttc cgctagttct
     2461 ggcagtttag tagacaccgt atataaacgt attttgggat tatgtttgag taaggacaaa
     2521 tccaaattgt ctttgaccat cttttccaat ggagcagaag aaaccccgcc ttcaattagt
     2581 gctgttttcg tcatttggcg tctttctcga tagaagcgtt cacgaaggtc ttcaactgca
     2641 gccatttctg gtaacgcaag cacttgtctt gtcgacagct ttttccataa attcacagct
     2701 tttttcatat ctccttgtaa aatcaatgcg ccgttcaacg cacctaccga ggtacctgtg
     2761 ataatctcaa agttgatatc atgttccttc agcgcctgcc acacaccaat ctgataagca
     2821 ccgtgcgctc ctcctccacc taaaacaagt gctgtatgat agaccagctt tttatttaat
     2881 tgtgtggttc cttgatagcc gtttttatga aaaatacgca accattcttc tgatagagga
     2941 gattgaaata aaaaacaaca gttttcttta ataaaaaaac gagcgcaagc ttccatatac
     3001 cgaaaaaatt ttttccattc aaaagtttca ccttcaatca acagattatt aaaaataaca
     3061 tctcctctac ttttagcaat agtaaaatag acggtatatt ttttcgatac tgctttaaaa
     3121 gcacattgct tttttgcaga acgccaaaaa gcgtctctac tttcttgatg actttgaaaa
     3181 aatggaaggg gttgttttgc ttgctggata ggcgaataca gcgacatttt ctgtgaaaag
     3241 taaacttttt ttatctccat cgcgctctcc tttttcttca agtataccag tacgtcataa
     3301 aaaggtcatg agtctcgtat tcgactttgt agattccata agaaaacaat tcataaaacc
     3361 tcctttaaat aaaaaaatac aaaaatcaca aaaattaatt gaaaatgaga gtgttttcaa
     3421 tgaaaacgtg attttgtaat ggaattttaa aataaaagaa acaagctttt ttaatgcaaa
     3481 tgttgtaaaa taaaagagat taagaggaaa taagaggagg aacatgatga ctgagtcagt
     3541 ttatgtacat attgatacca caagtaatgc tgttttaaca aaagggctga ctgctactga
     3601 ctttgcaaac agtatcgtgc attttcctca aaacttgctc ttgcttgatc catctgcttc
     3661 tgctggagaa tatgaatccc atacagggct gaaagtaatc cgtggtacag aaaatattca
     3721 gcgtttcttt tcctcttctc gtaacaggcg tggattcgat gaattgaagt ggatcgactt
     3781 tactgattta acgatgctga aagaattgac acctttagaa atttcagaat tattatattt
     3841 tggtcatatg aaaacacatc ttcattcgcc gtttttttat aaactacaga ataattttgt
     3901 atacttcgat cttaatgatc agctgaatcg gatttattat cgctatttag atgaatttta
     3961 taggattttt gctagtaaat taagttcgat cttgtcagat aagatcaatg taaaaaaatc
     4021 ttttttcaaa aaagaaacac ctgttgaaaa aatcagtgtg gaattattga aagaaatgcg
     4081 taatttgatg caggaaggga tcattttttc ttttgatcaa gttggtttga tcgatggtaa
     4141 atatcgtatc ccaatctatg tgattgaaga ttatatttgg aaattaaaag gcacccggta
     4201 tcgagaagag gaaatcatcg ctactttaat ctactctgtc accgatcgac actggcaatt
     4261 ggtagaagat gccgatcttt cttatctgcc attgaagtag atctatttct tatcaaaaaa
     4321 taaaaaggaa acaagaaact aggacatgat tctgtctcaa gtttcttgct tcttttttat
     4381 ttacagctcc tgtcgtttat ctggcacaaa aatcgaagga gtcgtttgtt ggatccctaa
     4441 taaaacgatg atcgttacaa tagctgtact caacccgctg gcaccattca ttacgaaaga
     4501 aaagagccaa ggattcatcc cccatagtgc atacgctccc cagaaaacca ctcctgcaat
     4561 aaaatgccaa aaatatctgg aaagtgcgcc aatcaatgca ccaaacacga tgctttttct
     4621 aatttgtttc gtattatcgt ctacatagcc tttttggaca tttgaagcca tgagccctgc
     4681 tgcgcctgca aaagtatagg caatcgggta ctcaatcaac acttgaacga cacttaaata
     4741 ataaacttgt cccaacggaa aatgtaggat gccccaaatg aaacctgcca gcatccctgc
     4801 ctttgtccct cttcttaacg caaaaagagt caatggaatc tgccctaatg aaatagaaaa
     4861 actgctgccg atctggatcg gaatcaacga caacaccatc gctaacgctg caacaatcgt
     4921 tccttctacc caaactctat tttttcccat aaaaaaactt cctcctttga ataaaaaagt
     4981 cacaaaggag gaagcagctt tcgaaaatag tcaaacagct gtttattcac aattcctacg
     5041 ctcgcataac cgatacaggt acgaagggtt tagaaataga ttcaatctca gcccaattgg
     5101 actccccttt gtgagtttat ttattattta ttttttgttt caaacaatgg actaactggt
     5161 ttgttttcat ggatacgttt gattgcatct cccattagtc cgccaacact tacttcatcg
     5221 attttgtcga ttttacgatc ttctggaaga tagatcgagt ctgtaacaac tagacgctcg
     5281 atagctgaat cttctattct ttgtaaagca gggccggata atactggatg tgtacatgaa
     5341 gcatacacac tagttgcacc agcttctttc aaagcattgg cagccaatgt gatcgtacct
     5401 gctgtatcga tcatatcatc gatcagtaca caagttttgc ctttgacttg tccaatgata
     5461 ttcattactt ctgcaacatt tgcttttgga cggcgtttgt ctatgatcgc aatcggagat
     5521 ttcaaaaatt ccgctaattt acgtgcccgt gtgacaccac catggtctgg tgaaacaacg
     5581 acaacatcat cgcctttgat tcctttttct aagaaataat tggcaataag tggcgcaccc
     5641 atcaaatgat cgactggaat atcaaagaaa ccttggattt gaactgcatg aaggtccaaa
     5701 gtcagcattc ttgttgcacc agctttttga atcatgtttg ctactaattt cgctgtgatt
     5761 ggttcccgtg cacgtgcttt acggtcttga cgcgcatagc cataataagg catgactacg
     5821 ttgattgttt ttgcacttgc tcgtttcagt gcgtcaatca tgatcagcaa ctccatcaag
     5881 ttatcattga ctgggctgct cgttgattga ataacataga catgcgatcc acgaatactt
     5941 tcttcaatgt ttacttgaat ttctccatca ctaaattgag taacagatga ttttcctaac
     6001 tcgacgccga ctgctgctgc aattttctct gctaatgggc gattggaatt taacgcaaaa
     6061 atttttaatc ttgggtcaaa gtaatgtttt gacatgggga cctccacttt ctttttcaca
     6121 actctagaat tctacctaat aaatagtagt catatttttt aaataaatca agtgattttg
     6181 caaaagtctt agtttagata agggagtttt tttgcatatc cttctttatt gacttgtctt
     6241 gctctcgcaa ttgccagcgc atattctgga atattgtctg taattgttga cccggcagca
     6301 atcgaactgt ttttagctac ctcgacaggt ccgatgatat tcgtgctaga accaataaag
     6361 ctgtggtcgc cgacagtcgt atgatgtttg ttctttccat catagttgac gaagacaaca
     6421 ccacatccga cattgatttc ttctcccagc gtagcatcac caacataagt caagtgaccg
     6481 actttagttc ctttgccgat ttgagcattt ttcacttcca caaagtttcc gatatggacg
     6541 ttttcgccaa tttcagcttt tggtcgtaaa tgtgcataag gtcccacatc tgcatgtttc
     6601 ttgacatggc tgctttcaat gactgagttt tcaatgacga cgtgatcctc aatcctactg
     6661 tctacgattt ttgaatgtga cccgatgaca caatcagaac caatgactgt atttccttgg
     6721 atttgtacac ctgcttcgat caatgtgtct ggaccgattt ctacgcctgc atcgatgtat
     6781 gtcgttgctg aatcgacaaa gcttacgcca ttgaccatat gcatctggtt aattcgcttt
     6841 ctcatgatct catttgcttt agctaacgcg atccgatcat tgactcccat tgattcttca
     6901 aaatcatccg tttgataagc agcaactgta tggccttctt cttttaagat ttcgatgata
     6961 tctgttagat agtattcacc ttgagcattg tttgttccaa ctttgcttaa cgcatcgaac
     7021 aaagcttcgt tgtcaaaaca gtaagttcct gtattgattt cttgtacaag agcttcttct
     7081 ggtgttgcat ctttttgttc cacgattttt tctacgatcc caatatggtc acggatgatt
     7141 cgtccatatc ctgttgggtt ttctgcttgt gccgtcaaga tcgttgcact tgcatttttt
     7201 ccttggtgat attcaaaaag attgttcagc gtttcagtag tcaataatgg tgtatcgcca
     7261 ctgataacta acgttgttcc tttttttcct tccaagaaag aagcagcttg caaaacagca
     7321 tgtcctgttc ccaattgttc tgcttgtaac gcatatttac tgcgttctcc tagttgtgct
     7381 ttaacttgtt ctgctccgtg tccaacgatc gtaatcactt catctggttt cgtttcactg
     7441 acccgattaa tgatatgttc taccataggt ttaccagaaa cgggatgtaa aactttatat
     7501 aattttgact tcatgcgggt acctttccct gccgccaaaa taattgcata acgtgcgtcc
     7561 aactgcgtca ctcctaaata tagtttgctg atttcagttt atcccagtat acccattttt
     7621 tcaacaaaac aagtgatttt cttttatccc agcgttttct ggataaaaaa atagatagac
     7681 cataacgggc ctatctattt ggtaaccggt gctctcctgc caactcctcg gtcacaagtc
     7741 acactactca taaaacatga aaagctgttt tttgaaatcg tttcttgtga cttagagtta
     7801 aacggtaggc ttacaacctc ttcattaaac gtttttcaat cagctgacct tcggtattag
     7861 ctcaataaac ggcaaaatat gaggagcaat ttttccgttt attgagctaa tactcaggac
     7921 aggacgctga tttcacaacc tctagataaa cggtgttcaa aagccagttt ctcggtatta
     7981 agccaaattt atgaaaaaat gtggaaagcc attttcacaa aatttttctt actactcgaa
     8041 actaagcagc tttttcacaa cctcttattc tgaaaaataa tttcctggca caaccgtaat
     8101 atttttcgtt tgagtatcta catctttgac ataaagcagt gacgtataat catcgatggc
     8161 gcgatgaccg ttgaattttg attcggcaaa tacagtgatg ccaacaagtt ctgattcgaa
     8221 ttcttcaatc aagctcttca ttccgttgac tgttccgccg cctttcatga aatcatccac
     8281 tacaaggaca cgtgaaccac gtttcaaact tctcttagac agttccatct tttcaattct
     8341 ttcagaagat ccagacacat agttgacact tactgttgat ccttctgtta tttttgagtc
     8401 ccggcgtaca ataacgaatg gcgcattcag ataataggac acagcttggg caataggtac
     8461 gccttttgtg gctacagtca ttacagcatc gattttttca ccaaggtatt tagaagcaat
     8521 gattcttcca acttgacgca gcagttcagg ttctcctaac aaatcagaga gataaacata
     8581 tcctcctgga agcagacggt cttgttctga tagacgttct gctagagatt caatatattt
     8641 tttcgcctct tcatatgaaa tttcagggat gaacaataca ccacctgcag cacccgggat
     8701 tgtttccaag gttccatacc ctcgttcttt aaatgttttc ttgatgattc ccaaatcttc
     8761 actgatagaa gatttagcag attcataacg ttcggcaaag cttgttaagg aaatcaattc
     8821 atgcgggtga ttcaataaat actgtgtcat gtcaactaga cgttcactgc gacgtacttt
     8881 cacctattcc aactcctttt aagaaatttt atcgttttac attatataag tttttcttca
     8941 aaaattcgag cattttatga aaaaataaga aaatagttcg gtatttatta aaataaaaag
     9001 aagcctataa aaaatttttc gtttttataa ggcttctttt ctttataatt tagttatttt
     9061 ttcttctgaa ggcaaccaat attcgtttga tgatatttac aatcaggaac aaagcaataa
     9121 agactaatgt gattgttgct cctggaggtg tatctagata aaacgagcta gttagtcctg
     9181 acagcatccc tagaaatcct acacaaacac tgatagcaat cacgacattg aagcttttgc
     9241 ctaatcgcat accgattgct gcgggaagaa ccatgattgc ggatatcaaa agtgcaccgg
     9301 caatcgggat catcacagca atagccacac cagtaatcac attgaacatc atcgacatca
     9361 aatgaacggg tagcccatcc acgtgggcgg tatcttcatc aaaagtcaga acatacatcg
     9421 gccgtttgaa taaaaagaac aatataccga tggcaacgaa taagattcct aaaaagatga
     9481 cttgctccca tgtaatggtc acgatcgaac caaacagata ggattggata cttgttgctg
     9541 aattccctcc gctcaaattc atcaatacta acgctagcgc caaaccacca gccattaaaa
     9601 tggcaatgga gatttctgaa taggttcggt agatcgttcg cagatactcc aatatcacag
     9661 ctgctaatac aacgactagc atggtcgtaa gtgtaggatt aaggttcaaa aagaatccta
     9721 acgctacccc tgctaaagag acatgagaaa gcgtatcagc catcagcgat tgtcttctga
     9781 tcactaaaaa cacacctagc atcggggcga ttccggcaat gaagatagcg gcaagaaacg
     9841 ctcttctcat gaattcatat gaaagcaacg ccattgagaa tcctcctttc tcaccagtcg
     9901 gatctgtctg tccgcatact gtttgatatc ttcatgatca tgggtgatca ttagaactga
     9961 tttcccatgg acatgcgcac tatgtcggag aagacgataa aattcatttc tggattcttc
    10021 atccatacct gttgttggtt catcaagaac aaataagtca gggtcagtag caaaaatacg
    10081 cgctaaactg attcgctgct tttgtccgcc agacaattca cctattcgcc gatttcgcat
    10141 atcccacatc cctacagctt ctaaagcacg ctgtacatgt tgatgatctt tttcagagag
    10201 acgcttgaac cagcggcctc ttggatatct tcctgaacgg actaattcga tcaccgtact
    10261 aggaaaacct gcattgaaag atgcaacttg ttgaggaata taaccgatac ttaatttttt
    10321 tccttcttga tttttctcag caatctttat cattcctttt gaaggtttca gtaatcctaa
    10381 cgatgctttc accaaggttg acttggctgc tccattttct ccagttaaaa tgacaaattc
    10441 acccgcatct acatgataag agacatcttc tagtacaggt tcatcatcat agtaaaaggt
    10501 caaatcagat atttcgatat aacgcacctt acaacctcca ttctaaaact taattgatac
    10561 tttcttttaa agctttcaga tttttttcca tgacagaaat ataattttcg cctgctttga
    10621 tttgttcatt agtcaagctt tctaaaggat tcaacacttc tagcttcact cctgtttcat
    10681 tcgacaatgt ctcagctacc ttcgaagagg cattttcttc aaaataaatc actttgatgt
    10741 tgtttttctt cacaaattct tttagctcag ctaagcgact tggtgtgggt tcctgatctg
    10801 gtgaaacgcc cgaaatcgct acttgtttta agtcgtattg attcgctaaa taagcaaaag
    10861 cagcatgctg agtgacaaat gtgcggtttg ttgcatcttt tagctcatcg gagtattttt
    10921 gatccagtgc ttcaagcttt ttgatataag catcggcatt cttcgtaaaa gtttcctttt
    10981 tatctggata tttttcgcct aattcttcag caatcgttct gacttctttt atagctaata
    11041 ccggatcgag ccaaacatgt ggatcgtatt catgtgaatg accatgccct tcttctgatt
    11101 cttcatgttc gtctgcttct tgcgattcta aacggtcgat tcctttagct gcttcgatca
    11161 tcaaggtctg tttgctatcc actgaatcct ttaacgaatc cacaaaaaat tccatgtctg
    11221 aactattata cacgaaaaca tctgcatcgg aaatttctgc tctttctttt gcacttggtt
    11281 cgaaatcatg cggctccgtt ccagcaggga tcaaaagttt cacgtttcct tcatccccta
    11341 cgatctcttt tgtaaaatca tacatcggat aaaaagtcgt aacgatcgtc aaatcctctt
    11401 ttttgtctgc ttccttgttc gtatttccac atgctgcaaa cagtaaagca cctatcatta
    11461 ccgtagctgt caaaagatat tttttcattt atatgctcct ttcaatgaac aaatcggaat
    11521 tttacgattt attaacgtga actaatgtat caaaataaaa aaacacagtc aatagaaatc
    11581 catcaatttc tgatttaagc atgtatattc ttgattaaat cgtaaaatgg atgagttgct
    11641 gctcatatct agccatttca ctacaataaa aaactgaaga ataccatttt aggattcctc
    11701 agtttttcat cacctatttt acttcttata ttttattgca gggttcgtac taaataaact
    11761 tcctcacaaa aaccttttaa cccattatat actctctgcg ctcttgaata atgttgacac
    11821 aaggcaaaaa cggttggtcc gcttccactc atcaatgcag catctgctcc gtacttgatc
    11881 atacgctctt tgatttgatg gatgactgga tgccgctttc ccgttatatc ttctaaactg
    11941 tttcccattt ttttgatcat ctgctgataa tcttgctctc ggatggcttc agcaagtccg
    12001 tggatgtctt gatgttggat ggcttgcgta tctacttctc taaacactgt acgtgtagag
    12061 acactcattc ttggtttgac caacacaacc cagcactgtg gcatagaagg taatacttgg
    12121 atttcttccc ctttgccacc gacaaatgcc gtacttccgt agacacagta aggaacatct
    12181 gtaccgactt ccaaaccgat ttctgccagt tcttctaacg aacagcccag attccataat
    12241 tggttgatcc ctcttagagc agctgcacag tctgtacttc ctccgcctaa tccagctgct
    12301 actggaatat tcttcttaac aaagatcttg acaccggttt tgatattgta tttatttttt
    12361 agcaataaag cagcttgata aacattgttc cgttcatcta ccggtaaaaa tgctttattt
    12421 gtttctacaa tgattttgtc ttctgttatt tcttcaaaaa atagatgatc tgccaagtct
    12481 acgctcgaca tcaccatttc caactcatga tacccatctt gccgtctata taatacatcc
    12541 agtcctaaat ttatcttggc tggcgctttt tcaatcaatt ccatcctctc acccattcga
    12601 aaagtctaag tcgcaagtat tctatcatag ggaaaaataa aagtatagct tatgtctgcc
    12661 tagtggttga ttttgtcatc gtttcaacag ctttcacaga attttctctt cataatccaa
    12721 acaagttcta gtgattctta taattctgtg agcacttctt ctgccaaact cggaacattt
    12781 cctttttctt ttcctatcag actgagtagc tgcatggtag caaatccgaa attacttcct
    12841 ttcctataag caaaataacg tccttcccaa tgatcgacat attttaattt cttttcataa
    12901 gcagactgga aggaatagaa aaaattacca taattatata cgatatgcat gactttttct
    12961 tgaaagaaag aaaaatctgt ttctccaaca ttagctaatg gagctaagcc tagattggct
    13021 tccgagtagc ccattttctc gtatacaata aacagattgg ctaacagata gtcagctaat
    13081 tcctcagatt ctttaggtaa gacccgcaac aaatcatatc ccgcctgctt cttcgtcatc
    13141 ggctgagcgg tgatgaagcc aacgactttt tgatctttac ggacaatacc gacaccgcta
    13201 gataatacat atgatttatc aaatcgtccc acagagaagt atttttctcg tgcaccttga
    13261 agccattttt gtgaaacttc atttacagct tgatgtaatt cttccggcag ttgatcgtac
    13321 caagtaaaat ggtatccttc tttcatcaaa cgttgatatt caagttgctg actcagccga
    13381 gacaagtctt ctgttgctag atcaacaatc cctgcttcac ctactttcgt gaagtgaaaa
    13441 cccaattcat gaagcatcac tacgtagctt tctgatatct tataaaacgc aagctgatag
    13501 cctaaacaat ctgcttgttt cataaactga ttcgttgctg cccgcatcat tttaggattg
    13561 ccaactggat ctcctaaaac aaagcatttg tttcctttga tctgataacc aaaaacgact
    13621 tgatcttggt cgtcttcttg gtaataaaaa taactgtaac ctgacaagcg aagctgatgg
    13681 cttgtagctg tgcctccgta tgtttccaat aaacggtcaa aacggtcttt ttcgtactca
    13741 ctgccaagct tcgtagtatc ttcagctaaa tattgataaa gcgccactaa agctagcaat
    13801 gagatgccca aaccaataag ccctgagaac cacacatcat ctgaaggaaa caaaataaaa
    13861 tgatttcctg ttattcgacc gactaaaaag cgtccgctgt gatagcctgc aattgcgtaa
    13921 acgataaaca aaaagccgaa caagctagca tcaaagatta tagctcccca agaataaacg
    13981 aattttgttc gataaaattc ttttctggat aaccacacag ctaacagaat caagacatat
    14041 accaatatca actgccaaga taacgtacgt gtgattgtat ttaaaatacc aaaagatagt
    14101 aaagcaatcg taggcagaaa tgcctttttg acttttactg aaagtgctct agcaaggccg
    14161 agtaataaaa agccaaccaa tagattcact gtctgatcta aaaaattgaa tgagaacggc
    14221 aataatactt gaaatagccg actgattgca gacagattag tgattgttga tagaagtacc
    14281 atcatgatcc ccgcaaaata gacagcactt acgagcacga tatgcgcaac cttttggaaa
    14341 aacagtcgcg gaatgttatc taaaaatcga ttgattttga ctcctgtatg tgtgatgaac
    14401 aatagaagtc ccgtcataaa aggtagaaca taataaaaca accgataata taatagccaa
    14461 actactgcta catcttgccg aacaggcaat tgactcattc ctaagatcat caaaacgtca
    14521 aaagtcccca ttccacctgg gaccatcgtc agcattccta tcaatgtagc aatcatgaac
    14581 ataggataga tcgaaagcat cgaaatatct attctcatca acttgccgat gatcaaaaat
    14641 accgcaaggg ctcccgtcca ttgtccaaag gatgccagta gcagaccaag caagcctttt
    14701 ggataaaact cgaagaacaa tgtctttctc tttagataag caaaaaagaa aatgactggt
    14761 gctaaaaaac taccgccgaa aagccagatc caatagcttc gaaaaatact ttctgactga
    14821 ataaaaaaga catcaataaa tgtaagaaac gaccatacag acaaaccagt cagcataaat
    14881 agtgcgactt ttgatacagt ggctaaaacc atttttctat ttgtctgctt tccataaaaa
    14941 ctagcccgca gacttgctcc taccacacca ccaaaaccgg cgagattgtt gatcgtgttt
    15001 gttacccacg cagcaagaag aaactctttt ctttccattt ttggttttcc ttgtttttct
    15061 aagactctga tcgtcaccca atcatacaac aacatcggag tgacacccag cagtccagcc
    15121 agaatcatga gcaggatcgt catgcggctt tgttgtccca tcctttgcca aatatcttgc
    15181 caactcatgc cattagcaat atttgcgact tgatttgcca caaagactaa cacggagccg
    15241 aaaaaaatca gttttaaaat cagactatgt tcctttatcc attgcagcat caagtatcgt
    15301 ttatttttca cattttccca ttcctaactt gtatactttt gtgtcatacc ccaatgttat
    15361 cttatttatt ttaatttttc cactttagac ctgttctttg cttgcgatga tagaaaaaga
    15421 aagatatcct aatgctaaag gagaggataa catgaaagta ggatttatcg gcacagggaa
    15481 tatggcacaa gctattattg atggtttatt aaaaaaagga acagtctcga aagaagaggt
    15541 gttcgtttcc agtggacatt ttgaaaatgc acaaaaattt gctgctgaaa ctggcgtcca
    15601 tgcatgcaaa agtaatcagg aagttgcatc acaatcagat atcgttcttt tagccgtgaa
    15661 accaaaaatc attgaaaaag tattggaaga actaagagaa tatagccaga aagtcttatt
    15721 catttctatt gcttcaggaa aatcattaac agatttagaa acagcgcttg aagatcctca
    15781 ggcctccatc gtacgtgtga tgccgaatgt caatgtcagc gtaggagcag gcgtttctgc
    15841 gatttgcaaa aatgaagctg ccacggagga acagcttcag caagctacga tgatttttga
    15901 agcaatcggc agcgtctatc ctttagcaga atcagatttc agtacattca ttggccttgc
    15961 tggcagctca cccgcattcg tttacatgct gatcgatgcg atgggacgga ctggtgtact
    16021 gaatggtttg tccaaacaga cagccactga gattgctgca aaagcaatta tgggttcttg
    16081 tcaaaaattc ctttcaagtg ataaaaatcc atgggaactt gtagaccaag tttcttctcc
    16141 tggcggtaca actgttgcag gtgtagttgc cttagaagaa gcaggattca tcccagcaat
    16201 catcaaagga atcaatacga cgatcgagaa agatcttgag atgttgaata aaaaataatg
    16261 atagcaatgt tttttcgtgc cttacaaaaa aagaagagct gtggcttttg ccgcggctct
    16321 tcttttgtat tttttattat ttagcataat cagttgcacg agtttcccga ataacgatta
    16381 ctttgatgtg tccaggataa tccagttctt cttcgattcg tttacgaata tcacgtacta
    16441 aacgaacagc gtctaaatcc gagatttctt ctggcttgac cattacccga acttcgcgtc
    16501 cagcttgaac tgcgtaactt gattctacac cggcgaagct gttcgaaata ttttccagac
    16561 ttcttaaacg acggatgtag ttttctaatg attcacttcg cgcaccaggt cttgctgctg
    16621 agagcgcatc tgctgcagct acaaggacag agataacaga agtagcttcc acatctccat
    16681 gatgagaagc gatcgcgttg attactactg ggttttcttt gtacttggca gctaattccg
    16741 caccgatctc aacgtgagat ccttcaatct catggtcaag tgctttccca atatcatgga
    16801 gcaacccggc acgttttgct aattggatat cttcgccaag ctctgctgct aagataccag
    16861 ctaattttgc aacctcgacc gaatgcttca agacgttttg tccataacta gttctgaatc
    16921 gcagacgtcc gatgatcttg attagatctg gatgaagtgt atgagcaccg acttcaaacg
    16981 ctgcctcttc cccgtattcg cgaatacgtt catccatttc tttacgagat ttctcgacca
    17041 tttcttcgat acgcgctgga tggattcgtc catcttgtat cagtttttcc aaggtcatcc
    17101 gtgcgatttc tcttcggatt ggatcgaatc cggaaagaac aactgcttcc ggtgtatcat
    17161 cgatgattaa atcgatacca gtcagcgtct caagcgttcg aatattacga ccttctcgtc
    17221 caatgatacg acctttcatt tcatcattcg gaagggtaac gactgaaaca gtcgtttctg
    17281 aaacttgatc tgctgcgcag cgttgaatcg ctaatgataa taagtttttc gctttgcgat
    17341 ctgcttcttc tttggcacgc tgttcagatt cttttaccat tagagttaac tcatgattca
    17401 gctcttcttc agtcgatttc atgatgacat ctcgtgcgtc ctcttttgat aaaccagcaa
    17461 ttttttctag ttctttttgt tgatcttcaa tcattttttc aacgtctttt tctcgctctt
    17521 caattaattg ctgttttgaa ctaagtgctt cttctttact ttcaagtgag ttctcgcgtt
    17581 tttctaacga gtcatcttta cgattcagcg tttgttcgcg ttgaatcaaa cgattctctt
    17641 gagattttaa ttctaactta ctttctctca gctcactttc aacttcagaa cggtatttct
    17701 gattttcttc cttagcttct aacaatgctt ctttttttag agtttctgct tctttttttg
    17761 cactatcgat gattccagca gctgatgatt gtgcaccagc tatttctttc tcgtgacgtg
    17821 actttgcgac cataaaccct aaaccaagac cgacaattaa accgatgata gcgaggagaa
    17881 tgttgaatac cataaaatcc acctccatac tatctttttc atttttatca tctatacagc
    17941 ttctatgata aattattcta aactcgtcaa tatgcatctt cgcatatatg tgtacaaaaa
    18001 acatgcacaa ctttattcta atgtttgtac cccgtagtgt caactttaaa taaacaaaga
    18061 aacggctttc tacttattca ttaaacgatt gtttttaaaa taaatgacac tagtttcata
    18121 taggtaaacc tttaaattga gaaacttttc tatt
//
LOCUS       DAJSMK010000047        16842 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.049, whole genome shotgun sequence.
ACCESSION   DAJSMK010000047 DAJSMK010000000
VERSION     DAJSMK010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16842)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16842)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16842
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.049"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            163..1104
                     /locus_tag="ON488_001648"
     CDS             163..1104
                     /locus_tag="ON488_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HCR3231844.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1173..1904
                     /locus_tag="ON488_001649"
     CDS             1173..1904
                     /locus_tag="ON488_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HCR3231845.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2048..4228
                     /locus_tag="ON488_001650"
     CDS             2048..4228
                     /locus_tag="ON488_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HCR3231846.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4248..4730
                     /locus_tag="ON488_001651"
     CDS             4248..4730
                     /locus_tag="ON488_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HCR3231847.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            4746..5507
                     /locus_tag="ON488_001652"
     CDS             4746..5507
                     /locus_tag="ON488_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HCR3231848.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            5638..6972
                     /locus_tag="ON488_001653"
     CDS             5638..6972
                     /locus_tag="ON488_001653"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HCR3231849.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7279..7764
                     /locus_tag="ON488_001654"
     CDS             7279..7764
                     /locus_tag="ON488_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HCR3231850.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            7757..8440
                     /locus_tag="ON488_001655"
     CDS             7757..8440
                     /locus_tag="ON488_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HCR3231851.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8566..11211
                     /gene="polA"
                     /locus_tag="ON488_001656"
     CDS             8566..11211
                     /gene="polA"
                     /locus_tag="ON488_001656"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HCR3231852.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11256..12092
                     /gene="mutM"
                     /locus_tag="ON488_001657"
     CDS             11256..12092
                     /gene="mutM"
                     /locus_tag="ON488_001657"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HCR3231853.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12056..12685
                     /locus_tag="ON488_001658"
     CDS             12056..12685
                     /locus_tag="ON488_001658"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HCR3231854.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            12737..13069
                     /locus_tag="ON488_001659"
     CDS             12737..13069
                     /locus_tag="ON488_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCR3231855.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13381..13872
                     /gene="nrdR"
                     /locus_tag="ON488_001660"
     CDS             13381..13872
                     /gene="nrdR"
                     /locus_tag="ON488_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HCR3231856.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            13895..15268
                     /locus_tag="ON488_001661"
     CDS             13895..15268
                     /locus_tag="ON488_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCR3231857.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15268..16194
                     /gene="dnaI"
                     /locus_tag="ON488_001662"
     CDS             15268..16194
                     /gene="dnaI"
                     /locus_tag="ON488_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HCR3231858.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16323..16763
                     /locus_tag="ON488_001663"
     CDS             16323..16763
                     /locus_tag="ON488_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR3231859.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         5749 a         2949 c         3709 g         4435 t
ORIGIN      
        1 tttttctgtg cgaaacagga aagcgaagtc tttttaattc aaataataat attatgtaaa
       61 caaaaaactt tccatgcgta attatacaca agcaaataaa tcgtcaaatg cgaacgcctt
      121 ctttatactg tttaggaacg aaaagaagga aggaagaaat acatggatta tcaagtactg
      181 ctttattaca attatacaaa aatcgaagaa ccagaggaat ttgccaaaaa tcatttagcc
      241 ttttgcaaat ctttggatct taaaggtcgt attctagtag ctgaagaagg aataaatggt
      301 actgtgtctg gaaccgttga aaacacgact gcctatatga aagcaatgaa agctgatcct
      361 cgatttgctg atacgatgtt caagatcgat ccaagcgaag gacatgcctt taagaagatg
      421 tttgtaagat accgtccaga gcttgtaagt ttaaagctag aagaggacat tgatccaaac
      481 caagtgacag gtgcctatct ttcaccgcaa gaatttaaag aagctatttt agatgaacag
      541 acagtggtga ttgatgcacg gaatgattat gaatatgact tgggacattt tcgaggggct
      601 gtacgcccag atatacgcag ttttcgagag cttccagact ggatccgcga gcacaaagaa
      661 gaatttatgg aaaaacgggt agtgacctac tgtactggtg gcattcgttg cgagaagttt
      721 tctggttggc ttgtccgtga aggattcaaa gatgtcggac agctgcatgg cggtattgct
      781 acttatggta aggatcctga agtccaagga gaattatggg acggcaagat gtatgtgttt
      841 gatgaacgga tcgctgtcga tatcaaccaa gtagataaac aaatcgtcgg tcgcgactgg
      901 tttgacggaa caccatgtga acgatatatc aattgtagca atcctgagtg caatcgtcag
      961 attcttgctt ccattgaaaa tgaagaaaaa catttaggag catgtagcat agagtgtgcg
     1021 aaacatccgc gcaatcgcta tgttcaagac catggaatct ctccagaaga agcagaactg
     1081 cggtttacag ctttaattaa atagaaaaca atagttttga ttgtcgacca tttccaatat
     1141 gcgctatact agcgttgagg atggtgatcc acatgaaatc attgatttat gctattgggg
     1201 atgtccatgg caaacatgag ctttttgaaa aacttattca ctattatgat ccaaagatcc
     1261 atcagcttgt tttattaggg gatctcaatg atcgaggtcc tcgtacaaaa gaatgttttt
     1321 tattaggaaa gcaattagtc gaagaaacag gagccattta cctccgggga aaccatgaag
     1381 aatatttttt gcaatttctg caatcaccgg aggactggta tgcgccttat atgagaaatg
     1441 gtggaaaaga aacgtttgaa agcctgattc acccaggggc atcggaggaa tactccccaa
     1501 ctgaaatctc gatgatgatc caatcgagat attcagaact gattaaattt ttagtccagc
     1561 gccccttgta ttatgaatgg gaaaattatc tttttgtcca tgccggtgtg gatttgacaa
     1621 agaaagactg gcgtaagaca agtctaagag actttatttg gataagggaa ccatttcatg
     1681 aagggaaaaa caatacaggt aagacaattg tatttggaca tacgattaca ccaatgctcc
     1741 atggagatat gcagacaaca gacctctgga ttcaggatca taaaatcgga atggacggtg
     1801 gggctgtatt cggagggtca ttgcatgggg ttgtttttga caaggaaggt attcttcaag
     1861 atattgaata tcagaacaac gaaggacctt ggcatggaat ctgactaatg gaaagaatga
     1921 aggagctgtg actttgttgc ggctcttttt atttttatag agaatattgt ttctttcagt
     1981 agtttaaccc aggataaaaa gtatgataga ataaagaagc aatttttagc agaaaagagg
     2041 cattttaatg acggaaaatt tgaaccagac gatcattcag cttgtacaaa aagaactttc
     2101 agactatcgt cctaagcagt tgactactgt acttaatttg ttaaatgaag gaaacactgt
     2161 tccttttatc gcgcgttacc gaaaagaaat gactggaagt cttgatgaag tccagattcg
     2221 tgaaatcgaa gagcggtatg cctatcttga aaacttagaa aaacgtaaaa ctgaagtgat
     2281 tcggctaatc gatgaacaag ggaaactgac tcccgagtta gaagcagaaa tcacccaagc
     2341 cgtgaaaatg caacaagtgg aagatttgta tcgtccatac aaacaaaaac gacggacaaa
     2401 agcaacgatt gctaaagaaa aaggacttga accactcgcg aagtggctga tgcagcttac
     2461 agatggagag gtgcaatctg aagcagaaaa atatattgac aaagaaaaag aagtctcttc
     2521 tgccgaagaa gcgttgcacg gtgctcatga gattattgct gaacaagtca gcgataatgc
     2581 aaaatttcgg acttggattc ggtcttatac gtataacaaa ggtatgtatg tcagcaatgt
     2641 caaggatgag caagcagatg aaaaaggcgt atatgaaatg tattatgact ttgcagaacc
     2701 cgtccataaa atggtttctc atcgaatatt agctactaat cgtggagaaa aagaagatat
     2761 tctgaaagta ttctttcaag tagatgaagc agcaatttta gcttacttgg atcgccaaat
     2821 agtcaaaaat cctgcctctc cttcttcttc attcgtcaga gaagcctatc aggatagtta
     2881 taaacgcttt attcagccag caatcgagcg agaactgcgc aatgaattga ctgaaaaggc
     2941 agatgagcaa gcaatcgcta ttttcggcga aaacctccgt aatcttttgt tgcaaccgcc
     3001 actaaaaggt aaagttgtcc tgggatttga tccggcttat cgtactggat gtaaactagc
     3061 agtcgtagat gcgacaggga aagttttagc aatcgaagtt atttatcctc ataaacctgc
     3121 agcgcaagca aaaagagaag ctgctggacc agcttttatc caattaatta ataaatatca
     3181 agtagatatg gtagctatcg gaaatggtac agccagtcgg gaatctgaac tttttgtggc
     3241 tgagcagttg aaatccgccg accataaaac ctattacgct atcgtcaacg aagcaggcgc
     3301 ttctgtttac tccgctagcg aaattgcacg aaaagaattt ccgcatctac aagttgaaga
     3361 aagaagtgct gtttctattg cccgtcgcct gcaagatcct ttagctgaat tagtcaaaat
     3421 cgatcctaaa gctgtcggag taggccagta ccaacatgac gtttctcaaa aacgtttggc
     3481 tgaacaattg gattttgttg tggaaacagc ggttaaccaa gtaggtgtgg atgtgaatac
     3541 agcaagcccg cagctcttgc agcatatatc aggattgaat aaaacaactg cccaaaacat
     3601 tgtcatttat cgtgaagaaa acggagaatt caccgcacga actcaattga aaaaagtgcc
     3661 acgcttagga ccaaaagcat atgaacaagc aatcggattc ttgcgagtcc ctggtgggaa
     3721 aaacattttg gacaacacag gtatccatcc cgaaagttat tctattgcaa aagaaatatt
     3781 aacttcagtc caactttcag aaaaagagct tggtacagaa gaagcagtag aaaaattgac
     3841 acgattatcc gtagagaaac tggctgaaag cctatcagtc ggagaagaaa cgttagccga
     3901 tattttagct gggctgacac aacctggacg agatatgcgt gatgagatgc cagcgccctt
     3961 attacgtaca gatgtattga gtatggaaga cttgaaacca gggatggaat tgactggaac
     4021 ggtccgtaat gtcattgact tcggcgcatt tgttgatatc ggtgtgaagc aagacggact
     4081 tgtccatata tcgaaactca gcaaaaaatt cgtcaagcat cctacagatg tcgtgtcagt
     4141 aggagatatc gtaacagttt ggatagaaca agtcgatacg aaaaaaggca gaatcagttt
     4201 gacgatgctt tccccttatg aagagtaaca atgaggagta acaaaaattg acacaagaag
     4261 aactgcagca gttagtagaa gagatatcat taaaaagctt ccagcttcct ttcaagcacc
     4321 aagcaatgtt caatccacgc ttacgtacaa ctggcgggcg ctatcattta aacgatcatc
     4381 atttagattt taatgcgaag ctatttgaag agtcagacga agagacgatt gcaggaatca
     4441 tcaaacatga actttgccat tatcatcttc atctagctgg aagagggtat cagcataaag
     4501 atatggattt caagtatctt ttgaaaaaaa caggagggtt gcgctatgca ccagccttga
     4561 cgaagaaaca gataaagatg gagtattatc gatgccaaga ttgttctgcc acgatctgcc
     4621 gcaagagaag aatcgatgta cgcaaatatc gttgtggaag atgtcatgga gaaatcaaat
     4681 ggattgagac aaaaagagaa gactttaatg aagcacaaaa aatcagatga aaggatagaa
     4741 ggcctttgga aaaaagtgag cagaggaatc taaaagactg gaatcagcta ttaaattttt
     4801 tagccgcacc tgaagaggga aattttgagg aactgacggc acctacactt attttagctg
     4861 gaaactgtct tcctatctta gctgataaag cagcacaaat gtatttaaat ggccaagtag
     4921 atcaattgtt tttggtcgga ggggtggggc atgcgactag aatcctttat gagaattttg
     4981 aaaagcaagg atttcatttt gaagatggca tgagtgaaag tgaaatctgt cgtcagtatc
     5041 taaaagaagt ctatgatttg cccgataagg cttttctgat agaatcgaag tctacaaatt
     5101 ctggagagaa cgccactttt tcactggaga ttcttcattc cttaggagct gtaccagaaa
     5161 aaatcttatt gatgaatgat ccgacactgc aacgcaggac tcgagcaact tttgagaaag
     5221 tatggcaaaa tgaacaaact attttcgcga atgctgtgcc atttgtgccg gaaatccttc
     5281 acttttctga agagatcatc tttacagcaa aagaactgaa tcatcaatgg cctaaggaat
     5341 atttccatgc gctagtatta ggagaaatgg aacgtctcca tgacgatgag aacggctatg
     5401 gtccgaaagg aaaagatttt attcctcaca ttgatatatc agaggaagtt tggtcttctt
     5461 acaccagaat taaagagtca ataaaaacgg atttttctcg tacttgacca ttttagcaag
     5521 cgaatcctcc tttccaaata aatttggttg aaattttcaa tcgtttataa gataatgagg
     5581 agcgtgttga atgtaatagc taaaagaatg gacgctagat aagagaagag gattcaaatg
     5641 gaaaatcaaa ataaattgta tcattttgtt ggtatcaaag gttcaggaat gagctccttg
     5701 gctcttgttt tacatgaaca aggtctaaat gtccaaggat cagacattga aaaatatttc
     5761 tttacacaaa gagatttaga aaaagcaaat atcacgattc tgccatttaa cgcagataat
     5821 gtaaaaccag ggatgacgat cattgcagga aatgcatttc ctgattcaca tgaagaaatc
     5881 cagcgagcaa aagaattagg tttggaagtg attcgctatc acgactttat tggtcatttt
     5941 atccaaaatt atacgagtat cgctgtaaca ggctctcacg gaaaaacaag tacgactgga
     6001 ctgctctctc atgtattgag tggtgtccgt ccaacaagtt atctaattgg agatggaaca
     6061 ggacatggtg atccgcaagc ggaattcttt tcatttgagg cctgtgaata tcgccgtcat
     6121 ttccttgcct attcaccaga ctatgcaatc atgaccaata tcgattttga tcatccggat
     6181 tattatacaa gtatcgacga tgtatttaca gctttccaaa caatggctgg acaagtgaaa
     6241 aaagctattt ttgcgtatgg tgacgatgct tatttacgca aattaaaagc aaatgtgccg
     6301 atttattatt atggtgtcac agaaaacgat gatatccaag cacgaaacat cgaacgcaca
     6361 acttctggtt ctgcttttga tgtctatcat ggggatgaat ttgttgggca cttcactgta
     6421 ccagcattcg gtaaacacaa tatcttaaat gctttaggtg ttattgcagt agcttatttc
     6481 gaaaaactgg atctgaaaga agttgcagaa gaaatgctga ctttcccagg agtaaaacgt
     6541 cgattcagtg aaaagatcgt agcagacatg accgtagtcg atgattatgc gcatcaccct
     6601 gcagagatca aagcaacgat tgatggcgca cgccaaaaat atccagataa agaaataatt
     6661 gcagttttcc aaccccatac gtttacgcgt acgattgcat tgatggatga atttgcagaa
     6721 gcacttgatt tagctgataa agtttactta tgcgatattt ttggttcggc tcgggaagaa
     6781 caaggaaacg ttaagattga agaccttgga gcgaaaatca aaaaaggtgg agaagtcatc
     6841 aaagaaaata atgtatctcc attgttagat tatcatgatg cagtagtaat cttcatgggt
     6901 gctggagatg ttcaaaaatt tgaacaagcg tatgaaaaac ttttaagcag cacgacgaaa
     6961 aatgtactgt aatacaatta ctgcagtgtc cttataaaaa tagaaagagg gggagtggca
     7021 aaaatcttgc caagccccct tttttgcaac ttatgataaa cggtgttcaa aagcttgcat
     7081 ctgcggtaat aagcccaatc aaatcaaaaa catgagaagc tgttttttct tggctgttct
     7141 tattatttga tgcaggacag ctttttcacg acctctgtaa actataggaa tctgttaaat
     7201 caagggagca gaacttgcct tttacgctac ttttggtaca ataatgtatg attaaaaata
     7261 aactggaggg tttctatctt gaacataggt aagccgagaa aactaggaaa aacaataaat
     7321 gaaatcgagg aaggcgactc gttatcctta acagaatcta ttgaagataa ccagcttttg
     7381 ctgtatttgg gattgacgaa tgatgcaaat cctttgtata tccaacatga ctttgcacaa
     7441 aaaacagaat atcaacagcc aatcgttcca tcagtgatgc tgatggggat catcacaagt
     7501 gcaatttcaa agcatcttcc tggaccagga tcacatgttg tcaatttttc tgtcaatttt
     7561 attgaaccgg ttttccatta tgaaacactg acttttcagt ttgaggtcat aaaagtagat
     7621 aagatgaagg atgtggtgac gatttctgta gaagcggaga atacgaacga agatcgtgtg
     7681 ttggatgctg tcgttatggt ccaaccgcca caagttcctg aattggaaat agcaatcgaa
     7741 agtgaaggtg aattgaatga ataatccaag tacatcaatg tcaggtatca atcgttttta
     7801 tgcaaaagtt tatggatttt taggtatggg acttgccctt agtgcagtca cttcttactt
     7861 ggctctttgg gtatttcctt tgcaattagc aacttttatc aataattttc cactaggctt
     7921 tgtgggtctg tggatcgttg aactgatttt agtaatggtt ctaggcgtaa aagcacaaaa
     7981 gaatccgagc ttagcaatcg gtggatttat tgcctactct cttttgaatg gcataacatt
     8041 agcggttact cttgcatact acgatattgg aacagtaacg caagctttct tgacagctac
     8101 tttgatgttc atggggatgt ctgttgtcgg agtaacaaca aaaagagatc ttagcggggt
     8161 tggaagagca ggacaggcag ctttaatcgg agtgatcatt gcactagtct tgaacatctt
     8221 cattttgaga agtagcgtag ttgagctgtt catctcccta ctgttagtcg tcatctttgc
     8281 agggattaca gcttatgata accaaagcat ccgtaatatc tatgtccaga caaacggaac
     8341 agcacatagt ggaattgctg tattcatggc attgaagctg tatttggact ttatcaactt
     8401 gttcttggcg tttctgagaa tctttggacg gaacaactaa aaaagaaaaa aattcatcag
     8461 ttggggctat accgaattat ttggtatggt cccgcttttt cttttcgcat tccgcaggat
     8521 tctttgttag aatgaataag aactttacag taaggagtta agaagatgac aaaaaataaa
     8581 ttattactcg ttgatgggaa cagtgtggct tttcgcgcat tctttgcgct tcacaattct
     8641 cttgaacgtt tcaaaaatag aaacggtctt catacaaatg caatctatgc attcaatacg
     8701 atgtttgaaa atgttatgca aaaagagcaa ccgactcatg ttctggttgc gttcgatgca
     8761 ggaaaaacga cttttcggac agaaatgtat gcggagtaca aaggtggaag atccaaaaca
     8821 cctggcgaat tcaaagaaca aatgccatat atacgtgatt tgttgacagg actaggggta
     8881 cagtattacg aattgcccaa ttatgaagca gatgatatta tcggtacttt ggcagaaaaa
     8941 gtagacaaag atcaatttga tgtcgtcgtg ctttcaggtg atcgggattt gactcaatta
     9001 gctagtaaag aagtaaaagt ggatatcact gtaaaaggtg tcagcgatat cgaaagctat
     9061 acaccagaac atgtagcgga aaaatatgat gggttgacgc caaaacagat tattgacatg
     9121 aagggactag ccggagatgc ctctgacaat atccccggtg tgactaaaat cggtgaaaaa
     9181 acagctatca agctattgaa acaatatggc tcagtcgaag gaatttatga acatatcgat
     9241 gaaatgaagc aaagcaaaat gaaagaaaat ctgataaatg acaaagagca ggctttctta
     9301 tcgaaaaaat tggcgaccat caatacttca gcgcctgtgg atgtctctat cgactcattg
     9361 aagtatgaag ggaaaaatct cgataaactc gttccgtttt ataaagaaat ggatttcaat
     9421 cagttccttt ctaaattgaa tatcgtagaa gaagaagtaa aaatggatga tattttgttt
     9481 gaagtcgttc atgaattcaa agaggaaatg tttactacgg atatggcgtt gtacgtggaa
     9541 atgatgggcg acaattatca tacagaggaa atcgtcggag tagcgtgggg gacagaaaag
     9601 aaaatttatg tcacgaacga tctatctgta ttcgaaaacc gagcgttcca ttcttggatc
     9661 actgatccga ctcggctgaa aaaagtatat gatgcgaaac gaacttatgt tgctttaaac
     9721 cgctatactg gaaaaacgaa aggaatcgat tttgatgtct tgctaggtgc ataccttctc
     9781 gatacgaatg aaaaaagcac agatatcgaa ggaatagctg ctcattacgg atacaacgat
     9841 atccaatcag atgaagctgt atacggcaaa ggggcgaaaa aaggtttacc agaagaagag
     9901 gaactctttt ttgctcattt agcgcgaaaa gtagctgcaa tcaatgcgtt gacaccaaaa
     9961 ttgagccaag aactggcaga taaaaaccaa gaagatcttt tccggaaaat ggaactgcca
    10021 ttgtctatca ttttggcaga gatggaaata agcgggatca aagtagatgc gactcgctta
    10081 caagaaatga agggcgagtt ctctgctcgc ttaagagaga tcgaacaaaa aatctacgaa
    10141 gaagccggcg aagaattcaa tttgaattca ccaaagcaat taggagtgat cttatttgaa
    10201 aaaatgggat tacccgttat caaaaaaaca aaaactggat attccacagc cgtagatgta
    10261 ctggaacagc ttcgtgaaca agcaccaatc gtagaggata tcctcaccta tcgtcaaatt
    10321 gcaaaaattc aatctaccta tgtcgaggga ctgctgaaag tgatccaatc agatggaaaa
    10381 gtgcataccc gttatgtcca gacattgacc caaacaggac gattaagctc tgttgatcct
    10441 aatttgcaga acatcccgat tcgattagat gaagggagaa agatacgtca ggcatttgtt
    10501 cctagagaaa aagactggct gatttattct tctgactatt cacaaatcga gttacgcgta
    10561 cttgcgcata tctcaaatga tgaacatttg aaagctgcct tcctagaagg tcaagatatc
    10621 catgccagca cagcgatgcg tgtatttgga atcgaaaagg cagaggatgt cacaccaaat
    10681 atgcgtaggc aggcaaaagc agtgaatttt ggtatcgtgt atggcatctc tgattacgga
    10741 ctttcacaaa atctaggaat cagccgaaaa gcagcacagc aatacatcga tacgtacttt
    10801 gaaaaatacc caggtgtcaa agaatatatg gaaagaatcg tacgcgaagc aaaagaccaa
    10861 ggctacgtcg aaacgctgta tcaccgccgt cgatatctgc cagacatcaa ttcaagaaat
    10921 tacaatatcc gttcttttgc ggaacgaaca gctatcaata caccaatcca aggaagtgct
    10981 gctgatattt tgaaaatcgc gatgatcgaa ttggataaac gattaaaaga aacaggtctt
    11041 caagctacga tgctgttaca agttcatgat gaacttgtct tcgaggtacc ggaaaaagaa
    11101 cttgaatcat tagataaatt ggtgaaggaa gttatggaac aagctgtttc tcttcatgta
    11161 ccactgatca ctgacagcag ttggggaaaa acgtggtacg aagcaaaata aacattgttt
    11221 aagacagagc aatataatga aggtgaaaag aaaaaatgcc agaattacca gaagtagaaa
    11281 ccgttcgtaa aggattggaa cggttagtag taggaaaaac gattcaaaaa gttcaggtct
    11341 tgtggcccaa gatcatcgag caaccagaga cacccatctt tgaggcttct cttgttggcg
    11401 aaaccatcca atccattgga cgtagaggga agtttttaat ttttcatctc gatcattgtg
    11461 aactgatctc acacttgcga atggaaggaa aatatcaatt tacgaaagaa aatacaccaa
    11521 tcgataaaca tacgcatgta cttttctttt ttgaggatgg aagccaactt cgctacaacg
    11581 atgtacgaaa atttggtcgt atgacaatcg tcgaaaaagg agcaagtgca acttaccgag
    11641 gaatcatgaa attgggacct gagcctttgc cagatagctt cttattagca gatttcgcaa
    11701 atggactgaa aaagtcccac aaagcaatca agccattgct gctagaccaa cgtctagtga
    11761 ctggtctagg taatatttat gtagatgaag cattatggga agcgaagatc catccagaac
    11821 aaccggcgaa cacactgcgc cccaaagagg tagaacaatt acgtctatcg atcattgatg
    11881 ttttggatcg tgcaatagaa gccggaggta ccacgattcg cagttatttg aatgcattag
    11941 gagaatcagg cggatttcaa gtagcactgc atgtctatca gcaaactggc aaaccatgta
    12001 tacgttgtgg aacgccgatc gtgaaaacaa aagtggcaca aagggggacg cactattgtc
    12061 cgaattgtca aaggctaaaa atcgcaaagt aggatttgtt ttaggtttga cgggtggaat
    12121 agctaccggt aaaagtacgg cagccaaagt ctttcagtct catggatttc ctttgatcga
    12181 tggcgatgtg attgccagag aaactgttga gcctggaacg cttgctctga ggaaaattgt
    12241 atcagtgttt ggccaagagg tattgcagcc tgatgggcaa ctagatcgag ggaaacttgg
    12301 gatgattgtt tttccatcaa aggaaaaacg gcaaaaactt gatcagctat tagatccgtt
    12361 tatccgaaaa gcgataaaag atcaaatcgc ctctctaagt tccaatcatc ctttagtaat
    12421 tgtagatatc ccattgctct acgaaggtca ttatgaccac tatatggatg cagtagctgt
    12481 cgtttatact acgccagaaa ctcagcttca gcgtttgatg aaacgtaatc aactgacgct
    12541 agaacaagcg cagcagagaa ttagtagtca acttccaatc gaagaaaaaa agcagcgtgc
    12601 ggatattttg ttcgacaaca atggaacaaa agaaaaactt gtgggacaaa tcgaaaattg
    12661 gctttttgct aatcgctttc tttgagtatc tgtgtcaatt ttgctatcct gagtatatag
    12721 aaagtgaggg atagcgatgg gatcattaaa aaatcaaaag gataaagtcg taggtaacgc
    12781 aaaagaaaaa atcggcgaga tgctcaataa agaaaatcta atcgatgaag gtcgtacgca
    12841 atcagaaaca gcagaagaaa aagaaaagca gtaccaagca agaatcgatg aaatagaaga
    12901 ccagcaggca gaagaagaag cgaagcggca agatttgact caagaacgaa aaaatccgac
    12961 acctgatcgt agtaaaacac cgctcccaga aagtgaccac atttccgatg agcaaaaaat
    13021 cgaggaacag cgaatgaaac actatacagg aatcgaagag aagttataaa atagtaaaaa
    13081 atcgagatgt gacttgaagc agatgagaag gtgttcatct gcttcaagtt ttttgtgcta
    13141 gatgactaaa tcagcttttg tgtaagttat ttctcagtaa tcaaggtgat cagtattgga
    13201 aaattgaaat ttagtaagga caggggacac aattacgcat gaaagtagaa aaaattgttc
    13261 ttatatccgt gttttttggg taggacagtc gcgtttgtga tttgtttcgt gttataatac
    13321 aactagttgt aaagaaagac acatccttta tataaaatgc gatgcaagag gtgagacaaa
    13381 atgagatgtc ccagatgtca acataataat tcacgagtaa tcgacagccg tcaagcagat
    13441 gatggacgtg cgatccgtcg ccgtcgcgaa tgtgagaatt gttcgttccg attcactaca
    13501 tttgaacgaa ttgaagctgc tccgttatta gtaatcaaga aaaacgggga acgcgaagag
    13561 ttcaatcgcg ataaaatttt aagaggactc atccgttcag cagaaaaaag acctgtagct
    13621 atggaacaaa tggaacaaat cgtcaaccat gtcgaaaacc gcgtacgcag tctcggagaa
    13681 aacgaagtat cgacgaatct aattggtgaa tatgtgatgg aagatttagt tgatttagac
    13741 gaaatcgctt atattcgttt tgcaagtgtt tatcgccagt tcaaagatat gtctgttttc
    13801 ttaaaagagt tgcaagatat cgtggataaa gcaaaagaaa ataataaaga gaataataaa
    13861 gaaaacaatt aagaaacaaa aaggaggcat ttccttggaa aatgcttgga aagagcttca
    13921 accaaaaaat atttaccaag gaagaaaagc ggctccgctg agagaagaca gcaagaacgc
    13981 cttgctgtat ctttatcagc cactaatcgg cggagaagcc ttgagtatct atttcaccct
    14041 gttatcagaa atctctcaag aatctggcaa aggtcctgaa gggatgcatg cagatctgct
    14101 tagtagtcta ggctgcggta tcccgcaatt ttatgatgca agaaaaaagc tagaaggaat
    14161 cggcttactg gatgtttatt ttaaagaaga tagtgatctg ggacctcgtt ttatttatga
    14221 gctgttagaa ccactcattc ctaaagcatt tttcaaagac tctgttctgg cttttcttct
    14281 tctggaaaaa gttggtgaac gacgattcca gaagcttacc caattctttg aacctaaaag
    14341 gcatacagca gagggatatc aaaaaatcac aaaaaaattt ttagatgttt atcgcttcaa
    14401 tgaagcagtg tacgctgcta atcaagaaaa catcgaatcg ctgaataaat cttttgaaga
    14461 atctgaatca gtagcattac ttgaagcaga ttcgacattc gattggcagt ttttgaatga
    14521 ttggctggca aaaaaacata ttgcaagtct tgatgatcca atcatcaaac aagtcgacat
    14581 gtatcatcag ctttacggtt tcgatgaatt gacacttggc gaactgatca gtcaatctta
    14641 tgactttagt gaacaaaaag tatctgaaaa agaactgcaa aaagccattt tggcaatgca
    14701 gagacgtccg gtgaagcaaa caaaagaaac agttgcggtt tctgaaaaca gtaatgaacc
    14761 ctcgtcaaac gaacatttga caaacgcagc gcttcagctg ataaaagaag cacagagcat
    14821 tccaccgatg aaatatctgg aagcaatcaa gtcagaaaaa ggcggatatg tttctaaaca
    14881 agaaaactgg ttactgcaag atcttgtttc tcaatcaggt ctttccagta gcgtgatcaa
    14941 tgttttgctg aattatgtac tagtgatcaa gaataatgct agcttaaatg ccagttatgt
    15001 aaatacagtg gcaaatgaat gggcacaaaa gaaaatcgcc acagcagaag aagcgatcca
    15061 gcacattcgg caaataagta atcaagcaaa acaatcaaaa caaaagaagc aaacaaatta
    15121 tcaaactggc aagcgaaatg ttcgacggga aaagcttcct gattgggtca accagccaaa
    15181 agatgaaaaa cagatcagca gcgagaaaaa agcagagatt gaccgccgtt ttaaagaata
    15241 cctggcaaaa aaggagggtg atatctagtg gaagacgtag gcaaagaatt gaagaggatc
    15301 atcagcaaac gcaattatca agaaaagtat gctgaaatga tcgctgaagt cttaaatgat
    15361 gcggatgttc aagcttttct aagcgcacac caagaagaat tgacacaagc ggatattgaa
    15421 aaaagttacg ctaaattgta tgaattcgtg caagaaaagc gtaaatatca aaaaaacgat
    15481 ccaacgatga tcgctcccgg ctatgagccg aagctgacgt tgaattttca ttatgtggat
    15541 gtcacttatg taccaacgga agcattgtta gcacggcaaa gacaagaaga aatcagaagc
    15601 cgagtaaaag caatggatat gccaaaagat attcaatcgg cttcttttga aaactttgaa
    15661 cgtacagatg gacgaggata tgcgagctta gaagccctag attttgtaga gaaatatact
    15721 gctgatccaa aagggtatca taaaggactg tatctagtag gaagttttgg tattggaaaa
    15781 acatatttat taggagcaac agcgagagaa ttagcgattg ctggattcac cacgacgcta
    15841 gtccattttc cgacatttgc cgttgagatg aaacaggcaa tcggaaaaga tcaagtggca
    15901 gaaaagttag atgcagtgaa acgttcacct attttgatga tcgatgacat tggtgcagat
    15961 gcgatgagta gttggatacg agacgaagta ttcggtgtta tccttcaata tcggatgcag
    16021 gaacagttac caaccttctt ctcatcgaat tttacaatgg atgaattgga acagcatttg
    16081 tccgtcactc aacgtggaga tgaagagccg ctaaaagcga aacggataat ggaacgcata
    16141 cgttatttga caaaagaaat cgaaatgact ggtcgcaacc gacgcaatgg ttgaacagtt
    16201 gacaagtcca actgacattt gacctagtag taaaagcagg tcagcgaatc attatatgga
    16261 cagaaatgac cggagacaat caccgcaaca agtaatgcag aaacttaaac ggaggatttt
    16321 ttatgagggc tattttttct agtatatctg tagttggtct attttttctt ttagcaggct
    16381 gcggtagcgc agatagcaac acaggttctg ttgattcgat tgatgcgggt caaacagtaa
    16441 aaacaagcag tacgaaaacg gagagacaaa gcatatttgt cggaacgatt gaaagtatta
    16501 ctcaagtaga agcagaagaa gaaacgcttc agttgaaact cgtcgatgtc atggccaaag
    16561 aagatccagc gaatatggga acgtcattca gcaatgacgg agtgatctta aatgctactg
    16621 ctgaaaaaat aagcgtggac ataaatgaat tgaaaatcgg tgacaaagtc caatttacat
    16681 tagttgagat gccgatcatg acgatgtcta tcccaccgca agttcctgga gattcgatta
    16741 ttgatgtttc attgaacaaa taaccaataa cattttttca aaaataagaa aatgttgttt
    16801 tatagaacga aaaggtatat tttttaagga gatatgggaa tt
//
LOCUS       DAJSMK010000048        16814 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.050, whole genome shotgun sequence.
ACCESSION   DAJSMK010000048 DAJSMK010000000
VERSION     DAJSMK010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16814
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.050"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..450)
                     /locus_tag="ON488_001664"
     CDS             complement(<1..450)
                     /locus_tag="ON488_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCR3231860.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEK"
     gene            complement(555..1418)
                     /locus_tag="ON488_001665"
     CDS             complement(555..1418)
                     /locus_tag="ON488_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCR3231861.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(1614..3713)
                     /locus_tag="ON488_001666"
     CDS             complement(1614..3713)
                     /locus_tag="ON488_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HCR3231862.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(3933..5042)
                     /gene="rpoD"
                     /locus_tag="ON488_001667"
     CDS             complement(3933..5042)
                     /gene="rpoD"
                     /locus_tag="ON488_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HCR3231863.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(5066..6907)
                     /locus_tag="ON488_001668"
     CDS             complement(5066..6907)
                     /locus_tag="ON488_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HCR3231864.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(7089..9404)
                     /locus_tag="ON488_001669"
     CDS             complement(7089..9404)
                     /locus_tag="ON488_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCR3231865.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDHKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(9589..10449)
                     /locus_tag="ON488_001670"
     CDS             complement(9589..10449)
                     /locus_tag="ON488_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HCR3231866.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(10508..11029)
                     /locus_tag="ON488_001671"
     CDS             complement(10508..11029)
                     /locus_tag="ON488_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HCR3231867.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            11307..12068
                     /locus_tag="ON488_001672"
     CDS             11307..12068
                     /locus_tag="ON488_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3231868.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            12094..14685
                     /gene="mprF"
                     /locus_tag="ON488_001673"
     CDS             12094..14685
                     /gene="mprF"
                     /locus_tag="ON488_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HCR3231869.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(14873..16060)
                     /gene="tuf"
                     /locus_tag="ON488_001674"
     CDS             complement(14873..16060)
                     /gene="tuf"
                     /locus_tag="ON488_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HCR3231870.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            16428..16784
                     /locus_tag="ON488_001675"
     CDS             16428..16784
                     /locus_tag="ON488_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCR3231871.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
BASE COUNT         4617 a         3488 c         2946 g         5763 t
ORIGIN      
        1 tttttcatag cattcctgac agattccatg gaacgttagc cgatgatctt ttactaaaaa
       61 atgataacgt tcttctacta cttgctccac ttcaagtaaa agatcctctt ctacttcctc
      121 gatcgtgccg cagttcaagc atagtaaatg atgatggaaa tgtttggcgc cttcttttct
      181 caaatcataa cgggctaatc catcattaaa acttacttta tcgacaattt tcaattctgt
      241 caagatttca agggttcgat aaacagtagc aagtccaatt tccggactct tttttttcac
      301 taaaaagaag atttcttctg cagataaatg ctctttctca ttttccaaaa gcacaagcag
      361 agtagcttct ctttgcggtg tcagcttaaa ccccgcttca tgtagctgct gttttgtttt
      421 tttcatcgcc gaaatagcat tcatgaccat ttactcaacc ccaacaattt ataataatta
      481 caaataaaaa aagatataac actatgttaa ttaaaattat tataagctag ttaagaaaaa
      541 catgcaaggg attctcaatt agattttttg actagttttg tcacaccgtt ttcttgtgta
      601 atcaatcctt gtttcaaaag attacctaat gcgcgcttaa atgctccttt gctgatacca
      661 aaagctttca tgatttcttc tggatccgat ttatctgtaa agttgatttg ctgatctgca
      721 gaacgttcta aaatggttaa aatcatttgt gcatcatctg atatagcttc atatgctctt
      781 ggcttcaatg aaagattcag tacaccgtct ggtcggacac caatcactcg accttttatc
      841 tgctcgccta gacgaggttc attatatcgt tcagaaggat ggataaaccc aagatagaaa
      901 tcttccgtta aaacgtacgt acctgttaat ttcaagcggt atgctgttcc tatcacatct
      961 ttgtttttca tttcttctgt tccatatttg cttaaagatt tgaatatttt ttcatctgct
     1021 aaactgcccc aaatacggtc ttttgcatca actctaaggg aaatcatcaa gcgatcccct
     1081 tttttaggcc atagctctgt cattgtcggc aattcatcaa gagatacgac aaagtcttta
     1141 tctggaagac cgatatcgac aaacgcacct aaatcttttc gtgtagcagt aacgattcca
     1201 aaagcgtaat gaccgatacg gcttttagga atttgtgtag tgatccgatt ttcatgtttt
     1261 tgattttggt aaccgaatcc ttcaactgct tcaccgattt tgtgttcacc ttctgatttg
     1321 cttaagccaa aggtttgtcc gtttttttgg acaaagtagt ttttttcatt ttcatcaata
     1381 ataatacctg taaatatagt tgctaataaa tcgttcattt ttttctccct ctatagtgaa
     1441 aggttttctt aatacatttc tttgctatca taacataatg ttatctactt gaatagctga
     1501 gccttggttt ggaaaggtga aaaaaggagt atgacaacag ttgtgtcata ctcccctttt
     1561 tcgaataaac ggtgttaaac ggcaggctca cagcctcttt catttgccta aaattaattg
     1621 ctcccatttc ctccgaacca tccagtttta cagttgatgg ttacgatgta aaatggcaaa
     1681 gcactttctc caatgccttt catcaatgca gattttgttg aagtggcata tagattataa
     1741 tagccttccc cattttcgat tctggctttt tctaatctgt aacctccttc aacgatatat
     1801 ccacgttgga tacatgtagc aatcactttg ctttggacac ctggtgccca cgtccatgct
     1861 ggattagatg catcggcaat atcacttgct ctggcagatt tgattggctg attcgctgag
     1921 tttgaagagg aaggggtcga ggatgccgct tcttgctgtg ctgcttgtgc gaccgcagct
     1981 tgttgagcgg cttgagctgc agctgctgct tgagcggctt gttttgcttg ttcttcagct
     2041 gcttttttcg cttcttctgc ttttttcttt tcctcttctt cttttttctc tttatcagtg
     2101 agcatcttat ctacttgttt caattgttca ttcaactgag cagatagatc tgtatttttc
     2161 actttttcta ctgcttcttt tgccgtcttg tattggtcgc gtgttgctga atccactact
     2221 tttccgtctt taaagactat agctgttttt tctttagctg tttgcaattc agcatattga
     2281 tttttagctt ctgtttgtgc ttgttgaatc aattttccaa aatctgtgtt atccgtttcg
     2341 attgcttgga tctctttatc tgctttcaac ttgatgtcat ctgctagatg atcatcgacg
     2401 atggcaggtg ctatgaacca ctcattcact ttttggatat ctcggatctt agattggata
     2461 tcttggtaag ttgtttctaa ctctgaatat cctttttcat tcttaagact ggataaatca
     2521 ttttttagtt ttgataaatc ttgatgaatc atatctgcac gaataaattg atggtgatca
     2581 tctgtataaa aggcagcaag tttctcatga agttcttcca tttgttgctg tctttttgct
     2641 tctgctgcta cttcggcttc tactttttga tgatggtcat aataagccca gcttcctcca
     2701 ccgagtagaa gtactgctgc taaaacgaga taaggtactt tttttgattt tttcttttgc
     2761 gctttatctg gatctgtttt ttctaagttt gattcttgat gtgttttttc agtatctggc
     2821 acgattgtta ttgatttcgc ttctgcttca aacagcttag gctggttctc ttctttttct
     2881 atttttgctt caagatcagt accctctttg cttacagatt gattttcagc atcggattca
     2941 ctatttattt catcgggctc tgttgacttt ttgtctgtgt tttcgagtat ttcttttttc
     3001 tctgcttccg gcagtttatt cgttttttcc ttttctaatt gtttttcagt aaatacttca
     3061 gttttttctg tgatatccgt ttttacgtct tttattttta ctgtttcttt acctgtggcg
     3121 ttttctctat cagagtcttt ttcagtttct tgttcctttt ctggctctac tttgttttcc
     3181 tgtgcaattt tttcactgat cattttgagc agctctttcg cgtgctcttc ttttgtatct
     3241 tcacgatgtg ctttgatata agcggatagt atcgaatttt cttcctcatt atcgacgatt
     3301 tctttcagtt cagctactct tcttttttgt tttgattcaa gcgtttcttc ttgattcttt
     3361 cctgattctt ccgaagtctc atgaacagtt gctttcttct gttcattttt ctctatatta
     3421 gttacttgat cgtgagcagg tggttcttcg tcttctggtt ctgctttttc gaataattcc
     3481 attacagatt ctagaggtaa atctttcaat tccgaccatt cgattggatc gtttaattct
     3541 gtatcaggaa agactgcatc ttcagttgat ttatcctgca tagctgcatc tgtatttgtt
     3601 tcttcaattg attcttttat ttgctgatct tctgcagtta tttgatgacc gcagtctgga
     3661 cagatagtat tctgctccat ttttttcgat ccgcaatttg gacatttttt catcacttag
     3721 cgatcggctc ctttactagg tttacgctac catttaatct atcatattct atacgtcacg
     3781 ccaatagctt atttttagga tttacttaaa aataatgaat gaatttcctt cctatagaaa
     3841 aaaaagcttg agactgcgta gtctcaagct ttttttcttt taaaataaac caaacagttt
     3901 tactgatttc tcttctggtc aatagtccac gcttattcta agaaatcttt taattgtttt
     3961 gaacgagaag gatggcgcaa ttttcttaat gctttagcct cgatctgacg aatacgttcc
     4021 cgagtaacac caaatacttt ccctacttct tccaatgttc tcgtccggcc atcatctaaa
     4081 ccaaaacgta agcgaaggac attctcttcc cgatcagtca atgtatctag tacatcttcc
     4141 aattgttctt ttagtaactc ataagctgcg tgttctgctg gacttgttgc ttcctggtct
     4201 tctatgaaat cacctaagtg agagtcatct tcttcaccga ttggcgtttc aagggaaaca
     4261 ggttcttgcg cgattttcaa gatttctcgg actttttctg ttggaagatc catttccgca
     4321 ccgatttctt ctggcgtagg ttctcttcca aggtcttgca gcaattgacg ttggatacgt
     4381 atcaatttat taattgtttc aaccatatga actggaatac ggatcgtacg tgcttggtca
     4441 gcgattgctc gagtgatggc ttgacgaatc caccatgtag cataggttga aaacttaaat
     4501 cctttgcggt agtcaaattt ttcaactgcc ttcatcagtc ccatgtttcc ttcttggatc
     4561 aagtcaagga actgcatgcc tcgtcctaca taacgtttag cgatacttac tactaaacga
     4621 aggtttgctt ctgccagacg ctgtttcgct tcttggtcgc cttcttcgat tttcaatgct
     4681 aacgctactt cttcttccgc agttaaaagg gagacacggc caatttcttt cagatacata
     4741 cgaaccgggt cattgatttt tacaccggtt ggcgcagaaa gatcttctgt ttttgcttgt
     4801 tcagcttttt tctcagcact cttcaagctg tgaattgatg gatcaccatt ttcatccacc
     4861 acactgatac ctgcgtcttc aatcttttgg atcaatttgt ccatttcatc tgcattcaaa
     4921 gtgaatggtg tagcaagctg attggataaa tcatcatata caacttgtcg tttgggtttg
     4981 ttttctttga tgaaagctgc tactgctgct tcatacgttt ttttatctgt tccatttgcc
     5041 ataaaagaag gccccccttg agtagctatt tggcttgttt taactgtttc gttaaattga
     5101 tgatttcaat cgtcaattca agctcaagct gtttgtttcc agttcgtctg gcttcttgct
     5161 gcatttgttt ttttaatgtt atttcatcag ctaagccaga tttgctgatc acatctagca
     5221 agtcttggat ttctcgtggc gaactttctt ctgccaccgg taaatattcg atttccacca
     5281 ccaaccgcct taaattttca tcttgcaaaa agtctaaaaa ctctgcaagg ttgaattcat
     5341 aatgttgtga gacatatgca tcgaataaaa aataaacttc tgcatatgca tcatgaataa
     5401 actgaaattc tcgttctttt aaaatattac ggacagaaac ttctttaaat gcacgatata
     5461 atagaatctg ctctgccttt tctacttgcg tcaaaggtct ctttttccgt gcagtttctt
     5521 gtctcgtaac ctgagtgtgt tgactttcct gaggttcttg acgattttgc tgatttgtcc
     5581 ttcgaagatc gcgcagttgt ttttgtatcg tctctctgcc gatctgaaac tctgttgaca
     5641 gttgagatag atacatatct tgttcgattg gtgaaacaac tcggctaagt tcaactagta
     5701 attcttcgag gtattcgatc ttgtcttttt cattatctaa atttttccct tgttttaaat
     5761 aacgtgattt aaaagtaaag actgtttcgc gcccatgagc cactaattct tggaaagatg
     5821 cttctccata cttacggaga tattcatcag gatcaagctt ttctggaacg actacgacag
     5881 aaagtgctaa tcgactgttt tgccgaagca attcaatccc tcgattggtt gcttcaaaac
     5941 ctgcgttgtc tccgtcatag caaaagacca attctttcgt cagcttttcc atttgttgga
     6001 tctgttgagc tgttagactt gtccccatag aagctaatcc agttttgata ccagcctgcc
     6061 atgcagcaat cacatccata aacccttcga acaacaaaat ttctccgttt ttccggatat
     6121 cgcttcttgc tttatcaaga ttaaataaaa cttgtctttt attgaacagt tctgtttctg
     6181 gactattcaa gtatttgggc tgatcttttt cctgcccttt ttcaggtgca agccagcgtc
     6241 ctgaaaaacc gatcgtctgg ccttgagaat tacgaagtgg aaacatcact ctttgataaa
     6301 aacgatcaga catacggcca tcatcatgcg tgacaaacaa tccagagcgt tctaacaatt
     6361 catttgaaat tgattcattc ttgaatactt gctgaagaaa agaacgctca ttaggtgcaa
     6421 aacctatgtt gaattcttca attaattcta aagacaaccc acgactttgc aaatattcta
     6481 aagctggctg tccagctttt gtatgcaata gcatgtgatg atagatttcc gctgcttttt
     6541 catgagcagc aatcagtttc cccgtagcag attcaggatt ttggacagct atagtacgct
     6601 gacgccattg atcttctaac ggtatctgtt cgaagtctgc cacttttacc actgcttctg
     6661 gaaaacttag accttctagt tcttgaagaa aagtaaacac gtttccgcct ttaccacaac
     6721 caaagcaatg aaaaatctgc ttgtcttctg caacagaaaa agacggtgta cgttcttcat
     6781 gaaaaggaca cagccccaag taatttttac cagacttttt caactggaca tattgtccaa
     6841 tcacctcaac gatattcgtt tgactgcgta ctgtttcgat aacctcttga ggaatccgtt
     6901 gagccatttt ttcaccccct gctctattga tatcttttgg gtttaacaga agatatttca
     6961 ggagaataac cggtaaaaaa tcgcactaac tgaaatcagt gcgattttaa aggacacaat
     7021 tatacatgtt tgattgtatc atatttcatt gctttttcaa gtataacaca tttctatctc
     7081 attaagcatc aatttgctac tcttttcagt aactgatttt gaatatcagc cttccagtac
     7141 aatactcgaa gaacaatatt tacgagcatg aatacaaaga agtatcctac gctctctccc
     7201 aaccctaagt ttacttccaa aattccatgg aacagcattg cagctacata tatccctacg
     7261 atcgtcgtta ctgctaggaa gatgcgcaat gggttgaagg gataacaagc ttttacaact
     7321 gccatgcaac tgatcccaat cagcaagtaa tacatcaaag tagtagtttc agcatttccc
     7381 catgcgaatg tttttccaag tagatacacc gcaatgatat tcactactac aagcaaggca
     7441 tttggtaaag cattaataag tgctgtaggc aaataacggt aagtgatttt tcttttatct
     7501 tgttcaaaag ataaaaagaa ggaaggatac ccttcaatcg ctaaatcaat cagcgtgatt
     7561 tggataggga taaacggaaa tccaattgct gtaacggcac atataatcga taaaataaat
     7621 gaataaatcg ttttgataaa aaagatgcct gagactttcg tcacattgtt gaccactcgg
     7681 cgtccttcaa acaggacttc tggcaatgta gtaaaatcag agtccaacaa taccagattc
     7741 gcaatctgac gtgttgctcc atcaccttct gccatagcaa tgctgcaatc tgcttctctt
     7801 aacgccaaaa catcattcac accgtcgcct gtcattgcaa ccgttctgcc gctttctttc
     7861 aattcattta ccagcaattt cttttgctgc ggactcactc gtccaaaaac cgtatagcga
     7921 tgagcagctt ctcgcacttc catttcttca gtaatttgag aaagatcgac atacgcatca
     7981 taattcggta atcctgcacg tctagcgata ttggagacag taaaaggatt gtctccagaa
     8041 atcactttca gatccacacc ttcctcatga agataagcta gtgtttcttg agcgtttttt
     8101 cggattggat catcgatttc aaacagagca accggctcaa caaatgctgg tttttcttcg
     8161 ttcaattgct gatttggagc gatccccaac ataagtacgc gatagccatt cgcttgggct
     8221 gtttttagac tgtccggaag ccgatcttct tccaccaaac gttcaggcgc tcctacgtac
     8281 acgactccca gttctggaaa ttccatcgcg ccccatttgt gatcagaaga aaatgcgact
     8341 ttgtttgtca catcataccg attagaaagc tcaaaataat ctctcatagc ccgcatagtg
     8401 atgttgttat cactgctttc tgccagatac gtccccataa tttctgggat ggctttctcg
     8461 tacagcggat gtagtgcttc tacccgctgg atactcattt tcccttcagt aatggtccct
     8521 gttttatcca agcataatgt atcgacatgg gccagcgttt caattgaata catgtcttga
     8581 acaaggattc gtttttttgc cagtttggtt acccctgtcg ttaatgcaat acttattagc
     8641 aataccaaac cctttggaag catgcctaac aaagctgctg cagatgcaat aacagaaatt
     8701 ttgatagaag catcgcggat gaacagtgct tccaaaaata gtatgatccc caaaggaata
     8761 atcacgaaac tagtgaattt ggatactttg cgaatcgaat ctacaagttc agaacgaata
     8821 gctttgtgag tctttgcctc gctagtcaag cggacagcat aattatctgc acctactcgg
     8881 ataacttcag ccatgacaga accgcttgtc aaaaagcttc cagaaagcaa ttcagctcca
     8941 gtttctttga caatcaaatc agattcgcct gtcaaaagag cttcatttgc ttctgcccgt
     9001 ccagatataa cctgtaaatc ggctggtatc tgttctcctg ctccgatttt taccaaatct
     9061 cctaatacca gctctttagt agaaatcgat tgttctttac cgtcccggat cactagtact
     9121 tctgattggg aaacaatcga taatttccgt acaagatttc ttgcatgtat ttcttgataa
     9181 attccaataa cgatattgac gacaataatt gctaaatacg ccatgttgga atacgcacct
     9241 acaaataaca gacaaatccc aataccaaag ttcagaaaat tgaataacgt caatatatta
     9301 tcgctgaata tttgttttgt actttttgat gcatcttcct ggtagtcatt ttgctggcca
     9361 gaagccattt tctgaactac ctcttgctgt gtaagtccat tcattttctt tttctccatt
     9421 ttccgccaac tttcaaaaat aatcacgtgt ttaagtctag cgtgttccaa gattaaaaac
     9481 aacttgtttt tataaaattt atagaaaaac acacgaatga ttttacaaaa aagatgccaa
     9541 cctttttgtt tgaatcaccc gtgtgctgtt tttattatca atctatcttt acttatattg
     9601 ttcctccaaa cggctcatcc accaacctag tgctgtaccg gctataaaaa gaacaggaca
     9661 agctagtacc ccagcaactc ccaatcccgc gtaatcggta ggaatgatca taatcgttga
     9721 agcaaaaact acacctaaaa tgaaatggaa tagcttgcta tatgcctttg agaaaatgta
     9781 atccatgatt tttgacaatc caagaacaca aagaatccca ccaattccga tcggcacaat
     9841 cacttcaagt cgtacttctt taaatccgtc agccatcgct ttatacaatc ccatatacac
     9901 caaaaaatta gaagggctca atcctgggac gatcataccc aaaccaatca atccgccggc
     9961 aatcagccat gttccaaaat tctgatcgac ttgcccgtca aataattgag cgccgtataa
    10021 taaaaacaaa taagccagaa caaaagtaac aaccatgatg atcacatcag aagtatctct
    10081 tccttttttc cctgcttctt tccataacgc aggaacagtt ccagcgatac atccgacaaa
    10141 aaaccataat atcgttgttt catacgcacc taataaaaaa ctgactaaaa aagaaagtag
    10201 aaagatgcct gtcactccgc ctagaccaac aggcagaaaa aacaaaacat tttctttgaa
    10261 attttttgta aggtgggcta aaaaagaaat cagccgctca tacatgccaa agacagctgc
    10321 taatgcacca ccgctgactc ctggcaagat aaatcctgaa ccgataaaca ttcccttcac
    10381 aaaccgtaac atccagtctt tggttgtgta ccccacttct tgattttcca ttttttgcct
    10441 tttttccact atttgcgcac tccttctttc atttaatttt attcatgatt gaacatttcc
    10501 tgctatttta cttaaagact ttttcatagg tctctattat tttttcattc attttgacaa
    10561 tatcaggata aaacatgtta cctccattat gatagagata gccgccattg taaagcaagg
    10621 actggatccg ccaatatcgg tattgtttcc cttcctcatt tcctaaaagt gggctcagca
    10681 catctttaga atacgcttct gctaattcta ctgtgttttc tccgccatga ttttttacat
    10741 aggcaatata atctttccca aaattatatg cttggacagc tgtccataaa tcgcatcctt
    10801 gtttctttgc ttctactatc atttccgcca aatatttgac accttgatca atactgtcag
    10861 ctggattatc aatgatctca gcttctccat gcagactttc cgagctctgc atgagatctg
    10921 tcccttttcc ttttgattcg gtcaatatta tcgccttgat caaattctcg tagttttcca
    10981 tatgataatt ttttgcagct gttgttattt ctatttgata gctttccact cgttttaccg
    11041 aacgataagt tcttcctcat aaaaacaaca ccgcaccaat aaccgtcaga atgatcatgt
    11101 aaaaaagaat acggataata gataatcgtt ttcgcttcat ttcatcacct agttattttg
    11161 acatcttttt ttatcttact atttctttat cttcttggct atttcttcct tgatttctgt
    11221 gtacgcctta agaaaaaatg aattttcctg tattttttga catcttacga aaatgatcgt
    11281 tgtttttcag taaaaacaat tgcccaatga ctgatataat cgttatactt tacacagtag
    11341 gtgattatgt gaaaaaagaa aagaaatatg caaaaatgcc agatgggagc gaaatttact
    11401 atgaaaagag cggtcaaggc ttccctctct ttttactgca tggcaatgac ggcagcggcc
    11461 gctttttttc agaacaggtc cctgtactcg aacgctacta taccgtgtat ctagtagata
    11521 gccgaggaca tggtcgttcg acaaacgaag catctatgtt gaattttcag ttaatggccg
    11581 aggatctgaa tacgatcatg ttgctggaaa aaatcgatca ggcagatttt cttggattta
    11641 gtgatggagc aaatctagca ctggtatttg ccagcagctt ccctaaaaaa gttcatcgat
    11701 tgattttaaa ttctggaaac acgcttgtta aaggcgttcg tttttctgcc agagtcatca
    11761 gtaatattca ttatgcatgg gtatggttac tctctttatt tcgcccaagt cttcgcaaaa
    11821 atcttttagt tatcaaactt ttgctgcatg acatcgggct tacagaaaat gatttaaaaa
    11881 aaatcaactc ccccactttg atcatcgtgg gaaaaaaaga tgtaatcaag ctaaaacatt
    11941 ctttgtatat agctaaaact ataccaaaag cttcctttgt gcttgtgaaa gaacaaggac
    12001 atgaattagc tagaaaagat cctgaacgct tcaatcgaga agttcttcaa tttctttctg
    12061 aaacataact attaggaata gaaggtgatt tatttgttaa aaaataccat acaatggctg
    12121 aaaaaccacc taggactgtt caaaacaatc tttttgattt ctgtcattgt cattattgtc
    12181 ggtgaattga tgtccatcgg taaaactcta tctatccagc aattaggaga aacgtttgcc
    12241 actatacctg tatggaaaag cggactaatg ctattgattg gtcttatctc tgtgttacct
    12301 atggttggtt atgatattat tttgaatcgg atgcttgaac aaaagcagaa tcctcgttac
    12361 ctgtttgaga caagctggct gatcaatacg atcaacaata ttgccggttt cggcgggttt
    12421 gttagtgtgg ggcttcgctc tgaactatat ggacaaaaga aagagagcag aaacgtgatc
    12481 caagcattat cgaaagtttt cttgtttttg atggctggac tttctattta cagtctgctt
    12541 tcttttttac ttgtagtctt cacgccagtt gctccttttt tgaagcaata ttggatatgg
    12601 ttgatcggcg gcggtctata ttttcctgtc gtctttttat ttactacttt caaaaagaaa
    12661 ggattccttg gtggtacctc acttaaaact caaggacagc tattgctagt ttcattgttg
    12721 gaatggaccg gtgtcctgtt tagtttcctt tctgttggtt atttaatgga aatccggatt
    12781 gatctgtggc aaacaattcc attattcatt gctgcttcag tgataggaat cgtgtctatg
    12841 attccaggag aaattgggag tttcgatgta atgatgatta tcgggttgtc cgctattggt
    12901 gtgccaagag aaatagtcgt tgtgtggatc ttgctctatc gcctgttcta ctacatcatt
    12961 ccgtttttga ttggaatcgt ctttttcttc aaaaatatcg gttccacttt tgatcagcgt
    13021 tattctggta tccctaaaca attagcaaca gaaattgcgc ataaaatcgt ggttgtctta
    13081 ttatactttt ctggaatcat gctagtactt tctgccacta tcccgcaagc ttttacagag
    13141 tttcgctggc ttcatagttt gaacccattg aaatttcatt ttattatcca atttcctagt
    13201 atactattgg gatttctttt aatcattatg ggcagaggga tcgcagcacg tgtgaaacga
    13261 gcatatttgc ctacaatctt cttgattgtt ctagctttac tttatgtttt attaagtgat
    13321 tttagtttca caccggtggt tttcttgtct attctgcttc tgatcattct tgcttctaaa
    13381 aacgaattat ttcgggaaca attgatctat tcatgggagt ggcgtacgat cgatggaatc
    13441 attattggtg cactgtcctt gctttacatc gttattgggg tatacaatct gccggatttc
    13501 cctcatcggc gtcaccattt tatttccttt ttcttatttc cttctgaaaa gatttggttt
    13561 tcgggattgt tggccatcat cgctgttagt ttcatgatcg ttctatttgt tcatttcctt
    13621 caaggagaaa agaaacagat tggcgaagcc tttaatgaag aaaaggccct gaagatcctt
    13681 acaacttatg gaggaaactc cgatagtcaa ttgatcttct taaaagataa gcggatgttt
    13741 gcctatgaaa aagacggtga accaactgtt cttctccaat tcgcttgctt caataataaa
    13801 tgtattgtaa tgggtgatcc ttctggtaag aaagaagatt ttccagaagc aatcgaagct
    13861 tttatcgaag aaacagatcg actatgctat ttaccagttt tctacgaaac aagcgaagag
    13921 attgttatga ttttgcatga attcggctac gatttcatta agatggggga agaagcttat
    13981 gtagacctga atagttttac aacttcaggg aaaaaaatga agggcactcg tgctgtcttg
    14041 aatcggatcg aacgagaagg atttacattt gatgtcttac aaccaccatt ttctactgag
    14101 caaatgagta ctttcaaaaa tatctctgat aattggttgg gttcacgaaa ggaaaaaggg
    14161 ttttctttag gctttttctc tgaagattat ctacaaagag cgcctattgc agttgtcaaa
    14221 aatacccaag aagaaattgt cgcttttgca acgatcatgc ctacttacac gaacaataaa
    14281 gtaggaacga ttgatctgat gcgatatgat tctaaaaaag caccttctgg cagtatggat
    14341 ttcttgttct tgcatttgtt tgcctatatg aaagaagaac atatccaatg gttcaattta
    14401 gggatggccc ctctttcaaa tgtcggaact tccagaaaga gttttttaca ggaaaggatt
    14461 gcatacttgg tttacgagtt tggttctcat ttttattctt tccatggatt aagagaatat
    14521 aaaagcaagt acgctacaaa ctgggtctca cgttatactc tatattctag agatagttgg
    14581 attgcatatg ttatgattgc tttgctgatt attgataatg cgccagttga gcagacacaa
    14641 ggtagaataa gtggtttgaa aaaatggata cgaagaaagt attaaaaact gcataccgat
    14701 agatgaacac tctcatgatg aataaaagag actgaagtaa aacgaaagtt catgcttcta
    14761 caatctcttc ttatacaatt gaagaacaaa gagcggtcca aacagaaatc ctgtttggac
    14821 cgctctttta ttttaaacat ttttcattac caaaatattc gagtcgcgtt tcttatgctt
    14881 cgatctctgt aacgatacct gaacctactg tccgtccgcc ttcacgaatt gagaatgtcg
    14941 ttccgttttc aacagcgatt ggatggatca agtcaacatc aatcgtcacg ttgtcaccag
    15001 gcatgaccat ttctgtatct tctggcaatg tgattgttcc tgtaacatca gttgtgcgga
    15061 agtagaactg tggacgatag ttgttgaaga atggagtatg acgtccacct tcttcttttg
    15121 tcaacacgta cacttctgct ttgaattttg tatgtggagt aatggaacct ggtttagcaa
    15181 gtacttgtcc acgttcgata tcgtcacgtt ggatcccccg taacaacacg cctacgttat
    15241 ccccagcttc cccgtaatct aacgttttac ggaacatttc tacacctgtt acaactgctt
    15301 tttgtgtttc aggtttgatc cctacgatct ctacctcatc accgacacga acagcaccac
    15361 gatcaatacg acctgaggca acagttcctc gacctgtaat tgagaagacg tcttccactg
    15421 gcaatagtaa tggtttatct gtatcacgtt ctggtgttgg gatatattca tctactgtat
    15481 ccatcaattc cataatagca gcttcagcat ctggatcgcc ttgcaatgct tttaatgcgg
    15541 aacctttgat cacaggagtg tcatcgcctg ggaaaccata ttcgctcaat aactcgcgaa
    15601 cttccatttc taccaaatcg atcaattctt catcatcgac taaatcaact ttgttcaaga
    15661 aaacaatcag gtattttaca ccaacttggc gtgacaataa aatgtgttca cgtgtttgag
    15721 gcatcggacc gtcagttgca gaaacaacta agattgcacc atccatttgt gctgcccctg
    15781 taatcatgtt tttcacatag tccgcgtgtc ctggtgcatc aatatgcgcg tagtggcgtt
    15841 tttctgtttc atattctacg tgtgcggtat tgatcgtaat cccacgttca cgttcttctg
    15901 gagctgcatc aatactagca tagtcttgag gatttgctag gccttttttg cctaatactg
    15961 tagtgatcgc agcagttaaa gtagttttcc catggtcaac gtgtccaatc gtaccaatgt
    16021 taacgtgtgg tttacttctg tcataatgtt cttttgccat aatttacaaa cctcctaaat
    16081 aatatagatc actgaaaaat ttcagctctc acctttttat tatagtcttt ttttgactaa
    16141 atcaaaaaga atacgtccga cttacttttt gtaagattcg aactaagctt attatacgtc
    16201 aatattggtc aaagtcaact aagagcactc gtctgtctta tacgcgaaaa aagtaccttt
    16261 tataaataaa aaaatgtgtt ttttgagaaa aacttcaaga tagtccttaa ctttcttttg
    16321 aagcaataag aacaaaatga ggaaaagttt aaaattcagc tgttgccaac aactttcaat
    16381 agacgaaatc ttctatttcg ttaataataa ggaaagaggt gaagtacatg aaaaaattaa
    16441 ttggcgtact tgtcgtttta ggcatatttc tcggcggaag ttttgcagct tatcattatt
    16501 tttacggcgg cgaagcttat tatacaaaaa tcacgacgaa tggcgaaatg tcagctaccc
    16561 aagcagataa cggagagaaa ttcacgactt atacctacaa gcaagcggct tataataaag
    16621 atggtgaaaa aaaacaggtg acgcttcgcg aagaaagaga acatccatta aagatgaatg
    16681 cgtatcttaa actcaaagtc aatcctcgta aaggtgtatt aagctgggaa gaaataaagg
    16741 cttctgaagt gcctaaaaat gcggcagaaa aaatcgataa ttagtaaatg gtcttaaaat
    16801 tttattagat aaaa
//
LOCUS       DAJSMK010000049        16529 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.051, whole genome shotgun sequence.
ACCESSION   DAJSMK010000049 DAJSMK010000000
VERSION     DAJSMK010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.051"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(141..416)
                     /locus_tag="ON488_001676"
     CDS             complement(141..416)
                     /locus_tag="ON488_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HCR3231872.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(659..1969)
                     /gene="der"
                     /locus_tag="ON488_001677"
     CDS             complement(659..1969)
                     /gene="der"
                     /locus_tag="ON488_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HCR3231873.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="ON488_001678"
     CDS             complement(2151..3380)
                     /gene="rpsA"
                     /locus_tag="ON488_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HCR3231874.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3515..4195)
                     /locus_tag="ON488_001679"
     CDS             complement(3515..4195)
                     /locus_tag="ON488_001679"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HCR3231875.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4244..4879)
                     /locus_tag="ON488_001680"
     CDS             complement(4244..4879)
                     /locus_tag="ON488_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCR3231876.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4945..6348)
                     /locus_tag="ON488_001681"
     CDS             complement(4945..6348)
                     /locus_tag="ON488_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HCR3231877.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6335..7366)
                     /locus_tag="ON488_001682"
     CDS             complement(6335..7366)
                     /locus_tag="ON488_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3231878.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7397..7618
                     /locus_tag="ON488_001683"
     CDS             7397..7618
                     /locus_tag="ON488_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HCR3231879.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7783..8520)
                     /locus_tag="ON488_001684"
     CDS             complement(7783..8520)
                     /locus_tag="ON488_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HCR3231880.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8673..10013)
                     /locus_tag="ON488_001685"
     CDS             complement(8673..10013)
                     /locus_tag="ON488_001685"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HCR3231881.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10250..11773)
                     /locus_tag="ON488_001686"
     CDS             complement(10250..11773)
                     /locus_tag="ON488_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HCR3231882.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12151..12762)
                     /locus_tag="ON488_001687"
     CDS             complement(12151..12762)
                     /locus_tag="ON488_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCR3231883.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12885..13010)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13092..13808)
                     /locus_tag="ON488_001688"
     CDS             complement(13092..13808)
                     /locus_tag="ON488_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HCR3231884.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="ON488_001689"
     CDS             complement(13814..14383)
                     /gene="scpB"
                     /locus_tag="ON488_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HCR3231885.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14367..15164)
                     /locus_tag="ON488_001690"
     CDS             complement(14367..15164)
                     /locus_tag="ON488_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HCR3231886.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15134..15505)
                     /locus_tag="ON488_001691"
     CDS             complement(15134..15505)
                     /locus_tag="ON488_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCR3231887.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="ON488_001692"
     CDS             complement(15524..16411)
                     /gene="xerD"
                     /locus_tag="ON488_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HCR3231888.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4646 a         3577 c         2797 g         5509 t
ORIGIN      
        1 aaaaattaaa taaaatacat gtgttttcta tgtatgacat acggattcgg aatctctgtc
       61 tcttatttat tccttttctg ctaggaaata aaaagaaaag cacttgtagc cctagagcca
      121 caagcgcttt ttcaactgtc ttatttaaca gcgtctttta atgctttacc tggtttgaat
      181 gcaggtactt tgctagctgg aatttcgatt tcttcaccag tttgtgggtt acgacctttg
      241 cgagctgcgc gttcgcgaac ttcaaagtta ccaaaaccga ttaattgaac tttttcgccg
      301 ttagctaaag catcttgaat agttgaaaat acagcatcta ctgctgcagt tgcatctttt
      361 ttagttaaat cagtagctga agcaactttt tcgattaatt ctgctttgtt tgccatggat
      421 agattcacct cctccacaag agatatgata gaaatatcat ttagttaaaa ctttctgagt
      481 ggtccagaag tttaaaaaga aatattgatt aacttcaata ttctgttatc acgatatcat
      541 atgaaccgct taatagcaag gtttttacca attttcacat gcttttttta gtcatagaaa
      601 cgtaacaaac gaaactgtct ttttcttttg aaaaaaaaac gtcgatatgg taaaatgcct
      661 attttctcct acgagggata attcggatgg acgtcccttc aaaagtaaat gcttttctga
      721 tttgattttc taagaaacgt tcataagaaa aatgcatcaa ttcctcttca ttgacaaaaa
      781 cgacaaatgt aggtggtttg acagcgactt gtgtagcata aaaaatcttc aggcgttttc
      841 ctttatctgt tggtgttgga ttgattgcta cagcatccat aatgatatca ttcaacacag
      901 ccgaagagat acgaagattc tggttcatac ttacttgttc gatcatttca ggcagacgtt
      961 ccaaccgttg tttagtcact gcagaaacaa aaacgattgg agcgtaatca agataccgga
     1021 attcatcacg aatctcttgt tcgaaatcac gcattgtatt ggtttctttc tttacaagat
     1081 cccatttatt cacgacgata ataattccac gaccagcttc atgggcgtaa cccgctactc
     1141 gcttgtcttg ttcccgaatc ccttcttcag cattcagtac catcaaaacg atatcagaac
     1201 ggtcaatggc acgcattgca cgcatcacgc tgtatttttc agtattttcg tatacttttc
     1261 cgcgtttacg cataccagct gtatctatca ttaagaattt ctgaccactt tcagaaacga
     1321 agtgggtgtc gattgcgtct cgggtcgttc cttcaatatc cgaaacaatt acacgttctt
     1381 ctcctaaaat cgcattgatc aaagaggatt taccaacatt tgggcgacca atcaaactaa
     1441 acttaatcgt gtcgtcgtcc tcttcttcag tctcttcaga gaaatacttc actgcttcat
     1501 ctaaaatatc accaatccct agtccatggc ttcctgaaac aggataagga tcgcctagcc
     1561 ctaaggaata aaattcatag atatcgtttc tcatttctgg attatctact ttattgactg
     1621 ctaaaatcac tggtttatta cttctgtata aaattttcgc aaccatctca tctgcgtctg
     1681 tcacgccttc gcgtccgctg actacacaaa tgattacatc tgcttcttca atcgcgattt
     1741 ctgcttgatg cttgatctga tccataaaag gttcatcgcc aagatcaatt ccgcctgtgt
     1801 cgatcacgct gaattctcga cctaaccatt caccttttgc ataaatacga tcacgagtta
     1861 ctccaggagt atcttcgaca atcgagatac gctcaccagc gatgcggtta aaaatcgtag
     1921 acttaccgac gttcgggcgg ccaacgattg caattgttgg atttgccata ttatttcctc
     1981 ctcacaagtt tccaatctca cttagtttaa cgaatgcatt gccaactttc aagcatagat
     2041 tgtcaattaa acgaagtatt tttattcctt attgaaatac taatcgcttt tcaaaagaaa
     2101 aactgagaca aaagcagctg ctttcatctc agtcacagat acaaaatcaa ttatttttca
     2161 gaatcatcgg ttgctttttc ttctacttct tctttcaacg catcacctaa aatgtctccc
     2221 atagtaaatc cagtattttc ttctggtaat tcataagact caacattttt tggttcttct
     2281 tctgaagctg gtttttcttc taaagctttg atactcaatg caatacgatg ttcttctgga
     2341 tggatctcta atactttcac tttcacttcg tcaccttcat gaagcacttc atgtggtgtc
     2401 gcaatatgtt tatgtgaaat ttgagagata tggactagcc cttctactcc agggaacact
     2461 tcaacaaagg caccgaagct tgtcaaacgt ttaactgttc cgtctaatac tgtgccaact
     2521 ggagcttttg tatcgatttc tgaccaaggt ccaggctgtg tgtctttgat tgacaaggaa
     2581 acacgttctt gttcaggatt gatagacaac actttgacat ttacatcatc attgacagcc
     2641 aatacatcac ttggttttgc tacatgacta tgtgaaatct ctgagacatg gactagaccg
     2701 tcaattccgc ctaggtcgac aaatgcgcca aaatcagtaa gacgtgcaac acgtccactg
     2761 agaacatctc cctcatggat agttgaaaga atttcttttt tcttttcttc tctttcgttt
     2821 tccactaccg ctttatgcga taagatcaaa cgattttctg atggttcgat ttcgatgatt
     2881 ttaaagctca atgttttgcc tttatagtct gaaaagtctg caacaaaatg atcttccacc
     2941 attgatgcag ggacaaaacc acgtacaccg acgtcaacga ctaaaccgcc tttgacaaca
     3001 tttgtaacag gtgcttcgat gaccttgccc tcttggaaat ctctttcgat atcttcccaa
     3061 acttttttag catctaaacg gcgttttgaa agtaggtagc tgccgttttc tttatctttg
     3121 ccgatcgtac tgataacgac taaatctaat acatcaccga cttttactac ttcgctgata
     3181 tcttctaccg gcaaagttga taattctttt gccggaacga ctccttcaac tccagcccct
     3241 tcgattccga caatcacttg tttgtcttca atgactaaaa cttcgccctt aacaacatcg
     3301 ccaactttta cttcttgtac gcttttcatt gcgtcttcca ttgactggtt gttctcttga
     3361 ttttgatcaa attctgtcat aacacttgtc ctcctaacca acattctgcc gtaagtacgg
     3421 tactgttttt agtttaattg attattcaaa aaaaataaag cgatttcgtt cgttttcctt
     3481 gaaaaaacaa ttgtttttca ttttttttct taatttaaaa aagaagataa ccttttttca
     3541 aaacaacagc ttttattgct gcaacgactt ctggaatcga tttgccagtc gtatcgatac
     3601 gaacagcatc ctctgcttgc ttcagcggag agacgtccct tgttgaatca taatggtctc
     3661 tttcctgtat ctctttcgtc agtgtttcaa gatcagtcgg aattcctttt tcttggttct
     3721 ctttgaaacg tctttctgca cgctcactta cgcttgctac taaaaagatt ttcacttctg
     3781 cattcggtaa tacagctgtc ccgatgtctc ttccgtccat gacaacgcca ccgcgttccc
     3841 ctatttttcg ttggacagca actaattctt ctctgacttt tccatgtgca gagacttcag
     3901 aaacagcttt tgtgacatct ggttgacgga tttctaaagt cacatctttt gatgctatga
     3961 atacatgctg tccatcttct tgttgcgaaa aagagatagg atactttttg atcagcgaaa
     4021 ctagcccttc ttcatctgaa aaagatacat tgttcgtaat agctaaataa gttactgcgc
     4081 gatacatggc accggtatct gtataaatat aattcaattc ttttgctaat atcttggcaa
     4141 cggtactttt cccagatgaa gcaggcccgt cgattgcaat actgatttgt gtcatgatat
     4201 aactcctttt tctcagaaaa aaagccgcaa agcgcggcta ttattattta attcttaatt
     4261 cttgaccagg gtaaagcata aagttgtttg gatctaagcc attcaattca aacaattgat
     4321 cagtggtgat ccctgcacgc tcagccactt gttttggacc ttcgcctgct tgaacagtcg
     4381 ttgttgaacc ggctgcagct gatgaagaag gtgttgtttc tgctgcattg ctgcttgaat
     4441 cccctgcttg ataagttgcc tcacttgagg aagtcggtgt tgtctctgct gcaatactgc
     4501 tttctgacgt tacacctgta tcttgagaca cagtagattc ttccgcgatt gtactagatt
     4561 ctactgttga agtctcagtt gactcctctt ttgttgtact tgtagaactt tctactactg
     4621 atgtcgaagt ttcagaagaa gttgctgctg ttgcattgtt gcttgatcca tttctgatcc
     4681 agaaataagc acctgctgga atagcgatac ataagaccag taaaatcaaa aatagcgaaa
     4741 gaaataatgt atttcctttc ttttgttgtc tctgagaact tcttgatgaa acttcatcat
     4801 ctgtatcgta gattggttgt tcccatggtt cttgtgtttc gttattttct gtagattgat
     4861 gtctatcttt tctgctcact gttttacctc ctaaactcta tcgtgtgtat tataccatag
     4921 gaaaaagtgt cttgtcctaa aaaatcaatg ttccatgttt tttttaaata aatttagtaa
     4981 aatcgtttcc caatgaagtt gttcagtctt agaaaaaagc ttcctctttg gcagaagttc
     5041 tgcttttgct ccatcaatat cacaacaatt ctgcggcttt tcggagagtt tttcgccaaa
     5101 ataagctaag atgaattttc tgcggcagtt ttcttcatta atatagcgaa gcatctgctg
     5161 caggcggaat tctttttctt tttcctgacg tttgagccgt tccacccaat tttctggttt
     5221 ttcagactgc tggatcagct ccatccattt tttttgcagc tcatcaaagg gagcttgctt
     5281 tgtggcatat tccaaataaa gctcaaaact ttgtcgctgt tctctagaaa gttgattaaa
     5341 gaaataatgg atacgttcat ccccactttg ataaaaaaga attgctgcac tttcttcctg
     5401 atctctgcct gctcgaccga tttcttgtac atagttttct agactgtctg gcaaatcata
     5461 atggaccaca taacggatat cagatttatc gatccccata ccaaatgcat tcgtagcaat
     5521 gagaaactgc agctgatttt ttacaaactg ctgttgaagt tgtcttcttt gagctgcatc
     5581 aagaccaccg tgatagtatc caactgtaaa acgttccctg aataaatgat acaatcgttc
     5641 gacttctttt tttgttgcac aataaatgat tgccgctcct tgtgctcttt ccatgaagtg
     5701 ttcaagttct tgttcttttt gctgcgtttt ccgaacaaaa agcgagatat tttgccgatt
     5761 gactgattgt ctgatctctt ttggtggtcg atcaaatagt acatgacgta tatctcttgc
     5821 tactaaatct gttgctgtcg ccgttagtgc cagtgtgacc gggtttccta aaagctttcg
     5881 gatttttcct aactgttgat attctggacg gaaatcaact ccccattgag acacgcaatg
     5941 agcctcatct actacatata acgcaatatt ttgttttttc agatgctcta aaagagaagg
     6001 attagtcaac atttcgggac tcaaaaacaa aaatttatat tgcgatagat gacggaggac
     6061 gtatcttctt tcagattgcg aaagtaaact attgaaagca gctactcgtt tctcccctcg
     6121 tttttgtaat tgcgtcactt gatcttccat tagagaaagc agcggtgaca cgatgatgac
     6181 cagaccttcc attaaatacc ccgtcaattg atagcaaagg ctttttcccg ttcctgtagg
     6241 caaaatagcg agagtatctt ctccatcaag caacgcctga ataatttctt cttggccggg
     6301 acgaaatgaa tcaaatccaa aatatttttt taattcattt attaacattc tgtatcgctt
     6361 cctttctcaa tagatagatt tgatacaaac gaaattctcc ataatctaat tgtccatcta
     6421 cattccattc gctaaagcgc cactctcgca cggaatcctt atttggttcc aaacgttcga
     6481 ttgtttctgc agagagaatc cactcgtatg gaaaatcatc aaaaaacaag gcccactcaa
     6541 taagatgatc tgttactgtt cctcttttta aatgacggat tgccatgatc tggtcaattg
     6601 tctgaccatt cataaacatc tgcttggtga tcatcatgct ttgattgaaa ttttgctgta
     6661 ataatgaatc gatcaaagcg tgccaaagcg aatctggccg tttttcgatt tgtgctaaca
     6721 aaaggtggat acatctgctt tgttgcagat aaacctctga ctcatcattg ttttttgcca
     6781 gctgataagg aagcagccct gttcgctcat ttccagataa ttggttagct aaaaaatctg
     6841 ctgcttcttc tggtatctcc gaaaacagct gcaccaaact ctcatacgca gtatcaatca
     6901 aaatttcacg tggcaattgg ctttcactaa gccatttttt tagttggaaa gtataaaaag
     6961 gacttgtctc tgctggaaga tagtcttgaa tacccgttgc cagattagaa attacttgaa
     7021 cagcaaattt aatgagccgc caactagttt cccctgttct gccatagcgg tcaaaacgca
     7081 aaccagtatg ttctatttga tgttcggaca acatatcagc ccctgcaggc gttagctttg
     7141 cttcattttc atttatttcg atccaacctt gctgcgcaat tttttgcaaa atttgataaa
     7201 acttatcctg cttcaattct ggaaaactgt tatggataaa caaaagttcg tgggtaaatc
     7261 cataaataag tactgaagtc gttcgttttc ccacaaggag ttggtaaaga gaactaatcc
     7321 gcagcttgtg tcctgatgaa aatagcgata aaataaaaac aatcatatta ttctccttaa
     7381 gttaggatgg ttagaaatgt cactactatg taaacttgta cctgaacgct gtattgcatg
     7441 cggtctttgt caaatcgaag cgccagatat tttcgattat gatgaagaag gaatcgtttt
     7501 atttgcccaa gaaccagagg ctcatcaaca gttcgtgatg ccggaagaag aaacatatgt
     7561 aaaaaaagcg tatcaaaaat gtccagttcg agcgatttta ttagaaaata aaatataaat
     7621 ataaacgaaa ctttaaaaac gtacactaag ttctctaaac ttgaaaataa gccgggatct
     7681 gtttctcttg ttccgtgaaa tcccgactta ttttgaaaga ttcatttgct atctatagtt
     7741 aattgactag ttttttcacg gaccctatag gacccattta tattatttca actttttcag
     7801 ccagttttcc aatgtattga cgatcacagt ttgctggtct gcgttagaaa tttctgcctc
     7861 tccatctcct ttttgctcac catagctgcc aaaacctcca tgatttccgc cattgattga
     7921 tacatactct gttctttccg gtaaatactg cttagcttct tgataagctt cctgattcaa
     7981 tactttatct tttgtcgccg tgatcgataa aacaggaaca gctgattctg tcaatgttcc
     8041 ttttttgtcg ggataacttg ccatgaagaa tacccctttt aaatgtttgt ctgaatgatt
     8101 cttattgaca taacgacttg ccattacgcc acctaatgaa tggccaccga tcacataatc
     8161 ggaatttgga aaatcttctt tgaccttatc cgctttgttt ccgcccatca ctgctagatc
     8221 aagtggcatt ttgacaatag cgactgaaaa gccgtttttt gctaaatctt gcgcccaaat
     8281 actataactt tctggctcta cgagagcacc aggataaaaa ataagtaatg gagactttcc
     8341 atgattcttt ttctctcctt caaaaaataa gtaatcttct ttgttttttc cttcttttac
     8401 caacacttgc gcttctgacg atggttcgta cgtattttgc tgtatatagt aataaccggc
     8461 tccaccgagt aatcctaaaa tgatgactaa gccaattagt attcgtctaa atattttcac
     8521 tttctcccac cttttctatc tgagtgaccc ctttttctta atcaagtatg attatacctt
     8581 aaaaaaataa gaaagaaatg caaactttcc agcatcaaat aaaaaaagac ggaatatcca
     8641 tttgaatatc cgcccttttt gtatgtttat ttttatttag cacataaacg atacacagct
     8701 tctgcataaa tttccattgc tttatacata ctacttaatt cccatcgttc attcgcctgg
     8761 tgcataaagt caggagtatc agggaacatc gcaccgaatg ccacacactg gttcatcgta
     8821 cgagcaaaag tagcgccgcc tgatacaaac ggttcagtca tgtctccagt aatatcgcga
     8881 tatgtcccca atagattttt cactaactca ctgtctagtg gcacgtataa tgaatcaagg
     8941 aagtcaaatt cttcataagt caacccatat ttttctgctg ttttagttaa tttagctact
     9001 aaatcatctt tcttgaatgt aacagggatt ctcatatcta caccgatttt tgtttgttct
     9061 ggtgtgattt ccaaacttgc aaagttcatc gttagctcgc cggattgttc atcttctgtt
     9121 ttgcccacga cagcttcacc agttgcattt tcttgaacta attttcctaa gaaattgatt
     9181 gggccaaaat caaatacttc tgaaagagca attgccagac gagaaatagc attcactcct
     9241 tgtgctgcat ctttcgcgtg gatactttta ccaagaacga cgatgccttc accttgttct
     9301 tcgaaatcga attcgtgttt tttcaatgct tcttttactt cagaaagctt ttctccagag
     9361 taaggagctg catcaggaac aacattcaac gctcctccag cttttacaga aaactcgttc
     9421 gttcctggtc ctgtcaagta agcttgcaat aagccttttt ctgcataaat taaaggaaat
     9481 tcagcatctg gcgcaaatcc ttgcgtaatt ccttcttctt tttcgttata tttttctaaa
     9541 caacgccata aattttcttc atctgtacca aagataaaac gaatacgtgt cttgaattcc
     9601 acgccagcat caatcaaagc tttgacggca tacattgccg caatagaagg acctttgtca
     9661 tcttgggatc cgcgaccaac taaccagccg tcttttatag ttggatcgaa tggttttgtt
     9721 tcccaattat tttcgtcccc tgctggaaca acgtccatat gacacaagat accgaataat
     9781 tcatctccag agccaatctc tgaataaccg taatagcctt ctggatcttt aaatgttcta
     9841 aatcctagct tttcactgat ttccaatact ttatccaaag cttcaatcac ttttttaccg
     9901 aagggatgtc cttgtcctga atctgcttca tctagtacgg aaggaattcg gatcaattcg
     9961 ctcaatgatt ctaatgcttg ttcatgatgt tgttctgtca caaatttttt catgatatta
    10021 tcctcctaat atgttaaaaa gggtcatgtc aaattcctcc gacacaacct cttcttctca
    10081 aataatgacg ttttaagcct gctccatcag caagcagaat gttcttaaca aatgatgaaa
    10141 gaaaaaacac tcactgaatg gagctattga cttgtccacg tgcttatcga tagccgttta
    10201 tcggtttctt cattcttatg atagaccttg tacctgtatt tgtctaggtt tagaacattg
    10261 ctgctacacc taggatcaca cagatggcta caaataatat cgcaattaat ttaccggtaa
    10321 atttccacca cactgaaaca tcgaaacgag caattgctac agcacccatt acgatagcag
    10381 atgttggtgt aattaagttt actaaaccag atgcagattg ataagcagtg attactaaat
    10441 ccttaccgac gccggcaaat tcacccatag gtcccatgat tcccattgtt gcagcagcta
    10501 agccggaagt tgaaggaatc aagaatgaca tagggatata gaaaataaat gtaataatga
    10561 tgaatacact tgaagataat gaacttaatc cttgttcgcc ccaatgtaag atggtgtctg
    10621 tgattaatcc attgttcata accacttgga taccacgagc aacagctact acgattgcta
    10681 caccgatcaa atcagaagca ccagctaaaa attcagagac aaattcagac tctttcatgc
    10741 cataagtgat tgctactacg atggacatta ctaagaataa catagtaatt tctgggaagt
    10801 accagtcacc taatggaagc atgcttttac ctagaaccgt acctagtacc ggaaggtttg
    10861 ttaaccagtt tgtcaatgat tcaaaaatcg tgaaattcgc attcaaggtt gtccaaggaa
    10921 tcaaactgat gatcatgata ccaaaagtaa taaagaacaa tacattaaca tgtttttgtt
    10981 ttttcgtgat tacttcttga cgaccgattg cttcaatatc gaaatgcttc atatcttctt
    11041 tacgttggtt gtatactaat gattttgttg gatctttttc gatctttgat gcataacgat
    11101 acacatatac aatagaaata gctaacaaaa taacgaacat caagaatcga agaccaatac
    11161 cttcacccat cgaaatccca acagcttgtg aagctacgcc tgttgcaaaa ggatttaccg
    11221 ttgaagctag acagcctact tgagacccta ctaatacgat tgctacagct actactgtat
    11281 caaagcctac agccatcatg actgggatca gtaaagcata gaatggaatc gtttcttctg
    11341 ccattccgta agtagagccg cctaatgcaa ataacagcat caatactgga ataagcattt
    11401 tttcttttcc tttgaatttc ttcacaactg aagcaatccc ggcatctagt gcccctgttt
    11461 tgttgataat acctaaaaat ccaccaacaa ccaaaatgaa gaaagagatt gggattgcag
    11521 caggtgtttc tttagttagc tcccccgctg gtacacctag catcccattg attggcgcca
    11581 tgaaaatatc ccacagccct tgaggatttt gttgtactcg ttcatatgat ccagcgacga
    11641 tgttgcctgc atcgtctaca ctatagtgcc cagctggtat aaaccaagta agtacagcga
    11701 ttactgcaat aataataaat aagaccgtat acgctgaagg catttgaaat tttttctttt
    11761 ttgtttgttc catcttcttc ttcctttctt ttccgttaga gacaacaatt ttggctctaa
    11821 tgttatttta tcaaaaagag tatcagaaca aaaataataa cacgcatttt gtaaaacttt
    11881 tgttcaaaaa gttcgttttt ccctattccc tcctcttttt tcaggttttt aaagctttct
    11941 tctttttcat tgtagcgttt cctttttttt ataaacaaac attttcgtct tttaaaagga
    12001 gaagaatttc acatttgcaa agaattgatt gatttttatg cataaatcaa aaaaatactc
    12061 aaaacaaaca aataaaacgt ttacattatt gcatgtcttg tatttttttc caaaaaaaaa
    12121 gaccaagaaa tttcttgatc tttttgatat ttatttgact gctgtatgac gttgttcgaa
    12181 ctgatgttgt tttcgactta accatggaag aagttgcgca tgcagcacta aaaagacagc
    12241 actcacgatg aatcctttga tcaagttgaa aggaacgatc ccaatcagta catagtttgc
    12301 taaagacatg cccagcatct gtgttgcgtt cagccctaaa aacattaagt aaagaggcgt
    12361 aataacgaaa taatttgcga tactcataaa aatagttaga gcgatggttc ctgtaatgac
    12421 acctaaaaat ttgtttcttc ctttatgctg tttctttaca ctaaagaaat aataaatcgg
    12481 gaatgtaaag atcgttgttg ataagaaact agcagtgtct cctaccaaat tatccggaga
    12541 aaaacctgta gtcagcagat gtaatactga acgcaagaac gctgttgcaa ctccggccgc
    12601 tggaccgaat aagaacatgc tgatcaatac cgagatatca ctaaaatcga tcttcaaaaa
    12661 actaaaagcc ggcatgatcg gaaaagcaaa atactgtaaa actaatgcga tcgcagcaaa
    12721 catcgctact gcaaccattt tctgtacacg ggtgttcttc atttgaaatc ctcctgttag
    12781 gactcctctt cagcgaactt tttgacgttt ctctccaaat gaaaaaactc tattttccag
    12841 ggaaaataga gttagagtta tttgatcaag cgtcgtcaaa taagctctat cttctttatc
    12901 cagactatac tgtcggtatc ggaatttcac cgattcagct atttttttgc aaaataggtc
    12961 gtggactata accaccggtc gggaatttca ccctgcccct gaagacgaac cttatataat
    13021 ttttgtttac atattcatta tacatatcta ttcaaaaaac gcaacatcta acacttataa
    13081 aaagtaagtg ttcattttga gtggttcagc aaactgctga cttctttttt gttcagttca
    13141 cggtaatccc caggacgtag gccttgtaaa gtcagatctc cgtatttttc acgttttagt
    13201 ttttgcacag gaagaccaac tgcttgaagc atatttttca cttgatgatt acgtccttcg
    13261 tggatcgtca attccacgat actgtggttt gtcttaggat ccactgataa aatttggaat
    13321 ttagctggag atgtttttcg tccttcgatc tttattcctt ttgtcaaagg tgcaagcatc
    13381 gattttgtag cgatcccttt tacctttgca acgtaaactt tatccacttc atgttttgga
    13441 tgtgtcaggc gctgagcaaa atctccatca tttgtcagta gcaagatccc cgaagtatcg
    13501 taatccagtc gacctacagg atagatacgt tcttttacca tcggcaaaag atccgtaaca
    13561 acttttcttc ctttgtcatc tgcaacagca gaaataactc ctttaggttt gtacaataaa
    13621 tagtaaccgt attcttcttg ataaattggg acttcatcca cttccacagt gtcatgtttc
    13681 ccaactttta tccctaattc ccttacaact tgtccgttta cttttacacg tcctgcaagg
    13741 atgaattctt ctgcttttcg acgagaagtg atgccagcgt gggcaattac tttctgcaat
    13801 ctctccatta caattattct cctttattca ttccatcaaa gaatagatct ggtgacacgt
    13861 cttcttcaag tgaaatttcc atttcttgtg tatcaggcag ttcttctaat gatttcaaac
    13921 caaaataatc taagaagtag ccagttgttc catataatat cggccgacct ggtccttcta
    13981 ctctaccttt ttcttcaatc agtttatggg cagctagacg ctgtaccgct cctgaaacct
    14041 gaactcctcg aatctgctcg atttcagctc ttgtgattgg ctgtttataa gcgatgattg
    14101 ctaaggtttc gacggcggct tgagataatg tgtttgatgt cccttgcgca tatcgcttaa
    14161 gtaagggagc cagctctttt ttagtcgtta atacataatg gctttccgtt tcaaaaatat
    14221 gcaaagctga gtgcgagttt tgagtgtaag attcttttaa ttctttcact aaacttgtga
    14281 cttctgcttc gctgagattt aacagtccgc ttaattcttc attactgatc ccttcctcgc
    14341 caacaataaa aagaagggct tcaagttcac ttaatttcgt catgttcggt atctcctact
    14401 gctggataaa gcataattga ttcatagttt tctttttgtt gcgcaatgat ctgccctttt
    14461 ttcatcaatt ctagcaaagc cataaaagta gtgacaactt cacttttaga aggtgactca
    14521 aaaaaagaat cgaaagtaca gccatgcgca tttcttttta tacgctcttc gataaatacc
    14581 attcgttctt cgatcgttgt gtcatcgggc gtgatcgttt tttccacttt ttgagaaaat
    14641 ttcttacgtt ctaagatttt ctgcatggca cggatcaaat cgattttttt gacttgtcct
    14701 cgcttcaacg gcttttcagc atccgctaac ccatcgatgt tcataggttc ttttgtgtaa
    14761 taaagacttc gttcctctgc tttttctgtc agtctttcag ctgcatattt atatttacgg
    14821 tattctaaaa gctgagtgac caattcttct cgaggatctt cttcccataa ttcttcatcg
    14881 tctgtgccga attcttggac aggaagcaat gtcttgcttt tgattgccat caatgtagca
    14941 gccatcacta agtattctcc tgcaacagct agctcgagtg ttttcattgt atggatataa
    15001 ttcatatatt gctccgtgat cgtagcgatc ggtatatcat atatatcgat ttccatttgc
    15061 tgaatcagat gaagcagcag atcgagagga ccctcgaata catctaattt aatattgatc
    15121 tccgtcaact cattcactct ttcttctttt tctttgctag ccattttcca atgtaaggct
    15181 ctgtgatttc agttgcacgg atggagacat ccgggtactt ttcctgtaat tcatctaaca
    15241 tttgaaagcc catattctca ccgcgataag acggattcaa agaaatgtca tggatgatca
    15301 gctgatcgtt cgttgcccag taaataccaa taatcccttg aatgttggtt gaaccttctg
    15361 gcgtaaagaa aaaaagttca taatcgtctt cagattcgta cgtatcaatc tccttcaaca
    15421 aagaagtttt acctgtcagt ttcttatgga aactcaatag tcccatagca attttacggt
    15481 tttctttccg gtaatgtgtt aacatcttct caccttccta tgactaagcc cttggaaaat
    15541 gctgcttata aacatccgtc attcttttct tcgtgatatg tgtataaatc tgagtcgtag
    15601 agatatccgc gtgacctaac aattcctgta ctgtccgcaa atcagctcca ttttctagca
    15661 gatgtgtggc aaagctatgc cgcagcgtat gtggtgttac ttctttgtaa atcccagcct
    15721 ctcgtactaa ctgcttcaga tttttccaga ttccttgccg agaaagacct ttcccatgat
    15781 tattgacaaa tacatgcatt tcagatgcgt cctttacaag taatggacgt gcttcgtcta
    15841 agtagcgttc cagccattgg atcgcataat cacctaaagg aatgatccgc tctttatctc
    15901 cttttccaac tgtctgtacc agtccaagag aaagatgaag atctcccaat ttcaatccaa
    15961 tcaattcact gacgcgcatc ccagtagcat acatgacttc caagattgca cgatctctta
    16021 tccctaacgt ttttgtcgta tcaggtgctt caatcagctt ttctacttct gtcagagtca
    16081 atgtacttgg taatttctgt gctttcttcg gcgtatcgat atgttgcatc ggatcatgat
    16141 cagtgatacg ctcttgccgt aaaaactgat ggaatcttct gagacttgag atcatccgag
    16201 taacagttgc tgtcgctttt ttttcttcat gcaacttctc cagaaaacgg atgactaaaa
    16261 agcgatcgac atcctgccat gaagcaattt tctgctcctg tagaaaatgc aagtactgtt
    16321 ccaaatcacg ttcatagctt tgtcgtgtat tggcggacaa tccccgttca atattcaagt
    16381 agtggagata atcgttgatt tgctctttca taataatccc cctcatgcct ctctatcata
    16441 tcagataccg cttcattctg atagtctttt tccataatct gagcaaagaa aaagccgtct
    16501 agacactcag acggactggt ttctttttt
//
LOCUS       DAJSMK010000050        16522 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.052, whole genome shotgun sequence.
ACCESSION   DAJSMK010000050 DAJSMK010000000
VERSION     DAJSMK010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.052"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(58..255)
                     /locus_tag="ON488_001693"
     CDS             complement(58..255)
                     /locus_tag="ON488_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HCR3231889.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(649..2376)
                     /locus_tag="ON488_001694"
     CDS             complement(649..2376)
                     /locus_tag="ON488_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HCR3231890.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2369..3562)
                     /locus_tag="ON488_001695"
     CDS             complement(2369..3562)
                     /locus_tag="ON488_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HCR3231891.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3749..4393)
                     /locus_tag="ON488_001696"
     CDS             complement(3749..4393)
                     /locus_tag="ON488_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3231892.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4487..4621)
                     /locus_tag="ON488_001697"
     CDS             complement(4487..4621)
                     /locus_tag="ON488_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HCR3231893.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4623..6755)
                     /gene="feoB"
                     /locus_tag="ON488_001698"
     CDS             complement(4623..6755)
                     /gene="feoB"
                     /locus_tag="ON488_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HCR3231894.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6752..7225)
                     /locus_tag="ON488_001699"
     CDS             complement(6752..7225)
                     /locus_tag="ON488_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HCR3231895.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7626..7850
                     /gene="nrdH"
                     /locus_tag="ON488_001700"
     CDS             7626..7850
                     /gene="nrdH"
                     /locus_tag="ON488_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HCR3231896.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8009..10168
                     /gene="nrdE"
                     /locus_tag="ON488_001701"
     CDS             8009..10168
                     /gene="nrdE"
                     /locus_tag="ON488_001701"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HCR3231897.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10218..11183
                     /gene="nrdF"
                     /locus_tag="ON488_001702"
     CDS             10218..11183
                     /gene="nrdF"
                     /locus_tag="ON488_001702"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HCR3231898.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11272..12411)
                     /locus_tag="ON488_001703"
     CDS             complement(11272..12411)
                     /locus_tag="ON488_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR3231899.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12720..13433)
                     /locus_tag="ON488_001704"
     CDS             complement(12720..13433)
                     /locus_tag="ON488_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HCR3231900.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13687..14388)
                     /gene="nagB"
                     /locus_tag="ON488_001705"
     CDS             complement(13687..14388)
                     /gene="nagB"
                     /locus_tag="ON488_001705"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HCR3231901.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14622..16154
                     /locus_tag="ON488_001706"
     CDS             14622..16154
                     /locus_tag="ON488_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HCR3231902.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16345..>16522)
                     /locus_tag="ON488_001707"
     CDS             complement(16345..>16522)
                     /locus_tag="ON488_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3231903.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5124 a         3413 c         2864 g         5121 t
ORIGIN      
        1 cttatagata tatcattata taattcatga acaatttgct tagcattttt tttcatttta
       61 gcacttccct ggaattgctc cacctaaaaa accacctata gacattcctg caatacaagt
      121 agttgccttg gcccaatcga ccgtacattt atttttagtg caatacactc catttccata
      181 atattttcca ctatgagtgg tacccccata gataagttgt gtctctttaa tagacaaaat
      241 ttttaaatgt ttcataatct aatcacccct aaattaatgt ttttagacta ttattctaac
      301 attcattaaa tttcaaaaaa caattccttc ttgaaacgta gcaaaataat tcctgaataa
      361 gaatttaatc acttttaagt atataaacta tgtatattct ttaatatttt ttgagaatgc
      421 acttcgtaca taataaactt taatcacatt agtctttcat acctacgatc gatctctttg
      481 actcgcaccc ataaattcat aatagtttgt cggcgtcttt gaacgtttcg aagatgagct
      541 acgcattctc tttttttata gacaaaaaag atagagacga acatggagct tccaaatttg
      601 gatatttgat ccaattttgg aagctccatt tatttcgtgt ctgtcttttt attttttcca
      661 gctttcgact aattcttggt tctctttgat ccagtctttt gctgcttgct gtggatcttt
      721 tccattgttg atttccaaca taactttttc catatctttt tctgaccaat ggaaattgtc
      781 taatactttg taagcttctg gctggtcttc tttcaatcct tttcgaacca tcgtatggat
      841 ctgctcttcg cttcccattc cgttttcagg atcttctaag tatttcagat catatttggc
      901 aaacatccaa tgaggtgtcc atcctgtaac tacaattggt tcgtgttttt tgatcgcttg
      961 acctagtgca acggtcattg ctcctgaaga agatgtctct actttccagt ctttcaagtt
     1021 gtcatatttt tggatcgtgt tttcagcagc cgtaactaca ccagctcctg gctcgattcc
     1081 tatgattttc ttacctgcct gatcggttaa ctcatcgatc gaatttacat ccatgtaggc
     1141 tggcactgct aaaccaactt ttgctcctgt caaattggca cctaggtctt cgacttgatc
     1201 tttatattgt gcatattgtg aaccatgagt tttaggtagc caagctgaaa ccatggcatc
     1261 tgactcgcca tttgaaacag atttccacat gattgaatta tctaatggcg tcatcgttac
     1321 atcatagccc atttgtttca atacttcacc gactacattt gttgaagcaa cttctgtatc
     1381 ccattcaaca taagataagt tgatacgttt tgtttctttg gcagatgaaa aactccctat
     1441 accaatcgca cctaagatca ctactactac agcaccaatg atcagtcctt gacgtttttt
     1501 acttttctgt gttgttgctc ctgcagcttt tttattgttt ggctggttca aatgctgtgt
     1561 aaaacggtca atgatgattg ctaagataac taatgcaacc ccgttgacaa atccattccc
     1621 gacttgtgct ctttgcaatg ctgataatac gccgcgtcct aagccgggtg caccgatcat
     1681 agaggcaata acgaccattg aaagtgacag cattgttgtt tgattgatcc ctgccatgat
     1741 cgtactttta gctaaaggca attctagttt gaatagtttt tgacgacttg tgctcccgaa
     1801 tgaatcagaa gcttctacta attctttagg aacttgtcga atccctaaat tcgtaaaacg
     1861 aacggttggt ggcagagcaa agatgactga ggcaaatacc cctggaacca tcccgatacc
     1921 gaaaaatgca actgctggaa tcaaataaac gaatcctggc attgtctgca taaagtcaag
     1981 gatcggtttg ataatacttt gggctttact gctttttgcc atcaagatcc ctaatggtac
     2041 cccaatgatg atcgagatca cactagataa aagaacaagt gtgacagtat tcatcaaatc
     2101 attccataga ccttggttat aaataaacca tagaccgatt aatgtgaaca acgtaagtcc
     2161 tggacgtttc ttagaaataa agaaagctgc taccgtcaat aacaagataa acaaaggagc
     2221 tggaatcact aacagtaaat ttgtaatccc cgacatcact gcctgtccaa tcgtttgtaa
     2281 aaatgaaaat aggccagaaa aagttgtcgt aaaccattct gtgatatttt ctacccagtt
     2341 tgccactggt aattgatagt tcaatagatt attcatgttc actcacctcg cttgtttctg
     2401 ctaatgcttc aatcacacta cctcggatga cgacaccttt taattttcca tcctctacaa
     2461 ctgcaagtgg agtcggtgag tcataaataa tattgaaaat atcacttacc accatgtctt
     2521 tcccaatcac cgtcacattt tcatctagga agtcgatcaa tggacgtttt tgcttcctag
     2581 cttctaacgc ttgatctgca gtgatgatcc ctttcaggtg tctctttctg tcaacagcca
     2641 tcagcatgct gacttcttca ttacgcatcc ttgtcaatgc aacgtttggt ccatcagatt
     2701 cgatattcgt cgtcaatgca ggtaccatga tgttttgagc cgtaagcact ttggaacgat
     2761 cgacttcttc cacaaattca cgtacataat catttgctgg attggtcaat atttcttcac
     2821 ctgttccgat ctgcatgatt tcgccgtctt tcatcaaggc gattctgtcc ccaatccgta
     2881 aagcttcatt caaatcatgg gtaatgaaaa taatcgtttt ttgaacattg gcttgcaggt
     2941 ccagtaattc gtcttgcatt tctcgccgga tcagcggatc aagagccgag aacgcttcgt
     3001 ccatcagcaa gatctcagga tcatttgcta aagctctggc taggccaacc cgttgttgca
     3061 tcccaccaga taactgacta ggatattggt ctttaaatga aagcaaacta gaattttcta
     3121 atgctttttc tgctttttct tgtcgttctt ctttaggtac accacggact tctaacccgt
     3181 attctgtatt ttccaagatc gttcgatgtg gaaacagacc gaagttttgg aaaaccatat
     3241 tgattttatg acgacggact tctcgcaatt cttctttgct taacttcgat acatcttctc
     3301 catcaatata gatactgccc gaagttggct caatcagacg attcaataga cggatcaatg
     3361 tggatttccc actcccggaa agccccatga tcacgaagat ttctccttct tttacgtcaa
     3421 aattcacgtc atacacacca accgttgcac cggttttctt taaaatctcc gttttcggct
     3481 ggtgatcatt catcatatct aaagcggctt gtgtcttttt accaaatatc tttgttaaat
     3541 gttttacttc tacttttacc aaacaaattc tcctttttta tgtaaattca tttttctttc
     3601 tgaaaaaagt gaccacacta tgttaacatc atgtagtcac tttgtcaaaa atgaaagaaa
     3661 tttgcttgtc caaactgaaa aaaacttggc taaatctttg taaataaaag gtttagccaa
     3721 gttaatattt ttttaatatt tcacacaatc attctgcaag ctgatgctcc gggtaaaaaa
     3781 agtttgtcat acgctgtagt gtatattcat ttccaataaa atgaacgatg tcccctgccg
     3841 taaatttagc ataggggcca ggtgaaacaa gcagttcttc attatgagaa attgcgataa
     3901 ctgtggcgcc agtcgcctgc cagatattca actcgctaat tgaacggtcc agatgcattg
     3961 ctttttctga taaagataat tcaaacggaa gtaaaggatt catcttatgt attcgcttcg
     4021 tttgattgac cagctgatcc aataattgag aaaaatgatt cagctcatct tgttgcttct
     4081 ccacacttgc catgatttct gcttttgtat cttggatgga ttgtacatct tgatattgca
     4141 ataggaaatc ttttgctttt tccttcgaag caacaaatgc cccacttcca tgccgtactt
     4201 ccatgattcc aagatctacc agcacattga tagccttgcg ggtagtctca ggagaagcat
     4261 tgtacgtact ggcaagtgtt gagcgggcat ggatcttctc acccacttta tatcggtttt
     4321 caacgatacg ttcggctaaa tcaacagcaa tctgctggta gcgcgggcgg acgatttttt
     4381 tctttccaga cattttcttt cctctttctt tttttacttt ccctcatctt actatgctct
     4441 agcaaaataa gcaaaaaagg ggagaatagc ctcttgcaac gactgatcat cgcttgatct
     4501 gttccttttt tactgggcaa gctgtttgac agtcatcaca attcttaccg gattttaaac
     4561 gagtatagac aattgcgcct gcacttccaa agattaacac acttaataag aatgtcgcca
     4621 tcctattcct ctccttctaa tgacaatata gtataaaact ggttcttgga ttttggctga
     4681 cggaacaaaa cataaacgag tcctatcatc agtaaaatag caagatacgt ccctaacgct
     4741 acctgtccac cctccaataa gtgtcccaac tgataaatca caaaactaac taaataagct
     4801 aaaccgcatt gatagcctat ggcgatccaa gtccatttct tggcattcat ttcccgatgg
     4861 atagccccaa ttgccgcaaa acaaggcgca caaagtaaat tgaaggctaa caatgaataa
     4921 gctgctgcgg gagtatatgt gtgttgtagc acttgccaga tttctctgcc attttcggat
     4981 acttccgcat gaccaaacaa aataccaaat gtgccaataa tattttcttt agcgaccaat
     5041 cctgtaatcg ctgcgactgt tccttgccag tttccccaac caagcggctg aaaaacaact
     5101 gccaggattc gcccgaaaaa ggctaagata ctttggtctt cagaaacagg ttgagcataa
     5161 aaattataag aagagctgaa ccagatcacg atactagaaa caaagataat cgttcctgct
     5221 tttttaacaa aagacttgct gcggtcatag gtttgtctta ggaccgctga ccattgagga
     5281 aaatgatatg cgggcaattc catgataaaa ggagctgtat ctccagcaaa caaacgtgtt
     5341 tttttcaagc tgattccaga gaaaataatt gcagtcatac caagaaaata ggcagaagga
     5401 gctacccaag attgatgagg aaaaaaggcc cctgctacta aggcaataat cggcaacttt
     5461 gcagaacaag gcatgaaggt tgtgaccatg atcgtcaaac gacgatcttg ctcgttttca
     5521 atcgtgcgac tggccatgac gcctggcact ccacatcctg tagcaatcag cataggaatg
     5581 aaggattttc ctgaaagacc gaatttcctg aaaagtcgat ccatgacaaa agcgatcctc
     5641 gccatatatc cgcagtcttc cagaaagctc aagcataaaa acaatataat caattgcggt
     5701 agaaatccta acactgctcc cacgcctgcg atgatgccgt tcaagatcag ctcctgcatc
     5761 catcccgcta cttgccattc agctaacaat ctgccaacat gttctggtaa ccatgtacca
     5821 aacaatgtgt cattgatcca atctgtcccc attgttccta ctgtttgaat agccagataa
     5881 tagatcagcc acatcacaaa tgcgaagatc ggcaaggcta accaacgatt cgttgcaatc
     5941 tgatcgattt tgtcactcat cgataattgg aaagaatcat ttgacacaac acagagtgta
     6001 catagttggg taataaattc ataacgttca ttgaccagaa tcgtctcact atcgtcgtcc
     6061 aatagtttct ctgttaactg gatcagttgc tcgatctctt tttgctgaga aactgctatc
     6121 tcgtaatcct ctcttacctt ctgatctcgt tcaaaatatt tcattgcata ccagcgtttc
     6181 ttgccgcttt gttctcctag tacatcttca atttcatgta aagctgcttc taaacgtgga
     6241 tcatatgtac agggaacagg aatagaaggc cgcttttttg cagactcctg aatcttttcg
     6301 attagttttt cgattccttg ctttttcaat acgctgattg gtaaaactgg tacaccaaga
     6361 ccataggaaa gcttttctag attgattttt tttccttctt ttttgatgac atccatcata
     6421 ttcagaccaa tgatcatagg aatgtctaaa tccaataact gcgtagttaa ataaagattt
     6481 cgttctaaat tggtagcatc aataatgttg atgatcagtt caggctgttc ctgaaccaaa
     6541 taatctcttg caatcacttc ttctggtgta taaggagaca aagaatagat gccgggtagg
     6601 tcctgaatat gaatgttcgg attttttttc aacgatcctt cttttttttc tactgttacg
     6661 cccggccaat tccctacata ttgattcgaa ccagtcaaga gattgaacaa gctagttttc
     6721 ccgctgtttg gatttccgac taacgcgata ttcattcttt ttcctccctt tgtatcaaga
     6781 ttagttcggc ctctgacttt cgtaacgtca gttcataccc tcgcactgtc agttcgattg
     6841 gatctcccag aggggctagt tttcggataa ctatttttac atttcgcgtc aatcccatat
     6901 ccattaaccg tcgcttcact gcgccttgtc cgtggattgc tacgacgatc ccagtctctc
     6961 ctgcttttaa ttgatcaaga gaagtccagc tttcagagga agcagtcttt ttattgacaa
     7021 agatttgacc tagtatttcc cgacttactg ccactcgatg actttttacc agtaaaatgg
     7081 cattgttgcc tgataaattg acgacgacga ttttacttcc ggcaacgatc ccgatatttt
     7141 gcaaatggcg ttttgttttt tcttctgttt cgattcgttc gacttgataa acgaaattct
     7201 gctttgcctg cgctaaggtc tgcatattga ttcctctctt gtgaaataaa tcatgtatta
     7261 aaatcattca ttatatgttc taattttctt acgtgttacg caaataaatg agaatcattc
     7321 tcacatagaa tactctcggt aattgagaat gtcaattata cttgtgatat tatgagcgaa
     7381 tctttagtat tgatagataa aaatgagaaa aaaatatttc ttcatagttt tccacaattt
     7441 tttctctatt aaatttgcta ttttcccaca cgatacttgt tttcagctct tttttcaaaa
     7501 acacaaaact tagtattcca cagtttccac aacacaatat gtagtgtttg ttgtttgact
     7561 tttttactaa gagttttata ctatctatta tagataataa gaatgtgtta gaggaggcac
     7621 tcaccatgaa cgtaaaaatc ttttctaaaa ataattgtat gcaatgtaag atggtcaaac
     7681 ggtttttaac agaaaatcaa attgcttttg aagaagtcaa tatcgatgaa cagcctgaag
     7741 cagtagactg gttgaaagca caaggattcc aaagtgttcc tgtcattact tctgatgcag
     7801 aaacagttat cggattccgt cctgatcagt tgcgtaaact tgccagctaa catgactaaa
     7861 agaatcaaaa cgtgatacat ggatttgaag ggcttgagac agcaccagtt tttgtcgcaa
     7921 acttccaaat ccttttttaa agcttaaaaa caatgcaatg atttgcaatc aagcatcatc
     7981 aaatacgaaa tgaaggttgg gcgtacgtat gagtcttaaa aatttacaag atgtcagtta
     8041 tttcaagctg aataatgaaa tcaatcggcc agtcaatggt caaatccctt tgaataagga
     8101 taaagaagct ttagttgcct tttttgagga aaatgtcaaa ccaaatacga tgacttttcc
     8161 atctattatg gaaaaaatca attacttgat cgatcaagaa tatatagaag cagaattcat
     8221 tcaattgtat tcaccatcat ttattgaaaa gctatatcaa tttttggacg agcaacattt
     8281 ttctttcaaa tcttttatgg ctgcttacaa attttattct caatatgcgt tgaaaaccaa
     8341 cgacggttcc gcttatctgg aaacttatga agatcgagta gccttcaatg cgctttactt
     8401 tgcgaacggg gatgaagaat tagcacttgc tcttgcagac gaaatgatcc atcaacgata
     8461 tcagccagct acaccttctt tcttgaatgc tggacgtaaa cgtcggggcg aattggtgtc
     8521 ttgtttcttg actcaagtca ctgacgatat gaactctatc gggcgctcaa tcaactctgc
     8581 tttgcaattg tcccgtattg gtggcggcgt agggattact ttatcaaatc ttcgtgaagc
     8641 cggcgctcct atcaaaggat atgagggtgc tgcaagtggt gtcgttccag tcatgaaatt
     8701 attcgaagat agtttcagct attctaatca attaggtcag cgtcaaggag ctggcgtggt
     8761 ttatttgaac gttttccatc cagacattat tgctttcctt tcagcaaaaa aagaaaatgc
     8821 agatgaaaag attcgcgtaa aaactctttc tcttggcgtg atcgtacctg ataaatttta
     8881 tgaattgaca cgtaaaaacg aagatatgta tttatttagt ccatatagtg tcgaaaaaga
     8941 atatggtgtc ccattctctt atgtaaatat tacagctgag tatgatcatc tagttgcaaa
     9001 tccaaacatt cgcaaacaaa aaatcaaagc gcgtgatctt gaaaatgaaa tctcaaaatt
     9061 acaacaagaa tctggctatc cttacgtaat caatattgat acagcgaacc gcgagaatcc
     9121 aatcgatggc aagatcatca tgagtaattt atgttcagag attttacaag ttcaaacgcc
     9181 ttctgtgatt aacggcaaac aggaatatga agtattagga acagatatct catgtaactt
     9241 aggctcgaca aatatcgtga atttgatgca aagccctaac tttggtcaat ctgtgcgtac
     9301 gatgactcgt gcattgacat ttattacaga tgcatctgat atcgatgtcg taccaccgat
     9361 ccaaaacgga aataagctga atcatacgat tggattaggt gccatgggct tacacactta
     9421 tcttgcaaaa gaacaaatgg aatatggctc agaggattca ttagacttta caaatattta
     9481 cttcatgctg ttgaattatt ggacacttgt tgaaagcaac aatatcgctc gtgaaagaaa
     9541 acaagttttc cataattttg aaaaatcagc ttatgctgac ggcacttatt tcgaaaaata
     9601 cgtaactgga gaattccagc caaaatcaga aaaagtcaaa gcattgtttg aaggcatttt
     9661 tatcccaact gctgaagatt ggaatgcttt gaaacaagca gtaatgaaag atggactgta
     9721 tcatcaaaat cgcttggcag tagcaccaaa tggctcaatt tcatatatca acgatacgag
     9781 tgcaagtatt catcctatca ctcgcatgat cgaagaacgc caagagaaga aaatcggtaa
     9841 aatttattac ccagcgcctt atctatccaa tgagacgatt ccgtattaca cttctgctta
     9901 tgatatggac atgcgtaaag taatcgatgt ttatgcaacg gcacaacaac acgtcgatca
     9961 aggcatgagt ttgactttat tcatgcgttc tgaaatccca gaaggcattt atgaatggaa
    10021 gacaacaacg aagcaaacga cacgtgattt gaatatttta agacattacg ctttccacaa
    10081 aggaatcaaa tccatttatt acgtacgtac ctttactgat gatgcagaag aaatcggaag
    10141 caatcaatgt gaaagctgcg tgatctaata tcatagatag attcgcttat tcatatttta
    10201 attaaaggag cattctcatg tcagaaacat attatgaagc aataaactgg aatgaaattg
    10261 aagatatcat tgataaatcc acttgggaga agctgacaga gcaattttgg ctagatacac
    10321 gtatcccact ttcaaatgac ctagatgatt ggcgtacatt gtctcaattg gaaaaagata
    10381 cagtaggaca tgtatttggc ggtttgacac tgctagatac tgtccaatct gaaagtggca
    10441 tggatcagtt gcgtaaagat gtccgcactc cccatgaaga agccgttttg aacaatattc
    10501 aattcatgga atccgttcat gccaaaagtt attcttctat ttttagtaca ctgaatacga
    10561 aaaaagaaat cgaagaaatt tttgactgga caaatacgaa tccttatctg caaaaaaaag
    10621 ctgagcgtat caatgaaatc tacaaacacg gtacaccgct agaaaagaaa attgccagcg
    10681 tctttttaga aacattcttg ttctattcag gtttttatac tcctctttat tatttaggaa
    10741 acaacaaatt ggctaacgta gcagagatca tcaaactaat catccgagat gaatctgtac
    10801 atggaaccta catcggttac aaattccaat taggattcaa cgagttacct gaagcagaac
    10861 aagaaacgtt aaaagactgg atgtacaatc ttctttatga gctttacgaa aacgaagaac
    10921 gttatacaga agaattatac gatccaatcg gctggacaga agaagtcaag acattcctac
    10981 gctataatgc caacaaagca ttgatgaacc tagggatgga tccactcttt ccagatactg
    11041 ccaatgatgt caacccaatc gtaatgaacg ggatttcaac aggcacaagc aaccatgact
    11101 tcttctcaca agtcggaaac ggctatttgt taggtcatgt agaagcgatg aaagacgacg
    11161 attatttgat tggattggaa taaggattta ttttaattca aaaatttttc gaaaaataaa
    11221 aagagtttag cgtacagata ttttaaatgt acactgaact cttttttatg cttattcact
    11281 tgtttcttcc agcacttttg gactgtctaa cttttccgaa acatgttcca ttcttctcaa
    11341 taaatagatt ttccggatat ttaatattat cgtcttaatc actgcataga caggtatgca
    11401 aatcagcatg cctaatattc ctgcgacact tcctgctcca atcaatacca agatgatcgt
    11461 caaaggatgg atattcattg atttcccaaa taacaacggc ttgatcaaat ttccatctaa
    11521 ttgttggatc actaaaatcg acaacgccat atacaaagct tgaaatggag agataaacaa
    11581 accgacaatg attgctggta ccgctccaat aaaagggccg acatacggga taatattcgt
    11641 gattccgcaa atgaccgcaa gcaacaagct ataaggctga tcgaatattc tcattgccaa
    11701 aaagctcatt acaccaataa tcaaagcatc taagatcgta ctgctgatat aggcagataa
    11761 tgtttcgttt aattctttta ccgtttggcg taactcttta cgaatcgctt tcggaaagaa
    11821 gtgagacaac gcatcaataa atttgtgccc atccttgaac ataaatagca aaataaatgg
    11881 aacggtaaat aacaaaataa aaaattgcat cataaatgaa atgatttttg agacacttgc
    11941 agataaactg actaatatga tattgaacaa attactaaga gataaatttg ctgatgctaa
    12001 ttgttcttcc aaattgaaat ttttaaactc ttcccgctgc gccaattcat ttaaccattt
    12061 gcttgtttca tctgcataca ttggcaagct ctgggtcaat tgaattgtct gttccattaa
    12121 ctgaggcact acattcatga cagttaaaac aactaaaatg attacgacca aaaacgtcaa
    12181 taaaaaaccg aacactctcg ggatccgatg cttttcgaga aaaacaacga ttggatcgaa
    12241 catataatag ataaaaccag caacaagcaa tggtaaaaaa attgccgaaa gcattttcaa
    12301 tattggacta aaaatattcg gcatttgtaa aataaagtac acgccgatga tcgtgagtac
    12361 tagctccact gtccagaaaa ataattttga ttgtttaaaa cgtgattgca tacatctcct
    12421 ccaaggtcct ttgatacttc tattctatca tttaacaaag agttacgcgc tgagattttc
    12481 atttgcttaa aaaaaacaaa aaaaataaac atattttaat gagtagacga gtacttaaac
    12541 aaaaacacgg tttggagtag tgacaaaaat tatactgcag tccctttttc caaataaacg
    12601 gtgttcaaaa gcttgcatct tcgtaataag cccagccaaa cgaaaaatat aaggaactat
    12661 ttttatttgg ctgggcttat tacttgatgt aggacatcta ttttacaacc tcagatcatt
    12721 tattgcgcaa tactgactaa atgcaacttt gtgatatttt tgtgtacgga caactcctcg
    12781 atcacatcgg cataagtgag cccttttgga agatcaatcg tatagatatt tttgtacact
    12841 cggtagtcat caacgaattt tacgtcaaaa ttcacatctt cgattacgat atttttctct
    12901 tcaaaataat cggtaagaaa atctttggtt tcttttctat ggataaattg gatttctaac
    12961 tttttagtcg taggtacatg gatcacgcgt ttcactactg tgagtgcaat agcaatcccg
    13021 ataaaactga tgatcgcaat ggaatagtaa cccatgccga tggcgatccc taatccagca
    13081 attgcccata aagaagcggc agtcgtaagt cccgtcaccg attgtttcgt gacgatgatc
    13141 gttcccgcgc ctaagaaacc gacaccactc accacttgag caatcagcct tgcttcatct
    13201 gaacgaatcg ttccagcaag ctgtggatac tctaaagcat ctcttaatgc accactagcg
    13261 atctcaactt ggatcaatgc aatgatacat gctcccatac aaactaaaat atgcgtacgc
    13321 atacctgctg gacgattttt atattgtcgt tcaaaaccga ttgctccgcc aaatagcata
    13381 gcgatcccta aacgtaaaat aatctctgga attgtcaata ccatatcatt catctaaaca
    13441 ccctccagtc caatatatca tgtctgaaag gagcagacaa aaaaagtgca atttttacct
    13501 cttacgaaaa aaggactgtg acaaaatttt tgtcatagtc ctttttatga ataaacggtg
    13561 ttcaatcagc tgaccctcgg tattactcaa caaacggcaa aatatgggga gctatttttc
    13621 ctttgtcttc tctaatactc aggtcaaaac gctgatttca caacctcttt agcctactat
    13681 tgaaaattac aacttacttg ctgcttcttc atcgatgatc acaacaacat tgtcgtgatt
    13741 ttgcaataca cttgctggca aatgattcgt tacaggtcct tcaatcatcc ctttgattgc
    13801 atcagctttg ctttcgccaa atgccatcaa gacgatttct ttacttttca taattgaacc
    13861 gattcccatt gaaacagctt ttgttggtac atcttctgct ttatcgaaga atcgtttgtt
    13921 tgcattgatt gttgattctg ttaagtcaac tactgaagtc gttccgtcaa atgaagcacc
    13981 aggttcattg aaaccgatat gtccattttg cccgattcct aagatttgga tatcgattgg
    14041 atgtgcatcg atgatttgat catacttttt gcatgctgct tccagatctt ctgcttttcc
    14101 atctggtaca aacgtttctt tgaatggttt tttatcaaat aattggacat ccatgaaatg
    14161 acggtagctt tgttcatctg aaccgcctag tccaacgtac tcatctaagt ttacagaagt
    14221 catttcactg aaatccaaat cgcttgaagt catttcttta tataaagtaa ctggtgtgct
    14281 tcctgttgcc aatcctaata cttttgcacc tttgttcata ccttctttga tgatttcaaa
    14341 tgcttttttt ccgccttctt cagcgttttt tacacgaatg atttccatag tgattgctcc
    14401 tttatatttt ggtatagccc aattatagca ttcttttttt ctttttacaa taattagtat
    14461 agaccaaatt gcattttttt cattttcttg acaataaata ggaatccgtg ttaggtttca
    14521 taagatggtt caatcaaaca atccatgttg catgaaaacc aagcaagtga ttcactgtgg
    14581 acgctttatg tctgcagttt ttttatgaaa aaggagttat tatgagtata ctgacattaa
    14641 acaacattac ccagcaattt ggcgacaaaa tcctctatga aggtgtcgat ctgcaattaa
    14701 atgctggcga acatcttggg ctgattggac aaaacggagc cggtaaaagt acattgatta
    14761 aaatcatcac tggtgagatc ttaccagatg acggacagat ccattggcaa aaaaatattc
    14821 acaaaggtta cctcgatcaa tatgtggaag tcgatgaaac attaacaatc gaagaatttc
    14881 taaaaactgc gtacgcaaaa gaatacgaaa aggaagaaaa aattgctttt ctttaccaaa
    14941 catatagcga gaccttcgat gattccttgc tggaaaaagc tgggaaactc caaacggaat
    15001 tagaccaagg agtgttttat caaatcgaca ccttagttgc tgagatgagc agcgggttgg
    15061 ggatcgatgt cttaggttta gattcactgt tgaaaaatct aagtggtgga caacgttcaa
    15121 aggtgatttt agcaaaacta cttttagaaa acccagatgt tctgatctta gatgaaccaa
    15181 ccaatcactt agatgatcag catatccaat ggctgacgca gtttcttcag gattttgacg
    15241 gtgcgtatat cgtgatttcc catgaccaag aatttcttga tcagatcacc acccatatcg
    15301 cagacatcga gtttggaaag attactaagt atactggcca tctaaaacaa gcattgaaac
    15361 aaaaggaaca aaatcgcgaa agctatttgc gccaatatca tgctcaacaa aaacaaatcg
    15421 aaaagaccga agcttatatt cgaaaataca aagccggttc ccgatcaacg atggcaaaaa
    15481 gccgacaaaa acaattagat aaaatcgaac ggctgacgcc tccagcttca gcaagtaaag
    15541 ctgtctttga ttttccattc tcgcctattg tcacgacatt agcagtggaa acaactgatt
    15601 tagtcatcgg atatgatcga ccgctacttg cacccatcaa tttgaccatc cgctttggtg
    15661 aaaatattgc cattcgaggc ttcaacggga ttggaaaatc tactttatta aaaacactga
    15721 tcggtgagat tgaaaaaata agtggcgatt tccacttccc agataacaca aaaatcaatt
    15781 acttttcaca agatctgtac tgggaaaatc cattagaaac accactacaa tatttaagca
    15841 gtcaatttcc aaaagcgact atcaaagaat tacgtcgcca actagctaaa gcagggttag
    15901 ttaatcaatt agcaagtgaa cctctcacta cattaagtgg tggggaacaa actaaggtga
    15961 aacttgcaca gttgacaatg aaccaaggta atttactgat tctcgatgaa ccgacgaacc
    16021 atatcgatca agaaacgaaa gaaagcttac aagacgggat acagaaattt ccaggaacag
    16081 taatcatcgt ctctcatgaa caagaatttt atcaagatct tgtgcaacga gtcattgaga
    16141 ttgaaccaaa ataaacgttt gattgaatag ttgaaaaaaa ggagctgtga caaaagtttt
    16201 gtcacaactc cttcttctga ataaatggtg gccaattagc tgaccttcgg tattagctca
    16261 aaaaacggca aaatatgagg agctattttt atttggctat tcttattact tgatgcagaa
    16321 cagcttttca caacctcttt tcgtctattt tttattttcg agatttctct ttcctttaaa
    16381 aacaactgtt tgaaagaaga acgcacatcc ttgaaaaaca agcccgctaa ccgttacacc
    16441 taaccagcca tactgctgcc acattgtcgt ccctagcaat gaaccagccg cacctccaat
    16501 aaagtacata aacataaata ca
//
LOCUS       DAJSMK010000051        16035 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.053, whole genome shotgun sequence.
ACCESSION   DAJSMK010000051 DAJSMK010000000
VERSION     DAJSMK010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.053"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            226..894
                     /locus_tag="ON488_001708"
     CDS             226..894
                     /locus_tag="ON488_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HCR3231904.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(1094..1480)
                     /locus_tag="ON488_001709"
     CDS             complement(1094..1480)
                     /locus_tag="ON488_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231905.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(1452..2834)
                     /locus_tag="ON488_001710"
     CDS             complement(1452..2834)
                     /locus_tag="ON488_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCR3231906.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            complement(2990..4177)
                     /locus_tag="ON488_001711"
     CDS             complement(2990..4177)
                     /locus_tag="ON488_001711"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HCR3231907.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            complement(4184..5215)
                     /locus_tag="ON488_001712"
     CDS             complement(4184..5215)
                     /locus_tag="ON488_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HCR3231908.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            complement(5231..6685)
                     /locus_tag="ON488_001713"
     CDS             complement(5231..6685)
                     /locus_tag="ON488_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3231909.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            6860..7765
                     /locus_tag="ON488_001714"
     CDS             6860..7765
                     /locus_tag="ON488_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR3231910.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            7856..8533
                     /locus_tag="ON488_001715"
     CDS             7856..8533
                     /locus_tag="ON488_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCR3231911.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            8530..8700
                     /locus_tag="ON488_001716"
     CDS             8530..8700
                     /locus_tag="ON488_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231912.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            8814..9710
                     /locus_tag="ON488_001717"
     CDS             8814..9710
                     /locus_tag="ON488_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCR3231913.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(9765..11135)
                     /locus_tag="ON488_001718"
     CDS             complement(9765..11135)
                     /locus_tag="ON488_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3231914.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            11373..12120
                     /locus_tag="ON488_001719"
                     /pseudo
     CDS             11373..12120
                     /locus_tag="ON488_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
     gene            12117..12956
                     /locus_tag="ON488_001720"
     CDS             12117..12956
                     /locus_tag="ON488_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HCR3231915.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            12957..13907
                     /locus_tag="ON488_001721"
     CDS             12957..13907
                     /locus_tag="ON488_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HCR3231916.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            14048..14800
                     /locus_tag="ON488_001722"
     CDS             14048..14800
                     /locus_tag="ON488_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231917.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            14819..15970
                     /gene="queG"
                     /locus_tag="ON488_001723"
     CDS             14819..15970
                     /gene="queG"
                     /locus_tag="ON488_001723"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HCR3231918.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
BASE COUNT         5200 a         3004 c         3229 g         4602 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacggt tgtgtaaaaa tatcatttta gagcataaaa
       61 aaaaggagtg gatttctcca ctccaaaaaa gtctaacttt tgggggtcac tacagtgtca
      121 cagtcctttt tttagtaaaa ggatacattt cttccttgta tattccatgc gtgttcgtga
      181 gaaagcatat ataatttaat taacagatag ttagggggag aaaaaatgat tttttcaatt
      241 acaatgaaac tggtgttcgg gttgatcggt ttattattag tggtacgttt gcttgggaag
      301 aaatccatgt cagaaatcac accgtttgat ttagtctata cgcttgtttt aggtgggatc
      361 ttagaagaat caacctatga tgacaatgtc catgtagggc atgtcctatt tgccattgcg
      421 ctttgggcag taatgattta tggtatcgaa cgtatcgtcc aaaaaaatga aaaggtcaat
      481 cgttgggtca aaggcgagcc atctgttcta atcaaagacg gcgtcatcaa catgacagag
      541 ttgacaaata accatatcga gatggagcag ttgcgagcaa tcttaagaca gcaagaatgc
      601 ttttttcttg aaaatgccaa acatgttatc ctagagaatg ccggtcaaat gagtgtattg
      661 aaaaaatcag atgaagacaa agctttatcg atcctgcttg tagatgaagg gcaaattcag
      721 cataaagtgc ttcagtccaa tcaattgact gaagcatggc ttatggagaa cttgaagaaa
      781 gaaggctatg cagatgtaaa acagctgatt tatgttgaat ggtcagaaga aaaagggctc
      841 tacatactaa ataaagaaga cgtcatgcat gaatcttacc gaatagatgg atagatagac
      901 agaggttgtg aaatcagcgc cttggcttgt tactcaaaac taagcgactt tttcacaacc
      961 tctgatatct aatatacgtt gttccagaag ttgcttcttc gaaaaataag ccaaaattcc
     1021 acaaaaattt aagaagcaat tttcgaaaaa tcctttctta ttttttgaag ttgatcactt
     1081 ctgtcacaac ctctcatgtc acaaaccatt tttttgtttc ctttaactca atataccgta
     1141 cgtcttccca caatatcggc tgatggtcaa tcataaagta atcttcatag gcttcaccaa
     1201 tgaagtgccc ttcgacctca tccaagagtc ttccaaattc atcttttaaa ttgagctgaa
     1261 tgattactgc tttacgagat aaaaaggctt ctgtcagtat actatcgatt tcttgcaatg
     1321 tcatttgttg tttaggaaga ggctgtttgc gtgcttcttc ttcatttttt ttgataccgt
     1381 tgactagttc ttccatcgca aaagcagtcc cccattttaa tccaaatggc cgatctcgat
     1441 actcgttata gtcaatgaat ttttttgctg tccgtctcat cttttccacc ttctaatcca
     1501 ctcataccac ctgcatgccc gccaacgaga gaactacgtg cgatggcgcg tcctccttgc
     1561 aagagactat gcgcatggat gattgattga aagccgtatt tttttctaat cgtatcgaca
     1621 acaaaatcaa ctttcgcttc atttatctgc ttttcaggat cttcaaaaag gttaagctgt
     1681 aaacctgtcg cgtatacgag gtcggaacag ttcacgccta cacgccgaat atcctggtag
     1741 tggtaatgct ggtggaaaat ggtcaataaa gcatctgcta gatctctgct agcatttgtc
     1801 gcttcgattt tcatttgctg gtgaaacccg gtcttgccat ttggatcaag atagcctaaa
     1861 gagtatccta cccataagct gactacttgt gtttttgctg cagatcgtct caagcgagtg
     1921 ccgacttggt cggccatttc tttgataacg atctcgattt cttctcgtct tgtataatct
     1981 ctatctagga tttgactatt tccgatactt tttgattttg gtgtatattc ttgtcccaaa
     2041 aaacttcgat cgatgcccca agcatgggca taaagctgag taccgatgac ccctagcttg
     2101 cttttcaagt gataataatc cgcgtgagct aaatcataaa cagaatgtat acccatttgt
     2161 ttcagacgtt ttgctgttcg tttgccgatt ccccaaaagt cagtgatatc tgagattttc
     2221 cataactttt ctggtacatc ttcataacgc cattcagcaa acatttgctt tccgtctttt
     2281 gagccattgt ctaaggctag tttagcaagt agcgggttat cgccaattcc tatagtcgtg
     2341 tagattccgg tctgctcaaa cacatcttta tggatcagtt tagccatgtc gtacgcattt
     2401 gttttaccaa agagtgccat gctatttgtt acatcaagga agctttcatc gacggaatag
     2461 acatgatggt tcgcttcgtc tgcatatttt ttatagatag aattgatttc tctgttcttt
     2521 tccatataat aggccatcct tggggcaaca atatataaat cacttggata ggggaaggga
     2581 agatctctgg cacggctgat attggtgatg ccgtaagctt tttttgctgc aggactggaa
     2641 gccaagatta atccgctacc ccgtgtttct gtcgaatcgg acggatagga catgactact
     2701 aatttagttg taaggggatc aagatccttt tcaacgcact ctacggaggc gtaaaaagat
     2761 ttgcagtcaa tacataaaat atctcttgaa ggttcttttt cataaacaaa taccggattt
     2821 tgattcgccc acataacaat cacctcttca acacaattag aacacacgtt ctctttccgt
     2881 gtcaataaaa aacagcaatt ttcaaatacg agcaaaaggc tcacatttgg aaattgctga
     2941 gaggttattt ttatctattt gtttttagct gagatcgttg atttttttat caaacatgaa
     3001 cagcttctgg atcgatcttt gttgtcccat ttccaatgtg tgcaacataa aattccggag
     3061 catagccgac aactttcatg tattcatcat agacattgtt tttgaaggca ggtatatttt
     3121 cttctttgac aagagcaatc gcacagccac caaatccagc tcctgtcatt cgtgcaccta
     3181 agacaccttc ttgtttttga gcagcatcta ctagtgtatc taattcgatc ccagttactt
     3241 cataatcata gcgaagagag tggtgagaat catttaacag ttgaccaaat gcttctaagt
     3301 tcccagcttc taattcagct tttgccttca aagtccgctg attttcagaa acggcatggc
     3361 gagctctgcg tatcaatgta tcatcgccga tttggtcaat agttgattca aattcttctt
     3421 catctaagtc tcctaaagaa gagataggca aagttttttg caaacgtgcc aaggcttctt
     3481 cgcattcgct acggcgttca ttgtattttg aatctgccaa ttcccgccgc ttattcgtat
     3541 tcatgatgac gattgcataa ccatctagtt tcactggaac catttcgtat ttcagcgtat
     3601 ttgtatctaa taagattgca tgatctagct caccgaagcc gatggcaaac tgatccatga
     3661 tacctgaatt gacaccgatg aattcatttt ctactttttt acctgtttgg actagttcca
     3721 agcgatctgt ttttaaatca aacagatctt ctaatacaac acctactaat aattctaatg
     3781 aagcgctact ggaaagtcct gcaccattag ggattgttcc ttccactaat aactcaaacc
     3841 catgatcgat tgagtgtcca gcttctttta atttaaggac cattcctttt acgtaatttg
     3901 cccagtttgc ttttttatca tattctagct catctaaagt aaaactaatg acaccgatat
     3961 cgtcaaagtt tgtggaataa actaatattt tattatcgtc tcgaggtgct gctacacctt
     4021 gcgttccata agtgatggaa gcggggaaga catggcctcc attgtaatct gtgtgttcac
     4081 caatcaaatt gatgcgtcct ggtgagaagt attgtgtagt ttttttaggt ccgaatgttt
     4141 cggcaaattt tgtgtttaag cttcttttga tttccatgat gagttattcc tttcttgttt
     4201 tgattttgaa ttctgtcact gtttcaaata ctgatccggc ttttaaatga atcgaaccaa
     4261 atgctgagaa gcgctctgca cctggagctg tttgagtctc aaatgtgatg ccaccgtgat
     4321 gtgccagttt tcggttgcgc atttctggtg tttctgtgcc gaaatttgca gtgaaaataa
     4381 ccacactaga agcatctgta gcaatatcta cttggattct tttatcgggg ctagtcaagc
     4441 gagcggcttc tttacccaag ccggtttctt ttaagaaaaa tggatgatcg attccgtcaa
     4501 caagattttt ttgatccaaa tcactagcaa aaacggacgc taatttttta ggtatttgaa
     4561 aatcgaaagc acttcctgca gcattttctt ttacccctat aggaatacta tctgttcgca
     4621 aaggagcata agcttcgcta ttgagccaaa gctcatgttg atcgattgac tgagaagcat
     4681 ctcccgtcaa gttgaagtaa acatgatttg tcggattgaa taaagtatct tggtcactgg
     4741 tgccgcgaga ggtcactcgc cagatattat cttttgtcaa agtatagcgg atttccacat
     4801 ccattgtacc tggaaaacca tgttctccgt cgggacttgt agtagtaaaa atgacagaag
     4861 cttcattttc gccattcaaa atgacataag accatttttt taattcaaat ccaggagcac
     4921 caccatgcag attatgtcca gtttttggat ctgtggctaa ttggtaagtt tttccattga
     4981 gagaaaagcg gccattttcg attctccctg cggtgcgacc gatagaagca ccgatatacg
     5041 gatctttttc gatatattct tcagcggtgt caaatcccaa aactaattct cgatcatttg
     5101 attttaaact gacgattcta gcacctaaat cagagataga aagtgctagc ttgtttttgt
     5161 tctccaaggt tatcaagtga taaccttggc caaaatcttt ttctgtaatc ttcattttca
     5221 agatcctttc ttaatgggaa ggatctactg catcgtgaag ttcatcttcc attgtatcag
     5281 ctggagccaa tttgttttcc aatttctcaa cgatttgtgc atgttttttc tctgtcaatg
     5341 taatcttcca agcaaaaata atagcggaga aaatcatcaa agcagcagga gcatagaatg
     5401 cataagcttt gaaagtcgtt acgccatgag cagtgatatc agcagcagta gcattaccag
     5461 tcatcccaga agcgatagcg acaaacccta cgatcccgtt agacaaagca ccagcgattt
     5521 tatctagtaa agggcgaatt gatagagtaa cagcttcgtt acggatacca tttttccatt
     5581 gaccatattc aacagagtct gtgatcgtca tcaaagcgga taagaaaatc aattgttgag
     5641 ggaagtagaa caatactagc ccgatgataa cgattggcaa acttgaacct gcgatcgtaa
     5701 agaaaaagta agaagaaatc atcattgcga tccctccaag gtaaacgtag cgacgagaga
     5761 tgacgcgtgt aagcattggg aatagtggaa cagctactaa accaagtaag gcagcaacta
     5821 gaccaacgat ccaaaattca gttggttggc caagtacata tttgaagaag tagaataata
     5881 cggcagttgt tgctgcattg gcaatcgcat aagcgatata agcaagggca agccacatca
     5941 actgatcatt ttgagcaact gctttgaaca catctttgat cccagctttt tcattttgct
     6001 gacggatcgc agtatcgact tcttttgtgc ccaaggcagt gataatcgca gtaccgcctg
     6061 aaataacagc agcaatcaca ccgaaccaga accagcctga agcgccttca atatgtttat
     6121 gagtaacaag ataggtaaag aaagtaacga tagggacaac gactagagta gtaccatttg
     6181 cacctagaga agagccgaaa cgagcaaacg tagcaaattt ttcacgttcc tttgtttccg
     6241 tactcaaagc tggaatcatt gaccaaaaag cgatatcctt aaatgaataa aaactatcca
     6301 ataagatgaa aacgattgca aataatatga taaataaagt cgtattatga gtagctaagc
     6361 caaagaaatt ggtaaagatt gctaccaaga gtacggaact aacaacgccg ccgataacta
     6421 accatggttt gaatttaccg tattttgtac gagtattatc gatgatgcca ccaatcaaag
     6481 gatcaaaaat aatttcaact aagcggatac ctacaactaa gcttgtaact gtagcaatca
     6541 tttttgcatt cgttgcctta tctgttcctg cgaacatctg gcttgtcacg aataccataa
     6601 aataagtgct taatgtaaca tagaatgtgt cgtgtccaaa agcgcctaaa gcgtaggaca
     6661 cacgttggat cattttgctt ttcataatct gtattcctct cctgttcaat atataatact
     6721 aagtaaaccg gttacaacga ataacaaaga tcttttaatg acttaaactt aacaagaaat
     6781 cgcttccttt ttaatatatt tctgtgactt ttatttaact ttttgttgca ttatactaaa
     6841 ggagtaagga gggatagacg tggagcaatc gattttttta aaaaaggaac atcaacaagt
     6901 agaaaaagaa ttgtattttg atttttgtgg tttctctaaa acgatgccgt ttcattcttt
     6961 tggtcctgct attcgcaatg attacatcct gcatgtcgtg atggaaggca aaggatctta
     7021 tcatgtgaaa aatcaacaat tccaattgaa aaaaggtgat ctgttcttga ttcgtccagg
     7081 agactcgacg ttttacttat cagatggaga agatccgtgg atgtattgct ggctttcatt
     7141 tggtgggagt gctgcagaag aaatcattcg gcagtcgctt ttcagagaag accaatacac
     7201 gatggtctct tctgacatac aaaaatatat cgacattatt ttagaatgca tgaaagatac
     7261 ggaagaaacc ttggaaaatg aattacagtt aacagcatta acctaccgtt ttttatcagt
     7321 ccttttaaaa gatggcggaa aggtcagcgg aggtgtacaa aaggttcatt cctctttagc
     7381 tgttgaaaca gtcaaataca tcgaggcaca ttatgctgaa aaattgtctg ttgaggaaat
     7441 cgcccagcat ttagcggtca atcggagcca tttgtcgcga gtattcaaaa atcatatggg
     7501 caccagtatc aaggaatatt tgatcggggt acggatcaat cgaggggcgt ttcttctttc
     7561 tctgacggat gaatccgtgg aaagtattgc ctatcaagta gggttcaata gtctagtcgt
     7621 atttagccga atgttcaaaa agagtaccgg agaaacggct acgaactatc gtaaacgtat
     7681 gaaaaacgaa aattttaaga atattgcttt ggataccttg aaaaaacagt tggaaaaaca
     7741 aaccgcagtt tcttggacaa cctgattagt ctggttaaaa tgacaagcat cggcaaaaga
     7801 aacttgtggc ggttatgcta cactgtaaag cgaagactaa aaaggaggaa aagggatgcg
     7861 tacacttatc atcattagcc atccaacgat cgaagaatct ttaaatcagc aatttttcaa
     7921 agaagcttct gctggtttac cagctacttg gcatcatttg gaatcaagtt atccagacgg
     7981 aaaaatagat atagagactg aactacagct cttggcccag catgatcgga tcattttcca
     8041 gtttccgttt tactggtata gttctcctgc tcatttaaaa atttggcaag ataatgtctt
     8101 ggaacgagca gcacatgtat taaaagggaa agaactagga atcgtattga caacaggtgt
     8161 ggcggaaaaa gaataccaag ctggaggaaa agaagaatat acgatttccg aatttttgag
     8221 gccgtatcag cgaatcgcaa ataaattcca tatgacctat cttccgccat tcgttttagc
     8281 acaatttatg tatttatccc aggaaaaacg ttgggagaag ctaattgctt atcagcagta
     8341 tctctcattg gaaggcaaac catcgctgac tcagcggatt gactggttta ttcaaagagt
     8401 acaggaaaat cagaaaatgc aggaagaaga atctgaaaaa caagcatata tcgtagaagc
     8461 actgactgag gcaaaagagc agatcgaaga cttgaccttt acactgcaag aaatgaaagg
     8521 aacttcatta tgacaaatga ttggctgatc caacaattag atgaattaag cgaaaaatca
     8581 gaatatcaag accgtgcgct cttatatgaa ataaagaaac tgatggctga gatagacgaa
     8641 cgaacaatgc agctgcaagg agaaatcgac ggacaatctt ggaatcatct caactggtga
     8701 aattttctta taaataacaa agataaaaat gtgcacagcg acaattattt gctaaaataa
     8761 gaatatgaag cgtttgataa cgctattata cataaaaatt ggtggtgaaa aaaatgtatg
     8821 atgaaaatga gtggggagaa aatgttcgga tgacccgaag aagacagcaa aaacaggcag
     8881 ctcgtaagcg gatgatcatg attggggcag cagttgccgt gtttttgatc atagcaggag
     8941 gagttgcggg tctatatttt catggaaaaa attcgtcaga agcgaaaagt acgaccataa
     9001 cggaaacaac gacaaagaaa acagagacga aacaaacaag tgagtcatca actaaaacaa
     9061 aagagacaca aacttctgaa gaaaaaacag caaatggttt gccagagcaa cttcaagcaa
     9121 tcgtaaatga ttattcgaaa aagatcgaag aaaagacgcc tgcattgatt gaagaatacc
     9181 agacagaaat tcagggaaat caagagggaa tagctggttt atcagcagtt gctaaccaaa
     9241 aagcacgtga gcttcaagca atctccgacg aagggatcag aaaattacgt gcagcgtatc
     9301 aggcagcaga aaataaagac ggtgtagact tagatacttt gatcaatcaa ttatcggcta
     9361 attatacgaa tcatgtcgct aagatttccg atatttattt gcagactagc gcctctcttc
     9421 aagcagagtc aacaagcaca caagacacaa catcttctga ttctgagaca gcagagtcgg
     9481 tagaagcttc tgaaatgcaa gctcgaacaa cacaagacac aacagattcc tctgaaacta
     9541 ataccaacag cgcgacttca caggctgcga caaccgtagt tttggaagga gaaggtccaa
     9601 atcaaatagc cgaacgaact ggcgtaccag tagaaacgat cttgtcgctg aatgggatga
     9661 gcatggagaa ttatttcctg actcccggtg agacgctaaa attgaattga taaaagcaat
     9721 aaaaaagaac gaagcttcca ctaaggtgaa gcttcgttct ttttttattt tccggttctt
     9781 ttttcgcgta caaagtaatg gatcgtcatg taaagcaaga aaacgagtcc aataatcaat
     9841 gagattctcg tttcaggatt gataaacatg aaaatcaata cgatagctaa aaaagcaagt
     9901 gtcacataat tcgtataagg agatagtggc attttaaaag gatgatcatg cattttatct
     9961 gcgtgcttct ttttgaagcg aatctcgctg atcaaaatca ctacccaagg aaccatacca
    10021 ggcaaaatac ttgagctgta tacgaaaacg aaaatatttt ctgactggtt gatgaacatt
    10081 ggtagaagat aatttaagat cagaccaatt aagattccac ctgagattgc tacgacagga
    10141 taaaaaggcg caccgtgacg agatagtttc agaaattttt tagacatctt tccatttatg
    10201 gcaagtgtat agaccatacg acttgcgctg aaaatccctg aattgcaacc tgataatgcc
    10261 gctgtaatca cgacaaaatt aatcagtcct gcagcaaatg taatgccgac tttagaaaaa
    10321 gtttgtacaa aaggtgaacc aatctcactc aattgattcc acggatagat actcacaatg
    10381 ataaaaatag caccaatata aaaaatcaag attcgaccga tagtggactg gacagcttca
    10441 atgatcgtct ttttaggatt ctctgcttca ccagcagtca ttccgatcag ttcgattcct
    10501 tgataggaag caacaacgat cgataatgca aagaaaaatc ctttgacgcc tccagtgaag
    10561 aatccaccat ttttccaaag atttgaaatc cctactgcct gaccatgatt accaaatcca
    10621 aataagatta ccccaagacc tgcaatgatc atcaaaatga tcgttatgac tttgatgatc
    10681 gaaaaccaaa attctaattc gccaaacgcc ttgacagaaa taagatttgc cagcataaga
    10741 aacaagacga caatgattcc gggaataatt gccggcaaat caggccacca ataattcata
    10801 taagatccta cagcaatcac ttcacttatt cctacgacaa tatattgaaa aatattactc
    10861 caagcggtca agtagccagc cacaggatgg atgtactcgc tcgcgtaatt tgcaaaagaa
    10921 ccagtcgaag gatcaacgta aagcatttcg cctaaagcac gcataatcaa atacaaaaag
    10981 aatcctgcaa tcgcataggc tcccatcact gagggccctg tccaacgtat ggttgaggag
    11041 gcacccataa acagaccgac accgatcgtt ccacctagtg cgatcatttg gatatgacgg
    11101 gcactaagac ttcgagttaa cttttcttct tccatacaaa aactcctttc gttgttgagt
    11161 caacaagaaa aaataatcaa acgtttcaac acatgttttt cattattagg ttagccttat
    11221 tgaactcttg atgtgattct acagaaaatt ttcataaaat gcgaggaaaa ttcgaaaaaa
    11281 actttttcat cattctactt gaaaatgctt tccattttag ttaaactata tttaaataaa
    11341 aagttaggta aacctaaaaa ggagtgtaag atttggaacg tacggccatt gtaattcaag
    11401 acctttcagc cgcttatcaa gggaaaactg ttttgaaaac tatcaacttg acgataaatc
    11461 cacaaaaaat taccggtatt atcggaccaa acggtgcagg aaaatcaaca tttatgaaat
    11521 ctttgctaga gttgatacca gctactactg gtaaagtcac cttttctgga cagccggtaa
    11581 actcagtccg taaaaaaata gcctacgtgg aacagcgaag tgaattggat ctttcctttc
    11641 caattgatgt attaggcgtt gtacttttag gaacatatcc atctttacga attggacaaa
    11701 gacctgggaa aaaagaaaaa gaacgtgcaa gacaagcttt gaaaaaagta gggatggaag
    11761 aatatgccaa aagacagatc agcgaactat cgggtggaca gcttcagaga gtttttattg
    11821 caagagctct agcccaagga gcagaatgga tctttttaga tgaaccattc gtagggattg
    11881 atgcgttaag tgaacgaaag atctttgaca tcttgcagga attgaagaat tcaggaaaaa
    11941 cgattttgat cgtccatcat gatcttcata aagtagaaga atatttcgat gaggttattc
    12001 ttttaaataa acagctgatc gccttccggt ccagtacaag aagtctttac atcgaagaac
    12061 cttcaattgg cctatggtga gatcatcaga catttagtaa aaggaggaga gaaaaaatga
    12121 tccaatcctt tattgatgga ttaatgaatt atcaattcct gcaatacgct ttggtcactt
    12181 ccatgcttgt aggacttgct tctggagtca tcggttcttt tattatttta cgagggatgt
    12241 ctttgatggg agacgctatc tctcacgcag ttcttccagg tgtagccatt tcttatatgt
    12301 ttggttttag ttacatcttt ggagccactg cttttgggat gctaacagca gcagtgattg
    12361 gtttcgtgac tcagcggagc cgattgaaaa atgatacagc gattggaatt gtctttagct
    12421 ccttttttgc attagggatt atcttgattt catatgccca gagtgcgaca gatttgtatc
    12481 atattttatt tgggaatgtc ttagctgtta gggaaagcga tttgttgctg acagcactcg
    12541 ttagtggaat cgtcttgata tttgtctttt tcttttataa agaattgaag atcacatcat
    12601 tcgatccgac aatggcaaaa gcttatgggc tgaacacatc gctgatccat tatcttttga
    12661 tgttcttttt gacattagtg gctgtagtca gtttacagac agtaggaaca atcttggtga
    12721 ttgccatgtt gatcacacca gccgccacgg cttacttgct aacgaaccat ttactgaaaa
    12781 tgatcattac agctgcagga atcggtatgc taagtgcagt tgtcggtgtg tttttcagtt
    12841 atagttacaa ttggccatca ggagctacga tcgtgttagc atgtaccgca ttttttatcc
    12901 ttgctttttt attttctcca acaaaaggaa ttttatttca gaaaggaagc agatagatga
    12961 aaacaaaaaa atcactcttt ttaatcttgg cagttagttt cttggtatta gccggttgcg
    13021 gaaagcaggc ttctgaccaa gcggatgaag gaagtaaaga aaagttgtca gtcgtggcta
    13081 ccaattcgat cttggcggac atggcaaaag aggtcggaac agatcaaata gatatccaca
    13141 gtatcgtacc agtcggaaca gatccgcatg aatatgaagt actaccagaa gacatcaaaa
    13201 aggcaagcga tgcagatgtt attttataca acggtttgaa tcttgaaaca ggtaacagct
    13261 ggttcgataa cttgatggaa acggctaaaa aagaagaagg aaaagattat tttgcagtta
    13321 gcaaaaatgt agaacctctt tatttaacta gcggtgaaga acatacaaaa gcagatcccc
    13381 atgcttggct agacctatct aacggaataa aatatgtgga ggaaatcgca cgtatattct
    13441 ctgaaaaaga tgcagaaaat gcgacactct ataaaaaaaa tgcagaagca tatgtggaaa
    13501 aactaaaaga attagataca caagcgaagg aaagttttgc ttctatcgaa gagaacaaaa
    13561 aattattagt aacaagtgaa ggggcattca agtatttttc acgagcatat gatttgccag
    13621 cagcttatat atgggagatc aatacagaaa gtcaaggtac gcctgatcaa atgaaagcga
    13681 tcattgatca gataagagca aaagaagtac cggttttatt cgtggaaacc agtgtagact
    13741 caagaagcat ggaacgggta gcaaaagaaa cgggtttgaa aatctatgat aaactgttca
    13801 ctgattccat agcaaaagaa ggagaacaag gagattctta ctatcagatg atgaaatgga
    13861 atattgaaac gatccatgaa ggtttgtcac aaacaaaaga aagctgaaaa gtgcaaggtc
    13921 tagcttgagg agcagacctt gcatttttta taagagatat gaaaaaaaat tatgctgttt
    13981 ttcgtcgtac agataccttt tttgaagaaa ttccgttata gttagagtaa ggaaggaagg
    14041 tgtggctatg aattttacac gtaaagataa atatacgatt aaagaagaag tctttcgatt
    14101 gatcagccag caggaaaata ccgacaagga tcaagacctt caatttcttg aagcagaatt
    14161 agctaaatta ttcatagcaa atcaaaatga gacaacagaa ccagatgaag agctgtacat
    14221 aggcaaatgg ttgtttgatg aatttcagcc tttagatgaa aataccggta tcggttattt
    14281 tgtgttcctt tctccagtcg gcttcacacc tggcgtatta gttaaacaaa acgacgaaat
    14341 aaccgtcaaa gcatggcctg cattattttc agtcatcaaa gcagaaggag taatcaaaaa
    14401 gatccagtcg gcctattata aaagtcaatt tattgccaac agcaaattaa tgaatatgtt
    14461 ttataatcgt ctagtagaaa ttgctaggcc tgggaaaatc ccgcaaacat tcacgtacac
    14521 acagcaaaaa aatctctatg aagaagtatt gtattcccgc gatctgtctg agttttcgcc
    14581 atgggaagag gtaaggctcc atgaactgtt aagtacaaaa ccagtttcat tgaatttttt
    14641 taatgcatta gataacaaaa gaaaattaat ttcaacaaat tattgggaag tatttgctgc
    14701 aagaaaaaaa tggatggaag aaaagaagat tgccgatcag cagatccagt ttgtccagct
    14761 gaaaaaagaa aaactatatt atgggttata cagccgttaa cagcaagcga ggaagaccat
    14821 gacattaaaa gaagaaatca tacaagaaag caaacgatta ggaattgaca aaatcgggtt
    14881 caccacggcg gaaccttttg attcattaaa agaatcgttg gaagaacaaa aagcagctgg
    14941 ccatacttct ggctttgaac atccaaatat cgatgagcgt ctttatccag aaatgacatt
    15001 tgatcagccg aaatcgatca tttccattgc acttgcgtat cctactagga tccatgaaga
    15061 agtgcctagg gatgaaaaac gcgggcagtt tgctcgtgct tcttggggga tcgattacca
    15121 tgatatactc agagaccgtt tgaaccgatt gatcgaattc atccaaacaa gagcagaaaa
    15181 atggcaaaaa gaagaggaat ggcgtctagc tccgcaagta gatactggag aactgatcga
    15241 tgtcgctgta gcacagcgag ctggtttagg atttattgga cgaaacggat tgttgatcac
    15301 tgaagagttc ggttcatttg tctatcttgg tgagatcgtt actaatattg tatttgagcc
    15361 tgataaacca ggagaatttg gttgcggtga ctgtatgcgc tgcgtgactg cttgtccgac
    15421 aaaagcattg cttggtgacg gaagaatgaa tgcccagcga tgtttgtctt atcaaactca
    15481 gacaaaaggg atgatgccgg aagaatatcg taaaaaaatg cgaaatgtca tttatggatg
    15541 tgatatctgc cagttagtct gcccttacaa tcaaggaaaa gattttcatt ttcatgaaga
    15601 gatggaacca aaagtagacg aaatatatcc aaaattaaag ccaatgcttt cgatgtctaa
    15661 taaagacttc aaacagcaat ttgggcattt agctggttca tggcgtggga agaaaccttt
    15721 gcagagaaac gcattgattg ctttagctaa tctaggtgat cgaacggcat tgcctgagat
    15781 ttcagaatgt ttaacagatg tccgccctgt catcagagga acagcagctt gggctattgg
    15841 acgtctagga acaaaagaac cggaaaaatg gcttgatgta ttagatgaaa tattagctaa
    15901 agaaacagaa gaagtcgtta taaacgaatt ggaacatgcc cagaaattat tgcggagaaa
    15961 gttaaaataa aaaaatagtt aacattattc aaagtttttg tccagtaatt gttgtaacaa
    16021 ttactggttt ttttg
//
LOCUS       DAJSMK010000052        15963 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.054, whole genome shotgun sequence.
ACCESSION   DAJSMK010000052 DAJSMK010000000
VERSION     DAJSMK010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15963
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.054"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            292..1431
                     /locus_tag="ON488_001724"
     CDS             292..1431
                     /locus_tag="ON488_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HCR3231919.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1498..2073)
                     /locus_tag="ON488_001725"
     CDS             complement(1498..2073)
                     /locus_tag="ON488_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HCR3231920.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2078..3052)
                     /locus_tag="ON488_001726"
     CDS             complement(2078..3052)
                     /locus_tag="ON488_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HCR3231921.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3076..3120)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3328..4296
                     /locus_tag="ON488_001727"
     CDS             3328..4296
                     /locus_tag="ON488_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3231922.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4409..4687
                     /locus_tag="ON488_001728"
     CDS             4409..4687
                     /locus_tag="ON488_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HCR3231923.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4805..5041
                     /gene="secG"
                     /locus_tag="ON488_001729"
     CDS             4805..5041
                     /gene="secG"
                     /locus_tag="ON488_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HCR3231924.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5144..5899
                     /locus_tag="ON488_001730"
     CDS             5144..5899
                     /locus_tag="ON488_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3231925.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5902..8259
                     /gene="rnr"
                     /locus_tag="ON488_001731"
     CDS             5902..8259
                     /gene="rnr"
                     /locus_tag="ON488_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HCR3231926.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8281..8745
                     /gene="smpB"
                     /locus_tag="ON488_001732"
     CDS             8281..8745
                     /gene="smpB"
                     /locus_tag="ON488_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HCR3231927.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9047..9766
                     /gene="atpB"
                     /locus_tag="ON488_001733"
     CDS             9047..9766
                     /gene="atpB"
                     /locus_tag="ON488_001733"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HCR3231928.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9819..10034
                     /gene="atpE"
                     /locus_tag="ON488_001734"
     CDS             9819..10034
                     /gene="atpE"
                     /locus_tag="ON488_001734"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HCR3231929.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10125..10649
                     /gene="atpF"
                     /locus_tag="ON488_001735"
     CDS             10125..10649
                     /gene="atpF"
                     /locus_tag="ON488_001735"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HCR3231930.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10636..11178
                     /locus_tag="ON488_001736"
     CDS             10636..11178
                     /locus_tag="ON488_001736"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HCR3231931.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11201..12757
                     /locus_tag="ON488_001737"
     CDS             11201..12757
                     /locus_tag="ON488_001737"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HCR3231932.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12771..13673
                     /locus_tag="ON488_001738"
     CDS             12771..13673
                     /locus_tag="ON488_001738"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HCR3231933.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13696..15102
                     /gene="atpD"
                     /locus_tag="ON488_001739"
     CDS             13696..15102
                     /gene="atpD"
                     /locus_tag="ON488_001739"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HCR3231934.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15116..15538
                     /locus_tag="ON488_001740"
     CDS             15116..15538
                     /locus_tag="ON488_001740"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HCR3231935.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         5269 a         2879 c         3445 g         4370 t
ORIGIN      
        1 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
       61 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
      121 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
      181 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
      241 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
      301 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
      361 ggtgaagtag cagcctattt gaataagctt ttggcaaggc atgacataac aggagagatt
      421 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
      481 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
      541 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
      601 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
      661 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
      721 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
      781 gagccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
      841 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
      901 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
      961 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
     1021 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
     1081 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
     1141 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
     1201 cctttgattc attccattca gcaacaattc agccagccat tacctttagt tggagcggca
     1261 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
     1321 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
     1381 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
     1441 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
     1501 gcctattttt ctttttgaat atatcaagcg ttggggcaac atagtgatga ctaatgaaac
     1561 aacgacgata gacaacaagc gatcaaggta gtctgtaccc acctgtacca agatcacact
     1621 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
     1681 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
     1741 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
     1801 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
     1861 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
     1921 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
     1981 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
     2041 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
     2101 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
     2161 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
     2221 aacgatcaac caatgtttgt ccgcgactta ttccttgagt ttctacagca gtgaagcttt
     2281 taaagccttc acagatggac tcatcgataa aataagcaac agctaatgga tcattgatga
     2341 cacatcctaa gattctttct tgtttccagt gaaagtcaaa ataaaaacga gtgatcgctt
     2401 ttagatactc tccctcttca ggattcattt ggcagcaata ttcaaggata gtcggtgtca
     2461 agacgatttc tcttgtcaca tctaacccaa ccatttctat cggttgtttg agcttttcga
     2521 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggtgaacagt
     2581 taccatggct tttgtaagtt ccgcccattg agacaaaacg atccatatgt ttcccaacag
     2641 atgggctgtt tttcaaagca gaagcgatat tggtcaaagg ccccaaagca atgactgatg
     2701 tatctgtttt ttctttgaaa taatcagtca gaaaatcaac tgcatggagc gattctgcct
     2761 gtttggctaa gaccatcggg aaatttgtgt cccctaatcc atccaaccca tgagtgtctt
     2821 gcgcactaat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca gggatatcta
     2881 aacgatcaca gcgctccaaa catttcagca cattctgcgt accgatatct acagggacat
     2941 tcccgcaaac gacggtaata gcaactactt cgatatcagg ggatttgaca gctagtgata
     3001 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tactttacgc attatttcca
     3061 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     3121 acgagtgtct tgtttataat gcacgaaatt agtatactgg cttttattgt gaatgtaaat
     3181 gctctcttac aagtaaatct attgagaaga actaatgata caatgaaaaa gaaatggaat
     3241 ttacgtgtgc cgaagaaaaa gaatcctatt gatcggtata ttgtataata aatagattat
     3301 agtttggcag aaagcggcgg gtgtacgatg gttatttttt atttcattct tattctgata
     3361 tttataggaa tcagttacca ttttctttct tatttttatg caaagaaatt agtaagagcg
     3421 ggggtacaga gaggctatga ctggtatgaa gaaactgggc accgcttgat ggatcctgct
     3481 gcagtcacgt cagtagaaaa aaagcgacaa aaattagaag aagagtgtga aagcttctgg
     3541 gaacaaggaa taccgaaaac gatcaaaagt tatgacgggt tgaaactagc tggacagatg
     3601 ttcctccaac caactcagca gaataaatgg gtcatttgtg tacatgatta tcgaagtaca
     3661 gggaaaagag atatgtctca tataggtaaa agatatgcag agaaaggatt caacgttctt
     3721 atacccgatt tacgtgcgca tggagaaagt gaaggagaaa tcatcggaat gggatggcta
     3781 gaccggctag atttaattgc atggatccaa ctcatcttag atgaacaacc agatgcatcc
     3841 attattttgc acggcagttc gatgggcgct tctactatta tgatggcaag tggtgaaaag
     3901 cttccatctg cagtcaaagg atttatctta gacagcggat atgtttctgt ttatgcggaa
     3961 tttcggtata tgttaagtaa aatcacggtc tttcctaaaa aaatgatcat gagatatgcg
     4021 aatcactatg ctcagaaata cgcaggttat tctttaaagc aagcatcagc tacaagacag
     4081 cttggtagta accatttgcc tttgttagtc atccatggtg aaagagatca ttttgttcct
     4141 acagaagcag catacacgat tcaaaacgct acggcagggg ataaagcatt actgcttgtt
     4201 ccagaagcag aacatttgga agcatcgatg aaagatccga aaacctattg gacagtgatt
     4261 ttttcattta ttgaacaaag aataacgatg gattgatttt ctcttccttt ttgtaagcaa
     4321 cacgaggata aataattgtt tatagaccat gagactgtta aaataaggta ggaataaaaa
     4381 aatatcagtt atttgaggag tgcggcatat ggaaatcaaa gaggaaaaaa atcgtcttgc
     4441 tttattcaat gatgagcaac aagaaatcgg agaaatgaca tggtcggatg cggggccaga
     4501 catcatgatc attgaccata catttgtcga tccagcatat cgtggtcaaa aattagctga
     4561 aaagctagtg tatactggag tagaactagc aagacgagag gggaaaaaga ttatcccttc
     4621 atgcccttac gcaaaaaaag agtttgagaa gaaaccagag tatcatgacg tcttacgcca
     4681 atcataataa taacagctga aagatttgca ctttcagctg tttttccatt tatatagagt
     4741 tgtcacggag ttttatctat gataaagtta aagagacgat atcttttggg aaggaggctg
     4801 ctatatgtat aatttaattt tgggaatcgt gatcgtttta tcgattgtta tggtcattgc
     4861 gattatgatg cagccaagca agcaaaatag tgcagcgagt gcatttaccg gcggtgcgga
     4921 tcaactattc ggcaaacaaa aagctcgcgg ctttgaagct gtcatgcagc gatcaactgc
     4981 agtcatggga gctgtctgga tgatcttatt atttgtccta gcatttttat cttcgaagta
     5041 gtcgaataag cctctcgcac aacggcgggc ggcttttttt attgcaaaga gaacgcttaa
     5101 gaagaagtta tgaaagaaac tatggtaaaa tgaggcgaaa gaggtgaaac gagtgaaaca
     5161 attaccaaaa cccctttatg caaaacatgg aaaacgagca gttttgctgc ttcatgcgta
     5221 ctcaggaagt ccaaatgatg tccggatgct cgcacggttt ttagaaaaag cagattatac
     5281 agtctatgcg ccgctattta aaggacatgg aacgatggag ccatatgata tcttgcaaga
     5341 aaaagcagaa agctggtggg cagatactaa aaaagctatc cattttttac agtctgaaca
     5401 gttttctgat attgccgtat tgggattatc gatgggtggc atctttgctg tacgggcact
     5461 agaagaagaa tcagtaattg gcggcggttt tttctgttcg cccctgtctc ctgtagaaac
     5521 aaacgtgcct gaaaattttg aaaaatatgt acgtcaagtg ctgaagatag caggcaaatc
     5581 agaaaaagaa atcaatgaaa aagctgtgtc ttaccgctcg ttagctgaac atcaattaat
     5641 ggatatacaa gaccaagcag caatcgcaga aagtagacta tcagatatcc aacagccaat
     5701 atttttagct caagctggga aagatgaaat gatcgaccca aatggtgtat ttgaaacggc
     5761 acgcaaattg agccgccaac gagtgacact tcaatggtat cctgaaagcg gtcatgtgat
     5821 tacagttggc acagcaagac gcgaattaga aaaagacgtg ttggaatttt tagaaaaatt
     5881 accttggaat gaggaataaa tatgacaaaa gaaacaataa aagagaaaat tctctttttc
     5941 atggaaagca gtcgcaaacg tagtttttct atggaagaaa tcgctgaagg tctaggcttt
     6001 caaaaaagcg atgattttaa attactagta caaacgattg ctcaaatgga aagagaacag
     6061 agtatcgttt tcaataaaaa aggaaaagtc aaacttcctt taaaaccgat cttggtcgaa
     6121 gggacatttc gggcaaatga acgaggattt ggatttgtaa cgattgatcc cgaagaagat
     6181 gatatctata tcccgaaaga agcgactggc tttgcaatgg atggggatac cgtagcaatt
     6241 gatatcatga agcgagcaaa tacagatatg gatcgcggag cagagggaaa agtagtggag
     6301 attcgagacc gagcgactac tcagttagcc ggagaatttg ttgcttattc agacgaagag
     6361 atacaggaaa cggatcttta tggtgtggtc atcccgaaag atagaaagct taaccaattc
     6421 aaagtgtatg cagcggcaga gggagttcgt ccagttgacg gaagtattgt attgatcgaa
     6481 ctgacccatt accctgaaaa agggtatgca actagtttag aagggataat caagcaagtg
     6541 attggtcata agaatgaccc tggcatggat atcctctcga ttgtcgtggc taacggtatt
     6601 cctacaaaat ttcctgatga tgtgttatct gaggcagatg aagttccaga ccagatcagc
     6661 gaaaaggata ttgttggacg cagagattta agagatcagc tcatcgttac gattgatgga
     6721 gaagatgcaa aagatctaga tgatgcagtg acggtcaaaa aattagaaaa tggtaattat
     6781 tttcttggag tacacattgc agatgtatct tactatgtga cgcaaggcag tcaactggac
     6841 agagaagcat acgaaagagg aacaagtgtc tatttgaccg atcgagtgat tccgatgatc
     6901 ccacaacgtt tatccaatgg tatctgttca ttgaatcccc atgttccacg actcaccatg
     6961 agttgtgaaa tggagatcga tccaaatgga caagttgtct ctcatgagat ttttccaagt
     7021 gtgatccaaa caacagaacg gatgacctac acagctgtca atcaaatctt agaagatcaa
     7081 gatgaagaaa cgatgcaacg ttatgctcag ctcgtgccta tgttccaaga aatgggtgaa
     7141 ttgcatcgaa tccttgaaat gatgcgaatc aaacgtggag cgatttcttt tgaggatcgt
     7201 gaagcgaaga tccttgttga tgctgaagga cacccaaatg atatccagct aagaagcaga
     7261 gggataggtg aacgcttgat cgaatccttt atgcttgctg ccaacgaaac ggtagctgaa
     7321 cattataata aattaaatct tccgtttatt tatcgaatcc atgaacagcc aaaagaagaa
     7381 aaaatgcagc gcttctttga ttttgcttca gctttgggca ttctggtccg aggaacgaaa
     7441 ggaacgatca caccaaaaga tttacagcat gtgatcgaag gagtagaaga caaaccagaa
     7501 gctgcagtta tcaatactat gttgctaaga agcatgcaac aagcacgcta ttcagaagac
     7561 aattttgggc attatggctt agcggcagat tactacacac actttacatc tcctattcga
     7621 cgctatcccg atctaatcgt ccatcgtctg atccgttctt acagtgaaga taaaagtgaa
     7681 agcaatcaaa gttcgtgggc tgcggaactt cctgaaattg cagatcatag ttctaagatg
     7741 gaacgtcgtg cagtagaaac agaacgtgaa gtagattcca tgaagaaagc agaattcatg
     7801 atggacaaag tgggagaaga attcgatggg atcatcagct ctgttgtgaa attcggcctg
     7861 tttatcgaac tgccgaatac agtagaagga ttgatccata tcaatgaatt gaaacaggac
     7921 tacttccatt ttgttgaaaa tcatttagct cttgtaggtg aaagaactgg tctgactttt
     7981 aaaatcggac aaaaagtgcg cgtaaaagta gtcaaagctg atccagatga acgagcagtg
     8041 gattttgaac tcgtttccgc agaagaggtc actgcgttgg aacgtccaaa agcacgcaat
     8101 ggaaaatctg gaaaacgaga aggaaaacaa gcaggcaaac gctcagaaaa aaatggcaag
     8161 aagaacaaac gatatagtga tagtaagcaa acgttcggta agaaaaaagg gaaaaagcca
     8221 ttttacaaag gtgtcaaaaa gaagaaaaag aaaaaataaa atgagttgga ggaaacagct
     8281 atgccaaaag gcgagggaaa actaattgca caaaacaaga aagctcgcca tgattattcg
     8341 atcatcgaca cgatggaagc agggatggtc ttgcaaggaa cggagatcaa gtcgatacga
     8401 aacagccgga tcaatctgaa agatggattt attcgcgtcc gcaacgggga agctttcttg
     8461 cataatgttc atatcagtcc ttatgaacaa ggaaatattt ttaatcatga tccgttgcgc
     8521 acgagaaagt tattattaca caagaaacaa atcgttcgtc ttgaaaacga attgaaaaac
     8581 actggaatca ctgttgttcc tttaaaagtc tatattcgta acggctatgc caaggtattg
     8641 attggtctgg caaaagggaa aaaatcgtat gataaacggg aagatttgaa acgaaaagat
     8701 atcgatcgac aaattgatcg aacattaaaa aatttctcta gataatttca ttatcctttt
     8761 tcgcatattc ggtgcttttg cttttactta atgataaaat ttgttagcat ttaatctgat
     8821 aaaacatgat tatcacaggt tttttcttag atcaggagca ccgtgcatgg ggaaaaattc
     8881 gcttcgtttt tgactgaaat aaaaaagtgt ctaattttca tgaaaatgtt ttgaattttc
     8941 tgtttcatgg tggtatgata ccgtgtggtt agaaaccgat tggaaaaaac cagatacgca
     9001 catgaattga ttttatgtga atttcgggga aaagaggtga aatggattgg atgaacgctc
     9061 gctaacgttt cacattggac caatttggtt tgatggtaca gtttgtataa tggtgttact
     9121 gacctgtttg attgttttct tcttagctta cttttttaca agaaatctta agttgaaacc
     9181 aacaggcaaa caaaatgcga tagaatgggt cattgatttt agtcgaggaa tcgtaacaga
     9241 taatctgcct agaaaagaat tgagcaattt ccatttgttg gcatttacat tgtttttatt
     9301 tgtttttgtt gcaaacaaca taggtttagt aacaaaaatc gtcttaccta acgaaacaac
     9361 actttggaaa agcccgacag cagacccgtt tgttacttta actttggcat ttataatgat
     9421 cttacttact cacttattcg gggtgaaaaa gttaggcttc aaaggatatt tcgtaaattc
     9481 gttcttgaaa ccctatagtt ttatgtttcc gatgaaactg attgaagaat ttacaaactt
     9541 attaacactt gctttacgtc tttatgggaa tatttatgcg ggggaagttt tgctaacctt
     9601 gattgcaaaa atgatgacaa gcttaggctg gttctcatta ccattagcaa ttccattaga
     9661 gatggtctgg atcgcgttct ccttgtttat tgggagcatc caagcatttg tctttgtcac
     9721 tttgtcaatg gtttatatga gccataagat tgaagtagaa gaataatact cggttaaaaa
     9781 acaaactact atttatctat tttaggagga aaacaattat gaattatatc gcagcagcaa
     9841 tcgcaatcat gggagcagca atcggagccg gttatggtaa cggtcaagtt atctctaaaa
     9901 caatcgaatc aatggctcgc caacctgaaa tgtctggtca attccgtaca acaatgttta
     9961 tcggggtagc tctagttgaa gctgttccta tcttaggggt agttatcgcc ttgattctag
    10021 tttttgccgt ttaattgaat cagtattaag gcagaaacaa catcgtttgt tactgctttt
    10081 ttacatggaa actagaaata ctccaaagaa aggaaggctc gcctatgctg aatcaattgg
    10141 caattgcaga agttggcaat gcgatgttag gtaatatcat cgttgtcagc ggctcatttt
    10201 tgatactact ggctctcttg aagcactttg cttggggacc aatcagcgat attttgaaaa
    10261 aacgtgaaga caagatcgcc aatgatttag attctgcaga acaatctcgc atcaactcag
    10321 cgaaaatgga acaagaacgc gaacaacaat tgttagcctc tcgttctgat gcagctgata
    10381 tcatcaaaaa tgcgaaagaa agtggagaat taagccgcca aaatattttg aaggatgctc
    10441 aagaagaagc agctcgtcta aaaagcaaag cccaagctga tatcactgta gaacgtgatt
    10501 cagcgctgaa ctctgtaaaa gacgacgttg cagaactctc tcttcaaatc gcggaaaaaa
    10561 tcttgaacaa agaattatct ccagaaatgc atgaatcatt aatcaatcaa tacattgaag
    10621 gtctaggttc ttcaaatgaa actagataaa tatacagtag gaagacgtta cgggaaagct
    10681 ttatttgaac tggcgatcga ttcaaatcaa gcagaagaaa tctatcaaga tctcgtaagt
    10741 ttacgtcaaa tctatgaaca agtacctgga ttagggaata tgttaagtga tgttcgtcta
    10801 gaacctcatg aaaaacgaga aatcatggac aagcttgtca gcggttatga tggaatcgtt
    10861 aaaaactttt tagaagttgt ttatgagtat aaccgaatgg atgacctttt gttcatgatt
    10921 gaagaatatg aacgtcgata tgatgaacat caagggttac tattgggaag tgtcacaaca
    10981 gcagtcccac tttcagacga acaacgaata caattagaaa agaatgttgc aaaaacaatg
    11041 gactatcaat cagttgaatt aaaacaaatc gttgattctt ctattattgg tggcgcgatt
    11101 gttgaagcca accatcgagt aatcgacgga agcattcgca cgcaattaga aaaaatgcgt
    11161 aatcaattaa acagatagta caaagaggta ggtgaatcga atggccatca aagcagaaga
    11221 aattagtgcc ttgattaaag aacaaattga aaattatcaa aacgtgcttt cagtcgaaga
    11281 aatcggtacc gtaacttatg taggtgacgg gatcgctcgt gcacatggtt tagaaaacgc
    11341 gatgagtggt gagttgcttg aattttcaaa cggctcatac ggaatggcgc aaaacttaga
    11401 gtcaaatgat gtaggtatca ttatccttgg cgatttcgag tccattcgtg aaggagataa
    11461 agtaaaacga acaggtaaga tcatggaagt tccagttgga gaggccttga tcggtcgggt
    11521 agtcaatccg ctaggtcaac caatcgacgg actaggtgaa atcgttactg acaaagctcg
    11581 tccagtagaa gcgatggcac caggtgttat gcaacgtaaa tctgttaacg aaccaatgca
    11641 aacagggcta aaagcgatcg acgcccttgt gccaatcgga cgcggacaac gtgaattagt
    11701 catcggtgac cgtaaaacag ggaaaacttc tattgcgatt gatacgatca tcaaccaaaa
    11761 aggtcaagat atgatctgta tctatgtagc aatcggacaa aaagattcta cagttcgtac
    11821 acaagttgaa acattgaaaa aatatggcgc aatggattac acaatcgttg tgaatgccgg
    11881 tgcgtctcaa ccagcaccat tactttatat cgcaccatat gctggtactg caatgggtga
    11941 agaattcatg tacaacggta aacatgtatt gatcattttt gatgatcttt caaaacaagc
    12001 tgttgcttat cgtgaacttt ccttgctact tcgccgtcca ccaggtcgtg aagcttatcc
    12061 tggggatgtt ttctacttgc actcacgttt attagaacgt gcagcaaaat taagtgatga
    12121 tctaggcggc ggttcaatga ctgctttgcc atttgttgaa acacaagctg gagatatctc
    12181 tgcttatatc ccaacaaacg ttatctcaat cactgacgga caaatcttct tagaaagcga
    12241 cttgttctac gcgggtactc gtccagcggt tgatgccgga ctatctgtct ctcgtgtagg
    12301 gggttctgcg caaatcaaag caatgaaaaa agttgctggg actttacgtc tagacttagc
    12361 aagttatcgt gaattagaag catttacaca attcggttct gatttggatg cggcaacaca
    12421 agcaaaacta aatcgtggac gccgtacagt agaaatcttg aaacaaaaac tgcatgcacc
    12481 gctagctgtt gagaaacaag tagtgatttt gtatgccttg acacatggat tcttggacag
    12541 tatccctgta gacagtattt tagacttcga acatgaatta ttcgaatatc tggataccaa
    12601 tcattcagat atttttgaaa caatccgtac aacaaaagat cttccagaag aagaaacgtt
    12661 gaacagtgcg attcaggaat ataaagacat gttcttagct acaaaaggaa ataattcctc
    12721 tacagaagat aaattgaaat ccattcaaaa tgcatagtga ggtgagatga atgggtgctt
    12781 cattaaatga aatcaagaca cgtatcgctt caacgaaaaa aacgagccaa atcacgcggg
    12841 caatgcagat ggtgtctgct tctaagttga caaaatctga agcttcttca cagaagtttc
    12901 aggtttatgc aacaaaagta agagaaatcg ttacgcattt gactgctact cagttaaatg
    12961 atattgcctc agaaaatcct agaggggata tcaattacaa cagcatgctg ctcagccgtc
    13021 ctgtgaagaa aaccggttat atcgtcatca ctgcagatgg cggtctggtc ggtggatata
    13081 acagttcgat attgaaacaa acgatgtcta ttttagaaga agaccaccaa tcacccgatg
    13141 attacgtgat gatcgcaatt ggcggaactg gtgcagactt ctttaaagca cgcggtatca
    13201 acctagcata tgagctgcgc aatttatctg atcagccaag ctttgatgaa gtccgcaaaa
    13261 tcgtaaatat ggcaacaact atgtaccaaa acgaagtatt cgatgaatta tacgtatgtt
    13321 ataaccatca tatcaattcg ctaactagtc agtttcgtgt agaaaaaatg ctgccaatct
    13381 cagacttaga tccagaagaa gcaacgactt tcgaacaaga atatattttt gaaccttcaa
    13441 aagaagaaat cttgtctcag ttattgcctc agtatgctga aagtttgatc tacggtgcga
    13501 tcgttgacgc caaaacagca gaacatgctg ctggtatgac agcaatgaaa acagcaactg
    13561 ataatgctgc taatatcatt gatgagctga cggtttctta taaccgtgca agacaagggg
    13621 ctattaccca agaaattacc gaaattgttg ccggagcttc ggcactagaa tagtattgag
    13681 attggaggaa aaaagatgag ttcaggcaag attgttcaag taatcggtcc cgttgtcgac
    13741 gtggaatttt ctttagacca atccttacca gatatcaaca acgcattagt tgtttataaa
    13801 aatgacgaaa ataaatcaaa agttgttctt gaagcagcgt tagaattagg ggacggagtg
    13861 atccggacca ttgcgatgga atcaacagat ggtttacaaa gaggaatgga agtcattgat
    13921 acaggcaaag caatctctgt tcctgtaggt aaagaaacat taggtcgcgt attcaacgta
    13981 ctaggagata cgatcgattt agaaacacct ttcccagaag atgcggaaag aagcgaaatt
    14041 cataaaaaag caccagcctt tgacgaatta agtacaagta cagaaatttt ggaaacaggg
    14101 atcaaagtta tcgatttgct tgccccatat ttaaaaggtg ggaaagtcgg actattcggt
    14161 ggtgccggtg ttggtaaaac cgtactgatc caagaactga tccataatat cgcccaagaa
    14221 catggtggta tttctgtatt taccggtgta ggtgaacgta ctcgtgaagg taatgacttg
    14281 tattatgaaa tgaaagattc aggagttatc gaaaaaacag ccatggtgtt cggacaaatg
    14341 aacgaaccac caggtgcacg tatgcgtgtt gctttgactg gtttgacgat tgcggaatat
    14401 ttccgtgatg tagaaggtca agatgtactg ttgtttatcg acaacatttt ccgtttcact
    14461 caagctggat ctgaagtatc agccttgtta ggacggatgc cttctgcggt tggttatcaa
    14521 ccaacattgg caacagaaat gggtcaattg caagaacgta tcacatctac gaaaaaaggt
    14581 tcgatcacat cgatccaagc aatctatgtg ccagccgatg actacactga cccggcgccg
    14641 gcaacagcat tcgcccattt ggatgcgaca accaacttgg aacgtaaatt aacagaacaa
    14701 gggatttatc cagcggtaga tccattggct tcttcttcaa gtgctttagc acctgaaatc
    14761 gtgggagaag aacattataa agtagcaaca gaagtccaac acgtattgca acgatatcgt
    14821 gaattacaag atatcattgc tatcttaggt atggatgaat tatccgatca agaaaaagtg
    14881 ttagtttctc gtgcccgcag agtccaattc ttcttgtcac aaaactttaa cgtggctgaa
    14941 caatttactg gtcttccagg ttcatatgtc cctgtagaag aaacagtgaa aggattccgc
    15001 gaaatcttgg aaggcaaata cgatgatctt cctgaagaag ctttccgaag tgttggccga
    15061 atcgaagacg tcgtagaaaa agcgaaaaca ctaggctact agaaaggggt gccccatgga
    15121 tcaatattta acagtaaatg tggtaactcc tgccggtttg gtctatgatc accatgcagc
    15181 tatcgtcgtt gcacgtacga cagctggtga gcttgggatt ttgcctaaac atgcaccaat
    15241 catcgttcca ttgacgattg atgaagttcg tgtaaaacga acagattcag atacccacgt
    15301 cgattggatc gctgttaatg gcggaatcat ggaagttcgt gataatgttg tttcaatcgt
    15361 tgctgatagt gcggaacgtg aacgtgatat cgatgtatct cgtgcggaac gtgcaaaaca
    15421 acgcgcagaa cgccaaatcg aagaagcaaa agcaaaacaa gatacgaacg aattgaaacg
    15481 ggcaactgtt gcgttgcacc gagcaatcaa tcgtatcaaa gtatctaagc actcataaaa
    15541 tgagatgcgg atgtttatcc gtgtttaaga acagtaaaaa gaggttatga cagaagtggt
    15601 cagcttcaag acataagaag gaatttacga aaattgcttc tcaaattttt gtgaaatctc
    15661 agcttatttt tcgaagaagc tacttctgga acaccgtata tcagaggttg tgaaatcagc
    15721 gttttgtcct gagtattaga gaaacaaatg gaaaatagtt cctcatattt tgccgttttt
    15781 tgagctaata ccgagggtca gatgattgaa caccgtttat ttggaataag ggactgcgac
    15841 aagacttttg tctcagtccc tttttttgca tatttttagc atttatttcc taaaaaatgt
    15901 aaggggattc ctatattttt aagtatactt gtttttcctt ttatacattt tatggtatta
    15961 tca
//
LOCUS       DAJSMK010000053        15344 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.055, whole genome shotgun sequence.
ACCESSION   DAJSMK010000053 DAJSMK010000000
VERSION     DAJSMK010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15344
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.055"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(56..358)
                     /locus_tag="ON488_001741"
     CDS             complement(56..358)
                     /locus_tag="ON488_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231936.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(578..944)
                     /gene="ssrA"
                     /locus_tag="ON488_001742"
     tmRNA           complement(578..944)
                     /gene="ssrA"
                     /locus_tag="ON488_001742"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1115..1888)
                     /locus_tag="ON488_001743"
     CDS             complement(1115..1888)
                     /locus_tag="ON488_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3231937.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2032..2382
                     /locus_tag="ON488_001744"
     CDS             2032..2382
                     /locus_tag="ON488_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HCR3231938.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2363..3079
                     /locus_tag="ON488_001745"
     CDS             2363..3079
                     /locus_tag="ON488_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3231939.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFYDSGVA"
     gene            3079..4527
                     /locus_tag="ON488_001746"
     CDS             3079..4527
                     /locus_tag="ON488_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCR3231940.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4598..5107)
                     /locus_tag="ON488_001747"
     CDS             complement(4598..5107)
                     /locus_tag="ON488_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231941.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5097..5796)
                     /locus_tag="ON488_001748"
                     /pseudo
     CDS             complement(5097..5796)
                     /locus_tag="ON488_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6019..8139)
                     /locus_tag="ON488_001749"
     CDS             complement(6019..8139)
                     /locus_tag="ON488_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HCR3231942.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            8369..9547
                     /locus_tag="ON488_001750"
     CDS             8369..9547
                     /locus_tag="ON488_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HCR3231943.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9563..10321
                     /gene="aroD"
                     /locus_tag="ON488_001751"
     CDS             9563..10321
                     /gene="aroD"
                     /locus_tag="ON488_001751"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HCR3231944.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            10344..10829
                     /gene="ybaK"
                     /locus_tag="ON488_001752"
     CDS             10344..10829
                     /gene="ybaK"
                     /locus_tag="ON488_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HCR3231945.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(10900..12153)
                     /locus_tag="ON488_001753"
     CDS             complement(10900..12153)
                     /locus_tag="ON488_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCR3231946.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            12270..13619
                     /gene="gdhA"
                     /locus_tag="ON488_001754"
     CDS             12270..13619
                     /gene="gdhA"
                     /locus_tag="ON488_001754"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HCR3231947.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13731..15077
                     /locus_tag="ON488_001755"
     CDS             13731..15077
                     /locus_tag="ON488_001755"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HCR3231948.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
BASE COUNT         5044 a         2725 c         3107 g         4468 t
ORIGIN      
        1 tttataagta tggtgataaa atccgttccg ggctaccttt tttaggtagc ctactttaat
       61 ctttatacct ttctggatca acgaaagtat acttcaaata gtcataacgc cgatgatcgc
      121 tccgtgcgtc tggcacatca gtcacgatat caaacaaaaa atacacatct ttcttcattc
      181 tggtttttgt tgccggaatt ttaaagtagt tcttattaga gtaatagaga ttgattaata
      241 agctatcttc gattgctaaa aagaaaactt ctgaatccca caccttataa aaatctttga
      301 caaatctatt cgaaggatca aatttaaacc ataattgtgt ttttccttcc atcaacataa
      361 tgttcacctc aaaaagagta tacgaactaa tgttcttttt gtaaagtagg aatatcattg
      421 ataatatgga tggaacatat atattaaaaa gtgttctttt tgaatgctat tttgaatgcc
      481 attttcattc atttaacgaa aatctgcgaa aataaaaaat gctcaaaccc ttataaaata
      541 aggatttaag catctagcga aatctgctga aatctcacaa tggagacggc gggagtcgaa
      601 cccgcgtcca aacacatcgc cacttaaaaa tctacgttca tagtcaactc atttaaggat
      661 tcactttaca gcttgccgag tgacaggcat tctgtatcgc tagtctgatg ttctcttttt
      721 caacttacag acggaaagtt gaaacgtatc ccactaaagt taggaccctt actcgagcac
      781 atgggcgatg ccgagaggat ctacgctaac tgtttttagg cagctaaagc gtaagagttg
      841 ttttcgtttt tagcagttat atttaactgt aacgttttta cgtagacgta acctacgaaa
      901 cgcaattcaa gctcgactgt gcctgtcgaa tccgtaacgt ccccgttagc taacaagggt
      961 tacgtgtatt tttcatacaa aattagtata gcatatattg ggataaattc aataaaaaag
     1021 cgaatcatat cccattattt atataataac tgcccctttc ttaagaaaaa ataagcgatt
     1081 ttcttaagaa aagaggtagc ttcaaaaaaa gatcttaaat cagatcaaaa tacttcaatg
     1141 cgtggacaat tccgccttct gtatttttct ttgtgataaa ggtagaaagt tcttttaatc
     1201 cgtcataggc gttgcccata gcgattttgt tgtcgcaagc ttccaacaag gcaaaatcat
     1261 tcggaccatc gccaaatcca aaagtaggaa ctttttccag ctgaagttct ttttgcagac
     1321 gtttgacacc tgcccctttt gagattcctt tcttcactgt atcgatcgag taaggaccat
     1381 tccgataaaa agttagctca ggaaaatgtt cgtgatagta ttcgtcacct gattgagata
     1441 agatcagcaa catatttact gtgttttctt taaagcctaa aggatcaatt tccggaacat
     1501 ctgaatgaat gaagtcgtaa gcattgatca ttgtttggct atgaccggta caccagattt
     1561 tctgatcgtt atagtaagaa agttcatgac cgttcaactg tacatgatca tacatttttt
     1621 gacattcttc tgaagaaaat gtttgagaat agatttcttc gccgtctact cgaatgaaag
     1681 aaccattcat ggtgaccgca gaagtaatgc ccgcatcttc catgatagag tggatttctg
     1741 cttctgtacg tcctgtagcg atgacgggga gaacattgtt ttcttttaat gcgttcatag
     1801 cttttgccac ttcgggtgtg atttttgatt tcgcatctag taatgttcca tcaagatcaa
     1861 agaaagtgat tgcacgataa tttgacacaa ataaaactcc ttttttattg gaataagttt
     1921 atcttaacaa agaatgaaca aaagacaaac ctttcgtgaa gaattcctga acatattggt
     1981 tcagtcaaca atttagagta tactataaga agagaattta ggagggaaag aatgattttt
     2041 ttcagtattg gtatcttatt cttaataatt ggcagtcttt ttcggattct gccctcaaaa
     2101 ggaaatctgc ctttttatgg gtatcattcg cctcttgccg caaaaacaga cgctcattgg
     2161 cggctggctc aaaagacaag cggaaactgg ttttttctta tgggcttact gatggcattg
     2221 atcggctatt atttaaagac atctgggcat acgaattatt ttctgattga aatgcttctg
     2281 ctagtatttc caattatgcc tatttttatt atgacagaaa agaaattaca gaaatatgac
     2341 ctggaaactg gagggaacga taatgaatat tttaatgatt gaagataatc aatctgtttc
     2401 tgaaatgatg cagatgtttt tcttaaatga aggttgggaa gcaactttca agtatgatgg
     2461 aaaagaaggg ctcgatgcct ttttagaaaa cccacaacat tgggatatga ttacactaga
     2521 cctgaatttg cccacactgg acggtatgct agtaggaaga gagatccgca aagtttcaag
     2581 tactgtgccg attatcatgc tgacagctag agattctgaa agcgatcagg tgatcggctt
     2641 agagatgggg gcagatgatt atgtcacaaa acctttcagt cctctgacgc ttattgctcg
     2701 aatgaaagct ttgcatcgcc gtagtgagtt ggcagaagca agagaagaag cagtagtttc
     2761 agatgatcat tttgatatcg agactagtca tttcaagatg aatacgaaaa cacgagaagc
     2821 gtatctggac aaccggccaa ttgaaggact gacgcctaaa gagttcgatc tattgtttac
     2881 tttagcaaaa aaaccacgtc aagtattctc tcgggagcag ttgcttgaat tagtctggga
     2941 ttatcagtac tttggtgatg aacggacagt ggacgcccat atcaagaaat tacgacaaaa
     3001 aatcgaaaag gtcggaccac aagtcatcca aactgtttgg ggagtcggct acaaattcta
     3061 tgattctggt gttgcctaat gcgttatttg tatcagcaac tcttagcttt ctgcggaatg
     3121 gtcgcgttga tcttattgat cgttggagtt tcttttacac aactgacaaa acaaacgatt
     3181 gaagaaaaca attaccagca actgtttgga tatgctgaat cagttgaaaa gacaacgcaa
     3241 acctatgccg atacgctccc gcagtttagt caagatcagg cgtttcaaaa tgcattgctg
     3301 ctgacagagc aagtactgac agaacaaaat gtgaacttta tatttatcga taaaaacgaa
     3361 cgtgtcattt atccgactaa tacagcttta ctgaatttta ccttaacagc tgatcaatgg
     3421 aaaaatctga ggaatggacg tcaagaaaaa ttcacatcga ataaaaatat tttaggacaa
     3481 gcacaggcga cctcttacgc acttgtgcca tttaatttga atcatgaatt ctatggagca
     3541 cttgtagtta gtcaacctgc gcgaaatatc gataacagcg ttcgtccaat tacactgaac
     3601 ctgttcaaag gatttatttt ttccagtatc gttgcagtta ttgccagcta tgcttttgca
     3661 gcattccaag ttaagcgtat caatcggtta aggaatgcga cgaaagaagt gacgaatggt
     3721 aattttgatg tacagctccc cgtacatgac aaagatgaat ttgatgagtt agcagatgat
     3781 ttcaataaaa tgacgaattc attgaaagaa tctcaagcag aaattgaaga acaagaaaat
     3841 cgtcgaagac aatttatggc agatgcttct cacgagatga gaacacctct tacgacaatc
     3901 aacggacttc tggaagggtt agaatacaat gcaatccctg aaaatcagcg agaaaacgcg
     3961 attaaattga tgaaaaatga aacagagcgt ctgatccgtt tggtgaatga aaacttggat
     4021 tatgaaaaaa tccgtacgaa tcaaatcagt atggtcatta aaaaattcaa tggaacagaa
     4081 acattgaaaa atattgttgc acagttagaa gctaaagcag aagcagcagg agatacattg
     4141 acattgaaag ccgttgatga tattgatgtt tacgctgatt atgaccgatt tgtccaaatc
     4201 atggtcaata ttattcaaaa cgcgatacag tttactgaaa acggccaaat cacgattact
     4261 ttagaaaaag gctatcttga aacgatcatc acgattgaag atacgggaat tggaatgtct
     4321 gaacaacaaa tgaaaagtat ctgggatcgt tattataaag tagatccttc aagaaaaaat
     4381 acaaaatatg gtgaatcagg attaggttta ccaatcgtgc agcaacttgt acgcttgcat
     4441 aaaggaaaat tagaagtaga aagcgaacta ggaaaaggaa caaaattcgc tgttcgtttg
     4501 cctgacgtag aaatcaaaaa agagtaaaaa acaagcggta taaaagatca tgaatcgatc
     4561 ttctataccg cttgtttttt actataaaat gattgattta gcccgcgggc tctaaacgat
     4621 caatataagg actttgagca atagtagcat catgagtaaa gagtaagata ccttgatttt
     4681 cttcatgagc taaataagaa agcaagtgga gtagctcttg gatctccaat acactaagtt
     4741 catcaaatgt atcttcaata acaatattgt ttcgcttgga aagcaaggca tgaagtaatt
     4801 gcagctttac tttttcaaaa gacgtcaact cagctgccgc acaattaagc aaggaaggag
     4861 agatatcaag tttttcttga taggccaaac gatcttgttt gatttctttt tccggtacat
     4921 ccaacaggac atggtcttta agattcagat aaggaaacat cggccaattt ttttggatga
     4981 tcgcaaaatt atccagtttt gcaacaagaa cctctttttt caagtgctcc aatattttat
     5041 gctgtttttc gagaggacac aaaataacgg tcaagtgttc agcatgaatc aaatattcag
     5101 gtttcattac gtccaggcct cctactttgc aaatgatgga taaaaaaagt gaaagggaat
     5161 agactaagaa tgagacagca tccactgagc ccaataagag tttgggcaaa tcccttaagt
     5221 atatctgtga aaaaaagatc attttggaaa tcgatggtaa aaaaagtctg ttgatccatc
     5281 ggaattgtaa gtccgcttac cgaagtcaag atatcacgga tatctggcag ttcagtagtc
     5341 tttaagacaa gaaaattgat cctttgaaga agcgcttcat aaactgactg gaagcttacg
     5401 atccacaata aaaccaagat acaacaaaga aagagaggaa agaacagctg ccagaaaata
     5461 aaaaggaata atttggtttt agaaagacca gtcaggtgcc aattgatcaa ttcctgcttg
     5521 ttttgcctga ctgaatagta aaagaaaaag ataaaaagga aggcaaatag aaaaaataaa
     5581 ctgaatatgc cttttatata aaatcggcta gctaattcta aagccggaag aagctctgta
     5641 gatgcagaag cgccaataaa tgaaagccga ttgcaaatgg taaagagtca ggcatgctat
     5701 caataaaaaa gcagaaaagc ttgaaaataa acaatagagt attgtctgct ttttgtaata
     5761 aattaatcga gcagtagcat agcggattat tttcatactt ttcacctcta taaaaagtat
     5821 agaaaatgaa tatgaataaa gtatgaaatt cctttagtga aatcacgaat taaaaccaga
     5881 aaatattttg taaaaagcaa gaggttgtga agaagctgcc ctattctatt accgtagatg
     5941 caagcttttg aacactgttt attcgaaaag aggagcagcg acaataattt tgtcgctgct
     6001 ccttttaaat ttattttatc attcggaaga acttgtggtc gttccgtgaa gttcttggta
     6061 cgtttgcgtt ttataaagat caacagttga ttgtccgttg tgttcactaa agacactagt
     6121 tgacttgtca ccaagagatt tttcagcttc ttttaatttc tctaagccat tcttgtagtc
     6181 ataatcactg gtatcaattg ggtctaatcc actattcgta tagaaccgaa gaagatcacc
     6241 attattgatt tggtcagaaa cagctaactg tttatcaact ttttctttca gtgaatcaat
     6301 ttcattctgt acttcctcag taggttcagt aatagcttca ccagtttcgt tactatagat
     6361 cgtaccaccg tagtaagtat attttggtgt aacaaaatca ccatcacgga aagaaacaag
     6421 ctgttcatga tctttcgaga atagatcttg tcctaactga atataatttt ttgtatctac
     6481 acctagtaag tgaagtaatg taggcaaggc atcaacttgt ccgccgtaag tgtgattgat
     6541 tccgccctgt gtttgtccag ggatatggat catataaggg acacgctgca tttgtgcatt
     6601 gtcgtagttt gtccaagtag aacttgtttt tccaactaat tcagctagat ttttatttct
     6661 tgaattcgag acaccgtaat ggtcaccgta aaggacgatg actgaattat catacaagcc
     6721 gctttctttc aaataattga agaattcttg tacggcggta tctaaataat tggctgtcgc
     6781 aaagtaaccg ttgatcgttt catcatttgt attggctaac gggaatcctg cttcgtcatt
     6841 ggtgaatttt gaataaggat aatggttaga tacagcaatg aattttgaat aaaatggttg
     6901 ttgcagacgt tccaagtatt gtacggattg ttggaaaaat ggtttatcat gcaacccgta
     6961 ttggaacgaa ttgtcatcat taacatcata ataagaagaa tcaaagaaat aatcatatcc
     7021 taaattcttg tatgtctcgt ttcgattcca gaatgtacca gcgttcccat ggaataccgc
     7081 actagtgtaa ccttgtgttt gacttaaaat atcaggtgca gcttggaaag tattttttcc
     7141 gcctaattgt gtgaacaagg agccttgatt caagccaaac aatgaatttt ccatcagcgt
     7201 ttccgcatcg cttgtttttc ctgcttttac ttgatggaaa aagttgtcaa aactgaacgt
     7261 gctgttgctg tggtaaagac tattgatgaa aggtgtaact tcatgctgga gaccattctc
     7321 atctgtcaat ttataatcga tcaggaattg ctggaagctt tctaaatgga tataaatcac
     7381 attttttcct ctagcgagcc cgaacaaatc gtcatttggt gctgcataat gttcttttac
     7441 ataattttct acttctttca tatcattggg acttgcttct gcccgcactt ggtttgtctg
     7501 gtaagtttga acaccgtcat aaaccatgaa agcattcaag ccaagatatt tgaccaaata
     7561 atcacgagag aatgttcgag tcagcaattc tggacgatca gcttccgcca taaaaagatt
     7621 tcctgagaaa atcataactg ctaatgtaga gatcgcaaaa gccattcttg ctcggatcgg
     7681 gcgagggtcc aacttgattt tttttgcaat cagcagaaca gtcaagataa taaaatcgat
     7741 ccaatagatc acatcatatg ggcgaaacag tcgaatggca ctttctccca gaccactcgc
     7801 tactttccca gcacctaaaa tcgtgttgat cgtaatgaag tccgtgaatt ctcgataata
     7861 agtgacattc gaaaaaacaa gcaatgtcaa aagaaaataa atgaccatca tcgtgatata
     7921 agcaactcta gggcgtctga tataaagagc aattccaagt aataacaatg tagttgcaat
     7981 agggttgata aacaagataa agtattgaat gccactttcg attccgagat ggaaatcaac
     8041 taaataggca aaaatcgttt tcaaccaaag taaaacgact agtaaagaaa aaaatccgag
     8101 cctcttattc aaaaaggcag gtgtttttat acatttcaag ataatcttcc tttctgcact
     8161 tcttaatcac agaagtgtcc tgaaaccatg ttacacagct cacttattct catttatttt
     8221 actagtatga caatatagtg tcaattgaaa ccagaagttt atgctgtttc attaaggttt
     8281 tctttaagct tcatgaaaaa atgagcagta agacaagtcc tatgtttttt gttatacttg
     8341 ggaagagaaa gctaaagcag gtgaaggaat gaaagtaaaa gtaaaaaaaa gagcaagcaa
     8401 tcgattgaaa aaaggatatc cactgatcca aaaagaagac cttgctcatc cccaaaaaga
     8461 aaccacgcaa tgggtggaat tagttgattc gcaaaaccaa tttatcgcaa aaggatatct
     8521 aggaaagcag aataagggaa tcggttgggt attgagccag cagaacatcc catttgatca
     8581 atcttttttt gaagaatttt ttgtgaagtc aaaagaaaaa agaactttct ttttttcaga
     8641 tgattctact accgcttttc gtatattcaa tggagaagga gacgggatcg gcggtctgat
     8701 tgttgattat tatgcaggtt atgctgtttt ttcttggtat aacgaaacgt tatatgcaca
     8761 tcgtgaatta ttgattcaag cttttcgtga aatctacccg gaaatcatag gaggctatga
     8821 gaaaattcga tttgaatcag taaatctgcc tgagagccag ttcatttacg gaaaagaggc
     8881 accggaaccc ttgatcgtaa aagaaaacgg agtaaaattt gccgtttatt taaatgaagg
     8941 attaatgact gggatctttt tagaccaaaa agaagtacgg ggatcattag cagaaggttt
     9001 cgcttctggg aaaacagttt tgaacatgtt tagttatacc ggcgcctttt ctgttgctgc
     9061 cgcaatggga ggggcaatcg aaacaacaag tgtcgatcta gcaaaacgca gtttaaaaaa
     9121 aacacaggaa cagtttgaag tgaatggttt ggatgtcgat cagcaaaaaa tcattgttat
     9181 ggacgtattc gagtatttca aatacgccaa aagaaaacaa tttttatatg acatgattgt
     9241 attggatcca ccaagttttg ccagaaataa gaaaaaagtc tttcgcgtag caaaagatta
     9301 tggggaactg gtcaaggata gtctggatat tttagcagaa gacgggatac ttattgcgtc
     9361 tacaaatgct gcgaatgtct cgatagaaca attccaaaca atgattgaag aggaattcca
     9421 tgccaaaaat gtttcttttg aacaacttgc tttatatcgt ctgccaaaag atttccagac
     9481 gacggatacc tttttagaag gcaattatct gaaagtgttt gtttatcaaa ttaaaaataa
     9541 ccattagaag gagcgatgca gaatggttcg ggtaaaggga ttgaatatag gaagcggtag
     9601 accaaagatt tgtgcgcctc ttatcggggc cgtccgagag gaagtattac gtgaagcagt
     9661 tcttgcacgt gaagcagggg ccgatttagt cgaatggcga gtcgatcatt atcgtgaagt
     9721 tttttctttt gatgaagtag cagaaacatt ggttcttatc catgagatgc ttgatggact
     9781 gccgttatta tttacgtttc gtaccttagc tgaaggcgga gaacaagaca tatcgatccg
     9841 tcagtatcgc gacctttatg aacatgtgat acacacagga ttagtagata tggtcgatat
     9901 cgagttgttc aaagtagaaa gtctaggaaa aagactgata gaggaaatca agtctttaaa
     9961 cattccttta attatcagta gtcatgattt taaagaaaca ccagcagacc ctgtcttgct
    10021 ttaccgattg aatgttatgg aacattttgg agccgatatc ggaaaactgg cagtaactcc
    10081 caataatgaa cgagatgttt tgcggttgat ggagttgact agacgggcaa atgcttttgt
    10141 ctccatgcct attattacga tgtccatggg aaatcttggt aaaatttctc gtctggttgg
    10201 cggaacgacg ggttccgtta tgacatttgg ttccttaagc agcgattcta cttctgctcc
    10261 aggacaatta ccggtcaaag cattgaagca aattattcaa ttattaaatg aaccgttgta
    10321 gaacaagttt gaggtgatat tttttggcaa agaaaaaaat agtaaaaacg aatgcaatcc
    10381 gtatggtcga acaaaaaaag attccctata cagagcacga atatgagtgg gacgaaagcc
    10441 acctaagtgc gtcatcggtc gctgaacagc ttccagaaag ccaatctcgt atatttaaaa
    10501 cactggttgc tgtgggcaat gtgacggggc ctcttgttgc tgtgataccg ggagaagccg
    10561 aattgaatct aaaaaaatta gcaaaagttt cagggaataa aaaagtagaa atgctccatt
    10621 taaaagattt ggaagcaacg accggataca tacgtggtgg ctgctcgcct ataggtatga
    10681 aaaaactatt tcctacttat ttagatcaaa ttgcagaaag ctatgaacaa atcattgtct
    10741 cggctggcag aagagggcta cagatggagt tagcacctca agatatctgt gcattaacga
    10801 gcggacaatt tgcagatata aaacaataaa tcatacgtat aaaagaaaga aggaggccgg
    10861 gatgttgttt gtccagtctc cttctttctt ttttatacat tatgctcttt gcccggcatt
    10921 cattcctgct acatgccctg tagcgaaagc cgctgtgata ttaaagccgc cagtataacc
    10981 attgacatcc agtaattctc ccgcaaaata cagaccatca atgattttac tctccaatgt
    11041 tttaggataa atttccttta gagaaacccc tccgccagtt acaaatgatt tctcaatagg
    11101 aaaagttttg ttgattgata gcttaaactc tttgcatagt tgaacaaaat cttgaatttg
    11161 tttttgagag gcttgttgtc ctgtcagatg atccatttca agccgctcaa gaaagaaaac
    11221 taacaatcgc tcaggcaata taccatgcca agcattgacc aagttctttt tggttgcttt
    11281 acttttttct gtcaatatat gaataagctc ttgtttggtt tgtgtaggga aacaatccag
    11341 agaaagtgtc actggttctc ccgttttctc taattcttta ttgacaaaac ttgaacaacg
    11401 cagtgcagcc ggaccagaaa taccgaaatg ggtgaaaagt aaatccatcg tatgttcagt
    11461 caatacacga ccttttttat ttaaaacgcg taaagtgatg tcttgtaaag aaagcccttg
    11521 aagtgttttc tcctgaatat acggttcatc cgatatcaag ggggactctg tcgcataaag
    11581 aggcgtcacc gtgtgaccca ctcgcttcac gatcttgtac ccatctccag tagaaccagt
    11641 agatggataa gtccgtccac cagttgttaa gataatggca ggagcatgga actcttcgaa
    11701 ttccgtgcgt ataccgtaaa ttttatgttc tttgtggatc aatttctcta ctcgagtaga
    11761 gaatagaagc gtcacatcta gttctttcag acgattgagc aatgcttcga taatcgtttt
    11821 tgatttattt gttacaggaa acatccgtcc atgatcctct tcttttaaat gtacgccttg
    11881 tgattcaaag aagttcatga tatcgaaatt attccattgc gcaaacgtac tatataaaaa
    11941 ctttccattt ccaggaatat gtgcaatcaa atcatcaaca ggacgattgt tcgtaacatt
    12001 gcaccgacca ccacctgtca tcagtagttt ttttcctgct tttttgtttt tttcgatcaa
    12061 gagtacgcgt gcgccttgtt cagctgcact gatcgctgcc atcatcccgc ttgttccagc
    12121 gccgactacg atcacatcat acagtttttc cattccctca cctcaaggaa agtgtagcat
    12181 atctgaagaa agaaaacaga aaaaaatgtt ttgagccaaa agagaaaatg agctaaaatg
    12241 agggaagata agcaaaggag cgtggaacga tgacaaacgc aacagaatat gttcaagcaa
    12301 ttcaagaaaa gctacatcaa aaggatcaag ggcaagaaga atttttacaa gcaatcgatg
    12361 aattcatgcc cacggttatg tcttttttgg acactcatcc cgaatatatc gaaaagaata
    12421 tcttagaact tttaacggaa ccagaaagag ttattcaatt tcgagtgcct tggcaagatg
    12481 atgaaggaaa ctggcgagta aatagagggt accgtatcca atacaactca gctatcggcc
    12541 cttataaagg tggattgcgc ttccatccta gtgtcaatct aagtatcttg aaatttttgg
    12601 cttttgaaca gattttcaag aatagtttaa ccggtctgcc aatcggtgga ggaaaaggcg
    12661 gaagtgactt cgatcctaaa ggaaaatctg ataatgagat catgcgtttt tgtcaaagtt
    12721 tcatgctgga attgtcaaaa catatcggcc catcgattga tgttcctgcg ggagatatcg
    12781 gtgtaggagc tagagaaatc ggctatttgt tcggcgaata taaacgattg aaaaaatatg
    12841 atactggtgt gttgacaggt aaacctttgg atttttgggg aagtaagata cgtacggaag
    12901 ctactggtta tggattagtg tattatgtca aacatctatt gaacgaagaa aaagattcat
    12961 ttaatcaaaa aacagttttt gtttccggaa gcgggaatgt agccatttat gcaatcgaaa
    13021 aagtgcaaga gctaggcggg aaagttgtta catgttcaga ttctagcggg tacatctatg
    13081 atccagaagg aatagatgtg aaactattga aagaagtcaa agaaatcaat agacaacgtt
    13141 tgacggaata cgcaaaccaa cgtccttctg ctatttatca tgctggagaa tctgtttgga
    13201 cattgaaaga aaaagcggat atcgctttgc catgtgctac tcaaaatgaa atagacgaaa
    13261 gcttggccga aatcttagta gaaaatggga tcaaaatcgt agcagaaggc gctaatatgc
    13321 catgtacagt aaaagctgtt tctgttcttc atgaagcagg cgtgtggtat tgtccaggaa
    13381 aagctgctaa tgctggagga gtagcagtat ctgctttaga aatgagtcag aacgtccagc
    13441 gattgacttg ggaaagagag caagtggatg agcagctgga tcaaatcatg gaaacgattt
    13501 accatacgtg tcgccaaaca gcagccgagt acggcgacga aaaaaatctg cttcttggag
    13561 caaatgttgc tggatttgaa aaagttgcca aagcaatggc agcagaaggt ttagtttgaa
    13621 aaatgaaact ttcttggaaa tattgtcagc attttgttta tttgcttgaa aaataataaa
    13681 aaaaaacgta aagtattacc tgtagagtaa acctataagg aggagaacaa atggcacaca
    13741 ttcattttga ctattcaaaa gtagcaccgt ttgtcaacga acaagagtta gggtacatgc
    13801 aaagccaagt aacagcagcc cacaacgaat tacgggaagg tactggcgca ggaagcgact
    13861 tccgcggctg gatcgattta ccaacgaact atgacaaaga agaatttgca cgtatcaaag
    13921 aagcagctaa aaaaatccaa tctgattctg aagtattagt tgttatcggt atcggtggtt
    13981 cttatttagg cgctcgtgca gcgatcgact tcttgaatca cacattcttc aatttattag
    14041 atagcaacac aagaaaagca ccacaaatct tctttgccgg aaattcaatc agctcaacat
    14101 atattgctga cttgatcgaa gtaatcggtg atcgcgactt ttcagtaaac gttatttcaa
    14161 aatctggaac aactactgaa ccagcgattg cgttccgtgt attcaaagag cttcttgtta
    14221 agaaatatgg acaagaagaa gcaaacaaac gtatctacgc tacaacagat aaagcaaaag
    14281 gtgcagttaa agtagaagca gatgcagaag gttgggaaac tttcgtgatt cctgatgaca
    14341 tcggcggacg tttctctgta ttaactgctg ttggtttgtt accaatcgct gttagtggtg
    14401 cagatatcga tgcattgatg caaggtgccg ctgatgcaag caaagcatac tcaagcgaca
    14461 aactagaaga aaacgaagct taccaatacg cagcaatgcg caacattctt taccgtaaag
    14521 gcaaagtaac tgagttgttg atcaactatg aaccaggaat gcaatacttc tcagaatggt
    14581 ggaaacaatt gtatggtgaa tctgaaggaa aagaccaaaa aggcatctat ccttcaagcg
    14641 caaacttctc aactgatttg cactctttag gacaattcat ccaagaagga cgtcgcaata
    14701 tttttgaaac agttgtgaag gttgaaaaac ctcgtaaatc aatcacaatt cctgaacaag
    14761 cagaagattt agacggtcta ggctacttgc aaggaaaaga agtggacttc gtaaatacaa
    14821 aagcatttga aggaacattg cttgctcata cagacggtga cgtgcctaac ttgctagtca
    14881 aaattccaga aatggatgct tatacattgg gttatacaat gtacttcttt gaaattgctg
    14941 taggtatttc aggttacttg aatggaatca acccattcga ccaaccaggt gtagaagctt
    15001 acaagaaaaa catgttcgca cttctaggca aaccaggctt tgaagatctt gctaaagaat
    15061 tgaacgaacg cctgtaagat aagggttttt cgctagattt aaataatcag tgatagaaac
    15121 atgttcgctt taaaatgaaa actggtaccc atttaggtac tcaaacatac tgcatcgttt
    15181 attcagaata aggggctgtg acaagacgtt tgtcacagtc ccttgtttgt atagaaatcg
    15241 attgattgcc ttgctcttta gtttgtttta ggactttaag aacagtgagg ctgacttcga
    15301 aggttaattc tgtttttttg ttttctagaa tcagtaagca aaaa
//
LOCUS       DAJSMK010000054        15242 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.056, whole genome shotgun sequence.
ACCESSION   DAJSMK010000054 DAJSMK010000000
VERSION     DAJSMK010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.056"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(21..251)
                     /locus_tag="ON488_001756"
     CDS             complement(21..251)
                     /locus_tag="ON488_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231949.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="ON488_001757"
     CDS             complement(687..1253)
                     /locus_tag="ON488_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCR3231950.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="ON488_001758"
     CDS             complement(1253..2209)
                     /locus_tag="ON488_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HCR3231951.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="ON488_001759"
     CDS             complement(2209..2865)
                     /locus_tag="ON488_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HCR3231952.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="ON488_001760"
     CDS             3235..5253
                     /locus_tag="ON488_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCR3231953.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="ON488_001761"
     CDS             5680..8094
                     /locus_tag="ON488_001761"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HCR3231954.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="ON488_001762"
     CDS             8442..9995
                     /locus_tag="ON488_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCR3231955.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="ON488_001763"
     CDS             complement(10376..12160)
                     /locus_tag="ON488_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231956.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="ON488_001764"
     CDS             complement(12175..13896)
                     /locus_tag="ON488_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3231957.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="ON488_001765"
     CDS             13996..14757
                     /locus_tag="ON488_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCR3231958.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4957 a         2792 c         2996 g         4497 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 tt
//
LOCUS       DAJSMK010000055        15096 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.057, whole genome shotgun sequence.
ACCESSION   DAJSMK010000055 DAJSMK010000000
VERSION     DAJSMK010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.057"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="ON488_001766"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="ON488_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HCR3231959.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="ON488_001767"
     CDS             complement(322..891)
                     /locus_tag="ON488_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HCR3231960.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="ON488_001768"
     CDS             1077..1979
                     /locus_tag="ON488_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR3231961.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="ON488_001769"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="ON488_001769"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HCR3231962.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="ON488_001770"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="ON488_001770"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HCR3231963.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="ON488_001771"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="ON488_001771"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HCR3231964.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="ON488_001772"
     CDS             8547..8732
                     /locus_tag="ON488_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HCR3231965.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="ON488_001773"
     CDS             complement(8794..9990)
                     /locus_tag="ON488_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HCR3231966.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="ON488_001774"
     CDS             complement(10160..11596)
                     /locus_tag="ON488_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HCR3231967.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="ON488_001775"
     CDS             11889..12698
                     /locus_tag="ON488_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3231968.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12884..15037)
                     /locus_tag="ON488_001776"
     CDS             complement(12884..15037)
                     /locus_tag="ON488_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HCR3231969.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT         4408 a         3201 c         2665 g         4822 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agctgctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccacaaaa
    12721 aagaggttgt gacaattttt gtcacaacct tttttgccga gtaaacggtg ttcaaaagcc
    12781 agtttctcgg tatgaagtca aatttaagca aaaatgtgag aagctatttt cacaaaattt
    12841 ttcttcatac tcgaaactaa gcggcttttt cacgacctct tttttatttt gccatgaaca
    12901 tatcataata cgcgtccatt atttctttag caatcgtcaa gtttatgtgg tcttgttcgt
    12961 ctaataagtt cggcaagaca acactgatgg caatttccgg attgtctgtt ggtccgtatg
    13021 ccacgatatt actattgact gtcgcaatat ctggatgacc ttccgcaacc gtttctgcag
    13081 tccctgtttt tgcggaaagg tccattttcg cactggctaa tggtttggct gttgtgtaag
    13141 gatcggtacc atggacaact tggtggaatc cttcacggag gatcgccata ttttctgcag
    13201 aaatattgac cgtattttct actgttgtgc caatttcttt cttcacttca cccaagtttc
    13261 cattttcgtc attgccatag atcgctttga ctaggtgcgg ctgtactcgt ttcccgccat
    13321 tagcgactgt tgaagcatat tgagctaatt ggattggtgt atatgtgtca aactgtccaa
    13381 atgccaaatc ggtaaagtta cctggagcat accattcttt gccattatcc gcattgaact
    13441 tcttcatata atcaacagaa cgtgagatcc caggagattc attcggcaaa tcgatcccag
    13501 tcgttgtacc aagaccaaac tctttgaaag agtctctcaa ttgctgataa gctttagctt
    13561 cttcatctaa actaggtagt cccattccag gtgtatagtc tagtcctaac atctttaacg
    13621 ccactttgat catatacgta ttagaagaca attccgatgc tttgactgca tcaagagcaa
    13681 cttgtccgct tcgattaaag acagagcttt tttctgaagc accttgcaga cgaatcggct
    13741 catcaatcaa aacttgattt ccgctgatcg cgttacttgc ccagcctgct gtcaaagtac
    13801 cagccttgac tacagaccct ggatcaaagg cgctagtaat cgtgcctaaa gcattctcgg
    13861 tgatttcttt ggaaccttgt tcatgactga aaccagtcat tgctagcact tctcctgtct
    13921 gaggattcat agccactgca taagcaccag gcgaatactg tgctttgccg ttgttgatca
    13981 atgtttgata attccttttc aaaatttctt ctacttttga ttggaattct gcattcatag
    14041 ataacattaa attagaacct ttttccccag agaagatttc tttttgattc gaaacatttc
    14101 cttcattatc aagggaaact tcatattggg ttttggttcc ttgcaggaca tcttcatatt
    14161 gtttttccaa ataactttgt cctacacggt cattccgaga ataacctttt gctaggtatt
    14221 tctctgcttc atctgctgga agtccttgct tttcagtcgt cacactgcca agaatacttt
    14281 tcagtgaact tgctgcatta tattctcgtg tccagtctgt gccagtcgaa actcctggaa
    14341 gttcagaagc gcgttctgcc acaacagcta actcttgatc agtaacacca gagtttttga
    14401 tatagacagt gtttaattca tatgcactat tcatccgttt aaagatggta gcaattttta
    14461 attgctcctc gtttaaatta atctcatcag ctgtgacttt attgaccatc gcactatatt
    14521 gttcgctgtt ccctaattgc ttttcttttg ccgaaagtct ttttgtggct tctttcaaat
    14581 gtttgggatc agccagccaa aaatcttttt tatctctatc tgtcagattt tcatctaccg
    14641 gaacatcgat cagcgagttc agcttcgttg cgatttcaag caaatcttta gccgtaactt
    14701 gtgttcctct cgtatatgtg atggcctgat tcgctttatt cgtaactaaa gcttttcctg
    14761 tggagtcgta gatcattccg cgaggagtac tttcttggac cgtaatcgta gaagtagact
    14821 tcactcgcgc ctccatctct tcgccgttca cgatctgcaa ataacccaat ctagcaatca
    14881 acgcaacaaa taacgtaaat ataatgaaaa aaagaaaatt taagcgaaaa ggaacatggg
    14941 accggcgaaa cgttttgttc ttaggttctt gtgcaccttt tcttattttt tctaaccaag
    15001 aagtatttaa tatttttttc ataaaatctt tcatcatttc ctatccttcc gcctatttac
    15061 attcatgctt cattgtaccc aaaaacttct taataa
//
LOCUS       DAJSMK010000056        15036 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.058, whole genome shotgun sequence.
ACCESSION   DAJSMK010000056 DAJSMK010000000
VERSION     DAJSMK010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15036
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.058"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            1..510
                     /locus_tag="ON488_001777"
     CDS             1..510
                     /locus_tag="ON488_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3231970.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            603..1765
                     /locus_tag="ON488_001778"
     CDS             join(603..879,879..1765)
                     /locus_tag="ON488_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCR3231971.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLTPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2045..3025
                     /locus_tag="ON488_001779"
     CDS             2045..3025
                     /locus_tag="ON488_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3231972.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3147..4565
                     /locus_tag="ON488_001780"
     CDS             3147..4565
                     /locus_tag="ON488_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HCR3231973.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4636..6105
                     /locus_tag="ON488_001781"
     CDS             4636..6105
                     /locus_tag="ON488_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3231974.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6115..6582
                     /locus_tag="ON488_001782"
     CDS             6115..6582
                     /locus_tag="ON488_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3231975.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6618..7490
                     /locus_tag="ON488_001783"
     CDS             6618..7490
                     /locus_tag="ON488_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCR3231976.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7572..10106
                     /locus_tag="ON488_001784"
     CDS             7572..10106
                     /locus_tag="ON488_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCR3231977.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10262..11035
                     /locus_tag="ON488_001785"
     CDS             10262..11035
                     /locus_tag="ON488_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3231978.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11028..11819
                     /locus_tag="ON488_001786"
     CDS             11028..11819
                     /locus_tag="ON488_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCR3231979.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            11829..12320
                     /locus_tag="ON488_001787"
     CDS             11829..12320
                     /locus_tag="ON488_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3231980.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12338..12748
                     /locus_tag="ON488_001788"
     CDS             12338..12748
                     /locus_tag="ON488_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR3231981.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            12752..14152
                     /locus_tag="ON488_001789"
     CDS             12752..14152
                     /locus_tag="ON488_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HCR3231982.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14175..14549
                     /locus_tag="ON488_001790"
     CDS             14175..14549
                     /locus_tag="ON488_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3231983.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5227 a         2123 c         3022 g         4664 t
ORIGIN      
        1 ttggtacaag gaatagaaag aggtgtttat gtggttgata aaattcagtt taatcaagtt
       61 atagaagaat tcatcaaagt aaataattta atgacccata ttcaaaaacg accaatcaga
      121 ataactaatg atctaaaact cagtacgagt atgattcatt tgattgatgt gattggaaat
      181 tatcctgaaa ctagtattac ggaattagct gatcgattag gcgttaccaa aggagctgta
      241 tcccaacaga ttcccacttt agagaaaatg aatcttataa gcatttctca aaaaaaagga
      301 aataagaaaa ctaaacttgt atcgttaaca aaatatggtc gaaaggtgta cgaatcacat
      361 aattatttac atgaagagct ttatagctca ataaatgaag cgttagaatc attctcacca
      421 gaccaaattt caaccattaa acagattcta gaaaaagtat cttatacaat caatgaatat
      481 caagtaagtc tgacaagaaa ggaagattga catgaaaaaa atgatttttg aatcggctac
      541 actagactag acagaaaaaa taaggtgtgt aaaataaatg aaaacacact ggaggaattt
      601 ttatgtcaag acgtcaacgt agaacctatt caaaagaatt caaacaacaa gtcgtcgatc
      661 tttatctcgc aggaaagccc cgagctgaaa tcattcgaga ttatgagctg actacctcgg
      721 cctttgataa gtgggtcaag caagcgcaaa ctactggctc gtttcaggaa aaagataact
      781 tgacccctga acaagtagaa ctaattgcat tacgaaagaa aaataaacag cttgaaatgg
      841 agaatgacat tttaaagcaa gcggcgctga tattgggacg aaaagacaag taattgatac
      901 caataagcac aaatactcaa tatcagcgat gtgtaaagtg ttaaacatct cttgccaaac
      961 ctattattat caagccaaac cagttgaaga tgaatcagaa ctggaagaac tcgttcaaga
     1021 agaatttatt cgcaatcgaa aagcttatgg taccaggaag ctgaagcagt gcttggccaa
     1081 tctaggtctt caagtgagtc aacgcagaat cggccgtatg atgaaacagc gtggcttgcg
     1141 ttcaacatac acattggctc atttcaaatt ccattcttct acttgtaacg aagccaagac
     1201 cgccaatatt ctagacggaa ccttcctaca ggaaaagtca ttagaagcga ttgtaaccga
     1261 ccttacctat gttcgtgttg ggaagaaatg gcagtatatc tgcctgattc ttgatttgtt
     1321 taatcgagaa atcatcggct attcatgcgg ggagaagaaa gatgcgacgt tagtcaagga
     1381 agcttttgca aagattccgt actcgttgaa taatgtacaa ctttttcaca cggatcgtgg
     1441 aaaagaattc gataaccaga cgattgacga aattttatgg gcctttaata tcacgcgttc
     1501 cttaagcaaa aaaggctgcc cctatgataa cgccgttgca gaatccacct ataaatctgt
     1561 caaagtagaa ttcgttcatc aataccgctt tgagacattg gctaatttgc gattagagct
     1621 atttgattac gtccattggt ggaataccat ccggctgcac ggcacgttag gctatgagac
     1681 accgatcagt tttcgacagc agagattggc gcagcgaatc cttgataatg agctcggatg
     1741 tgataccggt ggcgaggcac cttaattatt tgaatgagct tctgccttag agaatcagat
     1801 tcgaggaggc tcgttgtcaa gggcagtcgg aacaccagca gcaagcttac gcaatacctt
     1861 ataatttttg tcaaaaaaag tgttgccatt ccacatatat ctttaaacag ctattgccag
     1921 ataaaaataa atgatattat atatataaat acttatccga aaaggggaat gagagagtca
     1981 aggttcttgg aatgtcgaat agtcgagtag gtagattttc tatctacaac cttgttgttt
     2041 aaaaatgaaa aaaattggaa ttagagaagt tgcgaaagag gcaaatgttt ctcctacgac
     2101 tgtgtcgagg gtattgaatg atcgtggata tttgagtgag gaaacaaaaa gaaaagtttt
     2161 tgatgccatg aaaaaattag aatactatcc taatgaactg gcgagagcac tttttaaaaa
     2221 cgaaacatat accgtaggtt tgatttttcc tacaattact aatccatttc acgctgagtt
     2281 aattcaagat atcgagttcg agctttccag caggggatat aaagtgttgc tgtgcaatag
     2341 cttaaacaat ccaacaaaag aaaaagagta cttgacgatg ttgagaaaga atcaggttga
     2401 tggaattata gtaggaacgc acaataaaga tattgcggat tatgatattc cagggctacc
     2461 tattgtagcg attgatagaa gtcttggtga aaatacagtt acagtatctt gtgataatta
     2521 caggggtggg gaattagcta ctcaactact tgtaaatcat ggctgtcaga atatactgtg
     2581 tattcgggga gatagtaaga taaagctacc cgcgaatagt aggactttag catataaaga
     2641 tgttttgaat aaattcatgc tggaaccgtt agtcctagaa gtaccatttg taaaagaaat
     2701 caatgaaaaa aatgaaataa ttaagacata tctggaaact catccaaata ttgacggggt
     2761 ttttgcagga gatgatttat tggcttcttt ggcgattaac aacttaggaa gttcgggcaa
     2821 aagagttcca aaagaggtta aagtgattgg atttgatgga gctcaacaaa cattgattta
     2881 taatccagaa ttatcaacta ttcaacagcc tatagatcaa atatctaaag tagcagtaaa
     2941 aaaattattg aatatgatta agggcgaaaa ggagacggat gaactttcac ttccagtaaa
     3001 gctcataaaa aaaaatacag cataagttaa atcggcgaaa aattccttcg tcgatttaaa
     3061 aatattttta tgaaacgggt tgacatatga aacgggttga catatattag ttgtgaagat
     3121 aaaaaccttt tcactggagg aagaaaatgg agaaattatt aattaaaagc aataatcatc
     3181 aactttacta ccaacctaag gatgtttggg tcggagatgt tatgccttac gggaaagaag
     3241 gaaaattctt tatttatcat caacgtgata ctagaaatcc agttcctttt ggagaaccgt
     3301 ttggctgggc tttagcaact acgaaagatt ttgttcattt tgaagacttt ggggaatctc
     3361 ttttaagagg ggatgacaat gagagagacc agtttatcta cgctggttct gtatttgagg
     3421 caaatggaaa ggttcacgca ttttatacag ggtataatcg tgaattctta gcgcagggaa
     3481 agacatctca agtgttgctt catgctgaga gtgatgattt tgttcattgg gaaaaatcag
     3541 aaacagcatt ggagttagaa ccacaagaag ggtatgatat tcgaaactgg agagatccat
     3601 ttgtcgtttg ggatgatgaa aaagaagaat atttgctaat tttaggggcg cgaaagggtc
     3661 aggataaaca tctacaaacc ggacgtttag tggaatttac atcaaaagat ttaactaatt
     3721 gggaattcaa aggtgatttt tgggctccgg gattgtatac catgtttgaa atgccagaac
     3781 ttttcaagat tggtgactgg tggtatcttg tctattcaga atactcagat ggaaataaaa
     3841 tactctatcg aatgagtcaa agtttggaag gtccttggat taagcctaaa gatgaagctt
     3901 ttgatggacg ggcttattat gcaggtagaa cagcttatga tggaaaacgt cgagtcctat
     3961 ttggatgggt accaacaaaa gatcaagaaa atgataaaaa caattattta tggggaggta
     4021 ctttggttcc tcatgaagtc tatcaaaaag aggatttttc acttggggta aaacccatag
     4081 acgaagtgtg gaatgcattc ataaatttac atgatattgc cgatgtagag atagaaacag
     4141 cagacacaag agaagaagta acgcttgtca aaaatagtgg aactttgttt aatttagaaa
     4201 caacaatttc atttgatgag aatcttagtg acttttcact gagattatat aaaaaccttg
     4261 agacagatga atcttacgaa tatcgcttca atttagatga ggggcgtctt acatttgata
     4321 aaaacccttg ttacccttgg tttcaatata tggataaagg acttattaga cctatatctt
     4381 taaagcctaa ccaatcttat aaactaaaag tgattgttga tgacaatata atgacacttt
     4441 atattgatgg aatcgctctt aacgctcgtg tacatggttg ttttggtcaa gcaattacta
     4501 ttacagcaac aaatggatca atgactgcaa taaataccaa gttttcaaat gaaataaaga
     4561 aataataaac gtcaatcatg tggcaggtct gaaaatcaaa catgacctgt cacatttaaa
     4621 agggaggata aatgaatgga ctacaaaaaa attgccgaag atgtattgga aaacgttgga
     4681 ggaaaagaga atatctcaag cgctacacac tgcattactc gtttacgttt aattcttaaa
     4741 gacaaaagca aagcgaatat ggaaatgctt gaggaaatag aaggtgcaaa aggtgttctt
     4801 ttcaatagtg gacagttaca agtaattttc ggaacaggta taattgaaaa ggtttacaaa
     4861 gagttcgttg aattgacagg agctaaggaa gtatccgttt ctgaaatgaa agacgaagga
     4921 gtcaataatt caggaaatag acttcaacga gcttttaaag ttttctcgga tatctttatt
     4981 ccgatcattc cagcttttat tggggcagca atggttttag gaattcgttc gttgattacc
     5041 actcctggaa tgtttggaat ggatggctca ttcgctgatc acaatgtatt cctaaatgat
     5101 ttatccaaat ttctgggtat tattgcaacc acatttgatt atttaccagt tttagttatg
     5161 tattctgcaa caaaacgttt tggcggaaac cctattttag gattacttgt aggatttgtt
     5221 atgattcatc caggactagc caatcggaat gatttcgtca tgggaactat aaagcctgat
     5281 tattggcatt tatttggatt aagcattcca gcagttgcgt ttcaaggggg tgtttttcca
     5341 gcaattttga cttcttggtt tttagcaaaa gttgagaaaa ttacaaataa atattctcct
     5401 caagtacttg cttacatttt agtcccaact gtgacaattg ttcttgccaa ctttgcacta
     5461 tttttagtgt ttggtccatt ggggaatttt atcggtaatg ttttaggtgg aatcattgat
     5521 ttcctatata tgaagatggg tgcctttggt gcttttgttt ttgcaggcgc gttacaacca
     5581 ttagttgtaa caggaacaca acatgctatt caaggtattg aggcaaactt agtcgcaaca
     5641 actggattca attatatcca acctatttgg tcagtttcaa ttattgccca aggtggcggt
     5701 tgtattggta tgtatttact ctttaagaaa aaatctaaag atagagatat tgcgatttca
     5761 agctttattc caacactggt aggtattact gaaccggcta tctttgctgt taatttgaaa
     5821 tattcaatcg ttccttttgt ttgctcgttt attggtgctg gttttggtgg agcatttatg
     5881 aaaatttttg atgtaaaagc cattggacaa ggattgactg tattgccagg tctgactatt
     5941 gctaatccag ttcttcctta tatatttggt aatctcatag cattcatttt accaatcatt
     6001 tttattctcg cttatgataa atataaagtg tttatccctg aagctaaaca ccgtaaattt
     6061 gcagaaaaaa ctgactcaaa aaaattgcca gttcaagtaa agtgagatga gagcatgtta
     6121 aattttttta gaaaaaatga aataagcgtt gtagcacctg caaccggtgt ttttgaaaaa
     6181 ctggagaaat taagtgatcc agtcttttca aaaggaatga tgggacaagg atttgcaatt
     6241 gatgcaaaaa acgaaacgat tgtatctcca atcgatggtt ttgtttcaag tatttttcct
     6301 acaaaacatg ccttaggaat aaaaacaaaa tcaggaattg agatacttgt tcatgtagga
     6361 atagatacag ttgagctaaa tggtgaggga tttgatatta aagttcaaga aggacaaaaa
     6421 gttaaggctg gggatattct tatgaccatt aattttgtag tttttgaaaa gaatcacaag
     6481 actaaagatg tcattgttgt ttttccagac taccaagacg aaattttcat tccgaaactt
     6541 gaagaagtaa aacaaggaca agaattgttt gttcttggct aatgataagt aattaataat
     6601 agaatcgagg aaaatgtatg gtttttgggg ctattgaagc tggtggaaca aaatttgttt
     6661 gtgccattgg agataaagat ttgaacatat ttgaaaaagt cagctttccc acgactacac
     6721 ccaaagaaac aatgaattta gttttagatt tttttaatca tcataaagat gatttagaag
     6781 gtatcggagt gggatcgttc ggtcctattg atattcattg tgaatctaaa acgtatggct
     6841 tcattacatc aacgccaaaa cttgcttggc aggattttga ttttattgga agtttaaaaa
     6901 agcaacttaa tattccaact gcttggacga ctgatgtaaa tgcctcttgc tatggtgaat
     6961 atgtttctgg aaatggcaga ggcctttcaa gtgttgttta ctataccgta ggaacgggca
     7021 taggaggtgg cgctatccaa aacggaaact tcattgaagg ttttagtcat ccagaaatgg
     7081 gacatatgct tgtaaaacga cacaataaag acaacttttc tgggacatgt ccattccacg
     7141 gagactgttt agagggctta gctgctggtc cggcaatcga aagaagatca gggaaaaagg
     7201 gacaagaagt gactgaaaat gacgttactt gggaaataga agcttattac attgctcagt
     7261 gtgcatataa tacaacattg atgttatcac ctgatgtcat tatatttggt ggcggagtaa
     7321 tgaaacaaaa acacttaaaa aagaaagtac aagataagtt tattgagttg atcaacggat
     7381 atgtcgctat tcccgatgtt gacaattata ttatgacacc aaaattgtta gataattctg
     7441 gtattgtagg ttgtttagct ttagcaagag acgttaaaga aaaatcttaa tttggaaaaa
     7501 agatcgtctc gactatttgt ttggttgatg cgatcttttt tttcaattag taattgaagg
     7561 gacgcctaaa agtgaaaaaa aaaatgaaag atgaagtatt agagtatatc aaaaataatt
     7621 taaagtatta cgatttttct gctcaagata ttgcaatgaa attttgtatt aaaagaaatg
     7681 tcgcttccca ctatttgaat cagttatttt cagatggaaa attactaaag aatgattctg
     7741 ttagaccagt aatgttcaag tataatcaac aaaagccaaa agactgcttt tctaagttta
     7801 ttggagcaga catatctttg aaatccacta tagataaatg caaagctact gtaatgtatc
     7861 cccctaatgg cctcccatta ataataaaag gaaacagtgg cgttggaaaa agttttttag
     7921 caagtttgat ctatcagtat gctcttgata gaaaagtaat tcataatgac gcaaaatttg
     7981 ttgttgtgaa ttgtgcagat tatgcaaata atccagagct attgtcagca gttttatttg
     8041 gatataaaaa aggagccttt actggggctg aaaaagatac tgcagggatg ctatcttctg
     8101 ctaatggagg ataccttttt ttagatgagg ttcacaatct aagtgcagaa aaccaagaga
     8161 aattgtttct tcttatggat tctcaaaagt atcgtaaact tggtgaaagt gtgcaatggg
     8221 agtatgcaaa tgttcgcctt atcttagcca caacagaaga taaaaatacc tctttgttag
     8281 caacttttag aagacgcatc ccagctgaaa tcactctgcc agattacaat aatagaagta
     8341 catctgaaaa aattcaatta ttatttgaat ttcttaaaga tgaagcaatt acaattgatt
     8401 caaaaatatt ttgttcgatt gaacttttta ctgatctttt atcgaaaaca tttgaaggaa
     8461 atgttggaga attgaggaat gaaatcaagc ttctttgtgc agaaggttat ttaggaaata
     8521 agagaaagtc ttcaatttat ttaggggaca aactagacag cggtttttgg atagatccag
     8581 aaattagtat agatttaaaa aaaatgtttc ttaaatcact ttctgaaatt gatttgattg
     8641 aactttttca aaatcacatt tcaattgaag aaagcatgag tcaattaaga gatagaatac
     8701 ttaaagagtg tgcaggttct tctgagtata attatttaga aagtgacgaa tttatagcat
     8761 taagaaacta tgttgttaat aaaatatcac caattattga ttcgacaggt ctatgtttat
     8821 tagatgaatt cttggcggat atcagtctat ttataatgtt tattgatgta attgaagaaa
     8881 catcaagaaa ttttttgctg tctaagttca gaaaatttcg tatgaaaaat gataaacaaa
     8941 aattattggc aaatgagatt tggagtagtt tagaagtcga agaaagtaaa caagaacttt
     9001 tgttgaaatg gatacttttt cttgtaaaga agttctatgt gaaaatacca gaaacccatt
     9061 gtctgatagt tatgcacggt aaaataacag cttctgcgat cgcaagggaa acaaataagt
     9121 tgctgaatac atatgtttat gaggctttcg atatgccaat tgaaggtgag actagtgact
     9181 taattaacct aatcaacaat ttttgtaaaa gtatagatac gacgaatgga ctcattctgc
     9241 tagttgatat gggatcattg gaacaaatgt atgaaaaaat tgaatccaat gtaataggtg
     9301 atttggtaat tttaaacaat gtttctacag ctttagcgat tgaatgtggg attcaagttt
     9361 gccaaaaaaa gccaattagt catttttacc agatggattt tgattcgttt caagttaaag
     9421 ttcagtatta taaaggatta tcacaaaaga aaaatgtaat agtatcttgt ctctctggtg
     9481 aggggatttc tgaaaaagtt aaggatattt taaaacggta tctcgataat caagtggaga
     9541 ttttgatttt tgattttaac gcattaaaga aaatagcaaa ggaaaaagat actatgattt
     9601 ttaagaatac aatttgtgtt ctttcaacca ctgaatttta cattcaagga atcgattgtt
     9661 taaatttaga aaatctaatt aatgggaatc aaaccttaga aaaattaaat aagtatatgg
     9721 actcggatag ctgtgagttc tgcttaaatg aattagttaa actctttact attgaaggcg
     9781 ctagtactaa gcttcgcttt ttagattcca aaaaagtatt caatgagata gaaaaagtac
     9841 tatatttgta tgaaaaatat tacgatgtca aaatcccaag ttttctgaga attaatctat
     9901 ttctacatct ttctggaatg attgaacgaa ttatgattgg tgatggaata acaaatgaac
     9961 atttgaaaga gggagcgcaa ctatttgata cttttttaaa tgtatcaaaa gatttttttt
    10021 cagaaatcaa agatatttac tgtattgaaa tacccaaagg agagtatgag ttaatctata
    10081 caatttttga gcagactatt ttctaaatag catactagcg tctaaaaaaa tgaaagggtg
    10141 tccaaagtat atttagacgc tcatttaatt aatatttact gtattttccc gctttattgg
    10201 ataatgttag ttggcacagt aattgcttat ataaaagtat aagaagaaag gagagaacaa
    10261 aatggcgttt tggcaaacat ttttagttgt gttgtatgga tttttcatta actgggataa
    10321 ggaagggccc aaaatcggaa cctcccaacc tgtcgttgca ggtttcttga ccggacttat
    10381 tatgggagat attcaaactg gactttatat cggtgggact ttgcaattaa tgacactagg
    10441 tattactagt tttggtggtg catcagtacc ggattatcaa acagcagcat tgatcggtac
    10501 ttatttagca atctcaacta accaggatgc ttctatagga ataactttag caataccggt
    10561 agcaatgtta attgtacaac tagatgttct aaagtggtca acaaacattt tttttcaaca
    10621 aaaggcagaa aaattcgcac aaaaagaaga ttatcaaaaa ttagagtgga tgcaatattt
    10681 ggcatcaatt aatacaagct ttgtatctgg aattcctgtt ttgttaactg tgatattagg
    10741 cccaacgtta gtgggaagtg caatcaatta tattcctgaa tgggttaccg gtggtttaaa
    10801 ggtagcaggg ggactattac ctgctgttgg gataggaatg ctacttaaat atttacctac
    10861 aaaagattac tttgcctatt tgttagttgg tttcgttttg gcagtttatt tccaaatacc
    10921 aattttaggg atttcgttac ttggcgctgc aatcgcacta atcgtatata aaaatagatc
    10981 aaataatact caagtagcac cagctgcaac aggaggtttt gacgaagatg aataagaaac
    11041 tgacaaaaat cgacaaacaa gtaattttcc ggtggattct caatggtgca acttcattaa
    11101 attatgaaaa aatggaaggg ttgggttatg cgtattctat gcttcctttt atcaaggaca
    11161 catataaaga tgatcctgaa ggaatgaaac aatccgtttt agctcaccta caatttttta
    11221 acactacgcc gtatacagcg ccttacatta ttggtatgaa tgttggaatt gaaaaagaag
    11281 aaaaaaataa gtctttggaa gcagtaagtg ctctgaaaac aggtctaatg ggtcctttag
    11341 cgggaattgg agatagtgta tttgtagtta ttccatggac tatttttgga gcaattgcag
    11401 ctaatatggc attggaaggt agttttgttg gaattatttt gtggatactg gcatcaattt
    11461 tattaaggat tactgcttat cctttatacc ttgctgggaa agaatcgggt gcgagcctac
    11521 taactcaaat tgaaacaaaa ttaaagtcta ttactgatgc agtatcaatt ttagggttaa
    11581 tggtggtcgg tgcactcatt gccacagttg taaaagtgaa tgttggcttt gaatttaaac
    11641 aaggcgactt aacaatgacc ggaaatgaaa tctttgatca agttatgcct ggtttattac
    11701 ctgcatgtgt agtagcaatt gtgtattatt tgttaggacg aaaggttaaa ccagtttatg
    11761 taattctatt aatcttagta gtttctattg cgttaagagc gttaaatatt ttgaagtagg
    11821 tgttgaatat ggatgaaaaa atgaaaggta ttatacatgt tcgtattgat gatcgaatga
    11881 ttcatggaca agtagcaaca caatggacaa atcaattgag tgctaacaga attatggtta
    11941 ttaataatga agtagccaat gatgacgtaa aaaaagctgt agttcgcctc gctgcaccac
    12001 ctaatgttag aacttcaata attacaaggg aagtagcagt taaaaatatt ctttctggta
    12061 aatatgaagg acaaaaagtt cttattgttg cagtttctcc aatcgatgtt aaatttttga
    12121 ttgataacgg tttaccaata acaagtgtaa acgtaggaaa tttatcaaga aggaatggaa
    12181 cagaacgcat ccgtccgacg ataaatatta ctgaagaaga gagagaggct tttaaagaac
    12241 taattagtga tggagttgaa gtgacagtga tacaaactcc tagagattca aaagaatttt
    12301 taaaggattt tatttattaa gaacagagga tgagtggatg gagtttataa ttacatctca
    12361 tggaaatatt gccattggat ttgtagatac attaaaaatg ttttttggcg ataatttaaa
    12421 ttgtcatgtg gtaacacttg gagatgcagg cattgaagaa ttccgtgaaa acattgaaaa
    12481 aatagtttct caagtaaaaa atcaagaagt tatggtattt gctgacttga ttggtggaac
    12541 acctttcaac gaatttgcta aaagaagtga agtatttcaa aatgggtttc aacttcttgg
    12601 tggcatgaat ttaggaattt tgattgaggc tgtcaatttg agattacaag gaaaaaaaag
    12661 cgatgatatc atcgaaaatc taagaaatat gaatacaatt gcgtgtcttg cagatatgca
    12721 aagacatact aacgaagagg atgagtgata aatgcaaaaa attttttaca agcctaaaga
    12781 tttttggttt ggggattgca tgccttttta taaagatgga actttttatc tatttcatca
    12841 acgagatacg agaaatccta aacctttaac tgatcctttt gggtggtcac tagttacaac
    12901 cactgatttt gtgaaatttg aagaatacgg ggaagtaatt catcgtggtg gcaacgatga
    12961 cattgatcaa tacatttacg ctggaagtat tgtccaagga atcaatgagt atttagcttt
    13021 gtatactgga cataatcgca aagctaagtt ggatggaaaa acttcagaag tgttaatgat
    13081 tgcaagttct aaagatttaa ttcattggaa aaaggatggc gaagcagcaa aacttgttcc
    13141 tcaagaagga tatgataaga atgattggcg cgatcctttt gcaatttttg atcaagatca
    13201 tggaaaatac gttttgatac taggagctag aaaaccagca agtaagaaaa agccgacggg
    13261 gagattggtc tattttgaat ccgaagattt aaaagattgg aatttcaaag gagactactg
    13321 ggctaataat gaatttaaca tgattgaaat gcctgatata tttgaaattg atggaacgtg
    13381 gtatttactt ttttcagagt attgtgaaga taaaaagact aaatatcgag tcggagcagg
    13441 attattttca gattggaaat caccagtaga cgaagctttc gacggaaaag cctattatgc
    13501 agcaagaaca gtcggaacta atgaaactgg ccgttttcta actggctggg tggcaacaaa
    13561 agaaggggag aacgatcaaa ataactggga ttggggcggt gcacttgttc cacatcaaat
    13621 tattcaaaag acagacaaaa ctcttggtgt taaactgcct gaaaaaataa ttgagaattt
    13681 taaagaaatc actccatttt caagttttaa gttagagaaa gaatttggaa aaaaagaaag
    13741 agtaattgtt cctaaaatcg aagattattt tctatttgaa acaactttga ctattacatc
    13801 gttaacaaag gagtttgctt taaaattatt tgtagatagt gatactcaag aaggatacga
    13861 atttcgtatt tcattgatta ataatcagct tactttcgga aaaactccga actatccttg
    13921 gcctcaaatg tttgataagg ggctgcaacg accactattt ttggaaatag gcaaagaata
    13981 tgaactaaag ttaattgttg atgatacgat agctgtttta tatattgata atgttgcttt
    14041 aagtactaga atgtatgata aagtcggaac agcattaagt atgactgtta cggagggagc
    14101 aatcaaggta gataaactag actattcaat aaattatgaa tgtggatttt aaaacaattg
    14161 aagggatgat gtaagtgaaa ttaaatggtt tacaacatat tggaattcca acaaaagatt
    14221 ttggagcttc aaaaatcttt tatgaatcct tagggtttag tctgattaat gaagaaatga
    14281 atgtgggaag taaagtcggc tttttcgagt tgaatggaac gataatagaa atatgggaag
    14341 ataaaactac tgagtgtaga ggagccattg atcatctagc attagatacg gatgacatag
    14401 atgaggtatt caattcaatt caagatttag gatatgaatt attagataaa aatattatgg
    14461 aattaccgtt ctgggaaaat ggaatccgtt actttaattt ctacggacca aatcatgaga
    14521 ttatagagat aagccaaatg aagaaataaa tagataacga agtgctctaa gttggtatga
    14581 acgaaaagta cttcattttt tggtatcagc atttcaatag tttaatgaga atttactatt
    14641 tcaaattaat tcaaagtgac agtatttttt acttatttgg tttcaaattt tgtaatcctt
    14701 cctatttatt ggaatacact ccacattttg tatacaagtc atatcatgtt ttagcaaagc
    14761 tcttaccaag caaagttata atgatgtttt ccaaagtttg atctttcgat ggaggctaac
    14821 acatattttt tgcaggacag ccaaaattag atgtatagaa tagagtctgt gaggcgtata
    14881 gacagtttat tgtctgtatg ccttttttta ttttgaaaaa tttttagtat ttttcgaaaa
    14941 atgctcactc ctagagtaag cgccccatag aacagtacct tactaacaaa tgcacctcaa
    15001 gatatacttg agctatcaag aagtctggag gttttc
//
LOCUS       DAJSMK010000057        14774 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.059, whole genome shotgun sequence.
ACCESSION   DAJSMK010000057 DAJSMK010000000
VERSION     DAJSMK010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14774
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.059"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(12..287)
                     /locus_tag="ON488_001791"
     CDS             complement(12..287)
                     /locus_tag="ON488_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231984.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            581..1396
                     /gene="thiD"
                     /locus_tag="ON488_001792"
     CDS             581..1396
                     /gene="thiD"
                     /locus_tag="ON488_001792"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HCR3231985.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1725..3176)
                     /gene="cls"
                     /locus_tag="ON488_001793"
     CDS             complement(1725..3176)
                     /gene="cls"
                     /locus_tag="ON488_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HCR3231986.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3517..6183
                     /locus_tag="ON488_001794"
     CDS             3517..6183
                     /locus_tag="ON488_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCR3231987.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6547..7299
                     /locus_tag="ON488_001795"
     CDS             6547..7299
                     /locus_tag="ON488_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3231988.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7321..8475)
                     /locus_tag="ON488_001796"
     CDS             complement(7321..8475)
                     /locus_tag="ON488_001796"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HCR3231989.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8660..11101
                     /locus_tag="ON488_001797"
     CDS             8660..11101
                     /locus_tag="ON488_001797"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HCR3231990.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11431..12135)
                     /locus_tag="ON488_001798"
     CDS             complement(11431..12135)
                     /locus_tag="ON488_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231991.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(12322..12567)
                     /locus_tag="ON488_001799"
     CDS             complement(12322..12567)
                     /locus_tag="ON488_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231992.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(12584..13435)
                     /locus_tag="ON488_001800"
     CDS             complement(12584..13435)
                     /locus_tag="ON488_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HCR3231993.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            13601..14605
                     /locus_tag="ON488_001801"
     CDS             13601..14605
                     /locus_tag="ON488_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HCR3231994.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
BASE COUNT         4752 a         2591 c         3068 g         4363 t
ORIGIN      
        1 acagttagaa gttaaaattg ctgattcaca tagagtttat gacttcttgg aaattctttt
       61 tcaatcagtt ttttcatctg tttatgaaat tctttttttt cagtaaacat aaaggtttgg
      121 gtatcgtaac cttcttcatg taggaaatag attattcctt tttctgtgtt ttgcgtataa
      181 gcttttatac tcctgtcttt tttgaaagaa cagatcgtat agccatctat ttggtctggt
      241 agtcgtttga ttttcttcaa aatgactttt ttatcctcaa gtttcatttt tttcacctga
      301 ctttattttt ttcatatgga aatcatagcg cctttggtta tatgaaaaca agaaggatac
      361 tgaaatatat ataaatcaaa tagtggttat ttattattag aatagcgaat acaaataaac
      421 gaccactatt ttctgattta ttgcaaatgt tttttcaaat aaatttgatt accaagaaaa
      481 ggtagtggta tatttactga gggatacttt gaaaaacata tgatagaaac agtaacagta
      541 ttatgaaaaa tctttttata aaaatggagg aatcgatttg atggaagatc agtatgtaca
      601 agcaatgacg atcgcaggat cagatagcga tggaagcgca gggatgcaag cagatatgca
      661 tacattcttt acaagaaatg tttacggtgt ttctgtcatg accgcatgtg ttgcaggtaa
      721 ttcttacgga atcggagcaa gtgtgacatt gccaacagat tttatcgaca aagaatttga
      781 actgattgcg aaggactttc aaatacgtgc agctaaaaca ggtatgctag cagattcaaa
      841 gttgattgag acagttgtaa aaaattacca aaaatatgat tttggaccat tagtcgtgga
      901 tcccgtaatc gtaacgaaac atggaaatct tttactagaa gaatctgctt tgcaaagctt
      961 gaaagaaaag cttgtccctt tggccgaagt actgacacct aatttttatg aagcagaaaa
     1021 gctgactgga cggacattag cagctgaaga agattttgtg caagcagcaa aagaactgca
     1081 agatatgggt gcaaaaaacg ttatgatcaa aggacatcat gctaaaaatg cgcagcaaga
     1141 aacagtcaat gactacgtat tgttcgaatc aggaaaatca ttttggttaa atgcaccatt
     1201 ttatcctacc gaccggatca acggaactgg cgattcgcta tctgcatgta ttgcagctga
     1261 gttagcgaaa ggaaaaacag ttgaacaagc gatccgattg gcaaaagact atgtaaaccg
     1321 tgcaattcgt gaagaaataa atgtagggca caaatatggc cccatcaatc attgggcagc
     1381 tggtgaatta gagtaaaaga aagaagttgt gaaaaagttg ccctgcatca agtaataaga
     1441 acagccaagt aaaaacagct tcttatgttt ttaacttggt tggacttatt accgcagatg
     1501 caagcttttg aacaccgttt aagaaagagg tcgtgagcct gccgtccagc tccgagtcac
     1561 aaggaacaag ttcaaaaaac agcttctcat gtttgttgaa tattgtgact tgtgaccgag
     1621 gagttggcag gagaacaccg tttgttcgga agaagggact gtgacaagat ttttgtcaca
     1681 gtccctttaa tcttagtata tttttctcta cttgaataaa aaaattatag gattggagaa
     1741 aataatcgag aaatttgttg cttgaataat agccagttag acatttcctt gactgtttca
     1801 gttgtcatgg atgaacaatg tgtctcatct tctttgaact gagtagcaag ttcttctaaa
     1861 aactcaggat cgtaaatgac agcacttgtt tcaaaattca atcggtagct acgaatatct
     1921 tgatttgctg aacctaccat gcagatttca tcatccatta tcaatgtttt tgcatggagg
     1981 aagccgttct catagacaag gatttgtaca ttttccttga tcagctgccg agcataatat
     2041 tgtgttgctc gataaataaa aggatgatcc ggtttgttgg gaatcatgat tttcacatct
     2101 acaccagagg cagttgcgat ttttaaagca gcaatgacac tttcatcagg aacaaggtaa
     2161 ggtgtctgta tccaaacacg ttttttagca gaagtaatca atttgataaa tgaaagcttg
     2221 atttgttccc tttcgttatt cggtccgctt gaaacaagct ggatggatgt atcagcaagc
     2281 ttagattcat ctcgatctgc ttttttaaag aaataattca aatgatagcc gacctttttt
     2341 tcttcaggta ccgagacgtt ccagtctgtt aagaagcgaa gctggagcaa agaagaagcg
     2401 gcaccgaaaa tccgtatatg cgtatcgcgc caatagccga atttttttgt tgtatttaca
     2461 tattgattgg caatattgaa accaccggta taactaatct ttccatcgat cacaacgatt
     2521 tttcggtgat catggtaatt caatcggaaa cgaagtaatg ccctttgtga ggtaacaaat
     2581 gtatggacat gtccaccatt tttgattaga cgattgaaat cttttgcttt tgtgccatga
     2641 gagccaaatg catcatataa tattcgaact tccacgcctt ctgcggcttt ttcttctaaa
     2701 acatgtaaga cttgctggcc gatattatct gtcacaaatg cgtaatattc gatatggatc
     2761 gaatgtttgg ctttttttag atcttgaagc agtgaatcca atttctcttg tccgtctgtg
     2821 agaagagtga cagaattcat tcttgtcagc ggcatacgat ttaatgaaga gaagaagtca
     2881 acaaattgct gtttgtcttt atcgcccatg tcaggatcgt aatgttcaat ggtatctcct
     2941 ctaaaagact gaaagttttc taattctttc aagtcacttt gtcggagata gaattttttc
     3001 ttatccgtta atccacgtcc gaaaaataaa tataatacaa agcccacccc aggaagggca
     3061 aacaatacta agagccatgc ccaaatggct gctacatctc ggggtttgat caaaatagcc
     3121 accaaagcaa taagtgcatt taatagataa agggcggtta taatactaga taccacaaaa
     3181 atgttcctcc ttacatacaa taacattagt atagcatgat agaagaaaga agcctaccaa
     3241 ggtgaatata cttttcactc ctttcatgaa aatgtaggta aatcgggcta aagtagttgc
     3301 tttttgtagg ttaataaggt aggatattag tacagttgaa tatctcctta ggggagtaac
     3361 cggcaacgtt tgttgcgata atatcaacag taagttaacc aaatggtttt ctggtattgt
     3421 atgaaatggt gagacctaag acaaatgcgt atttgtctta ggtctctttt ttttcagaca
     3481 ggactagggc caagatcaaa aaatggggga tgaaatttgg aaaacaagga acaagcacaa
     3541 caagcggtct ataaagaaac gatcgactcg ttgatgcagc aaacgcagag ctcaaccgat
     3601 ggattgagca ccacgcaagc gaaggaaaaa ttagaaagag atggcttgaa ccagctaaaa
     3661 gaaaagccga agaagccaac ttggaaattg ttcttagaaa ctttcaaaga tgcaatggtt
     3721 atcgtattgc tgattgtcgc actgattcag atggtcatgg gtgactacat cgaattctta
     3781 gttatttttg cagtattgat gttgaattct ataatcagtg ttgtccaaac aaaaaaagca
     3841 gaaggttctt tagaagcgtt gaaaaacctt tcagcgcccg atgctcgagt gattcgtgat
     3901 ggtaaggaaa aaacgattcc ggcaaacgaa cttgtggtag gagatatcgt gttgttagac
     3961 gcaggcgatt atgtacctgc tgatggacgt ttactagatg cgggatcatt aaaagtagat
     4021 gaaggtatgc tgacaggaga gtcgacttct gcagaaaaag aagtaacgga tatcacaagt
     4081 acggtaccaa tcggagatcg tacaaatatg gtattcagtg gaacgatcgt aacttacgga
     4141 cgcggtaaat tcttagtgac ttcaactggg aataatacgg agatcggaca agttgctggc
     4201 cttttggaat caacaactga gcaagtcact ccgttacaac gaggtctgga taaattcagt
     4261 aaaaaactaa gtttggctat tttggcattg tctttattga ttttaggtat ccaactgttt
     4321 cgtatttatc ttggagaagg tacaggagat atgactgcag atatcgtcag cgcagtgatg
     4381 tttgccgtag ccgtagccgt agctgctatt ccagaagcat tacagtctat cgtaacaatc
     4441 gtgttatctt tgggaacgaa taaaatggca aaacgtcatg ccattattcg gaagcttcca
     4501 gcagttgaaa cacttggttc gacaagtatc atctgtacag ataagactgg tacattgaca
     4561 caaaacaaaa tgacagttgt tgactacttt ttaggtaatg gcgatactgg ggatttcaca
     4621 aatgaccctt caaaatggac agctgacgaa cgtcgcttga tcgaaatcag tgttttagcg
     4681 aatgatgcat cgatcagtga agacggtact aaattgggcg accctacgga agtagcgttt
     4741 atcgacttta gtgaaaaatt aaaccagcct tatcaggaaa tccgaaacaa ctacccaaga
     4801 caagcagaac ttccttttga ctcagatcga aaattaatgt ctactggaca cacaattgat
     4861 aacaaaaatt acttgtttgt taaaggcgga ccagatatcg tcttccaacg cagtaaaaaa
     4921 gtattgctaa atggtgaagt cgttccgatg acggatgaat tgatgaaaaa attccaagag
     4981 caaaatgaag ctttttcaac acgcgcatta cgtgtactag cttttgctta ccgtccactt
     5041 gataattttg atttatcatt tgaagatgaa gacgatttga tccttgttgg tttgcttgct
     5101 atgatcgatc ctccacgtgc tgaagtgact caggcggtaa cagaagcaag aagtgcagga
     5161 atcaaaacaa tcatgattac tggtgaccac aaaacaacag ctgttgctat cgcaaaacaa
     5221 atcgggattt ttgaagaagg aaacctggct ttgaccggga cggaactaga tgaattgaca
     5281 gaagatcaac taaacgaagt tttagaaaaa gtcactgttt atgcacgtgt ttcacctgag
     5341 aataaaattc gtatcgttcg tgcttggcaa aataaaggtc atatctcagc tatgacaggt
     5401 gatggtgtaa atgacgcacc agcattgaaa caagcagaca tcggaattgc tatgggaacg
     5461 ggtacagatg tggcaaaaga tgcagcagcg atggtattga cggatgataa ctttgcttct
     5521 attgtcagcg cagtagaagt aggacgtaat gtgtttgata atatcaagaa agctatttct
     5581 tatctatttg caggaaattt aggtgcgatc attgcgatca tctttgcctt agttgctgac
     5641 tggtccaatc catttacagc attacaactg ttgttcatca atttagtcaa tgattcactg
     5701 ccagcaattg cattaggtac agaaaaagct gaacctgcta cgatgaaccg cccgccaaga
     5761 gatccaaatt caggaatctt tacggacaaa acattgattt ctgtaacgta tcgtggtgtg
     5821 ctgattggga ttgctgttat ctttgctcaa tggcttggca tgcagcattc acctgaattc
     5881 ggtgtagcca tgtcattttc aacattgatt tggtgtcgga cattgcaaac attcccagca
     5941 cgttcaaaca cacaaacagc tatccaagca gggttcttct ctaacagaag tgtcttacta
     6001 gctgtagttg tatgtagcgc gctttactgc ttaacaatga tcccaggact gaaagaagtc
     6061 ttctctatcc catcagcatt tggattgaca gaagtcttta catgtatggg aatcgcactt
     6121 gtgacaattg ttttgatgga aatcactaaa ttgatcattg tacgagtaca aggaaataaa
     6181 taaaacgaat caacgaggtt gtgagcctgc cgtttaattc tgagtcacaa ggtgcaattt
     6241 caacaaacag cttctcatgt ttgttgaata ttgtgacttg tgaccgaaga gttggcagga
     6301 gaacaccgtt taaggaagaa gttgtaaaat cagcattttg agctaatact gagggtcatc
     6361 tgattggaca ctgtttattc ggaaagaggg actttgacac gactttggtc acagtccctt
     6421 tttttattta tgatagacgg aaagccaatc attttattat tcatcaaaag agatagaata
     6481 gataaaagag gagaatgatt tattccgaaa agtgaaaaca tataacaaaa aattagagga
     6541 aatcaaatga atgaaaaaga atgggatgaa tttgctgaag aatattatga aatccagcaa
     6601 gaatcgcaag taactattgc tgaagatgta aaaaattatc tgaaaacgga gaaagtcctg
     6661 cctgctgaaa cagcagcaga cgttgctgga ggatctggca gatttctttc cttagcaaaa
     6721 gaaattaatc gctatgattt gatcgatttt tcttcaggaa tgctagaaaa tgcaaaaaaa
     6781 gaagcagaaa aaaatgagtt gccaaatgtt tcctttatca aacagtcgtt agaagaattt
     6841 atccaatcaa atgagacata tgaaatggtt tttacagcag caaatccagc attggtacat
     6901 cttattcaat tagaaaaatt gatgaaaaag tcaagcaaat ggtgcgtgat aatcagagta
     6961 gtggaatcaa tcgatgatgt tttttatcct atcgaaaagc aactaggaat gatagaagaa
     7021 gatcctaata catcgccagt tgtaatggat caatttgaaa catacttaat tgatgaagga
     7081 ttcaaagtga agaaaaaaga ttttacttat tttacacagg aatcaattac tgaagaattg
     7141 atgaagctat actatgacgc gtacgcaaaa gatcctgttg tgaccaggta cattcgcaaa
     7201 ctattcagtg aaaaacgaga aatccttagt acgactaagc tgacctatag actgctcctt
     7261 tggtccgcag ataaaaaaag aacctttcac gactcgtgaa gggttctttt tatgatttta
     7321 ttatattttg tagtaacgaa tatcattttc gatctttgta atcgaaaaag gtacatctga
     7381 agtatattct gcacattctc cgtgttcagg aagcgtctca ctgaaaatcg tttcatattc
     7441 gtcaacagtg atccgtgttc gagaatctag catctcttga tgagattgtg cgaagagata
     7501 ttcttgatag ttttcttcca gataacctgt aaaaaattca cttactgcac cagaaccgta
     7561 gctgaataga ccgatgcgat ctcctggctg tagtgatttc gaattttcca gtagagaagt
     7621 tagccccagg tataatgaac cagtgtaaag attaccgatt cgtcggctgt aacggatgct
     7681 ttcttcatag cgagccataa gacgttcctg attttcttcg tctgtttggt ctaatacgct
     7741 ttgcaatgcc ttttttccca tcttagtata cggaatatgg aaagcaatcg cctgataatc
     7801 ttcgagtcct cgacccgaca attctttatg tcgattccaa actttttgga atgattcgat
     7861 atacgtagaa ttagataaag gaccatcaac aacaggaaat tcgctataat ctggacgcca
     7921 gaaatcatag atatcttctg tcagaaatac gctgtcgtct tcaatcgata aaatacgcgg
     7981 gttttgagtg atcatcatcg caacagcacc gacaccttgc gtcacttcac caccgcttgc
     8041 caagccgtaa cgagcaatat cacttgctat gactagtact tttcgttctg gatgattttt
     8101 gacatattct ttcgccatgt gcaaagctgc ggtgccaccg tagcaagcct cttttacttc
     8161 aaaagaacga gcaaaagatt ggattttcag taaatggtgg ataattaccg cactcgcttt
     8221 tgaatgatca atcccggatt ctgttccgac gatgaccatg tcgattagct cacggtcttt
     8281 ttctgttacg attttgctgg cagcatttgc tcctagtgta atgatgtctt catttgcacg
     8341 attgactgcc atttggtctt gaccaatccc tatatggtat tttgcaggat catccccacg
     8401 gctttctgcc aactctgtca tatctaaata taaattagga ataaaaaagg aaagacgatc
     8461 aatccctatt ttcatttcaa cacctcttta cttatgataa aaaacttact ttactaaggt
     8521 atcataaaaa gattaaaaga aatataaaaa agagaatatt taaggattgt taaaatttaa
     8581 tcttagaaaa aaataactgg aacaagagct atttgttttt acagcaaaga atggtatatt
     8641 tttgtaggag gtggcttact tgaaagaagt cgttatgata gatgctgcaa gaacgccgat
     8701 aggaaagtat cgcggaagtt taagtccatt tactgcagtt gaattaggca cacttgtgac
     8761 taaaggatta ttagataaaa caaaactgaa aaaagataaa atcgatcaag taatatttgg
     8821 aaatgtcctg caagctggta atggtcaaaa tgttgccaga cagattgctt tgaacagcgg
     8881 tctccctgta gatgtcccag caatgacgat caatgaagtt tgcggatctg gtatgaaagc
     8941 agtgatctta gcacgccagc tgatccaatt aggtgaagca gaacttgtga tagccggcgg
     9001 aacagagagt atgtctcaag cacctatgct gaaacagtat cagtcagaaa caaatgaata
     9061 tggtgaacca atttccagta tggtcaacga cggattgact gacgcatttt caaatgcaca
     9121 tatgggatta accgcagaga atgttgcaac acaattttct gtgagcagag aagagcagga
     9181 tcgctatgcc ttgtcgtccc agttgaaagc agcacatgct gtcgaagccg gtgtattttc
     9241 tgaggagatc atcccagtca agatttctga tgaagacgtg ttatctgagg atgaagcagt
     9301 tcgtggaaat agtacattgg aaaaactggg cacgttacgt acagtattct cagaagaagg
     9361 aactgtaaca gcaggaaatg cttccccgtt gaatgacggt gcctctgtgg tgatccttgc
     9421 atccaaagaa tacgcagaaa ataataatct gccttattta gcaaccatca aagaagtagc
     9481 ggaggtcggt attgacccaa gtatcatggg aatcgctcca atcaaagcca ttcaaaaatt
     9541 gacagataga tcaggaatga atttatcaac aatcgatctt tttgagatca atgaagcatt
     9601 tgcagcttct tctatcgtag ttagccaaga actgcagtta gatgaagaaa aggtcaatat
     9661 atatggagga gcaatcgcat taggccatcc aattggtgca agcggtgcac gtatcttgac
     9721 tacattagct tacggattgc ttcgtgaaca gaagagatac ggtattgctt cattatgtat
     9781 tggtggaggt ttaggcttgg cagtcttgtt agaagcgaat atggagcaaa cacataagga
     9841 tgtgcaaaaa aaaaagtttt atcagcttac gccatctgaa cggcgcagtc aattaataga
     9901 aaaaaatgta ttgacacaag aaactgcgtt gatttttcag gaacaaacac tttctgaaga
     9961 gctctccgat cacatgatcg aaaaccaagt gagtgaagtg gaaatcccaa tggggatcgc
    10021 gcagaatttt caaatcaatg gcaagaaaaa atggattccg atggcaacag aggaaccatc
    10081 tgtcattgca gctgcaagta atggtgcaaa aatctgtgga aatatctgcg cagaaacacc
    10141 tcagcggctg atgcgagggc aaatcgttct atcaggaaaa tcggagtatc aagcagtgat
    10201 caatgcagtt aatcatcgaa aagaagagct gattctttgt gcaaatgaaa gttatccttc
    10261 aatcgtgaaa cgcgggggcg gtgttcaaga tatctctact cgggaattca tggggagttt
    10321 ccatgcatac ttatctattg attttttagt ggatgtaaaa gatgcaatgg gcgctaacat
    10381 gatcaactcg attcttgaga gtgtggcaaa caagttacgg gagtggttcc ctgaagaaga
    10441 gattctattc agtattttaa gtaattttgc tacagaatca ttggcttctg cctgttgtga
    10501 aatcccattc gaacgcttag ggagaaacaa agaaatcggt gaacaaattg ccaaaaaaat
    10561 ccaacaggca ggggaatatg cgaagcttga cccttaccgt gcagcaacgc acaacaaagg
    10621 gatcatgaat ggtatagaag ctgtagtggc agctacagga aatgatacac gtgcggttag
    10681 cgcttcgatc cacgcctacg cggcaagaaa tggattatac caaggattaa cagactggca
    10741 gatcaaaggg gataaactag ttggaaaact aacggtgcct ttggctgttg ccacagtagg
    10801 cggagcttcc aatatcctgc caaaagcaaa agcatcttta gctatgttag atattgattc
    10861 agccaaggaa ctagcacaag taattgctgc agtagggtta gctcaaaacc tggctgcttt
    10921 gcgtgcatta gttacagaag gaatccaaaa aggccacatg ggacttcaag ctcgttcatt
    10981 agcgatctca attggggcta ttggtgagga aatcgagcaa gttgcgaaaa aattacgtga
    11041 agcagaaaag atgaaccagc agacagctat acaaatattg gaaaaaatcc gggaaaaata
    11101 aaaaagcaat atctttagaa gaataaagca agatttacag ttattttatt tactgcagat
    11161 cttgcttttt tctctatcag aaaatatgtt tattattaga attttttata gttaaggtta
    11221 ggcatcttaa gaaatcaggc aactccaaga tatcttcagg tagaagagaa gtcgcctaac
    11281 attgtaggat cataggtgat ttgttggaca ggtcaagctg atatttgagc ctgatgttag
    11341 aaggaatttc tttttacttg ctgtagaaat tattatatga ctaaaaaggc tgggatttta
    11401 aatcccagcc ttttatgaca aatagaattt ttatcgatca gtaatcgctg tcgctgcaaa
    11461 ttgttcgatc aaaggaatca aagtcaattt gactttgtat ttccgttcga gtgctttttc
    11521 gataacgaac tcattttcag tagtcataga aatagttgct aatttacgag gttcatcagc
    11581 atttttttca ttaataacta cttcatgttc attttgttct gtgtaaaatt taggatactc
    11641 agcaacggct tttgaaaaat cagcaaaact taaagcggca ttcgtatcag ttgagcgtgt
    11701 attttcagtt gtgtccgctt ttggtttttc cgttttttct tctggcacac tgactgtttc
    11761 ttctgtaact ggtgtcgcaa cagcttgcgc agttggttca tcgtttttca atcgttgatc
    11821 attccagtaa gacacgattt caataagaag attgtcacgg aatcgttcga aaatcccgtt
    11881 ttctcctgaa cgaattctct ttaatacagt attgaagttg tcatcgattg gcacgttgat
    11941 ccgtgtatct tcatttgttt tcccagctaa tccgatcgtt aagatttgac ggtttttggg
    12001 atcaagcatg acttgtaacg gcaaaccata acgtcgcaag ctctcttctt ctagagaacg
    12061 gaataattgt cctcttacac catccaatga aggacggaat tgatttaata atttttgttt
    12121 ctgttttttc ttcatatgtt ctctccttcg ctcataccct ttcgattata agaaaaaaac
    12181 agccaaatga aaaggagtaa tgcaaaaaaa cttgcgtata cgcaaattac aacagaaaaa
    12241 tttgcgtatt ttcccgtttt ttgaaagaaa aataaaaaat ggaacggatt atgtatatat
    12301 acataatccg ttccattctt tctatttttt cggtatcaag gcaaaaacag gtagttcagg
    12361 tgaataaatg acttcatgtt cgtgccaggg tttgaccatt agcgaatgat cgaaccgttt
    12421 tttcagttct tcgatgattt gatcatgtgt ccagtttctt gcaggaaaat gttggatttt
    12481 ctctgcatcg atcaaaaaga caaaatcgga atgaaaagtc tgggtaactt cttccgagag
    12541 agaattcaag cgttcgattg gatccataaa atcacctttc gacttaaaat tgggtagtat
    12601 ctgggtcttt tgctttgccg actacaccat ctaactgatc gatttgtttc atttcttctt
    12661 ctgttaattc aaaatcaaat aattcagtat tttctttgat tctgcttggt gtcactgact
    12721 taggaagagg aaggaattcg tgttgcagcg accaacgcaa agcaacttgt gcaatcgtct
    12781 tgtcatgtgc ttcagcgatt tgtttcattt caggcacatc gaagatttta ccagtgccta
    12841 atggactata tgcttcgagg atcatatcat gtttttttgc atactcaact acagttgtct
    12901 gtaattcgcc tggtgcaagg aaaacttgat tgaccatcgg cataattttt gctgtttttg
    12961 ctagtgtatc tagatggtgg ggtaagaaat tgctcacacc gattgctttg attttacctg
    13021 cttcatacag ttcttcaaat gctcgccatg tatctgcatt tgcttgttcc caattatcac
    13081 gaaaagcaac agggtttggc cagtggatca aaaacagatc taaataatct gtttggagct
    13141 tcttcaatga ttcttcaaaa gaagacatca caagttcata gctgtggttt gcattccata
    13201 attttgttgt caagaatatc tcttctctag gaattccact ttccttaatc gcttggccga
    13261 cgctttcttc attcttgtat ccttgggcag tatcgatatg gcgataacct gcagccagcg
    13321 cttctttaac agaggaaaca gcgacatccc catcaggtgt ttgccatgtg ccgaatccta
    13381 ctaccgggat ttcgtaacca tttgatagac gataagtgct tgttaatgaa ttcatacttt
    13441 cagctccttt tttattcgtt caactataag tgtagcgcat ttttcgaaaa aaagaatcca
    13501 ttttgtttct actcttgaaa tttttgttta aaagaaaatg attttgattc tggtattttt
    13561 gatttttttt ccgtaaacta agacagaagg gaatgagaaa atggatatct atttaaaaaa
    13621 agcaattctg catattattg acagagaaac tggttctcca gtcttttcac aaaaagagct
    13681 ggatctgaca aaagaatata ttcgtgattt tcttcaaaag aagatccaaa aaatctcttc
    13741 tgctcaaaca aaaactggac aactagcaga agaaagcatg atcgttgaat cacttaaaat
    13801 cgctcaagaa aattttgtgg aagcaagtga agcaatcgtt cagcggtggt tcgatatcta
    13861 ccaagaaagt gaagaagcac ctagtgcaga tgtatttgtt gtcttgtatg aattagatac
    13921 agtgatgtac ttatctttat tgaaagtcaa ttatcgtgag gcttacactc actttgttga
    13981 agcagacgaa gcagggatcg acaaccgctt gattttgaat cgagcaattc taggggcgaa
    14041 aacacaaaaa gcagatgaag cattcgctgt gaatttgact gattggacct acgaattaat
    14101 tgaaaaaaaa tatgagtttt ctggcaaaaa agagctttat ttttctggaa gagtgatcga
    14161 aagtgttcct gcaccttctt tagaagaaaa tgtaaaagtg atccaaaaag tagccaagca
    14221 tcttggaaaa aaatttgaga cagaagaatt tgatatcatg gctgatttga aagaagctgt
    14281 ctatgatacg atagaagaaa aaggtcggtt ggatcatgag atgattgcgg aaaaagtctt
    14341 caaggaaaac atcacggcaa aaatggcttt taaagaagaa gtacaagagc aaggatttgt
    14401 cccagaagca cctcctgtaa aagaagtaca agaaatttct gagaaaaaat ttggaaaaca
    14461 aaaattcaag ctatcaaacg ggatcgaact gatcgtacca gtagatgtat atcgcaaccc
    14521 agatttgatt gaatttgtga ataatccgga tggtacgata tccgtgatga tcaaaaatgt
    14581 ggatgaagta ttgaatcgtt tataaaaatg actagaatat taggtgttca agtaccagtg
    14641 atcagttaaa tgaattgtgt caagagaagg atcggaaaag acgaatataa caaaaaaaga
    14701 gcgtgagaca aaagtaaaga acacttttgt ctcacgctct aaacacgtat aaacggcgga
    14761 agcagaagca actc
//
LOCUS       DAJSMK010000058        14529 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.060, whole genome shotgun sequence.
ACCESSION   DAJSMK010000058 DAJSMK010000000
VERSION     DAJSMK010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.060"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..301
                     /locus_tag="ON488_001802"
     CDS             <1..301
                     /locus_tag="ON488_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HCR3231995.1"
                     /translation="KKMFKSRDGITLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFN
                     VSDKGISSARKLLYVICSRAKNNLFLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            501..815
                     /locus_tag="ON488_001803"
     CDS             501..815
                     /locus_tag="ON488_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231996.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            836..1213
                     /locus_tag="ON488_001804"
     CDS             836..1213
                     /locus_tag="ON488_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HCR3231997.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            1223..1996
                     /locus_tag="ON488_001805"
     CDS             1223..1996
                     /locus_tag="ON488_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3231998.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            2018..3421
                     /locus_tag="ON488_001806"
     CDS             2018..3421
                     /locus_tag="ON488_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HCR3231999.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            3603..4787
                     /locus_tag="ON488_001807"
     CDS             3603..4787
                     /locus_tag="ON488_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCR3232000.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            4784..5074
                     /locus_tag="ON488_001808"
     CDS             4784..5074
                     /locus_tag="ON488_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232001.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            5071..5292
                     /locus_tag="ON488_001809"
     CDS             5071..5292
                     /locus_tag="ON488_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232002.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            5334..6113
                     /locus_tag="ON488_001810"
     CDS             5334..6113
                     /locus_tag="ON488_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HCR3232003.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            6180..6674
                     /locus_tag="ON488_001811"
     CDS             6180..6674
                     /locus_tag="ON488_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HCR3232004.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            6730..7368
                     /locus_tag="ON488_001812"
     CDS             6730..7368
                     /locus_tag="ON488_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232005.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            7440..7835
                     /locus_tag="ON488_001813"
     CDS             7440..7835
                     /locus_tag="ON488_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3232006.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            7819..10272
                     /locus_tag="ON488_001814"
     CDS             7819..10272
                     /locus_tag="ON488_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR3232007.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            10269..12296
                     /locus_tag="ON488_001815"
     CDS             10269..12296
                     /locus_tag="ON488_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232008.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            12293..13315
                     /locus_tag="ON488_001816"
     CDS             12293..13315
                     /locus_tag="ON488_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCR3232009.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            13332..14261
                     /locus_tag="ON488_001817"
     CDS             13332..14261
                     /locus_tag="ON488_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3232010.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
BASE COUNT         4927 a         2442 c         2885 g         4275 t
ORIGIN      
        1 taagaagatg tttaaatctc gagatggtat cacacttact acagcacata aagttaaagg
       61 aaatgagtat gatactgtta tcgctattaa tcttctaaac gggaaaattc ctcattggaa
      121 tgaaattttt aatgtttctg ataaaggaat tagttcagcg agaaaactac tatacgtaat
      181 ttgttcaaga gcaaaaaata atttatttct tttctcagag gtgggttatt ttacgagtaa
      241 aggagacttg ctttatccca ctcaattatt agataaaata gaatttgatt ataatattta
      301 aaatacctag gtagtcgttg ttttaaatat agtaggaatc ggacgctcag tacggagcgt
      361 ctattttttt acccaatttt gaaaggaagt gaacttatga aaataaaaaa tcaagaatca
      421 aaaggtcgct ctcccccctt taaaaccatc acacaaataa gattcattca aacataaaaa
      481 cagaaaggat aggtaaaaat atggaactta aatatgtcat tcccaatatg gaaaaaacat
      541 ttggacaatt agaatatgct ggtgaaggga acattgaaca acgtcgaata aatggcagac
      601 caaccattct ctctcgtagt tacaatttat actcaacgat tcaacgagca gatgatattg
      661 ttgtcattct tccctccgaa gctggcgaga aacattttga atccgacgaa aaagtcaaac
      721 tcatcaaccc acatattacc gcagaaggtt ataaaattgg caatcgagga tttaccaatt
      781 acattatgca cgcagacgat atggtgaaag cataagaaag gaaaggtgaa aaaatatgag
      841 attagcagaa ggtattgtga ttgaaaaaga ccagacattt ggcacattga aattttccgc
      901 cttgcgtcgt gaggttcgta tccagaatga agatggtacg gtttccgaag aaattaaaga
      961 acgtacctat gacttaaaat caaaaggaca aggacgcatg atacaagtca gtatccccgc
     1021 ttctgttcct ttgaaagaat ttgactacaa cgcagaagtg gaattaatca atcctgtggc
     1081 agataccgta gcgacggcta cttttcgagg ggcagacgtt gattggtacg tgaaagcaga
     1141 cgatcttgta ttaaaaggac agacaaaacc tcatcagaaa tataaaaaag aagcgtccga
     1201 aagtgaaaaa taggtgttgc ttatgacaaa cacaccattg attttgaaag aaattccgaa
     1261 ggatgaagcc atttctttta ttcggcaata ccattattca aagatactcc ctagattgtg
     1321 taaatacttt ctagggattt tttcagaaga aaaattatta ggcgttgtgg aattaggctg
     1381 gggtacgcaa cccctacaaa ccatacgcaa actctttccc gacagttccc ttcaaaccac
     1441 agattattta gaaattggaa agatgtgttt tcttccagaa atgaatcaaa ccaattattt
     1501 tggcagtcaa gctctttcag ctctaattaa gtggttgaaa gaacatacgg actgtcattt
     1561 tttatataca ctggcagatg gaattgaggg aaaatgtggc tatgtctatc aagcgtccaa
     1621 cttcttttac tgcgggtatt tcaagacaag tgtctatcgt gataagcagt catgggaaaa
     1681 gatacaccct cgaagtgctc gccttttatt agaggaaaat gctcgctttg aacaggtaga
     1741 gaaaaagcat tggctttccc aggcattttg cgaatacaaa gggattgaga aaatcaatgg
     1801 acgcatgttt cgctatctct atccgttgac aaaagaagcg aaaaaactgt taggacacac
     1861 tctctatcga cgtcattatt atccgaaaga aaaaaattta cgctttgaaa agcgaatcgc
     1921 ttatcagaaa tatgaagcca tttctcaacc aacttttgat aaacaggctc gtatctacaa
     1981 tacacaatta ttttgatagg tggaaaggag gatttttatg ccattgcttc atgacagagg
     2041 agagcgaatc aaagccaacg ataagcactt ggtctatcat tttgtactaa tttcattgct
     2101 ggtagttttt ctagtcgtcc tactcccttt tcattggaga gcgttacaat cggtgaactg
     2161 gcaagcagtt cagttagata catttttcta tcaacttcat acgccatact tttggagcag
     2221 tattctcact gctctttttg tatgcggact tatcagctgg ctttattatc actatcgtat
     2281 agattctata aaacagttag agcaccgtca aaagttagct cgtatgattt tagaaaatca
     2341 ttggtatgaa gccgaagaaa ctcaatcaga gggattcttt aaagatttac ccagcaagaa
     2401 aaccaaacaa cgaatccgcc attttcctaa aatatattat cgaatgaaag atggactaat
     2461 ccatattcat gtagaaatca ccttagggaa atatcaagat cagcttttgc acctagaaaa
     2521 caaactagaa acaggattgt attgtgaatt agtggaaaaa acgttgaaag attcttatgt
     2581 agagtatgtc ctactttatg atactattgg caatcgaatt ggcattgaag acgtggtagc
     2641 tcaagatgga cgtgtcaaat tgatggaatc ggtctattgg gagttcgatt ctctccctca
     2701 catgttaatt gctgggggca ctggtagtgg aaaatcctat tttattctca cattgattga
     2761 atctctcctg catacaaatg caaagcttta tattcttgac cctaaaaatg ctgatttggc
     2821 agacttaggg gcggtcatga ataatgtcta ttaccgtaaa gaagatatgt tggcatgtat
     2881 caatcaattt tacgaagata tgattgatcg cagtgaaacc atgaaacaac accctaacta
     2941 taaaacagga gaaaattatg cttatcttgg tttgtctgcc aattttctta tttttgatga
     3001 atatgtggca atgatggata tgctaggtcg tgaaagtacc accgttattc ataaactcaa
     3061 acaaattgta atgttaggac gacaagcagg cttcttttta attcttgcct gtcaacgtcc
     3121 agacgcaaaa tattttagtg atgggattcg ggacaacttt aacttccgtg tggctttggg
     3181 tcgtatgtct gaaatgggct ttggtatgat gttcggaagc gatacacaaa aacaattttt
     3241 cttaaaaccc atcaagggaa gaggttacgt ggatacagga aaaagtgtga ttagtgagtt
     3301 ttatacaccc cttgtaccaa aaaggtacga tttcttagga gaaataggaa aagtcattca
     3361 aaaaaagcaa tctgagcctg taccgcacga agtgaaaggt acaggttcag acttgctttg
     3421 attggtgtgg cgttagccac gccaatcctt tagccccctc tatctaacag gggggcacaa
     3481 atacaactga aaacaggcaa ttctcatcaa ccaatgttga tggtacaaag gattgcggaa
     3541 aatatgaaag gtgtaaactc aagggtcata gtttacatct tttttagatt ggaggtttgc
     3601 gaatggaaaa cgaaaaaatt tggattaagg aattgaaaga aaagcgactg gcttatggcg
     3661 tttctcaaaa taaactggcg gttgcttctc atattaccag accttaccta tcggatattg
     3721 aaacaggcaa ggcagtccct actcaacagg tgaaagaaga tttactgaac gctttggaac
     3781 gcttcaatcc cgataaccca ttggagatgt tattcgacta tgtacggatt cgattcccta
     3841 ccaatgatgt ggctcaaatt atcggtgagg ttttacgttt gaatatggat tatatgctac
     3901 acgaagactt tggctattat tcttatcccg aacactatcg tttcggtgat attgttgtcc
     3961 tagtctctca tgatgtaagt aaaggtgttt tattagaact gaaaggaaaa ggctgtcggc
     4021 aatttgaaaa ctttctattg gctcaacatc ggagctggta tgatttcttt caagattgca
     4081 tggaacataa aggtattttc aaacgcttgg atttagctat caacgataaa acagggattt
     4141 tgaatattcc agatttggca aagaaatgta aacaggaaga atgcatttcc gtctttcgaa
     4201 gctttaaaaa ttatcgcagt ggtgaattgg ttcaccgtga tgaaaaacca tacatgggaa
     4261 acacacttta tattggctca ttaaaaagtg aagtctattt ctgtatatat gagaaagatt
     4321 atgagcaata cgtgaaaaat gatgttccct tagaagacgc agaagtaaag aatcggtttg
     4381 aaattcggtt aaaaaatgac cgagccaccc aagccatgaa agatttattg gcacatcaac
     4441 aggcggaaaa aacagccttt gaaattatca atcgctatat ccgctttgca gataaagacg
     4501 acactaaacg tcggagtgat tggaaaacta atgaacgttg ggaatggttt atcggtaaaa
     4561 atcgtggagc attacgccta accacacagc cagagcctta ttcttttgaa cgaacattga
     4621 actggttaca tcatcaagtc gcccctacat taaaaatcgc aagcatttta gatgttctca
     4681 acggtacaac cattatctcc accatgattc aggaagccaa actgacagaa aaacatgaga
     4741 aattaattga acaacaacat ctagccatgg aggatttgat tacatgagcc ttttaacaaa
     4801 agaattaaag aagttagggt ttcagtgtgg cattgagttt caagcgtata tacaaaatac
     4861 agggaaatat acgtctctca ttattgaggg aaaacggcaa gctggtgata ccatctatac
     4921 ctatgatttt tacaaggtga gattttataa taattatacc aatcgagtaa ccgtctatgg
     4981 agagcattta accccttttc aattattaag gcgtgtaaaa agctatatct attatcgaga
     5041 aaaatatctt aaggaaagga ggacaatcac atgaattttg ggcagaattt gtacaactgg
     5101 ttcttggata atgcacagtc attggtattg ttagcgattg ttgtcattgg actgttttta
     5161 ggttttaaac gagaattttc aaaactcatt ggcttcttga ttattgctct aatcgccgtc
     5221 ggacttgtgt tcaatgcagc tggcgtgaaa gatgtgttat taaacttatt taaccgaatc
     5281 attggtgctt aacagatatt tttcatgata aaataggaag tatatatttt gttatgaaag
     5341 gatttatgaa tatgtttaca aatgatcaat ttaaatctct tttaattaaa acattagaaa
     5401 gaaagagctc ttcaaattat tatgaaggag gtaacgagat tgtttctaaa atgaaaatat
     5461 cagaggtaac tttagatgag actgacgatt ttacttatta taaaggatat aaaaagggct
     5521 ggaatacgct ttgcacatat cttaaaataa gagttccttt tgatgattta gacttttttg
     5581 aaagtcataa agatttgatt acccagacag caagctccat atatgataaa caaggtgata
     5641 atgtattagt ggatactatt ttagtaccac ttccagagaa ttacgaagta attaacttta
     5701 gtcagttgaa aattagtgat gtggtttcac aagctattga agacgctgag tcttttatga
     5761 gtaatggtga atatcaacgt gcctttgaca gagttcacac tgcttttcat ggatatttaa
     5821 ttgaaatact aaaaaaatat gaaattacag ttcctagaga cgaaaatcta tctaaattat
     5881 atagtaggat acaacaatta attgaaaaag aaattcaacc tactgaactt gctgatatag
     5941 tgaagacaac gataaggtca tcaaatggaa tgattagctc tcttaatgaa gcaagaaata
     6001 ggcattcact tgcacaccct aatacaaata ttattggaaa gagagaagca aaactaataa
     6061 taggtatttc aagtacagtt acagattata ttagcggata ccttgataag tagcgtcatt
     6121 aactgattgc tacttttttt atgactattt ttataaaaag gatgtgataa gaattggaaa
     6181 tgaaagtcta tgtggcaaat ttaggacggt ataatgaagg tgaattagtc ggagcatggt
     6241 ttactccacc aattgatgag gaagaaatgg cagaaagaat cggtttaaat gaggactacg
     6301 aagaatatgc aatacatgat tttgagcttc cttttgatgt ggacgaatac acgccgatta
     6361 gtgaaatcaa ccgtctatgt gaagccattc aagaaatcga aggtacacct atttataatg
     6421 aactcaaaga aattcaaggc atgtggttta gtagcttgga agaattactg gaaaacaaag
     6481 aggatattca ttgttatagt gattgtgatt cgatggaaga tgtcgcccgt tattacgtgg
     6541 aagaaacagg acagcttggt gaagtccctt ccaatttaca aaattatatt gactaccaat
     6601 ctttgggacg tgatatggaa atagagggta attacctagt tacctctcat ggggtatttg
     6661 aatattgtca gtaagtttaa caatccgtgt tataattaaa ttaataaata gcacggagag
     6721 gtataaatta tggtaaatgt atttgaaaat cttaaactat taaaactaga catgaaagat
     6781 aaaggctggg tgatagattc cttttacttt cgttacaaac agcaaaatta tattgtactt
     6841 gttaagctat ttgaaaaaga ggaaaaagtt ccagaatatg ctctgttaaa actagaattt
     6901 ttaaaggaaa acgatttttc agatatgcta gctgtctatg ctaattcggt aaaattatat
     6961 acagacacga aaacaataag agaatatttt ggtatcgaat acagtagtaa cttgggagat
     7021 gttttatttc aatttagcca aactcttgct cgatttattc cgacagaagt tagtgagaag
     7081 aaaaatgaag accaaaaaga agccatgtgt ttctcattaa gtcaaagtga ttcagaagat
     7141 cccagaaaaa aatattgttt ttcagttaga agaaatcctt taaagggaaa tggtgagctg
     7201 ggaaaacgaa gtccttttaa tgacaataaa acgagattgt atagacccag cttatatgaa
     7261 cgattagggt cagataccaa tttaagtttc agatattcaa tgaatccaga tgatgaagaa
     7321 actgatgaag gtattattgc aaaatggaca aaaaataaaa ttgaatagtt aaagcattga
     7381 aagagcaatc acctattttg attgttcttt ttctattttt acggaaagga cgtgaagaca
     7441 tgaaaaaaat aagaagttac accagtattt ggtcagtaga aaaagtgatt tatgcgatta
     7501 atgatttaca actccctttc ccaattacct ttacgcaaat gacatggttt atcgtttctt
     7561 tgtttgtcgt catactcttt ggcagtttac caccactttc tctgattgac ggagcactac
     7621 tcaaatactt agggattccc attgttctca ctgggttcat gtgccaaaag acctttgacg
     7681 gaaagaaacc ctatggattt ctaaagtcta tcattaccta tgctctacgc cctaaagtaa
     7741 cctacgctgg caaacaaata cgattaaaaa aagaaacaat gaatgaatcg attacgattg
     7801 taaggagtga acaactagat ggcatatccg attaaatata tggaagataa tctcgtattt
     7861 aatcatgatg gcgaagtatt cgcttattat gaattaattc cctataatta cagtttttta
     7921 agttccgatg aaaaaattca agttcatgat aatttctgtc aattgattgc ccaaaatcgt
     7981 gatggcaaga ttcatgctct gcaactagca accgaatcaa gtattcgagc cacacaggaa
     8041 caatcgaaaa aagaaatcac tggacgatta aaagagatag cttacgaaaa aatagatgaa
     8101 cagaccgaag cgttaatttc tatgattggt gacaatcaag tagactatcg cttttttatt
     8161 ggttttaaac tctacctcaa tgaacaggaa gtatccgtaa aaaatgttgg gaaagaaatt
     8221 caaaaagcat ttgcggaatt ctttcatggt gtgaatcaca aattaatggg cgattttgtt
     8281 tctatgccta tggcggaaat cgaacgcttt tctaagatgg aacagttgtt agaaagtaaa
     8341 ttatccagac gctttcagat tcgtaaattg gagaaagatg attttggtta tattattgaa
     8401 catctttacg ggcaaacagg tgtccctttt gatgactacg actaccattt accgaaacga
     8461 tacgaagata aaaaagtgtt ggtaaagaaa tacgatattc tcaaacccac tcgctgttta
     8521 atcgaagaaa atcaacgcta tttacggatt gaacaggaag ataccactac ttatgtggcg
     8581 tattttacaa ttaatagtat tgttggtgaa ttggatttcc ctaatagtga aattttttat
     8641 taccagcaac agcagtttac tttccccgtt gataccagta tgaatgttga aattgtcgcc
     8701 aataaaaaag ccttatctac cgttcgcaat aaaaagaaag aactgaaaga tttagatagc
     8761 cacgcatggg aaagcgacaa cgaaaccagt actaatgtgg tggacgcttt agaatctgtc
     8821 gatgaattag aaagtaattt agaccaaacc aaagaatcta tgtacaaact aagctatgtg
     8881 gtacgggtat cagcaaagaa tttggacgag ctgaaacaac gttgtgatga agtaaaagat
     8941 ttttatgatg atctgtctat caaattagta cgaccttttg gcgatatgct aggcttgcat
     9001 aatgaattta ttccctcaag caagcgatat atcaatgact atattcaata tgtcacgtcg
     9061 gattttttgg ctggtcttgg tttcggtgct acacaaatga ttggtgaaaa ttctggtatt
     9121 tacgtcggtt acaatctcga tacaggcaga aatatttatc tccaacctag ccttgcaagt
     9181 caaggaatta aaggctctgt aacaaatgca ttagcgtccg cttttattgg ttcattaggt
     9241 ggcggaaaat cattctctaa caatatgctg gtctattatt cagtactctt tggcggacag
     9301 gcaaccattg ttgacccaaa agctgaacgt ggtgaatgga aagaaacctt acctgatatt
     9361 gcccatgaaa tcaatattgt taatctcacg agtgagaacg acaataaagg gttacttgac
     9421 ccttatgtga ttttaaaact cccgaaagat tcagaaagcc ttgccattga tattctcacg
     9481 ttcttaacag gtatttccag ccgagatagc gagaagtttc ctgtcctgcg taaagctatt
     9541 cggagtgtaa ctcaaagcaa acaacgaggg ttgttattgg tgattgatga attgcgaaaa
     9601 gaagatacgc ccatcagcaa tagtattgct gaccatatcg aaagctttgt cgattatgat
     9661 tttgcccatc tgttattcag tgatggcagt gtcacccaat ccattagctt ggaaaaacaa
     9721 ctcaatatta ttcaagtggc agatttggtc ttacccgatt ccaatagctc ttttgaagaa
     9781 tacactacca tggaattatt aagtgtggca atgctgattg tcattagtac ctttgcttta
     9841 gactttatcc actctgaccg ttccattttt aaaattgttg accttgatga ggcttggagt
     9901 tttttacaag tggcacaagg aaaagctcta tctatgcgat tggttcgagc aggacgtgcc
     9961 atgaatgcag gggtctattt cgttactcaa aacgcggacg atttactaga tgaaaagatg
    10021 aagaataata ttggcttgaa atttgccttt cgttccactg acctagtgga aatcaaaaag
    10081 accttagaat tttttggtgt ggacaaggaa gatgaaaaca atcagaaacg cttacgtgaa
    10141 ttagaaaatg gacaatgttt agtttcagac atctatggtc gtgtaggggt tatgcagttt
    10201 cacccgattt ttgaagagtt gcttcatgcc tttgatacca gaccgcctgt gcgaaatgag
    10261 gtggaagaat gacacaaaaa caaaagaaat ttcttcacta tagttggata acgctccttt
    10321 gtgtgggcgt tattttactt ttattaggca cgctgggcaa tgcagtacaa gcgacaggct
    10381 tagttgatga aaccattgat acaagcaatg aatactccaa gtatggtttg aatcaatatc
    10441 agcttgatta ttatgtggac aatagctggg gctggcttcc atggaattgg agtgatggca
    10501 taggacaatc ggtgatgtat ggattgtatg ccattactaa ttttatttgg acaatttctc
    10561 tttatctatc gaacgccaca ggttatttgg tgaaagaagc ctatgcctta gatttcatta
    10621 gtcaaacatc ccaagcaatt ggcgaaaaca tgcagacgat tgcaggcatt acaccgaatg
    10681 gcttttccag ttcagggttt tatgtcggtt tcctccttct ttttattctc attgttggaa
    10741 tctatgttgc ctatacagga ttggttaagc gagaaacgac gaaagtgata cgagctgttt
    10801 taaactttgt cgtggtgttt attctatcgg cttcctttat tgcgtatgca cccgattata
    10861 ttgcgaaaat caatgatttt tccaaagatg tcagtaccgc cagtctgaat attgggacaa
    10921 aaattgttct tcctaacacg gatagtcaag ggaaagacag tgtggacatg atacgtgaca
    10981 gcttattctc tgttcaagta aagcaaccat ggctattgct tcaatatggc tccactgatg
    11041 tagaagcgtt aggggaagaa cgtgtggaaa gtttattgtc taccagtcca gatacaaaca
    11101 atggtgaaga tagagaaaat gtagtgattg aagaaattga agatcatgac aatacctatt
    11161 taaccctacc gaagacgatt tccagattag gaacagtctt ctttttgttt gtattcaata
    11221 ttggtatctc gatttttgtt ttccttctaa caggaatcat gattttttcg caagtgctat
    11281 ttattatttt cgctatgttt ttgccaatca gtttcctatt aagtatgttg ccgagttttg
    11341 atggcatggg caggcatgcc attaccaagt tatttaatgt gattatgaca agggctggta
    11401 ttaccttgat tattaccgtt gcctttagta tttccactat gctttattcg ctgtcagcaa
    11461 gttctccctt tttcatgatt atgtttttac aaattgtgac ctttgcaggg atttatttta
    11521 aactgggcga tttaatgagc ctattcactt tacaaagcaa cgactctcaa aacatgggca
    11581 gacaagtgtt tcgcagacct cgtcaaatga tgaatcgaca aaccagaaga tttcaacgca
    11641 gtatgagtaa gatttttcgt ggaaaagcag ggtcaacgaa gcaaaagaca atgacaacaa
    11701 agcagaatca aaccaataaa gctaaccata ctcgtcaaaa tgaacggact acaccaaaga
    11761 aagaaacagc actttccaat gtgaaaaagc aacaaggcgg tatcgggcaa cgattaggtg
    11821 aaaagacagc ccatgtattg gacacgaaaa atcgtctagt caataaaaga aagcaggcaa
    11881 aacaacagat acaggcgaca ccaacccatg tcaaatatgc ccttcatcaa ggaaaagaga
    11941 atgtcactca taatgtaaca gactttaaac aatctatggc agataccaaa gctcaacgca
    12001 aacaacagcg tatgaaccag caggagcaaa aacgaaagaa cattgctcaa aagcgtttgg
    12061 agctggataa agcaaaagaa aaaagacgaa aagaaaaccc atcatctcct gttcagaata
    12121 accagcagca tgttcgcaag cgtcagcaaa ccgtcacgcc tgttttgtca caaaacacta
    12181 aacgtgaaaa tcatcagcga ccattgaaaa aagagcaaaa acaaaagaca ccaccgaagc
    12241 aattcaatca gaggaagcta aataaaagaa cggataagcg aggacaacaa acatgaagct
    12301 aaaaataaca gtgatttgta gtgtggtctt ctctctcttc ttttttctct tattattcct
    12361 agtcattttc tttgcagatg atacggacag tggcgaaaac aacaaggatt cttctattcc
    12421 acaaggcggt gtgaccgttt caccagaagt gttggcacac cgtccgttga ttgaaaaata
    12481 tggtaaggaa tatgggattg aagactatgt ttcttatatc ttagccatta tgcaagtgga
    12541 atcgggcggt acagcagaag atgttatgca aagttccgaa tctttgggtt taccgcccaa
    12601 cagtttgagt accgaagagt ccatcaaaca aggggttaaa tatttcagtg aattattaac
    12661 cagtgcagaa caacaaggag tggatataga ttctgttatc caatcttata attatggcgg
    12721 tggcttttta aattatgtga ggagtcatgg gaaaaaatat acctatgaat tagccgaaca
    12781 gttttctaaa gagaagtcgg gtggtcaaaa agcagactat cccaatccta tagccatacc
    12841 tgtgaatggt ggttggcgat ataactatgg aaatcagttt tatgttcagt tggtttcaca
    12901 atacctaacc gacacttccc caacagaatt tgatgatgaa accgtgcaag tcattatgga
    12961 cgaagccttg aaatacgaag ggtttcccta tgtctttgga ggggcgtcgc ctaccacctc
    13021 ttttgattgt agtggcttaa tacaatgggt gtatgacaaa gctggcattt ctctccctcg
    13081 tgtcgcccaa gatcagtatg acgctacgca agaaatctct atggaagaag cccaagcagg
    13141 cgaccttatc ttctttcatt caacctataa tgcaggcaca tatgtgactc atgtggcgat
    13201 atatttagag ggaaatcgct tttatcatgc aggcgaccca atcggttatg gcgacttaag
    13261 cagtcgttat tggcaagacc atctgattgg ggctagacgt gttattcata actaagaaag
    13321 gaatgaatca aatgattata aaaatcgagc gaaaagaaaa gaaggagaaa ccaaagaaat
    13381 ctaaaaaacc gagcaagcaa agaaaagttc cgatgattaa agttggcacg cataagaaat
    13441 taacctttgt tttatgggtt ttattgattg gtagtgtcgg atttggaatc tataaaaatt
    13501 ttactgccat tgacactcat actgtccgtg aaacagaaat cattaaacag cagattgtcg
    13561 ataccaacca agtagaaagt tttgtgaaat cctttgcgaa agactacttt tcgtggcaac
    13621 aatcccaaga agccattgat aaacgaaatg aaaaattgac ccattatttg acggaagaat
    13681 tgcaggtatt aaatgaagaa atgattcgta aggatattcc tactagttct agtgtgaacg
    13741 atatacaggt gtggcaggtt tctcaagtga atgagaacac ctttgaggta ctgttttctg
    13801 ttgaacaagt tattaccgaa gacaaagaca aggaaactat atcgtctagc tttcatgtgg
    13861 ttgtccatat agatgaatca gataatatgg ttattatcaa aaatccgaca atgagtaaga
    13921 aacctcaaaa atcggactac caacccaaac agctagaaag tgaccataca gtagatacag
    13981 aaacgatgga cgaaatcact agctttttag aaacgttctt ccagctctat cctaccgcca
    14041 cagaaaaaga attgacttac tatgtaagta atcatgtgtt acctatgatt aacaaggaat
    14101 atgttttcga ggaattggtg aatcctatct ttaccagaaa agataaccaa gtaatcgtga
    14161 atgtcgctgt gaaatattta gatcaagaaa caaaggcaac ccaaatctcg caatttgagt
    14221 tgatattaga aaaacaagat aattggaaga ttgtaaaata acaaatattg gtacatgatt
    14281 acagatactt tgtaatcatg tactcttttt gataaaaaat tggagattcc tttacaaata
    14341 tgctcttacg tgctattatt taagtgacta tttaaaagga gttaataaat atgcggcaag
    14401 gtattcttaa ataaactgtc aatttgatag cgggaacaaa taattagatg tcctttttta
    14461 ggagggctta gttttttgta cccagtttaa gaataccttt atcatgtgat tctaaagtat
    14521 ccagagaat
//
LOCUS       DAJSMK010000059        14292 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.062, whole genome shotgun sequence.
ACCESSION   DAJSMK010000059 DAJSMK010000000
VERSION     DAJSMK010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14292
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.062"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(257..598)
                     /locus_tag="ON488_001818"
     CDS             complement(257..598)
                     /locus_tag="ON488_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HCR3232011.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(598..828)
                     /locus_tag="ON488_001819"
     CDS             complement(598..828)
                     /locus_tag="ON488_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCR3232012.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            1124..1462
                     /locus_tag="ON488_001820"
     CDS             1124..1462
                     /locus_tag="ON488_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232013.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPIQIET
                     LVQRISTREDFAIVECEIVAIFVEEGILHDPTHINVDKWQPLIYKLREYTTANQSLSL
                     NFRFQEFKES"
     gene            complement(1667..2242)
                     /locus_tag="ON488_001821"
     CDS             complement(1667..2242)
                     /locus_tag="ON488_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HCR3232014.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPEQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGF
                     YEWNEEKDKFMFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRMPLVL
                     TEEQIEPWVTDVSFARKIITQQMPELVMEKV"
     gene            complement(2607..3188)
                     /locus_tag="ON488_001822"
     CDS             complement(2607..3188)
                     /locus_tag="ON488_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3232015.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASETGKGQFYYYFS
                     SKKEVCLAVIHAHMVVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWIKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(3371..3997)
                     /locus_tag="ON488_001823"
     CDS             complement(3371..3997)
                     /locus_tag="ON488_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCR3232016.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFSLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(4019..5347)
                     /locus_tag="ON488_001824"
     CDS             complement(4019..5347)
                     /locus_tag="ON488_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HCR3232017.1"
                     /translation="MEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTCI
                     NIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARFL
                     SNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPEK
                     LVIIGAGYIGLEFASMFNEYGSKVVVLDAHPEFLPREDEDIAQMILEDMTNAGIEFHL
                     GVSVDQVADQESTAAVTFTENGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDRG
                     AIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVPY
                     SVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETDL
                     ILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(5506..5907)
                     /locus_tag="ON488_001825"
     CDS             complement(5506..5907)
                     /locus_tag="ON488_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HCR3232018.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(5993..6199)
                     /locus_tag="ON488_001826"
     CDS             complement(5993..6199)
                     /locus_tag="ON488_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232019.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(6294..7796)
                     /locus_tag="ON488_001827"
     CDS             complement(6294..7796)
                     /locus_tag="ON488_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HCR3232020.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(7814..8269)
                     /gene="argR"
                     /locus_tag="ON488_001828"
     CDS             complement(7814..8269)
                     /gene="argR"
                     /locus_tag="ON488_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HCR3232021.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(8367..8984)
                     /locus_tag="ON488_001829"
     CDS             complement(8367..8984)
                     /locus_tag="ON488_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HCR3232022.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            9205..10578
                     /locus_tag="ON488_001830"
     CDS             9205..10578
                     /locus_tag="ON488_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3232023.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            10653..11765
                     /locus_tag="ON488_001831"
     CDS             10653..11765
                     /locus_tag="ON488_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HCR3232024.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(11837..13474)
                     /locus_tag="ON488_001832"
     CDS             complement(11837..13474)
                     /locus_tag="ON488_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HCR3232025.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(13642..14250)
                     /locus_tag="ON488_001833"
     CDS             complement(13642..14250)
                     /locus_tag="ON488_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HCR3232026.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
BASE COUNT         3888 a         2969 c         2529 g         4906 t
ORIGIN      
        1 tttctgttaa agtattgtcg cgacttttcg tatacgttaa gatatgtcgt gaaaaaacaa
       61 gttttgtgac acaaaaaaac gaatgacttg aggaaatcac ctcaatcatt cgtttaaaat
      121 gctatatatt ctttagttta agatacggaa attaatccca tcgaccacac tagtagaatg
      181 aacgacattt acttggcctt tttttaattt cgttatgttt agcatataaa aatattatag
      241 agtttactta caatgcttaa aacatatact gtataatctg atcaatttta gccatgtctt
      301 gcaatggtaa gttttctatt tttttgagtt ttcgttcctt aaaatcaaga gattttaatt
      361 gtgtaataat tacttgtcct tttatatcta gctcttcagg taatgagtaa cgtgtcggta
      421 aattctttat agtggaagta attggacata tgaccgaaaa cattgtttta cggttaaatt
      481 cataacgaga gacgactagt cctggtcgtc ttttttgaat ttcttttcct actgagggat
      541 caaaatcaat ccatacaata tcaccttttt taggaatata aattctttct tctgacacta
      601 taaaatttct ctcccttcag gagttaaatc ttcccattcg tctttctcat aatactcggc
      661 ctcttcccca ccactaaatg gatcttcaat ttttggaact aacgtaattg ttccatcatc
      721 agaatacaca acgatatatt cttggttttc tgaaggtttc tttccgttat cagaaggtaa
      781 agttaccact acagaacttc cttgtaatct agattttgta acaagcatta tcatcactcc
      841 cttaataaaa gtatactata taacactaag taacgcaaaa ttcccctttg taaactatct
      901 agaaaattgt tttgtttaaa gtatatctta ttggatataa atagaaataa attgtagcca
      961 gttcattttt tctttaaata aaaaaataat ccaagaaaca ttgaacctat ggatccaaaa
     1021 gctacccaaa tactatagct aactccccgc taccttcaat cttgcagata aaacgctttg
     1081 gaaaaaaatc gagaaaatcg caaagacgac aggccatcct atcatgcctg attataaaca
     1141 aaaagctggc tattcctttt gctctgacaa atttcaattg ggaaagttca cgaaactagc
     1201 aggtgaagaa gtttcaactg ttcggattaa agaatgcccg attcaaatag aaacgttggt
     1261 tcaacgaatt tcaactagag aagactttgc tattgtagaa tgtgagatcg tagctatttt
     1321 tgtagaagaa gggattttac atgatccaac tcatatcaat gtggataaat ggcaacctct
     1381 tatctataaa ctcagagaat atacaactgc caaccagtcg ttaagtttga attttagatt
     1441 ccaagaattc aaagagtcat aatgataaac atcattaggt ataaataaaa aagactcgca
     1501 gaacgagtaa aaaacaaata gaagctatac cttagaaagg tcgactgtga ctctatagat
     1561 gcagtatatg cagcttatga gcatttcttc tgttctcttt gtttttggga tctgtgctga
     1621 agtctttttc gttttttgcc gctctttctt tgaaaaatcg attatgttat accttctcca
     1681 ttactaattc aggcatctgt tgagtaatga tttttcgcgc aaaagaaaca tctgttaccc
     1741 aaggttcgat ttgttcttca gtcaagacaa gcggcattcg gtcatggatt ggtgcgactg
     1801 tgcggttagg ttcagtagtc attatgattg attctgccat tttttcatcc tgatggctac
     1861 gataaaaacc gccaatatac actatttttt ccttatttga aaacataaat ttgtcttttt
     1921 cttcattcca ctcataaaag ccactcattg ggaaaacaca acgattttgc aaaaatggtt
     1981 gatgaaaggt ctttttttct tctactgtct ctgcacgggc attaatcatc aattgtcctt
     2041 ttttaaatcc ggtaaatccc cacttcatga tttccggagt gaggatgttt tcttcctctt
     2101 ttcttaacgt cacaacaaga tttgacggaa aaacttctcc agctgctaat tctgctgcct
     2161 gctccggttg tttcgtctgg gcttctcgat aataattctg aaggagctct gactctagat
     2221 caaaaaaata acgaccacac atcctaatcc ctcccaatct ttttttctat catacactgc
     2281 aacaagaagt ccgtaccaac aaaacgcttt caatttgtgt agaactaaaa aagttgtgac
     2341 aagtgacaaa ctctccagtg aatggtattc tcctgccaac tcctcggtca caagtcacaa
     2401 tattcaacaa acatgagaag ctgctttttg aaattgttcc ttgtgactcg gagtgaaacg
     2461 gcaggcttac gacctctggg taaacggtgt tccagaagta gcttcttcga aaaataagcc
     2521 gaaatttcac aaaaatttga gaagcaattt tcgtaaattc cttcttattt cttgaagctg
     2581 accacttctg tcacaacctc taattattaa agaacctttt gcgaagttaa caatctttct
     2641 ttgatcaatt gaaaattttg tctaagtagt gatagatcct gtgtgacttt caacaataag
     2701 atacttccct ggatttcagc aatcaacgct ttggcttgac ggtctgcttc ttcatcggac
     2761 agtttttctt cagaaagtgc caggatattt tgtttcgtat acttgatcca ttgattgact
     2821 aattctagta gcaacagacg gtattcttca tccactgtac tcaactcaat aatcaaatta
     2881 cctacaggac agccatgata agtgatctgt gtctcatgat cagcaaaaat ccagtccaac
     2941 atttcttcta atgcttcttc tggctgtttt ccagcattta agatgtcttc gaacaattct
     3001 gtctgccaca cgaccatatg cgcatggatc accgctagac aaacttcttt ttttgaagaa
     3061 aagtaataat aaaattgccc tttccccgtc tcagaagctg ctagaatatc tcggattgac
     3121 gtttcatgat agcctttttt ataaataaga tctttggtcg cttccaagat cttttccttt
     3181 gttttcaatg atattctcct ttttcatttc tcatagtcct atattataca ataaattcat
     3241 cattttttct tcttaatcgt ttaaaaaaga ctgtgccaaa ttatctgaca cagccctcac
     3301 tataaaactg ttctcatata gctagatgtt cattgattca agaactgcga ggacaaaagc
     3361 aattcctatc ttatgatagt tgctctaata cttcctctgt tgtcatcact tgatctgcaa
     3421 taaagccaaa gttcgtcaac gctgcatcca ttgcttcttg accaggagca ccaattgcat
     3481 ctgtcgctac cacaacattg aatccactct ctaccaattc acgcatatgg gaatcgctac
     3541 acaagtttcc gttcattcca ccaagaatca ctgtgtcgat tccatttttt ctcaattgga
     3601 gcgccaaatc attgctttct ggtccaaaga ttttatgagg agagctgata atcgtatttt
     3661 catccaaata tggtttcaat tcttcgatga aatcagctcc tgaaccttct tcaactgatt
     3721 catattgact tttcctagca aacatctgtt gctcaagcat catatgttct cctgcaccgc
     3781 caaattgcca tttatggtca tgtgggtaaa aataatgagg agaaataaag agtttgtatc
     3841 ctttttcttt tgcttgtttc accatttcga tcatgttttc gatcgtattg tatttttcta
     3901 agatatcttt tgtcaaacta aagccaccgc ctgctggttt caagaactcg acttgcgggt
     3961 cagtgagaac tactgctgta tttttattat tgaacatggt ggattctcca ttcgttattt
     4021 attttaatac atcatttaaa gcttcactca ttgttggatg agaatagatt tgatctctca
     4081 ataacgtata aggaagtttt ccattcatag ctagcgaaat caagttgatg acttcatgag
     4141 aatcttccgc atagatactt gcccctagaa tcaagtcagt ttcagggtcg actaaaactt
     4201 tgaatacacc tttaggatct tctaatactt gtgctttagg gacaccgctt gtcatatact
     4261 tgaataattt gtaattgacg ccttgtgctt tggcttgttt ttctgttaaa cctacattgg
     4321 ataaagtcgg agtgataaat acactgtaag gcacagcttt ccggttattc gttgttcgtt
     4381 tattctcgcc cttcaactga tccataatga ttcgataatc atctagagag atataagtga
     4441 actgcaatcc gcctttgacg tctccaatcg cccaaatgtt gtctgcatct gtacgaaggt
     4501 attcatccac agcgattgct ccgcgatctg ttagtttaac atctgtattt tctaatccaa
     4561 gtgatgctgt acttggtttt cttccagttg cagccaaaac ttttgacgct tggattgtta
     4621 cttcttggcc attttctgta aaggtgacgg cagctgttga ttcttggtct gctacttgat
     4681 ctacagatac acctagatgg aattcgattc ccgcatttgt catgtcttct aaaatcattt
     4741 gcgcgatatc ttcatcttca cgaggaagaa attcaggatg ggcatcaaga acgacaactt
     4801 tagatccgta ttcattgaac attgatgcaa attccaagcc aatatatcca gccccgatga
     4861 tcactaattt ttccggtaat tgttcctgat ccatcgcttg cgtagaatca atcaagtagc
     4921 gacttgtatt caatcctttg attggtaaaa tgattggttc agaaccagta ttgatgaaaa
     4981 tccgttcgcc ttcaacaatc actttttcac cattattcgt cacttcgatt tgatggttag
     5041 aaagaaaacg tgctgtaccg tccatcactg tcccagttgc ctcatcgctg atcatatgat
     5101 aatttttggc gcgaagcatg cccgtcaatt tttctttccg agcaacagcc tctgtaaagt
     5161 cgattcctct ttctccattg aaaatcaatg atttagaagg aatacagccg atgttgatac
     5221 atgttccgcc atacatacgt gttgactttt caacgactaa aaccgattcg ccttttgaag
     5281 ctaacgcctt cgctaaagtc ttaccgccct ttccaaaacc gatcacaata ttttgatatt
     5341 tttccatcct ttttccctcg cttctttttt tacctaccga ttggtacaaa aatatgataa
     5401 ccgataattg tctattctcc aaatcatctg ctttatttgt caaaaaaaac cagacaaaaa
     5461 gcggtccttt cacgttttta gtctggttcg atttccttta ttcttctaaa caatcgttac
     5521 ttctacatcg atatttcctc tagttgcttt ggagtaaggg cagaattcat gcgcatcttc
     5581 tgcaattttt tgggcttctt cttcgctgat gccatcgata tgcacttcta atactacacc
     5641 gatctgatag ccgccatcat ctaaattata aagagagaca cgtgctttta ctgtggactc
     5701 tgctgtcatt cctgcttctt tgatcatatg ttgtaccgcc ccattgaaac aagaagcata
     5761 acctgctgca aataattgtt ctggatttgt tccttctgca tggattcctg gaggagtgat
     5821 tttcatatgc atcgagccat ttggtgcctc gacttctcca ttgcgcccgc catggttgat
     5881 cattgctgtt tcgtatgctt ttttcattgt actgctcctt tcgattgacc atttgctact
     5941 tggctataat tatagtgtat gacaagtaag gcgctttcta caaaaattct gcttattcga
     6001 ataccagaat gccgtcttct actatttttc caaaaaacaa aaaaatacta ctcgtgaaca
     6061 acagcgtcat atttgttcca aaataaatag caatcttttc tacataatct tttatatgat
     6121 tgattttaag atacatatat accagaaagt tgaccccata aaccaatact gttaaaaaaa
     6181 taaccatatt cgttaccatt ttttcctcct tttgctggtc tccctaccag cactcgattt
     6241 aaccatacca ctttttttgc cgtccaagca actagccttt caaaaagact ggtttattct
     6301 gctgttaatg attcaagatc agaaaaatgt ccgaataatt ttgctaattt tactaacgcc
     6361 aacttgttct ttccgaattc atcattttct atctgtaata ctagtaacgg ctcatgtaag
     6421 cttaaacgga tcaaaaacca gccgtttccg tatggctctt ctagatcata tcgaatacct
     6481 tcttcatttt ccgggtcgaa gttcatccct ttttcttctt ccaacagtcg cttcatttct
     6541 tctaatatct tgtttccttg ttcgcgtggt tcatcgctga acaattttaa tcggatttct
     6601 tgtacttcta cgggctgttt caactctttg atttgttcat ctaatgtgat accttttctt
     6661 tttaattctg gcaaaagcat caggatcttt gcgatgacat atgcaccatc atccagaaaa
     6721 tagttttcct tgaatgcagc gtgtccgctt gtttcgatgg ctagctgtgt atctttccca
     6781 agacggttaa gttctaatgc tttattgatt acatttcgat agccggaaat ataacgaact
     6841 tggatgcctc ctttttcttc aatgaatctt tgtagatgag aagaagtagg ggaattcgtc
     6901 acgattcttg ttcctggatg ctcttttaat acgattgtac ttaatactgc gatcaaatta
     6961 tttcgattga tcactgttcc agaagcactg acaactgcag aacgatccac atctgtatcg
     7021 aaaatgatcc caagatctgc ttcatttgct aaaacagcct gcttgatact ttccatcgct
     7081 tctttattat caggatttgg gatatgatta ggaaatcggc catctggttc caaaaattgg
     7141 gaacctgttg aatccgcacc taagctattc aatacttttt cagcaaagaa tccaccagca
     7201 ccatttccgg catcaacaat gattttccaa ccatttagtg gtttgctttc tagtgttcca
     7261 atcccctttt taatttttgt gactaaatct tgcgcataag gtgtcaaaag gtctgctttt
     7321 tctacgcttc cagtttgttc gctttttatt ttttgctgct gtgataggat aaaagcaata
     7381 tcttcttttt ctgctcctcc ttctgaggta aagaatttta ttccattata ataataggga
     7441 agatggctag cagtcagcat aaccgcagca tcgcacgaga actgttcaaa ttgagtggac
     7501 ataaacatag caggcgtagt agctaattcg aaatcgatga catgtatccc ttgttctttc
     7561 agactttgga tcaacgcctc tttcagtgct ggtccgctta tcctactgtc atgaccaatc
     7621 ccaatcgtcc attttttatt tggatcggtt gatttcttct ttttctttat ccagtttgct
     7681 agtccccagc cgatcttttt taccatgtct gtcgtcaagt ttacttcata tccttcaact
     7741 ggtaatgcga ttcctcgaat atccgatcca ttttgcagcg ctttcatatc tttcatataa
     7801 aagtcctcct catttattcc ctcatttttt ccagcttttc tgcaaatcgc tgtgcttctt
     7861 cttctgagcg gcaaataata atgaatgtat ctacaccggc catcgttccg acaacttcag
     7921 ggtaagccac ttcatctagc caattcgtta ccacatcggc accatttcgt tcagtcaata
     7981 cgataaccat gaactgaaca gactggatac gcaaaacctc gcgtctaatt gctgtacgca
     8041 aacgttcttc atttaaagaa acagatggct ggttaaataa tgtatagcgt actattttgt
     8101 tttcattttg actttttact aacttcattt ctcgaatgtc tcgagaaatc gttgcttgag
     8161 tcacatcggc gcctgcttca tgcagccgcg caagcagctc ttcctgtgtc ccaataggtt
     8221 gttctgtaat gatctggcgg atcagtgctt gtcgctgttt ctttttcata ttagacacct
     8281 ctcaatgttg attatagcaa aagataagta atatttcttc atattttggt attttttact
     8341 tttatttttt gttttcattc aggttgctaa cctttttcta ttttaacacg caaaatcgtc
     8401 ttcatttttt caggtgctga ttttcttgga tcgctgatgt aaatctcttt gtgttcttta
     8461 gaagctcttt catagccttc ttttgcgatg aatgcttcta atttctcaaa cgttgctggt
     8521 tcttcggcat agggcccgac gtgtaagatt tgggcacaaa gaccttcttc catctttttg
     8581 aatactactt gttctttcaa gtcttccgga agtttgctag aacgctgaat ggcttcttgt
     8641 gctatcgctt ctgtaacaaa gtcaggctgt cggatcatca attgataaga aaaatgttct
     8701 tttttcatca ctggttcatg caaatacttt tcttgcagtc cccattgtcc ttccagtgga
     8761 tagacagtat acatctgata atcaggaatc agccaatttt ttttaggcga catgcgtatt
     8821 gcatagctga ctgcatatag acaggctact cttcgtttaa agtcttcctg attcgggtcg
     8881 ccgatccctc tgatgctaaa gaatgatttt ttaggaacct ctagtatttg cgggcttttt
     8941 ttcatactat agctcttgtc tttacgccat tcaatttttt ccatttttct tcctccgcga
     9001 aattccattt agttatttat tatcatacct ctttttgagt gacttggcta atcgtgttga
     9061 cactattttt cagtttgtgc tagaataagt gaagtaaata aatcgtacag ataacacgtt
     9121 tcggcgtgtc gagagagagg cggtttctat ttttataata gaaatcactc tcttttttta
     9181 cgaaattttt tagaggtgat gtaaatgaca aaacaaaaac agctgctttt agtacctgca
     9241 gtaattgcaa cagggatgat gtcttttgcg ggcgtattga tcgagacggc catgaatgta
     9301 actttcccaa ctcttatcag acagtttgat ttaacgactg cacaagtcca atgggtaaca
     9361 acgatttatc ttttgatgat ttcgatcatt gttccgctgt ctacttattt gaatcgcaat
     9421 tttagtctca aaaaactctt tttagcttca aatctgcttt tcttggcagg tataatgatc
     9481 gatttcttct ctcctacctt catggtccta ttgtttggtc gattgctcca aggtgcagcg
     9541 acaggtatcg ctcttccgtt gatgttccat attatcttga catttgcccc cctcaatcga
     9601 cgaggcgcga tgatgggtgt cggtactttg acaacggcca ttgctccagc aattggcccc
     9661 acttatggag gcattatgac ttcacatttt acatggaatc atatcttcct gtttcttgtg
     9721 cccgttttga ttctttcttt gattatcggc tggtttgcta ttcccgagat ggcagtacaa
     9781 aaaagtggtt atttggattg gataagcgtt ttaggaattt gtcttttgtt tagtggaagt
     9841 ctaacatttt tgagtacgtt gggaacagtt tccagctgga ttgctttaat catcggcggt
     9901 attggctggt tcctttttta ctatcgaagt aaaaaagtgg agcatccact gatccgactg
     9961 tctattcttt caaataaaac attccgcttg tttttgattg gcttcttagt ttatcagttt
    10021 ttattacttg gtgtatcttt tgtcttgccg aatttccttc agatcgttca aggaagtagt
    10081 ccttttgtcg ctggattagc gatgcttccc ggcgcagcgg ttggtgcttt gctttctcct
    10141 ttttccggga aaatgctgga tcaatatggt ccgaagaagc caatttttgc tgggctgatt
    10201 ctttctttga ttggttggct agcattattc ctactcatag gacacgcttc agtgggtgta
    10261 ttgattgctt gtcatgtgtt ttatatgatc ggtatcggat tatcttacag caatatgatg
    10321 accaccggaa tgaatgcact gaatgaagaa ctacaaggag acgggaacgc aatgttcaat
    10381 accttgcagc agttttctgg cgctgtggct acttcattag tagcggtcat tatcaattac
    10441 gtccagcatc atacttccca taactatgaa gtgtctacta cattaggatc aaaagcagca
    10501 ttaggcgtct tgttgctgtt gcttctcgta agctttgctc gattcgccta ttatctgttc
    10561 tttgctaaaa aagcgtagat tccatatacg gcaggtgttg catctgccgt ttttttgtgt
    10621 gaaaatggtt gtttgtaaaa ggaggctttt ttatggaaaa aattgccatt atcggtggcg
    10681 ggatcattgg tatgacccta gccagttact tagatacatc aaaattcaat gttgctttat
    10741 ttgatgaagg gacaggacag gcaactaaag ctagcgctgg gattatctcc ccttggttgt
    10801 cgaaacgcag aaacaaacaa tggtatcgtc tggctaaaga cggcgctgct tttttcccta
    10861 aacttataaa agatttccaa cttgatcaaa cgatttacgc acaatcaggg acacttttgc
    10921 ttcgacctga aaaagattta gctgaattgg ctgttcttgc cgagaaacga aaagaagaag
    10981 cgccagaaat tggaaacatc gaatggcttt cacctgaaca gacatctcaa gcacttccgt
    11041 tattgaaacc agcagtttca ctgcgtatca gtggtggtgg tcgtctggat ggaaaagcat
    11101 atttagaaca tcttggtcag cgtttagcac aaaaacaaat ggagcagatc caggcaaaag
    11161 tcactttgca taagaagagc gattcttggc tcatcaaggg accgtttgga gaatacacag
    11221 ctgatcgtgt aattttgaca cctggcccgg cacttaagcc tttattacaa gaattaggct
    11281 atgctgcaga tatacgtccg caaaaagggc agctcttagc atttcagaca tcttataaga
    11341 tgagtcaaga ctggcctgtt gctatgcttg acggagaagc tgatttcatt cctttcatgg
    11401 atggaaagat ccttttaggt gctacccatg aaaacgatca aggctgggat ttggctccta
    11461 ctagcgaagc ttataaggga ttgactaaga gtacagaaca gttcttgact gatccagatc
    11521 agataaaaaa ctggccatac gagttccgtg taggtacccg tgcttatacg tcagattttt
    11581 ccccattttt cggcgtactg ccagatgatc caagcttact ggctgctagc ggtctaggct
    11641 cttctggctt gaccacaggt ccttatatcg gctatctatt agccaacttc ttaaatactg
    11701 gtcattggcc tacggaagat tatcaaaagg acatctccac ctatattacg aaaaatccat
    11761 catagaaaaa cagctttttc aagtaaggat cccgagcgat attgcgcatg gattacttct
    11821 tgaaaaagct gttattttag ttcaatttct gaatcaaatt ctccaaactt tcttttgctt
    11881 catctggcaa gagatctttt cctatctgag cttcaatgaa tcgtaaacga atatcaagtc
    11941 gttgtttcac cagattttta taggacgtat cctcaaaaga aacaggaaaa tctggtatag
    12001 gtaaatagtg gatgtcttca aatggaccaa acgacttgaa ttctgccgtt tgttgcacga
    12061 ttctttcaac gattgacaat gtcgtttcag gtttgatttt tttatcatcg aaatatccag
    12121 tattcaggac atagcaggct gtttgctgtt tcaaaaacaa ctctcgaaaa gcttgatagt
    12181 cttccctaag aggatagaca cggaaaggat tagcaaatgg ttcaatgact agctcatcta
    12241 gctgtctttt tgtagtgata ttttccgcgt ctgatcgttt tgttgctaat gttgcaccaa
    12301 aagacgctgc taaaactggg tcattgatct tgataattgg cggaagcgaa tcatctttca
    12361 tgatccaaaa aacagcatcg atcttttcgc taagatgatc gactcggtcg ggtgtcgcat
    12421 aacgtgattt gactgtccgc ccatttccgt ttcgtatatc tcctgttact aggacttttt
    12481 ctcctttact tgtacatgtc acgcccacat tctgacaagt aaggaaagaa gaaatggccg
    12541 gatcatcaga cggatagtct tgtgttttat caaagtaaga aggttccaag gcagtagcaa
    12601 aaccattttt tcgagaaata acgaaagcat cgtcatgcaa gatcgaaaca gagtgacctt
    12661 ccgtatgttt tgctaaggta atcgttgatt ttccagaacc ggacaaccca aatacagcca
    12721 tcgtataggt ctggtcatta ctagcatatt gtttcatccc accgtggcag gcaataaagc
    12781 cattgcgatt tcccaatgcc caagcaagcg tcaaagtcgc tttttttaat tctccaaagt
    12841 aacgtaatcc tagcacagcc gctgtattat ggagagcatc aaacaaaatg agtccatttg
    12901 gaaatgtttc atgtgtccat tcgggatcac aaaagatata aagatctccc tcatcaaagg
    12961 aaacagactt ttgataagtc tctaagatct tcgaattcgc tggctgaaaa ttcagcaaat
    13021 aagaatacaa attgttctca aatccttctg gaatcagcaa atgactttgc acagaaaatt
    13081 cttcagatag gccaacgatt acttttgtat ggtaaaactg gcgcttgcga ctttgataca
    13141 cagcttctct taaaattttc tcgtatttgc tttgttcctt gtctaagtcc tcaaagatcc
    13201 gccgagcact tgctgttctt cccacaatgc ttccatcatt gaatactagt gtcctaacat
    13261 cagctggtaa atctagttct tcagcatgtg agattgttaa atctgtgatg atcgttcctg
    13321 gactcccttt tgctagttga taagctgtct tcctatcaaa aacttcatga acattattac
    13381 cgtaaaatgt cgtttctaca atcgatcgaa tactggataa cagtggattt ccacttgtga
    13441 tttcgtttaa ttcgagactc tcttttgtac tcatggctcc tcctcattcc ctaaacaaaa
    13501 aaacgttttc tttattatac attattcgag tttttatttg tactgctgcg ctgtgggaag
    13561 caaacgagtt atttttcaca caaaaaaacc gagaacttga ataaacaagt ttctcggttt
    13621 catcattttc cttttatcgg cttagtacca gccgtttgct aaccagaatg ttttagcagc
    13681 atcccatgaa ccataacgag atgttacata ttgttctgct acacgttctt gattggcagc
    13741 tgaatagtcg ccgtttaagt atgaagcatc taattgataa cggccgatgt aacgtccgtt
    13801 agtagctgtg tatgaaccgc ctgattcttt ttgtgcgatc cattcttttg cagagcttga
    13861 agttggcgct gttgcagcag ctggggcagc aggagctact tcaactgttt caacaggtgc
    13921 aacgtatgta tgttcttgcg ttgctgtttc agttgtagat gctgtatttt ctgttgtttt
    13981 gttttctgtt gttgctgaag aatcatttga agttgggatt gttaattgtt caccaacata
    14041 aatgcggttg atgtttgcga tcgaattttt ttcagcaatt gcatcgatca ttgagttgtc
    14101 tcctgcaaat ttttgtgaga tcttagataa tgaatcacct gattttactg tataaacttc
    14161 atcagcgtga gcatttgtag ttcctacaaa cattgcagta gcaccagcag caaaagttgt
    14221 acctaaaaca attttcttaa atgaattcat attaaactcc tttttttctc cgttttttat
    14281 tctttcgacg ct
//
LOCUS       DAJSMK010000060        14204 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.063, whole genome shotgun sequence.
ACCESSION   DAJSMK010000060 DAJSMK010000000
VERSION     DAJSMK010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14204
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.063"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            11..1078
                     /locus_tag="ON488_001834"
     CDS             11..1078
                     /locus_tag="ON488_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HCR3232027.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            1075..1902
                     /locus_tag="ON488_001835"
     CDS             1075..1902
                     /locus_tag="ON488_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HCR3232028.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            1947..2972
                     /locus_tag="ON488_001836"
     CDS             1947..2972
                     /locus_tag="ON488_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR3232029.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            2969..5152
                     /locus_tag="ON488_001837"
     CDS             2969..5152
                     /locus_tag="ON488_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HCR3232030.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            5152..6282
                     /locus_tag="ON488_001838"
     CDS             5152..6282
                     /locus_tag="ON488_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCR3232031.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            6279..6956
                     /gene="pgmB"
                     /locus_tag="ON488_001839"
     CDS             6279..6956
                     /gene="pgmB"
                     /locus_tag="ON488_001839"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HCR3232032.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            7040..7567
                     /gene="msrA"
                     /locus_tag="ON488_001840"
     CDS             7040..7567
                     /gene="msrA"
                     /locus_tag="ON488_001840"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HCR3232033.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(7768..8454)
                     /locus_tag="ON488_001841"
     CDS             complement(7768..8454)
                     /locus_tag="ON488_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HCR3232034.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            8534..10072
                     /locus_tag="ON488_001842"
     CDS             8534..10072
                     /locus_tag="ON488_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HCR3232035.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            10192..10659
                     /locus_tag="ON488_001843"
     CDS             10192..10659
                     /locus_tag="ON488_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HCR3232036.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            11178..11621
                     /gene="rplM"
                     /locus_tag="ON488_001844"
     CDS             11178..11621
                     /gene="rplM"
                     /locus_tag="ON488_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HCR3232037.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            11637..12029
                     /gene="rpsI"
                     /locus_tag="ON488_001845"
     CDS             11637..12029
                     /gene="rpsI"
                     /locus_tag="ON488_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HCR3232038.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(12122..13342)
                     /locus_tag="ON488_001846"
     CDS             complement(12122..13342)
                     /locus_tag="ON488_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3232039.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKTVFEAFQKGLKN"
     gene            complement(13414..13572)
                     /locus_tag="ON488_001847"
     CDS             complement(13414..13572)
                     /locus_tag="ON488_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232040.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
BASE COUNT         4608 a         2617 c         3006 g         3973 t
ORIGIN      
        1 gaaagaaaag atgaaaaaat tagttgcatt agaaccaaga atagccggat tcaaagatta
       61 cgaagaccgt gagatcgaaa agaacgaagt acgtatccga gtaattttcg ctactccaaa
      121 accaggaaca gaaattgtcg actttagagg attaagtcca tttatcgatg aagaattttc
      181 agaagaatgg cgcctattct tgccaagaga agaaggaagc caacgcggtg tggtatttgg
      241 cgaatttcaa ttaggaaata tgattgtcgg tacgatcgaa gaaacgggca gtttggtgac
      301 agagtatcaa aaaggagagt tagtctgcac ttatggaccc attcgtgaaa cgctgattac
      361 aaacggtgtt gataattata aactacgtaa acttgatcgg ttggatcaat ggaaaaatgc
      421 agtatgttac gatcctgctc aattcgcttt aggtggtatc cgggaagcac atgttcgagc
      481 aggtgatgct gtagcaatct tcggtttagg cgctatcggg caaattgcga ttcaattagc
      541 taaaaaagca ggtgctacta ccatcgttgg gatcgatccc atagcgcagc gtagagaatt
      601 agcagaaaaa cacggtgccg attacacgct agatcctatg aaagcagatg tcggttttcg
      661 tctaaaggaa ttgacagata aacgtggagt agattcagtt attgaaacga gtggcagtgc
      721 tgccgcatta caagcttctt taatagggat cggctatggc gggatcattt cttatgttgc
      781 ctttgctaaa ccttttccag ctgggtttaa tcttggtcgc gaagcacatt tcaataatgc
      841 aaaaatcgtc tttgctcgag catctagtga accaaaccca gattacccaa gatggaaccg
      901 taaacgaatc gaggacacat gttgggaatt attgatgaac ggttacttgg attgtgaaga
      961 aatcattgat ccagttgtgc catttgcaga aagcgcagaa gcttacatgc gttatgtaga
     1021 ccagcaccca gaagaaagta tcaaaatggg cgttcaagtc cgaggaggag aacaatgaaa
     1081 ttcggtacgc aagatcaagc atttttccca agagacattt tagaaaaatt tagatttatc
     1141 aaagactgtg gatttgaaga atacgaaatc gacggtaagt tgttaataga aaatatcgac
     1201 acagtcaaac aggcaatcaa agaaacaggg atcccagtag tgacagcttg taacggctac
     1261 gatgggtgga tcggtgactt tatcgaagaa cggcgtctta atggtgtacg tcaaattgct
     1321 gagattttgc gtgcactaag cgaggttgga ggcaaaggaa tcgttatccc agcagcttgg
     1381 ggaatgttca cttatcgatt accgccgatg gtttcacccc gaagcaaaga aggagactat
     1441 aaagcagtca gcgaatcact tcgttattta gataaagtag ccgaagaaac aggtacggtt
     1501 atttatttgg agcctttgaa ccgataccaa gaccatatga tcaatttgtt agcggatgcg
     1561 cgtcattaca ttgactctaa tcaattgaaa catgtgcaga tcatcgctga tttttatcat
     1621 atgaatattg aagaagatga tatttcaaaa gcattgacta cgcaaaaaga gtatgtgggt
     1681 catatccatt tagcagataa tcatcgctac caaccaggat ctggcgcaat tgattttact
     1741 cgccattttc aaacgctact tcaaaatgag tatgaaggtt atatggtata tgaatgtcgt
     1801 ttgcgaggag aaaatgaagt gaaaatttat caggaatcat tgcaatactt gaaaaactgt
     1861 ctggaaacag cgcgtcattt aaatgattta gagaaagaat agagaaagaa taacaataag
     1921 taaataagca aaggagagag aaataaatga agaaagtagc aatcataggc gctggacaag
     1981 tagcagaaaa agtacatgct gcttattatc aaaaaagatc agatgtctta gaattggccg
     2041 ctgtggttga tccagtcagc cagcgagcag aagacttttg ccgacgtaca ggattttctc
     2101 atgcgtatac atcagttaca caaatgctga atgagatttc tcccgatatc gtgagtgtct
     2161 gtacacccaa tcgctttcac ttcgaacatg tattggctgc cctcgaagct aatgcttcag
     2221 tgatgtgcga gaaaccacca gctatgacag ctgatcaagc aagaaagatg gcagagacag
     2281 ccgataaaaa cgggcagatt ttggcttatg gattccagca tcgtttttct gacgaagcaa
     2341 caatgatcaa gaatcatctt gatgttctcg gggatattta ttacgtagaa gcgaatgcgc
     2401 ttcgtcggtc tggtgttcca ggctggggaa cgtttatcga caaagaactt caaggaggcg
     2461 ggcctttgat cgattatggc attcacatgc ttgatacagc gatgtatatt actggatttc
     2521 ctaaagtaaa aagcgttcgg gcgtacagct tccaaaaaat tggtacgaaa aaaaattcag
     2581 ggaaattcgg gaaatgggat ccaagcaaat tcacagtaga agatgcaatt tttggcacac
     2641 tggaattaga aaacggcaag atcatccaac tgaatacttc gtttgctttg aatatcagag
     2701 aagacaaact gaatgtggct ttttgtggcg atcaggcagg tgctaatctg tatccaggcg
     2761 aactattcga agatgtagat ggaaagctgg tttccttaca aaagaccacg ccagttaatg
     2821 acccacatga actaagtatg gctcattttg tgaatcgggc gctcggtgac cagactcaga
     2881 tgattgcaga tggctggcaa ggatatgtca tccagaatct ggtggaaaat ttatatcgtt
     2941 cggcagaaac aggagaagtt attaccttat gaaagtagaa gaaaaacagt ttgatttaga
     3001 gtatatcaat aagtatgcga gtcagatgac cattggaaat ggattttttg gtatcagagg
     3061 aagccaggag gaagactatc ggaatcaagt aaggggaatg tttgcagctg gtgtatataa
     3121 ccgaccttta ggagcagaat cagccgagtt agtgaatctc ccagatgtca tcagatggga
     3181 aataaaaatc gacggtgaac atttttctct tgagacgatg aaagttcttg catacgagcg
     3241 ggcactagat ttagaaatgg gagagcttaa acgctatgcg ctcattgaaa ctgctcaagg
     3301 aaaaaaagtg gaagtcatta cttgtcgtgt tgctgatcaa aataatctcc atcaggcagc
     3361 cctgaaagtg gtcatcaagc cgttgaccga agactgccaa gtagatgtga aaacgggtat
     3421 cgatggacag caaaccaatt ttggtacaca gcagttggtt gaaaaagaac tgcgagtatt
     3481 tggtgacgat ttgatcagtg catcctacca gacaacagaa agtaaaattg atattgggat
     3541 tgcagctaaa ttcaataaag caggtgtatt ccaagcaaaa aatcgccgga tcaccgcttc
     3601 cttttcagaa aagatcagaa aaaatacgtc ctttacgctg gagaagatca tcgtgctctc
     3661 tacctctctt cagcaaacag acccgtttaa gaaaagtatt gcccaagccc agaaaagcgt
     3721 tagttataca gaaattttag agcagtcgat gtcttattgg acagattttt ggcatcagca
     3781 tcggataacg atccaaggcg attcttcttt cgatcagtta gcgatggact tcgctgctta
     3841 ccatttacag attatgactc cccgcaatga tccaagtgtt agtgtagggg cgaagggact
     3901 aactggcgaa ggttataaag ggcatgtttt ctgggatacg gaaattttta tcctgccttt
     3961 ctttttatat cagtttcctg aagtagcaaa gaatttgctg ctgtaccgtt atgatcgatt
     4021 agaaggcgca cggcaaaaag caagagatta tcactatcaa ggtgcacttt tcccatggga
     4081 aagcgcacac actggtcagg aagagacacc caaatttgct gcattgaata tcaaaaccgg
     4141 aacaagacaa gaagttgctt cagctgccgc agaacatcat atcagtgcag accttgctta
     4201 tgccgttcaa gagtatgtcc aagcaacaga ggatcaatcg tttttagaaa caaagggaaa
     4261 aacgctcatt catgaaacag cagctttttg gctgagcaga gctgtaaaag tcgatgatca
     4321 tttagagata cacagagtca ttggtccaga tgaatacaca gaatatatcg acaataatgc
     4381 atatacgaac tatctggcgc attataatgt ggccttagct gttaaatatc aagctggcga
     4441 tccgcttttt ttgaaagaat gtcaaaattt tttagataag ttatatttgc cagtgcctaa
     4501 caaagaacag ctgattccgc aagatgacac gtatctcagt aagccagtta ttgatttgac
     4561 cacttacaaa gaacgtcctg gcagccagtc tattttactt gattatgccc gtagcgaagt
     4621 aaatgaactc caagtcagca agcaagcaga tcttgtcatg ctgttatact tattacctga
     4681 gtatttttct caaccaatcg tttctaagaa tttgcattac tatgaaaaca aaacaatcca
     4741 cgactcatcg ttgagtaaag cgattcacgc catagaggct tgccgtatcc aagaaatgga
     4801 atgggcgtat catttattcc aagaagcgtg cctgattgat ttaggaccag atccgcattc
     4861 atcagatgac ggaattcatg ctgcttcatt aggagcacta tggctagcag ttatatttgg
     4921 tttttcaggt attacagtaa cgaatggaac tctttctatt tctccaagac ttccttcagc
     4981 atgggaaaaa atttcttttc cttttatttg gaaaaatcac aggttgctat ttgttttgac
     5041 aaaaaaacaa atagtaataa aaaaagagac gaaagaaaca ttacctattt ttgtcaatgg
     5101 agaccaatac cagctggaaa aagaactgat cttggaacgg aggggaaaat aatgcgtatt
     5161 ctgattgcgc cagattcttt caaagaaagt ctgacagcct tagaggcagc acaagccatt
     5221 caatcaggtt ttcaagaagt ttttgttcag gctgaatatg atctgctacc tataggcgat
     5281 ggaggagaag gaacggtttc atcattagca gacagtttaa ggttgaagcg gcaaacagca
     5341 gtcgttacta atgcatttgg caaaaacaaa gaaatccagt acgcttcaga cggtcaaact
     5401 gcgatttttg aaatggcaga aatcgtcgga ttgaaagatg tcccactaaa ccaacaacag
     5461 ccacttaggt tatccacgcg aggagtagga gaactgatac gacaattgtt gcaacaaggt
     5521 gttcgacaca tcatcatcgg cgttggcgga agtagtacca acgatggcgg catcggcatg
     5581 gcagaaggtc taggttatgc tttttacgat caagataatc aaaaagtaga agcactggga
     5641 gaaaatctag gtaaaattgc tacagttgat aaaacgaacg tgcctattga gctgattaaa
     5701 gccaaaatca ctgtcattac tgatgttact aatcttttat gcggaaaaga aggcgcttct
     5761 tttgttttcg gaccacaaaa aggcttgaaa gaaaatgaat tagcagtggc tgaccaagcc
     5821 atgcatgatt tttatatgag atttgcccct caagtaatcg aggcatcggg cagtagtgct
     5881 ggtggtggaa tgggtgcagg actgttagca tttgcttcag ggaaaatagt ctctggcatc
     5941 gactacgtat tggatttact ggagttcgat aaacgggtac agcaagcaga cctcgtaatc
     6001 gtaggcgaag gacgtctaga tggacaaagt ctaaaaggaa aagcgccagt tgggattgct
     6061 agaagagtac cagagggcgt tcctgtgata gctatttgcg gaagtgttgg taaaggaagc
     6121 gaaaaagcag cagatgttgg catttcggcc gtttttccga tccttcctgc agctgtgcct
     6181 ttacaagaag ctttacagca agccactgat aatcttcatc gcacagctaa aaacatcgca
     6241 tctttacttc aagtcgttca ttttcaagga ggtaatcgat gaaaatcaaa gcagcactat
     6301 tcgatttaga tggcgttctt gtagacacag ctcgttatca ttacgaagcg tggctggttt
     6361 tagctaacca gctgtccatt ccattcactg agaaagaaaa cgagcaactg aaaggaatat
     6421 ccagaaccga gtcactagag cgattgctgt catttggaaa aatggaacag aaattctcag
     6481 aaaaagagaa atcagccttt gctgagcaaa aaaacaatct atatcttcaa gcgattcaaa
     6541 aaatggatga aacatccgtt ttgcctggtg caatagctgt tcttgagtac ttgaaaaaaa
     6601 caaacatcaa gatcggattg ggatcagcaa gcaaaaatgc acgcctcatt ttagaaaaaa
     6661 cgaatttgac aagttatttt gatgtcctta ttgacggcac gcaagtatca aaagcaaaac
     6721 ctgatccaga agtttttctc aaaggagcac agcaattgaa tgtaccgcca aatgcatgct
     6781 tggtcattga agattcagaa gctggttgtc aagcagcttt ggctggtaac atgcatgtat
     6841 tgggaatagg tgaaaacata aatcttcctt ctgctgaata tgtgattcct gatttaaccg
     6901 tttttgatca agtacgttcg ttttggcatt tatcagaagc cgtatcacgt atataatagt
     6961 ttccgttttt tctgtcacaa gcaaaacgtt atcctccttt tggaaatcaa ggtatgatga
     7021 gaaaaaaggg ggattttata tgacaaaaaa agcagttttc gcaggcggat gcttttggtg
     7081 tatggtcaaa ccatttgaag agcagccagg gatcatttct gtgacatccg gttatactgg
     7141 cgggcatgta ccaaatccaa cttatgaaca agtaacaaca ggcacaacag ggcatacaga
     7201 agcagtagag atcgaatatg atccagaagt tatttcttat gatcagttgg tggaaatcta
     7261 ttggcagcaa accgatccga ctgacgcatt aggacagttc gctgatcgcg gtgattctta
     7321 tcgtccagtg atctactata atgatgaaga agaacgaaat attgcagagc gttcaaaaca
     7381 agcattgcaa gacagcgggc gattcgataa gccaatcgtg acaaaaatcg aaccaagaag
     7441 cgaattttat cctgcagaag attaccatca ggattattac aagaaaaaca agctccatta
     7501 caatctttat cgagaaggtt ctggacgtgc aggtttcctt cgtcgacatt ggggcgtcaa
     7561 gaaataagaa gccgaaaaag ctacttatgg aacaccgtat atcagaggtt gtaaaaccag
     7621 cattttgagc taatactgag ggtcagctga ttgaacacca tttagtggag aggttgtgaa
     7681 cctgtcgcct agctccaagt cacaaggatt tggtaagaga acactatata tcagaggttg
     7741 tgacaagtcg tttgtcacaa ccttttttca atacctaaga tgaaggacaa tcagcaacgc
     7801 actgctcaaa aaaggaatga aaggcagctt ttccaacttt tttttatgac agataaagta
     7861 aacagaaaaa acggatattc caaacagact agcaagaaac aagatctgaa gcaactcttc
     7921 tagagacaag ccaccactcc aagaaagcat caacagagta tcgccagctc cgagatagga
     7981 ttgaccatag cgaaggcaca caccgcctac gataaacgtt aacagcacac tttgccattg
     8041 gaagacgccg gcctgcaacc aaaaaatcca taaaattgcc caagaacaga atagcgtgtg
     8101 agaatggacc atgaagtaaa ataaatccat caacgaaaat agcaaagccg aaagcatcca
     8161 tatgaacgtc gaaaaatttc ttgcggaaga aaaagtaaag aaccaggcaa aaagaccacc
     8221 acataaggct tctgccaaca aatagtagaa gggcaaccga cacctgcaat agcggcagcg
     8281 aaatcgttgg acgatgatcg agagaatcgg aatcaattca taccaagaaa gcgaacgaca
     8341 gcatttgaca caatgagatc taggataaat aatagagtga cctaacggaa tccgctgggc
     8401 ggttaaacat aaaaatgatc cgatacagca accaatgata aaataaagta acacgccatc
     8461 tccccctttt caaaaccaag atacgcaagc ttaaactaaa tttttgtaca tacataaaat
     8521 ttgaggtgaa aaaatgaacg tttcaatcgg attagatatc ggaaccacac aaaccaaagc
     8581 agttgctttc acagatgaag cccaagaagc agcatccgct tattttcgct accctttgat
     8641 ccaagaaaca caagggatgg cagaacaaga tcaggaattg atctttcaag gtgtctgcac
     8701 cgttataaaa gaagtaatta aacagttgcc ttcagacaca atcattcaat ttgtctcctt
     8761 ctcctctgcg atgcatggcc tgatattgtt ggatgaagag aaaacaccgt tatctcgaat
     8821 gatcacttgg gcagataacc gagcagcgga cgaagcagaa aaactgaaat ataccgtgct
     8881 tggcaaagaa ttttatcggc agactgggac gccgattcat ccaatgacac cattgaacaa
     8941 aatcaagtgg ctgcaaaaca gccaacctga attattcaaa aaaactgctt attttgtcgg
     9001 tatcaaagac tatatctttt atagattgtt tggcgaactg atcagcgact acggaacagc
     9061 ttcaggaact ggatattttg atatccatga attccaatgg gcagaagaag tgcttgacta
     9121 cttgaacatt cgaatagagc aattgccgca agtctttcct tccacctatc aagtaacagg
     9181 tctaccatca aaaacagcag cagaactagg tttgccaaat gatatatcat ttgttttggg
     9241 aggggcagac gggccgcttt ctaatctagg gttaggtgct tttggtgata cgatcgccgc
     9301 tttgaccgta ggaacgagcg gagcacttcg ttttattact actcagcctc agttccatcc
     9361 agaaatggag acgttttgtt atgttctgga tcagaaacat tgggtagtgg gaggagcgac
     9421 tagcaatggt gctggcatct ttgattgggc agggcataca tttttacagg aagtcgttca
     9481 atctgctaaa gaaaaaggag aaaatccata tgatgcactg ctttcggcta tcgcttttgt
     9541 gccagcgggt gccaatggtc tgatttttca tccctattta cttggtgagc gagcaccgct
     9601 ttgggacgca gatgcgtttg gcagttttat cggtttacag cggcaacata cagaaaaaga
     9661 aatgatgaag gcgattctag aagggatctg tctcaacctt tatcggattt taaaaggagt
     9721 ttgccaggaa aatcagctca cagagatccg tgctacaggc gggtttgctc aatctccgat
     9781 ttttcgtcag atgatggctg atgtactggg ttacccgctt gttttcccta ctgtcacaga
     9841 agcatccgca ttaggagctg tgattttagg ctggagaagc atcggaaaga tccaaagtat
     9901 cagtgaagca caggaattga tagaattgaa agagcaagtt ggagtacaag aaactgatca
     9961 taaaaaatat cagaaaatct atccattatt tgtttcgaca caaaagcatt tagcacagac
    10021 ttatcagcaa tttgctcaac tgcgagaaga attagctgat tctgaaaaat gattggcttt
    10081 acggataaaa aagcgaactg aaaatcgttc tcaggtaaat gattttgttg tacttttcat
    10141 tgaaagtcta ctattatttt aagtgtaaga aaatgttagg aggcaagaaa gatgaaattc
    10201 caacaaacca aagaagtatt aaatcaatta gttgcagatc taagccaaat gtctgttgtt
    10261 gttcaccaaa cacattggta catgagagga ccaggtttcc ttacattgca cccaatgatg
    10321 gatgagttca tggatgattt gaacgctcag ttagatgaag tatccgaacg cttgatcaca
    10381 ttagacggtt caccttattc tacattgcgt gaatttgcag ataacacaaa aatccctgat
    10441 gaaattggcc gctgggatcg tactattcca gaacgtttgg aaacacttgt tgcaggctat
    10501 cgttatctag cagatcttta ccaaaaagga atcgaagttt ctggagaaga aggcgacgat
    10561 ccaacacaag atatctttat cgaattcaaa acagccacag aaaaacgtat ctggatgatc
    10621 caagctcatt tgggcaaagc gccagagatc gacgcgtaaa aactgttgtt gaacttgacc
    10681 gaaaaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa acgtcaaaat
    10741 agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt
    10801 ttaccaagag gttgtaagcc tgccgttcag ctccgagtca caagaaacaa ttttaaaaaa
    10861 cagcttctta tgttttatgg atattgtgac ttgtgaccga ggagttggca ggagaacacc
    10921 gtttattcaa aataaggggt tgtgacaaga cttttgtcac agcctctttt tgtttttcat
    10981 tttgacagga aacgaccctt ttatataaaa gaaagaaaag aagtaaagtt tcatataaat
    11041 ttttcaatca agcagaaaaa cgttgacatt gactagatta gcgggtaata tgttaaatgg
    11101 tattgtttgc cccacaaaga gccccggaaa ctcgaagtgt atgtcaaaca tcagaactta
    11161 aattggagga aaataacgtg cgtacaacat atatggccaa accaggcgaa gtagaacgta
    11221 aatggtatgt agtagacgca actgatgttc cattgggacg tctttcaaca gttgttgcat
    11281 ctgtactacg tggtaaaaat aaaccaactt tcacacctca tttggatact ggcgatttcg
    11341 tcatcgtcat caatgcagac aaagtgaaat taacaggtaa aaaagcgact gacaaaattt
    11401 attaccgtca cagcaactac ccaggaggat tgaaatcaat cactgctggc gaattgcgtg
    11461 ctaaaaattc tcgtcgtttg atcgaaactt ctgtaaaagg tatgcttcct aaaaacactt
    11521 taggccgcaa acaatttaca aaattgaacg tatacggtgg agcagaacat ccacatgcag
    11581 cacaacaacc agaagtttta gacatcacaa acttaatcta ataggaggga atttcattgg
    11641 cacaagttca atatatcggc acaggccgtc gtaaaaacgc agttgctcgc gtacgtctag
    11701 taccaggaac tggcaaaatt actgtaaata aaaaagatgt tgaagaatac attccacatg
    11761 ctgacttgcg tgaagtaatc aatcaacctt tcgctgttac tgaaacaaaa ggcgcatatg
    11821 acgtatttgt taacgtaaac ggcggaggat acgctggaca atcaggagct atccgtcatg
    11881 gtatcgctcg tgcattgcta gaagttgatc ctgacttccg tttagctctt aaacgtgctg
    11941 gcttacttac tcgtgacgca cgtatggtcg aacgtaaaaa accaggtctt aaaaaagctc
    12001 gtaaagcttc acagttttca aaacgttaat attctttgta tatcaatgtt tcaagacact
    12061 tttcaattat ttggaaagtg tcttttttta gtttaagaac acattcgaga acacattcat
    12121 cctagttctt taatcctttt tgaaatgctt cgaaaacagt cttatcaact acatctggtg
    12181 tgtttacgta tatctttgta gtagaaatat ctgagtgtgt taaagcatta gatatttgat
    12241 tcatatttgc tccgccttgt ctagctatag ttgcataggt atgacgaagc ttatgtggag
    12301 ataaatgagc caattcagga tgtcgtcttt taattgaatt gattcgatag tttaggtaat
    12361 cagcgtgaac agggcaattt acttctccgg atggtttagt ataggtaaag agatactgat
    12421 ctggtgtttg attaattttt aatctcaaca attgctcagc ttgcactgat ttccatttgc
    12481 ttagtaatgc cattacaatt tcgggtactt gaattacggt atcctttcga ccttttgtaa
    12541 atttcttttt ttgatattta tccaaagcat gtttaaggcg aaccgtttgt ttctcaaagt
    12601 cgatatattt ccattgcaaa gcatacgtct cactttttct atcaccaaga tatagggtaa
    12661 gcatgaaaag agtatagtca tgaagagtaa gcaagtgatt attcaagtca gtgtttactg
    12721 cttctatcca agcaataagc tcttctgacg ataatgcttg attaccttcc cgtatccttc
    12781 tttcttctaa agcaattttt ttaggtgcag tgatacattg aataattttg gtagttcggt
    12841 taaattcaat ataatttagt atttctgcaa tatcaaacat agaacggaca tatcctttga
    12901 taatttttat atttgcgtat tctttcgatt tttttgttaa ttcatctgat attatctcag
    12961 tatttgaatt tagatagttc attgcatact caccaaacat tggaaggatg tgcaatcgga
    13021 atatatcttt agtattacta attgttacgt aacttggagc tctttttgat ctagtagtct
    13081 gacctagttc atatctagga agccattttg attcatagaa ttccttaaat tttatttttc
    13141 cttttaattc tagtgaattt gcattctcct ctcttaaaac tgtttcaatt ttccttttca
    13201 ttgcattttc ggctttaata gccaattgcc tagttggaaa tactttttga tacttttctg
    13261 atgtaattcc agtgatttct ctgaattttt ttggatacct cagattagtt ttatatttcc
    13321 catttgaaag ttttgtaggc aaaattcctc actcccttaa aaagtaaggc agtatatttc
    13381 gctattctta gtatatgcgg cgagaagaaa ttttcaaatt gttttaaatg tattcataaa
    13441 atctttgata tcctctatgt caaagcgaac tataccgtca attctgatta ctggaaaatt
    13501 atatatacga atccacttat ctaaagtatt attatcaatt cctagaaact cacaggtttg
    13561 ttttttattc aagtagactc tcaattttat aaaatcatct cctaaaaaag attagaattt
    13621 ttgaattgct ttgggtaagc acataggaat ttcacctctc cccagtttac ggcgagcctt
    13681 acggaagtat cattatttgc tgctattgtc atggcatttt gttttcccag aacaaaaaga
    13741 aatctctaag tatttgtcgc taatcaggtc atggcgtact tgagtttcta gctcgaatag
    13801 cagggatcgt tattcaaaaa ttgtatttaa ttgtcaatga tcaaaaatag gttttttcct
    13861 attcactatt aataacgata aacatgtata aaaagacaca ctacgaaaaa agttaaatgg
    13921 agtttactga ttttcatatt tgtatatgga acagacatag tcttgaataa tttttataaa
    13981 tgttttgatg cttatcaact tattcaaccc gctatccact ttaagtataa tttttccata
    14041 cgccaataaa gtagttttag gagcatgttc tcatttgaga acgctccttt tttatatatt
    14101 ttgaaagcta cttactatac gcgtagtttc aaatagtttt gtcattctaa tcttcagcaa
    14161 cagaaaaaaa tctaaattat aaaatttagg gttgactaaa atat
//
LOCUS       DAJSMK010000061        14119 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.064, whole genome shotgun sequence.
ACCESSION   DAJSMK010000061 DAJSMK010000000
VERSION     DAJSMK010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.064"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..556)
                     /locus_tag="ON488_001848"
     CDS             complement(<1..556)
                     /locus_tag="ON488_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HCR3232041.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="ON488_001849"
     CDS             complement(572..1051)
                     /locus_tag="ON488_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HCR3232042.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="ON488_001850"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="ON488_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="ON488_001851"
     CDS             complement(2098..3204)
                     /locus_tag="ON488_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HCR3232043.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ON488_001852"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="ON488_001852"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HCR3232044.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ON488_001853"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="ON488_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HCR3232045.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ON488_001854"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="ON488_001854"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HCR3232046.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="ON488_001855"
     CDS             8175..8873
                     /locus_tag="ON488_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HCR3232047.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="ON488_001856"
     CDS             complement(9041..11680)
                     /locus_tag="ON488_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HCR3232048.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ON488_001857"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="ON488_001857"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HCR3232049.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14119
                     /locus_tag="ON488_001858"
     CDS             13523..>14119
                     /locus_tag="ON488_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3232050.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2544 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagcg
//
LOCUS       DAJSMK010000062        13911 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.065, whole genome shotgun sequence.
ACCESSION   DAJSMK010000062 DAJSMK010000000
VERSION     DAJSMK010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13911)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13911)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13911
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.065"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(58..351)
                     /locus_tag="ON488_001859"
     CDS             complement(58..351)
                     /locus_tag="ON488_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HCR3232051.1"
                     /translation="MELTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEMDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(379..1044)
                     /locus_tag="ON488_001860"
     CDS             complement(379..1044)
                     /locus_tag="ON488_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HCR3232052.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1184..1816)
                     /locus_tag="ON488_001861"
     CDS             complement(1184..1816)
                     /locus_tag="ON488_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3232053.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     ALRPDVILMDLVMEEMDGIESTKAILKDCPKAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNDPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1823..2890)
                     /locus_tag="ON488_001862"
     CDS             complement(1823..2890)
                     /locus_tag="ON488_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCR3232054.1"
                     /translation="MMGRISKAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLMAISLGVGLIVFLLLSLIQKAKYGKIEEKLRALSSGNYESKLLHQP
                     IPSASDDLYIKDIDMEIAKIKEKMIEVSSELQIMTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLTSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2887..3618)
                     /locus_tag="ON488_001863"
     CDS             complement(2887..3618)
                     /locus_tag="ON488_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HCR3232055.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKYPRTKFQNFQLILGSLVIFFSLVNSPALWMMVVLAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMVQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAIISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKICSS
                     DYDENPRRLKIITNTLVGDVEVIRI"
     gene            complement(3786..4265)
                     /gene="greA"
                     /locus_tag="ON488_001864"
     CDS             complement(3786..4265)
                     /gene="greA"
                     /locus_tag="ON488_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HCR3232056.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGD
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="ON488_001865"
     CDS             complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="ON488_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HCR3232057.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPNGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELYQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEKAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVQKYVNNS"
     gene            5741..6901
                     /locus_tag="ON488_001866"
     CDS             5741..6901
                     /locus_tag="ON488_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HCR3232058.1"
                     /translation="MAKGKHQKKQQISLSFLAVLLLAVSFFSTGIITGWQLTKQPQPQ
                     IYKTEPAQLASNLTSNEQMLASKIDQLLQKSDYIGSIYVRKNNRVILEKGYGYANLRI
                     KESNSPSLYYQIGSIQKAMTALLILKQIQSGKITFDTKLSEFYPQIPGSQQISIKNML
                     YMRSGLHRTASPKKPMSDSEIIQFALHHLKFTGYDTYHYEPLNYTLLTGVLIKLMNQP
                     YETLLKKEIIRPLHLEHTDFYENVKNSPQHAVSYQMSATDDYSKALVEPETDIRNELG
                     TGNISMSVYDLNKFFTSVLSGDIIPKELLFSLWQNNGDKHPYSGGVYSGNDYILAQGN
                     INRFHAVAAMKKDTKDAIVMESNIQSDKNIKLPATDLRNQIYELMEGVNLKS"
     gene            complement(6941..7888)
                     /locus_tag="ON488_001867"
     CDS             complement(6941..7888)
                     /locus_tag="ON488_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HCR3232059.1"
                     /translation="MDTILITGGAGFIGSTLANYLGKENKIVVVDDLSMGKKENLDME
                     KQVTFIEGDVSDPQLMERIMKQYQFAYIFHLAAVASVADSVERPLETHRVNFDSALLL
                     LELVRKYQSGLKRLVFSSSAAVYGDEPTLPKKEESVIRPLTPYAIDKFASEQYVLDYC
                     HLYDVPTSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQLAGEKTEFTLFGDGSQSR
                     DFVYIEDVIQALLLVAKEEKALGQQFNVGTGKSTTLLELIHSIDQILGTELALKYEAE
                     RSGDIRDSLADISKIRSLGYQPKFDILNGMERYLKTEID"
     gene            complement(8021..9412)
                     /locus_tag="ON488_001868"
     CDS             complement(8021..9412)
                     /locus_tag="ON488_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HCR3232060.1"
                     /translation="MLNEKFLKYVKGWYFIYFGFILMLRAIGPYLLLPTRYDTLLFWP
                     AGIAGVVLIIIDAIIAFREKNLKKYDWLLIAFIGAMLVSSLMNLKYGYSENIKLIMWQ
                     LIFFFMIYQFGKDYSSNFFFKVFTWILSLVWFLANLVSLYWFVIQYGIKIPIKYKYYP
                     VRLGWLGNRLFGVYTDPNFGAVISLIVIIIAIYYLVTYKHLNLLFKIFFAINIFIQFS
                     FIALSGSRTTLVCLLIATFVFSFFTSYSSRFLKTNTLKRWLTALVVGLLSIIAMYYVT
                     DITAQAWAHVPHITEIKKDISDSSGTTSSNKVDLKRPDTDGGDVSNLRFGLWKSAIEI
                     FKSKPISGGSPGYYIEYAHDKLPYTLMGKDTLTAHNFIFLVMAATGGLGLLTLLTFLF
                     IQCFKTLRYCFTQPNLVKDKHFFAILMILTIAVSALFITELILVSTIGSFIFWGYLGS
                     IQKTISKEEGVTN"
     gene            9538..9948
                     /gene="tagD"
                     /locus_tag="ON488_001869"
     CDS             9538..9948
                     /gene="tagD"
                     /locus_tag="ON488_001869"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HCR3232061.1"
                     /translation="MKRVITYGTFDLLHYGHINLLKRAKQYGDYLIVALSTDEFNWNA
                     KQKKCYFSYEKRKQLLEAIRYVDLVIPEENWEQKVKDIKEYHADYFVMGDDWAGQFDE
                     LEQLTDAQVIYLPRTPEISTTQIKNELNSLNSDK"
     gene            10128..11417
                     /locus_tag="ON488_001870"
                     /pseudo
     CDS             10128..11417
                     /locus_tag="ON488_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(11484..12911)
                     /locus_tag="ON488_001871"
     CDS             complement(11484..12911)
                     /locus_tag="ON488_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HCR3232062.1"
                     /translation="MKKTVKDIFYNAIYQVFLIVLPLLTIPILSRRIGSTGLGIYGYV
                     FSISQFLMTVIAVGMNPFRIRNIAKSRKDKKALSLQFWNIYFIQFLIGLSVSFLYIAY
                     IYFFDVKYKNLYLIQLIFIVGLTLDISWFFQGIEEFSKVVIRNTVIKLSSVLLIIIFV
                     STKDDLWIYVFITSITNFLGSLVFWLSIHGKVGKPIFNSNVFKQLWKPAFIILTPQLF
                     MQVYTTLDKTIVGYFVDPTELSYYDQSQKIARIILAVLTSITIVMLPKISKAQAEGKS
                     ENILVYTKKSFDYTIIIALILFSVVFINTKEFVPWFFGENFKPMTINMLISCLIIVVS
                     PIGGVFANQFAIAIEKDKEYAYPMIIGAIVSIIGNVAFVPTYGAVAATIVLVVVELLV
                     FFFRVFFVRKEIKISYFFGKNVILFFIVNLTLTTWAYYFLPQLFSSSFLDMAIKSIMI
                     FIIYLPFVYFLFPDIRNEIRKITRK"
     gene            complement(12908..>13911)
                     /locus_tag="ON488_001872"
     CDS             complement(12908..>13911)
                     /locus_tag="ON488_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HCR3232063.1"
                     /translation="IHEKKLNYRIIWLIKKEAIITDLPDYIKRIDSDSFLAAFYLYTA
                     KYWIDDSRKTIKYAKRKKQLYFQTWHGTPLKKIEFDAKDKLPKRYLSYAKKDSESITY
                     LLSGNRYSSKKYVSAFNIVPSKILEVGTPRNDELASSKEQVFDLKKKQINVLFAPTFR
                     NNIEDNGITQLEWLGVDNLREFFKKQQQELNFMTKFHPNVHSKLATDSKSIEYMKKHQ
                     ITLINDGIPLEMLFEEIDVLITDYSSIFFDFALTKKPIILFNYDEKEYSLERGFYIQL
                     SELPIISVQDSYGLVDVFKNQQEKLLKSSQELLDYIGNYETGASTEKVLELIERDIK"
BASE COUNT         4548 a         2664 c         2066 g         4633 t
ORIGIN      
        1 caatattttc aaaagaaaaa agagaaggtg acaaaaattg tgtcaccctc tcttttttta
       61 ttgtttttta aagtgatagg ttggctcctc caggttggga tcataatcaa caagtaaatc
      121 atatccttta aagaaccatt catctgcttc ctcgataaaa aaaagtgtcc catccatttc
      181 cactttcttt acaggatgtt ctggctgttc aactgacatt ccaatcgaaa aaccatcatg
      241 aacctctgtt ttgccgtaga cttttccaaa aaaacgtatt ccgtaagttt ctggcagatc
      301 aatttctgag tcaaaccact tttgtgcttt tggcgttacc gttaattcca tcccaacaac
      361 ctactttctc ttttctttct attgattcat cttatcgtct agaatatcca catcgcctgt
      421 ctctccaatc accagtagat tatcattttc gcgaacatat tcatctgctg caggagaagc
      481 gataaccgtt tgatctactc ttcgtatggc gactactgtt aagtcaaaac gttgcctgaa
      541 atttaattca gctaatgttt tgttgaaaaa tttaggattg gagactcgga tttctgctaa
      601 agaatattta tctgacagct ctaagtagtc tagaatattc tttgatacta agttatgtgc
      661 aatccgtatc cccatgtctc gctcagggtg tacgacacga tctgctccga tcttctctag
      721 tacacgggca tggtactcat tttgggcttt tgctaaaata ttcggtacgc ccatttcctt
      781 taccatcaga gtaactaaga tactggcttg gatatcttct ccaatagcga caattacatg
      841 atcgaaattt cttataccta atgaacgaag tgtcatctca tcctgtgcat ttgccacaac
      901 agcatgagtg gctatattca tatattcatt gactcgatct tcattactgt caatagccag
      961 tacttcttgt ccagcttcga tcagtgtacg gcagatgctt ccgccaaatc gtccaaggcc
     1021 tacaattgca aaattttgtt tcaccatttt cctcctttag tatcttcttt tctcagtata
     1081 acaaagcctt tccaaaaaca aaagcaagca tcattattgt aaaaaagcca agaaaaataa
     1141 tagttatttt ctcagctttt gattatcctc tttatcatcg tttttatttc accaaaccat
     1201 gtttaaacgc atagatagct gcttgagttc ggtcttctac ctctaactta gctaatatat
     1261 tcgacacatg cgttttaact gttttcagtg tgataaacaa ttcatccgcg atttcctgat
     1321 tacttttccc ttcagaaatc agcatcaaaa tttcattttc tcgattcgtt aattcttcat
     1381 gcaatactgg atcatttcgc cgactcattt tttccatcat ttttgttgtc acttcaggtt
     1441 ccaatactcg ctcgccgcgt tgcgtagccc ttatagcatc agctatttca tgtgcggtag
     1501 acgtcttcaa caaatatcct gctgctcctg cttcaattgc aggataaact ttttcatcat
     1561 caataaaact tgtgacgata atgattttgg cttttggaca atcttttaag attgcttttg
     1621 ttgattcgat gccatccatt tcttccatga ctagatccat taaaatgaca tctggtcgaa
     1681 gtgccatcgc cttttcatag ccttgacgtc cattttcagc ttctccaatc acttcaatgt
     1741 cttcttggat agataaataa gaagagacgc ctaagcgtac catttcatgg tcatctacta
     1801 ataaaacttt tatcatcttt atctatgcct ccttcatcaa agggaccttg atctccacgc
     1861 tcgtaccttg ccctttaaaa ctaatgattt ttactgttcc accaatacca gctactcgtt
     1921 ctttgatatt gttcaatcca taacttcccg ttttggtttc attcatatta aatcctgtcc
     1981 cgtcgtcaat gatacgtaat aaaagattgt tatctatttt atgcaaatag acttctaatt
     2041 cattagcctt agcatgtctt aatgtgtttg ataacaattc ttgaacgatt cggaacaagt
     2101 gatcctcaat ggaactagtt aattttacat cttctacatc ccattttagc gaaatctgga
     2161 ttttattctg caattccttc aataactgct caatgccttg ttttaaactt ttttcttcta
     2221 aattgactgg acgcagatga agaagcagcg cacgcatctc agactgggaa gcgttgatga
     2281 tctctgccac cattttcaac tgcttacgga acatttctgg tgtctcactt ttttctgctt
     2341 gctccgtcaa tgccgacatc atcatcatcg ctgcaaataa ttgctgtgaa actgaatcat
     2401 gaagctcacg agctaatcga tgcctttcta attctaaaat ctcttctttg gtttgtccat
     2461 ctacatattg aggacggcta gtcataatct gtaattcact ggatacttcg atcatttttt
     2521 cttttatttt agcaatttcc atatcaatat ctttgatgta cagatcatcc gacgcgcttg
     2581 ggatcggctg atgcaaaagt ttggattcat aattgccaga agaaagtgca cgaagctttt
     2641 cttcgatttt cccgtatttt gccttttgaa taagtgataa caatagaaat acgatcaatc
     2701 ctacacctaa tgaaattgcc atcaaatgga agataagcgg aacgtataat aaacgcgcac
     2761 gcagcaattc tccccaccaa tgactttggt tactggcata aaaataagtg aaaagtgaaa
     2821 atagaataat aaggaaagcc gcaatccccg aataaacagc tagcattgct ttggatattc
     2881 ttcccatcat attcgtatca cctcgacatc tccaaccaag gtattggtaa tgatcttcaa
     2941 tctgcgagga ttttcatcat aatcactgct gcagattttg atctgttcgt tttttaagga
     3001 aaactgctct tcttcaaaca agacatttcc tactaatgtc gcatgctcta aacgaatagc
     3061 cactcccagg ggtactaaga tccgtgttct gcctatccct tttcttacaa tcacaatatt
     3121 atcatctttt ggcaaaagtg tattacccaa atcgatgata gtatcaccag aaatgatggc
     3181 aatgttgata tcatcccatt catagacgtc gtttccaata cgttggttac caaataattg
     3241 ctgtctttta cgctcattat tatgtgtttt taattgctct gtttggacca tcatgatctg
     3301 tttttttcgc caaaaagcat tttttgtcaa atctattcct gaaatctcta cacctttcag
     3361 cccgataaat aaaacggcca atacaaccat catccataaa gcaggactgt tgactaagct
     3421 aaaaaaaatg accaagctcc ctaagatcaa ttgaaaattt tgaaatttag tacgaggata
     3481 tttgcgcata gctagatata tattgaaaat accgaatatt actaaaagca aaagtccagt
     3541 attgtttacg atttgccaaa cagcaaataa cagcagcagt gcttcgacta ccacaaaaaa
     3601 acgccaagaa ctattcatcg ctttttctcc ctcctgacac attctcattt catcatacct
     3661 atttttttga ctgttggcta taggacttta gatgtaagat cgttcagtga aacctgcaat
     3721 actcaaagag aaaagatcta gagtgcgtca tcagtaagat gaactctcta gatctttcag
     3781 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggtgtagca
     3841 atggttactt catcattttt acgtttgcca atcaatgctt gcgcgatagg agaatcattg
     3901 gaaatctttc cagaaaacgg gtctgcttca gcacttccga caatcgtgta ctcttcttca
     3961 tctccatcag gcaactcgat gaacgtaact gttttaccga tcgatacctc atctgcatct
     4021 acgccgtcat tatcgatgat ttgtgcaaaa cggatcatat tttcaattgt tgtgattctt
     4081 ccttcaacaa atgcttgttc atctttagct gattcgtatt cggagttttc ggaaagatct
     4141 ccgaaaccgc gagcgatttt gattcgttca atgatttctc cgcgtttaac tgtttttagt
     4201 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
     4261 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
     4321 atagtccaaa aaagattacc acgcttttct taaaatgtaa atgtttttct aaaaatgatc
     4381 aatgactagc ccctgttttt ctaagaatta tttacatatt tttgcactag ttccatatgt
     4441 tcttcatacg ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
     4501 tagtcatttt ctgctggttc taatactgcc ttgattgcct tttcgcttgg attgtcaaaa
     4561 ggaccaggcc catagccggt attggtatac aaattgtatg gtgaatctac agctgtatct
     4621 tcatacgtca ccaattcttt atgttctcct aatgcatata aaacagagat atctgactga
     4681 agtggcatat ttgccttgat tcggttaaag aagacttgtg caatattttt acgatcattt
     4741 tcttttacgc cttctttttc aactagagaa gccaaagtta aaacttcttg tacagtcaaa
     4801 tttttctgtt tgatagctga ataatagttt tgcatgaccg tatttgtctt gttcaccatc
     4861 tcaatcacaa gatccttaag cgaagtactc gtgtagtaat cataagtagc tgggaataag
     4921 tagccttcca aacggtattt tgtgttctca gctttagagg cactttccaa caattctggg
     4981 aatttttgat acaactcgtt aaagaaagtc tcatcattta ctaaatctaa aaattctttc
     5041 ttgtctttac ctgttacctt cgctacccgc tcagcaatct gatcgatgtc gtagccttct
     5101 ggaatggcaa ttttcccatc tgcaactttt gttggctcag atgtgccgcc ttcttgcaac
     5161 tgcttgccaa tctcatcaag agtcatatta ggcgctaact gataataacc agcttgaaag
     5221 ccagttaagt ttttaaattt tgtataataa ttgaaaacaa tcccactttt aataatattg
     5281 tctttctcca aaatttcgcc aatctgctta ttagaagagc cgtttgggat ttccacttgg
     5341 actaattggt cgtccgattt atctaaaggc ttcaacccgc tatctacata acgatatacg
     5401 gtaaacccga gaaatccgcc aataatcaat aatgtaagag cgatcactaa aatgatcttc
     5461 ctcacgatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
     5521 gctgccttac tggcttcttt tttgtctttg cttgggtgtt gtttgtttcc tgacaaaaca
     5581 actcctcctt actatcatct tcgtaactct gtttattata catgaaattt ctactgccgt
     5641 gaattatttt accaaatatt atgtcaaaat tgtaagtggc aaatgctctt tttgaggatt
     5701 acaatgaaaa atagttaaaa atggatagaa aggatttaat atggcaaaag gaaaacatca
     5761 aaaaaaacag cagatctctc tttcttttct cgcagttttg ttgctggctg tcagcttctt
     5821 ttcaacaggc atcattacag gatggcaatt aacaaaacaa cctcaaccac aaatttataa
     5881 aacggaaccc gcacaacttg cttccaattt aacatctaat gagcagatgc ttgccagcaa
     5941 aattgatcaa ttactgcaaa aatcagatta tatcggttcg atttatgtac gcaaaaataa
     6001 tcgagtgata ttagaaaaag gatatgggta cgcaaatcta cgcataaaag aatcgaattc
     6061 tccttctctt tactatcaaa tcggttcgat ccaaaaagcg atgactgctt tacttatcct
     6121 aaaacaaatt caatctggca agataacttt tgacacaaag ctatctgaat tttatcctca
     6181 gattcctgga agtcagcaaa tctcaatcaa aaatatgctt tacatgcgct ctggtcttca
     6241 tcgaaccgct tctccaaaaa aacctatgtc agatagtgag atcattcagt ttgcccttca
     6301 tcatttgaaa tttactggtt atgatacgta tcattatgaa ccattaaatt atacattgct
     6361 tacaggggta ttgatcaaac taatgaatca gccttatgaa actcttttaa aaaaagaaat
     6421 cattcggcca ctccatctag aacatacaga tttttatgaa aatgtaaaaa attcccctca
     6481 gcatgctgta tcttaccaaa tgtctgcaac tgacgattat tcaaaagcat tggtcgagcc
     6541 tgaaacagac atccgaaatg aattaggcac aggaaatata agtatgtctg tttatgactt
     6601 gaacaaattc tttaccagtg ttctgtctgg cgatattata ccaaaagaac tacttttctc
     6661 attgtggcaa aataatggtg ataaacatcc ttacagcggc ggtgtttaca gtggaaatga
     6721 ttatatcctt gctcagggaa atatcaatcg attccatgca gtagcggcga tgaaaaaaga
     6781 cacaaaagat gcaatcgtca tggaaagtaa tatccaatct gataaaaaca tcaaattgcc
     6841 ggccactgat ttaagaaatc agatttacga actgatggaa ggtgttaatt taaaaagcta
     6901 agtcgagaca aaaaaaccag caggatgctg gttttttgtt tcaatcgatt tctgtcttta
     6961 aataacgttc cattccgttc aatatatcaa atttgggttg ataacctaaa gaacggatct
     7021 ttgaaatatc cgctaaagaa tcacgaatat cccctgaacg ctccgcttca tatttaagcg
     7081 ctagctctgt tcctaagatt tgatcaattg aatgaatcaa ttcaagtagc gtagtgcttt
     7141 ttcctgtacc gacattgaat tgctgtccta aagctttttc ttccttagca acaagtaaaa
     7201 gtgcttgtat aacatcttct atataaacga agtctctaga ttggctacca tcaccaaata
     7261 aagtaaattc tgttttttct cctgccaatt gttttttgta tcggtccact agaatcgaaa
     7321 taactccgct atatggagag ttaggatttt gatttggacc ataaacgtta aaaaatcgga
     7381 cagcactagt cggaacatca tataaatgac agtaatccaa aacatattgt tctgatgcaa
     7441 acttatcgat ggcatatggt gttaaaggac ggatgaccga ttcttctttt tttggcaacg
     7501 ttggttcatc gccataaact gcagctgatg aactaaatac caatcgtttt aaaccagatt
     7561 gatattttcg taccaattca agcaataaaa gcgcactgtc aaaatttaca cgatgagttt
     7621 ctagaggacg ttctacagaa tctgccacac tagctacagc agctaaatga aaaatatagg
     7681 caaactgata ctgtttcatg attctttcca tcaattgagg atctgataca tccccctcaa
     7741 tgaaagtcac ttgtttctcc atatccaagt tttctttttt tcccattgat aaatcgtcga
     7801 ctactacgat tttgttttct tttcccaaat aattcgctag cgttgaaccg ataaaaccag
     7861 ctccaccagt aatcaatata gtatccatca aattcactcc aattatgcat tctcatactt
     7921 aataaagtta gtttaccatt tttatattgt aaaaactata aaatttgttg aagttgggat
     7981 aactagtttt cttttctact ttatatacct aaaaatagtt tcaattagtt actccttctt
     8041 ctttagatat agttttttgg atagaaccca gatatcccca aaaaataaat gaacctatcg
     8101 tactaaccaa aatgagttct gtgataaata atgccgaaac tgctattgta agaatcatta
     8161 aaatagcaaa aaagtgctta tcttttacta gatttggttg tgtgaaacaa taacgcaaag
     8221 ttttaaagca ttggataaat aagaaggtta acaatgtcaa tagacctaat cctcctgtag
     8281 cagccataac taagaaaata aaattatgag cagttaaagt atcttttccc attaatgtat
     8341 atggtagttt atcatgtgcg tattcaatat agtatcctgg agaaccgccg gatatcggct
     8401 tactcttgaa tatttcaatt gcacttttcc aaagtccaaa ccttaaatta gaaacatccc
     8461 cgccatcagt gtcagggcgt tttaaatcaa ctttattgct gctagttgtt cctgatgaat
     8521 cagatatatc tttttttatt tctgtaatat gcggaacatg tgcccatgct tgagcagtta
     8581 tatctgttac ataatacatc gcaattatac ttagcaatcc tactactaat gcagttagcc
     8641 atctttttaa agtattagtt ttaagaaaac gactactata acttgtaaag aaactaaaaa
     8701 caaaagttgc tattaataaa caaactaatg tggtgcgtga gcccgataaa gcaataaacg
     8761 agaattgaat aaaaatatta attgcaaaaa atattttaaa tagaagattt aaatgcttgt
     8821 aagtgaccaa ataatatata gcaataatga tgacaattaa tgatataacc gcaccaaaat
     8881 ttggatctgt atatacacca aataaacggt tgcctaacca ccctaaacga actgggtaat
     8941 acttatattt tattggaatt tttatgccat attgaatgac aaaccagtat aatgatacta
     9001 aattagctaa aaaccatacc aatgaaagta tccaagtaaa tactttgaaa aaaaagttac
     9061 tactgtagtc tttgccaaac tgataaatca taaagaaaaa gattaattgc cacatgatta
     9121 acttgatatt ttcgctatat ccatatttta aattcattaa actgcttact agcatcgcgc
     9181 caataaaagc aattaatagc caatcatatt ttttaagatt tttttctcta aatgcaataa
     9241 ttgcatctat aatgatcaag acaactcccg ctattccagc aggccaaaaa agtaaagtat
     9301 catatctagt aggtaatagt aaatacgggc ctattgctcg taacattaga ataaaaccaa
     9361 aataaataaa ataccaacct ttcacatatt ttaaaaattt ttcattcaac atttttcctc
     9421 catccaccta tttctcataa acatttctta tcctttttag gataaactgg ttctttcaat
     9481 tctaacaaaa aaatgctaaa ctaacaatgt atattaatga atttcgagag gtgaaagatg
     9541 aaaagagtaa ttacttacgg tacctttgat ttgcttcact acgggcatat caatttactg
     9601 aaacgagcaa aacaatatgg agattatctt attgttgccc tttctacaga tgaattcaat
     9661 tggaatgcga aacaaaaaaa atgttatttt agttatgaaa aaagaaaaca gttacttgaa
     9721 gctattcgct acgttgattt agttattcct gaagaaaatt gggaacaaaa agtaaaagat
     9781 ataaaagaat accatgcaga ttatttcgtg atgggcgatg attgggctgg acaatttgat
     9841 gaacttgaac aactaacaga tgcacaagta atttatttac caagaacacc tgagatctct
     9901 acaactcaaa taaagaacga acttaattct ttaaatagtg ataaataata ttttttaaac
     9961 aatgaaagaa caatatatct ggataagacg taaaaaaatg gctctataat ttctaggact
    10021 gatagaattt tctgtcgatc ctagattttc ttgtaaaaaa aacagacata caaaaatttc
    10081 gataaaatag agtcgtctaa aacatcaatc tgaaaggaag attttgtata tccatttctc
    10141 gttctatcaa agagcacttc actattaaag ataaaaatat tgaaattaat tcttttcaaa
    10201 aaacttttta taaggacaag aaagccatcg taatcgaagg tacattagtt cgcactttta
    10261 gacattgtct attttgtaaa gaaactgcga agcagctcgt gaaaaacggc aagaagattt
    10321 caatgattat cttaaatcgc agtgggaata aataaaccta tttgcgtctt agaaaacaac
    10381 attaccacta ccaatcatgc ggaaaatatt ttactgctca tacgtatctt gtcgttcctt
    10441 catgttttat ttcgaaacaa gttcattaca cgatattaga agagttgacc gagcgtcaag
    10501 cgttaaagac acttacgaaa cgttgtgatc tttcagtaac gacatttcaa cggacattat
    10561 ctgctctatc ggcaatgctg cgacagatgc tagactattt acctcattgt ttactattcg
    10621 acgagtttcg ctctctttca atttcccatg gaaagttctc cttttcttgt atgaatagag
    10681 agacagggaa gctctttgac attttgtcca gccggagaaa aaaagatttg attgcttatt
    10741 tcatgcgttt tacaagaaaa gctcatatgg gggttcgata cattgtcaca aatatgaatg
    10801 ccccttattt ttcattagtc aaagagtcct ttccaaacgc ccaaatcatc attgattgct
    10861 ttcacattgg acaacacttg aacaagtttt tcgatcgtgt tcgaaaacgt gtgatgaagc
    10921 agttgaatca aaaagacact tcacaagcta agtactatcg acaattgaaa cctttgtata
    10981 aattacttct aaaatcagat gacgagttgg attacacaac attcaagaaa tggcagaatt
    11041 ttcaatggcg ctatttaaca gaaagtgaag tagttgatcg tctaccctca atctcttatg
    11101 aacttaaaat tgctaagcag tttatcaaaa gctgcttagc aattatcaca agaaacagct
    11161 agctacttcg agaaacgacc aaagaagttc cctcgaaact tcactatctc aaaaagcctt
    11221 tttcatatct gaaaaaggct tttaactagc attttcgaaa aagtattcta ataacaaaat
    11281 tagagaatct tcgcacacat atcaaaacat tgaaacgatt tgcttatggg tttcgcagtt
    11341 ttaccaatat gcgcttgtgg atttttctaa tcaacaggtt aatcagctat gcattaaaag
    11401 ctagtaactc ttactaactt tgttgttcat aaatgacctt atcagcccga tttgacaaag
    11461 aactactttt ttacaacatt attttatttt cgagtaatct ttcttatttc atttcgtata
    11521 tctggaaaaa gaaaataaac aaacggaaga taaataatga aaatcattat tgatttaatt
    11581 gccatatcta aaaatgaaga agagaataat tgtggaagaa agtaataggc ccaagtagtc
    11641 aaagtaagat tgactataaa aaataagata acgttcttcc caaagaaata ggatattttt
    11701 atttcttttc gtacaaaaaa tactctaaag aaaaagacta ataattctac taccacgagt
    11761 acgatcgtag ccgctacagc gccataagta ggcacaaaag ctacatttcc aataatactt
    11821 acaatcgcac caatgatcat tggataagca tactccttat ctttttctat agcaattgca
    11881 aattggttag caaaaactcc accaattgga ctaacaacta taattagaca agaaataagc
    11941 atgtttattg tcatcggttt gaaattctcc ccaaaaaacc atggaacaaa ttcttttgta
    12001 ttgataaaca ccacactaaa aagaattaat gcaatgataa tcgtgtaatc aaaagatttt
    12061 tttgtgtaaa ctaaaatatt ttctgatttc ccctctgcct gtgctttaga tattttaggc
    12121 aacataacaa tagtaattga tgttaagact gccaatataa tacgagcaat tttttgagac
    12181 tgatcataat aagataattc cgttggatcc acaaaatacc caactatcgt tttgtctaaa
    12241 gttgtgtaca cttgcataaa caactgagga gtcaaaataa taaaagctgg tttccacaac
    12301 tgtttaaaaa cattagagtt aaagattggt ttacctactt ttccgtggat acttaaccag
    12361 aaaactaaac ttcctaaaaa gttagtaatt gaagtaatga acacgtaaat ccacaaatca
    12421 tctttagttg aaacaaaaat gattattaac aataccgatg ataatttgat aactgtattt
    12481 ctaataacca ctttcgaaaa ttcttcaatt ccttgaaaaa accaagaaat atctaatgtt
    12541 agccctacaa taaatatcaa ttgaattaag tataaatttt tatactttac atcaaaaaaa
    12601 taaatatagg ctatatagag aaaggaaaca ctcaagccta ttaaaaattg aataaagtaa
    12661 atattccaga attgtaaaga tagtgctttt ttatctttcc ttgatttagc gatatttcga
    12721 atacgaaaag gattcattcc cacagcaatg acagtcatta aaaactgtga tattgagaaa
    12781 acatacccat aaatccctaa accagttgaa ccaattctac gactaagtat aggtatagta
    12841 agtaagggta aaacaatcaa aaagacttga tatatcgcat tataaaatat atcttttact
    12901 gtttttttca ctttatatcc ctctctatca actcaagaac cttttctgta cttgctcctg
    12961 tttcataatt tccaatataa tcaagtaact cttgagaact tttcaaaagc ttttcttgtt
    13021 ggtttttaaa aacatcaaca aggccataac tatcttgtac gcttataatt ggtaactcac
    13081 ttaactgtat ataaaaacct ctttctaagc tatattcttt ttcatcatag ttaaaaagaa
    13141 taattggttt ttttgttagc gcaaaatcga aaaaaataga tgaataatct gtgattaaaa
    13201 catctatctc ttcaaaaagc atttcaagag gaatcccatc attaattaaa gtaatttgat
    13261 gttttttcat atattctata cttttagaat cagttgctaa tttactatga acattaggat
    13321 gaaatttagt cataaaattt aattcttgtt gttgcttttt aaaaaattca cgtaagttat
    13381 ccacacctaa ccattctagt tgcgtaattc cgttgtcctc aatattattt cgaaaagttg
    13441 gagcaaataa gacattgatt tgtttctttt tcaagtcaaa cacttgctct ttactagagg
    13501 ctaattcatc gtttctagga gttcctactt ctaatatttt agaaggaacg atattgaatg
    13561 ctgaaacata cttcttagaa ctatagcgat taccagataa taaatatgta attgactcac
    13621 tatctttttt cgcatagctt aggtaacgtt taggtaactt atcttttgca tcaaattcaa
    13681 ttttttttaa aggcgttccg tgccatgttt gaaaataaag ttgttttttc ctttttgcat
    13741 acttaatcgt tttccgacta tcgtctatcc aatacttagc tgtatataaa taaaaggcag
    13801 ctaaaaaaga atcggagtca attcttttaa tataatctgg taaatcagtt ataatcgctt
    13861 cttttttgat taaccaaata attctgtaat tcaatttttt ttcatgaatt t
//
LOCUS       DAJSMK010000063        13875 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.066, whole genome shotgun sequence.
ACCESSION   DAJSMK010000063 DAJSMK010000000
VERSION     DAJSMK010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.066"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            168..362
                     /locus_tag="ON488_001873"
     CDS             168..362
                     /locus_tag="ON488_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232064.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="ON488_001874"
     CDS             631..930
                     /locus_tag="ON488_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232065.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="ON488_001875"
     CDS             complement(1027..1461)
                     /locus_tag="ON488_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232066.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="ON488_001876"
     CDS             complement(1693..2403)
                     /locus_tag="ON488_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HCR3232067.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="ON488_001877"
     CDS             complement(2393..3253)
                     /locus_tag="ON488_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HCR3232068.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="ON488_001878"
     CDS             complement(3258..3896)
                     /locus_tag="ON488_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HCR3232069.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="ON488_001879"
     CDS             complement(3911..4210)
                     /locus_tag="ON488_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3232070.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="ON488_001880"
     CDS             complement(4253..5737)
                     /locus_tag="ON488_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HCR3232071.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="ON488_001881"
     CDS             complement(5757..6218)
                     /locus_tag="ON488_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HCR3232072.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ON488_001882"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="ON488_001882"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HCR3232073.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="ON488_001883"
     CDS             7521..8291
                     /locus_tag="ON488_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HCR3232074.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQAGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="ON488_001884"
     CDS             complement(8564..9391)
                     /locus_tag="ON488_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232075.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="ON488_001885"
     CDS             9959..11194
                     /locus_tag="ON488_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HCR3232076.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="ON488_001886"
     CDS             complement(12193..12453)
                     /locus_tag="ON488_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HCR3232077.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="ON488_001887"
     CDS             complement(12480..13781)
                     /locus_tag="ON488_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3232078.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
BASE COUNT         4469 a         2833 c         2181 g         4392 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaag
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcagccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tattt
//
LOCUS       DAJSMK010000064        13808 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.067, whole genome shotgun sequence.
ACCESSION   DAJSMK010000064 DAJSMK010000000
VERSION     DAJSMK010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.067"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ON488_001888"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="ON488_001888"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HCR3232079.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="ON488_001889"
     CDS             complement(2261..2512)
                     /locus_tag="ON488_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HCR3232080.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="ON488_001890"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="ON488_001890"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HCR3232081.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="ON488_001891"
     CDS             3462..3680
                     /locus_tag="ON488_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232082.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="ON488_001892"
     CDS             complement(3969..4481)
                     /locus_tag="ON488_001892"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HCR3232083.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="ON488_001893"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="ON488_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HCR3232084.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="ON488_001894"
     CDS             complement(6934..7377)
                     /locus_tag="ON488_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HCR3232085.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="ON488_001895"
     CDS             complement(7378..8166)
                     /locus_tag="ON488_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3232086.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="ON488_001896"
     CDS             complement(8163..9104)
                     /locus_tag="ON488_001896"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HCR3232087.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="ON488_001897"
     CDS             complement(9281..9868)
                     /locus_tag="ON488_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HCR3232088.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="ON488_001898"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="ON488_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HCR3232089.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="ON488_001899"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="ON488_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HCR3232090.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="ON488_001900"
     CDS             complement(12785..13720)
                     /locus_tag="ON488_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3232091.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRETKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3808 a         3096 c         2434 g         4470 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgtttcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataac
//
LOCUS       DAJSMK010000065        13734 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.068, whole genome shotgun sequence.
ACCESSION   DAJSMK010000065 DAJSMK010000000
VERSION     DAJSMK010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.068"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(260..547)
                     /locus_tag="ON488_001901"
     CDS             complement(260..547)
                     /locus_tag="ON488_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCR3232092.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
     gene            complement(537..866)
                     /locus_tag="ON488_001902"
     CDS             complement(537..866)
                     /locus_tag="ON488_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCR3232093.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            1171..1500
                     /locus_tag="ON488_001903"
     CDS             1171..1500
                     /locus_tag="ON488_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232094.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            complement(1787..2272)
                     /gene="vanZ"
                     /locus_tag="ON488_001904"
     CDS             complement(1787..2272)
                     /gene="vanZ"
                     /locus_tag="ON488_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCR3232095.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(2425..3336)
                     /gene="vanY"
                     /locus_tag="ON488_001905"
     CDS             complement(2425..3336)
                     /gene="vanY"
                     /locus_tag="ON488_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCR3232096.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            complement(3764..4372)
                     /locus_tag="ON488_001906"
     CDS             complement(3764..4372)
                     /locus_tag="ON488_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCR3232097.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(4378..5409)
                     /gene="vanA"
                     /locus_tag="ON488_001907"
     CDS             complement(4378..5409)
                     /gene="vanA"
                     /locus_tag="ON488_001907"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCR3232098.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            complement(5402..6370)
                     /locus_tag="ON488_001908"
     CDS             complement(5402..6370)
                     /locus_tag="ON488_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCR3232099.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            complement(6585..7739)
                     /locus_tag="ON488_001909"
     CDS             complement(6585..7739)
                     /locus_tag="ON488_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCR3232100.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            complement(7717..8412)
                     /gene="vanR"
                     /locus_tag="ON488_001910"
     CDS             complement(7717..8412)
                     /gene="vanR"
                     /locus_tag="ON488_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCR3232101.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGDVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            complement(8626..9201)
                     /locus_tag="ON488_001911"
     CDS             complement(8626..9201)
                     /locus_tag="ON488_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232102.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            9347..12271
                     /locus_tag="ON488_001912"
     CDS             9347..12271
                     /locus_tag="ON488_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HCR3232103.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            complement(12356..13216)
                     /locus_tag="ON488_001913"
     CDS             complement(12356..13216)
                     /locus_tag="ON488_001913"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCR3232104.1"
                     /translation="MEYLTIEELKHKYPVIHLCDILGIAKSSYYKWLKREPSETELKR
                     LKLMRAIKGIHEAFGGIYGYRRMTIFLNFFRRAKVNHKCVHRLMRIMGITAVIRRKRR
                     NYVPHKAVHVAENILNRDFHAERPMEKLLTDVTEFRLTNGTKRYLSAIYDLGSKKIVA
                     YKTSHRNDNPLVLDTLKQILGDVKPETTLIHSDRGSQYTSHAFNKMIKDHQIIHSMSR
                     VSKCIDNGPMEGFWGTLKVEMFNLDTFDRPAYLDRKIKAYIAFFNNERVTLDMGLAIP
                     TEEKILQMIA"
     gene            complement(13204..>13734)
                     /locus_tag="ON488_001914"
     CDS             complement(13204..>13734)
                     /locus_tag="ON488_001914"
                     /inference="COORDINATES: protein
                     motif:HMM:NF013677.1,HMM:NF024908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232105.1"
                     /translation="RSYSKEFKQKIVAEYLQTGYGFSYLAAKYNIPSKTTVNKWVIRY
                     TEGKENETYSPKSEVYNMTGVKKSYEEKLKIVEDYIANRLTYLEAAEKNHVSYSNIYS
                     WVNKYKKHGPIGLEDNRGRGKPTEIQTTEERLNAEVETLKARNKWLEMENDALKKRRK
                     IAGNHKSQGLDKKWNI"
BASE COUNT         4073 a         2759 c         2462 g         4440 t
ORIGIN      
        1 atctataata tttatgggag aattagagtg atttttttat tattactaaa aaacaatata
       61 aaataacgca ttttaagccc tctttgtgca taaggatgaa gcttttaatt tgaaagaggc
      121 ttaaaatgcg ttttaatttt ttctattttt cataaatata taggttagtg gtttaaaatt
      181 atagggtatt acaactctca gctgttaaaa attatctttt aaagtgtcgt ctatcctctc
      241 aagttgaaac attgggttct tacctaatct tttttaattg ttcataaaaa ttttcatgcg
      301 ttccacatag taagataggt atcactgcat tatctttaat ttcatatgca acgcgatatg
      361 tcgtacctgc atacttgaat ccaatagccc aaattcctga taaatcaccc gttttttgtt
      421 ctcccgaatg aggacgaact gctatctcat cataaattat cgttaaaaat tgttctttta
      481 atgttttctc ttttaatttt tttagatact ttattacgtg tttagaaggt agaatctcat
      541 aagccaattt ctgctgccaa ctcctctttt gtcatcggtt tagaatttgc aacagtatct
      601 tcagcaatag atttaaatgc agaagttaac gcattttttc tatttctaaa ttcttttaag
      661 atctcttgtt tgctataacc ttctgaaaga atatcagcca aaatatcttc actaaaatca
      721 aaaaattctt ttttaggctc tacaaactca taaaggatac cattctctac aagcttagct
      781 tctacttcaa caccattggg cacatcgaat tctttaggga ccgttaacat aatagaattt
      841 ccttgttttc ttgtttttgt aatcatatta tttcctccat tattttacat ttcgtaatta
      901 cttagtaatt acattgtacg ctatttttag tagaaataca aaataataaa actcctttag
      961 aacaattttc aaaggagttt tatttgatta ggaaattatg tagaataata atatgttttt
     1021 aacttggaat caaaaacgca cttgcaagta agtttacttc aatacatgaa attgcttata
     1081 atagtgtatt ggaattaagg tagattgaca aaagagtgat caaataggta tacttcattc
     1141 aaataatcgt ttgaatgtga ggtgagatga atgaaaaaag tttgccaagt gactgtcgta
     1201 cataaagaaa aagtaaatgg aataaaaaat aaattggatc aaaaagattt ttcaaactta
     1261 cttgtgttag ggaaatgttt cagcgatttt tctagaatta aaattttcta tgctttagaa
     1321 acctataagg aaatgtgcgt ctgtgattta gcagaaatac ttactgctag tgtcgctaca
     1381 acgtcacacc atttacgttt tttaaaaaaa catggaatgg caaaatcacg tcaagatgga
     1441 aaagtagttt attactcttt agcgaatgaa gacatccttt ccgctattcg tgttttttaa
     1501 agttatcaga aaatctatct atgaaatctt agtttggggg taccgtcagg aaaatgcgga
     1561 tttacaacgt taaggaaatt tattaaagag accaattcct cagcactaaa attgataatt
     1621 gggctttctt tgttactata gtgttaggta agctttttac tttatcaccg gttttcccct
     1681 cacttcacac ctacgggcga gtttccccac atcccgtttt ccatctaatc caattcattc
     1741 aatatcttta tgtgtatgaa agatcagatt gcttgattta gacatcttac acgtaattta
     1801 ttcttaaatg ggtacggtaa acgagcaata atacgagcaa aagtatacct acaaaaataa
     1861 taactctgtc taattttttt tgattcatat gcttattgct taaaccatat aatttcagtc
     1921 caagaaagcc tccaacagta tttgtaatta catctgttat gtctgtcgct ccaatagcga
     1981 agataaattg aattatttca aaagtaagac ttaaaaccag tacaaaagca aacttaggta
     2041 aaaatccgat ttctttaaaa ttgacattca aaagcaagcc aaatggaata aagattataa
     2101 cattatctat catctctctg aaattcccag tagcagtaaa tggagtcaag ttaagacttc
     2161 tttgatgata attaaatact gataaaatat tgtattgtaa tttgaataac actaaccaga
     2221 ttagtgtcac taaatataaa gctagcaatc ctctagataa tatttttccc aatataattt
     2281 cctctaattc ttttgtttaa gttgtatcat tagtatagca atgtcctagt taacgtgggt
     2341 tttaaattaa aaagctaacg ttaccccaaa agtgctagta caataatgct gttcattaat
     2401 ttcgttggtt tcattccgcc atccttacct ccttgaatta gtatgtgttg atccgggaaa
     2461 cactgtcaca attacaccgt ctatattgtt tcctgatatc tcataacgaa gattagtcgg
     2521 cacatgaatg gtggtatttt tagtaacagg ataataaaag atctcatatt tttccccatt
     2581 tacactaaca gaaatggttt tttcttcttt taggtaatcc atatattcct cgagaacgaa
     2641 attcttttct ttcataatcg cactatgtgg taaaccaaca tagcgaatat gccatagttc
     2701 atattgaatt cctgttaact ctgttttgtc ctctggataa cgtaaaatga acccgtattt
     2761 ccaagcattt tcttctatcc actttccttc aggggctcgt tccattttcg tcaagcttga
     2821 tcctacatct agtgataaac ctgaattatg ctcactataa cctgctggta aggcatactc
     2881 agcccccatt tcttggtaaa gcacactttg ctcatcaaag tctcgatagc cactattaat
     2941 aataaaatga ctaacgccac cctttacagc atcattgacc atctctgaaa atttttgtgc
     3001 tatttctttt gacatataaa tattactatc aagcaacccg tatccattta ttaattcgtc
     3061 atgtttagat aaattcacga tatctgactt cacactttct tggcgaacag gatatttact
     3121 attgattaat agcagatttc cttgataaac ctgttcttct gtaattgttt tctcttgggt
     3181 attttcagaa gtcccactat tttctaaatg ttctttggga ttttgatcat aattttgaaa
     3241 ttcgactttt tcctgagaaa acagtgcttc attaacgtag tcataaccta agtatattaa
     3301 gaataacaat aacaataaaa aaaacaactt cttcattttc agtctcctcc ttaactatat
     3361 agttggaagt atgaaatatt tctagaatct tccccttaaa cggcacaatc tcgtttgaga
     3421 ttgtgccgtt ttgccccgta aattacagtc aattatttcg ccctactgga tttactatta
     3481 tcaccaatgt agatgaattt tcataagtga tacccatgct gaatttaacg aggctgaact
     3541 gcctgttgac aatgggcggt gtgaaatacc acccctctat gcgatcagtc ttattatcag
     3601 gctatcttgc cgcagcgcac gcagataatg accgcaatat cgctctgcct tacatcttca
     3661 atactatcta ctatatataa attccctaag aaccagttac atacgtcggg tttcctgccg
     3721 aaagagttag cttatatagt ttgtccgtgc aacggttaaa agtttattta acggggaaat
     3781 caaaatagct attggggtat ggttcgtctc ttaatacata gtgccaccat tcgaggctat
     3841 atgcttcaaa cccactgttt tccatgatgg agcgcaaacg tctgcgattt tgcgcttcat
     3901 tgcatgatat tccatttgcc gcatgatgag agcgttcatc cataaaatca aatcggctcc
     3961 ccattggtac aagctcaccc gtgtctaatc gataaagcgt aagatcaatg gcactgccgc
     4021 ggctatggct tgattttgaa gccacgtatc cttttgaaat catctcagtt cggtcaatat
     4081 tgggataata actttccttt gtcaggttat tttccggctg tgcagcccat tgcataaaac
     4141 agtttacagc acgattagga cggtaaccgt cccatagaag caatccgtac ccttgggtag
     4201 cagccagttc ttttgccttc aaaagcgatt cagccaactc gtatgtccct acaatgcgat
     4261 ttacttcata accgtcaacc ggttttccgg tgaaattatc ccaagtggca tatttagcgt
     4321 cccaacgaac accgtgtact atttcatcta aaaaagtaaa tcctatttcc atgcttatca
     4381 cccctttaac gctaatacga tcaagcggtc aatcagttcg ggaagtgcaa tacctgcagc
     4441 ggccatcata cggggataac gactgtatga cgtgaaaccg ggcagagtat tgacttcgtt
     4501 cagtacaatg cggccgttat cttgtaaaaa catatccaca cgggctagac ctctacagcc
     4561 gagcgcttta tatatttttt ttgccgtttc ctgtatccgt cctcgctcct ctgctgaaag
     4621 gtctgcggga acggttataa ctgcgttttc agagcctttt tccggctcga cttcctgatg
     4681 aatacgaaag attccgtact gcagcctgat ttggtccacc tcgccaacag ctaacgcggc
     4741 actgtttccc aataccgcac aaccgacctc acagcccgaa acagcctgct caattaagat
     4801 tttgctgtca tattgtcttg ccgattcaat tgcgtagtcc aattcgtccg cgctattgac
     4861 ttttttcaca ccgaaggatg agcctgaacg cgccggctta acaaaaacag gataggtaaa
     4921 cgtagctgcc accggcctat catctttatt aataacccaa aaggcgggag tagctatccc
     4981 agcatttttc gcaacgatgt atgtcaacga tttgtccata caaattgctg agctttgaat
     5041 atcgcagcct acaaaaggga taccggacaa ttcaaacaga ccttgtatgg atccatcttc
     5101 acctgacttg ccatgcaaag ctgaaaatgc tacatcaaca tggttgattt catattcatg
     5161 gttcttttta acaagtaatc cgtgcatttt tttatccggc gagagtacag ctgaatagca
     5221 attgtcgttt tcccattccg cgcaaggttt ttcgcacatt ttccatacac cagatttcgt
     5281 aattccaatg tataacggct cgtatttttc tttattaatg ttagcggcta tctctattgc
     5341 agattttacc gatacgtcat gctcctctga gcaaccccca aacagtattg caacttttat
     5401 tctattcatg ctcctgtctc ctttcaaaat ccaaacagtt tttaatggtt ttttcaacgg
     5461 tatcacgcaa cgcttgctcg gtataatagg ccgtatgcgg tgtgattatc acgttaggca
     5521 ttctttgaag tttaagtaaa aattgattat caattggttt ttgggtgcaa tcagagtaga
     5581 aaaactcttc ctctccttcc aatacatcca atgcggcacc gcccagtttc ccgttttcta
     5641 atgctttaac caactcatag gtatctacaa gtggaccgcg cccagtattg ataagaaatg
     5701 ctccttgctt cattctctgt atttgttcgt ggctgataat atagtgcgta tccgtattga
     5761 gcggcacatg aagcgtaacg atatcgctat tttgcagcaa ctcatcaaac ggtacatagt
     5821 ttacctctat acttcggctg cgactataag ccaacacttt acatccaaat cctcgcagcc
     5881 gctcaataac cgctttgcct atctggcccg ttcccaccac accaactgtc atgtcgctga
     5941 gtaccttgcc acggtcgctg tccaacctga aatcatgttt ttccacagag cgcacaatcg
     6001 attttacgtt gcgtactgcc ataagaatta gcatcatagt ataatcggca acgctatccg
     6061 gcgagtacgc cacattgtcg acagtgatgc ccattctctt agcagcagtt gtatctatat
     6121 gattgcagcc gatgcttcgg gtagaaatat atttcacacc ggctctcttc agcgcaagaa
     6181 gaatagaggc ggaaatctct gatttatgtc ccacactgat acattgattg aaaggcgcgg
     6241 atttggcgtt ggattccgac acgttggcgt taattatcgt tgccataacg ccaaagcgag
     6301 gcgaaagagc atggaatgca tctgcctcat cctgctcaca tccataaaca gtaatgccga
     6361 tgttattcat aattaagacc aaccctttct gtgaaaggca ccaaataaaa cggggatgcc
     6421 aatggtaatc ttgtcaaatc tttctctgaa gaacgaaaac ggctcgttct tacggtatta
     6481 agtctaccgt gtaagaacga gccgtttctt aatattaaat tgttaatttc ctaagaaaaa
     6541 gtaaagataa ccttgagatt ttcctaaaaa attatataca tctcttagga cctcctttta
     6601 tcaaccaagt ctggcatcgc tggaagctct accctaaacg tcgtatagtt atcattgctt
     6661 tccgcgtaaa tctgccctcc atgctgaaca ataatttctt ttgcaatcgc caatccaagt
     6721 cccgcgccac ccgtatcgga agaacgagca ttgtccagcc tatagaactt ttcaaatatg
     6781 gcagctagct tatcttttgg gatgcttcca gtgttcttga attcgattga caccacatcc
     6841 ccggagaggc ccgcggtaat gtcaatgatg ctgttatcct cactgtatgc agcggcgttt
     6901 ttcaaaatgt tgttaaagac tctcgcgagt ttatcagggt cgccggacac ggtcagatcc
     6961 tcgggggcgt gaataaccgc ctgttttcca tgtgcggaaa gctgaggata aaattcatcg
     7021 gtcatctgca ccagcatata gtataggtct atgtgcgttt ttgttagcgt tatcgtttgt
     7081 aggttatacc gtgtaatctc aaaaaactcg tcgattagct gttcgagtcg atacgctttg
     7141 tccaacgtga tatgcacata ctttgccttt tgatctaccg gcatgtctgg agcctcgtca
     7201 agcaggctca aataaccgat aatggatgta aggggcgttt taatatcgtg cgccaagtac
     7261 ataacaacgt cattttttct ttgttcggcc agctttgcat cctgctctcg cttttccaga
     7321 gtccgtttta atgtgttgag cttttgttcc ataacatcca tttccgcaga aagctcaatt
     7381 tgtttatctt cgttctgaat aagtacatca atgccggtat ttatctcgtc aaagtatttt
     7441 gcgaattttg aaagcatgac gcgacataga ataagaatac taatgacaat cgccacataa
     7501 ataaagatat ctatattgtt ccgtatggaa tattgatata atttcatcgc gtccaggtga
     7561 tttaagtcat atttgttttc caaaatactt aagatccaat ccccaagttt ccctcggatc
     7621 attgaacgaa tatacaacac gaatacaatt gctaccacaa caattgcaac gatatacatg
     7681 taaagttttc gttctagttt ggaatagtcg ttttttttat ttttcaattt tataaccaac
     7741 cccccatacc gtttttatat atttcggatt atcaatggtg tcgttcattt tttcgcgcaa
     7801 atgccggata tgcacggtga tggtgttgtt gctcttgctg aaatattcgt cgccccatat
     7861 ctcatgaaat agcagctcgg agctaaccac atcccccttg ttttcacaga ggattcgcag
     7921 tattgaaaac tcggtgggag taagggataa ctgcttctcg ttcagataac actcatgggt
     7981 gttaacatta atgacaaggc cggagtggac gataacattt tcgttctgct cctttactcc
     8041 actgaatttt ttgtatcggc gcaactgggc ctttacccga gcaattaact ccagtgggcg
     8101 aaagggcttc gttatataat catccgcgcc gattgttaac cctgtaattt tatctacctc
     8161 tgtatctttc ccggtcagca tgataatcgg ataggtgtgc ttgtccctta ttttttgaca
     8221 gatagtaagg ccgcttgtgc cgggaagcat gatgtccaat atggcaaggt caatctcaga
     8281 cttgtctata cattccaatg cttctttggc ggtatagtat ttgaaaaccg tataattctc
     8341 gttttttaag tataattcaa ccaaatcggc aatttcatgt tcatcatcca caataagtat
     8401 tttatcgctc atagttatca ccctttcaca taagtttgcc cttaataatt tatcagatta
     8461 tagggccgaa tttataagca tttacataat aaatgactaa gaatttctta agatgatgat
     8521 tcttttttta tcaaagggct tttcggcatc gctaggaggc tgttaatatt ttatagtttc
     8581 cttttcttct ttaaaaatat tgcccattag cggaatacag aatggctaat tattcacttc
     8641 tgataatttc ctgtataatg aagccctaga tacattagta atttcacaaa tttgatttac
     8701 agtcatattt ccttctttat atagctttac cgcataattc attcctgcgt gatttttatg
     8761 atacttcttt aatcgacctt taaactttcc ttctttctta gccaattcaa tcccttcacg
     8821 ttgtctcatc cgaataagat ctcgctctaa ttggttaaca ccagccatta cagtaattaa
     8881 gaattggctg tatggattat cttctgataa atcaagccat gtatctttta gtgattttaa
     8941 acttgccttt ttatctcgta tgttatcgat taattcaaat agatcttgtg tactacgagt
     9001 gattcgagtt aagtctgtaa cataaatgat gtcatcttcc tgtaaatcgt ctaacacttt
     9061 ttgaagttgc tcgcgatcct ttgttgctcc tgaaactttc tcttcatata taatatccat
     9121 tccgatctcg ttcaactgct gaaattgtct tgaaggattc tggttagtcg aactgacacg
     9181 aatataaccg attttccgca aaatatcacc tcatttttga gacaagtctt atgagacgct
     9241 cttaactatg attttatcag tctactacat ttgtatcaat agagtacact ctattgatat
     9301 ataattgaac taataaattg aaaatacaga aatggaatga tactgaatga aaattgcgag
     9361 aggtagagaa ttgcttacac cggaacagag acaggctttt atgcaaatcc ctgaagatga
     9421 atggatactg gggacctact tcactttttc caaacgggat ttagaaatag ttaataagcg
     9481 aaggagggaa gaaaaccgtt taggatttgc tgttcaatta gctgttcttc ggtatcccgg
     9541 ttggccatac actcatatca aaagcatccc agattcggtc atacaatata tatcgaaaca
     9601 gattggtgtt agtccatcct cgcttgatca ttatcctcaa agggaaaata cactttggga
     9661 tcatttgaaa gaaattcgaa gtgaatacga ctttgtaact tttaccctga gtgaatatcg
     9721 aatgacattt aagtaccttc atcaattagc tttggaaaat ggtgatgcca ttcatctact
     9781 gcatgaatgc atagattttc taagaaaaaa caaaattata ctgcctgcta tcactacact
     9841 tgaaagaatg gtgtgggaag caagggcaat ggctgaaaag aagctattta atacggttag
     9901 taaatctcta acaaatgagc aaaaagaaaa gcttgaaggg attattacct cgcagcatcc
     9961 atccgaatcc aataaaacga tattgggttg gttaaaagag ccaccgggtc atccttcacc
    10021 cgaaactttt ctaaaaataa tagaacgact cgaatacata cgaggaatgg atttagaaac
    10081 agtgcaaatt agtcatttgc accgtaaccg cctgttgcag ctgtctcgct taggctcaag
    10141 atacgagccg tatgcattcc gtgactttca agaaaataaa cgttattcga tattaaccat
    10201 ctatttatta caacttactc aggagctaac ggataaagcg tttgaaattc atgataggca
    10261 aatacttagt ttgttatcaa aaggtcgtaa ggctcaagag gaaatccaga aacaaaacgg
    10321 taaaaagcta aatgagaaag ttatacactt tacgaacatc ggacaagcat taattaaagc
    10381 aagagaggaa aaattagacg tttttaaggt tttagaatcg gttattgaat ggaatacctt
    10441 tgtctcttca gtagaagagg ctcaggaact tgcacgtcct gccgactatg attatttaga
    10501 cttactgcaa aaacggtttt attcactaag aaaatatacg ccaacgctat taagagtatt
    10561 ggaatttcat tctacaaagg caaatgagcc acttttacaa gctgttgaga ttatccgagg
    10621 aatgaacgaa tctggaaagc gaaaagtgcc tgatgactca cctgtggatt ttatttcaaa
    10681 acgatggaaa agacatttat acgaggatga tggtacaaca attaatcgtc attactatga
    10741 aatggctgtt ttaacagaac ttcgggagca tgttcgggca ggagatgttt ccattgttgg
    10801 cagcagacaa tatagggatt ttgaggaata tttgttttcg gaagatacat ggaatcaatc
    10861 gaaggggaat acgagattat cagttagttt atcattcgaa gattatataa cggagagaac
    10921 cagcagcttt aatgaaaggt taaagtggtt agctgccaat tccaataagt tagatggggt
    10981 ttctcttgaa aaaggaaagc tatcacttgc acgcttagaa aaagatgttc cagaagaagc
    11041 aaaaaaattt agtgcaagcc tttatcagat gctaccaaga ataaaattaa ctgatttact
    11101 catggatgtg gcccatataa caggatttca tgagcaattc actcatgctt ccaataatcg
    11161 aaaaccagat aaggaagaaa caatcattat catggctgcc cttttaggaa tgggaatgaa
    11221 tattggcttg agcaagatgg ccgaagccac acccggactt acatataagc aactagccaa
    11281 tgtatctcaa tggcgcatgt atgaagatgc catgaataaa gcccaagcca tattagtaaa
    11341 ctttcatcat aaattacaat tgcctttcta ttggggcgac ggtacaacat cttcgtcaga
    11401 tggtatgaga atgcagctag gtgtttcatc actacatgca gatgcaaatc cacattatgg
    11461 aactggaaaa ggagccacca tctaccgatt tacaagtgat caattctctt cttactacac
    11521 aaagattatt catactaatt caagagatgc gattcatgtt ttggatggtt tgttacatca
    11581 tgagacggat ctaaacatag aggaacatta tacagacact gccggttaca ctgaccaaat
    11641 attcggactg actcatttat taggatttaa atttgcccca agaataaggg atttatcgga
    11701 ctcaaaatta tttacgatag ataaagcaag tgagtatcca aaactagaag ccattttacg
    11761 tggacaaata aatacaaagg tcattaaaga aaattatgag gatgttttgc gattagctca
    11821 ttctataagg gagggaacag tttcagcatc ccttattatg gggaagctag gttcctattc
    11881 aagacaaaac agcttagcta cagccttacg tgagatgggc cgaatagaaa aaacgatctt
    11941 tattttgaat tatatatcgg atgaatcatt aagaagaaaa atacaaagag gattgaataa
    12001 aggagaagcc atgaatggat tggcaagagc tattttcttc ggaaaacaag gtgagcttag
    12061 agaacgcacc atacagcatc aattgcaaag agccagtgct ttaaacataa ttatcaatgc
    12121 tataagtatt tggaatactc tccacctaac aacagcagtt gaatataaaa aacggacagg
    12181 tagctttaat gaagatttgt tacaccatat gtcgccctta ggttgggaac atattaattt
    12241 actaggagaa taccatttta actcagagtg aactgccccc tgtcaagtag acaggtaaaa
    12301 aaacaaagta ttttagacca tgcatgtaaa aatgtgtggt ctttttttgt agcgtttatg
    12361 caatcatttg tagaatcttc tcttccgtag gaattgctaa tcccatatcc aaagtaacgc
    12421 gttcattgtt gaagaacgcg atgtatgcct tgattttccg gtctaagtac gctggtctgt
    12481 caaacgtatc caggttaaac atctccacct tgagggtacc ccaaaagcct tccatagggc
    12541 cgttgtcaat acatttcgag acgcgtgaca tactatggat tatctggtga tctttaatca
    12601 tcttgttaaa ggcatgggag gtgtactggg aaccgcggtc gctatgaatc agtgtggttt
    12661 caggctttac atcacccaaa atctgcttta gtgtatccag tactaacggg ttgtcattgc
    12721 ggtgactggt tttataagcc acgattttct ttgacccgag gtcataaata gcgctcaggt
    12781 aacgttttgt cccattggtc aaccggaatt ccgtgacatc cgtcaataac ttttccatgg
    12841 gtctttcagc gtggaaatca cggtttaaga tgttttcagc cacatgtacg gctttgtgtg
    12901 gcacgtagtt ccttcttttg cgacggatga cggctgtgat ccccatgatt ctcatgaggc
    12961 ggtgtacaca cttatgattc actttcgctc ttctaaaaaa gttgagaaag atggtcattc
    13021 ttcggtagcc gtaaatccca ccgaatgcct cgtggattcc tttgatcgcc cgcatcagtt
    13081 tcaggcgttt taattctgtt tctgagggtt cccgttttaa ccacttatag tagctggatt
    13141 tggcgatacc cagtatgtca caaagatgga taacgggata tttatgcttt aattcttcaa
    13201 tagttaaata ttccacttct tgtctaaccc ctgtgatttg tgattcccag cgatttttcg
    13261 gcgctttttt aacgcatcgt tctccatttc tagccatttg ttccgggctt tgagtgtctc
    13321 tacttctgcg tttaaacgtt cttccgttgt ttgaatttcc gtgggcttcc cgcggccccg
    13381 gttgtcttcc agacctatcg gtccatgctt tttgtattta ttcacccagg aataaatgtt
    13441 actgtaactt acatggtttt tctccgctgc ttccagataa gtcaggcgat tggctatgta
    13501 atcttctacg atttttaatt tttcttcata tgatttttta acacccgtca tgttgtacac
    13561 ctcagatttc ggagaatatg tctcattctc ttttccttca gtatatcgaa ttacccattt
    13621 gtttaccgtt gttttagatg gaatgttata tttagcggct aagtatgaaa aaccgtaacc
    13681 cgtctgtagg tattcagcta caattttctg cttgaattct ttcgagtaac tgcg
//
LOCUS       DAJSMK010000066        13528 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.069, whole genome shotgun sequence.
ACCESSION   DAJSMK010000066 DAJSMK010000000
VERSION     DAJSMK010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13528
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.069"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            10..255
                     /locus_tag="ON488_001915"
     CDS             10..255
                     /locus_tag="ON488_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit S"
                     /protein_id="HCR3232106.1"
                     /translation="MIHVFSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEG
                     YKAKHPEAKPFKYPQEMKRAWRKMLDDELIPLENELR"
     gene            complement(2190..2855)
                     /locus_tag="ON488_001916"
     CDS             complement(2190..2855)
                     /locus_tag="ON488_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232107.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            3034..5016
                     /locus_tag="ON488_001917"
     CDS             3034..5016
                     /locus_tag="ON488_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HCR3232108.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            5020..5658
                     /locus_tag="ON488_001918"
     CDS             5020..5658
                     /locus_tag="ON488_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232109.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            5686..6114
                     /locus_tag="ON488_001919"
     CDS             5686..6114
                     /locus_tag="ON488_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232110.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            6571..7482
                     /locus_tag="ON488_001920"
     CDS             6571..7482
                     /locus_tag="ON488_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HCR3232111.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            7699..8136
                     /locus_tag="ON488_001921"
     CDS             7699..8136
                     /locus_tag="ON488_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232112.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            8231..9115
                     /locus_tag="ON488_001922"
     CDS             8231..9115
                     /locus_tag="ON488_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HCR3232113.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            9339..12506
                     /locus_tag="ON488_001923"
     CDS             9339..12506
                     /locus_tag="ON488_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232114.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            12526..13071
                     /locus_tag="ON488_001924"
     CDS             12526..13071
                     /locus_tag="ON488_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HCR3232115.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            13099..>13528
                     /locus_tag="ON488_001925"
     CDS             13099..>13528
                     /locus_tag="ON488_001925"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HCR3232116.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI"
BASE COUNT         4607 a         2144 c         2709 g         4068 t
ORIGIN      
        1 agtgatgatt tgattcatgt cttttccaat gagtggtttg tttctgagaa agaattacat
       61 gcttctaatc tgcaatatct accaggtgaa gatccaattc ctaatatgaa agcaattatc
      121 aacagtaagg attacgaagg atataaagcc aaacatccag aagcgaagcc atttaaatac
      181 ccacaagaaa tgaagcgagc atggcgtaaa atgttagatg atgagttgat tccacttgag
      241 aatgaattga ggtaaacgag aagagttaag aaaattgtac gattcaaaga tggtagtcaa
      301 gtggaagtgt agaaaatagg gatagatgtc ttttatttgt tcacatttta taacgaagta
      361 tttaagacag ctattgaata atgtttcctc cacctttttc attcatttac cccaccccgt
      421 tgttatatga ccgtgttttg agaggaacca ataaaaagca taggctaact aggggttcct
      481 ttttcttttg tttttttgga atccgcttaa gtgaaatgta tctgaaatga aacggagata
      541 aagtgatttt ttgctataat gacaaggttt tagctgtttc agataccatg taacccaaaa
      601 tagtttattg agaaaatagg agagtatttg atactaacta gtaggaaaaa atgagataaa
      661 aattaaatgg aatcatttca ggtaatctca aataaaaaaa tatacagtcc tgtggcactt
      721 tacctatggg actgtatatt ttttactctc agcgggcttg ttttgactcc gtgtctgact
      781 ccgtcgtatt gattttaaat gatattcgat gaccatttaa caggttattt ttgaaatttt
      841 tgtctctata tgactcagtt tgataattat tgatagatca atttgggtct atatcgaaca
      901 agggaataat ccaataaaaa atgatttaga atatcaaaat aacaaaaaag aggactacct
      961 gtattcgtcc tcttttttga ccagattttg accagtctaa tttacattct aatatattca
     1021 tatgagctaa ttttttgatt aaatggtaag tttttccttg tttgttttag tttaaactag
     1081 tgtgtaattt aaaaatctat atggaagggt ctgtggggta atacttaaat aaaggctagg
     1141 aacctgataa catcaaggtt cctagccttt ttataataaa atgaagcgaa aataatttct
     1201 tttaaagagc cgagattatc agctatataa gagtgaattt gatgcaaaaa acagagccga
     1261 aacagtcttg gtgttcgtag ctctgcttat atgtttcgaa tttaagacaa agagttggca
     1321 aaagatgttg ataaggaaga taagataact gtgttatata aactaggtaa ctaactgtaa
     1381 caagctaatt ttaagagatt cttattagaa gacgtttagg aatataacta agaaaatgat
     1441 tatacaggta attgtcattt caataatgtt ttctaatttt cgcgtctttg ttttaagaaa
     1501 aaggccagaa tcagttggaa aaaagttcgt acgatagtga agaggggcaa aatttcctac
     1561 taatattccc actaacaaga gataaaacgg ccaggttggt gtgattcctc tataaaaaaa
     1621 tgcccatgct accgaaatcc catagattaa caactgaaca atttttacaa tgaaaaaatt
     1681 gttctgccat tactcaaagt ctcttcctcc ttgtatcgtt tatttgtttc attttatcat
     1741 tatgataggc gcttgaacaa tccattttgt attttattga gtactcttgg ataaactacc
     1801 agcgattatc atatttattt atgttactgt aagccatcat ataaaagtaa atgagcagat
     1861 catagaaata taaaaaagaa ctaaaattga tctaaattat gtgcagcttg actacgtacc
     1921 aatctatatt acttactaga ttggtcgtta atctattcgg atcgaatgag caaaatattt
     1981 ttgtgaatgt ccatccttga ttatgattcc aaaaagaatc attgggaggc tgtggcgtaa
     2041 atattatact ataagccaga aatacctatc attctgaact tttttattta ggaactttca
     2101 tctcaaggct ttttcaatta atttgtaccc ctgttttttg gataagatca tgtgcattga
     2161 ttttttctat ctctacgttc atctcctact taatgcctat ctggctcctg agggcttctt
     2221 tttaaggcgt cgtcatagtc ttggctgagg atttcttggt aatctgaggg aatggcttcc
     2281 caagtgagca ggcgaacgtt catgacgtgt tttcctttgt gtttgattac agcatggttt
     2341 ttctcttttt ctacctctcc agcgtgaaaa gacagccatg taccatggcc aaagatatca
     2401 ttacataccc aacgttcgat ggaattgtcc acgtatccta cagggagtgt ggtatagccg
     2461 atttgtggtt tcaaaaaagg attgaatcga tcgatcgttt catttttgta ttgataattg
     2521 ataagaaaaa gatagaccaa acaaaagacg agcagaaaga aagatagtgt ctttttgagt
     2581 gagaagggtt gttttgatga ataagatttc ttgttaacaa gaggttcatc tggcaatgtt
     2641 ggttctattg attcggtagc tgattcaata gaaggaaaat caatcggcag acctaaagta
     2701 tgatgtaaaa gtgacagcat ttcaaggtct ggcattgtac gagaattttc ccaactagaa
     2761 atcgttttat cggaaacacc aattttttcg cctaattctt tttgcgtaag cttacaattt
     2821 ctgcggtaag ttcgtatttt ttctccggtg ttcatcttct tctcctttcg attctacagt
     2881 atatagattt attctacatg acctatacac ttgatagata cgtttttttg atgaaaaacg
     2941 gtatgatttt atcaaagaat catttaagta agggagagtg gtgataatca aaaaaagttc
     3001 acagttttac tcacaatcat agtgaccggt atcatgagtg gttttgcctt ggttagtata
     3061 aataaacagg tactctatcg gacaaatgaa tttttccatc aaacagatac ttatactccg
     3121 attcgattgc cacaacattt tattgggcaa gaagaatatg agcagctaat catggtattt
     3181 gaaaatgtct catcagaaac tgagctttct tatatgaaaa aaacagtaaa tgaatccaat
     3241 gaagtagata catcttggaa cttcaagata cagccaaagc ttgaaatgac attgtattat
     3301 caaggggatg tcaaatcttc tcacgagaag gtaccctatt ctaatacctc ctttcgcgta
     3361 acgtccattg aagaatcgat caaaataaaa gattttgaag gtgaattttt cttgatgacg
     3421 agagaaaaag aagcctatga acgggtcatt tcactattca ctgatcgatt caatcaagca
     3481 tttcacactg attatgccac taatattttt gaagactttg aaaatagcta ttcgtattcg
     3541 gttatttcaa atacagacgt atataattat cgagtgtatt taactattgg attgattctt
     3601 ttattccttt tgttatcatc ctttttctta ttgatgaata aagaaatcag tttattgttg
     3661 aataatgact tttcattaca tcaagtattg tggtgtttat tggggaaaaa gaaaatcatt
     3721 attacattca taattgcagg aatcattggt ggttttattt ttatgtatta taaggagcaa
     3781 tttctttatt tgttccagat gtacgttttc ttgttcagcg gaatatatgg tatctctttg
     3841 atttctcttt tattagttga aaaaatcgct tcgttaagag aagcgttcaa ctatatccaa
     3901 tacattcttt ttacatttgg attgttgttt tctcttcttt tgaccgttgc caatgtcgaa
     3961 ttagcaacta tcgttttttc ttcttcacag ttagctgttt cccatgaacc accaaaagaa
     4021 atcgctggtg aggactatca tgtattttat ccagtaacca tcgggaaaaa ccacgtggat
     4081 tttatttatt ccaatcgttt tgcatcagca gcagatcagg aattatatga aactttgaat
     4141 aaaaacggaa gtatattagt caatgtatca gattacttga atgaagaaaa tgaacagttt
     4201 ggcagaggga taaaaataaa tctgaattat cttaagaaat ttcctttgat tgatgtctct
     4261 ggaaggttga tccaaataac cgaaaaagaa acgcaccctg ttatattgat ccctgaacga
     4321 tatagacata cagatttaaa aaatgacctg gcgcaaataa cagaatatta tcaagaaatc
     4381 agtgaaaaag aaccgaaatt tctatttata aaaaacaatc aacccattta tacatttatt
     4441 ccttctatcc cctggatcga acattatccg gttgttgaaa tactgacatt gaaaaacagt
     4501 atgtatttgg aaagaaatat tctcagcgga gaaatctatc caccgttaaa gatcaagata
     4561 ggctctttgt cgaaagaaag gttatttgag ctgattgaag aaagtcagtt acgtgataac
     4621 ttgcagttat catttccgta tactcagact gaagagatag ctgtcaaagt gttaagcaga
     4681 tcatttcatt acttgataca gatattttta ctcactttct tttctttctt cttgttgagc
     4741 tatgtcatgt tatgcatata ttttgtctac aattgtcgga aaatcgctat ctttcgttca
     4801 agtggttatt cgctctttga aacgtataaa gatttcttca tgatgaacct catcaaatgg
     4861 ggaacgacaa gtgtaatctt cctttttctt atagaaagag agcctaaata tctttttaat
     4921 atttttttct ttagcttcat tgattttatt ctttcagttg tttttatttt gtctacagaa
     4981 aagaaaagtc agttattgct gatgaatgga ggttaacaat tggagccgtt gatagtgata
     5041 aaaggtgcga aaaaaatcat tcgaaacaaa acgattcttc atttggatcg tttcactgcg
     5101 gatgctgggg atcttgtgac tgttgttgga gaaagtggag caggtaaaag tacgttattg
     5161 aatatattag gattgaatga tcagttcagt tcaggacaat tctatttgtt cgatcaagag
     5221 acgaaacaat taactgggag agagaagcgc ttgataaaaa gaaataccat atcttttctt
     5281 tttcaagatt ttgggttgat tgaatatgaa acaatcgatt ttaatttaga tattggattg
     5341 aagttttcga atttaaatgt ttcagataag cgaacagcaa agtatgaggc attgaaaaaa
     5401 gtaaatataa acaagaagct aagtacgcct atctacacat tatctggtgg tgagaagcaa
     5461 agaatcgcct gtgcgagagt cttattgaag aatagcaaaa tcattttagc cgatgaaccg
     5521 actgggtcat tggataaaag aaataaggat aaagtagttg aaatcttatc gcaacaagct
     5581 tcccaaggta cgttagttat cgtagtcacg catgatccat atctgaccaa aataggaaac
     5641 aagaagatca tgctttaaaa atcaaaaagg aaaggatgtc gttttatgaa aaaagcagtt
     5701 attatttgtg cactagggat aggttttgtt ggaggaaacg ctatgtcatc tgaagtggaa
     5761 gcaaattcag ttcacggtga aatctattac aaatctttaa agccaggaga gattcatttt
     5821 gatgctaaag gtaatattat taagtcaaat ttaccagtag accgggaaat ttctagaaca
     5881 gcaattaatc atagctctgg aagatgggtt tattatagtg atacaacttg tacgagaaaa
     5941 acaggtcatt ctaaccacta tagtcgtgtc tataatcgtc acggtgcaaa agcgaaagtt
     6001 ggaaactcta ttcgatcagc aaatgcaaca aaaggagtat gggcctatgc aagtgcgaca
     6061 ggaaatagaa ctgacacatt ctcatgttgg tacaatccaa ccggttggta ttaagtatcc
     6121 aaaagtttat ataaaataga aaaaacatat aatgaaacag cgttaaaagt tatttttggt
     6181 agttttaata tattcatttt tagttgtata aaaatatatc ataataaaaa caacaaaaaa
     6241 atgtctggaa aatcgaacat aaaagtgtct gatttgaata tcccagcagc ggaagaagaa
     6301 aaacaaaatc gataacattt gttctaagaa ttagttacgt taaatacgga acgcaagata
     6361 gacttgaaaa acggtaacaa aagaagtagt atattaaggt gtgatgtgct acttgacatt
     6421 tattctgctg agcgaacttt ctggattgtg tagccttata tctattcagg acgtatcgag
     6481 cagattagta aaggtgttct tgatgatttt catcttgaac acctttgttt ttagcaattc
     6541 gcaaaaaacg aaaagtagga gaattgataa atgaaaaaaa gatttttagc acttgccatc
     6601 gtactaggca ctggcttatt gtcaggctgt acgaatgccg gtgaaaaaac agccgttagt
     6661 tataaaggcg gtacaatcag cgaacaagaa gtaatggata gcttgaaaaa aatgcaagga
     6721 gcagattccg ctgtgcaaca gttgatcgtt tatcaagtat ttgaagataa atatggagat
     6781 gacgtatcaa ccaaagaaat cgattctcaa tatgatcaaa caaagaaaca attgggtgat
     6841 tcatttgatt cacaattgaa atctgcaggt tacacagaac aaacattcaa agacagtatc
     6901 aaacaaagtc tagcctttca agaaggtcta aagaaacata tcaaattgac cgatgaagat
     6961 ttaaaaacgg cttgggaatc tttccatcca gaagtggaag ctcaaattat ccaagtagca
     7021 agtgaagatg atgcaaaaga tgtgaagaaa gctgctgata agggagacga tttctctaaa
     7081 ttagccaaag acaagtcaac tgatactacg acaaaagaag atggcggaaa agtgaaattt
     7141 gattccacta ctacaacggt tccggcagaa gtcaaagaag cagcctttaa gttgaaagat
     7201 ggtcaagttt ctgatgtgat cacttctacc aatgcttcaa cttatactac ggaatattat
     7261 gtggttaaaa tggtgaaaaa ccaaaacaaa ggcaacgaca tggataaata caaaaaagaa
     7321 ttgaaagaaa ttgcaacaga cacaaaatta agtgacagta ccttccagaa taaagtaatt
     7381 ggcgaagtat tgaaagacgc taatgtaaaa atcaaagaca aagactttga aaatgttttg
     7441 agtacattca cttcagattc tagtacagca agtagtaaat aagcggtata aataaaaaat
     7501 atgaactatt taaatcaata aaactgttca tctaaatctt tttattagaa ctaaatcaac
     7561 agtagtttaa ttactacttg atttagttct ttttatttta aaaatttttt ttacttagaa
     7621 tccagcgacc ctagatattt ttctgtataa tcttaaataa agaaaacaat atcaaaaaat
     7681 gcacgtagaa gtagataaat ggagtggttt tgcaaatttc ttttatttct agaagttatt
     7741 cacgtatacg gatttgtttt tctcacaaat aaaaaggcag gaagtacaat ggatcatttg
     7801 tatataaaat atattcatca attttccgtt ttggtgttag gcacactaat tatagcgggg
     7861 attgtcgcat ttattattca aggccgtgac atattaacag tacatcaaga gtttttcagt
     7921 tatgcatttg gtattcctct gatcgctata aggtctgata acaaaaagtg gaagaaacgc
     7981 tattacattc tcttgctatt tttgtgtttt tatctgccac ctaagatttt tactttatta
     8041 ggtatacaat gcctatcatt ttcttttatt tcctatatca ttgttttaat tttcctcagt
     8101 ttcatagtat ggatgtttta tcttgtcaaa aaataaatga atgtttcatg aacagtactt
     8161 catcacagcc taattttttt ctttatgcta tcgttatatt aaagaaatca atcagaaggg
     8221 aaagaaagtg atgaaaaaag ttttattagt ggtaaacccc agttcaggcg gtgaacaagc
     8281 aaaggaattt gagcaattag cgatagcaaa attggaatcg gtgtttgatg aagtggtcgt
     8341 cttgcataca aaaaaagcag gggatgcaaa aaactttact cgcgaagcgg ctacggaagg
     8401 gtatcatagt gtgtttgtca tgggcggaga tggaacagtc aacgaaggaa tcagtggaat
     8461 cgctgaacaa gaacatcggc caaatttcgg atttttccca ttgggtacgg tgaatgactt
     8521 ggctcgagca ttagggatac cgctagaacc tgaggaagcg atcaatcatt tttcgattga
     8581 atcagtcaag ccattggata ttggaaaaat aaatgacgac tattttatga atgtcgtcgc
     8641 aattggctct atccctgaat caatcaatga tgtagatgcg gagaagaaga cgaaatttgg
     8701 aaaactagct tatttcatgt caggaatcaa acagttagct tccacacaat cctactcgtt
     8761 tcacgtagaa gttgatggaa agaaggaaga aattgagagc agtaccttgc tgataggact
     8821 aactaactca gtcggcggtt ttgaaacatt acttccaaat gcaaaagtgg atgatggtaa
     8881 gctccatttg gtttatttaa aagattcttc tttgatcgat acgcttaaaa cattgccaga
     8941 cctattaaaa ggagtagatg aatctacgaa aaatctagcc taccttactt gtgagcaatt
     9001 agttgtgtca ttagctgatg aggaagaatt gacgacgaat gttgatggag atgaagggga
     9061 taaattacct gtgacaatca aagtattgcc ctcacattta caggtttatt gttaaaatgg
     9121 aggttgtgac cgaggagttg gcgggagaac accgcttgtt cgggataagg gactgtgaca
     9181 agacttttgt cacagccttt tttttgtaca aaaaagaaat ttacacctaa tagaaaaatt
     9241 tttccataaa aatacatatt ttaaatatga aagtacaatt ggaaatagat taaaacgata
     9301 aaataaaatt gtcaaaacgt cagagaggat ggtggagaat gaatcaatgt gtaaaaaagc
     9361 tgattgcgtc gattttgttt gtcttccctc tcttgatggt gacatccgtt tttgccgatg
     9421 tagagaaaac aaacgaatca acgcaatcag agaatcaaag ttttgacaag actacttttt
     9481 cagaagaatc gattacttct gaaactacag aatctcaaag tgaggcttct actaataaaa
     9541 ggcaagaaga aaataagaca agtgagacct cagaagtagc tgaacaaacg tctgatagca
     9601 gtgaagcggc actggcaaga gctgtttcag cggatgggta cagcgaagct gccacaacag
     9661 aagaactggc gcagcttctc gcagacgaat cagtaactaa gatccgactg attcagcctt
     9721 tgactttaga cagggaatta gagatcaaac gagatatcgt tattgatttt ggtggattcg
     9781 ctcacaattt cggcacacac catatttata tcaatgagat acctcagtcg atcgagttcc
     9841 agaattttaa aggaacagct gcacatccag gtggattgac accaaatatc gatggaaatg
     9901 ccattatcat tgcttatatg accgattttt ggggaagcag atatcatttt acgggagaaa
     9961 taaaatttac cgggacactt gatttgtatg atgggtccaa attaggactg atttacgctc
    10021 ctcgtgcaac tgtcacatta gatggtgttt ccggtgtgtt ggatgtccaa ccagtgaagg
    10081 aaggactgaa tgccgctccg ggtaaagcct atttttgtag aagctatcaa ttgaatgtga
    10141 tcaatggtag tcaactttat ggaccgtatc tagggaaatt ctacggtttt ctagattcag
    10201 gagatgagac tggtagtgga aaaacagcgc caggaatcca tatcttaagc ggttcaaagg
    10261 tctctcttga ttatgatcgg gcagatggcg ttagcgatga aggagaggca gtcgatacgc
    10321 tacctggtaa tgtcatgttt gaagtcagtg gttcgggaag cgaattttcg gtaaatacaa
    10381 agatcaatat taccaatgac aacaatcgcg gaatcatcca aatgagaggt tcaggatcga
    10441 aagtcactgt atcgaatggt gggaaaatca ccatcaatac agcaactacg ggcggatttc
    10501 gcttgcaagg agattctagt caaatccatg tatcaagtgg tggacaaatc tcggtcaaaa
    10561 tggctggaga tgacgatcaa cccgggaaca atgggatgcg ttttgtagga aaaggccttt
    10621 ctttgatcgt agaaggagcc ggatcagtta tcgacatcga taagcagagt gggcgttcca
    10681 gcgcagttcg ttttgagaat ggtacgcaaa agctgacagt aaccaatgga ggctcattga
    10741 gggtaagaaa tacaggtgat ggcaaatctt acgtgaacag actcaatcaa ggaaatcaag
    10801 cgatccaatt ttatgacgct tctggttttc tagaaagtcc aggttcagct gattttacag
    10861 tcactggaga aaaatcaaat atcgatatac gcgcagattc cggagcaact gtagatacaa
    10921 ctggagatat tgatttaaat tttacggcag gtgaaaaaac ttatttagtc atggtcggga
    10981 aaacagggga agataagacc ggcatcatca gtggggatgt gttgaatgtg gacttagaat
    11041 ctcctaccta ttttgatttc caaaacaaac ggattggaag cgagaccaat ggcataggcg
    11101 gctgggtatt ccaaggaaat ggagattctt ctttaaagat cgcccattca gaaatcgctt
    11161 tatggcgaaa aacaggcgca acattcgata actttgaaaa agacccggat tatttttctg
    11221 atatgacaga cttatcgatc aatgggaccg acttaggcaa tttcgtatca agccctagtg
    11281 caggtttaac aaatgaattt gctcagacag gtgccggaat gaaaaattat aatcgaatca
    11341 gtgccaataa tcagctcccg atgattgaat ccttaagagt gccaacgaat gcagataaaa
    11401 aaatctatgg gcatgtcgtt gttcccgaag gtgtcgaggc aaagccaaga gatgcttgga
    11461 caggcgaagt agaagtgact ttacgtatta cttacgcaga tacgacgaaa tcatctgtag
    11521 aaattactgc tctcacgcaa ggacaaacag atgaaaatga aggggcagga tataacccat
    11581 ggggagaagg cgaacaaggc ggcttgttcg aagttcaagt acccaatgat gagagattaa
    11641 aaacggagga tcaagtgcaa gttgttgctg ctaaaaaagt aagaggtggc caagaagtga
    11701 cagaactgga ctctgccaaa acgacagtcg atgtgattcc tcctgaacct gctaatttaa
    11761 gtaccacatt gatcaatgca gcttctcgca cgatcacagg tacaggtgaa gcaggagcct
    11821 tggtttcatt gaaaaaaaat caagctgttt tgtcagaaac aactattgat gatacagggg
    11881 aatttgttct ttctatccca gaaaatcaac tttttgcagg agatgtatta gaaattgtat
    11941 taaacgacca agcaggagaa gctactgcta agggtgtgca gaacaagcca agtaccaacg
    12001 atgaaattgg gaatcacaat ccaagtgata cgccagttgt ttatcatgat gccccgcctt
    12061 ttgcacctgc tacgaagatc gtagtagaag gtggtctctc atttcttgcc ccttccaaac
    12121 tcgattttgg tcagatcaaa gcaactggtt tgacacaaga agcatttggc caaatggata
    12181 tacaggaaaa attatggatt tatgatcagc gagaaacgaa aaatccgtgg atcttaacga
    12241 taaaattatc tcagcctttc acaaatgatg caggattttc tatgcaggat gtcctatatt
    12301 tcaagaaagg agaggagtat caattagtga atgaagaaga actggaaatt gtcagaggac
    12361 aaaattcaac gaatgtgcaa gcagattatt cagaatattt aaataacggt cgggcgttta
    12421 aacttgtctt aaccaaagaa aatcagatag ctggtaatta ctcagcagag ataacatgga
    12481 cattagcaga tgcgccgaca gaataaagat caaggaggat gattgatgaa tcgaatatgg
    12541 aataaaagtc atcgaaacaa ctgctcttta cttatgatcc ttctccttgg attcatcctt
    12601 tggcagacac ctgtccatgc ctccgaattc aattttgcgg tagattttga attaccggct
    12661 aatcagattg ataagaacaa aacatatata aatgtaagga tggagcctgg gaaaacacag
    12721 gaaatcccct acacggtctt taaccgaaca gataaatcag taacagttga gacattgatc
    12781 cactccgcta cgacgaattc aaacggtgtg atcgaatatg gagaatcaaa aagtaaattt
    12841 gatgaaacat taagttatga tatgaaaaac ttagcaaaaa cagtgggaga aataactgtt
    12901 cctcctcaaa gtgcggtcac tgagacactt tcactgaaag cgccagaaaa agagctggct
    12961 ggtgtggtcg caggagggat cacgtttcaa gaaaaaaaag agaacgtttc taacaaaagt
    13021 acagttggtg tcgtcaatca gttttctcaa gtgaaagcaa tcttgatttg aaatagcgaa
    13081 aaagagtctt ccccagattt gaaattaaaa aaagcttatg cggatcaaag cgatggaaga
    13141 aatgtgatta aggcgaatct tcaaaatcca aatgcttctt atatgttcgg cttgactaca
    13201 tcggttgaaa tctacaaaaa agaaacaaaa gagccttacc tttcaataaa aaaagaaaaa
    13261 atagatgtag cacccaatac aaattttgat ttacttgtcc cattagaagg aaaaaaatta
    13321 gctccgggac attatcaagc ggttgtgaag ggtgcttgga aagaaaaacg ctggaatctc
    13381 cataccgatt ttgaaataac tgatgatgca gcggaccaat tgaatgaaaa ggatattgat
    13441 ttaaaaaatc agccagaaac atttgactgg cgatggctga tacttgttgg agtcattctt
    13501 attggcttat ttgctggatt atttattt
//
LOCUS       DAJSMK010000067        13488 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.070, whole genome shotgun sequence.
ACCESSION   DAJSMK010000067 DAJSMK010000000
VERSION     DAJSMK010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.070"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(164..388)
                     /locus_tag="ON488_001926"
     CDS             complement(164..388)
                     /locus_tag="ON488_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HCR3232117.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="ON488_001927"
     CDS             complement(586..2166)
                     /locus_tag="ON488_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HCR3232118.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="ON488_001928"
     CDS             complement(2567..3943)
                     /locus_tag="ON488_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HCR3232119.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5189)
                     /locus_tag="ON488_001929"
     CDS             complement(4071..5189)
                     /locus_tag="ON488_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HCR3232120.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="ON488_001930"
     CDS             5331..5765
                     /locus_tag="ON488_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232121.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="ON488_001931"
     CDS             complement(5843..6376)
                     /locus_tag="ON488_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HCR3232122.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ON488_001932"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="ON488_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HCR3232123.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ON488_001933"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="ON488_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HCR3232124.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="ON488_001934"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="ON488_001934"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HCR3232125.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="ON488_001935"
     CDS             complement(10101..10679)
                     /locus_tag="ON488_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HCR3232126.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="ON488_001936"
     CDS             11001..11471
                     /locus_tag="ON488_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HCR3232127.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="ON488_001937"
     CDS             complement(11579..12805)
                     /locus_tag="ON488_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCR3232128.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3959 a         2719 c         2248 g         4562 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaa
//
LOCUS       DAJSMK010000068        13357 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.071, whole genome shotgun sequence.
ACCESSION   DAJSMK010000068 DAJSMK010000000
VERSION     DAJSMK010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.071"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            7..174
                     /locus_tag="ON488_001938"
     CDS             7..174
                     /locus_tag="ON488_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HCR3232129.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(236..2047)
                     /locus_tag="ON488_001939"
     CDS             complement(236..2047)
                     /locus_tag="ON488_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HCR3232130.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(2044..2409)
                     /locus_tag="ON488_001940"
     CDS             complement(2044..2409)
                     /locus_tag="ON488_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HCR3232131.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(2572..2967)
                     /locus_tag="ON488_001941"
     CDS             complement(2572..2967)
                     /locus_tag="ON488_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HCR3232132.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(2985..3947)
                     /locus_tag="ON488_001942"
     CDS             complement(2985..3947)
                     /locus_tag="ON488_001942"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HCR3232133.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(3947..4159)
                     /locus_tag="ON488_001943"
     CDS             complement(3947..4159)
                     /locus_tag="ON488_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HCR3232134.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(4180..4878)
                     /locus_tag="ON488_001944"
     CDS             complement(4180..4878)
                     /locus_tag="ON488_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HCR3232135.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(4898..5440)
                     /locus_tag="ON488_001945"
     CDS             complement(4898..5440)
                     /locus_tag="ON488_001945"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HCR3232136.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(5572..6576)
                     /locus_tag="ON488_001946"
     CDS             complement(5572..6576)
                     /locus_tag="ON488_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCR3232137.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(6573..7562)
                     /locus_tag="ON488_001947"
     CDS             complement(6573..7562)
                     /locus_tag="ON488_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HCR3232138.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVEKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(7559..8365)
                     /locus_tag="ON488_001948"
     CDS             complement(7559..8365)
                     /locus_tag="ON488_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232139.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            8531..9487
                     /locus_tag="ON488_001949"
     CDS             8531..9487
                     /locus_tag="ON488_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3232140.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATAANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(9564..10082)
                     /locus_tag="ON488_001950"
     CDS             complement(9564..10082)
                     /locus_tag="ON488_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCR3232141.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(10170..10319)
                     /gene="rpmG"
                     /locus_tag="ON488_001951"
     CDS             complement(10170..10319)
                     /gene="rpmG"
                     /locus_tag="ON488_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HCR3232142.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            10547..10993
                     /locus_tag="ON488_001952"
     CDS             10547..10993
                     /locus_tag="ON488_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HCR3232143.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(11188..13083)
                     /gene="asnB"
                     /locus_tag="ON488_001953"
     CDS             complement(11188..13083)
                     /gene="asnB"
                     /locus_tag="ON488_001953"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HCR3232144.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
BASE COUNT         4158 a         2832 c         2279 g         4088 t
ORIGIN      
        1 gattcaatga aaaaatttgt atctggaata ttagtaggaa gtctggcaac agccgctgcc
       61 gttgctggtt tggttgcttc tgtgaaaaaa acagtgatcg atccaattga cgaaaaagaa
      121 gcaatgatcg aagaaaaccg taaaaaagca atgcgtaaac gcgtttctcg ttaataatta
      181 tttaaaaata cgcatgaaga ctttctaaaa aacagataag tcatcatgcg tatttttatt
      241 tgtcagtcaa tataagttgt gctattttat ctgcctgtct cagattccat ggatctgtat
      301 aaggtctagc tactgctgca gttagccaat ccacaccttc aacaggtatt ccatagcaat
      361 aaaagtcaga ctggatttcc cctgaagcat caatcacgcg attcgtacct cgctcaacat
      421 ctatagcttc tgaatgataa cttcctgtat tatctgaaaa tgaaaaaggg cgaacaagtt
      481 tgttttcctt caaatttttt atgacaggat tacttgaacg agaaaagctt gtttgtggca
      541 atcgagcttc aatcaaatag cgactgctga tttctttatc ttgtagagaa ataacatagc
      601 ggttgtgctt ttgctgaata tcaaatggcg gttcgatcaa atgaaaaata cccgcatcta
      661 tcagtgctgc taattctttc gtccgaatga ttggcggacc gatcgttaaa aagctattta
      721 gatgagtaaa ccatccccat agtatttctt tgtattcctt agcagaaaaa acgtgccatt
      781 caatagcctg ccggattgga tcacgccagt cttttaatgc atcaaatgtt gaagcaaatg
      841 ctcctgtgca attgcctttt tccgcttctt ttatctgccc ttcaataaat attcggctag
      901 cttctgaaaa gggctcattc tgataggcaa gaggagtttc taaatacgac caatcccatc
      961 tataagggat tagtgctgga tgctttccga gacactcctc tgaagagagg gagagaaaat
     1021 catgctcaaa atttttcttt ggaatcggca agtgatattc ttcgatgatt ttcttgtaat
     1081 aaaacaactc aacgtctttt ttcagatagt caaaaaatgt ttcgccagtc aaaaatcccg
     1141 actgatgcca ttgctccagg ttttcttttg ttagtaaccg tggccatgcc attgctccgc
     1201 cttgcttttg atttcttcct cgagggtaat aagggagccc ccttcttgat ccactgtata
     1261 caatcggttc cttgcctgat ggatgataga ccagttttcc cttttcgttc tcgaagcgcc
     1321 ctcctcttga tactgtaaac aatccgacat aatcaaaaaa acttaagcct agacctctta
     1381 aaaagacatt ttctttaggc ggtatcttcg aaagatctac atctgcagga ttagaaggaa
     1441 gctgatacag taaaacattt ttctttgcgt agtctaccca cactctttct tcttctgtct
     1501 catcattttc ccagtgaccg cttgctaaaa caagctgatc gatagaatag ctttgctgat
     1561 ctgtctgtaa aagataacca tcttttcttt tgcttacttt ttttactaaa gaataaacaa
     1621 actgaataga agctggaaat tcttcttgca actttgagaa aaaccagcgt tgatagagtc
     1681 cgtataaaca tcgagtagat tgctgatctt tttccagacg attgatttct tctataatta
     1741 gttgcttatt tttggttacc gtctgttcga tataatctgt agcaggtcct ttactccatt
     1801 gaaacaagtt gggtccctgt gttaccaatc ctccactgga caatgtttca tctgtaaaaa
     1861 gcgtcacttg ttgagaaaca gaattcatta ataactccgg tggctgattc aaccgccaaa
     1921 ctcgacctcc aggaccattg ggatcgaaaa gaaaaagttc aagagaatgt ctgtcctgat
     1981 tattatggag aatcctttct gctacactta atcctctagg tccggcacca atgatcccta
     2041 ttttcatttg catgcctcca tttcgataaa ttttttcaat aaaacagcat ggttctgatg
     2101 ttcatttttt gcaccataaa caaaagtaat gactggatgt tctttcataa gttgactgag
     2161 tttaaaaata gcttgcttct tttcttcttc gaaaatcaat tcttgctggt atttctttgc
     2221 aaatgaagca aatcgttctg gtacatggtc aaaagttttg cgtgcttcat tactaggtgc
     2281 aatttctttc aaccacagat ctaactgcgc tttttctttt gaaattcctc gtggccagaa
     2341 tctatccacg agtattctat agccatcctc tttttcagca tcaaggtaaa cacgttttaa
     2401 tttgatcata gttgtttcct tctttctacc ttttcgctta gcttatatat gtagataata
     2461 gcacaaaata aaaaaaatga acggcacaac tatccattgc gccgttcatg tgatcttggt
     2521 caaaatctaa tgattgattc ggtttttaaa gctgtcatac aatcatctgt tttatacttt
     2581 tttacttttg atttttccag accatccgtc atatccaccc ttaagtaaat aaatctcttg
     2641 ataacctgct ttacgtaatt tatttgctgt acggatgctc aaacttttct tttgatcgta
     2701 aatatagaca ggctggtctt ttcgaataga tcctaatgaa tctttcaaaa cagtgtaagg
     2761 gatgtttctt gcacctaaaa tatgcccagc atcaaacaca tctttttcgc gaacatcgat
     2821 tacttgtgct tttctcattc cttctcgaaa ttcttcttct gtcaaagtcg ttgctgaacg
     2881 tttggccatt actcgtagat agacttccca aaggatgatt gcaagcacaa tcaatagcaa
     2941 aatgatatta attacccata aaaccatgta atgcctccgt ttttttaagc aaatttcaag
     3001 gctaatgagg cagcaccaat gacaccagct tcattaccaa gctctgctaa tttgattttt
     3061 gttgattctc ttacttgcgg gaaagtaaat tctttaaaat atttctctac acggctacgt
     3121 aaaaattctc ctgctgccga tactcctcca cctaacacga tacttgacgg atttaatgta
     3181 ttccccaagt ttccgcaagc taaacctaag tagaagcata cgcgatcaac aaccatcaat
     3241 gcaaacggat cgtcttcttg agccatttca aagatatctt tacttgttac ttcttctccg
     3301 ttgtctagca ttgctttcag ttttgaatcc cctgcgtatt cttctgccaa gaaacgacct
     3361 aggcgtacca cacctgtagc gctagataca gtttctaaac atccgcgttt accgcaagta
     3421 cattcgaacc cttcaggatc cacagtgata tgtccgattt ctcctccagc tccgctcacg
     3481 ccgtgaatca aatttccgcc agcaacgata cctccgccaa cacctgttcc tagagtaacg
     3541 aatacaacgt ctggatcgtt ttctccagca cctttccatc gttcacctaa agcagcaaca
     3601 ttcgcgtcat tatcgatagc gaatttgatt cctgttcctg cctcgatcag ttttttcaca
     3661 aattgaactt ctgtccagtt taagttatac gcaccaataa ccgttccagc ttcgctgtcc
     3721 acgcttcctg gggtacccat gccgattccg ataaagtctt cggctttcat attatataaa
     3781 ttcaaacgat gattgattga ttcaatgatt tcaggaacga tatgcttacc atcatccaaa
     3841 atattggtat cgatgctcca tttttgctga atctctcctt ctggtgttaa aattgcaaat
     3901 tttgctgttg ttccacctaa atcaatccca ataatcttct tgtccattac aaatttcctt
     3961 tctttcggct ttcttcaatt cggtgctctc tttttaatat gcgccacgct gtcatgtatg
     4021 tatcatgatc aatcaaacgg ctatcataca gattacgcaa ttcgatagtc attaattcaa
     4081 tgtcatagat gcgtgcaccc acatagataa agatgccaaa ttttttgaac agctgctgta
     4141 catcatataa gctctccatc tttaagcact tccttcatat tatacaagta aaccatattt
     4201 ttttaaaccc agtaaaatac atattacaaa aagaaataca aaaactagtg tagaaagaat
     4261 cctttggtgt atcgaatagc ttgtctgttg tttcggtaga cccaaaacat tccctaacac
     4321 taatccgcca attagcccac cgacatgtcc ccaaacatct acagaggtat ccagaagacc
     4381 aaaaacaaat gtcaacacaa taaataaaag aaaatgtctg actagctgct ggatcgctgg
     4441 gttatgttta aaatgaaacc ctaagataaa caacgcaccg aacaaaccga atatcgaagt
     4501 acttgcacca ccagacagaa cattcgcttc gttaaaagca aagcttgctg tatttcccat
     4561 tatcccgctg aacatataaa tcaagaaaaa acgccaatgg ccatagattg cctcgatttg
     4621 ctgccccata aaatacagta tcagtgagtt cattacgaaa tgcatcagtc caaaatggat
     4681 gaagattggt gtcactaaac gccaccattc attgaagtga acaagataag gaccatacat
     4741 tccggcataa taagggatct caagtcgcgg aaataattcc atcatgagga agaccgctgt
     4801 ctgtatccct aaaaaagcat aggtccataa cggtcgtctt aaccatgcac gcaattttat
     4861 ttgctgttga taattcatga aaacctccca tttcatttta gtcaataaac aattgttgga
     4921 tcttctgatc aaagctctcc ggttgccatt gttcattcaa ttgttcacga aaaacaaggc
     4981 tacatgtttt tttatgaaaa ttatttaaat accggtcgta ataaccaccg ccaaaaccga
     5041 ttcgataacc ggctctattg tagataatac ctggtacaat gaggagatcg atcatctccg
     5101 gcaaatagag cttctctgat tgtggctcaa gaacaccaaa actcgaacgt acaagaacgg
     5161 actgttcatc catttcataa aacgccatct gacgtttcgg caaagtttta ggtacaacta
     5221 ttttcttttg ttctttttct gctcgttgga taaccggctg tgtatccagt tcaaattcat
     5281 tcgataaagt cgtccctatc acttttgctg acttccagta ctcgctggcg aatagctgtt
     5341 tatagattcg ctgttctttt tcctttttct tgccactttt ggccagattt ttcagctttt
     5401 cgattccttt ccggcgtaat cttactttca attggtccaa aaactcaccc ttccttctct
     5461 cataaaatgg tataggaaaa aaagaaaaat agcaatcgaa ctttcaaata aatgcataaa
     5521 tagaataaaa agaagaccta gaaatgattg gccttccttt tttaatgaat ttcaactgtt
     5581 cagcgcgtgt ttttgtctga taaaaagtgc atacagaaaa tatggcgcac caaaaagggc
     5641 aatcaaaatt cctgtaggta cttccccact tggtagaatc actctagcaa ccatatctgc
     5701 actaagcaga aaaatggaac cgaacaaacc gctcagaaca aaggtccagt tattttcttt
     5761 acgtacgact agcttcgcag catgaggagc tagtagtcct acaaaagata aactacctgt
     5821 caccgctaca ctaccgcttg ccaaagcaac agctaacaac aaaaggattt tttgactttt
     5881 agccacgtta aggcctaatc cttgcgcgcg ttcttgacca aatgatagca atacaatcct
     5941 ctgtgcataa agtcctccta gcggaattaa gataaccgcc catggaagca atgcccaaac
     6001 ataaggccag ctcgcacccc agattgatcc cgctaaccat gcattcacaa atccataatt
     6061 ttccttagat aattggatcg tgcatagcaa tgttaatgca gaaaggccgg cattaacggc
     6121 aataccggac aataagattc gattcatacc caaaaagcca tttcgatcat aggccgcaag
     6181 atagacacag caagcagcta aaacaccacc tagaaaggct acaactagca atagaaacgg
     6241 cagcgaatag tgcgaaaaga aacctaaata aagcatcact aaaaatcctg ctccggcatt
     6301 aatgcccaat atactagaat ctgccaattc atttcttgtt actccttgca agatataacc
     6361 agaaacgcca agacaagctc ctgctaataa actgatcagt aatcgaggaa ctcgaaattc
     6421 tctaacaatc agcgccaaag aagatgattc tttccctatg aacgtggcaa aaagctgatc
     6481 caggtaaata aaaggcgtac caatcattaa actacctata gacaggatga caagtacaaa
     6541 aagcaagaaa tagaacgtcc aatatatttt tttcaccgtt gttccctcct tacttgtatc
     6601 agtaaaaacg gaacgccaat caatgcaatg actaatccaa aaggtgtttc aaaaggggga
     6661 ttgatcatcc tcgctgtaaa atccgccaac ataaccaatc caccgccaac taaaaaagag
     6721 acaggtagaa cataacgata gtccgttcca accattccgc gaacaactgg cggaaccaac
     6781 agcccaataa atgaaacagg tccgactaac gaaacggcaa tggctgctaa cactgcaact
     6841 agacagaaaa caatcaaccg cgttcgttta ggatgacttc caagagctaa tgcatgtgtt
     6901 tcactcaaat gaatcaaaga tattgctttt cctaatgaaa aagaaaccaa aacagcaagt
     6961 atatataaag gaaacaatac tgctaattgt ttccatgtga tattggcagc tccgcctaca
     7021 aaccaaaaag caagatcctg ctgcagatta aagaattggg taagtgcttg gctgatagca
     7081 gtaaaaaaag aactaatagc tacgccagct aaaatcagct gtaaaggatt catgcccatt
     7141 ttcgaaaact gcaaaaaacc aaatacgagc aaagttacag caaaagaacc tgccaatgac
     7201 attagaaaca cagaaaaatc agaagcttta ggccaaaaag caaaactaag ggccattgcc
     7261 aacgaagcac ccgcgttgat tcctagtaag cctgaatctg ctaaaggatt tcttgtcact
     7321 ccttgcatca atgcaccgct caatgcaaaa caactcccta caagaaatgc tcccgccaca
     7381 cgaggcaaac gaatatttcg tatgatttgg tgactttgtt ttgatctatc aaaatcaaac
     7441 aacgcctgcc aaaaatctgc tttttccaca gtcgctgcgc catttgaaag agcaacaaaa
     7501 aaaataatca aaagaacaaa acagaccaaa agcaggagtc tatttttctt catagtcctc
     7561 ataattgatc ctcctgctct tttggcaaca aatcataggt tagaaaaact ggtttatttg
     7621 ttcttggaag cgtgacaatc gttgcatcaa tctcaaatat ttttttcata cactcttttg
     7681 tgatcacttc ttcaggtgta ccttctgtga tcaacttacc gtttttcatt gctaataaat
     7741 aatctgaaaa acgtgaagca tgattaatgt catgaatcga catcaagatc gttgtttgtt
     7801 tcatttgatt gatttcagtc aataactgta ggatctctaa ttggtgtgcc ggatctaaaa
     7861 atgttgtcgg ttcatccaag atcaagatat ctgtttcctg agcaagcgcc atagcgatcc
     7921 agacacgctg ggtttgtcca ccagacagcg ttgcgatatc ccgcatacga aatccagcta
     7981 gacctgtagc atccaacgcc cactcaattg cttcatgatc ttgcgtgtcc atgccactga
     8041 acagtttttg ataagggtat cgtccgtaag atactacttc ttctactgtc atacctgtag
     8101 ggtgttcact agtttgtgct aataatgcaa ttttttttgc aagttctttt gaactgtatg
     8161 tagagatatc agagttattg acaatgatct ttcctgattt cacaggtagt atacgggtaa
     8221 aacttttcaa taaagtagat tttccacttc catttggccc aatcaaacta gtgattttcc
     8281 cttcaggaat cgtaacagac atgttttcaa tgattttttt gttttcgtag ccggctgcaa
     8341 tgtcagctgc tcttaatctc gtcatttcac ccatcctttc gctgaaaatc attctcaatt
     8401 atgacgctgt ttcaacattt cgtcaagcgc tactttcata tctatagcca aatgaagcgg
     8461 ttgacagcgt tcgaaatatc aggaataata accaatgaga aagattctca attatgttag
     8521 gaggaaagaa atgaaattaa aaacaaaagt attcacatta tctagcatat tgctgctggc
     8581 tggagtactg agcgcttgct ccccctcttc agataaagaa acagctacag ctgccaattc
     8641 gacgacttca tccaatagta ctcatacagt cacagataca cttggacata aagtagagat
     8701 tccaaacgcg cccaaacgga tcatcggcag ttacttagaa gactatctga ttgcactagg
     8761 ggaaaaacct atcgcccagt ggactgttgg cagtggttcc attcaagatt atctgcaaga
     8821 tgatttaaag gatgtcccaa cgatttctta tgaccttcct tatgagaaag tgttaagctt
     8881 tgagcctgat ttgctgttga tttcttcttc cgctactgtc gaaggcggga aatacgaaca
     8941 atatagcaaa atcgcgccaa cttatgttgt aaaaaacgga acagatgtca catgggaaga
     9001 acaactaaaa gatgtcggca aagctttggc aaaagaaaaa gaggcagaaa aaatcatttc
     9061 cgattatcaa aaatccatca agaaaactcg agaagaacta gcagataaaa tcgagaacaa
     9121 gacagctgca gtgttgtggg tgaccaacaa ctcagccttt atggtcagca aaaatcggtc
     9181 aagtggaaga atcgtatacg acgatctgga atttggtgtt cctgatctag tggaagaggt
     9241 ctccaaaaaa gccacttctg actggtctgc tgtttcctct gaaaagctag ctgaattaga
     9301 tgctgactac atcatccttg tgaacagtga caaagatgct gccatgttca atgaaccaag
     9361 ctggaagaat ctaaaagcag tgacagacaa tcatgtactg caattcggac ctgaatctag
     9421 ttggctatat aacggaccta ttgccagtca ggaaatggtc aatgatatca aagaaaaact
     9481 aaattgattt taactaaaaa aagcatcttc acgattagtc gtgagatgct ttttttctta
     9541 ttaacaaact agacgcatag attttattct tcttttgaag caaccctatt ttttactctt
     9601 tcccattttt gaaaacgatg ggcatataga ttttcttgat ccgttatccc ctcatactcc
     9661 tctataaggg cgaagtctga aaaatcaata ttcccaatat acgtatcgcc ttcaaacgtg
     9721 ctatcgatca atgttcgcca gatccgacca gtgtaaggaa gaagttcttg aaaaatccga
     9781 ctaccacccg aaacatagat atcttctgag atcgtttgac tatacgacaa aagttcatcg
     9841 atcgaatgca ttacttccgc attttctttc gtgcgaaaat ttggttgcgt tgtcaacacg
     9901 atgatatggc gataaggaag tgaaagatcc cccattcctt cataggtctt tcttcccatc
     9961 actaaaattc gatccattgt atgttcgcga aagaaacgca tatcatttgg caatcgccat
    10021 ggtaacaaac catttttgcc gatcagacca tttttatctt gtgcccacat ggaaataaac
    10081 atattatccg ctccttatga ttttagatgt tttgagataa aaaaagtctc aattctttga
    10141 ccagcaagga attgagaact ttaaaaacat tattttgttt cacggtgcaa agtaactttg
    10201 cgttcgcgtg ggcaatattt ttgtttttcc aaacgatcag gattgttacg tttgtttttg
    10261 cttgttagat agttacgttc tttacaagaa gtacactcta aagtgatgtt tacgcgcatg
    10321 tttttccctc ccatttttac aagaatcctc taagatgact ctcagacttg attatcttac
    10381 catgattttt tctagattgc tagtgttttt cacgattttg ttaagtaaaa ctacttgacg
    10441 ataaatacaa cggttttact tctcaaacaa aatctttttc tttttgtata aataccctta
    10501 cacttgttta tatagattat gttttttaat aaagggggat actaatatgc catggaacat
    10561 gaaggacttt cctgcatcaa tgaaaaactt agataaattg acaagaaaaa aagcaatcga
    10621 catcgcaaat gcattattag atgaagggta ccctgataac cgtgcgatcc caattgccat
    10681 tgatcaagca aaaaaatggt atgaagatgc tagtgaatca gaaaaacgaa ctttcgaaaa
    10741 agaaaaaaat ccaagcaaga cggatgaaca cgatacgaat cctcgtgctg gaaaactgct
    10801 tgattcagat gtgatcgtag aatatgagga agaacaatgg atcgtgaaat ctaaaggggc
    10861 aaaaaaggca agcaaccatt ttgatacaaa aaaagaagca atcgaaaaag gaaagcaagt
    10921 agcacaaaac aaagaatcaa ctttgttcat ttataaaaaa gatgggacaa aagaaaaaga
    10981 aatcgattat tgaacatatg taaaggggtt gtgacgaaaa tcgtgtcaca acccccttat
    11041 gttcgaaaca atggtgttcc tctgccaact ccgaaccata agtcataata tctataaaac
    11101 gggaagagct gttttttgaa attgtttctt atcactcagt gttaaacggt aggagaaaac
    11161 ctctttttta ttgatatttg attttcatca aacagtcaca tagtcgattg cttctgcttg
    11221 cggaatcgtt tcatctacaa agtagacttt ataccatgtc aagaaactga agattgtcca
    11281 gatttttctt tgctcttctt tacgtccttc gtgatggtca tctagcaact tcatgatttt
    11341 ttcttgatca aaaaattctt ttgcaaaatc tgcttcgaat aatgctttga cttgttcgta
    11401 gccgtgttct tctttcaacc aagctttgat tggcacaggg aatcctaatt tcacacgatt
    11461 cgaccattct tccggaagat gtttgttcgc agcttgtctg aaaatatctt ttgtgttgtt
    11521 ttgattcaat aaaaacttac ttggtatttg ttgagccaat ttcatgactt cgatatccaa
    11581 taaaggtact cggacttcca aagaacttgc catagaaagt ttatctgcct ttaacaagat
    11641 atcttttggc atccattgat gaagatcgac atattgcatc ttattgactt catctttgat
    11701 tccttctgtt ttctcgtaat gaacagtcat gatttcatcc acagatggtg ctgtttgata
    11761 ttttggtgtt aacacttctg atgcttctga ttcttcgaac actcgagcat gaccgataaa
    11821 atattctttt gcaggagcaa gtgattcata taaatggatc cgtccatgga agtttttcat
    11881 ttttccgatt ttacgtccta aattatagcg tgttcctttt ggtaattttt tcaatccttg
    11941 agcaatcaca cggatgaatt ttgaattcgt atggaatcca tacgtttggt atcccgcaaa
    12001 cagttcatcc gccccttctc cagattggac tacccgcaca ctttgtgaag caagatttgc
    12061 taaaaagtac aaaggtacgc aagaaggatt tgaatcaggt tcatctaagt gatactggat
    12121 caaagggaat gctttgaacg acatgtctcc gtcgatcact gctgctgtat tatctaagtc
    12181 caatagttcg gttagttttc tggcttcaat cgcttcatta taggttttat catcaaaccc
    12241 gattgagaaa gaatgatctg gtttcaatac agaggttaca taactggaat caaccccgct
    12301 ggataagaaa gaaccaactt ctacatcact gaccgtatgt gcttcaatag aagcttgaac
    12361 ggtttcgtcg attttttcga tccattcttg tcgggaatgc gtttcttttg tttcaaaatc
    12421 tgcatcccaa tattgctgaa tgtctatttt tccatcttta tacgtataat aatggccttc
    12481 aggcaaacga tagacatctt tgaagaatgt ttcgccgttt aatggagaat attggaaagt
    12541 catataaggt ttcaacgctt ctttgttcaa ttctttgtta aaatcaggat gaggcagaaa
    12601 acttttgatt tctgaaccaa acataaatgt tccgttcatt tctgcataat aatatggttt
    12661 gatcccaaag tggtctcttg caccgaataa ctcattcttt tcattatccc aaatagcaaa
    12721 agcaaacatt ccgcggatct tttgcaataa ttctgttccc cattcttcgt aaccatgcaa
    12781 aaggacttct gtatctgcat gtgtttgaaa aacgtggcca gctgcaatca attcttctct
    12841 caaaggctgg taattataga tttcgccatt aaaaataatg atctttgtcc gatcttcatt
    12901 gtaaataggc tgagtaccgc cctctaagtc aataatactt aatcttctga atcctaaagc
    12961 aacatgttta tcgatatatt ctcctgaact attaggtcca cggtgaacga ttcgatccat
    13021 cattgtatta ataattgttt ttttgttgtc cttgtcgtta acaaaaccta caataccgca
    13081 catttaactt tcacatccta atataaaatt actgtttatt tcattcatat gcatcttatc
    13141 atagaataaa tagcggacga atattttctc tcttacaatt tcgtcacgtg aaaacaaaag
    13201 atgaaagttt ctgtttttac agaaaataaa gtcccaatat ctaatttacc atgttttctt
    13261 ttttgaggct accttattct cttcgtgtta aaaaaatatt agtggatgct atttccaaaa
    13321 aaaccagcaa aaaaagacac gacctaaaga tcgtgtc
//
LOCUS       DAJSMK010000069        13149 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.072, whole genome shotgun sequence.
ACCESSION   DAJSMK010000069 DAJSMK010000000
VERSION     DAJSMK010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13149
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.072"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(80..152)
                     /locus_tag="ON488_001954"
     tRNA            complement(80..152)
                     /locus_tag="ON488_001954"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(117..119),aa:Lys,seq:ctt)
     gene            533..1102
                     /locus_tag="ON488_001955"
     CDS             533..1102
                     /locus_tag="ON488_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HCR3232145.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1089..1949
                     /locus_tag="ON488_001956"
     CDS             1089..1949
                     /locus_tag="ON488_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HCR3232146.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2139..2843
                     /locus_tag="ON488_001957"
     CDS             2139..2843
                     /locus_tag="ON488_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3232147.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2848..4683
                     /gene="walK"
                     /locus_tag="ON488_001958"
     CDS             2848..4683
                     /gene="walK"
                     /locus_tag="ON488_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HCR3232148.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4680..5996
                     /locus_tag="ON488_001959"
     CDS             4680..5996
                     /locus_tag="ON488_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232149.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5997..6866
                     /locus_tag="ON488_001960"
     CDS             5997..6866
                     /locus_tag="ON488_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HCR3232150.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6921..7730
                     /locus_tag="ON488_001961"
     CDS             6921..7730
                     /locus_tag="ON488_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR3232151.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7833..8462)
                     /locus_tag="ON488_001962"
     CDS             complement(7833..8462)
                     /locus_tag="ON488_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HCR3232152.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8632..9924
                     /locus_tag="ON488_001963"
     CDS             8632..9924
                     /locus_tag="ON488_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3232153.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(10000..10662)
                     /locus_tag="ON488_001964"
     CDS             complement(10000..10662)
                     /locus_tag="ON488_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HCR3232154.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10887..11171
                     /gene="groES"
                     /locus_tag="ON488_001965"
     CDS             10887..11171
                     /gene="groES"
                     /locus_tag="ON488_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HCR3232155.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11222..12847
                     /gene="groL"
                     /locus_tag="ON488_001966"
     CDS             11222..12847
                     /gene="groL"
                     /locus_tag="ON488_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HCR3232156.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLAQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4371 a         2265 c         2834 g         3679 t
ORIGIN      
        1 aaataaaaaa agaacagcgt aaatgttttc gaaatgcttt cgcaccaaca tttacctgtt
       61 ccgtgggttt ggcacccaat gggccgtgag gggctcgaac ccgcgacccg ctgattaaga
      121 gtcagctgct ctaccaactg agctaacggc ccgtacaaaa agtacttaat aatagtagca
      181 ctaagaattt taaaatgcaa gactacattt aaagaaaatc agaaaaatct ttacttcctt
      241 ataggaaatc attcatagat tattcacatt tgctcgctat tatataagca taccaacaaa
      301 caaagttctt gcaagagaac aaaccctaac acttttttca ttttttactc ctttcccgcc
      361 gtctccccgg cgggtctcct gttcttaacg ataaaagaca agaaggctta gccttcttgt
      421 tttttgtttt catggaatcc cgctaatcaa atcacctagt taaagcaact agattgaatg
      481 tttatcataa gtctgatatc atgtttatga aatgaaaaaa ggagcggtta tgatggaaaa
      541 aatgcgtcag caattaatgg agtgggggaa ggaactagaa acattccgtc tgcctcactg
      601 ggaagaactc cctgacttag aactttatat ggaccaagtc agaacgttag ttgatcgtta
      661 tctttcacct gtgatacaag gagaaaagca tccattgctt acctcttcta tggtaaacaa
      721 ttacgttaaa ctaggtttga taccagcacc agttaaaaaa agatataaca aagaacacgt
      781 agcattttta cttgcaatca ctacgttgaa acaagtattg actattcctg aaatcaaaga
      841 agggatattg ttccaaggaa aaacagtagg aattcgtgaa gcctataatc tattttgcga
      901 tgaacaagaa gcagctgtgt ggatggtcag ccaattagca caaggtaaat ctcatccgca
      961 aaaattcgac caggcaaccc ctgtagaata tattgctgta agagcggcaa ctttatcgtt
     1021 tgcaatgaaa cttcttgcgg aaaaaacgat tgttctagaa accgaatatt taaaagagga
     1081 gaaaacaaat gaaaaacaat aaaatcgcaa ttttagtaga ttcaggtacg gatgtgccag
     1141 aagaattgat aaaaaaatac gagatgtata tgatcccatt gaaaattatt tataaagatc
     1201 aggtatatac agataaaatt gacattacct ctgaagagat ctatcaacgt ttgccagagg
     1261 aaatccctgg tacatctttg ccggatggtg agtcgatcac agaaatcttt gagcaaatca
     1321 aaaaagacgg ttatgaaaag gtacttgcgg taacaatttc cagtggattg agcgggacat
     1381 ataatgtggt tcgtttaatt gcacaacagc aagaagaatt ggaagcatat gtactagata
     1441 cgaaaaatat tggtattggt gcaggttttt ctgcgatcca agcagcaaaa tggctggaag
     1501 aaggagtaga atgggatcaa ctgatcagta atctgaatga gttagtcgaa agaacaaaag
     1561 ttttctttaa tgttgcgaca ttggaatatc ttcaaaaagg tggacggatc ggtttagttg
     1621 cttctattgt aggaaccgct ttaaagctta acccaatcat ctcatgtaat gaagaaggga
     1681 tttattacac agtaggaaaa gctaggggac gtaaaaaaag tttggataaa acggttgctt
     1741 acgtcaaaga aaaaatcggt aatgcaaagg tcttcaactt agctgttgcc catggggatg
     1801 cgaaagaaga agcaattgaa atggaagcga gacttaaaag agagttccca caagcaaacc
     1861 aaatctactt tggccagatt tctccggcat tagtagtcca cactggtccg ggattattgg
     1921 gtgtcggtgt acaagtttta gaaggataaa tcaaaaaaag gaaacactga ggtgaaaatc
     1981 agtgttttcc ttttttattg aagttagaac aaaaaataat aaagtatttt gcactttcat
     2041 tttaattttc tcttttgttt tataggcaaa gatgaaacaa aagcagaaat acggtataat
     2101 gagaaggtat gacaataata tataagaggt ggctctttat gaaaaaagtt ttagttgtcg
     2161 atgatgagaa gccgatttcg gatatcgtca aattcaattt agccaaagaa ggctatgatg
     2221 tttatactgc atatgatggg gaagaagcct tggaaaaagt tgctgaggta gaacctgatt
     2281 tgattttact tgatttgatg ctacctaaaa tggacggctt agaagttgct cgtgaggtac
     2341 gcaaaactta tgatatgccg atcattatgg taacagccaa agattctgaa attgataaag
     2401 tcctaggctt agagttaggc gccgatgatt acgtgaccaa gccattttcc aaccgagaat
     2461 tagttgcacg tgtcaaagca aatcttcgtc gcggtgccac ggctgcgaag gaaccagaag
     2521 aggcagcacc tgcggaattg acgattggtg atttgacgat ccatccagaa gcttacatgg
     2581 tgacgaaacg aggagaaaca atcgagttaa cacatcgtga attcgaacta ctcttttact
     2641 tggcgaagca ccttggacaa gtgatgacaa gagaacattt attacaaacg gtttggggtt
     2701 atgattattt tggagatgta cgaacagtgg atgtaactgt acgtcgtttg cgtgaaaaga
     2761 tcgaagataa tccaagccat ccaaattatt tagtgacacg tcgtggtgtc ggttactatt
     2821 tgcgtaaccc agaacaggag taattggatg aaaagaaaag tccgcttttt tcgatcagtc
     2881 aattttaaga tcgctattac ctttattctg attttattga tctcgatcga aattattggt
     2941 gcctacttta tacgtggttt agaacgttcc acgatcaata catttattaa agatatgaat
     3001 caaacggtgg aatcattagc aacaacaatc agcccggaat tgaatcgaaa agataatgca
     3061 gatgatgaag aggtaaatgc gaatatcaaa agatttattg aaaacagtgc gactagcgat
     3121 atcatcgaaa tacgggtcgt tgacgaaaaa gggatcatcc gaggaacaac cgatgtcaat
     3181 gaacaaagcg ctgtgggaaa gaaaaatgat tatgttgata tcaatgattt cacgactaaa
     3241 cgttatgttg ctttagataa cgacgataaa cgggtgaata tcaatgttca accgatcctg
     3301 tccccgaccg gcgatgccgt tatcggggct ctttacgtca aaagtaatat cgaacaaaaa
     3361 tattcggaaa tcaataacac agcagtcatt ttctttactg cctcactaat tgcggcattt
     3421 atttcaatga tcgtatctgt tttagttgct cgttcgatta cacagccgat cggtgaaatg
     3481 agagaacaag ccattcgaat cgctagagga gactacagtc ggaaagtcaa agtgcatgga
     3541 caagatgaac ttggacagct ggctgatacc ttcaatcagt tagctgaacg tattgaagaa
     3601 gctcaagata caatggaagc tgaacgcaat cgtttggata gcgtgctatc ccatatgaca
     3661 gacggcgtca ttgcgacaga tcgcaggggt aaagtcatta cgatcaatga tatggctgtt
     3721 tccttgctag atatcaaaaa cgaggaagca atcggacaat cgattttgac acttttagat
     3781 atcgaagaag aatatacgtt gcggaaatta ttagaagatc caaacgaaat ggtacttgac
     3841 cgttcaacca gtacattgga aagtgatcag atgatcttgc gagtagactt ttctatgatc
     3901 cgtcgcgaat caggttttat cagcggatta gtagctgtct tgcatgatgt gacagaacaa
     3961 gaaaaaacag aacgggaacg tcgtgaattc gtctctaatg tttcccatga acttcgtaca
     4021 ccgttgacaa gtatgcgtag ttatatcgaa gcattgagcg aaggtgcgtg gaaagacgag
     4081 gaagtagcac caaatttttt gaaggtaacg ctagatgaaa cagaccgaat gattcgaatg
     4141 atcaatgacc tcttaaatct atctcgcatg gatacaggta atacccagct tcaattagaa
     4201 tatgtcaatt tcaacgagtt agtgaatttt gttcttgacc ggtttgatat gatggtggga
     4261 aatcaggaaa aaaattataa gatccgtcgt gaatttacgc aaagagatct ttgggtcgaa
     4321 gtagatacag ataaaatcat ccaagtagtc gataatatca tgaataacgc gatcaagtat
     4381 tcaccagatg ggggaacgat tacttgtcgc ttattagaaa cgcataataa cgtggtttta
     4441 agtatcaccg atcaaggatt ggggattcct aaaaaagatc tgaaccgagt gttcgagcgg
     4501 ttctatcgag tagataaagc acgtgcaaga gcacaaggtg ggacaggact tggattagct
     4561 atttctagag aagtgattaa ggcgcatcga ggcgctattt gggcagagag caaggaagga
     4621 aaagggtcga ctttttatat ctcgctgcca tatgaacctt atgaggagga atggtgggaa
     4681 tgagaatctc tgaaaaagtc gttcgtatag gactcatttt gatggttgcg ttaagcatat
     4741 acttctctta tgcaatctgg ctgagcccag caggaaaaag ttcaatcaac gtagatgaga
     4801 caaacactca aatgatcgag tctcaaagca atcgaaaaac ttccgaagtc tttcttccgc
     4861 ttcatgttac atggcaccat tcgggaatga tccaagaaac caacagtgaa aatctcgtgt
     4921 accgattgca attgatcatc gataaagcaa gatttggaaa gctttctgaa gtagtttcag
     4981 gagacaaatc acagtttgaa caggtgaaaa atctgaactc tggttttgag ttggcctata
     5041 atgcgccttt tttgctaaga gaatacaagg aagcatttga tttagattta gatgtgtcga
     5101 acttggcaaa agaaagcgaa aatatgtatt ttactagaat acaattcgat caaggaaata
     5161 aaaaaatccg atttttgaat tattcgaacc atctcgtata tgaagcaaat atttcgttga
     5221 attggacaga tatcaataaa gaattaacag caaaagacac aaaatggaca gaaatgacaa
     5281 cagaaccatc gacgatcgac acgcaatatg ctacgaaaca ttcgatcaaa ctgaaaaagt
     5341 atagttatat cctgtcacag caaccctata cactttttag aaatgctttt ttccagaaac
     5401 cagatagcgt gaaaaataat gatgaaagca atgaattgat tttttacggt gggaatgaaa
     5461 caatgtctat ccattcggaa acgcaagtag ttgattttcg tggagagctg ccagagaaaa
     5521 aagaaaatgc tagtgtattt tctgaaagtt tcccctatat tagcaaatta ggcagttctt
     5581 tagggaacct cagatatttt gaccgcagtg acaatacgat cgattatcgg atattcgtgg
     5641 aaggcttccc ggtttttggg acagacagca gaggacagat tggtgtggaa gttggcggtg
     5701 aaacgaatgg ttctgtgcaa gtgaatatcc aaaccagttt gaatacgatt caagtgccga
     5761 taccttcaga cgaagaagta gaacttgcaa gtacgaatga aatcatccag cagttaaaag
     5821 ctaagggagc agatagcaac aagattggtt cagtgatcgt tggctataca tggcaaaatg
     5881 tcaaagaaac gaatcgtgtc gttgatctct tacctgaatg gtatgtgaaa tataaagata
     5941 actggtattc agctaacgac cttctggaaa aattacctgg attggaggcg aattaattgg
     6001 atttcaaaaa aatcgaatgg atatttttcg tcgctttttt agggttgaat gtgtttttat
     6061 tcagcagtta tcatgacgcg gtataccaag aaaacaatgt cattcgctct aatcagactg
     6121 aatcaatcca acaacgtctg gctagcgacg atatcactta cacggggaag atttcgtctg
     6181 agaacaagca aggctattat cttagcgcgg agcagaccaa tcttagcact tcattagcga
     6241 attatcgcaa ggctggtaaa agcggcttgc tggcaagtgg tgtgttttta gacggtgatg
     6301 ttttgacgaa atctttatcc agttcagatg ctgaaaagaa cgtgatcgat ccagataaaa
     6361 ttagtagttc cttggaagat tttttatcta acaaagacaa tattttattc ggtaatgatt
     6421 atgtgtacac gaaaaacttt tctcatttag aagaagaacc actagaaatc caagcaagcc
     6481 aagagtatga aggcatccca ttcaatgatg atacagcaaa aatcgttctt tctttagaaa
     6541 aaaacgataa tgattatagc atcacgaaat acatgcagac gcatttatct gatatcgagc
     6601 agctgcgcga aaagacggaa ctgtatacgg aagaggaagc aatcaataca ttgtacatca
     6661 ataacaaaat accaagagga tcaaaaattt tatggcgtca gctagcttat tcctgtattc
     6721 tgaaagtccg ggaaaaaaat gtgtatgttc ctgtttggca tgtagcgatc gaaacaagcg
     6781 ataaagtggt ccaaattgag agtgtcaacg ctttcagcaa tacgatcgtg acaaacaata
     6841 ctgtaccaaa agtggaagat caataaaaaa gcgagtataa tgaaaaaagt ttacaaagta
     6901 agaagggaag taggagtcaa atggctgaag aaaaaccagc ttttaaaatc agtatcctag
     6961 caagtggaag ttcgggtaat tcactttata tcgaaagtga aaaaaaacgg cttttggtcg
     7021 atgcaggact tagcggtaaa aaaatcactt ccttgatggc tcaaattgat cggacaccgg
     7081 accaattaga tggaatactt gtgacgcatg aacatcgaga tcatatacat ggcgtgggtg
     7141 tcttggctcg taagtatcat ttggatgttt ttgccaatca gcagacttgg gaagcgatgg
     7201 aaccactgat tggaaatgta ccagtggaac aaaaacatct atttgagatg gggaaagtca
     7261 gaacattcgg cgatatcgat attgagagtt tcggcgtctc ccatgacgca gcggctccgc
     7321 aattttatcg tttccataaa gaaaatcggt cattcgtcat gttgacggac accggatatt
     7381 gcagtgatta tatgcgaggt gtcattgaaa atgccgatgg ttatttgatg gaaagtaatc
     7441 atgatcttga gatgttacgc atgggacctt atccgtggaa tttaaaacag cgtattttag
     7501 gagatagagg acatctttcc aacgaagacg gtgcacttgt catgactgat gtgatcggta
     7561 atcggaccaa acgaatctat cttggccatc ttagcaagga aaacaatatg aaagaacttg
     7621 ctcatttaac aatggaaaat gttttgaaag aaaaagattt tggcgttgga catgattttg
     7681 aaatctatga tacagatcca gatgaagcaa ctgagctatt ttcgatttaa acagttcaat
     7741 caataaaaat ataaaaagca gaagataaaa tcaatcaggg ttggttttat cttctatttt
     7801 tattttttta gcatattaaa aaaataaccg tattatcgac tgactacact gatgtgctgc
     7861 ttttcatgtt tctcatccag tatctcatct actaatgcaa tcgcgtaatc tgccatgctg
     7921 atcgtactgt cgccagcagc gtttctttgt aaataatcat cacttaacaa ataagtacct
     7981 gtacgtttgc catgtggatc aaataaagaa gctggactga tataagtcca atgtagattt
     8041 ttagattgtt tcaattttaa caatccttcg tacatattga aagctgttgg atagaagggt
     8101 gcatttttag gtacttggtc aatcatacga gtcgtctttt ctgtatctaa gaataacgaa
     8161 gaggcacccc caacgacaat taagcgtgta tcggttcctt caagcatctc aatcaaatgg
     8221 gacaaagaag tttgatgcat ttcttctttt cctttgggag cgttgaaagc atcaacgaca
     8281 acatcaaaag atgcaagatc agtagttgtc aactcaaata aatccttttg tataaacgga
     8341 acatctgatg gcaatttttc tggatgacgc acgattgccg tcacgtctaa atctctggac
     8401 aatgcttcgt ctaaaataaa tgaacctgca tggccagtag ctccaatgag tgcaattttc
     8461 ataaaaaacc tcctttttta ttcctgtcca ttgtaagcag ttgctgaata ttcgtcaaag
     8521 aatccgattt ttgaaaagct cagtgcgcat tcctttcatg gttcgtgatc attgggtata
     8581 gttaaattaa gaaaactgat tgataaaaat agaagttgaa ggagataaga aatgaaagag
     8641 tggttagatc gtgccttttt accaatgata acatctgttg tgaatcttag acccttaact
     8701 gctttgcgta atggaatgac ttacacgatc ccaataatta ttgttggctc gctgtttttc
     8761 ttatttgctc attttcctgt ggattacatc gctcagtgga tagacaaaac aggattttct
     8821 atgtatttta cacaagtata ccaggctaca tttgatgtga tagccttttg gatcgttttt
     8881 gccattgcat acgcttatgc aaaagaagaa gacatcgatc gcttaccagt cggcataaca
     8941 gccttgtctg cttatctact gcttattcag ccactaaata ctcagataga tactgtctgg
     9001 acaggtgctg aagggatact aggagcagtt acaactgggc tcatcatcgg atggggctat
     9061 gcacgtttag taagacttgc gaaagggtgg aagcaaagag agaagatacc tgaaaatgtt
     9121 tggcagtctt ttacttcatt gattccaatc attgttatag tcacttttac gcttatcggt
     9181 tcagcggttt ttcaacagtt gttcagaatg actgttgttc aaggagtatg gacatatgtc
     9241 cagcttccca ttcaatcgtt catagacacg ttgtttggtg tgcttttatt aggttttttt
     9301 gttccgtttt tatggttatt tggtcttcat ggatctgcga tggtcaatgg gttggttagt
     9361 cccgtcttgc aagcgaattc attagcgaat gcagaaatct tagcctcagg acaagagttg
     9421 acggtggcaa atggcggaca tatcgttact cagcaatttc tcgatcagtt catgacggtt
     9481 acgggtgctg gattgacgtt aggggctgta ttttttatga cggtttttgc gaaatcgaag
     9541 aaatacagag aattaggaaa tcttgctctt ttaccagcct ttttcaacat caatgaatca
     9601 attatttttt ccacaccgat cgtgatgaac ccgatgatgg ctgttccttt tattttcgca
     9661 ccggtcgttt caggattgat tacctattcc gctttatatt ttggattcgt tcctttattt
     9721 acagcagtcc aagtcccttg gacaacaccg ccgatcctct cgggtttctt agtaggcgga
     9781 gtgcctgcag cgattttaca aggtatcgtg ttgtcaatta gttttttcat ttatttccca
     9841 tttttgaaaa aaatagattc tgcaaactgc aaaaaggaaa gacagacaaa aaatgatgga
     9901 gcagcagaaa agatgaacga ctaaaaaaca aaaatactcc tgtcgcttta gattgggaaa
     9961 atcaccaatc taggatgaca ggagtattta tagtcatgtt tatactagcc ctttttggac
    10021 agctaattga acaagaacaa ctaatgtgtt cattcctacg tgtgtgatca tcgatgtcca
    10081 gatccgacca gttgctttgt actctaggct gaagaagaaa cctaggaaaa agtagattag
    10141 cagatgacca tcattatgag caaacgcaaa cagcaaagag ctgatcactg ctccgaccca
    10201 aaaatttgaa tatcgactga tgatccccag tatactgcgg cggaatacga actcttccat
    10261 gatgggtcca gcaacagttg tcgccaaaat aaaagcgggt gcttccatga tcatctggat
    10321 gatattttgt gtattctcgg aaggggttgc tttgccaaac aatacagatt ctaacatgac
    10381 agcgatgctt tgcagaatca atgcgacaaa gattccaacc aatccataaa taacaatctt
    10441 tggagcagaa gcttttttta ccgctgattc gatcgctaag ggttcacgtt gcttaaaata
    10501 aaaaatagct aggacaacgg cgcctagtat atacatgact gcagttgctg tgatcaattc
    10561 agacgtagat tttacaagtc ctatcgaagc taggatcaag ggtgagataa aaattagacc
    10621 atagcaaaaa atgctgagga agctatattt ttttaaagac atgtaattcc tccttttaag
    10681 ggataacaag catgcaaggc aagcttatat cgattgattt caattatatc ataatttcaa
    10741 taagcagctg tcagaataaa atttcttttc tttgatttaa aagcttgcaa aaaagaggga
    10801 gaatgagtat tattaaaaat gtaggttagc actcgaaggt taagagtgct aacagattaa
    10861 aaaaagagtt atcggaggga tttatcgtgt taaaaccatt aggtgatcgc gtcattatcg
    10921 aagtcgcaaa agaagaagaa aaaactgtcg gaggaatcgt tttagcttct gctgctaaag
    10981 agaaacccca aactgggaca gttgttgcag tcggtgaagg ccgtttgtta gaaaacggtg
    11041 aaaaagttcc tgccgctgta aaagcaggcg accaagttat gttcgaaaaa tacgccggta
    11101 cagaagtaaa atacgaagga aaagaatatc tgatcgtcgc aggaaaagat atcatggcga
    11161 ttgttgagta aatttggaag ataaaaaaat aatcaaaaat aatcaatgag gtgaatcaat
    11221 catggcaaaa gaattgaaat ttgcagaaga cgcacgcgca gctatgttac gcggggtaga
    11281 taaattagca gatacagtga aagtaacatt aggacctaaa ggccgaaatg tcgtactaga
    11341 aaaatcttac ggctctccat tgatcacaaa tgatggtgtg acgatcgcaa aagaaatcga
    11401 attagaagat cattttgaaa acatgggtgc aaaacttgta tcagaagtag catcaaaaac
    11461 aaatgatatt gcaggagacg gtacaacgac agcaactgtt ctggcacaag caatcgttcg
    11521 cgaaggttta aaaaacgtaa ctgcaggtgc taatcctcta ggcattcgtc gcgggatcga
    11581 attggcaaca aaagcagcag tcgaagaatt gcataatatc tcaactgttg ttgattcaaa
    11641 agaagccatt gcacaagtag cagctgtttc ttcgggttct gataaagttg gacatttgat
    11701 tgctgatgca atggaaaaag ttggaaacga cggtgtcatc acaatcgaag aatcaaaagg
    11761 gatcgaaaca gaactagatg ttgtagaagg tatgcagttt gatcgtggtt acttatcaca
    11821 atatatggta acagataacg acaaaatgga agctgttcta gaaaacccat atatcttgat
    11881 cacagacaaa aaaatctcta acatccaaga tattctgcca ttgttagaac aaatcttgca
    11941 acaatcacgt ccattgttga ttattgctga cgatgtagat ggtgaagcat tgccaactct
    12001 tgtattgaac aaaatccgtg gaacattcaa cgtagtagct gtaaaagctc ctggtttcgg
    12061 cgatcgtcgt aaagcaatgc ttgaagatat cgctattttg acaggtggta cagtaattac
    12121 tgacgatcta ggtttagaat tgaaagatgt aacaatcgaa aacttaggaa atgcttctaa
    12181 agttgttgta gataaagaca atacaacgat cgtagaaggt tctggagaaa aagaagcaat
    12241 cgaagctcgt gtgcaattga tcaaaaacca aattgctgaa acaacttctg attttgaccg
    12301 cgaaaaatta caagaacgct tagctaaatt agcaggtggt gtagctgttg ttaaagttgg
    12361 tgcagctact gaaacagaat tgaaagaatt aaaattacgc attgaagatg cattgaatgc
    12421 tacacgtgcc gcagtagaag aaggaatggt ctcaggtggt ggtacagctc tagtgaacgt
    12481 tatcagcaaa gtttctgctg tagaagcaga aggagacgtg gcaacaggta tcaagatcgt
    12541 tgttcgtgct ttagaagaac caattcgtca aatcgctgaa aacgctggtt atgaaggatc
    12601 agtgattgtt gataaattga agaacgtgga actaggcact ggtttcaatg ctgctactgg
    12661 agaatgggta aacatggttg aagcaggtat cgtagaccca actaaagtaa cacgttctgc
    12721 cttgcaaaat gccgcttccg tttctgcctt gttattaacg acagaagcag tcgttgcaga
    12781 taaaccagaa ccagcagcgc cagcagctcc tgcaatggat ccatcaatga tgggcggtat
    12841 gatgtaagaa aaagcaactt gcttatctac aactgatcat tagtgaaaga cagataaaaa
    12901 gaggctggaa cagaagcgtt taactccaag aaataagaag aaattcacgg aaattgcttt
    12961 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgctgtttat
    13021 acgtgtttag agcgtgagac aaaagtgttc tttacttttg tcccacgctc ttttttgtgt
    13081 gtaattataa tgaaaatagt tatttttaat agttataata ttttatctat taaaagtaaa
    13141 tatccattc
//
LOCUS       DAJSMK010000070        11928 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.073, whole genome shotgun sequence.
ACCESSION   DAJSMK010000070 DAJSMK010000000
VERSION     DAJSMK010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11928
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.073"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            560..1531
                     /locus_tag="ON488_001967"
     CDS             560..1531
                     /locus_tag="ON488_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HCR3232157.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(1609..1845)
                     /locus_tag="ON488_001968"
     CDS             complement(1609..1845)
                     /locus_tag="ON488_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCR3232158.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1814..1945)
                     /locus_tag="ON488_001969"
     CDS             complement(1814..1945)
                     /locus_tag="ON488_001969"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCR3232159.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(2021..2404)
                     /locus_tag="ON488_001970"
     CDS             complement(2021..2404)
                     /locus_tag="ON488_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HCR3232160.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(2437..3222)
                     /locus_tag="ON488_001971"
     CDS             complement(2437..3222)
                     /locus_tag="ON488_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HCR3232161.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            3400..4500
                     /locus_tag="ON488_001972"
     CDS             3400..4500
                     /locus_tag="ON488_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HCR3232162.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4490..5314
                     /locus_tag="ON488_001973"
     CDS             4490..5314
                     /locus_tag="ON488_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HCR3232163.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            5311..6126
                     /locus_tag="ON488_001974"
     CDS             5311..6126
                     /locus_tag="ON488_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCR3232164.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            6123..6953
                     /locus_tag="ON488_001975"
     CDS             6123..6953
                     /locus_tag="ON488_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232165.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            6960..7991
                     /locus_tag="ON488_001976"
     CDS             6960..7991
                     /locus_tag="ON488_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232166.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(8098..9371)
                     /locus_tag="ON488_001977"
                     /pseudo
     CDS             complement(8098..9371)
                     /locus_tag="ON488_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9648..9857
                     /locus_tag="ON488_001978"
     CDS             9648..9857
                     /locus_tag="ON488_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232167.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            9907..10623
                     /locus_tag="ON488_001979"
     CDS             9907..10623
                     /locus_tag="ON488_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HCR3232168.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(10525..11045)
                     /locus_tag="ON488_001980"
                     /pseudo
     CDS             complement(10525..11045)
                     /locus_tag="ON488_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11333..>11928
                     /locus_tag="ON488_001981"
     CDS             11333..>11928
                     /locus_tag="ON488_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3232169.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKK"
BASE COUNT         3434 a         2200 c         2721 g         3573 t
ORIGIN      
        1 ataacgtgat tttttgctgt aatgacaagg ttttagctgt ttcagatacc atgtatccaa
       61 aaatagttta ttgagaaaat aggagagtat ttgatactaa ctagtaggaa aaaatgagat
      121 aaaaagtaaa tggaatcatt taaggtaatc tgaaataaaa aatatacagc cctgtggtac
      181 tttacctaca aggctgtata tattttttac tctcagcgtt tttgactccg tgtctgactc
      241 cgttttattg attttgaatg ttattcaatg accatttaac aggtcaaatt tgatgttttt
      301 gattccgtat gacgccgttt gatatctagt gatatagtga tttgagtcta catcgaataa
      361 gggaataaac caataaaaaa tgatttagaa tattaaaata acaaaaaaga ggactacctg
      421 tattagtcct cttttttgac cagattttga ccagtctatt ttacatccta gtatatttat
      481 atgagctaat tttatgatta aatggtaagt ttttccttgt gtgttttagt ttaaactagt
      541 gtgtaattca aaaatctata tggaaggaac agtattaaga atagaacagg gttctctaca
      601 tgatggtgct ggtttacgga ccgttgttta tttaaagggc tgcccattac gctgtgcctg
      661 gtgttcgatt cccgaatcac aaagcaagca gattgaaaaa ggatttggcc agaccatgac
      721 cgctgaagag gtaatggatg agattgagaa ggatgctgtt ttttactttc actcggatgg
      781 cggagtgacc attagcggag gcgaggcact ggttcaggcg gattttgcta aagaaatttt
      841 gcaaaaatcg aaatacattg gaatcaatac cgtactggaa accagctttt gtggtgctta
      901 taatgaaatc caaaaggtag ctccctatgt ggatacattg tttgtggatg taaaaatgtt
      961 taccagcaag ctccacaaac aatggaccgg cttagataac caacaaattt tgaagaatat
     1021 tcgtcgcttt ttaattgagt atcctaactg cgaagtgcga attcgagttc ctgtggttcc
     1081 aggtatcaat atgaacctga ccgagctgct gacgattgct tgttttgtgg cagatcttga
     1141 tcggttcgta ccgttagaat tactaccgta ccactgctat ggtatgcacg gttaccaagc
     1201 attgggactg gagtatccgt tggcagacac gccagcgcct tcacctaaag aaatgtttgc
     1261 attggcagat caactggctc gcacggttcc tcatttgctg gtcacagctt taaccaaaac
     1321 atttatttat ttattgaatc caagctttat cttatggata aatgaaagac actcactagc
     1381 tgcagccagc tcaagaatag agcttttgct gaagtcagtg agtgtctttt tacgatgttt
     1441 tttcgaagtt aatttgtcga atgaacactg gctcaatcgg tacatcttca ctgtttgtcg
     1501 gctgagctgc gatcgctgct acgatttcta acccttggta tacctgtcca aaaacagtat
     1561 aacgaccatc cagctccggt agtcctccaa gctccaagta tgcttgcttt acattagcag
     1621 gtcagcctgc gcctttgtgt tttgcacaat aaaaaactgg ttgccgttgg tgtgggggcc
     1681 gtggtcccct aaggccaagg cgccattaaa atgataaagt ccgcgatgca cttcatcagc
     1741 gaaaaagccc tcatagctgg aaacagcttc atcaccagaa ccatccaaag cgccaccttg
     1801 aataacaaat tccttaatga cacgagccga aaggtgtgtt gtcataaacg ccttgctcag
     1861 ctagggagcg ccagttggct acagccaggg gagcttggtc aggaaataag cggagacgaa
     1921 tttcaccagc atcggtgacc agcacacaaa cttcttcctg ctgcggtttt tctaattgaa
     1981 agagaggaag gtttgcaact gaaacgcctt gatcctgcca tcaaatatcg aaaatccgcc
     2041 actcgacctt cgcctgatca ccaaggcgag ccattcccaa taaaacggta taggcggttt
     2101 catccgcttg aaaggtcaat tgcagctgtc ctcgtaaatc gttgtagtca tctggggcgg
     2161 ctacttgata aaaaagatga aactgcgcat gcaaatattc caaaggctga tctttaaagg
     2221 ctgcaaaata agcctgaact ttttcccgct gcaagctgtc agccaccaaa aaattttcca
     2281 gttgttgttt tggaacggct gctaacaagg atcggcaaac cgcctcaatt ttcaacgcat
     2341 cccaatgtcg cgcaattaaa taatggatgg gtgcctcttg attgtagtcc cacaggttgc
     2401 tcattttttt caccactttc ttctattata taggaatcac aaaatcggca gcggcgtcag
     2461 gcggcgttct tttccttgaa tgactagcaa cttttctacc tgacagtctg ccaacagctg
     2521 actcattttt ttaaagccca gctgataatc ttcggcaaca tgagcatccg agcctaaggt
     2581 aaagagcttt ccgccgacac tttgatacaa aggaacggca taacggtaaa ggtcttcgtt
     2641 gccgtatttc aagaagctct tggcatttaa ctccatcgcc aattctcgtt caacaacctt
     2701 tttgaaaatc gttagcagct gagcctcaaa atgctccgcg aattcttccg ctgtgaaggt
     2761 gaagcggcgt aatccataat caaagtgagt caaaatatct ccttctggaa aatccgtcaa
     2821 gacctgcaac atctgatcaa aatattcctt ggtagtttga atgggatctt tggttaaaac
     2881 cacatcgtcc atataatcaa agcggccatt ttgatgaata cttaccagct ttaaatcata
     2941 aggatgctga gcgaggtaat ccacgatccg ctcttcttgt cctggaacaa cgccaatctc
     3001 gatacctcgc agaaatttgg tggaataggt ttcttttaaa gagtccagtt tgtttatata
     3061 ggctggataa tccggaatgt catcttttcc ggtagatgga ttgtttaaat caaagtgatc
     3121 cgtagaaacg aaaaactccg gctgataggc taaatagttt tcaaattttt cctctgaatc
     3181 aaaggaaaaa tacgtgtgga gatgctgatc ataatactgc atagggagcc tccttttttc
     3241 tactatcata ccgcaaaagc tttagaaggt taacgggaat tcgtcgaaat ttacaaacca
     3301 tatacaacct ttacattgtt catgaaacct tttcaagaaa ctgattctct cattacaaag
     3361 ctttgttaga atggaattat cgaaagggga gaagaatgaa tgaaaatgaa tgaaaaaatt
     3421 cgtaacatga ctatcggttt attttgtgca gcaacagtaa gtatcctgct gacaggctgc
     3481 ggctcaggtg aagcaacgaa gcaatcggct gcggcagacg actctttaga tacgattata
     3541 gaaaaagcca aggaagaagg agagattgcc agcttgggaa tgccggatac ttgggcaaat
     3601 tgggtaggca cttggaacga ccttgaaaaa gaatacggct taagtcacgt ggatacggat
     3661 atgtccagtg cagaagaatt ggctaagttt gaatcagaag gaaaaaatgg aaccgccgat
     3721 attggtgatg tcggtatcag cttcggtccg ttggctgaaa gcaaagagtt aaccttacct
     3781 tataagacca actattggga ggaaattccg gattgggcaa aggatgatga tggggattgg
     3841 ttgttaagct atacgggaac catttccttt atcaccgata aagagaatgt gaagcaagca
     3901 ccgactagct ggaaggagct gcaagagggt gactatcaag ttagcgtggg ggatgtgacg
     3961 attgccaacc aagcacaatt tgctgtattg gctgcggcga ttgccaacgg aggtgacgaa
     4021 aaggatattc agccaggtct gaattactac aaaaaaatgg cagaaaaagg ccgtttgtcc
     4081 accgttgatg ccagcgtagc aaatcttgaa aaaggtgaaa tcgatgtggc agttgtttgg
     4141 gacttcaatg gactaaatta tcgtgaccaa attgactccg agcgttttga ggtaactgtg
     4201 ccaacagacg gctccatcat tagcgggtat acaaccttaa tcaataaaaa tgcccctcat
     4261 cccaatgcgg caaagctagc acgggaatat attttatctg atgaagggca aatcaatttg
     4321 gcaaagggct atgcgcgacc tattcgcaag gtagagctgc ctaaagaagt agctgaaaaa
     4381 ttactgccgg aggatgctta tgaagcggcg gtgccagttg aagacaatga agcttggaac
     4441 aagacctctg tagagcttcc agagctttgg caggcggagg tactgaccta tgcaaagtag
     4501 acttgacaaa ctgattgtag ttatactaga cggctgtcgc tacgacacag ccgtcgccca
     4561 gcttgggttc atgaatcatt tagttgagca ccagcaagca agcttattga aggtaaaaag
     4621 tgagctgccc agcaattcac gtccgttata cgaagtactg atgaccggcg ttccagccta
     4681 tgaaaatggc atctatagta attaccatgc tcagcgatcc aaagagtggt cgctgtttga
     4741 attagttaag gaagctggcg gaaaaacagg agccgccgct taccactggt acagcgagtt
     4801 gtacaatcaa gccccctata atcgtttggt tgatcgcatc cagcatcagg aggagcgact
     4861 gattcagcat ggcatctttt atagtgagga cacttaccct gattcgcatt tatttgcgga
     4921 tgcccattat ttagtgaatc agtatcagcc agactttttg gtcgtacatt cgatgaatat
     4981 tgatgatgtc ggtcacaaat ttaccgccga ttctcatgaa tatgcagcag cggttaatca
     5041 ggcggacaga ttattggcta tttaccttcc tgaatggctg caaaaaggtt atcaagtcgt
     5101 ggtgactgcg gatcacggga tggatgcgca cggactgcat ggcggcagct tggctgcaca
     5161 tcgtgaagtt cctttttatt tgatttcaaa taaacgccaa aagctgaagg aacaaactgt
     5221 accacagctg ctggcggctc cattgttttg ctggttatta ggaattgcac cgtcagagaa
     5281 aatgcaggac attcaagaat tgatgagggg atgaaagaga tgaaaaaacg cttggttctg
     5341 gttcctgcct cctttatctt ctgtgcattt ttactgctgc cgctgctttt tatggttctg
     5401 tgcagcttgc acagtgattt aactaaccag tggacattgg ccaattacag tgatattttc
     5461 agcaacaaat attacacaca ggcctttgtt aacagcgtac tgattgctgt cagctccagt
     5521 gtgattgggt taatcgggac gtttatttta tgtttatgct taatgaatct atcgactaaa
     5581 ttgcaggaga aaatcacctt tgtttccaat ttggcagcta attttgctgg gattccgctg
     5641 gcattctctt ttattatttt gttggggaat gtaggtgtgc tgaaaatgat tttgccattt
     5701 ctagcggact tcaatttgta ttcttggtgg ggattgacca tcacgtatac ctatttccaa
     5761 attccgttag gggtcttgtt tttgtatccc agcatgaagg aagtgaaaaa ggaatggctg
     5821 gagtccgcac aattgctggg cgcttcatca gcgtatgctt ggttcaaggt ggctttgcct
     5881 tttttgcgac catcgattgc cagcaccttt gtcatcttat ttgctaatgg catggggacc
     5941 tatgaaacag cgtatgccct gaccagcagt aatgtaaatc ttttaacgat tcgaattgcg
     6001 gctttagtgt cgggagatgt gttcgccaag cctaatttag gcagtgcgtt ggcagtcgct
     6061 ttaggtgtcc tgctggtaac ggcaatgttg attattcaaa agaaaggcaa ggtggtgcag
     6121 acgtgaaaaa gttaataaaa ccgattttgt tctgctttgt cctgtattac ttgctgccga
     6181 ttattggaac gattttgtat gccagctcca ctaaatggtc aaaatcgctt ttacctagtg
     6241 attttacctt gcaatggttc caacagctgc tgacggacag ggaatttatt gctgcggtgg
     6301 gtcgctcact tttattagca ggtgtggtct tggtgacgat tctgttgttg atgattccca
     6361 ccattatttg gattcatttg tatttccctc gtttgaatcg ttggctggaa aagctgctcc
     6421 tgctgccgta tgctttacca ggagtgattt tggtaacggc tttgcttcga acgtatgctg
     6481 aaactggtat cccaatgttt gtagtgttgg taggtgcatt gtttattacg gcgttgccga
     6541 ttgtctatct tagtcttaac aaccagatgc gcttaattaa tctgaaggaa ttagtggatg
     6601 cagcagaaac cttgggcgcc ccgatgtcta cgattattat ccaggtgctg tttccaaaca
     6661 tccgtatcgg tgtgacccta gtttctctga tgattttttc ttcggttttt ggggagtaca
     6721 tgctgacgaa cctgttgatt ggcggtcgat ttcagacggt acgcatctat atgctgcggc
     6781 ggatgaacga aaacggccat ttggctagcg ctgtgatggt tttgtatttg ctgtttatgg
     6841 tgggaattgc tttaactacc tttatgctga cttatcgaca aaagcaacag ctgtccctta
     6901 agcagacgag ggaagagaag cagtcgaaaa agaagccctt aaaggagttg tgacggaaaa
     6961 tgtttttaga aatacatgat ctcaatctgt tttttgatga aaaacagatt ttagctattg
     7021 atgaaattca gattgaaaag ggtgagctgg ttactttact aggtcccagc gggtgcggaa
     7081 agtctacgtt gctgcgctgt atcacgggat tggaacaacc aaagagcggt gagattgtgc
     7141 tggacaatga gaatattgcc gataagccta cgaaggatcg caatatcggc tttgtttttc
     7201 aacagtatgc attgtttcca actatgactg tttttgaaaa tgtagccttt ggtttgaagg
     7261 taaagaagct gagtcctgag gtgattcagg aaaaggtttt tgagatgcta tcattggtgg
     7321 atatgacgga gcaggcagat aaaaatgtcc agtttctttc tggcggtcaa cgacaacggg
     7381 tggcactggc tcgctcattg gtcactgaac cgaaagtcct gctgctggat gagccattaa
     7441 gtgctttgga tgcccgaatt agaaaacagc tgcagcggga tttgcgcgct atccagcaat
     7501 cgctagggat gacgatgatt tttgtgactc atgaccaaga agaggcgatg cgaatcagtg
     7561 atcggatttt tgtgatggaa gctgggcggg tggctcaggt ttccacctcg aaggaattgt
     7621 atcagaatcc tcagagccga tttgttgcgg aatttatcgg caactataat cgtttcgaat
     7681 ggtatgagct gaatcagtat acccacgagt tttccgctaa gggcaatcgc tgcatttatt
     7741 atttaagacc ggagctgatt caatttgaac cggttcctca gggggttaag attccggttc
     7801 tatggaagga atcatttatt ttaggcaaca ttcaacggta tgtttttcaa acgctggagg
     7861 gcaaagaaat tttagtggat cggttgaacg atcgggaaga gaaaattagc gatgccttat
     7921 acattcagct gaaagatatt ctagcaatcc ctgtggaaat tgatactcag cattttgcac
     7981 aacaaagcta gtgtatagtc ggcaaacatt tctggctctt tgtcaaatag gactgataga
     8041 gtgatataag aacatctaag gtagaattga ttttctgctt tagatgtttt tttatgttta
     8101 ataagtgatc agatgattga ttaagaaaat tctggttctc atcctaaccc gtaagctatt
     8161 cgtttcaatg ctttgatgtg ggtatgcaga ttttctattt tgccatttga gtaaggcaac
     8221 tctaaggcta aacgaatgcc ggattcatag tttataaacg ctttttttat atgatgcagt
     8281 tctcttggaa ccgacttggg cattgttttt acaagctgaa agaagatgtc cgcttctttg
     8341 tcataaaaag cttgaagaat ttcttgatag taagcataag ctattcgtag ttcatcagaa
     8401 gtagaaagta gacgttctac gacttcactt tcggttaaat aggcccaacc aaaattacgc
     8461 cattttgtcc atttatcata aacaagcgtg tcctgtcgtt tgatcagaag tcgagataaa
     8521 gccttcactt gtcgatagtg tttggcttgt attggatcgt ttcggtcgaa gcttttcatg
     8581 actcatagtc aaatatcctt aaaactgcga atgaggtgct tgacgatgtg aaagcgatcc
     8641 acaacgagtt tggcatgagg aaagcactct tttatcagca aagcataaga ggcgttcata
     8701 tctgttacga gtatttttac gtttaaacgt gcacgtcgtt caaattgcat aaaataagaa
     8761 atgagatctt tcttcttacg tgaaggaaga atatccagta atttcccagt atcgccatcc
     8821 atacaagaaa aagaataggg accgacttga tttttcaatg aacgaaattc atctaccaat
     8881 gaacagcgag gcaaccaatt tattttcacg tttgtcatgg ggagcagaga agcgagtgtt
     8941 cgcgaaacgg ttgaccaaga aacgccgcaa tgtttagaaa tcgtcgtcat tgcttgtttt
     9001 tcagtcaatt cctccaatat tttataatgt acttgtttgg cgataaaaca gtttttttca
     9061 acaatgtagg tattcgccgt aaaataggtg tgacagccac gacagaggta ccgttgcttt
     9121 gccaaagcaa gataagtccg ttgattcgca cacttattga gaaggaccag cgattttttc
     9181 tttccgttct taacgatcag cccatgttga ttcacctgtt tacactgagg acagggctga
     9241 atcgttttaa tgagcgtggc agaaacaacg atactgttga ttgaatgtat ttttttcttc
     9301 tcgacatgag tgatttgaat gtttccatct ttgattccta gtaatagttt gataagatga
     9361 agatcaggca tacagaacgc tcctttgatt gtgttgtggt gattcaattc taacggagct
     9421 tctgtatgtt ttgttttttt atgctcaaaa ggactgatag aatgatttac tatcagtcct
     9481 agaaattata gcgccacatt tctttcacct ttgacttttc agacggcagt ttttatgctg
     9541 atactgtaga gagagcagga cacagctttt gcttgttttg ggtaaggggg aaagaagatg
     9601 accaaagcac ttatttttga ttttgatggg acgatgattg acagtgaatg gatgttttac
     9661 gagagtattc atcactattt actgaagcct atttactgga gcagttcggc tataaaattc
     9721 cttttgcaga ctatcaacaa ggtgttggga cggcagcaga actgtccttt tatgaaggga
     9781 taagtcaagc ggttgggaga ccagtggatg ctgaacattt tgagcagcgg atcagcagca
     9841 ctggaaaatc ggagtagtct caattctgaa ctgcgggagc tagactattt ttttgaagca
     9901 catccgatga ttaaggaaaa aattgattcc tttgtgacga tcgatgatct tcaggtcggc
     9961 aaaccagatc cagaaggtta tttgttgtgc ttgaaacggc tgagggttga acaggctgtt
    10021 gtagttgagg atagtccagt cggtgcccaa gcagcaccgc atatgacagt tgatgtacaa
    10081 gcgttggatg cagatttttt cgcctttagc gggcataaaa tgtgcgggcc gacaggaatc
    10141 ggtgtattat atggcaaacg tcaattgtta gaacaaatgg agccagtcga attcggcggt
    10201 gaaatgatag attttgtcaa tctttacgat agttcatgga aagagctgcc atggaaattt
    10261 gaagctggta ctccgaacat tgcaggagca atcgattact tgaatgagat tggtatggag
    10321 aatattcatc gttatgagca agaactggtt gcctacgttt tacctaaatt acaagcgatc
    10381 ggcggtatca ccatttacgg accgcaagat cctgaacatc atactggcgt ggttgctttt
    10441 aatttggatg gcatccatcc ccgtgatgtg gcgactgctc tggatatgga aggtgtcgct
    10501 gtacgttcag gacaccattg tgcacaacgg ttcatcgacg atttctgttt gactaattgg
    10561 tcgtttaaac agtcgatgat aatgccgttt gagcggctcc aatgtcgtgg aatctttgag
    10621 taagagtttc caatatcgct tgagccgacg gtacttcttc tgattttcag attacgtgat
    10681 tgattttcgt acagttctat gagaatcgcc tgcttcagtt cctttgttag ttgatgatgt
    10741 tcatcaacta agtccgtttt cgcagaaaag gtctgcccac aatcatagca tagaaaacgg
    10801 gtacgtttta attctaaaat agtcaacttt tctttgactt tcaacatctg agtacgtgtc
    10861 gtataggaac cgttgcggat aatacgaatc gatccacagt gttcacaatg ggaaggtgag
    10921 tcatccaatc tccctttaat aaactgcgct tgaacgcctt tatattcttt ttcaatcagc
    10981 cattcttcat caaaaaataa atgtttatct gttaatccga gtaattttct agtatgatta
    11041 tccatagagc gactcctttg gtagggtgat gttttggtcg actaaatttt accaaaagtg
    11101 agtctctttt tgagttgaaa cgaagaaaaa gtgttagtag aaaatcgcct tcgattttcc
    11161 aacaacacaa aatattatag aagccttttt tctaaaggat ttcaaggtgt ctgtttgcat
    11221 ttattaaaaa aaagaaaaag tattggcaac agaaggcgtc accaacacta gatattatag
    11281 agccataata tgctgtataa tatctagtgt ataggcttaa gtggaggtat atatgaaaat
    11341 attaactgtt gaagatgata atatgataag agagggaata agtgaatatc tttcagaatt
    11401 tggatatact gttattcaag ctaaagatgg aagagaagcc ttgtcaaaat ttaatagcga
    11461 tataaatttg gttatcttag acattcagat accttttata aatggtttag aagtgttgaa
    11521 agaaattaga aagaaaagca atttaccaat tctaatcttg actgcattta gtgatgaaga
    11581 atataaaatt gatgcattta ctaatttagt agacggatat gtagaaaagc cattttcatt
    11641 gccggtctta aaagctagaa tagattcttt aattaagaag aattatggac atttagagaa
    11701 gtttgaatat aaggatctat cggttaattt taatagctat acagctaaaa taaatggtga
    11761 agaaatagat gtaaatgcaa aagaactaga agtattaaaa tgtttattgg ataataatgg
    11821 acaagtgtta acaagaatgc aaattattga ttatgtatgg aaagatagcg aagaaactcc
    11881 ttatgatcga gtaatagatg tatatataaa agaacttaga aaaaaatt
//
LOCUS       DAJSMK010000071        11782 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.074, whole genome shotgun sequence.
ACCESSION   DAJSMK010000071 DAJSMK010000000
VERSION     DAJSMK010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11782
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.074"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(157..681)
                     /locus_tag="ON488_001982"
     CDS             complement(157..681)
                     /locus_tag="ON488_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232170.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(674..1147)
                     /gene="tsaE"
                     /locus_tag="ON488_001983"
     CDS             complement(674..1147)
                     /gene="tsaE"
                     /locus_tag="ON488_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HCR3232171.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1270..2250)
                     /gene="pta"
                     /locus_tag="ON488_001984"
     CDS             complement(1270..2250)
                     /gene="pta"
                     /locus_tag="ON488_001984"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HCR3232172.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2403..3083)
                     /locus_tag="ON488_001985"
     CDS             complement(2403..3083)
                     /locus_tag="ON488_001985"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCR3232173.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3209..4078
                     /locus_tag="ON488_001986"
     CDS             3209..4078
                     /locus_tag="ON488_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3232174.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4104..4619
                     /locus_tag="ON488_001987"
     CDS             4104..4619
                     /locus_tag="ON488_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232175.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4666..5259)
                     /locus_tag="ON488_001988"
     CDS             complement(4666..5259)
                     /locus_tag="ON488_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232176.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5284..5463)
                     /locus_tag="ON488_001989"
     CDS             complement(5284..5463)
                     /locus_tag="ON488_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232177.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5540..6049)
                     /locus_tag="ON488_001990"
     CDS             complement(5540..6049)
                     /locus_tag="ON488_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232178.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6145..6525)
                     /locus_tag="ON488_001991"
     CDS             complement(6145..6525)
                     /locus_tag="ON488_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3232179.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6855..7604
                     /locus_tag="ON488_001992"
     CDS             6855..7604
                     /locus_tag="ON488_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HCR3232180.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7788..9065)
                     /locus_tag="ON488_001993"
     CDS             complement(7788..9065)
                     /locus_tag="ON488_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232181.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9144..9788)
                     /gene="pcp"
                     /locus_tag="ON488_001994"
     CDS             complement(9144..9788)
                     /gene="pcp"
                     /locus_tag="ON488_001994"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HCR3232182.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9987..10931)
                     /locus_tag="ON488_001995"
     CDS             complement(9987..10931)
                     /locus_tag="ON488_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HCR3232183.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10933..11619)
                     /locus_tag="ON488_001996"
     CDS             complement(10933..11619)
                     /locus_tag="ON488_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HCR3232184.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         3363 a         2484 c         2065 g         3870 t
ORIGIN      
        1 tattttgccg ttttttgagc taataccgaa ggtcagctga ttgaacaccg tttattcaaa
       61 aaaaatggac tgcgacacga cttttgtcac agtcccttcg tgtgtttttc tgccttctca
      121 aaaggatgac agtttctcac tcttttccta tttcttctat tcaatcaaat aactcatttt
      181 atatacatct aaaaattcac ctagatctgt tcttgcccct ctaggcatga ccgcttcgat
      241 ttggaagccc atttttcggt aaaggtgtac ggctctttca ttacgaactt gaacgtcaag
      301 ctccaatcga aaaagtacac ccatttcctt cgcccaactg atgatttctt ctagcataag
      361 agtgcctagt cccattcccc aatattcctg cagaatactg ataccgactt ctcccacgtg
      421 agacaaacga aattgactgt ctgccttgac agatgctgtt ccaataatcg tcccttcata
      481 gattgcaagc agcaataaat tattattgct ttcgtatata taatccaact cttcttctaa
      541 ggtttctggt ggtaacagga gttctgcttc atccaaaact aaaaattctg tctccttatt
      601 aacttgtccc atcatcaaaa gaatgtcttt tgcatctcct ggcactgctt cccgcaagat
      661 gatcccaact tcttcactca tgattttcag cccatttttc tagaattcgc tgtttgaagg
      721 tttcactttg ctccccgtat gagattagtt tcacataccg cttttctaaa tctgtatcac
      781 ttttttctaa aatcagttcc aaataatcct ccggcagtgc ttcttctaat agatttcccc
      841 attcaacaac ggaaagccca tcaccttcaa aatattcatc taaccctaaa tctgctccgc
      901 tagctgctac ccgataaata tccatatgat acaacggaat ccgaccttga ctatattctc
      961 taataatcgt gtatgtcgga cttttgatca tttgcgttat ccctaatcct tgggcaattc
     1021 ctttcgtcaa cgttgtttta cccgcaccta gatcaccagt caatatcaga ttgtcacctg
     1081 gcattgcgga atgaccaatt gcctctgcga attgttctgt cattgttaat cctgatagtt
     1141 cgatcatttt tcatcttctc ccgctcttct ttctttttgc cagtatatcg cgtaatgaag
     1201 tttttttaaa gaaaaaatga actagtcaag aacagcagct gctgtttttg gctagttcgc
     1261 gtgtatttgt taatcaatca atgtttgtgc tgctgtgata atcgataatt tatatacatc
     1321 ttcttcattt gctccacgag acaaatcaga aaccggtttg ttcaagcctt gtagaattgg
     1381 tccgattgct tcaaagttac cgaaacgctg agcaatttta tagccgatat ttcctgactg
     1441 caattctgga aatacaaaga ctgttgcttg accagctact tctgaatctg gcgctttcag
     1501 ttgtgcaact gaaggaacat aagaagcatc aaattgcaat tcgccgtcga tcatgtattg
     1561 tggcgctagt tttttagcga ttttagttgc ttcaactact ttgtctactt ctggcgattt
     1621 cgctgagcct tttgtcgaga agctcatcat tgctactttt ggttcgatat cgaacaattc
     1681 tgctgttttt gcagaatcta cggcgatttc agccaattct tgcgcagttg gattcacgtt
     1741 gatcgcacaa tccgaaaaga catatttttc ttgatctctt ccacgtacca tgatcatcgc
     1801 tccgcttgtc cgactgatgc caggctttgt tttgatgatc tgaagtgctg ggcgaacagt
     1861 gtcgccagtc gaatggatcg ctccagagac cattccgtct gcaatcccca tatacgtaag
     1921 catcgtacca aagtaattca catcttttaa aatcttttct gcttgttctt tggatgcctt
     1981 tccatttcta cgttcaacaa aagtatccac catttcatcc cacttatcgt aattatcagg
     2041 gctgatgatc gtaaagctag atgttttgat tcctctggca tgcgctgcat ttcttatttc
     2101 ttcttcgttc cctactaaaa tgggttccac aagttcttct gctttcaacc gggcagctgc
     2161 gcctaaaata cgagcatcag tagcttccgg gaaaacgatt ttgatcccac ggcgaacaat
     2221 tttaaatctt aaactatcaa acaattccac aagatgacct ccagacgttt ttatatgtat
     2281 tatcatacac tattccagaa aaaaagaaca gtttatttta tctgtatcag tcaaaaatgc
     2341 tggaaaaatt aagtttttca catacaaagc gaactgcact ataacaggaa agcgctgttt
     2401 tattacactg tttcaggcag ttgccaatca atcggttctt ctcctaacgc aaggagcgca
     2461 tcattcgttt tcgagaaggg tttggaacca aaaaagccac gacttgcaga taacggactg
     2521 ggatgtggag atgttatgat gatatggcga ctcttatcga tcattttgat tttttcttgt
     2581 gccggttttc cccacaagat aaacacgatt ggtttttccc gttcatttaa tttttcaatg
     2641 atcgtgtctg ttaatctttc ccaacctttc ccgcgatgag aatacgcttg cccttcccga
     2701 acggtaagaa cggtgttgag taaaaggact ccctgtttag cccatgacac tagatttcca
     2761 tgttgaacag gtgcgattcc aagatcatca taaagctctt tatagatatt tcttaacgat
     2821 ggcgggatct ttacgccagg ttgcacagaa aaagataagc catgagcttg attttctcca
     2881 tgataaggat cttgtcctaa aatcaccact ttaacttctt cataaggagt caattccaat
     2941 gcttcataga tatgatacat atctggatgg atcttttggg acgcatattc tttttttaaa
     3001 aattctctta gatgcagata ataatctttt gaaaattctg aggacaaaac ttcttgccaa
     3061 ctgttatgaa tgatttcttt caaaaactcc acctcctaat aaaaagaata actcacattt
     3121 tcttcaatca caagggacaa tcttcaccct cagcacttga ttaatatggt aaactaggaa
     3181 caagaagcag aaaggaacga taatcattat gatcaaatta attgcatcag atatggacgg
     3241 cacattatta gatgcccata tgagtgtttc tcctgaaaat gccgaggcga tacgttttgc
     3301 aaatgatgcc ggtgttgagt tcatggtcgc tactggtcga aactatcaag aagctcgcgc
     3361 agctttagat gaggtaggaa tcgattgtgc gatgatcact ttgaacgggg cacaggtatt
     3421 tgataaagaa ggaaattcat tgtttaccgt gtcgattcca aataatcaag caatctctgt
     3481 tttagatatt ctagatgcta acggtattta ctatgaagta gcaaccaacg atggtcttta
     3541 ttctgaaaat caagcgaaac gaattgaaag ttttgcttcc atggtggcta cccatttacc
     3601 tcaccttacg tataaaatgg cgattgccat ggcctcagct aagctggagt tattgcacat
     3661 cacatacgtg gacagtattc gtgctatttt ggaagaaaag aatctggaag ttttaaaaat
     3721 tatttgtttt catacagaag ggccagctgt attaggtcca gttggaaagc agatttctct
     3781 tttaggcgat ctagccgtta cttcctctgg tcaaaacaat atcgaagtga accataaaaa
     3841 cgctcaaaaa ggaattgctg ttgcccatgt cgctcacgag cgtgggattt ctttagaaga
     3901 agtcatgacg attggcgata acttcaatga tgtcagcatg ctgcaagtag caggagtcag
     3961 tttcgcaatg ggaaatgcag aaatcgaagt aaaagattat gccaaatata caacggacac
     4021 aaaccttgaa tctggcgtag gaaaagccat attgcgcgcg attgcagaag acttgtagtt
     4081 ttatctagaa aagagggata tagatgtcag aatttttcat tcaggaaaag cagcttggac
     4141 gtgcaactcg gacaattgtc aaaaacgaaa aaggacattc cctgtttttg atggttggtc
     4201 gctggggaac aaagggcgat gcattgtctc tttatgccat gaatggcgat ctcgttgctc
     4261 acatcaagca gataagcctg acattcggta cgcgttttga gctgtataaa gagttcgaaa
     4321 aggtgggaac catgcagaaa atattcaatt ggcccggtga cttttattat attcgtagac
     4381 ttcactggac agtccaaggt gatatctata atcatcaata tcaaatccat catttcaatc
     4441 agcaaatcat gaaaatggat aaagcaacac ttttttcagg agattactat gtattggatg
     4501 tctcaaatga tgaagatgct ccagtttgta tttgtattgc tgcggtttta gattactggc
     4561 tctaccgtaa agacaaaagt cgcgataagc ctgtttctta ccgacttaac ttaagttaaa
     4621 aagatgtacc tgaaatgcgg aaatacgcat ttcaggtaca tctttttaga tattcttttg
     4681 catatgatca taaagatgac cactgatcat ccgctgaccg acaactttga agtcatggcg
     4741 ttcgtataat tttttagcct ttggattttt ttcatccaca cttagaccga tgacggagcg
     4801 attagctttc ttcgccaatt taggtaatgc ttctaataat cgcgaaccga tgccttgtcc
     4861 tctaaaatct tctgatacac tgatagagtc caaataccat tcgttgggaa acgtttcttt
     4921 atcaatgaac aaacgtgtag acgcatctag ctgatatttc tctaagatag gtaccagtgg
     4981 ctgatcgatg attgattctt cttcatctgt ataaccgtaa gcaactcctg caactttacc
     5041 gtctatttct tctacgatac ctcgtgaata actgtaacga taatttggat cagtgattgc
     5101 ttcttctaaa atctctaaag tcttttgttc ccctgtctgc ttcaaaaatg gcagttccat
     5161 atcttttaga atcactaaga tcaatggggc gatttctgga gcatcttctt ttctcgcaaa
     5221 acgaatcata gtttcctctc cttttctcca ttctaacatg cagaaaaaga aatcgcaaaa
     5281 tcgttatttt aaaaaatctt caatcttttc agtaatgaaa taaccatgag taacgattct
     5341 tgccgcttca gttcggcaat aagggcagac gactggcatt tctttatcat tatgttcgac
     5401 tacattattg acttcttcgt atgcaaattt ttttccgcaa ttagggcatt tcattttttc
     5461 catgttatct caacttcctt tcatctttac tctcttagct tactcttata ttgtaaaaaa
     5521 gagaagcaat atccttcttc tatgcagata tccatacctg acggtcctgt tctccatcta
     5581 ttaatcggac tttataataa ggacgttcat ctttgactag aagtgtccac tctttcactt
     5641 ttgctttttt cccgtagtag ctgactgctt ccttcatcgc tgcttgcggt tgtttgaact
     5701 cttccgtttt ttctatatca aaaagatgtt ctgcggcctt ttccgtgtca tttcgtacgg
     5761 ttgttttccc agtggatgga ttgactgcta tgacttgtcc ttcacaaaaa aactggtatt
     5821 catatgttgc attcgtagga ttctccaaat ctttttcaac tgcaaaatga atagcagata
     5881 tgttatgttc ttttgtttcg ttttttacga ttgctgctgc ttttttcaat gagatccgat
     5941 attcctggtc actaatatca tccatgtgaa aagcggcatt gagcagtccc gtcataccgg
     6001 taatccctat tacgatgagg gcagcaacac caaacatcat ttttttcatt cttcattctc
     6061 ctgtttcttt tttttaaaga atatcaagaa atgaacgaat gaaaaatcga atgaaacgaa
     6121 aaaaaagtga caattttgtt atctttattc gtgcagttct aatggcaatc cgtctggatc
     6181 aaagaaaaac gtcatttttt ttcctgtaaa ggtatcttct ctaatcggtt ctgattcgat
     6241 ccctaaggac tgcaattctg caattgtttc ttcaatatcg tctactttga aagcaagatg
     6301 acgcaagcca caagcttctg gatagtttgg tcgttgtggc gcattagcaa ttccaaaaat
     6361 ctccaattca gcacttccta gtttcagatc taatttatag tcatctcgtt ctttgcggta
     6421 attttctctg attacttcaa atcctaattt attaacataa aaatcacgtg atttctgata
     6481 atctgaaaca atgatggcta tatgatggat cgttgtaagg ttcatatgag cactcctatt
     6541 cttcgtttaa gctcggatct atattaatct ccagttccat tgtaaatgtg tcagattgaa
     6601 aaaaatagct gtttttcctt tttataagaa aaaaggcaaa aaaaacagaa agtaggtcct
     6661 ccaagacact cttcctgttc ccaatataat aaatgaaagt aagaaattat attttcaaga
     6721 aaacaaacag aaaattatca taacacaaat tatttataat tgaaagacta gttttttttc
     6781 aagaaaagca tacaatagat tgtgttagta aatacagaac acactacatt tagtgtctta
     6841 aggagtcctc atacatgaag tcatattttc agtttttagc tcatcagcta aaaggctggc
     6901 cgcaacaaaa ttattatctt ttctttttca gtcttggctg ccaggtcatg actcttgtca
     6961 atagtcccat cacttggctg tccgttatta catttatcgg taccacgctt ggtgtattgt
     7021 gtattttatc catcaatgcg gcaaaatcag tcaacggtat tttaggtatt ttgtctgcga
     7081 tttgttttat tatcgttggg ttttcagcaa agaactattt aagtatcggt gaacagattg
     7141 cttatatgat cacattggat atccccgtat tgttaagtaa agaatggaat cataatatgg
     7201 cttcaaaaat ccgaaaattc actggaaaaa gctggtttat cgcaatcatc agtactttcc
     7261 ttgtctatct tgtttcagga ttcctgattg gtcgttatac agatgatcct cggccgtggg
     7321 tagatgccat tgctttttct attagcttga ctgctggtat catcagtttc ttgcgttaca
     7381 acaaccaata ttactggtgg ttagcttcag ggcttgctca aatggtcctt tggtatattt
     7441 catttacgca tggatctgca agtttggcga tgttcgtgaa tagctctgtt tacttgctga
     7501 atgatgtcct tgcatttacc gtttcacctt ggtataacca aaaagaacgt gaacgtatgc
     7561 aaaaaatgga agaagaatac tacaacgcac aacaacacgc ataaaaaaac tgagcgtggg
     7621 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaatcagaa
     7681 gcaactcctt cggaaataag ctgaaattca caaaaatttg aaaagcaatt ttcgtgaatt
     7741 tcttcttatt tcttggagtt aaacgcttct gtcccagcct ctatttttta tagtaattcc
     7801 ttcagatact ttcttgcctc atcattgaaa cgcagtgatt cttctaactt ctgataatat
     7861 tccaacgctt gtttctgagc ttcagtaaaa cgataatgtt ttcctttcca tttgtcgatt
     7921 gtctcttgca catttccaga ttggatatct ttcactacta gttgccattt ttcttttgag
     7981 actgtacggt ctttcttatc agcagattgt atagcttctc gttctttacg caatactttt
     8041 aaaaaaccat ttctgactat ccgaggaatg ctgtcgaaga acccttctgt aaaaccatag
     8101 cgacaatatt gcttccaaat aaatagatag atttttggtt ggatgaatcg ttggtttttc
     8161 gcaaaatatt ccatctgagc agtgacttct ggtgttcgtt gacgttttgt ctttctcaac
     8221 acggaaataa atgtttcaaa ataagcatta ggatgtactg gcacttcttc atatacgatg
     8281 gattgccaat ctttacgtaa aaatgcgcga tagttgatca agaattcttc tacatccttt
     8341 actaattctt ctgcaaagtc gtcaaatagt tcttttttta tctgtcgctt ttttgactgc
     8401 ccattgatgt gttcacttat tttcttgatt tcattttcca atgcttgata atccgctatg
     8461 taaatcggca tttctacttg gcgaaattct gcgagccgct gagctaattt tatatccggt
     8521 aaatatggct gtttcatccg acgattttgg tacaagacaa aacagtattt ttgccatagt
     8581 ccttcaggaa aatcgatatt cttctgctta agccataata attcgtctaa ggccagatca
     8641 acttttgtca ttccctgatg gatcgaagct gccactgtcg gagagacatg caggtgatcg
     8701 gcaaagtggt tgatgcctag ttttaggatc tttccggttt ttggcgattt aacgatgtat
     8761 tgcactttta attctctacc acactcacaa tacaattttt gctggcttcg ttttgttcga
     8821 aaaaacggat tgatcttgaa gtcagaaaac acccaatctg ttgcagctaa ataatgttct
     8881 tccataaaac gagagctgat tagatatcgg cggtgcttat cgactagttc ccgctgtttt
     8941 ttcgttaatt ttgcatagat ctcccaacgt tgactgcttg tgtattgttt agaaattttg
     9001 atgggatagc ttttgctgat ttcttttgga aaccattctt caaagacgga ttgccattct
     9061 tccacggctg tttctttcct ttctaattac aaaaagctgg ctactaacat aacgttagca
     9121 accagccagt gtttcttgct aaattagtga gttgttccgg catttccgga aatatcttct
     9181 ttattttcta ctgctgcttc aactgcataa gtcaaagaag aagcaatgtc ttctaaagac
     9241 atagaaggcg tacccactgg acgatcgatc acttgatcgg gtgagaatgg cacgtggatg
     9301 aacccacctc gaattgccgg gaattgtgtt tcgatcaaat gaagcaaacg atacatgata
     9361 tcattgcaga caaatgttcc tgctgtataa gagatgtacg ctggtagacc atgatcttgt
     9421 acattttttg tcattgcttt gattggcaat gaggtaaagt aagcggctgg accgttttct
     9481 tctaaagccg tatcgaatgg ctgatttcct tcattatcag ggattcttgc ttctgctaga
     9541 ttgattgcga cacgttcgaa cgagactgct gaccgcccac ctgcttgtcc gacacagatc
     9601 acgacatctg gttggtgctg ttggatggct tctttgacta cttgactgct tttttcgaat
     9661 acggtcggta cttccacttt gatgatttca gcaccgctga tttcatctgg catttttttt
     9721 actgcttcat aggctggatt cactttgtcc ccaccaaatg gatcaaaacc tgttactagt
     9781 actttcatct gttgttcctc cgtccgattg atttaacata tggttatctt ttatcatacc
     9841 attttccttg aacagcgtaa ataaaggaaa caatagttta aataacataa cagatcaaac
     9901 ttaatatatt cttataaaaa aatagtgttc cactacaatg ttagaagagg ttgcgacaat
     9961 tattctgtca caacccctct cttctattat ttaaatagaa tcatataagc aatttggaaa
    10021 actagcataa ataacgcaat aaacaactgg tttttgatca ctccgtattt gtctttcatc
    10081 tccagcatcg ctacaggcac gatattgaag ttagcagcca tcggtgtcag cagggtccca
    10141 caaaaaccgc aagtcaatgc aaccattcct attaacgctg gattcgctcc atgactaaat
    10201 acgaatggtg caccgatccc aaccgtcatc acggtgatgg ccgcaaatgc attccccatg
    10261 attaccgtaa atatcaccat gccaagagcg taaatgatga tgccgatgtt cacatttcct
    10321 tctggaacga tcgtacctac tgcattggaa atcactgtcc caactccagc gcttgtaaat
    10381 accgcaccta gagaagctaa aagcattggc aacatgctta acggccctac tgtgcccagc
    10441 atatctgctg catcatctaa aaatgtactt ggtcgattat ctcgagaaaa gaacatcaag
    10501 attagcatgg ctgcaaaaac accgacgccc acgccgacta aagcacctaa attggtaaat
    10561 agagcaaaca agatcgcaaa gacaccgata ctcaaagctg gaataaaaat tttcattcct
    10621 agtttgtctg acattttttc catatattct tttgatggaa gccggctttc tcctttgctg
    10681 actttcttag caattgctgg tatggtcatc gcaaagatca agccaccgtt cacgattgcc
    10741 ggaagccatc ttcctcctgc aataactacc cctaagaccg tccagaaaaa ggctgaccca
    10801 taacgatgag gattggtttt atctgttaaa tttcttactc cagtgtaaat caatacgagt
    10861 cccatcacga tataaaggat ctccagtaat ttatcgccta ataaaatatc aggatttgta
    10921 aaaaagtcca tcttattgcc cctttcctgg ataatatttc ttcgctaatt tcttttcttt
    10981 aagatagaag tagacacttg ccacaactaa agccgtgata gccactggaa cttccactaa
    11041 agcaagctgt cccaatgtta cgtcatatcc tagatctttc agtgttgatt ggactagcaa
    11101 cgcccctgct cctccgatga atagtacttg gccaaagaac cagcagacat tttccatagc
    11161 tgaagccata ccttttagtt cttcttcatg cttaggatgg acttctaacc cttttgattc
    11221 gatggtcccc aatgccatcg gtaaaatgat tggacgaaca aatccagcaa ctccaccaaa
    11281 actcacgtta aaagccgcaa agatcattcg aaagatccca taaatatcta caatcatacc
    11341 agcagatact ttcttgaatc gcttgatcaa ggaagccgct gattctttca gaccatttct
    11401 ttcaagcgtt cctgttgcca acataatgat gataaaaatc gccatcccgc gattgtttac
    11461 aaaacttgta cctaaaagtt ctaacattcc ttgaatgcca agaccgccag tcaaagctgt
    11521 aacaactaaa gcaaccatta cgatcaatat cgagtctaat ttaaatgcaa acccgagaat
    11581 aacaatcaag acgcctaaaa ggctaagata attttccata tattttcctc cataaaatga
    11641 caatattttt ttaattataa agcaaaacac ataaaaaata tagttgtttt ctcacgaaat
    11701 agacactatt tttaaatatt tttcgttatt tttttatcac aaaaattatc ttacttattg
    11761 taaggtaaag ctttttttaa tt
//
LOCUS       DAJSMK010000072        11519 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.075, whole genome shotgun sequence.
ACCESSION   DAJSMK010000072 DAJSMK010000000
VERSION     DAJSMK010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.075"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(75..2150)
                     /locus_tag="ON488_001997"
     CDS             complement(75..2150)
                     /locus_tag="ON488_001997"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HCR3232185.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDYEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTYHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDADRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2152..3069)
                     /gene="glyQ"
                     /locus_tag="ON488_001998"
     CDS             complement(2152..3069)
                     /gene="glyQ"
                     /locus_tag="ON488_001998"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HCR3232186.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(3455..4267)
                     /gene="recO"
                     /locus_tag="ON488_001999"
     CDS             complement(3455..4267)
                     /gene="recO"
                     /locus_tag="ON488_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HCR3232187.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKDMSEKDLPKKEE"
     gene            complement(4410..5309)
                     /gene="era"
                     /locus_tag="ON488_002000"
     CDS             complement(4410..5309)
                     /gene="era"
                     /locus_tag="ON488_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HCR3232188.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5324..5719)
                     /locus_tag="ON488_002001"
     CDS             complement(5324..5719)
                     /locus_tag="ON488_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HCR3232189.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIVGLILFVPKIYHLLFN"
     gene            complement(5703..6179)
                     /gene="ybeY"
                     /locus_tag="ON488_002002"
     CDS             complement(5703..6179)
                     /gene="ybeY"
                     /locus_tag="ON488_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HCR3232190.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6208..8400)
                     /locus_tag="ON488_002003"
     CDS             complement(6208..8400)
                     /locus_tag="ON488_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HCR3232191.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLFAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(8424..9395)
                     /locus_tag="ON488_002004"
     CDS             complement(8424..9395)
                     /locus_tag="ON488_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HCR3232192.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10101..11480
                     /gene="brnQ"
                     /locus_tag="ON488_002005"
     CDS             10101..11480
                     /gene="brnQ"
                     /locus_tag="ON488_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HCR3232193.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGTNWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
BASE COUNT         3096 a         2462 c         2117 g         3844 t
ORIGIN      
        1 agttatttat aacaaataaa ccagagaaat agcctatttt gtgcctgttc tctggtttat
       61 ttacatatta gaaattattt tgtgatgatt tgatctaaac ttgctagtga caaagccatg
      121 gcagcaattt gacttaattg cgttaatcgg ttcttacgta ctgctggttc ttctgccatg
      181 accatcgtct gatcaaaata attttcgatc agtgggcgaa ggcttacaag ctgatcataa
      241 ttttcgttga tcgtttggtc agcaaagctt gttttcattg cctctactgc tttgtgcagt
      301 tctttctccg cttcgttttc gaacagttca gggtctactt ctgattgttt ttcaagctcc
      361 gcttttttcg ctaagttcac gacacgtgtc aaagcttcca tcgatggttt gaagtcttca
      421 tctgcaagat gctgcttgaa caattgtgct gctgcaaata cttttgtcag atctttttgt
      481 tctgcattca aaacagcttc gatgacatca tgacgaatat tcttcgttgt caataattgg
      541 cgcagacggc ctttgataaa gtcgatcacc tgttgttgtc ccgctgacaa gccaatgcca
      601 aaacgatccg catctttact gataacttca ctaatcgttt cttgcagaac agataaagga
      661 aaggcccatt ttttcgattc gatgattcga acgacaccat atgcttgacg gcgcaaagca
      721 tatggatcgt ttgagccact tgggatcatc ccaactgcaa agaaagaaaa gatactatct
      781 aatttatcag caatcgctaa aacagaacct actgtagtct caggtagatc tccttcactg
      841 gatataggca tgtaatgttc acggattgct gttgctacgg ctggtttctc gcctttaagc
      901 agagcatatt tttctcccat gatcccttgt agttcaggga attctcctac catgttggtt
      961 actagatcaa atttatagat ttcagcagcg cgttgcagat ccatcaattc ttcctcagat
     1021 agtcctactt gctcgcctat gatgcgggcg atgacttgta cccgttgcat tttctcgtag
     1081 atgctaccga ttttttcatg gtaagtaaca gtttttaatt tttcaacgta ttggtcgatt
     1141 gaagctttct tgtcttcatt ataaaagaat tccgcatctt ctaaacgagc agtcaatact
     1201 ttttgattgc ctcgaaccac attttccaat tttacccgat caccattacg agcagaaata
     1261 aaatgaggaa gcagcatacc ttgatcattc cgtacctcga aataacgttg atgttctttc
     1321 atagaagtga ctagtacttc ttcaggaaca gaaagatatt tttcttcgta gtcgccagaa
     1381 aagacagttg gatattcgac taaattgttg acttcttcta gtaaatcttc gtctagatca
     1441 ataacccagt gatttttttc tgctaattcg tttgcttgtg taacgatcat ttcttgtctt
     1501 ttttgcggag acgcaatgac gaattgttca ttcaattttt cttcatattc ttttgcatgc
     1561 gcaaatgtca catcttcgcc taagaaacga tgacctcgag aggctctgcc tgttttgaca
     1621 tccaagattt cgaatgggat tacttcatca tctaacaatg ccacgatcca gtgaataggg
     1681 cggatatatt caaaatcgta ttctgcccaa tgcatcgtta cagggaaagt caggctttta
     1741 atgacatctg ctaaacctgt caatacttct ttggattcct taccatgagt gtatttcgtt
     1801 acatagacat attccacacc ttttaattct ctaaaagtga tagcgtctgt cgtcagacct
     1861 tgtccgcgga caaatccttc cgctgctttc gtccagtttc catctgcgtc caaagcaatt
     1921 tttttggctg gtcctttgac ttcttcttca ctgtccgctt gtcgttctgg aatatttgtt
     1981 actttgattg ctaaacggcg cggtgtggaa aatgtttcga tcgtatcata agtcaattgg
     2041 ttttcatcta aaaattttgc tgttttttct tctaattgtt tcatgcttgg tgtgacaaca
     2101 tgggcaggca tttcttccag cccgatttca agtaataagt cttttgccat cttattcagc
     2161 ctccttcacg gtttctggat ttgctgtgtt tttattcaac aaagggaatc ctaatttttc
     2221 gcgttctgcc acaaagattt tggctacagc acgagccatg ttgcggatac gggaaagata
     2281 accggcacgc tctgttacgg atactgcacc gcgagcatct aataaattga atgtatggct
     2341 gcatttcaaa atataatcat acgctggatg aacaagattt tcatcgatac agcgtttagc
     2401 ttctttttca aaacgatcaa agttgcttag tagcaagtct tgatcgctta cttcaaaaga
     2461 atatttggaa tgttcatatt ctggttgttt gaagatctcg ccatatttca cgccatcagc
     2521 ccattctaaa tcatagacac tttcaacttc ttggatataa gaagcaagac gttctagtcc
     2581 ataagtgatc tcagaagtga ctggtttaca aggcagtcca ccaacttgct ggaagtacgt
     2641 gaattgtgtg atttccattc cgtcaagcca tacttcccaa cccacaccgg cacagcccat
     2701 ggatgggttc tcccagttgt cttcaacaaa acggatgtcg tgttctaatg gatcgattcc
     2761 taaaaggcgc aagctttcta aataaagctc ttggatattc tcaggtgaag gtttcatcac
     2821 gacttggaat tgatgatgct gatacaaacg gtttgggttt tcaccataac gtccatcagc
     2881 tggtcggcga gatggttcta cgtaagcagc attccatggt tctggtccga ttgcccgtaa
     2941 aaaggtatat gggctcatcg tacctgctcc tttttctgtg tcatacgctt gcatcagcat
     3001 gcagccgttt gatgaccaaa atttttgtaa tgttaaaatc atatcttgga cggtcaattt
     3061 tttactcatc tgttttgccc ctttcaattt taaagcgttg ctgtcaaata agaatacagg
     3121 aaagaaaacg acaaaaaatc cctatgtctg attacagaca tagggacgaa taattcgcgg
     3181 ttccacccta cttccgaata aagattcggc agcttcattt atcgtactcg caagtgcctc
     3241 ttcaaaaatc gtttgggtcc ggctcccact ctcccgaact cgctaaacca cgtgtttttt
     3301 actgatcttg gtcaatgtac gtattcattt tgcagttttc ttgtttctat aatagatcct
     3361 ctcactgaac gatctatttg atctacggtt aataatagac ggaactccct gtgtttgtca
     3421 aatggttttg attttttgtt gtatgtttca tttactattc ttctttttta ggtagatctt
     3481 tttcagacat gtctttctct ggcgtcttta atacgtgtgc ccaagacttc atttgatcga
     3541 tgaacttttt gcttttcaaa tgaataccga catattcatc atacagctgg tcgatgagtt
     3601 cacggattgc ttgtttggtt tcttctttca gatggattcc actgatttta tcataagaaa
     3661 tagctgaaaa catccgaacg aaataaacag ctcgaggatc tgcatgataa cggtgatcgt
     3721 ccatcgacca atgtctttcg catatcacac caccatattt ggaagaatag tcaaattttc
     3781 cttttgtttc cccacatacg acgcagtgtg tccagattgg tgcaattccg aagcgttgca
     3841 gtatttgaac ttcaaagata ttcgtgatga tttctgcatc atctccttga tccatccgct
     3901 gcagagcttg ttgcgtaaat tggaataaat gcgggtcata ttgatgatct tcgattgctg
     3961 catctactag atttagcaaa taggtaccat aaccgctcaa aaagatatct tcttggatgt
     4021 tccgaaacgc atggacgtct ttgacactgc ttaaaaacga caaaccttca cttcgaaaat
     4081 taccgatata gactgcttcg gtaaagggga gcaaagccgg agctaatggc tgattttgcc
     4141 gatggattcc tttgatataa aacatcattt tgccagaaga ttccgtaaag attttgacta
     4201 atttatcttt ttctttgtaa ttacggctag ataaaatcaa gcctttcgat tctgcaagct
     4261 ggctcatatt ctccctccta aaaaataaat ctggaaaagc agattctgcc gatccagatt
     4321 atttatgttt cgatcttccg ccgtttttct caacgtgcgg atttttatcc agtttatttc
     4381 tatacttaac ctataagaag ttcagaatat cagtattcat cttttcggta gccgaagtct
     4441 tgcagataga cttttttgtc tcgccagtct ttttggactt tgacccaaag ttctagaaat
     4501 actttgtctc ctaaaagatt ttcgatatcc tttcttgctt tcgttcctac ttgcttcagc
     4561 atttttccgc ctttgccgat aatgattcct ttttggctat ctctttcgac gatgatcgtg
     4621 gcctggatat ggattttatc attctcgttt cgcttcatcg aatcaacaac gactgcgaca
     4681 gaatgaggca cttcgtctcg tgttaaaaac aagactttct cacggatcaa ttcagaaacg
     4741 atgaagtatt caggatgatc agtcacttga tcatctggaa aatattgtgg gccctctggc
     4801 atttcactga ctaatacatc catcaaacgt tcgacgttgt ttccttctgt agcagaaatt
     4861 ggaatcactt gtgcaaaggg catctgcgtt gaataatctt cgatgattcc caacaactcg
     4921 tctggatgga ttttatcgat tttattgata atcagataaa caggagaatg cacgtttttt
     4981 agacgttcaa taataaaatc gtctccccgg ccgcgttttt gatcagcgct gatcataaat
     5041 aagaccgcgt ccacttcttt caacgcactg taagctgctt ctaccataaa atctcctaaa
     5101 cgatgctttg gtttatggat tcctggtgtg tcaataaaaa tcaactgagc ttctggtgta
     5161 gtatatactc cttggatttt atttctagtt gtctgcgcct tatcactcat gatggcaatt
     5221 ttttgaccca cgattcgatt caataatgtg gattttccta cattcgggcg gccgacgatt
     5281 gcgacaaacc ctgatttatg ttctggcata tacgttctcc tttttaatta aacaacaaat
     5341 gatatatttt agggacaaat aaaatcaacc caacgatgac ggcaaaacaa gcggtcacta
     5401 aaactgctcc agctgccata tctttgattt ttttcccaat cggatgaaaa tgaaaatccg
     5461 taaacatgtc tacgacattt tcaaaaacag tattgatgat ctctactatc catacgagaa
     5521 aaacagctaa aagcagccat aaccattcta tccgatcaag ttggaaaatc acgcccataa
     5581 acaaagcgag gattccgaac gcaacatgtt tcctcatgtt gcgttcttcc tcaaaaacag
     5641 ttttgactcc ttggacggca aattccacgg acatcaggaa atgtttgttt ttctctacgt
     5701 ttttatcttt taagtccata ggcatctaag atctctttct gtaaaccaaa catttctttc
     5761 tcatcctctg gtgtcatatg gtcatacccg ttgatatgca agaatccatg aaccgctaaa
     5821 aagccaagtt cccgatcata cgaatggccg taagcttctg cttgctctgc agcacgttca
     5881 gtagagatca tgatgtctcc cagtacacga ggcaatggat tctctccatc ttcaaaaatc
     5941 actgggattt cgtcttcacc ctcttcttcc aaggcaaaac tgatgacgtc tgtcggtgca
     6001 tcttttccac ggtaatcacg attgattact tggatcgctg cgttgtccat gaaagtaaca
     6061 gacatttctg tttcttctgg caactctaaa tatgatgctg caaattgcaa caagtcgtcg
     6121 atttctttca ttttctcttc tgagacttgg tttgtttcat ccatgaaggt aatatccatt
     6181 atacatcgct tctttctatt cttcttgcta ttcttcttgt tcttctttta tcttctcaac
     6241 ttccgatttc attttaggat atttgatccg agaatggaag gtactgctta aaccgctgat
     6301 caatgatttt tctactttac ggatttcttt taacgtcaat ccactgtcat ccaattgtcc
     6361 atcggaaata cgctcttcta taagattatg gacaaaactt tcgatttttt cgcttgttgg
     6421 atggtccatt gcccgtactg ccgcttcaca actgtcagct atattgacga ttcctgcttc
     6481 acggctttga ggttttggtc caggataacg gaattgctct tccgtgactt ccgggttgcg
     6541 ttcctttgcc ttaacgtaga aataacgcat cagcgtggtt ccatgatgct gtctgcaaat
     6601 atcgatcacc atttgcggca tattataatc ttccaatatt ttggcaccat ctgtcacatg
     6661 tccaaagata atatgtttac tgtcttctgg caataagaaa ttgtgcggat tttccgctcc
     6721 tgaaggcaag ttctcaacga aaaagctggc gtgtttgatc ttgccgatat catgataata
     6781 gcaagctact cgagttagta aagaacgtcc accgatttct gctacagcat tagcacttag
     6841 attggctacc atcatgctat gatgatacgt acctggtgct tcttctaaca actgtttcaa
     6901 taaagggtga ttaggattgc tgagttcatt taatacgatc acactatcat cattgaccat
     6961 caattcaata taggggtgca gacctatcgt cagcaagaat gagaacaatg cacctgtgaa
     7021 tccgcagact agcgttaacc aagtcgttgc atccccaaag ctcattcctt ggtagataat
     7081 caaaatgaca tccatcatca cagggaaaat aatgacccac atagcagcga ataacccttg
     7141 ttctgagatc cgtttgcgtc tgacgatcgt tgccatgaga ccagaaaata cataggacat
     7201 caaaataact gtcagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac
     7261 tgcttggaaa ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag
     7321 tggagcaaaa gccgcggggt aaaacagcgg aatataagca gcttgttctg tttggaagag
     7381 ttggaaaaat ttcattagta ctacgctgac tgacattgct gtcacgtaga aaagtacgta
     7441 ttttgttctt tctcctgcat tttgaaattg aagtgaatta taaatcagta caccgatttg
     7501 aagcaaaaca gctaaaacca tggcaatgag tgggaaaatc gaagtcgttt gattcgtcaa
     7561 tcctagtaat tccaattttt tcatcgctga agcatcaatt tgatttcctt cgcgaacaat
     7621 gatttctcct tggaagatca tcactggttg tacagcttct cgtgcagatt gttttaattc
     7681 ttctgtcttt ttctcattca atacatcatt gactacaatg ccttgatcca ctaagtagcg
     7741 gatcatttgt tgctgctctg ttgtgacatt caaatactga atctgatctt ctgcttcttg
     7801 tttaaaagct tccaattcgc tttcacgaac ttgtttactc atctgttcgt caatgagctt
     7861 caaactttca tccctaaccg tgtgaatttc cgtttcagtc atttcaaata tcgtcgaata
     7921 aaaattgttc ggcagttttt ggtaaaacgc aacgttttct gcattcacgt tttcaaaatt
     7981 tttcttcagt gtagcaatcc gctcttctgt agtaggtttc gggatatttt catcttcctt
     8041 cgccttatct accttgtcat tataagattt gttgatggta tcattcgtct tatcgatcaa
     8101 ttcgaataat tgcttgatcc gattgttctg gtcatctgcc agatcttttt gataagtata
     8161 ttctggagtc actgcttctg ctgctagttt tcttctttgt tcggtttctt ccgtgttctc
     8221 gatcgtttta ttcgcacgga tactctcttc tgctacttgg ccttctctaa aatcattggc
     8281 cttttgtttg acactactaa atgtaacgcc gcaaacaatg ataaaaaaca agaacagaag
     8341 gaaaggcaat gctgcctttc cgagtttttc ttgtagtttc tgcagtgttt tattcaacat
     8401 gtgcttatcc tcctaagcaa agcttattct tgatgaagat ccgccttttc ataagctttg
     8461 atgatttcgg caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg
     8521 atttttttga tttgctttag tgttcgttct gcatgaacaa gaccacttgt cgtccctcga
     8581 ggcaagtcta tctgacttgt atccccattg acaatcattt ttgattgata accgagacgg
     8641 gtcaagaaca ttttcatctg agcgactgtc gtgttttgtg cttcgtccaa gataacgaat
     8701 gcatcatcca atgtccgccc ccgcatgtaa gctaatggtg cgatttcgat tacgcctcgt
     8761 tccatcaatc ggttcgtatg atccaatcca aaaatttggt ataaagcatc ataaacaggc
     8821 cgcagataag gatccacttt ttctttcaga tcccctggta gaaagcctag gttttcccct
     8881 gcctctacag cgggccgcgt caaaatgatt ttttgcactt cgcctttttt taaggcagca
     8941 attgctaata ctacggcaag aaacgttttc cctgttccgg ctggccctac accaaatacg
     9001 atgtcatgtt tggctaccga ttcaacatat ttcttttgac cgctgttttt tacccgtata
     9061 ggttttccat tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat
     9121 gtaccttttt gccccatttt caatgccgtc acaacatcgg gcgtacttac gtggattcct
     9181 cgtttgatca attcctgtaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt
     9241 tcaccaatga tctgaatgat ttctccacgt gtatggatgg ttgtttccgt tgtttcctcg
     9301 atcagtttta tatgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagctgtc
     9361 aatctaatct ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat
     9421 tcattctttc ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttgt
     9481 aaaagagtcg tttaaccata cgtaccaaga aacgttaaaa aatagccgtt tccattcgct
     9541 aaaggtctcg ttttgataaa aagaatctga gaatgtaagt tatatgaaag tggagaacaa
     9601 aatattccgt ttcattcagc aggtattctc taggtatttt tcttgtttca aaaaaagaaa
     9661 acaaaatagt taaaatattc ttgcatttca aaaaaaacag gtgtattatt acgtcaacaa
     9721 ataaacatac agcaaagcgt cgaggaaaac agtaggctat tcaacgattt attcccagtg
     9781 agtcatgtaa gtgagaaatg acaataaatc gaatagacga acatcatttc cgagtcaatg
     9841 tcgaaaacgt agatcattgt ggctgcctcc attatcaggc tagcggataa ctttatcaaa
     9901 aagcgtccgt gaatgaagaa gcttttttaa gcgaaaaaag gtggtaccgt tctagaatct
     9961 agagcccttt tcccaagtgg aaaagggctt tttttatatt ttaaggtggt ggttttcatg
    10021 gaatctgata ttaatggcat tactaattgc tgcaacgttt atatcgtcaa tcaaaatgat
    10081 aattattgga ggaaaaattt atggaagaaa caaaaactta ttcatggaaa caactattga
    10141 tggtcagttc acttatcttc gggatgttct tcgggtcagg taatctaatc tttcctgtcc
    10201 acttaggtca aatggctggc acaaactggg tcagtgctgg cgtaggattt gccatctcag
    10261 gcgctctttt cccattacta gctatcttag ctgtagtagt gacaaaaagt gatggtctgt
    10321 atgacttagc taaacctgtc ggaaaatggt atgctgcctt gttcttaatc cttgttcatt
    10381 tgacgatcgg accatttttc ggtacaccac ggacagctgc tactgctttt gaaatggctg
    10441 ctaaaccatt tttgcctgaa aaatataatt cattaggtat gtttttattc tctgctcttt
    10501 tctttttact tgcttatttc cttactgtcc atcccacacg gttggtcaaa tacgtcggaa
    10561 agtatctaaa ctccttgttt cttgcattat tagcaatcat ttttgtcgtt tctttattcc
    10621 acccaatggg aaatctaaat caatctgctg cagatactta ccaaacaaac gctttaacaa
    10681 atggtgtcct agaaggttat aacacggttg atgcagtagc tttgcttgcc ttaagtgtca
    10741 cttttgtcca tgcagtccgt gaccttggtt tcaaagataa aaaagtcaca gaattaacag
    10801 caaaagctgg tagcctgagc gttgcgctag aagtcatgat ctattttgga cttgttcttc
    10861 tcggtgcgat gagtttgaat aagatgtctt tatcagaaaa tggcggaact gcactttctc
    10921 agattactaa tttttattta ggtaacttcg gcgctagctt cttaggagtg atggtcacat
    10981 taggtgtctt cactaccgct atgggactcg ttgtttcttt tgcacaagat ttccataaac
    11041 tgttccctaa agtcagttat atgacatggc tgcggttaac gactttcgtc tcttttgtcg
    11101 ttgcaaatgc tggtttggac aatatcatcc aatggtcttt accagtattg atgcttttgt
    11161 acccattgtc gcttgcgttg atcttgcttt ccttaacagc aaaatttttc caaaagacac
    11221 catttgtcta tcaagtaacg atgttgtttg ctgctgttcc cgccgtattg gatatgctgg
    11281 caaattcgcc tgctttagtg agtcaacaaa gagttgtagc aagcatgctc gaattttatc
    11341 atcatcacgt tccttttgct gcattaggac ttggctggat ggtcccaacg ttacttggtt
    11401 acgctggcag cttactcttc tattacgcct atcgcctatc agggtacaaa caagaagcaa
    11461 atgaactacc agaagaataa ccagatcaaa cacaatttaa cataagaaat attaaacag
//
LOCUS       DAJSMK010000073        11487 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.076, whole genome shotgun sequence.
ACCESSION   DAJSMK010000073 DAJSMK010000000
VERSION     DAJSMK010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.076"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            5..2377
                     /locus_tag="ON488_002006"
     CDS             5..2377
                     /locus_tag="ON488_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232194.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="ON488_002007"
     CDS             2438..3898
                     /locus_tag="ON488_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HCR3232195.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVRDDRLDHAVAFLWKDPQTNETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKVI
                     YEEVAKEEKITPEAIMAIHKTENNLQLTNQLVSAHKVNASFGQQLSVNDSIEAINLKD
                     ICREVAKELKACERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /locus_tag="ON488_002008"
     CDS             3909..6113
                     /locus_tag="ON488_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HCR3232196.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="ON488_002009"
     CDS             6129..6278
                     /locus_tag="ON488_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232197.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6354..6947
                     /locus_tag="ON488_002010"
     CDS             6354..6947
                     /locus_tag="ON488_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HCR3232198.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6960..7859
                     /locus_tag="ON488_002011"
     CDS             6960..7859
                     /locus_tag="ON488_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HCR3232199.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7862..8347
                     /gene="ssb"
                     /locus_tag="ON488_002012"
     CDS             7862..8347
                     /gene="ssb"
                     /locus_tag="ON488_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCR3232200.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(8488..8691)
                     /locus_tag="ON488_002013"
     CDS             complement(8488..8691)
                     /locus_tag="ON488_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HCR3232201.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            8766..9026
                     /locus_tag="ON488_002014"
     CDS             8766..9026
                     /locus_tag="ON488_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232202.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9463..9669
                     /locus_tag="ON488_002015"
     CDS             9463..9669
                     /locus_tag="ON488_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HCR3232203.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            9669..9920
                     /locus_tag="ON488_002016"
     CDS             9669..9920
                     /locus_tag="ON488_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232204.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            9935..10372
                     /locus_tag="ON488_002017"
     CDS             9935..10372
                     /locus_tag="ON488_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232205.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            10365..11072
                     /locus_tag="ON488_002018"
     CDS             10365..11072
                     /locus_tag="ON488_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232206.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
BASE COUNT         4312 a         1931 c         2399 g         2845 t
ORIGIN      
        1 ggacatggca gaagaaaaag aaccactaga caatagtcgc ttgggaaaat ccaaaagaaa
       61 attagtacga ttgcaaaatg aattaaacga acaaattgag aagatgtttg aacaccagag
      121 aaagaccaac ggtcagccaa tgaacgataa gagaaatggg cattcttggt ttaggcaaca
      181 agaacgttta gaaaacaaag tgcatagtct gagagaagag atcaagcaac aagaaaaaca
      241 ggtagaaaaa cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 cctggatatg acaatcgaaa atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg actttttcag ccgctacgat ccgaaaatac caacggaaat tggaaacatt
      421 agaacagctg aaagaaagat cagaaaaagg aaaagaaaat cttcttcctg aagtacaagc
      481 aattattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 agactatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctgc
      661 gccaactgat tctttgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tagaattgat
      781 cgatcaactc aaaacgttgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaagaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccca tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 aaaggaacaa aaacaaacgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaagcaaga
     1081 agtcaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtgaaa gaacttttga attttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ctgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actacacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgggg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cttcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 ggcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctgtagaaac ggcagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtga ttttaaaagg
     2221 aaaaagttat ggaaaagaga ttcaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg aaacagtgtc agaagtggcc aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg cgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg tttgaaaatg accgaaaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagact atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ctctaagcaa caatttaaag cagccacaga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtagaa aatcttcatt ttgagacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaac atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaat gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagttaaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctaaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtttcga tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagttga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaagtcattt atgaagaagt cgcaaaagaa gaaaagatca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaat tggtttccgc
     3541 tcacaaagta aatgcgtctt ttggtcagca gctttctgtt aacgattcaa tagaagctat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagcttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggatt ggaatgatca attgaagcat gaaatctacc aacaagagat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggtaga cagcaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaaaccgtc acaagcgaag gcttatgccg
     3961 atagcttttc taaagctacc cgaaaagatg ggtattttga gatccaagat cgattgtttt
     4021 caggagaaac tgtgatcacg tatggttttg gtcatttagt cgagttagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagagcattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatagctt
     4261 ggacgatcat tcaacaagca ggcgccgatc atggaaagat atttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagat gcagaagaga
     4381 cctacccaaa atttgaagaa gcacaagcac gccagatcgc cgattggttg atcggcatga
     4441 acggtagccc gctgtatagt ttactcttgc agcaaaaagg cataccagga agtttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attacaggaa aagattagaa
     4561 acttccaaaa agaaccatat tttgaaggaa aagcccaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggtac gatccaccaa gttgaaaccg
     4741 agaaaaaaag tgcggcaagt ccacgtcttt tttctctatc cagccttcaa tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagata ctttggaagc catgcaaggg ttgtatgaag
     4861 ggaaatatct aagctaccca cgaacagata ccccttatat tacagaaggg gagtatgcgt
     4921 atctgttgga tcacttagac gaatacaaac actttttaaa ggccgaagcc attcctactc
     4981 ctattcatac accgaatagt cggtatgtga ataataagaa agtccaggaa cattacgcga
     5041 tcattcctac aaagacggtc atgacggcag cggcttttga acaattaagt ccactgcagc
     5101 aggctattta tgaacaagtg ttaaaaacaa cggtggccat gtttgcggaa aagtatacct
     5161 atgaagaaac aacgatcttg acgcaagttc agcagcttca gctaaagaca gtcggaaaag
     5221 taccagtaga tctaggttgg aaaaagctgt ttggcaaaga gagcgacaga aaagaaaagg
     5281 aagaagaacc gctacttcct aaagtgacaa aaggagaagc ggtgacggta gatctacaag
     5341 tccttgaaaa agaaacgaag ccaccacaac cttataccga aggtacgttg atcacagcga
     5401 tgaaaacagc tggaaaaacc gtggatagcg aagaagcaca atccatattg aaagaagtag
     5461 aaggaatcgg tacagaagca acacgagcaa atattattga aactttgaaa caaaaggaat
     5521 atatcaaggt agaaaaaaat aagcttgtgg tgacaaataa agggatttta ctttgccaag
     5581 ccgtggaaaa agagccgctg ctaacaagtg ccgaaatgac cgccaaatgg gaaagttact
     5641 tattaaagat tggtgagcag aaaggaacac aagctacttt cttagctaat atccaaaaat
     5701 ttgtctctca cttgttggaa gtcgtaccgg gacaaatcca gtcaacagat tttggatcaa
     5761 cgttacaaga ggtgaaagca gccagtgaaa aacaggaagc aacgcgtcat ttaggtgttt
     5821 gtccaaaatg tcgggaacaa gaagtcttgc tttatcaaaa tgtggcggca tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gccacacaac
     5941 tgaaagagat cattcaaaac ggccgaacaa gccaatcagt cagaggacta aaaggtcaga
     6001 aaggttcgtt tgaagcaacg atcgttttaa aagaagactt tacaacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac tataagaaaa gaacacgccg cactacaaaa taatgaaggg
     6121 gttatcctat gcgaaataca acacacaaac aacaagaaat cgaaaatcaa aaagcaaaaa
     6181 ttcgtttaga acaagagaaa ttacgtgcaa ataaaagaag actgcaacaa ttaaagaacc
     6241 agcagcgcat tcaaaaagaa atcgaattag atcgatagac gttaatcttg ttacaaataa
     6301 actactatga tatatttgat gtagtgtatt tgtaacgaag ggaggggaag taaatgcaag
     6361 ataaactgaa agaattgttg gctattcgcg atggaaattt atctatgaag gaagccagga
     6421 aatttggaat cgcagcaacc actgtacaaa gattggtgaa tcaaggaaaa ttgatcaaag
     6481 ttgatcgtgg ttattatgta gaggatggtc atggaataga tgatttattt tggcttcagc
     6541 aacgattttc caggggaatc ttctctcatg aaacgacttt agatatttac cagctttcta
     6601 cgaatatgcc gaaattcatt cacttaactt ttccccatgg ctataacgtt gatcgttcaa
     6661 ttacaaaaga gcagcagtta caatttcatt tcgtgaagaa agaagtttat gaactaggaa
     6721 aagtagaggg aacttccttt caaggaaatc ctattactat gtatgataaa gagcgtacac
     6781 tttgtgatat ttggaatccg agatatgaat ttgaatatga aatgaaatta gaagcattaa
     6841 aagagtacat ggaagaccca ttgagagatc caagtaaatt aagagattac atgacaaaac
     6901 tacatgtaga aaaagaaatg aaataccaca tgcaaagctt atattgatgg aggaaaaaga
     6961 tgacaccgac acaatttgca gcaaaaacaa gaaatttagc aaagagtaca ggattaaatg
     7021 cacagttagt gcaacggcat tttatgatgg atcgtctaat tgaacaaatt tctgaatcaa
     7081 agtacaaaaa tgacttcatt ttgaaaggcg gctttttatt aggatcaaaa tatggaatcg
     7141 atagaaggac aacaattgat atcgatacga catttagaaa tagcaaatta actgaagaaa
     7201 aattgaagag catttttaat gatttaacta gaaaacccac aaaagaaggc attgttttct
     7261 ctattcaagg aatgaaggaa acaagagaag ccgattttta tcctggattt caaattaaat
     7321 tggtggctaa tttagagaaa gtacgtgtac cgtttaaaat ggacgtgaca acaggagatt
     7381 ctatttatcc tgaagtagat acacactatc accaattaat gtttgaagat aaaaaagtgg
     7441 agattccagc ttatccaaca gaacaaatta ttgcagaaaa gctaagtgct acgttcagct
     7501 ttggcacaga taattcgaga gcaaaagatt actacgactt atttaccatt ccgaaactag
     7561 aaaatatcga tacgaaagag ttatacaaaa gtgttcgaaa tacatttaca aaacgtgggg
     7621 atacaaaacc gttgtccttt tattatgaaa gagaaatgga taagatcaga ggaaatgact
     7681 atttggaaaa gcagtgggaa aaatatcgct cagttaacac gtttgcgaat tccatttcat
     7741 ttacagatac agtcaacgaa attgatcacc taatgaaaag tgtgatcaaa attgaaaatc
     7801 aagaaagaaa acggcagttt aaaagatcac aacaaatgaa tcaagaaatg gagagataaa
     7861 gatgatcaat aatgtaactt tagtaggacg cttaaccaaa gatccagatt tacgttatac
     7921 cgcgagtggt actgcagtag cgacttttac cctagctgtc aaccgaaatt tcacgaatca
     7981 aaacggcaat cgagaagctg attttattaa ctgtgtgatt tggcgcaaac cagcagaaac
     8041 gatggcgaca ttagctaaaa agggcagttt gatcggcgtt gttggacgga ttcaaacccg
     8101 aacctacgat aaccaacaag gacaacgtgt gtatgtgaca gaagttgtgg ccgataattt
     8161 ccaactatta gaaagtaaag cagcgacaga aagccgtgcg cacgctgatc aatcgtccag
     8221 cagtccaagc cctaccacct ttgaacaacg ggatgtagct acgcctaaca acaatggatt
     8281 gaacgcttca caaaatccat ttggcggaca atcaatcgat attagtgatg atgatttacc
     8341 attctgattg taaaagatca ataaagttgt tataatggat acgaaaagag gagttgcgct
     8401 aacaactccc ctaacagcac cgtttaagac ggtgaccagc ttaatattat ttttgaaaaa
     8461 taatcgtcga ccggctaaag ctgacggtta ttttttttga ttgttgttta caactgctaa
     8521 gattccaaaa atgattgttg cgatcaaaga accgaaacta atcattaatc ctagcgccgt
     8581 ttcaacaggc aaaaggcttc tcctttctgt aagattttgg aagtacgcac atacgcacca
     8641 cctcactttc aatcggatag ccaccgtcac aaactttact gtcttgatca ttatagcata
     8701 tctaaaatcg aataaaaatt ctcaatttta gctgtttttg ctataatttt agcgaggtga
     8761 tcgtgatgaa caaatatgtt ggtttgcttg ataaaatccg agtaataaaa acacaaccat
     8821 tattggttcg ctttacttta caaacaattc atgaatcgat taattgtgta gttgcagata
     8881 ttgaaattat cgataaattg ttaattatgg atgatggaaa atacaatatt gccgtcacag
     8941 gtcatttcaa taaacggaat caattagtca ttgaatcgat gcaaattaga aaccccgatc
     9001 attttacgcg atcgatgggc atataaaaga agagctgcag tcctaaatga ggattgcagc
     9061 tctttttgtt ttacatagaa acaggaaaag acctttttag gaagacacaa gtgccttctc
     9121 aattgaaaaa cctttctctc actccaaccg ccaccgccgt tcgagaagaa aggaagtgaa
     9181 cgttgcacgt tcactaagat atggtgtctt gcaaagcaag acaaaataga aaaaacttcc
     9241 tctcaccaaa aggttcgttc ctgttcgcta tctctttatt gatttgccag accggcaaca
     9301 agttgccttt tatcaccaaa aagcgacaag gacaagggta aatggcacgc tgcgcgccct
     9361 tgtccttgtc gcttttcgtt gattcattct ggccaacaaa tcaataaaga aagaactaac
     9421 gaaaggaaat aaaacctttc ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat
     9481 tattggggtg ttcccttcag cgaattattc ccaaactatc atgcaccaca tactgtcgaa
     9541 tgcgattgtg gagaaagagc gaaatgtatc aaaagctatc gtttgtatca atgtccaaca
     9601 tgcgggaaaa aatatacctt gtcttatggc gattatgttt tgattgatga gaaagtaaag
     9661 aaacggtgat gaaaacacaa cacaaattat tgactgtaaa agaagtcgtt caaattttgg
     9721 tggacaaaga agtcatttct gaaaaagtag cagaagcttt acttattccg cggtactgga
     9781 cgatagaaac ccctttagta gaggatgcac cgactatgct atttgaagac ctagtgaaga
     9841 ttgcaggata tgaactgcat tatcaagaaa acatggaaac ttatgaaatc gaatattggt
     9901 taaccaaatt agagaactaa aaaggagaaa aaatatggct caaaattact atgacgaatt
     9961 tgtcaaatta cctttggata aaatggcaca aaaaatggag gatatgacgt tcctatacca
    10021 tgaaacacgt gtacccaaaa aacattacaa ggaaaaattg tcagtcgcag tggaagaaat
    10081 gattgaatca ggtgtcgaaa tgaatctcat tgcgacgtac tatcgaacac tggaagaact
    10141 gaaaaaacaa aatggaaaat ggtttttcca agccttacta tgcttggaag taggtgtcaa
    10201 accaagcact atcaaacctt ccgaatatca agccttagaa ctgacttatg caaaattcgc
    10261 acagattaag aaagctaaag caatggctag cgactggcta gatacttttg aaaatatcga
    10321 aaaaaatggt gcattttata cgattgaatc ggaggagaaa gataatgaat aaggtggttt
    10381 atcagctaac aacagaagat gtttcgcaat ttttaacaaa caaagaacac ttgaatgaag
    10441 taatcagacg gattcaaaaa gactttagtt gtatggaaga aatgaagtac tttattcaaa
    10501 gagtggaaga acagttgtat atggaaagtg aaacgagtca aacgaaggtt acagtcagcc
    10561 ataatcgttt agacgtgtat aaacgtcgtc ctgacacatt aaaaaaagga gcggagcttc
    10621 tacgactaga aacagaaaaa tatatcatga atgtttacct agaaaggagt gagctggtcg
    10681 aaaactttgt cagctacacg atttgcagga aacactatta ctcagaatca gaatattatt
    10741 caatttttga gagcatggaa ttaatggaag aagaaatgga agagctaaac agcaaagatg
    10801 cgacggtaga cgattattac cttgtattta ctagattttt gacgtgtggg acggaatcta
    10861 tcgtgttaat gggaatggat tatgaactca ctgtacccga agcatttttg agggaatatg
    10921 tagaagaagt agataaccca ggcgacgact ggtacacgac tttaactgat tttttagaca
    10981 cctacactta cgacgataca gaagaaatcc aaaatgaact tgaccgtaaa cgaatgccat
    11041 atcaacgatt tgaaaggaaa aaaggtcaat aaccatttat accgaaaagt gaggatgtgt
    11101 gaaataagaa caaaaaacct tgaaattaag ggaatggttc ttatttcgca ccaatcgatc
    11161 caaccgcccc cgccgcttag gtggtgcgaa ataagcgggc aaagcccgat aacctaagag
    11221 aaagaaggag atccatatga ataaaatcat tcctctattg ttcgtactgt ttgttggcga
    11281 gatacttatg cgtcatggtg cagctctaca tttaaacttc gtagtattct taggaatact
    11341 ggtattttgt ttgatctttt ggcgctttgt gttaaccctt gtgagtctaa tattcaagtt
    11401 gattgcagcc atatttttaa tagggttatt tcgatgaaag gagagagtac taatgccaat
    11461 tgcaatagga aataaacggt tacccgt
//
LOCUS       DAJSMK010000074        11284 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.077, whole genome shotgun sequence.
ACCESSION   DAJSMK010000074 DAJSMK010000000
VERSION     DAJSMK010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11284
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.077"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            11..574
                     /locus_tag="ON488_002019"
     CDS             11..574
                     /locus_tag="ON488_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232207.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(635..979)
                     /locus_tag="ON488_002020"
     CDS             complement(635..979)
                     /locus_tag="ON488_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232208.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(1076..1321)
                     /locus_tag="ON488_002021"
     CDS             complement(1076..1321)
                     /locus_tag="ON488_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232209.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1391..1645)
                     /locus_tag="ON488_002022"
     CDS             complement(1391..1645)
                     /locus_tag="ON488_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232210.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(1809..2132)
                     /locus_tag="ON488_002023"
     CDS             complement(1809..2132)
                     /locus_tag="ON488_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232211.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2319..2392
                     /locus_tag="ON488_002024"
     tRNA            2319..2392
                     /locus_tag="ON488_002024"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2353..2355,aa:Ile,seq:cat)
     gene            complement(2777..3274)
                     /locus_tag="ON488_002025"
     CDS             complement(2777..3274)
                     /locus_tag="ON488_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCR3232212.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3314..4123)
                     /locus_tag="ON488_002026"
     CDS             complement(3314..4123)
                     /locus_tag="ON488_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HCR3232213.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4457..5314
                     /locus_tag="ON488_002027"
     CDS             4457..5314
                     /locus_tag="ON488_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCR3232214.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5307..6209
                     /locus_tag="ON488_002028"
     CDS             5307..6209
                     /locus_tag="ON488_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HCR3232215.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6242..6592
                     /locus_tag="ON488_002029"
     CDS             6242..6592
                     /locus_tag="ON488_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCR3232216.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            6641..7564
                     /locus_tag="ON488_002030"
     CDS             6641..7564
                     /locus_tag="ON488_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCR3232217.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            7642..8535
                     /locus_tag="ON488_002031"
     CDS             7642..8535
                     /locus_tag="ON488_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3232218.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            8573..9136
                     /gene="amaP"
                     /locus_tag="ON488_002032"
     CDS             8573..9136
                     /gene="amaP"
                     /locus_tag="ON488_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCR3232219.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9150..9338
                     /locus_tag="ON488_002033"
     CDS             9150..9338
                     /locus_tag="ON488_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCR3232220.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9351..10253
                     /locus_tag="ON488_002034"
     CDS             9351..10253
                     /locus_tag="ON488_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCR3232221.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10285..10527
                     /locus_tag="ON488_002035"
     CDS             10285..10527
                     /locus_tag="ON488_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCR3232222.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(10783..11154)
                     /locus_tag="ON488_002036"
     CDS             complement(10783..11154)
                     /locus_tag="ON488_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232223.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4002 a         1927 c         2134 g         3221 t
ORIGIN      
        1 aaaaataact gtgttatata ttaaaaaagg cataatagtt ataagctttt ttaaagaata
       61 tttagaaatt attaattttc gtctgaaaac aaaaaaagaa agcgttatta ttttagtcta
      121 ttttcagggg gggaacctta tgataaaaaa actattttta ctatcaatat taacgctagc
      181 aatggcaggt tgttctgact ctggcttagc aactgaactg atcacaaaat caactgaagc
      241 cacgacagag gagttaaaat gtggaaacga tcacagtgac tacagaggct taaatcgacg
      301 atgcatggga atattaggca gaagcaattg taagcatcga tgtagtaatc gaagaaggtg
      361 tagaagaagc aacagaaaaa tcaaaagaaa gatcaaaaga agcaatctgt gctgtgcatc
      421 gtatacagac gtcgaagatg cggtactttt aaaccacgtc aggagatgtt catttatgtc
      481 tagggaagtt ggcgatgaac caaaactaga gtacgctttt agttttgcac gtgaggatga
      541 agataaccct aaaacttacg acattttagc ttgatctaag atggttaaag ctttttaatg
      601 aagtaagagg agatagaagg cttttctagt tatattaggt aagataaatt cctttttgct
      661 ccaaatttgc taaacattct gctagataaa cttcatcgtg ttccggataa atcggcacgt
      721 tgcgctctac agtaggtaaa tcaaaaaatg cttcgcatga tttgccacga tacataggat
      781 ttttccactc tggtgctggg ctgtaaccac gtttttccat ttcatccatg acaagctgat
      841 gatattggaa taatctataa ggagaatagt gaaaaacata atccacagta gcatgtttct
      901 ttccccagcc atttcctctt aatgcacagc attcccgatg ttgtcctaaa agctgttgac
      961 gaggaagctt tgaaatcaat ttttcatgcc ataatcacat agaaatgtct cctttatata
     1021 tagattgtta accttagacg ttaaatgaaa aaaccagcac caaggctgga aaaaatcact
     1081 tcagtttgct tgctgtttct gagcgaccaa ttaggtaatc aacggaaata tcgtaaaagt
     1141 cagcgatata gattaattca atgatgcttg gaatttcttc tccttcttcg tacttacgat
     1201 atttgaataa aggaatactt aacgcgctag aaacagctac ttgagataaa gatcggccag
     1261 ttcttaagaa attcagacga caacgtaaag tatccagtaa aatagcttct tcgatactca
     1321 tttaatcacc tttcattata gtagaatagt tataatgact atagaaagct acacatgcaa
     1381 tcaatagtac tcaatgtttt ttatttaaac gtatcaaata aagaatgacg atcaataaag
     1441 acaaaaccag tcctgataat tcttctataa aaacactatc gggttcaaag tagttgtaat
     1501 taaaaacttt ccacataaag tagatagccg gaagagtcaa aatagctaaa taaaaccgtt
     1561 ctttgttcca attcataaga taaacaatac ttgcgaccag tgcgaccgca ggcacccaaa
     1621 acaaaactct caccaacgta atcatgtaac ggactcctca acgattcata taataaaaga
     1681 taacatgtta ttgcatacat cacaaatgaa atgctaggaa aataaaagaa gaatagatca
     1741 atgaaaaatg aaaaagcaga acagttttct gctgataagc aggaactgtt ccgctgaatg
     1801 tgtcttatct atcgagaaaa aatcaatgga ttgatatcta agtaattcaa tacatataaa
     1861 aagaggacga tcgcattcac taaaaaggaa agaatgatga tcccatagcg aatggaaaca
     1921 tatttaacaa atacttttgt ttgaatacgg gcatatcttt ttcctttata gctgagcatc
     1981 atgacaagaa gcaaaagggt aatcacacct tgaaaaatca ttccaataaa cagaattcct
     2041 gaggtttgat aatttaattg gagaaaataa gctgctgccg caactaaatc gaataaaatc
     2101 gcaataaatg gcaaaataat cactcctaac attgagaata aataaaagaa taacattttt
     2161 tctaaaataa gcaaataaaa attaaagtaa caaaatagtt atgacacaag taaaagaaat
     2221 aagaataaca atattatttt acttatattt tgaaacttgt gagagtttgt cattcgtgct
     2281 atagttgaaa agtaacaaaa ataaatttta tttatgatgt acctttagct cagttggtta
     2341 gagcagacgg ctcataaccg tccggtcgta ggttcgagtc ctacaaggta cataagaggt
     2401 tgtgaaaaag ctgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
     2461 tttttacttg gctgttctta ttactgcaga tgcaagcttt tgaataccgt ttaaggaaga
     2521 ggttgtgaaa tcagcgtttt gacctgagta ttagcttaac aaacggaaaa atagttcctc
     2581 atattttgcc gtttgttaag ctaataccga gggtcagctg attgaacacc atttaagaaa
     2641 gaggtcgtga gcctgccgtt tcactctgtg tcataaaaaa gccaatctac tttgatagaa
     2701 aaagcacgta ggactaaaac agttctgcgt gcttttttta ttgtgtgtta aatatcgtaa
     2761 atgaagatag atatttttat gattcgacga tagagacgtt gaaatctttc aacagctcta
     2821 aagcggattc tccgtgtttt ctactggaga ctaacattgg atcaacaaaa aagtctgctt
     2881 caggaaaagc actctgcagg cctatcagat tagagagtac acacaagttt gtttcaatcc
     2941 cgactacttc gatctctttt tgttcttctt tgctttcaaa taaagtttcc tggatttcag
     3001 ctaaagtttc aggtggaatc gtaaagtaat actttttaat cactcgttca ttttcttgtg
     3061 gagaaagaag agggatcaat tgcaaatctt ctcgttcttc ttctttgtcc ttcagttcaa
     3121 ctggtatatc ccgtgtgaag agaatatatt cattattttg gcgtgcttta gctaatcttt
     3181 gagcaatacg ttctgccaat tgatctgact ctggaatata aaattcgctg tttggatcaa
     3241 gaatatgatt ttgcatatca ataataacta acattttctt tcctcctaca ttcatatcgt
     3301 cattttattc tttttaatag aagtttttta aaatataagc aacaccagct tcttcattcg
     3361 tcagtgttac ttggtttgca atttctttta cttgtcgctg tgcattcccc atcgcaatac
     3421 tcaacccgct gtaattcaac atatcaatgt cgttttcttg atcgccaaaa gccatgatgt
     3481 cactcgattc gattccaagg taatccgcca gaaaaacaag tgaatgagct ttagtgatac
     3541 ctgtaggcgt gatttctaag aaatgcggat cagagaatac tgattggata ccatctgctt
     3601 gcagatctct ttgtagcttc tgtagttttt cttcactctt atctgttaat gctaatttaa
     3661 gatagctaag agaaggatct tccaacatat ttaaaatttg atcaaaagaa tggttctgta
     3721 aattgaaatg ttcataataa gggtcatctt tgactagatt tgattcatcg aatgtcagct
     3781 gatcatcttg ggtttctcgg ctagcaatga tggatatttt cgcttcttga gcatagaaga
     3841 aggcttttct cagtgtatcg ctatctattt ttgaacgtct gagaactttc gccatttttc
     3901 catccttcat ttcagcaatc agtgaaccat tggaagaaat caaatagcca ccgattccta
     3961 attcggaaaa aatatcttta gcagaaatgc tgttccttcc ggtagcgacg gttacgattc
     4021 cgccattttc atcaaatttc cgaagtgctt ggatattttc ttctggtatc tttccatttc
     4081 gatcaagcaa ggtaccgtct aaatcaatcg ctgctagttt cattttatct tcctactttc
     4141 tttttacata tctattttcc tgttacctta agattaaatg agaatttaaa aaaatgaaac
     4201 taacttgctt tgtcattatg aattttttca aaaaacattc ttaagaaaaa ggtggctata
     4261 tatagtagtt tttggtcaat acctttgaat aaaaagccat gaaaaacgaa tagttagcgc
     4321 ttaccgatgc gttttgtgat aaaaaaattt taaaatattc aatgaaaaca aagcatatat
     4381 tttgctttaa aaccaaatga ggaatattct agatgtagaa caggttagaa aaagattaga
     4441 aaaaggagtg attttgatgg agaagagata cggcgtagtt cctgtggtaa ctgcttcaga
     4501 cgaaaattat gctccttact tgagcgtgat gatcgcaact gcattagaaa attgcaataa
     4561 aacaagacgc ataaaatttt atgtgattga cgatggtcta tcagaatata gtaaagaagg
     4621 attggaagaa acggtaaata aatattcaag taatgcaagt atccaattcc tgacagtgga
     4681 aaaagatatc tacgaagact tcctagtcag tgaccatatc acaactaccg cttacttaag
     4741 aatttcttta ccaaacttat tagctaaaga ggattataag aaagtccttt acttagattc
     4801 agatgtgtta gtactagacg atatcgtaaa actatatgat gagccgttaa atggaaaaac
     4861 aatcggcgct attatcgatc caggccaagt gaaagctttg gaaagattag gaatcgattc
     4921 cgatgacttg tacttcaatt caggagtgat ggtgattgac attgatcaat ggaataaaaa
     4981 agaaattaca gaaaaaacta tccattacct cagtgaaaat ggcgatcgaa tcatctatca
     5041 cgaccaagat gctttgaatg ctgtacttta tgaagattgg gaacaacttc atccaaaatg
     5101 gaacatgcag acttcgctga tttttgaacg tcatccagca ccaaatgaaa aatatgaacg
     5161 tcagtataaa gaaggaaatg aaaaaccttc gatcgttcac tttacaggac atgataaacc
     5221 ttggaatacg ttgaaagatc atccgtatac caatttatac ttaaaaaaat tagcacacag
     5281 tactctaacg aaagtaggcg agatcaatga ataaaaaaga aatagcagta gtcgcaagtt
     5341 gtaacacaaa attcgtacca catttagctg cattatttgt ctcagtatta gataattgca
     5401 acccgtctaa atttgttcgg ttctatgtga ttgacgatga tatcgatttt gaaagtaaac
     5461 agcttttacg cttctcagtg aaaaacgcac gaatgaactc agatgtggaa ttcttgaaaa
     5521 tcaataaaga attctttaca aatgtggtaa tcagcgatcg tattccagaa acagcttatt
     5581 atcgtattgc gattccggaa ttgttccgcg gcacagaagt tgaacgtatc ttatatatgg
     5641 attgcgacat gatcgcttta caagatatct ctaaattatg gcgtcttgac ttcggtgatt
     5701 caatcgtagc agctgttgaa gacgctgggt tccatcaacg actggaaaaa atgaaaattt
     5761 cagctaaatc aatgcgttat ttcaactcag gtttgatgct gatcaatgtg aaaaaatggt
     5821 tagatgaaaa tattacgcaa aaagtattag atttcatcga acataatcca gaaaaattac
     5881 gattccatga ccaagatgca ttaaatgcta tcttacatga ccgttggtta ccacttcatc
     5941 cgcgttggaa tgcacaaggc tatatcatgg caaaagcaaa aaaacatcca acagcagcag
     6001 gtgaacgtga atacgaagaa actcgcaaca atccttacat tatccatttt tcaggacatg
     6061 tgaaaccgtg gagcaaggat tttgaagggc caacgaagaa atattacgaa aaatatgcag
     6121 ggatgacggc tttccgttgt gtagctaaat tccctaaata tccaaaatat gcaaaagttc
     6181 aaccaaaaac agatgtagtt gttaaataat agaagacaac aactgaagag ggggagtagg
     6241 aatggaaatt acaatgtcta aaaatgcagt agagacgtta attgaaaagg ttggggaaaa
     6301 tacaaaaatc gcactcgcgc ttatcaatga ttccgatcca tttctaaggg acaaaggtgc
     6361 ttttgcaaaa ggcagctttt ttcaaatcat tccttttgtt tcggaatttg gagaatatgc
     6421 gactaaaatc gagcatccat tattggacat ctatacatct aaattagagc aaaattattt
     6481 cggtaaacga ttgaacatgg acttcaacaa acagcttgac agcttttcat tagaaaatga
     6541 aatcgcagta ctcgattata atatcaaatt aaagaactgc ttcttcagct aatagtttcg
     6601 agaaagtcca aaaaggaggt atacattgag atactacttt gtggatgaag aaaagaatgt
     6661 aatagaaaca gatgaaaaaa aatataattg gctcgtactt gatagtgcaa agcccgaaga
     6721 gattgagcaa gcaatcgaag aattcgagct tcctgatgat attttcgtag gaaccgaata
     6781 tccggaagaa gtttctcgga tggagcgcct ttatgagacg aaactagagc atccattttc
     6841 tttggtagtg attaatctag atcagtcaga taatcgtatc gaaaaaaaat taacgccaat
     6901 atcttttgta ctttccgata atctcttgat tacttgtatc gatagaaaaa ccgaatttgt
     6961 ggatcggctg ctgacaaagc atggaaatca tttaaactcg tttgaaaaga tcatcacgta
     7021 tacattatta gatatttaca cccattacgt gaaagaacta agagagatga aaaagcgaat
     7081 tgacgctttg gataaagcag ctcgtaaaac aacggaaaat gaagaactgt ataaacaggc
     7141 agatcttgaa agagacatcg tatatatcga tcatacctta agagatcaac gggaaacaat
     7201 ggatcaatta tggaattctg aaactttcat caaacgttta gacgatgaac agctactcta
     7261 tgatgtccat ttgagacagc gacaaacaga aaaaatgatc gagatctatc gagatttatt
     7321 agagagtatt ggtgatctat tcaacgggat gatggacaat aatctaaatc atatcatgaa
     7381 atatctagat tcagctgcat taatcatttc cgttccggcg ttgttcgcag ggatttgggg
     7441 aatgaataca ggaggattac cgggtaaaag ttctgctcta ggctttatac tcgtagtctt
     7501 tggctctttg atagcagcag tagttttagg ttaccattta taccggaaag attatacaaa
     7561 ttaaagaatc tatttaaaac aggtatcaaa caaagaaatt tgttttggca atacaattta
     7621 aaaactagga ggaatacagc aatgacagaa ccaaaattaa tcgacccgcg aaacttgtac
     7681 catacggaga aatttcctaa acaagatcag gatacaccag ctttacagca gaatatgatt
     7741 cctgttcctg attgtggaga agaatcctat gaaggcaata atcaactaga aaaccgccgt
     7801 gtactaatca ctggtggaga ttcagggatc ggtcgtgcag cagcgattgc atttgctaga
     7861 gaaggggcag atatcgctct tcaattcttc ccaggagaag aaaaagatgc agaggaagta
     7921 gcaaaatacg tgaaagttgc aggacgtaag attgtcttac taccttttga tcttcgtgac
     7981 gaacaagcac ctaaagaaat catagataaa gccgtgagtg aacttggcgg gctagatacg
     8041 atggtactaa acgcaggaca gcaaatttct tgtcagtcta ttgctgagtt accacttgag
     8101 caagtcaaag acacatttat gataaacatc atcgctatgt ttgctttagt gaaagaagct
     8161 gttccgcata tcccagcagg aggagcaatc gtaacaacaa cttctgttca agcattcaat
     8221 ccaagcgaac atttattaga ttacgcagca acaaaagctt caatcgctaa ctttacgatc
     8281 ggtttagcaa aacagcttgc acctaaagga atccgtgtaa atggtgtagc acctggtcca
     8341 atctggacac cattacaact agacgaagga caaccttctg attcgatccc tgaatttggt
     8401 cagcaaagtt tactagaacg tgcaggtcag ccaggagaat tagcaccagt ttatgttttc
     8461 ttagcatcga ataaagcaag ttatgttaca gcccaaattt acggagtaac tggtggagaa
     8521 gcgatcaact tataagaagt tgatcgtttc acccctatga ggaggtgcga aaatgaataa
     8581 aggtgtaaaa acgatcggag tgatcggaac attacttttg ctatctgtgc ttttgtttgc
     8641 gatactatta agtgcaacct atccattgcc ttttcagcta gagaagtttc gattcttttc
     8701 catcactaat tcatacgtgc aacaatatgt attttggctt gccgttgcat ttgctatttt
     8761 gacaattatc acgttacttg ttttcctgtt ttatccaaaa acaatcggaa actttctact
     8821 gaaacatggt gatggggagt tgacgttgga taaaaaagca attgaaggaa tggttcgttc
     8881 tcacttgcat gaagatgaat tcatccattc accaaaagta aatgtcaaag caacgaaaaa
     8941 caagatcgcc gtcaatgtaa aaggggagtt gaaacgaact tcagcactca ttggtaaaac
     9001 aggaacattg atgaaagaaa tcgaaaatga agtacaacac atattgggaa caaaagagcc
     9061 agtgaaagta tcggtgaaat acacaggctt tgaagaacca gctaaacgaa gcaatgaccg
     9121 caaacgagta gaataggggg ggaccaaaaa tgaaagaact attttcgaca tacaagctcc
     9181 ctatcatctt tggggtactt ggattgatat tagccgtttt atggatcacc gtgggctttt
     9241 tcaagacctt attgatcttg atcatggcag cgatcggcgt cgctatcggt ttttatctga
     9301 aacaaacgaa aatcttagat cactatttta aatcttagga ggaaacatcc atgaataaca
     9361 ataacaaaaa taataacaat aaaatgaaca accaaaaacc agtgtctgca catccagacc
     9421 caacgacacc aaaccaatca aatggtgtga acgatgaaaa gaacaaaaca gcaccagtat
     9481 ctgcacatcc agatccagta gtccctaacg ttcaacaagg agtagaagag aagaaacatg
     9541 atgcagaaaa gcatgcacct catcatccag gaactccaga atctaaagtt ccagaacaac
     9601 atgatgcaat cgatccttct aaacctgtgg aagagcaaaa acatccttct gaccatgcga
     9661 aagcacaaga aaaacttagt tctgaccaca caaacggaca aggaaaactt ggttctgatc
     9721 atacaaataa ccaaggaaag catgattctg aacaggaaga ttcaatgcgc ggtgagctga
     9781 attatgaaga taaagttgtg caaaaaatca tcggaatcgc aattgaacaa gtagacggtt
     9841 tattatctgc aaacggtggt ttcttctcta atgtggcagg aaaacttgtg aatacagata
     9901 atgtaacggc tgggatcgaa acagaagtcg gtaaaaaaca agtagcagtt gatatggatg
     9961 tcattgtgga atatggcaaa gatatcgaaa aaatctttga agaaatgcaa gaagtaatcg
    10021 gcaaagaagt aaaaaatatg acacatttag aagtgatcga agtcaacgct aacgtagtgg
    10081 acatcaaaac aaaagaagaa tttgaaaaag atcaagaaac ggtgcaagac aaagtaactg
    10141 acgcagcgaa aaaaaccggt gaatttgctt cgaatcaaac agataaagta aaatcagcag
    10201 ctggaagcgg cgcacaaaaa gtaaaagaaa atacagaacc acgggttcag taataaggaa
    10261 gtaaaacatt aggaggaacg aaacatggga tttatttggt cacttatcgt cggaggaatt
    10321 atcggagcaa ttgcaggagc aatcacgaat aaaggttctt cgatggggat tattgcaaat
    10381 gtcgtagcag gtttagttgg atcagcactt ggtcaagcat tattaggttc ttggggacca
    10441 agtattgcag gaatggcaat cgtgccatca ttgattggtg ccatcatttt agtactaatc
    10501 gtatcattct ttgctcgaaa actgtaaaaa gacttttaaa aagaggtcgt gaaaaagctg
    10561 ttcttcatca agtaataaga acagccaaac aaaaatagct tctcatattt ttcatttggt
    10621 tgggcatatt atcgaagatg caagcttttg aacactgttt atacggaata agaggctgtg
    10681 acaagacttt tgtcacagcc tcttatttat gcgggcaaat tcccaattag atttttaaaa
    10741 gtttttcctt aaatgtgtct ttattgatac agagaagctt ctttaataaa acaatgcctc
    10801 cctaaatttt cttgagatag gaaaggtgaa catacaaaat aatacgacca ctttgaaaac
    10861 ccagatgatc cacaaatgga tcgtatgata ctgatgaagt aaaaagcaat ggatcagaaa
    10921 ctcaaagaga ttgaaaaaga caaggaagaa ataatatctc ttttttactc ttgtctgttt
    10981 tagccaataa tagctcgtaa agtaatctag acaaacaaat agaagtaaac aaagtttcgt
    11041 aagagcagca atcgtatcat gttgctctgc tagacgattg acgagcagga aaaatgttgg
    11101 taatggaata tagatcacga gtaatgaaag aaaaaagtaa acaataaatg gcatactatt
    11161 cctcctaatt gtgtgagttc gccctcattt taaaataacg atatttgttt gtgaagcttt
    11221 ttcgtgtcgt aacaaatgtt atctaatgta tttttaaata aataatcatt attatcaaaa
    11281 taat
//
LOCUS       DAJSMK010000075        11253 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.078, whole genome shotgun sequence.
ACCESSION   DAJSMK010000075 DAJSMK010000000
VERSION     DAJSMK010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11253
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.078"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ON488_002037"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="ON488_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HCR3232224.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ON488_002038"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="ON488_002038"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HCR3232225.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="ON488_002039"
     CDS             complement(2169..2906)
                     /locus_tag="ON488_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCR3232226.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="ON488_002040"
     CDS             complement(2997..3524)
                     /locus_tag="ON488_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232227.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="ON488_002041"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="ON488_002041"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HCR3232228.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="ON488_002042"
     CDS             complement(4401..4886)
                     /locus_tag="ON488_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HCR3232229.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="ON488_002043"
     CDS             complement(5039..5236)
                     /locus_tag="ON488_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232230.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ON488_002044"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="ON488_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HCR3232231.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ON488_002045"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="ON488_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HCR3232232.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="ON488_002046"
     CDS             9211..9423
                     /locus_tag="ON488_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HCR3232233.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="ON488_002047"
     CDS             9425..11104
                     /locus_tag="ON488_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCR3232234.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3588 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaa
//
LOCUS       DAJSMK010000076        11239 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.079, whole genome shotgun sequence.
ACCESSION   DAJSMK010000076 DAJSMK010000000
VERSION     DAJSMK010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.079"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            84..1130
                     /gene="gmd"
                     /locus_tag="ON488_002048"
     CDS             84..1130
                     /gene="gmd"
                     /locus_tag="ON488_002048"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HCR3232235.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
     gene            1210..2223
                     /locus_tag="ON488_002049"
     CDS             1210..2223
                     /locus_tag="ON488_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232236.1"
                     /translation="MATLCRCEAKITLVCGANHLDFAKRNLEQELPKELIDRVRYRPI
                     NTDIGLINREGTLLVDTGKLTEICEYFLAKVPSLAKTEAEWLKREAVSAVLCDMPIWA
                     MDACDMAGVPFLYVGNFTWTELYREFLPEHIWKEYAKRYGKIQHTMLYALNNEEMLEF
                     LQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVFVALGMSARFKQPIDVSHAPYDFIT
                     TLGVPLVGENVTVISNSTPNTQDYIAAADYVITKAGWGTVAECILAQRPMALFARDTV
                     LEDRTTICKLQKLGLAISVTPENLHRVERVIEDLKQLDTSNFDTFYDAASEIADKLIS
                     LMQ"
     gene            2260..3204
                     /locus_tag="ON488_002050"
     CDS             2260..3204
                     /locus_tag="ON488_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014424865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HCR3232237.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWKNGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            3272..4585
                     /locus_tag="ON488_002051"
     CDS             3272..4585
                     /locus_tag="ON488_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCR3232238.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVISASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIYADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            4669..5571
                     /locus_tag="ON488_002052"
     CDS             4669..5571
                     /locus_tag="ON488_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HCR3232239.1"
                     /translation="MMNLQKELRCLLLRKLGMLYAPGWTELCCVWSEYQGMTLTEVLQ
                     EHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPTDEYAIEKENGQLGKTEMWYVLD
                     ASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKKNDVFFIEAGTIHAIGAGALIAE
                     IQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVANLKGLSEPKQPLRVLKYRAGVAA
                     ELLCRCKHFEVSRMIVNTERRQTVHYRADSVSFRVLLCVNGCGTVRFDNESLDIYKGD
                     CLFVPADSTEISIHGSIQFLDVRG"
     gene            5576..7228
                     /locus_tag="ON488_002053"
     CDS             5576..7228
                     /locus_tag="ON488_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HCR3232240.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEKVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKADSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            7252..8118
                     /locus_tag="ON488_002054"
     CDS             7252..8118
                     /locus_tag="ON488_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232241.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(8160..8351)
                     /locus_tag="ON488_002055"
     CDS             complement(8160..8351)
                     /locus_tag="ON488_002055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232242.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCGKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            8381..8920
                     /locus_tag="ON488_002056"
     CDS             8381..8920
                     /locus_tag="ON488_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232243.1"
                     /translation="MQLLLYRIGDSTKIRFLINVRFRVIYSTVLPKGIPQRQKWMIHM
                     EEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSNLWFRQEISIAEIEDA
                     VLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGADVWKNISYLKVYTATPPKKP
                     TPPRFQSNGWSLFFSHKSA"
     gene            9048..9401
                     /locus_tag="ON488_002057"
     CDS             9048..9401
                     /locus_tag="ON488_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232244.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
     gene            9868..10344
                     /locus_tag="ON488_002058"
                     /pseudo
     CDS             9868..10344
                     /locus_tag="ON488_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290865.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            10344..10538
                     /locus_tag="ON488_002059"
     CDS             10344..10538
                     /locus_tag="ON488_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232245.1"
                     /translation="MAETRPKGYPKLKEYTPNRFMLSECHYDKARADRAVNFIGQLRH
                     TKGKWAGNRFWLLPWQEQII"
     gene            10544..10829
                     /locus_tag="ON488_002060"
                     /pseudo
     CDS             10544..10829
                     /locus_tag="ON488_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            10843..11209
                     /locus_tag="ON488_002061"
                     /pseudo
     CDS             10843..11209
                     /locus_tag="ON488_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
BASE COUNT         3154 a         2303 c         2854 g         2928 t
ORIGIN      
        1 attatcgtgt attcttgaaa agtattagaa attacgagcc atttatatgg tcttatcact
       61 tacataggaa aggataatgt atcatgaaaa aagcgctgat tactggtatt actggtcagg
      121 acggttccta tctggcagat ttcctgctag agaagggcta cgaagttcac ggtatcactc
      181 gccgtgcttc tatttccaat accgctcgca ttgaccattt gatgggcaag atcacccttc
      241 atgacggtga cctgtccgac tcatcttctc tgattcgtat catcagcatt gttcagcctg
      301 atgaaatcta taacctcgct gcacagagcc atgttcaggt ttcttttgat gttcctgagt
      361 actccggcga tgttgatgct ttgggcgtta tgcgtattct ggaagcttgc cgtattctgg
      421 gcctgacgaa gaagactaag atttatcagg catctacttc tgagctgtat ggcaaggttg
      481 aagaagttcc tcagcgtgaa accactccgt ttcatcctta cagcccttat gctgttgcaa
      541 agcagtatgg cttctggatc actaaggaat atcgtgaagc ttatggcatg ttcgctgtca
      601 acggtattct gttcaaccat gaatccgaac gtcgcggtga gaatttcgtc acccgtaaga
      661 tcaccctcgc tgccggccgc attgcagaag gcctgcagga ccatctggaa ctgggcaaca
      721 tggactccct gcgtgactgg ggctatgcaa aggactatgt tgagtgcatg tggatgattc
      781 tccagcatga gactcccgag gacttcgtga tcgctaccgg cgagcagcac actgttcgtg
      841 acttcaccga gaaggcattc gcagcaaatg gcatgaccat tcgttgggaa ggcactggca
      901 ttgatgaaaa gggctacgat gttgaaaccg gcaagatgct cgtttgtgta aatccacagt
      961 ggttccgtcc gactgacgtt gacaacctgt ggggcgaccc gactaaggca aagaccgttc
     1021 tcggttggaa tccgcagaag acctcttacg aggaactggt taacatcatg gcaaagcatg
     1081 accgtgaatt ggcaaagcgc gaagctgcaa tgaagaacgc agtcaagtaa gctgacattg
     1141 aataaacata tctgtttcta tctttccagt cacggcttcg gacatatcgc gcggaatctg
     1201 cccattatta tggcaacact ctgccgatgc gaagcgaaga ttacactggt ttgcggcgca
     1261 aatcatctgg attttgcaaa gcgcaatttg gagcaggaac tgcccaaaga gctgatagac
     1321 cgcgtgcgct atcgtccaat aaacacagat atcggtctga ttaaccgtga gggcacccta
     1381 ctggtggaca cgggtaagct gaccgagatc tgtgaatatt ttttggcaaa ggttccttct
     1441 ttggcaaaga cagaagccga atggctcaag cgagaagctg tcagcgcagt gctttgcgat
     1501 atgccaatct gggcaatgga tgcctgcgat atggcaggag tacctttcct gtatgtagga
     1561 aacttcactt ggacagagct gtatcgcgaa tttttacccg aacatatttg gaaagaatat
     1621 gccaagcgtt acggtaaaat tcagcacacc atgctttatg cgctaaataa cgaagaaatg
     1681 ttggaatttc tccaaaacag cgaaaaaaca ccgacttccg ttgtggcgcg tccgattcat
     1741 aacgacgaag tgcaacgcat taaatcacag catgaaaaac cgcctgtatt tgtcgcactc
     1801 ggtatgtccg cgcggttcaa acagccaatt gatgtcagtc acgcgccgta tgatttcatt
     1861 acaacgctag gtgttccgct tgtgggagaa aacgtaaccg ttatttctaa cagcaccccc
     1921 aatacacagg actatatagc ggcggcagat tacgttatta caaaggctgg atggggaact
     1981 gttgcggagt gtattctcgc acagcgtccg atggcactgt tcgcccgcga tacagttttg
     2041 gaagatagaa caactatttg taaattgcaa aaactgggtc tggcaatttc cgtcacaccg
     2101 gaaaacctcc accgcgtaga gcgggtgatt gaggacctca aacagctaga cacctcaaat
     2161 tttgatacat tttatgatgc tgcgagcgaa atcgcagaca aattgatttc tctcatgcaa
     2221 tgagagatgc tctaaattta gaaaggagca agcattatta tgatggaaaa agacgcaaaa
     2281 atctacgtag ccggtcatcg tggcatggct ggttccgcaa tcgtgcgcga gctgaaccgt
     2341 caggactaca acaatattat cacccgcacc cataaggagc ttgacctgtg ccgtcaggac
     2401 gctgttgaag catttttcgc acaggaaaag ccggattatg tatttctcgc tgctgcaaag
     2461 gttggcggta ttatcgcaaa ccagaacgct ctggcagact tcatgtatga aaacatgatt
     2521 ctggaaatga acgtcatcaa ctccgcatgg aagaatggct gtaagaagtt acagttcctc
     2581 ggttcttcct gtatctatcc gcgtatggca ccgcagccga tgccggaaag ctgtctgctg
     2641 acaagtgagc tggaaaagac caacgaggct tatgcactgg caaagatttc tggcctgaag
     2701 tactgtgagt ttctaaacaa gcagtacggt actgactata tctctgttat gcctactaac
     2761 ctgtatggac ctaacgacaa ctatcatcct actcacagtc atgtgctccc cgctttgatt
     2821 cgtcgcttcc atgaggctaa ggaagcaggt ctgcctactg ttacctgctg gggtgatggt
     2881 tctcctctgc gcgaattcct atatgttgac gatctggcaa acctgtgtgt gttcctgatg
     2941 aataactata gcggtgacga gactgttaat gcaggtactg gcaaggaact gtctatcaag
     3001 gaactgaccg agatggtagc aaaggttatt ggttacgaag gcgagattct gtgggatacc
     3061 agcaagccga acggtacacc tcgtaagctg ctggatgttt ccaaggcaac caagctggga
     3121 tggacatata agactgagtt ggaagatggc atccgtctgt cctacgagga cttcctgaat
     3181 aacccgatgc gtgctgaacg ctaatttacc gaggttgctg tgatttttga ggattgcagc
     3241 agcctctttc ttataaaaag gagagatcat tatgaatatt gttttactgt ctggcggttc
     3301 tggtaagcgc ctttggccgc tgtctaatga catccgttcc aagcagttca ttaagatttt
     3361 caaaactgaa gatggatatg aatccatggt tcagcgtgtc taccgccaga ttaagaaggt
     3421 agataacgac gcaactgtta cgattgcaac ctctaagaca caggtttctg ctatccataa
     3481 ccaacttggt gaggatgtgg gtgtatctgt agagccttgt cgccgcgata ccttcccggc
     3541 aatcgcattg gctaccgctt atctggtaga tgtgatgggc attgatccag aagagtccgt
     3601 agttgtttgc ccggttgacc cttacgtaga agatgactat tttgaggccc tgaaatctct
     3661 gtccgatcag gctgacaaag gcgaagctaa tctggtgctc atgggtattg aaccgactta
     3721 tccttccgag aagtacggct acatcattcc tgagagcgca gagcagactg ctttcgtaaa
     3781 taccttcaag gaaaaacctt ctgaggctgt ggcaaaggaa tatatcgcac agggtgcact
     3841 gtggaacggt ggtgtgtttg tctacaagct gaagtatgtc atggagcgtg cacatcagct
     3901 gattgacttt gtagattatc aggatctgtt caacaaatac gatactctga ctaagatttc
     3961 cttcgactat gccgttgttg agcatgagga caagattcag gtacagcgtt ttgctggtat
     4021 gtggaaggat ctggggactt ggaatactct gaccgaaggt atggaggaat ccattatcgg
     4081 taaaggtgtt atgaatgaga attgcgatgg cgtacacatc ctgaacgaac tggatgttcc
     4141 tgtgttggct atgggtctgc atgatgtggt catctctgca tctcgggaag gtattctggt
     4201 ttccgataag gaacagtcca gctatattaa gcctttcgtt gacaagttcg agcagcagat
     4261 catgttcgca gagaagtctt ggggtagtta taaggttatg gatgtagaag cagagagcat
     4321 gaccattaag gttactctga atgctagtca ctccatgaat tatcacagcc acaagaaccg
     4381 tgacgaggtg tgggtggttc tggccggtac tggtaagacc atcgtggatg gatatgagca
     4441 ggttgttaag gctggcgatg tgatcaccat gagtgctggc tgtcggcata ccatttatgc
     4501 agatactgag ctgaagctga ttgaagtaca gcttggcaag gatatcaatg ttaaagataa
     4561 acagaaattt gagttagagt attaaaaaac ggaggagggc tcgttataca gaaaccgttt
     4621 ttattgaagc cttccgcaaa ggattatctg tgggggggaa ccgcctgaat gatgaatttg
     4681 caaaaggaat tgagatgtct cctcttgcgg aaacttggaa tgctctacgc acccggatgg
     4741 accgagcttt gttgtgtctg gtcagagtat caggggatga ccttgacgga ggtgttgcaa
     4801 gaacacccag agtttctggg aacgcatccg cagaccaaag gagaattgcc gatcctgatc
     4861 aaattcattg atgcgaaaaa ggatttgtct gttcaggtac atcccacaga tgaatatgca
     4921 attgaaaaag aaaacgggca gcttggaaag acagagatgt ggtatgtact ggatgccagc
     4981 ttaatctatg ggctgcagaa aataacagaa gaagctgtga tccgtgaagc gattgctcag
     5041 ggaactgttg agcgttatct tcagaaggtt ccggtcaaaa agaatgatgt gttctttatt
     5101 gaggcgggaa cgattcatgc gattggtgcg ggtgcactaa ttgcagaaat tcaggaaaat
     5161 tccaatctga cttatcgtct ctacgattat gaccgtgttg acaaaaatgg taaaaagaga
     5221 gaacttcatg tagacaaagc gctagaagta gcgaacttga aagggttgtc agaaccgaaa
     5281 cagccgcttc gtgttctaaa atatcgtgct ggtgtagctg cggaattgct ttgcagatgc
     5341 aagcatttcg aggtctctcg tatgattgtc aacactgaga gaagacagac ggtacactat
     5401 cgtgcggatt cagtcagctt ccgtgtgttg ctgtgtgtca atggctgtgg taccgttcga
     5461 tttgataatg aatcgttgga catctataag ggggactgcc tttttgtgcc ggccgattct
     5521 actgaaatca gcattcacgg gtcgattcag tttctggatg tgagaggata ataatatgaa
     5581 ttataaagta gaatatgagc gttggctgaa tcatgccaat gcagatatta tagaagaact
     5641 gcgttcctat tctgagaagg acattgagga ctctttctat aaaaatttgt ctttcggtac
     5701 tggtggtctg cgtggtacca tcggtgcagg cactaatcgc atgaacgtac acaccgtagg
     5761 taaggcaagc caaggtctgg cagactatct gaataagaac tatgaagccg cttccgtggt
     5821 ggttggctat gattcccgta tcaaatctga tgtgtttgca aagactgccg cagacatctt
     5881 tgctgcaaat ggtattcagg tgcacttgtg gccagaactg cttcctgttc ctacagtatc
     5941 ttttgcgact cgttatctga aggcagatgc cggtgttatg attacggcat ctcataaccc
     6001 ttctaaatat aacggctaca aggtatacgg tgcagacggc tgtcagatta ctaccgaggc
     6061 tgctactgca attctggcag aaatcgaaaa gctggacatc tttgctgatg taaagatgga
     6121 tggcgatgct tctaagattg catccattca gtcggaagtt ctgactgctt tcatcgaaga
     6181 agtgaagggg cagtccgtcc tgtttggcga aaaagtggac aagaatgttg ctatcgtgta
     6241 ttctcctctg aatggtaccg gtctggtgcc tgttacccgc accctggcag agatgggata
     6301 cagcaatgtg accgttgtgg aagaacagcg tctgccggac ggtaatttcc cgacttgtcc
     6361 ttatccgaac cctgaaatta aggaagctat gtctctgggt atggagtatg ccaagaagta
     6421 caatgcggat ctgctgttgg ccactgaccc tgactgcgac cgtgttggta tcgcagttaa
     6481 gagcgcacat ggtgactatg ttctgttgtc tggtaatgag actggtctgc tacttctgga
     6541 ctacatctgt tctcagagaa ttaagcatgg aaaaatgcct gctgaccctg tgatggtcaa
     6601 gaccatcgtc accatggatt tgggtgaacg tatcgcatcc aactatggtg ttcgtaccat
     6661 cgatgtgctg accggcttta agtttatcgg tgagcagatt ggtatgttgg aaaaggctgg
     6721 taaggctgac agctatatct tcggctttga ggaatcttac ggctatctgt ccggtagcta
     6781 tgtccgtgac aaggacggtg ttaacgctgc ttatctaatc tgtgaaatgt tctcttacta
     6841 caagactcag ggtatcagcc tgctggataa gctgaatgag atttatacaa agtatggcta
     6901 ttgtttgaac accctgcatt ccttcgagtt tgacggtgcg gcaggtttta ccaagatgca
     6961 ggaaattatg gttgaattcc acaagggtct cgatataatt ggtggtaaga aggttattga
     7021 aactttagac tacagtaagg gcctgaatgg tctgccgaag tctgatgttt tgaagtttat
     7081 gctggaagat aactgctctg ttgtggttcg tccttctggt actgagccga agctgaagac
     7141 ctatatcagc gtcagcgcag agaacaagga agccgccgaa gctatggaag ctattatggc
     7201 tgctgaactg gcggaaatgt tcgagtaaga aaagaaagga gaaatcttgt aatggaggaa
     7261 ctgttttcta acgctttgaa atcggtgaag tcaaatcgtg tgctgtacac ggcatcgttc
     7321 tttgcaagat cctctctttt gtatttgcag gaaattggac agctgactgc tctgaaggca
     7381 catacatcta ggcgtacagg attgtcatct tacctttgtt tcctggtaga agttggttca
     7441 ggcacattgg agtataaggg gcagaaatat acgcttcaag taggagatat ggtgtttatt
     7501 gactgtttga agccgtatgt ccatgagtca tcagaagatg atttgtggac tttgcggtgg
     7561 tgccatttta atggcattgg tatgacggaa gtctacaaaa aataccttga acgaggtggt
     7621 caaccggtct ttaaaacatc aaaaacagat aagtatgctg acttgctgag gagccttcat
     7681 atggtggcag agggacagga gtatgtccgg gatatgaaaa tcaatgttct actcagtgaa
     7741 ctgctgatgc atttgatgga agattcttgg aatcctgaca aagtgccgaa tttctctaca
     7801 aaaaaaatgg aattgcagaa cataaaacaa tatctggatg accattacac ggagaagatt
     7861 acgctggatc agttgagtgc agagtttttt atcaataaac agtacttagc taagattttt
     7921 cgtgaaactt acggtacaac tgttgtcggt tatctgaatc agaaacgaat cacacaggcc
     7981 aagcacttgc tacgctttac aaatctaagt atggaagaga ttgcaacaaa aattggcata
     8041 acagatgcaa actatttttc cagaactttt ttcaaggtgg aaggtgttcg tcccagcgaa
     8101 ttccgcaaga tgtggtaata aaaagccggc ggtgttgagc cgccggtcag tacctgtcgt
     8161 taacccgcat tcaaagcttt aatctcagct ttgatttcag cacgaacacg atagtaatct
     8221 tcagtttcga tttcggtatc cagccgagtt gctgtctttc cgcagtcagg acaacgctct
     8281 ggctgttcgt cggcagggaa gctgtagtgg caggaatcac aggtgtaaat gtgatcgtca
     8341 cgtataatca tcacctacca atccagtgct tagatttttc atgcaattac tattatatcg
     8401 aattggtgat tccacaaaaa tccgcttctt gataaatgta cgattcagag tgatatatag
     8461 tactgtactg ccaaagggaa taccacaacg gcagaaatgg atgattcaca tggaagaaat
     8521 tatgcagatg attttaggga acgcaaaatt ccagctcgga caggtggttt cgacccctgc
     8581 tgtattggaa actttcaacc ccctgcagac cgcaaacggc attcccgaag ccttgagcaa
     8641 cctttggttt agacaggaaa ttagtattgc ggagatcgag gacgcagttc tggatgccaa
     8701 gaacggcaag gagctagcaa acagcctcaa ccgcatcaag cttttccgca agttcaccct
     8761 cgaccgagag ctggacggca tggtcagact gaagggcgcg gacgtctgga agaacatcag
     8821 ctacctcaag gtctacaccg ccacgccgcc taagaaaccg acccccccaa ggttccagtc
     8881 gaacggctgg agccttttct tctctcataa atcggcataa tgtatacaaa tacagctcca
     8941 aatgattgtg tagtatatgc ctgtggattg acttgatata gtcgagagac tatggcaata
     9001 tacacacaac caaaggggaa aatcccaaaa acaaggagga aacgctaatg gcaatgagcg
     9061 aaaaggcaaa gaaatatttg aaggagatca agggtgcaaa gaccatcccg gagctgaagg
     9121 atgtggagat cgcaatcaag cgagacggta tccttgcttg ggcagagttc accaagttga
     9181 acgaggcggt ggaagagaag aaggtcgccc ttcgcaagaa aaagcaggag accagccttc
     9241 aggagatcct tttctgggcc tacaaaaagg aatcagacaa gctgctgaag atgatggacg
     9301 agggagcaga caaggatgcc atccagatgc aggtccagcg ttacgacagc atcggccaga
     9361 tcattgcaga ggcagacctc gaagatgagt atgaggtttg agaatacagc ctgaaccact
     9421 aagaaccaaa taccgaaagg gacttctgaa acagacagag gtccctttct tttgctcact
     9481 ttggcggtca attatgaacc aaaaaccagt cgaatgattg tgtacattat ggctttcaaa
     9541 cgacttgata ataatcactt ttagagtgat atatgtacta caaaaaacaa aagactggag
     9601 aaaacaacag atgagcgaat acagaatcat ttatatcagc gacgaggacg gcggcgaggt
     9661 ggaaggatgt ggctacacgg ctacgatggt tatgatgcgg tcagaaactt cttggaattt
     9721 gcctgcggca tcttgaaaat cctgcgggtg cgattcatca gaagagtgga ctgaaataca
     9781 agttagcaga tagagaagag agtcaggttt cgacttggct ctgttctctg tctactggca
     9841 gaaatacatt gaagggaggt gacgactgtg gcaaccagag gaagaaaatc aaccccgaca
     9901 gccatgaaga agctggaggg aaatccgggc aatcgcccac tcaatgcaaa agagtcaacg
     9961 ccggaaaaga aggcaccgac ctgtccgaag tggctggaac cagaggcaaa gaaggaatgg
    10021 aagcgtctgg caaagcagat ggaggccatc ggaatcttga cagatgtgga tatggctgcc
    10081 tttgccggtt agtgccaagc ctacgcccgc tggaaggaag ccgaggaatt cattacccag
    10141 cacggtatca tcgtgaaaac cctatccggc tattggcagc aggtaccaca ggtgtttatt
    10201 gcccagacct atctgaaaat tatgaaccga ttttccgagc agttcggtct gacgccttcg
    10261 tccagaagcc gtatcattgc cggtgatggc ggtggtgtcg gagcagaaga tgcgatggag
    10321 gctctgttgg gaggtggtag ctgatggcag aaaccagacc aaagggctat cccaaattaa
    10381 aggaatacac accaaaccga ttcatgcttt cggaatgtca ctacgacaaa gccagagcgg
    10441 atcgggcggt gaactttatc ggacagctcc gacacaccaa aggcaaatgg gcaggcaacc
    10501 gcttctggct cttgccttgg caggaacaga tcatctagtg taatctcgct taactgtatt
    10561 aacggacgta gcgactttat taagagtgtt catggtagga gcattagttg caacaatgat
    10621 tgatattaaa tttttatggt accaacgatt ggcgatgtga cattgaatat gcaaaactat
    10681 atcgatatga tattatctaa aatcttactc gctgggatcg tcgaggtgtt tattggttgt
    10741 taggaaagaa aaatatgacc caactcgagc gatttttatc gtattacttg tgtgtggctt
    10801 tatctgcatt gtgtgtgatt tcgaaataag ggagagccaa aaatgagtag aaaattgata
    10861 ttgattagtc acggaaaatt ttgtgaggaa ttgaaaaaaa gtacaaaaat gattatggga
    10921 cctcaagaga atatctacac gttaccttta ttaccagaag atggcactga aacatacaga
    10981 caaaagctct tactgtcata gattcgttaa atgattttgt ggtactatgc gatcttttag
    11041 gcggtacacc tactaatatc atttctaaac tgataatgga aggacaacag attaaacttt
    11101 atgtcggatt aatcttccta tggtcattga atttatcaac tcgcaagtga ttggttcaga
    11161 gcccgagttt gttcgtgcag gatgtgaaag cattgtatct gtcaactaat taattagtgg
    11221 aatagtagaa gatgaagag
//
LOCUS       DAJSMK010000077        11203 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.080, whole genome shotgun sequence.
ACCESSION   DAJSMK010000077 DAJSMK010000000
VERSION     DAJSMK010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.080"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            6..305
                     /locus_tag="ON488_002062"
     CDS             6..305
                     /locus_tag="ON488_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3232246.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="ON488_002063"
     CDS             378..1739
                     /locus_tag="ON488_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HCR3232247.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="ON488_002064"
     CDS             1761..2021
                     /locus_tag="ON488_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232248.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="ON488_002065"
     CDS             2035..2787
                     /locus_tag="ON488_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HCR3232249.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="ON488_002066"
     CDS             complement(2881..3486)
                     /locus_tag="ON488_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HCR3232250.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="ON488_002067"
     CDS             complement(3539..4513)
                     /locus_tag="ON488_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HCR3232251.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="ON488_002068"
     CDS             complement(4891..5610)
                     /locus_tag="ON488_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3232252.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ON488_002069"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="ON488_002069"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HCR3232253.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="ON488_002070"
     CDS             7161..8558
                     /locus_tag="ON488_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCR3232254.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="ON488_002071"
     CDS             8639..9079
                     /locus_tag="ON488_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HCR3232255.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="ON488_002072"
     CDS             9227..9553
                     /locus_tag="ON488_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCR3232256.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="ON488_002073"
     CDS             9554..10303
                     /locus_tag="ON488_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232257.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="ON488_002074"
     CDS             complement(10383..10838)
                     /locus_tag="ON488_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HCR3232258.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
BASE COUNT         3553 a         1960 c         2299 g         3391 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tat
//
LOCUS       DAJSMK010000078        11199 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.081, whole genome shotgun sequence.
ACCESSION   DAJSMK010000078 DAJSMK010000000
VERSION     DAJSMK010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11199
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.081"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            161..1420
                     /gene="lysA"
                     /locus_tag="ON488_002075"
     CDS             161..1420
                     /gene="lysA"
                     /locus_tag="ON488_002075"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HCR3232259.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            1407..2207
                     /gene="dapF"
                     /locus_tag="ON488_002076"
     CDS             1407..2207
                     /gene="dapF"
                     /locus_tag="ON488_002076"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HCR3232260.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            2210..3091
                     /locus_tag="ON488_002077"
     CDS             2210..3091
                     /locus_tag="ON488_002077"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HCR3232261.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            3088..3804
                     /locus_tag="ON488_002078"
     CDS             3088..3804
                     /locus_tag="ON488_002078"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HCR3232262.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            3810..4505
                     /gene="dapD"
                     /locus_tag="ON488_002079"
     CDS             3810..4505
                     /gene="dapD"
                     /locus_tag="ON488_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HCR3232263.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            4521..5522
                     /locus_tag="ON488_002080"
     CDS             4521..5522
                     /locus_tag="ON488_002080"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HCR3232264.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            5519..6880
                     /locus_tag="ON488_002081"
     CDS             5519..6880
                     /locus_tag="ON488_002081"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HCR3232265.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            6840..7991
                     /locus_tag="ON488_002082"
     CDS             6840..7991
                     /locus_tag="ON488_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HCR3232266.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            7966..9135
                     /locus_tag="ON488_002083"
     CDS             7966..9135
                     /locus_tag="ON488_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCR3232267.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            9310..10689
                     /locus_tag="ON488_002084"
     CDS             9310..10689
                     /locus_tag="ON488_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCR3232268.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            10970..11199
                     /locus_tag="ON488_002085"
                     /pseudo
     CDS             10970..11199
                     /locus_tag="ON488_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3731 a         1952 c         2497 g         3019 t
ORIGIN      
        1 ttgtttttat aaccattttt attcttattt ttaaaaaaat atttcgaaat atactagaca
       61 attcagaaaa ttttgtttaa tattattcca ataaaattca aatctttatc aaatgaaatt
      121 ccaataaaaa cggaaaaaaa gtgaaaagag gaatgaaaaa atgacagaat tgataattgg
      181 cggagtcaca gcaagcacat tggcagaaaa gtataagaca cctctgtatg tgtatgatga
      241 agaaaagatg agacaaacga tgctgtcatt caagcgaggc tttgtatcga aacgttttga
      301 tacaaaagtg ctttacgcct ctaaagcatt ccaaacgatt gagatgctgc atttagttcg
      361 tgaatatgga ttcgggctag atgttgtcag tggtggggaa atctataccg ctttgcaagc
      421 tgattttcct agagatacta tctacttcca tggtaacaac aagacgccag aggaactgat
      481 ctatgcactt gaaaatgatt tgttgcatat tgttgccgat aatttgatgg aagttgaatt
      541 attagcagaa ttaagccaac gctatttaaa aaaaatctgt atcatgcttc ggttgaatgt
      601 cggagtagaa gcacatactc atgaatatat cgtcactgcg catattgatt caaaattcgg
      661 catgagctat gaaagtaaag agtgccaaca agcccttcag ttgataaaag aaagcagcta
      721 tctagagtta gaaggatttc atgctcatat cgggtcacaa atttttgatg ttactgcttg
      781 gttagctgaa atcgacaaat tgacgaatta cttaaccgat tttgaccaac ctctttcctt
      841 gaatcttggc ggagggtttg ggattcgtta tacacaaaat gatcagccga tcccagtcga
      901 agaggcacta aaaaaactga ttgaatatac ggaagaagct ttggaaaaac gaaaactgac
      961 cattcgtcaa ttactgatcg aaccgggtag aagtattgtt ggagaagctg gtacaacact
     1021 atacacgatt ggtttcatca aaaagacacc acataaaaaa tattactttg tagatggcgg
     1081 gatgacagat aatatccgtc cagctctgta tcaggcagaa tacgattgtg atttagcagc
     1141 aaaactgtcg gaagaaaaaa cagagaaagt gacgattgca ggaaaaatgt gtgaatcagg
     1201 cgatgtggta attaaagaag cttatttgcc gaaagcagaa tcgggtgatc ttttagctgt
     1261 ttattccacg ggagcttatg gatactcgat gagcagcaac tacaatcgag cgacacgacc
     1321 agcagttgtt tttgtcaata atggccaatc aagactgatt gttcgcagac aagcattttc
     1381 tgatctacta aggggggaag tttcctatga tccttcataa atataatggc tgcggaaatg
     1441 attttatctt attagattac gcagaagaca cagattatag tcaattagcc gcttctttat
     1501 gcacaaaaga aaaatatgat atagacggat tgatcgccgt aaaaatcgat ccgttggaaa
     1561 tgatctatta caacaaagat ggcagccgcg cgccgatgtg cggaaatggc attcgctgtt
     1621 ttgctcgata cgtaaatgat cagaacatga tgaatgaaca ggaattcaac gtagagacat
     1681 tagcaggcac aagaaaaatt acggtgttgg atccctcacc tttttattgc agcgtagata
     1741 tgggagtgcc agatgattct ccggaaaaaa tcaaagctaa tcaaacttat ccaataaaaa
     1801 accaggaaat agagatcaat ggtgaaaaag taacgatcac tagtttattt ttaggaacga
     1861 ttcataccgt tgtttttgtt gaaaatgcgc gtgaggaagt ctggagaaaa agaggtgaac
     1921 tgatctgtca tcatcctttg ttcaaagaaa aaaccaatgt caactttgta gaagtagtca
     1981 atgaacaaga attgatcgtc cgtacctatg aaagaggagt aggttggaca cttgcttgcg
     2041 gtacaggttg ctgtgcctct tatgtggttg ctaaggaaac tgggaaaatt tcagcagatc
     2101 aggtagttgt tcacttggaa caaggagact tgatgatctc tggtgaggat gcgatacaaa
     2161 tggctggccc agcagttcat gaatggacaa gaatattgga ggaatgaaga tgataaaagg
     2221 ttcgatcgtg gcgctgatca cgccgatgaa tgaagaggga tcagtagatt atgctggttt
     2281 ggaaaaattg atccaattcc atttagatga acaaacagat ggattattag ttttaggtac
     2341 aacaggagaa tcttctacgc tcacacaatc tgaggaggag cagatccttc aactgacagt
     2401 aaagaaagtg gctggccgtg tgccggtgat tgcaggagct ggaacgaata atacgaaaga
     2461 aacgattgaa aaagcgaagc attttgcttc tttgggggca gacgcacttt tggtcatcac
     2521 cccttactac aacaaaacaa gtgatgcagg actagctgct cattttacag caattgcaga
     2581 agcctcaccg attccgctta ttttgtataa tgttccttct agaacaggca tgtcgattcc
     2641 aatccatgta ttagtaaatt tagcagaaca tcctaatatc attggtttga aagaagcctc
     2701 aggagatatg gcttatgtga tggatgccgc tcggttgatt ggagaagaat tcttccttta
     2761 cagtggaaat gatgatttga tcctaccagt aatgagtgta ggaggaagcg gtgtaataag
     2821 tgtatgggcg aatatccaac ctaaaatagt ccatgaatta gtaaaagata cgcaggacgg
     2881 aagatggcag caagcaaaag aaaagcaatt aaatgcactt gaactgatcc atgccttgtt
     2941 cagtgagacc aatcctattc ctgtcaaagc agccatgtca ttattagact taccttccgg
     3001 acctctacgc ctgcctttag tttctctttc aaaagagaaa aagaaacaat tagctcagct
     3061 tttgttaaaa gaaaggacgg ttgaaaaatg aaaatcggac tgattggcag tggacagatg
     3121 ggaaatagag tcgaagaagt tgcacaagaa agaggagata cggtccttct tttacggacg
     3181 gcacctaaag aagcaactac gcttgctttt acggaactgc cagaactgct tattgatttt
     3241 tctcatccag ataatttaga gaaaatcctt tcgtatagct tatcatatca acttccgtta
     3301 gtcattggca cgacaggtta tacacaatca cagttccaag aaataaaaga acatgccaaa
     3361 catgtacctg tgatgtatag tgctaatttt tcgttcggca tcatggtgat gaatcaacta
     3421 atcaagcaag cagctgcaat gttgcaaggc tggcagatcg aactgattga aaaacatcat
     3481 agtcgtaaaa aagatgcacc atctggtact gcaaatatgc tgcttcaaac aatccaagaa
     3541 gtgcaaaagc tgcagcccgt atacaactgg caagggaaaa aaagagaaga aaaccaaatt
     3601 ggtgtacaca gtattcgtgc aggttcttta cctggtgaac atgatgtatt gtttgctgct
     3661 actgatgaaa tatttacgat caaacatgaa tctttttcta atcgaatctt tgctgcaggc
     3721 gcagtagaag cagcggactg gttgaaagat cagtcaccag gttattacaa attagaagat
     3781 ttattaatgg acaaaggggt gtaaaaaacg tggaagctca agaaatcatc cgctacattc
     3841 aaacggcatc taaaaagacg cctgtgaaag tctatctgaa tgtaaccgag ccaatcgaat
     3901 ttaaagaaag taaagttttt ggtgaaggaa gcagcttcgt tgtttttggt gactatgaga
     3961 cgattgctcc ggttttagaa gctgaatcag aaaaaatcat tgaaatcgaa atcgaaactg
     4021 ctgcaagata cagcgcagtt cctttgctag atattaaaaa aattaatgct cgtatcgaac
     4081 caggtgctat tatcagagat caagtgtcaa tcggcaacaa tgccgtgatc atgatgggag
     4141 cgattatcaa tattggtgca gtaatcggtg aaaacacgat gattgatatg ggtgctgtct
     4201 taggtggacg agcgacagtg ggcaaaaact gccatattgg tgcaggagct gtcttagcag
     4261 gtgtgatcga accagcatcg gccaaaccgg ttatcgtaga agacggcgta ctggtaggtg
     4321 cgaatgcagt gattgttgaa ggtgtccata tcggaaaaga tgcagtcgtg gcagcaggag
     4381 cagtggtttt agaagatgtg gcagcagaaa ctgttgtcgg tggaatacct gcacgtgtat
     4441 taaaaataag tgatgatcag acaaaagaaa atacagcatt gattgctgcg ttacgcgaat
     4501 tatagaggag atggagaaaa atgcgcgaaa tagatacctg tattgtgggg gcaaccggat
     4561 tagtcggcca aacgatgctc aaagtgttag aagaatatga ttttccagta ggacgattga
     4621 aattattagc ttcaaaacgt tcagccggta aagtttgtgt attcaagaaa aagaaacaca
     4681 ctgtacagga attgacagaa acttcatttg aaggatatga tttagcgcta ttttctgcag
     4741 gtgcttctgt atccaaagag tttgcgccaa tcgcacgaag tcagggacta tttgtcatag
     4801 ataattcctc agcatggcgg gaagattcgg atattccatt aatcgttcca gaggtcaatc
     4861 tggaagacta tacattgaat cggctgattg caaatccaaa ttgttcaacc attcaagcgg
     4921 tacttccgct taaagcttta caagaagcct ttggtatcca gcgagtcaat tattcgacct
     4981 atcaagcagt ttctggttcc gggcaaaaag gcattgaaga tcttcatcgt acgcaaaatg
     5041 acgaggaacc agttttgtat ccttataata ttagccaaac ggtgattccg gaaatcgatc
     5101 agcctttgga aaatgggtat acaaaagaag aacagaaaat gataaatgag acccgtaaga
     5161 ttctgcatca gcctgctttg ccagtatcag caacctgcgt acgtgtgcca atcgaaaatg
     5221 gacatggagt ctctgtggca gttcaactgc aaaaagagtt tacgacggaa gaaattagag
     5281 agtgtctcag ccagtttcca gggattcaat tagaagatga tctagcagca cataaatatc
     5341 cgacgagcat tcttgctaga ggaacagata tggtttatgt tgggaggatc agaaaagaca
     5401 cttctttaga gaacggattg ttgttctata cgactgccga taacatacgc aaaggagccg
     5461 ctgcgaatgc cgtacagatt gctgcagctt taatgcagaa aatagcggag gtggcaagat
     5521 gagtaatacg ctgaaagtag cgaaattcgg cggaacatcg atgtctcatg aagagcaatt
     5581 caaaaaagtc cgtacaattg ttctttcaga tcccaatcgc caagtgatcg ttgtttctgc
     5641 tttaggcaaa cgtacgtcag atgatgacaa agtaacagac ttactttatt tgatttatgc
     5701 ttaccttcag catcatgttg attggacacc cctttggaaa aggatttgtg atcgtttcat
     5761 tcaagtaaga gatgttcttg ccctgcagtt acctattgaa gatgaactag cacgcataca
     5821 gaaacaactg gaagacgaaa agataactga agattattta gtaagtagag gtgaatatct
     5881 gactgctcaa ctgatggctg agtatcttgg ttaccagttt attgacgcaa aagacctgat
     5941 tttctttgac tatgatggga aaatcgatca ggaaaaaaca gcacaggaaa tcacaaaagc
     6001 atttaaaaga tatccgaaaa tggttgttcc agggttttac ggggcgaacc ctgcaggaaa
     6061 agaaaaatta ttgggccgtg ggggaagcga cattaccggc gcgatactgg cgaagatgtt
     6121 gcaagcggaa agttatgaga attggacgga tgtttcagga atcatgatgg ctgatccgcg
     6181 aatcatcgat catcctaaaa tcatcgagga aatctctttt agagaactga gagagatggc
     6241 ttatatgggg gctaacgttc ttcatgaagc agctgttttc ccagttcaag aggctgatat
     6301 ccccatccaa ataaaaaata ccaatgatcc tttcgctcaa gggacaaaaa tatcaaatca
     6361 cgaaatagaa aaggaaaatg gactgacagg aatagctgga cgcaaggatt ttctttccat
     6421 cactttattc aaacgtcata tgtccgatga aatcgggttt atctggaaag caatgagcat
     6481 ttttgctaaa catgagatat caatcgaaca tattccttca gggatcgaca atatcggagt
     6541 gatcgtctca gcagaagcga ttgccgataa gttatttctc atcacgaaag aattaaaaga
     6601 aacacttggc gtggaagaaa tcgtcgtgat cgaagactta gctttgatct ctgtcgttgg
     6661 gggtccgcat aaagaattga ttggattatc tgggaaagtg ttatcgatat tgaacaaatt
     6721 agaaattcgc acatcgatct tatcacaagg agcacaggag ttgaatctga tcatcggtgt
     6781 accgaataat caatatgaaa cagtagtgaa gggtatctat gaagggatgg tgaatacgga
     6841 tgctgaaaga atatcgaatg gcactccatc aaattcctga aatcgggttt catgaattca
     6901 agacaaaaaa atatttatat gaacaagtaa aaaacagcga ggccgttatc catgaaatcg
     6961 gcgaaacagg actactcctt tattttgata atcagcaaga agaaacgatt gcttttcgaa
     7021 cagatatcga tgcactgcca gtcaaagaag aaacgaatct ctcttttgct tctaagcatg
     7081 aaggttatat gcatgcatgt ggtcatgacg gacatatggc gatgctttta gggttgactg
     7141 actttataac taaacacatt gaggatctta tttataatgt agtactgatc tatcagccat
     7201 cagaagaaat ttccggtggc gcacaaagcg ttattcagtc aggattgttg gataaatatg
     7261 aagtacaagc aatatttggc tttcatctat ggcctggact agctaaggga gaagttttct
     7321 ctcgaccagg acctttgatg gcacaaagca gtgaaacaga cattatcatt aaaggccagt
     7381 ctgcacatat tgcttctagt gaaaaaggaa tcgatagtct ggaggcagct gtacgatttt
     7441 tgaagaatgt ttatgatttt gaccggcaat taccggcaga gtggaatcat ctaatgaaat
     7501 ttggccaaat ccaaggtgga acgatccgaa atgttttagc tggagaagtt attgtatccg
     7561 gaagtatccg ttcttacagt tcagatatgc aaaattattt gaagagggga ttagaccatt
     7621 tagcagaaca gtttcactct acagctacta tttcttttcg ctataatgac ggctatccag
     7681 ctgtaatcaa ccatagaggc ttatatgcag cactgttaga ttcaaacaaa ctacatgaat
     7741 tagatgctcc agttcttcaa gccgaagatt ttggcatata tacgcaacaa tatccatgtg
     7801 tatttttctt tttaggtgtc ggtgataccc ctgctttaca tgatccgacg ttcgattttg
     7861 atatggatgt tttagaaaat ggtgtagaat ggtacaaaac gattcttttt acagaaaatc
     7921 ttcttgtaaa aatcgatagc agttcaaaag aggagcgagt aaataatgat gaatttatcc
     7981 aatcgattta gtcctaggct ttctagaata gaagtatcaa aaatacgaca attcgatcag
     8041 caaatatcgt cgataccaga tgtgatcaaa ctcaccctgg gagaaccgga ttttccaact
     8101 cctgaacatg tcaagcaagc aggaatagca gcgattgaag aagacttttc tcactatacc
     8161 ggaatgagag gattagagga actgcgggaa gcggcttgta tatttcagca acagcgttat
     8221 ggattaactt atgatccgca aacggaagtt ttgacgacag ttggtgcaac ggaagcgatt
     8281 gcctctgcgt tgttatctgt tttggaagaa ggagacaagg ttcttattcc agcgcctgct
     8341 tattcaggat atcagccatt agtggaacta gctggtgctg aattgatccc gatagatact
     8401 tctgacacag ggtttgtctg tcagccggaa caatttgaac gagcatttga acaatatgga
     8461 tcagctgtca aagcagtcat tttaaactat cctaacaatc ctactgggac gacattgtct
     8521 gcaaaacaat tgaaagcaat cgctgaggtt ttaaaaaaat atccggtatt tgttataagt
     8581 gatgaagtat atgctgaatt gacttatagt ggaacgcata tgtccatagc tacttatctt
     8641 ccagaacaaa caatcgtgat aagcgggtta tccaagtcac atgcgatgac tggttggcga
     8701 gtgggcttta tttttgctca aaaagccctt attgacgaac taattaaagt ccatcaatat
     8761 ctggtgactg ccgctacaac gatgtcgcaa aaagctgcgg ctgaagcgct aataaatggg
     8821 gtgaaagata gcgagaatat gaaagagcaa tatcaaacac gaagagacta tctggtccag
     8881 caattggcgc ctttaggatt tgaagtgacc cagccaaacg gtgcatttta cttgttttgc
     8941 aaactcccag ctgccattca aactgactct tggcagtttt gtgtagaatt agcggaacag
     9001 gcaaaagttg cgtgtatccc aggaattgca tttggcccag aaggagaagg ttatatccgg
     9061 atttcttatg ctagcagcat ggaaaaatta catgaggcct gcaaacggat caaagacttt
     9121 ttaacagaac agtgattcat agattttatc aaaaaaacaa tcgttaattt tgcggtatat
     9181 tctgcaagga gacgattgtt ttttaaattt agttcaaatg aacgcgtttc ttttgattca
     9241 taactaatgt aatgttaagt ttaaattgtt tagaatgatt ttaaaagaat attcaaggag
     9301 gtttcatcaa tggaaaaaat caaagttgtc attgtaggtg catctcatgg agggcatcaa
     9361 tcgatcttgg aactattgac acgatacggt gaaaatgtag atatcacgct atttgaagca
     9421 ggagactata tttccttcat gtcatgtggt atggagctgt atttagaaga caaggtaaca
     9481 gatgtaaatg atgtacgtaa tttcagacca gaaaactttc cgcaatccaa tgttcatatt
     9541 ttaaataatc acgaagtaaa aacgatcgat gccgataaaa aaacagtaac ggttactagc
     9601 gcatcagata acgaaacaaa agaatatcct tatgacaaat tgattttgag ttctggtgtc
     9661 aaaccaaaca atctgccagt accaggagca gatctagaaa atgtctactt gatgcgtgga
     9721 tacaattggg caaccaaaat caaagaaaaa ttaaatgatc cggctattaa aaaaatcgct
     9781 gtcgtaggtg cgggttacat tgggatcgaa gcagcagaag caagccgaaa agctgggaaa
     9841 gaagtcgtat tgcttgatgt gatcgataga cctttaggca cttatttaga tgctgagatg
     9901 acagatattt tagaacaaca cctaaatgaa aacggtattg aagttttgac aaatgcaaaa
     9961 atcgaagctt ttactggtaa cggaaaagtt gaggcaatca aaacaagtga aaaagaaatc
    10021 ccagcagatc tagtcattca agctgccggt gtgaaggcaa atacagaatg gttaaaaggg
    10081 atcgtcgact tagatgaacg tggctggatc caaacaaatg aatacttgca aacgaatctt
    10141 ccagatgtgt atgcagtagg agatgctaca cttgcttatt ctatcccagc acgcaaaaaa
    10201 atgccgatcg ctttagcgac tgttgcacgt agagaagcac gttatgtagt aaaacatctt
    10261 tttgaagaag taccaaacaa accgttcggc ggagtcgtag gttcctctgc attaagtgtc
    10321 tttgactatc attttgcagc aagcggattg aatagcttta cagcagcaaa agcaggagta
    10381 gatgtacgag tgtcttatta tgaagatacg ttacgaccaa aatatgtacc agaagaacaa
    10441 ggaaatccaa aagtgtccat ccaattattc tcggatccaa tgacccatca attgctagga
    10501 ggagcagtat tatctaccta tgatgttaca ggtcaaggaa atgtattggc actagcgatc
    10561 caaaacaaac tgactttaga agaactagca gaagctgact tcttcttcca gccaggcttt
    10621 gaccgacaat ggagcatgtt gaatctagcc gctcaacaag cgttaggaga agaaccattt
    10681 gtagaataag aaaacgaaat atttgaaaag aggttgtgaa aaagctgcct tgcatcaagt
    10741 aataagaaca gccaagtaaa aacagcttct tatgttttta acttggctgg acttattacc
    10801 gcagatgcaa gcttttgaac accgtttatt ttcaaaaaag ggactgtgac acgatttgtg
    10861 taccgacccc caaaagttag accaaaaaat ctaacttttg gaggtcggta ttttttatgg
    10921 ttaaatatac ttttgaactt aaattaaaga tcgttcatga ttatttggat ggcaaaggcg
    10981 attggaccgt aaaaatccag atcaagagat tgaagcggaa atgcttaaaa ttcgggagaa
    11041 gcacaaggat tatggctgtt tacggatgac caatgaacta agaaaccgcg gtttctctat
    11101 caataaaaag aaagttcagc gcttgatcaa gaagctagga ataaaagtaa cggcatacac
    11161 gcgtaaatca cgtcgctaca attcttatcg aggaaaagt
//
LOCUS       DAJSMK010000079        10812 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.082, whole genome shotgun sequence.
ACCESSION   DAJSMK010000079 DAJSMK010000000
VERSION     DAJSMK010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.082"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(122..1339)
                     /locus_tag="ON488_002086"
     CDS             complement(122..1339)
                     /locus_tag="ON488_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCR3232269.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQKKALATQMIKKAEGSPCFLLYQTFP
                     GIGALTAALLLGELGDITRFKTHKQLNAFVGIDIRRYHSGKYTGQDRINKRGNPKARK
                     IIFFTIRNMIRQQRAAPNHIVDYYYKLKKQPIPKKDKVATVACMNKLLKCMHAMVRAH
                     TEYDYAYAVSVDH"
     gene            complement(1605..2972)
                     /gene="nhaC"
                     /locus_tag="ON488_002087"
     CDS             complement(1605..2972)
                     /gene="nhaC"
                     /locus_tag="ON488_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HCR3232270.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(3081..4502)
                     /locus_tag="ON488_002088"
     CDS             complement(3081..4502)
                     /locus_tag="ON488_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3232271.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(4745..6622)
                     /gene="tdc"
                     /locus_tag="ON488_002089"
     CDS             complement(4745..6622)
                     /gene="tdc"
                     /locus_tag="ON488_002089"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HCR3232272.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(6913..8169)
                     /locus_tag="ON488_002090"
     CDS             complement(6913..8169)
                     /locus_tag="ON488_002090"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HCR3232273.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(8281..8486)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            8749..10050
                     /locus_tag="ON488_002091"
     CDS             8749..10050
                     /locus_tag="ON488_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HCR3232274.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(10119..10718)
                     /locus_tag="ON488_002092"
     CDS             complement(10119..10718)
                     /locus_tag="ON488_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3232275.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
BASE COUNT         3223 a         2207 c         1985 g         3397 t
ORIGIN      
        1 aaaaggtgca agaaaaatag ctcgtaaacg aaagcgacaa aatcaaagca caccaaataa
       61 agccccgttc gtaaaaaatt ttcgatctgg gcaaagaagt ggtatactgt aagtggttta
      121 gttaatggtc cactgagacc gcgtacgcat agtcgtactc tgtatgtgcc ctaaccatag
      181 cgtgcataca tttcagaagc ttgttcatac aagcaactgt ggcaacctta tctttcttag
      241 ggataggttg cttttttaat ttgtagtaat aatcgacaat atgattagga gctgcgcgtt
      301 gctggcgaat catatttcga atggtgaaga aaataatttt ccgtgctttg ggattaccac
      361 gcttattgat gcggtcttgg ccagtatact tacctgaatg ataccgtcgg atgtcgattc
      421 cgacaaaggc attcaattgt ttatgggttt taaatcgtgt gatatctcct aattcaccga
      481 gcaataaagc ggctgtgagt gcgccaatcc cagggaacgt ttggtacaac aaaaagcaag
      541 gagagccttc ggcttttttg atcatttgtg tcgccagtgc ttttttttgt tcgagtaaat
      601 cttggagaag ttcggcgtaa tagatcgttt tttgacagtg gatactgtct ttttcaacag
      661 ctggataggc acactgtgca tagtggatga tttgatctgc cttttgctcg gcacgattcg
      721 cggagatttt tttccgtgtt tcgttgatca gtttattttt tatttttgtc cgagtagatg
      781 ccaatacaaa atctggatgg ggaaaaagac ggatcaatgt caatgcgtaa ggggtcagcc
      841 tgtttgaaaa gaactgttca agctctggaa aagtcaattg aaggcagttg tgtaaatcca
      901 tgcgcagacg agtgattttc ttctcaattt cttgataaaa acgggctaaa tcgcgcatct
      961 ctaagtaaaa attgctttgt acttcttttg gctgacgttg atttttaaga tgagtctgtg
     1021 cgagccggtg ggcatccgat ttatctgttt tccaactgcg taaggtgctt tcttccatct
     1081 gttttttcgc ctctaacggg tttaacaaac agtaagaaaa gtgatgatct tgaaagaact
     1141 tttcgactgg tctggaataa atccccgttg cttcaaaaac aatcaatgga cgctcaggca
     1201 agtgctggat ctcttcgagt aatgcatgaa atcctctttg agtgtgttca atctcgtctt
     1261 caaataagca ggtgtcgtct ttgtatagga cactgtagct gtgtcccatt gaaacatcta
     1321 atgcaagaat gtaaggcatt tgttttcctc ctttttaagt tttgaaagaa ctttactgct
     1381 tcatttcgat tccaatttcc tatacacggg ctcatggccc caacatacgt aaacctgatt
     1441 ctaaaatgac agtaaagaag ttcggttttt gatagggact cgtagtcctc aaggctttgt
     1501 tcgaactttc tttcactctt cactataatc taaaaataga aaatagagga gaacatcatt
     1561 cgtcaatgat gttcccctct aatcttagta tgtttttcct tccttcaatt ttttacacgt
     1621 cgacgattca ataaaaaacc gcctaatatt gtaaagacag gtgcaagaat cgagaaaaag
     1681 gcgaatggca agtaatgcaa cgcgctaact ttcatcgttc ccataatgaa tgtgccgctg
     1741 actccccacg gtacgagaga attgacggtc gcacctgaat ccgctagtgt tcgtgtcaaa
     1801 taggtttttg ataagccaac gtcatcaaaa gaacgcttga atgtttctcc tggaagaatg
     1861 atggacagat actgttctcc aacgatcaga ttgattccga tacagctcaa ggcagtaaac
     1921 ccgactaaac gagaaggtcg gtccatcttt tcttttaatt cttgaacgat ggtatcaacg
     1981 atcagatatt tgatcagtaa cccacctaat gccaatgcaa gtaaaatcaa actagcagaa
     2041 cctaacatac tcatgatccc gcctcgagaa agcagttcat ctagctttgg atcaggtgta
     2101 tttgcgacat aaccattcat caagatgtct gctgcttttc cgaccgtcaa acttttctca
     2161 tggataaaag aaagaacgag agcagctgtc gatcccgcta gtaatgtagg gatagccgga
     2221 atttttttga ttgccccccc aaataaaata actagtggaa tcaatgtcca aggagagatc
     2281 caaaagctcg ctttcatgtt ttggatcatt tcattgatac tagctagatc ggctgaatga
     2341 ctgttatgtc ctaatatcgt ataaaaaatc aacgaaagga cgaatgctgg gaaatccgta
     2401 taacgcatac cagcgatatg ttcgaataga ttaactcctc caatacccgc tgccaagttg
     2461 gtcgtatctg ataaaggcga gcagttattc cctaaaaagg caccggaaac gactgcgcct
     2521 gtagtcattg catcattgaa tccaagtaaa tgaccgatcc ccaaaaaagc aattccaatc
     2581 gtcgaaatcg ttgtaaatga actgccgaca gtcactccga caattgcaca aacaagaaat
     2641 gctgtcggta aaaagaaacg cacagaaaca agtttaaatc cataaaccat aatcgtaggg
     2701 atggttccag ataaaatcca tgaagcaact aagacaccaa tcaaaagaaa aatcaggatt
     2761 ggaatgatcc ctggagtgat tcctttgatg atcccgtcat ggatctcatc ccatgtgaac
     2821 tttttaaatc tgccataaaa caacaaacac atgaaagctg caaggatcgg gatatgtggc
     2881 gagagctgga atccgatgat cagtactcct aggagtgcca acaacacgat caatacagcg
     2941 atactttctt ttaaagaaat atttttattc atcgtcgatc tcctatttca aatgaaaagg
     3001 ccctgccatg aaaaaactat tcacttggca ggacctccta ctaaatcagc gacaaaacgt
     3061 cggctgaaag acttattttt ttatttttct tctaaacttt tttctacctc aatcccccaa
     3121 gaatctttct tgaagtgatt gatgatcaat ggaataacga acatgaccac tgtgatagct
     3181 gctactaata atgcatcact caatgtcgct gtacctaatg tagcaaatac gacaacgatg
     3241 atagagaaga tcagcatgca gctgactacc caagctaatc cgtttccgtt tttaccaatt
     3301 cggtaaggac gttcgaattc tggatgtttc ttacgcattt taagcaatga aacagcaatc
     3361 aaaatgtaca cgatacaata aataacagtt gtagcatttg taagtgtcaa gaatacagca
     3421 cttacgtcat ccattacacc ataaagcaaa gcaaataatg aaataacgat tgattgtgtt
     3481 agaacgacat ttctagatac gccgtatttg ttttctttat ggaatccgaa ttttggtgga
     3541 aggaatcctt cacgagctac ttggatgatt gtttttgatg gtccagtaac ccaagctgat
     3601 aattgtaaaa gcacaccaat aaataccatg aagctgaaga tatttccgat cacttctggt
     3661 aagcctagga tttgacagtc aatcaagata ggctgcgtga tatttgctaa ttccattttt
     3721 ccatctggta cgacatttgc tacaagcatc gcattgatga cattcaataa aactaatccg
     3781 atcaaagcga taaatacgcc ttttgtataa ttttttgttg cgtctttcaa acgaggcatg
     3841 taaacagaac tcatttcgat cccaacaaaa ataaatgtga taccagctaa gtatttcaat
     3901 gaatcaatat gttccaagtc agggaaagct tttgaccatg aaaagtcacc tagatagccg
     3961 tttgagacta gtccgacttt gaaggctgcc aaaacaccta aaacgaacat gatgactact
     4021 gggatatata cccctagcca tacaccgatg ttcccgccga cttttgccat atcgaatttc
     4081 aagttcaaga tcgtgatgat ccagtagata actaaaatac aacctaaaac gaaccagtga
     4141 ttattgccaa gttctacatt accaaatgtg tttcctaaca atggtcctaa agtagaagcg
     4201 accattacca tacctgggaa catttgcacc cataatagcc atgcaacgac aaatccccat
     4261 ttgctgccca gtgctgtttt tacccataac tgaggaccgc cttcttgagg aagcatcgtg
     4321 gaaagctcac cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa
     4381 taaaaaatca atgtccaacc gactgcggct aacgtaggaa tactccgaac cgttgcacac
     4441 agtgccattg tcagaccgat aaaggtccca agacccattt tacttacttc agatttactc
     4501 accgttgaca ctctccttga ttttttggat aaaataacgg tgtctttgaa gtagtttcag
     4561 caataaacga aacaattcag cgaatatttg aggggattct ttgagtttat tgcttgaagg
     4621 gtttcttcaa agacaacctc aaaacaaagg gatcgaagag cttaggtctc cccttgctct
     4681 tcagatccaa acatgcgtca gaaacagtta gtattcaagc tgttttctaa catgattacc
     4741 ttgcttattt tgcttcgctt gccaataatt ggtctgcgta gattttttcc aatttttctt
     4801 gaagagctgc tttgattttt tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg
     4861 gtgtcattac gctggcacgc aatacagtta cttttccggc acggttccat tcttcatctg
     4921 agaatcctag ttggttcaca aattgtaatg ggctgttgcc atagtctggg atagcaaagt
     4981 cagtatgtga agttaagaac tcattaccgt aaatgcttcc tttcacgtat gaagaataat
     5041 catatacgtc atggttcaat ttattcattg caactaagtc atcgttgcct ttttctttga
     5101 atacatagtc taccatattg aaatctggat aagttaatgg atgaacttcg atttctttgt
     5161 ctcctacttt aaatgacaag tcattcaaga agttgtagaa acgatgtgca ccttcgattg
     5221 atgcacccat taatttacca tatcctgtga cattcaaagg taagacatgg tgtgctgccc
     5281 aaacgctggc tgctgttgcc cctgcttttg aaccttccaa gatataagcc ccaagtaatg
     5341 ctgggatatc tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata acgtctctca
     5401 tgcggatatc tttgatgacg ataccaccgg cagaatatgg aacatagccc attttatgtg
     5461 ggtcaatcgt tacagattct gcttcttcga ttgctttata cgcactgtgt acttcttcta
     5521 agatataatc tttgttttct gtaaagacat tgtatttgta atgaacatct tttaaatctt
     5581 caaatggaat gaagttgttg tcttcgtcta agaaaatcgc acggccgtat ccgccataag
     5641 cagcatctac gtgtaagtag aagtaaatac cgtctttttc taatacgcga cgcaatgcaa
     5701 cgattttatc gataccgtcg attgctcctt cttctgttga tcctacaaca ccgactacac
     5761 ctaggattgg tgttttttca gctgctagac cacgaacgat tttttcaagt tcgttgatgt
     5821 ccatgcgata gttgtggtca actggcactg gaatcacttg gtctaaaccg ataccgatga
     5881 tgtcggcagc ttttagccat gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt
     5941 tttctaaatg ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt ttttctggga
     6001 cgctgtctaa cagattcatg atttcttctg ttgacaagtt cattaattcc caatcgcttt
     6061 ttccagcaac tagttcaggt gtcacttctt tcattgcaag cggcaatgat ttgatgttgc
     6121 gggcatacca aagtccttct aagtttgcta aagaaccatc agcaacgatg tggccccagc
     6181 catctttata gctcattaat tttgcaaatt ccattcctac ttcttcttcc atttggcttg
     6241 ttgcaggaga agattcatag gcaacgttat taccattcca tagcatagca aaattgtacg
     6301 ctagtaaaga tggcatcaat gtttcagagt tcatatgacc ccagtaacgt ccggcattat
     6361 gccaaggaac ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt
     6421 tattcacagt gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata ataggcatgt
     6481 cttgaggcat gtagttttga cgccagccta aatgttcatc caccaattca ttcaacaaag
     6541 ctttatagat ttggccgttc tcagctttgt ccccaatgaa tagggcattt aggtttagat
     6601 ctttcgacaa tgattcactc atagtgaaac cctcctaaaa aaatatttaa attttgtcga
     6661 gccctacatt acacctgttc ttctattctg taaactaagt tttggcctga tttttaatca
     6721 tattttaata tgtatcaatt atccgaattg ttcacacttt tgaaataatt aaaaaaaacg
     6781 agggaattta caaatgtaaa ctccctcgca aagattgtat taacgacaac cagcgttcta
     6841 ttttaggatg ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa
     6901 acttactaaa ttctaatcaa ttactttggc caaaaagtaa tttttcttac cttttcgaat
     6961 aaccacaaac ttaccatcga attcatcgga tggatttatg acaaaattta aatcggtaac
     7021 gcggtcaccg ttaatactta tagctccgtt tgaaacatct tcacgtgctt gacgtttaga
     7081 tggttcaatt tttgtggaaa caagcagttc cacgatattt tcaggtgtgc ttgaaatttc
     7141 aacgttcggc attttaccga atccttgcgc gatttcttcc gcatttagtt ctttaatatt
     7201 tccagagaac aatgcttgcg ttattttttg cgcttctttc aagtcttctt cactatgcac
     7261 aaatcttgta acttcttctg ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc
     7321 tacttttttc gctaagtctt cgatttcttc ttgagacaag aaagtaaaga atttcaagta
     7381 tttcactaca tcgcgatcat cttgattcaa ccagaattgg tagaactcaa atggtgaagt
     7441 tttcttcgga tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc
     7501 cttcagcatc aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg
     7561 gattaggtct aatccagctg tgatatttcc ccattggtct gctccaccga tttgcaattg
     7621 cacatcgtat gttttatgca gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa
     7681 ctctgtaaat gagattccta cttccaaacg gctggcaacg atatcttttg ctaacatcgt
     7741 gttgatgttg aagtttttac cgtagtctct caaaaattca agtaaagaga tttttgacaa
     7801 ccagtcgtag ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt ttctcatttg
     7861 attggaaagt gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca cacgttctgt
     7921 tttgcggccg cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa tatatggatg
     7981 atggcctgcc aattggaatc ttttcatcat cataaatgga atcaaatgtc cgatatgcat
     8041 cgaatcacca gttggatcaa cgccgcaata aagtgaaatg ctcttttctt caacgagctc
     8101 gcgaagtctt tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta attcatcaat
     8161 aatattcatt ttactgacct ccgtgtagtt tttttatgaa agcaggaacc tgctagcatg
     8221 tgtaattaat tatttcttca ggataggata ggaaataaaa aaagtccctt ggcatataag
     8281 ccaagggacg aaatctcgcg gtaccaccca atttgtatgt ctagatatcc aacatacctc
     8341 tcgaacattt aacgctgtcg cgtggcaatc actgccaaag actcctgaaa tgtaattcgc
     8401 tttaaagcat gtactggttt gcagcgacca ccagctttct gaaacattgg ctttaacaac
     8461 tacttcgttt cgatcttcgt cttgttatta ttaatatgtg tctatcatag agcgcaactt
     8521 tttctttgtc aacagaaaaa ggatattttt tttaaattcc tcattttttc ttttttgaat
     8581 ccgctctaat tccgaacatt ttattttcaa ttattgttaa aagaaataac tttttctgta
     8641 ttttttctgc aatttatcga gaagtcactt tactttgcct cttattcttt cttcgttaca
     8701 ataaggaatg ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag
     8761 caaaaaatta ttttaggagc cacttctgct ttaactatcg ttattttaat tctaagtttg
     8821 ttttttgtca tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca
     8881 gaaaaagcaa aagaaccgac agatgataag caacaactag ttactcaagc aaaaaatctg
     8941 gctcaaagct acgattatga ccaagcgatt gcgttattgg aaaaagatag taagaacgga
     9001 tctactgaaa cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac
     9061 tggtctgatc ctactcagat ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa
     9121 aaagccttcc actctcaaca ggcacaagga tacaaagatt atatggtgac tgttgaagaa
     9181 ttcaaccgtt cgatcgaaca actttatcaa aatgattttg ttttagttaa tttgaatgat
     9241 ttgatccaaa aagacgaaca aggaaatctt tcctttaacg ggcttgcgct acctgaagga
     9301 aaaaaaccat tggttctttc acaagatgat gtcagctatt atgaatatat ggataattcc
     9361 ggttttccta gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag
     9421 aaagataaag aagaaatcgg tgactttgac atggttcctc tgatcgatgc ctttgtcaag
     9481 aaacatcctg atttttctta tcgaggcgca aaaggtacct tggccctgac aggttacaac
     9541 ggagttttag gttatcgaac atcaaaatct caatatggag acaatgaaaa aacaaaaaaa
     9601 gagattaaag aagctaaaaa agtggcggaa cagttgaaga aagacggctg gagctttgct
     9661 tcccatacat ggggtcactt gaatatgact caagcttcac tagaagatgt aaaaaaagac
     9721 aatgaattgt ggcagcaaga agttgcacct atcctaggaa aaacaaatat tctgatttat
     9781 ccatttggtg cagacatcag cgactggcag ccttattcag cagaaaatca aaaatttgct
     9841 tacttgaaga gtcaaggttt cgatattttc tgtaatgtcg atgcttctac accagcttgg
     9901 ggacaattag gtacggattt ctatcgaaat gctcggatca atatcgatgg cattcgtttt
     9961 caatctgatt tagacggaaa aaatcctatt cttgatccat tcatcaatgt ccatgatgtc
    10021 tatgacaaag aagcacgcga atctgcttga ttttacgtca tttatgaacc aaaaaagccg
    10081 aactgacatt ttatcgtcag tttcggcttt tttatgcttt atttcttctt cggtgcgatt
    10141 cccttgatca ggacttctgt ccattctgct gtatatggaa gcagttttgc gtatatctcc
    10201 ggcttagaaa ttccttctac cattgcttga aaatagagga tcaagaactc atccgaatat
    10261 ttcaaatcca cttttccttc tttccgccct cgatggaaaa gatcaagcat gatactgaaa
    10321 ctttcttgcg tatacgcatc catcgcgtca gaaaattctt ttttttcttt ttttgtatag
    10381 tatgtcatca aatcgatata aaattgtttg ttcactcgat tgagataacg gattttgttt
    10441 tcactcatgg caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct
    10501 tcttgcccta aatcattcat aaatgcaaaa aatacttcat aaatcagccc ttccttgctg
    10561 ccaaaatatt taaaaatcgt cgctttactt acctgagcgt tctcagctac cttatccatt
    10621 gtcactccag cggttcctat gtctgtgttc atcaagtcaa aagctgcttg taaaatctct
    10681 ttctttttct cttgtgctct cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt
    10741 aaacttttat aatatatata gttcaaattt attctgaggt ttattataac tatctattga
    10801 gaaagtatca ag
//
LOCUS       DAJSMK010000080        10760 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.083, whole genome shotgun sequence.
ACCESSION   DAJSMK010000080 DAJSMK010000000
VERSION     DAJSMK010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.083"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(59..1042)
                     /gene="istA"
                     /locus_tag="ON488_002093"
                     /pseudo
     CDS             complement(59..1042)
                     /gene="istA"
                     /locus_tag="ON488_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1437..2279)
                     /locus_tag="ON488_002094"
     CDS             complement(1437..2279)
                     /locus_tag="ON488_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HCR3232276.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2604..3020
                     /locus_tag="ON488_002095"
     CDS             2604..3020
                     /locus_tag="ON488_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCR3232277.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3017..3487
                     /locus_tag="ON488_002096"
     CDS             3017..3487
                     /locus_tag="ON488_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3232278.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3501..4274
                     /locus_tag="ON488_002097"
     CDS             3501..4274
                     /locus_tag="ON488_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3232279.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4288..5100
                     /locus_tag="ON488_002098"
     CDS             4288..5100
                     /locus_tag="ON488_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCR3232280.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5154..6119
                     /locus_tag="ON488_002099"
     CDS             5154..6119
                     /locus_tag="ON488_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR3232281.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6256..8979
                     /locus_tag="ON488_002100"
     CDS             6256..8979
                     /locus_tag="ON488_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCR3232282.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            8992..9624
                     /locus_tag="ON488_002101"
     CDS             8992..9624
                     /locus_tag="ON488_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HCR3232283.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9829..10056
                     /locus_tag="ON488_002102"
     CDS             9829..10056
                     /locus_tag="ON488_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011837604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HCR3232284.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10125..10391
                     /locus_tag="ON488_002103"
     CDS             10125..10391
                     /locus_tag="ON488_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HCR3232285.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10381..10650
                     /locus_tag="ON488_002104"
     CDS             10381..10650
                     /locus_tag="ON488_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCR3232286.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
BASE COUNT         3566 a         1716 c         2102 g         3376 t
ORIGIN      
        1 aataaatagt ttttctatca agtatattga actacgataa atttgttatt ttgttttgtt
       61 taatttcgtt gtacttattg gctttgactt cgatttcttt aaatactggg taatcggtgt
      121 ccggcaaagc tagcaaatct gttttttctg tgttccatag atcattgata atgacatgtt
      181 tttcgtaatg gattcgctct cgatcgtgtg acagctccac cgctaatgcc tcgttgaaac
      241 tggcgaaatc cttcataatc ggtgtagatg aaaagaagtt gtaccgtaca tagccgactt
      301 tgttttccat actacctttc tcgtttccgc tacgtggatt gcacacctgt gtctcaaaac
      361 catagtgcat agaaaatcgg aggaaaccgt cagtcagcac cgcttgttca gtctttgttt
      421 ttgtctaagt aacggccgtt gacatattat caatccgtat tttccgagga acgccacctg
      481 attggctgaa gagttctttc atgccttcca acaaacattc ttgattctcg gcggggagta
      541 caacggcgaa tcctgcatta ctaaaaggga aagtcatcac taataccttc acatctttaa
      601 acgctccatc gtgacaaact tccatcgtac caaaatcaag ttgcgcttct gctggcgggt
      661 gttcaagacg ctcaaagcct tggtcttcca gtgtttccaa gtagtgtgtc gctttccaat
      721 cttgaatgaa tacacagact gttcggtagg atcctggaaa gccatcggct tttaaagcag
      781 tagtcattgc ttcagcagtc ctacgctttt tatttggcag cttagcatct tctgaaagcc
      841 atagggaaac gatgcctccc cacttttctg tatacatcat accagtcttt ttgcgtgctt
      901 taggttgcgg cagcaaatca tcatctgcat attttttagc cgtgcgccaa tttacatcta
      961 gctcctttgc aatatgatta atggatttat catgattatt tcgtaaattt ctgatagtat
     1021 taatatcggt cattgtgagc atacctttct tacctccagt tacagtgtcg agactataac
     1081 tttagaggag tttcaggttg cccgcaatgg ctttttatct taacttaatc gatttgcgga
     1141 gttgtgtagt ttttcgttgc acttgtatgt acttttattc tgccataaac agcttaatga
     1201 atgtccactt gaaaaagtga ataaacgaaa tagatgactc gatttaataa ggaagtaaac
     1261 ccacacagaa atataggtga ttttccttga atgaccaaga tattgaaagt tagtgaaaaa
     1321 acacaaaaag gtagccctat tcacagaagg tctgcctttt gtgttatcgc cagcaaacat
     1381 tagagggggt atttcatata gcttttgtcc tctcgacagt cctatcagtt tctcttttaa
     1441 cttatctcta agtgctgtcc agttttaata gcttctagct tgtttcctaa ctgtgttttt
     1501 aatatgttga aggcttttga acctgtgcag tggcaagtaa ggattttttc tactcgtgag
     1561 tcattcaatt tatttccaat tttcattacc tcttgctcag gtagacctaa attatttata
     1621 taaggtatgc caatcatatg gaagccacca attaggtatt ttatgggttt agtcggaaat
     1681 gtttcaagag caatttccat catatcgata atgccatgat gactacagcc agtaaagaca
     1741 atcagaccgt cttcttgctc aattacgacc aataattcat ctgaaaaatc atcataaaca
     1801 aatttatcat ccatcttttt gtataaattc ttggtggtcg agtttgcttt gcctaggggg
     1861 atgatatgga agctcggagc aagttctgtt ttcgttttta ttgtatgtaa attctcatgc
     1921 attttaagga tttcattttt aggaatacca acatacagaa acgtggttaa aatctttaaa
     1981 taatggggta aagttacacc ttcagctgta taaatagggg cgtttcctga ttttaaatat
     2041 cttaacccgc cggtgtggtc agaatgaccg tgtgaaataa tcactgcctc cagatcattc
     2101 aaagtttccc ccattttagt cgcattatag actaattttt tattagcgcc agcatcgaag
     2161 agatatttct tccctgagta gttaattaag agagataacc catgtccact tttaaagttc
     2221 aaatttattc ttgagttttc aaataaaacc ttgatttcca ctataacatc tcctttcaca
     2281 tgaacgtgta ttcatatatt gtagcacatt aagttctatt ttttgttgta attaccgaaa
     2341 aaaatattaa tggacgcttt ttacgcttta tttcgtatgt ggaagaaaat ttcttaggat
     2401 gtggcggggg attggggcaa agctaaattc caattacagt gatcatttaa ttagacacct
     2461 ttaaataccc acactttcat caacactata atttagggaa agaaaagtgt tggcatgata
     2521 tagaaaaacc tttaattaac agcgtttcct aaaattggca cgcatcttgc ttatagaaaa
     2581 gcgtaaggat aggaggaatg aaaatggcaa ctataattct tgccagccat ggggaatttg
     2641 ctcaaggatt aaagcaaaca gcgacaatga ttattggaga tagtgtacca attcatgcct
     2701 tgtcagcatt tagagatgaa gatgaatcta ttttggtaca aataaaaaaa cttttagcca
     2761 caatagatat agaagaaacc tacattttaa ctgatattct aggtggtagt gtgaataatg
     2821 atatgctcac tattattaaa gagtatgagg gattgcaatt aattactgga atgaacttac
     2881 ctttagttat ttctattgca acctataatg gaaaaattgg ggaaagtgag ctagaaaagc
     2941 ttattaaaga gagtcaacaa tcagtgattg attgtagaaa attattagta gaacaactta
     3001 ctggaggaga tgacctatga ttaagttagt acgtattgac catcgtttgt tgcacggaca
     3061 ggtagtattt tcttggagta aatcattaaa tatcaatcgt attattattg ccaataaaga
     3121 ggcagcgaat gatgaattca aaaaaatgtc tttgaattta tctaaaccga ctggcattaa
     3181 attaacaatt ttttcagttg aacagttact agaaaaaatg cctaaaatcg aaacacttaa
     3241 cgaaaatatc atgcttattt ttggtaatac aaaagaaatt cgtcaatttt gtgaagccta
     3301 tcctaaagta caagaaatca actatggagg gataatcaaa aaagaaggtt ccaagcaatt
     3361 tagtaatgcc attttcttga atgaatctga gcaagaagat gccaaaaaat taaaagctct
     3421 tggcattaaa caatttattc aacaggtacc aacttctaaa aaagaagatt tgaatacaat
     3481 gttataaagg aggaatgaaa atgctcgttc agtcaattgg tttagggtta atcggtgttt
     3541 tttgtatttt agactcaagg cttttaggaa gaatgaattt tgaacgaccg ttgattgtca
     3601 gtacgcttgt tggtttggta cttggagaca tggaaaaagg attaattgtt ggagcctctt
     3661 tggaattgat gtccttagga ttagtaaata tcggagctgc ttcaccacct gatatgaata
     3721 tggcatcaat tattgctaca gcctttgcca ttttatcaaa tgcgaatgca gaagcagcat
     3781 taacgattgc cattccaatt tcagtgttag gtcaaatact aggtatctta atgcggacga
     3841 ttttgtcaaa tttgactcac gttgcggatc gctttatcga acaaggaaaa tttagccaag
     3901 caaggagaat tcatatactt tatggctcgg gattatatgc tctcatgtat tttattccta
     3961 tttttctagc aatttatttt ggaacgaatc ttgtttctca gattgttgat gcgattcctg
     4021 agtggctaac aaatggctta acggttgcaa gtaaaatttt accagcatat gggtttgcgt
     4081 tgttattaca aacgatgtta acgaaaaaaa tggtgccatt tttattactt ggatttttaa
     4141 ttactgctta ttctggattg ggaatcattg gtattgcagc cttcgcatgt attgttgcgt
     4201 ttgtcatggt tcaagttcaa ggtaaaaact caaatggtaa ccaaaatgag ccagatccat
     4261 tagatgactt ataaggaggt agattaagtg aaagagaaag atcaaaatgc atggaaatat
     4321 cggcagttct tatggcgttc atgggcaatt caagcctcat ggaactatga acgacaaatg
     4381 aacatgggtt ttatgtacgg aattgcacca attctagata acatttacaa gaatccagaa
     4441 gatgaagcaa tgaagaaaga agcttacgag cggcatatga tgtactacaa ctgtacccct
     4501 caaacaagtg catttgtgtt agggttaact gcttctatgg aggagcaata ctacgaagac
     4561 caagaaaact ttaatccgga atcaatcagt gcagtgaaga cttctctgat gggaccgcta
     4621 tctggtgttg gtgattcttt ctttcaagga acgattcggg tattagcctt tggactagga
     4681 attaatttag cccaacaagg tagtatttta ggtccaattc tagcaatgtt aatttccttt
     4741 gtaccttcct ttttagttac ttactatggt gggaaaattg gctataacat ggggaataaa
     4801 tacttgtcta aactgtatca agaaggtttg atggataaag taatgtatgt ttgctccatt
     4861 gtggggttga tggtcattgg ttcgatgatt gccagcatga tcgggattac aacaccaatt
     4921 caaatgggta aagcttttgt cttacaagat gtattagata gtattatgcc acaattttta
     4981 ccattaggat taaccttctt catgtactgg ttattgcaga aaaaggtcaa aacaggatgg
     5041 atgttggcaa tctgtttagt cggaggaatt atttttagtt tgttaggtat cttacaataa
     5101 gggaataacc aataaatttg gttgaataat ataaataagg aggaattcaa ttgatgaatt
     5161 caaaagaaat tgttaaagaa atcgtagcga aaaaagaggt aaaatcaatc gtatttgttg
     5221 gctgtggcgc ttcaaaagcg gacctttatc ctgcaaagta ttttctagac caaaatgcga
     5281 agcagttacg gattagtcat tacacagcca gcgaatttaa ctatgcaaca ccagcatctg
     5341 tagatgagtc aactgtcgtt atttcagctt ctttaggagg tacgactcca gaaacagttg
     5401 aagctaacgc agtagctaaa gaaaaaggtg ctacagttat tagtctaaca cgaagcattg
     5461 actcaccgtt aacaaaagat gcagattatg taatttatca tcgatttgca gagaactatg
     5521 ctgctaaatt agaaaaaaca ggctactgtt tagaattggc agtagaactt ttacatcaag
     5581 tagaaggtta tgaccattat gaagcaatgc aagaaggatt tgctactatc tatgatcttg
     5641 cccaaaaaag tgcagaatca gctcgtaaag atgcgaagaa atttgctgaa cgctttaaag
     5701 atgaaaaagt tatttatgta atgagtagtg gtgctacaca tgaagtagca tactcaacat
     5761 caatttgctt gatgatggaa atgcaatgga ttaattctgg taccttccat tcaggagaat
     5821 ttttccacgg accattcgaa attgtggata aagacgtacc gtttatatta ttaatgaatg
     5881 atggaaaaac tagaaatata gatgctcgag cattaacttt ccttgaacgc tttgatacga
     5941 aaacagaagt tgtagatgcc ttggattatg gcttgtcttc acatattgct aaagaagtct
     6001 tagactactt taacccattc gtgattactg cagtatttag agtttatgca gaagaattgt
     6061 cagaagcaag agaacatcca ttaactaaga gacgttatat gtggaaacta acttattaaa
     6121 aaatagatca aactaaataa ggtggcttga gaaattaagc caccttgttt tcttcaatgt
     6181 gattttatac atatggtaaa ataactagta catatggtaa aataactagt acatattgtg
     6241 aaagcaggtg gcaagatgca gcgattaaat gactatcttt atcaactaac attgcttttg
     6301 aaatctacgc cttcagataa ttattcagct cgcagtattt cgcaagctct acagttgaat
     6361 agaagtacaa tcagtagcta cttaaatgaa ggtgttcgtg aagggctttt cataaaagta
     6421 aaaagttacc cggttttatt tttacataga acagctcttg aagaactaca tatcacactg
     6481 aataactccg aaatagaatc aattgaaagc ttgttaacaa tttctcaaaa acccgcatta
     6541 gatcaagtaa ttggctctaa aggaagtttg aaagaagcaa ttgatcaaat taaaacggca
     6601 gtcttatatc ctggaaaagg gttgccttta ttattgatcg gcgctagtgg atcagggaaa
     6661 acctttctag cgaataaaat atatgaatat gcagtagaag aaaaggtcat tcacacatcg
     6721 gcacctttca tagattataa ttgtgcacaa tatgtgagca atccagagtt actatcctct
     6781 gctttatttg gctacacgaa aggagcattt accggagcaa gccaggagca tactggtttg
     6841 ctagaaaaag ccgatggagg agtattgttt ttagatgaag tgcatcgctt atctgaagaa
     6901 gggcaagaga aattatttac atttatggat acgggtgaat tctctcctat gggggataat
     6961 agtattcgga aaaaagccga tgttcgatta gtctttgcaa caacagaaaa tatatatacg
     7021 actttcttac caacttttct taggagattg ccagttattg ttaatctacc tagatttcaa
     7081 caacgtccgt cgtttgaacg tctgtcattg attgatgaat tttttgtttc tgagagccaa
     7141 attttagcta aggaactatc tgtttctgat gcattgattc atttcttaat gaatagtgat
     7201 tttgaaggta acgtggggaa tattaaaaat attatcaagt atgcttgcgg aaacgcatat
     7261 atccaccaga agagtcagca aacaattcaa gttaaattat tggatatgcc tttagagtac
     7321 agttataaat tcaaggagca actaaataaa cccagaaaga aaagagcaga tcgaatctac
     7381 tatccagaag aaacacgaca agtgcaacta gaaagaaaca atcagctttt tgttcaattt
     7441 tttgaccaat tacttactgg attctctgaa gtgattgaaa ataacaagga tattaaacta
     7501 tttttagaag aaatggttac caaggtaaca caagtaatgg atacgcttat ttttcaagag
     7561 gattacgaaa aagagcagtc tttatacgcc attctaaact atcatattcg tcaaagtatt
     7621 gattttatgc gagaaagcta cgggtttgaa caagatggta accgggtagt cgctttggcc
     7681 aactatctat atgtcaagga taatcaagtg atttttgaaa atagtcttca agaaaagaaa
     7741 accaaagatc agcttaacga attttttgct aatgttcttg aaacccctta ttggtatgca
     7801 aaaaaaatct taagcctttt atctgagtgt ttagatcaac ctgtgtatga agaggacatt
     7861 ttctttatta cgctatattt ttatagtttg aatgtcacga atgttaaaac aggtattaag
     7921 agtattgtgc tagctcatgg ttattctaca gctagtagta tggcgaatgt tgccaaccgt
     7981 atgctgaata agaacgtttt tcaagcttat gatatgcctt tagatattac attagagaaa
     8041 attgaagcaa aattgattca attccttgga gattatcgaa cagattcagg cttgatttta
     8101 ttggtagata tgggttcact aaaccaacta ggcggtttat tagtgaatca tctaaatgga
     8161 ccactgttaa tcattgatca tatcaataca ccgttattat tggaagtcgg ccaacaagta
     8221 ttaaacaata aaagtatcac cgaaatagga gcagaaattg aaacaagtct tactttcaaa
     8281 aagcagttac tacttcccaa gaaaaagaaa aagaaagcca tcattacttg ttgttataca
     8341 gggattggta gtgcgaccca gattcaggag attttaacga aatgcttgaa agatgcagtt
     8401 agagaattag taattattcc gtatgattac aaaaagctgt tagaaaacaa gaattttgag
     8461 actccttttc aattatacga tgtcatcatg attgtaggta cagaagatcc caaaattaat
     8521 cagattccat atattggatt agatcgcctg attaatgggg gaagcattgg cgaatttgtt
     8581 cattacttgg aaaaagagct gactattgaa gtgaacgatt tacaaaaaga attaattttc
     8641 aatttttcaa ttagtaaaat tgtcgaaaat ttaaccattt tggatccaga taaggtgcta
     8701 tcttttgtac aaaaagcaat taaagaatta tcgaagttat taaattttga tttttctaat
     8761 aatcagctgt ttttgttgta ccttcactgt agttgtatga ttgaacgaat tgtacgtaaa
     8821 gaaagtgtgg atgagcaaga ggacattgaa gaatatatgc aagcaaatgg agaaataatg
     8881 gataaaattc atagcgcttt ttttgagatt gaaagggaat acacaattga aataccagat
     8941 ttagagttgc gattattgag cgatattgtt caaggatagg agtgaattcg aatgacaatg
     9001 ggagtaattt ttgatatgga tggggtactc atagatagcg agacatttta ttttgagaga
     9061 agaatgaact tctttcaaga actggagata gatccaggat caaaccagat tgatgattat
     9121 gtggggaaaa cagaagctgc aatatgggaa acattagttc ctgaggacaa atcattaaga
     9181 gaggaacttt atccgaaata tgtagattat cgaaaaacgc atccaattga tttcgctaaa
     9241 gctttacgaa aagaagtgaa accgttactt gacttcctca agaagcggga tataccattg
     9301 gcactggcat cttcttctcc agctgtcgag atagagagta tgctcattca atgtgaactt
     9361 actgaatatt tttcctttgt tataagtggt gagtcattaa aacaaagcaa accacatccc
     9421 gaaatatatt taaaagcgaa acagcaatta gactgtgact tctttattgc agtagaggat
     9481 tcaacgattg gtattaaatc agcaaaggca gcaaatatct atacggcggc actaaaacaa
     9541 ccaatgcaaa tcgatcagag tgaagcagac atacaaattg aaagtctaca agaactggaa
     9601 caaattgttt tagaaaaagg ttagtgaatt aatggaaata aggctatata tctgtgctag
     9661 ctattttgac taaccaaaaa aacttgctat aattcaggtg tagtaaaagg tgctggtaac
     9721 accttttacg aaaatgcttc ggcagtgata atgggattgg ctttttaagt tttttatttt
     9781 gttcgcaatc cctaaggtca tgtgaatgat cctagggatt gctagaatat tttgcaacag
     9841 aaccaaaata cgaatagtta tcaagcagcc atattgactg cggtcaattt aggaggggat
     9901 actgatacta ctgctgccgt aactggtgct cttgcgggta ttctttacgg gggtgaagtg
     9961 atccctgaaa attggagaaa atcgcttcaa aatgaccagc ttcttaaaac gatcagtcag
    10021 agattttgcg ataccgtgct atctcaaaga atttgaataa tggatatgat gcaaatcttg
    10081 tttgtactaa cgttgtattg acaaaaagga ttttatttag tacaatgtta gtacaaatga
    10141 tgaacggagg tagaatcatg tctcaatcaa ccattacatt taggattccc gacgatgaaa
    10201 aagaactggt attagaatat gcaaaagcac acaattcttc attgaccgaa ctttatcgaa
    10261 atgctgtact ggataaaatc gaagatgaaa tcgatctacg gactttacgg agtgcaattg
    10321 aagtttccaa agagaaaaaa gagagtggta tttctcaaga ggaaatggag aaactgctaa
    10381 atgaattata aagtcatcta catgccgcaa gcccagaagc aattaaaaaa aatggacaga
    10441 aaccaagcta aaataattgt cgcctggatc agaaagaatt tagaaaacac gactgacccg
    10501 cgtcagcacg gaaaaggttt gactggaaat aagagtgggg aatggcgcta tcgaattgga
    10561 aactatcgaa tattggctaa tatttgtgat tctgaaattg aaatccagat attctcaatt
    10621 ggacatagaa gtacaatata taaaagataa ccgtttttgg aacgaagtag agtttcgaaa
    10681 gtcaatgtat aatcttttga attttgcata ataccacagg tagaaactac ccgatactat
    10741 cggttggttt ctgctttttt
//
LOCUS       DAJSMK010000081        10585 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.084, whole genome shotgun sequence.
ACCESSION   DAJSMK010000081 DAJSMK010000000
VERSION     DAJSMK010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.084"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(128..1402)
                     /locus_tag="ON488_002105"
     CDS             complement(128..1402)
                     /locus_tag="ON488_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HCR3232287.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTLEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            1710..2516
                     /locus_tag="ON488_002106"
     CDS             1710..2516
                     /locus_tag="ON488_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232288.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            2528..3748
                     /locus_tag="ON488_002107"
     CDS             2528..3748
                     /locus_tag="ON488_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232289.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGIVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     NKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            3738..5324
                     /locus_tag="ON488_002108"
     CDS             3738..5324
                     /locus_tag="ON488_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HCR3232290.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVVQTSIAQPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSEAT
                     ERMVFRFAQQPSFIEFSAEAAGEKLIFIDSNAVVKTVNDCYLFDGKEIPEFALTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENQHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKKTSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSRDEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            5363..7501
                     /locus_tag="ON488_002109"
     CDS             5363..7501
                     /locus_tag="ON488_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR3232291.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKIRLSGKMRGKAILDFQTAKHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKTIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNIHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKKLGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPSYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            7789..9180
                     /locus_tag="ON488_002110"
     CDS             7789..9180
                     /locus_tag="ON488_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCR3232292.1"
                     /translation="MNKNGEWNAARRIFIIIMDVLVLNVSIYLSFLLKFQGEVPARNL
                     ETFQHSAVFISIIFIALNILLGAYVFYSRVISDIVFITVIGQVLIALGIMVVTFAGRW
                     FAFPRGVIVLSFILGTILLSVYRIVVYKLYLRVSRDKKVLIVGLEKDVAPAIQNFQSK
                     KNNKHKVEAVVIDKYYENTKKLIDDIDIVYLASKIPEDEKINIYQLVTKKEKKLFLNT
                     TFENLTMINPNIMNFEDESIIEASGFKIQPEYELFKRLFDIIVSLILLILASPFMLIT
                     AILVKTTSPGPIIYKQVRITKNQKEFSIYKFRSMSVTAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNEENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLLLDLKILLQTIKILFDKMSSQGLDEDENIRS
                     LAEIDFSQEKIYR"
     gene            9239..10048
                     /locus_tag="ON488_002111"
     CDS             9239..10048
                     /locus_tag="ON488_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR3232293.1"
                     /translation="MLLSLYDKEKPEYLKEALTSIFEQTVMPKEIVLVYDGPINEKLQ
                     VVVTYFQQKDPHLFTVVKLEKNQGLGIALAIGLEHTKNRLVARMDTDDIMEPQRLEKQ
                     LEIFQKDPEIAIVGSNIEEFTGTLSNVIGRRIVPEYNDEIRVFSKRRNPFNHMTVMFD
                     KNAILEVGNYRPLIGFEDYYLWVRLLKAGYKGYNIQEILVHARAGADMYARRGGSKYL
                     LPGIKGRYRVWKDGLGSLKDFLIVICGHLVISLLPNKIRGKVYESKLRKTN"
     gene            10020..>10585
                     /locus_tag="ON488_002112"
     CDS             10020..>10585
                     /locus_tag="ON488_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR3232294.1"
                     /translation="MNQNLEKQTKLSIIIPFYNAKNTLKRAVDSVLTQGYPNIEILLI
                     DDGSTDGSSDIGDEIANLESKVACYHLENAGPSVARNCGIKEATGNLVGFLDSDDYFL
                     PDCFNNVLKDYHRNYPDIIAFGLSKGKNIENANLFVPEKKIGCSSEEAIEQMFRSKAV
                     DFYVWNKFFKRELFNHIVFPENKLYEDMV"
BASE COUNT         3543 a         1688 c         2161 g         3193 t
ORIGIN      
        1 aaaatacgag agaggctgtg acaaccgtcg cagccttttt tggctcttcg tcaaatcgtg
       61 ttggtgaaga caaatttgaa taaaacttag tccgatatgc ggcgcgttct gtgcgccgca
      121 tattttttta gttttcaaag atcagacctt gttgtaaata gatccgtgcc cgaaagttat
      181 aaaagttgcg ataaccaaac gcaattcgtt taatcagctt gatcttgtta ttcagcccct
      241 cagtgacgcc gtttgagtgg gacaccttaa aggcatttga aatacccgat tggtagcgat
      301 ggaagatcgt gaatttcttt ttaaacgact gaggtaacgt agatgaaatt gttttaaggg
      361 tttcttgaaa gccttccgta cctcgtttaa cgaaataata gcgtaataat tgacaaaaat
      421 gatacgcagt tcgcaattct tcgttgtagc ttaacagctc atcaacgatt tctgtttgac
      481 taattggtcg tttaaacagt cgatgataat gccgtttgag tggctccaat gtcgtggaat
      541 ctttgagtaa gagtttccaa tatcgcttga gccgacggta cttcttctga ttttcagagt
      601 gtgaggttcg aaaacgattc atgatctgga cacgtaattg attgaagctg cgattgatgt
      661 gttggacaat atgaaagcgg tcagttacga tctccgcatt tggaaagact gttttaagca
      721 actgacaata gctggcattc atgtccatca ctaggtactt gacctttaaa cgggcttttc
      781 taggaaagcg caggaagtat tgagttagtt tgtaaagtct gcgatcttca aggatcgtaa
      841 atagctgatg ggttgtccca tcaacacaaa taaaactcat ggaaccagaa acagacttca
      901 ttgatttgaa ctcatccata cacaacaccg tcggaaggaa gttcatacgt ggctggtaat
      961 gcttcgttgc ttcacgcaag atccgtgtca ccgtcccatc cgagacgaag tacttcttag
     1021 cgattagttt acgtgattga ttttcgtaca gttccatgag aatcgcctgc ttcagttcct
     1081 ttgttagttg atgatgttca tcaactaagt ccgttttcgc agaaaaggtc cttccacaat
     1141 catggcagag aaaacgggta cgttttaatt ctaaaatagt taacttttct ttgactttca
     1201 acatctgagt gcgtgtcgta taggaaccgt tgcggataat acgaaccgat cgacagtgtt
     1261 cacaatagga aggagagtca tccaattttc ctttaataaa ctgcgcttga acgcctttat
     1321 attctttttc aatcagccat tcttcatcaa aaaataaatg tttatctgtt aatccgagta
     1381 attttctagt atgattatcc attgagagac tcctttggta ggatgacgtt ttggtcgact
     1441 aaattttacc aaaagtgagt ctctttttga gtttaaacga agaaaaagtg ttagtagaaa
     1501 atcgccttcg attttccacc aacacaaaat attatagaac cccttttttg gtttattgca
     1561 attgtctagc atcttctgta aaatagaaac gttagagaaa atcttgtatc atagaaaatt
     1621 aagaaagaaa taagaacgca gctcggtacc aaaaatatgg taaaatggca cttgactgta
     1681 attcactgaa atcgcttgga ggaacacaaa tgtttaaaga tttgtattta tttatgaaag
     1741 acatttatca gaatagaaaa ttactgctac agttttcgat caatgacttc aaatcaagat
     1801 atgcaggatc gtttttagga atcttatggg cgtttatcaa tccgctattt actgtattga
     1861 tttattggct ggtatttggt gttggactga aagcacaaat gatcgatgca aaatacccat
     1921 ttatcgtata tttagttacc gggatgattc cctggttctt cttctcagat gcatttgcat
     1981 caactacggt tgtttttcgg gaatatactt atttagtaaa gaaagtcgta ttcaatattc
     2041 gtatcttgcc cacgacgaaa atcctatcca atctgtacac ccatttattc ttcattctga
     2101 ttggcatagc tgtcgcgctt ataaatggta tatatccttc agcaatgtct ttacagctga
     2161 tttattattt attttgcatg tgtgctttct tgacaggatt gacttggctg acggcatcga
     2221 tccaaccatt tttacctgat atcatgcaat taattacgat cgtgctgcag ttgatcatgt
     2281 ggacattacc gatattatgg agccctaatc agtttgattc aggtcttgta agcatattga
     2341 aattaaatcc gctgtactat gttgttcaag gttatcgtga gtcattttta agtgaagctt
     2401 ggttctggga gcatggaaca tatactttgt atttctgggt tttcacgtta gtaatgttcg
     2461 taatcggctc tgcagtgttc cgtagattga aaccacattt ttcagatgtg ctgtaaggag
     2521 aatagctatg acagaatatg caattagact aaaagatatc acaaaatctt ataatatgta
     2581 cgcaaaacct tcggatcgat ttcgtgaagc cctcaatcct tttaagaaat cctatcatga
     2641 tgtattttat gcgttgaaaa acgtgaatgt agaaataaaa aaaggtgaga tgatcggttt
     2701 cgtgggagaa aacggatcgg gaaaatctac aatgttgaaa atcattacgg gagtactgac
     2761 accaacatcc ggcacgatgg aaatcgaagg aaaaatctca gctttgctag aactaggatc
     2821 aggattcaat cctgagtatt ctggctatga aaatatctat ttaaatggaa tagttctagg
     2881 attttcaaga gaagaagtcg atgaaatggt cgatgatatc attgaatttg ctgatattgg
     2941 cgaccatatt tatcaacctg taaaaaccta ttcaagtggg atgttcgttc gtctagcttt
     3001 tgctgtagcg atcaatgtga atcctgatat tttgattgtg gatgaagcat tggcagtagg
     3061 agatcttgaa ttccaactga aatgtatgga aaaatttaca gaaattaaga actcgggaaa
     3121 aacgatttta ttcgtttctc atgatattag ttcgattcgc cgtttttgtg atcgttccta
     3181 ttggttgaaa aatggagaag ttgtcgaata tggtgatacg atggaagtaa cgacgaatta
     3241 cgaaaacttt ttgaagaaaa aatcagttaa aacagtagat cgaaataaaa accaagtaga
     3301 acgcttcgca gctccagata tcgtagacgt gacgaaagcc gaattgttgg ataaaaataa
     3361 aaatccagtg gatatgctgg aacaaggaga aaaactatac gttaaagtaa cctatgaagt
     3421 aaaagacgat acaatcaaaa atccagtttt aggaattgct ctgcgtacag tcgacaattt
     3481 ttatgtgtgc ggactcaata ctctactaga tggtatcaag atcccttgga aaaaaggtga
     3541 gaatatcttt tatctggagt atgaaaagtt aggtttgtta gctggtgaat attattttga
     3601 cgttgcggtc tttgaagaaa atgcaacggt tcctttggta tacaagacaa aatacatgaa
     3661 cttgtttgtc agcggttctt atatcggaga aggcatcgtg gtcttagacc ataaatggga
     3721 agaagggact catagcaatg aaatatgatt ttgaaatgga cctagatgaa caaagcagtg
     3781 tgggaaaaat tgccgcacag atcaaaccag gaagtaaagt tttagagttt ggtcccggaa
     3841 acggtcgatt aacgaaacat ttgatcggag caaaacaatg tgaagtgagc attgttgagc
     3901 tagataagga attattcgat tttgtcagcg aatttgccca agatggattt tatggagata
     3961 tcgaaagttt tgaatgggca aactattatg ctggacagac atttgattac gtcttgtttg
     4021 cggatgtttt agaacattta gtagatcctg gaaaaacatt gaagaaagtc agagaatttt
     4081 tgaatgaaga aggagagatc ctgattacat tccctaactt agcacataat tctgtcatga
     4141 tcgatttgtt caataatcaa ttgccttggg cttcttatgg tctcctagat gaaacccata
     4201 attcttttta tactcatgat ggtttccaaa aagtttttga aaaagccgga ttattcatta
     4261 atattgaaga ttacttgtac ttggctgtag gagatacaga attaaaatca acttatgaag
     4321 agttgccgga agctgtacgc tatgatttca aaatgcgacc atttggtgaa gtctaccaat
     4381 actttttctc attgatgaaa catccagtag tacaaacttc cattgcacag ccacaaaact
     4441 ctaattatgt aaaagtacta gaagtaaccc agcaaacgaa acaagatgaa acaatccaac
     4501 aaataccatt caataatttc acaggggaaa atgagacact aagtttcccc gtgtcagaag
     4561 caacagaaag aatggtgttt cgcttcgcac agcaacctag ctttatcgaa ttcagtgcag
     4621 aagctgctgg agaaaaactc atatttatcg attcaaatgc tgtagtcaaa acagtaaatg
     4681 attgttattt gtttgatggg aaagaaatac cagagttcgc tctaacggat atttctggga
     4741 aagaagtgac tatccattgt cactatcgct ttatcgggga attgacacca acaatgaaag
     4801 aattgctgga aacaattcgt cctatggctg aagtcacaaa gcagctttct gagaaaaatg
     4861 atgaattaga aagagaaaat cagcatcttc ttgaggaaaa tacaagacta gaccatacgt
     4921 taaaaacaac cacaaatcgc tattgcacat tgttggaaag tgatgaatgg acgatcaaac
     4981 atagactagg acgacgtaag aaaaaaacat cgaaaaaaat acaagaaaaa gagctttcta
     5041 tatgtattga tgagaaaata tgggatgcag aaacaaaaat attaaaaatc atcggatggg
     5101 gaatcgctaa ttcggatcgc cagccattgt cctataagtt atcagctgac caatcgccat
     5161 ttttcgaagc aattcctgtt tcacgagatg aagtcaatca agcagaacag ctcgcaaaag
     5221 gaacagaagc gggatttgaa ttacgaatcc tttgcgagca agaacgttca ttcttagtgg
     5281 aagcagtagc tcaaaatggt caatcatgga tcattgaaat gtaaataatg attaacttat
     5341 aaagataagg agtaaacgaa tcgtgcaaaa aaaagaaatt gccgtattta tcgatcaaat
     5401 cactcgtgaa cgggccactg gcgatttgct tattgtgggc tgggcaattg atgaagtgac
     5461 caaagaaatc cctacgataa aggtagaaaa agaaaatgtg attgctgaag caacacatgt
     5521 cgtaagattg gatatcaatc atttatataa tcttgatgtt aagacccaaa gcggttttaa
     5581 gatacgttta tccgggaaaa tgagaggaaa agcgatctta gattttcaaa cggcaaaaca
     5641 tcaaaatggc atagctgtga aactaaatgg taaataccct tatgatgacg gcattgaatc
     5701 ttcatgggaa agaaaaaaaa gattactgaa aaaagggata aattatgcaa ggactcatgg
     5761 cgtaaaaaaa acaatccgcc gggtcaaact ggaattgaaa ccaggatcga tcgactatgc
     5821 agagtggatc agtcgtcacg agaaacctga tctgaaagag caaaggaaag aagcacaagg
     5881 gtttgcatac cgtccattga tttccatact tatgcctgtc tataacgttg aaatcaaatg
     5941 gctcgaaaaa tgcattgatt cggtattgga tcaaacgtat gatcactggg aactatgtat
     6001 cagtgatgat gcttctactg atccagctat ccgaaagtgt ctggaatcct atcaagcaaa
     6061 ggatgataga atcaaagttg ttttccgaca agaaaatgga catatcagtc tggcaactaa
     6121 ttctgcgttg gaaatggcag aaggagaatt tatagcgctc ttagataatg atgatgaatt
     6181 accgccattt gcattatatg aagtggcaaa agtgctaaac atacatccag aactggattt
     6241 gatctacagt gacgaagata aaatcgatgc agatggcaat cgctttgatc cgcacttcaa
     6301 agcagactgg tctcccgata cattgatggg aaataattat atctctcact taggcgtata
     6361 tcgaacaagt attgtgaaaa agcttggcgg tttccgtaaa ggctacgaag gctctcaaga
     6421 ttatgatttg gtccttcgtg tgacagaaca aatccctgca gatcatattt accatattga
     6481 ccgagtcttg tatcattggc ggacgatccc aggatcaacc gcaagtaatg gtgaagccaa
     6541 aagttatatc tatgattctg gagtgaaagc attgacagat gccctgtcta gaaggaatat
     6601 caaaggaagc gtacgtcctg gcagaatttc tggattttat gagattgctt atgacgtctt
     6661 gcaagaggat ttggtcagcg tgatcattcc aacgaagaat ggctatgaag atctaaaaac
     6721 ttgtgtggat tcgattatcg aaaaaacgtc ttatccaaat tatgaaatca ttattgcaga
     6781 taatggaagt acagatccta aaatgcagga attatttgca gaatacaagc atcagctgaa
     6841 agaccgattt atcgttgaat taattgacat tccattcaat tattcacgta tcaacaatct
     6901 ggcagcagaa aaagcaaacg gcaaatactt tttattcttg aataacgata cagaagtgat
     6961 tgaacctgac tggatgacag cgatggtttc ttatgcacag tttgatcgaa tcggctgtgt
     7021 aggagcaaaa ctgttttatc cagatgatac aacgcagcat gcaggagtat tattaggaat
     7081 cggtggtgtt gcaggacatg cattgaataa ctatgatcga acacattgtg gttatttcgg
     7141 ccgattggtc attgacgtca attacttagc agtcactgca gcttgtatga tggtcaaggc
     7201 agctgacttc aatgctgtca atggatttga tgaaacatta gaagtagcat tcaatgatgt
     7261 tgacttgtgt ttgaaagttt atgaactggg tcgttacaat gtctatgcac atcaagcaga
     7321 attgtatcat ttcgaatcta aatcaagagg ttatgaagat acaccagaaa aacaaagacg
     7381 ttttgccggg gaaataaaaa aaatgcaaga taagtggcct tcttatattg ctcatgaccc
     7441 attttataac gataatctaa ctaaagaagg aatcggcgat ttttcattga gacctgattg
     7501 attaaaagaa ctgtattttc atttttattg atgaaaatac agttttttta gtatatgaaa
     7561 attgtaactt gtgaccgaag agatgatagg aagaacaccc attcagtagg aagaatgtga
     7621 tacgattttt gtccaactct ctgttaggca gaaatataca tataaacata caatagtcac
     7681 cttttctagt ttcttttaat ttattttaca atttggttat tcactaggtt tttaaacttt
     7741 gctatggtaa gatgatagag gcattatttt atggttagga gtgtatatat gaataaaaat
     7801 ggggagtgga atgcggcacg taggatattc attatcatca tggatgtact tgtattgaat
     7861 gtgtcgatct atcttagctt tttgctgaag ttccaaggag aagtcccagc aagaaactta
     7921 gagacctttc agcattcagc agtttttatt tccattatct ttattgcgtt gaatattttg
     7981 ttaggagctt atgtattcta tagccgagtg atcagtgata tcgtcttcat tactgttatt
     8041 ggacaggtgc tgatagcatt ggggatcatg gtagttactt ttgctggacg ttggtttgca
     8101 tttccgcgtg gcgtcatcgt gctctcgttt atacttggca cgatattact tagcgtttat
     8161 cggatagttg tttataaact atacttaaga gtcagtcgtg ataagaaagt ccttatcgta
     8221 ggtttggaga aagatgtcgc accagctatc caaaactttc aatctaagaa aaacaacaaa
     8281 cataaagttg aagcagtagt gatcgacaag tattacgaaa acacaaaaaa attgattgat
     8341 gatatcgata ttgtctactt ggcttctaaa atcccagaag acgaaaaaat caatatttat
     8401 caattagtaa ctaaaaaaga gaagaagcta tttttaaata caacttttga aaatttaacg
     8461 atgatcaatc cgaacatcat gaatttcgaa gatgaaagta tcattgaagc ttccggtttc
     8521 aaaattcagc cggaatatga attattcaaa cgtctttttg atatcatcgt ttcgcttatt
     8581 ttactgattc ttgcttcacc ttttatgcta atcacagcga ttttggtaaa aacaacttca
     8641 cctggaccaa ttatttataa acaagtacgt attacgaaaa atcaaaagga attttcaatc
     8701 tataaatttc gttccatgag tgtaacagct gaagcaaaat caggaccggt cttggcaaag
     8761 agcaatgatg cacgtgtgac accagtaggc aaatttatcc gtgccgtacg ttttgacgaa
     8821 ttacctcaaa tctttaatgt attgaaaggc gatatgtcga tcgtcggacc acgtccagaa
     8881 agaccatttt tcgttgatca gttcaatgaa gaaaatcctt attattattt aagacacaat
     8941 gtacgtgcag ggattaccgg atatgcacaa gtatacggaa aatatgtatc agattataat
     9001 agtaaactac gttttgattt gttgtatatc aaaaagtatt ccttactatt agatttgaag
     9061 attttacttc aaacaatcaa aatcttattt gataagatgt cctcacaagg actagatgaa
     9121 gatgaaaata tccgttcgtt agcagaaatc gacttttcac aagagaaaat ttatcgctag
     9181 atgggaaaaa ttttgagcaa agaagtagga gagaacattg gaaaataaaa atataagtat
     9241 gctgctttct ttatatgata aagaaaaacc agagtattta aaggaagcat taactagtat
     9301 ttttgagcaa acagtaatgc caaaagaaat tgtattagtt tatgacggcc ctataaatga
     9361 aaaacttcaa gtagttgtca cttatttcca acaaaaagat cctcacttgt ttacagttgt
     9421 aaaattagaa aaaaatcaag gattggggat tgctttagca attggattag aacatacgaa
     9481 aaatcgctta gtagccagaa tggatacaga tgatatcatg gaaccccaac gattagaaaa
     9541 acaattagag atcttccaaa aagatccaga aatagcgatt gttgggagta atattgagga
     9601 atttactggc acgcttagca atgttatcgg aagaaggatt gtacctgaat ataatgatga
     9661 aatccgtgtg ttttcgaaaa gaagaaatcc ctttaatcat atgacagtca tgtttgataa
     9721 aaatgctatt ttagaagtgg gaaactatcg cccattaatt ggatttgaag attattattt
     9781 gtgggtaaga ctgttgaagg cgggatataa agggtataat atccaagaga ttctagtcca
     9841 tgctagagca ggtgctgaca tgtatgctag acgtggagga agtaaatatc ttttaccagg
     9901 aattaaaggc cgatatcgcg tatggaaaga tggtctagga tcactaaaag attttctgat
     9961 agttatttgc ggacatcttg taattagttt attaccgaat aaaattaggg gaaaagtata
    10021 tgaatcaaaa cttagaaaaa caaactaaac tttctataat catacctttt tacaatgcaa
    10081 aaaatacttt aaaaagagct gtagacagcg tcttaacgca aggttatccc aatattgaaa
    10141 tcttgttaat tgatgatgga tctacagatg gtagtagtga cattggtgac gaaattgcta
    10201 atctagagag taaagtagca tgttatcact tggaaaacgc tggtccatca gttgctagga
    10261 attgtgggat aaaagaagca actggaaatt tggtaggatt tttagatagt gacgattatt
    10321 ttttacctga ttgttttaat aatgttttga aagactacca taggaattac cccgatatca
    10381 ttgcttttgg attaagtaaa ggaaaaaata tagaaaatgc aaatttattt gttcccgaaa
    10441 agaagattgg ttgttcaagt gaagaagcaa ttgagcaaat gtttagaagt aaggcagtgg
    10501 atttttacgt atggaataaa ttttttaaaa gggaattatt caatcatata gtttttccag
    10561 aaaataaatt atatgaggat atggt
//
LOCUS       DAJSMK010000082        10537 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.085, whole genome shotgun sequence.
ACCESSION   DAJSMK010000082 DAJSMK010000000
VERSION     DAJSMK010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10537
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.085"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(43..681)
                     /gene="plsY"
                     /locus_tag="ON488_002113"
     CDS             complement(43..681)
                     /gene="plsY"
                     /locus_tag="ON488_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HCR3232295.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            808..1242
                     /locus_tag="ON488_002114"
     CDS             808..1242
                     /locus_tag="ON488_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HCR3232296.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1408..3453
                     /gene="parE"
                     /locus_tag="ON488_002115"
     CDS             1408..3453
                     /gene="parE"
                     /locus_tag="ON488_002115"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HCR3232297.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3465..5915
                     /gene="parC"
                     /locus_tag="ON488_002116"
     CDS             3465..5915
                     /gene="parC"
                     /locus_tag="ON488_002116"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HCR3232298.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6192..8423
                     /gene="pflB"
                     /locus_tag="ON488_002117"
     CDS             6192..8423
                     /gene="pflB"
                     /locus_tag="ON488_002117"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HCR3232299.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8667..9428
                     /gene="pflA"
                     /locus_tag="ON488_002118"
     CDS             8667..9428
                     /gene="pflA"
                     /locus_tag="ON488_002118"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HCR3232300.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9513..10439
                     /locus_tag="ON488_002119"
     CDS             9513..10439
                     /locus_tag="ON488_002119"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HCR3232301.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
BASE COUNT         3735 a         1823 c         2262 g         2717 t
ORIGIN      
        1 atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt ttttcttgct
       61 gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct tgatattgtc
      121 tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca gtaaccaatt
      181 gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata aagtgatcaa
      241 tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac taacgataaa
      301 gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc ctgcacttgt
      361 cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc caagaatggc
      421 gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt
      481 agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg ttttgcctaa
      541 tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga tatctttttt
      601 gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat atgctaaaat
      661 aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat cctttatttt
      721 agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata atagatggaa
      781 taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt
      841 ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa
      901 cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat cataccagta
      961 aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa tttgacagaa
     1021 atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt acctgaaata
     1081 gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg gattgaaaac
     1141 aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat ggatcgttgt
     1201 attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga
     1261 gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa ttgatttctc
     1321 gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc ggttttgccg
     1381 caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga atacaatgac
     1441 tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg gatgtacatt
     1501 ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga taatgcagtt
     1561 gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga agacaatagt
     1621 ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc cggaatacca
     1681 acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca aggagggtac
     1741 aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg
     1801 ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa aaacggcggt
     1861 aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc
     1921 cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga aattttagcc
     1981 gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct ttctgatctt
     2041 cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa agaatttgtt
     2101 gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc aggagaaaaa
     2161 gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga aaatgtttta
     2221 tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg tatgaaagcg
     2281 gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa agaacgggac
     2341 aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc tatccgtgta
     2401 cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac gccagttgct
     2461 cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca ggaaaatagc
     2521 gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag agaagcagca
     2581 cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga atctcttctt
     2641 tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt gtatttagtc
     2701 gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt ccaagcaatt
     2761 ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa
     2821 aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc tgagttttct
     2881 atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac agacggcgcc
     2941 catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct gattgaagct
     3001 gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca aggaaagaag
     3061 caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa aaaagtcggc
     3121 aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga acaattgtgg
     3181 gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg
     3241 caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg aagaaaatgg
     3301 atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga taaaaaagag
     3361 gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg agcagataaa
     3421 aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa aatcgacaag
     3481 aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt tattccaaat
     3541 atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc
     3601 ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc cgtaaatcag
     3661 caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgaccgc agtatttatg
     3721 aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc gaaatgcacg
     3781 ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact gaagccagat
     3841 tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc gatctcgtgt
     3901 ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac ccaaaccttc
     3961 tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg actcataact
     4021 tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg agccttgaaa
     4081 aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg caaggaaaag
     4141 atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa
     4201 agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc ccatatgaag
     4261 taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag aaaatcgatg
     4321 gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc gtcgaattga
     4381 aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact gagctacaga
     4441 tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa gttggactga
     4501 aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat
     4561 tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg aaagctttat
     4621 cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa
     4681 agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt gtcacattgc
     4741 aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc gaaagcttga
     4801 ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt ttctctgtta
     4861 tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg
     4921 aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa gaagacgtaa
     4981 ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct tatagtgctt
     5041 ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca ggtgaattga
     5101 gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc
     5161 atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa acaatctcca
     5221 atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt caagcagaga
     5281 aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg acagagttcg
     5341 aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag gcggaagaag
     5401 atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt ttcttagtaa
     5461 cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt ggagcaaagg
     5521 cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac gggctgcttg
     5581 tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct gttaaacgca
     5641 tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg
     5701 agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca aaagaaataa
     5761 ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc cctataggtg
     5821 atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag
     5881 ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga
     5941 cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata aatccttata
     6001 cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat
     6061 ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa
     6121 agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg
     6181 aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag
     6241 acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg
     6301 aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc
     6361 aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac
     6421 acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac
     6481 ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa
     6541 gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac
     6601 ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa
     6661 tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg
     6721 tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg
     6781 gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc
     6841 gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag
     6901 ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat
     6961 cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc
     7021 aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact
     7081 tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct
     7141 caggattccc tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat
     7201 tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag
     7261 aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga acatatgcta
     7321 gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac
     7381 aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag
     7441 acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg
     7501 gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag
     7561 aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag
     7621 aactatatgt caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag
     7681 cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg
     7741 ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc
     7801 gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa
     7861 atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa
     7921 tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt
     7981 caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac
     8041 cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc
     8101 tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa
     8161 caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg
     8221 tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg
     8281 atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat
     8341 ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga
     8401 gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa
     8461 aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt tgaaagaaac
     8521 gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg
     8581 caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg
     8641 aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta
     8701 tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat
     8761 gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag
     8821 aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata
     8881 aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac
     8941 tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt
     9001 ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac
     9061 tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca
     9121 atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc
     9181 gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact
     9241 ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa
     9301 aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa
     9361 aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa
     9421 cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat
     9481 taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc
     9541 aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat
     9601 taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat
     9661 tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag
     9721 atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa
     9781 atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt
     9841 actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa
     9901 accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata
     9961 cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg
    10021 cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa
    10081 atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg
    10141 gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc
    10201 gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt
    10261 tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag
    10321 gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta
    10381 aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat
    10441 caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat
    10501 agaacatact aaaggccgaa gaaatggagg agaataa
//
LOCUS       DAJSMK010000083        10498 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.086, whole genome shotgun sequence.
ACCESSION   DAJSMK010000083 DAJSMK010000000
VERSION     DAJSMK010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.086"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            57..938
                     /locus_tag="ON488_002120"
     CDS             57..938
                     /locus_tag="ON488_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232302.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            951..2561
                     /locus_tag="ON488_002121"
     CDS             951..2561
                     /locus_tag="ON488_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HCR3232303.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2638..3297)
                     /locus_tag="ON488_002122"
     CDS             complement(2638..3297)
                     /locus_tag="ON488_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCR3232304.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3580..4245)
                     /locus_tag="ON488_002123"
     CDS             complement(3580..4245)
                     /locus_tag="ON488_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HCR3232305.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4392..4997)
                     /gene="dhaL"
                     /locus_tag="ON488_002124"
     CDS             complement(4392..4997)
                     /gene="dhaL"
                     /locus_tag="ON488_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HCR3232306.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(5025..6035)
                     /gene="dhaK"
                     /locus_tag="ON488_002125"
     CDS             complement(5025..6035)
                     /gene="dhaK"
                     /locus_tag="ON488_002125"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HCR3232307.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(6010..6456)
                     /gene="dhaM"
                     /locus_tag="ON488_002126"
     CDS             complement(6010..6456)
                     /gene="dhaM"
                     /locus_tag="ON488_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HCR3232308.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            complement(6495..7454)
                     /locus_tag="ON488_002127"
     CDS             complement(6495..7454)
                     /locus_tag="ON488_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCR3232309.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            7624..7944
                     /locus_tag="ON488_002128"
     CDS             7624..7944
                     /locus_tag="ON488_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HCR3232310.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(8056..8925)
                     /locus_tag="ON488_002129"
     CDS             complement(8056..8925)
                     /locus_tag="ON488_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCR3232311.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(9021..10325)
                     /locus_tag="ON488_002130"
     CDS             complement(9021..10325)
                     /locus_tag="ON488_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HCR3232312.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEDTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(10322..10483)
                     /locus_tag="ON488_002131"
     CDS             complement(10322..10483)
                     /locus_tag="ON488_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232313.1"
                     /translation="MKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
BASE COUNT         2807 a         2182 c         1971 g         3538 t
ORIGIN      
        1 attaaactat ttaatcttgt ttagtatata tttttagaaa aaggagtggg gtttttatgg
       61 cagaaatcgt caaagtcaca catttgaaaa agagctttgg tcgtttcgaa gctttaaaag
      121 atgtctcttt caccgtacat tcaggtgaag tcgttggatt tatcggacca aatggttctg
      181 gaaaatccac gacgattcgg acacttttag ggattataaa aaaagacggc ggaacggcaa
      241 cgatttttgg gcaagatgta tgggaagata gtttatctat ccatgaacgt ctttcttatg
      301 ttccaggcga tatctctttg tggggaaatt tgactggagg agcgatcatc gatctcttca
      361 tgaagcttca tggaaaaggg agtgctcaaa aaaaagatga actgattcaa cgtttctctc
      421 ttgatcctaa gaaaaaagca aaaaactatt caaaaggaaa tcgccaaaaa gtgggcttga
      481 ttgctgcttt ggctgttgat tcggatctct atttatttga tgagcctact tctggtttag
      541 atcctttgat ggaaacgatt ttccaagaag aagttgaaaa attgaaagaa cagggcaaat
      601 ccatcctact ttcttctcat attctcagtg aagtcgagcg actagcggat aaagtcgtga
      661 tcatacgcga aggaacactc gatgaagaag gaacactcga tgaattgcgt catttgactc
      721 gttcgaccat cactatagaa acagaagcag agaatagtca cttagcacaa ttgaacggtg
      781 tccatgactt tgtgcaaaaa ggtcacctcg ctcaatttgc tgctgataac gaagctttcg
      841 atgtgatttt agctgaagcg tccaaattag gtgtgaaaaa atttgaatct attccaccga
      901 ctcttgagga tttattcatg agacattatg aaggatgagg aggaagcgaa atgactgata
      961 aattttcacg ctggtccacc cttttttctc aaaaccttag ccgtgactgg aaaaagatcc
     1021 tgatatggct agtcggtgtc actgcttttt ctggtggttt tgtccctgcg tttgaagaat
     1081 tgacttccgg acaaggatta gctggattat acgaaacctt gcaaaacccg gcaatgattg
     1141 caatggtcgg accaactcca gcttcgaatg ctgctgagta tactttagga gcgatgtatg
     1201 caaatgaaat gttgcttttt tgcagtttgt ttgctgctgt gatctctgtt ttacacgtgg
     1261 tgagccaaac gagaaaaaaa gaagaacttg gtctgattga acttattcgt tcctttcgag
     1321 tcggacgtca agcaaactct ttagctgtca tcgctgaaag tattctgatc aatttgcttt
     1381 tagcaatatc gatcagctgt acgatgattt ttttccaagc ggattcgatc actgcagaag
     1441 gtgcttggct ttttgggcta tctgtaggta gtatggggat tttggggagt gccgttgcac
     1501 tgtttgctgc acaactgatg ccaagttcag ccagttcgaa tggtctgtct ttagcgtttt
     1561 taggtggact ttaccttcta cgagcaataa cagatgtagc tgattcctcc ctttcgatgt
     1621 ggaatccttt aggctggtct tatttgacct atccatttac aactaacaac tggattcctt
     1681 tgctttattt gtttttgttc agtctaatct tgataatcag ttcatttgtt ttagaggaac
     1741 atcgagattt gaacaccggc tatatccccg aacgtgaagg aaaaccgtat gctaaacgtt
     1801 ctcttttatc cttgcgtggt ttattattct atctaaataa agggatgaca atcagttggc
     1861 ttatcacttt tggtttgatg ggggcggcat acggctctat ctacgggaat atgcaacagt
     1921 ttttagaaag taacgactta atgaaacaga tgtttatcca atctggcgtc tcaattgaaa
     1981 aaaactttac aagcacgatc atggtcgtct tgatttgtct agctgctatt ttaccaattg
     2041 ctagcatcaa tcgtttattt acagaagaaa cccacggacg tatgaatcag ctgttcgcaa
     2101 caaaaatttc taggaaccaa ctttattgga ccaatatgtt actagctatt ctatttgcta
     2161 tattggcaat cctgattagt tctggtgcac tagggctttc tgctttggct tcgatgaagg
     2221 atgcgaaaga catggatcta ttgatgtttc ttaaagccgg gttcaatttc ctgcctgccg
     2281 ttttagtgtt tatcggaatt agtggctttc tattcggatg gcttcctcga atcggtaaac
     2341 ttgcttatat ctacttagct tactcctttg cactcaatta ctttggcgga attttggatt
     2401 taccagaatg gttttccaaa acagctgtcc ctagctgggt tccacggatg ccaaacgatt
     2461 cttttgatct ttccgtgttc cttacgttat catgtatcag ccttgcactg ttcgtccttg
     2521 gttctattgg ttataggcga agagacttac tagaaggata ataaaaaagc atgtacaatt
     2581 tcatgctagc ctccaaatct gggtcaaaaa tccaacattt ggaggtcatt tttttattta
     2641 caagtcttct aactgctctt tatcaatgat ccagacttct cgattctttc tttttacata
     2701 accattctcc tctaataatt taaattttct agataaagtt tcgggggtcg taccgataaa
     2761 tgcagcaagt tctttcattt tcattggcag gaaaaagtga tccttccctg tcgctttagc
     2821 taagtcaagc agatagacag cgactcgttc ttctactttt tccatcatca aaaaagttgt
     2881 ctgctgctgt acttttgtta atttctcaac gttgattgct aaaagtttca gactaagggc
     2941 gggataatgc agtaagagtt ccgagaaatc tttttgtctc aatatgcaaa tttccgtttt
     3001 ttctagtgct tcgccaaata aagactcatt tggaacgcct agcaactggc tctctccctc
     3061 atatccgccc ggctctatta ctcgtaaaag ctgttccttt ccgctagcag ataattgata
     3121 cactttcata ctgccggagg ccacgatcac taattgaggt tctccattcg gcgcaagaat
     3181 ctgttctcct ttttccacat agtgatgttt gacaagtgcg tgtacttttt cttgatcttg
     3241 ctgtactaag tgattgaaca aaggaacaaa tgaaacacat aaatgatcat gactcataat
     3301 ctctcctcct tctaaacagc tatttctaat aaagaaacat aacttccctt attccaactg
     3361 ataattttct tttatcatag cataaacgtc aagcgaacca gataccagca aatagagtgg
     3421 atttcttttt gtcccttgct ttattttcct tcttttgaga ccttaagtaa ttgattccta
     3481 tcaatttttt aaatatttac tttttgaata atcaaaaaca aaccttcact cgcaagccga
     3541 gagtaaggtt tgtttttcgc attgcttatt tcgtgttgtc tattgaaatt tttccgcacc
     3601 tagcttttga tatagtggtg ctagttcttg taaggtttca gcggttattt gctcaacgtg
     3661 ttcgatttct tgcggataga agaatagttt acccatttga aaggttcggt ctctcatcgc
     3721 ttttttcaac tcttcttgtt tctttgtatc ggacaaatag tcagacaaag ctaagtggtc
     3781 gtcaagttca tgttctggtt gcggccatat gtaataatcc ttgatatcga ctgttttgct
     3841 ccactctttc agtatcgcaa gcaactggtt atacgctgca atgctaccat atcgttcttc
     3901 gcttttataa tgttggtaca tcaaatagat ttggtattgt ttttgattca acaaaactgc
     3961 tagacaggca ttctcgtctt gacgagattc gcttcggtac gcgctccaaa aatgactgcg
     4021 taaattccag ccattcgtcc agctttcgat tttaggtttg ctcatgccgt acatatcagg
     4081 caaaagtgca gctgtctgga gctgaatctc tttccatttt tgccagtgtt ctttatattc
     4141 tttcttgatt tgttcaatct tatctgttgg atggctctct ttgagctgtt tgaatgcgta
     4201 gattggtcga tcaaacaact gataatctga ttttccaagt tccattgttt cgcctctttc
     4261 cgttatcttt tgtattctac ctgaattttg cgatatggac aaatagaggt tgtgaaaaag
     4321 ctgttctgca tcaagtcata agaacagcca aacaaaaaac tgcgatgagc atcaccgcag
     4381 ttttattgaa cttaaggttg attgatcaca tctaaaagcg ttgaaaataa aatggcacta
     4441 gaagcagctc ctgggtcgat atgtccgatt gcacgctctc ctagatagga agctcgtcct
     4501 tttttagcta ccaagacttt ggtgtgttct tttgcctggt caatgatttc ttttgttaaa
     4561 ttccctgcct tcaatgcctc tgtgactggc agccaaacat ctaacatcgt tttatcgtca
     4621 gcttctgcct ttcctcggct ttgaataccc gctgttccct gctcgatcac ttcgcctaat
     4681 ttttcttgag aatcaataga atcgacctct tttgtcgctt tcatcatgtt catgaatgca
     4741 gatccgtata acggaccaga agccccaccg actttcgata tcatcgccat agagaatact
     4801 ttgaatgtat cgctgattgt ttcaggatga tcggcttgaa aagcttcttc ataagctgaa
     4861 acccctcttc ccatgttatt tccatggtct ccatcgccaa tcggggtatc tagatcactg
     4921 agatattgtt tgttctgatt gattgcctct gcaaattgcg tgagccattc ttggatttct
     4981 tgaacggtta gtttcatatt atcacccttt tatcttgaga ttttttacca tgaaatcgtc
     5041 tgtacattgc tttctaaaga atctttccat tgtgtctccg tcaagtcgat cagtgttaga
     5101 gaaagacctt gcatatctag tgaggtcata aaattaccga cttttcggaa aactacattg
     5161 acgcctcttt cttccaacag agctaaaaca tcattcatga acacgaactg ttccatcaaa
     5221 ggcgtcccgc ccattccgtt gactagtaca cctgcttctt ttggtaaatt cgagtaatca
     5281 tctaaaatct tagtaacaag ttcctttgcc agtactttag aaggctgcat cttttctcga
     5341 cgatagcctg gctcaccgtg gataccaaca ccatactcga tctcatcttc tcctagttcg
     5401 aatcctggtt tccctacttc tggtacagtt gctgctcgaa gcgctagacc gatcgtctta
     5461 gttgcctgta cgaccttttc tcccagttct ttcaactcag ctagggaagc accgtttctt
     5521 gctgcatcgc ccacgatttt gtgtacaagg acagtacctg caactccgcg ttttccagca
     5581 gtatacgtac tattttcaac ggcgatatca tcatctacga tcacactttc tacttcaata
     5641 tcgtccatag cagctaattc ctttgccata tcgaagttca atgcatcccc tgtataattc
     5701 ttaacgatca gcaaaactcc ttttccacta tcggcttcct taatagccgt ctgaatctga
     5761 tctggagttg gagaagtaaa cacatcacca agcaccgctg cacttaacat cccttcccct
     5821 acaaacccgg catgggatgg ttcatgtccg cttcctccac cagaaaccaa accaacttgt
     5881 tccgctttct gattcttggc tacaacacgg gaagattcta cacgatgaac aagttctgga
     5941 tagcttttta ctaatccttc cagcatttct tcgacaatat tgcttggatc attcatgatt
     6001 tttttcaatt tattcccatc ctttctttcc ggcattttgt gcttctgtta agatttgctg
     6061 agtatcatct gttataccgg cagtgatggc tgctgcaaaa gctccttcca ctaaaggcgc
     6121 atccaccaga tgataacgtt gctgctgctc ttcttccaac atgtcttttg ccagttccga
     6181 gttcaatacc gcgctaccga tatccgcaaa aacaaaataa ctagctgcat cgcttgattc
     6241 attgactgct tctacgattt tcatcgggtc tgatccgatc tcgccattta ttccgccgag
     6301 agaaaaaatt tgcacctctt cggatttttg catctgctca atcatttctt taataccatc
     6361 tgttactttt tgactatgag aaataagcaa aatacttttt ttcacaagaa tcttcctttc
     6421 ttttacatag ttgctaacga ttggtttcgc tttcattaat gaacaattca agtatataat
     6481 aaatttttcg tttgtcaaat taagctagac aaatcatctt tacctacgta actcaaaaat
     6541 acttccaatg gtgtgcgata gtgtaatgat tttctaggaa tatgatttcg ttttgatgcc
     6601 accgattgga taaaggtttc ggatacctta ttaaaatcca tagctttata taagccatct
     6661 ttacgtaata agccattcga atgttcattt agtcctcgtt gagaaggtgt tcctggatca
     6721 gcgaaataaa tcgaaatatc attggtatta ctaatctttt tccaattcga gaactctttt
     6781 ccacaatcaa atgtgatgga tttaaacaag tgtttcggta cagattgaaa ccattgattc
     6841 agtctattct caatatctat agcttgccta ccagcgggtt tcaaggtgat gatcacttta
     6901 gataatcgct caactaacgt gatcaccgca cttttatgtt ttccaccgac aatggtgtca
     6961 ccttctaggt gaccaaactc atgattgaac tgtatataat cagttgttct atcctgaatc
     7021 gaacggcgaa aagcttgttt tcctcttttt tctttatgtc cgtttggttt tcttttccct
     7081 ttcattggta aatcgtgagg gtcaaaggtt ttatctttaa acatccgata tagtgtacgt
     7141 accgaacaag caataggaaa ctctgctcga ccaataagga catctggagt ccacccttga
     7201 gccacctttt tttgaatgta ttcttgttgc ccatctggta acacaatcgg acgtcttccg
     7261 cagttacgtt tgtttttctt atattgttca tagtagctta ttgcgcttcc accagattta
     7321 agaaaacgat agacattata aatggtttgt cgagaacgtt gtaccagatg ggctactttt
     7381 gaaacagagt gtgattgatt gaaataagct tctatcatta cgagttcagt tggtgtaaga
     7441 tgggtatagg tcatttgtac tcactcctta taattctttc gacggaacta ttttgagtgt
     7501 agcacaaatg acttttttag ttgtctagct taattttaca atcggcgatt tctaattttg
     7561 ggaaaatatg tgtagtgctt cttgaagttt gttatacttt aattaaaaga gaggagtgat
     7621 cgaatgatta caacaacaac gaacagtgta gagggaaaag ccgtagtagc ttataaaggg
     7681 atcgtttttg gtgaggtcat tactgggatc catgcattta aagacttgga ggcggggttg
     7741 cgaaatatct ttggcggccg ctcaaaaagc tatgaaaacg aactaatggg tgcaagagaa
     7801 gaagcacttg ccgaaatggc cgaacgtgca aaagcattag gagctgatgc gatcattggc
     7861 gtaaaaatgg actatgaagt attaggcagc gacaatggca tgctgatggt cacatgtagt
     7921 ggaacagctg tctccacgag ataagtaggg gacatctgtt ttaataacta aagagagatg
     7981 ggacatgtag tggcactcaa gaattagatt tttcagtcta acttcgaggt actctacctt
     8041 cccatcctct cttttttatt tctttttgcg gatgattccg taagctgctg cgactaacac
     8101 acccgcccct gctaaggaat aactgacaga agctgttttt tcatttgttt ttggcaaagt
     8161 ctgacttgtt gatttggatg gctctgtcgt ttgctgaact gtttctgtcg tgcttccaga
     8221 ggtcactgat ttttctcctg ccgaatgcaa aatatctttt attcgttgga aactagctgc
     8281 taagtcagct ttttttgctt caaaatcatt agcaactgtt tgtgcttcgc tgatctttcc
     8341 gtggattgct tgactggccg ctgtgatatc cgcttgagtt tgacttagct ttccagaagc
     8401 tgtttgagca acctgattta attgctgatt gaattctttt gcttgttgga tcttcccgtc
     8461 aagatctgtt tggacagctt ccgcttttgc tttcgcttcg gcaagctttt tctcaagttg
     8521 tgcacggtca tttcccactt tatttttaag atcagctaaa tcttgatcga ttgctgcttg
     8581 gtcttctttc aatttgtttt ttgcagcttc taatgcttct tcgagttctt ttcttttatt
     8641 ttccaagtct tgcaaatgat cgatttggtc agaagaggta gaactattta ttgatgtatc
     8701 ttctgaagat gaaatcgttt ctcctgaatt atctgtcggt acattggaag tcatttctgt
     8761 ttccgaggca ccgttttcag caccagaaga gcttatggtt gttgaaggtt ctgtttgagc
     8821 aggttcagaa gtttccgcaa aagctgtctg tcccaataag aaaatactgg aaacagcaat
     8881 tggccagatt aacggcttca ttcttttttt catcactttt cccatcctta ctacttttta
     8941 actaatttct tattataagc aaaaatgttt ggaagaacca taaacacaac aggctgtttg
     9001 tctaaaaaac ggtgcatctt ttattttttt gtacgttccg ggcttttcca tgtcccgctt
     9061 ccataaccta aaatcgtttt gactgctgga atgaaagtcg tcacgatcgt tatcgcgttc
     9121 actatccaga acaaaagcat atatagtggt gcgaaaagaa ggtatttcaa ttttcttcgt
     9181 cgatcatcta caatcagcga agctagcaac tggaaaaatc ctgcgaccat ttcaaagcag
     9241 atgaacacaa aactgaatgt aaaagtaata taaatctgtt cgtagtttcc ttgatataca
     9301 taatgcccga ttaatccagc aaaaagaact acggaaatac aaaagaatat tgaccagaca
     9361 atactcaatg tttgatcaat gaagatgatc gttcttccaa tatgtttaaa aggatggagc
     9421 atcacttttt tgaaattcgt cagccagact tctgttccac cttttgccca acgttttctg
     9481 tgtcgatata gcatcttcaa cgtcacaggt acttccatga aaaagataat ctcaggagca
     9541 aaaacagata accagtcatt taactgatga tcccaagcaa tactgatgtc ttctgtcgct
     9601 cgatcttgtc tgaatccgcc cacatcgatc aaggcttctt ttcgatacat cgtatttgct
     9661 ccactgtacg cataaagacc accgaaaaca gctgactgtg ttcgtttaat gatgcccacg
     9721 atacttgaga attcaaccgt ttgagatttt gcaatcaatt tggtacgatt ttggacatcc
     9781 atatttgcag tgaccgcagc aatatgtctt gcaccagggc gaatgaaata attcacatac
     9841 ctaatcagtg catctggctc cggtaccgtg tctgcatcat tgcttaaaat caatttccct
     9901 tttgcaaagg caagtccgat attaaacgcg tgggcttttc ctttattttt ttcgatccga
     9961 accacacgaa gattagcgta ttttttcatc agtctagcta atatttctgg tgtttggtcc
    10021 gttgaaccat cgtctgtcac taatacctca tagttgtgat aattcaattt cgtcatcaaa
    10081 tactcgattg tatcttcgat cacaatttct tcattatggg ctggcaccat gatcgtgatg
    10141 aacggttcga cactcaaggg aacatctacc cattcttttt gcttatgttt gtataaaaac
    10201 acataacacc agacaccaat aaaccataca aatccgccta aaatcggata agaaacgaga
    10261 aaaaaataca taatagacaa acaagtatct aagaataaat tacctgtatg ggtgattgag
    10321 atcatttcag ttccacccca ttttctttat acaaatctgc aatgaatgtc gtatctagat
    10381 ttttctcttc ggagacagaa taaaaacgga ccgtttctct ctcttctttt gttccaaaac
    10441 gttccgtata cacttcttca agtaattctt gtcttttttt caatttttca tcttcata
//
LOCUS       DAJSMK010000084        10085 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.087, whole genome shotgun sequence.
ACCESSION   DAJSMK010000084 DAJSMK010000000
VERSION     DAJSMK010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.087"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(47..367)
                     /locus_tag="ON488_002132"
     CDS             complement(47..367)
                     /locus_tag="ON488_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HCR3232314.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(515..2749)
                     /locus_tag="ON488_002133"
     CDS             complement(515..2749)
                     /locus_tag="ON488_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HCR3232315.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3228..3494
                     /locus_tag="ON488_002134"
     CDS             3228..3494
                     /locus_tag="ON488_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HCR3232316.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3494..5221
                     /gene="ptsP"
                     /locus_tag="ON488_002135"
     CDS             3494..5221
                     /gene="ptsP"
                     /locus_tag="ON488_002135"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HCR3232317.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            5385..6431
                     /locus_tag="ON488_002136"
     CDS             5385..6431
                     /locus_tag="ON488_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCR3232318.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            6448..7671
                     /locus_tag="ON488_002137"
     CDS             6448..7671
                     /locus_tag="ON488_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HCR3232319.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            7760..8647
                     /locus_tag="ON488_002138"
     CDS             7760..8647
                     /locus_tag="ON488_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HCR3232320.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            8733..8963
                     /locus_tag="ON488_002139"
     CDS             8733..8963
                     /locus_tag="ON488_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HCR3232321.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(9020..9985)
                     /locus_tag="ON488_002140"
     CDS             complement(9020..9985)
                     /locus_tag="ON488_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HCR3232322.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
BASE COUNT         3208 a         1786 c         2036 g         3055 t
ORIGIN      
        1 ctttactttt gtcccacgct ctttaattat tatgttcaaa atttgtttac acggctaatg
       61 tagcgcctaa ttcatgtttt ggaatcgaga tttcaacaag gcctgccaat tcgattactt
      121 tgatttcatc ctcgtggtaa acggcgtctt tgattttatc taagaaataa tttttagcat
      181 cttcgatttc tttcggctgg attttacgtt tgtcattgat cagcagaatt tcattatgtt
      241 caggggcttc agtgtagaca atagtggtat ttccggctgt gtagaccttg actagatggg
      301 catcagtgtt ttcaagctgg tttaatacaa gacgggaatg gctgtttgtt acatttacca
      361 atttcatggc gctcacctct tttatgtatt tttaattgct tgtttctctt attataattt
      421 cttttttata aaatgaacag tattttgact tttctgaaaa aagaatgaga cggcatttct
      481 caaagaaata ccgtctcacg ctataaaact ggatttattc agccgtttct tcggctgatt
      541 ctttagccaa acgttctggt ttagaagtaa cgatgatttt tccatcttta tccagttttg
      601 ctttcaactc atggatagaa gggtgatcaa gataaaattc agcgatacca tcttcgattt
      661 gttcttggat cgtgcgtcga agaggacgag cacccataga tggatcatag cctaagtcaa
      721 ctaatttttc tttgacattc gtaggaactt cgatgtgaag ttgctgtgct gccagcattt
      781 ggttgacatc gtctagcatt agtgtgacga ttgtcatcaa gttttctttt gataatgcac
      841 tgaattcgat gatcccgtca aaacggttca gaaattctgg tgtaaagtag ttgtttaatt
      901 ggttcaatac agaacgagta acaccttcgc gtgccgcacc aaaaccaacg tttgcttcta
      961 ctttaccagt tccggcatta cttgtcataa tgatgatcgt atctttaaag ctgaccgttc
     1021 ttccttgtgc atctgtcaat cgaccatcat ctaagatttg caagaacata tgcaaaacat
     1081 ctggatgagc tttttctact tcatctaaca agacaagact gtaaggattt ctccgtactt
     1141 tttctgttaa ttgaccagct tcttcgtatc cgacataacc tggaggagaa ccaatcaatt
     1201 tagagacact atgtttttcc atatattcag acatatcgaa acgaatcatt gaatcttgtg
     1261 aaccgaatag ttcgtaggca agttgtttcg caagctctgt tttacctaca ccagttggtc
     1321 caacaaataa gaaggagccg attggacgat tctgtttgtt taatccaaca cggtttcggc
     1381 gaatcgcttt cgctactcga tctacagcgt tatcttgtcc gatgacatga gctttcaagt
     1441 catctgctaa gtttttcagt tgtgtctgtt ctttttcttt taattcaccc actggaatac
     1501 ctgtccgttg ttcaacgatt ttttccatat ctttttcggt aatcacaggt gtttcctctt
     1561 cagtgagctg acgttctttc attttttgaa gtttattgat ctgatcgcga taataagctg
     1621 ctttttcgaa atcttcttct cgagaagcta aaactttttg ttcttctgct tcttgcagtt
     1681 ttttctcgat tgttttagga tcaacgattt ggatcgtcaa gtttttctta gaacctgttt
     1741 catctagcaa atcgatggct ttatccggca agaagcgatc ttggacgtaa cgattggata
     1801 aagttgcggc tgcttcgatg gcctcatcag tatattttac atgatgatag tcttcataac
     1861 gtttttgcaa acctttcaaa atactgatcg tttcttcgac agttggttca tctacccgta
     1921 caggttgcat acgacgttct aaagcagcgt ctttttcgat gatgcggtac tcatttaagg
     1981 tagtagcacc aaccatttgc aattctcctc gagctaaagc tggttttaaa atattaccag
     2041 catccatatt tccatcacca gcagaaccag caccgactat ttcgtgaact tcatctatga
     2101 ataggatcac attttctgct tgacggatct cttcaatcaa tttttgcata cgttcttcaa
     2161 attgtcctcg tataccagta ccttggacta aagatacgac atctaaacga atgacttctt
     2221 tgtccattaa tttttgcggt acatcaccat ctacgatttt ttgtgctaaa ccttcaacaa
     2281 ctgctgtttt accaacacct ggttctccaa tcaagacagg attgttcttg gttcggcgat
     2341 ttaaaatttc aatgactcgt ttgatttcgt catcgcgtcc gatcacagga tcgatatcac
     2401 cttgtcgtgc ttgttctgtg atattgattc cgtattctcc caataaacct tctgtattgc
     2461 cttgaggtgg ctgaccacca ttgaagttgt tgtttccgcc aaattgtgtt ggtggtgttt
     2521 gctcataatt tccttgctgt tgcatttggc gagacatgga acggaaaaga tcgtccaaac
     2581 tgccaaatcc aaatggatca ttttgggcca tattagtcag acctccattt tgttgatttt
     2641 tgattttttg ataacagctc tgacagtaat cgagttgtgt ccgctgacca ttgacagtgg
     2701 catacaagtg aatcgttgcc tcattcttgc cgcagttttg acaaagcatg aatcattcac
     2761 gtcctttcac aaaaatgggt acatccatat tttacatctc gtttttcatg aggtaaaaga
     2821 ataaccccta gttttttaag agatttatga ggtagaaaag gtgaaatctc tattgaccat
     2881 tcctgacctt tgactcttat tatactaaaa ataaaaaggg aagcaagtaa ttcgtttcat
     2941 atgaaaacaa agagggtcaa aggaaagaat gataaacgtc aggagaagag aaagcgacaa
     3001 gaaaaaggaa ataaacacgt ttgttataaa atgtgaagaa aaggatgaaa aagaatccgg
     3061 aataatttga atacttttat ctgaaattga atgaaaactg ttgtatctaa cgaaaaaaaa
     3121 tgttaatctt tacagatgaa agggtggcat ttgttaggat tctctgaatt actaaaaaag
     3181 aaaaccctca cataaaaaca acactcactt aaaggagacc gattaatatg gaaaagaaag
     3241 aatttcacgt agtagcagaa actgggatcc acgctcgtcc agctacacta ttagtacaaa
     3301 cagcaagcaa atttaactct gatgtaaact tagagtataa aggtaaatca gtaaacttga
     3361 aatcaatcat gggcgttatg tctttaggtg taggtcaagg ttctgatgtt actattactg
     3421 cagaaggtgc tgacgaagct gatgcaatgg cagcaatcgt tgaaacaatg aagaaagaag
     3481 gcttatctga ataatggttg aaatgctaaa agggattgcc gctagtgacg gtgtagccgt
     3541 tgcaaaagct tacctgctag ttcaaccgga tttaacattc agtaaggcaa cagtagaaga
     3601 tactgcggct gaagaagctc gtttggatgc tgcattagct aaatctactg aagaattgca
     3661 gcaaattcgt gaaaaagcag cgcaaagctt aggtgaagca gaagcgcaag tatttgatgc
     3721 ccatttgatg gttctttcag atccagaaat ggtaggtcaa atcaagcaaa atattaaaga
     3781 caacagcgta aatgctgaat cagcgctaaa agaagtaacg gatatgtata tcggtatgtt
     3841 cgaagcaatg gaagataatg cttatatgca agagcgtgct gcagatattc gtgacgttgc
     3901 taaacgtatt ttagcgcact tattaggcgt tactttacca aatccatcaa tgatcaacga
     3961 agaagtggtc gttgttgcac atgacttgac tccaagtgat acagcacaat tagatcgcaa
     4021 ttttgtaaaa gcgtttgtaa cagacattgg tggacgtact tcacattctg ctatcatggc
     4081 acgttcttta gaaattccag caatcgttgg gacaaaagaa attactgcta aagtcaaaga
     4141 aggcgatatt ttggctgtca acgggatcga aggcgatgta atcatcgatc ctacagatga
     4201 acaaaaagct gaatttgaaa aagcaggtgc agattacgca gcacaaaaag cagaatggga
     4261 aaaattaaaa aatgcagaaa ctgtcacagc tgacggcaag cattttgaat tagctgcaaa
     4321 catcggaaca ccaaaagatc tagttggtgt ccataataat ggtggagaag cagttggtct
     4381 gtaccgtact gaattcctgt atatggattc tccagacttc ccaacagaag atgaccaata
     4441 tgaagcttac aaagctgtat tagaaggtat ggaaggaaaa cctgtagttg ttcgtacaat
     4501 ggacatcggt ggagataaag aactaccata tctgcaatta cctcatgaaa tgaatccatt
     4561 cttaggatat cgtgcattgc gtatcagttt atctgaacaa ggcgacgaaa tgttccgtac
     4621 acaaatgcgt gcattgcttc gtgcatctgt tcatggtaat ttacgtatca tgttccctat
     4681 ggtagctaca ctcaaagaat tccgcgcagc aaaagcgatc tttgaagaag aaaaacaaaa
     4741 attgataagt gaaggcaagg aagtatctga tacgatccaa gtcggcatca tgatcgagat
     4801 tccagcagca gcagtcttag cagacaagtt tgcaaaagaa gtagatttct tctctgtagg
     4861 tacgaacgat ttgattcaat acacaatggc agcagaccgt atgaacgaac gcgtttctta
     4921 cttgtaccaa ccatataacc catcaatttt acgtttgatc aaaaatgtaa ttgatgcagc
     4981 acacgctgaa ggaaaatggg caggtatgtg tggagaaatg gctggagatc aaacagctgt
     5041 tccattgcta gtaggtatgg gtctagatga gttctcaatg agtgcgacat ctattcttaa
     5101 aacgcgtagt ttaatgaaac gcttggacac agcgaaaatg gctgaacttg ctgatcgtgc
     5161 attgaaagaa tgcgatacga tggaagaagt cgttgaactt gttcatgaat atgtaaaata
     5221 aacaacgtat caaaagctgg tgtggcttgt aaaagagcta cgccagtttt tttgttcttt
     5281 tttaagaaaa cgtttttgtc agtaagaata gacaaaaata gggcttaagt ttgagtgaca
     5341 gtttgtaggc tatgttatac tatataagtg aagggggacg taaggtgaag gtattattat
     5401 attttgaaag tgaaaagatg cttgcaaaat ctggaatcgg gcgtgcgctt gatcatcaaa
     5461 aacgtgctct gacggaagtc ggtatctctt atacactaga tgaaaaagaa gattatgaca
     5521 tcctgcacat caatacatac ggaatcaata gtcataatat ggtcaataaa gccagaagag
     5581 aaggaaaaaa agttgtctat catgcgcatt ctacagagga agatttccga aattccttta
     5641 tcggatcgaa ccagctttct cctatcgtaa aaaaatatct ggtaggattg taccaaaaag
     5701 cggactatct gatcacgcca acaccttatt caaaacagtt gttggaaagc tatggtatcc
     5761 gtgtgccgat tcaagctatt tccaatggga tcgacttaga gaaatatcac cctgatccaa
     5821 tgaaagaaca aaagttcaga gaatatttca aactgtctcc ggatcaaaaa gtaatcattt
     5881 gtgtcggttt gtttttcgaa cgtaaaggaa tcattgattt cgtagaaatt gctaagaaga
     5941 tgcccgaata cacatttatt tggtttggtc atgttcccat gtactcgatt cctcggaaca
     6001 tccggaaaat tgtaaaagaa gatcatcctg aaaatgtcct gtttcctggt tacattcgtg
     6061 gagagatcat agaaggtgcg tattcaggtg cagatctatt ctttttccct tcttatgaag
     6121 agacagaagg gatcgttgtt ttagaagctt tagcaagcaa acaaaacgta cttgttcgag
     6181 atattccagt gtataatggc tggttagaag atagcaagaa ctgctatatg gggaagacaa
     6241 acgaagaatt tatccgactg atccaacaga ttaccaatca agaactaccg agtacgacac
     6301 aagccggtta tcaaacagca aaagagcgaa gtatcaataa aatcggtgaa gaacttaaaa
     6361 atgtatacga aagtgtactg aatgaaaaag tctctagcaa attaaaaaaa gtaaatcagg
     6421 tcaaggacta gtttggaggc gaaaaacatg aaaatcggct tttttaccga tacctacttt
     6481 ccgcaagtca gcggagttgc tacatcgatc aaaacattaa aacaagaatt agaaagacat
     6541 gggcatgaag tctatatttt tacaacgacc gatcctaatg cggataagtt ggaaaaagat
     6601 gtgattcgaa tgccaagtgt accatttatt tctttcaagg atcgaagagt tgttgttaga
     6661 ggcatgtggt atgcttattt ggttgccaaa gaactagaac tagatcttat tcatacccat
     6721 acagaattcg gagcagggat acttgggaag atggtagcta agaagttgaa aatacctctg
     6781 atccatactt accatacgat gtatgaagac taccttcatt atatcggtaa aggaaaagtg
     6841 atcaggcaat cccatgtaaa atacttgtct agattatttg caaatcatac gacaggtgta
     6901 gtttgtccaa gtgaacgtgt tattgataca ttacgcagct atggtgtaat agcaccgctt
     6961 cgcgtgattc ctactggtat cgacattgaa aaattcaaac gttctgatat cactcagcag
     7021 gatatcagca aattaaggga gtcactaggt cttcaggaaa accatttgat gattctttct
     7081 ttaagcagga tttcttatga gaaaaatatc caagccttga ttaatgggtt tcctcaggtc
     7141 atctccgctt atcctaacgc cagattagtt atcgtaggaa aaggacctta tgtagaagag
     7201 ttagaggaat tgatctcaga actgcagtta gaagaatttg tgcagttcac aggagaagtg
     7261 gacaacaatg atgtagcact ttattataaa gcggcagatt attttgtcag tgcttctact
     7321 tcagaaacac aagggcttac ttatacagaa gcgatggcag ccggaacacc ttgtgtcgtg
     7381 gaaggaaatg cttatttgaa ccgattgttc gatcatcctt cattagggaa aacttttgaa
     7441 accgacgaag actttgcacc agcacttatt gattatattt ccagtgaagt tcctaaagat
     7501 ccaaaagttt tagaagctaa actttatgat atttcatcta cacatttcgg cgaagctatg
     7561 atcgaatttt atcaagacat ggttgtttat catgaagaag agatgcgaag aaaagaagaa
     7621 gaagactcga ttgaacgaat caaaataaaa ttaaattcat ttaaaagata aaattcaaac
     7681 attttttatg aaaaaatcct tgtttctagc gtatactagc atagaagcaa ggatttttga
     7741 tttttaggag gtcgaaaaaa tgaaacttgg ttttatcgga acaggcgtca tgggaagtgc
     7801 tgtcgcacgc catctactag aagcaggaca cgaagtagct gtctataatc ggacaaaagc
     7861 aaaagctgat cctttagtaa cagaaggagc tatctgggca gatacaccaa aagcggtagc
     7921 agaacaaagt aatattctct ttacaatggt aggttacccc aaagatgtag aagaaatcta
     7981 ctatggacag tcggggattt tttctgcaga tatctcagga catattttag ttgatttgac
     8041 tacaagtaca ccaagcctgg cagaaaaaat tgcaaaaaca gcaaaagaaa aaggcgcaga
     8101 tgcgttagat gcaccggtat ccggtggtga cttaggagca aagaatggta cactgacgat
     8161 catggtcggt ggagaagaag ccgtttatga tcaagtactg cctttattca aagaatttgg
     8221 tacgacattt acattgcatg gttctgctgg gaaaggtcag catacaaaaa tggctaatca
     8281 gatcatgatt gcaggtacga tgacaggaat gacggaaatg cttgtctatg cacaaaaaaa
     8341 cggacttgat ttaaagaaag tgattgagac gctttcaggt ggaagtgcag ctaactggtc
     8401 tttaagcaat tattctcctc gtattttaaa agaagattac acacctggtt tttttgtcaa
     8461 acattttatc aaagatttaa agattgcatt agaagaagca gaaaaaatgg atcttgtatt
     8521 gccagcaact acccaagcat tgaaactata tgaagagttg gcagataaag gttttgagaa
     8581 tgacggaacc caagctttga tcaaactttg gtggcctgaa ggaaaaatac cagaaaaaaa
     8641 atcataaaaa acgagttttt ttagagaaaa tcaatgcaag taggctatgc ttttgataca
     8701 atataacaga aataagaaaa ggaggacctc cgatgacaca ttcacaatta gtcgcaatca
     8761 taaaacgact ggaggctatg gtcgagtcag cagataatga actgcaagtt cgccgttttg
     8821 aaaaagaagg cgtagagaag tgtacagtaa cttatgataa agcgaccgat acatttgaat
     8881 taactgaaac agatactcat cagcaatacg aatttgataa tatcgatatc gtagcgatgg
     8941 aaatctatga cttaatccaa taaattttag gataattgac atttgaagtt gaagatgcct
     9001 aaaagaagcc gagaagcaac taatttagtt gcttttcagc ttcttttttg tttaacagtt
     9061 caatttcaaa ctgttctttt tctaattttt tgcggtaact gatcaagatt tgtacaggat
     9121 cgatttcttc ttttgacaat tgacgtttca aagataaatg agcttctttc ttttcataat
     9181 agaagtcagg agaaacgtca ccagaggtaa tcattgtttc tgcaagttga ccataacaaa
     9241 cgaggtagtg ctttttctga ctctcatctg ctgctaatgg catgctgaag gtgagcgatg
     9301 gtgttcttaa aaactgcttt tgttcctgga tccgtctaat aaaataagta actaattcga
     9361 tatctttttg aagcataccg gctttttcga aattcaactg atagatgaaa tgttgttgtc
     9421 tttttttcaa gtaagtcagt agctttttat ttcggccttg aaacagccct tggagttcct
     9481 tttttttctg ttcaaaagtc atttcctgta ggtcaggaag ctggactcgc aaagctaaca
     9541 aactaatttc agacaaccaa ggcatttgat aagtttcttc cattatacgc aaaatagacg
     9601 gcattttttt atagagacga aaaggcccgt atgttcgagc cgtaggagta tctgttaata
     9661 caaatccctt attggtaata tgtacataat tataattact gaaataattc atttgtcggt
     9721 tataaaaagg acggtaatgt tggatcaatt gacactcgag caataaagca tctaattccg
     9781 tgtctactac gacgaaatca aaatctgtta tatgatgaat catacgtaat actttttttg
     9841 aatgctgttt attctgatga aaatagctgc ttactctatt tttgagccgt tttgctttac
     9901 caacatagat gaccttacca tctcggtctt tcataagata gacacccggc agcatgggga
     9961 gagttttcat tttttctttt aacataggat ctccttttac gctttgaata aaaagactat
    10021 aacaaatttt gaaataatgg acaagtttta gggaattcta tagttctgtt cacagaaaat
    10081 acttt
//
LOCUS       DAJSMK010000085         9935 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.088, whole genome shotgun sequence.
ACCESSION   DAJSMK010000085 DAJSMK010000000
VERSION     DAJSMK010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.088"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(30..575)
                     /locus_tag="ON488_002141"
     CDS             complement(30..575)
                     /locus_tag="ON488_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HCR3232323.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(587..1279)
                     /locus_tag="ON488_002142"
     CDS             complement(587..1279)
                     /locus_tag="ON488_002142"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HCR3232324.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYKPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1298..1582)
                     /locus_tag="ON488_002143"
     CDS             complement(1298..1582)
                     /locus_tag="ON488_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232325.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1595..2158)
                     /locus_tag="ON488_002144"
     CDS             complement(1595..2158)
                     /locus_tag="ON488_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HCR3232326.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2385..3035
                     /locus_tag="ON488_002145"
     CDS             2385..3035
                     /locus_tag="ON488_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HCR3232327.1"
                     /translation="MIKRNWPWLLALVLLFLFGFSFVLGLLLIGVVLVLWGLFGSRRK
                     KGKQEEIPALTNELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAKLKAI
                     DLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIKNKQT
                     YEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQKD"
     gene            3159..4355
                     /locus_tag="ON488_002146"
     CDS             3159..4355
                     /locus_tag="ON488_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HCR3232328.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4456..5832)
                     /locus_tag="ON488_002147"
     CDS             complement(4456..5832)
                     /locus_tag="ON488_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3232329.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSFSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIISILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(5869..6735)
                     /locus_tag="ON488_002148"
     CDS             complement(5869..6735)
                     /locus_tag="ON488_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HCR3232330.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6824..7849)
                     /locus_tag="ON488_002149"
     CDS             complement(6824..7849)
                     /locus_tag="ON488_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HCR3232331.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYRLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(7867..8541)
                     /locus_tag="ON488_002150"
     CDS             complement(7867..8541)
                     /locus_tag="ON488_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3232332.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKP
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8722..9618)
                     /locus_tag="ON488_002151"
     CDS             complement(8722..9618)
                     /locus_tag="ON488_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCR3232333.1"
                     /translation="MKKRTGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     RNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYWKFKRQKQLRKNNRS"
     gene            complement(9692..9817)
                     /locus_tag="ON488_002152"
     CDS             complement(9692..9817)
                     /locus_tag="ON488_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCR3232334.1"
                     /translation="MKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKFKMKSEV"
BASE COUNT         3019 a         2149 c         1729 g         3038 t
ORIGIN      
        1 tttttatttt atcaaatcac tttgtttttt tataaaattt ctgcgcctag tgtggattca
       61 aaatgtctca atgcccattc atgtccaacg ggatcgaaac ttgccacggc atctttgaaa
      121 atatggagtt tgtatcctag attatacgca tcgactgctg tatgcaacac acagatatct
      181 gtacatacgc cggtcaaata aatatctgtg atctggcgtt ctcgtaaacg gatgtctaga
      241 tctgttccac taaaagcgga ataatgccgt ttgtctatcc aataaacatt ttcctcttgc
      301 tcatagtctt ggtataaact ttttaaagag ccgtacaatt cccgtccacc cgttcctatc
      361 acattatgcg gaggaaataa gcggttctcc ggatgaaagg aatcttttgg atcatgcgca
      421 tcaatggcaa aaacgacaaa atccttttga tcaataaact tctttgtatg agcagtcagc
      481 tttttttcaa ttacttgtcc tgctgtccca gtagtcagct ttccatcctc tgcaacaaaa
      541 tcatatgtgt agtcaatcga gatcaatgcg ttcatcttag tcctccttat acgagatgtt
      601 tgacaaattc gatcaccatt tctgctgatc gtttgcctgc gtcttcgata aattcgtcaa
      661 agctttgtgt cgccgagtga tctgctgtgt cgctcattgc acgtacgatc aaaaatggga
      721 tattgaactg acgagctgtt tgtccaacag cggctccttc catttcgcaa gctaatgctt
      781 cagggaaatt cgttaagatt tctttgattt tatctggcga gtcgacaaat gtatcacctg
      841 taacgatcaa tccttctttt gcgttcaaat tcgttgcttt tgctgcttta accatttcac
      901 tgcgcaaata tgtgcttgct tcataatata gaggcattcc tggtaattgt cctggtttgt
      961 agccaaatcc tgttgcatct gcatcaaaat aagctacttt gtctgatata acgatgtcac
     1021 ctacttgtaa gccttcaccg attccgccag ctgaacctgt attgatcacc atgttcacgc
     1081 cgtattgttg gatcaacaga cttgtggtaa tagatgctaa gacttttcct ataccggaac
     1141 gtacgacgat cacttcgtgg ttacctaatg aacctgaaat aaataaagcg cctgcgcgtt
     1201 cccatgataa tggttcgctt aggttctctc tcaaaatttt tacttcttct tccattgcgc
     1261 cgataatacc gattttcatc tttttaattc cttctttcta tataaatgcg attgctaaaa
     1321 aaaccacaca taacattagg ataacaataa taagagattt catcaaaaaa gagttccatt
     1381 tggtcgtctt ttcccgttcg ctgatccttg ttttcgtgat tggtttattc tttttgcttt
     1441 ctttacgata aaagctggca atcttttttt cttcttgctg ataagctgtt tctgcttttc
     1501 gctgtttttt taatgactcg cttgcttgtg cttgttgtcg cttgcgaagt tcgcttcgcg
     1561 taataagcgg tcctttggcc ataagccgat ccctctactt tcctttggtc aatagttccc
     1621 agtattgaat cgcataaatc gtctttgcat cacaaatcaa ctgatctttc atcgcttgtt
     1681 gcgcctcttc aagagttaga tgatacaact ccagtacttc gtcttcatct tgtgctaaag
     1741 gattctcgac cttctctacc ccttgtgcat gataaatatg aaggacttca ttagcaaaac
     1801 ctggtgaaag atacatcgaa gtaagatggc tcagcgactt cgcacgatag ccagtttctt
     1861 cttctaattc tctagctgct gtcatttcgg gattttgtcc ttctcctgga tcgatttttc
     1921 cagctggaat ctccaaaatc actttttcta aaggttttcg aaattgcttg acaagaagca
     1981 gacgatcttg ttcgtcaaaa gcaatgatcc caacaccgcc aggatgaaat accagttctc
     2041 tcttcgaagt tcctccatct ggcaaacgaa cttcgtctac agcaacatca ataatttttc
     2101 cgctatagat ttctttgcga ctgattgttt tttcttcaaa ttgctcattg ttcagcatat
     2161 cttctcctgc tttctttgta atcataactg ctttttttca tttttcaatt tttctcaaaa
     2221 actccttatt agtttaccat agataaacct tagattttct ctaaatatag aaaatccttc
     2281 tttagtccga tactctttct agtagtccgt atgctaaaat aagtatgtaa tcgaataacg
     2341 aaaagaattc aatactcaac gataaatgac atggagggtt tattatgata aaacgaaatt
     2401 ggccgtggct tctagcattg gtcttgctat ttctctttgg tttttctttt gttctaggac
     2461 ttttattgat aggtgtagtt ttagttttgt ggggactctt tggttcgcgc aggaaaaagg
     2521 gaaaacaaga agaaattcct gcactgacta acgaacttga aactcactat gaaaaaagcg
     2581 gtatgacagc gaatgaaatt tcattttttc gacaaacaat gaatcaaaca aaaaatgaga
     2641 tcaatcaatt gcaaatgaat atgcagcaga cagccaaact taaagcaatc gatctccgcc
     2701 atgatccagt caaagcagca aaagctttat tcaaagaatt ggtgaaagaa ccaaaccgac
     2761 tgcatgaagc aagtcagttt ctttatacgc atctgccgaa tctagttgat ttgacaaata
     2821 agtataatga gatcaatgac catgagatca aaaacaaaca gacctatgaa aaactagaag
     2881 aaagcgcgca gatcatcgac cagctgtcag ctttaatcgc acaagattat caaaaattcg
     2941 ttgctgagga tctagatgat atcgacgtag agatatctgt tgcgaaacag agcttaaagc
     3001 gtgataataa atatgaacca gaacaaaagg attaactctt ttgttcataa aagaagactc
     3061 ggaacattca gatgatgtct ggctgtttcg agtacttttt ctaaagtaga gacattcatg
     3121 taagaatcga gaacagattc aacaaggagg aattttttat ggatcataaa ccgactgaaa
     3181 caaaagatgt tacaccagtt aacgatacac ttgaagattt attgaacaac ccgttttcaa
     3241 ctccaacaga tacgctgacc acttcacaac aagcggagat tgatcagctc caagagcaac
     3301 agacagctgc tcgtttaatt gacaaactac cggcggaacg ccaagaacaa gctaaacagc
     3361 tagcagcaaa aatcgatgct aatgatgcac agtctgtcat cagctacgga tcggctgccc
     3421 aagcaaaatt aagtgaattc tcacaatcga tgttgaatca tgtgcaagca caagatattg
     3481 gtcctgtagg agattcctta actgaactga tgtatcgtct ccaagaagcc aatcctgacg
     3541 aactgcgtgc cggagaaggg aacatcttcc agcgtgtctt cgggaaggtc aaacaatcga
     3601 tctatgaagt gacagcaaaa tatcaaaaga ttggtgcaca aattgacaag atttcagtga
     3661 aattagataa agaaaaagac ggtctgctaa aagataatct gatgttagaa cagctttacc
     3721 agaaaaacaa agactacttt gatgcactga atatttatat cgctgctgga gaattgaaaa
     3781 tggaagaact tcaaacaacg atcattccag aagcgatgaa aagagcagaa gaaactggcg
     3841 atcagatgga tgttcagatt gccaatgatt acacgcaatt cctagatcgt ctggataaac
     3901 gtacgcatga tcttcgctta gctagacaga tcacgatcca gcaagcacca caaatccgtt
     3961 tgatccaaaa cacaaatcag gccttggctg aaaagatcca agcatctatc gctacagcca
     4021 ttccgctgtg gaaaaaccaa gtcgtgatcg cattgacctt gcttcgtcaa aaagatgcag
     4081 taactgctca acgccaagtc tctgaaacaa caaacgactt attgaagaaa aattcagaaa
     4141 tgctgaaaat ctcagccatc gaaacagcga aagaaaatga acgtggaatc gtggatatcg
     4201 agacccttca aactactcaa aatgatttga tcgaaacaat ccaagagaca ttgcgtatcc
     4261 aaaaagaagg aaaagaaaaa cgtcgtcatg cagaagtaga gcttggacac atggaagaag
     4321 atctgaaaca aaaactgttg gatttaaccc aatagatcac ctttcgcttg ttactaaaac
     4381 aaacgcccaa caacagttta ttacaactgt tgttgggcgt ttttcttatc tttcttctaa
     4441 cttctccatt ggagtctatt tctcattcat cttgctgtgt ccatagccat agccaaaata
     4501 aatgatcagt ccaataacca ttacgatacc gaacacgatc catgtcacag tttgcagacg
     4561 aagcatcaat acaatacaag tcaagatgga aatgattggc aatagcggaa cgaatggcac
     4621 tttgaattct ccagcttttg gtttgccaaa catttttctc aactttagta agcctagact
     4681 aacaagcatc aaataggcga gcgccatgat attcgttagt tccgctaata cattcaatgg
     4741 gaaaaatccg gcaaagaata cagctgccac accagcggca taagtcgctt ttttcggtgt
     4801 acgatgcttt tgatcgattt ctgtcataaa cttaggaagt aagccatcct tgctgacagc
     4861 aaacagtaaa cgagcaagtg aatacatcat cgagattgtt accgtcagta gcgttaaaat
     4921 ggcccctaca gcgatcaccg cgcccactgt tccatgtcct acatacctca ttgcaaaagc
     4981 cactgggtca ttgactccta gttcagtata cggaacgatt cctgtcaaga tcagcgtcac
     5041 gatgatgtaa aggacagtag caatcagtat cgaaccaatg attcctcttg gcacatcttt
     5101 ttgcgggttt ttgacttcct cggctgccat tgcaacggca tcaaatccca agaaagcaaa
     5161 aaacacaaga gctgcaccat ctagcacacc ggaaaaacca aaaggcatga atggctgcca
     5221 attatcaggt ttaacgaaaa atattcctac aatgataaac aacgcgatga taccaaattt
     5281 gacatatacc atggcattat tcaaacgtaa tgctttcttg gcttcaagcg acacgatgta
     5341 agtgacgaat atcactacga gcaccgcaat caagtcaatg tatgtaccat tttccggatt
     5401 gtacccgcca gttaatgctt gtggaagttc ggcccctaaa cttttcaaaa aaccttgcat
     5461 atagccagac catccggaag caacagagga aaccgctagt aaaaattccc cgatcaacaa
     5521 ccaccctgtc agccaggcag caaattcacc aaatacaaca tacagatagg catatggccc
     5581 accaatcact ggcactcgcg aagcaaattc tgcgaaactt agtccagaca aaatgacaac
     5641 gattgcagct aagacaaatg aaaatgacag tgctggacca gcattttgat tggccgcaac
     5701 ccctgtcacc acaaatattc ccgtaccgat gatcgcacca attccaagca tgatcaaatc
     5761 agacgttttt agttcttttt tcatctcact cgtatgattg agattgatct ctttcttacg
     5821 aaacaaatcc attgaagttc ctccccattt taggttggaa aacagcgatt aaactgtttt
     5881 catataccct aaaaggatac cacctaaaat gactaaaagg caaccaacaa taacataaat
     5941 gagctctttt ttcgtttttc tttcgccaag gatgaaaatc ccacctaaag tagagataat
     6001 gatccccatt tgtgaaagtg agaagccaac agctaaacca agtgatttga ctgttagaag
     6061 catgcagatg tttcctaagc cccataataa tccacagatc atgtttttcc acacaaactg
     6121 atcgacttta actttacgga aagcaaagaa gcttgcgcct aagatcattc cgatactttg
     6181 aggtaagata attgacatcg catccaaatt cgcccagttg acgatgatgg tatatacacc
     6241 ataaccaatc gtagagaaga tcaatgctct aaaaccctta ccaaaatcaa gcattttatt
     6301 atctgtatct atttttcctt cgtcatcttg tcgggcagtc aaatacgcac cgcttacaag
     6361 aagagctaaa gcaataatac cgtatacata atctttcgtt tgtgtccatt catggaagaa
     6421 aacggctccc gcaatcgtat tcaaaattaa ttgaaaacca gtagacaatg gtaaccctac
     6481 agaaacaccc atgtacttca ttccatggaa ctgtccattt tgtccaacac tccaagctaa
     6541 gccggataaa aatccgatca agaaaatcca aggggtgatt acaggactaa caacgaaaaa
     6601 gacaactaaa gaaaacagaa atgcaccgat cgtcattcct agtgtttgtt gattggcatc
     6661 gccaccaatt ttaccactta ctaaaccaat actaccccat gccaacatag ggactaatgc
     6721 tattaaaatt tccataacca atctcctttt atttcacatg ataagaaact tatcagcgaa
     6781 aacgttaaca acacaagcac tttttttcgt ttctaacgat tttctaacgt ttttcattat
     6841 aaaaatttaa gattgggaaa aataaagtca ttgttgtccc ttttccttca gttgattcag
     6901 ccgtcaaatg gatacctaat ttttcggcca gattttttgc taaataaagt cctaatcctg
     6961 ttgaatgtgt tttgctaagt cgaccatttc tcccagtaaa tcccttatca aagatccgtt
     7021 tcaagtcttc cgctgggata ccgatccctg aatctttaac tgaaaggctg actccttgtg
     7081 cttccttttc tatgctcaca atgatgtttc cgtgatccgg cgtatatttg atggcattac
     7141 taagcaattg gttgaagata aaagcgatcc atttagcatc ggtcaaaaca gtatgatcct
     7201 caccaacaat ctcgtagcga atattttttt ggataaaata atttgcctga ctgcgtatca
     7261 caggctgaat gattcctttt agcctatatt cttggatgag gtagtcccgc gaaaaactgt
     7321 ctagtcttgc ataatacaaa acttgttcta cgtattcatc gatttttgat aattcatttt
     7381 ctagtaatgt atacttttga tcgtcaatat cgaactcgat cgaacgaact agcaatttag
     7441 aagcggaaag tggcactttg atttcatgga cccatgagtc aatataatct ttttggtctt
     7501 gttgattact gattgctgat tgcattactt cttggtgttc acggatcagc tgattgatat
     7561 attcttctac cagtttttct tcttctgttc gtccaccgct caaatagttt tgcaaagggg
     7621 aagttttttg tatgtcggct aattttcccc accatcttct cttgctcaag taaccaccca
     7681 gcagataaaa aatcagaaag acgccctcaa tcaaagctaa ataagcaatt gtgctcaaat
     7741 caactttgat gtttggcgcc agccacatca caaagatcgt caatgcaata aaaaacagcc
     7801 atcccaagat caatgtccac tgatctttca aatatttaaa aaaattcatc ttaaccgctc
     7861 atcctttcag ggaacgatat atccctgtcc tacttttgtt tcgatatatc cttggatacc
     7921 tgcctgttcg atttttcggc gtaaccgatt gatgttgact gtcaatgtat tgtcatctac
     7981 aaatcgttcg tcatcccaca gtgctcgcag caatttttcc cgacttaaga tctttccatt
     8041 gtgcttcatc aaaataaata atagacgata ttcatttttg ctcaaatcaa tgatctctcc
     8101 gttgatttcc atacttccgt tgtcaacatt caacgtaatg ccattgtggc tcatcatttc
     8161 actagataat tctgtgtagt tgtaagaacg gcgaagtaat gcattgattt ttgcaatcag
     8221 tacatcgatt tggaaaggtt ttgtcacaaa atcatctgcc cccatgttca tagccatgat
     8281 catatccata ttcgtattcc tgctggagat aaaaatgatc ggtactttcg atacttcacg
     8341 tattttttga caccaataat agccatccaa aacgggaaga ttaatatcta gtaatacaag
     8401 ctgtggttct tctctttcaa agtctgagaa cacttgattg aaatcggtcg ttccaaaggt
     8461 ttcaaattgc catttctcaa gttcctccat gatcaattgt cgaatgatct cttcgtcttc
     8521 gactaccatg atttttgcca taaaaaatcc ctccatcttt cttcttgcta ctacaatatc
     8581 aaagaagccc ttgtgaaaca agttggctta cctggaaaat gtcattttag caaacgttaa
     8641 aaaaaactgg aaatatgcga tttaatcgct tttgtctttt caatacagct taaatttatt
     8701 atgttattct taacaattgg tctatgatct gttatttttc cttagttgtt tttgtctttt
     8761 aaatttccaa taacaccaat aaccgaaaag cgttagcact agcaatatac ctagaaggag
     8821 tataagtaat cgataaagat ggtatttttt tgtctgttct atctttgaag agacttcttc
     8881 tgtaaaggga actcgccttc ctgtcactag taatcggtga gtgttcacgg tgtaaggtgt
     8941 acaagtgata agtgtgacta gatcctgctt ttctctgatt gctaatgtat ttgtttttgt
     9001 tggaaggaca acaattttct caacgacttc ataagcgagc atccgaccat acacttcaag
     9061 atagaatcgg tcatcttgct ccatttcttc aagatccgta aagagttttt tctcagcaat
     9121 accgctatgg gcggtaatca cggaatgtgt actctctcct ccagttggaa aagaggtgcc
     9181 ttgcaggact gtcgctcctc tatctaacaa aagatcattc gtttcatcaa ataaaggcaa
     9241 gctaacattg attttcggaa tatagattgc tccgatcata tgttgttcgt agtattcttt
     9301 tcctggattt cggacatttc taaccgcttg ctcaaaagga tctttgactt gtcccattcc
     9361 tgggattact gatgtatgag caagcgtctg atttttcttt tcatgcactg ctaattgttg
     9421 ctcatgtttt tcttctttat cgcgttcaag ctgcttttga taattctcga tccttctttg
     9481 atccaaataa ttgctgagag catctgctaa aaatggatat gtaaaaactg cagctccggc
     9541 aagaaacatc actgccataa ataattgtaa taaaagactg atttgggttt gaggtctatt
     9601 acctgttctc tttttcattt tcttcacctt cttatttaaa aaaactgcag caatcggttt
     9661 tataaaggtt gctgcagctt atttttgttg cttatacttc agacttcatt ttaaatttac
     9721 ggtaccagct gtacgctcca atcatcaaac ttattccgat tagtaagaat gccaagagcc
     9781 cgttcccacc agtagcagga agtgacccgc gtttcatatt cggtactctt tctggccctg
     9841 gattttctac tcctacgatc tgaatttctt cattatagct tccataagag atgataaatt
     9901 cagtaaaggc tgcctcacct gttggaagta cataa
//
LOCUS       DAJSMK010000086         9862 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.089, whole genome shotgun sequence.
ACCESSION   DAJSMK010000086 DAJSMK010000000
VERSION     DAJSMK010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.089"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            1..432
                     /locus_tag="ON488_002153"
                     /pseudo
     CDS             1..432
                     /locus_tag="ON488_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            597..824
                     /locus_tag="ON488_002154"
                     /pseudo
     CDS             597..824
                     /locus_tag="ON488_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            950..1921
                     /locus_tag="ON488_002155"
     CDS             950..1921
                     /locus_tag="ON488_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3232335.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            2061..3374
                     /locus_tag="ON488_002156"
     CDS             2061..3374
                     /locus_tag="ON488_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HCR3232336.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            3417..4283
                     /locus_tag="ON488_002157"
     CDS             3417..4283
                     /locus_tag="ON488_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HCR3232337.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            4280..5128
                     /locus_tag="ON488_002158"
     CDS             4280..5128
                     /locus_tag="ON488_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3232338.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            5142..6614
                     /locus_tag="ON488_002159"
     CDS             5142..6614
                     /locus_tag="ON488_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HCR3232339.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            6631..7503
                     /locus_tag="ON488_002160"
     CDS             6631..7503
                     /locus_tag="ON488_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCR3232340.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(7739..9121)
                     /locus_tag="ON488_002161"
                     /pseudo
     CDS             complement(7739..9121)
                     /locus_tag="ON488_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            9583..>9862
                     /locus_tag="ON488_002162"
     CDS             9583..>9862
                     /locus_tag="ON488_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HCR3232341.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTH"
BASE COUNT         3024 a         1689 c         2039 g         3110 t
ORIGIN      
        1 tttaagtcta cttataattt actttggagg ttttgaatga atgaaattaa gcgcaataaa
       61 aattcttttg gtgtttattt aggagagcct agctcggaac agttaaataa aggtgaagct
      121 cgtcatgctc tatgtcgaaa tatattttat ggtagaaaag gcaaacttta tcaaacttat
      181 tacgacggta tggaggaaca gctcaacgca ttaggattag taactaatgc tatcatatat
      241 tggaattcac tatatttaga aaaagtcttt gaacaaatta aaacggaagg gttcgactgt
      301 tccgaagaag tgttacgcaa gcaatttcca ttaattagtg atcacattaa ttttgttggc
      361 aaatatagtt tccgctatga aaaagaatta tcgaatggaa tactacgtcc gttaaatata
      421 gagaattatt gagaatgttc gtcttttggt tcctaccgtg cattttcgca cggatgttcc
      481 agatactatt tttgaatgta taaaattgaa aacacaagaa tactaataaa tcaacgattc
      541 ttgtgttttt aatttttcac taccgtgcat tttcgtttct atgttccatg taccccaatc
      601 ttgaaaaatt aattaaagac ttagataaag ccattgacga cttagtcgtg gtgctaccgg
      661 agtatcaatg tttaaccagt atcccaggta ttggtcctgt ttaggctgct ggaatactcg
      721 ctgaaattgg tccaattgaa cgtttttctg atgaaataaa attgacaaag tatgccggcc
      781 tatattggcg acagagtcaa tccggtaaat ctgaatacga aaattttttt acgaaaagct
      841 tcacgtctaa tatctatttt aaaataaaaa tattcctgct aatttggaat cgtttccttc
      901 ttttggtata ataatacctg aaattctttt gagaggagtt gttcgtgaag tgaaaactac
      961 tatgaaggat gttgctgcgt tagcaggagt tggtgtgggt acggtatcta gagtaataaa
     1021 tggagtaaag gtgaaagagg ttaccaaaga aaaagtaatg gctgcaatta gtgagcttaa
     1081 ttatgagcct gatgaatatg ccagaggtat gaaaacgaat agtagcaata caatagctct
     1141 tattttacct acgatttggc atcccttctt ttccgagttt gcctactatg tagaggaagc
     1201 tctcagccaa aaaaattata agcttttttt gtgtaatgcg aacggcagtg cggaaaaaga
     1261 aaaagaatat atccaaatgg tcaagcagag taaagtagac ggaattatag gtattaccta
     1321 ttcagacatt gataaatatg tatcatcaaa tttaccattt gtcagtatag accgccattt
     1381 ttcggaacag gtttcttatg taacggcaga taattattta ggtgggcaaa ttgccgctca
     1441 agaactactt actcgtaact gtaaaaactt gtgctatgtt gggggtgttt caccttaccc
     1501 taacgaaaca aacaatcgta aagctggttt ttacaatatt tgtgaggaaa ataaaatagc
     1561 tgtgaaggta ttggatatgc ctgaaccaat tagcaattta gaggaacaat tgctcgcttt
     1621 tttttcggat aatcctgaaa ttgatagcat ttttaccatc aatgatttca tggctttgga
     1681 tgtgataaaa gcccaaaaaa aactagggaa ggaagcacct aaggattttc aaattattgg
     1741 ttttgatgga gtcaagctat cgttgcaaaa agactattta ctatcaacga ttgtacagcc
     1801 gatagaggaa atggccaagg tttcagtaga aacactcatg gcgatgattt taaatgaaga
     1861 accgcctaag cgtgtggtag taccggtttt ctttcacgct ggagagacga ctaaagagta
     1921 aaaaaccggt ttataacgat ttttttgaga taggttgaca gaaagtgatt tcaatgatat
     1981 cttaaaacca attaattgga aacgttacca attaattgaa aaataaaacg gaaacgtttc
     2041 aaaaaatagg aggaacatcg atgaaaaaga gaatgttagc aattgcagca attttagcat
     2101 taacagctgg aggacttgca ggatgtggca gtaaggagaa aagttcaggt agcagtgatc
     2161 caggagaaat taagatttgg gttcagtttt ctgatgaaac gcctgaagga aaagcttggg
     2221 cagagattgt gaacaatttt aatgatgaat acgagggtga atataaagct gttactgagt
     2281 atattcctcg tagcggaagc ggcggtggat atgaggataa agtaaatgct gcaattacaa
     2341 ccaataccct tcctgatgtt attacgttag atggaccgaa tactgcagct tatgctcatt
     2401 caggagtcat tgctccatta gatgattatt tgaaagatgc ggacatggat gatgtattag
     2461 acagcattat tcagcaagga acctacgatg gcaaaatgta tgcgtttggt ttctcagagt
     2521 ccagtgtggg tgtctattac aataagtcgc tgttcaaaga tgctggaatt acagaagatc
     2581 aattgccgac gttagaagat ccttggactt ggacggaatt tcaagcaatt tgccaaaagc
     2641 tgactgataa atacaaaacg cctgcaattg atatgcaaat ggcgtcggga gacgaaatgc
     2701 tgacctacgc atatacacca tttatatggt cgaatggcgg cgatgtcgtt aatgctgatg
     2761 gaaccaaagc cgaagactat tttaacggta aaaaatccgt tgaagcgttg gaatttattc
     2821 aagaattggt tgaaaaaggt tacaccacaa tcagtcctat tgaaaaagga tttgaaactg
     2881 gcaaatatgc catgatgctg agcggttctt ggacaatggc agatttagag gaaaactatc
     2941 aagagattga ttatggtatt ttgccttacc ccgtttcaga tgcaactggg gagttagttt
     3001 caccaaccgg aagctggcag ttagcaatga ctgagaaaac agagaaaaag gatgcttctg
     3061 cggcctttat taagtttgca accagtacag aatctagtcg tattatgagt ttagggaaca
     3121 gtgttctacc tatcagaaat tcaacagttg atttaattaa agatgaagtg tcggaaggaa
     3181 tgcaggtatt aattaagcaa aaccaacttt ctggacatgc ccgcccagtg gttgtagctt
     3241 atccgcaagt atctagagca ttccaacaag cagttcaaga tattagctac ttcgaggaaa
     3301 acccagatgt acaaaaagta gcagatagtc gcgctgctga aatgcaacag gcaattgata
     3361 cttcactaaa atagaagttt ctaaaggggg ccaatcaagt gttaaaaaaa ccgacaatga
     3421 aagacaattt gataggttac ggctttctag cgccagcttt gctgctgctg acgatttttc
     3481 tgatcatacc cgtaatcatg gtaatttatt atgcctttac tgattattat ttgttaacgc
     3541 cagatgctag acaatttatc ggcttagaaa attttaagcg actgttcgct gatccaattt
     3601 ttgtaaaaag tatttggaac acggctaaat ttgttgtttg gattattccg gtccaaatag
     3661 gggcagcttt aggaatggca cttattatca acaaaaatcg taaaggaaat atctttttta
     3721 aagtagcctt ttttgcgcca gtcgtgatgt ccttagtcgt tatttcgatt ttatggttgt
     3781 acttgttaaa tcctaatgaa ggtctggtta atacgctatt tgcaaagatt ggaattgctt
     3841 cgcagccttt tttgactagt cccaaacaag caatgtatac gcttgttttc gtatcggcat
     3901 ggcaaggtgc aggatatcag atgctgctgt ttttaggggg aatgcaaaat attccgcaag
     3961 acgtttatga ggcagccgaa attgatggtt tttctaagtt tcagcaattt cgctatatca
     4021 ccatgccatt attaaagccc acggcgattt ttattttact taccacattg atttcggcct
     4081 ttaaactaat cattcagcca atggtaatga ctcaaggtgg accaatgaat tctactatga
     4141 caatggttta ttacatttac caaactggat ttacagaccg tatggtaggc tactccagct
     4201 ccattgcgtt aatctttacc actatgattg gtttaattac aattgctcaa agaaaattgg
     4261 taaaggagga tgatccagca tgaccaagaa atttggaccg ctaatgatcg tagaatattg
     4321 tttgctgttc cttttagcgg cattattcat tttcccgatg ctgtggatgg tagtttcctc
     4381 tatgaagcct gaagcagatg tctatcaaaa tttagcttcc ttcaaagctt ttttacctag
     4441 tttgaatcca gctaattggt ttaaaactta tcaagaggtt atttcccggt tcagtgtggg
     4501 aacttattta ttaaacagta ttttttatgg tttaaccttt gcctgtgggt caatcattgt
     4561 aaactctttg gcgggttttg cctttgcgaa ggttaatttt tcaggcaaga aaattatctt
     4621 tggagctttg ttagctctgc tgattgtccc gatggagacg gttttaattc cgcaatttac
     4681 catcgttaat tcactaggct tagtgaatac tcgcttggca gtgattttac cagcgatggc
     4741 cagcgcgttt aatatctatc tgtttagaaa tttctttatc gcgattccag aagaaatcat
     4801 tgaatcagcg aaattagatg gtgcaaatat tgttaaaatt ttctttcaca tcatgctgcc
     4861 aatgtctaaa ccagccatag ccacagtagg tgtcttatcc tttatctcca gctggaatga
     4921 ttatatttgg ccgttaatgg tcttaactga cagcagcaaa ttttcaatgc aagtggcaat
     4981 tactacgatc aatactacac agccagttta tatcaatcaa gtgatggctg ttttaaccat
     5041 tgcaacgatt ccactgatta ttgtttatat cgttgcacaa aaatatattc tgcagggact
     5101 tggcggttct ggaacgggta taaaatagga gtgaatagtg aatgttgcaa aaacttttaa
     5161 aggccaatga gtttattgag aaaaatgctc aaacagtcaa tcaagaatac cggaataaat
     5221 ttcatttgat ggctccgatt ggctggatga atgatccaaa tggttttgtt tattatcaag
     5281 aggagtatca cttgttttat caatattatc cttacgacag catctgggga ccaatgcatt
     5341 ggggccatgc taaaagcaag gatctaattc actgggagca tttgccagta gcactggcac
     5401 caggtgaaag ctatgacaag gaaggctgtt tttccggcag tgccatagaa aaggatggca
     5461 agctgtattt gatttataca ggacacaatg ttgtggaagg gcaagttcga caagttcagt
     5521 gtttggcagt ttcagaagat ggcattcact ttgaaaaata tgccggaaat ccaatcatcg
     5581 cagaagatca cttagcttct gttgcaacga ccgaagattt ccgcgatccc aaagtgtttc
     5641 agcgaaaaga agactatttt actgtagtcg ctactaaaac tgcagatgct cgtggacaaa
     5701 ttgtgatgtt ccattccaaa gatttactaa cttgggagtt ttattccgta ttgctggagg
     5761 gaactccaga acaaggcatt gtatgggaat gcccagactt gtttgaacta gatggcaaag
     5821 aagtcttgat tctttctcct attcaaatga ctccacaagg caatgcttac caaaatacga
     5881 actcaactgt tgctttcatc ggtactgtcg attggcaaac aggcaaattt ctagtagaga
     5941 attttcatga aatcgatggc ggtttagatt tttatgcacc ccagacctgt gaaaacgaag
     6001 caggccaaag aataatgatt gcttggatgc aaatgtggca gcgtaaaata cctacgaatg
     6061 atctgggcca tggttggtca ggttccatga ccttgcctag agagctgagg gtggctgata
     6121 atcaattgtt gcaacggcca gtttcatcaa tttatcaagt aattgatccg caggaaagga
     6181 ttgaatgggc gaagactgaa gagaatcgct tcttactgaa ggacttagta tatgaccagc
     6241 actatttacg cttggaaatc aatttaaaac aggcaacgaa actagaactt cactatgcga
     6301 agggacccga ccatacatta ctgcttaact atgatgttga acgggagtgc tttactgctt
     6361 ccagggaaca catgccgtat gatttatcag gagctgaaaa ggaagtgttg aaaaagcgca
     6421 gtgtgacgat tcctttggaa aataattgtc taaccatcga aattttccgt gatacttcag
     6481 ctattgagct ttttctaaat gatcgtctga ctatgagtac aactttttat gagacagaaa
     6541 aaggacagga ttttcttttg ctggcagaca gtgaagtaac cttttcattg gaaagcggct
     6601 taattaatct atagaaggga gagctcagtg atgatttatg gttcaatcga agcaggcggc
     6661 acaaaatttg tgtgtgccat tagcgatgaa gaaatgacga tcaaggaaag agtgagcttt
     6721 ccgacaacga cacctgagga aacaatacct ttagtcattg acttcttcaa acaataccaa
     6781 gcagatttag cagggattgg gattggctca tttgggccta tcgatatcca tcgcgattcc
     6841 gccacttatg ggtacattac ctcgaccccg aaagtggcat ggcaaaattt tgatttcatc
     6901 ggtaccatga aaaaagaatt tccgatcccg atttcttgga caacagatgt caatgcggct
     6961 gcctatggtg agtatgtctt cggcagtggc aaaggattga gcagtgtcgt ttactatacg
     7021 atcggtacgg gtgttggcgg cggtgcctta caagaagggc gctttatcga agggtttagt
     7081 catccagaaa tggggcatat gctcgtcgtc cctcatccaa aagatgactt tgctggcagc
     7141 tgtccatttc atggcaactg tttagaaggg atggccgctg gacccgccat cgaaaaacgc
     7201 ttagggaaaa aaggacaaga ggttgcagaa gatgatcctt attgggaaat cgaagcctcc
     7261 tatattgctc aatgtgccta caatacaacc ttgatgtttt ctccagatgt gatcattttt
     7321 ggcggtggtg tgatgaaaca acgccatatg ctgcaaaacg tccacgacgc atttgcaaaa
     7381 ttggtcaatg ggtatgtcga aacacctgag ttaagcaaat atatcgtgac cccagcatta
     7441 gaagacaacg ctggaacgct cggttgtttg gcattggctc gagaagcggt cttacattca
     7501 taaacgaaaa aaggctcttc gacatttagt gttggtagag aaagatacaa ctgaaaattt
     7561 agtcataacc agttaggcag agtgcttaac tggtttttgt tttacttgga agatcaagcc
     7621 ttgaatgaga taagttcttg ctcgaaagtt atggaaattt cgatagccgt aggctacttg
     7681 tattgtgcaa tagtttttta caaaaaaaag ggggtgcgga tatttttttt ggaccttttt
     7741 aacaaatata tctttgcttc ttccgatatt gaagagggct tagccttcct aaagataact
     7801 taattcgttg attattatac caatgaatat aatcatccaa tttgtttata aactgattga
     7861 ttgttgtatt cttccagtca cgttgataaa acatctcgtt ttttaatcgt ccaaagaaac
     7921 cttcgcacgc tgaattatct ggtgaataac tctttttaga catagagtga agcaagttgg
     7981 ctttgttcca atagtccaac taacaatagc accatcgtaa caatcgacaa gtggtgataa
     8041 gtagattttc cctgcgagaa ttctaaattc agtaatatct gttaaccatt tttcatttgg
     8101 cttctttgct ttaaaattcc gatttaataa attggggtgt gcaggagaaa tttccccagc
     8161 atacgaagaa tacttttttc gtctagaaaa tttaacaaat agattttcct cagtcatcaa
     8221 tctacgtaca actttttcag aaagcttttt acccatattt tttaaagctt ggtgaattct
     8281 acggtaacca tacgcacaga agttatgatt gaaaatcgtg ataattaatt tgacgttctt
     8341 tgtaatactt atctggtttc tcaagtgctt gtttttgata aaaatagctg cttttaggaa
     8401 actggagctg ttgaagaagc tctttcaagg tgaactgatt tcgtaaggca tcaatcaata
     8461 tcgttttttc ttgatttgat agacaaagaa gattgacgcc tttttctttt tttagcagtt
     8521 cagccgctcc ttcgagtaat gctttttcga gctgtaattg gtgtacttgt ttttgtaagt
     8581 cttctacttc ctttaaaagt agctcttttt gtttttcctg attttttaaa gtcatacaca
     8641 atggaaaatc ctttccaaga accgtgtttt tccattgata tagagtaact ctactaattc
     8701 ctccagattc ggctaaattt ttcctattag tttgcggttt atagaatttt ttcaacacag
     8761 cttctttttg atcttgtgtt aactttaccg cactttttcg gagttttcta gctcctggtg
     8821 caagttcttc acaccgctgc cgcaaggact ctctattagg ataaccaagc atgcgaatgg
     8881 ttcgtgcata acattgacca tattcaaaat aatgattcac cgctattcgt ttttgttctt
     8941 cagaatactt tgattttttt cggtgctcct gatggagctc tccggattcc aaatactctt
     9001 tataccattt ccgtagtgca ccaatcgacg gataccctaa ttctcgaatg gttgcagcat
     9061 aagagcaatc gtattttaaa aataactgaa ttgcccttac acgctctttg tgggaaaaca
     9121 cacggacatt cctcctaagt ttattttttc gtccaggatt atgtccgcac ccccttgctt
     9181 tctgatgact tattctggtt ctttgagtgt caatgcatag atgtgatgta gctagttaga
     9241 aaaaaatttt gaatactctt tttttctttc agactccttt ttaagtaaga ttttgaagtg
     9301 tgagttacgg ggtcagaaac ttaaaagttt ttgatccttt attttcaagt ctgatttggc
     9361 agcttttcgg cagctcattt atttatggtc agaaatagat gctgaaattt taatctatta
     9421 gcaaatagtc cagaacgtat gaagaggagt cggatatcat ttgtcattaa caccataaat
     9481 atttataaaa ttcgtgttca cctacaatta aatttaatat ataatattcg ttgtaagggc
     9541 ttataatttt ttgttaatga acaagatagg aagaaacatt taatggacag ttttcagaga
     9601 ttgtcactag taaatcaatt tgagttattg gctaaatttg aggaccaaaa cagatcttat
     9661 tatgaaagaa aaatcgaaat attgagagaa ggttacgagt atcattatga tgatgaaatt
     9721 tggagtgatc tttctgagcc atttccgaaa gaagattctc gatttgtatt agatgtattg
     9781 aacatgtatc gagatatcaa ttttagtaaa tcaaagctaa acttagatga aaaccaaatt
     9841 actaattcat actatactca tt
//
LOCUS       DAJSMK010000087         9751 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.091, whole genome shotgun sequence.
ACCESSION   DAJSMK010000087 DAJSMK010000000
VERSION     DAJSMK010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9751
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.091"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(734..1912)
                     /locus_tag="ON488_002163"
                     /pseudo
     CDS             complement(734..1912)
                     /locus_tag="ON488_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1942..2352
                     /locus_tag="ON488_002164"
     CDS             1942..2352
                     /locus_tag="ON488_002164"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232342.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            2433..3053
                     /locus_tag="ON488_002165"
     CDS             2433..3053
                     /locus_tag="ON488_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232343.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            complement(3351..4400)
                     /locus_tag="ON488_002166"
     CDS             complement(3351..4400)
                     /locus_tag="ON488_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3232344.1"
                     /translation="MPSIIKRGNSYRAQISLYNHGQHKKLTKSFSSKKEATRWALENE
                     LEKGNGKQLAERTTTFADFFENWIHIIKKNDVKETTFQNYQRTSQVVKKLFGDIQLKD
                     LNDIVVQRKIDKYAETHSRKTTHEVLLKIKTALRDAYARGYLATDFANLVKTRGKVLD
                     KRNRVLSITELKKLRTYVINHRENEFNILVLLALETGMRRGELLGIRPEDLFEYGIHV
                     RRSLSPTSEDTSLKTKNSRRDISINQEVYDILKSVPIKDNGYFFDPDGFQQSAKLARL
                     LKKLDIPKTTFHGLRDTHASFLFSQDIDIAYVSKRLGHINIQTTQNYYLELMPEKKHQ
                     QDADALNLLNSLSNL"
     gene            complement(4506..4703)
                     /locus_tag="ON488_002167"
     CDS             complement(4506..4703)
                     /locus_tag="ON488_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002403995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCR3232345.1"
                     /translation="MKNTITTYELPYLLTREQASHFLGIDPKSFDKFVRANDELERFM
                     IGRQERYTVTSLINFIKTHSI"
     gene            complement(4793..6049)
                     /locus_tag="ON488_002168"
     CDS             complement(4793..6049)
                     /locus_tag="ON488_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HCR3232346.1"
                     /translation="MNQVNQHDLGESIRVSREERGWTQRYLAEKVGISRSLLSKVEKG
                     TRQLSAEKLNLILDSLQEEIVPVNRVLIDYLTIHFFSNQHLKLIEAIIGMPIERFEEL
                     DYAPKGYIGQYVWNQVITIRYSIDDTVKGTVMEFSGQGCKHLAMRLKTAKSNWQEFFR
                     KVLDYQGNFTRIDFTLDDFVGSLSIPELKRKVTLGHVWTTFQVSESHGGTDIINNESN
                     GETLYLGSKKSQCRFCFYQKDYEQRKRRGISLEEAEVKNRFELRYRKEKAQSLAKIIS
                     KTHDLTKLFFELLNGAICFYDRAPNDPGAKVDAKWAAFIGNHGATTISLETIPQSFEK
                     SMNWLIHSVSPTLAFIQEVDNHFDSNLINEIISCGELSSRQQKILENLIAEPDYYQEE
                     VEFYIQCLQNMKAAKIHKKSKAQLTH"
     gene            6211..7023
                     /locus_tag="ON488_002169"
     CDS             6211..7023
                     /locus_tag="ON488_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232347.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGTQENQYILEMLQKKAGKLDPKIEGLIVDELKQ
                     AGLVSEKEMDRMIEFFIINLIPPTEQDQFTYQCIDEKKQLYLGSTKFGKEAQLYLHHD
                     NQNHILHILPFTFSNFSVDRLLVYLANQESYSYFGKHLPKELVEKAILLYSINQLTVD
                     VRIAPLVYSKETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNVAYPSSK"
     gene            complement(7244..9325)
                     /gene="cadA"
                     /locus_tag="ON488_002170"
     CDS             complement(7244..9325)
                     /gene="cadA"
                     /locus_tag="ON488_002170"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HCR3232348.1"
                     /translation="MSCTNCAAKFEKNVSQIPKVTDAKVNFGAGKISIEGEATIAEIE
                     AAGAFENLKVQSEHDTEPRIETKEPFVKRNWNLLVSLFLIILALGSQVVNGEDALLTE
                     GLFILAIIIGGFSLFKEGFSDLLKLNFSMESLMTIAIIGAAIIGEWTEGSIVVILFAI
                     SEALERFSMDKARQSIRSLMDIAPKEALIRRNNVEQMINVSKIEVGDIMIIKPGQKIA
                     MDGQVIKGHSSVNQAAITGESVPIEKNINDDIFAGTINEEGALEVKVTKHVNDTTIAK
                     IIHLVEEAQGERAPAQAFVDKFAKYYTPTIMVIAALIVIVPPLFFNGDWNTWLYQGLS
                     LLVVGCPCSLVISTPVSIVSAIGNSAKNGVLVKGGIYLEEIGGLKAIAFDKTGTLTKG
                     TPTVTDFTTVDSKDEEKYFSIITALESYSQHPLASAILKEADNRAISYKSVVVDEFTS
                     ITGKGIQGNIEGITYLVGSPKLFESILTDNSKIIENYQRLQQQGKTAMLLGTDKQILA
                     VIAVADELRESSKAVIEKLHDLGIEHTIMLTGDNATTAQSIGKQTGVTEIKGDLMPQD
                     KLDYIKSLKETYGKVAMVGDGINDAPALAASTVGIAMGGAGTDTALETADVALMGDDL
                     QKLPFIVKLSRQTLRIIKQNITFSLGIKLLALLLVVPGWLTLWIAILADMGATILVTL
                     NGLRLMKVKSK"
     gene            complement(9357..9716)
                     /locus_tag="ON488_002171"
     CDS             complement(9357..9716)
                     /locus_tag="ON488_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HCR3232349.1"
                     /translation="MKNEICEISCVHEDKVLLGKEKLQTEDISSLKSVFKILADENRL
                     KIIYALSYEDELCVCDIAATIEATVATTSHHLLSLKKNGIVVSRKVGKLVYYSIKNDK
                     FVQLLNSKLYLEDEVLV"
BASE COUNT         3039 a         1756 c         1680 g         3276 t
ORIGIN      
        1 taatgaaaaa cgagaaggaa gatgacttta aagtagttta gtatgaaggt cgattgataa
       61 aacgatgtgg attaatgcta aataatgagt aatttttcaa taatacaaaa actgtgtaca
      121 gtattagaag tagagaaacg ctagcgtcga aaaaaagata tttttcgtga aaagtaatag
      181 gggctaaaaa gaaagtatac aatttattta tgtttctaag catataaaaa agagcgttga
      241 aaggaatatt tccccttcaa cgcttctttt ttagaagatt ttaatgacca tctcaacttc
      301 attttcaggt ttaggtaatt catggaagct tgtgtttatc gtgcttaatt gatcaactaa
      361 ccatgtttta ctttttgact cgtagacaaa tctaaaatta atatcattgt tctcgtgttg
      421 aagaggtttc tccaaataat ctggtgaata ttcatagtca acgtaacctg ctaatacaaa
      481 agaaagcagt ccattattta gtgtcagatt taacggatgg tcgtaagctt ttattttttt
      541 aatgtcatat tgtacatctt atgaagactt aatgactact tgtagtcaat agatttaaag
      601 tatttatttt ctcatttatg tatcaagaat aaatactgat ataataaaaa ttatatcaat
      661 gttttgatga agtaatttgg agggagcgtc aataattttg tgtaaataac tcgtccttct
      721 gcaaaataat gggttactca gtaaacattg aagctaatgt atccgtcact tgttggaagc
      781 ctttatggct tctatttaag aatttttgat tgtatgtatc aaagatggat actaggaaac
      841 gctctagtga ttcttcattt tgaaactgct cttttctgcg gctgtatttc ttgatttgtt
      901 tcttgaaaga ttcgattaaa ttagttgagt aaatgcttcg gcggatacca ggcggaaact
      961 cataaaaagt caataaatct tgatttttta tcagtgactg cgtcacttta ggataagttt
     1021 tttgctactt ctcaatcata ctccctaaaa aggtatttgc ctcttccttt gagctagctt
     1081 gataaacagc cttaaaatca tcacagattt cttttcgatc tttgacacgt actttatgag
     1141 caatattacg ggaaacgtga acacagcaat gttggtattt agctttagga taaatctggt
     1201 gaatcgtatc tttcatgcct tttaagccat cggtaataaa cagtaagaca tcatgaaccc
     1261 ctctggagta aatgtcctgt aacaactcat tccaaacgta ggtcgattca gtcggagcaa
     1321 tcgcataact tagtacttct ttagtgccgt cttctcgtat accaatggca atatagattg
     1381 cttctttgga gacggtttgc cgttttaaag gaatataagt agcatccatg aaaatagcga
     1441 catacttatc atttagagtt ctaactttaa atgcatttac ttcttcagtc agcactttag
     1501 tcatgttgga catggtttgg ggcgtgtagt gatgcccata cattttctca atcaagtctg
     1561 cgatttccga catggtaata ccttttcgga agaggtgaat gacggtctcc tctaaggtat
     1621 cattcgtccg tctataagca ggaacagtct gttgcttgaa ctcgccgttg cggtcgcgcg
     1681 gaatctggag atgaagttcc ccgtactcgg tcttgaccgt acggtcatag gagccgttac
     1741 gagaattccc cgtgttaaaa ccaatgcgat cgtacttttc gtaatcgagg aaagccgtta
     1801 actccgtttt gagaagcgta ttgacagctt tttccaaatg gacacggaat aattcattca
     1861 aatcgccttt gttcgctaga gtctttagaa tttctgtagt aaaatcgttc atatggaagt
     1921 cctcttttct gtgaatgtgt tgtggtaact ctattctaca gaagggactt ccttttttct
     1981 atttacacaa aatattttac actctcgtca aatataaaaa ctagtacgaa attaatttgt
     2041 aaattattta agcttgataa aataagcaat atcgatgatg taaagtccaa gatattaaca
     2101 agaaaagtaa gcgaaccagt aaagctaacg gcacaagata aaaaaaatgg aattgttctt
     2161 tatggtgatg atgcaaagta taactataat tgggatacct cctcagaagc tgaggtatta
     2221 agtattccta ctaccgatac ttcaggggaa aaagtcacct ttaaaataaa ttttataacg
     2281 gcaatttcta agttggagta tgggaagcaa aaaaagagag ataacaatga tcaatatcta
     2341 cctaaaaaat aacgaattaa tgatgcatat gttaaagttg tttttttgaa ttaaacaact
     2401 caatttattc agttatatgt tcatcgcagc aagtgaacat taatcgagtt ataaaattaa
     2461 taggagctaa aaatataaat aaagttcgat cagaatttat ttttccagaa gattttttta
     2521 actggttttt ttatcaattc agtgaatgca agcgactctt aggtgagaat tattacttaa
     2581 aaggaatcgg cggatttatg gggaatgtgg ctgatgaaca aaatattata aaaggaatat
     2641 ctgaacaaac atcagagctt acagtaacta aagcatttat aagtaatggt gaaagtttga
     2701 aaaatgtaac tgcgcgaatt agaaaagaaa atgaagtaga cattgttttt ggaattgacc
     2761 atgaatgtaa ttcagtgata tatgtaacac aatcagcaaa tttaattctt tttgagaatg
     2821 gttgcaagga cgattttatg gtggtctatt tgtacgatat actaattcca aaacttcgtt
     2881 ccttatatat gtcttctgaa agtatttttg tgagtgaaca aaagggatct ttctcgaaaa
     2941 aaataggtat tgaagtaatt gaatcgatta tgtgtcataa tcatattacg ctagaagaat
     3001 tagaaatttt gatagggcaa aaaaataata acacgaaaat acaagtttct tagaaatcat
     3061 tttttattga gatatctaga taaatgattt attcttcaat caaccaactc gccaagctga
     3121 ggtaatgttt tgaggtaatg ataacataca actttttata ccctagtaaa actctataaa
     3181 caaagactta ttaatttcgc atgaaataca ttcctgtaaa atgcaataaa atagagtttt
     3241 gtttaaccag gtcttaagaa agcccgtaaa gcttcacagt tctcaaaacg ttaatcaatt
     3301 ccttattgta tcaacgttta caagaatttt ttggttcaag ttggttcaaa ttataaattt
     3361 gacaaagaat ttaagaggtt taaagcatca gcatcttgct ggtgcttttt ttctggcatc
     3421 aattcaagat aatagttctg cgttgtttga atattgatat gacctaagcg ttttgataca
     3481 taggcaatat caatatcttg tgaaaataga aaagaagcat gagtatctct taggccgtgg
     3541 aaggtagttt ttggaatatc tagttttttc agtaatctgg cgagcttagc agattgttga
     3601 aagccgtcag gatcaaaaaa atatccatta tctttaatcg ggacagattt tagaatatcg
     3661 tagacttctt gattaatgga aatatctcgt cttgaatttt ttgtttttaa cgaggtatct
     3721 tcagaagttg gactaaggga acgtctgaca tggataccat attcaaagag gtcttcggga
     3781 cgtataccta aaagctctcc gcgtctcatg ccagtttcta aggcaaggag tacaagaatg
     3841 ttaaactcat tttctcgatg attaatgaca taagtacgca gtttctttaa ttcggtaata
     3901 gaaagtacac ggtttctctt atctaaaact ttccctcgtg ttttgactaa atttgcaaaa
     3961 tcggtagcaa gatagccacg agcataagca tcacgtaatg ccgttttgat tttcaatagt
     4021 acttcatgag tggttttacg agaatgagtt tctgcatact tatctatttt tcgttgtact
     4081 acaatatcgt tcaaatcctt taactgtata tcgccaaata atttcttcac cacttgagaa
     4141 gtcctttgat aattttgaaa agtcgtttct tttacatcgt ttttctttat gatatgaatc
     4201 cagttttcaa agaagtcagc aaatgttgtt gtacgctctg ctaattgttt tccatttcct
     4261 ttctccaatt cattttctaa ggcccaacga gttgcttcct ttttagagct aaatgatttt
     4321 gtcaatttct tatgttgacc atgattgtaa agtgagatct gagctctata tgagttacca
     4381 cgtttaatta tactaggcat ttataacaaa tcctttcact gaaagatggt tgataaatgc
     4441 tagttgaata caccgtcatt ctacatggcg aaaagcatct aatcaaccat cctacgatat
     4501 tttagctaga tagagtgcgt cttaataaaa ttaatgaggg aagtgacagt gtatcgttct
     4561 tgtcttccta tcataaaacg ctctaactca tcgtttgcgc gaacgaattt atcaaaagat
     4621 tttggatcga tccctaaaaa atgagaagct tgttctctag taagtagata gggcaattca
     4681 taagtagtta ttgtattttt catagtttat ttcctttcca aaaatgtttt ttggctgaca
     4741 caaggaaatg tgctatactc aacttgtcta gggcggagta cgtttataca ttttaatgtg
     4801 taagctgtgc tttgcttttt ttgtgtattt ttgctgcctt catattttga agacactgga
     4861 tataaaattc tacttcttcc tgataataat caggctcagc aatcaaattt tctaatattt
     4921 tttgctgcct tgaactaagt tccccacagc taataatctc gttaatcaaa tttgaatcaa
     4981 aatgattatc tacctcttga ataaatgcga gggtgggaga aacgctgtga attaaccaat
     5041 tcatactttt ctcaaagctt tgaggaattg tttctaaaga aatggtggtt gcgccatgat
     5101 tgccaataaa ggctgcccat ttggcatcga cttttgcacc tggatcattt ggagcacggt
     5161 cataaaaaca aattgctcca ttaagtaact caaagaatag tttggttaaa tcatgggttt
     5221 ttgaaataat ctttgccaag ctttgcgctt tctcttttcg ataccgtagt tcaaagcgat
     5281 tttttacttc tgcttcttct aaagaaattc ctcgtcgctt tcgttgttca taatccttct
     5341 gataaaagca aaagcgacac tgactcttct ttgagcctaa atacaaggtc tcaccatttg
     5401 attcattgtt tatgatatcc gtaccgccat gagattcact cacttgaaaa gtggtccaca
     5461 catggcctag tgttacctta cgcttcagtt ctggaatgct gagactcccc acaaaatcat
     5521 ctaaagtaaa atcaatccgt gtaaagtttc cctgataatc taatacctta cggaagaact
     5581 cttgccagtt tgattttgcg gtcttcaaac gcatggcaag atgtttacag ccttgacctg
     5641 aaaactccat tacggttcct tttaccgtat cgtcaatgga ataccgaatc gtgattactt
     5701 gattccaaac atattgccca atatagccct ttggcgcata atccagttcc tcaaagcgtt
     5761 caataggcat gccaataatt gcttcaatca actttaaatg ttgattcgag aaaaagtgaa
     5821 tagttagata atcaatcaaa acacgattaa ctggaacgat ctcttcttgc aaactatcca
     5881 gtataagatt caatttttct gcacttaatt gtctcgttcc tttttctact ttcgataata
     5941 acgatctcga aatccccact ttttctgcta aatatcgctg ggtccacccc ctttcttctc
     6001 gagaaactcg aatcgattcc ccgagatcat gttgattgac ttggttcata gaaaaacctc
     6061 cttctgctat taaattgtca aagaaccatc agacttattt taagtacaaa tcgattgtac
     6121 gcctgtattt attttaagtc aatacatttt gacttttttt aagtacaagc gtatactgaa
     6181 tttaagaact tatcatgagg aggagttttc atggagatag acaagcaagc agtgggcaat
     6241 cgaattcggc agattcgtca agagttaaag ttgagtatgg agaaatttgg caaactaatt
     6301 ggtgatttac cacgaagtac agtcaataac tgggaacgtg ggattaacct tccaaaaacc
     6361 gaaacccttc accaaattgc agaaataggc catgtcacca acgaatatct tttgtatggt
     6421 actcaagaaa accaatacat tttagaaatg cttcaaaaga aggcaggtaa gcttgatcct
     6481 aagattgaag ggctaatagt agacgaactg aaacaagccg gtcttgttag tgaaaaagaa
     6541 atggatcgga tgattgaatt ttttattata aacctcattc caccaacgga acaagaccaa
     6601 tttacttatc aatgtatcga tgagaaaaag cagctttacc ttggttcaac taaatttggt
     6661 aaagaagctc aactctattt acaccatgat aatcaaaatc acattctgca cattctgccc
     6721 tttacctttt ccaactttag tgtggatcgc ttactcgtct atttagcaaa tcaagaatcc
     6781 tattcctatt ttgggaaaca tttgcccaag gaactagttg aaaaagccat tcttctatac
     6841 tcgatcaatc aattgaccgt cgatgtgcga attgccccgt tggtctattc aaaagaaaca
     6901 gcttcttatc agtacacaga ggacaatcaa tatctactag aacaacaata tctttatcta
     6961 ccattcgtga tggaagtcga gaaagaacgt ctgttaaacg tagcgtatcc atcatcaaaa
     7021 tgaggtgaca agattgataa gcatgtgaca aagaaaacac tgctaggaca ctcccaaatg
     7081 ggtagttgtc acagtttcct gttctttgtt agccccctgt tagaaagagg ggcttgccca
     7141 tgcagtccgg ctacgccgtc ctgcaacagc attaaaaaga ggaaagacta gcttatacgg
     7201 cgctgccgtc gctagtcttt cctcttttta tgctactact tgtctattta gatttaactt
     7261 tcatcagtcg taagccgttc aaggtaacta atatagttgc tcccatatca gctaagatag
     7321 caatccataa cgttaaccag cctggaacta caagtaataa tgctaatagt ttgattccca
     7381 atgagaaggt aatattttgc ttaatgattc tcaatgtttg tcgacttaat ttaactataa
     7441 agggaagttt ctgtaagtca tcacccatta aagctacatc agctgtttct aaagctgtat
     7501 ctgttccagc gccacccatt gcgataccga ctgttgaggc agctaatgct ggtgcgtcat
     7561 taataccatc accaaccatg gcgacttttc cataggtttc cttaagtgat ttaatataat
     7621 ctaatttatc ttgaggcatc aaatcgcctt ttatttcagt tacacctgtt tgttttccga
     7681 ttgactgagc agttgtagca ttatcaccag tcagcattat cgtatgctcg attcctaaat
     7741 catgtaattt ttcaatgact gctttacttg attctcttaa ctcatcagct actgcaatga
     7801 ctgctaaaat ttgtttatct gttcctaaga gcattgctgt ttttccttgt tgctgaagtc
     7861 tttggtaatt ttcaataatc tttgagttat ctgttaagat agattcaaaa agctttggac
     7921 tccctacaag ataggtaatc ccctcaatgt ttccttgtat tccttttcca gtaattgaag
     7981 taaactcgtc aacaactact gatttataag aaatcgctct attatcagct tcttttaaga
     8041 ttgctgacgc gagagggtgt tgagaatatg attctaatgc tgtaataatt gagaaatatt
     8101 tctcttcgtc ttttgaatca actgtagtga aatctgttac cgttggtgtt cctttagtca
     8161 atgttcctgt tttgtcaaag gcaatcgcct tgaggccacc aatttcttca agataaatac
     8221 cgccttttac caaaacacca tttttagcag agtttccaat tgctgaaacg atagacacag
     8281 gtgttgagat tactaaagaa caaggacagc caacaactaa taaagagagc ccttgataca
     8341 accaagtatt ccaatctccg ttaaaaaata atgggggaac gatgacgatt aatgcggcaa
     8401 tcaccataat ggtgggtgta taatatttcg caaatttatc gacaaatgct tgagcaggtg
     8461 ctcgttcacc ttgtgcttct tcaactaggt gaataatttt ggcaattgtc gtgtcgttca
     8521 catgctttgt aactttgact tcaagtgcac cttcttcatt aatcgttcct gcaaagatat
     8581 catcattaat atttttttca atagggacag attcaccggt aatcgcagcc tgatttactg
     8641 aggaatggcc tttaatgact tgaccatcca tagcaatttt ttgtccaggc ttaatgatca
     8701 taatatcgcc tacttcgatt tttgaaacat taatcatttg ttcaacatta tttcttctaa
     8761 ttaatgcttc tttcggagca atatccatta gggaacgtat tgattgtctt gctttatcca
     8821 ttgaaaaccg ttctaaagct tcgctaattg caaataagat aacaacgatt gagccctcag
     8881 tccactcgcc aataattgca gcaccaatga ttgcaattgt cataagagat tccattgaga
     8941 aattcaattt taataggtct gaaaatcctt ctttaaacaa actaaatccg ccgataataa
     9001 tcgctagtat aaataatcct tctgttaata gcgcatcttc accgttaact acttgagatc
     9061 ctaatgccaa aataattaaa aacagtgaaa ccaataggtt ccagtttctt ttcacaaaag
     9121 gctcttttgt ttcaatgcga ggttctgtat catgttcgga ctgaacttta agattctcaa
     9181 aagctcctgc agcttcaatt tccgcaatag tcgcttcgcc ttcgatagag atttttccgg
     9241 caccgaaatt tacttttgca tcggtaactt ttggtatttg agaaacattt ttttcgaatt
     9301 ttgccgcaca attcgtacag ctcaatcctt caacccgata gacttgtttt tttcactcat
     9361 actagcacct catcttctaa atacagtttg gaatttagta gttggacaaa tttatcattc
     9421 ttgatagagt aataaaccaa tttccctact ttccgactca caacaattcc attttttttc
     9481 aatgataata aatggtgtga ggttgttgcc acggttgcct cgatagttgc tgcgatatca
     9541 catacacata attcatcctc ataacttagg gcgtagataa tttttaagcg attctcatca
     9601 gctaaaattt tgaagacact ttttaagctc gaaatatcct cagtttgtaa cttttctttt
     9661 cctagtaaaa ctttatcttc atgaacacat gagatttcac aaatttcgtt tttcatacag
     9721 ctcctccttt attctaatgg atatttgaat g
//
LOCUS       DAJSMK010000088         9387 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.092, whole genome shotgun sequence.
ACCESSION   DAJSMK010000088 DAJSMK010000000
VERSION     DAJSMK010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.092"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            2..77
                     /locus_tag="ON488_002172"
     tRNA            2..77
                     /locus_tag="ON488_002172"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35..37,aa:Asp,seq:gtc)
     gene            79..149
                     /locus_tag="ON488_002173"
     tRNA            79..149
                     /locus_tag="ON488_002173"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:111..113,aa:Gly,seq:tcc)
     gene            163..236
                     /locus_tag="ON488_002174"
     tRNA            163..236
                     /locus_tag="ON488_002174"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:197..199,aa:Ile,seq:gat)
     gene            261..348
                     /locus_tag="ON488_002175"
     tRNA            261..348
                     /locus_tag="ON488_002175"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Ser,seq:gct)
     gene            370..441
                     /locus_tag="ON488_002176"
     tRNA            370..441
                     /locus_tag="ON488_002176"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Glu,seq:ttc)
     gene            464..553
                     /locus_tag="ON488_002177"
     tRNA            464..553
                     /locus_tag="ON488_002177"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:500..502,aa:Ser,seq:tga)
     gene            566..639
                     /locus_tag="ON488_002178"
     tRNA            566..639
                     /locus_tag="ON488_002178"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:600..602,aa:Met,seq:cat)
     gene            658..730
                     /locus_tag="ON488_002179"
     tRNA            658..730
                     /locus_tag="ON488_002179"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:691..693,aa:Asp,seq:gtc)
     gene            734..806
                     /locus_tag="ON488_002180"
     tRNA            734..806
                     /locus_tag="ON488_002180"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:767..769,aa:Phe,seq:gaa)
     gene            811..881
                     /locus_tag="ON488_002181"
     tRNA            811..881
                     /locus_tag="ON488_002181"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Gly,seq:tcc)
     gene            894..967
                     /locus_tag="ON488_002182"
     tRNA            894..967
                     /locus_tag="ON488_002182"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:928..930,aa:Ile,seq:gat)
     gene            979..1050
                     /locus_tag="ON488_002183"
     tRNA            979..1050
                     /locus_tag="ON488_002183"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1012..1014,aa:Glu,seq:ttc)
     regulatory      1239..1318
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1316..2509
                     /locus_tag="ON488_002184"
     CDS             1316..2509
                     /locus_tag="ON488_002184"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HCR3232350.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            2639..4111
                     /locus_tag="ON488_002185"
     CDS             2639..4111
                     /locus_tag="ON488_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3232351.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4194..4982
                     /locus_tag="ON488_002186"
     CDS             4194..4982
                     /locus_tag="ON488_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HCR3232352.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5049..5717)
                     /locus_tag="ON488_002187"
     CDS             complement(5049..5717)
                     /locus_tag="ON488_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HCR3232353.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            5832..7544
                     /locus_tag="ON488_002188"
     CDS             5832..7544
                     /locus_tag="ON488_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232354.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            7547..9319
                     /locus_tag="ON488_002189"
     CDS             7547..9319
                     /locus_tag="ON488_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232355.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         2767 a         1643 c         2121 g         2856 t
ORIGIN      
        1 tggttccgtg gtgtaggggt taacatgcct gcctgtcacg caggagatcg cgggttcgat
       61 tcccgtcgga accgccatgc gggtgtagtt tagtggtaaa accacagcct tccaagctgt
      121 tgtcgcgagt tcgattctcg tcacccgctt ttagtttttt atgggcctat agctcagctg
      181 gttagagcgc acgcctgata agcgtgaggt cgatggttcg agtccattta ggcccattag
      241 tacaaaatct tattggtttt ggggaagtac tcaagtggct gaagaggcgc ccctgctaag
      301 ggtgtaggtc gggaaaccgg cgcgagggtt caaatccctc cttctccgtt tcaatatttt
      361 gttttacctg gcccgttggt caagcggtta agacaccgcc ctttcacggc ggtaacacgg
      421 gttcgaatcc cgtacgggtc attaatttaa tatagtttta catggaggat tacccaagtc
      481 cggctgaagg gaacggtctt gaaaaccgtc aggcgggtaa aaccgtgcaa gggttcgaat
      541 cccttatcct cctttttcat attatcgcgg gatggagcag tctggtagct cgtcgggctc
      601 ataacccgaa ggtcgtaggt tcaaatcctg ctcccgcaat taaaaactaa aaacattggt
      661 tccgtggtgt aggggttaac atgcctgcct gtcacgcagg agatcgcggg ttcgattccc
      721 gtcggaaccg tttggctcgg tagctcagtt ggtagagcaa tggattgaag ctccatgtgt
      781 cggcagttcg attctgtccc gcgccattat gcgggtgtag tttagtggta aaaccacagc
      841 cttccaagct gttgtcgcga gttcgattct cgtcacccgc ttttagtttt tatgggccta
      901 tagctcagct ggttagagcg cacgcctgat aagcgtgagg tcgatggttc gagtccattt
      961 aggcccattt attttattgg cccgttggtc aagcggttaa gacaccgccc tttcacggcg
     1021 gtaacacggg ttcgaatccc gtacgggtca tggaagatac tttttgagta tctttttctt
     1081 tttatctgaa agaatgattt taaaaagctt agcagagtta tctttatgga tgattgtgct
     1141 aagctttttt ggacagttct aatgtaaaat atttttatat tttttaagca aaaaaatgaa
     1201 aaaatacgag cagaaaactg ttttatctgc tatacttggt tcgttgcaag ttcccgaaag
     1261 gatccgcagg acggagatgc cttgtaaccg aatttaacta gggggaatca ttataatggt
     1321 agaaagacac ttatttacat cagaatctgt ttctgaagga catccagata aaattgctga
     1381 ccaaatcagt gatgcaatct tggatgcaat tttaaaacaa gatccaacag cacgagtagc
     1441 gtgtgaaacg tctgtaacaa ctggtcttgt tttagtattt ggagaaatat ctacgacggc
     1501 atatgtagat attcaaaaag tcgtacggga aacaataaaa gaaattggtt atacacgtgc
     1561 aaaattcgga tttgatggag atacagcagc tgtattggtt gcgattgatg aacaatctcc
     1621 tgatattgct caaggagttg atgaagcact tgagatccgg gatgaagata aaaaagacgt
     1681 attagatgag attggtgctg gtgaccaagg tttaatgttt gggtttgctg tagatgaaac
     1741 accagaattg atgcctttac caatcgcttt gagtcatcgt ctggtacgac gcttggcaga
     1801 tttgcgtaaa tcaaatgaat taacgtattt acgtccagat gcaaaatctc aagtaacggt
     1861 tgaatatgat gatcaaggac aaccggaacg cgtagataca atcgttattt caacacagca
     1921 tgatgatgca gtagataatg aaacaattcg tcatgatgtc atcgaaaaag tagtgaagga
     1981 agttattcca gctgaattat tagatgatca aacgaaatat tatatcaatc cgactggccg
     2041 atttgtcatt ggtggtcctc aaggggatgc cggattaaca ggaagaaaaa tcattgttga
     2101 tacgtatggc ggttatgctc gtcatggtgg cggtgctttt tctggtaaag atgcgacaaa
     2161 agttgaccgt tctgccagct atgctgcacg ttatattgct aaaaacattg ttgcagcagg
     2221 gcttgctcgc aaagcagaag tacagctagc ttatgcgatt ggtgttgctc aacctgtttc
     2281 gatctcaatc aatactttcg gtactggaac ggttccggaa gaagaactga ttgctgcagt
     2341 gagagaaaac ttcgatcttc ggccagcagg aatcatcgag atgcttgatt tgcgtcgtcc
     2401 gatttacaaa caaacagctg cttacggtca ttttggtcgt acagatgtag atttgccttg
     2461 ggaacatacg gacaaagtag atgcgttgaa agcaagttta gcaaaataag ttatattcag
     2521 ctggaacgat cgccaagtgg tggttgttcc agcttttttt atggcagtta acctcttgaa
     2581 aaagatagta attatttatc tatttttaga tcctgtcata atgaaaggga ggaataagat
     2641 gaaaaaagaa acaaatgtta ctttggtcac agtgagtatt ttcattgcaa cgttcatgac
     2701 ggctattgaa ggtacaatcg taacaaccgc tatgccaacg attgtcggtt cattacatgg
     2761 aatggaaatc atgaactggg tattttcgat ttatttgctg acaaacgcta tgcttactcc
     2821 gatttacgga aaacttgcgg ataaagtggg acggaaacca atctttattt ttgggacatt
     2881 attgtttatt atcggttcgt tattttgcgg tttatctcaa agcatgattg ggttgattgc
     2941 tgctcgtgcg attcaaggga tgggtgctgg ggcaatgatg ccagtagctt tgacgatcat
     3001 cggcgatctt tattctattg aaaagcgagc aaaagtttta ggtttgaata gttcagcctg
     3061 ggggattgcc agtgtttttg gaccgcttgc gggaggattc atcgttgaaa cgatcagctg
     3121 gcactggatc ttttttatca atgtgccgat cggaattcta ttaattattt tgatttggct
     3181 atatttaaat gaaccaaaaa tcatacatga gtctaaacca atggatattt ttggtagttt
     3241 tagtttgatg gccatgcttg tctcattgct gttagggttc caattattag gagacgaagg
     3301 aatgagtccg cttgtttctg ctttgctgct aggtagtatc gtaatgttag gtatttttgt
     3361 ttttgccgaa aaaagagcta aagatcctgt catcatgatg catttattca aaaatccact
     3421 atttgttgtg gtcaacttgg ctgcagcatt ggctagtggt tttttgatgg gaatcgatgt
     3481 ttatatccct atgtggatgc aaggtgtatt agggctgaat gcagcaattg gtgggctggt
     3541 attagcacca ttatcactag tctggatggt cggttctttc cttgcaagca agtggatgac
     3601 tcaaatgaaa actcattggg tcttgagaat tggactacta atcgcagcta ttgggggcgc
     3661 ttggttgtat cttatgcctt tcagaagtaa ctatttatgg ttttttgcta tatcaacggt
     3721 catcggtata ggcttaggtg tgaccatgac tacctcgact gtcagtgcac aaaatagtgt
     3781 atctcgtgac cagcttggtg tagcaacttc ttttaatacg ttagttcgaa caattggtca
     3841 aacagtcatg gtttctattt ttggtttatt gataaatggg gtaactaaac gagaacttgc
     3901 agcagcaaat ttaacaaatg atgcagatat catgaataaa ctggtgaatc cacaaacggc
     3961 taaatatatt gatgcggata ttttgttacc attaagaaaa attctttatg atgggttaca
     4021 ttccgtttat ctagttggct tgttactcgt gatcattgct ttggtcttaa cgcttttcgt
     4081 tcatgaaaaa agtggtaaaa taaaacagta gtttcggtta agatatgtac gtagccgaat
     4141 cattcaaatt taaagttatt caaaaataac ttcttactaa ggaaggcgaa aatatggcat
     4201 ttattcaagc aaatatttat tcgaatgtgt tagaaatgga agtcaatcta aatgtgatac
     4261 taccgcaaac aacaaaaaag gtgattggca ccagttcaga gcaagagaca acggatatac
     4321 ctgttttata tttacttcat ggaatgggtg gcaatcatag tgtatgggaa agacgtacgt
     4381 cgattgaacg ttatgtagca aactacggat tagctgtcat catgccatct actgatcttg
     4441 gctggtacac agatacagtt tatgacatga agtattggac attcattgca gaagagctac
     4501 ctgagatttg tcatgaatta ttcccgcaat taacaagaaa aagagaaaaa acatatgccg
     4561 ctggattatc gatgggcgga tatggcgcgt taaaactagg ccttgcaaaa tcagaaaatt
     4621 tcgcagcagt aatctctctt tcaggcgctg tttctgtagg aaatcgaatg gatgatcttt
     4681 tgatggttcg taaagcatct ttttgggaag ggatctttgg accattggat caaatcgaag
     4741 gttcaaaaaa tgatccgcaa tacttattga aagaactagt aaaaagcgga aaaccagttc
     4801 caagatttta tatggcttgt ggggaatctg attttcttta tcaggcaaat caggaaatgg
     4861 tatctgctat gcaggaacaa ggcttggcgg tcacctttga acaaggacct ggcgatcata
     4921 actggatctt ctgggaccaa tggattcaac gtgcattggc gtggctaatg gaagaaaaat
     4981 aaaaaaagag tcttaaaaag atagctccta tagagatcac aaacatagtg atctctatag
     5041 gagctttttt actgctcgtt ttctcttctt ttattttgtt ggcataagcc ttcaatatag
     5101 gtttgtgcac tcgttagaaa gagtgctttt tcattcaatt ctgcatggga ctgcatactt
     5161 tctttaaatc cctctaattg attttcaact acataattac gcataaatag aactgtttct
     5221 ttcaaaaatt catttccgtc cataattttt tgtcgaagct gctgttcatg ctgctgatcc
     5281 attaactgtc caatcaataa attgtggaga gaggcaatgg cctgatgact ttgggtgact
     5341 gaaaatcctt cacgaacaag taattggatc atttgctcca aatgttctaa tcgactcgga
     5401 aaagcgggca cagtattgat ttctaattct gccccacaag ggaaacgtgt ataaaggtca
     5461 tagtaatttt ccatatactg cagcaactgt tcattccaag gcaaagttgg atctggaagc
     5521 gctaattctt cttccattgt ttcagccatt ttttgcaaga gctgttgttt gtttttgaaa
     5581 taccaatata aagcaggtgc ttgaacatga attctgtttg cgatgtttcg catggaaagc
     5641 tgcgaaagag cttgtgtttc agccaggata tcaaaggcgg cctgaatgat gattgcttga
     5701 gaaagcttta tttccatttt atcaacctcg tgtattgcat tatcttttta aacatggtaa
     5761 attgttagtc ggtctaattt tacagtgtta aattagtcct gtcaatttaa acaaaggggt
     5821 gtaatcaacg aatgaaatta atcttacgac atgcgaaaaa atataaagta gctgttttta
     5881 tttccttgct gtccgtagca gtcatggttg cagcagcatt atggcaacct aagttactac
     5941 agcaagtatt ggaagctatt attacagaag ataatgatga aatgaaaaca attggtattt
     6001 acctgatcag tctggctttg ctaggattag ccgcaggtgt aacgaacacg attttctctg
     6061 caaaagtagc tcaaggcgta agtgcagata tccgagaaga agcatttcga aagatccaga
     6121 cattttcatt tggaaatatc gaacagttct ctgctggaaa tcttgttgtt cgtctaacaa
     6181 atgatatcac gcaaatccaa aatttagtga tgatttcttt gcaatcactt tttcgaattc
     6241 cattcttatt tattggtgcc ttcattttag ctatgatcac gatgccgcaa ttatggtgga
     6301 tcatcgtagc gcttatcgtt acggtatttc tgattacggc actttcattt acaaggatgg
     6361 gcaagcactt catgatcatt caaaaactga ttgatcgtgt gaatagcatt gcaaaagaaa
     6421 acttactagg gattcgtgta gtgaaatctt ttgtacaaga agaaaaccaa ttgaagtcat
     6481 tcagcaaagt aagtgaggac ttaacaaaac acaacatcat agtcggtaca ttattttctg
     6541 tgatgatccc gtccttcatg ctggctgcca atttggctgt ggttggggcg atcttttttg
     6601 tgagcgatct tgttaaagat gatcctacgt taattggtgg aattgcttca ttcatgaact
     6661 acttgatgca gattatgatg gcaatcatta ttggcggaat gatgatgatg atgacttcaa
     6721 gagcagccgt atcgctgaag cggattgcgg aaattttaga tgctgaacca gatcttactt
     6781 atttagacgt tccagaacaa gagttgacgg gttctgtcac ttttgaccat gtttcttttc
     6841 gttatcctgg tgaggataca gatacgctta aagatatcag cttttctatc aaacctggag
     6901 aaatggttgg tatcgtcggg gcgactggtg ccgggaagtc aacactagca caattgatcc
     6961 ctcgtctatt tgatccgaca gaaggcaaag ttgaagtagg tggtgtagat cttcgtcaag
     7021 taaatgaaaa gagtttaaga caaacggttt cctttgtttt gcaaaaagca attttattct
     7081 caggaacgat tgctcaaaac ttgcgccaag ggaaaaagaa tgcaacagaa aaagagatgg
     7141 aacatgcttc ttctattgct caagcaaaag aattcatcga aaagttatct gatcgttacg
     7201 aagcaccaat agaagaacgt agcagtaact tttctggtgg tcaaaagcaa cgtttatcca
     7261 ttactcgtgg cgttatcggt aatccaaaga tcttgatcct agatgacagt acgagtgcac
     7321 tggatgctcg ctctgaaaag ctggtccgag aagcactcga tcgagatttg aagggaacaa
     7381 cgacgattgt catcgcacaa aaaattgctt ctgttgtcaa agcagaccgc atcttagtat
     7441 tggatgaagg cagattagtc ggcgaaggaa cccatgagga attggtagct ggaaaccgtg
     7501 tctatcagga aatctttgaa actcaaaaag gaacggagga gtaagtatga ctgatctaat
     7561 aaaagcaagt aaatttttct atcactattt gaagcggtac aaactctcct ttttctttat
     7621 ctttatcaca gtgatcattg ctacctatct acaagtaaag gcacctcaat acatcgggga
     7681 agcttttcaa gaattagcta attacgtagg aggcttgatg caaggcgtag acgataaaag
     7741 caaatttgtt tctgtaatat ggaaactctt gctgttttat gtactagcta gtgcagccaa
     7801 ctttatctat agtattttgt tcacacaagt agtagggaag tcaacgaacc gaatgcgtat
     7861 cggtctattc aacaaattgg aaaaattgac gatccgtttc tttgattctc atcaagacgg
     7921 tgaaatttta agtcgtttta ccagtgactt agataatatt caaaatagtt tgaaccaagc
     7981 tttgcttcaa gtcatcacga atgctgtttt acttgtcggg atcttgatca tgatgttccg
     8041 ccaaaatgta gagttagctt gggctacaat tgcttccact ccagtagccg ttttgatagc
     8101 tgtcttgatt atccgcaaag cacggaaata tgtggatctt cagcaagatg aagtggggaa
     8161 actaaatggt tatatggatg aaaaaatcag cggacaacgt gtcatcatca caaatggctt
     8221 acaagaagaa acgattgaag gattcttaga gcataatcaa agtgttcgcg aagcaacctt
     8281 caaaggacaa gcttattctg gtctactatt tccgatgatg caaggaatgt cactggtcaa
     8341 tacagcgata gttatctttt tcggcggctg gttagcatta aatggtgatt tggaacgttc
     8401 ggtggcatta ggcttagttg tgacattcgt ccagtattca caacaatatt accaaccact
     8461 gatgcagatt tcatctggat acagcatgat ccaattagcg attacagggg caagacgatt
     8521 gaatgaaata tttgatgaaa aagatgaagt caaaccagaa aacggtaaag catttgatgg
     8581 tgttgaaaaa ggtcttgcgt tgcagcacgt agattttggt tattctccag aaaaactagt
     8641 cttgaaagat gtctcgatca atgtggacaa aggagaaatg gttgctcttg ttggtccaac
     8701 aggatcgggg aaaacgacga tcatgaatct gctaaaccgt ttttacgatg tcaatgatgg
     8761 ttcagtagtc atcgatggaa tagatatccg agattatgat cttgatgcat tacgtagaca
     8821 tgtaggaatc gttttgcaag aatctgtatt gttctccgga acgatcaaag acaatatcac
     8881 attcggcaaa ccggacgctt cagatgaaga agtcatcaat gcagcaaaac aagcgaatat
     8941 tcatgacttc atcatgacgt tagaaaaagg ttatgataca gagatatccg aagaaaataa
     9001 cttattcagt acaggtcaaa agcagttgat cagtattgct cgaacgatca tcacaaatcc
     9061 atctttattg attttggatg aagcaacaag taatgtagac acggtaacag aagcaaggat
     9121 ccaaaaagca atggatgaag caatcaaagg aagaaccagc tttgtgattg ctcaccggct
     9181 gaaaacaatc ttgaatgcag atagaatcgt tgtcttgcgt gatggggaag tcattgaaga
     9241 aggcagtcat catgagttat tagcagaaaa tggattttat gcggaacttt atcataatca
     9301 atttgtattt gaaagttaaa ttaaaagaac ctcgttataa cggggttctt tttatatatt
     9361 ttatgttgtt tgtttttata aggggca
//
LOCUS       DAJSMK010000089         9291 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.093, whole genome shotgun sequence.
ACCESSION   DAJSMK010000089 DAJSMK010000000
VERSION     DAJSMK010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9291
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.093"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(22..690)
                     /locus_tag="ON488_002190"
     CDS             complement(22..690)
                     /locus_tag="ON488_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCR3232356.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            824..1111
                     /locus_tag="ON488_002191"
     CDS             824..1111
                     /locus_tag="ON488_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232357.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1527..3065
                     /locus_tag="ON488_002192"
     CDS             1527..3065
                     /locus_tag="ON488_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HCR3232358.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3062..4027
                     /locus_tag="ON488_002193"
     CDS             3062..4027
                     /locus_tag="ON488_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232359.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            4014..5336
                     /locus_tag="ON488_002194"
     CDS             4014..5336
                     /locus_tag="ON488_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCR3232360.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5399..5503
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5577..6320
                     /locus_tag="ON488_002195"
     CDS             5577..6320
                     /locus_tag="ON488_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232361.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6335..7327
                     /locus_tag="ON488_002196"
     CDS             6335..7327
                     /locus_tag="ON488_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HCR3232362.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7339..8076
                     /locus_tag="ON488_002197"
     CDS             7339..8076
                     /locus_tag="ON488_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232363.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8066..8788
                     /locus_tag="ON488_002198"
     CDS             8066..8788
                     /locus_tag="ON488_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HCR3232364.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8872..>9291)
                     /locus_tag="ON488_002199"
     CDS             complement(8872..>9291)
                     /locus_tag="ON488_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HCR3232365.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         3042 a         1603 c         1965 g         2681 t
ORIGIN      
        1 taaagtagtg aaaaataaga atcagtgctc taactgttca agaggatcaa gtggttcaaa
       61 tgtttctgta gtctgttttg cttccaattg gggcaaaaca gatccaattt ccagatactt
      121 cactttattc aatgtataag atagaataga acagctaagt aatgtataca gaaaatgtgt
      181 gagatccaaa taaagcaagg agacaactaa aataccaaaa gtaatcaaga aaagactttt
      241 gccaatctta atatgaaaat atttttcaat ggcttgataa atgatatctg ttccgcctgt
      301 gcttccgccg aatcgaaaga cgagaccgca accaatgcca gaaagaatac ctgtcatcaa
      361 actattgatc agtagactat ctacagcaaa atgtatatga aggctctccc ataaatgtaa
      421 aaagaaaact agcgcaaatg ttccgacgat cgtccggaga aaagcgtgtt ttccaaaaag
      481 aaacaatgag ataagcaata aaggtaaatt aaaaagcagt gaagtgacag aaggagcgaa
      541 tccaaaaaga ttatgcaaaa gcaaagcaat accagtaacc ccaccatctg ccagcttaga
      601 tggaatattg attcctgtca cagctaatcc gtagattcct gcgcctaaaa tgattccgca
      661 caattctgta aataaattta attttttcat ttctagcctc ttttcttttg aaaattttca
      721 gcaacttctt tattatactg acttatactc ttacttcaag aggaaaatga aaaaaaatta
      781 tttttggctg tttcttttta tttatcaaat aaggagtgga aaaatgcgag cagcagactt
      841 attgacaatt cttacaaaat cacccaaaaa aacagagtat caaggagttt ttttggctca
      901 agaacaaaaa ctggtgcctg tgacaatggt ccagataaat aaagcaaatc aatttatctt
      961 tttatttgaa cacggcaaag caccacttgc tatgaaagac atctttcttt ttttgatgaa
     1021 gaaccgtgag aaagctgttt attatcagtc aaaagaagaa ctcattcctc tttatggagt
     1081 gaaagagata gaaaataaag tggtgatata agtaaaaata agaaaacaag acgtttatga
     1141 tgtcaaaaca accatttttt acatttttgg caaaaaagtg tcatgataca gtataatatt
     1201 cgttgaacag gccaataaag gtgttctccc ccacgagatt tctactttat tggctgtttc
     1261 tttttattaa aataaaagtt gtgtgtgtaa aaaagatata gctgattcca agtgacaatt
     1321 tcgtatagat ttttatggta ttcgtagtga aaaaacgaga accaaaaagt tgatccgact
     1381 ttgttgcttg gattcttttt ttgtcagcat atttagaggt atttttttct tttttttgtt
     1441 cgtgctgtaa ggttaaggca agacaagtta gttgggaaaa aggaaagaaa tgtttatact
     1501 taaagaataa cagaaaggaa ggtcgcatga ataattttat acaaacatta agtgaaagaa
     1561 aaggcgagtt gctggaagct gcatttcaac atctgtccat ttctctcatt tctttgctga
     1621 ttgcagcact gattgctatt cctttagcga tttgggcagc caatcataaa aaaatggcag
     1681 aagtcttatt gcagatcacg ggtgtgctcc aaacgattcc ttcacttgcc ttattaggtt
     1741 tacttatccc atttgtaggg atcggaactg ttccagcatt gattgcactt gttatttacg
     1801 ctttgcttcc gattttccaa aacacgtata ttggtctagc tgaaattgac ccgtctattg
     1861 aagaagcagc ggtagcattt ggtatgtcca gaatgagacg cttgctgaaa gtagagcttc
     1921 ccatcgcatt acctgtcatt atctcaggta tccgaactgc cttagtttta atcatcggta
     1981 cggctacttt ggcagcattg atcggagcag gtggattagg gacatttatt ttgttaggta
     2041 ttgaccgaaa tacacctgtt ttgacattga ttggtgcgat cagttctgcc ttgcttgcaa
     2101 ttatattcag cggactgatt cgctggttgc agcataagaa acctcgatat tccatcatta
     2161 ctttagcagc agtggtgtgt ttatttggcg gcgtttcttt atatcagtct gccttgttta
     2221 aaaatgaaac catcacgatt gctggaaaat taggagcgga acctgaaatc ctgatccaaa
     2281 tgtataaaga attgattgaa gacaacacaa aaacagaagt tgaattaaaa ccgaattttg
     2341 gcaagacgag ttttttgttc aatgcactgg atcaaggtca aatcgatatc tatcctgagt
     2401 tcacaggtac tgtcctagaa agcttggtga aggtacctga agcaatgaaa agtgctgatt
     2461 tgacaaaaga aaaaacatat gacgaagcag aagaattatt gaataagcaa ttcgatatga
     2521 cattattaaa accaatggct taccaaaata cgtatgcctt ggcagtcaag agatcttttg
     2581 cgaacgaaca tcaacttaaa aagatttccg atttggcagc tatctctgat cagatcaaag
     2641 cgggattcac actggaattt attgatcgtt cagatggata taaaggaatc caagaagcat
     2701 atggcttgaa tttttcaagt gtacaaagca tggagccaag tttgcgttac caagcaatca
     2761 ataatggaga tgtcaatatt gtggatgcct attccacaga tagccagctc aaggagtacg
     2821 atctagtgac tctagaagat gatcgagggt tattcccagc ttatcaaggc gcaccgctga
     2881 tgaaaaaaga ttttgctaaa gaacatcctg aaatcgttaa agcactgaat aaattaagcg
     2941 gaaaaataac agaggatcaa atgattgata tgaattacca agtcaatgtc gaaaagaaaa
     3001 agccgacaga agtagcacga atcttcctga aaaatgaagg attagtaaag gaggaagatc
     3061 agtgactaaa ttaatcgagt tcaaacatgt gcaaaaaaag tatgatggaa agtatgtcat
     3121 cgatgaccta aatctggcaa tcaaaaaagg agaaatcttt gttttggttg gtccttccgg
     3181 tagtggaaaa acaactactt tgaaaatgat caatggatta tctaaaccat cagcaggaga
     3241 catctacttc aaaggaaaat cgttaaatga atataatctg cagaaaatgc ggtggaatat
     3301 gggatatgtg ctgcagcaaa tcgctttgtt cccgaccatg acagtcaagc aaaatattga
     3361 agtcatccct gaaatgttag gttgggaaaa gcagaaaaga gcagaccgtg tagatgaact
     3421 tcttcaaaaa gttggcttat ctcctgatat ttatcgagat cgtatgccta gagagttgtc
     3481 tggaggagaa cagcaacgga tcgggatcat ccgagctatt gctgcaagcc cagatgtgat
     3541 tttgatggac gagccattta gcgcattaga tccgatttca agaaactcat tacaagaatt
     3601 ggttttgtcc ttacacgaag aattgggcac gaccatcgtt ttcgttacgc acaatatgga
     3661 agaagcaatc aagctaggtg atcgtattgc atttatgaag gatggagaaa ttatccaatg
     3721 tgacacacca gagcagttat tgatgaatcc taaaaacgac tacgttcggc atttctttga
     3781 tgaaccgaaa cagacgaaag agtggcgagt agaagattta gtcgtcaatg gatatttctt
     3841 aaatgaaata ccagaaaatg ctcgtcaaca agtttgcttt gatacgccta tgaaagaagt
     3901 atattcgctt ctttcggtgt atccaagcat tgtgatagta gaaaagcaaa gaagtattgg
     3961 gtcgctgaca agtaaagaaa tctttgcttt tttaagtcga gaggaggaag gaaatgaaaa
     4021 catatgatgc aatcatcatc ggttcaggtg tgagcggctt aagtgctgct tatggattga
     4081 aagaagcagg taaaacagta ctagtggtcg aagaagatct atggggcggg acttgtccta
     4141 accgtggatg tgatcctaaa aaagtcttgt taagtgcagt agaggcacgt aatcgggtaa
     4201 aacaattgag tggaaaaggt tttaacgaga tcccaactgc caactgggaa gaacttcaaa
     4261 aattcaaacg aacatttacg gatccagtcc cagaaagccg aaaaaaacaa ttagcagaag
     4321 ctgaaatcga tcatctttca ggaaccgctc gttttttgga tgattcatct attgaagtca
     4381 acgaagaagt cttccatgcg gattacttag ttttggcaac cgggcaaaga cctacgatct
     4441 taccagtgga gggaaaggaa tacttgaaaa ctagtgcaga ctttttatca ttgcctgtac
     4501 tgcctaaaga aatcattttt atcggtggtg gttatattgc ttttgagcta gctacgattg
     4561 ccaatgctgc agggagcaaa gtaaccattg tccatcataa tcaacggcca ttaaaagaat
     4621 ttgaggcgtc tttggtagag gaagccgtcc atcaaatgga agcatctggc attcagtttg
     4681 cttttggtgt tgaaacccaa aagatcattt cagaaggtac tcgctatcgt ttagtcggaa
     4741 aagagacgga attagtagca gatatgattt tttgtgcgac tgggagacag ccgaatacag
     4801 aatctttagc acttgagcaa gcgaatatcg tctttgataa acacggaatt gcagtcaatg
     4861 attatctgca aacgagcaat ccaaaaattt ttgcgtgtgg agatattgtt tcaaggaaaa
     4921 ccccaaaatt gacaccagtc gccacttttg aaggaaatta tgtagctaag cggataacgg
     4981 atgcaacaag cgaacctatc aaatatccga ttatacctac gatcgtctac gccagtccta
     5041 aacttgctga agtaggagtt acaaaaagtc acgcctcttc gtcagatcaa gtggtagaga
     5101 tggatcttac cagttggttc acctatcatc gtgtcaatga accagttgct aaggctgaat
     5161 tgacctttga ccagcaaaat tatttgattg gtgctgcagt gattagcgag caagcagacg
     5221 aattgatcga tgatttgaca ctcgtcatca atcaaaaatt gactaaaaaa gagttggata
     5281 gctatatcat ggggtatccg acattggcaa gtgatctctc ctatttattg aaataatcag
     5341 catgataact aaagcgcttg ttgctttttc cttcttgtgc tacactttaa aaaatgaata
     5401 cctgtttctg gggatgtcgt agacgacatg agagtaagtt gtgaacttag acccattgaa
     5461 cctgtcagtt aatactggtg aagggagaaa catagcagac gcttgaagcg ggttactatg
     5521 tcgtgcccat ttcaagcgtt ttttgttatt catattagaa gaaaggaggt aacaaaatga
     5581 agaaaaatct ttatccagca gtcagtatgg cattcatttt aattatttgg cagattgttg
     5641 tcatagtttg gaaaatacct gcctttattt tacccggacc tgctgctgta ttttctgcat
     5701 tagcggcaga tgcacaagta ttactttccc attctgtcac gacattaaat gaagcagtgc
     5761 ttggtttggt aatagctagc gttctttctt ttattactgc cttggcaatg gattattgga
     5821 agtttttaga aatgtctttt tatccgttac tagtgatttc acaaatgttg ccaatcatgg
     5881 tgttagggcc attacttacc ctatggtttg gtttcggtat gcttccaaaa gtgatccttg
     5941 ttgtcttgat aagctatttt ccgatcgtag tttctttttc ggatacattg aggaaagtat
     6001 caaaagagca aatcatcttt ttgaaaacga tgggggcaga tacagggaag atttatcgaa
     6061 tatataaaat accagcgggt ttatccggct tcttttccgg tttaaaagtg gctgctactt
     6121 attgtgtcag cggagcagtc gttggagaat ggctaagcgc tcaagcaggc ttagggtatt
     6181 acatgatacg cgtaaaaaac agctaccaga tcgataaagt ttttgctgcg atcatttgtg
     6241 tcattctatt gagtttattg ctgaatggcg cttgttcatt attgaaaaaa gggtattatc
     6301 gtatgcttta tattttttaa gagaagggga tcaaatgaaa aaattatggc ttttattacc
     6361 gctactgttg cttttatccg cttgtggcac tgcaaaagaa acaagtagca aacaagaaat
     6421 aaaggatttg aaaaaagtga cacttgtttt ggattatgta ccgaatacta atcatactgg
     6481 catctaccta gcaaaagaaa aaggctatta taaagaggct ggtttaaatg tccaaatcat
     6541 cgaaccagga gataattcga caagtattgg tctagtaggt gcggacaaag cacaatttgg
     6601 tgtaagttat caagaagatg tcacttatgc tcacgcagat ggacagaata taccagtcaa
     6661 agcaattgct acagtgatca aacataatac ttctggattc gccaccctat cagacagtaa
     6721 catccattca ccaaaagatt ttgaaggaaa aacatatgca ggttggcaaa gtccaagtga
     6781 agaagctgtc ttaaaagctg tgatggaaaa agacggcggg gacttttcaa aactgacaat
     6841 ggtaggaagc aatggagaag ggccagaaag cttaggaaaa tcctcagata tccaatggta
     6901 ctttgaaggt tgggatatga tcaaagcaaa agaagcgggt attgaactaa actatatccc
     6961 attgaaagaa ttagatgaac ggttagatta ctatactccg gtaattatta cgaatgatca
     7021 actgatcaaa agtgatccag aattggtaca gtcttttatg gatgccacga aaaaaggcta
     7081 tcaggaagct attaaggatc caaatgacag tgctaaactg ttgcaaaaat atgcaaaaga
     7141 aaatgatcgg acgtttttag aagaatcaca agcattcttg tcaaaaaatt atacggatga
     7201 tcctgagaat tggggattga tggaagaaaa agtttggcgc aattatacag cttttatgca
     7261 ggaaaacgga ttgatcaagc aagatgtacc ttcgcaagaa ctattcacta atcagtttat
     7321 aaaataggag tgatagatat gtcaatccaa atcagccact tgaatgtagt cattgaaaac
     7381 ctgaaaatat tagaagacat ccatttcact atccctaaag atacctttac atcgattgtc
     7441 gcgccaagcg gagccggtaa gtcaacattg ctgaaaactt taacaggagt ccagcctatg
     7501 acttctggaa cgatcaaagt agacgatcaa aaagtaactg gtctccatac agcatttagt
     7561 tatatgccgc aagaagatat gttacttcct tggctgagcg tctatcaaaa cgttacgtta
     7621 tatcaaaaaa tcaatcatct aacaatcaat gaagaacaag taagggatta tctggatatc
     7681 tttgggttaa acggctatga acattttttg ccggaacaat tatctggcgg gatgaagcag
     7741 cgaacggcct tgttacgaac aatcatgaat ccttcttctt acttgcttct tgatgaacca
     7801 tttggagcgt tagatgctat gaccagaggg cagatgcaag actggatgtt gaagctgcct
     7861 aaaaaagcaa agcggactac tttacttgtg acgcatgata tcgaagaagc aatttattta
     7921 tcagacagga ttcttgtgct ttccgcccgt ccggcacatg tgattgctga gattcaagtg
     7981 cctgaaaaac gacggtcacg tgaatggcta ctgcagcaat cagagttgaa gcaaacgatt
     8041 tatcagttat tggcaggtga attagatgtt aagtgatgct cattgtcatt tagatgggag
     8101 tcagagttta gcactccttc agcaggaaca cacgattttg acgatcatca attgtgattc
     8161 gccagaagaa tggaaggaaa acagacagct tgcagcaagt aagactcaag ccttaagtta
     8221 cggtatccat ccttggaaag cagatagcta tacgtttgaa caagttgagc cttttttgaa
     8281 aaaagcaagg atcatcggtg aaatagggtt agataatatt tggacgaatg taccgatgac
     8341 tacacaaaaa aaagtatttg agcgacagct tgcttttgca gccataaatg agaaacctgt
     8401 tgtactgcac acaaaaggat gcgaaaaaga gatcttaaat tatatccaag cttaccctaa
     8461 tcactatttg atccattggt attcttcttt ggactatcaa caagactata ttgatttagg
     8521 ctgttatttc agcattggtc ttgatttgaa aaagaatcca gcagtctggc aactagctaa
     8581 agcagtccca atcgaccact tacttattga aacggatgga ctacatgcag cagagtgggc
     8641 tttagggggg attttttcag aaaaagatta tgtctcactg cttgaagaac agttaaagac
     8701 aatcgctgag atcaaagagc tatcagttga agaagttaaa aaaaatactt atcaaaactt
     8761 ggaacgtttc attagattag gtaaataaaa aagagatgtg acacaactag tgtcgcacct
     8821 ctttttggct ttctttgtat aaaagtaaac tgtttgatta ataaatgaat cttagtacca
     8881 accgtttgct tcccagaatg ctttcgccgc ttcccaagaa ccataacgtg aagtaacata
     8941 ttgttctgct actctttctt ggtttgcagc agagtagtca ccatttaagt aagaagaatc
     9001 taattggtaa cgtccgatgt aacgtccgtt cgttgctgtg taagaaccgc ttgattcttt
     9061 ttgtgcgatc cattcttttg cagagcttgt gcttgctgga gtagcagcag tttctgttac
     9121 agcaggagca ggttgtgttt cagcaacagg cgctgcttgt ttttccgttt gaaccgtttc
     9181 ttgtacaaca ggttgttcag cttggactgg tgcttcttga acggctgctt gaggttcagc
     9241 agctgcttgt gcagagcctt ctgttgggat tgttaattgt tgtcctgagt a
//
LOCUS       DAJSMK010000090         8979 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.094, whole genome shotgun sequence.
ACCESSION   DAJSMK010000090 DAJSMK010000000
VERSION     DAJSMK010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.094"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(508..1461)
                     /gene="menA"
                     /locus_tag="ON488_002200"
     CDS             complement(508..1461)
                     /gene="menA"
                     /locus_tag="ON488_002200"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HCR3232366.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1474..2577)
                     /locus_tag="ON488_002201"
     CDS             complement(1474..2577)
                     /locus_tag="ON488_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCR3232367.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2667..3623)
                     /locus_tag="ON488_002202"
     CDS             complement(2667..3623)
                     /locus_tag="ON488_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HCR3232368.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3904..5838
                     /locus_tag="ON488_002203"
     CDS             3904..5838
                     /locus_tag="ON488_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCR3232369.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            6295..6711
                     /locus_tag="ON488_002204"
     CDS             6295..6711
                     /locus_tag="ON488_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HCR3232370.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6725..7291
                     /locus_tag="ON488_002205"
     CDS             6725..7291
                     /locus_tag="ON488_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HCR3232371.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            7314..8300
                     /locus_tag="ON488_002206"
     CDS             7314..8300
                     /locus_tag="ON488_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HCR3232372.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8455..>8979)
                     /gene="scm"
                     /locus_tag="ON488_002207"
     CDS             complement(8455..>8979)
                     /gene="scm"
                     /locus_tag="ON488_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HCR3232373.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
BASE COUNT         2662 a         1730 c         1810 g         2777 t
ORIGIN      
        1 gcaaacgagg atgttaaaag aataccatat agttaccaaa ccaagaaagt tctcgtcaag
       61 ttcgctggta cgaatcaaat caagtgaaaa aagggactgt gaaaaaaatt gtgtcatagt
      121 tagtcacttt ttccgaacaa atagtgttca atcagctgtc cttcggtatt agctcaaaaa
      181 acggcaaaat atgaggaact atttttccat ttgtttctct aatactcagg acaaaacact
      241 gattttacaa cctctgataa acggtgttca aaagccagtt tctcggtatt aagccaaatt
      301 tatgcaaaaa tgtggaaagc cattttcaca aaatttttct taatactcga aactaagcga
      361 ctttttcaca acctcctgat aaacggtgtt caaaagcttg catctgcggt aataagccca
      421 accaaacgaa aaatataagg agctattttt atttggctgt tcttattact tgatgcaggg
      481 cagttttttc acaacctctt catgctgtta aatggcttgc ataatgattg ttagtaatag
      541 ccccaataca taactggcat tgaataagac catatttttg atggaatagc tgaaactgat
      601 aggctggggt aacgtttgct tgaattgatc caaatgcttc ttcacaattg gcaaggtcaa
      661 gaaggtgacc aagatcggcc attcatagat accgctcaac aaccccatta aaatcacgaa
      721 atagcaagca tacatcaata gctggaataa gactgttccc gcaggacgtc cgatataaaa
      781 aactagtgta tagcgatgat tttcaatatc acggtcaaga tcccgcaaat tattagccaa
      841 catgatattg gcaatcgtaa acaccaaggg taaggaagct aatacgattg ctgctatagc
      901 ccaaagattt cctaccaaat caaattgtcc agatgaaaag ttgactgtca gatcatagac
      961 atctgaaccg aatgtattga cataaacgac catggcaaaa attccaaggc ccatagtcac
     1021 cccactgaaa atttccccta aaggcattcg agataaagga atcggtccga atgtatagaa
     1081 tactccaata aaacaacaga taaatcccat caaaagtaaa agccaacccg tattgatcgt
     1141 tagaataacg ccgataacaa aaacaaatgc aatcatagct aaaatcatgt ttcgaatcaa
     1201 tacaggagat agatttctgc ggccaatgac attttcttca tacttatata cttcagaatg
     1261 agccttttca taatccatgt aattattgat agcggtagtc gctaaatcaa aaactagcat
     1321 tccaataaaa aataaaaaag tgtttagcca atgtatctca tgaaaaaaag cgatagagaa
     1381 taatacccct accgcaaaag gaaatacact agccaccttt gttcgtattt caactacttc
     1441 taaaaagatt tttagtgtca tggttcgtac tccttatttt agttcagaac ggtcacccat
     1501 cgtgtaatgg gagtcctccg ataatttgaa ggtgtctttg attggatcgg tcacatatac
     1561 tttatcgtct tttgtcacga agatcgcttc cgtcccgtta ttcaattcgc tttcgacgta
     1621 ttccagtcct tttttcacac ccattgaaaa gactgctgta gacaacccgt caccatcaat
     1681 tgatttatct gttatgatcg tgacacttgc gatatcattg tcgaacggat aacccgtttt
     1741 tggatcaaac aaatgatggt attttttgcc atctacttct aaataacgct cgtaaattcc
     1801 agaggtaact aatgttttgt tccgttcttt aatagaacct aaaacagatc cgcgagccat
     1861 gttcggatct tggatgccga ctgtccagtc ttggttttcg cctcttgggc tgtggcctaa
     1921 gacatagaca ttaccgccca agtcaacgat ggcagtggtc actccttgtt ttttcaagac
     1981 tttcactact tcgtccgtaa tgtaaccttt ggcgattgca cctaaatcga tgatcattcc
     2041 tttttctttt agataaacag ttttttcttt gtcatttagt tcgatcttat gataatccac
     2101 taatttcaat gcctgatcga tttcttcttg ggaaggtttt ctggcgtcat caaaaccgat
     2161 tcgccataat tgtgtgattg caccaatcgc catatcgaat ccgccttgag aatcttggct
     2221 atattcgtag gcccgcttga ctaacgtgta gacgtcatca gaaactttta ctggtttgat
     2281 cccagcttgc tcattcactt catcgatctc agaacctttt tgattgatcg tgattttatc
     2341 accaagttct tttactcgat cgaaggcagg tttcaatgct gattctttgc cttcatcata
     2401 cacacggata cgaacgtaag tccctaacaa gaactgttca tcagaatatg gatctttcaa
     2461 tatcttggta gctgctgaac tttcagtggt tgttttattt gctgagttgc tgcagccagt
     2521 tagcaccata aaagagatgc ccagtgtgat taaggaaaat agtagttttt tccgcatctt
     2581 tttcctctct tcattttgaa aggtgagacg actgcctaat ctggctatcg tcccaccctc
     2641 caacttttat tagtatgatt atgtgattat ttttctgtta cgatattatc tacttcgatt
     2701 gtttgagtgt cgcctttttc agctgcattc actaattgtt gtgcgtacat gatgaatgaa
     2761 tgtgagctgt gtgtagcacc tgtaacaact tctacattag caggtgagcc atcttcttcg
     2821 cccattgctt tgacgaattc gtcgttcaga gtagggatgt aagtttttgg ttctgtaccg
     2881 ctttttgctt tcatattttc attatattct gtatcatctt gttttgattt accgtctttg
     2941 tcgatataat caaagtttga ttcagttact ttgccgccag caactgtcat ttcgaattgc
     3001 acacggtagc cgttagagta gttcttttct tcaagcttgt aagtgccgtc tttcaaatca
     3061 gcaccattgt cgatttcgat tgtatctgtg ttaccagctt gagcagcttg gatcaattgt
     3121 tgtgcgtagt tttggaagct ttcagatgag tgagtagctc cagttacgac ttccacaccg
     3181 cttgcgcttt gtgcttttaa gaattggtca ttcaactcag gaatgtattt ttctgggttt
     3241 gtgccagatt ttgcttccat gtttttgttg tattctgcat cttttgtttt tgattcgccg
     3301 ttttcattga cgttatcata ttttgattca gtgattttgc cgtcttttac aaccatttca
     3361 aagactgcac ggtaaccatt tgaataattt ttttcttcta atttatatgt gccgtcttgc
     3421 aaatctccgc cagctacaac ttttgcagat gattctgttg tgctttttgc agtcgaagat
     3481 tgtgctgtag atgattcaga agaagagttt gagcttccgt tgtcatctgc gccgcaagcg
     3541 cctaacacta gagctgaaaa tgctaatacg gcaaatccag ttacaaaacg ttttttcttc
     3601 attttaatac cccaccattc catttctagt ccacaatttt tctttgtgat tcattataca
     3661 ttctaatctt tttagcctat aagtcaacta tttttgataa ataacccatg taatatttca
     3721 aacgttttct ttcagcaaat ttcgtgaaaa aacgctttat tttaaaattt gaaaaaaatc
     3781 caaaaggagt tagacaaaag aacagaacat ctatataata tatggagatt gtgtaataag
     3841 tatcaaacta aaagaattat catatattca ttatatagat agtctataag gagcggatga
     3901 tcaatggcaa agcaaaatat tgtcgttgta ggagcaggat atgccggtgt ttcagctaca
     3961 aaatacttgg caaagaaact gaaaaaagaa gatgtagcaa ttactctgat cgatcgtcat
     4021 tcgtaccata ctatgatgac cgagttgcat gaagtagctg gcggacgtgt agaaccagaa
     4081 gcaatccaat acgatctgca gcatttgttt gctcgtcaaa agaatgtaca acttgtcaca
     4141 gacactgtaa tcggtatcga taaagaacga aaaatcgtca agaccaaatt aggttcctat
     4201 ccttttgatc agctgatcct tggaatgggc ggagagccga atgactttgg tacacctggt
     4261 gtcaaagcac acggattcac cctttggtca tttgaagatt ctgtaaggat tcgggaacat
     4321 attgagaaga cagtagcaaa agctgcattg gaaccagatg atgaactgcg taaagccatg
     4381 ctgactttcg ttgtctgtgg ttctggattt accggtattg aaatgattgg ggaactgatc
     4441 gactggaaaa atcgcctagc caaagattat aaattagatc caaacgaaat cacactgatg
     4501 gtcgtagagg caatgccgac gatcttgaat atgttggatc gaaatgatgc tgcaaaagct
     4561 gaacgctatt tgcgtaagca caacgtggaa ttattattga atgcaccaat cgtagaagtg
     4621 gctgctgatc atatcaaatt gaaagacgga cgcaacattc cgactcacac actgatttgg
     4681 acagctggtg tcaaaggaac ttctgacgct gctgactttg gattagaatc agcacgcgga
     4741 cagcggttga tcgccaatga atatatgcag gcaaaaggct acgaagataa aaacatctat
     4801 atcattggtg atttagtctt ttatgaagaa ttcccaggaa caccgacacc gcagatcgtt
     4861 caagctgctg aacaaacagg acacacagcc gcagcgaata tcgtggcttc gatcaaaggc
     4921 ggagaaaagc ataaatttaa aggaaactat caaggattta tggtttctat tggtgccaaa
     4981 tggggggtag ctaacctatt tgataagatc catttaagcg gatttttagc tatcgtaatg
     5041 aaacatatcg tgaatttgaa atacttcttt gatattcgtt ctggttatta tatgttccaa
     5101 tatttaatgc atgagttttt ccatatcaaa gatgatcgca acgtgactcg aggacattct
     5161 tctcgttacg gcaatgtctt atggagtgtg ccacttcgta ttttctatgg tttagtttgg
     5221 ttcgttgaag cttccaaaaa aatcattggg aatggtgaag tgttcaaacc aagtacttgg
     5281 tttggtgaag gatcatggtt cactggaaac agtgtgttcc cttggacatg ggaatacaat
     5341 gtaacagatg ttgccagtgg tgcttctgct gctggtgatg caaccacagc tgccagcgga
     5401 gcaggggcaa gtgccggaga agcagcgact caagctgcac attttggttt gagttatgca
     5461 tacggtgaag aaccaatggc tgtgattgag aagtcaccag actggttcac aaagatcatg
     5521 caagtgatca tgccaaacaa tgatgtagca atgttcttcc aaaaattcat ggtattcttt
     5581 gaaattgcct tggcattagc attgattgct ggattattca catggctatg cagtgcgaca
     5641 acgattgtat tggtgatcac gttctgctta tcaggcatgt tttactgggt aaacatttgg
     5701 ttcatttttg ttgctttcgc attgatgaac ggttccggac gtgcgattgg gttggatcgc
     5761 tgggtaattc catggctaca acgtacacta ggtaattggt ggtacggtag accaagttcc
     5821 cagtacggca agaaataaat agataaagaa cgttatttga atgcaagatt tcaatagaaa
     5881 ggggctgaga caaaccgtca cagcctcctt tttatgtaaa attaaaggaa taagatgccc
     5941 gagataagcc tccatgagca agacacaggt gtcacaacct ctgttacaac ctcttgttat
     6001 aaacggtgtt ccagaagtag cttcttcgaa aaataagccg aaatttcaca aaaacttgaa
     6061 aagtaatttt cgtaaattcc ttcttatttc ttgaagttgc ccacttctgt cacaacctct
     6121 tgttataaac ggtgttccac ctgctgcttc tcggtaataa gcccaaagaa ttagaaaaca
     6181 tggaaagctg ttttctattc ttcgttctta ttactcaaag caagacacag gtgtcacaac
     6241 ctcttgtttt tatgctaaaa ttgggtgagt taatctggaa aaaggagaac aaaaatgagc
     6301 cttaaagaat ttgctgaaaa aagtctgctc aaaccttggg atgtttttat tattttgctt
     6361 ttgactgttc tttctttttt accagtcatg atttttggtc ttcagcaaaa caccgcaaca
     6421 gcagaaaaag aagcggtact gcgtgtggat ggcacagaaa tcaaaacatt ccctttgatg
     6481 gctggagaag agagcaacac atatacttac aaagatgaac acggagatta taacttgatc
     6541 gagatagatg gcgatcgagt acggataaaa gaagcagatt gcgatgacca gatctgcgta
     6601 cgtcgaggct gggcaacgaa aaatggcgaa accatcgtct gtttgccaca taaattagtg
     6661 atcgaagtcc gttcaacaga tggaggtgac gaagacagtc tgatttatta gaccttcaca
     6721 caccatgagt aaattacaaa aaatgattta tatttcgcta cttgttgcac aaggagtgat
     6781 cattggttta ttggaaaata tgatccctta tcctttttct tttgcgcctg gtgcaaaact
     6841 aggcttagcc aatctaatca cgatcgttgc catttttacc atgaaaaaac aagacagctt
     6901 cttactactt tggctacgac tattcctgac tactttgcta ggcggaacga tttccacatt
     6961 cctttatagt atgagtggtg ctttgcttag ttattttgga atgttattgg tcaagcaatt
     7021 aggaccaaaa cgtgtcagta tcatcggaat tagtgcggcc ggcggtttca tgcataatgt
     7081 cggacagctt ttgatggctt ctttcattgc acaatcatgg acagtcatgt tgtacttgcc
     7141 agtcctttca gttttaggga ttttatcagg gattgcaatc gggatcgcag cgaattatct
     7201 tttacgacat gtgcagacac ttcaacgatt ccaaaaagat tatgagcagg gaaccaaaca
     7261 aaaatggagc ccaatgttta ccaaaaaata atcgtcacac aaggagtttt tttatgaagc
     7321 tacatccaat gtgggaaaac tatcctgctt taagtaaaga attgacagaa acactaaaac
     7381 ggatggaaga aactgtccgc ctgaaaaaca aacctgtcga acaagccatc aaagaaacga
     7441 tccatgccgg cggaaagctg ttgcgtcctg cctatcagct attgttctca caatttggac
     7501 cagagcaaga tcgagacaaa gccatcgctt tggcagcttc tatcgaaatg ctccatacgg
     7561 ccacactgat ccatgatgat atcgttgatg aagcggatct gcgacgtggt cagcctaata
     7621 tccgtagtca gtttggtaat gtcgtttctg tctatgcagg agactattta tttgtctgct
     7681 gttttaaact attgtctgat tactccactt ccttgaaaag tctccaattg aattctcgca
     7741 gtatggaaaa agtattgaat ggcgaattag ggcagatgga tgatcgctat aattatgaac
     7801 tttctgtaaa agaatatttg gaaaatattt caggtaagac agctgaactg ttccaattaa
     7861 gttgttctgt tggcgctttt gaaagtggaa caagcgagcg cttcgcaaaa aaagcaggag
     7921 atatcggact ttctatcggg atggcctttc agattatcga tgatatttta gattatacaa
     7981 aagagagcca ggaaatcggc aaacctgtac tagaagacat gcgtcaaggg gtctattctt
     8041 taccgttgat ctactctttg caaaaaaaca aaccaaagct actaccttat ttagagaaga
     8101 aagcggcaat gacagaagaa gatgtcgacg ccgtacgcaa aatcgttgaa catacaggag
     8161 gcgtggaaga agctaggaag ttagcggcct cttacacaga aaaggctttg aaggaaataa
     8221 agaaattacc tgccacctct cttcgaacaa aagagaatct cttttccctt acccaactga
     8281 ttttggatcg caaagactga atagggaaag gttcgatacg taaataaatt tctcagaagg
     8341 aaatctacgt gttttttgac aaattgaatt gtagttcttg tatttatgat aaaaagcaaa
     8401 aataaagagc aacgtccgtt agcgacgttg ctctttttta tcttgaatat ttttttacct
     8461 tttcgatttc ttataactca taaaagtgat tcttaaaccg attacaagta atataacgcc
     8521 tgcgagtgtt atccaattat tcgattgact tccagtttta ggaagtgctc tttttgattt
     8581 gtttccattg tcattgcttg ttttattagt taagttaaag ttcgtcctgt tatccgaact
     8641 tgtttttgag aaggagacac ttgcatgacg tgtatcgctt gtggtagacg acgtgtctgt
     8701 actatcgctt gaagttgatg aatctgagct atcacttgtg gtagaggatg tatctgtact
     8761 gtcacttgaa gctgacgtgt ccgtgctatc acttgtagtg gtagatgaat ctgagctatc
     8821 acttgtggta gaggtagtat ctgtactgtc acttgaagct gacgtgtccg tgctatcact
     8881 tgttgtggta gatgtatccg tactgtcgct tgaagctgac gtgtccgtgc tatcacttgt
     8941 ggtagaggta gtatctgtac tgtcacttga agctgatgt
//
LOCUS       DAJSMK010000091         8598 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.095, whole genome shotgun sequence.
ACCESSION   DAJSMK010000091 DAJSMK010000000
VERSION     DAJSMK010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.095"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..132
                     /locus_tag="ON488_002208"
     CDS             <1..132
                     /locus_tag="ON488_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3232374.1"
                     /translation="RRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            230..862
                     /locus_tag="ON488_002209"
     CDS             230..862
                     /locus_tag="ON488_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HCR3232375.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(864..1769)
                     /locus_tag="ON488_002210"
     CDS             complement(864..1769)
                     /locus_tag="ON488_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HCR3232376.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(1854..2513)
                     /locus_tag="ON488_002211"
     CDS             complement(1854..2513)
                     /locus_tag="ON488_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HCR3232377.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     CVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVS
                     I"
     gene            2829..3773
                     /gene="mvk"
                     /locus_tag="ON488_002212"
     CDS             2829..3773
                     /gene="mvk"
                     /locus_tag="ON488_002212"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HCR3232378.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3766..4743
                     /gene="mvaD"
                     /locus_tag="ON488_002213"
     CDS             3766..4743
                     /gene="mvaD"
                     /locus_tag="ON488_002213"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HCR3232379.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4756..5841
                     /locus_tag="ON488_002214"
     CDS             4756..5841
                     /locus_tag="ON488_002214"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HCR3232380.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5838..6902
                     /locus_tag="ON488_002215"
     CDS             5838..6902
                     /locus_tag="ON488_002215"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HCR3232381.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(7151..7954)
                     /locus_tag="ON488_002216"
     CDS             complement(7151..7954)
                     /locus_tag="ON488_002216"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HCR3232382.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7974..8279)
                     /gene="kduI"
                     /locus_tag="ON488_002217"
                     /pseudo
     CDS             complement(7974..8279)
                     /gene="kduI"
                     /locus_tag="ON488_002217"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(8261..8467)
                     /locus_tag="ON488_002218"
     CDS             complement(8261..8467)
                     /locus_tag="ON488_002218"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HCR3232383.1"
                     /translation="MLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLIVIIIGG
                     ILTGIFTAVEASAIAVIYKWVIRF"
     gene            complement(8511..>8598)
                     /locus_tag="ON488_002219"
     CDS             complement(8511..>8598)
                     /locus_tag="ON488_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCR3232384.1"
                     /translation="YIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT         2605 a         1795 c         1673 g         2525 t
ORIGIN      
        1 cgcagaagag aaaagattat tcgcatcttc cccaatcaaa catcagccaa tcgcttaatt
       61 ggagccgttc ttatggacct gcatgatgaa tggatttatt cttcaagaaa atacatcaat
      121 tttgataagt agaaatggta aaaacattgt atagcatttt acacaggagt ctggacttga
      181 cttgattccc gcttctttgc tatactaaag aaaaacgagg tgaacccaca tgaaaaaaat
      241 cgaacctatt ccaccttctc ttcctcttct tacaaaggga gagttttatt tagaagatga
      301 ggagatcttc tctggtcttc tgatcaacgg aggtaaccaa agctatctcg atgccaaaaa
      361 tatggtatta agagagagtc atatccaaaa acttacgatg caaaaaacag gtttacgtca
      421 ttttgaatgc agtaatgtca tttttgaaaa atgtgatttt tccaatctgg agtggattgg
      481 tggcagtttc caccaagtcg tgtttcatca atgtaaatta acaggtacga attttgccga
      541 aagttatctt cgagactgta ctttcactga ttgtattgct tcgatggctt cctttagtag
      601 tacaaacttg aaagctgtct ccttcgatca ttgtcaatta gaagacagcg aattttatga
      661 ggtcacttgg aaaaaccttt ttttgtctga caatcagtta accggttcga actggtttcg
      721 aacttctctg aagggattag actttacgac taatttcttc acaacaatcg ctttatctca
      781 agattctttg gcgggactaa tcgtcaatca agagcaagca cttgtgatcg cccaagccct
      841 tggtttgcag atcaaagact agatcaacga atccgccgcc acagtgcaat aagcatccaa
      901 atagataaga ccaaactgat gatcaaggcg atttcccatc cgaaaacgga atgggtaaag
      961 ggtaactgga gattcattcc gaagaatcct gtcacaatag ttggaacggt caagatcagc
     1021 gaccagaccg tcaaaaattt catcgtgtca ttcaagttgt tattcagcaa attattataa
     1081 gtgccagaga gctggtctaa aatctgcgaa gctaagttcg tcatttcaac tgcttgtcgt
     1141 gcttcgatca gtgcatcgtc caactcttct ttttcctttt ctgacaactt gcgataaata
     1201 gccagtgcct tgatttgttc taaaagtact acattttgtt ttgttcctgt aactaagtaa
     1261 accaaaccga tctctaaatc tgaaagttgc agcagattct tgttcgttgt tttttctctt
     1321 aatttcagat taagccgctg acgttcacta ttcacttcct cgattaaagg aaaaaaggaa
     1381 tcagaaatca aaaacaatgt acgaaacaat aaactgtata cactcatgtc tggcatccgt
     1441 tccaaaagcg atcgaattag tcgaatcacg tactcggtat tcggcgtggt aaatgtaaac
     1501 aaaccgtctt cttttaaaat aaaagcgata ggactagttt cataatgatt atcgactttt
     1561 tgctggtgcg gaacatttga tacaagcagt aacgcttcat caaaagaatc gtactctacg
     1621 cgcgcccgtt catttttatc tagagaataa gtcagcatct cgtcactaat gccatattct
     1681 tcttttaagt ttttaacagc tagcacatcg ttttgctgta cattgatcca aaaattacgg
     1741 tcttgattaa aatagtgttt ttcccgcata ctctatcctc ctgacatttg tttccagtat
     1801 aaagaaaaaa gtcgctcaaa taaaggttta ccctttattt gagcaactgt aaatcaaatg
     1861 gatactttgg tttggcgaat ctctgctaat ttttcttcga tcattttcaa gacttcttct
     1921 tttgcttgag gatcttccac aaaattatag cggtctccat cgatttggat ttttggactt
     1981 tctttgtatt cttcatacca ttgatcataa cgtctgttca attctttgta ataatcgtat
     2041 agacttgggt caaaggacaa ttgttcatac gaacgaccac gtttttcgat acgctctaac
     2101 atcgtatcaa aagatacacg aatatgaact aataaatccg gatgtttttt atgggcagca
     2161 tagggaagtt cttccatcat gttttccagc agttcatcat acacacaaac ttctgtttct
     2221 gttgctcttc ctagatctgc atttagatgg aaaagcagtg aatcttcata aatcgaacgg
     2281 tccaatacat tattgtcatc tttcattgct tgtttgatgc ttgcaaaacg tttattcaaa
     2341 aaataaattt gcagcaaaaa agcatactgt tcagggtttg cataaaataa gggcaagact
     2401 tcattatcat caatcgattc ataaaatgcc tgactatcaa agtgttcagc catcatttct
     2461 gttaaacttg attttccggc accaattgta cctgctaaaa cgatcacgct catttacctc
     2521 cagctcactt catcactaaa tattgtgttt aactccaacc ttttttaaat atacccccaa
     2581 tatctagtag tgtcaattgt attttttcta gtcaaagaag aaaaaaagtc aaaaaattct
     2641 taagaaaaaa gtgttttttc tttagaaaac gtattcttag ttttacttct gagatggttt
     2701 tagtaaaata aaggaggaat gttttttgag acccttagtg gacaaaaaaa ttcgtgaagc
     2761 agcgcaactc gttttgggcg ctttattttt tgcttaaaaa tcacttttac gtgagaagga
     2821 gttagattat ggcaaactat ggccaaggag aatcaagcgg aaagatcata ttgatgggcg
     2881 agcacgcggt tgtttatgga gaaccagcga ttgcctttcc tttctatgca acaaaagtca
     2941 ccgcattcct tgaagagctg gatgcaatgg acgatcaact ggtttcttcc tactattcag
     3001 gaaatttagc cgaagctcct catgcattaa aaaatatcaa aaaattattc attcacttaa
     3061 aaaaacagca tgacatccaa aaaaacttgc aactgaccat tgaaagcacg attcctgctg
     3121 aacgtggaat gggatcaagc gctgcagtcg ccacagcagt cactcgtgct ttttatgatt
     3181 acttagcatt tcctttgtct cgtgaaatac tattagaaaa tgtccagctt tcggaaaaaa
     3241 tcgcccacgg taatcctagt ggaatcgatg cagccgctac tagcagcttg cagccgattt
     3301 attttacaaa agggcatcct tttgactact tttctttgaa catcgatgct tttttgattg
     3361 tcgctgatac aggaatcaaa ggacaaacaa gagaagccgt caaagatgtc gctcacctct
     3421 ttgaaaccca gcctcatgaa actggacaaa tgatccaaaa attaggatac ttgacgaagc
     3481 aagcaaaaca agcaatcatt gagaattcac cagaaacgtt ggcacagaca atggatgaat
     3541 cacagtcact tctggaaaag ctgacaatca gcaatgattt tcttaatcta ttgatccaaa
     3601 cagcaaaaga taccggggca ttgggtgcca aattaactgg cggtggacgc ggtggctgta
     3661 tgattgcatt agcacaaaca aaaacaaaag cccaagaaat cagtcaagca cttgaagatg
     3721 cgggtgctgc tgaaacttgg atacaaggat taggagtaca tacctatgtt taaaggcaaa
     3781 gcacgcgcat ataccaacat tgctctaatc aaatattggg gtaagaaaaa tgaagaactc
     3841 atccttccaa tgaacaacag cctttcgtta acattggatg cattttatac agagacagaa
     3901 gtcatctttt ctgatagcta tatggtagat gaattttatc tagatggcac cttacaagac
     3961 gaaaaagcaa caaaaaaagt cagtcagttt cttgaccttt ttcgtaaaga agccggcctc
     4021 tcactaaaag cttcagtaat cagtcagaat ttcgttccta ccgcagctgg attagcctcc
     4081 tctgccagcg ggctagctgc tttagcagga gcttgcaata ctgctcttaa gcttggatta
     4141 gacgatctct ctctttcaag atttgctcga cgcgggtctg gttcagcttg ccgaagtatt
     4201 ttcggtggtt tcgttgaatg ggaaaaaggc catgacgact taagttctta cgctaagcca
     4261 gtcccttccg attctttcga agacgattta gcaatggttt tcgttttgat caacgaccag
     4321 aaaaaagaag tgtccagcag aaatgggatg cgtcgaacag tcgaaacatc cagtttttat
     4381 caaggctggt tagattccgt tgaaggggat ctatatcaat tgaaacaagc aatcaaaaca
     4441 aaagatttcc aacttctcgg agaaacgatg gaaagaaacg gactaaaaat gcatggaacg
     4501 actttagctg cccagcctcc attcacttac tggtctcctg acagcttaaa agcgatggat
     4561 gcggtgcggc aattgagaaa aaaaggcatt ccatgctact ttacgatgga tgctggccct
     4621 aatgtcaaag ttttagtgga aaacagccat ttatctgagg tacaagaaac atttaccaaa
     4681 ttatttagca aagaacaagt aattactgcc catgctggtc caggaattgc gattattgaa
     4741 taaagggaga tttttatgat tgaagtatct gcaccaggca aactctatat tgccggagaa
     4801 tatgcagttg ttgaaacagg acatccagca gttatcgctg cagtcgatca attcgtaaca
     4861 gtcactgtag aatccgcacg aaaagtcgga agtatccaat ctgcacaata tagtgggatg
     4921 cctgtacgtt ggacaagacg caacggagaa ttagttttag atattcggga aaatcctttt
     4981 cattatatcc ttgctgctat tcgtttgact gaaaagtatg cacaagaaaa aaacattctt
     5041 ttatcctttt atgatctgaa agtaacaagt gagttagaca gttcaaatgg ccggaaatat
     5101 ggattgggtt ctagcggtgc cgtgaccgtt gcaacggtca aagccttgaa tgttttttac
     5161 gcgttgaatt tatctcaatt ggagattttc aagattgcag cactagccaa tttagcagtt
     5221 caagataatg gttcctgcgg cgacatcgct gctagctgtt atggtggctg gatcgctttc
     5281 tcaaccttcg accatccttg gctccaagaa caagaaactc agcattctat cagtgagtta
     5341 cttgccctgg attggccagg tctatccatt gagccattga ttgctcctga agatttacgt
     5401 ttattgattg gttggacggg tagccctgcc tctacttctg atttggtcga tcaagttcac
     5461 cgttcgagag aagacaaaat ggtggcttat cagcttttct taaaaaacag tacagaatgt
     5521 gtcaacgaaa tgatcaaagg gtttaaagaa aataatgtaa cgttgatcca acagatgatt
     5581 cgaaaaaacc gacaattact gcatgattta tctgcaatca ctggggtcgt catcgaaacg
     5641 cctgctttga acaaattgtg taatttagct gaacagtatg aaggagccgc aaaatcttct
     5701 ggtgcaggtg gtggcgattg cggaatcgta attgttgacc agaaatctgg catccttcct
     5761 ttaatgagtg catgggaaaa agcagaaatc actccactgc cgttacatgt ctatagcgat
     5821 caaagaaagg aaaaccgatg aatcgaaaag acgaacatgt ttcactagct aaagcctttc
     5881 atgataaaca aaaaaacgaa tttgacttcg tacggatcat ccataaccct ttgccgcaaa
     5941 tagcagtttc tgatgtcgat ctaagtacac aggcagttgg gtttacacta agcagcccat
     6001 tttatatcaa tgcgatgact ggcggaagcg aaaaaacaaa aaaaatcaac caagatcttg
     6061 caatcgtcgc aagagaagca gatttgatga ttgccactgg ttcagtcagc gctgccttga
     6121 aagacccttc tttagccgat acttatacga ttatgcgaca agaatatcct cacgggaaaa
     6181 tcattgccaa catcggtgca gggacttctg tcgaaagagc ccaagaagct atccgattgt
     6241 ttcacgcaga tgccttacag attcatttga atgcacctca agagttggtt atgcctgagg
     6301 gagaccgtga ttttaccaat tggaaagtac ttattcaaga gactcaaaca gccattgacg
     6361 tccccctcat cgtaaaagaa gtcggttttg gcatgacaag agaaacgctc aatgatctag
     6421 ctgctttagg agttcataca gttgatatca gcggtcgaag cggaacaagc ttcacccaga
     6481 tcgaaaacgc ccgtcgctcc aagcgggaac tgagttattt agctgactgg gggcaatcga
     6541 cagtctcttc attgcttgaa gcaaatgaag cagacacttc tatggaaatc ctagcctccg
     6601 gaggtatccg caatgcctat gacatattta aagccctttg tctcggcgca aatgcagtgg
     6661 gtacttcagg aaccgtactg acgcatctga tgaatcacgg cgtagaagaa actattatac
     6721 tgatgaagca atggcaagaa gagcttcgtc tgctttatac tatggtcggc gcaacgaata
     6781 ccgcggccct acaccaacaa tcactgatct tttccggacc agtgaaggat tggtgcgaag
     6841 caagagggat cgacttagtg aagtatggaa gacgcacaga aaagagcgtg ggacaaaagt
     6901 aaagaacact tttatcccac gctctaaaca cgtataaacg gcggaagcaa aagcaactcc
     6961 ttcggaaata agctgaaatt cacaaaaatt tgaaaagcaa ttttcgtgaa ttccttctta
     7021 tttcttggag ttaaacgctt ctgtcccagc ctcttttttc gaataaatga tgtttaatca
     7081 gctgtccttc ggtattcgtt caagccgctg atttcacaac ctctccacta aacggtgtac
     7141 taaagctctt ttaaggttgt tttccgatat aggcaagtat gcctccgtcc acatacaaga
     7201 catggccgtt aacgaaatca gatgcgctag aagccaagaa gacagatggt ccagccaaat
     7261 cgattggctc gccccagcgt gctgctggcg tacgtccaac gataaattga tcgaatggat
     7321 gacgttcacc gttttcttgt gtttcgcgta atggagcagt ttgcggtgta gcaatataac
     7381 ctggtccaat tccattacat tggatattgt attgaccgta ttcagaagcg atgtttttcg
     7441 tcagcatttt taatccgcct tttgccgcag cataagcact gaccgtttcg cgtcctaatt
     7501 cactcatcat ggagcagata ttgatgattt taccgccgcc tttttcgatc atatcccgaa
     7561 taactgcttt tgaaacgatg aatggggcat ttaaatccac gtcgattact tggcggaagt
     7621 ctgccgcatc catttcgatc atcggtgtcc gtttgatgat ccctgcattg ttgactagaa
     7681 tatcaactga acctacatct tctttgatct gttgaaccat cgcttgaacc gcttcttcat
     7741 cggtcacatc gcagacataa ccttttgcat cgatgcctgc ttctttataa tgcgctatac
     7801 cttcatcaac tgattcttga ttcaagttat taaatacgat ttttgctcct gctgtagcta
     7861 aagagcgtgc aatctcaaat ccaataccat agacagcacc ggtgactaat gctacttttc
     7921 catctaaacg aaacatatcc atactaaatt ccatcatttt ctctccctta tgcttatttt
     7981 aattgatcca tttgcaccat atccatgtct gtataggtga tattttctcc gcacattgcc
     8041 cagatgaatg agtaattgct tgtacctaca cctgaatgga tcgaccagct tggcgaaata
     8101 atggcttgtt cattgtctac gactaaatgt tttgtttcat ctggtttgcc catcatatgg
     8161 aacacacgtg tatcttcatt ggcataatca aaatagacat aagcttccat acgacgttca
     8221 tgtgtatgac aaggcatcgt attccaagca cttcctggtt ctaaaatcgt ataacccatt
     8281 tataaatgac agctatcgct gaagcttcta ctgctgtaaa tatccccgtc aagataccac
     8341 cgataatgat gacaatcaat agaaggctag gaatcgcctc ttttattatt tttccagcat
     8401 gagccatctg tcctttttcg acaacagggt atttattctt tttagcaacg atgaatgcta
     8461 ctagcatgat tcctagcgcc cacaaagtga actgaacccc aaaagttgaa ctatttaatg
     8521 gactgtttcc gatattctac tggagatagt ccatttaact ttagttttat ccttttgtta
     8581 ttataccacc taatatac
//
LOCUS       DAJSMK010000092         8566 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.096, whole genome shotgun sequence.
ACCESSION   DAJSMK010000092 DAJSMK010000000
VERSION     DAJSMK010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.096"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(257..934)
                     /gene="nth"
                     /locus_tag="ON488_002220"
     CDS             complement(257..934)
                     /gene="nth"
                     /locus_tag="ON488_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HCR3232385.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(941..1639)
                     /locus_tag="ON488_002221"
     CDS             complement(941..1639)
                     /locus_tag="ON488_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HCR3232386.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            1907..3091
                     /locus_tag="ON488_002222"
     CDS             1907..3091
                     /locus_tag="ON488_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HCR3232387.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3097..3540)
                     /locus_tag="ON488_002223"
     CDS             complement(3097..3540)
                     /locus_tag="ON488_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3232388.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(3766..4053)
                     /locus_tag="ON488_002224"
     CDS             complement(3766..4053)
                     /locus_tag="ON488_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232389.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4224..5576)
                     /locus_tag="ON488_002225"
     CDS             complement(4224..5576)
                     /locus_tag="ON488_002225"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HCR3232390.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            complement(5849..6295)
                     /locus_tag="ON488_002226"
     CDS             complement(5849..6295)
                     /locus_tag="ON488_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HCR3232391.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(6531..7457)
                     /gene="cysK"
                     /locus_tag="ON488_002227"
     CDS             complement(6531..7457)
                     /gene="cysK"
                     /locus_tag="ON488_002227"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HCR3232392.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(7597..8484)
                     /locus_tag="ON488_002228"
     CDS             complement(7597..8484)
                     /locus_tag="ON488_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HCR3232393.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT         2332 a         1757 c         1422 g         3055 t
ORIGIN      
        1 acgtcactta tttatataat cctttggaat actggactta ttttataggt atattggaag
       61 gcattatttt ctacatcggg tattttccca ataaaaataa caacttttat ttttatcgca
      121 ataaattgta ataagttacc atcctagcta ctgagtatgt acatttactt tttcatgcaa
      181 aaaagataaa cgaaacagct tttctccata ataacaagat aattcataca tttatttgca
      241 attaaagaaa ccacgtctac aggcgtggtt tcttttttag cgccttttct tttagacgca
      301 tccgattttt cccatcttga catattgata gcaaaggaca tacctcgcac ttgggatttc
      361 ttgccgtgca atgatatcta ccaaaaaaaa tcagtgtatg atgtgtcttt acccataatt
      421 cttgtggtac tttccgcatc agtgtttctt ctacttccat gaccgtagca tctagtttgc
      481 agatcctcag gcgttttgag acacgttcca cgtgggtatc tactgcgatt gctggtatcc
      541 cgaatgcatc ccccaatacg acatttgctg tctttctgcc tacaccagga agagacatca
      601 attcttctct tgacgttggc acttgcccat cgaaacgttc aatcagctgc tgtgcacacg
      661 ctttgatgtt ttttgcttta tttcgataca aaccaatcgt ttttatttta agaatgattt
      721 catcgattga agcttctgct aacgcatcgg gtgtcggaaa agaggcaaac aaatctggcg
      781 ttgctttatt cactgataca tctgtcgcct gggcacttaa gatcactgca atcaataact
      841 caaatggatt attgtgcttg agttctccat gtgcttcggg aaacattcca tacatcgttt
      901 ctagagcttc cattgttttt tgtttgctta acatattccg ctactcctcc aaccaatttt
      961 tcagtgagac tttcggcaat tcttcttgtt gagctgactg ttctacttct ctttgaagaa
     1021 gctgctgttt tcttcgtttt tggtcttctt ccacttgttg ttttgtacgt agattttttc
     1081 tttcccacga tagcaaaatg cggtcaacgt aattaaaact ataagcctga tttaatacgg
     1141 cttcccgcag tgctagcttc aaaatttccg gctgataatg gtcttcttct agccattgtc
     1201 cgatccgctg gaactcgatc gaagaaagcg ggcgtccaaa ttcttgttca aataattgat
     1261 acactgactg gatttctttt tcttgtgttt tttcttcgta ttttttttct tgtgttttta
     1321 aatactcacc taatagatca tagatggggt aaagattata tcgatctgct tttttaccgt
     1381 tgacaatcgt cgtttctatc ttgataaatc catttgttac gagacgatcc agtatttgaa
     1441 aaatctgatc ttgtttgatt cccatatcca tagcaatcat ctgcaaatca gggaaagtat
     1501 ctccttcaag ctgtgccata tgcaactgta gaacaaataa aaattcttca gattgtagac
     1561 cgatcctatg ataattttta agtaaaagat tagatatgac tgtttgtcca gcgcttaagt
     1621 aattttctaa attcaacatg atttctcctc cgctcaatca cagtatacgt aaaaaaaaca
     1681 tgggaagcaa gaacaggttt cttttctatt tacttcactg atcggtcaga tttacaatgt
     1741 cgtctacttg atttttgttt gttcatgttt ttgatgcgta tcttcacttt tcggaataaa
     1801 taaattaagt agatttcgct gttccttaga atgttgacaa ggaaacaaaa ttactataca
     1861 ctatttttgt ttccaagtta acattattgc ataaaggagt ttttacatgt acagtttcac
     1921 aaataaacat tctaaagttt ttggatacgt ctctgtctta ttcactggat taggatttac
     1981 tatcgtcagt cctgtacttc cgtttttaac gctgccttat tctcactcca tacatcagca
     2041 agctttctat atcactttgc tcatgtctgt ttatgctcta gctgccttct tatctgcccc
     2101 cattctcggt agcttaagtg atcattttgg gcgtcatccg atccttatta tcagtttatt
     2161 aggatcaagt atcggatatt tgctttttgg tttaggaaat tcgatatgga tgttgttcct
     2221 tggtcgtatc attgaaggat tgacggcagg agaaatctcc accttatatg cttactttgc
     2281 cgacatcacg gaacctaatg aaagaaccaa agtttttgga tggatgggtg ctttagtcgg
     2341 tataggaaca acgctgggtc ctattatagg gggtctatta gctgagttgg ggaattctgt
     2401 tcctatattt attggagcac tctttacttt cttaaatgcc gtttatggct acacatttat
     2461 gctagaaagc cttccaataa aaaaacgttc agtagattta agtttctccc atgtaagacc
     2521 ttttcaccaa ttacaacaat tattcaagat ttcatccgtt attcctttat tgacagcagg
     2581 ttttgctgtt tggttggcag ctggctctct tcaatctatc ttttctcaat tttcgattga
     2641 cgcctttcag tggaaggctg ggttggttgg tttaagcttc tctttgattg gaatcttgga
     2701 tactgtctcg caattgttca ttatgcctcg attgctcaaa aaattttcag aacagcagat
     2761 cacaagaata gggatgttca gtgaaatcct cgcctatcta ttcatcacat tatctggaat
     2821 tcttctactg ccgattttgt ttttatttgg gattatctgt tatggtttcg gtgattctat
     2881 ttttactcct gtattcaatg gccaactatc caattctgtc tcagataacc agcaaggtct
     2941 tgtaatgggc ggtacccaaa gtatacaatc tctatcgcgc gtcatcggcc cgctaatcgc
     3001 aggacagctt tatgctgcag caccatttct tccgacggta ttcggatttt tgcttatgat
     3061 ttttgcctat tatcactaca ataaaaaata gtagcttcat ttgctacttc gtataaattc
     3121 tctgtatcga ccgataaaac gaaatactgt gtcaaattct tcttttgaca tattttcaaa
     3181 tacagtagca tctcgctgta cccatttttg atggagttgc tcgtgtctat tccttatttt
     3241 ttgtccgatt ggcgtcaatt gaaaatagat ttctttttta ttctcttcgc tttgataagt
     3301 gtttatgatc cctctagcta tcagtttttt tgttagctta ctgatggctc ctctagtcat
     3361 gtaactagca ttcgctaatt ttgtcacgtt aggatcaggg attttcccga tatgttcaat
     3421 cacttctagt tcatttagag taaatcctgc aaattctttt tccatttctg gtttattacg
     3481 atgaataatc tcattagcta aatccagata ttcttctatt agcagttgtc ttttatccat
     3541 ttctacacct tctttttctt tcattatatt gtttttttgt ttcctattca acaaagataa
     3601 aaatattttg taggaaaacc caatctgaaa ccaagaaaaa aaggggttga caaagcttgt
     3661 cataacccct ttttctgatt aaaagatagt aaagagacag tcatcggtaa ttgtgatgat
     3721 tttttgtcat cacttaagga tgagcggcct tttcaaaaac tgtctttaaa gatcatcatc
     3781 agtttctagc acatatggct gaccttcata tgtgtactct gtattcaatg tgccgtcatt
     3841 ttcatctgag tagatgcgtc tactgaaagg aaaacgatga gaaacattat ctttggcgtc
     3901 atttgctggc atcgtgtaat attcctcttg cgtttcattc aactgagaga gtacttgatc
     3961 tgccaactca tcaatattga tcgttaattt cttcgaagca cttttataat cttctaaaaa
     4021 tgcatcttgt tggacaaaat attctttatt catcttcttt ctcacctttc ttttcaaaat
     4081 caaataaagc tgcttgttct tttatgtaac agctttatct ttgctgctta ttgtgacaaa
     4141 aaattcgaag aaagacaact aattgtactt ttcacaaaaa aagacagagg gtcgtgacaa
     4201 aattgtgtca caaccctttt tctttattgt gcagtttcga tttcgcctag cgctgcttgt
     4261 gcaagtaggt tcaagtaatt ccatgggcgg tcaaaatgtg gttggaagaa gaaatctgaa
     4321 agtgcgagat cttctacagt cattttattt tgaacagcta aagacatggt atttgctgat
     4381 tgtgtaatgt cgtatttgga catgaactga gcacctacga tacgattcgt tcctttttca
     4441 tagactagct ccatcattac tttttcagta gttggcatga actctggacg ataattatct
     4501 tcaaatacag tcgcttggac ttctagatcg ttcaaagttg cgctttcttt ggtcacacct
     4561 gtcgaaccga tcgtccagcc aaataggtaa agtcctgaag ttccttgagt accacgatac
     4621 gccattttat gatctgtcaa gttatttccc acaagcaaac cttgacgaac ggcatttgtt
     4681 gccaaaggaa tatagttttg cgtgccactt ggattgtagt tgactactgc agagtctcca
     4741 gctgcaaaaa tgtctggatt acttgtctgc atgtattcat tcactttgat tgccccgttt
     4801 ggcagtgtat ctacttttcc ttcgatcagt tttgtatttg gacggaagcc cacacataaa
     4861 atgaccatat ctgtatcaaa tgtatctgtt ggtgtagcta cttgtttcac ttttccttct
     4921 tcatctgtga taaattcagt aacattttcg cctagcgcaa gagtaacacc gcggtctgtc
     4981 aattcttttt ctaagatatc tgtgaatggt ttatctagat atttattcaa gatgcgatct
     5041 aatccatcaa tcaatgtcac ttgttttcca gattcgacaa aagcttctac taattcaata
     5101 ccgatatatc caccaccaac aattactaca cgttttgctt ctttcgcttg tgcaataatt
     5161 tcatttgctt gattgtagtt tttgcatagg agtacatttt tcgcatcgat tccactaatc
     5221 ggtgggataa taggccatga accagttgtc atcactaatt tatcataaga aaccgtttct
     5281 gtttctcctg ttttcagatc ttttgccgtt actgttttat tttctgtatc gacgtctgtt
     5341 acatcgtgtt ccattttaac tgttgctcct aatgaagata attcttcagg atttgagtag
     5401 aacaagcctg ctgggtcctt tactactccg ccgacataaa gtgcgatacc gcaagataag
     5461 aaagaaatat tgtcatttct ttcatatact gtcacttctg cttctggatg attttttaaa
     5521 atacttttta cagctgcagt acctgcatga gtacagccaa ttactactac tttcatttat
     5581 ggtccctccg attaacattt tgtccttcga caaaactact ataacagaaa taaaacggat
     5641 acaacagttt aatgcttgtg aattcacaaa ggtttgtttg tagtttcatt ccttttcaag
     5701 cataagaacc caatatctac aagattctta ttttaataat attcactttt atatctaaga
     5761 ttgtgaataa aagacaaaaa aataaaaaag ctagcgtttt ttttacacag ctagcttttt
     5821 ttaggtataa cacttgtaga aactgttttt acatttgcgc cttttttgct gactctttac
     5881 aatccggaca gagtccatac aattccaacc gatgttcatt aatctcaaaa tcagtcagtc
     5941 tgcttgcagc catttctata tcttcaagcc ctgggtaatg aaaatcaaca atcttaccgc
     6001 agttttcaca aattacatga taatgacgct ttgaactgaa atcaaatcgg ctagaagcat
     6061 cgccgtactt catttcttga acaaatccaa tcgaagtaaa taagcgaagg ttattgtaaa
     6121 cagtcgcaac actcatattt ggaaaccgat gttcaagtgc tttataaatc tcatcagccg
     6181 ttggatggga atgatgttca atcaaatatt ctaaaaccgc gtaccgttga ggtgtgattc
     6241 gaatgttctc tttttttaac ttttcgataa cctcttcgac taacttattt tccatgtaaa
     6301 caccccacgt tgttattctc gtcttatcat actattttta cattttaaaa tccacttaac
     6361 atgaaaagaa aattcaattt tattgtattt taatgaaaaa agacgtaaaa cagtcgcgtt
     6421 cactattcta cgtctctatt caaataattt ttctcatcat aaatttttgt gtgttctttt
     6481 catctttaaa agttttttac ataaacctat ctggagaaaa accaagtgcc ttatatctct
     6541 tggtaaaggg ctgtagataa ataacgttca ccattgtcgg gaaccacagc taataccttc
     6601 ttgccttttc ctaattcttt tgcgactttt agcgcggcag caattgcagc gccagatgag
     6661 atgcctacta aaatcccttc ttttcgccca acttctctag ctgtttccat cgcttcgtct
     6721 ccactaatag aaaggacttt atcatacaca gaagtatcca gtgttttagg aacaaaacct
     6781 gtaccgattc cttggatttt gtgaggtccc gcttctttcc cttctaaaat agcagattct
     6841 gctggttcta ccccgattaa ttcgattttc ggatacacac gttttaattc tcggccagcg
     6901 ccagtgatcg ttcctcctgt accgatacct gcaacaaacg cgtccaagcc atttactcca
     6961 aatgcttgat gtatctcagg accagtcgtc ttctcatgca caagaggatt tgcttcattt
     7021 tcaaattgta atggtaaaaa gtagccgttt tcttttgcca aacgttctgc ttctctgatt
     7081 gatccagaaa taccatccgc accaggagtc aaaatcaact ctgcgccgta ccctttcatc
     7141 aataaacgtc tttcgatact catcgtctca ggcatcacga tgattacttt atatcctttt
     7201 gcaactccta ccatcgacaa tccgattcct gtatttccag aagtaggttc aatgatagta
     7261 tcacctggtt tcagtagacc atcgtgttct gctttttcta tcatacttaa agcaatacga
     7321 tcttttacac ttcctcctgg attaaaaaac tcaagcttta caaaaacatc tgctgaatct
     7381 tctggtacga ttttatttaa tttgacgatt ggcgttttgc caatcaattc ggtgactgag
     7441 ttatagatag ctgtcatctt caattcctcc ttgtctttgc tcttcttact tatcataata
     7501 caatctgttc atttatggcg agtgattcgt ctttgactag caaaaaaaag acaaagatat
     7561 accatatatg gtaatttctt tgccttttta tctaaatcaa acgtttagtt cttgaccaac
     7621 taataaagaa taactggaca tagacatgcc atttttcgcc attagatcat caacagacat
     7681 gccaaatttt tgtgcaatat cccatagcgt atcacctgac acgactgtat atgtctgacc
     7741 attatttgta tttacatctg ttgttgaaga tgatgacgtt gaagtcgtcg tagtagtcgt
     7801 tgttgttgta cttgtggttg ttgtagccga acctgttgat ggcgtatcaa aacgggttaa
     7861 attataagta ttaatcaatg agttcaattt ggccccataa tttggatcgg tagcataacg
     7921 acctgtcaag tacgctgttg catcataaaa acttgttgta ttgcttttcc acacgccagc
     7981 ataatgataa tcgcccgtgg aaaaactggt tgaacgaaga acattcgcat ggtcttggaa
     8041 ggattcccaa taagaagaat attttcggaa tggctcattc atcgttaccc attgtccgtt
     8101 tacatattct ttggttgcca tataaacgac ctgtccgtta tagcttcctt tcacaccgaa
     8161 tagattataa tttggcgcac tagctaatcc ggaagtgcca tatgcacttt ccaacaacgc
     8221 ttgagcgatc atgactgaag catacaagtc attacttgca gcaacttctg acgcagacca
     8281 gccgatttga tcgataaacg cttgaggatc agcgactgtt tgagatcctt gttcatctgc
     8341 atgaacatgt tgcggtaccg ctgtaaccat catcggccca actaaaagac tcgttccaat
     8401 taaaggagca atcgcttttt tattgatcac catttttctt ttaggtctat ggtgccgggc
     8461 actgcgggtc ttcagctctt gcattcaaat tcctcctcaa aataaaaaaa cttaataaaa
     8521 agttctcttc ttaaaacaaa cttaattaat taaattatac ttttaa
//
LOCUS       DAJSMK010000093         8508 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.097, whole genome shotgun sequence.
ACCESSION   DAJSMK010000093 DAJSMK010000000
VERSION     DAJSMK010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8508
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.097"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            134..2743
                     /gene="clpB"
                     /locus_tag="ON488_002229"
     CDS             134..2743
                     /gene="clpB"
                     /locus_tag="ON488_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HCR3232394.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(2894..3580)
                     /locus_tag="ON488_002230"
     CDS             complement(2894..3580)
                     /locus_tag="ON488_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232395.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(3558..4052)
                     /locus_tag="ON488_002231"
     CDS             complement(3558..4052)
                     /locus_tag="ON488_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HCR3232396.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(4072..5292)
                     /locus_tag="ON488_002232"
     CDS             complement(4072..5292)
                     /locus_tag="ON488_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232397.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            5439..7274
                     /gene="lepA"
                     /locus_tag="ON488_002233"
     CDS             5439..7274
                     /gene="lepA"
                     /locus_tag="ON488_002233"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HCR3232398.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(7368..8495)
                     /locus_tag="ON488_002234"
     CDS             complement(7368..8495)
                     /locus_tag="ON488_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3232399.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         2741 a         1627 c         1707 g         2433 t
ORIGIN      
        1 tttatataag tcgagaaaaa aagtcaaaaa accatgtgta tattttgacc aaaattgacc
       61 aaagcgatat aatagttttt gtaaagatca aagaaataag tgatcttacc tttaattagg
      121 agggtatacc tgtatgaata ttgagaaaat gactacgacg cttcaagaag cgattgctga
      181 agctcaacag attgcggtca ctcgaaaaca tcaagatatc gacattgccc atgtatggaa
      241 aatcttttta caacctaatc attttggtcg aaatttctat acggatgccg gattggatgt
      301 cgaatctttt gaacatgaaa ttgatcgtct actggatgag tatccagttg tttctggtgg
      361 aaacgtccaa tatggacaaa acctcagcca gaatttcttt cgattattga atgaagcaga
      421 ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg gaagtcgtta ttttagcgtt
      481 gatgaaatta aaaaattatc cgttaactgt ttatttgaat aaaaacggat tatctgaaaa
      541 agaattgcgt aaaaacatcg aagagatgag aggaggagaa agagtgacct cacaaaacca
      601 agaagaacaa tacaaagcat tagaaaaata cggcgttgat ttagtacagc aagtcaaaag
      661 cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc cgtgatgtca tccgtattct
      721 ttcacgaaaa acaaaaaata atcctgttct gataggagaa cccggtgtag ggaaaacggc
      781 aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat gtgcctgaaa atttaaaaga
      841 taaaacgatt ttttcattag atatgggtgc attgatcgct ggagcaaaat tccgtggtga
      901 atttgaagaa agactaaaag cagtcttgaa agaagtcaaa aaaagtgatg gacgtatcct
      961 cttgttcatc gatgaaatcc acaatatcgt aggggcagga aaaacagaag gaagtatgga
     1021 tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa ttacatttga tcggtgccac
     1081 aactttagat gagtaccgtc aatatatgga aaaagacaaa gcgttggaac gtcgctttca
     1141 aaaggtatta gtcaaagaac caacagtgga agatacgatc agtattctgc gtggattaaa
     1201 agaacgtttt gagatccacc atggtgttaa catccatgac aacgcattag tagcagcagc
     1261 tactttatct gaccgttata ttactgatcg gttcttaccg gacaaagcaa tcgatttgat
     1321 cgatgaagcc agtgcaacga ttcgggtaga aatgaactct atgccaacgg aattagatca
     1381 agttactaga cgtttgatgc agttggaaat cgaagaagct gcactgaaaa aagaatcaga
     1441 tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa ttagctgaac ttcgtgaaga
     1501 agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa gaagtcaatt ctgtttcagc
     1561 aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa gatgcagaaa ataactatga
     1621 tttagaacgc gctgctgtat tgcgtcatgg tacgatacct caattagaaa aagaattgaa
     1681 ggaattagaa gctaaagcaa aagacagcga gattaagatg gttcaagagt ccgttaccga
     1741 aaatgagatt gctcaagtcg ttggcagatt aacgggtatc cccgtaacga aacttgtaga
     1801 aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt cataaacgag tgattggtca
     1861 agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt tcacgggctg gattgcaaga
     1921 cccaaatcgt cctctaggtt ctttcctttt cctaggacca actggtgtcg gaaaaaccga
     1981 attagcgaaa gcgttagctg agaacttgtt tgactcagaa gatcatatgg tacggatcga
     2041 tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta gtcggagctc ctccaggcta
     2101 tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc agacgaaatc cttatacaat
     2161 cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc ttcaatatct tgttacaagt
     2221 cctagatgac ggacgcttga ctgattcaaa agggcgagta gtagatttca aaaatacggt
     2281 tctgatcatg accagcaata tcggttcaca gttactgctg gaaggcgtga ctgctgatgg
     2341 aacgattcca gaagcagtgg ctgaacaagt caacacgcta ttacgtggaa acttcaaacc
     2401 agaattcttg aaccgaatcg acgacacgat tttatttaca ccattgagcc tagacaacgt
     2461 gaaaggaatc gttgacaaaa tggtggcgca attggcacaa cgtctggaac atcaagaaat
     2521 cctgctgaca atcagtgatg aagccaaaac gtggattgct gaaaatgctt atgaaccagc
     2581 atatggtgca agaccattga aacgatttat cactaaggaa gtagaaacac cactagctaa
     2641 agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta acgattactt tacttgatgg
     2701 acaacttcat ttcaaaacag aagagctaga agaaatcgtc taatcttcca ttgagactat
     2761 aaaagaaaaa aggggtctga cacaactagt gtcagacctc cttttttcaa ataaacagtg
     2821 ttccagaagt agtttcttcg aaaaataagc cgaaatttct tgaagctgcc cgcttctgtc
     2881 acaacctctt ttattaggta tttttcactt tttctaattt ataactttca aagtaacgct
     2941 catctttttt actttgagac catgcaaaca atcccattaa ggcagcacct atcgtatttg
     3001 tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc gacaaacagt gtgccatcag
     3061 aagcagcaaa acgttgaaga ttcatgccta agaactggtc gcataagaat tcccagaact
     3121 cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa taagaggaac aaccaaggac
     3181 tggtttttga tatctcagca tctttcatca agtaaccaat caatccatag ccaagagctg
     3241 tcaggaccat tggactcacc gcatgtaaga ttttgtccca aaaagagatg atactgatca
     3301 aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa aaaccagtaa aacaaaacga
     3361 ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac ttgtggcatg aaaatcaatg
     3421 caatccctaa taaagattcc acgataaatg tgattccttg agaagtcgaa tatttttgtg
     3481 tgataaattc ataaaaatta tagcagacaa cgaatacacc aaaagcaagt aaagctattt
     3541 gcaccttttt gatttcttta atcactgaaa gtccctccat ctaaaaatct ttttacttct
     3601 gaaagcaact caatttctga agaaaccact tttccgttca atttgatcaa acctattgta
     3661 tataagttca ggtagtgaaa ttgattttca gctgtttctt gtagtgcagc gatttttttc
     3721 gggtgggttc cgccttgctg tcgagtatca gtatataagc cgatcactgg gatgcctttc
     3781 gcataagcca caccgatttc cgatgctacc ccggcatcga tcgtcagccc atctagtaaa
     3841 gcaatcatta aatcactagc caacactttt tctgtgtcag caagagcaat cattcgactg
     3901 tctgcataag cagttttgtc attgattgct tcattttctt gaggaagata gatcgaaagc
     3961 tcagaagaga gctctctgat ttctttaact aactgttggt tatataacaa atcactttta
     4021 gcaaacattg gtgcggcaaa ataaattttc atctaaacat catccttttt atcaaaaata
     4081 atcgctaaag taagcttcca tgtttggaat gatacgctct agtgacttca gtgtttcttc
     4141 atctgtttct aaccgttcga ttcttgccaa ataagaagca cggcgataat tcatcatcaa
     4201 gcaagtcaat gtttggatat ccagtcgaac ggattttcct ataggttcat ttaagacacg
     4261 gacttgtccc tgttcatccc atgttaaagc gaagacacca ttattccaag gagcgacagg
     4321 atcttcaatg atgaaatgaa aagcatcagc tgttccaaca aacggaaacc gttgaaggaa
     4381 ttcttttaca tcaacgatcc gagccataaa atatggttcg atctgctctt tgatctgact
     4441 atcttcaatc aaaaatgcta aaggctcatt tttataaata tctccatgta cccagtagat
     4501 catggaaaaa tgtgcggaaa taaagttcca taagccattt cgagcttctt gatcaagata
     4561 gaacatttct tttacgtgaa atatttcttc agctacccag tagaacagaa cacctcttgg
     4621 ttcatggttg ctatcgtagt agacagcggc tgtgcgctca tcttcatttt cgaaacgcca
     4681 atactcttcc caatgaaaat cactgcggaa taaagcacca tggttttgtt gggcaaattt
     4741 gtcataaacg gaaaatacgt ctggatgatc aactggtaat cgctcaacca taccacttac
     4801 tgggatttgt ttaggtagct gtgtatctct gattttaaag gaaagtttat cagacatgat
     4861 ttcccatcct ttacgccgat agtaggggat actgtaagga tacaaataag agatccattg
     4921 cttattcttg cgcatattat ccaatgcaac gataattaga tcttgcatca atccatggtt
     4981 agcatattct ggataagttc caactccagt cacaccaccc attttataac gtgcaccgtg
     5041 aatattgact tcacaaggat agatagcgat ttgagagatc agtttatttt cgtggaacca
     5101 tccgaacact ttcgatactt ccaaaatcgg ttttttggaa cggataaaag ctcgtttatt
     5161 ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg aacacatagg aaagcaattc
     5221 attgaattga tcgatatgtt cttgagtgac cggttttaat tcaagatttt ctctaaaatc
     5281 tttttgatcc attttttcat ctccatttat tagcttgata acagtatagc aaaattctac
     5341 aaaaaaaact tctatagctg actaattaaa aactctttaa attactgctt ttcgttggta
     5401 taatggaaag tgctgattat atgaaaagag gagacgctat ggatataaag aaaatgaaag
     5461 aacgccaaga gcagattcgt aatttttcga tcatcgctca tatcgaccat gggaaatcta
     5521 cattggccga tcgtatttta gaaatgacgc acactgtgac gtctcgcgaa atgcaagatc
     5581 agctgttaga ctcgatggat ttggaacgtg aacgtggaat cacgattaaa ttaaatgctg
     5641 tagaactcaa ttacacagcg aaaaatggag aaacatatat ctttcacttg attgacaccc
     5701 cagggcacgt cgacttcacc tatgaagtct ctcgaagcct tgctgcctgt gagggtgccg
     5761 ttttagtggt cgatgcagca caaggaatcg aagcacaaac attggccaat gtttatttag
     5821 cgttagacaa tgatttggag atcctgccag tcatcaataa aatcgaccta cccgcagcag
     5881 atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg aatcgatgct agtgaagctg
     5941 tattagccag tgccaaatca gggattggga ttgaagatat tctcgagcag atcgtggaat
     6001 atgttcctgc accaagtgga gacttagatg caccgctaaa agctttgatc tttgactcta
     6061 tttatgatag ttaccgcggt gttgttctaa atgtccggat cacggacggt atggtcaaac
     6121 ccggagacaa aatcaaactg atgagtaatg gcaaaacatt tgatgttaca gaggtcgggg
     6181 tcttctcgcc aaaagcagtt gctagagact ttttgatggt cggtgatgtc ggttatatca
     6241 cagcaagtat caaaactgtc caagatacac gagtagggga tacagtaacg ttagcagaca
     6301 atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa tccgatggtt tattgtggtc
     6361 tttatccaat tgatacttct cgttacaacg atttgcggga agctttagaa aaactgcaat
     6421 tgaatgatgc tgctttacaa ttcgaaccag aaacctctca agcattaggt tttgggttcc
     6481 gctgtggatt cctcggactt cttcatatgg atgtcgtcca agaacgcttg gaacgggaat
     6541 tcaatctaga attgatcacg actgcaccat ccgttattta ccatgttaat aaaacggatg
     6601 gtacgactgc tacagtagat aacccggcag attttcctga acctgtaacg attcaggatg
     6661 tagaagaacc attcgtcaaa gcacagatca tggtcccaaa tgattttgtc ggtgcagtaa
     6721 tggaactttc tcaacgaaaa cggggagaat tcattacgat ggattattta gatgattacc
     6781 gagtaaatgt cgtctataat attccgcttt ctgaaattgt ctttgacttt ttcgacaaat
     6841 tgaaatcaag cacgaaaggc tatgcctcat tggattatga aatgtctggt tatcaaaaaa
     6901 gcaagttagt gaagatggac atcttgctga atggagaaaa agtcgatgca ttaagcttta
     6961 tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat cgttgaaaaa ctgaaaaaac
     7021 taatcccacg ccaacaattt gaggtgccaa tccaagcagc tattggacaa aaaatcgttg
     7081 cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc taaatgttat ggtggagatg
     7141 tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg gaagaagcgg atgaaacaaa
     7201 tcggctccgt cgaagttccg caagaagcct tcatggccgt tctgaaaatg gacgaggacg
     7261 aaccgaagaa atagcaaggg tttgtttgaa aacagtgtaa aaaataaacc atgtttacat
     7321 ggatttgcca ccggtttgcc accggtggtt tttttcggtg gcaaaaatca agaattcttt
     7381 ctaagatttt ccatgatatc gaccgtttca tttctcatct tatctgttac atgcgagtaa
     7441 gtatccatcg taattgaaat tctgctgtgg cccaatcgtt cagagatttc tttcattttt
     7501 gcgccatttt cgagaagaag tgtagcatga gtatgtctga gagaatggaa gttaaaagag
     7561 agggagagtg cattcgatat cctcctagta ttccatttca ctacacttgg cgtaactagc
     7621 tcaccgtctt ccttcgtaca tactgcattt gaatcaatgt agagctttcc atacttcatt
     7681 cgattttcta attgttgttt cttatgtttt ttcagaattg ctagcaaggt ttgtccaata
     7741 aaaatcgttc gattggaact gcttgtcttt ggcgtaccat atacccatgc gccgtcattc
     7801 tttaccattt gtttctctac agtaattgtt ccatttgaaa aatcgacatc atcccacgtc
     7861 agaccacaaa cttcgccaac gcgcattccc gtataaaatc caatattcaa aggaatatag
     7921 aaaggatgtc cttcaggagt aatttctagc atatgatcaa agtcctcaag agaaatgatt
     7981 tttagatctt ttttagtcgt tggtcgtgct tcatattttg gtatttttac atacagcata
     8041 ggattttgct tgattaatcc ccaaggataa accgccatat tcagcgcatt cttaaggaca
     8101 gagtgagtaa tagtcattgt tttcttcgag taaccctttt taaattcagc attgatgaaa
     8161 ttttgtaaaa gagcagggga gagatccgta agttttttct ttcctaaata accgtttata
     8221 tgatttttga tggtaaatcg gtagttttca taggtattgt attttagatt tagtttaacg
     8281 tattcctcca tccaaaaatc aaggtattgt tttactcgag tatccgtacc taaaaagtat
     8341 tgtcctgttt cgtcaatatc tgataaaact tttcgtaaag cagcttcggc ctctggtcgg
     8401 gtgtctccgc caactttctc cacttttttt cttgagccat catcattgat atcttcgccg
     8461 tttgtataat taagcgagac aaataaaaaa gccatttatg ttacactc
//
LOCUS       DAJSMK010000094         8490 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.098, whole genome shotgun sequence.
ACCESSION   DAJSMK010000094 DAJSMK010000000
VERSION     DAJSMK010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.098"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..173)
                     /locus_tag="ON488_002235"
     CDS             complement(<1..173)
                     /locus_tag="ON488_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232400.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="ON488_002236"
     CDS             complement(593..1714)
                     /locus_tag="ON488_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HCR3232401.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVMDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYKPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="ON488_002237"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="ON488_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCR3232402.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="ON488_002238"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="ON488_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HCR3232403.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="ON488_002239"
     CDS             complement(4304..5215)
                     /locus_tag="ON488_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3232404.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="ON488_002240"
     CDS             complement(5232..6239)
                     /locus_tag="ON488_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HCR3232405.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="ON488_002241"
     CDS             complement(6236..8365)
                     /locus_tag="ON488_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HCR3232406.1"
                     /translation="MKKKLFRIVGIVFISIVLLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8490)
                     /locus_tag="ON488_002242"
     CDS             complement(8370..>8490)
                     /locus_tag="ON488_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR3232407.1"
                     /translation="GQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2600 a         1726 c         1485 g         2679 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtttgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccatca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca ataggacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg
//
LOCUS       DAJSMK010000095         8068 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.099, whole genome shotgun sequence.
ACCESSION   DAJSMK010000095 DAJSMK010000000
VERSION     DAJSMK010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8068
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.099"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..884
                     /locus_tag="ON488_002243"
     CDS             <1..884
                     /locus_tag="ON488_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCR3232408.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="ON488_002244"
     CDS             932..3061
                     /locus_tag="ON488_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HCR3232409.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="ON488_002245"
     CDS             3036..3725
                     /locus_tag="ON488_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232410.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4133..4819)
                     /locus_tag="ON488_002246"
     CDS             complement(4133..4819)
                     /locus_tag="ON488_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3232411.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(4955..5149)
                     /locus_tag="ON488_002247"
     CDS             complement(4955..5149)
                     /locus_tag="ON488_002247"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232412.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5199..5639)
                     /locus_tag="ON488_002248"
     CDS             complement(5199..5639)
                     /locus_tag="ON488_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HCR3232413.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5643..6488)
                     /locus_tag="ON488_002249"
     CDS             complement(5643..6488)
                     /locus_tag="ON488_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HCR3232414.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6637..8055
                     /gene="pepV"
                     /locus_tag="ON488_002250"
     CDS             6637..8055
                     /gene="pepV"
                     /locus_tag="ON488_002250"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HCR3232415.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2481 a         1515 c         1714 g         2358 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg
     4021 tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat
     4081 tttgccgttt atttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga
     4141 tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct
     4201 cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat
     4261 caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg
     4321 aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat
     4381 cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat
     4441 caaaaaaagc ttttttattt tgagcgatca ctgcctgatc ggtttgttct agtatttttt
     4501 ctagtttagc ttgatcttgc ttggtcattt tcgcactgca ttcttgcagg atcggttttt
     4561 ccaacttttc ccgcgtataa cgggctaatg aagcagatcg gatatcgatt tttgaaacat
     4621 aagtgccgga ctgtggaatg gtttttacaa gctcttgatt gcgcagttgg atcagtgctt
     4681 ctcgaatcgg tgtacgcccg atagctagtt gttcttctaa cactttatcg gagattttac
     4741 ttccgggtgc taactcggaa taaatgattt gtttacgtat agattcataa gcttgctgtt
     4801 gcaaattatt gataaccatt taaccttcct ttctatgcag atataatcta ttataacata
     4861 aatcgcttac aaatcgtgtg ggcataaaaa cacagtctgc aaaaaaagcc ctgataggca
     4921 tgcctattag agcctcgaaa agaaaaatat tgaatcaatc tggtcgtacc tcttggatcg
     4981 gtttgacacg accgccgatt cttttagcaa aagcttcgga ttcttttttg tctttgaaaa
     5041 tgagcagatt gtctaagttt ttttcccgag tgcgacagcc agttttatcg atgtaaccgt
     5101 gcattacttt aacgacatac atggggatca cctgcttttt tcttttcatt atacgaacta
     5161 ctcgacacaa tacaagaaaa atgcttagac ggtctttatt aagaatttac atcatccaaa
     5221 gaagcgtacg cttggaataa ctgttctaac tccggattga ctttgctcag cttcactaat
     5281 cgttgcgaat cagaaagtaa aaaacagtgt ttactactgc cagtagtttt taattttttg
     5341 tcttcagttc ccacaatttc gtagctaaaa tccaaccgtg ttcccgtata cttttggata
     5401 gttgggtgga tgctcacttt ttctccgtaa tggatcattt ctttatagct gcaatttact
     5461 tccagaacgg ggatgatgat cccagattct tcgatttttt tatagggaaa ccctagatgt
     5521 accaataagg ctacccgagc ctcttcaaac cagcggatat aattgctgtg atgaataatc
     5581 cccatttgat ctgtttcata ataaaaaggt tctcgcacat aacctgtaaa tttctccatg
     5641 actcatgcct cgttttccat tgatttttta caaaaataat tcatccactt cggaagtgct
     5701 tcgctgattt gtgtcggcaa aacaatatat tgttcttttg ccagctggtc tccaatgaaa
     5761 ctatgaagat aaacagctgc tgcaatcgtt tggtcatttt gaggaaactg ggctaaaaat
     5821 cctgtgatca tcccagctaa agtgtcaccc atgccgcctg ttgccatagc agcagaacct
     5881 aaaggattgg tgtagaagtg ctggtgacca taaatttttg tctcatgact tttcaaaacg
     5941 agcacagcac cgatttcctg ttgcttcttt ttgttttctt tatcccgttg ttcttgtatc
     6001 ggtagagaac tcaaccgttg ccactccatt tgatgaggtg taagtacagt ttgttcggga
     6061 tagggtagca aaagatgatt agcaacaagt aaacttaaag cagagccatc aatcaccagc
     6121 cattgttctt ttgattggtt ttctagtact tgtttgaaac gttccaaact cttagaagaa
     6181 gtacccaatc cgggaccaat caagagtaca tctgcttgct ttattacgga aagaaactgg
     6241 tcagtatccg tccaatctac aatcattgct tctggcagat gactgtgaag agcactccga
     6301 tttttttcat cagttactac agtcgtgaga cccgctccac tgtgtacggc agctaaagca
     6361 ctcataatga ttgctccgcc atattgttca ttgccgccaa tcaaaacgat acgtccaaat
     6421 gttcctttat gtgaaatctt tggacgaggt gtgatgactc ttttcactag ttgttcgttt
     6481 atcagcatcg aaaaacctcc ttttactcat tatagcgtat atttttttta gagaaaaaca
     6541 gataagaaaa ggaattgtca gattttttga actatttttt tctgtaattt gtggtatcat
     6601 gaacacgaag acttaaataa gtggaggatt aactttatga caattgattg gcaaaaagaa
     6661 gtagaagcac gtaaagaaga cttgcttgaa gacttgaaaa atcttttacg tgtcaacagc
     6721 gagcgcgatg attcaaaagt aacaccagat gcaccatttg gacctggacc tcgcgacgca
     6781 ttgaaacata tgttagctta tggcgaacgt gatggattta aagtaaaaaa tgtcgataac
     6841 tatgcagggc atattgatct tggcgaagga gacgaaacgc tagggatatt tggacacatg
     6901 gatgtcgttc ctgcaggaga tggctgggac acagatcctt atgaaccagt aatcaaggat
     6961 ggaaagatct ttgcacgcgg atcaagcgat gacaaaggtc caagtatggc agcttactat
     7021 gcgatgaaga tcattaaaga acttgacttg aaactatcaa aaaaagttcg cttcgtagtc
     7081 ggcagcgatg aagaaagcgg ctggggcgat atggcttatt atttcgaaca tgaagaagaa
     7141 ccagattttg gtttctcacc agatgctgaa ttcccaatca tcaatggtga aaaaggaaat
     7201 gtttctttag ctttacgctt caaaggcgac aatgcaggag attatgtctt gaaatctttt
     7261 gtttccggac ttcgcgaaaa tatggtgcca ggaacagcaa ctgcagcact tcaagtacca
     7321 agtgcagatg cagctatcgc gatggaagaa gcattttacc aattcatcga agcaaatcca
     7381 gtaagcggaa cgattgaagc ggacaatacg tatgtaaaaa tcgaattagt tggtaaaggc
     7441 gcacatggtg caagcccaca atctggtatc aatgcaggtt ctttcttggc attgttctta
     7501 gataactatg aattcctagg atctgctaaa caatttatcc atgtagcagc tgcttatgtc
     7561 catgaagatt tttatggaga aaaactagga gtcgcttatg aagatgaaaa aatgggcaaa
     7621 ttgacaatga atgctggact atttgctttt gaagaaaatg gtacagagga agcgaacttc
     7681 atcaatatga atttccgttt tccaaaaggt gtaacagtag acggattgca aagtgacatc
     7741 gaacaaacag tggggcaaga aggcgcaaca gttactcgag gtgctcgcgt aatggaacca
     7801 cattacgtac caatggatga tccattggtg gctacattat tgcaagtcta tgaagaccac
     7861 actggagaaa aaggctacga acaaatcatc ggtggcggaa cttacggacg tttgttgaaa
     7921 cgtggcgttg cttatggagc gatgttccca ggatatactg atacaatgca tcaagcaaac
     7981 gaatttatga gtcttgatga cttgttcaga gcaacagcaa tctatgcaga tgccatctat
     8041 cgtttggcga aataaaaata ctaaaaaa
//
LOCUS       DAJSMK010000096         8067 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.100, whole genome shotgun sequence.
ACCESSION   DAJSMK010000096 DAJSMK010000000
VERSION     DAJSMK010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.100"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            123..1862
                     /gene="yfcC"
                     /locus_tag="ON488_002251"
     CDS             123..1862
                     /gene="yfcC"
                     /locus_tag="ON488_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCR3232416.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2019..3203
                     /gene="iadA"
                     /locus_tag="ON488_002252"
     CDS             2019..3203
                     /gene="iadA"
                     /locus_tag="ON488_002252"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HCR3232417.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3314..3517
                     /locus_tag="ON488_002253"
     CDS             3314..3517
                     /locus_tag="ON488_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HCR3232418.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3618..4280)
                     /locus_tag="ON488_002254"
     CDS             complement(3618..4280)
                     /locus_tag="ON488_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232419.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4293..5795)
                     /locus_tag="ON488_002255"
     CDS             complement(4293..5795)
                     /locus_tag="ON488_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232420.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6343..8022
                     /locus_tag="ON488_002256"
     CDS             6343..8022
                     /locus_tag="ON488_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HCR3232421.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
BASE COUNT         2497 a         1434 c         1743 g         2393 t
ORIGIN      
        1 atagaaaaaa gtgattttct aataaattat tcatgtggaa atgtcatttt tactgtataa
       61 ttcatttgat tatccatttt ttattcatca aaattactga aaaaagaaag gaagaaataa
      121 atttgaagaa aacaaattct tcaggaaaac cgaaacgcga cttcactaaa ttatcgacac
      181 cccatacgta tgtcattatt tttggtgtag tcatctttgc atggatactg acttttgtcg
      241 ttccagcagg aaagttcagc acgcaagata ttgaatacaa agatgcaaat ggcgaaacaa
      301 gtactcgtac tgttttacgt caagattcct tccgttatgc ttacgagctg gataagtcgt
      361 atgtgtttga tcaattagaa gaactgcaag atcatccagc agaacgtgaa aaactggatg
      421 ttccggaaaa aggattggaa aaagtcattg ctgacggaga aaaaaatctt acgcaggaaa
      481 aactagatga aatctccttg acagatgatg tgctttacga tcagtacggc gaaaatatct
      541 atgatacttc taaaaaattg cataaaacag ccaaaatatg gggaacagat gattttggcg
      601 gctttggttt cttaaatttt gtttttgaag gactagtatc tggagataag tatggatctg
      661 ctgtagggat cgctgcattg atccttgttg ttggaggtgc ttttggtatt attatgcgta
      721 ccggagcgat cgacgcaggt atctatgcgt ttatcagtaa aactaaggga ctggagcgtt
      781 tagctttacc gctattattc tttgcttttt cattcggtgg cgctacattc gggatggcag
      841 aagaggtaat tccattctca atggtgatgg ttccatttgt cattgcgtta ggatatgact
      901 cgatcgtagc agtaaccgtg acttatgtcg catctcaagt cggaaatgcg acctcttgga
      961 tgagcccgtt tagcgtagcg gtggctcaag ggattgctgg aatccccgtg ttgtctggtg
     1021 cgacattccg attgattatg tgggtagttg ttactgcatt agccgctggt tatatgatga
     1081 tatatgcaga aaaaatccgt aaaaaaccag aaagttcgtt gacttacaaa tcagatgatt
     1141 atttccgttc tcatatcaaa aagacatctg atgaaaataa aaaattcatg cttgggcata
     1201 aattgatctt attagagatg ttagttgtcc ttgtctggat cgtttggggc gtgactcaaa
     1261 aaggctatta cattccagaa atcgcttctc aattctttgt gatgggatta gttgctggaa
     1321 tcattgctgt tcttttcaaa ttagatggaa tgaaagtcaa tgacatcgct tcttctttcc
     1381 aatctggtgc agctgattta gctggtacag caatcgtagt aggtatggcc aaagggattc
     1441 ttcttgtctt gggaggatct gatgcatctg ttccttcagc tttgaatacg attttgcatg
     1501 ggatcgggac ggcgttgacc ggtgttccag ctgtcattgg tgcttgggcg atgtacatct
     1561 tccaaagttt gttcaacttg gttgttacat caaattcagg acaagcagct ttgactatgc
     1621 caatcatggc tccactggca gatttagtag gtgtatccag acaagtagca gttcttgctt
     1681 atcagcttgg ttcaggtttt atggacgctt ttacacccgt atcagccagc ttgattggtg
     1741 tgctaggtgt tgcacggatc gaatgggcaa aatgggcaag attccaaatc aagatgcaag
     1801 gattcctgtt tgttttagga actattttca tcatgattgc cattgcaata ggtctgcagt
     1861 agtactggag acctgtaaat aaaaaagtaa tccaaacagt agataaggac tccaagaacc
     1921 gtcattttac ggtaaaatca aaggagtaaa gatcctatcg tttggattat tttttaagat
     1981 cctatcatca gttatactta aagaaagagg aaaaatgtat gaaaatcatt cgacaaattg
     2041 aagtgtttgc accagattac ttaggaaaaa tggatgtact gattgccggt gggaagattt
     2101 tggctgtaga agaacagcta gaaggcggct acgaaggagt ggaagtagaa gaactttcag
     2161 gtgagggaaa agtactaacc ccgggtttca ttgactgtca tttccatatt ttaggtggag
     2221 gaggagaagg cggttatcaa aatcgaacgc cagaagtcac attgagccaa ttgactacag
     2281 ctggtgtaac gacagttgtc ggttgtttgg gaacagacgg agaaggtaga gatatgactg
     2341 cgttgatcag caaagcgaaa ggtctggaag cagaaggaat ctccacttat gtatacgaag
     2401 gttcgtaccg attgccggta aaaacagtaa cagattctat catcaaagac tttttgacaa
     2461 ttgataaaat tatcggaatc ggagaaatcg cagtatccga tcaccgttct tctcagccaa
     2521 gttttgaaga gttcgctcgt gcagtagcag atgctcgtgt aggaggcatg ttatccggaa
     2581 aagctgggat catcaatgtc cacttaggcg gaggaaaaag aaagctagag ctattgacac
     2641 gaatcgtaga agaaacagaa attccgatca cacaattttt gcctactcat gcaaatcgca
     2701 caccagaatt atttgaagct tgcgtggcat ttgccaaacg tggtggcacg attgacttca
     2761 ctgctagcga agatcctgat ttttgggaga agacagatgg tgaagttcgc ttcagcaaag
     2821 cactgaaacg attgatcgag gaagatgttt ctttagataa tttcacgatg acctcagatg
     2881 gacaaggaag cttgccttat tttgatgaaa acaatcattt cctagggtta ggagtaggaa
     2941 gtgccaaggc attgctagta gggatcaaag aagctgtgca aaaagaaagt atccctttgg
     3001 aaatcgcctt acgagctata accagtaatc cagcacgtat attgaaattg gataaaaaag
     3061 gaaaaatcga aattggtgct gatgcagatc tgtgtatctt ggataaagaa acgcttgata
     3121 ttgatacagt tatcgctaaa ggagaaataa tggtccaaga aaaagaagtc aaagtatggg
     3181 ggactttcga aaaaagtttt taatcaacag ctctaactat cttttttaga aaacgagcgt
     3241 tctgtttgtc tgtatctgtt gttgatgtta ccctgaaggt agatcaataa acaaactaag
     3301 aggaggaagc acaatggcag atttaaaagg acgttctaaa gatatgaaag ataaagtagt
     3361 cggtgaagga aaagaagcat acggcaaagc aacagacgac aagagcaaag aaacagaagg
     3421 gaaagcacaa tcactaggtg ctgacatcaa agaaaaagct cgaaatttag gcgacgaagt
     3481 caaagacaag ttttctcgaa aagacgaaaa aaaataaaaa ccacttatta ctaattgaat
     3541 caagcaaata aaaaatccga accatatctg cgagacagat atggttcgga ttttttattt
     3601 gatcattatc ctgtttttta aacttcgatt ttttgaaatt ttttattttt tagttcaaag
     3661 acttcatcac agctttttgc tacttcaatc tcatgagtca cgatgataat acagcgattt
     3721 tgttcatggg cgatttcttg gaaaagtttg acgatatctt gtgaagttgt ttcatctaga
     3781 tttccagtag gctcatccgc tacgattagt tgatgttcac agcagatagc acgaacgata
     3841 gcgactcgct gctgctgacc tcccgaaagt ttggtcacct gtttttttgc taatatttca
     3901 tcaattccta cacgagccag tcgatctaaa gcaacttgtc gataattctc ttgcttggtc
     3961 ttagtgattt ccattgctgc tatgacgttg tctagagccg ataaataagg aagcaagttg
     4021 taagcttgga aaataatcga gacatcattt ttacgataac ttcttaaccc gattttgttc
     4081 agtgaacgat cttgatagta tacctttcct tcttttggtg catctagtcc agaaataagc
     4141 gaaagaaaag tcgtttttcc agaaccactt gctcctaaaa tagcgtacat ttttccagct
     4201 tcgaaattca gttctacatc tttataaagc gcatcttgcg gatcttgata ccaaaatccc
     4261 aattgttctg tccgtaacat caaattcctc ctttagttta ataggatttt tcttgggttt
     4321 aatcttaata tccctataga agctaaaaag acagaaaaca gactgattcc aaatgctact
     4381 ccggctaata gtcccaattg tgcaggtttg acattgattt ccaattcgct gacttgatca
     4441 gaaacagcaa atggattatt cgtggttcct tgttgaccat cgcgttgacc gccttgttct
     4501 tgtctgttac ctggcatttg tccaccgcca ggagcttgct ggttttgtgt cgtggtttct
     4561 gtctgttggt caagtagctg ctgtcccacg gcattcgcga cgacgtttcc gctaagcgaa
     4621 gcaactccta atgcaagaat catacaaata gccacttcgg taaacaattg gagaatgatt
     4681 ttacttctgg attctcctaa agatagcaag acgcctaact catgccgacg ctcccgaatg
     4741 gtaatcataa tgatcagagt aagtatgata ataccggcta cagccactag taaaacaaca
     4801 tttttagaaa aacttgccac gttgtttaaa ggttccaaca ttgactgata catggaatca
     4861 tttgattgta agctaaatgt atctgtgtcg atcagcttct cagcttcttt gagaaactca
     4921 tccattttat ctggatcaga tagagtgtaa atagcagaat ctatcgtgtt atcgtcagat
     4981 gtcccattta gttcatttgc aaaagtgtaa gaagtgtaaa gtgtattcga cggattcatg
     5041 aagttgaatt tcatacccat actgccgctt gtttcgctgg attcataaat tcctttgatc
     5101 gtcatttcat aagtggtatc ttcatcttca gtactcgtga ttgtgaaagt atctccgact
     5161 gccaggtcat ttgtttctgc tagagtagaa tcaatgacta cattgtttgt gcctttgtcg
     5221 ctgtcatcta ttccttcacc atccgtgatt tttgctgttc catcagaaaa attactattt
     5281 tgtgcagttg ctgacacacc actgatttga aagtctgctt gagtcatttg cggattcccg
     5341 cccattcctc cagcaggttc accgcctgca tcagtagttt ctgaactgtc ttcacttgaa
     5401 tcagaactag tgatggcagt tattccatct tttgccatag ctgaggcgga actttcaaag
     5461 gaataactct ttacattatc taattcagct attttttccg cgtccgttaa ggaaactggt
     5521 gtaagagaaa aactgcctgg atctggacgt tcttcagtgg tagaaccgct tgaagaagtt
     5581 tgttcctgtt ttttaaatga agcttctcga ttggcactta aagtcactgt tgctccaact
     5641 tctttttgtg cttgattcgc tgcttcttct gcagcgcttc gaatcgtgag gccagctagc
     5701 acaaaaataa gaatggctgt gaacacggca aacaataaca atgaacgtcc ccattttact
     5761 tttgtacttt tccatgcacg tttcataaaa ttcatatttt gcatccctcc tagtagatgc
     5821 atttgataat agacaaccta tcttaaagct agcttaaatc ttatgctgtt tgcacaccat
     5881 caacatgagg ttctgtatat ataaaaagtc actatagtta ttgcaaaaaa tgtggtaaaa
     5941 tgaaaaaagt atgtttcaaa ccgacgaaga agaaatgaaa gaggaatagc aaaagaaatc
     6001 ctagatgcta cagagggatt tttacgtgca tagttgttct aacaattgct gatactagcg
     6061 atttagttta tttgttgtat aataatgggg aacagctgaa tacttatata agtattctgg
     6121 ctatagcgtt tcgcaaaaga tccattttgt taatgaagta tatccaaaat aaaatgccca
     6181 tccaactgtc agaacgcgga tgtgctggta attttcctgc tgattctcca taagttgaga
     6241 aatagtgatt ttgcatatgc ttcattggaa tggctcatat atttagataa agaagaaaat
     6301 cgacatcttt aaacttggat gtcataagaa gaggtgaagt ttgtgagtac cattaaaatt
     6361 atcccattag gcggcgttcg tgaaaatgga aaaaacatgt atgtcgcaga agtgggcgag
     6421 gatattttta ttttagattg tgggctaaaa tatcctgaaa atgagttgtt ggggatcgac
     6481 gtcgtaatcc ctgattttac gtatttagaa gaaaacattg atcgtgtagc tggtgtcttt
     6541 ttaacacatg gacatgcaga tgcgatcggg gcacttcctt acttgttgtc aaaaatttct
     6601 gtaccagtat tcgggacaga gttgacgatc gagttagcaa aattgaatgt cagtcgtaat
     6661 gaagcagcca aaggatttaa ggatttccat gtggtagatg agcatacaga aatagacttt
     6721 ggtgaaacag tagtgagctt tttccgtacc actcatacga taccagattc agtggggatc
     6781 aatctgaaaa caaaagaagg tagtatcgtt tatacgggag attttaaatt tgaccaaacg
     6841 gctatcccaa tgtatcaaac agattatgca cgattggcgg aaatcggcaa agaaggagtc
     6901 ttagccttac taagtgaatc ggcaaatgca gaaaatcctc agcctgtagc ttctgaagcc
     6961 caaatagcag atgaagtatt tgatacgatc aaatattggg aagggcgtat catcgtcgct
     7021 tgtgtagcaa gtaatttgca acgagtgcaa caagtattgg atgcagcaga aaaagcacaa
     7081 cgaaaagttg tcttgactgg tcaagatttc gaacgaatta ttcgcacagc gatgcgttta
     7141 gaaaaacttc aattaccaag tgaagatctg cttgttacgt tgaaagacat gaaaaactat
     7201 gatccagaag aactgatcat tttagaaact ggccgaatgg gtgaacccat caagtctctg
     7261 caaaaaatgg caaacggtac acaccgtaat gtcaagattg aagaaggaga tttggtttat
     7321 atcactacta cgccaagcat cgcgatggaa accatcgtgg cgaaaacgga agatatcatt
     7381 tatcgagctg gtggaacagt gaagttgatc tctgagaata tgcgcgtttc tggccatgcc
     7441 aatcctaatg acttgcaatt aatgatcaat ttgatgaaac caacatattt tgtgccagtt
     7501 caaggagagt atcgtgaatt agctgctcat gcagatttgg ctcatgcagt agggatgcca
     7561 tacaaaaata tctatattac tggacgcgga gacgtgctgg aatataagaa caagcgtatg
     7621 agtgttgcag gaactacaag tgcagaaaat gtaatgattg atggattagg cataggtgat
     7681 atcggaaaca ttgttttacg tgatcgaaaa atcttgtcag aagacgggat tttcgtagcg
     7741 gttgtcacta tcagtcggcg agaaaagaaa atcatttcaa aacctcaaat tacttcacgg
     7801 ggattcgttt acgtaaaagc tagccgtgat ctgatgaaag aaagcagcaa tatgattgaa
     7861 acaatcgttg agaaacattt agaaagcaat gattttgagt ggagcaaatt aaagcaagac
     7921 atccgagatc aattaggccg ttacttattt gaacaaacaa aacgccgccc agtgatcttg
     7981 ccagtcatta tggaagctac tcaacgtcga aataaaaaat aaacaaaaag agtaagatga
     8041 acctctctat agagtgctcg tcttgct
//
LOCUS       DAJSMK010000097         7958 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.101, whole genome shotgun sequence.
ACCESSION   DAJSMK010000097 DAJSMK010000000
VERSION     DAJSMK010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.101"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            79..780
                     /locus_tag="ON488_002257"
     CDS             79..780
                     /locus_tag="ON488_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HCR3232422.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1389..2405)
                     /gene="tsaD"
                     /locus_tag="ON488_002258"
     CDS             complement(1389..2405)
                     /gene="tsaD"
                     /locus_tag="ON488_002258"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HCR3232423.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALAAKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2402..2866)
                     /gene="rimI"
                     /locus_tag="ON488_002259"
     CDS             complement(2402..2866)
                     /gene="rimI"
                     /locus_tag="ON488_002259"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCR3232424.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2873..3415)
                     /gene="rimI"
                     /locus_tag="ON488_002260"
     CDS             complement(2873..3415)
                     /gene="rimI"
                     /locus_tag="ON488_002260"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HCR3232425.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3399..4121)
                     /gene="tsaB"
                     /locus_tag="ON488_002261"
     CDS             complement(3399..4121)
                     /gene="tsaB"
                     /locus_tag="ON488_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HCR3232426.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(4312..5292)
                     /locus_tag="ON488_002262"
     CDS             complement(4312..5292)
                     /locus_tag="ON488_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3232427.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5316..6800)
                     /gene="galT"
                     /locus_tag="ON488_002263"
     CDS             complement(5316..6800)
                     /gene="galT"
                     /locus_tag="ON488_002263"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HCR3232428.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6812..7801)
                     /gene="galE"
                     /locus_tag="ON488_002264"
     CDS             complement(6812..7801)
                     /gene="galE"
                     /locus_tag="ON488_002264"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HCR3232429.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
BASE COUNT         2242 a         1703 c         1406 g         2607 t
ORIGIN      
        1 gttggtatgt taaaacttta caaattcttt aaaaaaagtg acaataaata tagtgaacaa
       61 taaggagagg actttttaat gcgtgttaat aaaatcgatt ttcacttttc aaaactcaga
      121 tatcaacctg attttgaaca tttctcggat gaagagttcc aacagatcaa ggaacatact
      181 gttcttcgtt cttataaaaa aggacagatc cttttcgacg atggtgatcc cagacaacgg
      241 ttgtatatct tgaccaaagg actcgttcgt ttagaacgtt atgatgaaag tgcaacttat
      301 tactactatg actatgtgaa tacaaataac ctttttccta tgtcaggaat gtttggagaa
      361 gagacctaca cttatacagc tcaagcgatg actgatattg aaacattcta ccttcctgtt
      421 tcctactatg aaaaattagc acgaaaaaat cccgaacagt tgatctatat gatacaaaaa
      481 atttctaaag tagttgaaat acatgaattg cgtatccaaa tcggattgac ctctagcgcc
      541 tttgaccggg taaaacaaaa tttattcatt ttgaaagaag aattgggcgt accaacaaaa
      601 gatggtcata tcaccattcc ttatccgatc accttaaaag aattagcagt gaatagcggc
      661 acgacacgtg aaactgctgg acaagtaatc aaacaactac gtgattccgg gctgttagat
      721 tatgacaaaa agcgttttac tttctgtaag acagctacta ctccagctat gagagaataa
      781 cgcgaacaaa aataagcagt gaccctgata aatatcaggg tcactgctta ttttcctccc
      841 taaaacttct gaaagatccg gcagttttag atcactggac aagactcaaa gattttctat
      901 gtgtgtttca gttatgtaat attcactgtt tgcaaaaaat actgttagat taactagatg
      961 aagcgtcttg tcctcatccg atctagatta ttcgatattc ctcgacaata aacgattact
     1021 cagtgagggc aatcagagga acggataatg ataaataagc tgtaaaaaat agcaaaataa
     1081 caataatgat taaaagtatg taaaaaatag ggctttgaca aaaacgtgtc acagccctat
     1141 ttcgattaaa cggtgtgtac ctgtcaactc ttcggtcaca agtcataatg ttcataaaca
     1201 tgaggagctg ttttttgaaa ttgttccttg tgaatcagag ttaaacgaca ggcttacgaa
     1261 ctcttgatta aacggcgttc aaaagcttgc atacgcggta ataagaacag ccaggtcaaa
     1321 aacatgagaa gccgtttttc ctgggctgtt cttattactt gatgcagggc agctttttca
     1381 caacctcttt attcagataa aaccaagctt ggatcagcat tcaactgata gctagcaaaa
     1441 tttctttttt gcatttccac atgtgctgct gctccaatca ttgcagcatt atctccacaa
     1501 agtcgaagag ggggaatcac tagttctacc tcagggagtt tagctgccaa agcatcctgc
     1561 aatccttcac gcaacccttg attggccgct acacctccag ctataatcag ttgcttgact
     1621 ggataatttt gacaagctcg aagtgtttta gtaatcaata catcgatcac acttgcttga
     1681 aagctagctg ctaaatcatt tttgtctaga tcttctccac gctgttgtgc attatgcacc
     1741 aaattgataa atgcactttt taatccgcta aaactgaaat cataattatc ttcatggatc
     1801 atcgctcgcg gaaaatggta attatctttt ccctgatgag ctagctgatc gatttctttt
     1861 ccgcttgggt aagaaagacc taatactctt ccaactttgt cataagcttc tcctgctgcg
     1921 tcatctcttg tctccccaat gatttcatat gatccatctt cttgcatata gactaattct
     1981 gtatgtcctc cgctaacaag aagtgccatc aatggaaact ggaatggttt aaccagacgg
     2041 gctgcataga tatgccctgc catatggttt acaggaataa gcggcaattg gtgtgcccaa
     2101 gcaaaagcct tagctgcaga aataccaatc agcaacgagc cgacaagtcc tggtccataa
     2161 gtgacagcga ctgccgataa atcttctgcc gacacaccag cttctaccag tgcatcttcc
     2221 aagcataagg tgatttgttc tacgtgatgg cggctagcta cttcaggtac tacgccacca
     2281 aaacgtttat gactgtttat ttgagaagca acgatgttag ataagatctc tgttccattt
     2341 ctaacgaccg ctacactcgt ttcatcacaa cttgattcaa tcgccagaat caattcttca
     2401 ttcatttcat cgtctccgtt tttaactttc tgctcataat gatcgcatct tccgtcggat
     2461 tgcgataata tgatttccgt ttacctaata tacgaaactt ttctgattca taaagttttc
     2521 ttgctgcttc attagataga cgtacttcta aaaaaacatg cagcgaatct tttatttgtt
     2581 ccgtaatcag taattgtaac aaatgccgtg catgcccttt tccttgttct gaaactgcaa
     2641 cagcaatatt tgtgatctcg acttcatcta ttactttcga gtatccaata aagccacaga
     2701 tctggttatc ttcagctaaa agcagataat cagagtgagg ctgttggatg tctgccaaaa
     2761 actgcatttt cgtccaaggt gaaccatgtg gataagcatt ttcgctaatc atccatacgc
     2821 attctgccaa gtacgcttca tcaaaatctt tttttctgca aatcaactaa tctcactcat
     2881 tttctaaaag ttttatcata tccaacgcat cttcttttgt ttcagtgtaa tatctttttt
     2941 tgatcgttgt tgcttgaaac cccaatttcc gataaagtct ttgtgcatct tgattactca
     3001 tacgcacttc taatgacatc gtctcacagc gattcattat agcaaagttc tcgatttcgt
     3061 caataagcag cgaaccgatt cgtttacgct gatatgccgg tcgaacggca atattcgtga
     3121 tatggcaatc taaaccgaac gctcttgaac cgataaaacc aatcattctt ccattatcaa
     3181 agatacctag atatagatga ggaagcggtg acttcaattc tgatataaag gcactttttg
     3241 tccatggcaa ttcgccatta tagacttctc gttcgacatc cagcagctct ttgatatctt
     3301 ctgtagtcaa ttctcttagt acgtaacgac gatcgatttg ttcgactgtt ttttctgtat
     3361 aaatcatttt atcttgaaaa aagcttctgg catacgctct aaattttttc aacataactt
     3421 tcgtctccag gtgtgtgcgt ctccaaccat ttttcttctg cttctactcg ttttaaatag
     3481 cgaggaagaa aagcttgttt ctctgcaact ggttcaacta aagcacctaa ttgagccaca
     3541 gttacaccac ttggaatatc ccatgctgga actgtattaa tcatcgcact aggcaatatt
     3601 tcctttattt cagagaagaa tttgtgacaa tcactcccga cgaaataaat agcttcattc
     3661 agcttttgta gttgtgtgaa caaatcagaa gcagaaatat gtacatcttc aagtacagtt
     3721 tctaatctat tttctttcca gcggtatgcc ccagcgtata cattttttct tcgagcatca
     3781 aacatgggca caataatatt atccacaccg atgcaattag ccgcgatggt tttcagacta
     3841 gatactccta ctagctcttt atctaatgta taagcaatcg tttttgctgt cgttacacct
     3901 atacgaagcc ctgtataaga accgggacca tcagaaaccg cgattcggtc aatgtctttt
     3961 ggacttattt gaagatctgc aaacaattgg tcgattgcag gcatcagtgt tacactgtgg
     4021 ttgcgtttga tatttgtttg tatttgtcca agaatttgtt cgtcttctac cacaccgatc
     4081 gccaaagttt ggtttgcagt atctattcct aatgtaatca tatatttgat cctttctgct
     4141 atgacattct cgccttccat tgtagcatac ttttttattc tgaggatgaa aataccaaag
     4201 gcaaaactag tacaataata catgattatc tgctggcggg caaattttgc cccttcctga
     4261 aacacaaaaa agctgcggta tcactccatt ttcccacagc ttttccatct tttatttcgt
     4321 tgattctcga ataatcaact ctgtttccac aataatcttt cttgaaaccg gtgctttgga
     4381 attacttaat tgaagaatcg tctccactgc tagctctccc atccattcgg tataaacttt
     4441 tacagtagaa agcgagggcg ttacatattt cgctacactg acatcattga agcccatcac
     4501 agaaatatct tctggtacca ctaaaccttt ttcttgaatc gctttcagtg cgccaatcgc
     4561 taatgcatca ttagctgcaa aaagcgcatc aggaacatgc ggattcgttt ttaaatattg
     4621 cttcactgct tgatatcctg actcgacaga aaaatctgct tcgataattg gaccttcgtc
     4681 gtagcctttt tctgccaaaa cttgttgaaa tgccataatt ctgggatctt ttagccgctg
     4741 atggtttttc ttcgtatatt ctgttccagc aagcatagcg atatgttgcg ctttatggga
     4801 gacaaagtgt tcaatgactt tttgaacact tgacttaaag tcgacaacta gagagtcgat
     4861 tccttgagaa gtgccgtcag aatctaccaa aagcaaggca ttttgggatc ctttcatttc
     4921 taataactga gcttcgtcga attttcctag tgcgatcgtt ccatctgccg gaagatcact
     4981 aatggaatcc cacgtttctt tcaataaagt aacgtttgct tcttctgcct ttttttcgat
     5041 tcctaggcga atagataaat aataaagatc ttcaagctct tccgtatcgt cgtaccactg
     5101 gatcaggcga agcgtttgct tagtatttgc tgcattttta cgatgtttcg tataatttaa
     5161 gcgttctgct gcttcaaaaa ttttttgctt tgtggctaag ccaacggaaa gatcaggatc
     5221 atagttgaga actcttgaaa cagtagcagg agaaactcct gccaactgcg caatgtcttt
     5281 aattgttgcc atttgtctct cctccttttt tacgtttata aaatcgcagt aaatcgttca
     5341 aacgctgcct gtcctttttc atctcgcttg aatactccag cgtcttccag tacacgtgca
     5401 aaaacctgac ctacagattt ttgtacgaca tcggtgaccg tatctttcgt caaatcagga
     5461 tgttcttttt ttaattgttc tgcccacgga cgatgatatt cagccatctg gttttcttct
     5521 cctaataaga aatgctctac ttctactagt tctggtttca aacgaggtgg taaaacagca
     5581 agccccatta cttcgatcaa cccaatgttc tcctttttga tatgttggac atctttatgt
     5641 ggatgaaaaa tcccatcagg atgttcttct gaaacattgt tgtctcgaag gacaaggtcc
     5701 aactcaaagt aattgtccct tcttcgtgca attggcgtaa tcgtatggtg tggtgtacca
     5761 tctgctgaaa aagctctgat agatactgtt tcatccgaat atgctttcca tttttccaat
     5821 actgagttag ctgcttcaat aagcaagttt ttctctgttg attgcaaacg gatcacagac
     5881 atcggccatt tcacgactcc tgcgatgact tgcggataat cttctagttt gataagtttt
     5941 tctatcggtg cttttgccat aggaaattca tgacgtcctg cctgataatg atcatgagaa
     6001 agaatcgatc ctccaacaat tggtaagtca gcattcgaac caacaaagta atgaggcaag
     6061 acttcagtaa tccgaagcag tctagcaaat gtttcctttg tgattttcat cgggcggtgt
     6121 tgttctgata aaatgatcga atgttcattg taataagcat aaggggaata ttggaatccc
     6181 cagctttcac cgtctagatt cattcgaata atccggtgat tggtgcgggc tggatagttc
     6241 aagcgacctc tatatccttc gttttccatg caaagcatgc aggtaggata gtctactttt
     6301 accgcctcgc gttctgctgc gatttgtttt ggatcttttt ctggcttaga taaattgatt
     6361 gtgatttcca gttcaccata ctccgactct gccggaaatt tgatgttttt tgcgatggct
     6421 cttgttttga tgtagtcatt tttcttactt aaattaaaga aatactcagt tgcttcctct
     6481 gggcttttcg aatagtgctg tgcaaagaat gcattgacga ctgaaggtgg cggtgtgaga
     6541 aaatccatta attgcgcttc aaaaatctct tgttctgctg gcaattctga aagaacacca
     6601 ttttctcttg ccttagcgac aagctgatcc aataagtcta cagattcttc cttaactggt
     6661 cttacttcaa tgctttctag agcatcttct cctaccatcc ctaaaagacg attctgtaaa
     6721 tataagcggt ccatttccat ccatccgcca gcttcgatcg caagtgtggc aaaatcacaa
     6781 atcgtttgac tgattgacat atctcattcc cctattcttc ataaccattt ggatggctga
     6841 catgccaatc ccatgctgtt ttgataatcg ctttgatatc tgtgtattca ggtttccagc
     6901 ccagaatctc tctcgctttt tcacttgaag cgactaatcg gctaggatct ccagctcttc
     6961 ttggtgctat ttctgctgga atttcttttc ctgtcacttc tctagctgct tctagcattt
     7021 ccttgactga gtatcctttg ctgctgccta aattgaagaa gttgctttca tttccttctt
     7081 tcaagtattc caaagctaaa atatgtgcag caatcaaatc ttctacttga acataatctc
     7141 tgatacatgt tccatctggt gtatcataat cgtctccata aacagccaag gcttttcttt
     7201 gaccaagagc tacttgtaaa atgattggga caagatgcgt ttctggtgta tgatcttctc
     7261 cgatagatgc atctgctttt gctccggcta cattgaagta gcgcaaagcg acatagcgca
     7321 tgccatatgc ttggtcacac cacttcatca ttttttccat catcaattta ctttcaccat
     7381 acggattttt aggattagct ggtgtatctt ctgtgattgg agactctttc ggctctccat
     7441 aagttgctgc agtagaagag aatacgattt tattcacgtt gaactcgtgc atgacttcaa
     7501 gtaagatttg cataccgtat acgttgttgt tgaaatacat caatggtttt tcgacagatt
     7561 ctcctactaa agagcttgca gcaaaatgga ttactccttc aatcggttcc ttttcaaata
     7621 cggaacgtag aaattcttta tcccggatgt ctccttcata aaaatgagca tctggatgta
     7681 ctgcttgttt gtgacctgtg agcaaattat ctaccacagc tacttgatac cccttttgaa
     7741 ctagctggtc tacagcgtgc gaaccgatat aaccggctcc gcctagtact aaaattgtca
     7801 taaaaaacac tcctttgatt agtaaaattg tgtttgttga ttctatataa tttaaaaaac
     7861 gaagtttact tttatggtga aaacaaacaa agtaaaattt cgtaaattca tatggtaaat
     7921 ttataataaa acatttagta aacattttca aggttttt
//
LOCUS       DAJSMK010000098         7806 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.102, whole genome shotgun sequence.
ACCESSION   DAJSMK010000098 DAJSMK010000000
VERSION     DAJSMK010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.102"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..625)
                     /locus_tag="ON488_002265"
     CDS             complement(<1..625)
                     /locus_tag="ON488_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HCR3232430.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKN"
     gene            complement(627..1391)
                     /locus_tag="ON488_002266"
     CDS             complement(627..1391)
                     /locus_tag="ON488_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HCR3232431.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1399..2076)
                     /locus_tag="ON488_002267"
     CDS             complement(1399..2076)
                     /locus_tag="ON488_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HCR3232432.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2113..3498)
                     /locus_tag="ON488_002268"
     CDS             complement(2113..3498)
                     /locus_tag="ON488_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HCR3232433.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3708..3792)
                     /gene="ffs"
                     /locus_tag="ON488_002269"
     ncRNA           complement(3708..3792)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="ON488_002269"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3815..4330)
                     /gene="tadA"
                     /locus_tag="ON488_002270"
     CDS             complement(3815..4330)
                     /gene="tadA"
                     /locus_tag="ON488_002270"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HCR3232434.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4437..5294
                     /locus_tag="ON488_002271"
     CDS             4437..5294
                     /locus_tag="ON488_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232435.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5375..5710)
                     /locus_tag="ON488_002272"
     CDS             complement(5375..5710)
                     /locus_tag="ON488_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232436.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5777..7147)
                     /locus_tag="ON488_002273"
     CDS             complement(5777..7147)
                     /locus_tag="ON488_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HCR3232437.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7225..7761)
                     /locus_tag="ON488_002274"
     CDS             complement(7225..7761)
                     /locus_tag="ON488_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3232438.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
BASE COUNT         2226 a         1664 c         1264 g         2652 t
ORIGIN      
        1 tattttttcc taagaaaaga aaaacagcaa aaaataattc taataataca aaaaataaga
       61 taaagctatg catgaaaaat tcttctggaa gtacattgat gattggatca gtaacgggat
      121 cgaataacca gtcatcgttg ttgaaaaacg tttcatgaaa aaggataaaa aagcgatcaa
      181 atcctatcat catgaaaaaa ccgaaaacaa ctggcagtaa catgccgatt tgaaacggac
      241 gaatcaaccg ccaaagccga tcattctttt gcaaatattt gataaacaaa atactcggga
      301 tcaaagtgat gaaaaacaca gcataatcca ctaaaaacaa aattttcact tcataaaagt
      361 gatgggctcc gctagcagaa actgggaaat ctggcaagct gaggatggtt ttgaagggat
      421 tattgagata attcattagg tgatcaaaat ttttcagtaa cgtctcttga tctaaagaag
      481 tataatccaa aatttgcaaa tgtccgatat caaatacgta tagtggtcga aagttgatcg
      541 tcacaccaac tgccagactg atcagtgtca gaaataggct gaacaatcca gcatattcca
      601 tccactgcca tctcgaattt ttcatattag aagctccatt catccagtga ttgtttcaca
      661 taggtagctg ggataggcaa cccaggtaca tcttcttctt ttgtaaaacc tgataaaacg
      721 agcaaagtat ctatattatt gcgtatccca gcttggatat ctgtttcata gttatctcca
      781 accatgatta cttcttcttt ttgcagccct aatacttcaa cggctttatc cataatgatg
      841 gcttctggtt ttccgatgta gatcggcggc gtttgggttg ctgtctctac aaaagagatg
      901 actgaccctg ctccaggaag aaggccgcgt tcagtaggta tattcttatc tgggttcgtt
      961 ccaatgaaag tagcaccttt ttgaatagca agtgttgctt taactacttt ttcataggtc
     1021 agataattat ctaagcctac cactacatag tcaggagcct cttcttccca tgtaaatccg
     1081 gcagctaaaa tcaagtcaat caatcctgct tctccgataa catagacttt tttccctttt
     1141 ccatctgctt tcataaaatc gattgttgcc aaagtagctg tgtagactgt ctctggagct
     1201 acatgaatgt caaactcatc tgctagacga ttagctactg tttctggtga cttagtcgtg
     1261 ttattggtaa caaacaagaa aggtaatttt cttttttgca attcttccac aaatcgttta
     1321 ccggccggta tgggttgtgt cccacgataa atcgttccgt ctaaatcaat taaatatcct
     1381 ttatagtcca ttcatccact actcttccct ttttctgatc gtaaatgctg tttttgtttt
     1441 ttctacttgt ttaggttgtt cttgtttttt tactttttca gaggtttttg ctgactctgt
     1501 ttttcgattt ttaataaccg gttttttgcg attagatgcg actggtcctt ttttctcatc
     1561 gatatacgca cgattatggt tttttttctt ttttcggcgc tgagttgtct tttctttttt
     1621 accgccgatt ctctcgatga caaaatacgc acaaccaaaa ttgcaatatt cgtaaagata
     1681 gtcttccaag gaatcgattc gctgatctgg atgcgcccgt cgattatccg cttggaaaaa
     1741 tccttttagg cgtagttgtt cataacccca atctcctacg atataatcat atcgggctag
     1801 tacatcactg taacgttctc caagcttttc tgcattaaat ccttcacgat aatcggacac
     1861 aagccgataa tgtctttcac ctatcaaaaa attactgtca tctaacagtg tcactagctc
     1921 gcctttgact ttttctgctt taggctcctc aacgatttct tccaaagcag ctgtcagttc
     1981 ttcggtgact gttgtttcct gttcagctga tgattttttc ttagcaattt ctgttttatg
     2041 ctcaacgttc tgctgttcat tttgttttgc agacatgcgt tcaccaccta tcttttttat
     2101 tataccttgt ttttatttga ttgggtagtg agctttcaag taatctccta ccacacttcg
     2161 gataaattca gggaacaaaa attcattttt tccagcaatc tcaatcgttg gaaaaaatgg
     2221 aacaaacatc aaatgatcta cggtagtaaa agtataattt ttattcagat cgattggctt
     2281 gttcttccaa aagacttgat ggttaataga atcatatgtg attccattat agaccatctg
     2341 cccaaaaatc ttaccgcgaa atcccattcc cttcatagga tagttacgta aaaagttacg
     2401 atttttttct atttctaaaa ctaagcggat cagatcattt ccacccaatg tgacatttaa
     2461 caagtgcatc ggatgcggca acgcagtgtg aagctgatcc tgattgaccc gcccttttgg
     2521 aatttcagtt aaaaacagac cactgtttaa tattgctgct tccgtctttc ctcgttcttt
     2581 caccgcctca aaggctactt ggataaacga atgctcattg aagatatcta gactcagaga
     2641 aaatggcaaa tctgctactt ctttttcttt taataattca tgcccacgtt ctagataact
     2701 atttatttct tgttcatctt ctgtaaaagc tgtcattgtt tcggtaggga tggctttggc
     2761 tgaatgctta aggatttttt tctcttcatc gatggttaaa tggacttcac cgacatactg
     2821 cccgtacttt ccagcggctg ctatttggac atcattgatt acgtgacctt ctctgaataa
     2881 atgatgggtg tgcgatccta aaataacatc aattgctggt atttcttttg caatttggaa
     2941 atcatcctga atcccgagat gactcatcaa aactaaaaca tccacttgtg aacgtaaatc
     3001 ttcgactaat tctggcaaaa tatcataagg attccgtatg tcccagccat tcggattata
     3061 agtaagcgga aatggagcag taaatgcaat tagtccgatt ttcgtctggt gtttcgttgt
     3121 aatgatttta tatggtttcg tccatgccgg tggctggagc gtatttttat cgaataagtt
     3181 atccaggatg atatcaaact cagcatgatc gtataaatga ttcaactctt ctttggaatt
     3241 tcctacgcct tcattgtttc ctatcgtcgc tgcatcataa ccaacttcat tcatcagcaa
     3301 gatattttcc tgtccattcg ttgcttctga caatggatgc caacgatcca caaaatcacc
     3361 tagatctact gcaatcgttg tcgttttttc tttcttttcg ttttctcgtt tacgttgatc
     3421 caaaaacctt ctgatccttg gccaattttc taaatgagaa tgcagatcat tcgtatgtaa
     3481 aatcactatt ttttccatgt accctctcgc ctctctttat ctttatcata ccataggcag
     3541 ctttttcttc cattgaaaca agctctattt cagagttttt cctgccttga agcaaattgt
     3601 ataagtacaa tattcgataa atcagtctgg ctaaaaaatc aggaacattc atttttacag
     3661 tactataaaa ataaaaaaaa cagacccgaa agtctgttgt cgtttcatta taatcagaca
     3721 catggcggaa cctgcttagt gctgcttcct tccagacctg acacgcttca caagcccacc
     3781 attgtcctag cctttcggca aagaatagta taccttattt ttcattcgtt gaccagtctt
     3841 tttttaattt cttttttcgc tggcggagct ttcggaaaaa gtcagtcaaa atcatcccac
     3901 attcgtcttc taaaatgcca ccttctacat atgcttggtg gttaaaccgc tcgtcctcca
     3961 aaagattcat caaggtaccg gctgttccgc cttttggatc atacgcgccg aaataaactt
     4021 ctgctacacg agacaaaatc atcgcgccgc tgcacatagg acaaggctct aaggtaacaa
     4081 aaagtgcagc atcttccaag cgccagcttc ccactttttc acaggcttcc ttgattgcaa
     4141 gcatttctgc atgtgtagta gcatcttgcg tggtttctct aaggttatat cctcttccaa
     4201 tcacttttcc atccaataca accactgctc caatcggaac ttcatgaagc atttctgctt
     4261 tctttgcttc tgccaatgca aggcgcatcc atttttcttt ttctactgca tcaagatttg
     4321 tatttaccaa ttacccttcc ctgcctttgt tttttcttgt tttactttag catatgataa
     4381 aaaggctgta actaactttt ttttctatgg taaaataaat acaagaggtg aacaagatga
     4441 aaatggataa attacttgct ctttacccac aagcacagaa aaaaaactct ccagcatcag
     4501 aagcggatat cctttctttt gcaattgatg atgcttttat ctggatcaaa caagattcat
     4561 tatctcaaca agaaaccagc cttttgaaag cgttattccc tgtaatcaac gatcaaaaaa
     4621 aacacccatg gtatcactat ctttttaaag atgcttcttg tgttcaagaa aaaagctttc
     4681 gtttgatcca gcttcacgtc gaatcaaaag gagaattctt aaaaaaagaa tggcaagata
     4741 ctattttgga attatttcgc tattctgctg atttcttttt ttatacagac acagatgcgc
     4801 tcttagtcga acaaataaac cgtgattatc ttgatgctac tgaaatcaac ggtatttttc
     4861 tatctttaga tgctgatttt gatacgacaa cgtctgtatt cgttggttct ttccattcac
     4921 ctggcaccga cctcgtccct ttgtttgctg aagaaagaaa aattttttta acagagcaaa
     4981 acaatcttta tactcacagc cgtacttttt ctatgcaaga tgtggcttta cattactata
     5041 caaaagatac tgtaaaagat agtaagttga tcaaaagtta catagaactg atcaaacaaa
     5101 atgaaatgga agtgatcatt caagaattat ggaatgaatt aggcaatgtc agctctgctg
     5161 caaaaacact gtttcttcat cgtaatactc taaaatatcg aatcgaaaaa tttcaagaac
     5221 agtctggttt caatctaaaa aaagccaacg atttactgtt ttgctatctt ttattgcttc
     5281 atgaacataa ttaaagatag attaaagggg ttgtgacaat aattttgtca caacccctta
     5341 tttcgaatga atagtgttca aaagctagtt tctcttacat cattttttca acaaaatgca
     5401 ttagccggtc ttttacatct tcggttgaat ctttgattga atcaccataa acagagattt
     5461 tcttttttcc tgatttgatt tttgctaaca ttcccatcaa agaatccaag tcactatctg
     5521 aaagaccatc tacgatttct agtaattttt catttccatc aaatttgtca tagacgaatt
     5581 tttttacttt cgtccgagta gtcatatgat ggatcttttc cattactttt cccgatacaa
     5641 cgactgctgt cgctacactg gcagcggctg ctacgcttaa tccgattgtt acttttgttg
     5701 atgttttcat aagtatcagc tcctttttat ctatctccat catagcatag acaaaaaaat
     5761 aaacgaacta atccactcag tgaaatctca atcctttagg gaaaaagttc tttactgttc
     5821 cttttacttg tttcccaaat ccgacaggta tcttatctaa tactagcaaa acccatcctt
     5881 gattcccatc acgttgaaat gtttctcctg ctgtgtaaga ttgccattcc ttttgagtga
     5941 tcggcaagca aggtatattc tctatctttt ttgtagcaag cgctaatgca tagctaggtt
     6001 caaatcgatt ctttttgaaa tctcctaaat gcaaacctgt acgtacgact tttaaaccat
     6061 cgagagaagg ggctaactca ggaacttccc aaagatggtc gttgaacact aaaagtcttc
     6121 cagtagcttc ataatgaaaa tcatttgaaa actccgtcca gagtttttcc tgctcttttg
     6181 tcatttgcac tttacttttt tttcgtgtct tcttttcttt atgcatctga ttttgtccat
     6241 gaaaagtcag ctttgcaaca aaatgtcctt caccctgatc tttatgaggc catatacgta
     6301 ttgttttttc caaaccagct acgcttcccc attcagaacg tcctgaacta acggattgag
     6361 tcaaaggaat ctcctcaatc gttactggat aattttctac aagccagcta atgatctctt
     6421 cattttcttc tggtgcaaac gtacaagtcg aataaatcag ttgtccttta ttttttagca
     6481 tttttattgc tgaagacaaa atctcttgct gacgtttttg acagtatagc ggagattctt
     6541 ctgtccactc ttttattgca tttggatctt ttcggaacat tccttctcct gaacaaggag
     6601 catcaaccac gatccgatca aaaaagcccg aaaaatgagg gacaagttct gcgggtgcat
     6661 gatttgtcac tattgcgttc gaaactcccc atcgttctat attttctgat aaaatcttcg
     6721 cacgtttcgg aaagatctca ttcgtcacta ataacccttt ccccttcatt tgagcagcta
     6781 attgggttga tttaccaccg ggagccgcac acaaatccaa aactttttca ccgggttttg
     6841 ctgcagcagc tgttccaacg atcattgcac ttggttcttg gctatattca tacccagctt
     6901 gatggaggaa agactttcca ttgacagtgc caagaaatcc ctcattgctg tagggagcgg
     6961 gttgtaattc ttcgctatgg taagtttgga ccatgtccaa tcctgccggt tttagtggat
     7021 tccaccgaaa tccttttttc acgcttcctt gttcaagcgc agaaaaaaaa tcggatgctt
     7081 cttcgcctaa aagaagacga tattttttga taaattgctg tggtaacgtt gtcgcttcct
     7141 ccttcattcc aatgtttcgt tagacatttt acaatctttt ttacgaaaaa taaaggtggc
     7201 tgatctactt tttcatgttg ctgcctaagg tgactgttcc tttaagatat tttccaagta
     7261 ttcatccgtc acctcgtttt tatcccaaac agcgttcatc atttcaagaa aatcttgaga
     7321 agaatcatct gagcgcaaac ttcccaatgc attaagccat accaattcaa gcgacttttc
     7381 ttctttgatc ttcgtgtgac ctttgacata tgagaaaaat ggccgcttaa atagcgaatc
     7441 catgtctaaa tcagattttg caatgatttc acgaatactt tcatggatag aaaaaaaatc
     7501 tttcaataag tagacaatgc ttaaaacatc atcggaactg cattcagcta agtagttttc
     7561 aaaataaaca gtgatttctt ctaatatctt ctcttttaac ccgctgattg atttgaaatg
     7621 tgtataaatc gggtatgtag aacaaccgca gaactctgct aactctcttg cagtaattga
     7681 cttcattcca tattcttcca cgtataccat acttttgaac agcaaatatt ctttactata
     7741 atttgttact ctccccatca ttcttacctc cgtctctttt catctaccca taaataaata
     7801 acataa
//
LOCUS       DAJSMK010000099         7671 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.103, whole genome shotgun sequence.
ACCESSION   DAJSMK010000099 DAJSMK010000000
VERSION     DAJSMK010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7671
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.103"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            32..2359
                     /locus_tag="ON488_002275"
     CDS             32..2359
                     /locus_tag="ON488_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCR3232439.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            2485..2814
                     /locus_tag="ON488_002276"
     CDS             2485..2814
                     /locus_tag="ON488_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCR3232440.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            2854..3858
                     /locus_tag="ON488_002277"
     CDS             2854..3858
                     /locus_tag="ON488_002277"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HCR3232441.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            3855..4301
                     /locus_tag="ON488_002278"
     CDS             3855..4301
                     /locus_tag="ON488_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HCR3232442.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            4451..5266
                     /locus_tag="ON488_002279"
     CDS             4451..5266
                     /locus_tag="ON488_002279"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HCR3232443.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            5472..6644
                     /locus_tag="ON488_002280"
     CDS             5472..6644
                     /locus_tag="ON488_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HCR3232444.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(6806..7300)
                     /locus_tag="ON488_002281"
     CDS             complement(6806..7300)
                     /locus_tag="ON488_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232445.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(7297..7491)
                     /locus_tag="ON488_002282"
     CDS             complement(7297..7491)
                     /locus_tag="ON488_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232446.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
BASE COUNT         2578 a         1445 c         1528 g         2120 t
ORIGIN      
        1 attatttgat gattttttat tgagaggagg gatgaaaatg attaagaaaa ctcaaaataa
       61 aatccaacgt atatgtcaaa aacattttgt ttctagactc aaagctgtat ctaaaagaaa
      121 atacttacat cccattatga tttcgatcat cttgattttt actttcttag ggagcttatc
      181 aagtatttat gtaaacgttt atacagaaac gtcaaatttt gctaaccaaa cgacagagga
      241 gacaaatagt ccaccctatt ctgaaataca gtccatagaa agcaccaatc agtctagcaa
      301 caacgagaca acctcaacca catcctcgac tcaactgatt gatccgacag aaaaagaaat
      361 cacagcagca aaagcagcag gggagaaagc ttattcagaa acaggtagaa gccagacatt
      421 tagtactgtt gcggccactg cgaatttcaa cggacatacc ataccagatg gatatacagt
      481 gatatatgcc aaagatggag tcattgttgc ggttaacgga tcgatgagtg cggataaaac
      541 tgcgttacaa ggcgtaacca aagcaatcgc ttttattgat aaccgtccag atatccataa
      601 tctgtttatt ggctccacag taaatggtac tactatcaca ttcccaaaaa gtatctatat
      661 gggggtggct accgctggaa atacgatcga ttcagttaca cccaatgcgg ataaaagtta
      721 ttcttttaca ccctcaacat ggggagggct tcctgccgga ggaggtatga gtactttttc
      781 aatcggtata cagttagcaa atgatattcc attcacgggg tactcgatca aaaatgggca
      841 gatcgttgat ggtaagggaa atgtttcaaa ttttccaacc tatcaagcag caacggttca
      901 ggtcaatgcg aatcggacag gaactttttc ttatacagtc aatggtggag cagcaaaaat
      961 cggaacgtac gggactacat tatctggaat ccatgtgggt gacaaagtgg ttatcactcc
     1021 aacagcagta acgggctatt cttttgcaca aacaaacggt tctttcacag ccctagaaag
     1081 taacgtcgat acggtgacct atacaggcaa acaaacacca atcactatta agtatcaaga
     1141 ctattttgga cagatgattg ctccttctaa aataatgaat cttacttacg gaagtgctgc
     1201 acaagacctg acgactaata cgcctactat caacggatat acctttacag ctgtttcagc
     1261 gatagaaaca aagaaccaat cagcaatgag tgttttagct agtttagata caaatggaaa
     1321 tgtaatcgta aaggacgcaa atggaaaaca gatttctgaa gtcatcctat attataagac
     1381 aaatgcaaca gtatcaatca atgcaaatgg cagtaagtac tatgatggtc tttctgttgt
     1441 accgatcgtt aaatatgcct ttaatgataa aacagaatca acatcccttt taaacaatga
     1501 tctcagtatt gatcaaatca catggaatcc aactgatttc aaagcgatga atgaaaaggg
     1561 agttgaagta actgcgccta ctgaaattgg aacctatacg tcttggcaat tgacaaaaag
     1621 cggactagct aaactagctg ccagaacaaa ctatttattt actatcgtgc agacatctga
     1681 tgtctatacg attaagcaaa tcagcggtgc ggtagagctc agtggcagta agacatatga
     1741 tggaaaagca ggtgtcccgt caatccatgt caagctagca gagggtgtca ctagttcgct
     1801 tactccagta caagtggcac ttagcagtat ggattacaca gcagatgcac aatcagcaaa
     1861 aaatatggtt aatgctggca gctatacaat taaactaacg aatagcggaa tagacaaagt
     1921 caaagcagca aatcccaagt tgtcatttac tgatatagcc aacacatcag gaacttatac
     1981 catctataaa gctaacgcag tgattactgt cgatgacgct gcctttaatt atgatgccca
     2041 aagtcactcg atttcggttg gaaatctcca cgttaccggt gttgtcttag gcgaatcatt
     2101 ggattatacc ctaacagtta acagccggac agatattgga tcacaaatag taacgattag
     2161 tttaggcgaa ggaagtgtaa acaataatta tacgattatc gcaacagata ccgctaagtt
     2221 gacgatcaat ccgactctct tgcttccttc gacaggtggg ataggtctac tgccctttgt
     2281 ctttttagga ctgatcttta ttttttctgg cttcttttat tttatccatc gtaagaaaaa
     2341 agcaggtgaa cagcgatgaa aaaaacaaaa aatgtacgtg tggatatatt tgctgttctc
     2401 ttttttatcc tactggtctt ttttataggt tctccgactg tgtcagctag agaatcacct
     2461 attacattta ctttgcataa tcgaatgttc gaaagcgata agatgccaag tatcagtcaa
     2521 aacgacggaa taaatatccc ggataacttt caaggagtaa aagggttgaa cggcgttact
     2581 ttcgctatat atgatgtctc ggatgaattt tacaagctgc ggtcagaagg aagtagtgtg
     2641 gaagacgcac aaagaaaact agcacaaaaa agtgatagtg aaaaaatact ggcagaaaat
     2701 gtgacaaaaa cagtagacga ggaagagggc attgcttctt ttagtgcatc ggacaaagat
     2761 gagcaaggtc gtgacgctgt ttaccgattt acggaaataa agacttcaga ttaagtaaaa
     2821 gaaaaatcag caccatttgt cgttgtgctt cctgtgacag attcatctaa tcataaattg
     2881 acgaccatcc acttgtatcc aaagagcgaa caaaaaatac ctgctgcact cacattaaca
     2941 aaaacagtag agaataagca gacagatttt gcagatgggg ataaagtccc ttatctcatc
     3001 accgtaacaa ttcctgagaa catcaacgag ataggaacct atacgatcaa agatacagct
     3061 gatcctcagt tatggctaga accagaaacg atcgattttt tgattggtgg agacaagatt
     3121 catacatttc acacacaaaa aataaaacat ggttttgtct tatcagattc tggaaaagat
     3181 cttagttcgt ttgctggaaa aaaattaacg atccgttacc aaatgacatt gaaagaaaac
     3241 agtgaaaaaa cgacatttga taacgatgta cgtttgacga ctgacaatca aacagtagaa
     3301 acacatcttg ccatccaaac aggaggcaaa caatttgtca aagtggatcg gcaaacgaaa
     3361 caaaaactag cagatgctca atttctagtc aaaaaaaatg accaatactt agcgcaagaa
     3421 aacgggataa atcattgggt agccaaagat gattcaagag caacgatttt tacttccagt
     3481 aaagatggaa cattttctgt ccatggattg tcttttggaa gttacgaact agtggagatt
     3541 aaaccgccta aaggatatat attgagtcaa tcaaccattc tctttgaagt tgaaaaaggc
     3601 agttatgatc cgcttcatcc tataccattg gaaatcatca acgaaccaaa agcaaatccg
     3661 acgaataatg gaaaaacgcc agttcagatg cagacaaatg gtccatcaaa tgaaaaaaat
     3721 ggaggaagct ttccaaaaac aagcgaagag atgcttggag gtttctcaat tttagggtta
     3781 ttgctagtcc tttcaacagg gacagcttgg ttttataaaa aacaacaaaa aggaaacaat
     3841 aggagggaaa taaaatgaaa aacatcaaaa caaaaatatg gacgttttta ggaactgcta
     3901 tcatgctgct tcctttcgtt ctcggcctag gaactgcaga ggtttctgca gccgtatcac
     3961 ctacaccaga aaatgttacg gttaatttgc ataaattgaa attcacttca gcaccagaaa
     4021 atcaaataaa caacggaacg gaattgacat ttccgaatag cgaaccgttg aacggcgttg
     4081 aattcaacgt atatgacatc actgctacgt actatccaag taaagacaca gcagttccag
     4141 cagacgctac acccttcgca agtgtaacga cttctggtga aggattagct aacctgactc
     4201 ttccaggtaa atctgatggg aaagatgctg tatacgtctt tgtagaaaca ccaaagcccg
     4261 gtgtcgaaac gtcgccaaat atcgtgttaa gcttacccta gaccctgaca aacctttaga
     4321 cacgattcac ctatatgcta aaaatgtcat caaagaaagc aatatcaaaa tccagaaagc
     4381 tgggaacttt tcaggggtag ataagttagc aggggcgcaa ttccagatca aaaattcaga
     4441 gaatcaattc gtgaccggtt ttgatgaaaa cactggtgtc gctctctatg atcctgctga
     4501 gtcagcgttg acattcacaa ctgatactga aggatccatc agtgtcaatg gattaataga
     4561 cggcaattat actttagttg aaacaaaagc accagatggt tatcaattaa ccaatccaca
     4621 aaaagaaact acttttatag taaaaaacgg aaaattgcaa caaacaaccg gtatcatcca
     4681 tggcgcagat gaagccaatc ttgggaatcc aaacggtgta gtcaatcggg aaaatacaac
     4741 tacggataac atgattactg tagaaaatgt ccaaaactac ggtgatttcc acttcatcaa
     4801 acaagatgtg aacacgcaag aaaaattagc cgatgcagaa ttttctattc taagagcaaa
     4861 agatccaact gttaaattaa tgaaaaaaat agcaaacctt gcctcaggag aatacccata
     4921 tgcttggtca gatgaagtca caggttctga ctgggaagaa gtgaaattga tttctgattc
     4981 agaagggaaa ttttcaatcg aagggctgaa acaaggggca tactgccttc aagaaacaaa
     5041 agcaccagaa ggctacgcat tacctaagaa tgaagctgcg tacactgaat ttacagtaga
     5101 tgatgatcca acaacttctg atgaaacaac gatcgataac caacctaaag gaatcttgcc
     5161 ttcaactggt ggtatgggga tcatcgtatt catcttggta ggtactgctt tagttggagg
     5221 agcagtgatc tatttcaaaa aacgccatca agaaacagaa gcttaaacta ttggaaacaa
     5281 aaatcatacg ataaataaac gatagtgatt caaatgggga gaaaggttgt gacaagtggt
     5341 cggtctcttg gtattcgctc aacaaacggc aaaataggag gaactatttt gccgtttgct
     5401 tcgctaatac tcaggtcaag gcgctgattt cacaacctct tcatatacat attagaaaat
     5461 aggtggacat gatgaataaa agcagaataa gaatactgga catcttcatg gcaatcattt
     5521 tagtcgttgg gatcgggatc ttttcttatc cttttgtaga agattcactg aatgattttc
     5581 ttgcccagca aatgatcatc cattatcaaa agcaagcatc gaataagaat tcagaggaaa
     5641 taaaaaaaca gcaggaaaaa atgacaaaga aaaaccaaca gttggcagag caaaacgtat
     5701 caccagggat aggcagtttc aaccaagcag ttgatgcaaa agcattaaaa gatttaccta
     5761 gtaatgcctt ttttatggaa catatgcttg gagtcatcga aatcccaaaa atcaatgtca
     5821 gcttacctat attcgatcag acaacggaaa tatttttgca aaaaggaacg tcattattgg
     5881 aagaaagttc ttatccgact ggcgggaaaa acacccatgc cgttctttct gggcatcgtg
     5941 gactcccaga agcaaaatta tttacagatt tgcctaagtt gaaaaaagga gaccagtttt
     6001 tcatccagat caatggaaag acattggcgt atcaagtaga aaaaatccaa gtggtcttac
     6061 ctgatgaagt agattctttg ggtatccaaa aaggcagaga tctcgtgact ttgcttacct
     6121 gtactcctta tatggtcaat acacatcgac tgcttgtgac ggggcatcgt attccttatc
     6181 aagcaaaaga ggcaaaaaaa gcgatccaag gaattgatca atggaaaaaa tggaaatttt
     6241 ttatttggtt tatcggtata ctacttggat caatcggctt agtttggcta ctcatcgctt
     6301 atttagattc tttggccatc gctaagcgaa actatccttt atctttttat gtaaagaaca
     6361 caaacggacg accaatcgaa ggaatggtct tttctgtaaa aacgctcaac ggcaaacact
     6421 atattactag agaaaaagtt ccatttgtga aagcttctga tgaatacgga ctagtgagat
     6481 tttctgattt aaaaggcagg aactatcgct tgcaacatga ggagctcctg cttaaaatcc
     6541 atgtaaaaca taaacattcg aaacagtttt caatgaaatt gaaaaaagga agatataaac
     6601 tgcgaaaaga aaaagaggtg tactatttga ttgagaaaga atgaatgaag atgtccaaaa
     6661 aagcagaggg aacagactaa atgaaaaaag agagaagctg acgaaatgga cgtgtaaact
     6721 gttatttttg gtttactatc tggaacgcca tcttctattt ttttatgttt cagaagaatt
     6781 ttattattat agtataactt ttgaattagt ttccataaca tttggagcaa ggggttaaac
     6841 cacgagcttg agcttcgctt aaagtggcag gggtatacgt accatttcca catttatgtg
     6901 tatggtattt tgaaccggtc ggtgtgacat agacagtttg ttcattattt tgctcaggag
     6961 ctgcggcttg tgcctgctga gaggcctgtt cagctgctga ttgctgtcgc gcctgttctg
     7021 cttgttgctg tgcgattgct tcttgcctcg cctgttctgc ttgttgctgt gcgattgctt
     7081 cttgttgcgc ttgttctgct tgttgtcgtg caatttcttc ttgctttttc cgttcttctt
     7141 ctgcttcttt tgctttgatt gtggaatcaa ttgcagcaag acggcttgtc aactcttgtt
     7201 tgttttcagg tagcgcttgg atagctgctg aagcagttgc atagttttct tttgtaggat
     7261 ttgcttcagc ttgtgacaaa gcagattccg cttctgtcac tttttttcta gtgcagcttt
     7321 ttccgctttt tgtttctctt cttttttctt ttcaatttgt tcttgttctt tcgatgaatc
     7381 tgccgtactt tcggagatcg tggtactgct gctggaagcc tgatctgaac ttgtgctttg
     7441 agtagtagac gtagtagcac cacacccact caacaaactt cctgcgacca aaaacaatgc
     7501 aactaatttt ttcgctaaat ttcctcctta agtaaaaaac aaccgttttc aataaatgtc
     7561 cttttcaatt gtttacttac ttgttataat aattgtgtta tgaatagtga ttgaggaaac
     7621 ttaatctaat cccgtgttga tacacgggat tttttgctat agttctgtta t
//
LOCUS       DAJSMK010000100         7585 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.104, whole genome shotgun sequence.
ACCESSION   DAJSMK010000100 DAJSMK010000000
VERSION     DAJSMK010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.104"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(152..622)
                     /locus_tag="ON488_002283"
     CDS             complement(152..622)
                     /locus_tag="ON488_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCR3232447.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWGKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            complement(619..861)
                     /locus_tag="ON488_002284"
     CDS             complement(619..861)
                     /locus_tag="ON488_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HCR3232448.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            complement(1407..1937)
                     /locus_tag="ON488_002285"
     CDS             complement(1407..1937)
                     /locus_tag="ON488_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCR3232449.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(2119..2775)
                     /locus_tag="ON488_002286"
     CDS             complement(2119..2775)
                     /locus_tag="ON488_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HCR3232450.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(2902..3375)
                     /gene="dfrF"
                     /locus_tag="ON488_002287"
     CDS             complement(2902..3375)
                     /gene="dfrF"
                     /locus_tag="ON488_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HCR3232451.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(3794..4012)
                     /locus_tag="ON488_002288"
                     /pseudo
     CDS             complement(3794..4012)
                     /locus_tag="ON488_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4043..5256)
                     /locus_tag="ON488_002289"
                     /pseudo
     CDS             complement(4043..5256)
                     /locus_tag="ON488_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
     gene            complement(5597..5839)
                     /locus_tag="ON488_002290"
     CDS             complement(5597..5839)
                     /locus_tag="ON488_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCR3232452.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(5871..6428)
                     /locus_tag="ON488_002291"
     CDS             complement(5871..6428)
                     /locus_tag="ON488_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCR3232453.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(6441..6629)
                     /locus_tag="ON488_002292"
     CDS             complement(6441..6629)
                     /locus_tag="ON488_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCR3232454.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(6642..7208)
                     /gene="amaP"
                     /locus_tag="ON488_002293"
     CDS             complement(6642..7208)
                     /gene="amaP"
                     /locus_tag="ON488_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCR3232455.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
BASE COUNT         2295 a         1554 c         1085 g         2651 t
ORIGIN      
        1 ttcaataaag tttttatcat tcattcttca attcctccaa tcaaaaaagg caactaccat
       61 aattgataat tgcctgtcat taaaaatctg tatagaaaaa gcagtcaatc ctaagactaa
      121 ctgctttgtg tgtatggata taaaattgct tctaatcttg aataggtatc caaatttcaa
      181 taactgaatt atcactattc caatgaaaac gataatcgta tttttcaaag tgtaggataa
      241 tatcttttat aggaatatac gatgtactag gaataatttc ttcataaatc ttgccataag
      301 tttcatatat tttatccata gcaccaatat gctccacaac caaatattta taagacggta
      361 tttctttata cagaaagccc tctggggtaa tggttctttg gggaatagaa cagaaataat
      421 aaagttttcc atttcttctt tccataaaag catattttac ccaatttcct gattgtgaaa
      481 gatacgcttt tttcaaacta ctgttaaact ttccccaaaa ctgtgtacta atctgaatat
      541 tctttttttg ataattagtc agttctactt cctgcccaat aactgcaaat gcgtttaatt
      601 cctttataga aaaatttatc attttacctt gtgagcagtg ataacggtat aactgtacgc
      661 atttaccgtt ataatacaat tatcaatcgt tatataccag ttttttcctt ttcttgtgat
      721 ttccgcatta gaaaggctaa ttttttcttt gcaccattca attacatttt ctacattcaa
      781 agataagttc tttttaattc taataacgcc aagttcagtt gtgtgaagtc ttcctaagtt
      841 ttccagtaat tcattttcca tattttgata cctcattttt cagcaaattt atttgtatgt
      901 tttatacccc aattataaca ttctcatatc agcactacaa taaaaataat taagcaccaa
      961 taatcttatt gaacatctcc aaccgtaaat ctttcacacc atcagtgata aacactgagc
     1021 tgacagcaat tacgacaact accataattg cctgcactta aatttctgca aaagaaaacg
     1081 acaatcaatt tcttattttt tgaaatcaac tgtctttctc atatttacta ttcaattttc
     1141 atagtgatat aggtacaatt tatatcacta ctgtaaaaat ggggttttgc cttataaata
     1201 cagcgttttc cgcttgttag tgtatagtgt ttcttgtttt ttgtgccccc cttgttagat
     1261 aacgggggct ttgaacggct cgcaagctcg ccgaaccgcc gaagcgaacc gcccccttgc
     1321 aagcatggcg gaaaaatctt aaggattttc ccgccaacgt ggtcggatcg ctccgtcggt
     1381 ttaacagctt ttctgtttct ctctagttat ctacgcatat aaatcaaatc ggttattccg
     1441 ttataagtct gtgttttaca aagccttaac tttatttccc tgtctatgtt gcccaaaaga
     1501 cgaaccccat ttcctaacag agtaggaata acagaaatgt aatatttatc aatcatattt
     1561 ttgcttacca actgctgaac aagatttgct ccgccacaaa tccaaatatc ctttcctgct
     1621 tcttgtttta gccgttccaa taataaaaca ggattttcac ttgtaaaatg aatttgttgg
     1681 gaagaattgc actctttatg tgttaataca taagttgtaa atttattata tacccattct
     1741 tgcggagaaa gttcagtaac aacctgatga gaagtattcc accccattaa gacagtatct
     1801 atatctttgg taaattctgt ataagtgtcg atgttttcat tgtcatttcc atgaccattt
     1861 agccaagcta ctccaccatt accgtccgca atatatccgt caaggctcat ggcaataaat
     1921 aaaactactt ttctcatttt ttctctttta taaatacaaa caggaattta tttctctttt
     1981 ttactcataa gggaacaact gattgctaca aataaaccca ttaaaatcca tggaaatgct
     2041 gctcttataa aatcactaac catactttat tcctccttaa attccaattt ccttagttct
     2101 acaaactgaa atttttgcct atgaatgtat cttgttcttt atacgcaaac aggcttctgt
     2161 gtgcataatc caatgtcttg aaaacggcat ttgaattagt ccacaaatat ctttattaca
     2221 ccaataatca atcagccaaa ttgctttttc attgtcgttt actacattca acgattctaa
     2281 gtatcctttt ctttctttcg gtatttttct tttcaattca tcataagata accgttcaag
     2341 cattttctca gtgctttccc atacttcgaa aatatataaa tataattctt ccagattaag
     2401 ctgttttgaa aagtctgcaa tctgctgttt catgagttca tttcctgttg taatgatagg
     2461 tgaattgata cgctcttgat aattgcctgc aaaaaatact tgttcatctt catttatcac
     2521 tgtatgcaca actatatctt caatgcggaa aatatgccaa atagaataag caatcgtctt
     2581 actatgataa ccatcagcgt ttatgaaggg gattgagtta aaatcttctc tgcataattc
     2641 ttctttgaaa gatactaagg tttgtattaa ctgacttcgt aaagtaagta aagtatcaat
     2701 acccctctta taagtatctt tcttttttat ttgtgcctgc attgttttat taagttcaga
     2761 ccattcctta ttcatattca atcctctctc aaattctgat tttatcgccc catacaaact
     2821 ggaatttgtc ttacaacaat ttatatatgc ataaaaagca atatatttat gaaaacaccc
     2881 taaatccaaa atttactcaa ttcatttttt ccttacataa aatgttctcg tatatttcac
     2941 ttcctcacca agtgtttccc ctatcaaaac ttcaaaatca ttgatatcaa attctggaaa
     3001 gaatgtatct ccatcttcaa tatttaaatc tacttctgtg atatacattt tatctactat
     3061 ttgcaaagct tccttaaata gtccatatcc accagatatg tatacatctc gtcctttagc
     3121 caataataat gcatcttcta atgatttaac tgaaactaaa ttatctcctt gatactctgt
     3181 tgtggtggaa acaacaatat tcattctatt aggcaacgga tgaccgattt cttcataaga
     3241 ctttcgcccc ataataacca cattacccgt tgttaactct ctaaattgct tttgttctcc
     3301 ctttattttc catggtatat taccattctt gcctataaca ttattctttg acctcgcaac
     3361 aatcaaacct atcatctatt tcatcctcca taatatgatg tcgtacctgt gattccatca
     3421 agtgcaccac atcttaacaa actcaaaatt atctcgaact aaccagctcg acaaattcct
     3481 tttttgtctt catctgcatt atatcatatt gttataagca ttgccatttc ttttctgctt
     3541 ttgaaaagtt acttatcagc ctatgttttg taaagggtga tattcagcat ttctcacgca
     3601 acaagccctt gacaaaccat agactaataa gttttaaggt aatcaagcag aaatgaaata
     3661 gtctgctgtt tcacggcaac aaaaaagaga taccaacaca cttatgtagt atctcttagt
     3721 ctagtagcaa tattcttttg tttgcaagca ggtaaacatg ggctgtttct taatatcttt
     3781 ttgtttggga aacacctttt tcccatcctt tcaccgttgc catctctgct gcgcacaatg
     3841 ccacagggat aaaccatagc aaaccgccta ataacaagaa aaatactaag ctgaagcctg
     3901 aggtcgcgaa tgtgggatat tcatataatg aaacgaccat tgagatggtc atagccaaaa
     3961 agccaaagaa cgttaatttt tttgcaggaa ttttcgtttt gctttgttgc atgaatcttc
     4021 ctcttttcta tttgaatttg tttcaattga gtttgttgcc aaagaagaaa aagtccaatc
     4081 cttcttcttg ttcttctttt gtagtagtga tcgttgtaaa gtgcatcgcc gattttaaaa
     4141 tcactgttgt cagcacatag gcatacacgg cagtaatgat gacaccaatc acttgaatcc
     4201 ctaagaagta ccagctgctt ggattcgtta gtaaatggct gttagatgca aagatcccta
     4261 tcagaatcgt acctgtgaat ccgcccatgc catgaacacc ccacacatca agtgcatcat
     4321 cccattgttt ctttttacga aaatcaacag cagcatgaca gacgataccc gcaatgatcc
     4381 caatcagcat ggcacttttt gcttctacat aaccggcaca aggcgtaatg gctgccaatc
     4441 cagcaacgga tcctgttagt acgtcgacaa aatcaaagcc atttcctttt acttttgcaa
     4501 tgatcagcca agtaatcatc gcaaatgcaa gagcgatgaa tgttgaacca aatgcattga
     4561 ctgcttgttc atctgctcga agtgcaccac cggaattaaa accgaaccag ccaaaccaaa
     4621 gcagtcctgt accgatagca gctgccataa gactgctatg ctgacttctt tctcctaaag
     4681 gaatctttct ttgaccaagt gtgaggatac atgctaaaga gccgaatcca gctgtcgtgt
     4741 ggatgactgc tccaccagcg aaatctctaa atcccatctg atccaaaaat ccgccacccc
     4801 atatccagtg gcaaacaggg aaataaatca gcagattcca aaaaataaca agtataatat
     4861 agccttttaa attcaatctc cctgcaaaag ctcctgtcat caaaggaacg gtaatcacga
     4921 taaacatcag ttggtaaaga aagaacatta aaaatggaat cgttgcacca tgaaacatgt
     4981 tggggaagct tgtaacatgt ctcatcaaaa agaaatctgc cgggtttcca ataacaccgc
     5041 cgatatcccg tccaaaggcc aatccgaatc caccaaatac ccacataatc gttgttatcc
     5101 caacggagag aaaagattga gacatgatcg ttagtatatt attcttccgt gctaatccgc
     5161 gtaaaaaaaa gctagaccag gagtcatcag gcaaaccatt gctgtacata aaatcatgaa
     5221 tgctgtatct cctgtattga taggtaatgt attcattttt ttcgcctcct ttctacgatt
     5281 acgagtataa aagaaggtgt agttgttttt ttcttctgtt tttttgaatt aatacttgca
     5341 tttataaaag acagacaatt aataaaagct tgatgtgttg tgctcttttt cgtttttcac
     5401 acaaataaag acaaaaaata aacggtcttc tttttataga aaaccgttta ttttcgtctt
     5461 tttttatttt taaagatatt ttttcataag gaataaagaa tacttcatat aaaatatata
     5521 aaaaagaacc gcagcgagtg tcgctacggt tctcaaattt gttcttcatt tcaacataag
     5581 tttttcttca atttgcttat aatttacgtg caaagaatga aacgactaat actaaaatga
     5641 ttgcaccgat caatgatgga atgatagcca ttcctgcaat tgttggtccc caagttccta
     5701 gtaaagcttg tccaattgct gaacctacta aaccagcaat gatgtttgcg atgatcccca
     5761 ttgatgatcc tttattcgtg attgctcctg caattgctcc aatgataccg ccgacgatta
     5821 atgcccaaat aaatcccatt ttaaattcct cctaactgac ttcttacttc ttattgtaca
     5881 cgtggttcgt tattttcttt gactttttgt gcacctttgc ctacagcaga ttttgcttta
     5941 tctgtttggc gtgaagcaaa ttgtcctgtg gattttgctg cttctgttac tttgtcttgt
     6001 actgtttctt gatctttttg gtattcttct tgtgttttga tgtctgcaac attcacattc
     6061 acttcgataa catctaaatg tgtcatattg tttacttcag tactgatcaa ttctttgatt
     6121 tggttgtaaa tatcttcgat gtctttaccg tattctacga tcacatctag atccacagct
     6181 acttgtttct tacctacttc tgtattgata cctgctgtta cgttatctgt gttgactaat
     6241 ttttcagcca tatttgagaa aaatccgcca tctaatgtca atagaccatc tacatctttc
     6301 aatgcataac cgatgatttt ttggatgact ttgtcttcat aagtcaattc accattcatc
     6361 atgcggtttt ctcctttttc atttgccaaa actgatccat ttgttgtatt catgtttttg
     6421 ttttccatct ttgtttcctc ctatgattta aaaaattgat caactattcc tgactgtttc
     6481 aaataaaaac cgattcctgc gccaattgct gtcatgatta tgatcaacaa tgtcttgaaa
     6541 aatccaatcg ttaaccataa aacagctagc agtagtccaa gacccccaaa gataataggg
     6601 agcttgtatg ctgaaaatag ttctttcatt atttggccct cctattccac tcgagagtgc
     6661 ttgtagtctc ttgtatcttc ttgttcttca taaccgctgt atgtgactgc cactttgacc
     6721 gtttcttttg ttccgagtac tttagttact tcttcttcga tatcttgcat caatacacct
     6781 gttttcccta ctaatgaaga agttcgtttc aagtctccgt tgacatggat atggattcga
     6841 tttttcgttg aacgtatccg tactttaggt gaatgaatga actcttcttc gtgtaaatgg
     6901 gaacgtacca acccttcgat cgcttttttg tcgattgtta gtttgccatc ttcccgtttc
     6961 ataacgaaag ttcctcttga ctttggatag aaaagaacga ctagcaagat gataatagca
     7021 agaacggcaa atactacagc tgcccagaaa atatattgtt gcatgtagta attcgttaaa
     7081 gtaaagaagc gaaatcgttc caattgttca ggcataatat acggcgcatt gatcaacgca
     7141 atcgctagaa atactgaaag tagcagtaaa ctcatgataa caccgattat ttttaacccc
     7201 ttattcattt tccacctcct ataaacttat ttttaccctg taaataactc taccgacaat
     7261 cacagtatag atagcgaaca gttagcatag catcagtaaa taaagcgcta ccaaacattg
     7321 ctggatcata acggcgtttt attgccagtc tgatactgaa ataacaattg cttacttatt
     7381 ctctatttac ttttgattgc tggctatact taaaggatat tattcaagat taaaaattgc
     7441 aaagattatg ctcagttatt attacaagat tctatttatt tattaaattt tttcggagaa
     7501 ttaaaaaata caataaataa ctttagttac tttaatgcgt tcttacttta tttttatatt
     7561 atcatttttc ttattcactt ctttg
//
LOCUS       DAJSMK010000101         7512 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.105, whole genome shotgun sequence.
ACCESSION   DAJSMK010000101 DAJSMK010000000
VERSION     DAJSMK010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.105"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(304..1650)
                     /gene="gor"
                     /locus_tag="ON488_002294"
     CDS             complement(304..1650)
                     /gene="gor"
                     /locus_tag="ON488_002294"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HCR3232456.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(1784..3037)
                     /locus_tag="ON488_002295"
     CDS             complement(1784..3037)
                     /locus_tag="ON488_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCR3232457.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3043..3966)
                     /locus_tag="ON488_002296"
     CDS             complement(3043..3966)
                     /locus_tag="ON488_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HCR3232458.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4187..6679)
                     /locus_tag="ON488_002297"
     CDS             complement(4187..6679)
                     /locus_tag="ON488_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HCR3232459.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6686..7153)
                     /locus_tag="ON488_002298"
     CDS             complement(6686..7153)
                     /locus_tag="ON488_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HCR3232460.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7289..7362)
                     /locus_tag="ON488_002299"
     tRNA            complement(7289..7362)
                     /locus_tag="ON488_002299"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7326..7328),aa:Arg,seq:acg)
     gene            complement(7420..7493)
                     /locus_tag="ON488_002300"
     tRNA            complement(7420..7493)
                     /locus_tag="ON488_002300"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7457..7459),aa:Pro,seq:tgg)
BASE COUNT         2092 a         1647 c         1204 g         2569 t
ORIGIN      
        1 ttctaattta tttatacaaa gtcacacttt tttaaacatc tgttcttcga tacatttcta
       61 tttcttttaa acatcgatac caatattttg aacttaagag tgcataccaa atggattcat
      121 ttactcttcg tcagttacga agataatcaa aatctccaac ttccctactt atttcgtttt
      181 gagaattatc gaagcaatct tacataaata actaaaaaac aaaaaaccag aaaatcagta
      241 tactgatttt ctggttttac atggtttgtt caataaaaag ctgttggaac tgttaatatt
      301 aaattatcgc atcgttacga attcttccgc tcctgttgga tggatggcta ctgtattgtc
      361 aaagtcttct ttagttgcac ccatcttgat agccacggca aaaccttgca gcatctcatc
      421 gacaccaaca ccaatagcat gtaagccgac gattctttct tcttttccga cacagatcaa
      481 tttcatttcg catttttggc gataatcatt taatgcaaag tacattgggg taaagcgtga
      541 acgataaact ttcaattcat tttcgccata tttttccaat gcttcttctt ctgtcaaacc
      601 aattgttgca attggtggat gcgtaaagac gactgtcgga acaagtttat agtcaagata
      661 agaatctttc tttccattaa ataaacgttc tgataaacgt ctaccagctg cgattgcaac
      721 aggagtcaga tctaatttac cgatcacatc accaacagca aaaatatgtt catccgttgt
      781 attttggtat ttatctactt tgataaaccc ttttttgtcc aattccacat ttgtattttc
      841 cagacctaat ttttcggtat tcggtacacg tccaccggca aaaagtacac aatcaccagt
      901 taaggtttca ccattttcaa atagcaccgt atattcgtca ttgtttttag taatttcttt
      961 agcaatatga tgtgcgtaag tttttattcc agcttcttgg tacatttgga tcaaattgtc
     1021 cgaaagcatt ttatcaaacg ttctaagtgg tcgttctttt cgatatgccc acatgacttc
     1081 actacctaaa ccacgaaata cacctgaaag ttcagccgca atgtatccag cacctaaaac
     1141 gattgctctc ttaggtaact ctgttaattc aaaaaatcca tttgaatcaa ttgcgtattc
     1201 tccaccagga atggtcattt tacttgcacg gcctccagta gcgatcaaga ttttaggagc
     1261 acgataggtt tcaccgttta cttcgatcgt ttgactatcg ataaaagtag cgtaaccttt
     1321 tatagcctcg acatgattgc tatctaatcc tctttgataa gcaccgtgta gaaaatcaat
     1381 atatttttct cgtctttcta ctagaccggc gaaatcaaca ttttttaaat ctgcttggat
     1441 accgtaactt gaggcatctc gttcaattgt ttccaaaatc gtacttgctt gccacataac
     1501 ttttttaggt acacaaccga cgttgacaca tgttccgccc aattcattcg cttcaatcag
     1561 caaaactttt gcgccatgca tccctgctct gtttgctgaa gcaataccgc cagagccgcc
     1621 accaattacg atgtaatcat atatttgcat tttgttcctc cttattgaag agatcaatca
     1681 aaacctttat ttaacgatcc tttttctaca gaaaacaagt gtaacacttt tcttgaattt
     1741 tgtatgcgaa gatgcttaaa acagggatat atcagctttt tccttattta cgttttcgga
     1801 tcatatctcc aggtttcacc ggctgtgcga ctggcatagt taaaatcatc attggatttg
     1861 gtgctcggtc aatggattcg ccttcttcat tatgcataac ttcaacggtt tgactgaaat
     1921 gactgaatcc tggaccataa aattcgattt catctcctac agaaaacaag tttctctgac
     1981 gtatcgtagc aatctgtgtt gcctcatcat aagataatac ttcaccgaca aatttatata
     2041 ctgggatttt acgacgttca ccgaataatt gttcgttttc agttggtgta ttgtagtaaa
     2101 aacctgtagc taattctcgt tgtgctactt tccataactc gtcgatccat tcttgcttgc
     2161 agacatagtt ttcaggatct tccatataac tgtctacagc cgctttatag acatttgaca
     2221 ccgtagatac ataatggatc gatttcattc ttccttcgat cttgaagctg tctacgccgt
     2281 tttcaatcaa ttctggaata tgttcgatca ttgacatatc cactgcactc atcgagaatt
     2341 cttcttccac ttcgcctgta tcagttaaac tgtttcgttc ttgaccaaaa ggcatatcga
     2401 acaatccata cttccagcga caagattgag aacatccgcc acggtttgca tcccgcatcg
     2461 acatatggtt ggacaatgtg catcgaccag aataagagat acacatggca ccatggataa
     2521 atgcttcgat ttcggtatcc gtatttttac gaatctctgc cacttcctcc attgaaactt
     2581 cacgagctaa aacgacacgt tccaaccctt cttctttcca gaattccaat gtctcaaaat
     2641 tagttgctga agcttgagtg gataaatgga tcggcagacc tggggcttct gtcgcacaaa
     2701 tttcgatcaa agctggatca gaaacaatca ctgcagaaat accgacatca cgcaaactgc
     2761 ggaaaaattc ccctgctcca tcttcatttc cttcatgggt gaccatatta gcagcaacgt
     2821 ataccttcgc atcatgttct tttgcaaaag caactccttc agccatttct tcataagtaa
     2881 aattacctgc acggcttctt aaaccatatg cattcccgcc aatatatact gcatctgctc
     2941 cataatggat cgcggttttt aacttttcca gtgttcctgc tggcgctagg atttctggtc
     3001 gtttcaattt tctttttact gtcatttctt tcatcatact ccttatttga tagcagaagg
     3061 atcaatataa aagaatcctg tatctaattc acggttttca ggatgcaatt tactgatttc
     3121 gctagtcatt ttttccgctt tttcttgatc ccagctacct tctaaaattt gtttttttgc
     3181 ttcggcgaat agtcgagtga tgtttacgaa tttttcgcct ggagtaaata atccgtccaa
     3241 tttccatgta cagtaatgat gctgataaag ttcattcaat tcattcgaga gattcagatc
     3301 attgctggca aaaatatgtg tgccatgact atcttcataa atagaataat gtgtctcttc
     3361 ttttttaggt tccgagataa aaagacctct ttcacgatct ttttgttcgt cttgtttcgt
     3421 atagttatag taattctgta gcagtggacg tttggattga tggatgcatg tagcaccata
     3481 cacaagggtt tctacaggaa tatcgagttt ttcttccatc gccttcatct cttcaaaagg
     3541 aacttcacga gcaagtactg ctccaactgc gccttttttc gcccagaaat tgatttgacg
     3601 tgcgctcgtt actaatgttt cagcatcata aatatacggt atacgcaatt caggattttt
     3661 tttcatcgta taaataatac ctgtatcacc aactgtgatc acatctacgt ttatttcttt
     3721 taaaaaagcc aaatattcag gtacattttt cattttttca ggatgaatga tcccatttac
     3781 agcaatattc gcttttttac catacttgtg tgctaattct accaattgtc gctgttcttc
     3841 tcgtgtaaat gaagcaggca gacgcaatcc aaattgctct tcaccgaaat atagtgtatc
     3901 tgcacctgca gcaagcaact gttctgcttg ttcaatagtt tctactgtgg ttatgagttc
     3961 gatcataatt ttctcctcct acaacttcat aatagtagca tagctctaaa aactttccaa
     4021 tacttcttct atttaaagtc ggatttttga aaattatttc acaaaaaatc aaaataaagt
     4081 tcgatatatt ctgtccaaat ataaaaagag attgtgacaa aaatcttgtc acaacctctt
     4141 aatcaagtct tactattata aaaattcagc tacacaggcc aagtaactat agggaaccta
     4201 ctgtttcctt tttaggtccg cgaacattca atgtgatctt accttttgaa gcacctactg
     4261 ttacgtggtc acctaaacga atttctccgc caagcaaagc ctcgctcaat cgatcttcaa
     4321 tttctttttg aagtgcgcga cggattggac gtgcaccata ttcaggatca aatccagctt
     4381 tcccgatcac atcgattgca gatggtgtga ttttcacttg aatatcttgt tctttcaatc
     4441 gtttgataat cgctttgctc atgatttgga cgattgtatg gatttcatct ttactcaatg
     4501 aatggaagac gacagtctca tcgattcgat tcaagaattc aggtcggaaa gctttcttta
     4561 actcttctaa gatacgtttt tgcatggctt tgtgatcttt agtaacatct tggacattga
     4621 atccgacatt tttttcttct cgaatttgtg tcgctccgat atttgaagtc ataatcatga
     4681 ttgtatttct aaagtccact tttctacctt tagaatctgt taaatgacca tcatccaata
     4741 cttgcagaag taaattgaaa acgtctggat gtgctttctc cacttcatct aagagaatca
     4801 ctgaatatgg tttttgacga attttttctg tcaactgtcc accttcatca taccctacgt
     4861 atcctggagg agacccgatt aatcggcttg tactgtattt ttccataaat tctgacatat
     4921 caacacggat cagggcatct tcacttccaa acatgacttc tgaaagtgct ttggccaatt
     4981 ctgtttttcc gacaccagtt ggtccaagga acatgaatga accaattgga cgatcaggat
     5041 ctttcaatcc gcttcgtgca cggcggatcg cacgtgaaac tgctttgaca gcctcatctt
     5101 gaccaacgac acgttcatgc agaagtcctt ccagttctaa caagcgttcg ctttcttttt
     5161 tctccaactg ctgtagaggg acaccagtcc actccgatac aactgtagca acatcttctt
     5221 ctgttacacg atcagaataa ccttgctcct gttttgcttc aattgcagaa actttttgca
     5281 gctttttacg tagtgctttt tcttgtctgc gtaattgagc agcattttca aagtcttgtt
     5341 tttggatcgc tgcttccttt tcttgtacta gttcatcgat ttctagtttg atcacagttg
     5401 attttgttaa gtgatcggtt tgatccaaac ggactttcgc tgctgattca tcgatcaaat
     5461 caattgcttt atcgggtagt tgacgagaag tgatataacg aacagaaaga ttgactgctg
     5521 ctcgtacagc ttcatctgtg atctccactc catggtgctc ttcatatctt gtacgtaatc
     5581 cttgaagaat cacttctgct tcttcaggag ttggctcatc tacttgaatg cgagcaaaac
     5641 gtcgctctaa tgcagaatct ttttcgatat atttttgata ttcatctagg gtcgttgctc
     5701 cgatcgtttg taattctcct cgagctaacg ccggtttcaa gatattcgaa gcatcaattg
     5761 ctccttctgc tccacctgca ccaattaagg tatgcaattc atcaatgaat aagattactt
     5821 gaccatcatt atagatttcg tcgatgacct ttttcattcg atcttcaaat tcaccgcgat
     5881 atttcgtacc agcaaccaaa gatcccatat caagcatcat caggcgcttt tcttgcatgt
     5941 cttctggcac ttcacctaaa atgatttttt gagctaaccc ttcagcaatg gctgttttgc
     6001 ctacaccagg ttcacccacc agtacagggt tattctttgt ccgtcggcta agaatctgga
     6061 taagccgttt cacttctctc gaacgaccaa caactgggtc cagcttgttt tcttttgcta
     6121 atttcgtcaa atcacgtgct aatgaatcta gcgtaggtgt tccttgcggt gtttgccgtt
     6181 tatcttgtac atttacattt ctacgacgat tcattccttt tccagcagaa tcaccagcta
     6241 gccccatttt ttgtttcaga acttgacggg cttttgaaag gctgatacct aagttgatca
     6301 tgattcgagt agccatgata ctttcatctt ttaataagct catcaaaata tgttctgttc
     6361 caactttttg agaaccagtt ttcttcactt cgctgctagc taaagcaaaa acttgtttca
     6421 ttcttggtga atatggaaga aagactcctt tagggtaaga acggatacca ccataaccaa
     6481 tcagatgttc aatttcttca taaatttccg tttcattcaa atccatttca cgtaatactt
     6541 ttccagcaat tccattttgc tcgaccacta aggctagtaa aacatgttct gaactaactg
     6601 attgatgttt caaccgtttt gcttcttctt gtgcaatttc taatactgct tgggctcttt
     6661 cagtaaaaag ttcttccatc taatctcact tcccatcttc ataacttaaa cgttccagaa
     6721 atgctcggag aatccgagca cgtgtatgat cttcatattc attgaaattc aatgtgtttt
     6781 ttgcaattgc actcaacatc aagtttcctt ctttttttgt aattatttgg tcttcataaa
     6841 gtttttgaat aatagcaaaa gcatttttct cactgattgt atcatcaaat aactgattta
     6901 tctgctcaag taattgtttt ttatctgaaa tccttacttt tgcaattcgt atataaccac
     6961 caccaccacg tttgctttct actagataac cacgttggat ggtaaaacgg gtattaatca
     7021 catagttgat ttgtgaagga acacagttaa agaggtctgc catttcaatc cttcgaatct
     7081 cgatcatttc actattttcc agaattttct ttatatatga ttcaattaaa tccgaggtat
     7141 tctgatgtgc catcttattc attccctttg actaatattg accttaatta taacgaattt
     7201 gataatagaa agaaagaaga acgctttttg ttaaataaat cctttagaat caacaaaaaa
     7261 aaatacggaa tatactattc cgtatcgacg cgcccaagag gagtcgaacc cctaaccttt
     7321 tgatccgtag tcaaacactc tatccagttg agctatgggc gcatattcaa tttaaaaaaa
     7381 ttataaatca tttgaaaaca aaaagcaaga taaaaaaaat cgggaagaca ggattcgaac
     7441 ctgcgacccc ttggtcccaa accaagtgct ctaccaagct gagctacttc ccgtttaaaa
     7501 aataaaaaag ac
//
LOCUS       DAJSMK010000102         7276 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.107, whole genome shotgun sequence.
ACCESSION   DAJSMK010000102 DAJSMK010000000
VERSION     DAJSMK010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.107"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(170..3319)
                     /locus_tag="ON488_002301"
     CDS             complement(170..3319)
                     /locus_tag="ON488_002301"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HCR3232461.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKTGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLTGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDNLIHA
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3332..4543)
                     /locus_tag="ON488_002302"
     CDS             complement(3332..4543)
                     /locus_tag="ON488_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCR3232462.1"
                     /translation="MSNDTQPEIRFPGFTDDWEQRKLGDFVVDYVEKTSVQNQFPMLT
                     SSQQKGIVLQEDYFANRQVTTENNIGYFVLPRGYFTFRSRSDNDVFVFNRNDIIDRGI
                     ISYFYPVFTLKSADSDFFLRRINNGIQRQLSIQAEGTGQHVLSLKKFKNIVAMFPSEE
                     EQQKIGTFFKQLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWE
                     ERKVFEISKVTYGGGTPKTNTKEFWNGNIPWIQSSDLEINRLFNVSPKKKITNEAVKK
                     SAAKIIPPNSIAIVTRVGVGKLALMPFEYATSQDFLSLSELQIDSYFGIFSLYSMLQK
                     ELKNIQGTSIKGMTKSDLLEKKVTIPKKYEEQQKIGNFFKQLDDMIALHQRKLDLLKE
                     TKKGFLQKMFV"
     gene            complement(4533..6128)
                     /locus_tag="ON488_002303"
     CDS             complement(4533..6128)
                     /locus_tag="ON488_002303"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCR3232463.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKKLLEAIS
                     SLQTTPENEAWLQGALEVFKHEQ"
     gene            6253..7038
                     /locus_tag="ON488_002304"
     CDS             6253..7038
                     /locus_tag="ON488_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SinI family restriction endonuclease"
                     /protein_id="HCR3232464.1"
                     /translation="MPNKNRTFESILNEGLTTEPASIIFDEVIDDVEDSKYHKNLKEL
                     FYFALNNGPSLFTGISVPDSDNPLIMAKIYLTKWCNKYIRDRNNPALKKPLKTFGEKD
                     AALTTRVAANANIDDQKVLNDYLRGHFLYMSAENMNGSILEEYLAEVLEPEGWIWCAG
                     SVYRAVDFCYLGTSPILLQVKNKYNTESSSSSAIRVGTTIRKWNRLNKSTKISGLDSP
                     IPNWKALIEMTEASKELAAKLTENSYLAYINEKSTRELWTLDD"
BASE COUNT         2134 a         1433 c         1198 g         2511 t
ORIGIN      
        1 tgcaacagaa ccggtaaatg aatgaaaaag atggaagaat cattattcaa tagctttctt
       61 aaatactccg ttataaaatg tgaacaagta aaaagacatc tatccctatt ttctacactt
      121 ccactttact actatctttg aatcgtacaa ttttcttaac tcttctcgtt tacctcaatt
      181 cattttcaag tggaatcaac tcatcatcta acattttacg ccatgctcgc ttcatttctt
      241 gtgggtattt aaatggtttc gcttctggat gtttggcttt atatccttcg taatccttac
      301 tgttgataat tgctttcata ttaggaattg gatcttcacc tggcatatat tgcagattag
      361 aagcatgtaa ttctttctca gaaacaaacc actcattgga aaaggcatga atcaaattat
      421 cacttgcttg tgtaaaatag cgacgtttaa tgacaaagat atcttcatta ctatctaaag
      481 tccccacatc aaatgcattt aaaatttgtc ggtaaacttc tttgactcct tctgttttat
      541 tcaatttagc caaagctttt tcaatttctt ctcgtgcatc tgaactattc gcagcataag
      601 ttcctagtaa ttgatcaata taagttgaat caatatcata caacttagtg gtattttcac
      661 tataaaattc gatcgttgaa aaatcttctc cttctttttc tggttcttcc tctattaatg
      721 aacccttcac ggtctcgtac acgccaattt gttcttccaa aagttgaatt tgattgttca
      781 aagttggaga tttcaccatg tcatcattgt aatcgtcata agtcactaac gattcatacg
      841 cacgattcaa ttcttgaaat gctttgacgt actcgatacg gatttcaagt ggcgtatgtt
      901 catcaatgga ttccatggat gaaacctctt ttaacttacc atatgcttgt ttgaatcttt
      961 ttttggattc ctgataactt ggataaatca aacctgattc ttcttttgct tttgaataca
     1021 gttttgtcgc atcctcgaca ttcttctcca ttgtcgctgg cttacgaaac gtcacaatca
     1081 atccttttgt cttatcagga tacgtacgat tcgtacgtga aaaagcttgg atcaatcctg
     1141 catactctag attacgatcc acaaataggg tttgaatcgt aggggcgtca aaacctgtta
     1201 atagacgatc cactacaatc gctaaatcga tttgtttccc aaattgtttg aattccgctc
     1261 tttttcgtgc caaacgatta ttgatgtctc cgttataacg ctcaatgtct gctaatgacc
     1321 aggaagtatc ataatactga ttatattcct caataatttt ttgcatttct tcttgttggg
     1381 cacttgaatc tcggctattt tcttctaatg aataggtaat agcgattcgt ggaaaatcag
     1441 gatcctccat cgttcgtcct tcacgaatga gctgattggg aaactctttt gttaaccaat
     1501 caggctcttt cgtcatctct ttgatggccc gataatactt tttggccatg tcaatggaac
     1561 tcgtggttaa gattgcagat ttcgttggcc tgccatttcg aaaatcaaat tttgtatagg
     1621 cattatctgg acggaacatt ttatgaatga ctttttggat atgttcatct gcttcaaaaa
     1681 cagctgggtc caaataactt tcttttttga caggttccat ttgatcaatc atacgattga
     1741 tctgttctga tgaatactct gcatatgttt ctacttcttt taatttccga tagattttat
     1801 tctctagtga agtcggctcc acggtgtttt catgctctac ttgaaatcct aaaaccgagc
     1861 catcttctaa tgcattcttg atggtatagg tatgcaagac ctctccatac tgatcatggg
     1921 tcgtacgtgc caattgccct ttggcttgtt tccgattctc agggaaaatc ggtgtacctg
     1981 taaagccaaa ccaagtggat ttcggaaaca tttttttgat ttcttccata ttttcagcac
     2041 ttaacgctcg atgacactca tctactacaa acacgatatg ttgccccgtt aatttttgga
     2101 agcgattggt tccttttttc tcttcttgtt tctttgcata tttcaacgct gcatctagct
     2161 tttgacgggt tgtaatgatc acaacatttg cattggcatc tgccaacagg gtttcactta
     2221 attctttggc acttcctgtt cccacgatca agctattcgc tttggcatta ccagaagaaa
     2281 tcccagtatt aaactccgaa gcaaatttcg taaactctgt ggtggtttga ttatctaaat
     2341 ctttgcggtc cactaacatg atcgtccgat cgatccccgt ttttcgtgct aaaagcttag
     2401 tagatacaaa actagtcaac gtttttcctg aaccagtcgc atgccacaca taccctgatt
     2461 gatgtttatt tgcagcaata aacaaggctt gaatcgcatg tacttgataa ggatgtaaca
     2521 ccatgaggat tttattgtct tgatcttcac tgacaatcgt ataatccgca atcaagcgat
     2581 gagcatccgg gatatttagc acttgtttgc aaaactcata taagttttct acctttttat
     2641 tatctttcgt tcgccaacta aataaaaact taggatgcaa atcctttggt aaggcatttg
     2701 caaaataccg agtggtttgt tcattggaaa ccacaaacaa ctgtaaggtc gaaaagatat
     2761 tgttccgaaa cataccttct tctgcatatt ttttgatttg gttaaacgcc tgataaaaac
     2821 catcttttgc ggttacttgt ttcagctcga tttggacaat cggtaatcca ttgatcagta
     2881 aggtgacgtc aaaacgtcga tcccgtgctt ctatgttact tccacgtttt gcaatttgat
     2941 ggaccacttc ataagtagag attcctccac caatgtcttg attggaataa agaatgagcg
     3001 agacagaacc caattgcgga tcttcccgtt caatcgtgat ccgagccatt ccattttcac
     3061 cttttaacca tttcgcagca tcaaaggggg ttttcgttcg tagcaataat tccgttttga
     3121 tcgtttcaaa ttctttatcg gtcaaaggaa aatcattcag ttctgcttga ttatttgaga
     3181 tgattttttg acgtaaattt acccaaaggt cttcttctga ttttagatcg ggacgatacg
     3241 tccactgatt atgtccttcc cccagtacac gaatcaactg ttcttcgact tccgcttcct
     3301 cacggtgact aattttcatt cttcttccct cctagacaaa catcttttgt aagaagcctt
     3361 ttttcgtttc cttcagcaaa tctaacttac gttgatgaag agcgatcatg tcgtcgagtt
     3421 gtttaaagaa gttaccgatt ttttgttgtt cttcatattt ttttggaatg gtcacttttt
     3481 tctctaataa atctgactta gtcattcctt taatagatgt tccttgtata ttcttaagct
     3541 ctttttgaag catagaatat aaagagaaga ttccaaaata tgaatctatt tgtaactctg
     3601 aaagtgataa aaaatcttgg ctagtagcat actcaaaagg cattaatgct aatttaccaa
     3661 cccccactcg tgtaactatc gcaattgagt tagggggaat aatttttgct gcagattttt
     3721 taacagcttc attcgtaatt ttctttttag gagaaacatt aaataatctg ttaatttcta
     3781 aatcgctact ttgaatccat ggaatgttac cgttccaaaa ttcttttgta ttagttttag
     3841 gagtaccacc accataagta acttttgaaa tttcaaaaac cttacgctct tcccaatctt
     3901 ccgtaaaacc aggaaaacgg atttctggca cttttgctcc gttttcaggg aacatttttt
     3961 gtaagaatcc ttttttcgtt tccttcagca aatctaactt acgctgatga agagcgatcg
     4021 tgtcgtcaag ttgtttgaag aaggtgccga ttttttgttg ttcttcctca ctaggaaaca
     4081 ttgctactat atttttaaac ttttttagag acagaacatg ttgacctgtt ccctctgctt
     4141 gaatagataa ttgtcgttgg attccattgt taatacgtct taagaagaag tcggaatcag
     4201 cagattttaa agtaaataca ggataaaaat agcttataat ccctctatca ataatgtcat
     4261 tacggttaaa cacaaacaca tcattatcac ttcgactacg gaacgtgaaa tatcctctag
     4321 gtagtacaaa gtaaccaata ttattttctg tagttacttg ccgatttgca aaatagtctt
     4381 cttgcaaaac tatccctttt tgttgagatg aagttagcat aggaaattga ttttgtacac
     4441 ttgtcttttc aacataatct acaacgaagt cccccaactt cctctgttcc caatcatctg
     4501 taaatcctgg gaaacggatt tctggttgtg tatcattgct catgtttgaa cacctccagc
     4561 gcaccttgta accacgcttc attttcaggt gttgtttgca gggaagagat agcttctaaa
     4621 agtttttttt ctagcacttg ctgttcttgt cgtatcttct tgatgtcatt tccgacatga
     4681 accatatcaa ttggttcttc ttcttcgaaa gtatctacat agcgtgggat atttaagtta
     4741 tagtcatttt ctttgatttc atcaaaggtt gccaaatgag cgtatttctc gacatctttt
     4801 ctttcagcgt aggtttcgag gattttttga atgttttctt ccgatagttt attttgattt
     4861 ttccctttaa caaattcacg actagcatca atgaataata catctcgagt ttgacgattc
     4921 ttcttcaaca caatcaccgt cgttggaatc gatgtcccaa agaacaagtt cgcaggcata
     4981 ccgatcacag cataaatact gccatcttct agtaattttt gacggatgac cccttctgca
     5041 gcgccacgga ataaaactcc gtgtggtaag acgatggcca tggtacctgt ttccttcaaa
     5101 tgatagaacc catgaagaag aaacgcaaaa tctgctttgg attttggcgc taatttccca
     5161 taacgattaa accgagaatc atctaagaaa gtcgtatctg ctgaccaatt agccgaataa
     5221 ggtgggttca ttactactgc atcaaatgtg taaggttcat ctgttggcca gtccttattc
     5281 aacgtatccc cattgcggag attcatttct tcggcgtcga caccatgtaa aatcaagttc
     5341 atttttgcta gattgtatgt cgttgtattt agttcttgcc catgatattt aacgttatct
     5401 gggtgtgtta agtagttacg tacgtttaac atcaatgaac ctgaacccat cgttggatca
     5461 aaaacactaa agaatcgtcg ttccttttga tcgagcgtta cgatttgcgc catcatatca
     5521 gaaaccatat gaggtgtgta aaattctccg gctttcttcc ctgcttctga agcaaattga
     5581 ctgatcagaa actcatacgc atccccgatc acgtccccat cgtgttctaa aacatctaca
     5641 tcattcaatt tcttgatgac ttcggtaatc gtcacatttc gttgttgctc atctgttcct
     5701 agtttttttg attggagatc cacatcatca aataacccat taaattgatt gtaggtagat
     5761 gccaattgca caaaggcttt gtttagatcg ttcaattgga acgttgcttg ttttgcttga
     5821 tccgctaaga cgttgaaaag atactctggt gcaattgcat atcccaaaat atcaacgatt
     5881 gtggcaatca gatcttcttt tgattcttca tctgaaagta attcacgata caacattgtt
     5941 tgtttgctta ctgtgtcata ttcctctaag gattcatctg ctaaaagaac cacttgttcc
     6001 aacaatcgat cggataaata tttatagaaa atcagtccca ataaataatt tttatattct
     6061 gacgcatcca ttttactacg gagattatct gccgcactaa ataatttttg atttaattct
     6121 gcacccaaaa agatacactc ctatctctta tttaaagttg ctatataccc tcttatttta
     6181 gcatactccc ttttagaaaa agcaaaaaaa aaagaaaaaa tcttattctt gataacaagc
     6241 tacgtgacgt atatgcctaa caaaaataga acttttgaat caatcttaaa tgaaggttta
     6301 accacagaac cggcatccat tatttttgat gaagttatcg atgacgttga agatagtaag
     6361 tatcataaaa atttaaaaga acttttttat tttgcactca acaatggacc aagtttgttc
     6421 actggtatat cagtacctga tagtgataat ccattaatta tggcaaaaat ttacttaaca
     6481 aaatggtgta ataaatacat cagggatagg aataacccag cattaaaaaa acctcttaaa
     6541 acatttggcg aaaaagatgc tgctttaact actagagtag cagcaaatgc taatattgat
     6601 gatcaaaaag tattgaatga ctacttgcgt ggacattttt tatatatgag cgctgagaac
     6661 atgaacggaa gtattttaga ggaatattta gccgaagtgt tagaacctga aggttggatt
     6721 tggtgcgccg gctctgtata tcgagctgtt gatttctgtt atttaggaac ctcaccaatt
     6781 cttttacaag tgaaaaataa atacaataca gaaagcagtt cgagttcagc tataagagta
     6841 ggaacaacaa ttagaaaatg gaatcgttta aataagtcga caaaaatttc tggtttggat
     6901 agccctatcc ccaattggaa agcattaata gaaatgactg aagctagtaa ggaactggca
     6961 gctaagttaa ctgaaaatag ttatttagct tatattaatg aaaaatccac acgagaatta
     7021 tggacactcg atgactaaca atatccttat tagtatctat ccacgataca tggaaaaaat
     7081 tataaacaaa caaaaaaact ttgaatttag aaatttctat cttacctcag atccttataa
     7141 tatcttttgg atttacgaaa caatccccac caaagcttta aagtataaat tgattgtaaa
     7201 aaatccaatt actaaactta agaaaaatca acactacttt ttaggagacg atgagtttga
     7261 acaattagtt taaaag
//
LOCUS       DAJSMK010000103         7027 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.108, whole genome shotgun sequence.
ACCESSION   DAJSMK010000103 DAJSMK010000000
VERSION     DAJSMK010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.108"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(158..616)
                     /locus_tag="ON488_002305"
     CDS             complement(158..616)
                     /locus_tag="ON488_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3232465.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(629..1960)
                     /locus_tag="ON488_002306"
     CDS             complement(629..1960)
                     /locus_tag="ON488_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HCR3232466.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1971..3413)
                     /locus_tag="ON488_002307"
     CDS             complement(1971..3413)
                     /locus_tag="ON488_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3232467.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(3400..4164)
                     /locus_tag="ON488_002308"
     CDS             complement(3400..4164)
                     /locus_tag="ON488_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HCR3232468.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4268..5143)
                     /locus_tag="ON488_002309"
     CDS             complement(4268..5143)
                     /locus_tag="ON488_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3232469.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5398..5482)
                     /locus_tag="ON488_002310"
     tRNA            complement(5398..5482)
                     /locus_tag="ON488_002310"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5446..5448),aa:Leu,seq:caa)
     gene            complement(5500..5571)
                     /locus_tag="ON488_002311"
     tRNA            complement(5500..5571)
                     /locus_tag="ON488_002311"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5537..5539),aa:Gln,seq:ttg)
     gene            complement(5581..5653)
                     /locus_tag="ON488_002312"
     tRNA            complement(5581..5653)
                     /locus_tag="ON488_002312"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5618..5620),aa:His,seq:gtg)
     gene            complement(5715..5799)
                     /locus_tag="ON488_002313"
     tRNA            complement(5715..5799)
                     /locus_tag="ON488_002313"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5763..5765),aa:Leu,seq:caa)
     gene            complement(5820..5890)
                     /locus_tag="ON488_002314"
     tRNA            complement(5820..5890)
                     /locus_tag="ON488_002314"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5856..5858),aa:Cys,seq:gca)
     gene            complement(5936..6007)
                     /locus_tag="ON488_002315"
     tRNA            complement(5936..6007)
                     /locus_tag="ON488_002315"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5973..5975),aa:Gln,seq:ttg)
     gene            complement(6019..6091)
                     /locus_tag="ON488_002316"
     tRNA            complement(6019..6091)
                     /locus_tag="ON488_002316"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6056..6058),aa:His,seq:gtg)
     gene            complement(6094..6167)
                     /locus_tag="ON488_002317"
     tRNA            complement(6094..6167)
                     /locus_tag="ON488_002317"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6133..6135),aa:Trp,seq:cca)
     gene            complement(6174..6254)
                     /locus_tag="ON488_002318"
     tRNA            complement(6174..6254)
                     /locus_tag="ON488_002318"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6218..6220),aa:Tyr,seq:gta)
     gene            complement(6256..6331)
                     /locus_tag="ON488_002319"
     tRNA            complement(6256..6331)
                     /locus_tag="ON488_002319"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6296..6298),aa:Phe,seq:gaa)
     gene            complement(6367..6439)
                     /locus_tag="ON488_002320"
     tRNA            complement(6367..6439)
                     /locus_tag="ON488_002320"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6404..6406),aa:Asp,seq:gtc)
     gene            complement(6449..6521)
                     /locus_tag="ON488_002321"
     tRNA            complement(6449..6521)
                     /locus_tag="ON488_002321"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6486..6488),aa:Val,seq:tac)
     gene            complement(6537..6608)
                     /locus_tag="ON488_002322"
     tRNA            complement(6537..6608)
                     /locus_tag="ON488_002322"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6573..6575),aa:Glu,seq:ttc)
     gene            complement(6623..6712)
                     /locus_tag="ON488_002323"
     tRNA            complement(6623..6712)
                     /locus_tag="ON488_002323"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6676..6678),aa:Ser,seq:gga)
     gene            complement(6752..6825)
                     /locus_tag="ON488_002324"
     tRNA            complement(6752..6825)
                     /locus_tag="ON488_002324"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6789..6791),aa:Asn,seq:gtt)
     gene            complement(6835..6950)
                     /gene="rrf"
                     /locus_tag="ON488_002325"
     rRNA            complement(6835..6950)
                     /gene="rrf"
                     /locus_tag="ON488_002325"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2117 a         1552 c         1150 g         2208 t
ORIGIN      
        1 cctgaaaata agttttctaa atcataggag caacaaaaaa attcgataat taacaaaaat
       61 caaaatgatt aaatctagtg attgaaacat atcatttcaa aaaaattttg taaattcacc
      121 cataaatatc accctattta acttttttca tcgtacacta aaattcaaaa caactatctt
      181 taatctttac ttcttggttt tgttttaata aatttccttc aaaaatgcct ggagaaacta
      241 caatgatcac cgtatctttt tgtgcttgct ccaacttctt caaatctata atagctaaca
      301 gtgtcccttc ttttacctcc tggttacttt caacccgtat ctgaaacgga cttccttcga
      361 gttcaactgt atctaaaccc atatggatca gtatttttct gccagattca ctttcgatcg
      421 ttatggcatg tcgggtagga aatatattat cgattattcc tttaactggc gcatggatat
      481 atccatcatg attcgttata gcgtatccaa ctcctatcat ttttgaagaa aagacctcgt
      541 cttttactgc tgttaatgga ataatttgac cactagctac agcttttaga atgtttcttg
      601 ttttaaagaa atgcactttt tatcacctct actttaatgc tggccaatat tttttgttta
      661 ctttgatcat ttcatctagt attttttttg cgactctggc atttggtacg gtttgattca
      721 atgtaaatgc ttgtaaagct ttttgataag aaccttcaaa gtaagcatct actagtaact
      781 tctctactgc aacttgtgcc tccatcaatc ctttatgaaa atcactgatt ggttttctta
      841 gtgtaattgg ctccacacca gttgcaccaa catatgccgg tatttcaaca actgcatctg
      901 accgtagatt cggaatcgcc ccttgattag gaacgattag cataaagcga cgacgatcat
      961 cattcaacaa ggaaatagct atatcgacga tatattgtcc atgctcccca aaattaaagt
     1021 tcaatacttc ttccacaata ccgcggcgta ttttatcagc catttctttg gtatttttct
     1081 ctcgtccatc catgaccata ttagcacgtg tatactcttt gtcagtatgc tcaacgacca
     1141 tatcaggata taagtaatac tctaagtaat tattcgggat attacttgga aaatttttcg
     1201 tgatgactga catcatttga aaggtttttt gccaagtttt atctcctata ttaaaatcgg
     1261 cgacttgcat ttcttttgtt attagttttt caataatctc tggcataatt tctcgttgca
     1321 attctttatc ataaatcgat gtataccagc caaagtggtt taaaccataa tacgtaacga
     1381 tccaattctt acgatcataa ccgtaattca ctgcaatcgt ttcttcaatt gaaatagtca
     1441 tatcacaggc attaatcatt tttacattcg gatatttacg acgaacagct tcagaaacga
     1501 tcgactctgg atttgtataa ttcaaaatcc atgctttggg ggcatagtct tgtatatgat
     1561 cgacaatttc caataaacct ttgattgagc gcatcccata agcaaatcct ccgagtccac
     1621 acgtttcttg tcctactaat ccatgtttaa gtggaatctt ttcgtccttt tctcgcatct
     1681 ccaatcctcc aacacgaatt tgtgagaaaa caaaatcgca tcctgtaaaa gcaagctttg
     1741 gatcatccgt tgcacgaatg cgaatatttg aaaaaccttt tcttttcagc ataaatttaa
     1801 caatcaagta catatccata tttctttctt catcaatatc atataaacgt atttcagata
     1861 atggcaaccg tttttcattg ttcaaaatgg cttgaacgat tcctggtgta tacgtactcc
     1921 cgcctccagc tatagtgata atctgttttt tcatcatcat cttttccttt ctattcttct
     1981 aataatttat tgaattctgc cataacataa gtcacttcta agccgatgat aatttgataa
     2041 tttttttcag ttggtttaat gatcccgctt atccctaatt gcttgattcg ctgttcctcg
     2101 accatggtgg gatccactac ctctacccgt aggcgtgtat tacaactata gacatccagg
     2161 atattggctt ttcctccaaa cgcttgtagc atttttgttg ccatatattc ataattttta
     2221 cttgctaacc ctaactctgt ttcttctaag gttacttcat tgccaaactc tgccttagct
     2281 tcacgtccta atgtctgaat gtttctctta ttgatcaaat aataaaaagt aacgtaatac
     2341 aaggcaaaaa agaaaattcc gattggaaga atcaaaatag cattggtagc gattcgaaaa
     2401 ttgatgagat aatcaacaat acatgctccg aatgtaaaac caattcgtat attgaataag
     2461 taacagacaa tccctgctaa accggcaaaa agtgcatgga tcacgtacaa cataggagaa
     2521 agaaacatga aactaaattc aacaggctca gtgatatttg caataaatga agttcctgca
     2581 ccgcttccca tgattccttt gaccatctct ttattttctt tataagctgc tttatagata
     2641 gctagacata tagctggtat accaaacatc attactacaa aaaaaactga taaaaacagt
     2701 ccagcctgag gatctccgtt gataaagcgt gtcatctctc ctctgaaaac ttccttgcta
     2761 ggagatgtat agcttcctaa atcgtaataa atatacgtat tcaacacatg gtgcagtcca
     2821 aaggggatca gcaaacgatt caaaaacata aatatcccca cacctaatgc tcccatatca
     2881 acgagcagtt ttgcaaaatt atcaatccca atttggatga gcggccagat aaagcccaaa
     2941 aaaacagctg cgattgtttg tagaatcatc accatagtca atgggaattt ttcgcccgca
     3001 aaataagaaa aaactactgg taatttttgt tctttaaagc gattatacgt ccatgccgct
     3061 actaaaccgg aaataattcc accaaaaatc cccatattca cttctgggtc cataatttct
     3121 aagccttttt tcaaggtagc aatcgctaaa aaaccagtaa gtgcaggtat tcctttgtcc
     3181 ttatttttga caaaaccgat tgcaactcct atagcaaata agatatccaa gtttccaaaa
     3241 acggcatttc cagctgcacc aattactggg atgttcagca tatcgtcagc tgataaacgc
     3301 atgatcaatc ccgctaatgg catcgctgca actggaagta gcatcgctct tccaagcttc
     3361 tgcacatttg atttaacatt catttttatt cctcctctat taaatatcct catatgttac
     3421 taactcaatc aaaggatcat ttttcacttt ttgagcaaat gctgaatgaa ttaaaaattc
     3481 gacttggtgg gtacgaggat acacaaaact tgaaccattt aacaattcct gatccaaata
     3541 cgctgcgtga cacatgactt cgatcgtttt atcttctctc aatatcatga gtaaacttgc
     3601 caaatattct tccacactcg tattgatttg tcgttttttt tcatcagttt ctcctacgac
     3661 atcgaaacaa ggctcaaaat aatcgacatg acgaacttca tcttttcgtt caaagttgct
     3721 ccgaaccggc aaatcatatt tttttgctaa tgtaacaact acctcctgat tttcatccaa
     3781 agtatgagta tgatgatgac tgtctaaatg agttggtatg atccccgcat gataaatttt
     3841 ttgaatctga gcattccatt cctgatacag ttgatctttg tcaatgttaa atggatgctg
     3901 ataataagat aaggatctga actctccgct ttcgataaga gtatcgacag ttttgaggag
     3961 tggtttgcca cacgtcaatg ttaaatggac tcctacacct agcctaggca tttcctttct
     4021 tagtttcaca gcatgctcga aacccggcat atttgccatc aatgtagttg atgtcaaaat
     4081 tcctcgctga taagcatcca taatcccata attcacacca tggctatagc caaaatcatc
     4141 cgaattaaaa atcacttttc ccatttcatt ctccttcttt tttctactaa aataggcgca
     4201 accaaataat catagtccat ttactatgtg tcatttggtt gcgcctatag atagttacgc
     4261 ccttatttta atagattctt gctagatgaa ttgccaaata gatgatttca ttttcttgaa
     4321 tggcaagttg aaattgctgt tcgatgatat ctttaatctt tagtgctgta caatacgctt
     4381 tgctatgttt aaatgtttca gtaaaaaaac caatattttc tactggcgtt tcttcctgat
     4441 aaatcaagcg tttaaccagg aatttgatat gaaccattaa gcgatgataa gtcagtgatt
     4501 ctttatcata aacgtttgaa taggattttt ctagatggga caaaatcgtg gtcgtcattt
     4561 ctactatttt taagctcttt aaactattag gctctcctag ctcagcatta atgatatgca
     4621 tagtgatgaa tcctacttca tttgacccta actcggtttg atatcgatga ttgattcgct
     4681 cgaccacttc tactgctata tcatattcat ttggataaag gaatctcatt tctggcaaca
     4741 taattgctgt gacatctcta tcttctcttt ttcgttgaat agcaaaataa atatgatctg
     4801 tcaatgtaat atagatattt gaatctaatg gagaggagat cctagctgtt atcagttcaa
     4861 tcacttcttc cgcaaaatcc ataaattcga ttggaatctg cgagactatc tcactgaatc
     4921 gtttgatctt ttctttagaa tctaatacaa ataatttgtc agcatcctca acatcaaatg
     4981 gcttactcac tttagcagaa aagccaatcc ctttccccat cgcaattttt tctattccat
     5041 cgtcatcgat caatacagca ttatgattca gctttttcat cacatacacc gttaattcac
     5101 ctcctctata tgataaaaca aaacaacttg cagactcctt catacatatt tttgtctcca
     5161 aacaattttt aaagacaaaa aacgacctaa gaaagaaccc tttcttaggt cgtgcctaat
     5221 tgaatagtag caccctacat aatttacaaa aatagtttaa cacataataa aagcgttatc
     5281 aatatctttt ttactcgttt tatgataata cttgtatcga attgatttgg aggtaattac
     5341 ataaaaacaa aaaaaatata gcaactctct ataagaaagt tgctatattg ataattatac
     5401 cggcggccgg ggtcgaaccg gcacgtcctc aacggacact ggattttgag tccagcgcgt
     5461 ctgccaattc cgccacgccg gcaaatttaa aaataataac tggggtagct ggattcgaac
     5521 caacgcatga gggagtcaaa gtcccttgcc ttaccgcttg gctatacccc aagaataaag
     5581 ggcgaatgat gggaatcgaa cccatgaatg ccggagccac aatccggtgc gttaaccact
     5641 tcgccacatt cgccatcata aaagatgtta tttaatttct caataaaaaa ctaagatgaa
     5701 gacatcttag tcaataccgg cggccggggt cgaaccggca cgccctcaac gggcactgga
     5761 ttttgagtcc agcgcgtctg ccaattccgc cacgccggca agttgattta ttagtactaa
     5821 ggcggtaacc ggatttgaac cggtgatgaa ggttttgcag acctctgcct taccacttgg
     5881 ctataccgcc attatactat tatcaatcta taaaataaag aataaattat agaaactggg
     5941 gtagctggat tcgaaccaac gcatgaggga gtcaaagtcc cttgccttac cgcttggcta
     6001 taccccaaga ataaaaaggg cgaatgatgg gaatcgaacc cacgaatgcc ggagccacaa
     6061 tccggtgcgt taaccacttc gccacattcg ccatggcagg ggcagcagga attgaaccca
     6121 cactaacggt tttggagacc gctgttctac ctttaaacta tgcccctata aaatggagga
     6181 gagtggattc gaaccactga accctaagga acggatttac agtccgtcgc gtttagccac
     6241 ttcgctactc ctccatggtg gcgcgggaca gaatcgaact gccgacacac ggagcttcaa
     6301 tccgttgctc taccaactga gctaccgcgc catattttaa aattattaat tgaataacaa
     6361 gaacgacggt tccgacggga atcgaacccg cgatctcctg cgtgacaggc aggcatgtta
     6421 acccctacac cacggaacca gttcattatg gaggttaacg ggatcgaacc gctgaccctc
     6481 tgcttgtaag gcagatgctc tcccagctga gctaaacctc caacattcaa ttaaaatgac
     6541 ccgtacggga ttcgaacccg tgttaccgcc gtgaaagggc ggtgtcttaa ccgcttgacc
     6601 aacgggccag gtaaatttgc tacggagagt aagggattcg aacccttgag acagtttggc
     6661 accatctaca tgatttccaa tcatgctcct tcggcctctc ggacaactct ccagagtgaa
     6721 agaagctcaa tactctttct caaaatgaga actccggcag taggactcga acctacgaca
     6781 tcatgattaa cagtcatgcg ctactaccaa ctgagctatg ccggaataac atcagcgtgg
     6841 cgacgtccta ctctcacaag gggcaacccc tcactacaat cggcgctaag aagcttaact
     6901 tctgtgttcg gcatggttac aggtgtatcc ttctcgctat cgccaccaca ctgtggtgtt
     6961 atcttttatt gagtaaattt tgttcactca aaactggatt tgaagtcaca taagtttttt
     7021 tccgagt
//
LOCUS       DAJSMK010000104         6802 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.109, whole genome shotgun sequence.
ACCESSION   DAJSMK010000104 DAJSMK010000000
VERSION     DAJSMK010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6802
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.109"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            80..559
                     /locus_tag="ON488_002326"
     CDS             80..559
                     /locus_tag="ON488_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HCR3232470.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            778..1458
                     /locus_tag="ON488_002327"
     CDS             778..1458
                     /locus_tag="ON488_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HCR3232471.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            1466..2797
                     /locus_tag="ON488_002328"
     CDS             1466..2797
                     /locus_tag="ON488_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HCR3232472.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            2812..3774
                     /locus_tag="ON488_002329"
     CDS             2812..3774
                     /locus_tag="ON488_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HCR3232473.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            3885..4223
                     /locus_tag="ON488_002330"
     CDS             3885..4223
                     /locus_tag="ON488_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HCR3232474.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            4302..5009
                     /locus_tag="ON488_002331"
     CDS             4302..5009
                     /locus_tag="ON488_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HCR3232475.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(5112..6593)
                     /locus_tag="ON488_002332"
     CDS             complement(5112..6593)
                     /locus_tag="ON488_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232476.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         2213 a         1118 c         1440 g         2031 t
ORIGIN      
        1 ttttttgcga aaaacaaata atttttgaat acagcatccc tcgctttata ataaacgata
       61 gaataaaggg agtgaatcaa tgatgagtca aacaaaagtc gaacgttatt tagaagaaca
      121 aaagatcagc tatcaaccac ttgattttag tcatgtggta gaagaatctt tcacagaaga
      181 actacaaaaa agagggattg atccagcttt gatatgtaaa actctcgtag tgaaaggaaa
      241 caaaactggg gtgatcatcg cattgattcc tttgaacgat cacttagatt acaaaaaaac
      301 gagacaagtg acgaaagatc gtaaagttgg ttttcctgga atggattttg tattaatgca
      361 tacaggatat ccccacggag caaacacccc tattggaata aaactcgcac atcctgatta
      421 ttgtttttta gcagacagtt ctttaaaaga aaaagaagaa gtaattgtgt caagcggtga
      481 aatcgggaga agccttcgga taaaagtagc cgatttagaa aagatcgtcc atcctattta
      541 cgctgattta attagttaag ggacgagaag agaagctaag cagagcagag acctcaaact
      601 tgagattata tctgcttggt acttggtgca tcctgtatta tctgttacaa ttgctttgta
      661 catactgtac tatcaatcca atgaaaatat atttagcagc tatatttttt cattgatgtg
      721 caagtgatga aatcgttttt aataaaaaag atacagagaa aacgcgaggt gtaaaatatg
      781 aaaattacgt atcatggaca ttcctgttta acaattgaaa tggaaaatgg ccaacgcgtg
      841 atgattgacc cgtttattac aggaaatcca ttgacagact taactgcaga agaagtaaag
      901 acagattggt tgctgattac tcatggtcat agtgaccaca taggagatat gattcctatt
      961 gcaaaagaaa atcaagccac aattatcagt attgttgaga ttgctgatta tgcgaacagc
     1021 agaggagtag attcattcgg tatgaatatc ggtggaaaac atgcgtttcc attcggcgtg
     1081 gtaaaattcg tacatgcaca gcatagttca agctatgaag tagacggtat cgttcagtat
     1141 atgggcgagc ctagcggaat tattattcaa gcagaaggaa aaacgattta tcatgcaggg
     1201 gatactgctt atttcagtga tctaggattg cttgcagaag aattcgatat tgatgtcgct
     1261 ttcttgccga ttggcgataa ctatacgatg gggccagaag atgcagcaaa ggctgcgcaa
     1321 acaattcgtg ccaagaaagt agttccaatc cattacaata ctttccctgt cattgaacaa
     1381 gatcccgaat cttttgtaga gttactggaa gatagtgaag gaaaaataat gagcgtctcg
     1441 gaaacgctgg aagtgtaggc agaaaatggc gacaaaacat gatttgattt tagaatatat
     1501 tgaaagttta cctgttggca atcgaatttc tgtaagaagc atcgcaaaag aattgaatgt
     1561 cagtgaagga acagcgtacc gtgcaatcaa agatgcagaa aatgtcggac tagtttcaac
     1621 aattcaacga gtagggacca tccgtatcga acgcaaatta aaaaaacata ttgaacgttt
     1681 gacatttggc gaggtcgtca ggatcattga aggggacgtt ttaggcgggg cggcaggatt
     1741 agacaaggtc ttgaataaat tcgtcatcgg cgcgatgact aaacatgcca tggaacgcta
     1801 tattacgcca ggatcactaa tgatcgtcgg caaccgggcg gaagtccaaa aattagcatt
     1861 ggaagatggc gccgcagtat tgatcacagg aggattcaat acgactgctg agattgcaaa
     1921 gctagctgat gatcttgaaa tgccgatctt acgcacctct tatgatacat ttacagtcgc
     1981 aaccatgatc aaccgagcgt taagcgacca attgatcaaa aaagatatca tgcttgtcag
     2041 tgatatctat atgccagctg aaaagactca ttatttgcag cagacagata cgatttctga
     2101 ttatcagcgt ttgtcagaag aaacgcagca ttcgcgtttt ccagtcgtca accgccatca
     2161 tcgtttgatg gggattgtta cggcaaaaga tgttttaggg aaatcgccaa accagatcat
     2221 cgatcgggtg atgacgaaag aaccaatcag tgtaaagaaa acaatgagta ttgcctctgt
     2281 tagccatcaa atgatctggg atgggctaga agtcatgccg gtcgtttccg atgacttgac
     2341 attggaaggc ttgattaccc ggcaagatgt aatgaaagcg atgcagcttg tccagcgaca
     2401 accgcagatt gcagatacga tttcggatca gatatctgga aatatccata cgattgatac
     2461 tgaccgtgaa ggaaatcgtt tggaaaaccc taagttcaaa ttcgtagtag caccacaaat
     2521 ggtcaatggc gttggaacca tttcttttgg cgtacttagc gaaatcattt ctgatgtcgc
     2581 acaaaaaaca atggtgatga accaaaaacg aaatatcttg attgaacaag tgaacctaca
     2641 ttatttgcgg ctgatccaat tggaaagcga attagacatt cgtccacgtg tattggaaat
     2701 cggcagacgt tccgctaaac tggatatcga agtgtttatt gaaaacacca tcgtttccaa
     2761 agcaatcgtt gtttgtcaag taatggaacg ttcttagaaa gcaggagtga aatgacagta
     2821 cagcaagaaa tagtagatac aataaaaaaa tacgataaaa tcattatcca caggcatttg
     2881 cgccctgatc ctgatgcatt aggatcacaa gtaggattag ccgaactatt acgggaaagt
     2941 ttcccagaaa aagaaatacg tcaagtaggt gaaacgattg aagggcttcg ctttttagca
     3001 gaaatgcaag aagttgaaga tgtcttctac caaggagcgc tagtcatcgt gactgataca
     3061 gctaattcac ccagaatcag tgatcaaaga tatcagttgg cagaaaaact gatcaaaatc
     3121 gaccatcatc ccaatgatga cccttatgga gatcttgtgt gggtaaatac aaaagcaagt
     3181 agctgtagtg agatgattgc agaatttgct ttgatgtttc ctgaatcttt aaagatgaac
     3241 gttaaggctg cacggttact ttatgcagga atcgtcggag atacagggcg ctttttgtat
     3301 ccctccacga cgtcccgtac attagagatt gcttcgatat tgagaaatta tccatttgat
     3361 gcaagtgctt tgaacagaga gattgaacaa atgccgatga aagtcgctaa actttccggt
     3421 tatctttatc aaaatatcca ggtggatgaa aatggtgcag gaagaataat ccttccgcaa
     3481 gaaattcttg ataaatatgg aatcgatgat tcagagacag cttcgatcgt ttcacttcct
     3541 ggagtgattg acgaagtgct ggcttggggg atttttgttc agcagccttc agggtattac
     3601 cgcgtacgtt tacgttctaa ggggccgatc atcaatgaat tggctaaacg ccatcatgga
     3661 ggaggccatc cattagcaag tggtgcgaat gcaaaagatt tagcagaagt agaggaaatc
     3721 tataaagaga tccaagatat atgccaatcg tataagagca gaaaaacaga atgatacttc
     3781 gttcgaaaac gtgccttttg tagtaaaaat cacaaatgta tcttttcaag atcttctttt
     3841 tccgttacaa tagtgctcac taaagatttt aaaggagaaa gaagatgaca ttaccaaatt
     3901 gcccagaatg tggctcagag tacacatatg aagatcgagg cttgttgatt tgcccagaat
     3961 gcgggaacga atggaacaaa gaagaacaag aaactgtcat agaagacgga ttagtggtat
     4021 tagatgcaaa tggaaaccgt ctgttagagg gcgatagcgt gacagtgatt aaagacttga
     4081 aagtaaaagg tgcgtcaggt gccattaaac aaggaacaaa agtcaagaac atccgtttag
     4141 tagaaggcga tcataatatc gattgcaagg tagaaggatt tggaccgatg aaactgaaat
     4201 cggaatttgt gaaaaagaat taaagaatat tcaaggtctt ttcacattct tttcctacta
     4261 ctaatgataa aataaagtaa acgaaaagga gtgaaacgaa aatgtatggt tatggaatgt
     4321 atggtttttt agatccgaca tttcttttgg tcattcttgg attagttatt tccggaattg
     4381 cgtcagcgta cgtcaatagt actttccgaa aatacgatca agtgagaagc aaaaacaatg
     4441 tgactggtac acaagcagca caatatatat tacaaagtca acagataaat aatgtcggtg
     4501 ttcaacaaat tgccggagat ctcacagata actacaattc aggtaataag atgttgagtt
     4561 tgtctcaagc aactgcacag tctacttcag ttgctgcgat aggtgtagca gctcatgaat
     4621 gcggacatgc ggtacaagat gcttcgggtt atgtcccatt gaagattcgt gcagcacttg
     4681 ttccagcagc taactttggt tcgatgattt cgttcccctt gattatggta ggtgtattgc
     4741 ttagctggaa ctctacgtta atcaatatcg ggattttcgc tttttcttta gcattacttt
     4801 tccaattggt gacattacca gtcgaattta acgcgtctcg gcgagcaatc caaattttga
     4861 gtgaaggcgg actactgacg gaagaagaag taccgatggc aagacacgta ttatttgcag
     4921 cagcactgac ttatgttgca gcagcgcttt cgacattcct gcagctgttg cgcttgatct
     4981 tattgttcgg cggcaaccga agagattaaa ataaagaagt tgtgaaatca gcgctttgat
     5041 ctgagctaat accgagagtt agctgattga ataccattta tttggaataa gaggatgtga
     5101 caagaatttt gtcacatcct ctttgttttg ttctcataac cttttttcat atacagttca
     5161 tgaaccgctt ttattaactt gccaaataac actgtattgt gcgttgtatc cagatagaaa
     5221 gtctccgttt catctgaaat tttctcatgc tgatctgtaa tgatcaaatc agcatgttct
     5281 gaatatgcgg taattttaac agcatctttg cgaaataact gctgcaaatg gctttgaaga
     5341 tgataatttc ctgtaaactg tttggttatc tgcaaatgga tgagtaactg ctctttcgtt
     5401 tctgtttgta gtaagtgttg gatcaattga ctaaggtatt gactgatttg gtttctttcc
     5461 ccattttttg aaaaaattgt atcgattttt tctcttaatt tcttttcctg tataaaagaa
     5521 ctagaatgat tggacgtggc ttctggaaag caaagtgtag aaaaactact gctggattca
     5581 cccaacagtt cgaaaaaaac aactgccaac acaagaaaat aaaaataaat tggtatttta
     5641 ttttctaaat ggttgagagg aaactgttga gttaagtaag tcatcaattg accgacttgt
     5701 cgacaaataa ggtttttgct tgtggaaaat aaaaaaccaa tctcctgttt ttgtcgaaaa
     5761 gagatttgat ttggaaaaaa acaatagaaa aaataattaa agtaggctct ctctgtttct
     5821 gtctcttcac aagggcgact cactgaaaaa gaagtaaagt attctgaata atcatgtgta
     5881 tgctgcaata agtccatcaa ttcagtgatt tcagaagaag tttttggaaa atatgcctgt
     5941 tgtttgtttc gtaatatgaa taaagttaac agcaagtaga tatttttttc ttgttttgaa
     6001 attttttcta tttgctcatc tgtactgttc atttttagtg catttaattc aagtgaggaa
     6061 aatggccaat cgttacctcc aaatgtatct gaaagaaaaa agtaaagata gagacggata
     6121 gataactcat ttccttcaag agtacagcaa ttttttacag ataggatccg taaatggaat
     6181 ttttttaagg aatgattgag ctgttttgtc agtttttcga gataggaggg cgatatataa
     6241 agttgttcaa gtaaatattt ttttggtaca gcagtttgtg gataattgat tagtaacatc
     6301 aaatagttaa aacgattgga ttcttttagg tagcataatt ttaacttaga aaaaacagct
     6361 aactttttag tttgatcggt ttctttggtt tggatctctc ctttatgatt agaataaata
     6421 aattcatcaa tcaataaaaa ttgcttgagt gatacattta tttttcggat cagttctttg
     6481 attgtccgtt ttggaatatg taagtcattg gataattctt gtaaagaaca attatttttt
     6541 tgaatgacca tttgtagaac aagtaactct ttttttcttg cttcaattag cataaatacc
     6601 tcctttttat tctgtttttg tatatagtta gacaaaaact gtgagtggaa agtcatttca
     6661 gtctgtgtta ttctcacaga gtgtcgcctt cttttttata taacgttatt taattttttt
     6721 gttaccttgt ttattctatt gtttatttcc tagggtattt tgtcaagata ttcttgtttt
     6781 taaggcggaa aaattgattt tt
//
LOCUS       DAJSMK010000105         6592 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.110, whole genome shotgun sequence.
ACCESSION   DAJSMK010000105 DAJSMK010000000
VERSION     DAJSMK010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6592)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6592)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6592
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.110"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(168..566)
                     /locus_tag="ON488_002333"
     CDS             complement(168..566)
                     /locus_tag="ON488_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HCR3232477.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(563..799)
                     /locus_tag="ON488_002334"
     CDS             complement(563..799)
                     /locus_tag="ON488_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCR3232478.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            complement(959..1243)
                     /locus_tag="ON488_002335"
     CDS             complement(959..1243)
                     /locus_tag="ON488_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232479.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            complement(1414..3642)
                     /gene="topB"
                     /locus_tag="ON488_002336"
     CDS             complement(1414..3642)
                     /gene="topB"
                     /locus_tag="ON488_002336"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HCR3232480.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            complement(3816..4226)
                     /locus_tag="ON488_002337"
     CDS             complement(3816..4226)
                     /locus_tag="ON488_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HCR3232481.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            complement(4343..5506)
                     /locus_tag="ON488_002338"
     CDS             complement(4343..5506)
                     /locus_tag="ON488_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCR3232482.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            complement(5684..6538)
                     /gene="aroE"
                     /locus_tag="ON488_002339"
     CDS             complement(5684..6538)
                     /gene="aroE"
                     /locus_tag="ON488_002339"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HCR3232483.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
BASE COUNT         1767 a         1386 c         1074 g         2365 t
ORIGIN      
        1 ttcctactat tcactctttt gtattccttt taaatcaatt atttcaaaat taatccatat
       61 tttccatatt tttatgaaaa aactattttg tatgattaaa cataaaaaaa tcagcatatt
      121 ccttaatgac atgctgatct aattgagaaa taaagttttt aattcgttca ttttattgcg
      181 gtttgtcgta aataactggt tatcttggac tttagtgaat cgaaatccaa tgaactagtg
      241 gtaatcatta tgataaaatc aacagcttct tgacgagaaa aagcaactgg acaattattc
      301 aattgaagaa acaacaacat ggcaacaaga gcagttcgtt tattgccatt atgaaaagga
      361 tgttttttag ctaaattaat tgctaaaatc gccgcttttt catagatttc aggatagagt
      421 tcttgattga atactgcttg tgaaggctgt ttgacggcca tatctaatgc atttgcatct
      481 tttacaccga tcatttcgcc tggcgagtga cgtaaaataa ctttcgcgtt gattttgata
      541 atttctttag tcgaaagata cctcataaat caaccaaatc ttttaacgcg tcttcatatt
      601 gattcatgat cgaatcaact aatgaatcaa tatcaggttc ttcttgtgct ttgatcattc
      661 gtacagaacc atcagattga aaaacataac tgattgcgtc acctgtctgc acacccatga
      721 attcttttac ttctggtggg atagttgtta catcgctatt gccagatttt ctaattttat
      781 actttttcat ttttttcata tttcgccacc ctctatacca ttctcattct atagtaagta
      841 cattatatcc aagtatatac ttttaatcaa tgtatatact tttattttgc tttttcttac
      901 gaaaaaatga caaagaaaaa agtttgtgac atgacttttg tcacaaactc tcgtattctt
      961 aaccaaaata ttgatgaaat acttgtgtaa taactggtag aaaataaata atgatcatag
     1021 ccgctaccac caccaacaat tgttttcgct gtttctttcg ctttagcatg cttgtcgttt
     1081 tatgaaaaaa ataagtagcg cttttagctc ctgcagtcaa agtcgataaa atcaacgttg
     1141 gtgaatatgc tgtttgattg tgcgtcaatg acaacaactt cgtcccgtaa tcaggatact
     1201 ttagaaatgc ttggtacaca gccacaatcg tgattgctcc cataagataa tttaaaaatg
     1261 aatgcacttt tttcaaataa aaaaactcct tgctatctat ataaaatcag cctaccccaa
     1321 cgtttttgct tgattcactg atatttttta gttttattgg tatttatatt ctcacttttc
     1381 ggaataaata ttccgctatt tcattgtttt catttactct acttcgtttt cattattttt
     1441 tcttgatgtt tctttgtttc catcaactgc ttttgttcca ctgttttcga tccatggaaa
     1501 agaaaaaccg attgtcatat cttcttttaa tactaaaact gcatcgaatt tccctttttt
     1561 accagtaaaa cctttgacaa ctttacttgt ctttcctttt gaaagcaaat ctctgagatt
     1621 cgttttagtc agcttctttt tagctactgt tggccacaat ttgaagtcgc attccggatt
     1681 caagcatgta gcgattttag gataaagcat gactattccc tttttacatt ttggacatct
     1741 tcctaattga tcgtttttct tctccatcgc ttttatctga cgtgtcccgc taatctcatc
     1801 tgaaaagtct accttgtcga tttgattagg aacttctgcc aataaatgta ggatgaattt
     1861 tttgatattc tctaaaaaaa cagatggtgt cccctcttgt ttaccaattt ttctcaagta
     1921 cccttcccag cgcgcagtca tttctgcgct cgtcagtaat ggttcattgg ctactgcctt
     1981 acaaagagtg attccttttg gcgtaacagt tatttcgttt ttattgactt cgatgtaatg
     2041 cttctgctta agattttcaa tgatattggc tcgtgtagct tctgtcccta ttccttctac
     2101 ttctttgaga atttcttgcg cttcatcatt atccagcgtt tttcccgcag ttttcattgc
     2161 tgtgatcaac gttccttcgg tatagggttt tggaggttgt gtttctttct ccatactttt
     2221 cagttctact tctgcttctt cattttctac gataggagga agagtctgag cttctttctt
     2281 ttttgacttg atgcgtaaga tttcctgcca accttgctgt aatgggatct ttccgatgct
     2341 ttttagcttt aattgctgta cgcccgtcat tacggtcgtc tcttcgtaga tataatctgc
     2401 agcaaacata gccacagtag tgcgcaaaac ttgcaaatag attgcttgct gtaatttgga
     2461 aagcttcgca aagcgtgcag gagtcggaat cgtctttgtc ggaataattg catgatgttc
     2521 ttgaactttt ttcgcatcga catatcgttt ctttgctttg atctcagttg tctgtacttc
     2581 ttctattcct aaaaattttt tataattttg cagatgttta accagatact gatgctcatt
     2641 ttctgtaatg taaaaggaat ccgttcttgg atagcttaga aacttgcttt cgtacaatcc
     2701 ttgagcagca tcaagtgtag ctttggcact tgctttcatt agctgattca tctttgtctg
     2761 caaactagat agcgaaaata aacgtggact atgcaacctc ttttcctttt tcgtaacttc
     2821 aagaatccgt ccgttttgct tacctaaatg cgctccaagt ttttctattt ccttcgttaa
     2881 ctcttcttgg gttttaaatg ctttttttgg tacgattttt ccagaaaact gccctttgtt
     2941 tgtcgtaatt aaaccttctc cttcaaagta cgtttctttt ttgaagtgtt tgatttcttc
     3001 ttgcagctga taaatcatat agagtgtcgg tgtttgtaca cgaccaagag aaaaactgcc
     3061 atcaatccct tttcgttgaa gtagcaagct atataatgga cttccattca ttccaatcag
     3121 ccaatcagcg ttctgccttg cttgcgcttc tttatatttt ggaaaatagt tctttccagg
     3181 ttggagattc ttaaaacctt catagattgc ttctttttca agagaattga tccataaacg
     3241 taaatagttc ttttccttag aaaatgcgtt tgcttgtcga ataatcgacc acgcgatggc
     3301 ttcaccttct cgatcaccat ctgttgcaat aatgatggta tcggctgact gcaattctcg
     3361 ttttacgatc gaaaattgtg cacgtttgtc cattggaact tcgtaacgga aggtttctgg
     3421 gaaaataggc aaattttcta aagaccattt tgcccaacgc tcttcataag ctcctggagc
     3481 aaccatatct accaaatgtc caaaaccata agtgatggtt acttcaccag caaacaatgg
     3541 atcgctgatt tcataatacc cttcatgccg cttttgctgt tggaaggttt cggcataggc
     3601 ttttgcttgt gaaggttttt cagctagtat caccgtcttc atcttctgac ctccgttact
     3661 taattttttg cggacttctc tattatggaa catattttcg catctggcaa taaaaaaaag
     3721 ataccgtata gtcgaaatag acacaaaaac atcaagcaaa caaacgatga tccgtttgct
     3781 gcttgatgtt tccagaaaat attcatcttt agctgtcact cttggttaat ctgccagttg
     3841 atgccaaatc gatcagttac catcccatac aactgagccc acggaacagc atccagtggc
     3901 atctcaatct taccaccctc agctaagctt tcaaataggc gcttcgtttc ttcttcattt
     3961 cttgtctgga tgactaaaga aacattattt cccacaacta attcaggacc aattccttct
     4021 ggcgtatctg caaacataac taatgtatca taaatgttca gccgtgcatt cgtgattaga
     4081 ttttttgctt cttctggcaa gttcatttgt tctattccag gcatttcacc gtatgtggtg
     4141 atacctgatg cttcagtctg aaaaactttt tcataaaaag cgatggcttc acgcgactca
     4201 tttttgaagt tcagatagat atccaatgta aacagctcct ctcttggtta aatctaccat
     4261 aagaaagcgt tttttacgag tgaatcgttt gattgattca tgacaaaagc cttgcgcagc
     4321 ttcttcttga tcttttttat gatcatttat tcaaaaaatc tgtaatagca gattgattca
     4381 tttgattatc aatttcaaga atactgccag cataatcact ttgcccataa ttccacgaac
     4441 cgtctactgg cacacttatt cgatcaatgc caccagctcc tcgtgcaatc gaaaagaggt
     4501 ttttcgtcaa gaaccaagca gtgacatctg tggatgtata tcctaaagct ttaccagctg
     4561 cataaggtgc acggatcaga ttcaatggat tcttcaattg gctgaaaata gcgttcatta
     4621 cttgctgttg gcgtctgaca cggccaaagt ctccttgttc atccattcgg aaacgtgcgt
     4681 actgcaaaag aacatgtcca tccatcttct ggcccccttt tttaatatct acaccatcca
     4741 gattcagatc tttttctgca tcgatcttca ctccgttcat gaataaggca tcgatcactt
     4801 tttcaaacga tttgaaatcg actttcgcat agtattgaca atcgattcca aaattttcta
     4861 ctaaagtttg acgcactaga tcggctcctc cgtatgcata agctgaattg atcttatttt
     4921 gtcctacccc tgggatcgta acgaagctgt cacgcataaa agaaatcagt ttcggcttat
     4981 gggaaggacc atccaactgt aagaccatga tcgtatcggc tcgcccggca tcttctccgc
     5041 gtgtatcact tccaaggatc aaaatattat gcgcaccatt cgtcgctttt tgcccatgaa
     5101 aggtttctga agtcgctgcc tctaagcttg tgtcatgttc agctacatat ttaccaataa
     5161 aaaatgagat acctgaataa aggatcaaaa caagcaaaat cgatagaatg atttttttcc
     5221 acgatcgctt tcttcgaggt tttaacggtt tgttcttctt ttgccgattg aaaaattttt
     5281 tatttttttg ttgttcttct gctcttggtg catctctgta tatctgttgc tcgtattggt
     5341 tcaaatgttc aaatgaatgc tgctctcttt cataaatacg ggtagcatct tcctcatttt
     5401 ccatacgcgt tcgttttcgt tctcttctag caaaaatact ccccgtatcc cgcttcagag
     5461 gtttcgcctt cttatggatg tccttatagc gatccatccg actcattgtg gttcctcctc
     5521 gtttcttact gataaataaa ggatacgata accaatcgac aaaagcctat cattttttga
     5581 taatttaata aaaaataacg aaataaatgc ttcgatacat aaaggattac ttttcttgag
     5641 accgtttatg cgagaataaa agatctttat ctattatcct tttttaatca aacagctttt
     5701 caatcacatg gatcggcatc ttttcctttg tccataattc aaacgcgatt gctccttggt
     5761 agatcaacat gccaagtcca ttgtatcctt ttgctcctac tttttttgct tcttttaata
     5821 aacgtgtttc tctaggtgca taaatcaaat caaaaaccgc tagattctca tgcatcatgc
     5881 ttatatctaa gagcggtgac tgattgattt tctttcccat cccgatatct gttgcattga
     5941 ctagaagaca gctttctttc aagtcttttc ttaattgatg cgtatcggca aagtcacgaa
     6001 cttttatctt acaagaagtt cgatagctga gttgttcgaa tgtttctttt acttgagcga
     6061 atgtttggtt gtttcgttta taaactacga tttcctcagc gccgtctaac gctgcttgaa
     6121 cagtgactgc ctttgctgca cctccagctc ccagtagagt catttttttc tttttgatcg
     6181 aaatcccagc ttcttgcacg gattgcatga agcccgcacc atcagtatta tagccaatca
     6241 aacgaccctt ttcgtgcacg atcgtattca ctgctccgat caattgcgct tcctggctta
     6301 cctcatccag ataaggaata accgctgttt tattcggcat cgaaagattt acacctaaca
     6361 tatcaaaagt tcgaatactt tcgactgctt gcttcaaatt cattggattt acttggaaag
     6421 ctaaatacac cgcatcgatg ttgtttgctt caaaagcagt attgtgcatc aatggggata
     6481 aactgtgaga agccggatca gcaaagagcc cagctaattt ggtttgtcca gaaatcatct
     6541 tattcctcct ttgttcttac ttcaataaaa aaagccactt agcgtttgat ac
//
LOCUS       DAJSMK010000106         6467 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.112, whole genome shotgun sequence.
ACCESSION   DAJSMK010000106 DAJSMK010000000
VERSION     DAJSMK010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.112"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(110..565)
                     /locus_tag="ON488_002340"
     CDS             complement(110..565)
                     /locus_tag="ON488_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232484.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(719..1927)
                     /locus_tag="ON488_002341"
     CDS             complement(719..1927)
                     /locus_tag="ON488_002341"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HCR3232485.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2039..2371)
                     /locus_tag="ON488_002342"
     CDS             complement(2039..2371)
                     /locus_tag="ON488_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HCR3232486.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2519..3394
                     /locus_tag="ON488_002343"
     CDS             2519..3394
                     /locus_tag="ON488_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HCR3232487.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3476..4057)
                     /locus_tag="ON488_002344"
     CDS             complement(3476..4057)
                     /locus_tag="ON488_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HCR3232488.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4063..5322)
                     /locus_tag="ON488_002345"
     CDS             complement(4063..5322)
                     /locus_tag="ON488_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HCR3232489.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5324..6370)
                     /locus_tag="ON488_002346"
     CDS             complement(5324..6370)
                     /locus_tag="ON488_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232490.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1804 a         1337 c         1102 g         2224 t
ORIGIN      
        1 aaaatcttgt cacagtccct tattctgaat aaacggtgtg gaagagacag cctatcagta
       61 gtaataagac acatctcttt cacagcctca tttttgcgta aaaatcgatt tattcgaaaa
      121 attccccgta tacatcttct acacgttgat ctggattgat cacgatatac aagttacctg
      181 ttttttcgct gatttttgtt gattgatatt gattgtctaa tccttctgtt cctttatcta
      241 gatatgggaa gtacacaaga tcaggtgtgc catttcggta aaggatttcc attcgctcga
      301 tatcttcgta tttcaatgcg cgattaaaca tgcccatttc cagtccgcct aggttgatat
      361 catgtgtcgc aactgcgtcc ccttcatgga agatttcgat tttaaatcca gcacacggat
      421 ggatttcaac aaattcactg ccattgattc gtccaaaact tgttgtgatt tgtttgatcc
      481 aaagatcgcc gatatgacgg cggttgatcg tccaggtttc tccatttcta aaataaaatt
      541 ttagcgctgt catttcttta ctcattaaaa agactccttt atgatgtaat ttattcttgt
      601 actacctcag tttagcacaa atttatgtaa gtggtcacat cttatgtttt ttcttctaat
      661 gacgtatctg cccactttaa gtagccaaca aagctgagca gatacagtct agtgtttttt
      721 aaatcaattt ttctttcgat aaaaaatcca aaacctgttt tttatcattt tttattcttt
      781 gttctacgac ggctttttca gctaattgca aagcttcact aacccactta ccaggttttt
      841 ttccagtttc ttctagcaag attttaccat ctactgctaa ttcgcttaat gacttgatag
      901 gtaaacgatc ataggattct cctacggcat ccatctgagg tgtttcgtca aaatagatca
      961 tcaattcttc tacttgcagt gcatgttttt tgcctaagaa gtacaattcg aatggttcca
     1021 aagctccagt ttctcgttgt cgtagtcctt ggacaagtgc ttgaacgtct ttaatcattt
     1081 ggttagaaca cttccacgat ttcaaaaagg aacgaatctc attttctttt agatccagtt
     1141 ggctgatcaa taatgcccat gcttggctct cttctttcaa tgggacggat ggtaattcag
     1201 caaaacgtaa aagtgcttcg ccttcttctt tcaaaccggg acagcaaatg tagcactctg
     1261 tttcaataaa tgcatggatt cccgcggccc gttcatttcc caagagcatc ttgatgaatt
     1321 ccacatttat acgttctaca gatattttac ctaatagctc gtggttttct ttgatggcgt
     1381 agaaggtttc ttcctctaat ttgaacccta gttgactgac aaaacgcaac ccgcgcatca
     1441 ttcgtaaggc atcttcatgg aaccgctcat gaggattgcc tacagctcgc aagatctgtt
     1501 cttctagatc ttgcagacca tcgaacaaat cgatgatttc tccatcttct ttcaaagcaa
     1561 acgcattgat cgtaaaatct cttcttttca aatcttctgc caacgaacga acgaattcga
     1621 catgatctgg tctacggtag tcctgataag ttgattccgt ccgaaatgtg gtgatctcat
     1681 attgttcatc attttctaat accaacacag ttccatgttc gatcccaata tctatcgttt
     1741 ttggaaaaag ctgtttgatt tcttctggaa atgcgcttgt tgcgatatcc acatcatgga
     1801 ttggctggtt cagcaagata tcacgaacac ttccacctac aaaataagct tcatatcctg
     1861 cattctctaa ttttttcaga actggaattg ccttttggta ttccagaggt aattgtttta
     1921 atttcatttt tccaaccttt cctgcgtgtt tcttgtcctg agataaagac tcagttgcat
     1981 ggtgactgtt tgacaagtcc gtttcagagt cttcaaggcc aggaccactt catcttgttt
     2041 actcgtcctt acgctcaaag cgattatggt ctctttgatt gaatttttcc atgttttttt
     2101 caaaaacttc agttaagtcg atattcaatg aattagccat gatcatcgta acgaataaaa
     2161 catcaccaag ttcttctgct accgagttaa ctggttcaga agcctttttg cttttttctc
     2221 cataagtgtg gttgacttct cttgccaatt cacctacttc ttcagttaat cgagccatct
     2281 gagctaatgg agagaaatac cccaccttga attgctggat atattcatcc acttcctgct
     2341 gcatactgta taaagaacgc tttttatcca tctttttccc tccaaaacta tcttaccaaa
     2401 actttaacgc aaatcctaga taagagcaat tgagaaaatc gaatttccat gctacattta
     2461 ggaaggaatt tctaaatgga aattctgtga aaatacataa ttgaaagctg gaattcatat
     2521 ggtcaaacga aaaacagtaa aagaagttct ttttatcatt ataggaacaa gtatttatgc
     2581 atttggtctt gtttacttga acatcgctaa tcatttagca gaagggggag tctcagggat
     2641 caccttgatc ttaagagctt tatttggtat tgatccagct tatacgactt tattaatcaa
     2701 catcccattg attttactag gaggaaagat cctcggtaaa cgttccttgg cctatactgt
     2761 tctaggtaca ctttctttgt cattcttttt atggatctgg caaagggttc cactagaaat
     2821 caatttacag catgatctac tgatcgtttc tctacttgcg ggtttagttg caggtgtagg
     2881 aagcgggatc gtctaccgca tgggtggaac aacaggcggc agtgatatta tcgctcggat
     2941 tttagaacaa aattacggca tcactatggg gcgttcccta ttggcatttg atatcatcgt
     3001 cttacttgct tcattaacct atatcgactt gaaacgtatg atgtatacgt tgattgtttc
     3061 gtatgttttc agtcgtgtga ttgattcgat cttagatggc ggatattctg caaaaggtct
     3121 acttgtcgtc tccaacaaaa gcgaagagat tgcaccacta ctgatgaccg gtctgcaaag
     3181 aggtgtgact ttcctttctg gagaaggcgc attctctggt aattcaaaaa aaatcatcta
     3241 tatggtcgtt agctctagtg aattaactga agctaagagg atcgtccacg agattgacga
     3301 aaaagctttc ctttcaatca tcaatgtgca tgaagtggaa gggcaaggct ttacttattt
     3361 gaagccacag acaagattac tgaaaaaact ataagaaaaa agacaaagat aggctatgag
     3421 gaaagattcc acatccagct gacctttgtc ttttttagta ctatactatt tttaactaat
     3481 tgttatgttc acttacccgg ttacttttct tttgtgtctg caaaaggatc tttcggttaa
     3541 cttcatcaga taatttcaaa aaagcatccc tatctccatc ttctagtgct tgatcgattt
     3601 gagcataaag catttttagt tttgcctctt cttctttttc ttgaaaatat cgttcaatta
     3661 attcagtatc ttcttcactg actgaagaat cccaagaaga aaatggattg tcttctaaga
     3721 tagatagata ttctcttgtc tgccaagcat tttcgaatat acattccaca tataaaggct
     3781 ttttccaatt caaacggatt tcatgaaaaa tctggtctgt gtccgtaaat tcttttccct
     3841 gcaaaaacaa tttcatgggt tccccttcaa cagatagatc actgatctgc agtcctcgat
     3901 ccgcaaaatt cgccccttca acaaagtgga cattgcttaa aatcgcttca tgattggcaa
     3961 gataattcaa gatccaaaaa acttctcttc ggctaaaaga tacatgattg accatccacg
     4021 ttaaaaaatt cttcttttcc cgtacatcaa ttagcatttt tctcacctct ctgttaggtc
     4081 atctaataat gacagtgcct ccatatctcc tggttcaagt gttaaataat aagtcaataa
     4141 ttcttgcgct cttttcagct gcccttcttc tcttaagaaa aaggcatact ctttcaagaa
     4201 atctggttca tgtgatagtt catgataagc ctgttcatag tgtacagctg caacggtaaa
     4261 gtcttctaat tcattataag catgggctag gttccattct gcataaggat tagcagtttc
     4321 ttccatctga ttgatcactt gtatcacatc ttcatatctt tcatcatcca agtaaagatt
     4381 acttaaagta agtaatgttt catcttgttt gtctcctact tctaaagctt tcagtaaaag
     4441 ttcttctgct cgctgtctat catgcagacg gaaagcattt tccgaggcca ggtgataaag
     4501 ttcgacttgg taaggatttt ctttgattcc ttcttctaac actgtttgtg cttcttcaat
     4561 catttcttct tcttgaagag cttgtcctag atatagatat aacgattgat aatgcggatt
     4621 aacttctcga agttcttcca gatagttgat tgcctgctga ttttctttca attgaagatt
     4681 cgtaaaagct agctggaaca gtcgatcatc tgtcctttct tctttcagtg cttcttctaa
     4741 aggtacgata gctgcttcga attctccttg catacttaag gattgtccta aacgttcctg
     4801 catcgagatt cctgaaattt catttatccc gcttgccaac aatgtttcat aaaccactgc
     4861 tgcctctttg aaacgatcaa ctgaaaaata caattcagct agcgcaaact ggatcaatgg
     4921 ttcatcagga agcaacccag ctgcttcttt caattttgct tcactcactt cagggattcc
     4981 gataacttgg tacaaatcag ctatcgccaa taagctttgc ggatagtaat cactttgctt
     5041 atccactttt tccaggtatt caaaagctaa gtcgatctca ttatcttcga ttgcaatttc
     5101 tgctaacggg atgttcagtc cgtcattttc tgggtattgg ttgatcagtt gttcaaaaat
     5161 ctgttttgct tcgatcaaaa agccaatagc cagcaattct tcgcctagtt cagctaatat
     5221 atctgctggg tcttctttta atgctttttc taaaaagatt tgtgcttgtg acaagtcttc
     5281 atctgataaa gcttgcaaca ttttttcgct atttgtattc atttcaattc cctcttatct
     5341 cactgacgat ttgttgaaat accgtcattg ttctcaataa ttctttttcg tttggatgtt
     5401 ggtatccgtc tattatacct attttttcta aaacaagtat ttttttgctt ttttctgcca
     5461 aaaaaagaac tttttccaaa tactccatct ttgaaatctg ttccagccag tggattggat
     5521 agccaagcaa gtccagccac acaaaaaagt tttttagttg gaaatcaaaa ggatatgctt
     5581 ggagattcca cacgaaatga aacatcattc ctaaaaattt tttcatacta gcagaaagta
     5641 gatggccatt ttcggtcaga taaaaagctt gttcaaacag tttaccataa tttgacaggt
     5701 tttctgcctc taattgataa aaatagatca tttcttcgat catcccggca aacggccgag
     5761 tcgttaattg ctttttattt ggatagtttt tatacagatt ttgcaaaaaa cgatgatcac
     5821 aaatcattcc gcaacagata aaagtcaaaa agtcaatctg ctttccgtcc acctgccgct
     5881 cgctgattgt ttgatcataa acgatgcgtt ctggcagatt gatggtttgc agcactacac
     5941 gatttggtag ctgcaaaatc gtccgctgcg gtgttaatgc tcggcttaga gaacggatcg
     6001 atacagggat catccatagt gatgaatcaa gggttgtatg tttttgaaaa aaacctgcca
     6061 gatccatgat cccttcattt ccaaatccga tgataaacat ggattgattt tcgggatagc
     6121 gtttgacgaa atcaagcagg ttctttaatt ctgttaaatg attgcattga gtgttggcac
     6181 aaatatacca gtcattgttt gcttgatttg caaataacgg gttgatctta tctgcaaaca
     6241 aatcataata gcgctgattc gttaaaaata agattggctg atcaatggaa agttctctta
     6301 gctgactgac tagcgtttct ccgtaaaaca ctttcgtcaa cgcatcttct acttgataat
     6361 caagttccat acgcatccct cctcttctta tttttatttt accattagta agcaaattct
     6421 agaaaagata agagcaaagc tcacctcata acttggaaat aaataaa
//
LOCUS       DAJSMK010000107         6411 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.113, whole genome shotgun sequence.
ACCESSION   DAJSMK010000107 DAJSMK010000000
VERSION     DAJSMK010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6411
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.113"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            76..1380
                     /locus_tag="ON488_002347"
     CDS             76..1380
                     /locus_tag="ON488_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HCR3232491.1"
                     /translation="MLNDINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLS
                     QNSLFLKTCLLYLEEDEPDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPR
                     FTEMERRLLLLNVSYRLGGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILLI
                     GFAISFLRQQVCAVTIDSKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLF
                     NLCNYGFHSYQLIAEDFQQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIH
                     LMRSAWDNYQLFMPEKFYLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVI
                     ELSGILRLTKEHLTIYIVTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQ
                     QSSNRVLCERTLYTPDAVQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1472..1837)
                     /locus_tag="ON488_002348"
     CDS             complement(1472..1837)
                     /locus_tag="ON488_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCR3232492.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1834..2199)
                     /locus_tag="ON488_002349"
     CDS             complement(1834..2199)
                     /locus_tag="ON488_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HCR3232493.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2391..2639)
                     /locus_tag="ON488_002350"
     CDS             complement(2391..2639)
                     /locus_tag="ON488_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232494.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2638..2766
                     /locus_tag="ON488_002351"
     CDS             2638..2766
                     /locus_tag="ON488_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HCR3232495.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2823..4517
                     /locus_tag="ON488_002352"
     CDS             2823..4517
                     /locus_tag="ON488_002352"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HCR3232496.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKMTNTLTQ
                     EEEHVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4521..4640
                     /locus_tag="ON488_002353"
                     /pseudo
     CDS             4521..4640
                     /locus_tag="ON488_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4617..4790
                     /locus_tag="ON488_002354"
     CDS             4617..4790
                     /locus_tag="ON488_002354"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232497.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKVV"
     gene            5168..6301
                     /locus_tag="ON488_002355"
     CDS             5168..6301
                     /locus_tag="ON488_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HCR3232498.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQNGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYE
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
BASE COUNT         2121 a         1222 c         1169 g         1899 t
ORIGIN      
        1 tgtgggcaat tctatgtaaa taaagaagtc aatctagaaa agctctccaa tctcctgcat
       61 gtttgcaaaa ccactttgct caatgatatc aataacataa aaaaagaatt tgaagaacag
      121 atcgcttata cacatcggga aaaggaccgt tacactttat atttttcaga acatatacct
      181 cgatgcaaga tcatgcagca attgtctcaa aattcgttgt ttttaaaaac ttgtctgctt
      241 tatttggaag aagatgaacc tgattatctt caattaactg aatgtgaatt catctctgtc
      301 agcaaagctt attcattaaa aaaacaagta ttagcttatt ttaatgactg cgggatcgaa
      361 atcgaccgct actcccctcg attcactgaa atggaaagac gtctgctgct tcttaatgtg
      421 tcgtatcgtt taggcggttt taattcttgg gagctacctg aatcgttttt tgaacgtgcc
      481 gatcgtttca ttgaatccgt aacggaaaat agtggcagat tttatgataa agaaaataaa
      541 gaaatcttat tgattggttt tgctatcagt ttcctacgcc agcaagtgtg tgctgtgaca
      601 atagattcaa aatttatcga agaaatcaaa aaacgtccta tttacaatta tgtcgaatca
      661 gcatgggaaa acactgattt ccaaacctat tataaaaaag aagaattcgc ctttattttg
      721 acactattca atctttgtaa ttatggtttc cattcttatc agttgattgc ggaagacttt
      781 caacagctac accaagtgtt tattgacaat actcccgaaa taaaagaact agttgctacc
      841 tttgaatctc acttcaatca agaattattc ggaaaccaac cattcgaacg tgcgctgatt
      901 catctgatgc gttcggcttg ggataactat caattattca tgccagaaaa attttatctt
      961 ctaaatgagg aacagacaaa tttatataaa gaagtccaga caattttttc cagctggtcc
     1021 agccagttac cttatgatct acggttgaat cctaattgca tgcgggcttt tgtgatcgaa
     1081 ttgagcggaa ttctccgtct gacaaaagaa catctgacta tctatatcgt cacaaattcg
     1141 gatgttcatt atctgattta tcgggaagcc ttggaagctg taactacttt cgattttcaa
     1201 gttgcaccaa caatttattc aagtatatct gatataaaga agtatgcgca gcagtcctca
     1261 aaccgggtat tatgtgaacg tacattatat acaccagatg cggtccaata tgaaaatatt
     1321 attcctattt cgatcaatac gatcgatcga gctatcattt cagctgtgca aaacaaataa
     1381 gggactgtga caaaaatcat gtcacagcct cttatttgtt gaagatgccc atttctgtaa
     1441 caatctcttg atacacatca ggctcacaac ctcacttatt ttggacatct acgggtccga
     1501 tctctttatt taaaaaataa gaaatgatgg ttcggataac taccaacgcc gctagttgga
     1561 aaatatcctg caaggtaggt ttgataatcg attcgatgat cccagctgaa acaagaattt
     1621 ccaaacttag aagtatatag cctcccaaca tctttttaat agcattgttc tcgctgactc
     1681 ggtcgctttg cacttttgta tggacaaata aatatttcaa aaaatccttg attgatagac
     1741 aaacacccca aaccaataaa cagatagcaa agatatcaag tcccagtaca agtttttcaa
     1801 aatatggaag aagaaactgc atcaactctg tcgtcatcct acctctcctc ttctttgttt
     1861 ttctttgtct tctatttcct gattcaagaa ataagaaatg actgttcgaa tgataataat
     1921 aagtgcaagc ttcaaaatat ctgtccaagt cggcttgata actgactcga tgatatcagc
     1981 aacgactagt acttccaagc ttaacaaaat ataacttgct agcagttttc ttgtatctgc
     2041 attacgagta ttacgttctg catagttttt cttgacatga gaccaatcaa aaagtttgaa
     2101 tagaacaaga acgatcccga caattaagat accgatagaa caaatattta aaatagcaat
     2161 gatccattct agaaattcaa ttaaatttga gcgaaacata tacgctacct actttctttt
     2221 aatttgttcc tattctttta ttgtaaaaga aagttacctt gttcgtctat ttaaaagttg
     2281 ttctaatgat aacggttcgc ttaaattttt ctttttcact ctcccctttt tctccctcca
     2341 tccataaatc gtggaagtat ccaaaacaac gtagcaagtt aaaataaggc ttagtccgtc
     2401 atcagctttt caaagaagca ctgtctcggt gctttttttg tacccaaatt tctaaaaata
     2461 gaaccataca cctcctcaaa tcttttcttc ttacctaccc tatttttatt tacaggaaaa
     2521 tcagacactt cttctttttt gtcaaaattt cctttttctt ctcgtcctat catttggcat
     2581 tctaataaaa acgaactatc cttggatata gaaagagaaa acaaggaggc gtttttcatg
     2641 agtaaaaaat taatcaaagt cggcatcggt ttaggtttgc ttgcccttgg cgctgcatat
     2701 ctaggaaaaa agacaggact attcgaagat gacagtcatt tatatgatga attcgaatca
     2761 atctagcatc ctatttagtt gaatcactac ggacatactt ggaagacatt ggaggaatca
     2821 caatgagaaa aagtaaagca ataatgattg gtgccggtat tgccaatatg gcagcggctg
     2881 tttatttgat tcaagaaggc aaatggaaag gggatcagat caccttttat tcattggatg
     2941 atcacggttc aaatgatggt gcaccgaccg acactgtagt ggatgaatat tggaataaaa
     3001 accatccatt agaaaaccaa aaaggctata ttgctcgagg cggtcgcatg cttaattacc
     3061 gtacctatgt agatttgatg gatctgttaa gtcgaatacc ttctgttact gagccaggga
     3121 tgactgctga agaagatacg agagattttg atgcaaaaca ccgaaccttt gacaaagcac
     3181 gtttgatgga aggtggcaaa ggaatcattg atggcggaaa actgggattc aataataaag
     3241 accgtattct tctgactaaa ctgattgcta tgcctgattc agaagaagaa aaactagaca
     3301 atatcactat cgaagaatat ttcaaagatg atccacactt ttttgaaaca aacttctggt
     3361 ttatgtggga aacaacattt gctttcagaa cacgtagttc tgctcaagaa ttgcgtcgct
     3421 atatgcatca aatgatttat gaattcactc aaatcgaaca tctagtgggc gtcaatcgaa
     3481 cacgttacaa tcaatacgaa agtattatgc ttcctttgat cgagtacttg aaagaacaag
     3541 gatgcaaaat cattttgaac cgccgtgtca ctgactggga attcaaagaa acaccgatgc
     3601 aagatgaaat cactgtgact ggtttgaaaa tgaccaatac actgactcaa gaagaagaac
     3661 acgttgtggt cgatgaagat acagcagtta ttttcactaa tgggtccatt acagattcag
     3721 ctactttagg agattacgaa acaccagctg tagaaaatat ggattatggt gcagcttcta
     3781 gtctctggaa aaaagccagt gaacgtttct acaacttggg aaatcctgac aaattctttg
     3841 ctgatcgaga tgcaagcgaa tgggtcagct ttaccctgac gacgaaaaac catttgttgt
     3901 tgaatgaaat cacccgtatc acgactcaag aaccaggaaa tgccttgaat tcatttattt
     3961 caaccacacc gatcacgccg ttaggccaaa aagatgtcaa tatgtctatc gtcgtgcatc
     4021 atcaaccgca ttttacgtct cagaaaccaa atgaaacagt tatttggggt tatttccttt
     4081 atccaagacg acgtggcgaa tttgtggata aacagtatat taaaatgaat ggaaaagaaa
     4141 tgctagaaga actgattgga caactttcaa aagtagatcc tggaccagtg aatattcgtg
     4201 aaaaagaaac agaaattttc gacagcgtaa taaataatat ccctgtctat atgccttatg
     4261 cttccgcgtt gttcaataat cgtgccaaaa gcgatcgacc aaaagtcatt cctaaacatt
     4321 cgaccaatct ggcctttaca ggagaatttg tcgagcagcc ttatcagatg atctttactg
     4381 aacaaagtgc tgtacgttct ggagaaatcg ctgctttcca ttttgcgggt atccctatgt
     4441 cacgtcttgt caaaacaccg cgttacgaca aagatattcc tactctagct cgtgccgcaa
     4501 aaaaaatgtt tgaataatca agaggttgtg aaaaagctgc cctgcatcaa gtaataagaa
     4561 caaccaggct aaaacagctt cttatgtttt tgatttggtt ggacttatta ccgcagatgc
     4621 aagcttttga acaccgttta ccaagaggtt gtgaaaaagc tgccctgcat caagtaataa
     4681 gagcagccaa gctaaaacag cttcttatgt ttttgacttg gttggactta ttaccgcaga
     4741 tgcaagcttt tgaacaccgt ttaccaagag gttatgaaaa agtcgtttag tttcgagtat
     4801 gaagaaaaat tttgtgaaaa tggttcctca cgtttttgca taaatttgac ttaataccga
     4861 gaaactgatc ccttctgtca taacctcttt ttatttatgt ctgtttcttt ttgaaaacaa
     4921 ccattttttc aacgtttact ctcttgccaa tccaacatca tctaacagat acaactattt
     4981 caatgattac cattacacta aaaaatcgga aactcacctc tccgaacaca aatacataag
     5041 actatagaat gtttcattta agaaaaaaag cgtttcatta tcaaaaaggt aagatctcct
     5101 ttaaaatgaa attatctgta gtactaataa tgcagacaat tttatgaatc tgaaaggagc
     5161 atctccaatg aaagcagtca cttggcaagg aaaacagaaa atggaaatca gaaacgtaga
     5221 tgatccaaaa atattagaac caacagatgc aatcatccgt atcacagcaa cagccatttg
     5281 cggctccgat ctgcatcttt accatcatgg tgaagcagtt ttggaaaaag ggtatgttgt
     5341 aggacacgaa ccaatgggaa tcgttgaaga agtgggatct caagttcaaa cattgaaaaa
     5401 agggcaacgt gtggttatcc cttttaatat tagttgtggt cattgtcatt tctgcctgaa
     5461 tcacatggaa agccaatgtg atgaatcaaa tccagatcag ttatatggcg ggcttttcgg
     5521 atttggcaag ttgaacggta atcattgggg tggtcaagcg gaatatctaa gagttcctta
     5581 tgcagactct acttcatttg ttgtaccaga taatgatctt cctgatgaaa aagttttatt
     5641 tctatcagat attttgccca cagcttattg gagcgttgaa aacgcaggag taaaaaaagg
     5701 cgatacagtt gtgattctag gttctggtcc agtcggtcta ttcgctcaaa aattcgctgt
     5761 tatggctgga gcagagcgcg taatcgcagt agatccagta cagcaccgtc tagataaagc
     5821 ggctaattac aatggggttg aaacttattt cttagaagac acggcacaag ctggaacaga
     5881 attgtatgaa ctggctaaag gtggcgcaga tgtcattatc gattgtgtag gaatggacgg
     5941 attagagcct gtcaaagaaa aagcgaaaaa tttagtaagc ttacaaaacg gcacaatctc
     6001 tccattacag atggcatcgc aagctgtcaa aaaatttgga acagtccaag taactggtgt
     6061 ttatatgact ccagcttctt cttacccgct gcaagaattt tttatgcggg atatcgctgt
     6121 caagcatgga caggcaccaa ttatccatct aatgccaaaa atttacgaaa tgattgcaga
     6181 aggactattc gatcctacac aaatcattac tcattcgctg ccactatcag aagcagcaca
     6241 agcatatgag atctttgaca aaaaagaaga taaaaatata aaagttgttt tgaaaccttg
     6301 aattcagtaa aaaatacagg tgattttctt tatgcccaaa atcaaacgaa atacccatga
     6361 gatcgaaata ggaaaagaag aagatatcga aatacgagga cgtcgcttcc g
//
LOCUS       DAJSMK010000108         6322 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.114, whole genome shotgun sequence.
ACCESSION   DAJSMK010000108 DAJSMK010000000
VERSION     DAJSMK010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6322
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.114"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(99..1229)
                     /locus_tag="ON488_002356"
     CDS             complement(99..1229)
                     /locus_tag="ON488_002356"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HCR3232499.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="ON488_002357"
     CDS             complement(1878..3080)
                     /locus_tag="ON488_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR3232500.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="ON488_002358"
     CDS             complement(3140..3343)
                     /locus_tag="ON488_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HCR3232501.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="ON488_002359"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="ON488_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="ON488_002360"
     CDS             4880..5692
                     /locus_tag="ON488_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232502.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1879 a         1299 c          997 g         2147 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata ag
//
LOCUS       DAJSMK010000109         6301 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.115, whole genome shotgun sequence.
ACCESSION   DAJSMK010000109 DAJSMK010000000
VERSION     DAJSMK010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6301)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6301)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6301
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.115"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(67..1545)
                     /locus_tag="ON488_002361"
     CDS             complement(67..1545)
                     /locus_tag="ON488_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232503.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1843..2778)
                     /gene="murB"
                     /locus_tag="ON488_002362"
     CDS             complement(1843..2778)
                     /gene="murB"
                     /locus_tag="ON488_002362"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HCR3232504.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2851..3771)
                     /locus_tag="ON488_002363"
     CDS             complement(2851..3771)
                     /locus_tag="ON488_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HCR3232505.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3884..4636
                     /gene="xth"
                     /locus_tag="ON488_002364"
     CDS             3884..4636
                     /gene="xth"
                     /locus_tag="ON488_002364"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HCR3232506.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5500..6033
                     /locus_tag="ON488_002365"
     CDS             5500..6033
                     /locus_tag="ON488_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HCR3232507.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT         1902 a         1203 c         1048 g         2148 t
ORIGIN      
        1 ccttttcttt gaaaaaaaca taaatcagct aataaatatg tgagacaaag ctgccatcca
       61 taaatactag ctgatttttt cagttaaatg tctatttttt tctctgatga tggtatttcc
      121 aaaatattcc cagtcatctg gagtcggtgg atttttccaa attatctgtt ctttattaaa
      181 tttttcaagt aaacaatcag ataaataaat attcgtacga gaagtgattc gactctcaat
      241 cacaatattg taatttttaa atcctttcac ttgagaaata atgtaatcgg tataagcaga
      301 tccttgcgaa aaatcaatac agacatgaat cggtgcttca aaatatgata ccggacaaat
      361 accgaccaat aaaaagagat aatcataaaa taagcgaatc atgaaacgtt catcttttcc
      421 caagaaatag cgtttattct cttgtatgac cttttggatt gctgtactga atattggata
      481 cgtctcgaag aaaaactgta gctgcttttt agacgtaaag ctagtcatct caaagtcgaa
      541 tatccaattt tttcgattga catgcatcat acccatacga agttcttttc gtatatatag
      601 tctttcttct tcagagattt caatcgaaaa tggtaattga tcaatcaatt ccactgacat
      661 tttttgacta atcatgtgga tatcatgaaa atgagcttcc gcaagtccaa atgcgccatc
      721 taattcaaat tcttcttccg tgatcaaaaa caacatgata taagaaatct catcaatgat
      781 ctgctcttta gggatatgaa gaaaagaaat atgtgataaa tccttgatga tcttcattcc
      841 ttctgagctc ttaaagtatt catctgaaaa gaaacgtttt ccgattggtt gattcccata
      901 ggccctcaac aaactaatag tggttagcaa attgaatttg attcgttttg ttgcagacag
      961 ttttaaattg aacagatatt caaaatattg cacgatactc tttgcttcat tcatgacgct
     1021 ttctctaaat ggcatagaaa aaccattaaa gaccccgaaa tataccccaa ataatacgtt
     1081 ccgtatgttt atttcttccc caactaatat gtttttcttt aactttattt gatgctgttc
     1141 aagaaaagag actaattctc ttctttttac ataggctctt gatatgctta aaaaatgatt
     1201 ctctgcaaat ttttcgatcg ttacttttga atccacgatc tccgttaaca gtcgagcaat
     1261 ttttgatcgt tgaaagtaga ttcttcttaa atttttgata tccgtcaaat tcagacgttc
     1321 gacatggatc tctgcttctt ctgaaatttg gatctctggc tttgttttga attcagtaaa
     1381 ttctttattt aattctatga tataatttct tgttttaaat ttagacaaac ctaatgtttc
     1441 atataactta ggcagcacta cataattctt tttctcaaat tctaaatatc tagctagcag
     1501 cagtttttct ctatcttcct cttctataag gtaatccaac ttcatatcct acacctcaaa
     1561 aaatgcctca taccaattac ttgatatgca gatgaaagtt catcttttca cctatactga
     1621 ttttatgatg gattatgctt gttttttcat cagttattct cattttttat cttttttttg
     1681 agaatattgc aaaaaatgga aaaatttatg aggaaatatt ctatattttt tgttttattg
     1741 tgttaaaatg tacaagattt gcgccatttg cgtaaacaac cacaaaaaag agcaggacgg
     1801 ccaccgtcct gctcttttac ttattttaag ttccattact tattaattgg ctaaacttct
     1861 gcttgtttct gatattgctt gtttttctcc aatgatccgc acttctgttt ctaaagacac
     1921 atcaaatttt tctttgatta cttcttggat gtgcgcaatc aattcaatat aatctgtcgc
     1981 tgtcgcatga tcgatattga cgatgaatcc agcatgtttt tcagagactt gtgcaccgcc
     2041 ccatttcagg ccttgcaatc ctgcttgttg gatcagctga cctgtatagt gtcctactgg
     2101 gcgcttaaag acacttccgc atgaagggta ttctaatggc tgttttgatt gacgcaattc
     2161 ggtcaactca tccattcttg ctttgattgc ttcataatcc cctgtttgca aactgaatcg
     2221 agcttccaat acgatagcac gtaattcttg gactttactg tgacgataag aaaataccat
     2281 ttcgtctttt gtcaaagttt tcaatgttcc atcttcaagc aaaagatcca cttcagcaaa
     2341 aacatctttg atctctccgc catacgcacc tgcattcata taaaccgctc caccgacact
     2401 tcccgggatg ccgcaagcaa attcaaatcc agtcaatgat tctgccaaag ctgcataagt
     2461 cgtatcaatc agtgaggcac ctgcttccgc aatgaccatc gttcctttga catgaatctg
     2521 tttcatttca gtcagcatga tgactacacc gcgaatcccg ccatcttgaa cgatcagatt
     2581 gcttgcattt cctaatacca tccaaggtat atcatggatt cggcaataat cgatgatttg
     2641 ctttacttct tcttgttttt tcgggaatgc aaggacatca gctggtccac ctgttttcgt
     2701 aaacgtatag ttcatcaatg gttcatcaaa caatatagta atcgtggcta agctttcaac
     2761 tatttcttct ttattcactg aggattttcc tttcttttct caaacgtcct cattattcta
     2821 tcacgcttaa tacaatcttg ccagtcttgt tcaaagttga tgacggtagt gatctttaag
     2881 cacttcctca cataattcat gacttcttac aacttctttt tgtttaagca attctgtttc
     2941 cgatttacct aaacggatct gagaaaagaa ggcctctacc attggctcaa acccgcgttt
     3001 gactagcgtg tttgtccagt cgccaaattc tttcactttt tttccatcag catcttgaat
     3061 gacaagctgg gtcagatcgt ttacttcata agtaccattt ttacttgtta cttgatattt
     3121 ttctatatta gcgccacttg ctaaatccat cgttaaaata gccgtttgat tttgtgtttc
     3181 taattgtaaa atggcatatt ccaaaaattc ctttgtttct cttatctggt attttgttct
     3241 caaaatgggt tcatctaata aatacacagc tgtatcaata agatgtaaaa acaaatcata
     3301 aaggacgaac tctgtcgttt cttttgccgc tattcgattt ttttgcaggt ggatcaaccg
     3361 cttatctggg atacgtttca attcttctac cataggagca aagcgccggt tgaaaccgat
     3421 catcaaaatt atttggttct tatcagctaa ttcttgcaat tcacgaactt catttagatg
     3481 gacactcagt ggtttgtcaa tataaacatg gataccattt tctagacatt ttttggctaa
     3541 ttcataatgt acttttgttg ctgcgtggat catacatgct tcgatttttt cttctaaaag
     3601 ctcatcgatc gtttcatata gatgttggaa cccgtactct ttttgaattc tttcttttgt
     3661 ttctttattt cttgttgcaa aataaaaatc aagtgttcct tgttttttcg cataagttgg
     3721 taaatatgct ttttctgcga tattccctac accgattaca ccaatcttca tctactttcc
     3781 tcctggatca tttagttact ttcatcttac accatttttt actaaaatga ggtacaatag
     3841 tatcgcaaag gtaaggaaat taattcgaag gagtgtgctt ttattgaaat ttatctcttg
     3901 gaacgtaaac gggcttcgtg ccatcgtaaa taaaaatttt ttagaagttt ttcatgagtt
     3961 agacgccgat tttttctgtc tgcaggaaac gaaactccaa gcaggacaaa ttgatttaga
     4021 tcttccaggt tattatcaat attggaatta cgcggaacga aaaggctatt ccggcacagc
     4081 gatttttgct aaaaaaccag cattgaatgc cacttacgga atgggtatcg atatccatga
     4141 tacagaaggc cgtctgatta ctttggaata ttccgatttc tttcttgtaa cctgttacac
     4201 gccaaattct caaagcgaat taaaacgttt agattaccga ttagaatggg aagaagcctt
     4261 ttataattat ttggaaaatc taaaaaaaca aaaaccagtc atcgtgtgtg gggatctaaa
     4321 tgtcgctcat caaaagattg atttgaaaaa ctggaaaacg aatcaaaaaa atgctggatt
     4381 cactccagaa gaaagagcgg ctctttctcg actgttggat aacgggttta tcgatacatt
     4441 ccgttatttt tatccaaccc aggaaggtgt ctactcttgg tggaactacc gattcaattc
     4501 aaggaaaaac aatgctggtt ggcggatcga ttactttttg acgagcaaag atttagagcc
     4561 aggactagct gatgcaaaga tccatacgga cattatgggc agtgatcatt gtccagtaga
     4621 attagatttg aaataaagag gttgtgaaaa agtcgtttag tttcgagtat taagaaaaat
     4681 tttgtgaaaa tggctttcca cattttgcat aaatttggca taataccgag aaactggctt
     4741 ttgaacactg tttatcgaga gattgtgaaa aagctgtcct gcatcaagta ataagaacag
     4801 ccaaacaaaa atagttcctc atatttttcg tttggttggg cttattaccg cagatacaag
     4861 cttttgaaca ccgtttatta agaggttgtg aaaaagctgc actgcatcaa gtaataagaa
     4921 cagccaaaca aaaatagttc ctcatatttt tcgtttggtt gggcttatta ccgcagatgc
     4981 aagcttttga acaccgttta ttaagaggtt gtgaaaaagc tgcactgcat caagtaataa
     5041 gaacagccaa acaaaaatag ttcctcatat ttttcgtttg gttggactta ttaccgcaga
     5101 tgcaagcttt tgaacaccgt ttattgagaa gttgtgaaat cagcgtcctg acctgagtat
     5161 tagagaaaca aatggcaaaa tagttcctca tattttgcta ttttttgagc taataccgag
     5221 ggtcagctga ttgaacaccg tttagtggag aagttgtgaa aaagtcgcct actttcgagt
     5281 cgtaagaaat ttttttgaaa atggttcctc acaactttgc ataaatttga cttaataccg
     5341 agaagtcatg atccccatct aactccaaat cacaaggaat gagttcaaaa actagctttt
     5401 ctcaacaaat attacataaa aaattctatg ttttttgtta aatttatttg cttttttcaa
     5461 aagtatgtta cagtaatttc ccaaggaggt tttacagaaa tgaattttgt tgccatggat
     5521 tttgaaactg ccaatcatca gccttatagt gcttgttctc ttgcgctagt catggtaaaa
     5581 aatagccaga tcgttgatga attctataca ttgatacagc ctgagactcc ttttttctgg
     5641 cgaaatgtcc aaattcacgg aatccatcaa gaagacgtac gcaatgcgcc gaaattccca
     5701 gaagtctggc aaactatcca accatatttt caaaaaaatc gtttagtcgt tgcacataat
     5761 gctgcttttg atacaaaggt cttagcggga tgcttagatt attatcatct tgaacagcct
     5821 aattatcttt ctttatgtac agtgaaaagt agccgtcgcc tgtttcctga atttccaaat
     5881 catcgattga acactgtgtg cgaaaatttg aacatccaat tagatcatca ccatgatgca
     5941 ttggaagata gtcgtgcatg tgcggaaatc ctgctttatc aagaaaaaaa attcgggaca
     6001 gatccattga aaaaacttgt gactataaag taaaagaata cttatgaaac acacaaagag
     6061 gtcgtgagcc tgccgtttca ctccgagtca caaggagcaa tttcaaaaaa tagcttctca
     6121 tgtttattaa atattgtgac tggtgaccga ggagctggca ggagaacacc gtttattgga
     6181 gaggttgtga aaaagctgtt ctgcatcaag taataagaac agccaaacaa aaatagcttc
     6241 tcatattttt catttggttg gacttattac cgcagatgca agcttttgga caccgtttac
     6301 c
//
LOCUS       DAJSMK010000110         6238 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.118, whole genome shotgun sequence.
ACCESSION   DAJSMK010000110 DAJSMK010000000
VERSION     DAJSMK010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6238
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.118"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..1251)
                     /locus_tag="ON488_002366"
     CDS             complement(<1..1251)
                     /locus_tag="ON488_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCR3232508.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
     gene            complement(1456..3264)
                     /gene="pepF"
                     /locus_tag="ON488_002367"
     CDS             complement(1456..3264)
                     /gene="pepF"
                     /locus_tag="ON488_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HCR3232509.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(3440..4438)
                     /locus_tag="ON488_002368"
     CDS             complement(3440..4438)
                     /locus_tag="ON488_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HCR3232510.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(4664..5317)
                     /locus_tag="ON488_002369"
     CDS             complement(4664..5317)
                     /locus_tag="ON488_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HCR3232511.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(5649..6047)
                     /gene="spxA"
                     /locus_tag="ON488_002370"
     CDS             complement(5649..6047)
                     /gene="spxA"
                     /locus_tag="ON488_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCR3232512.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQKLLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1846 a         1277 c         1022 g         2093 t
ORIGIN      
        1 tttgaaattg taaaagttgc gaaagccgta cgcattgcgt tttaatactt tgatgtggtt
       61 gtttaagcat tccaatggtc cgtttgaata gctgtagtga agcgcatttt ggatctgtgg
      121 cagaaacttt ttaaacgttc gtaaagtggt tgtataggtt tctggcagac cgctaatgtc
      181 tctagttaaa caatcctcaa atagtgactg atctcttttc tttaccgcat aaagaatgtc
      241 ttggtataac tgatagcctt ggcgtaagtt gggacaagca gctaacagtc gatcggcaat
      301 ctcactttca gtcaaataat ctttaaaact ggcacgccaa acccgttttt catagtttaa
      361 ctttgcttct tctttttgta ggagtttcca atagcgcttc aattttttcc ctaaccctcg
      421 ttgagagtgg gaatttcctt taagtcgtac cgtggtttct ttcactcgat gattcaagaa
      481 agttctgcca atatgttgga cgatgtggaa acgatcgatg atcaactgag cattcgggaa
      541 aagctttttc accaacgaaa cataaggcgc atacatatca ataacaatca attgaacggc
      601 ttcacgagtc gctaatgaaa accgagaaaa atagcgttct aaataaggca agcgtcgatt
      661 ttcgacaata tccaataatg catggctttg tccgtccatc atgataaaac tcattgcact
      721 ggcaacactt cgaaccgatt tgaattcatc aaagcataag acctttggca aagtctgttt
      781 gaaaggattc aatgggcggt agaatcgctt catgacacga tagaccgaag aagtggaaat
      841 atttttctga cgagcgattt ccgtcatgga agtattctct tttaagcgag caatgacaga
      901 ccaacgaact ttttgactaa tgaaacagtg tttttcagca acagaggtat ccgctacgaa
      961 tgttctttgg caagacttac atttaaatcg ttgtttcttc agctccagat aagtgcgata
     1021 ctcagacaca tcattcagta acaaccgaac ggttgtcgtc ccccaacgaa tgatcctaga
     1081 ggggacgaca caaagacaat gggaacactc ttctggcttg tacagaagag ttcctttgta
     1141 aatcaagcaa atttgccctt tgtatttttc tttagttaaa caattttcct cgaaatagat
     1201 atttaggtct agaatattta gggtatcttt gataagctga gtatgagaca tcttgaatcc
     1261 tcctatgaat tggtagccaa attaattcta aaggatttca gggtgtcttt tctatatttt
     1321 tttatacaaa aaagatgttg gtgaagttca ccaacatcaa aaagtataga gccttaaaaa
     1381 aatacgtcga ctcccttaca agagagccga cgtatttttt tcgtttctat tcgagaaaat
     1441 caaaaataga aagccttata aacgatcgat caattcttct aattcattta gacgttgttc
     1501 aaacatcgac attgcatctt caatatatgc agcctgtgtc atatcaactc ctgctttttt
     1561 cattacttcc acaggataat cgctgttacc tgcttttagg taagccaagt agttctctag
     1621 tgcctctggt tcctggttta gtattttctt cgccagtgct gaagcagcag aaaagccagt
     1681 cgagtattgg aaaacatagt aattataata aaaatgcggt atccgtgacc attcgaattt
     1741 aatttctggg tcttcttcga ctgctggacc ataatatttt gcattcaatt taccataact
     1801 atcacttagg tattcactag tcaatggcac acctttttca tcttccgtat gcatgaaatg
     1861 ctcgaattca gcgaattgtg tctggcggaa aactgttcct ttaaacccat ccaagtaatg
     1921 gttgagtaca taagcccgta cacgagggtc tttttctgtt tccaataaat actccgttag
     1981 gatattttca ttcgttgtcg aagcaatttc tgctaaaaag atggagtagt cgccgtacac
     2041 ataaggctgg ttcgaacgag tgaaataact atgaacacta tgtcccattt cgtggacaag
     2101 cgtaaatagc tgatccagcg tatcatgcca attcaataaa atatatggat ttgtgtcata
     2161 gcttcccgaa gaataagcac cgcttcgttt ccctttattt tcgacaacat cgatccaacg
     2221 ttcagagaat gctttttcta cgatggccat gtattcttca cccattggtt tcagtgcttc
     2281 taaagctttt tcttttgctt cttcgtacgt aaaggtaatt ggagcttccc ctaagaccgg
     2341 tgtataaaga tcatacatgt gcagtttttc cacttctaat aaacgtttcc gtaattccat
     2401 gtatcgatgt aacaaaggca aatgcttgtt taccacgtct accaaagtat cgtatacact
     2461 ttcaggaata tgattattgc tcaaagacgc ttctctggca gagctgtaat tacggacttt
     2521 cgctttaaaa ttatgtcctt ttatatgtgt gcctaaagta gaagcaaatg tatttctaaa
     2581 ttgttcgtaa acactgtaca accccttaaa tgctgcttcg cgcacccttc gatccgtgct
     2641 ttctagcaac tgaccataca cgccatgaga taattggact atttcaccat tttctccttc
     2701 aatcgttgga aaaactagat ctgcattatt caaaacagca aatgtatcac ttgaagcatc
     2761 aaagatttca cctgctccag caagaagaga ttcctgctca gcagataaga catgggctcg
     2821 attatctact atttgctgga tataatggcg atagacttcc aattttggtt cttctttgaa
     2881 atattgccaa atctggtcat ctgacaattg caatatttct ggttcaaacc aggaaacggc
     2941 ttcactaact ttcgaaaaca gactgcttgc tcttgcataa agcgcttggt aatctgtatt
     3001 tccagtgtct tgatcgtttt taaggtgcgc atatacataa atgacttcag tttggcgata
     3061 aaccctcaat acgaattcaa tcgcatttaa aaattgagaa gcgccttgat caagtgttcc
     3121 tttgtgtttt tcagattgtt ttaactcttc tgataattcc aaatatttct catcaaactc
     3181 ttggtcgctt gaaaagatct tggtcaagtc ccaagttaaa ttttcaggca attcttctcg
     3241 ttttggcaac tgctttactt ccatgaaatc cactcctttt cttcccttag ctctatctat
     3301 caaaatagat catagtctaa catccacatg tcacagcatc taacttttct actcattcat
     3361 gtgtctgctt ccatcaattt tagcataact aaatcttgtt ttacatagaa aaccgattcc
     3421 tagcctattt ttatacttac tattttttca aagaagacaa gtgtatgcat tcgttaaaaa
     3481 actgctgata gaccatctct tcatcaatca taggaaaaag ccattccctt ttatgttctt
     3541 ttatttggca aagccatgag ttgaaatcag gaactttctg gttttccaag gcttcttcgt
     3601 acaacattcg ataaagaaaa acctgttctt gtaaataaaa gaaaaaccga cttttttgat
     3661 agatccacga tgatagatgc aaaagatgtt tatgacgcaa gtagcattgt tcttgtatgg
     3721 atactgtatt cttttgcttg tgaataagtt ggcgtgtcag ccatttcttc ccatcttcac
     3781 tcactttttc tatttttttc atttggttca ttttaatttc gttactagtg aatatttctt
     3841 taaggtccct actagaaaaa gtccagcagc tactgcaaaa ggaaatatgc cctgatacag
     3901 tctctgtaat atgatgatac aaataaagct tttgtttctt gagatcagct ttccagcaat
     3961 gcactcctct ttttctatta tagtagcagc aacttttttc tatcaatgag aattgcgatt
     4021 gtccaagaaa agaattacca agtatccacc atacttggta actgttattc aaataatttt
     4081 gggttctttc aataaatctc tggtgagaca gtctagaaca ttggatttct attgctagat
     4141 tcgccaacaa aatatccggc ctttgccgca acctcggcaa ataggcttcc aaaaatactg
     4201 gttctactga ctgtcccagc caatccatga agcattcctt taactgtaag tgctcttttg
     4261 attctctttc actaaagacc gaacagttat ctgatttttg atgggcaaaa tgagcacatt
     4321 ttttctttcc ctttttcaaa atcactcttt ttcgacagcc acgacaataa tatttctttc
     4381 ctttttctgc atgtttagca aaacagcact tattatattc attcattgca agcagcattt
     4441 ttctccctct gaacttattt acgtctaaga atttatttac acgaaaaaag agggcgtgaa
     4501 aaagctattc tgcatcaagt aataagaaca gctaaacaaa aatagttccc aatatttttc
     4561 gtttggttgg gcttgttacc gcagatgcaa gcttttgaac acatttatac gaaaaaaaga
     4621 ctgcgacaca atttttgtca cagtctctta ctataatgct gatttataca aaataaaatt
     4681 tcgttcgctc gatagcatta cgcgccatca gacattgtcc atattcattc aatgtttctg
     4741 gtgtacgatc gctcttttca gcaaactcca aaattcgagc aatctgattc tctacatccg
     4801 cttggttgag attttccatc cagaagtgaa cgactaggta atagcgctct tcgaataaat
     4861 acaaatcagt ccaagcagac tctagttcga catctgttgc aagttggatc acttgttcaa
     4921 aatcttcaaa agcaaaagtt gcttgtcttt cctgttcttc tagggcgctt ccagataatt
     4981 cttcctccgg atcgctgcca ataatctgct gacgaagaaa gtcactcaca tcttctgaat
     5041 caacagtaga atcttctgat tgagaaattt cttcatccgg aagattttta ctgataaaca
     5101 gttctaatcc gtctcctttt ggcaaaactt ggaaagtgac agcttcgctt cctcggaact
     5161 cctcttcgat atcaacttct tccaaaatac tataaaagaa attttcgatt tctttgtgat
     5221 tgccaagtaa atccaaaaat gaaacgcccc gttcctctaa atcttcatga ccaattagta
     5281 cacggatcgt attttcatta atatgttcca tttccatttt gctacacctc actttgccac
     5341 aatgtttaat atagattcat tgtagcgaaa tcagcttaaa tgtaaagaaa aaaaatctcg
     5401 ctgttaagcg aatttaataa aaccagcgga tttttcaacc tttcaagcta tcttatttaa
     5461 ctataacatt tttggcagac gaatactata tagccgactt ttcagctaat tttccctctc
     5521 tatttttcgt gcaatcatca tcatctacta cctttttata catctaatca agaatacttt
     5581 ttgtaaaaac aaaaaaactt ggaaaaacta tctttgtaat agtcttttcc aagtttcgta
     5641 ttatccttct ataatccagc catcaattgt gcttgacgta attctaattg tcgtacatcg
     5701 cgcggtagga accgacgaat ttcatcttca ttaaaaccaa cttgcagacg tttatcatca
     5761 atcatgattg gacggcgaag caatccagga ttgttttgca caagttccaa taatttttgt
     5821 aacggcagat catctaaatc catgttcagt ttttggaata ctttggaacg tgtcgagatg
     5881 atttcttctg ttccgtcttc tgtcatttgt aaaatcgctt ttaattcaga actgttcaat
     5941 ggttctgaaa aaatattacg ttcaacaaat ggaatctgat gttcttgcaa ccacgcacga
     6001 gcctttctgc aggaagtaca acttggggaa gtatataatg ttaacaacgt gcaccactcc
     6061 ttttcgtgat aagaatcact tttttgtaac agaagatcat aataatctcc catctgtttc
     6121 tattatacat aatcaacttt taaatagcta cctttttttc ataatttttt taaaaaaatg
     6181 aaagttatct aaggttaata tacagtaaaa ccagcattct cgcttttttt atcattta
//
LOCUS       DAJSMK010000111         6185 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.119, whole genome shotgun sequence.
ACCESSION   DAJSMK010000111 DAJSMK010000000
VERSION     DAJSMK010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.119"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..687
                     /locus_tag="ON488_002371"
     CDS             <1..687
                     /locus_tag="ON488_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232513.1"
                     /translation="AFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFLG
                     CIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTTC
                     YEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKIE
                     EACSDLFGDTNPWFASEEEKKEKQQSVTYERYEILLQQATNMQNPTKKETALNYLKSV
                     KEWLDQQQQN"
     gene            complement(808..894)
                     /locus_tag="ON488_002372"
     CDS             complement(808..894)
                     /locus_tag="ON488_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCR3232514.1"
                     /translation="MFELFICPLLVGVCVSLFSYWLNNRNKK"
     gene            1551..2288
                     /locus_tag="ON488_002373"
     CDS             1551..2288
                     /locus_tag="ON488_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015060391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCR3232515.1"
                     /translation="MSNDIVRYNNGLNSVPLRKFTPIDMDLFWGICSKMKRKGTKEEI
                     FTFKQIKELIDYNINARGDRFANDLIKMSKKIITLSFIYEDEKTYEQLNLFQKFKIDK
                     VNETLLIKVSEEFEYILNSIGTNFTRFELENMTNLKSSYVKELYRQLMAHKDRRSKKG
                     HWFVKIEDFRALLAIPESYRMRDIDKQIFAQAKKEFLNVNSTHPAIFKTFEIKKIKAY
                     KGNKIGSLQIYFEENIPSITLDNWLEK"
     gene            2316..2855
                     /locus_tag="ON488_002374"
     CDS             2316..2855
                     /locus_tag="ON488_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HCR3232516.1"
                     /translation="MQPKETFTIKELSELFEISRQAISKHVDKLDPSLLAKNERGYKV
                     VLRSGVLQLASNLGNQRLLYRLHEYEQENDKNVYISSKNVIVNELLDKLREENEFLRE
                     QLSLKEQNNSNMQKLLDQQQQLTLQANQQIEKLQEQLQLAYTEETPEDESTTILSEET
                     ESIEKHTKKKKQKWWQLWK"
     gene            2871..3041
                     /locus_tag="ON488_002375"
     CDS             2871..3041
                     /locus_tag="ON488_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232517.1"
                     /translation="MTRKNLLFGSILLGILGFSPMLLSVINKGNKHGELKLNPNYYNS
                     PNEELFVKQTDK"
     gene            complement(3354..3815)
                     /locus_tag="ON488_002376"
     CDS             complement(3354..3815)
                     /locus_tag="ON488_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232518.1"
                     /translation="MEDLGSKLRELRVKKGYTQEYVARKFNVTRQTISKWENNKTTPD
                     IETLKKICEFYSTNINSILNEDNSKNKKNNLLVLTAIIFNIFVTILGLFELIQMNFFS
                     FTHGIFTWFALSGLIVIDILNYFYIYYSYLKNEKFFYTMFFPLVILIILLS"
     gene            3948..4322
                     /locus_tag="ON488_002377"
     CDS             3948..4322
                     /locus_tag="ON488_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HCR3232519.1"
                     /translation="MKKFLCLSALMGVLLTSGGIASATEALNLDVPEDHTAIYGGGME
                     ATEEGFSSSKLRYAAGGGDFNCGVNGFKVYANYYHARAKHSATAKNGRGGQVRSVQKA
                     GVRAYATCNATLTGNTGWWNVY"
     gene            4376..>6185
                     /locus_tag="ON488_002378"
     CDS             4376..>6185
                     /locus_tag="ON488_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232520.1"
                     /translation="MLKKINAVLSLFVCITILFFSTNVINGIKTSEALYKNTAEIHMQ
                     YKDDMDFNSYINALYEISTQENINISQYSFTAVNQLTILATNPNANKHWKFSKKNILA
                     RNDSKVHYTNNKNSKYQLKLPNNFLNINIYPFSHVENIGLSEILYVQGNSNKLIPVLK
                     KYGTPTISNINQSDTFQINTNIVLVICYLSIFIVITTIIFAFSKMKEITLKKMLGYNS
                     FDTIKDSIKELNLLFCSLIITFILSIFLSIYYSNENFFLSFLLCSIFHFIISFLFIIV
                     TLSIYHLSSIKNYLKNSRPLKLNLCILNICLFLSMILLLIASTKVINTHNEAENNSLK
                     YWERTTNLYKTNITNQLNRNNTVEENNYLKKASKFVYKIQKNYKTFIIAPYNYATIQE
                     NNKEFFIGQKVYPNFEDYVSQPAGAGICVDLNYLKYYNPISFEESTDLNLINSDPLTT
                     YILVPKKYKEYAKMIEKNYLEDIQFRLEDSPPQAPYKNPNLKNLKIKLIFVNNNQKYF
                     SFNTLYGKAKDNYTITDPIVRVINPEITESLFWGNILTSDGGLFFDQKHTSNQNFFNQ
                     INPYIKEFNLENIINFSYSVFQETGELLSQKKVNKLN"
BASE COUNT         2395 a          898 c          930 g         1962 t
ORIGIN      
        1 gcattttatt taccctatct actcattttt gttagtattt caggaagtat ttggctcatc
       61 tataaaattt ttcaaacaag atattcatta aaaggctcta aaattcgatt taagcgattt
      121 ttctttcttg gctgtatatt ttccttgata atcgtttcaa gcggcttatt cggcgtttta
      181 gagggaaata agcgcgtttc tagaagtatt ttattaggaa atgtcactca aaagtatgaa
      241 tcagcgcgtg ataaaaagaa aaaagagcaa gcattagcac aaaaaatgga agagtttacc
      301 acttgttatg aggaaatgaa cgatattttt gtgaatcaag aaaaacgttt gacggataaa
      361 aacatggaaa aactcactcg tctttatcaa aacttgccag aaaaacagca aaaagaggtt
      421 caagacaact atgagcgaac caaaaaagac gtgcaatatg taaaagatac aaagatagaa
      481 gaagcctgta gtgatctatt tggagacaca aacccttggt ttgccagtga agaagaaaaa
      541 aaagaaaaac aacaatctgt cacatatgaa cgctatgaaa tcttacttca acaagcaact
      601 aacatgcaaa atccgacaaa aaaagaaacc gccttaaact atctaaaaag tgtcaaggaa
      661 tggttagatc agcaacaaca aaattgaatt tgatttaaaa tcatgttaaa ctgaatgtgc
      721 aaatgatcaa acattagata cacgaaagcc ccagagaggt cggattctct ggggcttttt
      781 ttcaggttga tgtcgccttt attgatttta cttcttgttt cggttattca accaataact
      841 gaataaagag acacaaactc ctacaagaag ggggcaaatg aacagttcaa acattagata
      901 cacctccttc cagtcgcaag actgtcggat aggcgacaag ttattatatc ttaaaaaatt
      961 aaatttgtgt ggtgttttta agtatcactt gttttagggt tgttagggct tgccctgacc
     1021 gcctgtaagg cgcttctcga ctagattaag ggaaattaat caagaattgt cttagaacgg
     1081 cttagacaag ctttcagagt ctcacacctc ctctttgaac aacggtttta gcaaaggagc
     1141 cggaggcgac tgcgcagtat aatatgagag catagcgatc acaccttttt agcgaccgta
     1201 gggagcaagt tttccagttt agaaaaattc gcgaaccttt ttggaggaaa aagtaggagt
     1261 tttttaggcg ggaaattcaa tgtgctctta agatatactg ttagatatac tgttagatat
     1321 actgttagat atactgttaa taataactgt tagggattag caaccttatg ggagagtaag
     1381 tattgacata ggtagtgggg gataaattgt cacactatgg gggataaatt gtcacactat
     1441 gggggataaa ttgtcacact atgggggata aattgtcaca ctatggggga taaattgtgt
     1501 tttacatcct cttatgtcta tgataacata atttattgag gtgattttta ttgagtaacg
     1561 atatagttcg atataataat ggattaaatt ctgtcccttt aagaaaattt acccctatag
     1621 atatggattt attttgggga atatgttcta aaatgaaaag aaaaggtaca aaagaagaaa
     1681 tttttacatt taaacaaata aaagaattaa ttgattacaa tataaatgca cgtggcgacc
     1741 gttttgctaa tgatttaata aaaatgtcaa aaaaaatcat tactttgtct tttatttatg
     1801 aagacgaaaa aacatatgaa caattaaatc tgtttcaaaa atttaaaatc gataaagtga
     1861 atgaaacatt attaataaag gtttctgaag aatttgaata tatacttaat tcaatcggaa
     1921 ctaattttac tcgtttcgaa ttagaaaata tgacaaactt aaagagtagc tacgttaaag
     1981 agttatatcg ccaacttatg gctcataaag acagaagatc taaaaaaggt cactggtttg
     2041 taaaaataga agattttaga gctctattag caataccaga aagttatcgc atgagagata
     2101 ttgataaaca aatttttgcc caagcgaaaa aagaattttt aaacgttaat tcaactcacc
     2161 ctgctatttt taaaactttt gaaatcaaaa aaattaaagc ctacaaagga aataagatag
     2221 gatctctgca aatttatttt gaagaaaata taccttcaat taccttagat aattggttag
     2281 agaaataata cctaacaatt taggaggcaa ttatcatgca acccaaagaa acctttacaa
     2341 taaaggaatt atctgaatta tttgaaataa gtaggcaagc aatctctaaa catgttgata
     2401 aattagaccc gtccttatta gctaaaaatg agcgtggtta taaggttgta ttacgttctg
     2461 gagtattgca acttgctagc aacttaggta accaaaggtt actatatagg ttgcatgagt
     2521 atgaacaaga aaacgataaa aacgtttata tatcaagcaa aaacgtgatt gtaaacgagt
     2581 tgctagataa gttgcgtgaa gaaaatgaat ttttacgaga acaactttcc ctcaaagagc
     2641 aaaataattc taatatgcaa aaattactcg accagcaaca acagctcacc ctacaggcaa
     2701 atcaacagat cgaaaaactg caagaacagt tacaattagc ttatacggaa gaaactccag
     2761 aagatgaatc aactactatt ctttctgaag aaacagaatc gatagaaaaa cacacaaaaa
     2821 agaagaagca aaaatggtgg caactttgga aataactgga gggaacattc atgacaagaa
     2881 aaaatcttct attcggttct attttactag gaattctagg cttcagtccg atgttattgt
     2941 cagtaatcaa taaagggaat aaacatggtg aattgaaatt gaatccaaat tattacaaca
     3001 gtcctaacga agaattgttt gtaaaacaaa cggataaata ataaaaaaga ctgctctttc
     3061 gagcagccag ttaaaaaata atgagtgttt attcttgaaa aagcaacgcg cttatgaagc
     3121 gctaccaaaa atttatcata ttttatgaaa aataacaccc cagtaaaaaa tgactggtaa
     3181 aaattcacaa agaaacggaa agaagcaact gcagaaaatc aagccttaaa aagagctttt
     3241 gacctagacc aatgaaaaat cacaaagtga gcccctgtat cccttggtag agaggctact
     3301 tggcatagtc gacattatgt caactatgca attaaataac taactacttc atattagctt
     3361 aataaaataa tcaaaataac tagggggaaa aacattgtat aaaaaaattt ttcatttttt
     3421 aaataagaat agtaaatata aaaataattt aagatatcta ttactattaa tccagataga
     3481 gcaaaccaag taaatattcc atgtgtaaag ctaaaaaaat tcatttgaat caattcaaat
     3541 aaacctaata tagtaacaaa tatattaaaa ataatagctg tcaataccag taaattattt
     3601 tttttatttt ttgaattatc ttcatttaaa atagaattta tgttagtact ataaaattca
     3661 caaatttttt ttagtgtctc tatatctggt gttgttttgt tattttccca ctttgaaata
     3721 gtttgacgtg taacgttaaa ttttcttgcc acatattctt gagtataccc ttttttcact
     3781 cttaattctc ttagcttaga tcctaaatcc tccatttttt ctcctatgta aacgattatt
     3841 tacataaaat tttatcataa aaatactaac gcgccaaaaa agttctttat tttataaaac
     3901 acactaaaat aaaataattc tagtaaaaaa gataggagaa ataagttatg aaaaaatttt
     3961 tatgtctttc tgctttaatg ggtgtcttat taactagtgg aggaatagct agtgccacag
     4021 aagctttaaa tctagatgta cccgaagacc ataccgccat ttacggagga ggaatggaag
     4081 ctacagaaga aggattttct tctagtaaat tgagatatgc tgctggcggc ggggatttca
     4141 actgtggggt taatggattt aaagtttatg caaattacta ccatgctaga gctaaacata
     4201 gtgcaacagc taaaaatgga cgaggcggtc aagtacgatc agttcagaaa gctggagtaa
     4261 gagcttatgc aacatgcaat gccacactta ctggaaatac tggttggtgg aatgtttatt
     4321 aaaaaagaga gtttaaactc tcttttttat ttacatttga aaggaaattc aaaatatgtt
     4381 aaaaaaaata aacgctgttt tatcactttt tgtctgcatt acaatactat ttttttctac
     4441 taatgttata aatggtataa agacttctga agcgctatat aaaaataccg ctgaaattca
     4501 tatgcaatat aaagatgata tggactttaa cagttatata aacgctttgt atgaaatatc
     4561 tacacaagaa aatattaata tttctcaata tagttttact gctgttaacc aactaactat
     4621 tcttgctaca aaccctaacg ctaacaaaca ctggaaattt tctaaaaaaa atatattagc
     4681 aagaaacgat tctaaagtcc attatactaa taacaaaaat tctaagtacc aattaaaact
     4741 tccaaataat tttttaaata taaatattta tcctttttct catgtggaaa atattggatt
     4801 aagtgaaata ttatatgtac aaggaaactc aaacaaatta attcctgtac tgaaaaaata
     4861 tggaacacct actatttcca atatcaatca atcagatact tttcaaatta atactaatat
     4921 tgttcttgtt atctgctatc ttagtatatt tattgtaatt actacaatta tatttgcttt
     4981 ttcaaaaatg aaagaaatca ctctaaaaaa aatgttaggc tataactctt ttgatactat
     5041 aaaagattct attaaagagt taaacctctt attttgttct ttgattataa ctttcatttt
     5101 atctattttt ttgagcatat attacagtaa cgaaaatttt ttcctatcat ttcttctatg
     5161 tagtattttt cattttataa ttagtttttt atttatcata gttactctaa gtatctatca
     5221 tttatctagt ataaaaaatt atctaaaaaa ttcacgacca cttaagttaa atctttgtat
     5281 attaaatatc tgtctattct taagcatgat ccttctgtta atagcttcta caaaagtaat
     5341 aaatacccat aatgaagccg aaaataattc tcttaaatat tgggaaagaa ctactaattt
     5401 atacaaaaca aatattacta atcaattaaa tagaaacaac accgtagaag aaaataacta
     5461 cttgaaaaaa gctagtaaat ttgtttataa aatacagaag aattataaaa cttttattat
     5521 cgcgccatac aattacgcaa ctatccaaga gaataataaa gaatttttta ttggacaaaa
     5581 agtttatcca aattttgaag actatgttag tcaacctgct ggtgcaggaa tatgtgttga
     5641 tttaaactat ctaaaatatt acaatcctat ttcttttgaa gaatctactg acttaaattt
     5701 aataaactct gatccactaa ctacttacat tctagtacct aaaaaatata aagaatatgc
     5761 aaaaatgatt gaaaaaaatt atttagaaga catacagttt agacttgagg actctcctcc
     5821 tcaagctcct tataaaaatc ctaatttgaa aaatttaaaa ataaaactaa tatttgttaa
     5881 taataaccaa aagtatttta gttttaatac cttatatgga aaggcaaaag ataactatac
     5941 aataactgat cccatagtta gagttattaa tccagaaata acagaatcat tattttgggg
     6001 aaatatattg actagtgatg gtggattatt ttttgatcag aaacatactt caaaccaaaa
     6061 cttttttaat caaattaatc cgtatataaa agaatttaac ctagaaaata tcataaattt
     6121 ttcttattct gtttttcaag aaactggtga attattatct caaaaaaaag taaataaatt
     6181 aaatg
//
LOCUS       DAJSMK010000112         6168 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.120, whole genome shotgun sequence.
ACCESSION   DAJSMK010000112 DAJSMK010000000
VERSION     DAJSMK010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6168
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.120"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            25..1857
                     /gene="tet(M)"
                     /locus_tag="ON488_002379"
     CDS             25..1857
                     /gene="tet(M)"
                     /locus_tag="ON488_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCR3232521.1"
                     /translation="MTELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNII
                     DTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKID
                     QNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKY
                     MSGKSLEALELEQEESIRFQNCSLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKS
                     ELCGNVFKIEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKI
                     DKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLD
                     ALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYM
                     ERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVME
                     GIRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLE
                     PYLSFKIYAPQEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTF
                     FTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            1955..3328
                     /gene="tet(L)"
                     /locus_tag="ON488_002380"
     CDS             1955..3328
                     /gene="tet(L)"
                     /locus_tag="ON488_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCR3232522.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3892..5154
                     /locus_tag="ON488_002381"
     CDS             3892..5154
                     /locus_tag="ON488_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCR3232523.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            5399..>6168
                     /locus_tag="ON488_002382"
     CDS             5399..>6168
                     /locus_tag="ON488_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HCR3232524.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKN"
BASE COUNT         2132 a          883 c         1271 g         1882 t
ORIGIN      
        1 agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacaa aggtacaacg
       61 aggacggata atacgctttt agaacgtcag agaggaatta caattcagac aggaataacc
      121 tcttttcagt gggaaaatac gaaggtgaac atcatagaca cgccaggaca tatggatttc
      181 ttagcagaag tatatcgttc attatcagtt ttagatgggg caattctact gatttctgca
      241 aaagatggcg tacaagcaca aactcgtata ttatttcatg cacttaggaa aatggggatt
      301 cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc aacggtttat
      361 caggatatta aagagaaact ttctgccgaa attgtaatca aacagaaggt agaactgtat
      421 cctaatatgt gtgtgacgaa ctttaccgaa tctgaacaat gggatacggt aatagaggga
      481 aacgatgacc ttttagagaa atatatgtcc ggtaaatcat tagaagcatt ggaactcgaa
      541 caagaggaaa gcataagatt tcagaattgc tccttgtacc ctgtttatca tggaagcgca
      601 aaaagcaaca tagggattga gcagcttata gaagtgataa cgaataaatt ttattcatca
      661 acatacagaa agaagtctga actttgcgga aatgtcttca aaattgaata ttcggaagaa
      721 agacaacgtc ttgcatatgt acgcctttat ggcggaatcc tgcatttgcg ggattcggtt
      781 agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat aaatggtgaa
      841 ttatgtaaaa ttgataaggc ttattccggg gaaattgtta ttttgcaaaa tgagtttttg
      901 aagctaaata gtgttcttgg agatacaaag ctattgccac agagagagag aattgaaaat
      961 ccgctccctc tgctgcaaac aactgttgaa ccgagcaaac ctcaacaaag ggaaatgtta
     1021 cttgatgcac ttttagaaat ctccgacagt gacccgcttc tacaatatta tgtggattct
     1081 acgacacatg aaattatact ttctttctta gggaaagtac aaatggaagt gattagtgca
     1141 ctgttgcaag aaaagtatca tgtggagata gaactaaaag agcctacagt catttatatg
     1201 gagagaccgt taaaaaatgc agaatatacc attcacatcg aagtgccgcc aaatcctttc
     1261 tgggcttcca ttggtttatc tgtatcaccg cttccgttgg gaagtggaat gcagtatgag
     1321 agctcggttt ctcttggata cttaaatcaa tcatttcaaa atgcagttat ggaagggata
     1381 cgctatggtt gcgaacaagg attatatggt tggaatgtga cggattgtaa aatctgtttt
     1441 aagtatggct tatactatag ccctgttagt accccagcag attttcggat gcttgctcct
     1501 attgtattgg aacaagtctt aaaaaaagct ggaacagaat tgttagagcc atatcttagt
     1561 tttaaaattt atgcgccaca ggaatatctt tcacgagcat acaacgatgc tcctaaatat
     1621 tgtgcgaaca tcgtagacac tcaattgaaa aataatgagg tcattcttag tggagaaatc
     1681 cctgctcggt gtattcaaga atatcgtagt gatttaactt tctttacaaa tggacgtagt
     1741 gtttgtttaa cagagttaaa agggtaccat gttactaccg gtgaacctgt ttgccagccc
     1801 cgtcgtccaa atagtcggat agataaagta cgatatatgt tcaataaaat aacttagtgt
     1861 attttatgtt gttatataaa tatggtttct tgttaaataa gatgaaatat tttttaataa
     1921 agatttgaat taaagtgtaa aggaggaatt aattatgaag tgtaatgaat gtaacagggt
     1981 taaatacaac caaattttaa tttggctttg cgttttatct ttttttagcg tattaaatga
     2041 aatggttttg aacgtctcat tacctgatat tgcaaatgat tttaataaac cacctgcgag
     2101 tacaaactgg gtgaacacag cctttatgtt aaccttttcc attggaacag ctgtatatgg
     2161 aaagctatct gatcaattag gcatcaaaag gttactccta tttggaatta taataaattg
     2221 tttcgggtcg gtaattgggt ttgttggcca ttctttcttt tccttactta ttatggctcg
     2281 ttttattcaa ggggctggtg cagctgcatt tccagcactc gtaatggttg tagttgcgcg
     2341 ctatattcca aaggaaaata ggggtaaagc atttggtctt attggatcga tagtagccat
     2401 gggagaagga gtcggtccag cgattggtgg aatgatagcc cattatattc attggtccta
     2461 tcttctactc attcctatga taacaattat cactgttccg tttcttatga aattattaaa
     2521 gaaagaagta aggataaaag gtcattttga tatcaaagga attatactaa tgtctgtagg
     2581 cattgtattt tttatgttgt ttacaacatc atatagcatt tcttttctta tcgttagcgt
     2641 gctgtcattc ctgatatttg taaaacatat caggaaagta acagatcctt ttgttgatcc
     2701 cggattaggg aaaaatatac cttttatgat tggagttctt tgtgggggaa ttatatttgg
     2761 aacagtagca gggtttgtct ctatggttcc ttatatgatg aaagatgttc accagctaag
     2821 tactgccgaa atcggaagtg taattatttt ccctggaaca atgagtgtca ttattttcgg
     2881 ctacattggt gggatacttg ttgatagaag aggtccttta tacgtgttaa acatcggagt
     2941 tacatttctt tctgttagct ttttaactgc ttcctttctt ttagaaacaa catcatggtt
     3001 catgacaatt ataatcgtat ttgttttagg tgggctttcg ttcaccaaaa cagttatatc
     3061 aacaattgtt tcaagtagct tgaaacagca ggaagctggt gctggaatga gtttgcttaa
     3121 ctttaccagc tttttatcag agggaacagg tattgcaatt gtaggtggtt tattatccat
     3181 acccttactt gatcaaaggt tgttacctat ggaagttgat cagtcaactt atctgtatag
     3241 taatttgtta ttactttttt caggaatcat tgtcattagt tggctggtta ccttgaatgt
     3301 atataaacat tctcaaaggg atttctaaat cgttaaggga tcaactttgg gagagagttc
     3361 aaaattgatc ctttttttat aacaggaatt caaatctttt tgttccatta aagggcgcga
     3421 ttgctgaata aaagatacga gagacctctc ttgtatcttt tttattttga gtggttttgt
     3481 ccgttacact agaaaaccga aagacaataa aaattttatt cttgctgagt ctggctttcg
     3541 gtaagctaga caaaacggac aaaataaaaa ttggcaaggg tttaaaggtg gagatttttt
     3601 gagtgatctt ctcaaaaaat actacctgtc ccttgctgat ttttaaacga gcacgagagc
     3661 aaaacccccc tttgctgagg tggcagaggg caggtttttt tgtttctttt ttctcgtaaa
     3721 aaaaagaaag gtcttaaagg ttttatggtt ttggtcggca ctgccgacag cctcgcagag
     3781 cacacacttt atgaatataa agtatagtgt gttatacttt acttggaagt ggttgccgga
     3841 aagagcgaaa atgcctcaca tttgtgccac ctaaaaagga gcgatttaca tatgagttat
     3901 gcagtttgta gaatgcaaaa agtgaaatca gctggactaa aaggcatgca atttcataat
     3961 caaagagagc gaaaaagtag aacgaatgat gatattgacc atgagcgaac acgtgaaaat
     4021 tatgatttga aaaatgataa aaatattgat tacaacgaac gtgtcaaaga aattattgaa
     4081 tcacaaaaaa caggtacaag aaaaacgagg aaagatgctg ttcttgtaaa tgagttgcta
     4141 gtaacatctg accgagattt ttttgagcaa ctggatccag gagaacaaaa acgatttttt
     4201 gaggaaagtt ataaattatt ttccgaacga tatggcaagc aaaatattgc ttatgcaaca
     4261 gttcataatg atgagcaaac ccctcacatg catttaggtg ttgtgcctat gcgtgatgga
     4321 aaactgcaag gaaaaaatgt gtttaatcgt caagaactgt tatggctaca agataaattc
     4381 cccgagcata tgaaaaaaca gggttttgag ttgaagcgtg gtgaacgtgg ctctgaccgt
     4441 aaacatattg agacagctaa atttaaaaaa caaactttgg aaaaagagat tgattttcta
     4501 gaaaaaaatt tagcagttaa aaaagatgaa tggactgctt atagcgataa agttaaatca
     4561 gatttagaag taccagcgaa acgacacatg aaaagtgttg aagtgccaac gggtgaaaag
     4621 tccatgtttg gtttgggaaa agaaataatg aaaacagaaa agaaaccaac caaaaatgtt
     4681 gttatatcgg agcgtgatta taaaaactta gtgactgctg cgagagataa cgataggtta
     4741 aaacagcatg ttagaaatct catgagtact gatatggcga gagaatataa aaaattaagt
     4801 aaagaacatg ggcaagttaa agaaaaatat agtggtcttg tagagcgatt taatgaaaat
     4861 gtaaatgatt ataatgagtt gcttgaagaa aacaagtctt taaagtctaa aataagcgat
     4921 ttaaagcgtg atgtgagttt aatctatgaa agcactaagg aattccttaa ggaacgtaca
     4981 gacggcttaa aagcctttaa aaacgttttt aaggggtttg tagacaaggt aaaggataaa
     5041 acagcacaat tccaagaaaa acacgattta gaacctaaaa agaacgaatt tgaactaact
     5101 cataaccgag aggtaaaaaa agaacgaagt cgagatcagg gaatgagttt ataaaataaa
     5161 aaaagcacct gaaaaggtgt ctttttttga tggttttgaa cttgttcttt cttatcttga
     5221 tatatataga aataacgtca tttttatttt agttgctgaa aggtgcgttg aagtgttggt
     5281 atgtatgtgt tttaaagtat tgaaaaccct taaaattggt tgcacagaaa aaccccatct
     5341 gttaaagtta taagtgacca aacaaataac taaatagatg ggggtttctt ttaatattat
     5401 gtgtcctaat agtagcattt attcagatga aaaatcaagg gttttagtgg acaagacaaa
     5461 aagtggaaaa gtgagaccat ggagagaaaa gaaaatcgct aatgttgatt actttgaact
     5521 tctgcatatt cttgaattta aaaaggctga aagagtaaaa gattgtgctg aaatattaga
     5581 gtataaacaa aatcgtgaaa caggcgaaag aaagttgtat cgagtgtggt tttgtaaatc
     5641 caggctttgt ccaatgtgca actggaggag agcaatgaaa catggcattc agtcacaaaa
     5701 ggttgttgct gaagttatta aacaaaagcc aacagttcgt tggttgtttc tcacattaac
     5761 agttaaaaat gtttatgatg gcgaagaatt aaataagagt ttgtcagata tggctcaaag
     5821 atttcgccga atgatgcaat ataaaaaaat taataaaaat cttgttggtt ttatgcgtgc
     5881 aacggaagtg acaataaata ataaagataa ttcttataat cagcacatgc atgtattggt
     5941 atgtgtggaa ccaacttatt ttaagaatac agaaaactac gtgaatcaaa aacaatggat
     6001 tcaattttgg aaaaaggcaa tgaaattaga ctatgatcca aatgtaaaag ttcaaatgat
     6061 tcgaccgaaa aataaatata aatcggatat acaatcggca attgacgaaa ctgcaaaata
     6121 tcctgtaaag gatacggatt ttatgaccga tgatgaagaa aagaattt
//
LOCUS       DAJSMK010000113         6162 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.121, whole genome shotgun sequence.
ACCESSION   DAJSMK010000113 DAJSMK010000000
VERSION     DAJSMK010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.121"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(332..817)
                     /locus_tag="ON488_002383"
     CDS             complement(332..817)
                     /locus_tag="ON488_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232525.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(956..1201)
                     /locus_tag="ON488_002384"
     CDS             complement(956..1201)
                     /locus_tag="ON488_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HCR3232526.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            1394..2194
                     /locus_tag="ON488_002385"
     CDS             1394..2194
                     /locus_tag="ON488_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3232527.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            2213..4081
                     /locus_tag="ON488_002386"
     CDS             2213..4081
                     /locus_tag="ON488_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HCR3232528.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            4074..4565
                     /locus_tag="ON488_002387"
     CDS             4074..4565
                     /locus_tag="ON488_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HCR3232529.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            4553..5107
                     /gene="srlA"
                     /locus_tag="ON488_002388"
     CDS             4553..5107
                     /gene="srlA"
                     /locus_tag="ON488_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HCR3232530.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            5125..6120
                     /locus_tag="ON488_002389"
     CDS             5125..6120
                     /locus_tag="ON488_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HCR3232531.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2179 a          973 c         1233 g         1777 t
ORIGIN      
        1 atctttctaa tttgaaaaag ggatcattaa aataataaga agaaaatatg tcaaaaggta
       61 aaaaagtaaa ttcttctatc caaatataga aaaattgaat ctagaaaacc gcccgacaat
      121 aaatttcatt aactcagttg accgaaaatg aagtagatac caaaaattta tcaagagagc
      181 aagtagagaa gtgagtatat tcataagaga aatagctgta acgaattatt aggttaatgc
      241 aaatgcttat ttatactccg tataactttc tcagaaaaaa tgataccaat aatgacttgc
      301 tagtactgta aatccgtata atatcatcta atcaaaatgg tgttccattt gcatctgtca
      361 tcgtaatcga tccttcgggt gacactcgat aaaaaccaac gcttccagat cctccttggg
      421 aacggatttg tttgctggaa gctgtgaaca aataatctcg atcaattttt tgataaaagc
      481 taataacaat atcgtcactt tgtaattcgg aacggtgggc aataagaaat agaagtgctt
      541 tgtcagagtt ttctaatgga agagaaggta cagtgctttc ttgcatttca gatgttgaag
      601 aaatgctaaa cgactgaata cttgattggc tatgttgcga atctacatta ccagtagaag
      661 tattagtaat ggaagtagta gaagtacttt tagttgaacc aacctcagtt gttgaaatgg
      721 ctgctgaaga ttctttaaca gaattctttg ttttatatcc acaggcagaa aaaagtatta
      781 cagttcccaa caagcctgcg taaatccctt tatgcatgat agctcctcct aaaatagatt
      841 atctttattc agtatatcac ttaaacaaag aaaagcagat ggtttaaaat gaaaaaacct
      901 tcccaataaa gggaaggttc atgaagataa taactttttt aataattata gctttctaat
      961 atctttcatc aacttttcta gtaatcattg ggaaaaattt caagcagtag atcgcacaaa
     1021 tacctacgac gatataaatg atcttcgcaa aaatagttgt tgaaccacca gcaatcatag
     1081 ctactaaatc aagttcgaac aagcctacca acagccagtt caaccctccc acaatcaata
     1141 aagttaatgc aatagcatct aagttttcat tagaattctc ctttcttaaa tgataaaaca
     1201 attatatatc aaaaagagaa acattgctta tataacgctc aggaatttta gcaatctatg
     1261 caaaaagatg aaaatttttt ttgctcttcc attagtacac attttttagc tgaagctgta
     1321 aatttcatgt cttaattttt tttagtgagc ttttatactg gatttgtaag aaaaaagaag
     1381 gagaggatca catatgtcgg attggttgga tattgcagga aaagtagtaa ttgtaactgg
     1441 aggttcctca ggaattggaa gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt
     1501 agcgaatttt gatgtaactg aatgccgtat acagcatgaa aacctactat ctttaaaagt
     1561 cgatgtgtct tctaaaacgg acatagaaga agggatatat aaagtaatga aacatttcaa
     1621 gacgatcgat ggtctagtca ataatgcagg aataaatatt ccttctcttc taatagatag
     1681 aaatcatcca aaaagcaagt atgaattatc agaacaagtt tttgataaga tgatcgctgt
     1741 caatcaaaaa agtgtatatt tgatgagcca agcagttgga agaatcttgg tgcaaaaggg
     1801 atcaggagtg atcgtgaatc tttcttctga atcaggattg gaaggatcag aaggacagag
     1861 ctgttatgct gctacaaaag cagcgatgaa cagttttact cgttcttggg caaaagagtt
     1921 aggaaagagg aatgttcgtg tggtaggtgt tgcaccaggg atactggaag aaaccggttt
     1981 gagaacacaa gaatatgaag aagctctttc ttatacgaga ggtataagcg tcgaacagct
     2041 gagaaacggt tacagtcgaa caagtacgat ccctctagga aggagtggta agctgcaaga
     2101 agtggcggat ctagtctgct attatctttc agaaagatca agttatatca ctggagtcac
     2161 gactaatatt tcaggaggta aaacaagagg ataaaggata ggggggacgc acgtgacgct
     2221 agtaaacaga tggtaccaat tattgaaatt actagtcact cacaagaaag tttcaatcca
     2281 ggaagtgcaa aaagaaatca aaaccagtaa tcaaaccata aaaaaagata ttggggagtt
     2341 gaatgaagaa attgccggta ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga
     2401 aatttatgat tttgattttt ttgatgagat catgcaagga aaattgaaaa cagccagtga
     2461 tttcaattcg gcatccaaaa gaatcgctta tttactaaat aggctgatcg aaacagagga
     2521 tttcttacgt atggatgatt tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa
     2581 ggatctaaag acattaaaag agatgatcaa tgattttgat gtaaagatta caggcacacc
     2641 aaataaagga ctaagaataa taggagatga gctagaatta cgactacttt tattttattt
     2701 tgtttctccc tacttttcag agacgaaaac agaacagttt ctagaagaaa aacaagcaat
     2761 caaacatttt cagaagaaga cgaatgctag taaacaagaa atcacccttt taacgaaagt
     2821 tatcggtatt tctttgaata gaatctctag taactatctg ttgaagaagc ccatcaatcg
     2881 ttacagtggg tgttttgaat atatccaaga attcaatgaa ctgatcaatc agttggaaga
     2941 aatctatgaa ctaactttga gccaatatga aaaagatttt atcagttttc ctttgaacat
     3001 catcaacaca agtataacga tgataaggaa agctaactct gatttgcgct tatatttcga
     3061 ccccatgatg atgcgtattc gacgattaga tctcattgat ctggatgagt ccttcttata
     3121 tcaagagatg aaacagcacc tctctttatt gataaatcgg gtaatttttc gttatcgatt
     3181 gactgattta ttttatggtg agatagaaaa aaagtatcct ttttcttacc aaatcgctag
     3241 cgaatgcata caagcattag aagctatctt gcaacataag atctctaaag tagagatcag
     3301 ctacctaacg ttgtatttgg agttagcatt tcgatatcaa aaagagcatt tttcctctaa
     3361 aaaagtagcc attgttcata cgacaggaaa aggaacagca ttaatgatcc aaagacaaat
     3421 caaaaggata ttggggaggg atatacaaat aacacatgtt tcagaagaac aatatgaaaa
     3481 agtagatcta aacaaatatt tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga
     3541 agagacaccg gtgatccatt tgactaatct ttttgatgac tcttggttaa gggcacaatg
     3601 gcaaaaagca aaaaaaaagc gattagccgg gtttcattct actgtttttt tctatcaaat
     3661 atggaaagaa aaaaagacgt atcaagaata tttaaacaaa ttagtcgctc ctttgatcag
     3721 aggctattat gtggatgaag aatttgaaaa aaggatcttg aaaagagaat atcagcaaag
     3781 cacatttgtt aacaaagaat ttgcttttcc tcacacaacc aaccagctat ctcaacacat
     3841 tgttttatca gtagggctaa taactgatca aggtttagca gaaacaggag gaaatggagt
     3901 tattttttta tttgccatac ctgaagaaat gacggctgaa gttgagaatg aattatttga
     3961 gctatacgat atcctatttg aactcataaa aatgggaata gatgagttta ttgaattagc
     4021 accgacacaa gaatcatttt taaaactaat caaaagtaaa ggagagagac ttcatgaatg
     4081 atatgtatct attcatagtt ttcgcagctt cagcttatgt gctgcaagca gttatcagtt
     4141 ggaagcaact aaagcatttc aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag
     4201 cgattggtaa acgacctggg aaaatccgtt caggcacgat tgttatgcta gctatagacg
     4261 atcatgatca agttttagaa gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc
     4321 attcattacc tgtctatgcg ggtgaagata tccattacat cgatcgttac catccctcag
     4381 ttcgagcgga agatcgtttg acacaagcag ctttagaaaa tgccagagaa gtatacttac
     4441 gaatagaggc aggaaatgaa aaaagtgaac aaccttcatt gccttttatt gctatgctca
     4501 ataattttcg gatatggaaa agtacgatca aagaaaaaag gagtgacaaa cgatggatat
     4561 cataacaaaa tttgctgagg gatttatgag gctgttccaa acaggtgcag aaacattcat
     4621 aagctggatg acaggaatcg taccagttgt cttgatgctg atggttgcaa tgaatacgct
     4681 gattgctttt ttaggtgaag accgagtaac gaaagtagcc aaattatcag cgaaaaatcc
     4741 gcttactcgt taccttgtgt taccgttctt atctgctttt atgttgggaa atcctatgtc
     4801 atttacaatg gctcgtttcc ttccagaata ctacaaacca agctattatg ctgctcaagc
     4861 tcaattttgt catacgagca atggtgtatt cccccatatt aatcctggag aattgtttgt
     4921 atggatgggg attgctcaag ggatcgaaac cttagggcta aattcgatgg agctggctat
     4981 ccgatacttg cttgtgggac tgctgatgaa ctttattggt ggttggataa ctgattttac
     5041 tactggattt gtatgcagac agcaaggaat cgttcttagc aaaaaagtag agctttcagt
     5101 tgattagaga aaggagagtt ttaaatgtat ggtgatatta agatcgtaag aggaaacggc
     5161 gggtatggag gtcctttgat tattaggccg acaaaagata aacacaagtt catctatgtc
     5221 acaggtggag gtgagaggcc aatgatcgta gataaaatag aagaactgac aggtatggag
     5281 tctatcaatg ggttcaaaac atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac
     5341 tgtggaggga ctcttagatg tggaatttat cctaaaaaag ggataccaac catcaatatc
     5401 gttcccacag gaaaaagtgg cccattagca caatatatca ctgaagatat ttatgtttca
     5461 gcagtagggt tagaacaaat acagccacta atggaaactg atgataacaa agaaacagta
     5521 aatactgcat ctccagataa aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa
     5581 aaagcagagc agcaaaactg gatagcaaaa attggaatgg gcgcgggaaa agtagttgct
     5641 acattcaatc aatcagcaag agaagcagta gatacgatga tccggacagt gatccctttt
     5701 atggctttcg tttccctttt gattggtgtg atacaaggtt ctgggatcgg taatgtattt
     5761 gctaacatta tggcaccttt agcaggaaat gcagttggat taacaatcat tggctttatt
     5821 tgttcactgc catttttatc tcctttgctt ggtccagggg cagttattag ccaagtgatt
     5881 ggaacattga tcggtgtaga gattgggaaa ggaaatattc ctccccaatt agcattaccg
     5941 gcactatttg ctatcaatac tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg
     6001 gaagaagcaa aagctgagac agtagaagta ggtgtaccat cagttcttta ttcaagattt
     6061 cttaacggca tcccacgagt tatcattgct tgggtagcaa gttttggatt atatagctga
     6121 gtttagtcta atggtgataa gtcaagatga aatttaagat tt
//
LOCUS       DAJSMK010000114         6137 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.122, whole genome shotgun sequence.
ACCESSION   DAJSMK010000114 DAJSMK010000000
VERSION     DAJSMK010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6137
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.122"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            151..1452
                     /locus_tag="ON488_002390"
     CDS             151..1452
                     /locus_tag="ON488_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCR3232532.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
     gene            complement(1536..2483)
                     /locus_tag="ON488_002391"
     CDS             complement(1536..2483)
                     /locus_tag="ON488_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HCR3232533.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(2661..3464)
                     /locus_tag="ON488_002392"
     CDS             complement(2661..3464)
                     /locus_tag="ON488_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HCR3232534.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            3610..4524
                     /locus_tag="ON488_002393"
     CDS             3610..4524
                     /locus_tag="ON488_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HCR3232535.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            4572..5042
                     /locus_tag="ON488_002394"
     CDS             4572..5042
                     /locus_tag="ON488_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HCR3232536.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            5127..5735
                     /locus_tag="ON488_002395"
     CDS             5127..5735
                     /locus_tag="ON488_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HCR3232537.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            5869..6069
                     /locus_tag="ON488_002396"
     CDS             5869..6069
                     /locus_tag="ON488_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCR3232538.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         2013 a         1023 c         1185 g         1916 t
ORIGIN      
        1 ttcttcttca agaccaaata aaaaaggctc tataatttct aggactgata gaaaatcatt
       61 ctatcggtcc cttttgagca tgaaaaaaca aaacatacag aagctccgtt agaattgaat
      121 caccacaaca caatcaaagg agcgttctgt atgcctgatc ttcatcatat caaactacta
      181 cttggaatca aagataaaaa cattttcatc acaaatgtgg aatcgaagag cattaagaat
      241 atcaagagtc ttgttgtttc tgcgacgtta agtaaagaaa ttcgtcgctg tcctttgtgt
      301 aaacagatga atcatgaagg catgatcgtt aagaacggaa agaaaaaatc gctcattcaa
      361 cttaataaat gtgcgaacca actgacttat cttgctttag cgaaacaacg ctaccactgt
      421 cgtggctgcc acacctattt tacggcgaat acctacattg tcgatagaaa ctgctttatc
      481 gctaaacaag tgcgctataa aattttagaa gagctaactg aaaaacaagc aatgacgaca
      541 attgctaagc attgcggcgt ttcttggtcg accgtttctc ggacactcgc ttctctgatc
      601 cccatgacaa aagtaaaaag aaattggtta ccgcgttgtt tattaatgga tgaatttcgt
      661 tcactgaaaa atcaagtcgg tccctactcc ttttcttgta tggatggcga tactggaaaa
      721 ttactggata ttcttccttc acggaagaaa aaggctctcg tttcttattt tatgcaattt
      781 gaacgacgcg cacgattgaa ggtaaaggtc atcgtgacgg acatgaatgt ttcttatgcc
      841 tctctgataa aggaatgttt tccaaaggca aaactcgttg tggatcgttt tcacattgtc
      901 aaacatctca ttcgtaaatt tgaggatatt cgcgtacgaa tcatgaaaag ctttgatcga
      961 aacgatccaa cacaagccaa atattatcga caattaaagg cgttgtctcg gcttctgatc
     1021 aaacgacagg acaagcttgt ttatgacaaa tggaccaaat ggcgcaattt tggttgggcg
     1081 tatctcaccg aaagtgaagt ggtggatcgt ctgctttcga tctctgacga attacgaatc
     1141 gcctattttt actatcaaga aattcttcaa gcgtttcacg acaaagaggc ggacactttc
     1201 tttaaacttg taagaacgat gcccaattcc gttccaaaag aactgcattc tataaaaaaa
     1261 gcttttataa actatgaatc cggcattcgt ttagccctcg aattgcctta ttcaaatgcc
     1321 aaaatagaaa atctgcatac ccacatcaaa gcattgaaac gagtcgctta tggctttcga
     1381 agctttcgga aaatgaagac cagaattttc ttactaaata atctgattac ctatgaatca
     1441 aaaaacatct aaagtagaaa aggaattcta ccttagatgt tcttatctca ctctatcagt
     1501 cctatttgac aaagagccaa tattgttttc agctattaat atcctgcaga caattttact
     1561 tgattggttt gaagctcatg ggtggcaaag tagcttttca gattggttaa aaaaatagcc
     1621 attaatttct tttgaaaatc aggtgtcaaa cctgcaatgt gggaagtaat cagtacattg
     1681 tccattttcc aaagaggatg atcttgtgga agaggctctt cctcaaaaac gtctaatgct
     1741 gcaaaggaaa gttgctggtt atttaaagcc tgcaccagat cttgtgtctt aacagaagca
     1801 ccacggccaa cattgatgaa tacagatttt ggatcaaagt gttcaaacat atgctgatca
     1861 aagagcccag ttgtttcctc cgttagaggt aagatattga ctacgaaatc tacttcagga
     1921 agaacttcct ttagttgatt taaagaaaaa gtcttttcca ttccttctgc tggatgaccg
     1981 gatgtattga ttccatagca gttcatgtct aatgctttgc atttttttgc aatcattttt
     2041 ccaatatggc cagttccaat gattagtatt tttttccctt ggatagattg gtaatggacc
     2101 gatgaaccta accatttcat gtcactctgt gccttttgtg cttgaaaaag accacgagaa
     2161 tacccaagga tgattcctaa gacatgctcc gtaatcgatt cactgtggat gccactacca
     2221 tttgaaagta aaatatgttt ctttgaaaaa gtctcaaggg gtagctgatc aacaccagct
     2281 gagatagatt ggacccattt caaggtagaa gaggctaata gtttttcttg gtagtctgag
     2341 ttccagccca aactgatctc tacattttgt agatcctctg gttgtaattc tgttttaaag
     2401 atataaccag gcgctatagt atggatttct tcgataaatt catcacgaaa tggacgatct
     2461 gcataaatga ttctttctga catagttaat ttcccgcctt tctttactct aagtgtagcg
     2521 catacaagaa gaactttgaa gcgccttgct tgttttttga gaaagaaata tttttcaaat
     2581 aaaaaagggg ctgtgacaaa aaaatgtcac aacctctaaa agggtctatt gaagtagaaa
     2641 taacgagttg tctttatttc ttaattgatc gatatttttg cccatccttt gacagcttga
     2701 gcaaaaataa agattcctgc aaaagcaatg aaggcgctag tgtcaaaaga aggaagaaag
     2761 accatcaaga ttgttgcaat tatagtaggc aatgaaattg aatagatcaa tgtttttaaa
     2821 caatcaagaa aagtagcttt tgttagtcga aagcgtgcat agagaaaagc agcaatgttg
     2881 gtaaatagca aagtgatcag cagattcaga aaactaggat aaatagaaaa tataaatgtc
     2941 aggactttta tccaaagtgg tatagatgct tcacttaaaa aagaacggag ctgcttacct
     3001 gttaagtttt ttaaagattc attggtgtag ggaagttcta attggttatt gttcaacaaa
     3061 gcagaagtcg tgcctgtatt aggaagagct atgataagtt tgttttttaa catcccgaca
     3121 ctaacaaaat tccccatcaa atcagtagag atgtcctgtt ctgttcgttt tccctctgga
     3181 tcaaatgtga agataatgga gtttgtttgg taaatgaatc cttctttttc ttcggtttga
     3241 agctgcccgt tttggattgt aaaatcagga atgcgagtag caatcttttg cccatccaat
     3301 tgaatgttgt ttaagacttg aaaaacttga aaagagattg gcaaagccat aattatactc
     3361 aaaactaaaa gatagacaat ggctttccaa aatgggacat ttctcgcctc ctttaggtct
     3421 ttgaatcgta taaaggaact gataattaat tgttttgttg tcataagtac tcctcatcta
     3481 gtagtgtcat cacttgcaat tctagcgaag tatcaagtga aatacaagtg ctttaaggaa
     3541 acagctgaat gattggtgaa atatcaaaaa aatgttattc ttgtctaaag actatccaat
     3601 ataaataaaa tggaggaagg aatagtgcct acacagccac agagatcatc aaaaaaacta
     3661 tttggagtag tggttttgaa tgcggtgatc actttatcag aatttattgg agggattatg
     3721 tcagggagtt tgtctcttgt ttcagatgct ttccataacc ttagtgatac attggcaatt
     3781 attttttctt acggggcaca aaaaatggcc cgaaaagaag caaataaaaa acgtacgtat
     3841 ggctaccagc gtttagaaat attgagtgct ttcatcaact cattcatatt gatcatatta
     3901 tccttgtttt taaccgttga agcattcaag cggttcactt caccagaaaa gataaatagt
     3961 catttgatgc taacagtagc agttattgga ttgctcgcga atttgttctc agtattatta
     4021 ttacgacaag aagcagatga aagtttgaat ataaaatcta gttatttgca tttgttaagt
     4081 gatacactgt cttcggtaag tgtgattatc ggagcaattt tgatccgttt tttcgatatc
     4141 tactggatcg atccagttat tacactgatc atttcgatat atatattgat agaagcgata
     4201 atggtgatca aaaaagctgc cgctattttg atacaaagtg cacctgctat cgactatgaa
     4261 aaaatggaac aagaaattga agcaatcgat ggggtaaagg atgttcatca tgtccatatt
     4321 tggcagtata gcgaaaagat aattattttc gacggacata ttgattttga agatcagcta
     4381 ctaagcgaga ttgaaaagat atatcctcgt ataatttctt tattaaaatt aaaatatggt
     4441 attacacatg tgacgatcca agcagagaca aaggcaaagg atcaaaaaaa attaattttt
     4501 ttaaataaag atgaaagtta ttgaaatata gagtatgata aataagaatt tttaataagg
     4561 taggttggct catgaagcag tatcgacagt taaaaggata tttagaagca aaaggatatt
     4621 gggagatact agtctatctc ttttttggtg gtttggctac gattgtaaat tttgttagtt
     4681 ttgctctcgc acgccaatat tttgatttaa gtatggcctt atccaattct atttcgtggt
     4741 tttgttctgt attgtttgct tttgtaacga acaaactttg ggtattccat tcaaaatcac
     4801 cgaattttac acatgcactt attgaatgcg gtaagttctt cttctaccgt atcctttctt
     4861 acggattgga catgggggca atggtattgt tgatcaatgt tatgaacagc aatgagtatg
     4921 tggcgaaaat catcactcaa attattgtta tccttgcgaa ctatattttc agcaagttgt
     4981 ttatttttaa agaaactgag gtttttgaag aagaagtagg tcaaagtgaa aaagacgact
     5041 aggcataaca attgaagaat ttccttctct ttgttactct ttgtaatgta gacattatta
     5101 agaaaacatt gaggaggaat ttttttatga cttacacatt accagatcta ccttatgcat
     5161 atgacgcatt ggaaccttat attgacgaag aaacgatgca tctgcatcat gataagcatc
     5221 acaatactta tgtgacgaat ttaaattcag caattgagaa atacccagaa ttaggcgaaa
     5281 aaacaataga agaattatta tctgatatgg acgctattcc aacagatatc aagacagctg
     5341 tacgtaacaa tggtggcgga catgctaacc attcattttt ctgggaaatc atggcaccaa
     5401 atgctggtgg cgaacctaca ggagaaataa aagaagcgat taatgaagct tttggtgatt
     5461 tttcttcttt taaagaagaa ttcaaaaaag cagccgctgg acgatttggt tctggatggg
     5521 cttggcttgt aatggaaaat ggaaaattag ctattacctc tactgcaaat caagattctc
     5581 cattgatgga aggaaagaca ccaattctag gtttggacgt ttgggaacat gcttattatt
     5641 tgaaatataa aaatgtccga ccagattata ttgcagcatt ctggaatgtt attaattggg
     5701 atgaagtaaa caaacgtttc gaagcagcaa aataaccatt tcctccgtca tatcagtctt
     5761 aaaaataatt tggaaaataa aagagcgaaa gcttgctagc gttttctaaa ttgggtataa
     5821 tgttcttgca aggttacttg caagaacttt tttggaggat atacatttat ggaacacgga
     5881 acggttaaat ggttcaacaa tgaaaaagga tttgggttta ttacagtaga cggcggagat
     5941 gacgtatttg ttcatttctc agcaattcaa ggagacggct tcaagagcct agaagaaggt
     6001 caagaagtag aattcacgat tgttgaaggt gcacgcggac ctcaagctgc tgaagtgact
     6061 aaattataat aatttgttga ataaagacac gacttcttag agagtcgtgt ctttttgtct
     6121 atttatgaag tttttag
//
LOCUS       DAJSMK010000115         6073 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.123, whole genome shotgun sequence.
ACCESSION   DAJSMK010000115 DAJSMK010000000
VERSION     DAJSMK010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.123"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            86..979
                     /locus_tag="ON488_002397"
     CDS             86..979
                     /locus_tag="ON488_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HCR3232539.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            1113..1238
                     /locus_tag="ON488_002398"
     CDS             1113..1238
                     /locus_tag="ON488_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232540.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1372..2004)
                     /locus_tag="ON488_002399"
     CDS             complement(1372..2004)
                     /locus_tag="ON488_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232541.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(2152..2694)
                     /locus_tag="ON488_002400"
     CDS             complement(2152..2694)
                     /locus_tag="ON488_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HCR3232542.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            2829..3218
                     /locus_tag="ON488_002401"
     CDS             2829..3218
                     /locus_tag="ON488_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232543.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            3222..3986
                     /locus_tag="ON488_002402"
     CDS             3222..3986
                     /locus_tag="ON488_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCR3232544.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            4115..5062
                     /locus_tag="ON488_002403"
     CDS             4115..5062
                     /locus_tag="ON488_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HCR3232545.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            5192..5932
                     /locus_tag="ON488_002404"
     CDS             5192..5932
                     /locus_tag="ON488_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232546.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT         2124 a          989 c         1188 g         1772 t
ORIGIN      
        1 aacagtcaat tatgactctt gttcttcctc ctttttacgt aaaagccttt taagtaaaat
       61 aaaacggata gaaaagagaa catatatgaa ctattattca aaaaataagg aaaactttta
      121 tcaaaaactg accgatgatc cgcttttttc ttcattgacc gattatctat atgaacatcg
      181 agaacaagaa acgattctaa gagaattgaa aaaagaattt tcgcaaaata aattttccca
      241 ttttcttgat ttattgatcg atgcaggatt aatcaagagg gaagaacgaa gatatcattt
      301 gaactttcca atatttgatc ctaaagatta cttgcaacaa gccacttcgg ctgctgaaac
      361 catagctgaa caattgaaga gactctctgt tgatgaacaa aaattagcga tgggagaagt
      421 tatttgggcg tattgtttcg aagatgaacg gaaagaagcg tatttttatg gagtaagaaa
      481 cagccgagag acagaattgc tgaggacaac tgcaggaaat gagaagtacc gttttatcac
      541 actttcctct atagaacact tcccgcttac tttggctaat tacttttttg tacagaagaa
      601 tcagcttcct gtaacgaagg cattcaaaga attagccgaa cttattggag acgtaaatga
      661 atcgtacttt tttgatcaaa tagaagttat cgttgacagg atacgtaaga ataaatataa
      721 aaatcgccgg cctagtattt tccatcagtc tctacttgtg acgaatacta taaaggaaga
      781 agaatcattc acattagaat tacctattgt cgaaaaaaac aattttgaga ttgaattacc
      841 aacattggat ccttcattga caatggagga aatggccttt cttaaacgac aaatcttttc
      901 tgagctgagc aagaaattta taccgcatgc attttcttat atcaaagaat atggaacagt
      961 tttagtgagt aaaacctaag agagcagtaa gcaaaaatta tactgactct tgcaggagga
     1021 gcctttctct tcctttatgg ttaaaagaat tatttgagta ttttgcctat ctaccaccta
     1081 ttagattcac tacatggtct ggaaacaaag gaatgcaaaa aaatggtgag aaatgtggaa
     1141 tgacaaagga agtagtgata agaaaagtta gatttttaaa taatcaatat tatgattcag
     1201 tcaagtatgg cattttatgg gaagaactag ctgattagat taggaagtcc atttgataat
     1261 ccagaatcac taagaaacga atggcgagtc attaataatt tatccaatct tgggttattc
     1321 ttttagattg aagtgtttaa aactaaaaaa gcatttatga agtcgtaata gtcaggcttc
     1381 aaaatgcttt ttattttgtt tgttttttct ttgccacata aatacaccta gactgacgat
     1441 gaagagcata tccaacagat ttcctgcgac ttggatcgtc gaagggttgg tcagtggcat
     1501 taaagcaagg acaaaaaagg aaaacaagct gtaaataaaa caggtgacag gaactaatcg
     1561 aaagaagagc ggacatttca attggctaaa aatgagtgaa aaaataaaat aagtaaaaat
     1621 ggataaaatc acgactaaac cattcatgat aaagaagaaa agcgtattgt gattaaacga
     1681 ataaaaaaga attgctaaaa aagaaaacgt tttaaatgca atcaatacgc ttgaagcttc
     1741 gtttaacgta ccaggatgtc gatgaaaaaa ataggcaccg aaataaacag aaaacagtaa
     1801 gccgcaaaga gaagacaaaa tcaaaaaaaa cggattttct tcggcttctg tgatatcaga
     1861 atgatccaaa agcaaccagc ctaatgcact agaaggcgca tgtgaggtct taaggtatga
     1921 ataacataga aaaaataaga tcgtcaaagt tgcaaaaaaa gagcctaaat gtaaaaaatt
     1981 agtggttcta cgttgaattt ccataatatc tccaaattaa attgataagt atataaagta
     2041 taataacaaa ttgatgagta tatgtcgatg ttttttaatc aaaataataa ataaaaactg
     2101 tctaacattt aaaatttaat ttagatatta gacagttttt aagtttgtga gttattttcc
     2161 ttgtcgtttt ctcacttttt tagtccagaa accacctgaa atatattttg gctcataaga
     2221 aatgataaaa gcacgctctt cgatttcttt gatcaggcga tacagttcac gttcgctttt
     2281 tctaggagaa agtatttcga gaactagccg ctcaccttcc agccccattg cagaagtctg
     2341 tgtcacacca taaccgtgtt ctctcagtat acccggcaaa cttttatctt ctgcgctatt
     2401 tgctggcaaa atcgttgtga ccatgatgta tcctaatgcc aatttgtctt caatcaaaat
     2461 tccgacactg atacctactg cgtaacctaa cgcatagaca aataaattca gtggattatc
     2521 taaacgatct aaaacaaggg ataagccgac gatataaatc gtgatctcga ccatactgac
     2581 aagtggagca atcagtcgat agcctttcat tgtcaacatg aaacgtaacg tgttcagagt
     2641 gatataagca aaattaatga ggaagatcat ccccaacatt tttggatcaa tcatttgtaa
     2701 aactcctttc atttatataa caacaatatc aaaaaaaatc gtaagtgaag aaaaattgaa
     2761 actttataca tacaaaaaaa tgataaaatg attataatag aattataaag ataggttagg
     2821 tgattaaaat gaaaacggtc aatcgtgtgt tttgtgccag ccacgtgcta agtctccttc
     2881 tcagtatata cttaggtgtc tattcgattc aacagccaat tgaggtagag aacattgttt
     2941 ttcagatgtc gctgacagat ggtttaattt taagcgtttt tttctttttg atactgttta
     3001 ttggtaatat tttcggtagc gttgccagtt ttttgaattt ttctatttat ccactccttt
     3061 cgctagcatt aggagtggtg ggactttgtt ctctgtgctt atttcccgag ccattcagtc
     3121 ctgcatttat attatttggt acactgaacc tgttccagac aactgttgga gcatggttgc
     3181 tatggcgatc aggaaattta atgaaaatag gtgagtaaca attgaatcca attatattga
     3241 aacgttctgt ccatcatatt ccagtgttag aagttgttct gaaagaatta agagaggaac
     3301 gtattcccgt tgtcatctat tatcacggat ggcagacaag taaggagtta gttttgacgc
     3361 aaggaagaaa aattgcgcag cagggcattc gtgtgatcct gccagatgcg atgaatcatg
     3421 gggagcgcaa acagccggtt tcttctattc catcctatac attttgggat agtatctacg
     3481 gaaatctgtt tgaatttgac acacttatca agcatttaga aaaaagaggt cttctacatg
     3541 atcagcttgc agttggcggg gtttcgatgg ggggaatgac aacatgcgcc ttgttggcta
     3601 aacatcctca tatagtagcg ggcgtgtgtt tgatgggttc ccctgcacct ttggaatatg
     3661 gaaaagaaat cgtaaggcgc gcatcggaat ataattatgt cgtaccaaaa gactattttg
     3721 atttgatttc atgggttaag agctatgatt tgtcattgca gccggaaaag ttagctggac
     3781 gtcctctgtt cttttggcat ggacaagctg acgaaaaaat cccttatata caaacggaac
     3841 gatttgtaga aaaaaatcgg cataagtctt acggaaaaga aattgttttt cgttcctcaa
     3901 aaacacagcg acatatggta caaataccac taatggaaga agcttccact tttttagcaa
     3961 aaaatttgat aaaaaagtat aaataattga aacggaaaat cactcatgac gatagaggat
     4021 tttccgtttt ttattttggg ctataataaa ctctgttagg aaaatttggt ataattgata
     4081 gtaagaatga caacatgtta gaaaggaaga gagcatgccc actttagcag atgttgcaaa
     4141 acgtgccaat gtttcaaaaa tgacggtctc tcgagtcatc aatcatccgg aacaggtgac
     4201 tgacgaattg aaagagttag ttttctcagc aatggctgaa ctggattacc gtccaaatat
     4261 tgctgcaaaa gcacttgtca cgaatcggtc gcagatcatc aaattattta tactggaaga
     4321 aatcgacaca actgagccct attacatgaa tttgctgatg ggaatcgcta aacggatcgg
     4381 taaagcgcat tattctctcc aattagttac aaatgatgcc ttcgacgtcg gttcttgtga
     4441 tggatacatc atcacaggtg tcagaaaaaa agacttcgat tggatcgacc gtttggaaaa
     4501 accagttgtc ttgtttgggg aaaattctga aggatatgat tatgtagaca gcgataatga
     4561 atatggtaca gcaaaagcaa cgcaatatgc cttagaaaga gattatcaaa cgattattta
     4621 tatcggtatc gaagtggacg agccttttga aatttcaagg gaaactggtt atttatctgt
     4681 gatgaaggaa gttgatcttc ctagtaaaat cttgcggttt ccaaatcatt cgacagaagt
     4741 agaaagatat atgacagaaa actgggcaga ttttacagat aaaacttgtt ttgtatgtag
     4801 ttcagatcgg ctagcactag gagcagtaag agggattata aatgctggag gacacttgcc
     4861 cgaagaattt ggtgtgattg gatttgatgg ggtattttta gaccaaatca gttcacctaa
     4921 attgacaacg atcaagcaag atattatacg tatgggtgaa gtatgtggag aaatgttgtt
     4981 aaaaaaaata gaagaaaaag gggcgagtca aggttatcgt cgtttttttc ctgaactagt
     5041 tatcagagag acaacgaatt aagtcttatt actatatata tatttatgaa attcatcgct
     5101 attttcttaa aataatcagc gcattgctac tgaaaacaat gaatctgtgc tattattgag
     5161 aaaagttcca tttttgagaa ggatggtttg aatgaaagaa atcagacgaa aacatttccg
     5221 ttttcctgcg tacgatgatg agttaggcgt aaaattaacc aacgacaaga agcgagtatt
     5281 atttgacgga caagaagatc ttttgactga acagaatcag tccccgtttg aacagatgaa
     5341 agaatttcat ttcacgaaca cgaacaccga gaaaatccgt cgcaagcgtc gtgcaacaaa
     5401 tggattgaag tcagctccgc gtaaggaaaa tttggaaaag cataaaggaa aattaccgga
     5461 ttataccggc cattaccaat cagaaatcac atcgacagga cgaaaaaaac tttttggtga
     5521 ttcctctcgt tctgtcagac aaagtgaaac aaggacagag tccaagcata ctacacgaaa
     5581 cgcatctgtt gacacgaagg tgcgggagcg ttcttatttt gttcctaaat atgtacccgc
     5641 atcgattatc ccagacccta gagaaagcaa aatttctgag gatcatttaa tcgaatcgat
     5701 gaaaaaaacg gatgactctt atctgttgtt cgatacagaa ccgacgccgt atcaagaaaa
     5761 aagaaatggt gagccgtctg tacgaacatt caatcgaaca aaaacgttag aggaaacaaa
     5821 gcagtcagaa gaaaaaaaat cgaaaaaaag ccatggtatc ttagaacgct cattacaagg
     5881 attgatcgat gatcaaggaa actctttggg agaaaatagc tattttaaat aagtgatata
     5941 caaatttata ttcggctaca gttggaaagg aaacgctgcg gcgtttcctt attttatact
     6001 ctatccgaaa gtttatatcg tatcctcaaa tttttttgag tttaagcgaa ttttttctcc
     6061 caataagtaa gaa
//
LOCUS       DAJSMK010000116         6024 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.124, whole genome shotgun sequence.
ACCESSION   DAJSMK010000116 DAJSMK010000000
VERSION     DAJSMK010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6024
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.124"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            24..542
                     /locus_tag="ON488_002405"
     CDS             24..542
                     /locus_tag="ON488_002405"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HCR3232547.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            670..1353
                     /locus_tag="ON488_002406"
     CDS             670..1353
                     /locus_tag="ON488_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HCR3232548.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1662..1735
                     /locus_tag="ON488_002407"
     tRNA            1662..1735
                     /locus_tag="ON488_002407"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1696..1698,aa:Arg,seq:tct)
     gene            1894..2253
                     /locus_tag="ON488_002408"
     CDS             1894..2253
                     /locus_tag="ON488_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HCR3232549.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2376..4007
                     /locus_tag="ON488_002409"
     CDS             2376..4007
                     /locus_tag="ON488_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HCR3232550.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4069..4710)
                     /locus_tag="ON488_002410"
     CDS             complement(4069..4710)
                     /locus_tag="ON488_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HCR3232551.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    4896..4972
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            4992..5300
                     /gene="rplU"
                     /locus_tag="ON488_002411"
     CDS             4992..5300
                     /gene="rplU"
                     /locus_tag="ON488_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HCR3232552.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5327..5671
                     /locus_tag="ON488_002412"
     CDS             5327..5671
                     /locus_tag="ON488_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HCR3232553.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5684..5977
                     /gene="rpmA"
                     /locus_tag="ON488_002413"
     CDS             5684..5977
                     /gene="rpmA"
                     /locus_tag="ON488_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HCR3232554.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1876 a         1014 c         1286 g         1848 t
ORIGIN      
        1 aataaagaaa gaagttgaaa acgatacctg attacaaaaa aataactttt ataagttcta
       61 taacgttgat tatattttta attcttattc ttctcgtcgt cttggttccc cgaatttttg
      121 gtttgactcc ttatattatt gaggacaaag aaatgagtcc atattatgca caaggaaatc
      181 tgatatatgt acgaccgaaa aatacaaatg agattttagt cggagatatt attacatatt
      241 atgaaaattc aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa aacaaccacg
      301 aagattttta tacaaaagct gatacaaaga cttatattga gcctggagta gtaaaaaaga
      361 gaaatattat cggtagtccc atctttcaga ttccatatat tggactagtc ctttcaaaaa
      421 cggcatttgc atggattcag gggttattct ttacgattgc tttttgccta acaggaatca
      481 cagcatggaa tacctttgta gagttgaaaa agaagcggag acgaacacag aaatttttgt
      541 aagaatgtta aaaacataaa tgtattccag agatccaacg actcttctga acatgaaaca
      601 cgagaaaaca ctcatgcagc ttgtagattt agtcagttgt tcgtataatg tgtgaagagg
      661 aggagtagta tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga actattggat
      721 tttatgcgta cccagcaaaa aaaattaccg ggtgagctag gcaaactgga agaagaagct
      781 catgtagcag aagtaccagt tattccccat gaaacagttg tatttttgaa atttttactt
      841 ggacagcttc agcctgaacg aatcttggag atcggagcag ctatcggttt ttcatcaagt
      901 gtcatggcca cgacaatcgg agaaaacgct catgttacga caattgatcg tttcgatgtc
      961 atgatcgaga aagctaaaaa aaactatgaa cgtctaggac tgacagataa agtgactttg
     1021 cttgaaggtc aagcagcaga tatcttgccg gagttgtctg gtccgtatga ctttattttt
     1081 atggatagtg caaaatcaaa atatattgaa tttttacctg aatgcttacg tttgttaaga
     1141 aaaggtggcg ttttgatggt agatgacatc ttccaaggag gaacgatctt gctcccagat
     1201 gaagagattc cccgtggcaa acgagctatc catcgtaaat taaatgaatt tcttcgtgtt
     1261 gtgatggatc atcccgattt gacatcgaca atcttgccat taggtgatgg tgtgatctta
     1321 atgacaaagg aatcagaaac aatcgagttg tgatacatga ttatggcagc ctgtagataa
     1381 tcgattgaat cgagggctca attcgaactt gatgtaaaag tttctatatt tgtaagtcaa
     1441 ttaaaggata caggaaatct aaataaacag gagtagcatg aagtcaatgt agctcctgtt
     1501 ttcaattgat aaccttagaa cagctgaagg agaatgtctc gttttaaaag attgatttag
     1561 tagttgggcc aaaataattc attatttgct aattaaataa ctatttcgta ttgacagaag
     1621 caatttaatt atctataatt attgatgttc cgctgattct tgtcatagta gctcagctgg
     1681 atagagcatc cgccttctaa gcggacggtc gggggttcga atccctcctg tgacgctaaa
     1741 aaaccgttag aaactgaggt ttctaacggt ttttctttgt tttttgtgcc aatattgttt
     1801 gttttcaaag gcaaataaaa taaaaaaaca tccttatcga gtacaattat aaggagcaaa
     1861 aaaataaaac tcatcagaaa agaggaagaa gatatgacga tactatctag aattttagtg
     1921 actctagttg caattgaatt tttttatatc atgtatatcg aaacggtgag aactgattct
     1981 gacacgacaa gtagggtttt taaaatgagt aaagaagagt taagcagaaa atctgttcaa
     2041 acattgttta agaaccaagg agtgtacaat ggactattag gagtgggact actttatgga
     2101 gcttatcttt cttccgcatc taaagaaatc acaagtatgc tattaatatc tatttttttt
     2161 gttgcattat atggcagttt gactagcgat cgttggattt tactcaaaca aggtgggcta
     2221 gctctgttgg cattgctttc tattttctta taaatataga aaaaataaga atttatctaa
     2281 caggaaactt tgtgaaaaat attactttat ctcatgaaat atgatattct aatgaatggt
     2341 attttagaaa atttcatgaa aaaggagtta gataggtgtt caaaaattat gtttcctcac
     2401 taaaaaaaga attttcaggt tatgatcttt caagatttca gaaagatctt ttggctggga
     2461 tcacagtagc tgctgtagca ttgcctttag ccttggcttt tggggtatca agcggagctg
     2521 atgcggccgc aggtttgatt acggctatca ttgccggtat cgttattggc ggtttatcag
     2581 gcggttttta tcaaatatca ggtccgacag gtgcgatggc agctatcttg atgtctattg
     2641 cggcaacaaa gggaatgcaa ggtgtattgc ttgctacttt tttagcgggt ctatttttac
     2701 ttgcagcagg acttttccga ttaggaacac tgacttcttt tatcccagca cccgtaatta
     2761 cggggtttac ttcaggtatt gctatcatta ttgcattagg tcagatcgat aatttatttg
     2821 gtgttcactc ggaaggtaca aacgttattg aaaaactaag tagttatcaa acgataggat
     2881 ttccgataaa cacagcctct ttgatcatgg gagggctagt cattttaggg atgtttatct
     2941 atccaaaaaa atgggcgaaa cgaatgccta gttcgctgct ggctatcatt ttggcaacag
     3001 cagttatgct attgttccat ttaccagtag caactgtggg taagattcca caaacattga
     3061 tcagtagtaa tcgtttgaat atgggagatt ttagcttttc tgccttgcaa caagtggcag
     3121 ttccagctat tagcattgct ttattaggaa tgattgaaag cttgctatgt ggtgcttcgg
     3181 ctggccgaat ggcaaataag cccttagata gcaatcaaga attaatggcg caaggaattg
     3241 gaaatctgtt gcttcctttc tttggcggga ttcctgctac tgcggccatc gcccgtacaa
     3301 gcgtggccat caaatctggt gcacaaacta gattagctgg tatgatacat gcagttgtct
     3361 tactgctctc catgcttgtt tttgcgccag tgatgtcaca gattccaatg ccagcacttg
     3421 caggtgtttt gattgtgacg gcttggcgta tgaatgaatg ggaaacgatc aaggagctat
     3481 ttactaataa atattggtca gcagttctat tgtttatcct tacgatgatt tgtacagtta
     3541 tctttgattt aagtattgct atcgtgatcg gggtgatcgg cggctgtgta ttttttgttg
     3601 tcaaaagcgc tgctatcacg atttcattag aaacgatcga ttggcaaaga atggggctgc
     3661 cagaaacgga aaagctgaat aactggacag tagtgtatat tagtggtcca ctgtttttta
     3721 tgtcttcaga aaaactcaaa aataaattgg aagaactaaa tcatcacgat ggtgtcattt
     3781 tctccatgcg aggcgtacca agtattgatt tgacggcacg tgcagttttt gatgaatttc
     3841 aagaaaaagc agagcaaaga ggacaaacga ttatctatac ttccttgcag ccagaagtag
     3901 aaaaacaact ttctcacttg tgggaacata cattcacgca tcaacatcaa acagttgctc
     3961 atgcgttgac agctttacat gcgaaatata ctgcaattag ccattaaaac aatgaaaaag
     4021 aacagacaag actgtaaact gaagatttta tggtcttgtc tgttcttttt aatattgctg
     4081 taaaagtgaa gctagtactt gccagtcttg atggataaca ggtacaaggg agcgattgta
     4141 gaaaatagct gctggatgaa aaagtggaag aattcgatag tttttttctg accattcgta
     4201 ggcatccttt tgttctgtta attgtaagac aggccctgta tagagttgac catgattttt
     4261 ggtaaccgta tattctttgc caagtaaacg ttgaagacca atgtttccaa gtgtcgcaat
     4321 taattttggc tggaccttca tcagttcgta atccaatatt ggtgcatgcg caaatacttc
     4381 ggaacgagta ggtgtccgat ttggataaac agtttctgac tgttgtgtcc gtttattgat
     4441 ccgatgagtc acgcgatacg ggcggctcct tacagcactg gtgatataca cctcttctcg
     4501 tgttaagcca gttgaagaaa gtgcctgcat caattctttt ccagcttgac cgctaaaagg
     4561 aacatgcgta tcaatctctg ttttccctgg ggcttctccc acgagcatca gtttaggatg
     4621 aagaggtcct tgcccagcga taaatccttc tacaggacgg ccgttcattc ttaaagaagc
     4681 ttcttgtatc agttcttttg ggtattccat ttatgctcct cctttttctt ttattataag
     4741 aataaaagaa acacaatgcg actattttat ttggtagaac tgtgaggata gaaaagcaga
     4801 agtattgctt gaatttttgt tttacttttt gattttaaat ttagttgact aacggttgct
     4861 gttctggtaa gctagtactg ttgtaattgt ggactccaca gctacaaccg ctcagaacaa
     4921 gtaataagca cagcatatgc tgtcacttcg gatggcgagt ctaagtatat cagaaggagg
     4981 tgctttatag catgtacgca attattaaaa ctggtggtaa acaagtaaaa gttgaagtgg
     5041 gacaagcaat ctatgttgaa aaacttgacg ttgaagcagg agaaaaagtt gtttttgacg
     5101 aagttatctt agtaggcgga gaatctacaa aagtaggcgc tccaactgtt gcaggtgcaa
     5161 ctgttgaagg tactgttgaa aaacacggca aacaaaagaa agtcgttact ttcaaataca
     5221 aacctaaaaa acattcacac cgtaaacaag gtcatcgtca accatataca aaagtggtta
     5281 tcgacgcgat caacgcttaa tagcgtttga gaaagaaggc ctatatatga tcaaaggaac
     5341 atttaagcga aatgacgcag gtcagatcgt ttcattcact ttgaccgggc atgctgatgc
     5401 tggtccttat ggaagtgata tcgtttgtgc gggtgtttct gcgttagcga tcagcactgt
     5461 caacgggatt gcctcattag ccggttttga gccgattgtt gaaatgaatg aagaagaagg
     5521 cggttatctt tataccgaag tcacttcagg aatgacacaa gaacaaaaca atattgctga
     5581 gattctatta gaaaatcttt tattaggatt acaatcgata gaagctgaaa actcagaata
     5641 tatccaaatt aaaacaatta atgataaata ggaggtgcag accatgttgt tatctatgaa
     5701 tctacaatta tttgcccaca aaaaaggtgg cggttctaca tctaacggcc gtgactcaga
     5761 atcaaaacgt ctaggtgcta aacgtgctga tggacaaaca gttacaggtg gatcaattct
     5821 ttaccgtcaa cgcggtacaa aaatctatcc aggtgtaaac gtgggtatcg gtggagacga
     5881 cactttattt gcaaaagttg atggcgtagt acgtttcgaa cgtaaaggcc gtaacaaaaa
     5941 acaagtgtct gtttatccag tagctcaaga agcttaattg aatcttatga ttaaagaggt
     6001 tgtgacaaga cttttgtcac agcc
//
LOCUS       DAJSMK010000117         5689 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.125, whole genome shotgun sequence.
ACCESSION   DAJSMK010000117 DAJSMK010000000
VERSION     DAJSMK010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.125"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(488..1297)
                     /locus_tag="ON488_002414"
     CDS             complement(488..1297)
                     /locus_tag="ON488_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HCR3232555.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="ON488_002415"
     CDS             complement(1297..2043)
                     /locus_tag="ON488_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HCR3232556.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="ON488_002416"
     CDS             complement(2061..2528)
                     /locus_tag="ON488_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HCR3232557.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="ON488_002417"
     CDS             complement(2528..2938)
                     /locus_tag="ON488_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HCR3232558.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="ON488_002418"
     CDS             complement(2949..3962)
                     /locus_tag="ON488_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR3232559.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="ON488_002419"
     CDS             4179..4913
                     /locus_tag="ON488_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3232560.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="ON488_002420"
     CDS             4897..5607
                     /locus_tag="ON488_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3232561.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAJSMK010000118         5674 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.126, whole genome shotgun sequence.
ACCESSION   DAJSMK010000118 DAJSMK010000000
VERSION     DAJSMK010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.126"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(284..447)
                     /locus_tag="ON488_002421"
                     /pseudo
     CDS             complement(284..447)
                     /locus_tag="ON488_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390190.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
     gene            complement(800..1489)
                     /locus_tag="ON488_002422"
     CDS             complement(800..1489)
                     /locus_tag="ON488_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HCR3232562.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFSHTRVGKNGKTFKMHKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYIGHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(1552..2316)
                     /locus_tag="ON488_002423"
     CDS             complement(1552..2316)
                     /locus_tag="ON488_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HCR3232563.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIVKDFG
                     KEKVVQMKQVAKDLINGDEISYPIYEEVKKKKFGLF"
     gene            complement(2344..3042)
                     /locus_tag="ON488_002424"
     CDS             complement(2344..3042)
                     /locus_tag="ON488_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HCR3232564.1"
                     /translation="MARTQKQKAAQTHVVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTIAANIAVVFAKSGQRVLLVDADLRKPVVYETFQLNNAS
                     GLSTALSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYRN"
     gene            complement(3054..3833)
                     /locus_tag="ON488_002425"
     CDS             complement(3054..3833)
                     /locus_tag="ON488_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HCR3232565.1"
                     /translation="MEETISLKEIFGTLRKHLATIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSENSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGSAPARPKATNDKTAPSRRSRSRV"
     gene            complement(3849..4793)
                     /locus_tag="ON488_002426"
     CDS             complement(3849..4793)
                     /locus_tag="ON488_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HCR3232566.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(4839..5618)
                     /locus_tag="ON488_002427"
     CDS             complement(4839..5618)
                     /locus_tag="ON488_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232567.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKERVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISVAYATKAQTVAQQMGYSNINY"
BASE COUNT         1508 a         1178 c          954 g         2034 t
ORIGIN      
        1 aaaaaaattg tcttagtttc ataatattta agatagtggt acatacttta taacaacgta
       61 cttttccaaa tattattttc cgttatgaac atccaatata ttacaaagtt taaaagttta
      121 gatgaactat aatcttcatt tctgcacagt ggataataaa ttcttataga taaaaaatag
      181 cctcttctaa agtcacaaat accttactcc cacattttaa gtaaacactc tgcagcattc
      241 tctttgttat aaaatgatag atattcctca attttatctc ttattatgtt attatcagtt
      301 gataccattc cattaatgtt tcagaataat tacaatattt tgggaccgga taactccctt
      361 ttgctcgtaa ccactcatat ccgttaggat tcactaaaag tttaccgttt atttttcgat
      421 tctttttttg aaccgtccca tgaacatacc gattcaacaa gctaaattat aaaaattggt
      481 gtgctgtcat tattttttgg aaaatttatt aatggctatc aatatacttt tgtatcatac
      541 taaatagctc gtcagttcct atatcggata taccaatatt aaagcattta gatcattata
      601 tttaagagtg gtatcatccc aaaatttcga atattttctt ttatataaga ataatgatac
      661 tgaattgccc cattcacctt tcttttttta gattttctac aagtgattca aaccctccat
      721 aattacagtt attacttttg aaacgataat atgaacatgt gtaatctttt ttattaacaa
      781 tccatcattc tatccctaac taatatgctc cattgggctt gacaataaca taaaacgttt
      841 tcaaaatcaa cctcaagtcg tacattaaac ttcgatgacc gatatactct aaatccaact
      901 caaccatttt atggaaacta acattatttc tatcactaac ttgccacaaa cctgaacaac
      961 caggttttac atacaagcgt tgaagatcat atctcgtgta ctcagctact tccctctcca
     1021 aaggtggccg tggaccaatt agactcatat cgccttttaa aacattccat agctgtggca
     1081 attcatcaat gcttttggca cggataattt tacctatttt agtgacacgc ggatcttctt
     1141 tcatcttgaa cattgcacct tctatttcat tttgatcaag taattcttcc aatttttctt
     1201 cagcatctaa acacatcgaa cggaatttat gcattttgaa tgtttttcca tttttaccaa
     1261 cacgtgtatg gctaaaaaat attggacttc ctggctcttc ttttctgatt cgataagcta
     1321 catagaacat caaaggagaa gctaaaatca aaccaataat gcttcctaca atatcaatca
     1381 ttcttttaaa aaataaatag atatatcgtt tttcaacttt ttctttatcc aaccaaactt
     1441 gattaggatg tacttcacta atacgagata ataaatcttc actttccata ctttcagtcc
     1501 ctttcactat cttcactctc tcctcatttg tttttatcta cgaataaaga actaaaataa
     1561 accaaacttc ttctttttta cctcttcata gattggataa ctgatctcat ccccgttgat
     1621 cagatccttt gcgacttgtt tcatctgtac tactttttcc ttaccaaagt ccttgacaat
     1681 ctgctcatag cactctttta agtaaaaggt gcgcttagag accccgtgtg catcagaagc
     1741 agccatctgc acgagattat gtttgaccat tgttttggct gttttctgga tgtctttgcc
     1801 aaatacacca acataacttg gcgcagtaat ttgggccaaa catcccatat ctaggaacgg
     1861 aagcaaatga tttgggtctt ctcgaaaatg cgcgttgcgt tctggatgga cgatcactgg
     1921 tgtctttcct agttctaaca actcaaaaaa aagccattct gcatataacg gcacttccag
     1981 tgtcggaaat tcgatcagaa gatatgtatc atctaaatct gtaaataaaa tttcatctcg
     2041 gtggatgtct tcgatgagcg ttccggtaat acgtacttct tgtccttcca ataacgtcaa
     2101 aggcaactgt cttttctcta attcggcttg taacgaagcg actagagaaa tgacttgtga
     2161 tttttcattg ctgtattttc cattattgtg gtgtggtgtg cataaaatat gcgtgatgcc
     2221 ttgctgaatc gctttttcag ccattgcaat acttgcttct aagttttctg ccccgtcatc
     2281 gattcctggt aggatatggc aatgtagatc gatcatttct cttgtctcct ctcttcttat
     2341 tccttaattt ctgtagtaat aaccagcatc tttgctatgt tctgctccgt tgtatacaac
     2401 acctaagact cgtgcttgta ccatctctag cagttctttt gctttagtca aggattcttt
     2461 acgtgatgta ttttcacgta cgaccaataa agtgccatcc gtttttgaag acatgatctg
     2521 tgcatctgtt acggctacta ctggtggcat gtcgaagatc actacatcaa atagttgtct
     2581 tgcttctgct aaaatctgat ccattcttgg cgagcttaat aactctgatg gatttggtgg
     2641 tttaggtcca cttggcagaa tcgacaaatt ctcgactggt gttcgttgga tctcatctgc
     2701 tacacttcct gatgaactaa gtgctgtact taatccactg gcattgttca gctggaatgt
     2761 ctcatagacg acgggtttac gtaaatctgc atcgactagt agaactcgtt gaccggattt
     2821 agcaaaaacg actgcaatgt ttgctgcaat ggtggatttt ccttctccag gacctgatga
     2881 agtcacgaca atcgttttga tttgctgacc agctgcggag gcaaactgga tattcgtccg
     2941 gatcgtacga tattgttcgg cgattggtga agatgggttt gttaatgtga tcaaactgac
     3001 tacatgagtt tgtgctgctt tttgtttctg tgttcgtgcc atttttcttc ctcctagact
     3061 cttgagcggc ttctgcgtga tggagctgtt ttatcgtttg tagcttttgg tcgtgcagga
     3121 gctgatcctt ttttacggat accagcgttc aattctttcg ctgacatttc tggaactgtt
     3181 cctaagattg ggaatcctaa tgtatccgtc acatattttt catctttcac tgtccgatca
     3241 agtaattcga ataagaatgc caaacctacg cctaccatca ttcctaatac taagccaatc
     3301 actagattca atttattatt tggcgaaaca ggtgtcgtat tggcaactgc acctgagatg
     3361 atcgagattt tatcgacatt catcacgtct tttgcgttct cttggaaaac ttgtgaagtt
     3421 gtattagcga tctgttgagc agtcactgca ttcgtgctta ttgcctggat cgagaacatt
     3481 tgtgagtttt ctgactgatt gacggagatc gcatctttga tttgtccagc ggtcattttc
     3541 acattgtctt ctgtttctag acgatctttg acttcattta atactagatc actaacgatc
     3601 atatctttat acgtattgat catttgcagg ttcgtattga catcattgac attcgctgtg
     3661 tctgattgcg gcagtgtcac gatcaattgt gcttgtgaac tgtattttgg tgtcaagatg
     3721 aaaaatgtta cgattcctga gatggccaag ccagcaaaca ttgagatgat gattgttgcc
     3781 aagtgtttgc gtaatgttcc aaaaatttct ttcaagctga ttgtctcttc cattttttct
     3841 ccactttcct atttattctc tagattcatt tgatctttta attctttttt cacacgatca
     3901 agttcttgat cgctgacttt ttgataggag atattatctt gcatgaagcc ttctccttgc
     3961 agctgatctt gcttgatcgt accaaatgcc tcccgataat ctaaagcgat ttttttcatt
     4021 tcatcaaagc tcatgtctgt tttcatattc gattctagag cattcaaaac ggattgatag
     4081 ttgctgacac cgtttagact caatactttt ttcgctacac cttctacgat ctttctttga
     4141 cgctcttgtc taccatagtc accatttgga tcttcataac gcatacgaga ataagataat
     4201 gcctgatccc cgttcaatgt gattttaccg attgtaaagt catagccatc ttgtgagaaa
     4261 gtgaggtcat tattgacttc gataccacca actgcatcaa caagttcttt tagccctttc
     4321 atattgatag agacatagtg atcgattggg atgtctacat atttttgtac ggtatccatc
     4381 gccatggcag ctccgccgaa tgcgtaagcg tggttgatct tgtcttttgt gtcacgacct
     4441 acgatgtcga catacgtatc tcgaggaatg ctgacgatcg ttgtctgttt gtcttcagga
     4501 ctgactgtgg caaccatcat cgtatctgat cttccttgat cgacccgacc taaatctcca
     4561 gtatcaatcc ccatcaatag aacagagaaa gattcttgtt tgtccagatc aactggtttc
     4621 gttcgttctc cttgggttcg ttccactgat tcgtaagttt tctcaataga atgtgagaga
     4681 tccagatata attttgctcc tactcctaca attgctaata ctaatacgat aagaactgct
     4741 aaaataatca gaaatatttt tttccctctt gattttcttc ttcgtcttgc catagtttcc
     4801 tccgtttgct aaccttgctt gaatcatcgc tttaactgtc aatagtttat attgctatag
     4861 cccatttgct gagcaacagt ttgtgctttt gttgcgtatg ctacgcttat tttttcattc
     4921 cggatctgct ctatttgact gagcgccgtc aaatattgat cgtaagtagc ggtggcagtc
     4981 acttgaccat cctttaacat cgtatcgaat aactgatcta gttgcgtgac ttgcgcgatc
     5041 tgggtatcag cgaatcctag atattgcata acaaccgttt tccaaggact atctttaaaa
     5101 aagctcatat tttcacgtac acgagcgaca tctgcacttg tcaccctttc tttgatgatg
     5161 acatcgtcta cagcttgctg ccagtttgat acatttttag taaataaatc gttgacagct
     5221 gtctggatct tcagttttga ttctgcacta tctaactgtg tcacgattgc tttcttctca
     5281 tcttggattg caacagcttc tttaggcaat tctgattctt tgatgtcgta atcatctgct
     5341 gaaagtttga cagaggatag cttatttgac aaacttgtga ttgtttcttc tgttatttca
     5401 gggtttagaa aaattttttc ttttgtacta tacagcttgt ctacttcttt tgataaagaa
     5461 gtcaaggtgt ctttttgatt ggtgatggca gattctgcat aattgatccg ttgctgatgt
     5521 tgccgctgat tattgatatg gtatccaaac aaacagatcg caatagcacc tgcacctacc
     5581 gccacagcag tcaatgactt gacgaatggc ttttccatag attcgctcct aagtattgat
     5641 gatagataaa ttaagatata attcacttac ataa
//
LOCUS       DAJSMK010000119         5668 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.127, whole genome shotgun sequence.
ACCESSION   DAJSMK010000119 DAJSMK010000000
VERSION     DAJSMK010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.127"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(450..1232)
                     /locus_tag="ON488_002428"
     CDS             complement(450..1232)
                     /locus_tag="ON488_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232568.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(1297..2133)
                     /locus_tag="ON488_002429"
     CDS             complement(1297..2133)
                     /locus_tag="ON488_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3232569.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(2151..3560)
                     /locus_tag="ON488_002430"
     CDS             complement(2151..3560)
                     /locus_tag="ON488_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HCR3232570.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(3574..5397)
                     /locus_tag="ON488_002431"
     CDS             complement(3574..5397)
                     /locus_tag="ON488_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3232571.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
BASE COUNT         1727 a         1235 c          919 g         1787 t
ORIGIN      
        1 cccttttata aaaagcaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga
       61 aaggagtcta acgttgtttg atataactta gactgatcgt taacttattt tttatatttc
      121 tacatagtta tctttagaac catttcagat acatatgaaa caattacata tgattttttc
      181 ataaaaaaac agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac
      241 taaaatcact acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct
      301 ccgtttcatt tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc
      361 cagtagctta tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg
      421 gtaaataaat gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg
      481 taatcagtta cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt
      541 aaccgaagtg gaatgtcttt accaacttgc tctgtcactg cattactgat acctgttaga
      601 ttagctaata aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc
      661 gtgattcctt tatcttcatt tacaagcttc caagtaggtg gtatagctgt gtatgtttcg
      721 atgaatgaat caattctttc atctatcgtc ttcccagtat ctacttctgt ctcattactc
      781 ttagatgaat cgattctttc atccatcgtc tgctccgtaa ctgcttctgt ctcattattc
      841 tcaccggaaa ctctcttcac acccaaactt atatattgtc catctttagt gtgcatagtt
      901 aaaattccca cgcttttact aataaattca ctataaccag ttctttcaat agagacttca
      961 atgtatttca cactatcata ctcaaaagaa aaatagacat gtaaaagcat tttgttgttt
     1021 acatctacat aataatcctt tgactctact tgagaccttc ctatacggaa tacagcttta
     1081 ctgtctgata tctctatacc agcatcctta ttattaatct gccaatctcc aagtagctct
     1141 tctggcaagc tagtagtttc ttgtgaacac tttaccactt cactggtaga ggtcgaaaca
     1201 ttcacctccg cactgttaga agaattttcc aaggaatcag gagccttagc acaaccaaca
     1261 agtctttata tattgtgcag ccgatatttt cttcattcag tacacccttg aaatatgcag
     1321 tgttagataa agcagttcgt cctgatttgc tgaggcaccc atctcttctt gaacgtactc
     1381 cttgattttc aaggccgccc gatactcttt cggaaaacgc tgcttcactg aagccagcaa
     1441 aaaatcatcc ttctccggca actcttcctt cttaatcatt cgggcaataa aaaactgtaa
     1501 atgcgtcaca aatcttaagt aaagcatcga atctttatca accttttttt cgggaaacag
     1561 atatcctagc atagccaaga tatcctttag tgctcttacc gagagcatgg tttcttccat
     1621 atttgcttgt tcactttggg catttacaat gtgaaacgca atgtttccag cctcctcttc
     1681 tggcaactga acattcattt ttttgttgat caattggata gcatagcagc cgatctcaaa
     1741 ttcttttggg taatactttt gaatttcaat cagcaggcga ttttgaaaaa caatgccttt
     1801 ttgactgcgt tcaatggcat gcttcaagtg atcaaccaag gtaaaaaata gacttttatt
     1861 cagcttaaag tcaaacttgg cgttggcata atcgataatt cgcttgacgc aaataattag
     1921 atcatccgga gcagcctcaa acagtttaat gtaatccttt tttagagcat cagaaagtga
     1981 atctaattta aatacttttt ggattttgtc agccggaacc aaatcgcctt tctttagttg
     2041 aaatccaatc cctttcccca tcaaaattac ttctttgcct tgcttatcta agcaaagaat
     2101 taaactgttg tttaacgttt taattactct cattagattc accgttctct ctaagctaag
     2161 ccatttcttg cgattacttt ttgataccaa aagaagcttt ctttttttat tcgttttaat
     2221 tctttaagat tctcatcggt tcggtcaaca tatataaaac cataacgctt attgaagcct
     2281 tgatgggtac taacaacatc aatcgctgac caaggtaaat aaccaaaaac atctacacca
     2341 tctgttaaag ctgcttgaat agccagaata tgtttggcta gataatcaat tcgatcctgg
     2401 tcattaattc gtctatcttc ctcaactatg tcgggtgccc catagccatt ttcagtaatt
     2461 aaaataggta aatcatagcg atcgtacaat ttcctcaatg ttaatcgtag tccagtaggg
     2521 tcaactaccc agccatatgg cgttttatct acataaggat tttcagctgc ccggtagaca
     2581 ccttcttctc ccaacatgat ctgttgatcc cccgctctag cggaaacatc tgatccgtca
     2641 tttttgctgg cagcgatggt ggcagttgaa taataattaa tcgcaataaa atcgggttta
     2701 ccggaggata aaattgcctg atcctctgcc tcaattttag gatataatcc acgatcattc
     2761 aaatagtttt caaacaaata attgtatttt ccccgaactg ctacatctaa gaaagaccag
     2821 cctctcaatg tttcccaatt atgggctgca attgcatctt ctggactgga ggtagcttga
     2881 tacatagccg ttaaattgat tgctggaccg atttttcctt taagattcaa ctgatgatac
     2941 aagtgaatta ctctagcttg agctaataaa acatggtgat taatttgaaa gagttctttt
     3001 tttgaaggca gctctccact tggtggcaaa ccaatcgctc caggatgaag gatcatcgtg
     3061 ttttgctcat taattgtcag ccaatagttc accttgtcac catactcagt aagcaatacc
     3121 tgtacatagt ccacaaaata atcgatagtt gctcgattta accaaccgcc ctgctcctct
     3181 agaaaataag gtaaatcgaa atggtacatg gtgacaatcg gttcgattcc ctgattcagg
     3241 cattcatcaa ttacttgatg ataaaaagaa attccctttt gattggtttt attattttca
     3301 atatccataa ttcgcgtcca agcgatggaa aagcgaaaag cttttaagcc taattcttta
     3361 aacagctgta tatcttcttt atagtgatgg taaaaatccg aggcaacttc aaaattagct
     3421 accccttctg tatgctgata cttgtcaata atagacggtt gtttcccatc ctcctgatag
     3481 gcaccctctg cctggtaggc actaatggag gcaccccata aaaacttctc tggaaatgct
     3541 gaaagctgtt tgtattgcac aaaaatcctc tccttaacta atttgcatca atggttcgtg
     3601 ttcctttaag cttccgcttg cttcactaat tcctgcgtaa ttttcactgt tggtcactac
     3661 cacaatcact gtatcatcgt agccagcgtt tctaatggca gcgaaatcgg cgttgattaa
     3721 taattgtcct gctgacacct gatctcctgc ttttacaaat acttcaaagg gttccccttt
     3781 taaattcacg gtgtcgatcc ccacatggat caataattca ataccttctt tagaacgtag
     3841 accaatcgca tgtttagatt ctaaaatagt aatgacttct ccctcaacag gtgaataaat
     3901 gctgttttct tctggatgaa tggctacgcc ctttcccaat agtcccttag aaaagacagc
     3961 atcgttcact tcagaaatag gacacacggt tccttttacc ggattttcaa caatgactgc
     4021 ttcggctatt gccgtttgct ctgattcatc agaagtatcg tcaaatccaa ttagataagc
     4081 aatgataaag gttgcaacaa aggcgattac acacgtaata attgcgtgaa caatattcat
     4141 tggattttct ccaataaagg ctggtaaggc tgctaagcca ggggaaacaa aggcatatct
     4201 gactaaaccg ctcaagccag catacaaacc agcaattgca ccaccaatca tggaagcaac
     4261 taatggtttt ttcagcttca aggttactcc atagagtgaa ggctcagtaa ttcccattaa
     4321 agcagtgatc ccagtggaca cagctagctg cttcaactct ttgtttttag ttttcgcggc
     4381 tacagcaaag gtagcacctg attgagcaat attagaagcc agcattcctg gcccattgat
     4441 catttcagaa cccgtactgc tcaattgcat agtagcgatt ggcgtcattg cccaagctgt
     4501 acccgtaacc accaaaaatg gctgcaaacc acccatcaaa aatggaatta accaagctgc
     4561 tttgccgtta atccattcag cccccattgc tataagatcg ttcagcaacg ttccaaacgg
     4621 tccaatgaca accaacgcta aaggccccat aattaaaaat accagcatcg gcttagtaaa
     4681 gaatttaata aacgaaggcg aaattcgatc cgcaaagggc tctacatagg acatgatcca
     4741 aacagtaaag ataatcggta aaactgatcc cgcataatct gcagctaata ccggaattcc
     4801 tagaaaagaa acggcatcgc cagtagaaaa aagctgtgaa atatttggat gaagcaaaat
     4861 gccagcaaca gtaatcgcca aaattgggtt gacatcaaac tttatggctg ccccataggc
     4921 taatagtact ggcataaaat aaaaggctgc atcagcaata gtattcaaaa tgatgtaagt
     4981 ttgactactg tctgatagta caccagtcaa agtcaagacg gccaaaatgg cttttaccat
     5041 cccggcacct gttatagctg gaatcatcgg tgtaaaggtg gtagaaatga cactaatcaa
     5101 tcttgaaata atactttctt gattgtctga agaggggccc tttttaattg aagttcccac
     5161 ttccttttga atttccttga aggctgtttg gacttcattg ccaatcacca cttggtattg
     5221 tccaccgcta tccaccacac taattacacc aagtgttttt tctaaggctt tcgtatcggc
     5281 tttcctttta tctttgagtt caaaacgcag tctggtggca caatgggtta agctgaccac
     5341 attttctttt cccccaacct gttgcaatac atttcttcct acttctctgt aatccattat
     5401 tctctctcct taaagcagta aaaaagacca agtcaaacca cgccccaatc aacattgaag
     5461 tgttagtttg tcttggtctt gcctgcataa tcagtaacat gccaataacg ttattttgct
     5521 gtaatccaat aatagcacat tatgatagcg caatcaacag ggaatttaat tttttatctt
     5581 ttcgtttgac cgtatagggt aatataacag ttagatcaca tcaactaggg tatatctgcg
     5641 tatacttact gctaaaataa gtatatct
//
LOCUS       DAJSMK010000120         5606 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.128, whole genome shotgun sequence.
ACCESSION   DAJSMK010000120 DAJSMK010000000
VERSION     DAJSMK010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5606
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.128"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            66..767
                     /locus_tag="ON488_002432"
     CDS             66..767
                     /locus_tag="ON488_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HCR3232572.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            764..1885
                     /locus_tag="ON488_002433"
     CDS             764..1885
                     /locus_tag="ON488_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HCR3232573.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1900..3132
                     /gene="pepT"
                     /locus_tag="ON488_002434"
     CDS             1900..3132
                     /gene="pepT"
                     /locus_tag="ON488_002434"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HCR3232574.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3264..4172
                     /locus_tag="ON488_002435"
     CDS             3264..4172
                     /locus_tag="ON488_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HCR3232575.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4207..4479
                     /locus_tag="ON488_002436"
     CDS             4207..4479
                     /locus_tag="ON488_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HCR3232576.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4490..5536
                     /locus_tag="ON488_002437"
     CDS             4490..5536
                     /locus_tag="ON488_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HCR3232577.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         1821 a          971 c         1217 g         1597 t
ORIGIN      
        1 ttttttattc ctagtctcct tattttattt ggaaaatgct ataattatct agaaggagtg
       61 aagctatgaa ccatttagat ttatctcagc gcttagccgc agtgggtgac tttgtccctg
      121 aatccgctcg tttagcagac attggatcag atcacgctta cttacccgtt gcattgatat
      181 taagaggaaa aatcgaatat gcagttgctg gtgaagtcgt tcaaggtcct tatgaatcag
      241 cacgtaagca agtcaaaaaa gatggattag aagaccgtat caccgtacgc cttgcaaatg
      301 gtctagatgc tatccagcca caagatggta ttacagctgt cacgattgcg ggtatgggag
      361 gttcactgat ccgagatatc ctagaagctg gcaagttgaa tcaacgctta agcggacaag
      421 aacgtttgat ccttcagcca aacatcggag agcgtacatt acgatcttgg ctgcaagaaa
      481 atcagtataa aatccaatca gaaaaaatac ttgaagaaaa taaaaaaata tatgaaatca
      541 ttgtagccga aaaagaacaa aaaccagtta cttacaatga aatggagctg atgttcgggc
      601 catttctgct tgaagagaaa agtgagatct tcaaatcaaa atggacaaga gagcttcaac
      661 aaagaaaagc tatccgtgaa cagctcaaac aagcagctaa tcaagaggca cgtcaaaaac
      721 aaatcgagca ggaaatccaa atgattgagg aggttttaaa gccatgacaa tcagcggacg
      781 cactttcatc caaaagtttg aaagctattg tcctcagtgg ctagctgaag aaggagaccc
      841 agtcggactg catatcggaa cattggataa gccaatccaa cgagtaatga tgacattaga
      901 cgttcgtcca gaagtggtcg aagaagcaat caagaaaaaa atcgatttgc tgattgctaa
      961 acatcctcca atctttcgtc ctgtaaaacg gctggttact gatcagccac aagaaaaaat
     1021 gtatgcagat ttgttgaaac atgatattgc cgtctatgca gcacacacga acatggatat
     1081 tatttgggat ggactgaatg actggttttg tgaacttctc ggtattgaag tggagagtta
     1141 tttagtaaag actcatgaga ttcattataa aaaactggcc gtttatgtac ctgtggatca
     1201 tgcacagaaa atgcgtgaag tattagctgc agctggtgct ggtacacaag gtgattatac
     1261 cggtacaagt tttacctcga ttggacacgg tcgatttact ccggaagctg gtgcacaacc
     1321 agcgattggg aaagtaggga agacagaaca agttcaagag gcaaaagttg aggttatttt
     1381 gccggaaact atcgaaaaac aagtgattca agccatgcgg tcagctcatc cttatgagga
     1441 acctgcttat gatcttttcg ctatagatga accagtcgaa atgtttgggt taggacgagt
     1501 aggtgaattg ccgcaagaaa tttctataga ggcatttgta gaacaagtaa aagaagcgtt
     1561 ccaactagat ggactgagaa tagtccagcc aaaaaatgca aaatcctctg tgaagcgcat
     1621 tgcgatttgc ggtggaagcg gtgaaaaatt ttatccgcaa gcaatcgccc aaagagcaga
     1681 tgtctatatc acgggagata tctattatca tacggctcat gatatgcaaa gcgctgggtt
     1741 gattgcaatt gatcccggtc attatattga atcgttatgc aagcaacgat ttatcgagaa
     1801 atttgaatct tggaaacaag aagaaaattg ggatattaac tttttcgttt ctgaaacaaa
     1861 tacaaaccca tttcaattta attaaaagga gagaatacta tgtacgaaaa tcttttgcca
     1921 cgttttttac gatatgtcaa aacagaaaca cgctccgatg caacaagcaa aacgactcca
     1981 tcgactcaga cacaagttgc ttttgcgcaa gaattgaaaa aagaattaga agagttaggc
     2041 ttagctgatg ttttctataa tgaagataac ggattcgtta tgggaacatt accaagcaat
     2101 gttgatcatg aagtgcgttc cattggattt atttcccaca tggatacagc agattttaat
     2161 gcagtaggag tcaatccaca aatcattgaa aactatgatg gcgagtctac gatcgtacta
     2221 gatgcggaag aacgctatac attgaataca aaagattttc caaatttgaa aaattatgaa
     2281 ggccacacat tgatcacaac agatggcagt acattactgg gagcagatga caaatcaggg
     2341 attgcggaaa tcatgactgc aatggagatc ttgatcaata atccttctat ccctcacggt
     2401 accatcaaag tggcttttgg tcctgatgaa gaaatcggtg tcggagcgga taaattcgat
     2461 gttgagcaat tcgatgtaga ttttgcttat acagtcgatg gtggtccttt aggtgagttg
     2521 cagtatgaaa cgtttagtgc tgctcaagca aatattacga tccaagggaa aaatgtacat
     2581 ccagggacgg caaaagatac aatgatcaat gctctacagt tagcaatcga ttttcataat
     2641 cagcttccag ccgatgaagt tccagaaaaa acggaaggat acgaaggttt cttccatttg
     2701 atggcattgg atgggaatcc tgaagaagct tctatgagtt atatcattcg cgatcatgat
     2761 cgtgaaaaat tcgaagcacg caaagcacaa atcacacata tccaagaaga gttgaatcag
     2821 cgatttgatc aagaacgaat caaagtagat atgtatgatc aatattacaa catgaaagaa
     2881 atcattgaaa aagatatgag catcgtggaa ttagcgaaac aagcaatgat cgagcttggt
     2941 atctctccag tgatcgaacc agttcgtgga ggaacagatg gttcaaaaat ctcttacatg
     3001 ggtattccga cgccaaatct atttgccgga ggagaaaata tgcacggacg attcgaattt
     3061 gtttctttac aagtaatgga aaaagcaaca gacgtgattg taaaaattgc agaattgaac
     3121 acaaagagtt aaaatcgaaa aagaacagct tatgacaagg cgttcgtccc aatgatggaa
     3181 tgtcatctgt ctaaggctaa agggcaggac aatggaattg gttgtcccgc cctctttttt
     3241 gaagagtaaa taggaggtaa agaatggaaa agctgctagt tttttataac aaaagttcag
     3301 ggaaagatga gggtgagaaa ttagcacgct ggtttcaaga ttatgtaaaa gaaaagcagc
     3361 cagaattata tgtagaacta gctgaaactg gcccatcgat tgatgatgcg gaattagtca
     3421 agaaagcaga agccatagaa gctgatactt tagtaattat aggtggagac ggcacgattc
     3481 atcatatcgt ccaagcgttc caaaaaacat tatctcaata ccatgtcgga ttacttccag
     3541 gtggaactgt caacaacctt gcacgtgttc ttgagattcc cctcaaaaaa gaagaagctg
     3601 ctgacgtgat cctggaaggc aatgtacgga aaatagacta tggtcaagtc aatgatgaag
     3661 tcattatctc tacactgaca atcggaatct tagcagatac agcagtttgg atcagtcaag
     3721 aagaaaaaca gcgttacggc tcgtggatct ttatcaagaa gttttttaag ttattgctga
     3781 agaagaaaaa atatcatttg gatttagaaa cagacgagga gcattggaaa ggaaaatccc
     3841 aactgttgac agtcacgatg tctaactccg tgggcggttt tacaaatttt gacgactcag
     3901 cgaccctaga tgatggaaaa tttcatgtaa cgatcgtacc ttccttagat attttccgat
     3961 ttatttttta tttgcctaga atcatgagag gcaaattcta tacgatcccc ggcattactt
     4021 atttcacagc caaacgcatg aaaatccaag cgcaggaaaa atctgtgggc actcgaacgg
     4081 atggagacac gacagatgat cttccagttg aattatctgt tgtatcaaaa ggattaacag
     4141 tttattcacc aaagaaagaa gaaaaagctt agaaatagta gttaacagaa agttggaaga
     4201 agagtaatgg atgtattgtt acacaatctt ttgtggtttt accttttcat tgtgaatttt
     4261 tacttatttt gtctgatggg gtatgataaa catcaggcta gaactagcgg ctggcgtgtt
     4321 cctgagaata atttgatatt tgtcagcctg ttaggcggtg gtttgggagg attgatctct
     4381 cgaaaagttt tccatcataa aactcggaaa aagaagttta ctataggatt cgctgcaggt
     4441 gtacttgttg atttgattct catttatttt ttccattaag gagcaggaga tgtcgtctaa
     4501 aggaacgaaa actaaaatca ttctgaatct gcttttgctg attgtgattt ttgccattat
     4561 ttattattta atcaatcaat catttgcaga tatctttgcc gaattgctgt ctaccagtgt
     4621 tgttgttttg gcagcggctg ttatattagg gacagtttac caaatcgctg aagggcgctc
     4681 aatcaaagaa attgctgaac ctttcgcgcc gaattttaca acgaaagatg ggttcttgac
     4741 ctctagctat attgcgtttt accgaatcgt ttcgtttggt acaggaacgc tgatctcgga
     4801 gatttatttt tataacaaaa aaggaatgaa gctatcccag ggagcagggg tgacagcact
     4861 ccatatgatt atgtacaaac tggcagtgat cacttatgca ttagctggct tggtcatcca
     4921 attctctctt ttttattcta atggtccatc aatgatctgg tttatcatcg ctggtatcct
     4981 tttgacgatc gtgattgttg cctttttatt ggcgatgtcc gtcagcttga atgttcaaat
     5041 attttttgtc agcttatcga ataagttatt taaaagtgag cgtttgcgga aatgggtgga
     5101 tacatgcaat cagcagatct actctttaag ggaaacggtc caaaccatta tccaagacag
     5161 gactgcgcta ttgcggattt atctatggaa tatgttaaaa cttgtatttt ggtatgtact
     5221 tccttatttg attctgattg aaaaccatcc taaaatagat tttctactga ccatttcgtt
     5281 tatcagcttt gcagtagtgc tttcaggggt tattcctacg cctgctggta ttggttcctt
     5341 tgaatttgtc tatttgttat tattcagacc agttgttgga acagttgacg cagtttcttc
     5401 gcttttactg tatcgtttca gttcctttat cttgccattt ctctatggat ttgtgtatgt
     5461 gattgctgaa cggcgaagag tgatcaaaga agaaataata gaagtaaaaa aagagaataa
     5521 agaaaatcaa gggtaggtct tttataagat ctaccctttt tatcaaatca aagaaaaacg
     5581 ttatggataa gataatttta cgtttg
//
LOCUS       DAJSMK010000121         5469 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.129, whole genome shotgun sequence.
ACCESSION   DAJSMK010000121 DAJSMK010000000
VERSION     DAJSMK010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.129"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..939
                     /locus_tag="ON488_002438"
     CDS             <1..939
                     /locus_tag="ON488_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR3232578.1"
                     /translation="RGRWKETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSES
                     LAIDILTFLTGISSRDGERFPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIAD
                     HIESFTDYDFAHLLFSDGYVEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSV
                     AMLIVISTFALDFIHTDRSIFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYF
                     VTQNTDDLLDEKLKNNLGLKFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQ
                     CLISDLYGRVGVIQFHPVFEELLHAFDTRPPVRKEV"
     gene            942..3125
                     /locus_tag="ON488_002439"
     CDS             942..3125
                     /locus_tag="ON488_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HCR3232579.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            3122..4123
                     /locus_tag="ON488_002440"
     CDS             3122..4123
                     /locus_tag="ON488_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HCR3232580.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            4138..5052
                     /locus_tag="ON488_002441"
     CDS             4138..5052
                     /locus_tag="ON488_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HCR3232581.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            5297..5413
                     /locus_tag="ON488_002442"
     CDS             5297..5413
                     /locus_tag="ON488_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HCR3232582.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         1727 a         1050 c         1157 g         1535 t
ORIGIN      
        1 cgtggcagat ggaaagaaac cttgccagag atttcccatg aaatcaatat cgtcaatctg
       61 acttctgatg agaaaaacaa aggcttactt gacccttatg taattatgaa aaataccaaa
      121 gattctgaat cactggctat tgatattttg acattcctta cggggatttc ctctcgtgat
      181 ggggaacgct tcccaatcct tagaaaagcc attcgtgcag taaccaatag tgaagtgcga
      241 gggttgatga aagtgattga agaattacgg gttgagaata cgccactaag taccagcata
      301 gccgaccata tcgaaagttt tacagactat gactttgccc atctgctttt tagtgatggt
      361 tatgtagagc agtctatcag ccttgaaaaa caactgaaca ttatacaggt tgccgacttg
      421 gtacttcctg acaaggaaac ttcctttgag gaatatacca caatggagtt actatcggta
      481 gcaatgctga ttgtcattag tacctttgcg ttggacttta tccatacaga ccgaagtatt
      541 ttcaagattg tagacttaga cgaagcatgg agcttcttac aggtggcaca agggaaaaca
      601 ctatctatga agctggttcg tgctggtcgt gctatgaacg ctggggtata tttcgtgacc
      661 caaaatacag atgacctctt agatgaaaaa ctgaaaaata acctcggctt aaaatttgcc
      721 tttcgttcca ctgaccttaa cgagattaaa aaaacccttg ccttttttgg tgtagaccca
      781 gaggacgaaa acaatcagaa gcgattgcgt gatttggaaa acgggcaatg ccttatcagt
      841 gatttatatg gtcgtgtcgg tgtgatacag ttccaccctg tatttgaaga actgctccat
      901 gcctttgata ccagaccacc tgtgcgaaaa gaggtgtaaa tgtgaaacca tcaatattaa
      961 acagaataaa atcaaactgg acgctgaaac gtctaggtaa agtggcaatg acagtggctt
     1021 tcacacttgt gattgccatt tttcttttag ccatgctggg aacggtggtt caagctgcgg
     1081 gcttggtaga tgatacggtc aatgtggcaa atgaatacag ccgataccca cttgaaaact
     1141 atcaactgga tttttatgtg gataatagct ggggctggct accgtggaac tggtcggacg
     1201 gaattggaaa acaagtcatg tatggactat atgccattac caattttatt tggacaatca
     1261 gtctttatgt ttccaatgcg acgggttact tagtacagga agcctattcc ttagacttca
     1321 tttccgctac agcagattcc attggcaaga atatgcagac ccttgcaggg gttacgccta
     1381 gtggactatc aacagagggt ttctatgttg gattcctttt actcttgatt ttggttcttg
     1441 gggtttatgt tgcctataca ggactgataa agagagaaac cacaaaggca attcatgccc
     1501 tcatgaattt tgtgctggtt tttatcctat cggcttcctt tattgcctac gctcccgact
     1561 acattaaaaa aatcaatgac ttttcatcag acatcagcaa cgctagtttg tcactgggta
     1621 caaaaattgt catgccccat tcagatagtc aaggcaagga cagtgtggac ttgatacgtg
     1681 acagcctatt ttccatacag gttcagcaac cgtggctact gcttcaatat aacagttcag
     1741 acattgaaag tattggtatt gaccgtgtgg aaagcctgct ctcaaccagt ccagattcca
     1801 acaatgggga agacagagaa aaaattgttg cggaagaaat tgaagataga agcaatacca
     1861 atatgacgat tacaaagacg attaaccgtt taggtacagt cttcttccta tttgtcttca
     1921 atattgggat ttccatattt gtattcctat taacaggaat catgattttc tcgcaggtac
     1981 tttttatcat ctatgctatg tttctgcctg tgagctttat tttaagcatg attccatcat
     2041 ttgatggtat gtcaaaacga gccataacaa agctctttaa taccattttg acacgagctg
     2101 gaatcacatt gattattacg acagcattta gtatttcaac catgctctat accttatcgg
     2161 ctggttatcc gttctttttg attgcttttc tacagattgt gacctttgca ggaatctact
     2221 ttaagctggg cgatttaatg agtatgtttt ctctacagag taacgattct caaagtgtgg
     2281 gaagtcgtat gatgagaaaa cctcgtatgc ttatgcacgc tcacatgcac cgtctacagc
     2341 ggaaacttgg acgctccgtg actgctttag gggctgggtc tgccattgcc agtgctacgg
     2401 gtaaaaaagg acagtcgggt tcgggaagtt ctgcgagtac acaagcagat cactctcgac
     2461 caaacgggca ggaaaaatca acactaggaa agcgtatcgg tcaaaccatc ggtacagtag
     2521 ctgataccaa agacagaatg gtagatactg ctggtaattt gaaagaacag gttaaggatt
     2581 tgccgaccaa tgcaagatat gcagtatatc aaggaaaatc taaagtgacg gataatgtcc
     2641 atgatttaac cagaagtatt tctcaaacca aagcggataa agccagtgga cgcaagaaac
     2701 agcaggaaca aagacggaaa accattgcgg agcgtcgctc tgaaatggaa caggtcaaac
     2761 agaaaaaaca gccagcttct tccgttcatg aaagaccagc cactaagcaa gaacaatctc
     2821 atgatggaca gacttcaagg caaacaactg tacaggcttc ctatagggaa tctcaacaag
     2881 ccaaacaaga gcgtccaaca gttaagtccg attcttcaag tttaaaaacg gaacgtcaaa
     2941 gtaatacagt tcaagaaaga acggttcaaa agccagtaac ttcaactgca ccaacagata
     3001 gagcttcaca acgttcaatc acaaaagaac gtcagtctac tgttcaaaga gtaccactac
     3061 aaaatacaaa aagtagacca ccaatcaaaa ccgccaccat taagaaaggc agtaagaaac
     3121 catgaagctg aaaactttag tgattggtgg ttcgggatta ttcttgatgg tcttctcact
     3181 gcttctgttt gtcgccattt tattttcaga tgaacaagat ggcggttttt ccaacattca
     3241 ctatggcggt gtggatgttt ccgcagaagt gctggctcat aagcctatgg tagaaaaagt
     3301 tgccaaagaa tatggaattg aagaatacgt caatatactt cttgcgatta tacaggtgga
     3361 atcgggtggt acagcagaag atgttatgca gtcctcggaa tccctcggtc ttccacctaa
     3421 ttcattgagt acagaagaat ccattaagca aggtgtgaag tatttcagtg agttattagc
     3481 cagtagcgaa aggcttggtg tagatttaga atcggttatc cagtcctaca attatggtgg
     3541 tggtttctta ggatatgtgg ctaatcgtgg gaataaatat acctttgaac tggctcaaag
     3601 tttctcaaaa gagtattcgg gtgacgaaaa agtgtcttac cccaatccca tagccatacc
     3661 tatcaatggg ggctggcgat acaattacgg gaatatgttt tatgtgcaac tggtaacgca
     3721 gtatcttgtc acaacagagt ttgatgatga tacagtacaa gccatcatgg acgaagctct
     3781 gaaatttgaa ggctggaagt atgtctatgg cggagcttcc ccgactacct cttttgattg
     3841 tagcggactg acacaatgga cgtatggaaa agctggaatc aacttaccac gaacagcaca
     3901 acagcaatat gatgtaaccc ggcatatccc attattggaa gcaaaagccg gcgatttggt
     3961 tttctttcat tctacctata acgctggctc ttatattact catatcggga tttatttagg
     4021 cgataaccgt atgtttcatg caggcgaccc tatcggttat gccgacttaa caagctctta
     4081 ctggcaacag catttagtgg gagcaggacg aatcaaacaa taagaaagga cgattcaatg
     4141 atgaaattcg gaaaaaatca gaatacagaa aaacagacac caaaggaaaa gaaacctcgt
     4201 gtctataagg tcaatcctcg taaaaaggtt gtgattgtcc tatgggtact tttaggactt
     4261 agtttcagct ttgcgatatt caagcacttt acagccattg atacccatac cattcatgaa
     4321 accaccatca tagaaaagga atatgtcgat actcatcatg tggaaaattt tgtagagaac
     4381 tttgcgaaag tctactattc atgggaacta aacgacaagt ccattgataa tcgcatagaa
     4441 aacctgaaag catatctgac agaggaactt caagctctga atgtcgatac agttcgtaaa
     4501 gatattcctg tatcgtcttc tgtaaaagga tttcagatat ggacggtaga agcagatggc
     4561 gacaatcaat ttgatgtaac ctacagtgta gaccaactca ttacagaggg ggaaaataca
     4621 aagaccgtcc actctgctta tatagtgagt gtctatgtag acagtactgg aaatatggtc
     4681 ctcattaaga atccgaccat tactagcata ccaaagaaat cagactataa accaaaagct
     4741 attgaaagtg agggtacggt tgattccatt acaaccaatg aaatcaatga gtttttaacg
     4801 acgttcttca agctctatcc tacagcgaca gccagtgaac tttcctacta tgtgaatgac
     4861 gggatattaa aaccaatcgg aaaagagtac atctttcaag aactggtaaa tcctatttac
     4921 aatcgtaagg ataatcaagt cacggtatcg ctgacagtgg agtatatcga ccagcagacc
     4981 aaagcaacgc aggtatctca atttgatttg gtacttgaaa agaacgggag taattggaag
     5041 attatagaat aacaaatatt ggtacattat tacagctatt ttgtaatcac gtactctctt
     5101 tgataaaaaa ttggagattc ctttacaaat atgctcttac gtgctattat ttaagtatct
     5161 atttaaaagg agttaataaa tatgcggcaa ggtattctta aataaactgt caatttgata
     5221 gtgggaacaa ataattggat gtcctttttt aggagggctt agttttttgc acccagttta
     5281 agaatacctt tatcatgtga ttctaaagta tccggagaat atctgtatgc tttgtatgcc
     5341 tatggttatg cataaaaatc ccagtgataa gagtatttat cactgggatt tttatgccct
     5401 tttgggcttt tgaatggagg aaaatcacat gaaaattatt aatattggag ttttagctca
     5461 tgttgatgc
//
LOCUS       DAJSMK010000122         5285 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.130, whole genome shotgun sequence.
ACCESSION   DAJSMK010000122 DAJSMK010000000
VERSION     DAJSMK010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5285)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5285)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5285
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.130"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            229..573
                     /locus_tag="ON488_002443"
     CDS             229..573
                     /locus_tag="ON488_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HCR3232583.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            574..993
                     /locus_tag="ON488_002444"
     CDS             574..993
                     /locus_tag="ON488_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HCR3232584.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVIFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1085..1435)
                     /locus_tag="ON488_002445"
     CDS             complement(1085..1435)
                     /locus_tag="ON488_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232585.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1401..2732)
                     /locus_tag="ON488_002446"
     CDS             complement(1401..2732)
                     /locus_tag="ON488_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HCR3232586.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2988..3554
                     /locus_tag="ON488_002447"
     CDS             2988..3554
                     /locus_tag="ON488_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HCR3232587.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3699..3786
                     /locus_tag="ON488_002448"
     tRNA            3699..3786
                     /locus_tag="ON488_002448"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3731..3733,aa:Ser,seq:cga)
     gene            4120..4686
                     /locus_tag="ON488_002449"
                     /pseudo
     CDS             4120..4686
                     /locus_tag="ON488_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            4799..>5285
                     /locus_tag="ON488_002450"
     CDS             4799..>5285
                     /locus_tag="ON488_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HCR3232588.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FM"
BASE COUNT         1927 a          890 c          999 g         1469 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgtaaaata
       61 aaaaaagcgt tagcaactat gcttaaaaag catatcgact gaataaacta agcattggac
      121 aggctgaaag actacattta aaatgaaatg cgaagaaaca atagaaaata aagttgcctt
      181 agaaccatag ttgaatcacc taacagtcgt gaagggagaa taagagaaat ggcagaaaaa
      241 caaaccgcag gacgagatca attaggagat tttgcaccaa aatttgcaga attgaatgat
      301 gatgttttat ttggacaagt atggtccaga gaagaattat ctgctcatca gcgtagtatc
      361 atcaccatat ctgcattaat ttcaggagga aattttgaac aattgccagc tcatctgaag
      421 attggcaagc aaaatggcat tactagtgaa gaaatagcag aaatcattac ccatttagct
      481 ttttatgtag gatggccaaa agcttggtca gcttttagtt tagcaaaaga aatctattta
      541 gaagaaaata gcgaagataa gaaagaggcg taaatgacga caaaacacga agaaatacac
      601 aatggcgtga tttttccagc aggtgaaaaa aacgaagctt acgctcaagt atttaccggg
      661 caaagctatc tgaatatgtt agtgaatgat cccgaagttt ctgttggtgt aggtaatgta
      721 atttttgaac caggttgtcg caatcactgg catgtccata aagacggcta tcaaatctta
      781 cttgtgaccg gaggagaagg ctggtatcag gaagaaggaa agccagcaag acgattaatg
      841 gctggagatg tcgtcgtaac gcacaaaggg attaaacatt ggcatggtgc gacaaaagac
      901 agttggtttg aacatttggc gatcactgct ggtaattcag agtttttaga acctgtaaca
      961 gatgaagtgt atgaaggatt ggaaaatcaa taatgtcaag cttgaacagc tcctgaaagt
     1021 agattttaat cgaactttca ggagctgctt ttttgattca gtcttttata aatagaaaat
     1081 agggttaata ataggaatga gaagcacgtc gaaagatctt aatattgata atcggctggg
     1141 catacatgat ttccacgtca tcaatcaaac tacctaacag atgataatct tcccgatcat
     1201 gtcggggatt acctaatagt tcttgatagt agatttccat actagggtcc cgaggattgt
     1261 tcagcaaatc agcaagtaca tctaaatctt ctggctgagt ttctgccgta ccctgtatct
     1321 ctatgaaaag cccttcctca gcaaattcta ctccaatacg tatttcagtt atttcatggg
     1381 aatataaata agtaagaagc tcatcgatga ttctttttga taattctttt tccaagtgtc
     1441 tttttttcct ttctgacagc ggtaaagtta tctagtatcg gtacaaggat acctgcaacg
     1501 aaaccagttg aaaaaccact gttatataga tttagtcctc cgtgcaaagt gctgacgtta
     1561 tggacaagag caatatgtag tacaccagct attacaccgt aaaaactgcc gtaaaaaccg
     1621 cttatgggcg cgagacctgt cccaaacaca gctgcaacaa gcatgccagt actggtgatc
     1681 tcatgaaaag ttccaaacaa agaagcaata aatattccga ctagtatcgg aaaactgttt
     1741 tttaaatgac aaccaaaagc actgaaaccc accgcagata aaatagcacc gatgacaggt
     1801 ccatttaact gaccgccaac cagcaaaaca taagaagaca gcatcagacc aactaagcct
     1861 atgttgatca aagtagcacc aataccagaa ttagcaatga aatcagttgt caattttcca
     1921 gatgaatcga aaatttctcg aatccccaaa agccgaaagg aattataata gaaaccaatt
     1981 ccgactgtca gcgaaaaaaa gccaaaaata atccaaatga gaggaaagtg atattcattg
     2041 aaaaccaatg tattttcgac gattgaatag ctgaataacc tcaaaacagc agtaaaagtc
     2101 atcgcaatca acccagaggt gaatccaata ttataaagtg tgaatccacg atggaaaact
     2161 aaagtttgag cagctaaggg cggaagaagt agaccaattg ctatgccagc taaattcccc
     2221 aataaaatac ctatcagtaa aggaaaacgc ataccaaaag tgatataact aacgaccggt
     2281 gataatgcgc taccaaacag tccgatcatg atgtactgag aaaaaggttt attgacaaat
     2341 acagcgtata gatacacacc taaaatgatt gagatagaat tataaaggtt tttgccaaaa
     2401 aaagagaaac cggtaactgt tagaatcgaa gcaaataagg gaccgtttaa aatcaccttg
     2461 tgccgataag ctaaaagcac agaaagtaag gtcaaaatcc ctacatttat gaatgcgctt
     2521 ccgaaaccgc ctaaagcaaa ataatctgtc aaaagattgc ttggcgaggt aagaatagtt
     2581 agcaatccac tccaattatc agtaggagta ttagaaagca agccaataaa aagaaaaaaa
     2641 acacctgtaa aaccaagata aaaatacttt cttttctgtg aaacgattcg tttttgagga
     2701 tgaatataaa taacgtcagt ttcgttttcc attacacacc ttctttttca ttttctttaa
     2761 ctataacttg aaatgaaaga tttggacaac tatcatttag gtcaaaacta aaaatgtaag
     2821 ggaacccatt gaatttaacc aaattttttt aattttgcaa aaaaaagtta aagaagactg
     2881 aaaaaaaatt taaaatataa cgttttgagt aaaatgtttg caaaaaatgc taaaaatagg
     2941 gtacaataaa acaacatata ctgcagtaaa gaagtggggg agttttaatg agaagaaaag
     3001 tctataccaa ggatcaaatt ctaaaagctg cttatgatgt tgttgcaaag gaagggttta
     3061 aaggatttac tgcgagaaat attgctaaaa agatggggat ttcgacacag ccgatttatc
     3121 tggaattcaa aaacatggaa gatttaaaaa atacgttgct ggattctatc tttgaacaac
     3181 taaaagaaga tgttttccct attgaacgta ctggtgataa aatcattgat ctcggtttga
     3241 actatatcta ctttgcaaaa aagcatcata gtctttacat ggcattgtac attgatgaac
     3301 atggggacgg aaagaaaatg catgattttt catacaatta tttccgtgaa atagttaaag
     3361 aagatgaaag atacaatcaa ttatcggatg aatatgtcga tgctctgcat actggtacat
     3421 gggtagcagt gactggctta gcgtcattga tgtcatcaaa catcatgcat ccaacagaag
     3481 aacaaatcat tgcactgatc aaacggacaa ttgactcgat tttagcatta gataatcctg
     3541 aaataatcag atagtgttct atcagtatga atttgatcgg taagtccgtt ggctgcaaac
     3601 tgtcaatgga cttttttgct aaaaaaagcg atttctgtta tttatctatt agaaataggc
     3661 ttgacatttc gtgaaaaaag tttaaaaata gtacttacgg aaggttggca gagtggtaat
     3721 gcaccggact cgaaatccgg cgaaccggct aataccggcg cgcaggttca aatcctgtac
     3781 cttccttata tcaacgatta gaggttgtga agaagctgtc ctgcatcaag taataagaac
     3841 ggccaaacaa aaatagcttt tcctattttt tcgtttgatt gggcttatta ccgcagatgc
     3901 aagcttttga acaccgtttg ttcggaataa ggggctgtga caagactttt gtcacagccc
     3961 cttattgttg tacttttaac ctacaatatt ttttgattcc ccctgagtac tattttttat
     4021 aaatgctagt aaatcaatct tctttggcct ttttttgata aaaaaaatac tagatgtaag
     4081 ataaaagtgt aaaaacgatt tgttttagga ggggaaacga tgtgtaccgc aatcacttat
     4141 gcaacgaaag accattattt tggaaggaat tttgattatg agatgtctta taatgaagtg
     4201 gtcactatta ctccaagaaa ttatcgtttc gattttagaa aggtaaaaaa tttagataaa
     4261 cattatgcaa tgataggaat agcagctggg gtatccaact atccactcta ttatgaggct
     4321 acaaatgaaa aagggttgag tatggcagga ctgaattttc ctggcaatgc tgattataaa
     4381 gaattacaag aaggaaaaga taacgttgca ccatttgagt ttattccatg gatactaggg
     4441 caatgctcaa ccatagacga agctaaagaa ttattggcta ctatcaatct agtcaatatc
     4501 gattttagtg aaaaactacc cttgtcacct ttacactggt tattagctga taaagaaaaa
     4561 tcgatagtaa ttgaaagtat gaaagatgga cttcatttat atgataatcc tgtcggtgtg
     4621 ttgacaaata atccgccatt tgattatcaa ttatttaatc tgaacaatta tcgctcgcta
     4681 tcaaatggaa cgagagtata aaatattttg tgtaaatgaa aaaatccata caaaaaagga
     4741 agtcccttct gtagaataaa gttaacgaca accaattcac agaaaagagg acttccctat
     4801 gaatgatttt actacagaaa ttgtgcaaac tctagtcact aaaggcgatt taaatgaatt
     4861 attccgttcg cacttagaaa aagcgataaa cacactccta cggactgaat taacggcttt
     4921 tttagattac gaaaaatatg atcgcactgg ttttaattca ggtaattcga gaaacggttc
     4981 ttactttcga tcaatcaaaa ccgaatatgg tgaattaaca ttggaaatac ctagagatcg
     5041 taatggtgag tttaaacaac aaactttacc agcctacaaa agaacaaacg atacattgga
     5101 aaccactatt atccatttat tcgaaaaagg tgttacgatg tctgaaattg ctgatttgat
     5161 cgaaaaaatg tacggtcatc actatactcc acaaaccatg tccaacatga ctaaagttct
     5221 gactgaagaa gtaaatgcct ttaaatccag agccttaaat gataagtatg tcgctatttt
     5281 tatgg
//
LOCUS       DAJSMK010000123         5239 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.131, whole genome shotgun sequence.
ACCESSION   DAJSMK010000123 DAJSMK010000000
VERSION     DAJSMK010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5239
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.131"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..2693)
                     /locus_tag="ON488_002451"
     CDS             complement(<1..2693)
                     /locus_tag="ON488_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HCR3232589.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWSNLRQ
                     KIISNNQAELNDSPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIERENPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIIQIELK
                     QVTAKDGFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGVSSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMESVKKESYLDPTVFEAEEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKESDWLIKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTAWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVQSSTLNNQIQLLEE
                     QIGVYETVKGSLMEEEPEKEGEDFSTIEFYSENTTKLYDIDS"
     gene            complement(2707..3924)
                     /locus_tag="ON488_002452"
     CDS             complement(2707..3924)
                     /locus_tag="ON488_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCR3232590.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLGDMMDVTSVKRIHQSDWTNSG
                     IRFLRARDIVSAAKNEEPSDYLYISEEKYNEYSKNSGKVSQGDLLVTGVGSIGVPLLI
                     TDDNPIYFKDGNIIWFKNEHKIDGNFFYYSFINNKIQKYIRDVAGIGTVGTYTIDSGK
                     KTPISLPTYDEQIKIGSFFKQLDHTIMLHQHELDLLKETKKGFLQKMFPKNGAKVPEV
                     RFPGFTGDWEERKLGEVVVFLNGRAFKQQELLDSGKYRVLRVGNFNTNDRWYYSNLEL
                     EEDKYANKGDLLYLWATSFGPEMWNEERVIYHYHIWKLKFLSKELDKQYLYTWLLTDK
                     EKIKESTNGTTMVHVTKGGIEQRTFQFPPDINEQQKIGAFFKQLDDTIALHQRKLDLL
                     KETKKGFLQKMFV"
     gene            complement(3914..>5239)
                     /locus_tag="ON488_002453"
     CDS             complement(3914..>5239)
                     /locus_tag="ON488_002453"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCR3232591.1"
                     /translation="SISPEYLFNVLADQAKQATFQLNDLNKAFVQLASTYNQFNGLFD
                     DVDLQSKKLGTDEQQRNVTITEVIKKLNDVEVLGHDGDVIGDAYEFLISQFASEAGKK
                     AGEFYTPHMVSDMMAQIVTLDQKERRFFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHG
                     QELNTTTYNLAKMNLILHGVDAEEMNLRNGDTLNKDWPTDEPYTFDAVVMNPPYSANW
                     SADTTFLDDSRFNRYGKLAPKSKADFAFLLHGFYHLKETGTMAIVLPHGVLFRGAAEG
                     VIRQKLLEDGSIYAVIGMPANLFFGTSIPTTVIVLKKNRQTRDVLFIDASREFVKGKN
                     QNKLSEENIQKILETYAERKDVEKYAHLATFDEIKENDYNLNIPRYVDTFEEEEPIDM
                     VHVGNDIKKIRQEQQVLEKELLEAISSLQTTPENEAWLQGALEVFKHEQ"
BASE COUNT         1410 a         1124 c          899 g         1806 t
ORIGIN      
        1 gaatcaatat catacaactt agtggtattt tcactataaa attcgatcgt tgaaaaatct
       61 tctccctctt tttctggttc ttcctccatc aatgaaccct tcacggtctc gtacacgcca
      121 atttgttctt ccaaaagttg aatttgattg ttcaaagttg aagattgcac catgtcatca
      181 ttgtaatcat cataagtcac taacgattca tacgcacgat tcaattcttg aaatgctttg
      241 acgtactcga tacggatttc aagtggcgta tgttcatcaa tggattccat ggatgaaacc
      301 tcttttaact taccatatgc ttgcttgaat ctttttttgg attcttggta acttggataa
      361 atcaaacccg attcttcttt agcttctgaa tacagttttg tcgcatcctc gacattcttc
      421 tccattgtcg ctggctttcg gaaagtaaca attagtcctt ttgttttttc aggatacgta
      481 cggttcgtac gtgaaaaggc ttggatcaat cctgcatact ctagattacg atccacaaat
      541 agggtttgaa tcgtaggggc gtcaaaacct gtcaatagac gatccactac gattactaaa
      601 tcgatttgtt tcccaaattg tttgaattcc gctctttttc gtgccaaacg attattgatg
      661 tctccgttat aacgctcaat gtctgctagt gaccaggcag tatcataata ctgattatat
      721 tcctcaataa ttttttgcat ttcttcttgt tgggcacttg aatctcggct attttcttct
      781 aatgaatagg taatagcgat tcgtgggaaa tcaggatcct ccatcgttcg tccttcacgg
      841 ataggctgat tgggaaactc ttttattaac caatcagatt ctttcgtcat ctctttgatg
      901 gcccgataat actttttggc catatcaatg gaactcgtgg ttaagatcgc agacttcgtt
      961 ggacggccat ttcgaaaatc aaattttgta taggcattgt ctggacggaa cattttatga
     1021 atgacttttt ggatatgttc ctctgcttca aaaacagtag ggtccaaata actttctttt
     1081 ttgacagact ccatttgatc gatcatacga ttgatctgtt ccggtgaata ctctgcatat
     1141 gtttctactt cttttaattt ccgatagatt ttattctcta atgaagtcgg ctccacggtg
     1201 ttttcatgct ctacttgaaa tcctaaaacc gagccatctt ctaatgcatt cttgatggta
     1261 taggtgtgca agacctctcc atactgatca tgggtcgtac gtgccaattg ccctttggct
     1321 tgtttccgat tctcagggaa aatcggtgta cctgtaaagc caaaccaagt ggatttcgga
     1381 aacatttttt tgatttcttc catattttca gcacttaacg ctcgatgaca ctcatcaact
     1441 acaaacacga tatgttgccc cattaatttt tggaagcgat tggttccttt tttctcttcc
     1501 tgtttctttg catatttcaa cgccgcatct agtttttgac gggttgtaat gatcacaaca
     1561 ttcgcattgg catctgccaa cagagtttca cttaactctt tggcacttcc tgttcccacg
     1621 atcaagctat tcgctttggc attaccagaa gaaaccccag tattaaactc cgaagcaaat
     1681 ttcgtaaact ctgtggtggt ctgattatct aaatctttgc ggtccactaa catgatcgtt
     1741 cgatcgatcc ccgattttcg tgctaaaagc ttagtagata caaaactagt caacgtcttt
     1801 cctgaaccag tcgcatgcca cacataccct gattgatgtt tatttgcggc aataaacaag
     1861 gcttgaatcg catgcacttg ataaggatgt aacaccatga gggttttatt gtcttgatct
     1921 tcactgacaa tcgtataatc cgcaatcaag cgatgggcat ctgggatatt tagcacttgt
     1981 ttgcaaaact catataagtt ttctaccttt ttattatctt tcgttcgcca actaaataaa
     2041 aacttaggat gcaaatcctt cggtaaggca tttgcaaaat accgagtcgt ttgttcattg
     2101 gaaaccacaa acaactgtaa ggtcgaaaag atattgttcc gaaacatgcc ttcttcagca
     2161 tattttttga tttgattaaa cgcctgataa aaaccatctt ttgcagttac ttgttttagc
     2221 tcgatttgga taatcggtaa gccattgatc aataaggtga cgtcaaaacg tcgatcccgc
     2281 gcttctatgt tacttccacg ttttgcaatt tgatggacca cttcataagt agagattcct
     2341 ccaccaatgt cttgattgga ataaaggata agtgagacag aacccaattg cggattttcc
     2401 cgttcaatcg tgatccgagc catcccattt tcacctttta accatttcgc agcatcaaat
     2461 ggggttttcg tccgtagcaa taattcggtt ttgatcgttt caaactcttt atcggtcaaa
     2521 ggagaatcat tcagttctgc ttgattattt gagatgattt tttgacgtaa attgctccaa
     2581 agatcttctt ctgattttag atccggacga tacgtccact gattatgtcc ttccccgagg
     2641 acacgaatca actgttcttc gacttccgct tcctcacggt gactaatttt cattcttctt
     2701 ccctccctaa acaaacatct tttgcaagaa gccttttttc gtttccttca gcaaatctaa
     2761 cttacgttga tgaagagcga tcgtatcatc tagctgcttg aagaaggcac caattttttg
     2821 ttgttcattt atatccggtg gaaactgaaa tgtcctttgt tctataccac ctttagtcac
     2881 atgtaccatt gtcgttccgt tagttgattc tttaattttc tctttatcag tcaatagcca
     2941 agtatataga tactgtttgt ccaattcctt agataaaaat ttaagtttcc aaatatgata
     3001 atggtagatt acacgttctt cattccacat ttcaggaccg aagcttgttg cccataaata
     3061 taagagatct cctttattag catacttgtc ttcctctaat tctaagtttg aataatacca
     3121 tctatcatta gtattaaaat tacctactct taaaacccta tattttccag aatcaagtaa
     3181 ttcttgttgt ttaaaagctc taccattcaa aaaaactacc acttccccca acttccgctc
     3241 ttcccaatct cccgtaaatc ctggaaaacg aacttctggc acttttgctc cgtttttagg
     3301 gaacattttt tgtaagaatc cttttttcgt ttccttcagc aaatctaatt cgtgctggtg
     3361 aagcatgatg gtgtgatcaa gttgtttgaa aaatgaaccg atcttgatct gttcgtcata
     3421 agttggaagt gagataggtg tctttttacc actatcaatt gtataggttc cgacggttcc
     3481 aatgcctgca acgtcacgga tatacttctg aattttgtta tttatgaacg agtagtaaaa
     3541 gaagtttccg tcaattttat gctcattctt gaaccaaatg atgtttccat ccttaaagta
     3601 aattgggtta tcatcagtga ttaataaggg gacacctatt gatccgacac cagttacaag
     3661 caagtctcct tgagaaactt tacctgaatt tttcgaatat tcattatatt tttcttctga
     3721 aatgtaaaga taatcggatg gttcctcatt ttttgcagct gagacaatat cacgagcacg
     3781 taaaaatcta atacctgagt tagtccaatc tgattgatga attcgcttca cagaagtaac
     3841 atccatcata tctcctaact tacgctcttc ccaatcttcc gtaaaaccag gaaaccggat
     3901 ttctggtcgt gtatcattgc tcatgtttga acacctccag cgcaccttgt aaccacgctt
     3961 cattttcagg tgttgtttgc agggaagaga tagcttctaa aagttctttt tctagcactt
     4021 gctgttcttg tcgtatcttc ttgatgtcat ttccgacatg aaccatatca attggttctt
     4081 cttcttcgaa agtatcgaca tagcgtggga tatttaagtt atagtcattt tctttgattt
     4141 catcaaaggt tgccaaatga gcgtatttct cgacatcttt tctttcagcg taggtttcga
     4201 ggattttttg aatgttttct tccgataatt tattctgatt tttcccttta acaaattcac
     4261 gactagcatc aatgaataat acatctcgag tttgacgatt cttcttcaat acaatcaccg
     4321 tcgttggaat cgatgtacca aagaacaagt tcgcaggcat accgatcaca gcataaatac
     4381 tgccgtcttc taataatttt tgacgaatga ccccttctgc agcaccacgg aataaaaccc
     4441 cgtgtggcaa gacgatagcc atagtccctg tttccttcaa atgatagaaa ccatgaagaa
     4501 gaaacgcaaa atctgctttg gattttggcg ctaatttccc gtagcgatta aaccgagaat
     4561 catctaagaa ggtcgtatct gctgaccaat tagccgaata aggtggattc atcactactg
     4621 catcaaatgt gtaaggttca tctgttggcc agtccttatt caacgtatcc ccattgcgga
     4681 gattcatttc ttcggcatct accccatgta aaatcaagtt catttttgct agattgtatg
     4741 tcgttgtatt tagttcttgc ccatgatatt taacgttatc tggatgagtt aagtagttac
     4801 gtacatttaa catcaaggaa cctgaaccca tggttgggtc aaagacacta aagaatcgtc
     4861 gttctttttg atccaacgtc acgatttgtg ccatcatatc agaaaccata tgaggcgtgt
     4921 aaaattctcc ggctttcttc cctgcttctg aagcaaattg actgatcaga aattcatacg
     4981 catccccgat cacatcccca tcgtgaccta aaacttccac gtcattcaat ttcttgataa
     5041 cttcggtaat cgtcacattt cgttgttgct catctgttcc tagttttttt gattggagat
     5101 ccacatcatc aaataaccca ttaaattgat tgtaggtaga tgccaattgc acaaaggctt
     5161 tgtttagatc gttcaattgg aacgttgctt gttttgcttg atccgctaag acgttgaaaa
     5221 gatactctgg tgagatcga
//
LOCUS       DAJSMK010000124         5184 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.132, whole genome shotgun sequence.
ACCESSION   DAJSMK010000124 DAJSMK010000000
VERSION     DAJSMK010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5184
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.132"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            137..748
                     /locus_tag="ON488_002454"
     CDS             137..748
                     /locus_tag="ON488_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HCR3232592.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="ON488_002455"
     CDS             821..1750
                     /locus_tag="ON488_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HCR3232593.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1819..2645
                     /locus_tag="ON488_002456"
                     /pseudo
     CDS             1819..2645
                     /locus_tag="ON488_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033645.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
     gene            complement(2693..3871)
                     /locus_tag="ON488_002457"
     CDS             complement(2693..3871)
                     /locus_tag="ON488_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCR3232594.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            3969..4067
                     /locus_tag="ON488_002458"
     CDS             3969..4067
                     /locus_tag="ON488_002458"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3232595.1"
                     /translation="MKERGLSGVKMVISDAHIGLTKAVKEYLLCAS"
     gene            4098..4499
                     /locus_tag="ON488_002459"
     CDS             4098..4499
                     /locus_tag="ON488_002459"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3232596.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(4706..>5184)
                     /locus_tag="ON488_002460"
     CDS             complement(4706..>5184)
                     /locus_tag="ON488_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HCR3232597.1"
                     /translation="AIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKEQQV
                     IESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFSNNQ
                     LFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVIK"
BASE COUNT         1639 a          877 c         1003 g         1665 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtctcct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gctt
//
LOCUS       DAJSMK010000125         5037 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.133, whole genome shotgun sequence.
ACCESSION   DAJSMK010000125 DAJSMK010000000
VERSION     DAJSMK010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5037
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.133"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            107..1248
                     /locus_tag="ON488_002461"
     CDS             join(107..335,335..1248)
                     /locus_tag="ON488_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCR3232598.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
     gene            1483..1935
                     /locus_tag="ON488_002462"
     CDS             1483..1935
                     /locus_tag="ON488_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232599.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            1949..2638
                     /locus_tag="ON488_002463"
     CDS             1949..2638
                     /locus_tag="ON488_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232600.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            2763..>5037
                     /locus_tag="ON488_002464"
     CDS             2763..>5037
                     /locus_tag="ON488_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HCR3232601.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFI"
BASE COUNT         1706 a          775 c         1030 g         1526 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc gtagaatcta actactaaga aaaggacgtg tccacgatgg caaaagccaa
      121 gaaaaaattt gatgaagact ttaagaagat gatcttagat ttaaaccagt ctggccaatc
      181 ggtcgaagaa ctggcagcgc aatatggtat cgctacacaa acgatttatc gttggaagaa
      241 gcttcataca aagaatgtag caaccggcat gactgaggca gaaatcctag cgatgaaaaa
      301 ggaaatggcc cgcatgcagg aggaaaacac tatcctaaaa aaggctttaa ccatattcgc
      361 tcaaaagtaa aaatgagtga tgtcttcgaa tttattcaat caaatgttca tgatcatgac
      421 gtaaaacaaa tgtgtaccgt tttggaagca ccgaaatcca gctactatga ctggaagaaa
      481 aagaaacctt ccaagcgcca atcagaaaac aaacgcttaa accgcttgat ttcaggaatc
      541 tactttgaaa acaagggtat ctatggtgcg cctaaaattc ataagattct tgttggccgt
      601 ggcgagacct tgtccttaaa gaaagtacaa atactgatga gaaaattagg cttgcgttca
      661 gtcaccctca agaagtacaa gcctggcaaa caagcgaaag ttaaaagtga aggacgtaaa
      721 aacctgttaa accaagattt taccactacg tcgatcaatc aaaaatgggt gacagatatt
      781 acctatattc ataccctaaa agatggctgg acctacctct ccactattca agacctccac
      841 acaaagaaag tcatcggttg gaagtttggc aagcagatga cgaaagaatt ggttatcgaa
      901 acccttgaca atgcgctctt aaaccaaaca ccctccgaga acttgatcat ccactcagat
      961 ttgggttctc agtacactag cgaagcctat gaggcaaagc tgaatgaatt gaacattcgg
     1021 cactccttca gtcgtaaggg ctgtccctac gataatgccg gtatcgaatc gtttcacgcc
     1081 tcactcaaaa aagaagaagt ctatccatca aaagcgtatg aaaactttga agctgcttat
     1141 ttagcgttat ttcaatacat tgaaggattt tacaatcgca agcgaatcca tagtagtatc
     1201 aactatttaa caccaaatca gatggaggag ttggcattgc aagcttagtt cctagctacc
     1261 acttacattt ttttggcgag atttccacag ggtttcaact tcatcgcttc gatcagcggt
     1321 caaacggttt tggtttgacc gctggtcgaa acgatgagat actcacccgc tggaatctcg
     1381 aaaaaattct cacaaatcgt gtccgaggta ttgactcaaa tccaccaatt atcttatcgt
     1441 agatatatat tataaattta ataagaaagc gaggtgagaa tcgtgaaaaa aacgatacta
     1501 agtatttttt cagtatttac aatattaatt gggggctatt ttcttttgaa tttagattct
     1561 gttaattcaa acgctcaaat aaaagatcaa agagtagctg aacataataa taaaaaaatg
     1621 agtttgacca aaaatatcta ttctatgtca gatgaagaat tgtataaaga atttggtgat
     1681 ttatccgggg aacagttaga agaaagtatt ccaggaatta gtgactcaga taaaattgtt
     1741 gtcttgtctg ctggtgggca attaatggga gatggcaaat ccgaattagt tagttataaa
     1801 caaaatcaca gacagtttat tgatgttaat actgattcca acgctatttc gattaaggat
     1861 ctaaaagagc ttttaaatag taaaagaaat gaattaaagc agataaaaga aactaattca
     1921 gtggaattag agtaaaggaa gattcattat gaaaaagatt tttggtgttt ctgttgggct
     1981 acttatgatg ttaacatttg gaaatgcagt atatgctgct gagaaagaag ttatttcaga
     2041 tccagagcag tacgcctcac gatactttgc tgattttgaa gaagaagata aagtacttgc
     2101 attgccagaa ggtggttttt taaaagggga agctaaaatt gtatctatgg ataatccaga
     2161 tataattcaa ggttcatata attcagaaac tgatcctgct tcagtttcag tgacagaagc
     2221 aaaaaaaatt gttgctgaaa aattcaaaaa tgatattgaa actactccaa ttatgcctcg
     2281 aggagcattt ccacccgatg ttggtactag cggacacctt cttgtactag caggaggagg
     2341 aagctataaa tcacagccat ttagtggtgc gggatggcgt tttggaggta tgggtgtaaa
     2401 accagctgat ggtacaggca actttttacg ttggaaatcc tacattgacg atggaagagt
     2461 aggaaatgta aatcaagcca acgcaactaa atctggttct attcaaggaa tggcattgta
     2521 tgctcgtgaa ggattcaaat actttgcacc aaacgggcct ggttggacaa tgaatatagg
     2581 tatttattac acttataatc ctgttgcagg tacgtattat gttgttcaaa atatttaata
     2641 aaacagcaca aagagatttc tttgtgctgt tttattattt ttagttgttg acaaacacta
     2701 aaatataaaa tataatcaac acataaacga acgtatgttc ggcaagaaag caggggattt
     2761 ttatggatga gatggtttta agtactcaga aatggctaaa caagaaatac agtaatgtta
     2821 cagggtttga taaggttcca gaaaatgggc gaacagggtg gcctacaatc tatggactta
     2881 ttgaaggact acaagtagaa cttggtatta ctaatctagt agctaatttt ggacctacca
     2941 ctgaaaaaat gtacgataat caggttactc ctaaatgggg caaaaatcta cctaaaaata
     3001 ttgtatttct tattcaaggt gccttttggt gtaaggggat taatccaggt ggcttcgatg
     3061 gggtatatac tccatattta gatactgctg taaaagagtt gcagactgat gcagggttta
     3121 atggaagcgc tgtaactgga gttttggatg cgaaatgggc caaagcgtta tttgatatga
     3181 gtgcttttgt tcttgttccc ggcggagata gtaaaattag aaaaatgcag caatggttaa
     3241 atgtaaatta tttagaatac acgggaataa tgccttgtga tggtatttat caaagaaatt
     3301 caaatcaagc attaattttt gcattacaag ctgaactagg atattctccc agtgaagcaa
     3361 cagggtctta tggtaatggg acaactagta aaacttatcc tgtgtctgaa ggtaactcgg
     3421 gaaactatgt aagaataatt caatatggat tatatgttaa tggttatttt gaagacggta
     3481 cattcgatgg tattttcact aaatatatgg gtttagaagt actggcattc cgaaaattta
     3541 tggtattgcc tgaatatact gaaatagcag atgttgttgt aataaaagga ctattgtcta
     3601 gcgctggaga tattagaaga tctgcagatg gcgcagatac ttctacgcaa ttaactagat
     3661 ctcaaatcca aacattggtt gataatgata taaaaatagt tggtagatat cttactggta
     3721 ctgttggaat tggaaaagat gaacgaaata agtatctaac tacagaggaa ttgaataata
     3781 ttttttctaa aaatttatct gtgtttccta tctatcaaga tggaggtgca gcattagctt
     3841 attttactta tgatcgtggc ttatcagatg gtaagaaggc tatagatgca gcaaaaaatc
     3901 taaatatacc attaacaaca gttatttatt ttgctgttga tctagacatg ttaggggaag
     3961 aaattcttgc atatgctgga gaatatttta agggggtatc tgctgtaatg tcatatagcg
     4021 ggtatcaaac gggtgtttac ggaacaagaa atgtttgttc tcaaataatc aataacgggt
     4081 atgcttcgtt tgcatttgtt tcagatatgt cgactggtta tagtgggaat ttaggttttc
     4141 ctatgcctag acaatggtct tttgatcaat ttgttgaatt taccatagga agtggcaacg
     4201 gagctgttgg tatcgattta atcgctacat cgggtagaga tagcggattt aatgagttat
     4261 caaatgatac taataatgat aattacattg ccaaatacaa tcagaaggtt ataaatcaga
     4321 tggtacgtgc gtatcaatat ctatcacaag ctggtcttga taatccttgg aaccctcatt
     4381 tgacatttta tagatatgta aattattctg gtttgtcatg ggacatcatt tcttctcctg
     4441 taacagagca tgatagaaaa atttatgatg aatataggaa taaattaact aatagcgagg
     4501 gcctgtataa ttattttata gatcctaata ctggttcaat aataggtttg cctcacttaa
     4561 ttgtgacgtt acaatcacag atgtttctag ccgacacaat caatgatagt gtttctgact
     4621 ttgcaggttg gttaggagat ttaatgactt gctggggtga agttaagaaa ttaggaatac
     4681 aaatggagca aggtgtattt gcattagtag gtacggctgc aggtggaaca tttagtctag
     4741 aagatttata ccaagatgtt gacgcggtaa atgtttatac cttagcaaaa agaaattctg
     4801 attcaacagc tttatcggct ttaaaaacgt actattgtga taagggtgct attgatagat
     4861 ttaatcaatt tgttaagaac agatttggtt cttcagataa aatcgcttca gtaacaaata
     4921 gtttattaga aaatgacgaa acagttgata tcttaggtgt agggataatt tcatttttca
     4981 ttgataaaat agttaataat tcacttggga cagattttac ttatcttgat tttattg
//
LOCUS       DAJSMK010000126         4951 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.134, whole genome shotgun sequence.
ACCESSION   DAJSMK010000126 DAJSMK010000000
VERSION     DAJSMK010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4951
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.134"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(334..696)
                     /locus_tag="ON488_002465"
     CDS             complement(334..696)
                     /locus_tag="ON488_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232602.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(770..1150)
                     /locus_tag="ON488_002466"
     CDS             complement(770..1150)
                     /locus_tag="ON488_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HCR3232603.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1214..2407
                     /locus_tag="ON488_002467"
     CDS             1214..2407
                     /locus_tag="ON488_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCR3232604.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            complement(2484..3068)
                     /locus_tag="ON488_002468"
     CDS             complement(2484..3068)
                     /locus_tag="ON488_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HCR3232605.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3269..4267
                     /locus_tag="ON488_002469"
     CDS             3269..4267
                     /locus_tag="ON488_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HCR3232606.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4379..4888
                     /locus_tag="ON488_002470"
     CDS             4379..4888
                     /locus_tag="ON488_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HCR3232607.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
BASE COUNT         1571 a          924 c          860 g         1596 t
ORIGIN      
        1 aacgactcag ttatcttatc atgtcgttag taacatgtca ataactattt tttaaatttt
       61 ttagaaatgt gatataacat ccacttcaga atcaacgctg ttaaatttat catgtatttc
      121 ttccttggtc aactataaat taagcattac tttgtgaaat gatttttcga tcaattatta
      181 ttattcgtta tacaaccgtt ttcaacatat tttgaaaata aaatgcacta aaaaactatc
      241 tttagcagaa catttcattg tattttttgg accaaacaat aaaaaaagaa gtttgaaaaa
      301 aattcaaact tctttgttcg cttaatctgt attttagaag aaaggcactc cctctacttc
      361 gtaagttcca agaacagagc gcatttgacc tggttcttcc caaatatatc cttcgcctaa
      421 ttcttctctt tgattctttt gttcagtttc aaagacaaac aacggaacat tttcctcttt
      481 aatatgtgta tttgtcaatt ccatcaaact aatcttgcta acatcgatat gaactatttc
      541 ttttaagaaa ttaagtatat tcgctaaacc agtctttcct tcagaaagtt ccgctaacgc
      601 aaattccaac ttgtcatcaa ttgaatggac caaaaatttt ttagtaccat cctccaaatg
      661 caacataatt gtaccagcaa ctcttttgct tgccaaaatt tccacctcga tcaacttgtt
      721 ctatggctta cataaaaatt ctagcacatt ttcagaaaaa atacactttt tatttcttat
      781 tttctttccg ttctagttca gataatgctt cttctatcca aataggtaac tgctccgcaa
      841 tagtggtaaa tccgatctta cgatttttat tcgtgaaata cctttttctg cgatatggaa
      901 cagctggatt tgttttttct aacgttctta aagataaact gatttttttg gaatattcat
      961 caatgtcgat gatctgaact gttactggct gtccgacttt taacaatgaa tggatatttt
     1021 tcgtataacc ggattgtact tctgaaacat gaataagtcc ttgcgtctcg ttatcaagag
     1081 aaacgaatgc gccataaggc tgtatccctg tcacttttcc ttcaattatt tgtccaattt
     1141 tataagtcat ctacttccct ctcttcgcat ttatcattat actgtaaata gctcaaaaaa
     1201 agaagcgacg aaaatgactg gaggtcttaa gatgatcgaa tttgataaac agatttcaag
     1261 aaaagataca gaaagtgtaa aatgggacgc aattgctgag acatatcaaa tggatgactt
     1321 acttcctttg tgggtagcag atatggactt cttgtctccc ggtggggtag ctaaagcgtt
     1381 tagtgaatac atcaaacatg gaatctttgg ttatgccact ctgtctgata aactatatca
     1441 ggctatcatt cattgggaac gccaacacca tgctgtggag ttgacgaaag aaaatatcgt
     1501 ttttacaagt ggtgtgttaa ccagtttagc tgcagcagta caaactttta caaaaccagg
     1561 cgattctatt ttgattcatg acccagttta tcctccattt tcctctatta tagaaacaaa
     1621 tcaacgtcac atcgttcgaa gctctttgct agaaaaaaat aatcatttca tcatggactt
     1681 gtctgacatg gagaaaaaaa tcgaagaaaa caatgtaaaa gcaatgattt tatgcaatcc
     1741 tcacaatcct ggagggcgtg tttggagcaa agaagaattg aaacagttaa gcgaattgtg
     1801 tttaaaacat caagtgattc tgtttagtga cgagatccat caagatttaa ctttattcga
     1861 tcatacattt acttccatgc taacgattga tcctaattta gatgatctac tagttgcttt
     1921 tacttccgca accaagactt tcaatctagc tgcaatcaaa aattcaatgg tatttatcaa
     1981 aaatccagag atgaaagctg attttgaaaa acatttagtg atgaaccaac agcacgaaat
     2041 caacactttt ggactgattg gaacccaagc ggcttatgag acgggtggag aatggttaag
     2101 ccaactgatt ccttatctag aaaaaaatgt tcaaacagtt aatcagtttt ttgaacagta
     2161 tcttccgaaa gtgagaataa tgaaccctga aggaacttac ttaatgtggt tagattttac
     2221 cgcctatatt tcagacgacc aagaattgga gaacactctt gttcggaaag gaaaagtcgt
     2281 attaaatcct ggcatcacgt ttggtccttc cggtcatggg catatgcgct tgaatattgc
     2341 ttgtccagaa gaaactttac tggaaggact taatcgaatc aagtatgctt tagagacaat
     2401 cgattaaatc atttattcaa aataaaagga cgagacctta ctaggtttcg tcctttttca
     2461 taattactcc gtaccatacc aaactattct gaaatttcaa ttgtttcaat cactacatca
     2521 tgtacaggtc ggtcttgtgg accacgttgt acatttgcga tttcatctac tgtgtccatc
     2581 ccttctagta catgtccaaa gactgtatgt cggaaatcta gccaaggagt tccgccacct
     2641 ttatacgctt caatgatttc tgatgggaat ccagcacctt ctagttgtcc aagcatatta
     2701 gctggcacat ttgtgttatt tacaataaag aattggcttc cgtttgtgtt tggacctgaa
     2761 tttgccatag ataaagctcc gcgaaggttg aacagttcac gactgaattc atcttcaaaa
     2821 ctttcgccat aaatactttc gccacccatt cctgttccag ttggatcgcc gccttggatc
     2881 atgaaatcag gaataacgcg gtgaaaaatc acgccatcat aataaccttt tttggaaagt
     2941 tcaatgaaat tttgaaccgt cttcggtgct agttcaggga ataattgaac agtaatgtca
     3001 ccacggtttg ttttgataac agcttttggt cctttttcac tttttaaatc tagttgtggg
     3061 aatgccatat tgtttcctcc taatatttgc atacttcata ataataataa cataatacct
     3121 aacctctcgt aaaaatacta gatttgtttt cttttatttt tcatcactag atacattcta
     3181 taacttaccg tttcgatttc gaattcaaac atttttgaga agcattctca attaaattct
     3241 gctatagtgt gaaaagggag gaatttttat ggaaatctat gacattacaa tcatcggtgc
     3301 aggtcctgta gggatgtttg ccgcttttta cgcaggaatg cgccaagcta aaacaaaaat
     3361 cattgacagt ctacctcaac ttggtggtca attagcaact ttgtatcccg aaaaatatat
     3421 ttacgatatt cctgggtatc cagcaataaa agcaagtgaa ttaatcgatc aattagaaaa
     3481 acaattaact acttttaacc atacattcca tttaaaagaa gaagttctct cgcttactcg
     3541 tgaagacgaa gttatcgaga ttactacaaa taaaggcatc cattattcca aagcagtcat
     3601 tttagcttta ggaaatggtt cattccagcc aagaaaattg aatttagata atgctgaatc
     3661 atttgaaaac cacggattgg attatttcgt gaatgatttg atgaagtatg ctggaaaaaa
     3721 agtcgctatt gctggaggtg gtgattctgc tatcgattgg acgttgatgt tagagcctat
     3781 tgcaagcgaa gtttacttga ttcatcgtcg cccggaattt cgtgcgcacg aacatagtgt
     3841 atcacgcttg aaatcttcat ctgtcaactt gcttactccc tatctcatcg atggattatc
     3901 aggcaataat ggggaactga cagatatccg gttaaaaaaa gtgaaaagtg acgagacgat
     3961 tgatttgatg attgattctc tgatcgtcaa ttatggattc tcttctaatt tagaacatct
     4021 ttcttcttgg ggacttgata gtaccagaaa tgccattact gtaaaatcag atatgtctac
     4081 ttctattcca ggcgtttatg cagctggtga catctgtacc tatgaaggaa aagtgaaact
     4141 gattgctact gggctcggtg aagcacctac tgcagtgaac aacgctttac actatattaa
     4201 tccaaaggaa cgaactcagc ctggtcacag cacaagctta tacgataaaa atcttcgtcc
     4261 tagttgattt tttatatctc tttgcatttc aagttaaacc cgaaagcagt ttcttgcatt
     4321 tttttcatgt tccgttaaca tgaaatagag aaagaaaaaa taaaggggga gcaataatat
     4381 ggtcgtcaaa actgagactt tagaagaaaa ggcaagagaa ctattgaagg aacgtggcgt
     4441 aactgtagaa gatatcgcac aacttgtcat gtttttacaa aaagactata tttctgattt
     4501 gactttggcg gattgtactg aaagtgtcaa cagcgtgcta acaaagcgtg aagtacataa
     4561 cgccattatc actggaatcc aattagatat attagcagaa aagaaaaaat tgatgagtcc
     4621 gttgcaacat attatcgaag atgacgaagg cctttacggt atcgatgaga tcctagcctt
     4681 gtcaatcgtg aatgtttacg gtacgatcgg ctttacgaat tatggttata tcgacaaggt
     4741 gaaacctggt attttaaaag aactaaacag ccacgatggc gttcatgtcc ataccttctt
     4801 agatgatatc gtcggagcga tcgccgctgc tgctgccagt cgattagcac acaaagaacc
     4861 agaaaaaaga agtcgcctta ctcaataatt caacaaaaaa agaaagaaaa cgtctattta
     4921 gacgagttct ttcttttttg tttgtttcaa g
//
LOCUS       DAJSMK010000127         4906 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.135, whole genome shotgun sequence.
ACCESSION   DAJSMK010000127 DAJSMK010000000
VERSION     DAJSMK010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4906)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4906)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4906
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.135"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            292..1215
                     /gene="truB"
                     /locus_tag="ON488_002471"
     CDS             292..1215
                     /gene="truB"
                     /locus_tag="ON488_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HCR3232608.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1219..2160
                     /gene="ribF"
                     /locus_tag="ON488_002472"
     CDS             1219..2160
                     /gene="ribF"
                     /locus_tag="ON488_002472"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HCR3232609.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2512..3297
                     /locus_tag="ON488_002473"
     CDS             2512..3297
                     /locus_tag="ON488_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3232610.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3310..4161
                     /locus_tag="ON488_002474"
     CDS             3310..4161
                     /locus_tag="ON488_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HCR3232611.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4285..4737)
                     /locus_tag="ON488_002475"
     CDS             complement(4285..4737)
                     /locus_tag="ON488_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232612.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
BASE COUNT         1627 a          803 c         1050 g         1426 t
ORIGIN      
        1 aaaaagactg gaagaatggc cagtcttttt tttcgttttt gggaagtgaa aaccaaacta
       61 tttacctgta agccacccat aaatccaatc aaatggtgca aagaaaaaat cttccattct
      121 attccctcct ttaaaaaagc ataacatgat ttctatttac gtgagcatga attttgttac
      181 gtttttattg ccgaaaaata aaaaccgttc attatgatgt caaattcgtc agtaattgat
      241 gcaatgtgtt ataataattc agttaaatca aaaatgaaat ggagaaaaga catggacggg
      301 ttattacctt tatggaaaga acgcggaatg acaagtcatg attgcgtatt caaattaaga
      361 aaaatcttac atacgaaaaa aatcggacat gggggtacgc ttgacccaga cgtagacggt
      421 gtgttgccca tttgtattgg aaaagccaca aaagttatcg aatatttgac agattctggg
      481 aaaatctatg taggcgagat aactctaggt ttcagtacaa cgacggaaga tcgatccgga
      541 gaacgggtag aaacaaaacc agtagatatg tctttatctg aaaaaaaaat agatgaagtg
      601 atggcttcat ttattggtga gatcacccag ataccaccaa tgtactcagc ggtaaaagtc
      661 aacggtaagc ggttatatga atatgcccgc aataatgaaa cagtggagcg tcctgttaga
      721 aaggctcaga tttaccgttt tatccggaca agtgaattga caagagacga agtgacagga
      781 accatttctt ggcgcttcga agtagaatgc gggaaaggaa cctatgtccg cacattagct
      841 gtagatacag gcaagaaact tggttaccct gcgcacatgt ctgatctgac ccgaacagca
      901 agtgccggta tgtcccagaa ggatgctctg acattagaag aagtagctca agctgtgaaa
      961 aatgggacaa tcgatgattg tttgctgcca atagaaaaag gagtggaacg gttcaaacga
     1021 gtagatatta ctgatgaagt atggcagaaa gtaaaaaacg gtatgagact tgattatact
     1081 gtatttgcgc tcccagaaat gccgtcagaa gaaattgctt tgttttataa aggaaaagtt
     1141 gtcagtattt atcagccaaa cccgaaagaa aaaaacaaat taaaacctag taaagtattg
     1201 agaaatgagg aataacgaat gaatatcatc aagatcagac atccttacca atcagaacaa
     1261 attccagaag acgatgtcgt tttagtgctg ggatttttcg acggcgtgca tatcggacac
     1321 cagaaagtca taaagacagg tatggaaatt gcacaaaaag aaggattgaa attagcattg
     1381 atgactttca atcagcatcc atctattgtc tttaaaaaga tcgatcctag cagcgtgaaa
     1441 tatttgacta gccttaagca aaaagaagaa aaaatggccg ctttgggtat agattattta
     1501 tatgaagttg attttacttc ttcttttgct catttagcac cgcaggaatt tgttgatcaa
     1561 tacatcgtag ggttacatgc aaaatatgct gtttccggtt ttgattatac gtatggacca
     1621 aaagacattg cagatgtcgc tcattttcct gaatatgcca aaggaagatt caaaatcgtc
     1681 acagtttcta aagaagaaga acaaggtgaa aaaatcagct ctacccgtat tcgtggatta
     1741 ctagacagcg gacaagtaaa agaagcagca aaactattag gttgcacata tgaggtagaa
     1801 ggggtagttg tccatggcga tgcacgaggc agactactag gattccctac agcaaatgtc
     1861 aaagtaaaga gcacggttca tttgcctaaa gaaggtgttt atgtgtcgga aataaaaatt
     1921 ggggaaacat ggtatccagc catgggttca attggacata atgatacatt cggtgaagga
     1981 cgggagctga ctgtagagtt gtatattttg gactttaatc aagatatcta tggtgaacat
     2041 gtcgcggtac gctggaatca atttttaaga gatcaagtga aattttctag tgtagaggaa
     2101 ttgattgaac aactcaagga ggatgaacaa gcaacagctg aatatttttc tcagcaataa
     2161 aacattatgc ataaaatctc ttgtttatgt ataactagca attacaataa aatgggtgat
     2221 aaataagccc aggaaagggg ctgtgacaaa agtcttgtca cagccttttt ttccaaataa
     2281 atggtttttc agaagtagct tcttcggaaa taagccgaaa tttcttgaag ctgaccactt
     2341 ctgtcacaac ctctttcttt atagaaataa aaggacacta gcaattcatg aaaacgattg
     2401 ctagagcgta tcatttgctt tagactatat atcttggtgt acactcactt taaggcggaa
     2461 ataaaagtta tccgtaataa caggtttagg tatgaaaaag gagtgggtac tatgtacaag
     2521 gaattagaaa acaaagtcgc agtagtaact ggtggctcaa aggggattgg aacagcgatt
     2581 gctcaacgat tcgggaaaga aaaaatgaat gtagttgtca actataactc ggataaagaa
     2641 ggagcagaaa aagcagtcaa agcaatcgaa gaggcaggcg gaaaagcagt ctctgtacaa
     2701 gcagatgtca gttctgaaga aggaatacag cgtttacttg atacggcttt agaaaatttt
     2761 gggacactgg acgtttgggt taataatgct gggatggaaa atcagcatcc aacccatgaa
     2821 cttagccttg aagattggga aagagtgtta aaagtcaatt tgactggcgt ttttatcgga
     2881 acgaaagcgg ctttaaatta ctttacagag aataataaaa aaggaaatat catcaatatg
     2941 tcttctgttc atgaacagat cccatggcca acgtttgctc attacgctgc ttcaaaaggc
     3001 ggggtaaaat tatttaccga aacggtagca atggagtatg caccgaaggg aatcagaatc
     3061 aatagtatag gccctggtgc tatccgtaca cctattaatg cggcaaaatt tgatgatcct
     3121 gaacaaaaag aactcttgga aagtatgatc ccactaggac gcgtaggtga accaaaagaa
     3181 atagcggcga cagctgcatg gttggcttca gacgaatcca gttatgttac aggtattaca
     3241 ctatttgcag atggtgggat gactttatat ccttctttcc aaggtggaaa aggataaggg
     3301 tgaataaaaa tgggtttatt gattgcattg atcccggcag ttggctgggg gatccagcca
     3361 ctgattttga aaaagattgg tggcagacca acaaatgaga tattaggaac tggtattgga
     3421 gcggtgcttg tcggcttact cgttcaatta ttcgcttctc cagctggtat ttcagtgact
     3481 acatttttga ttagtttact ttctggtgca ttttgggtta ttggacaaac aggacagtat
     3541 acatctttca acttgattgg tgtttctaaa acgatgccaa tttcgactgc attacagtta
     3601 gtcggaacct cgttgattgg tgtcttcgct tttggagaat ggtctggaag tatggggaaa
     3661 atcattggag cagcagcaat cattcttctt gtatttggtt ctgctttaac ggcaatcagt
     3721 gatgatcctg gaaaaaaagg cggtatcaca aaaggaatta gtctattagc atcaacaagt
     3781 attggttatt gggtatacag tgcattgcct aaactagttg atgcaagcgg actttccatt
     3841 ttctttccgc aaatgatcgg tgtcttttta ggggcagtga tttatgtgat tttccgtaaa
     3901 ccaaccgcat tttctgaaga caagagttgg aaagcaacga tcgttggagc catctttagt
     3961 gtgtcagcat tggcttatat tttttcagca aatgaaaatg gggttgctac tgcatatatc
     4021 attacacagc taaacgtagt tatctctaca ttaggcggta tgtacatcct gcatgaaaat
     4081 aagacaccaa aagaaaaaaa attaacgatt atcggattat tgctgatcgt agtaggaagc
     4141 atggtcacgg tctttatttg aggataaaga tggtaaaatt tcatttatta aaaaaatatt
     4201 tgtttgaacc aaacagtaag tacttataaa aaaatagcgc tagaatttcc aacatctctg
     4261 gaatttctag cgctttttaa ttgtttaaga tacaagggaa atatctgtct ggatcaataa
     4321 tttttcattg atccattgac taaagtttac gacataattg aagttaccac cgattagtat
     4381 ctccgcatga ttgtctttat aaagatcgta ttgtaaaaga cggtcttttt tatttgcgta
     4441 aacatcgtta tggtactgga ctaattgttc tcggaattga ttgattgctg taaaatcacg
     4501 atattgaagg ttgaaacgca tcgtgattgg tgcatttagc atgaatcgct gcatttcttt
     4561 tgctgcttcc tctgcttgat ctccgtatag gaactcaaaa agattacgtt cagaaaattt
     4621 ccattgcccg ccaacctttg ttccttttag ttttccttca tgaagataat ttctgataga
     4681 acgtgtagta acacctaatt gttcggctaa ttcatttact gagtaaaaat ctttcaatgt
     4741 tcaccctcct atgtgaatgg ttctactgac ttagttgata tttgcttaat cacgaaatgt
     4801 agaaagaacg attttaatta aggtcattgt aaaaatcaag tcagaaaatt ctaactttta
     4861 tttctctaaa gaaattcgtt ctctcctaaa gtgatattat atttaa
//
LOCUS       DAJSMK010000128         4823 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.136, whole genome shotgun sequence.
ACCESSION   DAJSMK010000128 DAJSMK010000000
VERSION     DAJSMK010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.136"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(69..1217)
                     /gene="nagA"
                     /locus_tag="ON488_002476"
     CDS             complement(69..1217)
                     /gene="nagA"
                     /locus_tag="ON488_002476"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HCR3232613.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1293..2129)
                     /locus_tag="ON488_002477"
     CDS             complement(1293..2129)
                     /locus_tag="ON488_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232614.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2313..3530)
                     /locus_tag="ON488_002478"
     CDS             complement(2313..3530)
                     /locus_tag="ON488_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HCR3232615.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3679..3858)
                     /locus_tag="ON488_002479"
     CDS             complement(3679..3858)
                     /locus_tag="ON488_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232616.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3913..3996
                     /locus_tag="ON488_002480"
     tRNA            3913..3996
                     /locus_tag="ON488_002480"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3947..3949,aa:Leu,seq:gag)
     gene            complement(4236..4814)
                     /locus_tag="ON488_002481"
     CDS             complement(4236..4814)
                     /locus_tag="ON488_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232617.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         1472 a         1004 c          776 g         1571 t
ORIGIN      
        1 actagaacac aaaaaaaacc ttaaaaccaa acttaagaag tttagtttta aggttaactt
       61 aaattatatt atgcgtggaa acgttccacg ccatctagat aagttgcttc caatgtcata
      121 tcagggttca atacgataaa gtctgcatcg cgtccttgag cgatttttcc acatgtatca
      181 tcgattttac agctgattgc tggaatcaga ctagccatca tgactgcttg ttctggtgtt
      241 gctaatcccc agtctacaac atttttaatt gcttctttca atttcaatat acttccagct
      301 aagttgccag attctagacg tgctgttcct tcttttacta ctactggaaa ttcgcctaaa
      361 ttgtaatttc catcaggcat cccaccggcc atcatacagt ctgtaattaa tgcgacatga
      421 tcatgtcctg ctttttccat taggattccc gcagcatttg gatgtacatg atggccatca
      481 caaatcaatt cagaaaagac atgttctaaa gataataacg cacccaccat acctggttcg
      541 cgatgattca atccacgcat accattgaaa gcatggacaa atacacttgc gcctgcttca
      601 acagcttttt gcgcttcttc tagtgtagca ttactgtgtc ctagagaaac aactactcct
      661 tcttcagtca cttgtttgac aaactcttct acaccttgac gttccggtgc taaagcaatt
      721 tttttgatta aaccacctga agcttcttgc cattcatgga aagtatccaa atcaggatcc
      781 ccgaaataac ttgggttttg tgcccctttg tgttcttctg tgaagaaagg accttcaaaa
      841 tagattcctt tgattttagc tcctggtgct tcctgataca ttttgccgat tgtctcagct
      901 acatctttta aacgttcttt gcttgacgtc aatgttgttg gtaaaaatga agtcactcca
      961 caagataaca gaccttcaga catcactttg atgccttctg catcattatc cattacatca
     1021 tgattcatat agccgtgaat atgtgtatct accaaaccag gagcaatcca tttgccgctt
     1081 tggtcaatga tgttgacttc tccctcaggt agttctttgg tgtattcacc aaaaagtcca
     1141 tcggtaattt caagatagcc tgcatgtttg acacctgacg ctaaaaagaa tttgtcagca
     1201 tagataaaag ttctcattct attctctccc tttgtttttc tacctctaaa gtactcttat
     1261 ttagagaaga agtcaagaat ggtctacacc atttacaaat tttttgaaat ttgtttcaca
     1321 gcttgtgcta agccttcata gaatgctgct ctttctggtt cttctttacg cttgtatatt
     1381 aagcttttaa gcacaaataa atcattgagg taatagtagc tattcttctc ttgagcccaa
     1441 tagattcctt gattcacctg ttctaacgct tcgtcgattt cattttgatg gaataagaaa
     1501 tttccataat tataaaaaat ttgcgaaaat tcactttttg atcgttcatc agctgattga
     1561 tgcagcagtt ggatgcttcg actcaaatag tagcgtgctt cagccgtttt tcctgccaca
     1621 ccatatattt ttccgataca actaatcagt tgtatttctg tgtcagaaac atggattctt
     1681 tctttttggc tagagtagct taatgcttct ttcaaataat aaagggactg agagatattt
     1741 tgacgcaacg tgaattcgca aacaccgaga taataataat agcgttgaaa gtcagttgct
     1801 tgatacagat tttcagaaat atcagaagat tttagtactt gttctaactt ccgataatca
     1861 cgtttttgga aacaactatc caacagttca aataatttat cgtttgtccg agtagttttt
     1921 cgagagagat tcatcacatg atcaatcgtt acccctagcc gttgacaaat ctgcatcatc
     1981 accaatacat tcggcagttc ctcattattt tcgatccgac ttaatacact ttgtgaacaa
     2041 atatcatgcg aaagcatttt ttgcgtcatt ttttgttctt ttcgaatctc tttaatgatc
     2101 gttccaaagg actcgattaa cgtttccata agtatcctcc ccaaaatatg cgtattcgca
     2161 ttctattcgt attttacttt aggaagtcgc aaacttcaag aaaagacttg caactaaata
     2221 atatacttta gttatttaag aaaactccac tagaaagaga gcctcagtgt gtttgtctgt
     2281 ggccctccta ctgaaaaatt tggtttttaa aatcattttt ggcgataggt tgctaggaat
     2341 tctctcattt tcttagctgt ttgtttcaaa tcatccattt taggaagata aacgattcga
     2401 aaatgatctg gctggttcca attaaatcca ccaccatgta caagtagaat atgatgttca
     2461 tgtaaaaagt ccaaaacgaa tttttcatca tccaaaatat tgaatcgctt tgtatcaatt
     2521 tttgggaata tataaaaagc agcttttggt tttacggctg aaagaccagg aatatcattg
     2581 attgcattat agatatattc tctttgttca tagatccttc cgcctggcag gagcagctca
     2641 tcgacacttt gataaccgcc tagcgcggtt tggataattt gctgagacaa tacattggaa
     2701 cacaaacgca tggaggacaa catattcagc ccttctatat agcctttgac gtgtgactta
     2761 tctccactta ggaccatcca gcctactcga aatcctgcta cacgatgaga tttggataga
     2821 ccgttcagcg taacaacgaa caaatcaggc gctaatgtag caatcggaat atgttctaga
     2881 ccatccatca ctaagcgatc atagatttcg tcggaataaa taatcaggtt attttgtcga
     2941 gctacttcaa cgatttcttc taataattct tttggataaa gtgccccagt aggattatta
     3001 ggattaatga taacaatagc ttttgtccga ctcgttattt ttgatttgat atcatcaata
     3061 tcaggatacc attctgcctc ttcatcgcaa atataatgaa caggtgtgcc tccagctaat
     3121 gcaatagaag ccgtccacaa cggatagtcc ggcattggaa ccagtacttc atctccattg
     3181 tccagcaacc cctgcataca catcgtgatc aattcgctca ctccgttgcc ggtgtagata
     3241 tcattgatcg tcacattcgg aaaatgtttc agttggcaat attgctcaat tgcttttcta
     3301 gcagaaaaga tccccttgga atctgagtag ccttctgagt cacgggcatt catgatcaaa
     3361 tcacgaatga cttcgtttgg tgcttcaaat ccaaaaggtg cgggatttcc cgtgttcaat
     3421 tttaaaatac taatgccctc ttcttgcatc cgctccgctt cttctagaac gggaccgcga
     3481 acatcgtaac tgacaccttc taatttgttg gatttttcaa attctctcat cacttagcca
     3541 atccctcatt tcaaaaagtt agaactttcc aaattttttg ttatttacta tttcaatatc
     3601 atactccatc ctagaaaatt ttgccactta tttaggaaaa acgtaagtat taaaaaaaca
     3661 caaacaagcg ttgagaactt aattgtcatg atagtcattc catagattcg ctgcccaatc
     3721 cattgcaatt ccacaaatga ttcctagcat aaaaccaagc aaaaaacgtc cgaatgcaag
     3781 tccaatcaat acacctaaga tcattcccag tcctgaaaat tctccgtcat atttctccat
     3841 cttaataagt cctcccattt ttgagcttga caactatgta aaacctcgct atcattagtg
     3901 tgttattatt acgcagatgt gttggaattg gcagacaagc atgattgagg gtcatgtgag
     3961 cgttagctcg tgtgggttcg agtcccatca tctgcactac aactcgtgaa gttaattttg
     4021 cttcacgagt ttttttgttt gaacgtttct ttatgccatt atatacatat cactgtatcc
     4081 tttacaaaaa gaacgtacaa tcatgtaaac agcctgaggt gagtatatga aggtcggaaa
     4141 caagctactc gtagaaactt gcaagtgtta aaacaattaa tcgaaaaacg agtaaaatcc
     4201 ctcacctaat actaaagcga gggatttttt gtatattatc tgtttatcac cgttattata
     4261 aaggtacaaa taccaagcac ggttaatcca aattgcataa attcattttt ttgtacactc
     4321 atgcttttca ttagctcttt aactgccatt agtactaaga tggcgataac aacataaagt
     4381 atatagtacg tccgcattcc ggaagcccat actgtgggag aaaatcccat aattaacctt
     4441 gaacaaaatc ccattatcat caaaataact aaaaaaatag aagttttctt attgtcaaaa
     4501 cttaaataaa ttccaacaat taaacatagt aataatgcca agactactaa agtagctatc
     4561 caagtacctg gataaaaaag tgacagtttc gttcctaact ctgtaaagag attattcagg
     4621 ttactactac tccaaatcat tgccctttta tttccattga cgtaagtaaa gctttgaccc
     4681 attgtattac caaaataaat aatcaggttt aagaaaaacg gtaatgcagt caatatacgc
     4741 acataatagt tttgacattt cctatatgtt agaaggaaaa ttaagaaaaa tagcaataaa
     4801 aataagatat tcatgtctaa aaa
//
LOCUS       DAJSMK010000129         4717 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.138, whole genome shotgun sequence.
ACCESSION   DAJSMK010000129 DAJSMK010000000
VERSION     DAJSMK010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.138"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(101..391)
                     /locus_tag="ON488_002482"
     CDS             complement(101..391)
                     /locus_tag="ON488_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HCR3232618.1"
                     /translation="MSINTFVYSHPINVYIIKNLGITVEQFCELYAYPQGTVASWITR
                     QRRIKSLPASFVYDLSLASSLNMSDVYEKLLSLEKEYDSFKIKHDKKIKKHI"
     gene            complement(527..706)
                     /locus_tag="ON488_002483"
     CDS             complement(527..706)
                     /locus_tag="ON488_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232619.1"
                     /translation="MNIIQQYELKYITFDQLSEEIWGYGQRLINEVGVERFSFYVEAA
                     AGYHNFRFYIFPLYI"
     gene            complement(703..1053)
                     /locus_tag="ON488_002484"
     CDS             complement(703..1053)
                     /locus_tag="ON488_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232620.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIIGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(1046..2371)
                     /locus_tag="ON488_002485"
     CDS             complement(1046..2371)
                     /locus_tag="ON488_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HCR3232621.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGNGGIKND"
     gene            2821..3435
                     /locus_tag="ON488_002486"
     CDS             2821..3435
                     /locus_tag="ON488_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232622.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(3600..4604)
                     /locus_tag="ON488_002487"
     CDS             complement(3600..4604)
                     /locus_tag="ON488_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232623.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFYSKEKLADFSNIAEMIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLE
                     LKTLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITA
                     CEIGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEK
                     RNKLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNK
                     SQITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD
                     "
BASE COUNT         1469 a          882 c          703 g         1663 t
ORIGIN      
        1 tactaataat tcccttctta tagtgcattt tcttagaaaa aaacaatatt acgatatcat
       61 gatattaaga tatcgtaata ttatacaatt gtgattgata ttatatatgt ttttttattt
      121 ttttatcatg tttaatcttg aaggaatcat attctttttc taaagacagg agcttttcat
      181 aaacatcaga catgtttaaa ctagaggcca ggcttaaatc ataaacgaat gaagcaggta
      241 atgattttat tctacgttgt cgggttatcc agcttgcaac cgttccttgt gggtaggcat
      301 ataactcaca aaattgttct acagtgattc ctaaattctt gataatgtaa acattgatcg
      361 ggtgcgagta aacaaatgta ttgatagaca tggtgcgtaa gcctactttc ttttattatt
      421 gcgtttgcaa taatagttta acacacgcat tattctagta tctactccta tttgtaaaaa
      481 caaaaaagga ttcatagaga taactctata gaatccgtaa aataccttat atatataacg
      541 ggaagatata aaacctaaaa ttatgataac ctgctgcagc ttctacatag aaagagaagc
      601 gctcaacacc aacctcattt atcaaacgtt ggccataacc ccaaatctct tctgatagct
      661 gatcaaaggt tatatacttt agctcatatt gctggataat gttcattcta atcgactcca
      721 tttattatcc tggtaaaatt cgatatgacg tatttcgtcg tagtgaattt tgtcttttcc
      781 aacgtagatc cccagctcat cactacctaa gatcttgcca atgatatctt ctggatagta
      841 tccttcagcg tttcgttctt ctttttgaat agatactgat ctatttttta tgactgcagc
      901 gttcaatact tccgcaatct cttcagtcgt catttgttct tttgctaaat tttgactggt
      961 tcgttgttca ttgtcggcat caatttcttc agtatgatca gataaataaa accctgccca
     1021 ctttaaacgt ccacgatcat tgtaatcaat catttttaat tcccccattt ccgcccgcat
     1081 gaccaccaac aagtgtgctt ctagtaatgc ttctagcgcc ttctaacatt gaagaagcat
     1141 gtacaatcga cgtaaaacca tatttttgcc gaatcttgtc aataatttta tctaaatttt
     1201 cttcgtcaat ttgcttttgt ggatcactaa ataaatccag ctgaagcgaa tcggtgtaca
     1261 caagcttgct ataggttatt ccaacatgcc ttacttcttg tccttcataa tacttatcaa
     1321 acaagaaaag acaataattc tgcaattcct ttgtattatc tgtgataggg atcttcatct
     1381 ggtgtgaaaa ccctggtctc gtttctaaga tcgacgtgcc aatgtgtaaa tggacacaac
     1441 ctgttttaca gttatgctgc ctaatgcgta tcgctacttg ttccgccatt tcttttacca
     1501 ccagctcgat ttcatttctt ctagtataat ctcgtggtaa cacttgtgaa tttccatatg
     1561 atttttcctt tgtcggttct ggtgggattg ctatatctgt tcgatcgatc ccattagcat
     1621 ggaagtacag ctgtaagcca atcacaccta gtctattctt aatcgtataa ggattccagt
     1681 tagcaagatc tctaatgctc ataatcccca tctgattgag tctttttttc attcgagagc
     1741 caattcccca aaagtccgtc atttcaggaa tattccatac tttttcagga acgttttcgt
     1801 acgtccattc cgcaacaaat ccttcattat gctttgcttc gttgtctaag gctagtttag
     1861 ccaaaagggg attatctccg acacctactg tagcaatcaa tcctagctct tctttaatat
     1921 tctcctggat catttgagcc agcttctttc tccgttgact tcgtgttcct tcagtcgtaa
     1981 aaagattcag tgatcgggtc acttttaaga ttgattcatc gatcgagtaa atcagtagat
     2041 cttcatcagc cacatatctt ctgaaaatat tatttacctg catatttcgc ttgatatata
     2101 ggttcatacg tggtggaaca acgtgtagtg ttttaggaaa tggttgtggt aagtcacgtg
     2161 gtctactcac atttgtaata ccataccgct tttttgcttc aggagaagaa gctaatatca
     2221 atcctgaacc agtattatca gctcgactca taacaacaag ttctgttgtt aatggatcta
     2281 aatttctttc tatacattcg acacttgcgt aaaagctttt catatcgatt aaaaagtaat
     2341 catttactgg ctcttttgaa taatccatca taaataacac tccattcttt cacattatac
     2401 aaacatatgt tcgatattgt aaagaagaaa tagctaaata cataaaaaaa gaagcatagg
     2461 tatgctatca ccctgcttct tcttttgatt tgtatgatca atttattcta tcactttact
     2521 aattaatttg aaaatctaat aaaaactctc actctaaaag agtgagagac tgcaaattag
     2581 agtacggact tttttggagt tccgttcttt aatattaaca aatgaataaa atccttacaa
     2641 catttgagaa taagttatca gtagacactt acaaaaaatt ctcatactat ttcctccatc
     2701 attagttttt gtctatataa ggtttaccct aaatagacac tggtataaca ttgaaaaata
     2761 tggcttcctc gtgtatgatt agagtgtatt ttaaatagtt gcagaaagta ggtaaaagtt
     2821 ttgagagttg catacatacg tgtctcatcg atcgatcaaa atgaacaacg ccagattgaa
     2881 gaaatgaaaa aattcggtgc agagagaatt ttcatcgaga aacaatctgg cgcaacgatt
     2941 actcatcgac ctgttttcca agaagcatta gattacgtcc gagatcaaga tatttttatt
     3001 gtggaagcta ttgatcgact tggaagaaat tatgacgaga tcatcgcttc agtcaattac
     3061 ttgaagaaga aaaatgtgaa gctgatcatt actagtttac cgatcatggc tgaagcaatt
     3121 ggcaatcctc tcctggataa attcattaag gatctgatca tccaaatttt ggccatgatc
     3181 gctgaacaag aacggactga atcgaaacgt cgccaggcac aaggaattaa gatcgcaaaa
     3241 gcaaacggcg tctacaaagg gcggcccaaa ttatacagtg cagacgcaaa agatccccaa
     3301 cgtcgccttg tttacaaaag catcgttgaa gatcttaaaa atggtgttgc gattgctaag
     3361 attgctaaag actacaatgt tacgagacaa accgtgtata gaataaaaaa agacagcatg
     3421 gtcaatgaca aatagttgat catgctgctt ttattatctt ctcatcttta atttcctaca
     3481 tataattact atctataaaa ttaagtctta ctcagaacag ataaagcata aaattccaac
     3541 aaaccatttt ttacttaact aaataaagag tctgttaata taatcttcac ttatttacgt
     3601 taatccccta ctgtatttgt tggttcctta tctatatttt ctacaaaatc cttattatct
     3661 tgtgatttag cttcgtataa ttctttgtat gtcgacacat tggttatact aattcctata
     3721 gctagttctt gagactctac ttttctctct agctcctttg acaaagtgat ttgagattta
     3781 tttggttccg ttggagtcaa ttctatagat tcttcataaa aatctctata cataaagcta
     3841 tcattaattt tataaaaaaa attaaatgtt tttagcactg ccatataaca ttcaaaacat
     3901 tcttctatag ttggtttact tccttgagga gaatgaacca atttattacg tttttctatg
     3961 aaatttttaa tttcctttct tatttctttc ggaaactcaa tattaaagta ccctttaaac
     4021 atgctcccta ataatttgtc tacaggggga gattgtaaat tctcaaatat tagagttaaa
     4081 tcaggtttct cttgttgata aaattccttt acccctattt cacaggctgt aattatcgaa
     4141 ataaacctat ctctagtatt tgatatattt ttacttcttt taaggagtat aagagaaaag
     4201 gggatacttt cgtgtccatg catgtaatta actaattgtt gagcttcaga agttatatct
     4261 ctaattatat agttaacgga attaggaagt gtctttaact ctaatgaaat ttctatccaa
     4321 ttactatctt ctaatctgta tatgctcgaa gtataatttg attcgtcagc aagcatcgct
     4381 acatcccaaa cactgatcat aaaatctttt aaacgttcaa tcatttcagc aatattgcta
     4441 aaatcagcta atttttcttt agaataaaaa aaaacattta tatcagaatc aataaattct
     4501 atttttttta ttactatatc gtcatcatta tcttgaccat ttatgtttat tgttccctga
     4561 gtggggagta cttctttcaa attcaagtta aatttatatt ccattacttc tcctccagtc
     4621 aagtccagac tcctgtgtaa aatgctatac aatgttttta ccatttctac ttatcaaaat
     4681 tgatgtattt tcttgaagaa taaatccatt catcatg
//
LOCUS       DAJSMK010000130         4701 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.139, whole genome shotgun sequence.
ACCESSION   DAJSMK010000130 DAJSMK010000000
VERSION     DAJSMK010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.139"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..190)
                     /locus_tag="ON488_002488"
     CDS             complement(<1..190)
                     /locus_tag="ON488_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232624.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(200..1015)
                     /locus_tag="ON488_002489"
     CDS             complement(200..1015)
                     /locus_tag="ON488_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HCR3232625.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1277..1720)
                     /locus_tag="ON488_002490"
     CDS             complement(1277..1720)
                     /locus_tag="ON488_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HCR3232626.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1854..2192)
                     /locus_tag="ON488_002491"
     CDS             complement(1854..2192)
                     /locus_tag="ON488_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR3232627.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2180..2557)
                     /locus_tag="ON488_002492"
     CDS             complement(2180..2557)
                     /locus_tag="ON488_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HCR3232628.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2781..3974
                     /locus_tag="ON488_002493"
     CDS             2781..3974
                     /locus_tag="ON488_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3232629.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4140..4562)
                     /locus_tag="ON488_002494"
     CDS             complement(4140..4562)
                     /locus_tag="ON488_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232630.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
BASE COUNT         1372 a          896 c          823 g         1610 t
ORIGIN      
        1 tgcaacctgg accaataaaa agtaaagaaa aaataaagga aaagacattc cttccatcta
       61 tcgacaaaag gaacgcagct gctatataca agatattgac acaccaaaaa caaaggctac
      121 ttgccaatga ttgatacaac caataaaaga attccatata aacatttttg tcaaaacgct
      181 gctctttcat aatcacctcc tattccttca ttcctgatga agcgatccct tctacaaaat
      241 atttttgcat cgctaaaaat ataaaagcaa caggaagaac agaaacaact gaggcagcca
      301 tgattaatgc gtactctgca tcaaatagcc caataaacat tttcaaccct aactggattg
      361 ttttattttc cgtagaagac aaataaatga atggccccat ataatcgttc catgtattaa
      421 cgaatgtgat gatcgtcaaa ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc
      481 gatagattcc ccactctgat aagccatcga tccgcgcact ctcacataaa gaatctggga
      541 tactactgta gtattgcttc aacaagaaca caccaaaagc attgaacgct tgtaatagca
      601 ccaacgacca caacgtatat gttaaaccca cttttctcat cataatgaac tgcgggatca
      661 tataagactg ccaagggaca gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc
      721 ctttaaaatt tagtttagaa aacccgtaag cagcaaaact agaagtaaac aactgaatca
      781 acgtgatcac aacgcttaaa aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag
      841 accaaataac cagataattc tctaaatgcc aagttttagg gatccattga atcggaatcg
      901 tgaacacttc attatttgct ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg
      961 tcaataaagc taatacaatc agcagaatca tacccaacca ttgaataaag ggcatgtttt
     1021 ttgaacgaat ttttgctttt tttctttcat ttcgaacacc tccaaagtta taatcttcat
     1081 ttctttgtaa tgattacaat ccagaacaac ggttattata gctgattcat ttccgttctt
     1141 cttatgtttg taagcgctta tttaacaagt tatgtaaatc tctttatttt ttttgattta
     1201 aaaatgaaaa aatacaaaag caagactgtc atacgtctcg cttttgtatt gaaatttctt
     1261 cgattagaga tacttattac tgttcaaaag cttctttgaa acggtgaatc aattcattga
     1321 ctacaggtga taaaatccga ttctttttcc agactagcat gcagttcgtt tcaatcattg
     1381 ggtcaagcgg aacgaatgtc actcgctttg aaagatgact tacagcacct tctatgacta
     1441 aagcagcacc tacctgattc tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc
     1501 ctgtgatcag caactgctcc ttttttatgc ctaaccagtc agcaaacatt cgctgtattt
     1561 ctggacgctt tgagatcaaa agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt
     1621 tttttgctaa aacagaattt tctaaaatga gcaatcccca tttttccttt cttggtaaca
     1681 aaatcgtttc gtatttctct gtatctactg gatctagcaa aatcgctaaa tctaacaggc
     1741 ttttttctag tcactccgtg atatcatcac ttgttccgct gtggatatga aattgaacgc
     1801 tgggataatc acggatcaac ttttctagta atagtgccaa tgtattcgaa ttatcagctt
     1861 ccacacagcc gatcgtaaat cggccgctga ataattgttt ttttctgttc tcgaattctt
     1921 gagtggtttg attcgttaaa tctaaaattt cttctgctcg gcttttttag aaaataacct
     1981 gcttctgtca agatcatttt gcggttttcg cgtacaaaca gttctgttcc tagttcctct
     2041 tctaactcct tcagttgtcg gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct
     2101 tgagagattg ttccttcttc tgcaattgtc caaaaatatt ttagtaagcg taactccata
     2161 gcgatgctcc ttgatttttt tacttgatac attccatttt atttctagat aacacacgat
     2221 catatttctt gatttttcct tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt
     2281 tcgtcaaaag ttcactttct tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc
     2341 cttcgctaga taggcgaata tattcaatca aagactcgat cgataatccg gcatttcgca
     2401 tacagatcgt aaagtcgacc cattttaggt cttcttctgt ataatcacgg attccgcctt
     2461 ttgtccgatt aactggtgga atcaacccga ttcgttcata atagcgcaat gtatcggccg
     2521 aaatgccctt ttcttcactg acttgtttga tattcatctg atcactcttt ctcttaattt
     2581 cttgccactt tacttatgta ttttatttat tctacaactt taagtgtact ccaagtcaat
     2641 actcatttct attaaaacta agctggatta tctatatcgg ttgtttgtgt attatttcaa
     2701 ataaaaaagt cttgtttttt tattcttttt tggatatact tttaacaatt tagggaaatt
     2761 ttaggaaaag gggtataaaa atgacaacgt atcagcgaaa ggtattatta tcgacatcgg
     2821 cgggaattgc tttagagaat atggatatta tgtttttagc tttttcatta tcttcaatga
     2881 ttacttcttt tcatattagt ggtacgcaag cgggtttcat ttcaacgatc actaatttgg
     2941 ggatgctcat tggaggtatt ttttttggca tcatagctga taaatatgga cgtgtgaaag
     3001 tattttctca aacggtcctt ctgttttcga ttgcttcttt attgatgtat tttgcttcaa
     3061 acatctactt ggtttatctc tttcgcttta tcgcaggtgt aggagcggga ggagaatacg
     3121 gggcgtgtat gtccttgatt tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt
     3181 cggttgctgg tattggtgcg caggtcggtg cggctttggc tgcgatttta gctgctgtga
     3241 tcattccaac gtttggttgg aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg
     3301 tcttgttcat tcgtcgcggc ttgactgaac caaaggaatt caaatctgta caatctgccg
     3361 aaaagaaaac caaacttagc agactgtttg aatcaaaaca tcttgcttgg caaacatgtg
     3421 gccttagtat catggtaact gtccaaattg ccggctattt tgggttaatg aattggctgc
     3481 cttcaattat gcaaaatcga ttagggcttt cggtttctgg gtcttcattg tggatggtca
     3541 gtactatttt aggcatgtct ttggggatga tgacttttgg cataatcatg gataaattgg
     3601 ggcctaaact agccttttct ttgtttttaa tttgttcatc cttatctgtc tatctacttg
     3661 tgttagccca tagccagtgg agtttggtag cagccgctgt gatagtcggc tactttatca
     3721 atggcatgta tggtggatat ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg
     3781 cgacggcgaa taatttcatt atgaaccttg gacgagctgt tggtggtttt tcttctatcg
     3841 tcatcggttt cttgatggat cattatagtt taactgccgt aatcttgttt ttgagcggta
     3901 tttacctagt cagtctgctg gtcttgacaa ctcttactgg tgttacagca ttaagggaaa
     3961 gcttgcagca ttgatagttg agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc
     4021 atctgcggta ataagaccag ccaaatcaaa aacatgagac actgtttccg tttggctggt
     4081 cgtattactt gatgcagggc agctttttca actgctaatt tccttctatc tggcggcgac
     4141 tattctttga cgtccgtcat ttcaaagtac tttactaata acttagcata acgaaaaact
     4201 gtggatacac tcgtatattg agcgtctgca taatcttcca aatttttctc aggatgttga
     4261 tacatgaatt caatcaaatg ataattatat gattttctgt agaaatgaag ataaataatg
     4321 tagattggga agttctcctg cttttccata gaaaagcgcc gattattctc attcttcaaa
     4381 atgaccttat caggatattt ttggaacaat tcttctaaat ctgttagata attcaagata
     4441 gacttacttg ataccttcaa ttcgttttgt agttcttcta ttgaacacca acgttctgtt
     4501 tcaagcagta aatgaatcat tttaattttc ttttgagaaa cttttgttaa aaaagtctgc
     4561 atattttctc ctcctgtatc tactttacta tactacatac aagaaaaaaa acggatacaa
     4621 atatcatatt gtcacaccgt caatagtgca taaacctgtt attatttctc tttttttcct
     4681 aagtattcta ttgatatgaa t
//
LOCUS       DAJSMK010000131         4674 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.140, whole genome shotgun sequence.
ACCESSION   DAJSMK010000131 DAJSMK010000000
VERSION     DAJSMK010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4674)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4674)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4674
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.140"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            131..796
                     /locus_tag="ON488_002495"
                     /pseudo
     CDS             131..796
                     /locus_tag="ON488_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            832..1077
                     /locus_tag="ON488_002496"
     CDS             832..1077
                     /locus_tag="ON488_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCR3232631.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1180..2049
                     /locus_tag="ON488_002497"
     CDS             1180..2049
                     /locus_tag="ON488_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HCR3232632.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2030..2764
                     /locus_tag="ON488_002498"
     CDS             2030..2764
                     /locus_tag="ON488_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3232633.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2797..3705
                     /gene="ant(6)"
                     /locus_tag="ON488_002499"
     CDS             2797..3705
                     /gene="ant(6)"
                     /locus_tag="ON488_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HCR3232634.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKGGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3702..4244
                     /gene="sat4"
                     /locus_tag="ON488_002500"
     CDS             3702..4244
                     /gene="sat4"
                     /locus_tag="ON488_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HCR3232635.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4337..>4674
                     /locus_tag="ON488_002501"
     CDS             4337..>4674
                     /locus_tag="ON488_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(3') family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HCR3232636.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKII"
BASE COUNT         1630 a          675 c         1014 g         1355 t
ORIGIN      
        1 gaaaaataga ggtctttcca tttagatagt agtggaaaga cctctattta tcttttgaaa
       61 gtgaatacaa aaataaagca cactctgcta taatataggt gattaatcca tttgagagag
      121 gtgctttatc atgtatcaaa attataccat aaaccaactt tgtttgccta tagatcttga
      181 aattaaatta gaagaaaatg attttgctca tgccattgtg cagtttgttg actctattcc
      241 cgatgaagtc tttcttcctt attatcaatc tatgggtaga ccccaatatc atcctcgtat
      301 gctactttcc attattcttt gtgcctatat tcaaggggtt tattcgggcc gccaaataca
      361 aaatatgctg atagatagta ttcggatgcg ctacttatct caagagcaat tccctaactt
      421 tcgtactatt aatcgttttc gcgttcatcc gattatgaac gatattctag atcattcatt
      481 tgttcaattt cgtgagctac tggttcaaag tggcttaatc agtggcagtg ctctatacat
      541 tgatggtaca aaaattgaag cggatgcgaa taaatactct ttcgtttgga aaaaaagtat
      601 tttaaagtat aaggatagcc ttgatcaaaa agcccttgaa aactaccaac aaatggtgga
      661 aacaaaaatc ttacctgagt taatagatga tttaaaggat gaactttcta tagaagagat
      721 tgaaaggatt cgtcaatctt tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca
      781 aaccgaaaca gtagaagggg gctgacccat tattaataag gagtggacaa catgattgat
      841 gtaaatgagc tattggaaga agctattaga gaaactgaaa atctaaatga tggcgaagtt
      901 tttcttgtta aagatttatt caagggatat gtggggaata ggatacccag aaaggatcga
      961 cttctgcttg gaacgttatt tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct
     1021 attgaaaaga cttcatctaa tcagcagagg tataaaaaga caattgataa gttttaacta
     1081 tcttttgtga aattaaaaaa attataaata tgttgagtag aagcaaaaga tttggcttgg
     1141 aatttttaca gcagtgaatc gataaaagga gcatgcttga tggtagataa tattattaaa
     1201 tcagtagcag agaaattatc ctctctgtct tatatagaag gtattgtttt aggtggttca
     1261 cgtgcaaggg gcacccatac agaggattcg gatatagata tcggcatcta ttacaattca
     1321 gaatcatttg acataaatac tattaatcaa ttcgctacaa agctggatga tgagcataga
     1381 aataaccttg ttgtacctcc cggagcatgg ggtgattgga ttaatggcgg cggatggtta
     1441 gtcataaacg ggtatcatgt ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata
     1501 atgaaagata cagagcacgg aattgttact gccaattatc agactgggca tccccatggt
     1561 tatattagtg caatgtatcg aggagaatta gcgattagca aaatactata tgctaagaat
     1621 gaaagcttat gcgaattaaa aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt
     1681 ttagttaact tttttatgtt tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg
     1741 ggaacagacg ataaatatta tattgcgggt catgtttttc gtatagtttc atgtttaaat
     1801 caagtgttat ttgcatgtaa taatgcttat tgtatcaacg aaaagaaagc tataaaactg
     1861 cttgaaactt ttgaacataa acctgaaaaa tataccgaga aggtaaatca tatttttgaa
     1921 gtactcggta tctcactttt tgaatgctac gacatgaccg agaagcttta taatgaagtg
     1981 aatgaaattg tatcggagat aaataacttt ttaaacgagg agagttcaga tgaaagaaaa
     2041 caaatatgat gataatatat tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg
     2101 actggctggt gcgggagaat gggagacttt gaaaaagatg ctacctgatt ttaagggtaa
     2161 gcgtgtgctt gatttaggat gcggctatgg atggcactgt atatatgcga tggaaaacgg
     2221 tgcttcctct gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa
     2281 aacccatttt ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga
     2341 ggagagcttt gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa
     2401 tttaataaaa aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga
     2461 acatcctgtt tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat
     2521 actgcatttc ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga
     2581 agaaaaggtt acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa
     2641 tagttttata ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc
     2701 ggggatggcg gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat
     2761 gtaataatat agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg
     2821 gatttagtac tttctttagc agaacaggat gaacgtattc gaattgtgac ccttgagggg
     2881 tcacgcgcaa atattaatat acctaaagat gaatttcagg attatgatat tacatatttt
     2941 gtaagtgata tagaaccgtt tatatctaat gatgactggc ttaatcaatt tgggaatata
     3001 ataatgatgc aaaagccgga ggatatggaa ttattcccac ctgaagaaaa gggattttcc
     3061 tatcttatgc tatttgatga ttacaataaa attgatctta ccttattgcc cttggaagag
     3121 ttagataatt acctaaaggg cgataaatta ataaaggttc taattgataa agattgtaga
     3181 attaaaaggg acatagttcc gactgatata gattatcatg taagaaagcc aagcgcaagg
     3241 gagtatgatg attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg
     3301 tgccgtaagg aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg
     3361 ctgagaatga tatcatggaa gggcggcatc gaaacaggct ttaaattaag tgtaggcaag
     3421 aactataagt ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc
     3481 taccggatgg attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc
     3541 agggcggtat ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg
     3601 aatataacaa aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg
     3661 gatagcacat atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag
     3721 cagggcacct gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta
     3781 taccgaggta tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt
     3841 taaaaagcta ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata
     3901 ttgacaatac tgataagata atatatcttt actaccaaga cgataaatgc gtcggaaaag
     3961 ttaaactgcg aaaaaattgg aaccggtacg cttatataga agatatcgcc gtatgtaagg
     4021 atttcagggg gcaaggcata ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc
     4081 ataaaaactt gcatggacta atgcttgaaa cccaggacaa taaccttata gcttgtaaat
     4141 tctatcataa ttgtggtttc aaaatcggct ccgtcgatac tatgttatac gccaactttg
     4201 aaaacaactt tgaaaaagct gttttctggt atttaaggtt ttagaatgca aggaacagtg
     4261 aattggagtt cgtcttgtta taattagctt cttggggtat ctttaaatac tgtagaaaag
     4321 aggaaggaaa taataaatgg ctaaaatgag aatatcaccg gaattgaaaa aactgatcga
     4381 aaaataccgc tgcgtaaaag atacggaagg aatgtctcct gctaaggtat ataagctggt
     4441 gggagaaaat gaaaacctat atttaaaaat gacggacagc cggtataaag ggaccaccta
     4501 tgatgtggaa cgggaaaagg acatgatgct atggctggaa ggaaagctgc ctgttccaaa
     4561 ggtcctgcac tttgaacggc atgatggctg gagcaatctg ctcatgagtg aggccgatgg
     4621 cgtcctttgc tcggaagagt atgaagatga acaaagccct gaaaagatta tcga
//
LOCUS       DAJSMK010000132         4434 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.141, whole genome shotgun sequence.
ACCESSION   DAJSMK010000132 DAJSMK010000000
VERSION     DAJSMK010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.141"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(543..2048)
                     /locus_tag="ON488_002502"
     CDS             complement(543..2048)
                     /locus_tag="ON488_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HCR3232637.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="ON488_002503"
     CDS             complement(2045..2731)
                     /locus_tag="ON488_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HCR3232638.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ON488_002504"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="ON488_002504"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HCR3232639.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1547 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attt
//
LOCUS       DAJSMK010000133         4425 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.142, whole genome shotgun sequence.
ACCESSION   DAJSMK010000133 DAJSMK010000000
VERSION     DAJSMK010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.142"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            690..1658
                     /locus_tag="ON488_002505"
     CDS             690..1658
                     /locus_tag="ON488_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HCR3232640.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="ON488_002506"
     CDS             1669..2484
                     /locus_tag="ON488_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HCR3232641.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="ON488_002507"
     CDS             2552..3262
                     /locus_tag="ON488_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HCR3232642.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="ON488_002508"
     CDS             3298..>4425
                     /locus_tag="ON488_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCR3232643.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1490 a          661 c          921 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DAJSMK010000134         4359 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.143, whole genome shotgun sequence.
ACCESSION   DAJSMK010000134 DAJSMK010000000
VERSION     DAJSMK010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4359
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.143"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            11..241
                     /locus_tag="ON488_002509"
     CDS             11..241
                     /locus_tag="ON488_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HCR3232644.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            338..1639
                     /gene="murA"
                     /locus_tag="ON488_002510"
     CDS             338..1639
                     /gene="murA"
                     /locus_tag="ON488_002510"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HCR3232645.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1652..1828
                     /locus_tag="ON488_002511"
     CDS             1652..1828
                     /locus_tag="ON488_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HCR3232646.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            1963..2259
                     /gene="yidD"
                     /locus_tag="ON488_002512"
     CDS             1963..2259
                     /gene="yidD"
                     /locus_tag="ON488_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HCR3232647.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2323..2706
                     /locus_tag="ON488_002513"
     CDS             2323..2706
                     /locus_tag="ON488_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232648.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            2875..3759
                     /locus_tag="ON488_002514"
     CDS             2875..3759
                     /locus_tag="ON488_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HCR3232649.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            3873..4109
                     /locus_tag="ON488_002515"
     CDS             3873..4109
                     /locus_tag="ON488_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HCR3232650.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4197..4277
                     /locus_tag="ON488_002516"
     tRNA            4197..4277
                     /locus_tag="ON488_002516"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4231..4233,aa:Tyr,seq:gta)
     gene            4284..4355
                     /locus_tag="ON488_002517"
     tRNA            4284..4355
                     /locus_tag="ON488_002517"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4316..4318,aa:Gln,seq:ttg)
BASE COUNT         1474 a          685 c          976 g         1224 t
ORIGIN      
        1 ggacgtcatt atgcaagtat acggaattga tgcggtgctt cgaatcgtga gtcatttggc
       61 gtttatctac ttagccttct ggtctttacg ttcgttacgc attgaaactt ttttcagacc
      121 aatgcataat acgcaaatta gaatggcaat cgtacttttt tcaatttttt tagggtacac
      181 tgcaagtaat tttttcttag aagttatcgc tttatgccga aatcttttcg ttagcctgta
      241 aattttaaaa aaaggtacta ttttaaaagc aaggatgtta taatagaaaa gattttgagt
      301 aagtgtatgc tcattggaat tttttggagg gaacaacatg gaagagatca tcgtaagagg
      361 tggcaatcaa ttaaatggaa cagtaagaat tgaaggagct aaaaatgctg ttttgcctat
      421 tttagctgct agtttgttag cagaagaagg tattacgaca ttagacaacg ttccgattct
      481 ttctgatgtc ttcactatga atcaagtgat tcgtcactta aacgtagatg tagattttga
      541 tgaacaaaag aatcaagtaa caatcgacgc ttcaagacaa ttagaaatcg aagcgcctta
      601 tgagtatgtt agtcaaatgc gtgcttcaat cgttgtgatg ggtccgctac ttgccagaaa
      661 tggacatgca aaagtagcta tgcctggtgg atgtgcgatt ggtaaacgac caatcgattt
      721 gcatttaaaa ggatttcaag ctttaggagc aaaaattatt caaaaaaacg gctatatcga
      781 agcaattgcg gatgaattga tcggtaacac gatttattta gatttcccta gtgtgggtgc
      841 tactcaaaat atcatgatgg ctgccgtaaa agcaaaagga acaaccatca ttgaaaacgt
      901 agctcgcgaa ccagaaatcg ttgatttagc aaacattttg aataaaatgg gcgctcaagt
      961 ctatggagct ggtactgaaa caatgcgtat tgaaggcgtg gatcatttac atgcagtcaa
     1021 ccactcaatc gtacaagatc gtatcgaagc aggtaccttt atggttgctg ctgcaatgac
     1081 acaaggcaat gtgctgattg cagatgctat ctctgaacat aactgcccat tgatttctaa
     1141 attgatcgaa atgggtgcag aaatcattga agaagaaggc ggagtccgtg tcatcggacc
     1201 aaaacatatc ttacctacag atgtaaaaac gatgcctcat cctggtttcc ctacagatat
     1261 gcaagctcaa atgacagcta tccaattagt tgcagaaggt acaagtgtgg tgactgaaac
     1321 agtgtttgaa aatcgtttcc aacatttaga agagatgcgc cgtatgaacg ctcatgtcaa
     1381 aatcgacgga aatgtagcaa tcatggatgg aaaccatgaa ttgcaaggtg cagaagtata
     1441 tgcaacagac ttgcgggcag cagcagcatt agttttagct ggcttgaaag caaatggaat
     1501 cacacgtgtg cgtaacttga attatctaga ccgtggatat tataatttcc atatcaaact
     1561 acagcaatta ggtgcagacg tcgaacgtgt agacatggat caaacttctg ctgaaaaaac
     1621 agcacaaacg attgcttaag gaagtggctg aatgagtaac caacgatata tcttattaac
     1681 tttgataaag attttagtgg tgatcttatt gcttatcctt ctttttgtgg ccggaacgat
     1741 gatcggatat ggtgtcatcg gtggcggcaa tccatttaaa gtattccagc caagtttgtg
     1801 gattcatatt cgagactttt ttcattgata aataagaatc acagtggttc tagtcgatat
     1861 gaagtgagcc atgaagcaga acatgataaa agaaaacaga agggaacgtt gacgttagtc
     1921 gcgatccctt tttttagtaa aagaaaagaa ggaatctaat tgatgaagaa gatattgatt
     1981 tatttagtta gaggatatca gcgctttatt tcgcctgcat ttccacctag ctgccgttat
     2041 tacccaacct gttccaatta tatgataaaa gcaattcaaa cccatggtgc gctaaaaggg
     2101 acggtaatgg ggactgcacg gatcttacgc tgtcatcctt ttgtcaaagg cggtatcgat
     2161 tatgtaccat tgacattccg attaacgcga aataagaaag ataaaaaaga accagattat
     2221 aaaaaggttg tgaaaaatac gggtagcact gagcgataaa gaaaaagagg aaatttattg
     2281 tcaaagtaac aactccgcaa ctacttatat gggggacaaa aaatgatcga agaactaaac
     2341 aagaaagatt taccatggtc cttgttatta gatgcagatc ctgataaaga aaaagttcaa
     2401 gtatatgttt ccagagggag tggctggata tggaaagaaa aagaaaaaac aataggtgta
     2461 ctgatctatg tggcaaggga aaaagaatac gaaatcgtca atgtagcagt aaccccaacg
     2521 tatcaaggaa aggggattgg cggaaaatta cttgagacag cttttcagaa gctttcacag
     2581 ctagcttcaa accaaactcg gatcattata cgtactggca ctactagtag cgctgcgtta
     2641 cacctctatc aaaaaatggg ctatgtggag attggtcgag tcaaagacta ttttatccat
     2701 cattaatctg agcccatttt tgaaaatgga gatcaattaa gggatcaagt gattttagca
     2761 attcacttac ctaaaaatag ctttaactaa taaactttca attcgagaaa atgctttcaa
     2821 atgctaaata gatacattac aatagcttta gcaaacaaaa aggagaatat ttttatggga
     2881 atattagttt ttgattttgg tggatcggct gtcaaatatg gttgttggga tggcaaagag
     2941 attaaaggta agggacaatt tgcaacgcct gaatcttggg aagaaatgaa aacgcaatta
     3001 tttcaagttt ataaaaaaat actcgtttct tttgaagtcg aaggaattgg aatcagctct
     3061 cctggagtag tgaataatga gaaacaggtg attgagggaa tcagtgcgat tccttatatt
     3121 catggattta atattttccg agatttggaa actctgtttc aactcccagt aacgattgaa
     3181 aatgacgcca actgtgccgg aatggctgaa ttttatgaag gtgctgcccg tgattatcaa
     3241 gatgttgctt ttgttgtggc aggaactggg attggcgggg cgttgttcac gaaaggacaa
     3301 ataaataaag gggcacatct ttacggtgga gaatttgggt tgatgttctt agatggcgat
     3361 aagacattca gtaaacttgg tacagcggta cagatggctt ggcgttattg tgaacgcaaa
     3421 ggtctcgata aaaatgctta taccggaaaa gatgtctttg aattagcaga aactggagat
     3481 gcaatagcaa aagaagaagt tgagagtttt tatacgtatc ttacaaaggg attattcagt
     3541 attcaatttt cgtttgatcc agaagtgatc gtattaggcg gcggggtttc tgcaaaagaa
     3601 gggctcattg atgagatcaa aagccgaatg aagaagctga cagaacaatt cgatctgcat
     3661 gatttcgaac cgcagatttt attatgtgag tacagaaacg atgctaatct tgtaggtgca
     3721 gcagcaaact atctcgctgt acgtcaagga gagaattaag agctttagag aaggtgcagc
     3781 ttgcataaaa gaagagaatg aaatgaatag gagattttta cctaaggaat gttttatttg
     3841 ctgcagtatg ataaaatatc tgagaggtga aaatgatgtc aaaaaaaaat aaagatattg
     3901 aagtgcgtat agaagaagtg aaaaaagata tcaaaggtaa gaattatgaa gtcactcagt
     3961 tatttatagg gaaaaaaatg attggtgaga tcttagccta tgggccaaaa gaatatgaaa
     4021 ttttctttgg tgaagaagat tttggaaaag aaaaaagtct tgaaaatgcg atagaaacag
     4081 tgattcgaca ctggaatctg cacgaataaa aaaatatcaa aaaaactttc aataaagggt
     4141 tgcaaaaatc tggaaaatta ggtattataa ctaagtcagg ttgatacaaa cctttcggag
     4201 gagtagcgaa gtggctaaac gcgacggact gtaaatccgt tccttagggt tcagtggttc
     4261 gaatccactc tcctccattt cattggggta tagccaagcg gtaaggcaag ggactttgac
     4321 tccctcatgc gttggttcga atccagctac cccagtata
//
LOCUS       DAJSMK010000135         4352 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.144, whole genome shotgun sequence.
ACCESSION   DAJSMK010000135 DAJSMK010000000
VERSION     DAJSMK010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.144"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(213..443)
                     /locus_tag="ON488_002518"
     CDS             complement(213..443)
                     /locus_tag="ON488_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HCR3232651.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(673..1491)
                     /locus_tag="ON488_002519"
     CDS             complement(673..1491)
                     /locus_tag="ON488_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HCR3232652.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1652..2341
                     /locus_tag="ON488_002520"
     CDS             1652..2341
                     /locus_tag="ON488_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HCR3232653.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2355..3857
                     /locus_tag="ON488_002521"
     CDS             2355..3857
                     /locus_tag="ON488_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3232654.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3870..4346
                     /locus_tag="ON488_002522"
     CDS             3870..4346
                     /locus_tag="ON488_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3232655.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         1452 a          631 c          770 g         1499 t
ORIGIN      
        1 tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat gaactaataa
       61 ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc ataaactttt
      121 aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca taacattgaa
      181 gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt cttataaaca
      241 agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt tatagaaaac
      301 attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc agtaggttcc
      361 tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt atttaagaga
      421 ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta cacgtttttc
      481 tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc aagaaccgta
      541 ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa taagctatca
      601 agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta ggtttagcta
      661 agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt tttctcttaa
      721 ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat cacaaatata
      781 aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa tggctgtttg
      841 taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta tagcaataat
      901 ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg ttttcccaga
      961 taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt gggcttgaaa
     1021 atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat tttctaaatc
     1081 aagactagta tttccactag atcccactcc aaatatatat atgttttttg attgagtgat
     1141 cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg aatagagagc
     1201 ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat gttctttttt
     1261 ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag aaaaaccaat
     1321 tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct taatatcact
     1381 catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga cttttttttc
     1441 agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca tacaaactcc
     1501 tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact cctaaatact
     1561 ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag ttattatcca
     1621 aaaataataa aaaattggag cgtttaggat aatggataaa aagaggtttt tagatcttat
     1681 ttcaaaaggt ttgattgttt catgtcaagc attacctggt gaaccatttt acaaagagga
     1741 agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag ttggtatacg
     1801 tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac caatgattgg
     1861 aattattaaa agagattatc caccagaatc tccattcatt actgccacta tgagagaagt
     1921 agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc ttagaaatcg
     1981 acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat atcctcatca
     2041 gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata aagcaggaat
     2101 agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac aagatgggcc
     2161 agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg ctgagggaag
     2221 gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag gtattgttgt
     2281 gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag cattaagtta
     2341 gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc atgttaccaa
     2401 ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta acaaatgaga
     2461 gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt ttaagtatta
     2521 tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca attggtattg
     2581 ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga gtagcttatc
     2641 tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac
     2701 tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt ttacacaatc
     2761 gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca agatttattc
     2821 cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta atttggccac
     2881 caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt agtttaggaa
     2941 cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac cacaccattt
     3001 accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga tcaacaattg
     3061 ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact ggtctgttta
     3121 cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga ttaccagcag
     3181 catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat ggtgggcttt
     3241 attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt gaatatatgt
     3301 ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga ttatcttttt
     3361 attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt ttgatcgact
     3421 ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa ttaattcctt
     3481 ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc aaaaaattta
     3541 aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa gtaataaaca
     3601 aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt ggaaaagaaa
     3661 atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg aatggggaga
     3721 ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg
     3781 gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc aatcaaatat
     3841 taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag
     3901 aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta aatgatcctg
     3961 tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt
     4021 atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct attaatataa
     4081 aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt gaattacaag
     4141 gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa acctcgttgg
     4201 ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt atagttgttt
     4261 ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt gctcatggga
     4321 attcatgtgg aaaaatcact ttttaaaaaa gt
//
LOCUS       DAJSMK010000136         4350 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.145, whole genome shotgun sequence.
ACCESSION   DAJSMK010000136 DAJSMK010000000
VERSION     DAJSMK010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.145"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(632..1009)
                     /locus_tag="ON488_002523"
     CDS             complement(632..1009)
                     /locus_tag="ON488_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HCR3232656.1"
                     /translation="MKKSYPVIFSAEENGYSVVFPDFAGATQGDNFEEAMSNAKEFLD
                     GILAYYIDEDISVPSPTDIHQLNNLGNNKIVSLIQSDPSPFIQKKTVRKNVTVPEWLV
                     ARGEKDKINFSKVLTDALLKIYE"
     gene            complement(1055..1243)
                     /locus_tag="ON488_002524"
     CDS             complement(1055..1243)
                     /locus_tag="ON488_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HCR3232657.1"
                     /translation="MPLTGKKMLKLAKKNGWKVVRITGSHHIVAKEGFPPVPIPVHSN
                     QDLKKGTEQKLLKDLGLK"
     gene            1414..1977
                     /locus_tag="ON488_002525"
     CDS             1414..1977
                     /locus_tag="ON488_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232658.1"
                     /translation="MKFGGHFLNKKQDQEYYIEKLEKENLELKERIRYYETKFCKRGD
                     CMKPNPVETGKRIKSIRSNFGMTMEQFADLIGNAQKGNINNWERGFSLPNKERLIKIA
                     ELSNKTIDWIKWGTLEEYITSYLIGIGYELYIKDFPEIPHKVFKDIQEKYSDTFSLDK
                     DYELLDSIIKNIFTKYYSKEFEVTQIP"
     gene            1991..2773
                     /locus_tag="ON488_002526"
     CDS             1991..2773
                     /locus_tag="ON488_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232659.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSNTFSLNKDYELLNPIIKNIFTKYYSKDFEDYRDIEVKPDPKKVGRKIRSIRK
                     KLGLTMQEFGYEVSNSPRSTVSTWEHGGNLPNKAKLKKIADIANCSVEDLLFDEGFIS
                     EKSQVKLINELKEENSKLKEKIKYYECLFDGIESLLNSRKNS"
     gene            2813..3424
                     /locus_tag="ON488_002527"
     CDS             2813..3424
                     /locus_tag="ON488_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002362670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232660.1"
                     /translation="MLVGYARVSSDDQNLERQLEEFRKIGVEKVFAEKKSGRNTVERP
                     EFNKMLSFVREGDTLVFESLERLGRNSDEILETVSFIDKNGMGLMVLNLPILDTKFGD
                     PNLEKLVRSLVINIFSWTAQNEREEIKRKQKQGIAIAKKKGVYKGKPYEYSSTAKNPQ
                     KRFIYNEIVRMLGEGVPIKRIAEKTGTNRNLVYRIKKRISESD"
     gene            3868..4017
                     /locus_tag="ON488_002528"
     CDS             3868..4017
                     /locus_tag="ON488_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232661.1"
                     /translation="MKLEIKEVVCDWGIYVDGETYPFMIFNSKANAQEIMRIMELDNK
                     HERFD"
BASE COUNT         1657 a          581 c          809 g         1303 t
ORIGIN      
        1 gcttattatc agttgaaaga acaaataata aataaaggga aaagatatgg aatagaagtt
       61 aaaagtgagt agaataagaa atcgttgatt tggcaacgaa atagtgaggg gacactcact
      121 cactgaaggg ttagctctgt caagttgtgt aaccagacgg aaggacgaat attgttgagg
      181 ttttagaacc atgtaaaaca acacagttct caaatgttac ggataaaccg tttgcgggaa
      241 atcaggtttt aaaaccatgt aaaacaacac agttctcaaa taaggcttta ttgaattgat
      301 cagtagtttc tgttttagag ttatataaaa cgacatggct cttaaatagg agctaacgaa
      361 gaaaaagaag gtactccgtt ttggagttaa gtagaaataa aaaaatagaa tcgttgattt
      421 ggcaacgagt tgaaaaatac gcaaaactat ggtcaccaag ggataaccct gaaactgatg
      481 atcgctatat cttactagta gttaaacagt ctaaatagta ctcatttatt gtattgattc
      541 taagggaacc tgcaataaat gagtactatt ttacttttaa ttccgctatc tatgtcatta
      601 ggcaactaaa ttgttattaa tatatttacg tttactcgta tatttttagt aacgcatctg
      661 tcaaaacttt agaaaaattt attttatctt tttcccctct agctactaac cattctggga
      721 ctgtgacgtt tttgcgtacg gtcttttttt ggataaatgg agaaggatca ctttgaataa
      781 gagaaacaat tttgttattg cccaaattat ttagttgatg aatatctgtt ggagaaggaa
      841 ctgaaatatc ttcatcaata tagtaagcta gaatcccatc aagaaattct ttagcattgg
      901 acatagcttc ttcaaaatta tctccttgtg ttgctccagc aaaatcagga aaaactactg
      961 agtagccatt ttcttcagca gaaaaaatta cagggtaact ttttttcatt tccaccactc
     1021 ctttcgagtt aatccaatga actaaaggac tgggctattt cagccctaag tcctttagta
     1081 acttctgctc tgtccctttt tttaaatcct gattactatg aacaggaata ggaacgggtg
     1141 ggaatccttc tttggctaca atatgatggc tgccagttat cctcaccact ttccaaccat
     1201 ttttcttggc tagtttgagc atttttttac cggtaagtgg cattcgcgac tacctcctta
     1261 caaatattat tatacgcatt atgcgtataa aggtcaagag tttttacatt aaaagtagaa
     1321 tgtaagtgtc acaatagggt ataccctatt gtatcatatg gtaaagtaca gtataataag
     1381 gtttggaggt gtaacactag ggtgtaacac aatgtgaaat ttggaggtca ttttttgaac
     1441 aagaaacagg atcaagaata ttatatagaa aaattggaga aagagaactt agaactcaaa
     1501 gagcgaataa gatactatga aaccaaattc tgtaaaagag gtgattgtat gaaaccaaat
     1561 cctgttgaaa caggtaaaag aattaaatca attcgttcta attttggaat gactatggaa
     1621 caatttgcag atttaattgg aaatgctcaa aaaggaaata ttaataattg ggaacgagga
     1681 ttctcccttc ccaacaaaga aagattaatt aaaattgctg aattaagtaa caaaactatc
     1741 gactggatta aatggggaac tttagaagaa tatataactt cataccttat cggtatagga
     1801 tatgagctat atattaaaga ctttccagag atacctcaca aagtctttaa agacattcaa
     1861 gaaaaatata gtgatacgtt ttcgttagat aaagactatg aattattgga ttctataata
     1921 aaaaatatat ttacaaaata ttactcaaaa gaatttgaag taacccaaat tccataagag
     1981 aggtgattgt atgaagccaa atccttcaga agcaggaaaa cgaatcaaac aattacgcct
     2041 ttcatgtggt tttactatgg aagaacttgg aaggaaaata gataattcac cacgtgcgac
     2101 catatccaac tgggaacgtg ggaccaattt accaaatcca caaaagctga aattattatc
     2161 aactatcact aattcaacaa ttgactggat taaatgggga actttagaag aatatataac
     2221 ttcatacctt atcgatatag ggtatgagct atatattaag gactttccag aaatacctca
     2281 caaagtcttt aaagacattc aagaaagata tagtaatacg ttttcgctaa ataaagacta
     2341 tgagttattg aatcctataa taaaaaatat atttacaaaa tattactcaa aagattttga
     2401 agattatcga gacatagaag ttaaaccaga ccctaaaaag gtagggagaa aaattcgttc
     2461 tattagaaaa aaattaggac ttactatgca ggaatttggg tacgaggttt ctaattctcc
     2521 tagaagcact gtgtcaacat gggaacatgg tggtaactta ccgaacaaag ccaaactaaa
     2581 aaaaattgca gacattgcga attgtagtgt agaagatttg ctttttgatg aaggctttat
     2641 ttctgaaaaa tcccaagtta aattgataaa tgaactcaaa gaagaaaatt caaagctaaa
     2701 agaaaaaata aaatactatg aatgtttatt tgatggtata gagagtctgc tgaactcacg
     2761 aaaaaattcc tagttaatta aactagagta aaattatttg taggtgttaa atatgttagt
     2821 tggctatgca cgagtcagtt cagatgatca aaatttggaa agacagcttg aagaatttag
     2881 aaaaattggt gtcgaaaaag tatttgctga gaaaaaatct ggacgtaaca cagtagaacg
     2941 gccagagttc aataaaatgt tgtcatttgt cagagaaggg gatacgcttg tttttgagtc
     3001 gcttgaacgc ttaggaagaa attctgatga aatactagaa acagtatctt ttatagataa
     3061 aaatggtatg ggcttaatgg ttttgaattt accaatttta gatacaaaat ttggtgatcc
     3121 aaacttagaa aaacttgtta gaagcttagt aattaacatt ttttcttgga cggctcaaaa
     3181 tgagagggag gaaattaaga gaaaacaaaa acaaggaata gcaattgcga agaagaaagg
     3241 agtctataaa ggaaaaccct acgaatattc ttctactgca aagaatccac aaaagaggtt
     3301 tatctataat gaaatagtaa gaatgcttgg agaaggtgtt ccgattaagc gaattgcaga
     3361 aaaaacagga acaaatagaa atttagtcta tagaataaag aaaagaataa gtgaatctga
     3421 ttgattttaa gttctttgag aaatcaatgt tacgagagaa ggattctaag cctgtttcaa
     3481 acttttaagg tgtacaatta tacaaagaag cttctaaaca aaagaattaa ttttgtggca
     3541 gtcaagtaac gacagaaata gaaaagaaag aggctatgcg agagtgaatc aacaagttaa
     3601 ttgggttaat gattttgaaa aagaatttcg actgaaattt tttggaaatc ctacagcaga
     3661 aagtacagaa gaaaaaaatt atgactggtc agaattttag gttgcatatt cgattcaata
     3721 agtgttgaag ataatagttc tcttacgcca cagtatacaa cgttagaata tgacgaaaac
     3781 agattcaata catttccttg caataccatt caagaatcaa ttgataagca tgagtgataa
     3841 ttgattatct acaggaaggt gttttttatg aaactagaga tcaaagaagt tgtctgcgat
     3901 tggggaattt atgtagacgg agaaacatat ccatttatga tttttaatag taaagcaaat
     3961 gcacaagaga taatgcgtat catggagttg gataataagc acgaaagatt tgattaagta
     4021 aaaaaaatgg agaatgaatg tgaagcagtg gaataccaaa aaacatgcgc caataataag
     4081 tatattttag gtgcaatggg attaggtaaa tcagcttcta ttaaacaggt ctacgaagaa
     4141 tcacaggaga attgcgtata tgaaaattcg aattaaagag tgagaatatg tgggagctaa
     4201 tttatttagt tttatactta ataggaaaat caactgaatt tgtatataac aataaggtaa
     4261 tatttatatt gttcttaata gtttgtatta tcgtatttga tgtctatgat ttactaattc
     4321 ataagaatga aaatagtaat attggtagaa
//
LOCUS       DAJSMK010000137         4310 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.146, whole genome shotgun sequence.
ACCESSION   DAJSMK010000137 DAJSMK010000000
VERSION     DAJSMK010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.146"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(65..1285)
                     /locus_tag="ON488_002529"
     CDS             complement(65..1285)
                     /locus_tag="ON488_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HCR3232662.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1916)
                     /locus_tag="ON488_002530"
     CDS             complement(1305..1916)
                     /locus_tag="ON488_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HCR3232663.1"
                     /translation="MKMKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELP
                     LFNKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVD
                     KPVMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLID
                     EEQVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="ON488_002531"
     CDS             complement(1959..2891)
                     /locus_tag="ON488_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HCR3232664.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
     gene            complement(3312..4172)
                     /locus_tag="ON488_002532"
     CDS             complement(3312..4172)
                     /locus_tag="ON488_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232665.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT         1230 a          866 c          707 g         1507 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt tttttatata ataaggtaat tttaatataa aattttatat tgtaaaaaaa
     3061 caaataaggg aaacaaacaa cacatttttg tgtgttgctt atttccctct aactatcgtt
     3121 ttctatttga tggttaacct acttaaaata aatactgcaa cgacaaacgg agatcaagca
     3181 tgctttgtaa cgtattttac gataattacg actttatttt attactctat cttgctgcca
     3241 tacccgtcta tccctaatca tctttggtga attttttcaa agttagcata acaaaaataa
     3301 gtattttttc cttagttaat caatagtatc atttttttca tatgatttaa ttcatcaatt
     3361 aattttttgt ttttattaat tttagcaaaa gctagtgcat cttgaatcaa ttcgagcact
     3421 tctgccttcg acttattttt agcctgtgcg ttcttcgcta attgggcagc agctcgtgct
     3481 aagtaataag tcaaatggtt atccgaacaa atatcgattg cgtaatttag tagtgcatca
     3541 cttgtttcca aatcaccgtc ttgcgcaaaa aaaacaccac aatgaaagac gatatttaac
     3601 acccgccaga tatcttctgt tgtacgaatc ggatacgtat aaattttttc aaacactcga
     3661 ttgaaataaa cttctgcttt ttccaactct ttttctctag catagaccat tccaatacct
     3721 gtatatgcca ataaacgaaa caacgtgttg gctgtttctg ccatcaacaa ctgatcaaaa
     3781 tggaacaaca catccgtaat tggtgcattc gtaaaaatca tttcaaatcc ttttagatag
     3841 tagtaacgtg caatcagctc agactcgtca attaccttgg gatcaatggc tgctaaaatc
     3901 tgtgtcaatt gttcatattc actcgtaatc agtgaaaact ctgctttttc tagctgttca
     3961 tcaagttgtg tattgatcac gttcatcgaa gaaaaaagtt caactaacgg aagattgatt
     4021 cgattacata atttgattaa aatttttaac gaagggactt gaccattgtt ctcaaattta
     4081 cttaatgttg cttgtgtaca aattccttca gacacttctt tttgagataa gttggcagcc
     4141 tttcttgccg taataaattt ttcaatgttc attattttct ctccaatcag acctcacacg
     4201 aaaatcattt ctgtctcgat tttagcatgt tttctttggg aatgctttag gttctgttgc
     4261 aaagttttaa ataaagaata aagtccctta cggtatctat gatttaagct
//
LOCUS       DAJSMK010000138         4305 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.147, whole genome shotgun sequence.
ACCESSION   DAJSMK010000138 DAJSMK010000000
VERSION     DAJSMK010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.147"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            148..1137
                     /locus_tag="ON488_002533"
     CDS             148..1137
                     /locus_tag="ON488_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HCR3232666.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="ON488_002534"
     CDS             1134..1553
                     /locus_tag="ON488_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232667.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1532..1870
                     /locus_tag="ON488_002535"
     CDS             1532..1870
                     /locus_tag="ON488_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232668.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
     gene            1874..2236
                     /locus_tag="ON488_002536"
     CDS             1874..2236
                     /locus_tag="ON488_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232669.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVGNELRADEKSAPSERNYPNESDGIFGGIPNRK
                     SQMSESGFASMFSDVNSR"
     gene            2458..3864
                     /locus_tag="ON488_002537"
     CDS             2458..3864
                     /locus_tag="ON488_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCR3232670.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDSQKINDWHKHIDFTKSDEN
                     IYLEQINIREKYEELFGEAVEKYNAKQKRADRKIEDYLAKVRKDKKMEPQREFIVQIG
                     TLDDFRTTRDDGSSTGISEQQAEQNRVIANKILVEYFKEFKERNPSLSVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALQQQGLRADKENGRVIWNNFRNQEVESIE
                     RLMADFGWERELVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYICRQREE
                     NEREKALVASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVAALEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSEDEIEW"
BASE COUNT         1500 a          603 c          994 g         1208 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gctatcgtcg atttctgacg atcagcaaca cgaaaaatca gtgggtaatg agttgcgagc
     2101 tgatgaaaaa tcagcaccaa gcgaacggaa ttaccctaac gaatctgacg gaatattcgg
     2161 agggataccg aatagaaaaa gtcagatgag tgagagtgga tttgcgtcaa tgtttagtga
     2221 cgtaaattca cgataagcga atattttgca tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacggcga aaaccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtttaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaataaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat tgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatg gaaccacagc gagaatttat cgtgcaaatt
     2761 ggtactcttg atgattttcg tactactcgt gatgatggtt cttctactgg catatcggaa
     2821 caacaagcag aacaaaatcg agtgattgcc aacaaaattt tagttgagta tttcaaagaa
     2881 tttaaagaac ggaatcctag tttatccgtc tacaatgctg ttattcataa tgacgaaata
     2941 agtccgcacc tgcacttgaa tattgttcct gttgctgaag ggtataaacg gggtgttcaa
     3001 aagcaaccaa gttttaacaa agccttgcaa cagcagggtt tacgagcaga taaagagaat
     3061 ggtcgagtga tttggaataa ttttaggaat caggaagttg agtcaattga acgtttgatg
     3121 gcagattttg gttgggagcg tgagttagtc ggtactaaca aaatcaaaga tattcatgaa
     3181 tacaaagaaa tcatgagcga aatttccgaa ttgcgtcaaa cggccgtaaa agagcgtgag
     3241 agcgtttctg atgagttgag gtatatttgt aggcaaagag aagaaaacga gcgagaaaag
     3301 gctctggtgg cttctgagag agcgaagatt gaagaagaga agaaaaatat gctgaatgta
     3361 aaaaaagaga tggcggtcat tttccaaaaa gatatggttc ctttagaaag tttcaagagg
     3421 cttcctgatg gttcgtatca tttatctggg aatgattttg ttgatttgta tcaacgagct
     3481 acgagagcaa caaatgccaa gagaaatgct gataacatga gtgagcaata tttacagatg
     3541 cttgagcaaa atacagaatt aaatgagtat gtagctgcat tggaagaaga gcgtcatttg
     3601 tctggtagaa aacaattagc agatttacaa gtggaaaata aaaagctgaa agaagaaaat
     3661 cgctctttac gccagcgttt agagcgatta aaaaacgcat ttcaaaaatc gatcactcgt
     3721 ttgtctatcc gttttgggct tgcagaaaag gatatggggc tttctgagga attagaagta
     3781 ttagagcagg agaaaacctt attttatcgt caaaacgtct cacagcataa attagagcgt
     3841 tctgaagatg agatcgagtg gtagttacga tgtgcagtca acggtaccgg aggcggtttg
     3901 tgccgaggat aaggagttga cggctaaacc actagcctat taagctgaca tttgctaaaa
     3961 aatggcaagt ccattttttg gccaacttag cgttagcgaa gtttgggggc gcccttttta
     4021 aagggtgcgg ttttatgttt gcatgactaa gaatgagtgg gaaaatttaa cagccctatc
     4081 taacaggcgg ttaaatgtac aaaatatgta caccccctta aaaatgcagt ggtcgattga
     4141 tcgaatttta tgtctttggg ttttggggtt ttaaaacgaa aaaaaggggg cgattttcgc
     4201 cctctttttt gatgtttttt cttatcttga tactataggc aactatttct gcgaagaaat
     4261 cggggctata gtatgggtct atcccttgtg gctctaagga agaac
//
LOCUS       DAJSMK010000139         4296 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.148, whole genome shotgun sequence.
ACCESSION   DAJSMK010000139 DAJSMK010000000
VERSION     DAJSMK010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4296
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.148"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..791
                     /locus_tag="ON488_002538"
     CDS             <1..791
                     /locus_tag="ON488_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR3232671.1"
                     /translation="CGYSKTEPRHSFGPAIREQYLIHIVLEGEGYYSINDQKYFLKKG
                     QGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYYLKEIGVGKNHLTFKVENLNSFK
                     GLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSASYLNEGIITKKMNPFVRQTIEII
                     RENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISIKEYISEIKISIANDLLSSTEYS
                     IQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRLGLGIINGE"
     gene            888..3137
                     /locus_tag="ON488_002539"
     CDS             888..3137
                     /locus_tag="ON488_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HCR3232672.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3140..>4296
                     /locus_tag="ON488_002540"
     CDS             3140..>4296
                     /locus_tag="ON488_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HCR3232673.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRV"
BASE COUNT         1501 a          610 c          791 g         1394 t
ORIGIN      
        1 tttgtgggta ttcaaaaaca gaacctagac atagttttgg accagctatt cgagaacaat
       61 acttaataca catagtgcta gaaggtgaag gctattattc aattaatgat caaaaatatt
      121 ttctgaagaa aggccaagga tttgttatcc caccaggagt atctactttt tatcaagcag
      181 atgaaaaaaa tccgtggtca tatgtatggt tgggtttaag tggcaatctt gtagaatact
      241 atctaaaaga aattggtgtt ggaaagaatc atcttacctt taaagtcgaa aatttaaatt
      301 catttaaagg attaattttt gaaactttat cgtatgatca ggacaatcta gtcagtgaat
      361 tgtccagaca aaaacaagtt tataaatttt tagaactcct cttaaattca gctagttatc
      421 tgaacgaagg gataattact aaaaagatga atccttttgt tcgtcaaaca attgaaataa
      481 tacgtgagaa tgcgtatcaa aaattatctg ttaaagatat tgctgtcagt ctatcgatac
      541 acgaaaatta tttatcacga ttgtttaaga atgatatggg aatatcaata aaagagtata
      601 ttagtgaaat caaaatttct attgcaaacg atctgttatc atcaactgaa tattcaatcc
      661 agcaaatcag tgacaagata ggattctcaa cagtacaatc tttttctaaa gcctttaaga
      721 aagcaaatgg tgtttcaccg ggagtatatc gaaaacgtag attaggtcta ggaatcatta
      781 atggtgaata aactaaacat ttgattttga taaatattcg ttactttaaa cgcttactat
      841 ttatgtgagc gttttttata atgcaataaa gaaacggagg agagcttatg tataaggata
      901 atgaaatgaa tattatttat cgatcagaaa accaacaatt tcatttgttt aatcaggaga
      961 taagttacat ttttaagata tcggaagatg gtaaattatt gcatttatat tatggtgaga
     1021 acttaccaga taatgactat agtcatctaa ttgagatgca tcatcggcct atgacaacct
     1081 atagaaatga aaacgatttg ctatattcgt tagagcactt aaaacaagaa tttcctgaat
     1141 atggtacaac agattttaga catcctgcta tttcattact acagaaaaat ggctctcgct
     1201 tatcagattt tgtctatcaa gggtacgaag tggaagaagg aaaacctaaa ctagaaggtt
     1261 tacctgctac ctatgttgat aataatgatg aaagcaaaac attgaaagtt tatattttag
     1321 attcagttac aaatgttcaa gtagaattat tatatacaat ttatagagat tatcctgtta
     1381 ttactcgtag cgcgcgagtt atgaataaag gaaaagatat tcaaataatc gagaatatta
     1441 gcagtttatc attggattta cccgatgcaa attatgaatg gcaacaatta tctggtgctt
     1501 ggggtagaga aagaactatt aagtcgcgta ctttacaaca aggaattcaa tcaatcgaat
     1561 ctactcgagg tatttcaagc catcagcata acccatttgt tactttaaaa agaaaaaata
     1621 ctgatgaaaa tcaaggagaa gctattggtg cagcactagt ttactcagga aacttcttaa
     1681 ttcaagcaga agtagataca tgggatgtta ctagactaca agttggcatc aatccatttg
     1741 gatttaattg gaaactcaat ccaggagaaa tatttacagc accagaagcg attctggttt
     1801 attcaagtaa gggtttaaat gccatgagtc aaacttttca tcaactattt agaaaacgct
     1861 tagctcgtgg taagtggcga gaaaaagacc gtcctgtctt aattaataat tgggaagcaa
     1921 catattttga ttttgacgaa gaaaagttgg taaatattgc taaaaaagca tttgatgttg
     1981 gtattgaatt atttgtatta gatgatggct ggtttggaga aagagaaaac gattgtgcag
     2041 gattaggaga ttggcatgta aatcctaaaa gactacctag aggaatcggc agcctttcag
     2101 aaaaaattcg tagttttggt atgaaatttg gtttatggtt tgaacctgaa atggtgaata
     2161 aggatagtga gttatatcgc acacatccga attggattat ttctacacct aatcgaaaac
     2221 ctaatcatgg taggaaccaa tatgtattaa attttgggtt agatgaggtt gttgaaaata
     2281 ttttcgatca aatgtgtaaa atcattgatg aatcaaactt agattacatt aagtgggata
     2341 tgaatcgtcc attgactgat gtatttgaca gtcacttgtc agcagatcaa caaggagaag
     2401 tattccacag atatgtacta ggcgtatatc gcttatatga aaaacttata acaaaatatc
     2461 ctaacatact atttgagtct tgttcatcag gtggtgggcg ctttgatcct ggaatgcttc
     2521 actatgcacc tcaagcttgg gctagtgatg attcagatgc aattgaaagg ttaaaaattc
     2581 aatatggaac tagtatgctg tatcctcttt cgtctattgg tgctcatgta tcaattgttc
     2641 caaatcatca aacaaaccgt ataacaccta taaaaactag aggaaatgta gctttttttg
     2701 gtgcatttgg atatgagctt gacttaaatg aattaagtga aggcgatttg aggattgtaa
     2761 aagaacaaat tgccttttat aaaaaatata gaaccataat tcataatggt actttttata
     2821 gactattatc accattcgat gatgataatc aaaccgcgtg gatggttgtt agtcatgata
     2881 agaaaacggc tattgttgct cattataaaa cattaaatga ggtaaatgct ccttaccgcc
     2941 gactgaaatt aaaagggtta gataatgacg gactttataa tgtaggacaa aatagtttgc
     3001 gatctggaat ggaattgatg agagcaggac tagtctgttc agatgcatct agtggacaaa
     3061 taaatgatca gaatcgacgc ccagaaacat ttgattttga ttccaagatt tgggttataa
     3121 cacaggagga aaagtagaga tgaataacca aaaaagctta cttcaaaaag gagcaatctt
     3181 aagtatttca ctaatgttaa caagctctca agcaattaat ggtgttattc cacaaatgaa
     3241 acagtctttg gggatatcac aaagtcaaag tgaactttta ggaactgcac caagtataac
     3301 tgttattttg tttatcttat tatctagtta ctttgccaaa agaataggaa tgaaaaagac
     3361 aataatttta ggtttattat tagctggtat aggaggaatt attccagtat ttacagctac
     3421 cttccaaacc gttcttatta gtcgagtaat attaggtgcc ggtttaggag tatataattc
     3481 attggctgtg acatatatca gctctttata ctctggcaat actagagcaa cgctattagg
     3541 tattagaaat tcaatggaag ctttaggtca gacaatcctt atttttcttg ctggagtttt
     3601 agtgaacatt aattggacgg cttcgttttt agtctatgca attgcgtttc ctgtagctct
     3661 cttattcgcg ctaaaagttc ctgaaattag agatgaaaat agtgacatac ctgaaaatca
     3721 tgtaaaagaa aagatgaatc caatggtttt tgccctagtt ctatttgcaa tcttactcgt
     3781 aatgaatagt attgctattt ctgtacgatt tgcatcaatt gcaactgaaa ttaaaggggt
     3841 aaactttaat gctagtaact atttagctct aatgcctatc ttaggaatac tagcaggatt
     3901 tatgtttgga ccaataaata agtggatagg aaaaggaacc ctatacttgg gaattatatt
     3961 ctttataatt tcaaatttgt taattgctgt gtcaaacggt aatatgacgt tcctgctaac
     4021 gggtttattt ttatcaagta taacaggatc atggtgcttc ccatttatct ttagtaactt
     4081 agataaagtc actacaaaga atacaattaa ttttgctact tcattgattt ttattggctg
     4141 taatattggt aattttatag ctcctattgc tatgcaatta gcacaatttc taacaagaag
     4201 tacaaatttg actgctccat tttttgtatt cgcaggaata tttattgtga tcctatttgt
     4261 aacatttttt gcgacaaata aaaaaaatac tagagt
//
LOCUS       DAJSMK010000140         4217 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.149, whole genome shotgun sequence.
ACCESSION   DAJSMK010000140 DAJSMK010000000
VERSION     DAJSMK010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.149"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            75..503
                     /locus_tag="ON488_002541"
     CDS             75..503
                     /locus_tag="ON488_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCR3232674.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
     gene            490..732
                     /locus_tag="ON488_002542"
     CDS             490..732
                     /locus_tag="ON488_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232675.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(1032..1247)
                     /locus_tag="ON488_002543"
     CDS             complement(1032..1247)
                     /locus_tag="ON488_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232676.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            1354..1668
                     /locus_tag="ON488_002544"
     CDS             1354..1668
                     /locus_tag="ON488_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232677.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            1772..2950
                     /locus_tag="ON488_002545"
     CDS             1772..2950
                     /locus_tag="ON488_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3232678.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            3353..3646
                     /locus_tag="ON488_002546"
     CDS             3353..3646
                     /locus_tag="ON488_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HCR3232679.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
BASE COUNT         1446 a          627 c          820 g         1324 t
ORIGIN      
        1 tcctagattg tagtaataat ggaaagggat agaagtaaaa cgagttgaat gaattttttg
       61 agggggagaa tattatgggc gactcagagg aaacccacat tcaacatacg tttgacagtt
      121 tttgtaagaa agtagtctgc aatgaggcgt taaatattca aaagaagtac gctagatttc
      181 gccaacggca aatatcaatg gaaatattgg aacaaaaagg gttaggtaca gagttctatt
      241 atttggaacc aaatttgaat agtagtggta cttttattgt ccttggtatg aaaatcttta
      301 tttccaatga ggagttggca aatgcgattg cagcattacc tagtcaaaga caagaaatca
      361 tttttatgtc cttcttcatc ggtcttaatg atcgtgaaat tggcgatatt attgggaaaa
      421 gtctcggcag tgtttggtac caacgacaaa tggctttgga agagctagga aagtatttgg
      481 gtgtcaaata tgaagcaaaa taaacgatat ataccattca taccactaac gacaatcaaa
      541 gccgcagctt ctggtgattc aattgccatg tccatcgttc tgtcaaaata tcaaaattat
      601 atttcacggt tagccatgaa accagtttat gaagaagaaa aaggaatggt tatgtatgta
      661 gatgaatata tgcgtagaca actggaaaca aaattgattg agaagatact tgaatttgat
      721 acaactcgtt aaagtatttt ttccctttcc ttttcattct atggaagttt tttatcgggt
      781 caaaataaag gatttccata ggctgaaaat agcctagcgc tctttgacaa atgaatagca
      841 aatctatcag tacatgtaga ttttgattct ctagttacgc catgacaagg ttagctttta
      901 agcgacaaat tttaatatga gaatcgcgac tacgataatg atacttccgt aaccaaatcg
      961 gcccgccatt actgggggga ggtgagattc ctatgtgctt tggcaaaaca gctgatagat
     1021 cagaaaaact actatttcca tatttcgatt ttggttggca tatttttcat gccaaattct
     1081 gtgattttaa tagcatcggc aagatttaat ttttcttcag ctctctctcc acttttaagt
     1141 ttttttactg tactcaagtt gattcctgtt ccgaatgcta ttgcattagc cgtagatttt
     1201 tcaagaattt ctttaattat ttttatgtct gcaattcctt gtttcatatt aaaaattcct
     1261 cttttctagt ccgttttgat ggagtactgg agtgtttttt tacaatttta aggggtaccg
     1321 tggtggtcgt tttgattttg agagagaagg gtgatggagt tggaagttaa aacaaatgtt
     1381 aattctctgg aaatagagtt ctattcaatt ttacaaaaaa aactggaaga ttacacggaa
     1441 aaattgcttg cagtcagtca tttacctctg gtattaacaa atactgattt aaagcgacta
     1501 tttcagataa gtgatagtac actgaaccgt ttagtaaaac ttggtgagtt tcctccctgt
     1561 tggtacggga ttcgaggaca ctattttcgt gatgatgttt tagaatggat gagaaagagt
     1621 gattcgaatg actatcgaga aaaattgcga ctacttcgat ctttataagt tacattttct
     1681 ttctaagatg cggtacaatg atgacataga tagaaagatt tccaaagggt ttctgcttgt
     1741 tgggttcctt caaaatagga ggaatcaata aatggaaaaa acagatcgat tcaagaagca
     1801 aatcagttct actggtagga tcacatggta ctttcaagca tatcgaacaa caagacgtgg
     1861 ctttaattca aaacgtgagg cgcaactcgc ttatctggaa atggagaaac aacaaaggct
     1921 taagaaaaaa attgttgcaa gcaatgacaa gtttagtgtt gtaggtgagc aatggttcca
     1981 atattaccgt tcgttaaatg aacaaaagga aataacctat gataagcgag aggaacaatt
     2041 aaaaattatt gttcgatgga ttggtgataa aaagttgtct gatttgacac cagagtgcct
     2101 tcaagaattg ctttttacct taaaggaatg tggcgttaat ggaacaaatg ttggctatgc
     2161 caaaaatagt ttacaatcac ttattcaagt tctaaatatg atttttaaat attgtcaaag
     2221 aaagaatttg ataagtgaaa atccaatgaa gtctgtgaga atgccaaaat atcagttaac
     2281 ggtaactgat ttaaaagaag ccataaataa tattgaggac aagtttctta ctgtcgatga
     2341 attgagaact tttttgaatt atggcattgt tcatgaggaa ttaccgatgt ctgtactttt
     2401 ccatgttcta ttttacactg gctgccgagt cagcgaggcg cttgctctac agcctggaga
     2461 tatagatttc aaaagaaatg aaattctgtt ctataagcaa acggcagtta aaggtaagag
     2521 taaggatttt cgaattgaaa ctactaagac agttagttct gctagacgag ttctagtaac
     2581 tcctctagtt atggaaaagc tacaacagtt gattaaggct ttgggtgaga tgaggcaaca
     2641 ttacaggttt attatagaag aaacatattt gtttgtgtat cttgattcta gtaaacgtgg
     2701 tgttccttat cgtcgagagt atgtaaatga tcacgtcaaa cggtgcgtga atcgctcagg
     2761 aattaataag ccatttcata ctcatttagc tcgtcataca atggcaagct tagtagcgga
     2821 acactgtagc tgggaagtct tgaaagatcg cttaggccat actgaccaaa caacttcgaa
     2881 aatttatcgc cacttaacgt caaatgaaaa ggtaaaacct ctgattgctt ttagttcttt
     2941 agagagttaa aaaaacggtg aaagcactgg tattacagga ttcttgaaaa acgatttttt
     3001 aacaaattag tcaatatgta gtcagaggta ataaaaatcc ttttatatca atactttaac
     3061 gacttttcac aagtatcaaa gaaatccgtc gttaatcatt gttatcagac tgagaaagaa
     3121 cccttggtat tcaagggttc ttttttctta gcatgtaatt tgaacaccct gatccagttt
     3181 tttctttaat tattggtagg ggagaataat ggattagaat aaatctacct ataagtagta
     3241 gtaaaaaaaa gagcactatg ataatatctt tcttaagagt aaccgcttta ataaaaaatc
     3301 cagaatattc taacataaat ggagtattct tagaatcaaa aggagaaaga agatggttta
     3361 tacttatacg gagcaagaaa agatgaaagt tttagacaca ttcatgaatg atggaaaagt
     3421 aaaacaagta ccaagttcaa caaaaaagaa atacatccta ttgaaagaag tcttgaaacg
     3481 ctttgaccat ggagtgactt atacagaaac agaggttaat tcgatactgc tgaacgtatt
     3541 ttctagtggc gattatgtcg aacaaagacg ttatctaatc acatttggct ttttcaaaag
     3601 aagttcagac ggtcgggcat atcagatgat gggaattgaa aattagaagt tttaatttat
     3661 actcattgaa aaaagttcaa gtatgcgata ttggttctac accgcatact tgaacttttt
     3721 ttgtcatctg tatctataat acaaagccaa gaacgttatt caaaatatgg atagctatga
     3781 taaaagctaa tgagcgattc gcagttaaat aagcaatcgt cagtaaaatc gttccaggag
     3841 cgtacatgaa aaaatcaatt ggatgcgtta catgaataaa gataattctc ttttatttgt
     3901 acgaataaat accaaaacgt acctcctaaa attagatttt ggacagatgc cctttaaaaa
     3961 gataacaaga tttcgttctt gaaacaatat atatgctttt attccaatga ggttgtgaaa
     4021 acagtatttt gtcctgagcg ttagaaaatt gaaaatgggg aatagcaact cgtactttac
     4081 cattttttaa gtgaatacaa gatcagctag ttgaacaccg tttattcgtg atgagggaca
     4141 caacactgca gtcgacacat ttctctttta tgttcaaaga taacaaatat ttaaaacaaa
     4201 gaaaaatagt agataat
//
LOCUS       DAJSMK010000141         4003 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.150, whole genome shotgun sequence.
ACCESSION   DAJSMK010000141 DAJSMK010000000
VERSION     DAJSMK010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.150"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(243..392)
                     /locus_tag="ON488_002547"
     CDS             complement(243..392)
                     /locus_tag="ON488_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232680.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            854..1066
                     /locus_tag="ON488_002548"
     CDS             854..1066
                     /locus_tag="ON488_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232681.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            complement(1344..3143)
                     /locus_tag="ON488_002549"
     CDS             complement(1344..3143)
                     /locus_tag="ON488_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HCR3232682.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(3267..3863)
                     /locus_tag="ON488_002550"
     CDS             complement(3267..3863)
                     /locus_tag="ON488_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HCR3232683.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
BASE COUNT         1438 a          706 c          687 g         1172 t
ORIGIN      
        1 tatattaaat attatacaga taataacgga atattatcat cgaaacagct aacaaaattg
       61 tcataaaaaa cgagatggtt gatattagaa cttgtgtttt tgtttaggtc tagagataaa
      121 gagagacaat ttccaaatat atgtaatgaa tacaaaaaga cgtttgtcgc ggattaccgt
      181 tacaaacgtc ttttattgat tttccgagat ctcatcagtc gccatttgga atggttcact
      241 ccttatctag attcgtttaa tgctcggact gcttgttcga ttgtaatacc aaacgcaacg
      301 ttattttcgt tttgtgcatc aatcgccata aaacggttag aagttgtatc aaaagctacg
      361 cggtattgca tatttgtttt tgtaaacgtc ataaaattca tctcctttgt aatgtaattt
      421 agttcttgaa agtttccttt aaactttcga acttatacca agtttagcat cgtacgtttt
      481 ttgatgcaat taaaaagcat ttatcatttt ccttatttat tttttcttaa atggtttagc
      541 tattttcttt taatccgata agtagcccaa tcatcaaggt tacaaatact attgcttgaa
      601 tataaatcat atgctcacct ctttataaat aacttagcaa tataaagaaa aaaacgcacg
      661 aacaacatag gaatataaac aaacgttttt gtcacaacgt ctaagatcgt gttaaaaaat
      721 agttatctaa aaagcagaaa gatactcaaa ataaaaaata aaaaaatgga taaaaacgtt
      781 ttcaaataca aggtaatttg ttattataaa ataaagaaaa aacaaaataa aaataaagaa
      841 aagagggaat gaaatggtaa aagcagaagt aggaagatct tatatatgca aaccgatcgg
      901 agtatctcat gaactaatcg gctgtattga acgtacatat atcaacacgg ctgtcgtgta
      961 tgttgaaagt tatgaccaac gagactatca acttatcaat gaaagcaagt atcgcatgct
     1021 cgtaaaattc tgtgatatta gcgcacctgc tgaattggtt tcttaaacag tatttttgag
     1081 aattcgcaag aactccctta taatataaat aaagacagaa gggagcgaga agatatgcca
     1141 aaaagaaaaa gttcagggaa aatgggaatt attcttgcag tgatctctgc aattcctgct
     1201 attttagcta ttgttcgtgc gatgaaggaa tcaagagaaa gttaagcaca cattatgagc
     1261 gtcaaacaaa aaacgcatat acctgcggtg gcaggttatg cgttttttgt tgtataaaga
     1321 cttttttcat taacgatttt tgattagccg actcccaaaa caaaatttag cagtttatct
     1381 gaataagtga tttcttcatc tgtttgtttc acactttcat ttagtagtcc catctcatcg
     1441 gttatgatac catccacacc ataaaacatc atgcgactca tagcatctga atcgttgatt
     1501 gtccatacat atacttcttt tccgtcttgg tgggcagaat taatgaagtt acggttgatc
     1561 gtactatatt ccattgtcag aaaatcagca ggcgtcacag ggggcccaac aatattgaaa
     1621 ggtaagatgt agcccacata aaagtttggt tctgcttctt ttaaatctga aacggtttgg
     1681 tacgtcaaac tttgcaaaat atgatggttc tctaagataa ctttgcggta tttatggaca
     1741 aatcgttcga caaggtcatc cgaatctttt ttagaggtct tgatctcaat aagtaatttt
     1801 tggtttagct tatgtgcttt ttccaaataa gaatcaaaag aacaaacagg ggcttgcact
     1861 ccgttttcag taactgtaag atttgtcaat tctttcaatg taagatcctg tggtgttcca
     1921 tttacccctg ttaagtgacg aagatttgca tcatgcatca ctacgaaatg accatctttt
     1981 gtttcctgaa catccatctc tacataatca ggatgatagt ctctgcttgt tttttcaagt
     2041 gcttctaaag tattttgcgc cccattttgg gtactcacac ctctgtgaga gacagtcact
     2101 ggttttgtct gaacagctga agtcagataa tccatattgt aaagacagac gccaataccg
     2161 aaaaaaactg caaaaagagt caaaccagtg tttttcagcg cagagaaacg caagttgggg
     2221 gcttgtggga taaaccactt agggatctca ggcaagaagc cttcgtcatc catgaaatca
     2281 acaatgatat aaaaaatccc tacggtagac atcacgatat tgaataataa aatcccttgt
     2341 aaaagcgtca tagcaaacac agcgctgatc aatgcatagt ctgggaaaaa ttgttcaacc
     2401 atactttgtg ccaaaataac aacgatatat cctaaagaag aaaggagtaa aatcgtaccg
     2461 ccaatcacaa taaattggcc cgtgatggcc aaaagacgcg atttggtcaa tgaccagctt
     2521 tcccgaatgg ctgctcgaaa aggacgatct cgtagaatca tttccggtaa agcaaaaatc
     2581 agtcgaatcc caatatagcc aaggaaaata taaacgagta aaaaggaact gacgatgatc
     2641 caacgattag caaaaataaa atccataatg aaagcgggga tttttatttt tgacagtaga
     2701 tcagaattaa aacttaatcc gctgatcggt agaatcaata aaaaataagc aaggaaaaac
     2761 aaaaaagtaa tgggtctcac tttcttcagc tgaagtatcg tcaagtgtaa gagttgcttc
     2821 aaagagattg gttctttctt tttaataaaa aaaacactca tcaaaagaaa agtaaattcg
     2881 aaataaacta acagtaaaat cgtcatcaaa actacgatta acgagagtag aaccccagga
     2941 tgttgagaaa aaattgaagg aatattgtca taagacaaat agtcaattgc ccctcggtgt
     3001 aaaataaaac gggtcgtact gctcaataag ggtaaacaaa taaataaaat aaagccatgc
     3061 atcagcaaga catcacggaa ataagcttgt gttcctttta aaaagtccca agcattacct
     3121 aagctacgtt tcaaataatt catcctatca cctgctcttc acattgtagc gcaaatctaa
     3181 tgaaaaagga aagggtgcag tgtgttttgc agaccctttc ccagatttaa cattgtcaat
     3241 caatgactaa ttttacaaaa taaatattat ccaagaagac cacttagata ttgacctcca
     3301 taaatcaagg ccatactata taagaaaatc gacagtggtt tagcaatcaa aatgattagt
     3361 gtatatcgtt tcactgacat gtttgtcaat ccagccatca aacataacgc atcgtcagga
     3421 gcaactggaa gaaaaatagc tagagcaaac agcttctcaa aacggttttg attatccagc
     3481 cagccaatat atttgttata tgtcttatcg ctaatcatgg aaagtatgaa tggctttcca
     3541 taacgacgcc ctagcagaaa aatgataatc gaaccaatgc agattccaat atagttatag
     3601 ataaatccag cataagggcc aaatatcagg acaccagctg cagtactgat ccctccagga
     3661 atgattggaa taactacttg caggatttgg atgaagacaa aaataatcgg tcctaaaatg
     3721 atggaatcac ctactaatcc tcttaacgca ttcaaatctt tgaaaacacc taaattaata
     3781 aaataaatcg tcagcgcgat tgataggcct aatccgataa tggatatgaa atttatcagt
     3841 tttcgagagg cagcaatatt cattattcat caactcctta gaggttcttt gttaactata
     3901 ctttactaga aaagcaacta actgcgccat tttttgatat gacagaaaac aaacaatttt
     3961 gtaagttcat cataagtata aaagattgat ctcaaaaaaa cat
//
LOCUS       DAJSMK010000142         3931 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.151, whole genome shotgun sequence.
ACCESSION   DAJSMK010000142 DAJSMK010000000
VERSION     DAJSMK010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.151"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(579..1136)
                     /locus_tag="ON488_002551"
     CDS             complement(579..1136)
                     /locus_tag="ON488_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232684.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(1315..1926)
                     /locus_tag="ON488_002552"
     CDS             complement(1315..1926)
                     /locus_tag="ON488_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232685.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(2039..2296)
                     /locus_tag="ON488_002553"
     CDS             complement(2039..2296)
                     /locus_tag="ON488_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232686.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2893..3171)
                     /locus_tag="ON488_002554"
     CDS             complement(2893..3171)
                     /locus_tag="ON488_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232687.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(3205..3456)
                     /locus_tag="ON488_002555"
     CDS             complement(3205..3456)
                     /locus_tag="ON488_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232688.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1195 a          803 c          521 g         1412 t
ORIGIN      
        1 gcctccttat tccgaataaa tggtgtccaa aagcttgcat ctgccagatt atctcatttc
       61 ttatgacaag ctaagcaaat tatctccacc aaataattta ttcatatttt tgacttgcgc
      121 atactaacta attcttaaat tttcatacaa aatttctcaa tttcccttaa cgagtaatat
      181 ttatgtacgg tgattctcac tagtatccca atcacttttt aagttatccc gatttcaatt
      241 ctacttcaaa aatagttgct tttatgtatg ctgttagttg attagatggt catttgttga
      301 gctaggtcgt ttattttaaa caagttgttt ctttagctta tacctatctc gtctaccaaa
      361 cgcaagatgg caaacacaaa tgcatacgca tctgtatttg ccactttgat tcgtataaag
      421 ctaacaacta ttaactcctc tcagctaata gttgctctct tttttattca gattcatttt
      481 tgctgatcac agcctagtat ttcaatggtt ttgaacacta aaccaaattg ttccattaca
      541 acattcactg gctgatgaaa tggattagta gatttcgatt attcaaagcg attttctatt
      601 ggtggatcgt gttcccaact aataagacgg attccaaacc tatcgtacag atcttctaaa
      661 ccacttataa attttgcacc tatttcaggt gttttattgc gtggatattc tattgttacg
      721 ccattaaatg gataccaatt aggattaggc tctctttttt tctgtacatc tcccatagaa
      781 tagttagcac tttctgggac ataatatatt cttcgaccat cctctaattc atctaataag
      841 atatttcgtg atcgtctatc acttgctaaa tgtagacgcc acgtgcgata ccatgccatg
      901 ctacctgcat ctgcagaaaa tccatcaaat aatgcaacaa ttgtatcttc tatcacaatc
      961 ctttccccat ctacttcata ttctaatcta aaatcaaact cccctcgggt aatttctggt
     1021 cttggtggct taggacccaa tattattcta cttaaaaccg cattcgttcc cagatgaaac
     1081 acagctataa caacaataat gattaatatt ttgtttctat ttgataaatt tctcattatt
     1141 cgcacatcac ctctacattc tcacatatta gttcgtaata ctcctttaat atcaaaatat
     1201 ctactggtcg taataatatt cgctatgaat tcctactact cgtataagaa aggccaaatc
     1261 atcagctttt acttgctgat gatttggctt gtttctattt atcgtaattg ttttctaatc
     1321 accaaaattg ttaacaatcg gttcagatat ttcccagttg attaaggtaa ttccgtattg
     1381 tgtcaaaact tcttgcgctt ctccgaaatt aagtacagtt cttatgtatc cactttctcc
     1441 taatataaag tctacctctc ttttaaaacc ttcctcgaga tttctaaggg ctatatgtgg
     1501 ttttaatgac attgattgta cattttcccc catataatat tgcgcacttc ctcgactaaa
     1561 atagattcct agatcgtccc caaaaggtag atcttctcta ccactagcta atctacttct
     1621 ccatcttcgt tctcttttca tagaacctgc gctgaactca cacccgttaa actcagctat
     1681 gacagtatct tcaattatgt taatctgtcc atctagttcg tattcaatcc taaatggaaa
     1741 ttctccatag gtgatttccg gttcgggtat tttaggtgag attaatgcaa agaaaggaaa
     1801 tattaagctt ggcaacatca aaaaaactcc tcctatgatc acaattcccg atgtaatcca
     1861 aaatataatt tgtacaattc tcattgatcc attgtattcc attttattcc ccctattact
     1921 attcatatcc gcctatctat atcgatcttc caatgcagag ataattgctt ccataccttg
     1981 attttttact gagttaccta tgcgagatat cattctccac taaggtgcat catattgtct
     2041 atctaacatg attaattctc caataggtgt atactcctcc aaaaacaaca tttaatgcat
     2101 ctccctcgac aacataagct accatgtttg ctgtatatgt gtttgagtct aattcataag
     2161 cagataaatt tactgtcgct ggattaaata taatcgcatt cgtatttata gctactgaat
     2221 ttgctgcttc agcaccacct tttgaatgtc cgatcattgt gatttcaata gtaggattta
     2281 cgtggacagc cctcaccgtt taccctgacc attatagaaa tcgcttactt ttttgaacta
     2341 cgcaacaaag gatacaatgc tcctaacttc actgtctcca tttttgtcca ctaaggaata
     2401 taaaaaatag gcattaattc atttaattcg gtcacaacac gttacctttt aaatcattat
     2461 actgtatctc atacattatt atcaataaac tattataaaa atgcaaaaaa tgctttatca
     2521 atctattttg taattggtca taatatcatt gaaatcatac cctgtatcga tttttcctat
     2581 gaatctcgtc tatttgtgat tgacgaaaaa gaggcaagac agacactgga atggtaattt
     2641 tacccactat tttgctccaa ctatttgtaa tcgtacccac ttttgaaata ccgagatgat
     2701 cattttaatt gatatgctga ttcccaagca aaaccccaag aaattaaatg ctctatcgca
     2761 tctagcttct tgggttttgc ttatataaat tccaacattt aaatttttta tgctgttcgg
     2821 tctcagaaat gccgtttttg cttatatcac aatatcaaga tgtcaaatta ttcgtgttgc
     2881 cgatgacttt gattaatttt tttcaaattg tttattaaga ctaatgctgt ctttttgcag
     2941 ataccaatgt tcgaactttt taacattatc atatgatcct gcaagtttta acttcttacc
     3001 attagatgtt atcaaagtta taattaacct tgcctttttc ccattaggat cttttatttt
     3061 atgaattttc tgcaggtaat ctctcctaat ggcagctatt tttacctcat cagtgctgat
     3121 aaaccattga tcatccacat acatactgcc tgttatgttg tgtttttcca tttcttccga
     3181 gaacgaaaag tttaaggctc gttcttactt ccaaagttga atgagtccat ggattggact
     3241 tagtgtgaga attgagaaca acaataagaa tccatatcct cccgcaaaca tccctaaggc
     3301 tatactgtct ctccatccat aagtaggatt agaagagaaa agagtcaccg tttgtaataa
     3361 tatgaaaagg aataatccag cacaaacacc aaagataaca actccaaaca ttgaattttt
     3421 atacaatgac catttattta taggcttttc tttcatttta cttcccccta ctgttctgtt
     3481 cacacggaat gaattcaaag ttcataagcc ctcctctttg aacatatgaa tacgacttgc
     3541 taactatact ttaaaaaagc ttgttttaag cggttatagg cgagttgtaa tctctattca
     3601 tctcattagc aaataacttg ccgaaaagtc tactgaaatt aaagcagata gtggaagaat
     3661 tatttagcca ggatagacac tatttgtgaa acacatgtct ttacttttga aattctatga
     3721 tgaaaagcct tggaatacag tagctcttaa ttggtaatac tttttccatt ataaataacc
     3781 tcttttcatt ttatatttat cccctctaaa aataatatct aatctaatat tttaaactta
     3841 tatttccctc gctgtgctaa tagagcatta ctaaataaat agaaactaga aaaaagcatt
     3901 acgcctgcca gaataaacca attatttgta t
//
LOCUS       DAJSMK010000143         3662 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.152, whole genome shotgun sequence.
ACCESSION   DAJSMK010000143 DAJSMK010000000
VERSION     DAJSMK010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.152"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..275
                     /locus_tag="ON488_002556"
     CDS             <1..275
                     /locus_tag="ON488_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HCR3232689.1"
                     /translation="LIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERINE
                     LIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            418..639
                     /locus_tag="ON488_002557"
     CDS             418..639
                     /locus_tag="ON488_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232690.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            655..1497
                     /locus_tag="ON488_002558"
     CDS             655..1497
                     /locus_tag="ON488_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232691.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1560..3362
                     /locus_tag="ON488_002559"
     CDS             1560..3362
                     /locus_tag="ON488_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HCR3232692.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3421..>3662)
                     /locus_tag="ON488_002560"
     CDS             complement(3421..>3662)
                     /locus_tag="ON488_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCR3232693.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1306 a          519 c          745 g         1092 t
ORIGIN      
        1 aactcatcaa gctggctaat aagggtcaag attatgaaca tctagcagat gagattgatg
       61 agctgagaga caagcgacag ctccttttag tagaagatgc ctccctcagt ggcgagaacg
      121 agcgaatcaa tgagctgatt gaatttatcc gcaagaacaa attccgtacc ttagagtacg
      181 atgataagct tgtaaggaag ataatccaga gcgttacagt ctatgaagaa cacttcgtca
      241 tatccttcaa atctggcatc gaaatggaaa tatgaaaacc agaagtaaat agcccatgat
      301 tctacagtag agtcgtgggt tttcttttgc ttgctgatta taataatatt ttaataacta
      361 ttgttattat aaaccaaatg atttataata ttcttagcgt aaacttggag gtgctgtatg
      421 actacggcag aaatgattaa agaactgtgt gagcaaatga atataagtgt ttccgaactt
      481 gctagacgta ttggacagac tccacagaat ttcaataaga aattacaacg agaaacggta
      541 accttagatg agttgaaagc gattgctgat gtgctaggtg tcaagtttgt gcaggctttt
      601 atattgcctg atggcaatga aataaagata ggtaattagg aggtgtaatt tgtattgaaa
      661 atcataacaa taaatgatgt tgagtatgct gtatttgctg ctaatgaagg tacttccaaa
      721 ccacaacctc atatcataga aacgaaatct ggtactattc cagaaggaaa acaactgagt
      781 ttattaaaag aatatcttaa gcagaatgat atttccccaa taaaaggagc aacaacatat
      841 tggtgcattg acaaggttct taagcttgat tcaagtaaag aaaaaactat aagtgaaaca
      901 atccataaac aaaaatactt atctttaact gaagaaaata ttgagaaaca gcataagttt
      961 gtaggtgcaa gctctaatta tgggaaagaa ggtctaataa tacatgatgt tttgaatgca
     1021 tttcctcttc ataatgattt aaatactatt gcgatgaaga ttgcggtaat tgatgtaaca
     1081 aattcaacac atctttctca atataagagc aggttgtctc tatatgattt ggctaaagta
     1141 attctggaga ttccaaattt tgatgatcgg ttggcaaaag gagatcctca gttgataaat
     1201 attatcgcaa ggaacattgg tgcagttaat atgttctcat ttgcatccaa gtactgtaca
     1261 tatcataatg tggaagtgtg tgggagagat gattactcca tctttgatgg tatcgttaaa
     1321 aatactcttc cacactatat ccaaggacta actacgaata agattgatac gtggcgaaga
     1381 agttttgatt acgaggcatt taacgaatgt gttggaaaac tacttgatga aaataatata
     1441 catattcctt ttagaagaag aaagttagat cacttcttgt ggtatgcgaa taggtagaat
     1501 ataagaaaaa ggcatcgtaa aagtgattct ggataaaatt aatgggggag gaaataatag
     1561 tgggattatt tgattttcta aagaaaaaac aaggaaaggt tagtaaacac gttgattatc
     1621 aactggcttc tagtctattt cgtactggta aagtttttgc tgaaaaattg gaagtggaca
     1681 tatcaaatgt agatgagttt cgtaaaactt ttatcgcttt tgatgtggaa acaactggcc
     1741 taaattcttc ttcagataga attgtagaga ttggtgcggt gctatttaaa gaaggagttc
     1801 caattcaatc attcggaact cttgtcaatc caaaagttag aattgcagcc tcagcttcgg
     1861 caataaataa tataactaat gaaatgctaa actctgctcc aaatgagcag gaagtttacc
     1921 cccagttggt agaattttta ggagatgcac tagatggaaa aatcactatg tgtgcacaca
     1981 atgcaagttt cgattttgga tttttaagta acacattttc tagacttggg tatgatgcta
     2041 aaattaagta tgttgatact ctgagtctct ctagaaaaca tataaaaggc attgtaaatc
     2101 ataagcaaga gactgtagcg gaatatttcg gattaataaa tgacactgcc catagagcgg
     2161 aatcagatgc agatatatgc ggaaagattt tttggggtgt tttagatatt attgaggagt
     2221 cgttggaaga acaaaaaaag caaatagaaa agatgactcc agacataaaa gaacttgaag
     2281 cttgtgcttt tattcaagat attattgaga aaaaaggatg cgacaccagt tggatcaggt
     2341 atcgaaaaaa cagtaataat tatgtcgatg taacttgtct atatacattc ttaaagttta
     2401 agtttgctaa gaagggaaat tacatcatta ttagaaaaga tgctacaaat ggaattgatt
     2461 tacctataga accttgtact gtaagtgaag gcggtacaac aaatgtgcga gtctattttc
     2521 gtagcccctt tgacttaacg cctctttcaa attatatttt cagtgcttat agcgattgtt
     2581 ataattctat gaatgaatat atgagtgtta gtaattacac taaaaaagaa gcagagcaaa
     2641 gccttagtat gctgaaatct atttcaaaat cagcgatgaa agagttatta ttcgatgcaa
     2701 aaaatcgtgg atatgatgag actgaagtta acctaaatat tgaaaaagtg atatctagag
     2761 aagatgtaat tattaacggg ttgcataatc gagtttcatt aaacaagata cgaaatatag
     2821 ggaattggga gaaaggattt gatgcaggtt atccatattg ggaacgtgga gaaactgcta
     2881 ggaaaaatgg caaagtagat gaagctattg cactttttga taaagctcga tataacggct
     2941 atgatgctcc tgcgctatat gattcttatg ctaaagctta tcgaaaaatt aaggattacg
     3001 ataatgaaat tctcattctt gatgaaggaa ttatgcgtaa aacacggcac gatgttggta
     3061 ctttagaggc tcgtagggat aaggcaatta agctattatt tgctaaacaa gaggcagagc
     3121 ggatagctaa ggaaaaatct gattttctaa aagcgaacaa aaaagaggat gcgattagtg
     3181 agcctagcaa gaagcgtgga agacagatta ttcaaatgac tgatgatgga acaataataa
     3241 aagaattcga tactatagct tctgctgtaa aagaagttgg cgttaactca aaaagtatta
     3301 gggatgctgc aaatggagtt caaaaacatg ctggaggata ctactggaaa tacaaagatt
     3361 agcagataat ctaagataac ctaggatctt cttaatagat acccgtggtg ctagttaatt
     3421 ttaatatcct aaagaatatc tcaaagttcc ttcaaaacgt cgttgtgctc gacttaatag
     3481 aacactgtaa gccagtaata tgctttcaaa tctactctct agccctttaa cagaacgtga
     3541 gttgaaattt tgacaaccta atttttctaa ggaagaaaaa acagtcccaa ctgtttttct
     3601 ttgttttcca agtaagctgt ggtctagttt ttctgattta tccatgtttt tacgtggcgg
     3661 aa
//
LOCUS       DAJSMK010000144         3656 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.153, whole genome shotgun sequence.
ACCESSION   DAJSMK010000144 DAJSMK010000000
VERSION     DAJSMK010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.153"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            69..332
                     /locus_tag="ON488_002561"
     CDS             69..332
                     /locus_tag="ON488_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCR3232694.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            332..604
                     /locus_tag="ON488_002562"
     CDS             332..604
                     /locus_tag="ON488_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCR3232695.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            681..1010
                     /locus_tag="ON488_002563"
     CDS             681..1010
                     /locus_tag="ON488_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCR3232696.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1000..1286
                     /locus_tag="ON488_002564"
                     /pseudo
     CDS             1000..1286
                     /locus_tag="ON488_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            1570..2427
                     /locus_tag="ON488_002565"
     CDS             1570..2427
                     /locus_tag="ON488_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCR3232697.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            2428..2976
                     /locus_tag="ON488_002566"
     CDS             2428..2976
                     /locus_tag="ON488_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232698.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            3236..3531
                     /locus_tag="ON488_002567"
                     /pseudo
     CDS             3236..3531
                     /locus_tag="ON488_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1385 a          464 c          743 g         1064 t
ORIGIN      
        1 aaacaatcga atttacgtac ttaattaagt acgttagaat ggagatataa attagagggg
       61 gagtagatat ggcaaaaaca gtcttaaatc ctagctcagc acggaaaaat ttttataagt
      121 tgttgaaaga tgtaaatgag aatcatacgg aaattgaaat cattagtgag cgcagtgaaa
      181 ataatgcggt gcttattggt ttggatgatt ggaaagcaat caaagaaacg ctattacttg
      241 agcaaatagg cactttgggt gttgttcgta agcgagaaaa agatgatagt ggatttacta
      301 atgttgatga aattgattgg gataacttat aatgaataac tattctgtga tgattaaaaa
      361 ctcggctaaa gctgatttaa agaaaatcaa acagtctaat ttgaaacctc aatttgagaa
      421 ggttattcag actttaaagg aagatcccta tctccctacc caatcatttg agaagttaaa
      481 acctacacat gaaggtaggt attctagaag attgaataga caacaccggg ttgtttataa
      541 ggtagatgaa gatgaacacg tggttgaaat ttattcagca aggacgcatt acgagtcaca
      601 gtaattactt gtaaatacat tatctcgtgg tataatgtat ttactaagta attacatact
      661 gttagaaatg agggatttaa atgattacaa aaacaagaaa acaaggcaat tcaatcatgt
      721 tgacagtacc taaagatttt aatgttccta atggagtcga agttgaagca aagttggtag
      781 agaatggtat tctttatgaa tttgttgaac cacaaaaaga attttatgat tttagcgaag
      841 atattttgtc tgatataatt gcagaaggct acgataaaga tgagattctt gtagaattta
      901 agaatagaaa aaacaaaatg cattcttcct ttagagatat tgctgaagat acacttacta
      961 attctaaagt aatgactaaa gaggagttgg caacagaaat tggcttatga aatcgttcct
     1021 tcaaaacatg tcattaagta tttaaaaagc taaaagagaa gccattgaaa gaaaaatttt
     1081 tgaatttaat ttatgatgaa attgcgattg atccatataa gggtgaacaa aaaactgggg
     1141 atttatcagg tatttggtct agtgggttca aatatgcggg cacaacatat agagtagctt
     1201 acgagattat agaaaacaag gttattccag tattgttatg tggaacgcat gaaaactttt
     1261 atgaacagtt gaaaaaatta atctagtgat ttgttgtcgt tcttaagaag gacggcttct
     1321 ttttatcgaa aatctgattc gtctacatga ctaaagtcgc gagtattctc tgcttctcga
     1381 taaattaaat aacgtcatta ctttgaggaa agctataaat caatatattt cagcttttcc
     1441 ttatttatgt actacctttt acttattaat tataaggtag tacatatata tctttttttg
     1501 gtagtaacta aaaataaata tgttataata gtatcaaatg aatattgcta aaagaaaaga
     1561 ggtaggaacg tggtagcgaa gaaatatgta atcggtaatt ttaaaggtgg cgtaggtaaa
     1621 agtacgtgcg cgcaaatgtt agggtttgaa tcagcagtta atgaaggaaa aagaaccttg
     1681 ataattgact tggatatgca aggaaatact tctgatgtga tgaacttaac gcatatgaac
     1741 ttcactaacg aagaaggagg cggagaaggt gaaccgattg tttacgaaaa tactgtgact
     1801 gacgtgttga taaacaatct tccacctaaa gaggctgtct ataaagtaat caataacctc
     1861 tatatacttc cagcagacat gtcctttgaa atgtatgatg attggatcaa agaccaatat
     1921 aatgattcat tatcccaatt caaatatatg aaagaaaagc tagaaccatt atttgatgag
     1981 tttgacgtca tctatttaga tgtcccacct tctatttctg tatatagtaa atccgcgatg
     2041 tacattgcgg attgggcaat cgtcgtctta cagacccaag taaaatcgat gagaaatgcg
     2101 atgcaatatc ttgagtatat ggactttttt gtgaaagaat ttgatacaaa tttatatgtt
     2161 gctggtgtta ttcctttcat gttggaaagc ggtgacgcag tagatcagga aatgtataaa
     2221 caagcccaag agatttatgg ggaacatttg attaaaaatg ttgtactcaa aaatgcgcgc
     2281 ttaaaacgat acgacggatc aggtattacg atggagaaga caaagaaagg tctcttaaaa
     2341 caatgggatc gcaaaagcca cgaattattt atcagtattt tgaaagaatt ggaagaacac
     2401 gagaattggt atgcggaggt ggagtaattg gctgacatca aaggacttga tatttttggg
     2461 aacaacaaag gactcgccaa aataaaaaaa gaagcagaag caaagaaaaa gcagcaagca
     2521 attacaccat ctgaaaataa gcaattagaa gtgcaccaag ttcaagaaat aaaaacttcc
     2581 tccaatgttg aaagacagag tagaggaaga acaaaaaaag ttggcgcacc aatcagaaag
     2641 tttgataagg tttattccac caagcatcct ttaaaactgt cgactttgtt aaatgcgact
     2701 tccagagttt tagtagaaaa gtatgagact aatatgacaa gagatgaatt gcttagaaaa
     2761 gctttagatg agtatattaa acagaatctt acgcaagaag ataagcaaga tttgtttaat
     2821 gacgtggtga aagaactaga cttgttcaga gaaaaatatc caattgttcc agaattagat
     2881 gatcgtggag aaataataag aactaccagt cagataaaac aagataccga agactcactg
     2941 cgcaaagggt ggggaatgaa taataaagtt agataataat caaagaagaa ctaagtaact
     3001 acctttaaac ggtagttact tagttcttct ttgatttgca tgaaatagag gggatttatt
     3061 tttctggtta cgtgattaaa aaatccaaaa aatgagcata ggaacggtta tgattttagg
     3121 gtgtgtttta atgagatatt gtgatttcat taacaagtgt atgataatct gttgttgagt
     3181 tagtaaataa gtaatagagc taactctaaa ataaaactat taggaggaga tgtaggtgaa
     3241 aaagtttaaa aagaaaatat atttaggatt ggttgttggg gtgagtatgt ttgggttcat
     3301 ggctcatact aaacaagtaa ctgcagatac taaccaaaaa gaaaggatta tgagccaatt
     3361 agatgactct caaataagta tgtacccaat gagctaattg tcagtttaaa ggctacacaa
     3421 agaatttcaa cagagaaaaa taaaccgcaa aatttattgg gtgtaaaagt tatggtggaa
     3481 aaagatttga ctcttaggac aaatgaaagc gattgtaata agcgagatca agggttctgt
     3541 tgcaaagttt tccaaaaaat ctattttagt gtaaaattga gaaaaaagac agagaggaca
     3601 gagtaatgaa tcattttaaa ggcaaacaat tcaaaaaaga cgtcattatt gtcgct
//
LOCUS       DAJSMK010000145         3483 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.154, whole genome shotgun sequence.
ACCESSION   DAJSMK010000145 DAJSMK010000000
VERSION     DAJSMK010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.154"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            93..1052
                     /locus_tag="ON488_002568"
     CDS             93..1052
                     /locus_tag="ON488_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HCR3232699.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            1185..1391
                     /locus_tag="ON488_002569"
     CDS             1185..1391
                     /locus_tag="ON488_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HCR3232700.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
     gene            1402..2421
                     /locus_tag="ON488_002570"
     CDS             1402..2421
                     /locus_tag="ON488_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HCR3232701.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            2610..2683
                     /locus_tag="ON488_002571"
     tRNA            2610..2683
                     /locus_tag="ON488_002571"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2644..2646,aa:Ile,seq:cat)
     gene            complement(3196..>3483)
                     /locus_tag="ON488_002572"
     CDS             complement(3196..>3483)
                     /locus_tag="ON488_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232702.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT         1182 a          585 c          661 g         1055 t
ORIGIN      
        1 gccgattgta aaattaagct agacaactaa aaaagtcatt tgtgctacac tcaaaatagt
       61 tccgaccaaa gaattataag gagtgagtac aaatgaccta tacccatctt acaacggatg
      121 aacttgtaat aatagagtct tatttcaaaa tgaatcaatc tgttgctaaa actgcccatt
      181 gcttgaatcg ttcaagacaa acgatccata aagtatatct gttcttcaag caaggaaaat
      241 cagccttaga atattatcaa cagtataaga aaaacaaatc aaactgtggt agacgtccgc
      301 ttgttttacc cgaggaacaa tcagaatata ttcaaagaaa ggttgttcaa ggatggacac
      361 ccgatgtgat tgttggtcgt gcagcgtttc ctattagttg ttctgctcgt accatttatc
      421 gtatgttcaa aaaggggcta tttgattctt ctgacttacc gatgaaaggc aagcgtaaac
      481 cgaatggaca tcaagaaaga cgtggaaaac aaactttccg ccgctctatt catgaacgtg
      541 aaaaggatta tagccaattc tcaaatgagt ttggtcacct tgaaggtgac actatcgtag
      601 gtctgaaaca taaaagtgct gtaattacct tagttgaacg attatcaaaa gttatcatca
      661 cattgaaacc gtgtggtaga caagcgattg atattgaaaa aaaattaaat caatggtttg
      721 aatctgtacc gaaaaaccta ttcaaatcca tcacttttga ttgtggaaag gaattttcaa
      781 attggaaaca gatcagtaat gtcaatgata ttgccattta tttcgctgat ccaggaacgc
      841 cgtctcaaag aggcctaaac gagaattcta acggattgtt acgtagagat ggtttattga
      901 aatctatgga tttcaattca gtagatgaat tttttattca atctgtcgca tctaaacgaa
      961 ataatattcc tagaaaatca ctggattatc gaacaccttt ggaagtattt ttgagttacg
     1021 taagtattga tgatctgtct aacttaattt gacaattaag aaagataaaa ttgaacaact
     1081 ggacgggcaa attgatgcct tgctttcaga aagagaaata ttgatagaag aaaacaagcg
     1141 attgaaaaag aaagtagccc aaccaatgaa gggaggtgga tagtatgaac aatagaacct
     1201 ttgatatttt gaaatggatc gctatagtag ttatccccgc tttagcgact tttgtcggtc
     1261 ttgtcggaaa aggtgttaac tggcggtaca cagatataac ggtgatgatt attacaggtt
     1321 ttggagcatt tctagggagt attttaggtg tatcaaatcg aacgtataag aaaatttcat
     1381 cagataaata ggaggataga tatgaaaaag aaaattacta ttactgcgat gagcctgtta
     1441 acggctcttt ttttattgcc aattaacgga tttgcctata ctatcaacaa tgaatttaat
     1501 ttgggcgcaa atgaaggtag ctcacaagta gcaaataatc agtatatttt actgcatgaa
     1561 acggctaatg aaacagcaac aggacgcaat gaagcgcagt atatgcaacg ttcatggact
     1621 agcgcttata ctgcttatat tgtgggagac ggcggaattg tttatcaagt cggtcaacct
     1681 ggttatgtac agtacggtgc tggttcgtat gctaatgcca acagtcctgt gcagattgag
     1741 ttacaacaca cacatgataa agcaacgttt gagaaaaact acaaggcata cgttgaattg
     1801 gctagagatt cagcaatgaa atatggtatt ccattaacgt tggacactcc ttataaccaa
     1861 ccgggaatca aatcgcattt atgggtaaca caaaacatct ggggcgatca tacagatcct
     1921 tacggttatc tttctgaaat gggcgtaagt aaagaaaaat tagcatatga tttagctcat
     1981 ggatttaccg atgaaaatcc aacaacttct gaaaacaagc ctgtcattga tccaacacga
     2041 gctggtgcag ctaatcctac actgacagat ggaacgaatt acgcccacat tgatcagttt
     2101 ggagaaatcg aaaatgcaaa tttgcatgta gctggatggc acattgctaa ctataaatac
     2161 gagtatatct tcattatgga ttacaatact gggaaagaat tagctcgagt aagagctgat
     2221 ggaatttata gatcagatgt aaatcaagct tataatactt ctggaaatgt tggctatcat
     2281 gtatctttta acatgcgtaa cttccctaat aagaaagtct atgtcatgat gcgggcaacg
     2341 aatgatccag agggaaacac taaaggcggt gcgcaagatt tccatgacaa acgttggtat
     2401 ttaaatattc ctaaacgata aaaatagctc ctcgttgagg agcattacat aactatattg
     2461 acaactataa aaatcattcg ataaaatagt gatgttatcg catatcttca ctatcaccca
     2521 taatagtcac actccaagct atgcgataac aggtttgttg ccacacattc tactggttga
     2581 ttgtttatgg ctttatgtgg caacaaccag tacccttagc tcagttggtc agagcagacg
     2641 gctcataacc gtccggtcgt aggttcgagt cctacagggt acattaacgt agccatttga
     2701 atcgttctgt gttagaattt tttgaagagt attatacaag ctaaagcttt tcttcattgc
     2761 cactcaaatg agtggctttt ttatgtatcc ttttatggat taatgaaagg atgtttcaca
     2821 tagttatatt tctgtatatt tgaaaagttt tactttgatt tttaaataga aagacatttg
     2881 ggttaaattg tgagatgata ataaagaaga gtttaaagcg caccccaagc cacttcccca
     2941 taagtgtgtt acgctttaaa ctcttttata tttgaagcta ttaaaaggca taccatattt
     3001 ttgaaaaaaa gtgagaaaaa aggcttacaa ttggagtggt agttaattag tgacttattt
     3061 ttgattttat agcactgata ctataaaata tagatatcat catattacac aatcttaata
     3121 ctaacttaaa aaatatctcc tttcacaagt atggtgataa aattcgttcc gggctacctt
     3181 tttaggtagc ctactttaat ctttgtatct ttctggatca acgaaagtat actttatata
     3241 gtcataacgc cgatgatcgc tacgtgcgtc cggcacgtca gtcacgatat caaacaaaaa
     3301 gtatacatcc ttcttcattc tagttttcgc agcaggaatt ttgaaatagt tcttattaga
     3361 atagtagaga ttgattaata agctatcttc gattgctaaa aagaaaactt ctgaattcca
     3421 tactttataa aaatctttga taaatctatt cgaagggtca aatttaaacc ataattgtgt
     3481 ctc
//
LOCUS       DAJSMK010000146         3473 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.155, whole genome shotgun sequence.
ACCESSION   DAJSMK010000146 DAJSMK010000000
VERSION     DAJSMK010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3473
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.155"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..2232)
                     /locus_tag="ON488_002573"
     CDS             complement(<1..2232)
                     /locus_tag="ON488_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232703.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="ON488_002574"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="ON488_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          975 a          769 c          548 g         1181 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcaattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaaac attcgttaca tatttgtgaa tttttccaaa
     3421 aaataacatt tttataaaac gacgaaaaat aaatcactac cagtcaactt cta
//
LOCUS       DAJSMK010000147         3085 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.156, whole genome shotgun sequence.
ACCESSION   DAJSMK010000147 DAJSMK010000000
VERSION     DAJSMK010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3085
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.156"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            118..1740
                     /locus_tag="ON488_002575"
     CDS             118..1740
                     /locus_tag="ON488_002575"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HCR3232704.1"
                     /translation="MTEQIEKNSKSLYQALWNSADILRSKMDANEYKSYLLGLVFYKY
                     LSDNMLRYVSVLLEEETDDLNKAQDLYVEAFKDADIKDDLLYELKDEFSYTIAPALTF
                     TAQVAAIHDGSFQLEDLVQGFRDIEQSSENFENLFEDIDLYSKKLGSTPQKQNKTIAD
                     VMKELEGLNMAGHAGDVLGDAYEYLIGQFASESGKKAGEFYTPQPVAKLMTQIVLQGK
                     EDKKGFSVYDATMGSGSLLLNAKKYSHQPGTISYFGQELNTSTYNLARMNMILHGVPI
                     ANQHLHNADTLDQDWPTEEPTNFDGVLMNPPYSAKWSADKGFLDDPRFSAYGVLAPKS
                     KADFAFLLHGYYHLKDTGVMAIVLPHGVLFRGGAEGKIRKALLENGAIDTVIGLPANI
                     FFNTSIPTTVIILKKDRAKKDVLFIDASQDFEKIKTQNTLRDYHIDAILEAYKTRTIK
                     DKYAYVAEFDEIVENDYNLNIPRYVDTFEEEEVIPLDSVSKSIQETKAELAQAETELF
                     NMLKELNGTTEEAENELQAFISQLMTDGDNNE"
     gene            1721..2269
                     /locus_tag="ON488_002576"
     CDS             1721..2269
                     /locus_tag="ON488_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCR3232705.1"
                     /translation="MVIIMNKERAIPKVRFKSFSGDWKKLKLSSVTSRVRGNDGRMSL
                     PTLTISARNGWLDQRERFSGNIAGKEQKNYTLLRKGELSYNKGNSKLAKYGVVFMLDN
                     FEEALVPRVYHSFKTTNEASSKYIEYLFETKKPNKELRKLITSGARMDGLLNINYDDF
                     MGIKITIPKIKEQKKLDPYSNK"
     gene            2332..2985
                     /locus_tag="ON488_002577"
     CDS             2332..2985
                     /locus_tag="ON488_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HCR3232706.1"
                     /translation="MQQLFPQKGESVPKIRFTGFSDDWELKELKEFIGEDVSDGDWIQ
                     KEHIHESGEYRIVQTGNIGIGRYIDKPESAKYLNQESFDELKANEINPGDILISRLAD
                     PAGRALILPFTSSKMVTAVDVAIIRPNKNFISHFLVTRMNSSETLNDISKQVSGTSHK
                     RLSRKNLEKIELNVPNIEEQEKIGQLFKKLDEAIAGHEQKLATYQELKKALLQRMFV"
BASE COUNT         1129 a          527 c          603 g          826 t
ORIGIN      
        1 aaatgtagct tatccatttc attaaaatac atatggtgaa aaaacaagtt caaatagtaa
       61 ctaatttttt aaaaaactga tttataaaaa atacaacacg aatgaggaaa ataaccaatg
      121 acagaacaaa tcgaaaaaaa ttcaaaaagc ttatatcagg cactgtggaa ttccgcagat
      181 atcctgcgtt caaaaatgga cgctaatgaa tacaagagct atttactagg cttggtcttt
      241 tataaatact tatccgacaa catgctgcgg tatgtctccg ttctattgga ggaagaaacg
      301 gacgacctaa ataaagcaca agacctttac gttgaagcat ttaaagatgc agatataaag
      361 gatgatctct tgtatgaact aaaagatgag ttttcatata ccatcgcacc cgcattgacc
      421 tttaccgcgc aagtggcagc cattcatgat ggatcttttc aattagaaga cctggtacaa
      481 ggtttccgtg acattgaaca atccagcgaa aactttgaga acttatttga agacattgat
      541 ctgtattcta aaaaactggg gtcaacccca caaaaacaaa ataaaaccat cgcagatgtt
      601 atgaaagaat tagaagggtt aaacatggcg gggcatgctg gcgatgtctt aggcgatgcc
      661 tatgagtact taattggcca attcgcatct gaatccggta aaaaagccgg tgaattctat
      721 accccacaac cggtcgcaaa attgatgaca caaattgttt tacaaggaaa agaagataaa
      781 aaaggctttt ctgtttacga cgcgaccatg ggttcgggct cgttactttt gaacgctaaa
      841 aaatattccc atcaaccggg aaccatttct tatttcggac aagagttgaa tacgtctacc
      901 tataatttgg cgcgtatgaa catgattttg catggggttc ccattgccaa ccaacacttg
      961 cataatgcgg ataccttgga tcaagactgg ccaacagaag agccaacgaa cttcgatggg
     1021 gtgctcatga acccaccgta ttctgcaaaa tggtcggctg ataaaggctt cttagatgac
     1081 ccacgcttct ctgcctatgg cgtattagcc cctaaatcaa aagcggactt tgctttctta
     1141 ttacatggct actatcattt gaaagatacg ggcgtcatgg ccattgtttt gccacatggg
     1201 gtgctcttta gagggggcgc agaagggaag atacgcaaag ccttgttaga aaatggtgcc
     1261 attgacaccg tcattggctt acctgctaac atcttcttta atacgtccat tccaacgacc
     1321 gtaattatct tgaagaaaga ccgtgcgaaa aaagatgtgc tctttattga tgcgtcacaa
     1381 gattttgaaa aaataaaaac gcaaaatacg ctacgagatt accatattga cgctatttta
     1441 gaggcctata aaacccgtac aattaaagac aagtatgctt atgtcgcaga atttgatgaa
     1501 attgtggaga atgattacaa cttaaacatt ccccgttacg tggatacctt tgaagaagaa
     1561 gaagtgattc cccttgactc tgtttcgaag tctattcaag agactaaagc agagttagca
     1621 caagcagaaa ctgagttatt taatatgttg aaagaattaa acgggacaac tgaagaggca
     1681 gagaatgagt tacaagcgtt tatttcacaa ttgatgactg atggtgataa taatgaataa
     1741 agaaagggca atacctaaag ttcgttttaa aagctttagt ggagactgga aaaaattaaa
     1801 attaagttcg gttactagta gagtccgagg aaatgatgga agaatgagct taccaacatt
     1861 aacgatatct gctagaaatg gatggttaga tcaaagagaa cgtttttcag gtaatattgc
     1921 aggaaaggag caaaaaaatt atacgcttct acgtaaaggt gaactatctt ataataaagg
     1981 gaattcaaaa ctagctaaat atggagtcgt atttatgtta gataattttg aagaagcgct
     2041 tgttccaagg gtctatcata gttttaaaac tacaaatgaa gcatcatcaa aatatatcga
     2101 atatttattt gaaactaaaa agccaaataa ggaattaaga aaacttataa catctggagc
     2161 tagaatggat ggattattaa atataaatta tgatgacttt atggggatta aaataactat
     2221 tcctaaaatt aaagaacaaa aaaaattgga tccttattca aacaaataga tggcactatt
     2281 acccttcaac agcaactcct aaccgactac aagcaattta aaaaagcgtt gttgcaacag
     2341 ctattcccac aaaaaggaga atcagtaccg aaaattcgat ttactgggtt tagtgatgat
     2401 tgggaattga aagaattaaa agaattcatt ggtgaagatg tatctgatgg tgattggatt
     2461 caaaaggaac acatacatga atcaggagag tatagaatag ttcaaactgg aaatataggg
     2521 ataggaagat acatagataa gcctgagagt gcaaaatacc tcaaccaaga aagttttgat
     2581 gagttaaaag caaatgaaat aaaccctggt gatattttaa tatcccgatt agctgatcca
     2641 gcaggaagag cacttattct gccatttact tcttcaaaaa tggtgactgc agtggacgtt
     2701 gctattatta gaccaaataa aaatttcatt tctcattttc ttgtcactag aatgaattca
     2761 tcagaaacac taaatgatat ttcgaaacaa gtaagtggta cctcacataa aagattaagt
     2821 aggaaaaatt tagaaaaaat agaacttaat gtacctaata ttgaagaaca agaaaaaatc
     2881 ggtcaactct tcaaaaaact ggacgaagcc atcgcagggc atgaacagaa actcgccacc
     2941 tatcaagaac tcaagaaagc tctattacaa cggatgtttg tttaaagtaa agagaggagg
     3001 aacatcatgg cgattacctt tacatctgaa tcggaattag aacaaaccct catccatcag
     3061 ttgattgggg gggaatcaca atgga
//
LOCUS       DAJSMK010000148         3031 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.157, whole genome shotgun sequence.
ACCESSION   DAJSMK010000148 DAJSMK010000000
VERSION     DAJSMK010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3031
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.157"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            760..>3031
                     /gene="esp"
                     /locus_tag="ON488_002578"
     CDS             760..>3031
                     /gene="esp"
                     /locus_tag="ON488_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HCR3232707.1"
                     /translation="MISKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVKAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTDNWEIRLQLDERLAKYVENIQVDSKKVAGISYRRTF
                     VRINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKNLDEIFQEIGED
                     NLKSDRLMYRIYLVSHQDNDKIVPGIESTGYFITDQDNFYNKLDVSENNPDQFKHGSV
                     STKYEKPNVQTKDGSGSTGANGAIILDHKLTKEKNFSYSVSATGTPWYANYKIDERLV
                     PYVAGIQMHMVQADRVVYDVSFESGTKVADLAIERREGHENYGVGSITNNDLTKLIDF
                     SNASPRPVVIRYVLQLTEPLDEILAEMKTAAQVEGNEPFGEDFIFDSWLSDTNKKLIQ
                     NTYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAG
                     TGHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSNKLIAKDELKVQIVS
                     PGFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTS
                     NVADSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTIQSGKPTFD
                     KPDVPLANDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGETEPITGTIPIKIVYQ
                     DGSVGTTDLAVTVSKDI"
BASE COUNT         1097 a          439 c          596 g          899 t
ORIGIN      
        1 atgatgaatt tatggattat caaaaattgg atcagttaat tgaaagagaa agctgggaag
       61 attattacgt gggtctaact ttttcagaaa agttaaacaa ctacaagtta atagattata
      121 agtatttgag tgaaagcaat taattattca tgtagagtac tagacacttt aaatatggac
      181 aattcaatta taaagaaaaa gaatcaataa tttaatgagg ctgtgacaaa tgtcattttt
      241 tgtttcgcta aaaacgagtg aaaaaatgtt gataactcca atcattcgtt taagattcta
      301 ggaatcattc agaaatgctg tgaaaccgat actttataat tataaagaag gtgatttcaa
      361 attccgaaga aggaatttga agtcaccttt ttacttatgt cacagtctca ttcagtaatg
      421 cgggataagg ctccttattc cgctatttga atactctgaa gtttaatcta agaaagagta
      481 atattttgaa aacatgcttc atcgcataga aatgaactta atttcagaaa gaatacatac
      541 atatcttttt atatgttttc agctgctgaa tggttaaaaa gcacaaatat ccgaaaaaaa
      601 catgaagaaa tgtacttttt ttgttgtaat gtgcatgaaa ttctttaagt aaattagtta
      661 acataagttt aataagattc ctattctgtg aataatacgt atcagattta tcttttattc
      721 ttactaggaa aataactatt aagggagttg atttgaataa tgattagcaa gaataataag
      781 agagtatttc tagaaaaaac aaagaaacga gtattgaagt acagtatcaa aaaattaagt
      841 gttggggttg catctgtttt ggttggtgtt ggtcttgtct tgggaacaac tgaactagtt
      901 aaagcacaag atgaaatttc tccaagcacc ccacttgaaa cagcgataag ctccgtacaa
      961 gtaggtgaca aagtagcttc ggggaatact tttcaggaga atcctggtta tacgaaaaat
     1021 tataactttt cggatttaca atttagtcct caagaactaa ctggagacac actaaaaggc
     1081 aatacaattg gatttgaagt ttacggaaaa cataatattg ctgcttctac cgataattgg
     1141 gaaatccgcc tccaattgga tgagcgatta gccaagtacg ttgaaaacat tcaagtagat
     1201 tctaaaaagg ttgcggggat tagttacaga agaacttttg tccgaatcaa tgattcatta
     1261 ggtagaccca cgaacatttg gaaagttaat tatattcgtg caagcgatgg attatttgct
     1321 ggggcagaaa caactgatac acaaactgct cctaacgggg taattacatt tgaaaagaat
     1381 ctagatgaga tttttcaaga aattggtgaa gataacctta agagtgatcg tttgatgtat
     1441 cgaatctatc tggtaagtca tcaagacaat gataaaattg tacctggtat agaaagtact
     1501 ggttacttta taacagatca agataatttc tataataagt tagacgtatc tgaaaataat
     1561 cctgatcaat ttaaacacgg atcggtaagt accaaatacg agaaaccaaa tgttcaaacg
     1621 aaagatggat cggggtctac tggtgctaat ggcgctataa tcttggatca taagttaaca
     1681 aaagagaaaa atttctctta ctcggtttct gcaacgggaa cgccttggta tgctaactac
     1741 aaaattgatg aacgtttagt tccgtatgta gcgggtatac aaatgcatat ggttcaggct
     1801 gatcgagtag tatatgacgt ttcatttgaa tcaggaacaa aagtagctga tttagcaatc
     1861 gagcgacggg aaggtcatga aaattatggt gtaggttcaa taactaataa tgatttgact
     1921 aaacttatcg atttttctaa tgcaagtcca cgtccagttg ttattcgtta tgttcttcaa
     1981 ttgactgaac cattagatga aattttagca gaaatgaaaa cagctgcaca agttgaagga
     2041 aatgaaccgt ttggtgaaga cttcatcttt gattcttggt tgtcggatac gaataaaaaa
     2101 ttaatccaga acacttatgg aacaggttat tattatttac aagatattga tggtgatgga
     2161 aaccctgacg ataaagaaga gagtggagac acgaatccat atatcgggaa acctgaatta
     2221 gaagaagtat atgatgttga tacaacagtt aaggggaaag tattcatcca cgagttagcg
     2281 ggaacaggtc acaaagctca acttgttgat aaagaaggta ctgtattagc agaaaaaact
     2341 attgctccaa atgaaaaaga tggagctcca atttcggata ctgtagaatt tgaatttacg
     2401 ggtgtggatt caaataaatt aattgcgaaa gatgaattaa aagttcaaat cgtttctcca
     2461 ggttttgata aaccagaaga aggttcaacc gttatcaagg aatcaccaaa agcggttgat
     2521 aaacaaaccg tggtagttgg atttaaacca gatgctaaag aatcaattcg gaataataaa
     2581 aacttacctg aagatgcaga gtattcatgg aaaacagagc ctgatacttc taacgttgct
     2641 gatagtacga aaggtattgt aactgttaaa atcggaaatc gaacttttga cgtagatgta
     2701 gagtttgctg taaaagcttc tcaagctatg gaaaatgatg caacatacgt acctataaca
     2761 acaaccccag aaacgacaat tcaaagtggt aaacctacat ttgataaacc agatgttcct
     2821 ctagctaacg atgccttttc aattttagat gtttataata aggacttcgg caatgcaagt
     2881 gttgacgcaa atactggtat tgttacattc actccagcca aaggggtagg agaaacggaa
     2941 cctattactg gaacaattcc tatcaaaatt gtttaccaag atggttctgt aggtacgacc
     3001 gatttggcag taactgtaag taaagatatt t
//
LOCUS       DAJSMK010000149         3028 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.158, whole genome shotgun sequence.
ACCESSION   DAJSMK010000149 DAJSMK010000000
VERSION     DAJSMK010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3028
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.158"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..132)
                     /locus_tag="ON488_002579"
     CDS             complement(<1..132)
                     /locus_tag="ON488_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCR3232708.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
     gene            542..1687
                     /locus_tag="ON488_002580"
     CDS             542..1687
                     /locus_tag="ON488_002580"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HCR3232709.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1858..2316
                     /locus_tag="ON488_002581"
     CDS             1858..2316
                     /locus_tag="ON488_002581"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HCR3232710.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            2475..2945
                     /locus_tag="ON488_002582"
     CDS             2475..2945
                     /locus_tag="ON488_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HCR3232711.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT         1024 a          565 c          568 g          871 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaaatgata ttttacgagg aggaaagaaa
      541 catgcacatt caaacaaaat tgatccacgg aggcatcagt gaagatccca caacaggagc
      601 tgtcagtgta cctatttatc aaacatccac ttatcggcaa gatggcgtcg gccagcctaa
      661 acaatatgaa tattcaagat ctggtaatcc tactcgtttt gcattggaag aactgattgc
      721 tgatttggaa ggcggtgttc gaggattcgc tttttcttct ggtctttctg ggattcatgc
      781 cgttttttct ctttttcaag ctggcgatca tatcttatta ggagatgatg tctatggagg
      841 aacattccgt ctatttgaca aagttcttac taaaaatggt ctcgagtaca cgatcataga
      901 tacgagtaat cttgataaaa tagaacaatc catcaaaccc aatacaaaag cactttatct
      961 tgaaacacct agcaatccgc ttctaaagat tactgattta gaaaaaagtg ccactctggc
     1021 tcatcaacat ggattgatag ttattgctga caatacattt gctactcctt attttcaaag
     1081 acctttagat ctcggttctg atatcgttgt ccatagcggt accaaatatc taggcggaca
     1141 cagcgatgta gtagctggtt tagtgacttc taaccataaa gatctagccg atcagatcgg
     1201 attttaccaa aatgctatcg gagccgtact tggtccccaa gatagctggt tacttcagcg
     1261 cggaatcaag acactaagtg ttcgtatgga ggaacatcaa aaaaatgctt ttgtggtagc
     1321 tgattttcta ttttctcatc cagcagtaga aaaggtctac tatccaggat tacccgatca
     1381 tgaactccat ggagttgcta agcagcagat gagcggcttt agcggaatga tttcttttac
     1441 tttaaaaaat gaagaatctg ctattccatt tgttgaatca ctccaactat ttactttagc
     1501 agaaagttta ggtggcgtag aaagtttagt ggaaattcct tctgtcatga ctcatgcgtc
     1561 tattccaaaa gaaaaacgag aagaggctgg cataaaggac ggcttgatcc gtctttctgt
     1621 aggaattgag tatggtcagg atctcataaa cgatttagct caggcatttg acagaatcaa
     1681 gaactagaag tcccaataaa cgacttagca gaaaaatcta aaaaatattt cagattgcta
     1741 caccttggaa acgataagtg ttagaatcaa gtagaaagac gtttttgtaa atttcactaa
     1801 ataattcttt agtgaaaagc atcaaaacga atgaacaaac agataggagt cttacaaatg
     1861 agaatgaatg tcgaaagttt taatcttgac catacaaaag tcaaagcacc ttatgtacgt
     1921 gtagctgatc gaaaaacggg tgcgcatggc gatgtcatca ttaaatacga cgtccgcttt
     1981 aaacaaccaa ataaagaaca catggacatg ccaagtctac attcacttga gcacttgact
     2041 gccgaactaa tccgcaatca cgcagattac atcgtagact ggtctccaat gggatgccaa
     2101 acaggctttt acttgactgt attgaatcat gaaagctacg aagacatttt agatgttctt
     2161 gaagcaacaa tgaaagatgt tcttgaagct actgaagtac ctgcaagcaa tgaaacacaa
     2221 tgtggctggg ctgccagcca tacactagaa ggtgcacaag ctttggctcg tgaattttta
     2281 gcaaaacgcg atgaatggtc tgaagtagaa gcatagtttc taaaagaacg taaagatgag
     2341 aagcaatata gctatcttat cttcgtattt tattaaatat ttattgtctg aaaagagttc
     2401 taaacgggaa aacaaatagc tagttttcag tttagcgctc tttttattat ataaaataga
     2461 aaggagaaaa ctttatgtct atttataatt ttgaaactac tttagaagac ggcactgtct
     2521 attcattgaa aaaatatgca ggcaaaccga taatcattgt taacactgca acaaaatgcg
     2581 gtctagcacc tcaatttaaa caattagaag aactttacca agcttatcag acacaaggtc
     2641 tggttatctt aggctttcct tccaatcaat ttaaacaaga gctagattca gcgactgaag
     2701 cagcagaagc ttgtaaaacc acttatggcg ttaccttccc tatgcatcaa ttgattgacg
     2761 taaatggaga aaatacagat cctcttttta cttatcttaa aaatgaagct cctggtactg
     2821 tcactaaagc aataaaatgg aattttacta aatttttgat tgatagaaat ggcaaagtaa
     2881 tcgaacgatt tgcaccacaa acttctccat tgaaaatgac cgctgcaatt gaatccgttc
     2941 tttaacttaa taaaaataaa aaaagatgaa ctatttctag ttcatctttt tgcctttgcg
     3001 tggcgacgtc ctactctcac aaggggca
//
LOCUS       DAJSMK010000150         3008 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.159, whole genome shotgun sequence.
ACCESSION   DAJSMK010000150 DAJSMK010000000
VERSION     DAJSMK010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.159"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(276..692)
                     /locus_tag="ON488_002583"
     CDS             complement(276..692)
                     /locus_tag="ON488_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232712.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(695..979)
                     /locus_tag="ON488_002584"
     CDS             complement(695..979)
                     /locus_tag="ON488_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232713.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(1680..1775)
                     /locus_tag="ON488_002585"
     CDS             complement(1680..1775)
                     /locus_tag="ON488_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HCR3232714.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            2428..>3008
                     /locus_tag="ON488_002586"
     CDS             2428..>3008
                     /locus_tag="ON488_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HCR3232715.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALREL"
BASE COUNT          958 a          478 c          565 g         1007 t
ORIGIN      
        1 aaaaaaatac ttcaatgatc ttaaagtcac aaaaataaaa gcaaaaaagg gcaataaaat
       61 cgccaaatta gaatttactt tttcaagcct aacgtcagat ttgccaaaga tttctctgcg
      121 taactggtta gaagaataaa taaaaaagaa ctcgcccccc ttacattaag caagtagaca
      181 agtcccttac aaccgactaa gattgctagt acattctagc atattgtatg gggcttctaa
      241 ataaaaaaca gataggaata actcctatct gttttttatc gttttagaaa atttgttggg
      301 tcgaaatttc tagaagtgac tgtttgactg gtttcttttt gatgattctt tggtcgattt
      361 cgatttgatg gatttagttt agcttcgatt ttttctttca cttcttgata tactttagaa
      421 tttgtgccaa taagaacgcc tgtatctttt agatataaat cagcaaattc tgcgatgatt
      481 tcagtcatga tggaaatttc ttttcccata gcatttagtt ttgcctgatt gctggtagtg
      541 gtcgtgttgg tatcgggttc ataactcata cataaaaagc gaatggcttc cgagtagtta
      601 ttgatatctg gatttttttc gatgatggaa tctaaaacgt caacatgact agggtacaaa
      661 gtaacatgtt tttggacaga agtttttctc atggttatat cattcctccg ataagcattt
      721 caatgatttg attatttgtg tagacatact cgcttaatat ttgagtattt tctgtttgga
      781 tagcaataaa tttatcgagc aataaatcga attggtcttt tttgtaagtc gtaagttgac
      841 ggtcaaaatc actttcgatt aaaactttta gatatttatt tcgactccat ttttctcctg
      901 ttttattcgt gagttcttgg caacgtttgt ctattgttgc aacaaacttt ggatcaatat
      961 tccgaactaa aatgtccata aaaaatctcc ttttgcaatt atgtataatt tatgtatacc
     1021 atacaaatac tatatttgta tagctgtttt ttgccaaaat gctatacata agctacccac
     1081 gatggcgaaa aagtgatatc aaattttttt ctgagaaacg tgataggcac agcctatcta
     1141 cccacttttt ttagaaagtg ggtacacgtt tccttatgct ctttaaaatt cgggggggag
     1201 tgctgcacgt gtaatcgata accaaattta acagacgaaa aattgttgga atataaaaat
     1261 atgacacccg aaagaaaacg atcgttggaa aaattaatgc aactagtgaa cgaagacggc
     1321 ggaatttcag acgcagcttt tgacgcatgg agcgaatttc atggagaata taattaagtg
     1381 ggtttaaatg gctctaaaat cgcttctaag agttttttag cttggaccaa tgaaataaca
     1441 ccaaaaacta aataaaacgt cttaaatcga aaaatacgag ctctcagagc gactttattt
     1501 gtaaatgttg catataagaa ataattacgg attttagact tttgtaggat atttttgaaa
     1561 taaatattta tttctgttat aatttgattg caaataagtg aacacgaaac acacgaaatc
     1621 cccagagagg tcggattctc tggggctttt tttgtgggct gagtcgcctt aattaagttt
     1681 tacttcttgt ttcggttatt caaccagtaa ctgaacaaag cgcttaaaag cccaacaaga
     1741 agggagcaaa taaagttagt gaacacgaaa cacacctcct tccagtcgca agactgtcgg
     1801 ataggcgaca atcaattata caataaaaaa gcaaaaataa gcctaagttt tttattgcct
     1861 tggggttgtt agggcttgcc ctgaccgcct gtaaggcgct ttagaacgaa ggacatagtt
     1921 tttatcgaat cttgtcttag aacggcttag acgagctctc aggacgccac aaaggagtcc
     1981 ctaatgaatt atttttggcg aaggagccta aaggcgactg ctgcaagtaa aatgtgagag
     2041 cgtagcgatc actccttctt acagcgacca tagggagcta gattggcagt ttaatatcat
     2101 gcgcgaacct gtttatttta aaaagtgggt gattttttgg cgggaaattt tgctcgcgcg
     2161 cgcgcgttta ttttatttat tttttaaaga ttttttagaa ccctttttag ggggcagttg
     2221 agccttactc tcccaacgga tacagaaggg tactaacaac tttttatctg agtactaaca
     2281 actttttatc tgagtactaa caacttttta tctgagtact aacaactttt tatctgagta
     2341 ctaatatcct tttgtataat aacaaccaac ctatttacga gttggttgtt aaaggttatt
     2401 atttatttgt aaggggggaa gaaaggaatg gatgaaaaaa cggaattaac agtcaaatat
     2461 caaaatgaat tgaatttagt accgctgaaa aatttcaatg ctaagcagat ggatttattt
     2521 tttgcattat gcgctcgtat gaaagatcgt ggtttgaaaa aagttagatt ttctttcgag
     2581 gaattaaaag agttaagtga ttataagatg actgctacaa aagcctttgt cggtgattta
     2641 gaaaagctct ataaagatat gcttaatctt acttaccgta ctgaagatga ggattctatt
     2701 cgctactttg ttttgtttac tggttttgaa atcaataaaa caaaaaagtt tgttgaagtc
     2761 agtgttaatc cggacctaga atatattatt aatggtttaa cagctgaatt tagtagattt
     2821 gaattatctg ctttcacgtc gttgcgttct acgtatgcaa aaactctatt ccgactgctt
     2881 atgcagtacc gttctactgg ttattatgta gttcgtattg aagagtttag gagcttaatg
     2941 gatatcccag aatactatca aatgggtaac attgatcaaa aagtattaaa tcctgcatta
     3001 cgagaact
//
LOCUS       DAJSMK010000151         2969 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.160, whole genome shotgun sequence.
ACCESSION   DAJSMK010000151 DAJSMK010000000
VERSION     DAJSMK010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.160"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            1..441
                     /locus_tag="ON488_002587"
                     /pseudo
     CDS             1..441
                     /locus_tag="ON488_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
     gene            complement(518..1276)
                     /gene="istB"
                     /locus_tag="ON488_002588"
     CDS             complement(518..1276)
                     /gene="istB"
                     /locus_tag="ON488_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HCR3232716.1"
                     /translation="MTTNHQKVLTNLDELGLLKMKEYYPHYLDSVRNQTISLTDALYN
                     LTQKQLDYQKEMIDKRAIKLARFPTIKSLEEFDFEFQPSINKHDILQLKSFHFLESST
                     NICFLGNSGVGKTHLATAIGIEACIQGVKTRFILFNDLIEKLTRASQRGTLVRTLKIF
                     TNVPLLIIDEIGYTPISKTQADWFYQLMARRYERASTIITTNIPFSMWAKNFDNTTAS
                     AAILDRLIHHSKVFKITGNSYRLKNYHLDKETIG"
     gene            complement(1292..2518)
                     /gene="istA"
                     /locus_tag="ON488_002589"
     CDS             complement(1292..2518)
                     /gene="istA"
                     /locus_tag="ON488_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HCR3232717.1"
                     /translation="MRKDVYEGVRFFMINDIKPNFNELGRQYNCDPRTVKKYYLEGSE
                     NSVKKDKDKPKRPSKLDPFKEIIDQKLELNCSAMAIFKFLKKIGYQGGYTIVKDYCRN
                     KKHTEIKKATLRVETVPGTAAQVDWKEDMTLHDKFGKSYTFNLFLYVLHFSKLKFITL
                     TWDRKQDTLFSCLYEAFNHTGGVPKEIWFDNMKTVVDRARTQYRKVVFNTRFYEFSKD
                     AGFEAIACRSYRPQTKGSVESLAKLVERLKPYDYEFYDAVDLISLVNTLCYDLNYEEI
                     SQSTYQRPVDLWEREEKGKLHPVNEALLTPYFEDNIVRIVTNESMVNFRKSKYSVPTK
                     YIGCEVEIEIDPTEKFIEIFYQGEVVQSHELTGKRLNYKETDMFEILKSDVMKHKDDE
                     EIYEYIQRTLTQYDEL"
     gene            2626..2817
                     /locus_tag="ON488_002590"
                     /pseudo
     CDS             2626..2817
                     /locus_tag="ON488_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          943 a          481 c          504 g         1041 t
ORIGIN      
        1 ggagatattc gaaatttaga aaacatggtt tttaatctga gtaatggaat aattccaagt
       61 gttagtggag atacgattcg gtctgaaaaa aattattcta tcattgtttt tgaaaagtta
      121 gcacaaacgt ctataacatt aggaatggat ataatagaag cgtatcaaag tagagatgct
      181 ttgatacaag aaaacgaatt agctgtatcg ttacctgagg tcttaaaagt gagggattct
      241 gggattgttt attatactaa ggaaatcgga aaaactaaga tagagcatct ttctccctta
      301 atttcttctg tcgttcaatt catcggctta aatatctata aaagaattac tgtaaaggaa
      361 atagctaatt atttttctgt aagtgaaact aaattaagag aaagctttaa gaatgaaatg
      421 catattacga tttataatta ttgtcaatgg cggaataaaa atgctgtttt atggcggttt
      481 aaaaatgttg tttttcggcg gtaataaatg cctgttatta gccgatcgtt tctttatcta
      541 agtggtaatt tttcaatcga taagaattac cagtaatttt aaaaacttta gagtgatgga
      601 ttaatcgatc taaaattgct gctgaagctg tagtattatc aaaatttttc gcccacatag
      661 aaaatggaat gtttgttgta ataattgtag aagcgcgttc atatcgacgt gccatcagtt
      721 gataaaacca atcagcttgt gtcttactaa tcggcgtata accaatttca tctatgatca
      781 gtaaaggaac attggtaaat atttttagtg ttctaactaa tgttcccctc tgactcgcac
      841 gagtcaattt ttctataaga tcgttaaaaa gaataaacct tgttttgact ccttgaatgc
      901 atgcttcaat ccctatagct gtagccaagt gagtttttcc aaccccacta ttgccaagaa
      961 aacaaatatt cgtactactt tctaggaagt gaaaactttt gagttgcaga atgtcatgct
     1021 tattaatgct aggctgaaat tcaaaatcaa attcttccaa tgatttaata gttgggaagc
     1081 gcgcaagttt aattgcacgc ttatctatca tttctttttg ataatccagt tgcttttgcg
     1141 taagattata caatgcatct gtcaaagaaa ttgtctgatt cctcacggaa tcaaggtaat
     1201 gaggataata ctctttcatt tttaataagc ctagctcatc taaattggtt aacacttttt
     1261 ggtgatttgt tgtcattatt atttcagctc cttaaagttc atcatattga gtcaatgttc
     1321 gttgtatata ctcataaatt tcttcatcat ctttgtgttt catcacgtct gattttaata
     1381 tttcaaacat atcagtttct ttatagttca ggcgcttacc agttaattcg tgagattgta
     1441 caacctctcc ttggtagaat atttcgataa atttttcggt tggatcaatt tctatttcaa
     1501 cttcacaacc aatatatttt gtagggacag aatattttga ttttctaaaa ttgaccattg
     1561 attcgttggt gacaatacga acaatattgt cttcaaaata gggagttaac aacgcttcat
     1621 taactggatg tagttttcct ttttcttcac gttcccatag atcaacaggg cgctgataag
     1681 tggattgaga aatttcttca taattcaaat cgtaacagag cgtattcact aaactaatta
     1741 agtcaacggc atcatagaat tcataatcat aaggcttcag tctctcaact agcttagcta
     1801 aagattctac ggagccttta gtttgaggtc gataactccg gcacgcaata gcttcaaaac
     1861 cagcatcttt actgaactca tagaaacgag tgttaaaaac cactttacga tattgtgtac
     1921 gtgcccgatc aaccacagtt ttcatattgt cgaaccatat ttcttttggg acacctccgg
     1981 tgtgattaaa tgcttcatac aagcatgaaa ataaggtgtc ctgctttcga tcccaagtta
     2041 atgtaatgaa tttcaattta gaaaaatgta gaacgtacag aaagagattg aacgtgtaag
     2101 atttaccaaa tttatcgtgt aaggtcatat cttctttcca atcgacttga gcagctgttc
     2161 caggaactgt ttcaacacga agtgtcgcct ttttaatttc tgtgtgtttt ttattgcgac
     2221 aataatcctt aacaatagta tagccaccct gataaccaat ttttttcaaa aacttgaaaa
     2281 tagccatagc ggaacaattt aattctaatt tctgatcaat tatttccttg aaaggatcta
     2341 acttggaggg acgcttgggc ttatctttgt ctttctttac agagttttct gagccttcca
     2401 gataatactt tttgacagta cgtgggtcgc aattatactg gcgtcccaat tcattgaaat
     2461 taggtttaat atcgttaatc ataaaaaatc gaactccttc gtatacatct tttctcaatc
     2521 aattaacctc cattcagatt gagttaagaa aagtgtatag aaaaaaatgt aggaaaaacg
     2581 acatttttat tccgccgttt tcctacattt tatagccgcc atttacatta tatctctaag
     2641 cgaaaaattt ctacggctaa aataatgttg aaatcaaacc atactatcag tgaagtttct
     2701 ttaggtttag gattttcaga ttcttcacac ttttcgagag tattcaaaaa gtacgcaggt
     2761 gtatctccta agcaatatca attaggttta gtggacaatt tcaacaacat tagctgagag
     2821 gttttatttt attatgagac tatatcattt acgtagtttg gaggagttga ggaaattgga
     2881 ttttaacaaa aaattttttt gggaaatttc tgatttgagt tgtttcgtag aatctgagcg
     2941 tctaagtaat ggtaataata gtgtgttaa
//
LOCUS       DAJSMK010000152         2835 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.161, whole genome shotgun sequence.
ACCESSION   DAJSMK010000152 DAJSMK010000000
VERSION     DAJSMK010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2835
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.161"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            2..619
                     /locus_tag="ON488_002591"
     CDS             2..619
                     /locus_tag="ON488_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232718.1"
                     /translation="MLSVENFTLSINKKKIKQNWNFSISEKDFIIVTGKSGSGKTTLL
                     NNLSLIDKQYTGNLFYFEKKVSKHDIQRLRRNHISYLFQNYALLENQTVQYNFELAKK
                     FNSNISNDHIYNLLTDFSLPKDILKEKIFLLSGGEQQRIALIRNMLKPFDILFADEPT
                     GNLDKENSTFIMNFLKNLTEKEKKAVVLVTHDLNVLNYGTNIIEL"
     gene            733..870
                     /locus_tag="ON488_002592"
     CDS             733..870
                     /locus_tag="ON488_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232719.1"
                     /translation="MILLKKEYEKFYDRLIYSLQLPKKLNRQLQKTYETKSTEEWESY
                     C"
     gene            1312..1692
                     /locus_tag="ON488_002593"
     CDS             1312..1692
                     /locus_tag="ON488_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HCR3232720.1"
                     /translation="MSEQNQNLASNSSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVASG
                     DAQRLSENLKIMQKELQKIWQQLR"
     gene            1674..2588
                     /locus_tag="ON488_002594"
     CDS             1674..2588
                     /locus_tag="ON488_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HCR3232721.1"
                     /translation="MATIKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQTAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
BASE COUNT         1088 a          497 c          504 g          746 t
ORIGIN      
        1 gatattatca gttgagaatt tcaccctgtc aattaataaa aaaaagatca aacaaaattg
       61 gaacttttca atatcagaaa aagattttat tatagtaaca ggaaaaagtg gtagtggaaa
      121 aactactctg ttaaataatt taagcctaat agataaacaa tataccggta acttattcta
      181 ttttgaaaag aaagtttcta aacatgatat acaacgtcta cgaagaaatc atattagcta
      241 tttatttcaa aactatgctc ttcttgaaaa tcaaacagta caatacaatt tcgaattagc
      301 aaaaaagttt aacagtaata tttccaatga tcatatttat aatttattaa cagatttttc
      361 tttgccaaaa gatatcttaa aagaaaaaat ctttctctta agcggtggag aacaacaaag
      421 aatagcatta attagaaata tgttaaaacc atttgatata ttatttgcag atgaacctac
      481 aggaaattta gataaagaaa actcaacttt tataatgaac tttctgaaaa atttaacaga
      541 aaaagaaaaa aaagccgttg tactagtaac acatgactta aatgttctaa actatggaac
      601 taatattata gaattataat ttttacccgt gatgctagct gatttaaaac tagcaccacg
      661 ggtatttatt ttatattcca tctctcctat cccaaaattt aaataatcac ttaataaaaa
      721 ggaggcaccc tagtgatttt attgaaaaaa gagtatgaaa aattttatga tagacttatt
      781 tattctttgc aattgccaaa aaaattaaac cgtcaattac aaaagactta tgaaactaaa
      841 tcaactgaag aatgggagag ttattgctag atttttggta gaagtaacaa aaagtggaca
      901 tattatcata atgactcgcc gaaagtctga taaaaaattg gctaaaaata ttgctgaatg
      961 tttaataaaa ctatcagttt tagctaaata gttagtagtt tacacaaaaa agcatttatg
     1021 ttttttgttg caaagtaaca atttcatctt cggtgaaata agcgaaactt tacaaaaagt
     1081 ggctagcatt tgctagcttt ttttgtattg tggagcgtgg cttttgaggg ggattcaagg
     1141 gggagcttgc gcccctttga caagcggtta tttgcactaa atacgtaggt atttggctag
     1201 caaatataga gcttgccaaa cccttttagt gagctttact cattgtacct ttttaggtac
     1261 aatggtattg cgaacgatac gtccgtagga cgtactgaaa gggtgggact tatgagcgaa
     1321 caaaatcaaa atttggctag caattcttct aaaaaatata cctatcgatc cgagccaaaa
     1381 caaatcagtt ttcgagtgag cgaatccgaa tttgcaaagc tgaagcaatc ggctgaagct
     1441 ttgcaaatga gtgtgccggc tttcgtgaaa gccaaggcac aaaacgcgcg tctggtgaca
     1501 ccgaaagtgg cgccagacat tgcccaggca atcgcgcgcg atttagccaa agctggaggg
     1561 aatatcaatc aaattgctaa gtggtgcaat acacaccaac atgacgttgc ttctggtgac
     1621 gctcaacgtt tatccgaaaa cctaaaaatc atgcaaaagg agctacaaaa gatatggcaa
     1681 caattaaggt aagccgaacc acttcttgta gtcgtgcaat taattacgca gaaccacgag
     1741 caaccattaa aacaggaata aactgtgacg tcgattatgc caaaagtgaa atgaaacaaa
     1801 ttcgcatgct gtatggaaaa gacgaccgtg tacaggcaca cttattgatt caatcttttc
     1861 gaccaggaga aattaccgct gaaaaagcta atcaactagg ggcagagtat gcaaaaaaaa
     1921 tagcccccga tcaccaaaca gctatttaca cacatacaga caaagaccat attcataatc
     1981 acattgtcat taactccgtt aatctggaga ctggaaaaaa atttcaagct catggtcaag
     2041 catttctaaa caaatgttat gacctaaatg acgagatttg tcttgcacat aacttaccaa
     2101 tcactgagcg aggaaagaaa ccagaaaaac gaaccatgtc tgaaataaaa ttaaaagaaa
     2161 aaaatgaacc tgtttggaaa gacgaaattc ggattgcgat cgatcaaaca atgaaaaaca
     2221 aaaaaaccag aacctatgac caattttgta attccctcaa aacattgggg attcattgct
     2281 tcaatcgcgg gaaaaatttc acttacgaat tgatccacaa aaagaaaaaa gtacgatcca
     2341 acagactagg aaaggactac gaaaaggaga cgattttaca tgagctggac agacgagaac
     2401 gaacctataa ccaacagcga accaacgagc tacgaagagc tcgagctagc attcgcgaaa
     2461 ctgcagaaga agtacgaaga gaacaacgaa ctcttacgcc tgaacaaccg gaaattagac
     2521 cggctcgaag aaaccatgaa caacacgttg aaagaggaac agaccaccaa caagaattat
     2581 cgctctaaaa cgttaaaaga catagaaaac gaaataaaga aacaacgtgc ttttctcgtt
     2641 ccttatacgc aagaaaggat acaaactacg attgatttac aagttaaaaa actccatcaa
     2701 gagctattag accagcgaaa taaggaacag aaaaaggtgc ttattcaacg atcattggat
     2761 tttcttgccc ccttatgttg cttagtcctg acactgttcg cattttggtt agtatgggga
     2821 ggctaaaatg gcatt
//
LOCUS       DAJSMK010000153         2799 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.162, whole genome shotgun sequence.
ACCESSION   DAJSMK010000153 DAJSMK010000000
VERSION     DAJSMK010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2799
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.162"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            96..506
                     /gene="spx"
                     /locus_tag="ON488_002595"
     CDS             96..506
                     /gene="spx"
                     /locus_tag="ON488_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HCR3232722.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     TLAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLLKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            520..876
                     /locus_tag="ON488_002596"
     CDS             520..876
                     /locus_tag="ON488_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR3232723.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVEKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            1547..>2799
                     /locus_tag="ON488_002597"
     rRNA            1547..>2799
                     /locus_tag="ON488_002597"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          885 a          511 c          668 g          735 t
ORIGIN      
        1 ttattttgat ttttttttat attttattag ctaataattg gtattttaaa agaaattact
       61 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
      121 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
      181 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagacc ttggcagcga
      241 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
      301 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attgaaagaa tatccttcat
      361 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
      421 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
      481 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
      541 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
      601 tatcaatttg ttgacttaga agaacgcgat ctaagtacag aagaagcaga agaattatgc
      661 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
      721 attgcgattg acctttcctg tgtagaaaaa aaacaactga tttttttatg cacacaacat
      781 accaacctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
      841 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
      901 ctgagcattc catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
      961 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
     1021 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
     1081 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
     1141 ttgttgacat gttagaaatg acatgataag ataactgagt cgttaaaaaa ggaccgcttg
     1201 cgaagcttga ttctatcgaa aaaacttcaa aaaagttctt gacaaataac aaacgacaag
     1261 ttatgataaa tgagttgctg taagatttcg aaaaacgaaa tcaaaaaaac ttttaaaaaa
     1321 gagttgacaa ttacttgtct ctctgatacg atataaaagt tgctgcggca gccaaaaacg
     1381 aatcgggaaa cactcctgat gaagtagacc tttgaaaaat gaacaaagta agacaaacca
     1441 aatgtgtagg gcgtcttgat tcaattcaag acaacaaaca tttttaacaa gcaagcaata
     1501 tgctagcaaa caaattgagc ttaacaatcg caaggttgtt cgaacttttt atgagagttt
     1561 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtcg aacgcttctt
     1621 tttccaccgg agcttgctcc accggaaaaa gaagagtggc gaacgggtga gtaacacgtg
     1681 ggtaacctgc ccatcagaag gggataacac ttggaaacag gtgctaatac cgtataacaa
     1741 tcgaaaccgc atggttttga tttgaaaggc gctttcgggt gtcgctgatg gatggacccg
     1801 cggtgcatta gctagttggt gaggtaacgg ctcaccaagg ccacgatgca tagccgacct
     1861 gagagggtga tcggccacat tgggactgag acacggccca aactcctacg ggaggcagca
     1921 gtagggaatc ttcggcaatg gacgaaagtc tgaccgagca acgccgcgtg agtgaagaag
     1981 gttttcggat cgtaaaactc tgttgttaga gaagaacaag gatgagagta actgttcatc
     2041 ccttgacggt atctaaccag aaagccacgg ctaactacgt gccagcagcc gcggtaatac
     2101 gtaggtggca agcgttgtcc ggatttattg ggcgtaaagc gagcgcaggc ggtttcttaa
     2161 gtctgatgtg aaagcccccg gctcaaccgg ggagggtcat tggaaactgg gagacttgag
     2221 tgcagaagag gagagtggaa ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa
     2281 caccagtggc gaaggcggct ctctggtctg taactgacgc tgaggctcga aagcgtgggg
     2341 agcaaacagg attagatacc ctggtagtcc acgccgtaaa cgatgagtgc taagtgttgg
     2401 agggtttccg cccttcagtg ctgcagctaa cgcattaagc actccgcctg gggagtacga
     2461 ccgcaaggtt gaaactcaaa ggaattgacg ggggcccgca caagcggtgg agcatgtggt
     2521 ttaattcgaa gcaacgcgaa gaaccttacc aggtcttgac atcctttgac cactctagag
     2581 atagagcttc cccttcgggg gcaaagtgac aggtggtgca tggttgtcgt cagctcgtgt
     2641 cgtgagatgt tgggttaagt cccgcaacga gcgcaaccct tattgttagt tgccatcatt
     2701 cagttgggca ctctagcaag actgccggtg acaaaccgga ggaaggtggg gatgacgtca
     2761 aatcatcatg ccccttatga cctgggctac acacgtgct
//
LOCUS       DAJSMK010000154         2727 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.163, whole genome shotgun sequence.
ACCESSION   DAJSMK010000154 DAJSMK010000000
VERSION     DAJSMK010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2727
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.163"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..429)
                     /locus_tag="ON488_002598"
     CDS             complement(<1..429)
                     /locus_tag="ON488_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3232724.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQ"
     misc_feature    642..767
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            811..1335
                     /gene="infC"
                     /locus_tag="ON488_002599"
     CDS             811..1335
                     /gene="infC"
                     /locus_tag="ON488_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HCR3232725.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            1407..1607
                     /gene="rpmI"
                     /locus_tag="ON488_002600"
     CDS             1407..1607
                     /gene="rpmI"
                     /locus_tag="ON488_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HCR3232726.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1660..2019
                     /gene="rplT"
                     /locus_tag="ON488_002601"
     CDS             1660..2019
                     /gene="rplT"
                     /locus_tag="ON488_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HCR3232727.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            2371..>2727
                     /locus_tag="ON488_002602"
     CDS             2371..>2727
                     /locus_tag="ON488_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HCR3232728.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLG"
BASE COUNT          874 a          480 c          577 g          796 t
ORIGIN      
        1 ctgttctgtt aagctagaaa cgaaggactt agagacggat ttaccacaaa gttcttccac
       61 aatttttgat actttacgag ttgaaacgcc tgatacatac atttccaaca ttgaagccat
      121 gagggctttt tcgtttcgtt gataacgttc aaacactgtg ggtgaaaaat ggccatcacg
      181 tgttctgggt acttttaatt ctagcgtgcc tacacgtgtc gtaaagctgc gctcataata
      241 gccatttcgt tgactttgtc ggttttctgt tcgttcatat tcttttgctt gaatatattc
      301 tgttcgttga ttttccatta gttgattaaa taccgttgtt aaaatatttt tagaaacgtc
      361 atcctttaca gaatattcaa taatgctttg aatctcttcg cttttcagtg taaaatgtac
      421 ttgggtcatg taaaagtcct cctgggtatg tttttgtcgt taaaaacatt gtaccgtaaa
      481 aggactgtta tatggccttt ttacttttac acaattatac ggactttatc gggaatcact
      541 gctagaaagc ctgctaatct aatcattttc agaaaaggaa gacaaactgt atgaaaaaca
      601 ttgacaaaaa gattagtttt tgctatacta taatggttga gaaataaaag cagaagcacc
      661 cgcttctcgc cttagttgat aatgtcactg ggctagatag ttttcactgg ttctattagg
      721 tgaagtacgc gcgggttctg taagagaact cgttttttta ttgccgttta ttcggtaagc
      781 ttttctttct ctcataatat ttggaggtga atgaccatag caaaggatat gatggttaac
      841 gacggcattc gtgcacgaga gttacgattg atcggttcag atggtgagca attaggagtt
      901 aagacaaaag cagaagcatt gaatattgca gaacaagcaa acttggatct tgtgttagtt
      961 gcccctggtg cgaaaccacc agttgcgcga atcatggact acggtaaata ccgtttcgaa
     1021 caacaaaaga aagaccgcga agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt
     1081 cgcttaagtc ctacgatcga cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag
     1141 ttcttggaaa agggcgataa agtgaaagct tctatccgtt tcaaaggccg tgccattacc
     1201 cataaagaaa ttggtcaaaa agtcttgaat cgcttagctg aagaaactgc ggatattgca
     1261 acagtggaac aaaaagcgaa aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa
     1321 aacgacagta agtaatttga atgactaact ggctgttgga cagccgatag tcggataacg
     1381 aaagattttg aggaggaaat atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa
     1441 aacgtttcaa acgtactggt aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc
     1501 gtttccacgg caaaacaaaa aaacaacgcc gtcaattgcg taaagcaagc atggtttcta
     1561 gtggcgactt caaacgtatt cgccaacaac tagcaaaaat gaaataagaa gtacaaataa
     1621 cagaatctga agatttattt ttattaggag gaattataca tggcacgtgt taaaggtgga
     1681 acagtaactc gtaaacgtcg taaaagagtg ctaaaattag caaaaggtta ctacggttca
     1741 aaacacactt tatttaaaac agcaaaagaa caagtaatga attcatacaa ctacgcatat
     1801 cgcgatcgtc gtcaaaagaa acgcgacttc cgtaaattgt ggattgctcg tatcaacgca
     1861 gcagctcgta tgaatggctt gagctactca aaattaatgc acggtttgaa agttgctgaa
     1921 atcgacatca accgtaaaat gttagctgac ttggctgtta acgatgcagc agcatttact
     1981 gcattggctg accaagcaaa agaagctttg gctaaataag ctaaacaatt ataaagagga
     2041 aagaagataa cgaaaagtta tgttctttcc tcttttttta tttacaatcc tccatcaaat
     2101 gaaacaggac aataacgtat aagtctaaaa taacataatt aaggtttttt aattgaaaac
     2161 tgaacattta tggtcatcct ttaatgaaag cgctaactac ataagttaga atgagtttga
     2221 ctgatatatt agtttgctta tcagaaaaac aaaatggacg gaggaataac atgagtgata
     2281 ttattattgg tattttgtta gttatctcat tctttttcat ggtctggtac tgtgtaaaag
     2341 gctacaactt gatggtcggc ttttgtcatc atggctactg tatggatggg attagcgcta
     2401 gtcggaaaca cgttttcacc aaactcggcg atggaagggc aaggagtaat tgatgtgttg
     2461 acgcatatct atacgacggg gccagctgag tacgccaaat cgatcttggt aaatgtcttc
     2521 tttggtgcct ttttcgggcg tgttctagta gatagcggaa tcgcagctac cctgattcga
     2581 aaggtagttg aacttggagg ggacaagcca agaatcacga tgagcttact atgtattgta
     2641 accgctgtta tattcatgtc gatgacagga atcggaccag tgatttctat tgcagttatt
     2701 gtgttgccga tcttgatgtc attaggt
//
LOCUS       DAJSMK010000155         2640 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.164, whole genome shotgun sequence.
ACCESSION   DAJSMK010000155 DAJSMK010000000
VERSION     DAJSMK010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.164"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            724..2550
                     /gene="ltrA"
                     /locus_tag="ON488_002603"
     CDS             724..2550
                     /gene="ltrA"
                     /locus_tag="ON488_002603"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HCR3232729.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
BASE COUNT          948 a          461 c          584 g          647 t
ORIGIN      
        1 aaaagagtag gcacagcact tcattaaatc aatatttaat gtgtgttgga gaactaaaca
       61 cacgaatagt cgaatgacgg ggtaacgccc tgaaaggcta ctttaatact ctgactggca
      121 gaaacttgag taaacaaggc tctgtcagaa gctcggtgaa gtcggcagac agacaccgta
      181 acagataatg ctgacgaaag attcccagag gtgggcgttg tgtcctatat gccggaagtc
      241 tataaaatat ctatggttag aatgtagatg agaggtctac tgacgaatcc ttgaatgtac
      301 aggtctatat cggggctgga tagaaatgtc cagtgacaca aacagtgtcg ctactgtggg
      361 tgagtaagac tccgcattta tgaaaatcca tataacgtta aaggcgttat caaggtagca
      421 ggcttataga ggaaacctaa ggatatatgt acagatagtg tgtttggaac gttgaaagct
      481 gacaacatgg agattttact gtctgtgaag tgttcacatc agaaagttat tgtgagatta
      541 gcaatgatat aaggtgtgtt aatgtcagtg agagtggtgg cacagtacct atgaaaccgt
      601 gataacaagc ggtggaggga tagccactag tcatatgaag aatagaatta ctaagaaaaa
      661 tggtatgggt tcgagtaaga ctaagagatg tacttgctcc tgcaaacaag gagggtacag
      721 accatgctaa agaaaaacaa gctccgctat aacgagtatt atgatatgca acatatttat
      781 gacgagttat acgcacagag caagaacggt aataactttt ataagttact tgaaattatt
      841 ggttcggaac aaaatatttg tttagcttac cgtaatctga aatcaaacag tggcagtaaa
      901 acggctggaa cggatggaat gacgatagac gatataaaac aactcagcaa tgctgagatt
      961 gttgctaccg ttcgggaaag ccttagcaac taccgcccca aatcagtcag acgtgttttc
     1021 attccaaaag ctgggagcga taaaatgcgt ccattgggga ttccgtgtat ctgggacagg
     1081 ctggtacaac aatgtatcct gcaagtccta gagccgatat gcgaaccaaa gttccataat
     1141 cattcctatg gattccgtgc gaatcgaagt gcccaccatg cagtcagcag agtaacgaca
     1201 ctgataaatt tatcaaaata tcattactgt gttgacgtag acattaaagg atttttcgat
     1261 aatgtcaatc atggaaaact attaaaacaa atctggacac ttggtattcg ggataaaaga
     1321 ttgatttgca ttatcagcaa aatgctgaaa gccgaaattg acggcgaggg tgtcccagaa
     1381 aaaggaacgc cacaaggcgg tctgttaagt ccactgctct ccctcatagt ccttaatgaa
     1441 ttagactggt gggtaagcag tcagtgggaa acattccagc cgaagaaccg cagtaaaaat
     1501 gggtggcttc aatacgcaaa gaaatatacc aaactgaaaa gcggttttat tgtacgttac
     1561 gctgatgatt ttaaaatcat gtgttcaacc tatggagaag cacaaagatt ttaccacagt
     1621 accgtagatt ttcttaataa aaggctgaaa ttagaaatca gtccagagaa atcaaaggta
     1681 gtaaatctga agaaaaattc atcagatttt ctggggttca aaatcaaagt cattccaaaa
     1741 ggaagaacga aacacggtta tgttgccaaa acagatatga accaaaaagc attaaagaaa
     1801 gcgaaaacaa atctaaagtt aaaggtaaaa gatatagcca gacatacgac tggcttcaat
     1861 atcagcagat ataatctgac agttatcggt atgcagaatt actactgcat agcaactaac
     1921 gtatataaca acctgacaga agtaagttac gctctcttac cgaccatacg aatccgttta
     1981 aggaacattg caaaatcagt tccatttgaa agtacaagtt cagaatttca gagcaggaca
     2041 aaaggaatca gaccaaaaac aaaaatagtg atgattgcgg ataatccgct attgccgatt
     2101 caaggagtac aacacaaaaa tcctatgaat ttctcgcaag atatttgtaa ttttacaaag
     2161 caagggagaa acaaggtgca tgaggacgtt gtagttgtaa caaaagaaga aatccgagcg
     2221 ttgttggaaa atgaaaaccc tgccgatagc gtagagttta acgacaatcg tatttcggca
     2281 tatatcgcac aacaaggcaa ctgctatgta atgaatcgtc gaggaactcc gtccactctg
     2341 atatgtattc acaaatcaga caaaggagat aaccttgaca gatattctaa tctggcattt
     2401 gtggaaattc ccattgcaaa ggcaatccta acagaatcag cagacgaagc aaaatcactg
     2461 ttaaaaggtt atgttcttaa tagtcagcag aagaaaaaac tgaacagaat acggacgaat
     2521 tacggatacc agacaataac tgggaaataa cttataaatc tatttggata tgatggaacg
     2581 ccgtatgaag cgaaagtttc atgtacggtg tgaagcgggg gaaaacttgg agataacatc
//
LOCUS       DAJSMK010000156         2614 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.165, whole genome shotgun sequence.
ACCESSION   DAJSMK010000156 DAJSMK010000000
VERSION     DAJSMK010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.165"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            194..566
                     /locus_tag="ON488_002604"
                     /pseudo
     CDS             194..566
                     /locus_tag="ON488_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
     gene            complement(673..1835)
                     /locus_tag="ON488_002605"
     CDS             complement(join(673..1559,1559..1835))
                     /locus_tag="ON488_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCR3232730.1"
                     /translation="MSRRQRRTYSKEFKQQIVDLYLAGKPRAEIIREYELTPSSFDKW
                     MKQAQSTGSFKERDNLTPEQAELIALRKKNKQLEMENDILKQAALIFGPKRQVIDANK
                     HKYSISAMCKILNISRQTYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAK
                     CGLQFSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQPLEAIV
                     TDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFH
                     TDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFETLA
                     QLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
     gene            2110..>2614
                     /locus_tag="ON488_002606"
     CDS             2110..>2614
                     /locus_tag="ON488_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232731.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIF"
BASE COUNT          865 a          437 c          498 g          814 t
ORIGIN      
        1 aaaaaaatac atcagaagaa aaaaatctaa aattataaaa tgtgatactc atactaaaat
       61 aggagtttca agtgatggaa aatacgattg ctatttaagc acaaatagcg gagctgaaag
      121 taatcttctg gatgaattaa aaagaactga gattcaaatt atagataaaa aagaacgtcc
      181 taaaaatggt tttgtgctat cagaaaaaac tgatttagaa aatacagaag catttaacaa
      241 agaatcggtt aaagatttac gtaaactacc aacaaaggac ataaatggca aggattttac
      301 aagtaaagat tttgagaagt atgatcttac tatggtaaat gtatttgcaa cttggtgtac
      361 agcttgtgta aaggaaattc ctgatttggt tgaggttcag aatgaaatga aaagcaaggg
      421 tgtaaatatc gttggagttg ttacagatcc tgttgatgat aacggtgaaa acaaggaagc
      481 aattgaaaag tcaaagttaa tacatgaaaa gacaaaggct tcatatcctt tcttaatgcc
      541 agatggaatg gcaacacttt ttttgacaaa aattataagg tgttgtgaat gctgcggtgt
      601 tatggctacg attgcccttg acaatgagca tcctcggatc tgattttctc cggcagaagc
      661 acaatcattc aattacgctg cctctccaga ggtatcagat ccgcgctcat tatcaaggat
      721 tcgcttcgcc aatctctgtt gtcgaatttg gatcggtgtt tcatacgcca acgtgccatg
      781 taagcgtaga tagttccacc aatgcacata atcaaacaat tctagacgta gctgtgccag
      841 tgtctcaaat tggtattgat gcacgaattc tactttgaca gatttatagg ttgattccac
      901 aacggcatta tcatacggac aacccttcct actcaatgaa cgagtaattc caaaaccatt
      961 cagaatctca tgaatggttt ggttatcaaa ttcctttccc cggtctgtat gaaaaagctt
     1021 gacgtctgtt aaagaatacg gtatccgtcc aaaggcttct tttaccaatg aggcatcttt
     1081 cttctcacca caggaataac caataatttc tcgattaaac aaatcaagta ttaagcagat
     1141 ataatgccac tttttcccca cgcgaacata agtaagatcc gtaacgatgg cttccaatgg
     1201 ctgttcttgt gtaaaggtcc gatctaatac attcgctgtt ttcgcttcat tacaagctgt
     1261 tcgttgccct ttaaaatgag cgatcgtata ggtagatgtc aatccgcggc gtttcatgat
     1321 tcgaccgatc cggcgccgac tgaattgaag cccacacttt gctaaacact tcttcaattt
     1381 tcgggtaccg taagcctttc ggtttcgaat aaactcttcc tgaacgatct cttctaagtc
     1441 ggactcattt tcgatcggtt tcgcttgata atagtaggtt tgacgagaaa tatttagaat
     1501 tttgcacatc gctgatatgg aatatttatg cttgttggca tcaattactt gtcttttcgt
     1561 ccgaatatca gcgccgcttg ctttaaaata tcattctcca tttcgagttg cttatttttc
     1621 tttcttagtg cgatcaattc tgcttgttct ggtgttaagt tgtctctttc tttgaatgag
     1681 cccgttgatt gtgcttgctt catccattta tcgaaagaag aaggcgtaag ctcatactct
     1741 cgaataattt ctgcgcgagg cttaccagcg agatagagat cgacgatttg ttgtttgaat
     1801 tcttttgaat aggttcttcg ttgacgtctt gacatgaaaa atcctccagt gtgtttttta
     1861 ttattctaca caccttattt tttctgtcta gtctagtgta gccgattcaa attgatgaag
     1921 cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact tactgtgctt
     1981 gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc ataatactta
     2041 tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt ttcataaaag
     2101 gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa taaaggagga
     2161 ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt atgtttgagc
     2221 ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga aggacaatcc
     2281 ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga aacttttaag
     2341 ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt agggcttaaa
     2401 tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc gatgttagat
     2461 gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga gaaaatgaca
     2521 gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa ttggcaaaat
     2581 gagcttgaaa gaattgggac tattggtata tttg
//
LOCUS       DAJSMK010000157         2554 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.166, whole genome shotgun sequence.
ACCESSION   DAJSMK010000157 DAJSMK010000000
VERSION     DAJSMK010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.166"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(135..908)
                     /locus_tag="ON488_002607"
     CDS             complement(135..908)
                     /locus_tag="ON488_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HCR3232732.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(905..1810)
                     /locus_tag="ON488_002608"
     CDS             complement(905..1810)
                     /locus_tag="ON488_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3232733.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(1964..2284)
                     /locus_tag="ON488_002609"
     CDS             complement(1964..2284)
                     /locus_tag="ON488_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HCR3232734.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
BASE COUNT          824 a          495 c          452 g          783 t
ORIGIN      
        1 caaaaacata ctaggaaagg agctgtgaca caaatgttgt cacagctcct ttttcagaat
       61 aaacggtgtt taagagacag ccaatcggca ataaggctga acgtctcttt cacagcctct
      121 tttttgatga gtcatcatac attttttcgc ttaaatacga gatatcctaa tgctaagaac
      181 aaaacgatgt aagctaaatt accgaatagc atttgattag tagaaagatg agtcaattgc
      241 ttcatgatct cttcgtttcc aatttggttt tgcagattca acatactgat cggattccat
      301 ttgatccact cccatttttg gatgagtgca ataaggatac cagatatgat tgacgaagca
      361 aaataaaaga cgattcctgc tgagatggat gcgccggaac tattgataaa gcaagcaatc
      421 atcaacacta aacttaaaat cagccataaa ccgatataac tacccaaagt ataagtgaac
      481 aagctttgga tcagtgtttg accagtagaa accttctccg tgaaggaaat cgaagggaaa
      541 agaatcagtt tcatcaacac agtgacaata atagctaaaa ggtataaata aacagaataa
      601 ataactaatg tgatccattt gcttactaat atttctcctc gagaatactt tcgataaagg
      661 agatttttca atgtaccata ttgtgcttcc atcgaaatga tcgtgcttgc agctgcaatc
      721 atgataaaga caatccaaga tgtggcacta aaaagctgag cagtcatttc aactggatca
      781 atgatcgtcg tgtatttttt ggctagaagt gctgttccta tgagcaaaac aactaataga
      841 acagataaaa cagcagttga ctttttcttg atcaatttaa ataattcttg ttttacaagc
      901 aatgtcattt ttcttcttcc ccctttactg aatccagaat ttccaataga gaagattcca
      961 aatcattcgt cagatgctgg acgtctgtca catggatatt ttgtgcagac aatagctgga
     1021 tcacggttcc taataattct tcgttttctt ttaaaagctt gattttatca ggatcttcca
     1081 aagtatatcc agcttctgtc aagatcgttc gagcagctag atcatttgtt gtagagataa
     1141 cgatgaaatc ttgcgctgtt tggttcaatt cagccattgt acattgtttg atgatctttc
     1201 cttgattgat caggatcagc tcatcgacca ttttttcaag ctcgctgagt aagtgactgg
     1261 agatcaagaa agaggtgccc tgagtagcca agtcggtaat gatttttcgc acatctcttg
     1321 ttgcttgtgg atccaaaccg ttcatcggct catctaaaat aacgatagac ggatggttca
     1381 gtaaggcaag agcaattccc aatttttgtt tcattcccaa cgagtaggat ttcgcttttt
     1441 tgtgaatgta cttttccatc ttgagctgat tcacgatagt gtcgatagca gatacatcgt
     1501 tggtttcaga gaataacttc agatgatcat agcctgttaa gaatggatag atacccgggt
     1561 attcgatcaa tgctcctact tgttccaacc ctttatgact agagggagaa atctcatttt
     1621 caccaataca gattgttcca tctgagtaat ggatcagtcc taaaatagct ttcatgatcg
     1681 ttgtttttcc agcgccatta ggacctacta atccaacgat tttgccaggg gataagctaa
     1741 aactgacatc gctgagggct tgtttgtgac caaagttctt ggataattct tggaccgaaa
     1801 gacttttcaa aaatattcac tccttttcta tagatagtac aagcatacac ctgatgagtg
     1861 gagaagtcgc taggtcattg gacttatttc ttattttttc ataaaaaaat tgaatattaa
     1921 ataaaaaggc ttattttttc tgatcagtac ttattccaag tgtctagtgg ccgctagtaa
     1981 tcttgatgcc aatgatactg atgagtagca tccccacaaa gaaccaagtg gaaagattca
     2041 gcttatcatg aaacaagacc acaccaatta tgaccgaacc aactgcgcca atccctgtcc
     2101 agataggata agagagactc atcggcaaac ttttgattgc ctttgacaaa aagtaaaaac
     2161 tagcaatcat gccaatcact gtgtaaaaag aataattgat tttagaaaaa ccatcactcc
     2221 atttcatcat cgttgaccag aatacttcca aaattcctgc tatgattaat tccatccatg
     2281 ccatacttac attcctcctt aactataaaa aaatacacaa aaagaggaaa atcatccctt
     2341 caaagaccta atggaatgat catcctcttt atcctacccg gtggcagatt gtatatcttt
     2401 ttctgtagta tagcacacct atccagatat cggcaatctc atacttttta gtaaagtgta
     2461 ccaagcactg acggatatat cgttagcgga aaagaagatg aatgctttgc aatttcatag
     2521 aaagaagttg ttatttatta atcatttaaa aaaa
//
LOCUS       DAJSMK010000158         2490 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.167, whole genome shotgun sequence.
ACCESSION   DAJSMK010000158 DAJSMK010000000
VERSION     DAJSMK010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.167"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(931..1449)
                     /locus_tag="ON488_002610"
     CDS             complement(931..1449)
                     /locus_tag="ON488_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HCR3232735.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT          811 a          455 c          358 g          866 t
ORIGIN      
        1 acccctatac tactagtttg taagttagat taataaaaat actaaagtta tttgttcttt
       61 tattaaatac acctacaact tataaattga tggtatttag ataacacgaa agaataaaaa
      121 taacagctga tagtaaagtt tgttgacgat tgctactcaa tcgaaagtga gttagtgcgt
      181 atgaacttgc ttctgaaaac ttatgaaatg aaagaccttt tacatcttgc agaaatcgtt
      241 actgggatta aactaagcaa taaaaactaa tgttcccctc attctttgaa cttctactat
      301 ttgatttatt tattctgata aatgacgatt tcaccttcag gatcttcaaa tcccgtatag
      361 aatttattta agatctcttc agtatcagta ataggatagg cgataggcca catacccttt
      421 gatggttaga ataaactgct caaaatctgt atcgtatgtt ggctttagca tattaacaaa
      481 ggctatctcc aaattataaa ccataagcgt tgaatcgttc ttaacaattt caattcttcc
      541 taacccaaag tcagaagata taattaccgg acttgcctta cccttcatgt gggttgttga
      601 gattccatat ttaaagggaa ttgtcggtac tatcggcggt ctgaaaaaca tcccaaaaat
      661 aaaaaaatct ttcccctgct agtctcctaa gtccctttgt agcggatatg gcaccataat
      721 ctcattttat cgaagtgagt catggtttat ctgttggcca accaaaattg atacaatcta
      781 acgatgcacc ctctacggca ttctagggga gtgcacttgc attcacccaa taaaaaccgg
      841 cagttagcaa agaacttatg tagtcgtatg ttcttactgt taacatacaa gaggtctcct
      901 ttccacaatt gcttagcagt aaacgggaat ttacaaagct aatctcttcc attttcttat
      961 ctttgttcta aaagtcccaa atggagcaac tgtatttaca tgaataaatt tatatacttc
     1021 ccatacagcc gttttggttg cctcgtctgc ccattttctt ttgtgtgcag tgaatagatc
     1081 ttcatcactc attgaatcaa tcatcatgtt aatatcatca atattacgat tgagaatttc
     1141 ctctaattct ttcaatggta gatgtgcata ggtatttgta aaccacttat ataactctcc
     1201 taactgattc catttaaatt gatcagaagg cgttttaaca gataatccat ttctttcatc
     1261 attttcccat tttagaatta aattcgtcca accaacttga tatgctaaat tttcagcagg
     1321 tgttctatcc acttcctcaa ctcttttatc cttcaattct tcaggaatag tttcaaattc
     1381 taaaatatat ttagtataag tcctatttat ttcttttttt aattcttctt tatttttata
     1441 tgttctcatt atattacctc cataaattcc taattgtctc ctttaattca tctataattt
     1501 catccacgat attttaatcc gttctacaat gcatatctga tatgcattga ctgtctaact
     1561 catatgtgaa tgatttataa aatatcccaa cgtctcatct aaagaaatgt tgatcgtcag
     1621 caaggagcta aaaaatacga atatatttct tttgtagtaa aatcggactg gtttgcatat
     1681 cattttcttc gtaaatatca aaatcatgtt aactactatc aattactaat aaaaactacc
     1741 actttaagcg ttaagaactg ttaagtttag ttaagtgagg atagttcaca aaatccattg
     1801 ttaaacttca cgaaagtggt aaaactcaaa atgctttata taggattaca gcatcgctct
     1861 ttcttcgatt gcgcgttggg taaaaaatat tatgaagtaa aaattgacga tgacacgttc
     1921 cttacggctc atcagatgaa acagctacaa aaacgaaatg atcaactcga agaaaattta
     1981 attctaaaaa agcgattgcc atattcacgc ctcgctcgac gaactattaa aggtcaagat
     2041 ttacctgaag atcatccttt ttaggaaatt gaagcttttt atgttgcaca atgcatttat
     2101 aatactacaa tgatgttttc accagatatt cttctagggt gcggtgtaat gaaacagata
     2161 cacttgcaaa agaaaattca ccgcgaattt actaaaatta tgaataatta tgttaatctt
     2221 ccgaaatttt tttccaaaat taagggatca agctggtgtt atagattgtt taaggttggc
     2281 aaaaaaataa cttcttttta aacaattata gaaaaccgat actctgttaa gttggttgac
     2341 acggtgtcga tttttatgac tttcttattc tgaaacttca ctaacggaca gtacctaaaa
     2401 agtctatagt atggacgttt acgagtacta ttttatcaaa aatgctgctc atttcaactt
     2461 atatgtttta gtgaactacc cccacttagc
//
LOCUS       DAJSMK010000159         2483 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.168, whole genome shotgun sequence.
ACCESSION   DAJSMK010000159 DAJSMK010000000
VERSION     DAJSMK010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.168"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(1014..1304)
                     /locus_tag="ON488_002611"
     CDS             complement(1014..1304)
                     /locus_tag="ON488_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232736.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2203)
                     /locus_tag="ON488_002612"
                     /pseudo
     CDS             complement(1512..2203)
                     /locus_tag="ON488_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          734 a          458 c          348 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgatttct acatttgttt
     1681 tttcttgtgt cagtgttgcg atttgttgat tcaaaccatt tacagtattt tgtaattctg
     1741 aaagttttgc ttgtgcttct tgtagtcttg ctgtccaatc tgcattcaga tgattgattt
     1801 catcattttt ttggttgatc tcatctagtt tgacattgat ttcattttgt ttgctttgta
     1861 gttgtgcatc cttgctgact aattgacttt ctaagttttg tttttctgct gccgattgat
     1921 ttttttggtt ttctaattca tttacttttg tttggtattc ttggacatct gcctttgaat
     1981 cttgcaatgt ctgttctttt tgtgctagtc gagcggtaag atctgtaatc gcttgctctt
     2041 tatctgtcaa tgtatgatca agctgtgtca gattctcatt gattgtatca atatctgtct
     2101 ctccacccca caaaataatt tcatttgcgt accgcgtgcc tgtgtagcca attagacata
     2161 gaaatgcaac gacaatccca ccagtaataa atttcttttt catttgcata gctccttaat
     2221 ccaatacttt tacatgctaa aagtaagtga tctcaaacac aatgtcaagc gtttttaaat
     2281 tacatatgta attttaatat aaatactatc aaatactcat ttaatcctcc ttttttatct
     2341 atttaaaaaa tcttttttat agagaaaaat gcaggttaat actttcttaa ataaatattt
     2401 atggtgaaca aaaacaaaaa agcaagtttt attaaacgta acccttttca tttcatagat
     2461 tactgtattt attacaaaaa acg
//
LOCUS       DAJSMK010000160         2398 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.169, whole genome shotgun sequence.
ACCESSION   DAJSMK010000160 DAJSMK010000000
VERSION     DAJSMK010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.169"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            207..2069
                     /locus_tag="ON488_002613"
     CDS             207..2069
                     /locus_tag="ON488_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3232737.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2398
                     /locus_tag="ON488_002614"
     CDS             2069..>2398
                     /locus_tag="ON488_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3232738.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          865 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataat
//
LOCUS       DAJSMK010000161         2395 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.170, whole genome shotgun sequence.
ACCESSION   DAJSMK010000161 DAJSMK010000000
VERSION     DAJSMK010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.170"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            316..570
                     /locus_tag="ON488_002615"
     CDS             316..570
                     /locus_tag="ON488_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCR3232739.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="ON488_002616"
     CDS             571..888
                     /locus_tag="ON488_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCR3232740.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1447..2382
                     /locus_tag="ON488_002617"
     CDS             1447..2382
                     /locus_tag="ON488_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232741.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          861 a          339 c          453 g          742 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 ggcaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaaccgt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacatc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatatatt
     1501 actactttca aaagattatc cgagttaatg cagcagactg ttaaaagtgc tatgcctgaa
     1561 ggatacaagt ttaattttgt tcaatcttca gtatctactg aaagtatcta tttttcaatt
     1621 ctttctgaga gtaggctttt tcattttaga ataagttctc atgtaaagaa aactgatgtt
     1681 gatatatata cgttccgtac aaataattat aaaaatttaa atgatttgag tagaagtatc
     1741 agtgaatatc tcaaggggaa tagctatctc aagattcgat tttcacatat attaatttta
     1801 ctaccatatt tgaatgagaa tttcacccta attcaagtag ataagtcttt cattgcctca
     1861 ggtaatcaag gaaatatgaa tattacaagt aacaaaacgt cacgtgtgct attggcgttg
     1921 atgggttacg gaattcttta tagagatgac caaaatggcc agattctaat aaatcgggct
     1981 gggcgttcat tattaatgaa atatagaaaa tttataccgg aagattttca aaacttacag
     2041 ttagaaaaca tgcgtttaga agatttattt agattagcag aagatgataa gtatagattt
     2101 gaagttttga aaattcaaaa gaatgaacta ttgaataagt tatatcctga gaatgcgata
     2161 aaagcacatt ttggtgatgc taatcatatg tatagttggt tcattcctaa aagatttaga
     2221 gggaaaatca atgctggaga tcaagtgaaa gtactcaatc gaaatagtac agatgtcgta
     2281 atgataacag atatctatgt agaagatgaa gatataatca aatatatgaa gcctgtgata
     2341 aaacttgtta ataaaaataa aggaacccgt ggtgctagtt aattttttcc tagag
//
LOCUS       DAJSMK010000162         2325 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.171, whole genome shotgun sequence.
ACCESSION   DAJSMK010000162 DAJSMK010000000
VERSION     DAJSMK010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2325
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.171"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..377
                     /locus_tag="ON488_002618"
     CDS             <1..377
                     /locus_tag="ON488_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232742.1"
                     /translation="EWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIVDYFANTP
                     EEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKKKEYNYIV
                     KAKVSKRFIFNPKLEIYSVVIE"
     gene            702..1319
                     /locus_tag="ON488_002619"
     CDS             702..1319
                     /locus_tag="ON488_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232743.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            1360..1659
                     /locus_tag="ON488_002620"
     CDS             1360..1659
                     /locus_tag="ON488_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HCR3232744.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1693..1860
                     /locus_tag="ON488_002621"
     CDS             1693..1860
                     /locus_tag="ON488_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HCR3232745.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(1905..>2325)
                     /locus_tag="ON488_002622"
     CDS             complement(1905..>2325)
                     /locus_tag="ON488_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232746.1"
                     /translation="SLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLD
                     TAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLV
                     FKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          814 a          349 c          442 g          720 t
ORIGIN      
        1 tagaatggaa taatctgact caaaataata aaaataattc tggatgtgga attatcttta
       61 tgtttgttat agttttggga atagtagtac ttttaataac tgtcaagata gtagattact
      121 ttgcgaatac tcctgaagaa caaatacaga gaaaacttcc tgagtttgaa agagtaccac
      181 cttatgatcc aagagataat tcatttcaag taaaaaaatt aaaagagtct ccaaatgaaa
      241 tgtggtttga agttacagtt gaatcaagcg acttcaaaga aaaaaagaaa gaatacaatt
      301 atattgtaaa ggcaaaagta tcaaaaagat ttatttttaa ccctaaatta gaaatatata
      361 gtgttgtaat agaataatag tgttaaaaaa attgtaaaag ttaaagaagt caaattctga
      421 tgtgaaaaat aaaatatacc atggaagaca taaaagaaaa actggataac tagtttattt
      481 aatggcagac cgttaaggcc tgccattttt atgtatttta gcggaataaa tataatcatg
      541 cgggagtgta aacttactgt ttcaaaaagt atactttttg acatgccttg attttctttg
      601 tttatgtatg gcataataac cacataatac aatttgaaac gtttctgatt taatctgatt
      661 gttttgaaac aattttagtg aaaaaagggt agataaaaac gatgagaaaa tttttttata
      721 tccgggtcag tagttatgat caatcgatcg aacgacaact gatttccgcg aaggaattag
      781 gaatccctga agaatatata tttgtagaaa aagccagcgg caaagatttt aaacgccctg
      841 aatatcaatt aatgaaacgg atgtttcgaa aaggagattt actctatcta caatcattag
      901 atagactagg cagaaataaa caaatgattt tagaagaatg gcgagaatta actaaggaaa
      961 agcagattga tatttctgtg ttagacatgc ctctgttaga tactgctagt tacaagcaac
     1021 tagatgggtt agagacgctt atctctgact taattctgca attactcagc tatatggccg
     1081 aagacgagcg gaaacgaatt aatagccggc aaagagaagg cgtagaagct gcgaaacaaa
     1141 agggtgtaaa attcggcaga aagaaaattg ctttacctcc tgaatttcct gcgatctatt
     1201 ctgactggaa agcaggaaag ataactgcag tctatgctat ggatcaattg ggcatgaaac
     1261 gaaatacctt ttatcgacgg gtgaaagaat atgaacatac cttgcaccac ttttcttgat
     1321 agatataaca gctattagac gggaagggag agtttgaaaa tggacttaac gaatcaaagg
     1381 gtcgttttta ctggaacgct gcagcaaatg acacgaaccc aagccatcgg tttggttcac
     1441 tctttaaacg gccattgtca atcaagtgtt acttcaaaaa caaatttcct ggtttgtggt
     1501 cagtattcta agtcgttgtt tgatgattct ctctatacaa aaaaggaaca aaccgcgcgg
     1561 gacttgattg cgttaggtca tgagattacc attttatcag aagtcgaatt ttatgcgtta
     1621 attagtcaac agttgaaaga atggcaacgg tatttataat cgttagtaaa atttacaagg
     1681 aggaaaattt ttatgaagcg aaaatcttat gatcgttggg gcattgaaat aactagtttt
     1741 aatcgaaata ttgcttttca cgtggagtgt gactgtgggg aattagcaaa aagtgtttat
     1801 caaaaaaatt acttttactg tcctaaatgc catcgccgat acggggtaca tggaacatag
     1861 aaacgaaata gtgcggtaga aaagcgaatg aatgtagtat atttctacaa atcattcgct
     1921 ttctttattt tataaatagt tggtcgagag atcccgtttt cttttgcaat ctctgcaact
     1981 ggaatgcctt gctttaacat gtccaccacg gttttaaaaa ctaagcgttt ttgcggatct
     2041 gttgagttaa tagaatactc gattggtcgt cccttatatc ggccggcttt ttgagccaat
     2101 aatactcctt gccgctgacg ttcacgaatt ttctcacgct cgttttgtgc aatataactt
     2161 agcagtgata aaaacatatc gaacatagcg gtatccagga gttcatttcc agtattaaaa
     2221 tctaaaaact gtgcatctaa tatttttaac gctacttttt tctgtttcat aaaagcaact
     2281 gtatttttta tatcttcata atctcttcct aaacgatcta gtgat
//
LOCUS       DAJSMK010000163         2183 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.172, whole genome shotgun sequence.
ACCESSION   DAJSMK010000163 DAJSMK010000000
VERSION     DAJSMK010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.172"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..345
                     /locus_tag="ON488_002623"
     CDS             <1..345
                     /locus_tag="ON488_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HCR3232747.1"
                     /translation="NKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDA
                     PIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKK
                     LKKVNKMNLEVE"
     gene            345..1721
                     /locus_tag="ON488_002624"
     CDS             345..1721
                     /locus_tag="ON488_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232748.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            1851..>2183
                     /locus_tag="ON488_002625"
     CDS             1851..>2183
                     /locus_tag="ON488_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCR3232749.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT          850 a          270 c          400 g          663 t
ORIGIN      
        1 aataaatcag cagatgaaag tatcttgttt gaactaggtt tagataaaaa acaaataaaa
       61 agaaatgtta tgaaattatc tggtggacag caacaaagag tagctattgc tagagcattg
      121 gtatcagatg ctccaataat actagctgat gagcctactg gtaatctaga cagtgttact
      181 gctggagaaa taattaatat attaaagaca ttagctaaag atagaaataa atgtgtaata
      241 gttgtaacac atagtaagga agtagcagat tctgcggata tcattttaga actaagtggt
      301 aaaaagttga aaaaagtaaa taaaatgaat ttggaggttg aataatgata aaaaatgcat
      361 ttgcttatgt aactagaaaa agtttaaaat cattaattat catattagtt attttatcta
      421 tgtcaacttt aagtctcatt agtttatcta ttaaagatgc tacggacaga gcttcaaaag
      481 aaacatttgc taatataaca aatagttttt ctatggagat aaatagacaa gtaaatccag
      541 gaacacctag aggtggggga aatgtaaaag gtgaagatat taaaaagata tctcaaacag
      601 atagtataga ctcctatgta aaaagaataa acagtgttgc agatttagtt gattatgata
      661 ttattgaaac tcaagagact cttgcgaatc aatcacctga aagagcaaag aattttaaaa
      721 gaacagttat gttaactggg gttaacgact caacaaaaga aacaaaattt gtatcagaag
      781 catataaatt agtagaagga aagcatttag aaaatgaaga taaaaataaa atcttaatgc
      841 ataaagattt agctgaaaaa aataacctta aagttggaga taagataaaa ataaaatcta
      901 atttatttga tgctgataat gagaaaggtg cagatgaaac agtagaagta gaaattaaag
      961 gtctattcga tgggcataat agcggtgtag taagtgcagc acaagaacta tacgaaaata
     1021 cattaatcac tgatattcat acagctgcta aagtttatgg taataccgaa gatacagctg
     1081 tataccaaga tgcaacattc tttgtaaaag gtgataagaa tcttgatagt gtaataaaag
     1141 atcttgggaa attagatata aattggagag aatataattt gattaaaagt tcatcaaatt
     1201 accctgcatt acaacaatct atatcaggta tttactcaat ttcaaataaa ttattttttg
     1261 gctcattaat atttgcagga gttgtagttt cattattatt attcttatgg atgaatgcta
     1321 gaaagaaaga aatagcagta ttactatcat taggtatatc aaaattagaa atttttggtc
     1381 aattcctaat tgagatggta tttatatcaa tccccgcatt cgttggttcc tatttcttag
     1441 ctcaatatac agctgacaag cttgggaata atatattgaa taaggttact ggtgatatag
     1501 ctaaacaaat agctaaacaa tctgcatcta gccaattagg tggtggggca gaagctgaag
     1561 gatttaacaa gacattatca agtttagata tcaatgtatt acctaaattc atgatttatg
     1621 tagttatatt tatgagttta gtacttcttg tatcattgat tatttcttca ttcaatatat
     1681 taagaaggaa tccaaaagaa ttattaattg acaataatta aaattttcgg tgctttttag
     1741 caccaaaaat gagagtgtaa tataaaccgt gtaagtaacc atcaatccta ggcgggtggt
     1801 tgcttcacgg tttttatttt tctaaaataa gatcaagagg tgattacacg atggctagaa
     1861 agaaaagaaa tcctgatgct gagaagttag ctgaatccat tttgaatact tatcaacccg
     1921 aatctgtaga ggatatgcaa gatgttttaa aagatgtgtt tggtccctta tttgaaaaaa
     1981 tgcttcaagg agaattgaat aaccatttag ggtatgacgc ccattctaaa gagccaaaga
     2041 aacatgacaa tcgacgaaac ggttatggca ataagacgct taaaacgagc tttggtaaag
     2101 taaacattga tgttcccaga gaccgggagg cttcttttga acctgagttg attcctaata
     2161 gaaaacgaga tgtctccgac atc
//
LOCUS       DAJSMK010000164         2167 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.173, whole genome shotgun sequence.
ACCESSION   DAJSMK010000164 DAJSMK010000000
VERSION     DAJSMK010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2167
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.173"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..914)
                     /locus_tag="ON488_002626"
     CDS             complement(<1..914)
                     /locus_tag="ON488_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HCR3232750.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNHTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1342..1905
                     /gene="efp"
                     /locus_tag="ON488_002627"
     CDS             1342..1905
                     /gene="efp"
                     /locus_tag="ON488_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HCR3232751.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2006..>2167
                     /locus_tag="ON488_002628"
     CDS             2006..>2167
                     /locus_tag="ON488_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232752.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFF"
BASE COUNT          736 a          382 c          415 g          634 t
ORIGIN      
        1 aagtaaatgt tttttgataa atagcggtct gctgcgtctg gaaaaatcgt aacgacacga
       61 tgaccaggtg gtaaacgacg aatttctctt aatgctgctg caaaagccgc accactcgaa
      121 cttccaacta atagtccttg ttctcgtgct aactgcctag tatggttaaa cccttctaca
      181 tcagagattg tctcgatctg attgattgaa aggggagaaa gaaacggcgg aatgaattct
      241 acaccgatac cctcaatttc gtgaggggct ggatcaccac catttaacac agagccctct
      301 ggttctacac cgattattcg aatgtcggga tatttttctt tcaaaaaggt agaagttcca
      361 gcaaaggttc caccactccc aattcctgct acaaaactat ggatattttc tttgatttca
      421 tgaaagattt ctggccctaa cgtatgatag taagcagcag gattatcttt attttcaaat
      481 tgaagaggca gatagctgtt tgatatctcc tctgcaagtt ttttactttt gctgatggca
      541 ccgatgattc cttgctcact aggagaatgg atgatctttg ctcccaatgc tttcatcaat
      601 tgttgttttt ctaagctaaa cttctctgga acaacaaaaa ccgttcttaa tttgtatgtg
      661 agtgcggcca gagcgatccc aattcctgta tttccggcag ttggttcgat gatcgtcgtt
      721 ttttcattga tttttccttg ggcaaatcct tctttgatca aataactgcc caatctatct
      781 ttgatacttc ctccaggatt taaatattct agttttgcat aaatagcaga acctttaggc
      841 atagaatagt gctgattgtc aaagcgataa agcggtgtgg aaccaatagc ttctgtaatt
      901 gtcgagataa tcatatgggc ctcctaaaaa aagataataa aaaaaggagc tgactattaa
      961 atcagctcct tgaaagacat agagaaaaat tgagtagata aaaagataag ttacctggta
     1021 ctcattctat gaagggcaat taatagacat gacaaatagt atgctgcttt tatgcaccat
     1081 acaacagcaa cgattcaatt gtttttggtt gctgactgtc atgtgtatcc ctccaagtaa
     1141 aatttttatt aacgatagca tgaaaaaaaa taaaagtcaa aggcttgaaa gaaaaaaata
     1201 tttcgatagc atcgtttacc cgtgtttatt tttctgacaa ataggcatga gaccttaaaa
     1261 gatagagaat actctagttt tctggccggt tgtctgatac aataaagttg attatgataa
     1321 agaaaagaag gagcaaaaat aatgatctca gcaagtgatt taagagccgg tatgactttc
     1381 gtacaagacg gcaaactgat taaagttctg gatgcaagcc accataaacc tggtaaagga
     1441 aatacagtta tgcgtatgaa actgaaagat gtccgttcag gtgcaacata cgacacaacg
     1501 ttcagaccag aagaaaaatt tgaaaaagca catatcgaca caaaacctgt acaatatttg
     1561 tacacgatgg atgatacagc tttcttcatg gatttggaaa catatgagca atatgaaatt
     1621 cctgtagaaa cagtagaaga agaaatgaaa tatatcctag aaaacatgga agtaaaaatc
     1681 caattcttcg gtagcgaagt catcggcgtt caattaccaa caactgtcgt attacgtgtt
     1741 gtggaaacac aaccttccat caaaggtgca acagtcactg gttcaggtaa accagcgaca
     1801 atggaaactg gcttagtagt caatgttcct gacttcatcg aaacagatga attgttggaa
     1861 atcaatacag cagaaggttc ttatgtaaaa cgtgcgtcaa aataattcgc taacggattg
     1921 ataagaattt gaaaacagag cttgacctct tgaaaggcag atcatcggat ctgcctttca
     1981 agaggttttt tgtggaatca gcaaattgaa aaataaaaaa gtatttgatt ttatttatat
     2041 tttgaaagat gaatggcaaa agctagagaa agaaaaaact gcacttattt atgaagaaat
     2101 tgaaatgatt cataaaattg aaaatatccg aactattccg aactatattg aagcgaaaat
     2161 atttttt
//
LOCUS       DAJSMK010000165         2111 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.174, whole genome shotgun sequence.
ACCESSION   DAJSMK010000165 DAJSMK010000000
VERSION     DAJSMK010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2111
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.174"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            724..1056
                     /locus_tag="ON488_002629"
     CDS             724..1056
                     /locus_tag="ON488_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HCR3232753.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1675..2016
                     /locus_tag="ON488_002630"
     CDS             1675..2016
                     /locus_tag="ON488_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HCR3232754.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          742 a          278 c          437 g          654 t
ORIGIN      
        1 ttttaataga atttataagt taaaatatta tgataaaaat cacaaacgta gccttttacg
       61 tcataagtgt taaaagaaat aattaatttc aaatatagaa aagggaacgt atgtttgcat
      121 actccttttt tttgagttat aataatacgc gaagagagat aatttcatta tttaaacaag
      181 ctaaaaatct tgatattact tcttttcagg caatacgaat attattcgct tacatttttt
      241 gtataaattt aattgtctgc tatgcttgtg atgaattgat tttcgttttg cacttttgga
      301 tgataaattt ggacaattga aaatacaaaa aaaagaaagg cggtatgaac tcggaaggct
      361 ggtaaccttc gtcagcgttc atacacggca ttaagatttg gcccttaatg cgttaacctt
      421 tcagtgttac ggtattaccc gcaatggatt tagtataaca gatattcaaa agtgatacca
      481 ctttttttgg ctgtgttaag gttaaaaata cgtgatatta cgatgaatct atgcctaagc
      541 ataatgttat aaaaatgtcc gtgtggctct ttgccgtatg acgaacgctg aaattagagg
      601 gaacgcatgt ttggatgcgt tccctctttt ttgtttgtca tgaacgaaaa tcaattctct
      661 atttttgaaa aataacaaga aaaacttgtt aaaaatattt aaagaaattg ggtggtttat
      721 tttatgtcat atacaggaat tttgagtctc aaagatattt gtcactacgg taaacggtgt
      781 accgctacag agaaaatcac gaagaaacta tcaactggcc aaagtaaaac cgttgtgcag
      841 tgtaagaaat atataatcca gaaagacaaa gtctcagagg aaatgattta ttacattggg
      901 aaacaaaagc aaataatttt aaaagatcct atccccttaa aagagctata tccaacaatc
      961 aaacatgttt atgaccaaaa cggtgtactg attggtcgaa gaaaaaatgg agtcttgcgt
     1021 tgtaccgcaa aagggatggg gcgtttgatc ggctgaattg atcattctca taacttgtat
     1081 tttatcgttt ttcgcttgct tgaaaatatt gtcgagactt ctaaaggaac ttagagtcac
     1141 tagaaaaata aggagtagac ttgatctatc aacaattccc ttcggggagt gacggggtag
     1201 gttttaacga ttggtaacgt aaaaaattgg tcaatcgagt aaatgcgctt gtttggatag
     1261 tggtgaaatg aatttgtgta aataataagc gcagagtaaa caagagggaa tttagaagtt
     1321 agacaagtta gaatagcgtc tagattaatc atgagcagct actaagggat ctagactttg
     1381 acgcaaactc atggaataag gagtaggtct tctcgtaatg gggaggacgc acaagaaatt
     1441 gtgtcgtgtg ctgcagtaca tgtagatact tgcgaggacg ttgattattg gatcaatcga
     1501 gcatttaccg ctgtctacta gggtttctcg tttcggacgc cataaacgag tcgaaatttt
     1561 ttatgtattt ttaagtaaac gaaaaacgat aaaatatgaa caagtcctga ataaagtgaa
     1621 aaaattaata taaagcatag agaaaatgaa atttacgtaa tggaggaatg acaaatgaaa
     1681 aattatgatc cgaatatacg attgggcaca catactatta aggtttcttt ccaacgttgg
     1741 gattacaaag gatttgtgac gtttagaagg ggcggaaatt gtaaaggatt agatgtttta
     1801 gcattagacg aggatgattt atacgatcaa acattgactg ataatccaat tggattcggc
     1861 ttgctacctg aagatgatga aggtaatgaa tggtttaaaa tgacgcttat gaatgataat
     1921 ggagacgaat tatctgttga agatacttgg tcatatttga gtgattatat tgtcagcttt
     1981 gaaatcattg aatttgtagc ggataaagaa gaataaaaac tggaggaata aattttacag
     2041 ataaaggctt agaaggagtc acgacgatta ataaaaaggt agtattacct taggcattga
     2101 gtaaggaatt t
//
LOCUS       DAJSMK010000166         2039 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.175, whole genome shotgun sequence.
ACCESSION   DAJSMK010000166 DAJSMK010000000
VERSION     DAJSMK010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.175"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            51..260
                     /locus_tag="ON488_002631"
     CDS             51..260
                     /locus_tag="ON488_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232755.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="ON488_002632"
                     /pseudo
     CDS             467..667
                     /locus_tag="ON488_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="ON488_002633"
     CDS             complement(1379..1984)
                     /locus_tag="ON488_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232756.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
BASE COUNT          664 a          345 c          360 g          670 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttt
//
LOCUS       DAJSMK010000167         2002 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.176, whole genome shotgun sequence.
ACCESSION   DAJSMK010000167 DAJSMK010000000
VERSION     DAJSMK010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.176"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..378
                     /locus_tag="ON488_002634"
     CDS             <1..378
                     /locus_tag="ON488_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HCR3232757.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="ON488_002635"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="ON488_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HCR3232758.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2002
                     /locus_tag="ON488_002636"
     CDS             1859..>2002
                     /locus_tag="ON488_002636"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232759.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          554 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tt
//
LOCUS       DAJSMK010000168         1979 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.177, whole genome shotgun sequence.
ACCESSION   DAJSMK010000168 DAJSMK010000000
VERSION     DAJSMK010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1979
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.177"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(325..528)
                     /locus_tag="ON488_002637"
     CDS             complement(325..528)
                     /locus_tag="ON488_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232760.1"
                     /translation="MSQLGKCYSLSKSNRKVYTLFISDSVKEGFTLGFSISFKKGTKN
                     TSISHNNRELTDSQKINGLSGRK"
     gene            complement(728..1744)
                     /locus_tag="ON488_002638"
     CDS             complement(728..1744)
                     /locus_tag="ON488_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HCR3232761.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          557 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaca ttttcctaat tgtgacatgg ctgtcacaat
      541 tccaaatgct ctccgagggt attcgctgtc acaagtgaca acgaaaaaag gagccgaaag
      601 cgtgtcacgc tctcaactcc ttttacgctt tattttgctt catgcaaaat attcgcttat
      661 cgtgaattta cgtcactaaa cattgacgca aatccactct cactcatctg acttttctta
      721 ttcggtatca cttctctgtc acatccaacc ccaaaagcca cgtatccaat tcttttttta
      781 attcgtctgc agattcctta aaagtctctc gtaaatgatt cgttaactca tcattttgac
      841 tttcttgctt cagcaaattc cgatatttat attttgtatg tctagcaatt atcgaccaat
      901 tagaaggctc agctatcaaa ccatcaataa ctattttatc aataggtttt atatcaatcg
      961 gcaaaaaatg cgggcttgca aaactatcta agctttcctg aaccatcgca tgccaatccg
     1021 ttgctttgcc acgtcttagc tgcatttcta accgccacca cgtatcgatt tcttttggca
     1081 cgattacttt ttttcgttcc tgctctagct ttttgttgta cagtcgcact tggcgctcac
     1141 tggcacgact gccccagtac gctgtttcta gcttgccaga acggccgtag attggcttaa
     1201 aagaaatcgg gtctacaata cgatactgag taataaagtc atccggcaca tctacaatat
     1261 cgcaggcaat atccgcccgg gaaaaatgcg gatctaaaaa taggtcatga atgaatcctt
     1321 tcatggaact agctaaaaac tggcctatct tattcggatt aaaatcaata cgaccttttc
     1381 cttcatgaaa tttaagtatt tcgatatacg caatatcttc tccatattga tcgaataatt
     1441 gccagccgtt tatcccaact gatttcaaat atccctgatt ttcgttcaaa cgcattaatt
     1501 gctcgaaatc gacaaaaaca actccatttt tcgtccaata agctatggta tcattcagtt
     1561 ttccgacaat tgtaattcga tcaatcgacc aatttaattt taggggggtg gtcgtacctt
     1621 gcacacttaa ccgcctgtta gaaatacggt taagtttttc gagctgattt atcgttgttc
     1681 ttttttctgc ccctcgacct tcaatttttg attgaatttc actcaactga ttttcatttg
     1741 ccattttcgt cctccaaacg aaaaaagaga cttttggaaa gaatttccag agttcacgta
     1801 accctaaaaa ttcatatcca aaaatctcta gcttgaagaa acctaaaaat attcgtataa
     1861 tgaacctgag ttacggagct aggtgaagta gtttccgtaa atagtcgaga gtgttagcgc
     1921 actgctcggc ttttattttg ctcttttttc tcgttttctt tgattatagc actcctcct
//
LOCUS       DAJSMK010000169         1959 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.178, whole genome shotgun sequence.
ACCESSION   DAJSMK010000169 DAJSMK010000000
VERSION     DAJSMK010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.178"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(373..594)
                     /locus_tag="ON488_002639"
     CDS             complement(373..594)
                     /locus_tag="ON488_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232762.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(692..937)
                     /locus_tag="ON488_002640"
     CDS             complement(692..937)
                     /locus_tag="ON488_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232763.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
     gene            1177..1791
                     /locus_tag="ON488_002641"
                     /pseudo
     CDS             1177..1791
                     /locus_tag="ON488_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
BASE COUNT          647 a          345 c          287 g          680 t
ORIGIN      
        1 agcgacaata atgacgtctt ttttgaattg tttgccttta aaatgattca ttactctgtc
       61 ctctctgtct tttttctcaa ttttacacta aaatagattt tttggaaaac tttgcaacag
      121 aaccgttttt actatatact tcttcccaga acttgtccgt ctccttcaaa ttatctctac
      181 ctctcgagtt cattgggtgg tttgcccatt tattaaacat ggaatcacct ttctcatact
      241 catatattta tgtcctattt caattatatt tatatatgct taaataaatt tgtatcctga
      301 aatttattgt aatatgaagc tgtattttac atatagtaac caaagagtta ataaaataaa
      361 aagagcgaac cattatagat cagctctttt ttcattgctg tttttaatct tatctagaat
      421 cacttcaaat gtttcaaagg tatttacatc taactgacat aaccaaagca agtacttctt
      481 ttctttgtaa gtccaatcaa tattacggta agaggacatt agattatggt accttgctct
      541 ttgttcaact gaagccaatt cccagcgttt ttcaaatatt ttttcttctt ccattattga
      601 tccctcgcaa gacgctacct caaacttaaa taatgggcag cgaaagtcta attccttaga
      661 tctaagtata gcaaacaaat atgaaaaaaa cttagaaggt agtaaaagtt cttccgtctt
      721 ttgctttgct tctattctta atgtgtttcg ttatcggtgc cctacaaaga ttttcattaa
      781 ttacacactc atttattgtt gtgtattttc tgacatttct ctcttgatca attattttaa
      841 ttccatgggc atcctgatag ttcataggag aggagcggct atcagaaata gttgcaccta
      901 tctcttgaac ttcttttaca acttctggaa aatccatcca tcctgcttca gctgtcaaaa
      961 gtaataatct ataatattta tctttccttt tcaatctaag aaatcgtcac cccattcttt
     1021 ttcttctatt ataaactatt taacttttag aattcaaaaa ccgtttgtct atttagagtt
     1081 taccctaaat agacaaaaat ataacattga aaaatttaga gttctaacgt atgattaggg
     1141 tgtattataa acgttataga aaagtaggga ataaatttga aaattgctta tattagagtt
     1201 tcatccatcg atcaaaatga acaacgtcaa attgaagaaa tgaaaaagtt tggcgctgaa
     1261 aaaattttta tcgaaaaaca atctggagcg acgattagtc atcggccgat tttccaggaa
     1321 gctttagatt ttgtcagaga gcaagatatt tttattgtag aagccattga tcgacttgga
     1381 cgcaattatg acgagattat cgattcagtg aattatctaa agaagaagaa tgtgcgactt
     1441 attatcacca gtttaccgat catggctgaa gcaattggaa atcctctcct agataaattc
     1501 atcaaagact taatcattta aatctcagcc atgattgctg aacaagaacg tactgaatcg
     1561 aaacgacgcc aggcacaagg aattaaaatc gctaaagcaa acggcgtcta taaaggtcgt
     1621 cctaagttat acagtgcaga caccaaagat cctcaacgtc gccttgtcta taggagtatc
     1681 gttcaggatc ttgagaatgg ggttgctatc tcaaagattg caacagacta caatgtgact
     1741 aggcaaacaa tttaccgaat aaaaaaagaa atcgaccaac taattgtatg atttcttttt
     1801 tgaatcacgt aattattaat tagctttgtc atcaatacag acaatcattt tagattcatc
     1861 tagctaagtt gattacattt atgttaaaaa gaatttagtt aacataaata taattgatgc
     1921 ataaatcgtc cttatttaaa ggcatttaac attgacaac
//
LOCUS       DAJSMK010000170         1908 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.181, whole genome shotgun sequence.
ACCESSION   DAJSMK010000170 DAJSMK010000000
VERSION     DAJSMK010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.181"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            289..885
                     /locus_tag="ON488_002642"
     CDS             289..885
                     /locus_tag="ON488_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCR3232764.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(943..1425)
                     /locus_tag="ON488_002643"
     CDS             complement(943..1425)
                     /locus_tag="ON488_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232765.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1531..1728)
                     /locus_tag="ON488_002644"
     CDS             complement(1531..1728)
                     /locus_tag="ON488_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232766.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
BASE COUNT          657 a          370 c          286 g          595 t
ORIGIN      
        1 tataaaagca agtaattttt aatggcaata tcataaaaaa aagaagatag agatttaata
       61 attatatatc agctgttttt ttcaaataag caaaaattcc taaaacacaa caatgaaagc
      121 gataactaag aaaatcctta cataacgatt tttcttatta aaattgtttt ttgaacttcg
      181 cttatttttt gtgagcatat ctgtttactt actttttgta aggtgctata cttcatttcg
      241 taatcaatta aaaaaatgca aaacgcaaat caaaggagaa attttattat gacaactttt
      301 actgacactt tgaaaaaccg ccgttcaatc tatcatctag gacgtaatgt ttcactttct
      361 aatgaagaat taacaacttt gatcaaagaa gcaattaaag aaagcccaac tgctttcaat
      421 gctcaatcaa cacgcgcagt tatccttttc ggagatgcac atgaaaaact ttgggaaatc
      481 actgaagaag cacttcgccc attgactcca gcagaagctt tcccaaatac acaaaacaaa
      541 ttagctggtt tcaaaaatgg ttatggtaca gtattattct tcaaagatac tgacgtggta
      601 aaaggtctac aagaacaatt tgaattatat gcagacaact tcccagattg gtcagaacaa
      661 tcaaacggaa tcgcaacagc taatacttgg gtagcattag ttgataaagg attgggcgca
      721 aacttgcaac attacaaccc agttattgac gaagcagttg caaaagaatg gaatatccct
      781 tcaaactgga aactacgttc gcaattagta ttcggttcac cagaaacacc ggctggggaa
      841 aaagaataca tgaacgatgc cgatcgcttc cgcgtatttg gataatttta tttgaaataa
      901 aaaacagagg ttgtgacaaa catcttgtcg caacctctgt ttttattctg gatcaatcat
      961 aatatcaatc tctgcctcat cgtttaagcg ttgggacaaa aatggaacta attcttctaa
     1021 tgatgcagaa aatttcagca tcggtcctcg ccatccgttt cggaaaaaat tcatttttac
     1081 gattttagaa ccttttggct gatataatac aattttattg atctcagaaa aaggaacacc
     1141 ttttttgtca aagctattca aaacaagtcc ttcttctgtg attcctctac tgtccaacaa
     1201 aaaactaata aaaatcattg ctgacaagat cccttttgcc aattcatctg ctgtaggatg
     1261 actgatgagt gtataccaaa tgactagtga cactaagaag ggtatcacca agtagaccca
     1321 tcgatttcgc acagtccgat aaataatttc ttttcgaacc agccaaagaa ataaaaacat
     1381 cacaacaacg aataaaaaca atagaaccgt aaagaatgtt accatgacaa ctcgcctcgc
     1441 tttttcttct ccagaaaata ggaaaagaat actgatttac cttctcaaag aaattggact
     1501 tgcagcacgc cgcacgtcca attgttttct ttattcaaat gtatcatatt ttgcaacaac
     1561 catgcttgct ttttcatcta ataattcttg gtcctctgca gcacattggg caactttgac
     1621 cacggcgcag tttgtcattt ttgatacaac ttcaccaatg accgtttttg taaaaccaat
     1681 tggtttgcat gcatattgtt ctcctaaatt aatcatttct tccgtcatca aaatcctcct
     1741 aaactgctgg aacttttctc cacattacca ctgctatttc tttggagatt taactcattg
     1801 atttttattt acagttaaaa atcaacctta caggcattat agcgtactgt tttcgttttc
     1861 acaattaaaa cagctgttgt atttagaaga atttttttca aaaaatta
//
LOCUS       DAJSMK010000171         1892 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.182, whole genome shotgun sequence.
ACCESSION   DAJSMK010000171 DAJSMK010000000
VERSION     DAJSMK010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.182"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..561)
                     /locus_tag="ON488_002645"
     CDS             complement(<1..561)
                     /locus_tag="ON488_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HCR3232767.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(748..1398)
                     /locus_tag="ON488_002646"
     CDS             complement(748..1398)
                     /locus_tag="ON488_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232768.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
BASE COUNT          677 a          374 c          228 g          613 t
ORIGIN      
        1 tataaacatc accccaaata aaacagaaaa cagtataagc attataaaaa ttatcaacaa
       61 ccttgatcct tcttttatag attcaggaaa cagtataatt ttagtactag ataaattgtt
      121 tacaccgatt agtgttaaaa tatctttatt cttcttgcta acataaccct ttatgcacaa
      181 aagaacagct atacttaaag taacaaataa ataacgtatt ccaatagaaa aatcactata
      241 aatactctct agcataggac cgacaattga agaagtcact actgcaaatg ctggacctat
      301 ccaagcaaca ttagaatgtt ctttctctct tttcctttgt aaatctttgt tgagtattaa
      361 tctatttatt tcttctgcag gcaagttaat tttcataacc ttatggggga ttatccaatt
      421 aaaaatcgga aaaaggtagc ctccccaaaa agtatagtga tctgtgtcaa tcagataata
      481 acctgatttt gattccagaa taacatatct caaagccgaa cgaaaatttt tcatgaatat
      541 ccataatctc actgtttcca cacctaattc ctccaattcc aattaaatgg atttatagca
      601 tcaccaatta tgttaactgc ctgaccaacc tcattgataa aattggcacc actatcccat
      661 gcttcaacaa tgctatatat ctatcaaaca aaaaatggaa aactaaatac tcgcgcacat
      721 aaattttaca ttctgttttt tataagacta ataataatca ttgaaaaaat ttcttatcgg
      781 tggcgcatat tcccaattga ttaatgtgat cccatattct gcaagtattt tacgagcttc
      841 ttctaagtca tagtgagaaa aatgcataaa acctgcaata cgatcacgga ctgtgagctg
      901 tggcttgctt ccaccatcat tcataaaata tccagcagag ccactactta aagtgattgt
      961 tacatcttca ctttctatta ttaagaattc ataatgaaat gctttcaact ctccactatt
     1021 atttaaaagt tttatactcc aacttcgtct aggttgagtt gtcacattcc ctctaaaact
     1081 tcctataaat tctgcaatca ccgtatcttc aatcaaaatt ctttcctcat ctatttcata
     1141 ttcaagacta aacggaaatt ctccatatgt aatctctggc aatggtggtg ctgtagttct
     1201 ccaaataaat acaataactg tgaatagaaa aaatccaacg atcgatataa atgttatgag
     1261 acctgctcga agtaaaaccc gatataataa aaatgctgta tttcgctttg ctatatctag
     1321 aaaaataaaa agtactgcaa tcataatgat agtaaaagtt gtaaaaaagc acattttttg
     1381 ccctcccttt ataaacatcg attctcaaat tctaaaccaa atcttgatag ttcaagttca
     1441 ggtataacgt ataccaacca tacatcccaa ttactattta tgaacttatg attatcactg
     1501 aataaatcac tccatcccct tgttaaaact tctacattaa ttacacctgg ttgttttcga
     1561 ctagctaatc caatgaactt atcaaccatc cttatccacc aaccacgaga atcttgacca
     1621 gaagtaagaa aaacagttct caaggttgat cgagcagttc cttccagttt ttaattaatc
     1681 tccagttata gataaatact tgatcctatc tatatcagga cttctatatt aagcaaaagt
     1741 ttatgtataa aactaaaatc ttcattcagt tgtctccccg ctttttatac gattgtatta
     1801 aaaaacaata gaagcctttc aacattatgt tactccagta aagttggaat tatagtttga
     1861 cggaagaaaa gcaagtatag cttttaaaaa aa
//
LOCUS       DAJSMK010000172         1876 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.183, whole genome shotgun sequence.
ACCESSION   DAJSMK010000172 DAJSMK010000000
VERSION     DAJSMK010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.183"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(320..775)
                     /gene="tnpA"
                     /locus_tag="ON488_002647"
     CDS             complement(320..775)
                     /gene="tnpA"
                     /locus_tag="ON488_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HCR3232769.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1018..1876
                     /locus_tag="ON488_002648"
                     /pseudo
     CDS             1018..1876
                     /locus_tag="ON488_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT          593 a          364 c          354 g          565 t
ORIGIN      
        1 atacttccaa aggtgttcga taatccagtg attttctagg aagattattt ctgcgccagc
       61 attttctaat gtttgaattt gtgttttgta atcttggttg cttgtgctaa ttcttgaata
      121 gccgtaaatt gccaaaattt catcaccctt tctggacata agtttctgac accagttaaa
      181 atcaagtcta tcagtaaccc atacacccgt gaggacgggt gtatttttaa tccccctaga
      241 aggggtcgac actcgctgcc ccttaaaagg ggatttttaa aagaccgcca actgctcatc
      301 ttcactcact tacttctctt tattttttaa atggttctac gtactctctt ttacttataa
      361 tatatcgaat gcgatcatca gcttcttgtt cacggatgta tttttcattt gtcttttgat
      421 tcaatccgac tgtactcaca tagtatctct tcgaccaaaa ggatttgttt ccgtatttat
      481 atttgagatt tgcgtgctgc tcgtggatta gtaccgcact acgacctttc agatacccca
      541 taaaactgga tatacatatt tttggtggta ctcgaacaag catgtgaata tgatctagca
      601 ttgcatgtgc ttctatgatt tccacatctt tcatttcgca caacttccta agtatttttc
      661 caagatcttt tcgtaattgc ccatagatta cttttcgttg atattttggt gtaaaaataa
      721 tatgatactt acaattccaa cgagtatatg ctaaactttt atcgtcattt gacatgaaaa
      781 aactcctttc gatctgatga gcggttggta gccactcact agtatatcga aaggagtttt
      841 tatcgctaaa gatacttctt ccacgcgtag aaacgcgcgg ttttcttgtt tcgcacgctt
      901 tacgcacaaa actgactgaa gtcattaaga aaataaaagg gtctaaaact tttaagtttt
      961 gtaccgaccc ccaaaagtta gaccaaaaaa tctaactttt ggaggtcggt attttttatg
     1021 gctaagtata cttttgaact taaattaaag atcgttcatg attacttgga tggtaaaggc
     1081 ggaagtgatt atctggcaaa gaaatattcc attaaggctc catcacaagt gaagcgctgg
     1141 atcaatgcct atcaagaatt tggtgaagag ggtctagtaa gaaagcgaca aaagaaaaaa
     1201 tattctgttc aatttaagct ggatgcgata gagttatatc taacaagtga gctgtcctat
     1261 cgtgaagttg ccaacacact taacatgaac aaccctaatt tgatcgctag ttggatgcgt
     1321 caattccgtg agggtgggat cgatggactc tcaaaaacga aaggatgtcc acctatcttg
     1381 tctaagaaaa atgaacccaa aaataagaaa aaatctacaa ctaaagcaac gtctaaagaa
     1441 cgtgaacgca tcgaggagtt ggagaaacga gtccgttccc ttcaaattga aaatgccttt
     1501 ttaaaagaat tgaggaagct gcgaaaacag gaagcccaac aacgacgaat gaagcaatcg
     1561 cacgaatcat cgcaagcctc cgaggaccgt ttaaattagt tgagcttcta gaaactttaa
     1621 agttccctaa ggcaatcttt atgtactggc aaaaacgatt ggaccgtaaa aatccagatc
     1681 aagagattga agcggaaatg cttaaagttc gggagaagca caaggattat ggctgtttac
     1741 ggatgaccaa tgaactaaga aaccgcggtt tctctatcaa taaaaagaaa gttcagcgcc
     1801 tgatcaagaa gctaggaata aaagtaacga catacacacg taaatcacgg cgctacaatt
     1861 cttatcgagg acaagt
//
LOCUS       DAJSMK010000173         1868 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.184, whole genome shotgun sequence.
ACCESSION   DAJSMK010000173 DAJSMK010000000
VERSION     DAJSMK010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1868
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.184"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            5..397
                     /locus_tag="ON488_002649"
     CDS             5..397
                     /locus_tag="ON488_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232770.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            398..1837
                     /locus_tag="ON488_002650"
                     /note="aph(2'')-Ia"
     CDS             398..1837
                     /locus_tag="ON488_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HCR3232771.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          778 a          137 c          320 g          633 t
ORIGIN      
        1 gtttatggaa gaagttttaa ttgatgataa tatggttttt gatattgata atttaaaagg
       61 atttcttaat gataccagtt catttgggtt tatagctaaa gaaaataata aaattatagg
      121 atttgcatat tgctatacac ttttaagacc tgatggaaaa acaatgtttt atttacactc
      181 aataggaatg ttacctaact atcaagacaa aggttatggt tcaaaattat tatcttttat
      241 taaggaatat tctaaagaga ttggttgttc tgaaatgttt ttaataactg ataaaggtaa
      301 tcctagagct tgccatgtat atgaaaaatt aggtggtaaa aatgattata aagatgaaat
      361 agtatatgta tatgattatg aaaaaggtga taaataaatg aatatagttg aaaatgaaat
      421 atgtataaga actttaatag atgatgattt tcctttgatg ttaaaatggt taactgatga
      481 aagagtatta gaattttatg gtggtagaga taaaaaatat acattagaat cattaaaaaa
      541 acattataca gagccttggg aagatgaagt ttttagagta attattgaat ataacaatgt
      601 tcctattgga tatggacaaa tatataaaat gtatgatgag ttatatactg attatcatta
      661 tccaaaaact gatgagatag tctatggtat ggatcaattt ataggagagc caaattattg
      721 gagtaaagga attggtacaa gatatattaa attgattttt gaatttttga aaaaagaaag
      781 aaatgctaat gcagttattt tagaccctca taaaaataat ccaagagcaa taagggcata
      841 ccaaaaatct ggttttagaa ttattgaaga tttgccagaa catgaattac acgagggcaa
      901 aaaagaagat tgttatttaa tggaatatag atatgatgat aatgccacaa atgttaaggc
      961 aatgaaatat ttaattgagc attactttga taatttcaaa gtagatagta ttgaaataat
     1021 cggtagtggt tatgatagtg tggcatattt agttaataat gaatacattt ttaaaacaaa
     1081 atttagtact aataagaaaa aaggttatgc aaaagaaaaa gcaatatata attttttaaa
     1141 tacaaattta gaaactaatg taaaaattcc taatattgaa tattcgtata ttagtgatga
     1201 attatctata ctaggttata aagaaattaa aggaactttt ttaacaccag aaatttattc
     1261 tactatgtca gaagaagaac aaaatttgtt aaaacgagat attgccagtt ttttaagaca
     1321 aatgcacggt ttagattata cagatattag tgaatgtact attgataata aacaaaatgt
     1381 attagaagag tatatattgt tgcgtgaaac tatttataat gatttaactg atatagaaaa
     1441 agattatata gaaagtttta tggaaagact aaatgcaaca acagtttttg agggtaaaaa
     1501 gtgtttatgc cataatgatt ttagttgtaa tcatctattg ttagatggca ataatagatt
     1561 aactggaata attgattttg gagattctgg aattatagat gaatattgtg attttatata
     1621 cttacttgaa gatagtgaag aagaaatagg aacaaatttt ggagaagata tattaagaat
     1681 gtatggaaat atagatattg agaaagcaaa agaatatcaa gatatagttg aagaatatta
     1741 tcctattgaa actattgttt atggaattaa aaatattaaa caggaattta tcgaaaatgg
     1801 tagaaaagaa atttataaaa ggacttataa agattgatta tataatatat gaaaagctat
     1861 tataaaag
//
LOCUS       DAJSMK010000174         1816 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.185, whole genome shotgun sequence.
ACCESSION   DAJSMK010000174 DAJSMK010000000
VERSION     DAJSMK010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1816
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.185"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            217..1257
                     /locus_tag="ON488_002651"
     CDS             217..1257
                     /locus_tag="ON488_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCR3232772.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
BASE COUNT          700 a          256 c          307 g          553 t
ORIGIN      
        1 gtgatatagt tactatgagc ttaaaccttg aaatagagcg gtttgcttta atttattttt
       61 taaggtaaac taaaaaaaga taaaaaaaga ctactgcttt aacaaagttt ggcgacttat
      121 cagcagtaga aaaatatata gtggatagat atatttgttt aattcattgt aacatagttt
      181 tgaacaaaac gctatcctac agaaagagga ttggctatga atgattttaa ttattacaaa
      241 tcaaaagaaa tttatcgtga aaaatattat caaatgccta aggtattttt tactaacgaa
      301 aaatacatgg atctatcaaa tgatgcaaaa attgcttata tgctacttaa agatcgattt
      361 gattattcag tcaaaaataa ctgggtagat tctgatgata atatattttt catattcaca
      421 gttgaagaat taatgaaatt gttacaatgc cgcgaaggta aagtatctaa aatcaaaaag
      481 gaattagaaa aagcaggtct tctgaaacag aagagaggaa gagtaaataa acgtgacggt
      541 aagattgaat ccatgcctaa tttattgtac ttaggcaagc cagaagtaac gaatcaagac
      601 gtctttaaaa tcatggaaga ggaagacaat actgatacca ccgtaattgc gaaaatcgca
      661 aatacggcaa aaccgcgaga aatcaatgat accaccgtaa ttgcgaaaat cgcaaatacg
      721 gcaaaatcca gtcatatcaa ggactcaacc gtaattgcga aaatcgcaga caatctattc
      781 tattctaatt ctatagacac taatagacac ataatagaca ctgaaactga tcagttacaa
      841 aatcaagttt tactagataa cttcgtcgac atcatgaaag aggacagtat aaatacattt
      901 gtaccagaaa atgtattaaa cttgataaaa acattttcta gtacttacga agacgctcaa
      961 aaaaccgtcc aaactattca taatgcaaag aaaaaagctg aagaattaga gcaaacagtt
     1021 gttgtttatg aagaactgga atcttatgga attgatgctg acaaaggatt atatatgact
     1081 ttgctgaaag cttatcaaaa acaaaaaact gaaaaagtaa acaatttgca gaatctaatt
     1141 ttcgtttatg taaaaaattg gtttgtcgaa aaagctattg cggcaaagct tgcaaacgaa
     1201 caaagagaaa catttaacga attaccaaca gttagtacgg aaaattggct agagtagttg
     1261 ataaaaagcg atcactataa aaatgatcaa ttttaaatta gaactttttt atgattttaa
     1321 ttttattaca aatgttacaa ataaatagct attattccgg agtttttaga ttaaaagttt
     1381 atgaaaacaa tcacaaacgt aggttttaaa gtcataatcg ttagatattt tagttatttt
     1441 tcattcaaaa aaatagggaa ctagtgtttg catatgtgct tttttgagtt ataataattc
     1501 atgaagagag gtaattcact tatttcccca agctgaaaag cctgatatta cttcttttca
     1561 ggcagtgctg ctaatattca attacacttt tttgtatatt tttagttgtt ttaaatttaa
     1621 ttgtctgata tgcttgtgat gaattgattt tcgttctgca cttttggacg ataaattgtg
     1681 ataattgaaa atacaaaaaa aagaaaggcc cctgtaaggc tcgggagact ggtaatctcc
     1741 gtcagtgtcc tacaggaaag cattaagatg acgccttaat gcgtgccctt cagtgttacg
     1801 gtattacccg caacgg
//
LOCUS       DAJSMK010000175         1762 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.186, whole genome shotgun sequence.
ACCESSION   DAJSMK010000175 DAJSMK010000000
VERSION     DAJSMK010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.186"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            200..622
                     /locus_tag="ON488_002652"
     CDS             200..622
                     /locus_tag="ON488_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232773.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLNRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            632..835
                     /locus_tag="ON488_002653"
     CDS             632..835
                     /locus_tag="ON488_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232774.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            1046..1630
                     /locus_tag="ON488_002654"
     CDS             1046..1630
                     /locus_tag="ON488_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232775.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          625 a          244 c          313 g          580 t
ORIGIN      
        1 ctaatcatac acgaggaagc catatgtcac ttttcttttt aaatggcaat attttttgta
       61 aataaatgtc aatcaagaaa atttaaacga ttatgacatt aaaaatatat tttatgaatt
      121 ttctagtata taacttgatt tatctgttaa gatttattaa gaaaacgttt tcttagtttt
      181 gatttcgagg tgatagacaa tgaaaaataa gtttatttta tctttaggta ttttaactat
      241 tggaattagt gtaactggaa ctacaattcc tacatttgct gatagtacaa atgaaccaac
      301 tactgtagta gataataacc aagaattaac tcctttaaat agggacggaa tagccattgg
      361 taacccaact aacgacttaa ctgttactga aaattattta atagtttctc cattacttgc
      421 tctagcagct tctaaaacga tacgagtgac aggaacgatg atttttgata aagttggttg
      481 gccttctaga cctcctcaat cacggaattg gaaagaaaaa agaaatggtt attggtacta
      541 tggaaaattg tatttacaaa gttataaatc agctggaaac aattggattg cgacttattc
      601 aggaacctta actagaaagt agggattttt tatgccagaa tttgtgaaca caccaaattt
      661 ttatcaagat agcgatattc taagtaaaat taatttaccg aaagaagaat cagctttaca
      721 agttcagcga actttacagg agacacaaaa aattcaaaaa tcaatttcta atctagaaga
      781 ttctgaagaa aaaagaaaaa aaagagacca aaaaacatat caaaaagaaa aataatgatt
      841 ttaaaaaaag agtgtctagt cgacattctt tttttctaat tgaaagtgtt cataaaatca
      901 cccatttctg gacactttct ttttttgctt tatttttcaa aaaaacaatt catttcatgt
      961 tcataaaccc ataacaatat ctatgttcag ttaaactata tggataaagt tatgttacaa
     1021 taaaattaat gaaggagtga tttttttgaa aataggatac gcccgggtat ctactggttt
     1081 acaaaatttg gatttacaag aagacagcct aaataaattt ggttgtgaaa aaatttttac
     1141 tgatcatatg agtggggcaa aaagtaatcg accaggatta gaaatggcca ttgattttgt
     1201 tcgctctggc gatacacttg tcgtttggcg cttagatcgt ttaggtagaa atatggaaga
     1261 tttgatttca atcgtcaatc gactgaatga gcgtggtgtg agttttcata gtattcaaga
     1321 aaatattacg atggacaaat caagttctac aggacagctc atgtttcatt tgtttgcggc
     1381 atttgcagaa tttgagcgta atttgatcct ggaacgatcc gcagcaggac gagcagctgc
     1441 tcgtgcaaga ggacggtttg gtggtcgtcc tgaaaaattg tctgaacaag atttggaatt
     1501 actgaagact ttagtggata gcggtacacc tattaagact attgcggaac ggtggaacgt
     1561 ctcaagaacc accatttatc gttatttggc aaaaatggag gagaaaaatg gaaagacaaa
     1621 ttctcattag tttttgtcat ttaatgctga aaatttttgc catttatcta gaaaagtgac
     1681 aatagtatga gaattttttg taagtgtcta ctgataactt attctcaaat gttgtaagga
     1741 ttttattcat ttgttaatat ta
//
LOCUS       DAJSMK010000176         1710 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.187, whole genome shotgun sequence.
ACCESSION   DAJSMK010000176 DAJSMK010000000
VERSION     DAJSMK010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1710
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.187"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..882)
                     /locus_tag="ON488_002655"
     CDS             complement(<1..882)
                     /locus_tag="ON488_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HCR3232776.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYK"
     gene            complement(1041..1307)
                     /locus_tag="ON488_002656"
     CDS             complement(1041..1307)
                     /locus_tag="ON488_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232777.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(1297..1653)
                     /locus_tag="ON488_002657"
     CDS             complement(1297..1653)
                     /locus_tag="ON488_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCR3232778.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT          493 a          328 c          207 g          682 t
ORIGIN      
        1 cttatagtcc tctgaaatca aaatatagcg tgatggatac tcatcaaaag aagaatcgta
       61 ttcttccttt aaaattcccg atttacttaa tttttctagt acatcaaata ctctatcact
      121 caagtaactc cttaaattgt tatcactttc ccattgaact acttttctat aagttgaatt
      181 atcagttgaa aagatagaat tttcatccat aaacgcatat attagcagca atctttcatc
      241 attgtcaaat tctattggat caaaaatatc taagttgtca tcaaaatctt tatcagttcc
      301 ggtaactttt ttgttaatta ctgaaggtgt cttgtaagaa atagaatcta aatcaaagcg
      361 ttttgattct aaattatttt gtgctttctc aattaaataa ttcacttttt ttgtgagaaa
      421 ccttctgata ttgtctttgc tatatgttcc ataaaaaccc ttatcttcta aagagtccct
      481 gtacttctta acttctatat actcttcagc caaaacttgt ggaactggtt catctaagaa
      541 aaaaacccct acctcgcctt tgctattttt ataaaagtaa tcaatttctg ctatagttcc
      601 cgatctataa ttatcaactg gagaacccaa cttatggcca aaaatcgcta ataatatatc
      661 actattttct acaatttgtt tattaataac actttgccca gagctattat ttatataagt
      721 aggaatcgca ttcgtttccc atcgaattgg catcaaaatt acttttgtat tatctgtatt
      781 ttctatattc catctatata tggtttcttc tacttcattc ctctttgctg ctatatcacc
      841 tggtgatgct ataaatactt ttattagatt tatggttttc atttattgta cctttctctt
      901 tatgtctctt taaagtaatt tttgtataaa atttattgac ttttacacta taggacaact
      961 tttatctatt tagtacaaaa aggcccacta aactaattga ttagttagga gcctattaca
     1021 ggtatatttt caactcgctt ttaagcaaat tctactacca gctttttgcc taatgcccta
     1081 gcgatatcat caagtttatc gaaagatacg ttatcccctc tctcaattcg agcaatagta
     1141 gattgagttg tatgtgcttt ttgtgcaagc tccgcttgag ttaggcctgc ttcctcccgt
     1201 gcatgataaa gagcaaccgc agtttcgagt tttcttcctt cacggtcata tgcttctgca
     1261 aaatctttgt ctttttgctt ttcttcaatc aattttttaa tcatcatttg tgaaccactc
     1321 ctctctaagt tcttttgcat gtttaagttc acttattggt gttttctccg tttttttagt
     1381 aaatccatgg gtaatgacat accttccatt gaccacatgg aaatagatag ctctttggat
     1441 gtttgatcct accttacttc ttaattcgta caaattagtg tctaattttt tcacccattt
     1501 caaccgttga gctactagca tcccattctt ttctgtttct tctattgtac gtaaaagctt
     1561 cgcactatct ttttttggta atgtttccaa ccattctaaa aattcatcat gaccattagg
     1621 tcttttaaat gtttcaaaag atattttttc catacccaat tatatcatat attgatttta
     1681 tattatagta tataacataa aaattcgaat
//
LOCUS       DAJSMK010000177         1700 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.188, whole genome shotgun sequence.
ACCESSION   DAJSMK010000177 DAJSMK010000000
VERSION     DAJSMK010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.188"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            103..1650
                     /locus_tag="ON488_002658"
     CDS             103..1650
                     /locus_tag="ON488_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HCR3232779.1"
                     /translation="METTDTLLQLLQEAHKTNQTQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKTDKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
BASE COUNT          573 a          308 c          349 g          470 t
ORIGIN      
        1 agctgggggg ttaacacaaa aaatgtgttg aacccctatt tcttgtgcgt ttcttgtggt
       61 attctgtaac aaaatcagtt cgattcaagg tggtgaaaaa ttttggaaac tacagatacg
      121 ttgcttcagt tgcttcaaga agcccataaa accaatcaaa cacaacaaca aaccattcag
      181 aatcttacaa ctgaaatcca actattgaat gaaaaggtca attatttaac caacaaatta
      241 tttggacgct ctaaagagac tctctttgaa gaaacgaatg ggcaattgaa tctttttagt
      301 gatgaagaaa tttctgtaag tgttccagaa gcagctgcca ccattattcc agtaaaagga
      361 catcaacgag ttgtaggaac gaaaacagac aaaatcaaac acttacctat aacagagaaa
      421 gaacatctcc ttcctttgga agaacaattt tgtgaacatt gcggttcaca gatgaaagat
      481 atcggacgga caaaagtacg agaagaaatt cgtttccatc aggctatgtt ggattgtctc
      541 acccattatc aacataccta ttgttgtaaa agctgcgaaa aagaaggact ttcttctttt
      601 aaaaaagcga tcgttcctaa acctttgatt tctaatagct taggttccaa tagtttagtg
      661 gcggaaacga tccggatgaa atttggtcag aaagttcctg cctatcggca agagaactat
      721 tggaaacaaa cacatgggtt ggatatttcg agagataata tcaccaattg gcatattaaa
      781 gcagtgcaaa acgcgttaga ccctttagga gaacgattaa gagtctatct taatcaagaa
      841 gagattctac acggggatga aacaagttat cgtgtgattg aaagtgccaa aacagatacc
      901 tattactggc agttttgtac aggaaaagac agtcagcatc ccatcgttta ttatcaccac
      961 gacgaaagtc gtgctggaga tgttccgaaa acttttctca aggagtttac agggtattta
     1021 cactgtgacg gctatagcgg gtataatgcc gtggaaagtg tacgacttgt ctattgtttc
     1081 gcgcatgttc ggcggaaatt tttcgaagca attccaaaag gaaagaaaaa cacggatatt
     1141 cccgcagctc aagcagtcaa acaattggat aaatggtttg tcctagaaaa gaaatggaaa
     1201 gacttttctc ctgagaagcg attaagctgt cggcaacaag aactgcgtcc attatttatt
     1261 gctttttatg agtggatggc aacgatagat cctgttgcaa aatccaagtt ggatgcagcc
     1321 gttcaatatg cgtgtaaact acgaagtggt tttgaaccta tttttgaaga tggtcgttta
     1381 gaactcacaa ataatcgtgc ggagcgaaat atcaaagagc tggtgatagg acggaaaaat
     1441 tggttgcatt ccacaagtct tgaaggagca cgaacttcag gaatcattct gagtgtatat
     1501 aaaacagcag aacttaacgg attgaatcct gtaaagtatc tagagtttct atttgataag
     1561 ataccaaatc ttcccgtact ttcagcagaa actttagatc aactgttgcc ttggaacaag
     1621 gatgtacaac aacatttttc tcgtaactaa aaacgccaaa cattcccgat tctattctat
     1681 aggtcgggtt atttgacgta
//
LOCUS       DAJSMK010000178         1700 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.189, whole genome shotgun sequence.
ACCESSION   DAJSMK010000178 DAJSMK010000000
VERSION     DAJSMK010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1700
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.189"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            142..1545
                     /locus_tag="ON488_002659"
     CDS             142..1545
                     /locus_tag="ON488_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HCR3232780.1"
                     /translation="MKKSLKLASAVLLMSHLLIATPFHVLASENSTYKIAKERTKTTE
                     MSNSDVTAEGSEFSTTSSSESSTTLNAESSTTSSSESSMTSNAESSTTSSSESSTISS
                     TESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFSTSQQIESTETFQSQPV
                     LSGNEEIHFDKNESVENFIMKIGDSARKIGQKYDLYASVMIAQAILESASGQSQLAQA
                     PNYNLFGIKGTYNGSFVIMVTNEDLGNGTLYKTQSKFRVYENYEESFEDYAKLLTKGI
                     SGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNGLIKTYDLTDYDKEVQGP
                     QMNKNGYQIPIHNYSISSLFGNRGDEFHRGLDMAAAQGEPIHAVKAGKVIKAEFHYSW
                     GNYVVIQHEDGSTALYAHQQQYLVKTGDNVVQGQMIGYVGSTGNSTGPHLHLEICKDS
                     SLSQSMLVDPKTLLFGN"
BASE COUNT          663 a          255 c          307 g          475 t
ORIGIN      
        1 gcagtaacag gattaaatag tggagcataa tcgttactaa atgaaatcaa gaaatatact
       61 gtattactca attcattgaa aatatttgtc atatttttta atagaaaaca ctattaaaga
      121 aaaaaaagag aggtaaatca aatgaaaaaa tctttaaaac ttgcatcagc agttctatta
      181 atgtcccatc tccttatagc aacacctttc catgtgttgg caagcgaaaa ttcaacatac
      241 aaaattgcaa aagaaagaac caagacgact gaaatgagta attccgatgt aacagcagag
      301 ggtagtgaat tttcaacaac ttcatcaagt gaaagtagta cgactttaaa tgctgagtct
      361 tcaacaactt catcaagtga aagtagtatg acttcaaatg ccgagtcttc aacaacttca
      421 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
      481 gaaataactt cttcgaaagt tacaaagcca aaccatatag agtcttcaaa aaaggaagcg
      541 ccaaaaacgg aaggacaaac aaaaactttt tcgacatcac agcaaataga atcaacagaa
      601 actttccaat cacaaccagt actatctggt aatgaagaaa ttcattttga caaaaatgag
      661 tctgtagaaa attttattat gaaaattggt gattctgcga gaaaaattgg tcagaaatat
      721 gatttatatg cttctgttat gattgcacaa gcaatcttag aatctgccag tggtcaaagc
      781 caattagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaagc
      841 tttgtcataa tggtaacaaa cgaagatttg ggtaatggaa cgctttataa gactcaatcg
      901 aaatttagag tgtatgaaaa ctatgaggaa agttttgaag attatgccaa attattaact
      961 aagggaatta gtggaaataa agatttttat gccggagcat taaaagctaa tagtaaaaca
     1021 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatactca atactattta
     1081 aagctaaatg gattaattaa aacctatgat ttaactgact atgacaaaga agttcaagga
     1141 ccacaaatga ataagaacgg atatcaaata cctattcata attattcaat atctagtttg
     1201 tttggaaatc gtggagatga gttccatcga ggacttgata tggcagctgc acaaggtgaa
     1261 ccgattcatg cagttaaagc tggtaaagtt attaaagcag agtttcacta ttcttgggga
     1321 aattacgttg ttatacaaca cgaagatgga tcaacagcgt tatatgctca ccaacaacaa
     1381 tacttagtaa aaactggaga caacgttgtg caaggacaaa tgattggcta tgtaggaagt
     1441 actgggaata gtacaggacc acacctccat ttggaaattt gcaaagatag tagtctttct
     1501 caaagcatgt tagttgatcc gaaaacctta ttatttggga actaaaaaga aaaagagcat
     1561 tttattagaa gtatggatta gggaatatag tagtagtggg ctctaaagat tatgaaatct
     1621 ttaagagctc tttttaagac gattgtttaa aacgaattaa ccaagtagga gctttcctag
     1681 aatttataaa attatagttt
//
LOCUS       DAJSMK010000179         1664 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.190, whole genome shotgun sequence.
ACCESSION   DAJSMK010000179 DAJSMK010000000
VERSION     DAJSMK010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1664
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.190"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            131..505
                     /locus_tag="ON488_002660"
     CDS             131..505
                     /locus_tag="ON488_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HCR3232781.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="ON488_002661"
     CDS             complement(619..1248)
                     /locus_tag="ON488_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HCR3232782.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="ON488_002662"
     tRNA            complement(1382..1454)
                     /locus_tag="ON488_002662"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          557 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt actt
//
LOCUS       DAJSMK010000180         1614 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.191, whole genome shotgun sequence.
ACCESSION   DAJSMK010000180 DAJSMK010000000
VERSION     DAJSMK010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.191"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            98..1564
                     /locus_tag="ON488_002663"
     CDS             98..1564
                     /locus_tag="ON488_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HCR3232783.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          450 a          292 c          334 g          538 t
ORIGIN      
        1 aaaattagtt tatatttctt aaataagttt tttagttaaa tttttcggta aagatgtata
       61 atattttctg aaaatttaaa gaattggggt atagattatg gaaaaacagc aagacaaggg
      121 cttcttcggg cagccgaagg gattgtcaac tttgttcttc actgagatgt gggaacgatt
      181 tagttattac ggtatgcgtg cattacttat ctattatatg tacgatacag ttgccaacgg
      241 gggacttgga ttaccacgag caacagcatt agctatcatg tcgatctacg gatctttgat
      301 ctacatgtct agtatcgtcg gcggatgggt atctgaccga gtgttaggag caaaacgcac
      361 tgtattcttc ggtggagttt tcattatgct tggccacatc gtcttggctt taccatttgg
      421 tgtaagtaca ttgtttgttt cgatggcatt gattattatc ggaaccgcct ttttgaaacc
      481 aaatgtttct ggcatggtcg gacatcttta ttcaaagact gacttgcgaa gagatgcagg
      541 attttcgatt ttttacatgg gtgtcaactt aggggcatta ttagcaccac taatcgttgg
      601 tacaatcggt caagaatata actatcattt agggttctct ttagctgcta ttgggatgtt
      661 ctttggatta ttacaataca tcatccaagg acgcaagaca ttagacggag tgggtacaac
      721 accgccgaat cctttgacaa ctgaagaacg taaaggattc atccgtaact tgatcatcgc
      781 acttgttgtt atcgctgcag tattcggcgg ggcacaacta actggtcatc tgacaattga
      841 cttttttgtc aatacaatca gtgtattggg gattatctta ccgttgtatt actttatcaa
      901 aatgctgact tcaaaagatg taactgctga agaaaaacca agagtatggg cttatatccc
      961 attattcctt gcagcaatca ttttctggtc attacaagaa caaggttcat ctatcttagc
     1021 tttatttgct agtgaacgta cacaatctac gctatttggt gtaacgatcc aagcaagctg
     1081 gtatcaatca ttgaatccaa ttttcatctt tattctgaca ccagtattcg taacgatgtg
     1141 gacgaaactt ggtgaacgtc aaccatctac agtagtgaaa ttctctcttg gacttttatt
     1201 tgcaggatta tcgtacttgc tattgatgtt gccgggtatg ctttatggta caagtggaaa
     1261 agtaagtcca ttgtggttgt tgggaagttt cttcatcgtg gttattgctg aattgtgtct
     1321 ttcaccagtt ggtttgtctg tgacaacaaa attagcacca cgagcatttg aatcacaaac
     1381 aatcgctatt tggttcttag ctgatgcttc ttcacaagca atcaatgcac aaattgcacg
     1441 cttctacaca ccgggaacag aatctgctta cttcggtatt atcggtgcag tagcaatcgt
     1501 cggtggtatc ttgctattta ctgtgaaaga accaatcaaa aaactaatgg gctctattca
     1561 ttaatcaatg aacataaaaa caggaattgc ttatttgcag cagttcctgt tttt
//
LOCUS       DAJSMK010000181         1571 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.192, whole genome shotgun sequence.
ACCESSION   DAJSMK010000181 DAJSMK010000000
VERSION     DAJSMK010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.192"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            273..1442
                     /locus_tag="ON488_002664"
     CDS             273..1442
                     /locus_tag="ON488_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HCR3232784.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
BASE COUNT          576 a          220 c          256 g          519 t
ORIGIN      
        1 gttggtagta taatttaaag gtaataagtt attcttttat tactatgttt gggttttata
       61 gcaaagaaag tttaataaga gtttggacct agcaaacaat attaatgagg tcattaaatc
      121 ttattatctt tagtgatata acgaaatatc tacacagaca aaatgatagc gtaaaatatt
      181 ttgtgtaaat agatatttag ggtagaaaaa aagaaagtcc attctgtaaa attaaagtta
      241 ccacaaccga aattttatag gaggactttc tcatgcccaa ttttactaca gaaattatgg
      301 aaacactaat caataaaggt gatttagatg aattatttcg atgtcattta gaattagctg
      361 ttaattcatt attgcaggct gaattaacag cttttcttga ttatgaaaaa tatgatcgtg
      421 ctgggttcaa ttcaggtaat tcccgtaatg ggaattattc acgttcattc agaacagagt
      481 atggagaatt aaatttggta attcctagag atagaaatgg taagttttct caacaaactt
      541 tacctgctta taaaagaacc aatgactctt tagaaaccac tattattcag ctatttcaaa
      601 aaggaattac tatgtctgaa atctctgaat tgattgaaaa aatgtacggg catcactata
      661 cgccacaaac catttcaaat atgactaaaa tagtttctga agatattatt gcctttaaag
      721 aaaggtcctt agaatccaga tactctgtca tttttatgga tgctactcac attcctttaa
      781 aaagacaaac tgtttcaaaa gaagcagttt atattgtaat tggcattcga ttagatggaa
      841 ccaaagaggt tcttgggttt agtcttgctc caactgaatc tgcttatgtt tggaaagaga
      901 ttcttcaaga cctaaaagac cgtggtttaa aagaggtttt attagtcgta actgatggtt
      961 taagtggcat taacgatagt attcatagtg tttatccaaa tgctcaattt caacaatgtt
     1021 gtgtccatat atctagaaat atcgctcata aggttcgtgt tagtgatcga caagaaatct
     1081 gtagcgattt caaattagtt tatcaagcaa gttcaaaaga agaagcaaat aatcaaataa
     1141 ggtttatgat agataaatgg aaaaagcagt atccacgagt ggttaaattg ctcatgaatc
     1201 ctgctatatt aaccttttat aatttccctc cgtcaatcag aagaactatt tattcaacta
     1261 atttgattga aggttttaac aaacaattaa agaaatatac caaaagaaaa gagcaatttc
     1321 ctaatgaaga atctctggag agatttctag tatctcaatt caacaactat aatcaaaagt
     1381 ttctatgccg agttcataaa ggttttaaag aaatacatga tacattagaa tcaatgtttt
     1441 aacttgatca acagaatggg cttttccatt tacacaaaat tattgacgct cccgacaaaa
     1501 ttatgatctt gcgtaaagtt ataaaatatt aataaaaata ttttattaat gaaaagcttg
     1561 gtagcacggt t
//
LOCUS       DAJSMK010000182         1522 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.193, whole genome shotgun sequence.
ACCESSION   DAJSMK010000182 DAJSMK010000000
VERSION     DAJSMK010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1522
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.193"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(189..761)
                     /locus_tag="ON488_002665"
     CDS             complement(189..761)
                     /locus_tag="ON488_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232785.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(777..1382)
                     /locus_tag="ON488_002666"
     CDS             complement(777..1382)
                     /locus_tag="ON488_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HCR3232786.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          426 a          329 c          217 g          550 t
ORIGIN      
        1 atgatggtat cctaatatag taagcgtggc tagcatacct ttaattactt taccttttac
       61 agttaccata cacatttttt gagcagaaat caagtaaata aaaaaatatt atatttcaca
      121 acatgctaat agactcatat ctagaacgca ttaagtattt acctgtctgg ttcgctgaga
      181 cttctttttt aactttcttc aattttcttc tttattctaa aaagcgtact gcgactgaaa
      241 ccggttatag cttcaacttc cttatacgat ttacctgaag taagcagttc atatgcgtgc
      301 ctcttcttcg gtgtgattgt tgctttcgga cgtccttctc tgaaattagg attattcttt
      361 cttgcaaaca tttttccttc ttgggtacgt tccacaatca tatcacgttc catttctgct
      421 acactcaaca acgtccgtgt caccattcgc cccatggacg tattttcaat cgttcctaga
      481 ttcaaaacct tgatcgttac gttatcatcg agtaaaggtt caatgatctc taatgcttct
      541 ctcgtgttac gagcaaatcg atcaagcttc gtaacaacta tttcatctcc aggcttcaga
      601 ccagccaaca gctgattgaa ttttggccga tcccgttttg tacccgtaaa tttttctgaa
      661 aaaatattct tcttctctac gccgttctca agcaactgtt gaatttgttc ttttgtactt
      721 tgagaagcgg ttgagacacg tgcatatcca tatttcgtca tttggtccac ctacttttac
      781 aaatcatcta tcgtatactc agaataccct tcatagaaat agctgacatc gattcctttc
      841 atatataact cgcgatcgtc aattttatca gtcagagcat tggaaattag atagcgtatt
      901 tccaaatcgt ttatgggact tcgctccatt gcagaaagat agtctgcttt atcgattaag
      961 ttccaatcta caactttttg caattcttcc tttaaaatga gatccagcca aattctagta
     1021 cttcggccat ttccttctcg aaatgggtga gcgatattca tctccacata tttcttgata
     1081 atctcttcaa aagaagtttg tggcatctga tcaatatgct gtaacgaatg ttctaaatac
     1141 ataactggtg caaatcgaaa atttcctttt gcaatattga ccgatcggat ttttccggca
     1201 aaatcgtaaa tatccgaaaa tagaaattca tgaatttcag ataaaccttt aaatgtacca
     1261 acttcgattt catttatttt tccacaatcg tacaattctt tcgctttttg tttactgagt
     1321 ttttcttcaa ccttagccaa ctcaacttga ttggttaatc ccaatttatt ctctaaaatc
     1381 atgcgaaatc tccttaactt tatgacataa gtttatgaaa cactctcaac cccattatat
     1441 cgcgattttg tttatgtgtc aaaaactatt aagtttctga cccccgatag atttttcaag
     1501 tgtctctatt ttgcacagtc ta
//
LOCUS       DAJSMK010000183         1482 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.194, whole genome shotgun sequence.
ACCESSION   DAJSMK010000183 DAJSMK010000000
VERSION     DAJSMK010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1482
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.194"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            70..153
                     /locus_tag="ON488_002667"
     CDS             70..153
                     /locus_tag="ON488_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HCR3232787.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            278..1015
                     /gene="erm(B)"
                     /locus_tag="ON488_002668"
     CDS             278..1015
                     /gene="erm(B)"
                     /locus_tag="ON488_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCR3232788.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1185..1445
                     /locus_tag="ON488_002669"
                     /pseudo
     CDS             1185..1445
                     /locus_tag="ON488_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
BASE COUNT          563 a          235 c          251 g          433 t
ORIGIN      
        1 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
       61 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      121 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      181 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
      241 atttatttac agatgtaata acttcaggag tgattacatg aacaaaaata taaaatattc
      301 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      361 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      421 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      481 agaaaaatta aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca
      541 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      601 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      661 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
      721 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
      781 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
      841 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      901 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      961 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1021 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1081 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1141 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1201 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1261 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1321 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1381 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1441 aataaacatg gggctgaccc aaaagtagct cctatatgaa aa
//
LOCUS       DAJSMK010000184         1465 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.195, whole genome shotgun sequence.
ACCESSION   DAJSMK010000184 DAJSMK010000000
VERSION     DAJSMK010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1465
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.195"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(37..1068)
                     /locus_tag="ON488_002670"
     CDS             complement(37..1068)
                     /locus_tag="ON488_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HCR3232789.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT          444 a          236 c          251 g          534 t
ORIGIN      
        1 catagtttat tgtgaaaaaa agatcataca tttgttttat atggaagaaa cccgaacgaa
       61 tgccgctaat tcgtgataag aaaaatcaac catcttttcc cagatatctt gaaaagaatg
      121 ggatgagagg tatcgattac cacataaata atttaccgcg tcagcatcat ctaaatatag
      181 ttctgcataa taacgatatg tttttctgca tagttctggc gatacgtttt tatatactgt
      241 aattttgctc aaaatttggc gaatagtccg aggagaaatt tgctgatcat gtgaggaacg
      301 aaaaacaaaa gaattttcgt ccgtattttg tgctgttaac ttaaaatagt tctccagaaa
      361 tggcatcgct tcttttggta ttggtacttt attcagtctg ttttcttttc tattcagatt
      421 aagaatctgc ttggtcaaag atacatcttt acgtttaagt tctactactt catggatctt
      481 taatccgcaa tacagaagaa tggcagtaat tgcaaggttc ctcggtctat tcttttcttc
      541 aaagctagct tctctgcttg tttgaaagcc ttcaatcggg ataaacaaat gctcaaaatc
      601 tttgaaaagt tctgcatcga tatatcgcgg agctgctttg gttgtttccg gtaaacttgt
      661 acccaaaaga gaaatctctt cttcaatcag tcctttttga tacaaaaatc gtaaaaaatg
      721 atttaatgaa tattgcttcc ttgaaatccc gtaatagcta ttttcaaaca attgctccgt
      781 ttcttggttc gctgtagttt ggaacgaacg agtatgtcga tagattttag ctaagaaatt
      841 ctgataatct tgtttttcta aatggataat cagctgatca tccacttctt cagaaaatac
      901 ttttctcaaa taatcagtaa acagatgaaa atcttttgcg tattcatagc gactgcctaa
      961 tgaaagggaa gaacgatttt cttctaaaaa ctgttgaaag acggaaggga gcaagtgtgt
     1021 acgttgcttt aacttttctt gcagttgttt tctagttttg ctgtccatta caaattccct
     1081 ccaatagtgt tcattttcta tattttaccg catttcatca aatgaagata gacagtttgt
     1141 cttgatctta ggaagcaaat ttttaactaa gtactagcta aaagatatga agtaagaaga
     1201 tacattttta gttattttat tagtgcagtc attcttttga tcttttaatt gatttatcct
     1261 ctttttagct atgtggttac ttcatgagca atgaaatgga tttggttcgt tctaatggca
     1321 ggaggctctt tcttttattt ccgaaaaatt agaaaacatt ttttcagaat cgattggctc
     1381 tccatttatt caataatggt ttgtctaacg atattgttgg gataattctt aaagaagtat
     1441 tagaaatagt tggtacttca ttact
//
LOCUS       DAJSMK010000185         1457 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.196, whole genome shotgun sequence.
ACCESSION   DAJSMK010000185 DAJSMK010000000
VERSION     DAJSMK010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.196"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(943..1356)
                     /locus_tag="ON488_002671"
     CDS             complement(943..1356)
                     /locus_tag="ON488_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HCR3232790.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
BASE COUNT          534 a          238 c          216 g          469 t
ORIGIN      
        1 tttgttacta tgaataacat aataagaaag taaagtggat tgatttgaga tctttttata
       61 cttcaaaaaa gataacaccc aactttcaaa aatatgtttt ggaagttggg acaaacgagt
      121 taatacattt taatacatta ttttttattc aaaaaaaata gcacaatggc aaagatcgta
      181 agagagatca taagccccaa tgaatgacta aaaagaaaag cagaatcaca tgccatatca
      241 tcccatattt cttcaagaaa ataaataagc gggaaaaagg gaaggaatag tagaacatcg
      301 atccagcacc atttttttct tcttttgaaa taacataaaa caataaacat gaacgtgcag
      361 ggaagtaaaa acaaagcttt actcataact aacaaaatac cagctccttt tatttttttc
      421 tcccccacat tcaaagagta acaatggtat gtacttaata atagaaaaat ggatcaactt
      481 gtatgaataa cagctgaaaa gatctgcacc aaataaaaaa cttccagcca aaactgactg
      541 gaagtttatt tttttctgaa atattctaac acaaatatga aaaagatggc cgaagctaat
      601 aagccgattt cgtagcaaaa caatgagata ccagagtcgt aataataaaa tcctctaatc
      661 ttatggataa aatagatcat cggacaagca gataagagta agtatttgtt aggccttttg
      721 aataagtaaa agaaagcact ggtcattatg ataaatggta tccaaaacaa aagtttactt
      781 aagacaatca aatgatcaac tcccatattt tttaccaaga gagatcataa catctttatc
      841 gtaaaaacaa aatatttttt tgctcatttt gaaaatttaa acatactcgt tcttatccaa
      901 atatataaaa atcgcccctc attcatcgag aggcgataag ttctaattta actcaatttt
      961 ttttgtttct tttggctgat aagctgtttt aggtaatacc aatttcagca caccgttttt
     1021 aaaggttcca gtgatttttt cttcatcaac attaggaaga tagaatgaac gtttgtaaga
     1081 gaccgaatgt ctttctttcc gtacatagtt gccatcttct ttatcttctg tatgggactc
     1141 atgattggcg gagatcgtca aagtattatc tgaatattca actgtcgtgt cttctttgtc
     1201 acagccaggc atatcagcag ttagtttgta ttctttttca ttttcgacta aatctacttt
     1261 tggataactt gaaacaccta aaaaatcatt gaatgctgga ctaaacacgt cattgaaatc
     1321 agggaacatg tcgcgaatgc taggtacatt tgccattttt gatcatcctt tcaataagta
     1381 ttttttattt atccctattt acgtaataac tctattttga aaaaaatgca agtataatgg
     1441 ttagctttgt gaatatt
//
LOCUS       DAJSMK010000186         1456 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.197, whole genome shotgun sequence.
ACCESSION   DAJSMK010000186 DAJSMK010000000
VERSION     DAJSMK010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.197"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            108..1040
                     /locus_tag="ON488_002672"
     CDS             108..1040
                     /locus_tag="ON488_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HCR3232791.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="ON488_002673"
     CDS             1112..>1456
                     /locus_tag="ON488_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232792.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DAJSMK010000187         1424 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.198, whole genome shotgun sequence.
ACCESSION   DAJSMK010000187 DAJSMK010000000
VERSION     DAJSMK010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.198"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(150..1337)
                     /locus_tag="ON488_002674"
     CDS             complement(150..1337)
                     /locus_tag="ON488_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HCR3232793.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAJSMK010000188         1423 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.199, whole genome shotgun sequence.
ACCESSION   DAJSMK010000188 DAJSMK010000000
VERSION     DAJSMK010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.199"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(79..405)
                     /locus_tag="ON488_002675"
     CDS             complement(79..405)
                     /locus_tag="ON488_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232794.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(392..1195)
                     /locus_tag="ON488_002676"
     CDS             complement(392..1195)
                     /locus_tag="ON488_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HCR3232795.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
BASE COUNT          418 a          239 c          197 g          569 t
ORIGIN      
        1 cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat attatgatat
       61 cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat atccttcaat
      121 caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg gtttactttt
      181 gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg gatttatacg
      241 aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac ttatattttt
      301 cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat ttttatttcc
      361 tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa tcaccaactt
      421 cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag ggtttattaa
      481 aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc ctacgaatat
      541 aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca gacgtcattt
      601 ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt acttcaagct
      661 tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt agtcctttta
      721 atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta aatgcgttga
      781 ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag ttgtccttga
      841 ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat tccctctctg
      901 cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc agaatagcat
      961 ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt gttccatcta
     1021 tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact aaaagtacat
     1081 ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta gttttagaaa
     1141 ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc cccattcatc
     1201 ttatattata atataattat atcataatat tgtgatattg caatatcgta tatgcattat
     1261 attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga tataaagatt
     1321 attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat tttttattaa
     1381 tgataagaaa tatgttttgc gagcagcaac tagaataatt taa
//
LOCUS       DAJSMK010000189         1421 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.200, whole genome shotgun sequence.
ACCESSION   DAJSMK010000189 DAJSMK010000000
VERSION     DAJSMK010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.200"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            96..1388
                     /locus_tag="ON488_002677"
     CDS             96..1388
                     /locus_tag="ON488_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HCR3232796.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          462 a          291 c          257 g          411 t
ORIGIN      
        1 accagcatct tttttatttt ccaaaacata tagaaaagac accttgaaat cctttagaat
       61 taatttggcg aaccaaccca aaaggaggaa tcaagatgtc ttacactcac cttatcaaag
      121 aaacattaga tattctagac ttatcagtta cttttaacga aaattgtctc acaaaagaaa
      181 aatacaaagg gcaaatctgt catatttatc gtggaaactt gatttataca gcccaagaat
      241 gcatccactg taaacaccag attgcttcag atattgtgcg ttggggtaca acaaccgtcc
      301 ggttgttaat gaacgatgtt tctgaatacc gtacctacct cgaattgaaa aagcaacgct
      361 tcaaatgcaa agcttgtcag cggacctttg tcgcagatac ttctgttgcg aaaaaacatt
      421 gtttcatcag tgagaaagtc cgctggtctg tcgtgactcg tctgaaaaaa aatacctcaa
      481 tgacagagat cgccgctcag aaaaatctat cggtctcttc tgtttaccgt attatgaagc
      541 gattttatcg tccgttgaat ccttttcgga caccgttacc taaggtactt tgttttgatg
      601 aattcaaatc agttcggggt gtttcaggtg ctatgagttt catcatgatg gatggacaaa
      661 cacagcgctt attggacatt gtcgagaacc gacaactgcc ttttttaaaa cgttatttta
      721 gtcatttttc acgagaaatt cgtgaagcgg tcgaatggat cgtgattgat atgtacgctc
      781 cttatgtatc gctcgttaaa aagctgtttc caaaagcaca gctgattatt gaccggtttc
      841 acatcgtcca acatattggt cgtacctttc gcaatcatcg aatcaaagaa acgaaccaac
      901 tattaaaaag caaagaacaa aaacactatc aattaggtaa gcaattaaaa agatactgga
      961 aacttcttca aaaagatgaa cgcaagcttg attatactcg acgcctttgg cgacctggct
     1021 tcaaagctca tttaacagag accgatattg tggatcgctt actgaaaggg agccctgctt
     1081 tgcgtgtagg ctatcagtta tatcaagact ttctttacgc tgtaaaggaa cgagactacg
     1141 tatcgtttga agaactactt accaataata tcatgcttcc cgaaggctat cagacgacct
     1201 tgagaacgtt ccagaaattt ctgccacaaa tcaaaaatgc tttacaacaa agttattcaa
     1261 atggcccact tgaatgtctg aacaaccata tcaaagtgtt aaaacgaaat gcatatggct
     1321 ttcgtagctt ttataatttc aaattgcgca tcatgattcg tcatggcaac gcattgattt
     1381 tcaactaaaa aagatcaaga ggaactgatc cacttgatct c
//
LOCUS       DAJSMK010000190         1387 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.201, whole genome shotgun sequence.
ACCESSION   DAJSMK010000190 DAJSMK010000000
VERSION     DAJSMK010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.201"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            281..1321
                     /locus_tag="ON488_002678"
     CDS             281..1321
                     /locus_tag="ON488_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HCR3232797.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          547 a          189 c          219 g          432 t
ORIGIN      
        1 attttttgtt ttgacactgg tagtacttaa ttatctttaa ttttaaaact aaattttatt
       61 catacgtttt tctggtagta tttaattata aataatattt atttaaagta gttcttaatg
      121 actttaaagg tagtacataa ttcattttat ttctgatttt aggtagtatt taattaaaaa
      181 acagttttaa tgcgtttgca ttttttattt atctttgcta ttttcgaaaa gagtaggtaa
      241 ttttacataa ataaaacaac gtgaaagtag aggatctaca atgactgatt ttaaattttt
      301 taaggcggat agagtttaca acgaattatt ttatcaattt ccaaaagtct ttattgtttc
      361 tgacgaatac aaaaaaatga aagattcaac taagattgcc tatatgcttt taaaagcaag
      421 attagagatc gcaatcagca aacggcaaat cgatgaagaa ggtaatgttt attttactta
      481 tacgacaaat gaactatgta gagtattaaa ctgccaaaaa caaaaagcga tagcaatcaa
      541 aaaagagttg gaatcctttg gtttattatt acaaaagcag atgggattta acaaacagtt
      601 agggaaaaat aatcctaata gactatatct agcagaatta aaagtctcag aaaatgatat
      661 ctacttactc gaaaaatttg atagagagaa tagggaaaac gttgataaat cagagggtat
      721 gaaaatcata cccaccctcg acgaaaaatc agacgctgaa tcccttgggg ctcaagaggg
      781 tatgaaaatc ataccgtgcc aaaacgttga taaatcagag ggtatgaaaa tcataccaga
      841 acttaataat aatatattag acactaatag acacaatata gacactgaaa aagaccgcct
      901 acaagatcaa ttgttgttag acaattttga gacaattatg acaaacgaca gcattgctac
      961 gtttgtccct gaacgagtat taaatttgat aaaaacattt tcttcaagtt acagtgaagc
     1021 tcaaaaaacc gtccagacta ttcataatgc aaagaaaaaa gctgaaatag aaagtgatat
     1081 ttcgatagtt tttgaagaac tcgatagtta ttatgtcaat gcagaacaag aattatacac
     1141 gacactgtta aaagcctatc aaaaattaaa aaccgaaaaa gtcgaaaata tccagaacct
     1201 gatttttgtc tatgtaaaaa attggtttat cgaaaaacca atagctgcta aagtatcaag
     1261 tgaaaaacgt ttgaattatg caagctcccc aagcactatt acgaaagact ggttagagtg
     1321 aaactttact gacaaagtga ttgttgcttc atggagtaac attaaaatta aaaatttttt
     1381 attattc
//
LOCUS       DAJSMK010000191         1372 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.202, whole genome shotgun sequence.
ACCESSION   DAJSMK010000191 DAJSMK010000000
VERSION     DAJSMK010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.202"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="ON488_002679"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="ON488_002679"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HCR3232798.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          477 a          181 c          229 g          485 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa tt
//
LOCUS       DAJSMK010000192         1364 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.203, whole genome shotgun sequence.
ACCESSION   DAJSMK010000192 DAJSMK010000000
VERSION     DAJSMK010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.203"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(140..1288)
                     /locus_tag="ON488_002680"
     CDS             complement(140..1288)
                     /locus_tag="ON488_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3232799.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          392 a          242 c          217 g          513 t
ORIGIN      
        1 taaacctgac ggttcttaac gcttgaagtg ggagcttctt gggaatagag catacttgat
       61 agcgtatttc tttactaaca gcggtgtctc ttatttacca agctatcccc gtagttccta
      121 cggttcttga tgattggatc taagccaatc ccatagaatg tagtcttaga ccttcggtca
      181 gaatattgat actagcattg atatcacgat catgatgagt atgacaaaca ggacaagtcc
      241 attctcgaat ttcaagagat ttcttgccat ctttatgtcc gcactctgaa caaatctgac
      301 tagacggaaa ccatttatct actttgatga tttttcgtcc ataccagtca gccttgtatt
      361 gtaatttagt cacaaacttt gaccaagaaa catcagaaat acttttagct aatttatgat
      421 ttcgcaacat accttttgtg tttaagtctt caatacagat aatatcgtga tttttgatca
      481 tttctgtact caacttattc agaaaatcag tacgttgatt cattactttt tcatgcaatc
      541 tagctacttt gcgtttttgt ttttgataat ttttagcttc aaatagattg gtacctttat
      601 ttttagccaa taaagcacgc ctagacaatt tgcgttgttc acgctttagt ttcttttcca
      661 ttttggacgt gaatttatta ttatcaattt tttgtccatc agaaagaatc gcaaagtcca
      721 taatacctaa gtcaatacca attgtggaat tagttttagg taattcgata atttcttctt
      781 tacacaacaa agaaatatag tatttaccgc tagaatgacg tgatattgta gcggatttga
      841 taatcccttt tggttgtcta tgaagcttaa ttcttactaa tgacttcaat ttaggaactt
      901 tgatgaattt actatcaatc aaagcaactg taccattttg attattcgtt gtataactct
      961 gaacaggatt tttcttactt ttgaaacgtg gaaatccaac ggatttatcc cgaaaaaaat
     1021 tcttgtatgc tttatctaaa ttaagttggg cattggctaa agcaaggcta tcaatttctt
     1081 tcaaaaacgg aaattctttc ttgtatttag ctggtgtcgg aaaagtcatt tttttagaag
     1141 aatcattttt aacttcttca tacgcctttt ttcggtcatc aagcattaga ttgtagacct
     1201 tacggacaca accaaaagat ttggcaaaga agatttcttg ttcctctgtt ggatagattc
     1261 tgaatttgta tgcttttagt tgttccataa agttcaccta ctttctattt atgattgttt
     1321 ccttgatttt ggatatactt cttaatcaca tcaattggtg cgcc
//
LOCUS       DAJSMK010000193         1342 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.204, whole genome shotgun sequence.
ACCESSION   DAJSMK010000193 DAJSMK010000000
VERSION     DAJSMK010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1342)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1342)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1342
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.204"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            297..704
                     /gene="arsC"
                     /locus_tag="ON488_002681"
     CDS             297..704
                     /gene="arsC"
                     /locus_tag="ON488_002681"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HCR3232800.1"
                     /translation="MRKIYFLCTGNSCRSQIAEGYGKAILPTDEFEIKSAGIEQHGLN
                     PRAVQVMAEEGIDISTQTSDLIDMDYFNQADLIITLCGDAKDKCPVIPKGIKHVHWDL
                     EDPAKATGTEEEIINKFREIRDDIKSRVANLLD"
BASE COUNT          476 a          197 c          251 g          418 t
ORIGIN      
        1 tcaaatttta atttgaatat gtgaggagtt atatagattg tatggatgca tctatataag
       61 tagtgatttt caaattagat tgaatcgaat gcaaataata aactaattaa tttgaactga
      121 aagacagaag catttgacaa aacatagatg attatctata tttttacata agcgccggca
      181 gttggcatct tagttgaagt gccagtcatg ttactgttag ttaaaatatc taatcgcaca
      241 aaaaaattgg ttcattcaaa atccatcaga attgtctgat atcggaggaa ataataatga
      301 gaaaaattta ctttttatgt acaggcaatt cttgtcgtag tcaaattgca gaaggctatg
      361 ggaaagcgat tttgccaaca gatgaatttg aaattaaaag cgccggcatt gaacaacatg
      421 ggttaaatcc tagagccgtt caagtaatgg ctgaggaagg gatagatatc tctacgcaaa
      481 catctgattt gatcgatatg gattatttta atcaagcaga cctaattatt acgctatgtg
      541 gcgatgccaa agataaatgt ccagtaattc caaaagggat taagcatgtt cattgggatt
      601 tggaagatcc agccaaagca actggaacag aagaagaaat cattaataaa ttcagagaaa
      661 ttagagatga tataaaaagt cgtgtagcga atttgctaga ttaagtagca actgtcatct
      721 atctcggtaa aagataaaaa gacgtaaaat gtccttttga taaattggaa aattaaagta
      781 aaagccgtgc gaagtgaaac ataaatcttc gatggctctt actattttaa gagaaaagga
      841 tctgcttttg gcgtaaaatt ggatttatct atctgacata ctgacgagta ttttttgacc
      901 ctatatttga ccttctcaat cacatttaag taggtgtgac cggcttatac aattattcga
      961 gaatctagta gcttagctaa ttctggcctt gaaaccccta ttagacagct atccagccat
     1021 caatacggtc tcaaataaat aagaggggag gaataactct aaaaaagatt gataaactag
     1081 taagaaaatt gtattcaact accattcatc tttggttcaa attggttcaa gtaatatcaa
     1141 tattaatcct attttatcca tatcaaactg ttttttagat gtttgtaatg ttgatataat
     1201 tggatttcta ttgatagaag tacttgtaat aagtacgagt cacatctcaa aacgttaatt
     1261 gcgattatcg ttcgagttca cgagttacga gaatcgtact gggcgaagca atgctgagcg
     1321 cagttacctt aatcctaact tt
//
LOCUS       DAJSMK010000194         1337 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.205, whole genome shotgun sequence.
ACCESSION   DAJSMK010000194 DAJSMK010000000
VERSION     DAJSMK010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.205"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..1337
                     /locus_tag="ON488_002682"
     rRNA            <1..1337
                     /locus_tag="ON488_002682"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          358 a          293 c          406 g          280 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggactta
//
LOCUS       DAJSMK010000195         1295 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.206, whole genome shotgun sequence.
ACCESSION   DAJSMK010000195 DAJSMK010000000
VERSION     DAJSMK010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1295
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.206"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            11..>1295
                     /locus_tag="ON488_002683"
     CDS             11..>1295
                     /locus_tag="ON488_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HCR3232801.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLI"
BASE COUNT          435 a          252 c          248 g          360 t
ORIGIN      
        1 gatacgctat atgaatgatt ctatcaaaaa aatgctgaga ataacagaga aagatttgat
       61 gattacagag gtctcttacg agacccttca gaagaaaaag acgttggtcg tcgatgctgt
      121 tctctcgcct actcctcgtg cttgtagaag ttgtggttct actgtggtag atggaaacgg
      181 gaaagcaatt atagtgaaaa atggaaaaaa ggaaacgatt gtccgttttg aacaatacaa
      241 tcatatgcct ttggttatgc gcctaaaaaa gcaacgctat acctgtaaaa actgtcgcac
      301 ccattggacg gctcaaagtt attttgtcca acccagacat tcaatcgcaa atcatgttag
      361 atataaaatt gcttctttac tgactgaaaa agtatcttta tcttttattg cgaaaagctg
      421 tcaggtatct ttgaccaccg ttattcgtac attgaaagag tttaaaagct atttaccaaa
      481 gcaatctaag aagatcctcc ccagagtatt gatggttgac gaatttcgtt cgcatgcttc
      541 catagaagat aagatgagct ttatttgcgc ggatggcgaa acaggaaaat taatagatgt
      601 tttgcctacg cgtaaattac ctcgattaac aagctatttc ttaggttgta ccaatccaga
      661 agaagtagaa ttcttggtga cagacatgaa cgccgcctac ttccagctca ccaaacgtgt
      721 tctgccaaat gcgaaagtcg tgattgatcg gtttcatatt gtcaaacaca tgaatcaagc
      781 gttcaatgag ttgcgtatcc gtgaaatgaa tgaacttcgt aaagccggac agaaaagcca
      841 ggcagaaaaa ctgaaaaaga actggcgctt tttgctaaaa aatcgtgcaa acatcaacca
      901 ttatgaatac aaaacatgga aaagtttccg agcaccaaaa tacccatttc ttactgaagc
      961 aatgatgatt gatcgattgc ttgagttttc tccgccccta aaggaggcgt atcccttttt
     1021 tcatgaatta gttgaagcct ttcgagacaa agaccctgac ttatttttct ccttattggc
     1081 agaacttccc gaaacgttag atgacagctt tcgggaaaag cttcaaaacc ttctgaccta
     1141 tgaagaaggc atcaccaacg caatgatcta tccttattcc aatggaaaaa tagaagcgaa
     1201 gaatacccac ataaagacaa tgaaacgagt atcctacgga tttaaatcat ttgagaacat
     1261 gagaattaga atctttttga tcaatcaatt aatca
//
LOCUS       DAJSMK010000196         1290 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.207, whole genome shotgun sequence.
ACCESSION   DAJSMK010000196 DAJSMK010000000
VERSION     DAJSMK010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.207"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..1038
                     /locus_tag="ON488_002684"
     CDS             <1..1038
                     /locus_tag="ON488_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HCR3232802.1"
                     /translation="TNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQ
                     KVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEV
                     EVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVS
                     TAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEV
                     TVTLPDGSQYHGTADKNGNFTVKVPKLEAGTKVRVTATDESGNTSEPTNVVVSSNKKD
                     SGKNGSKGSKTDNQDGNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGL
                     LGYKNRKKENE"
     gene            1172..>1290
                     /locus_tag="ON488_002685"
     CDS             1172..>1290
                     /locus_tag="ON488_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HCR3232803.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEIS"
BASE COUNT          519 a          182 c          272 g          317 t
ORIGIN      
        1 accaacacac caggcaatta cgaaggtgtc attgaagtaa cgtatccaga cggtacgaaa
       61 gatacagtga aagttccagt agaagtgaca gacaatcgtt ctaatgcaga taaatacaat
      121 cctgaaggac aaaaagtgac gacagactta aataaagagc cagatgcatc tgagggaatt
      181 aagaacaaag aagatttacc aaaaggaact acttatgctt ggaaagagaa agtagatgtt
      241 agcacagctg gaaacaaaaa aggtactatt gtagtgacat atccagatgg atcatctgat
      301 gaagttgaag tagacgttac agtgacagat actcgttccg atgcagataa atacaatcct
      361 gaaggacaaa aagtgacgac agacttaaat aaagagccag atgcatctga gggaattaag
      421 aacaaagaag atttaccaaa aggaactact tatacttgga aagaaaaagt agatgttagt
      481 acagctggaa acaaaaaagg cactgttgta gtaacatatc cagatggatc taaagaagaa
      541 gtagaagtta ctatttctgt agtagataaa aaagcaccga ataaacctca agttgatcct
      601 attacagagg gtgaccaaat tgttactggt aaaactgaac caaatgcaga ggtaacagtt
      661 acattaccag acggaagtca ataccatggg acagctgata agaatggtaa ttttacagtt
      721 aaagttccta aattagaggc agggacaaaa gtgagagtaa ctgcaacgga tgaatctggt
      781 aatactagtg aacctactaa tgtagttgtt tcttccaaca aaaaagacag tggaaaaaac
      841 ggtagtaaag gtagtaagac ggacaatcaa gatggcaata gcaatcaaga caaaaataga
      901 ggcaaaagcc agtcctcaaa agtttttcct aagacgggag agagtgacag taatatcttt
      961 actattagcg gtggtttaat actgttagga acgttaggat tattagggta taaaaatcga
     1021 aaaaaagaga atgaatagaa aatcaatttc ttaagtcttc tctgagaaga ggaagaatct
     1081 ttttcttcct ctttttgctt ttttatgatg ggaaataagt gttagttaaa gatgaatata
     1141 ctttttatag aaaggaaaag aatgtaatta agtggaaaaa atagtaatta ttggttcaaa
     1201 ccattcaggg ctagccgcag ctcgatttct aaacttaagc gattcaaatt atgaagttat
     1261 tctaatcgat aaaaaatcag aaattagtta
//
LOCUS       DAJSMK010000197         1286 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.209, whole genome shotgun sequence.
ACCESSION   DAJSMK010000197 DAJSMK010000000
VERSION     DAJSMK010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1286
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.209"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            33..>1286
                     /locus_tag="ON488_002686"
     CDS             join(33..474,474..>1286)
                     /locus_tag="ON488_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HCR3232804.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNE"
BASE COUNT          537 a          167 c          224 g          358 t
ORIGIN      
        1 gactagaaat ctaattaaaa ggggtgcttt ttttgcggaa atatacattt gtttttaaga
       61 aaaaagtagt ttcagactat ttaaataacg aaggcggcta caaatatctt gcacataaat
      121 atcaaataaa tcgtacactg gttagacatt gggtaaggat ttataactat catggttggg
      181 aaggcttggt tggaggtggc aaaagctaca ctacaaaatt taaacttgat gttatagaat
      241 atatggaaac aaatggtctt tctatccaag aaactgctaa aaaatttaat atcggttcaa
      301 atagaactct aagtaaatgg atagagcaat atgaagaagg cggtgcttct tcacttgaga
      361 gccaaaaaag gggcagaaaa attagtatga attccaagct aaacattcct aaaaaactta
      421 aagatgagtc tcttgaagaa gaagttattc gtttaagagc agagaacgca tatttaaaaa
      481 agttagaaac cttgattcaa gaacaagatt tgagcaagaa gaaatcaagg ttaaaacaat
      541 ccttcagctc aaaaaagaat ttaaattgaa tctattactt tcaattgcac aattagcgaa
      601 gtcaacttat tattactggg taaaaaaatt agataagcca gataaatata gcaagataaa
      661 gcaagaaatt acagcgattg taaaagaatc aagaaactct tatggttatc gtagagtcac
      721 tttagcgtta aagatgaaag gatatacaat caatcataaa acagttagaa aattaatgtc
      781 ccaaatggga cttacctgtc aaatccgaat aaagcgatat aaatcttata aaggaacagt
      841 aggaaaaatt gccaagaatg tgttaaaacg aaatttttca gtagatacac ccaataaaaa
      901 atgggtgaca gacgtcactg aattcaagat aaaaggaaga aaaatctatc tatctcctat
      961 acttgattta tttaacggag aaataattag ttatagtata tcaactagtc caacatataa
     1021 actgattgaa gaaatgcttc aacaagcaat taaaaaaaag ggaactgagg gttcactgat
     1081 tctacattca gatcaaggat ggcagtatca gatgccacaa tatcaaaaaa aattaaaaga
     1141 gaataacatt attcaaagca tgtctagaaa aggaaattgc ttagataatt ctgtaataga
     1201 aaattttttt ggtgtgctta aatcagagtt tttttatcga gaaaaattcc gatcaattga
     1261 gatatttcaa agtaaattaa atgagt
//
LOCUS       DAJSMK010000198         1281 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.210, whole genome shotgun sequence.
ACCESSION   DAJSMK010000198 DAJSMK010000000
VERSION     DAJSMK010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.210"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(526..726)
                     /locus_tag="ON488_002687"
     CDS             complement(526..726)
                     /locus_tag="ON488_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HCR3232805.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1122..1271
                     /locus_tag="ON488_002688"
     CDS             1122..1271
                     /locus_tag="ON488_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232806.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
BASE COUNT          419 a          226 c          184 g          452 t
ORIGIN      
        1 cggcgaaagc acaaaaaata aaaaaattat tacgttatta aaaaaacaga tgaaagatca
       61 ggttttatta gatctcattc tttcatcact tgaagggatt taatgaacta ctttttcctc
      121 tttgtcgttt ttatatattc gtattccttc aaacagtagg atagcctctt tcaatgcttg
      181 atatttgaac tgtccgttac ttaaaaattt agatgtgccg ccctcttcct agaacatatt
      241 cttttttact ttttcattaa ttgacagacc aatcgaacga aactgtaaat ttcgatagga
      301 taatgattgg tcaaactcat tcattttcaa gacatctcga ttcatattca agataggaat
      361 ctttttatca acatcacttt attcgtattt tcctctacca taaaagcttc acgctccaca
      421 aaattgtttt atacactact attcagccca ttcaacgacc aatgaatttt ttcgtacaaa
      481 aaaaccgtct tttctttcga aaagacggtt aaaagtcaat ttttattaag ctttaacaat
      541 gtttgttgct tgagggccac gttgaccatc ttcaacatcg taagacactg cttggccttc
      601 ttctaaagtt ttgaagccgt caccttggat agctgaaaaa tgtgcaaata catcatttcc
      661 atcttcacca gtgataaagc caaaaccttt gtctgcgttg aaccatttta ctgtaccgtt
      721 attcataaat aaattcctcc tgatacgtat caatgtacgt tttttcgttg caataaatat
      781 ttgataggca aaaggagttt tatctatgta gatatatcgc tcaaattacg tttcaaaata
      841 gattactcat ttaatatatc atgctttttc taataacaca aggataatgc aatgaaatat
      901 aaaattcatt gtcttctatt gtcttcgaat cgaagaaaaa gttgaataac cgcgattgat
      961 tcactttttg ttttcttgtt tatttgcttt tatctgcaac ttttgacttt aaaatttctt
     1021 aactatgaaa acctttcaat tggtggtata cttataaatg gaatttcgtt atcaacgcgt
     1081 tcgttgcctt tcagcaagta tttaaagaaa ggagaatggc tatgacattc tataacaaag
     1141 atatacaata tcgagtaacc ttggatacag atttgaatct atttgtcgtt tttgacaaag
     1201 aaaataccaa tcatgtagcg acaggtgtta cgatcgaaca agcagtgcaa gaattaaaaa
     1261 aatctgcata aggagtggaa a
//
LOCUS       DAJSMK010000199         1260 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.211, whole genome shotgun sequence.
ACCESSION   DAJSMK010000199 DAJSMK010000000
VERSION     DAJSMK010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.211"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            28..501
                     /locus_tag="ON488_002689"
     CDS             28..501
                     /locus_tag="ON488_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCR3232807.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            510..737
                     /locus_tag="ON488_002690"
     CDS             510..737
                     /locus_tag="ON488_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232808.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT          400 a          198 c          211 g          451 t
ORIGIN      
        1 gctatcaaag ataaaagagg gataaaaatg aaatttaaaa cattgctatt aaaatttgtc
       61 gttttaggta taagtgccgt atttattttg ttcggcgtac ttttttatac tcagatcgct
      121 acaagcgaaa aaggattcaa ttttgattgg cagaccacat tatttgtttc tgtcatttac
      181 tttgcccttc tcctagggat cgttattgct tatttcttat tgaaactatt gaaaaaaatc
      241 gaagataacc aagctttttc cactcaaagc ttaaacatac taaaaaaaat cgaacgaacc
      301 attttgttta ttggtttcgc cttttttggc ttacttccta aatttatgaa agtagcggat
      361 ttagacgatg ctccaggttt gatgttggta ggaatcgctg tcgtattcat tccttttgca
      421 gtatacacat taacaagcgt gctggaaaaa ctgcttgaac atgcgatttt acttaagaca
      481 gatcatgatt tgacagtgtg aggtgcgaca tggcaattat cgttaattta gatgtagtat
      541 tagctcaaaa aaaaatgagt gtgactgaat tgagtgagaa agtgggcatt acgatggcaa
      601 acatctctat tctaaaaaat ggaaaagcaa aagccatccg tttttccact ctcgaaaaaa
      661 tctgccaagt tttggagtgt caaccaggtg atttgttgac ctataaaaat gactcgaata
      721 ctataccaga agaataaaat aaagtagaac aaacagtaaa taaaaaataa tctgaatgat
      781 agatgtgtga gacttttaga agttatttac gtctattatt cagatttttt atttcgattg
      841 aataccgttt tatctataaa taagatatgt actgactcat acaaaggggg ccttttcttc
      901 tccatgtact atcacttttc ctgatacaac tggtttcctg ttacgttgta gttggatctg
      961 cttttagtat aatactttat tcattccacc agactgatag cagtttgagc agtctaaata
     1021 atcatgtagt attacaggcc attctgtttc ataccttgaa gtgcttaaaa cttcagctaa
     1081 tggcccattg tgttaactct tactccattc ttttttagta agctcccata tatactgtaa
     1141 agccttctat atattatgtc atgttgcttt ttaacattta ctatgtagtt ttgataaaat
     1201 gatttgaata acagtgatgg acaattcttt tttattttta acattatttt gataataatg
//
LOCUS       DAJSMK010000200         1225 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.212, whole genome shotgun sequence.
ACCESSION   DAJSMK010000200 DAJSMK010000000
VERSION     DAJSMK010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.212"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            254..523
                     /locus_tag="ON488_002691"
     CDS             254..523
                     /locus_tag="ON488_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HCR3232809.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            516..773
                     /locus_tag="ON488_002692"
     CDS             516..773
                     /locus_tag="ON488_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HCR3232810.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
BASE COUNT          473 a          136 c          222 g          394 t
ORIGIN      
        1 aaagaattgc agcaactaaa gcagaagtac ggcaaaagtg aatccaggat tatgtgtatt
       61 gcgttagatt tattgattgc ccaagaaaaa gcaggatttg aggtaccagc actcaaaaag
      121 tgacgtcact ttttatccta aaaactaaaa gtgatagcac ttttaattat aagaagttag
      181 aatattaatc atttgcttaa ttgtacaata taatgtacaa ttgttttata gaaataaata
      241 aggggtgaaa ggaatggaag cagtagctta ttcaaatttc cgccaaaatt tacgtagtta
      301 tatgaaacaa gttaatgagg atgctgaaac acttattgta acaagtaaag atgtagaaga
      361 tacagttgtt gtattatcaa aaagagatta tgattctatg caagaaacgt tgagaacact
      421 ttctaataat tacgtcatgg aaaaaattcg tcgaggagat gaacaattct ccaaaggtgc
      481 atttaaaaca catgacttaa tcgaggttga atctgatgat taaggcttgg tctgatgatg
      541 cttgggatga ttatctttat tggcatgagc aaggaaacaa aagcaatata aaaaagatta
      601 acaagttaat aaaagatatc gatcgttccc cctttgctgg attaggaaaa cctgagccat
      661 taaagcatga tttatctgga aaatggtcca gaagaattac agatgaacat agactgatat
      721 atagagttga aaatgaaacg atatttattt attctgcaaa agatcactat taaccaatcg
      781 gaagtaagga aagggtcaga aacttaaaag tttttgatcc ttattttatt taccctagtc
      841 atttaaaaag ctaatatagc ttagtgttga ttgttattaa tgaatgtgtt tgttacgcgt
      901 attacggata taaggttagt aaaatcattt ctaaagttga ggaaaagtaa atataaatgg
      961 cttaaatttc aacaatttga agttgaatag atatgttata atactattgt agtgtgggat
     1021 gttagttact aaaggatgac gcttatatat atgactgaat agaataagca ataggtttaa
     1081 taatctattt taaatttttt gtactagttt tagttaatta gcaaaaacaa caaaaataaa
     1141 cttctcatag aatttagcta aaaattaatg atttatttac atattaaatt tggatacagt
     1201 taagtaattt ttatatattg gagga
//
LOCUS       DAJSMK010000201         1112 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.213, whole genome shotgun sequence.
ACCESSION   DAJSMK010000201 DAJSMK010000000
VERSION     DAJSMK010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.213"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(62..280)
                     /locus_tag="ON488_002693"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="ON488_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="ON488_002694"
     CDS             complement(546..740)
                     /locus_tag="ON488_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232811.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(840..926)
                     /locus_tag="ON488_002695"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="ON488_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT          390 a          187 c          159 g          376 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aaccgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattata ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt agtacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta ta
//
LOCUS       DAJSMK010000202         1066 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.215, whole genome shotgun sequence.
ACCESSION   DAJSMK010000202 DAJSMK010000000
VERSION     DAJSMK010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1066)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1066)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1066
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.215"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..>1066
                     /locus_tag="ON488_002696"
     CDS             <1..>1066
                     /locus_tag="ON488_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HCR3232812.1"
                     /translation="LFLETEVDKIDIQNKKISCVKKDGTRFSQEYDKLILATGSKQIM
                     LDIPGNNLANIFSIKNFPNAKEIFKALDDNTIKKVGIIGAGYIGVEIAEAIRKRGKEV
                     YLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYLGKEKIEKIVTTRDNK
                     YAMDMVIQAIGFLSHSPIGKKEFLRDVSGAYLTDEYQQTNIKDIYAIGDCATTFFTSI
                     NRSSVDFSISNALRTAYIATQHINDQSFTPSGSQFTNGFSIFGYNFYAAGLNLKTARL
                     LSEAIDYIEIEDYIRPIFSKTNNIVKLRISFEKKAKRIVGVQFYSQEDLSGLLTMFSL
                     AIEEQITLDKLKMLDYLFHP"
BASE COUNT          416 a          132 c          185 g          333 t
ORIGIN      
        1 agttatttct agagacagaa gttgacaaaa ttgatattca aaataaaaag attagttgtg
       61 taaaaaaaga tggcacaaga ttttcccaag aatatgacaa acttatatta gctacaggtt
      121 caaagcaaat tatgttagat ataccgggga ataatttagc taatattttt tcgataaaga
      181 attttccaaa tgccaaagag attttcaaag ctttagatga taatactatt aaaaaagtag
      241 gtattattgg agcaggatat attggagttg aaattgctga agctataaga aaaagaggga
      301 aagaagtata tcttttcgat gttgcagata gagtgttgtc gacctattac gaccgtagtt
      361 tttcagataa agttgaagaa atactatcaa aaaacgggat acatctttgt ctatcagaaa
      421 gtcctaaaaa gtatttagga aaagaaaaga ttgaaaaaat agtgactaca agagataaca
      481 aatacgctat ggatatggtc atacaagcta taggattcct atctcatagt ccaataggaa
      541 aaaaggagtt cttgagagat gttagtggag catatctaac ggatgaatac caacaaacaa
      601 atataaaaga catatatgct attggagatt gtgctacaac tttttttaca tccattaata
      661 gaagtagcgt tgatttttct atctctaatg ctctaagaac ggcttatatt gcaactcaac
      721 atattaacga tcaaagtttt acaccttcgg ggtctcaatt cacaaatggc ttttctatat
      781 ttggttacaa tttttatgca gcaggtttga atttaaaaac agcacgctta ttaagcgagg
      841 ctatagatta tatagaaata gaagattata ttagaccgat tttttctaaa acaaacaata
      901 ttgtaaaatt aagaattagt tttgaaaaaa aagcaaagag aatagtaggt gtacaatttt
      961 atagtcaaga agatctatct ggattattga caatgttctc tcttgctata gaagaacaaa
     1021 ttacattaga caaattgaaa atgttagatt atttatttca tcctag
//
LOCUS       DAJSMK010000203         1062 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.216, whole genome shotgun sequence.
ACCESSION   DAJSMK010000203 DAJSMK010000000
VERSION     DAJSMK010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.216"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(37..993)
                     /locus_tag="ON488_002697"
     CDS             complement(37..993)
                     /locus_tag="ON488_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232813.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgtc aa
//
LOCUS       DAJSMK010000204         1053 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.217, whole genome shotgun sequence.
ACCESSION   DAJSMK010000204 DAJSMK010000000
VERSION     DAJSMK010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1053
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.217"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..638
                     /locus_tag="ON488_002698"
     CDS             <1..638
                     /locus_tag="ON488_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232814.1"
                     /translation="EVIRRIQKDFSCMEEMKYFIQRVEEQLYLESETSQTKVTVSHNR
                     LDVYKRRPETVKKGTELLRLETEKYIMNVYLERSELVENFVSYTICRKHYYSESEYYS
                     IFESMELMEEEMEELNSKDATIDDYYLVFTRFLTCGTESIVLMGMDYELAVPEAFLRE
                     YVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRKRMPYQRFERKKRQ"
BASE COUNT          368 a          174 c          227 g          284 t
ORIGIN      
        1 atgaagtaat cagacggatt caaaaagact ttagttgtat ggaagaaatg aagtacttta
       61 ttcaaagagt cgaagaacaa ttgtatttgg aaagtgaaac gagtcaaacg aaggtcacag
      121 tcagccataa tcgtttagac gtgtataaac gtcgtcctga aacggtaaaa aaaggaacgg
      181 agcttctacg actagaaaca gaaaaataca tcatgaatgt ttacctagaa aggagtgagc
      241 tggtcgaaaa ctttgtcagc tacacgattt gcaggaaaca ctattactca gaatcagaat
      301 attattcaat ttttgagagc atggaattaa tggaagaaga aatggaagag ctaaacagca
      361 aagatgcgac gatagacgat tattaccttg tatttactag atttttgacg tgtggaacgg
      421 aatctatcgt gttaatggga atggattatg aactcgctgt acccgaagca tttttgaggg
      481 aatatgtaga agaagtagat aacccaggcg acgactggta cacgacttta actgattttt
      541 tagacaccta tacttacgac gatacagaag aaatccaaaa tgaacttgac cgtaaacgaa
      601 tgccatatca acgatttgaa aggaaaaaaa ggcaataatc atttataccg aaaagtgaga
      661 atgtgtgaaa taaggacaaa aaacctagta actaagggaa tggttcttat ttcgcaccaa
      721 tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa gcgggcaaca cccgataacc
      781 taagagaaag aaggagatcc atatgaataa aatcattcct ctattgttag tcctatttgt
      841 tggcgaaata cttatgcgcc atgctgcagc tgtgcattta aacttcgtag tatttttggc
      901 aatactggta ttttgtttga tcttttggcg ctttgtatta gcccttgtga gtctactatt
      961 caagatgatt gcagccatat ttttcatagg gttatttcga tgaaaggaga gagtactaat
     1021 gccaattgca ataggaaata aacggttacc cgt
//
LOCUS       DAJSMK010000205         1038 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.218, whole genome shotgun sequence.
ACCESSION   DAJSMK010000205 DAJSMK010000000
VERSION     DAJSMK010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.218"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(165..569)
                     /locus_tag="ON488_002699"
                     /pseudo
     CDS             complement(165..569)
                     /locus_tag="ON488_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
     gene            complement(628..>1038)
                     /locus_tag="ON488_002700"
     CDS             complement(628..>1038)
                     /locus_tag="ON488_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HCR3232815.1"
                     /translation="IAHKVRVKDRKEICDDFKAVYQANSKEEANTFLSSMIEKWKKNY
                     PKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLER
                     FLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          314 a          183 c          171 g          370 t
ORIGIN      
        1 agctatcact ccttgcattc gttttcataa atctattata aaagaaaaga ctgtagatat
       61 catccataaa atggactttg tctacagtct gagacacgac ctaaagatcg tgtctaatta
      121 tgactgtatc agaaaatatg ataccaaacg gatctattca ttaattaatt gacatagttt
      181 atctgttgct cttttatgac tggataactg accaattcat gacgatccaa gtcttcttta
      241 ttcatattta cagcagtaat ttgactgtct tcatacgtac gataataata aatcccttta
      301 tcaacgttac agcaagaaga ataaatcgta tattcgtatt ttccttctcc agtatcgcat
      361 actccttttt gttgctcgac tgagcctagt atatgaaaaa attgactgat actttcagat
      421 tctgaatcac ctgatgcagc attcatttta gtaaatgtgg cttttacaaa tcgagaaaca
      481 gaagagagat ctccaggtaa gcccaatcct cccatcccac gactataaac attcaagctg
      541 atctggtttg aaaaatgatt ttctggtgtt ccattgggag cgtcaataat tttgtgtaaa
      601 taaattgtcc tcctgcaaaa taattagtta ctcagtaaac attgaaacta atgtatcggt
      661 tacctgttga aaacctttat ggcttctgtt tagaaatttt tgattgtatg tatcaaaaat
      721 gctgactaga aagcgttcta gtgattcttc attttgaaac tgctcttttc tacggctgta
      781 tcttttaatt tgcttattga aagactcgat tagattggtt gagtaaatgg ttctacgaat
      841 gctaggtgga aaatcataaa aagttaataa gtcttggttt tctatgagtg actgcgtcac
      901 tttaggatag tttttcttcc atttctcaat catgctggat aagaaggtat tcgcttcttc
      961 ttttgagtta gcttgataaa cagccttaaa gtcatcacag atttcttttc ggtctttgac
     1021 acgtacttta tgagcgat
//
LOCUS       DAJSMK010000206         1038 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.219, whole genome shotgun sequence.
ACCESSION   DAJSMK010000206 DAJSMK010000000
VERSION     DAJSMK010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.219"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..>1038
                     /locus_tag="ON488_002701"
     CDS             <1..>1038
                     /locus_tag="ON488_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HCR3232816.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKH"
BASE COUNT          361 a          204 c          187 g          286 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacacc
//
LOCUS       DAJSMK010000207          991 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.220, whole genome shotgun sequence.
ACCESSION   DAJSMK010000207 DAJSMK010000000
VERSION     DAJSMK010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.220"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(21..94)
                     /locus_tag="ON488_002702"
     tRNA            complement(21..94)
                     /locus_tag="ON488_002702"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="ON488_002703"
     tRNA            complement(108..181)
                     /locus_tag="ON488_002703"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="ON488_002704"
     tRNA            complement(209..281)
                     /locus_tag="ON488_002704"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="ON488_002705"
     tRNA            complement(301..374)
                     /locus_tag="ON488_002705"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="ON488_002706"
     tRNA            complement(384..457)
                     /locus_tag="ON488_002706"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="ON488_002707"
     tRNA            complement(468..553)
                     /locus_tag="ON488_002707"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="ON488_002708"
     tRNA            complement(570..641)
                     /locus_tag="ON488_002708"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="ON488_002709"
     tRNA            complement(653..725)
                     /locus_tag="ON488_002709"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="ON488_002710"
     tRNA            complement(743..824)
                     /locus_tag="ON488_002710"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="ON488_002711"
     tRNA            complement(832..904)
                     /locus_tag="ON488_002711"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="ON488_002712"
     tRNA            complement(908..980)
                     /locus_tag="ON488_002712"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DAJSMK010000208          943 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.221, whole genome shotgun sequence.
ACCESSION   DAJSMK010000208 DAJSMK010000000
VERSION     DAJSMK010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.221"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..>943
                     /locus_tag="ON488_002713"
     rRNA            <1..>943
                     /locus_tag="ON488_002713"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAJSMK010000209          930 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.222, whole genome shotgun sequence.
ACCESSION   DAJSMK010000209 DAJSMK010000000
VERSION     DAJSMK010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.222"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..382
                     /locus_tag="ON488_002714"
     CDS             <1..382
                     /locus_tag="ON488_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="2-dehydro-3-deoxyphosphogluconate aldolase"
                     /protein_id="HCR3232817.1"
                     /translation="NSLRYLEFREGAFDFQTSQQNLLTIPGAMSPTEIFKMFEMGADI
                     VKVFPANCLGPEYFNQVQAPLGSLPLMAVGGVDQTNAQNYLNNGASYVGIGSKFFEKS
                     AVHQLNYERLMELAESFIDSLRVE"
BASE COUNT          299 a          161 c          174 g          296 t
ORIGIN      
        1 taacagccta agatatttgg agttcagaga gggcgcgttt gattttcaaa cttcgcaaca
       61 gaaccttcta acaattcctg gggccatgtc gcccacagag atattcaaaa tgtttgagat
      121 gggtgctgat attgttaagg tgttccccgc caactgtctt ggaccggaat atttcaatca
      181 agtgcaagcc cctttaggaa gtttaccttt gatggctgta ggaggggtag atcagactaa
      241 tgcacaaaac tatttgaaca atggagcctc ttatgtagga attggttcaa aattttttga
      301 aaaaagtgct gttcaccaac taaattacga gaggctaatg gagttggctg aatcttttat
      361 agatagttta agagttgaat agaacccatt tgcggaatac aacttgtttt ataatatggc
      421 gttatctgta taaaacatag tatcacagtg aatgagattg aactggtaga ttgatttttc
      481 gaccagttct ttttgcgcgc tctgatgctt gatatattcc caacgagata aaaaatcccc
      541 caagatacta agatgaagcg tttatccaac ctcatactta gataaaaagg aggaaatgtt
      601 ctgaatgata aacaaaaatt agcgcgcaca atttggcgat gaaaaaatca tattgtattt
      661 acgtcaaaat atcaccatca aattatttat ggaaaacata ataggcataa acccgattgc
      721 tcggctacta tgtggacaca attatagttt taaagataag tttcaattac ttattttaca
      781 cctcttcttt agggataaaa cttttcctaa cggtcaattt tgcgccgatt aatgttttct
      841 ttgatatgtc ccgcgaatat accagttgat cacttaataa atctacacag gttttagcta
      901 tctcttcgat atctatctta aaagttgtaa
//
LOCUS       DAJSMK010000210          881 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.223, whole genome shotgun sequence.
ACCESSION   DAJSMK010000210 DAJSMK010000000
VERSION     DAJSMK010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.223"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            62..>881
                     /locus_tag="ON488_002715"
     CDS             62..>881
                     /locus_tag="ON488_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HCR3232818.1"
                     /translation="MHKISVIVPAYNVEDYLENCLESISNQTHSNIEIIVVNDGSPDR
                     SGEIAEEYKKKDMRLKVIHQVNGGLSAARNSGLDSATGDFVCFIDSDDWIEPDYLELL
                     YFGTQTYGADISVLKIKKISSLEQLKEHTIAERKWEIFDREQAMKNLFINNKIGYSAN
                     NKLFNRNLFDNIRFPLGKLMEDKATTYLLIDHSEKVAVNSSAKYHYYQSPKSILRGSF
                     NPRIFDSFEVHEDILIFIDKFYPELSINVRTRYVYEAIRMMMTMIKNNYTNKEDY"
BASE COUNT          342 a          111 c          160 g          268 t
ORIGIN      
        1 ttgttactgg taatgataca tttgtaaaaa taaaaaagat gatttttagg aagtgaagag
       61 agtgcataaa attagtgtta tagtacccgc atataacgta gaagactatt tagaaaactg
      121 cttagaatct atttccaacc agacacattc aaatattgaa ataatagtag tcaatgatgg
      181 ttccccggat cgaagtgggg aaattgcaga agaatataaa aagaaagata tgcgattaaa
      241 agtgatacat caagtgaatg gtggtttaag tgcggctagg aattctggtc ttgattctgc
      301 aacaggagat tttgtgtgct ttattgacag cgatgattgg atagaaccag actatcttga
      361 gttactatat tttggcacgc aaacttatgg agcagatatc tcggtgctaa aaataaaaaa
      421 gatttcaagt ttagaacaac taaaagaaca tacaattgct gagagaaaat gggaaatatt
      481 tgatagagaa caagcaatga aaaacttatt tataaataat aaaattggct attctgcaaa
      541 taataaatta ttcaatagaa atttatttga taatataaga ttcccactgg gtaaattaat
      601 ggaagataag gctactactt atttgctgat cgatcattcc gaaaaagttg ctgtcaattc
      661 atctgctaaa tatcactatt accaaagccc taaaagtata ctgagaggaa gcttcaatcc
      721 tagaattttt gattcttttg aagtccatga agatatacta atattcatag ataagtttta
      781 tccggaatta tcaattaatg ttagaactcg ctatgtctat gaagcaataa ggatgatgat
      841 gacaatgatt aaaaataact ataccaataa agaagattat t
//
LOCUS       DAJSMK010000211          823 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.224, whole genome shotgun sequence.
ACCESSION   DAJSMK010000211 DAJSMK010000000
VERSION     DAJSMK010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.224"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            22..>823
                     /locus_tag="ON488_002716"
     CDS             22..>823
                     /locus_tag="ON488_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HCR3232819.1"
                     /translation="MPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILT
                     FLTGISSRDGEKFPVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTD
                     YDFAHLLFSDGSITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVIS
                     TFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDD
                     LLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT          253 a          142 c          186 g          242 t
ORIGIN      
        1 cgaggagggt ggaaagaaac cttgccagaa attgcggatg aaatcagtat cctcaacttg
       61 acgagtaagt cagaaaatca aggtctgctt gatccttatg tgattatgaa gaaaaagaaa
      121 gactcggaaa gtttagcaat tgatattctg acttttttaa caggaatttc aagtcgagac
      181 ggggagaagt ttcctgtgtt acgtaaagcc attcgaacgg tgactcaaag tgatcaacgg
      241 gggttattac aagttattaa cgaattgcga aaagacgggt caccaatcgc ggaaaatatc
      301 gccgatcata tcgagtcctt taccgattat gattttgctc atttgctttt ctcagacggc
      361 tcgattaccc aatcgattag tttagataaa cagctaaata tcattcaagt ggcggatttg
      421 gttttaccgg atgcagaaac gacttttgaa gaatatacca ccatggaatt gcttagtgtt
      481 tcgatgctaa tcgtcatttc cacttttgcc ttggacttta tccatagtaa ccgagaaatc
      541 ttcaaaattg tcgatttgga tgaggcttgg agttttcttc aagtggctca aggaaaaacg
      601 ttatcgaata agcttgttcg tgctggtcgg gccatgaatg ctggggtcta tttcgtcact
      661 caaaatagcg acgatttatt agatgaacgt ttaaaaaata atatcgggtt gaagtttgct
      721 tttcgcagta ccgatattca tgaaatcaag aaaaccttgg aattctttgg tttggatcag
      781 gaggatcaaa gcaatcaaaa acgcctgcga gatttggaaa acg
//
LOCUS       DAJSMK010000212          795 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.225, whole genome shotgun sequence.
ACCESSION   DAJSMK010000212 DAJSMK010000000
VERSION     DAJSMK010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.225"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            7..624
                     /locus_tag="ON488_002717"
     CDS             7..624
                     /locus_tag="ON488_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232820.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT          309 a           97 c          146 g          243 t
ORIGIN      
        1 agaaccttgg gttttcaagt gctttttggt tcattaatct taaccatagt gtttttaaag
       61 tggaaaacaa gcaacaaaaa aagtatgtgg agccttgtag gaatagttct tattattttt
      121 actgtgactg cagcaacaga agcaaattat tcgcataaaa ttcagtcgta taaaggtcgt
      181 ttagttatga ccaaaaaaga tgttacacgt tatacatcct caagaactgg aggcctatat
      241 gactatgcac cattagatgc attgaaatat aaagatcatt taaagaaaca tgaagtaaaa
      301 gttggtgatc ggtgggagaa tgcatctcat aaagcatata attccaaaat agtctataca
      361 gtagaagatg ccgatgagca aaatatcaca ttacctgtat tcaattattg gggaacagtt
      421 gtgaaagtaa atgggaaaaa gagcactata gaaaatgaca atggtttagt gtctattaaa
      481 ggtacgggga aaagaactat agttgaggtt tcatctacgt atccaactac gatgattcta
      541 tctttattaa ttagttcaat aacttttata ttcttattta cacgttattt aataagatgc
      601 tgcggtgaaa tgaaaataga ttagatagat attataaata tgttgattct attttcatag
      661 caatggagaa aatacattag caatatataa aagaaggtat caagagtcac agtgaattta
      721 ttccgaaaag tgaaaagagc aaatataaaa tttaatgaaa atatagaact aaataggaaa
      781 acgtagacgt aattt
//
LOCUS       DAJSMK010000213          769 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.226, whole genome shotgun sequence.
ACCESSION   DAJSMK010000213 DAJSMK010000000
VERSION     DAJSMK010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..769
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.226"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(95..454)
                     /locus_tag="ON488_002718"
                     /pseudo
     CDS             complement(95..454)
                     /locus_tag="ON488_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          228 a          139 c          155 g          247 t
ORIGIN      
        1 aataaaaagg atcaaaaatg tagtgacccc caaaagttag acttttttgg agtggagaaa
       61 tccactcttt ttttcatgct ctaaaatgat atttttacac aaccgtaacg gttgttttac
      121 gaaattggac gggactttgc cagtttaatt tctgttttat ccgttcatta ttgtagtaat
      181 agatatagct atcgatggct gattttaatt cctcgaaaca gttataaact ttcccgtgaa
      241 aaatctcttg ttttaataag ccaaaaaaat tctccataag tgaattatct aagcagttcc
      301 ctttccgaga catgctttga aagattttgt actccttcaa tttgtttcta taagctttca
      361 tttgatacga ccaaccttga tctgagtgaa acgtacgacg atagggacaa tcgttagtgg
      421 tctggatagc ttcctccaaa ccttccatta ccgcacgtgt ttctgaatgg tggtagcgac
      481 cgatttgaac ggctagggcg gaaatacggt gcaaatgcac ggtggtttca tgcaatgctt
      541 acagggcgta ttttgtaagg gtatgtaacg gagataatcc cgacggtaat ggatgtgaga
      601 ggccaagccg acgctgacgg tagggcaaac aaacatagtt gcactctagc gatcgttatt
      661 tatttttaac ggtcaaacta gggtacaact atgcttaaaa cacttcgcct caacttctgg
      721 tagcaaaagt gattttgaaa gtcaaaatat tttttatgag ttatttata
//
LOCUS       DAJSMK010000214          765 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.227, whole genome shotgun sequence.
ACCESSION   DAJSMK010000214 DAJSMK010000000
VERSION     DAJSMK010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.227"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            660..>765
                     /locus_tag="ON488_002719"
     rRNA            660..>765
                     /locus_tag="ON488_002719"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DAJSMK010000215          761 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.228, whole genome shotgun sequence.
ACCESSION   DAJSMK010000215 DAJSMK010000000
VERSION     DAJSMK010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..761
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.228"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            51..731
                     /locus_tag="ON488_002720"
     CDS             51..731
                     /locus_tag="ON488_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HCR3232821.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIK
                     YLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEI
                     KVLLGIPA"
BASE COUNT          270 a          127 c          152 g          212 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tattcatgga aaatggatga aacgtacatc aaaattaaag
      301 gaaaatggca ttatttgtat cgagccatcg atgcagatgg tttaaccttg gatatttggt
      361 tacgtaaaaa acgggacaca caagcagcct atgcttttct taagcggtta gtgaagcagt
      421 ttgatgaacc gaaggttgta gtcacagata aagccccctc tattacaagt gcctttaaga
      481 aactaaaaga atacggcttt tatcaaggga cagaacatcg taccattaaa tacctgaata
      541 atttgattga acaagaccat cgtccagtaa agagacgcaa taaattctat cgaagtttac
      601 gcactgcctc taccacgatt aaaggcatgg aagccattcg aggattatat aagaaaaccc
      661 gaaaagaagg cactctcttc gggttttcgg tctgtactga aatcaaggta ttattgggaa
      721 tcccagctta aatcatagat accgtaaggg attttattct t
//
LOCUS       DAJSMK010000216          744 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.229, whole genome shotgun sequence.
ACCESSION   DAJSMK010000216 DAJSMK010000000
VERSION     DAJSMK010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.229"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
BASE COUNT          248 a          127 c           93 g          276 t
ORIGIN      
        1 actattcatt gatcataacg attggctatt tgattgtatc aaatctagga aatatggtat
       61 ttggtatcag taaagaattc agttggacta ctacattatg ggaatctcta ttctttttca
      121 tcttcgtatt tttgttacaa aattatcgaa aaaaataaac atgtgccatc tatctgttgg
      181 cacatgtttt aggatttatg gtacttttta ttcggcaatc cattttattt ttctacttct
      241 tcttaatacc tctaacactt ttgatttata aactaatcca atgcatctac ttgcgcttat
      301 taagctattt cagctagata gtaccacccc atgcgtcaat gcttgatttt ccttttgtat
      361 aacattgtat aagcaataaa ggacaaataa gtggtgatta caccaaacca ttgaataaga
      421 aaaattctga tacgtaaata aacatgaact tgaaaaaatt aatgaatcgg ttagctacta
      481 cgtagttgtc ttttttctca tacagttctg ttaacttaca cttctcttcg ctagataata
      541 aaaaatcctc caactgtatt gtccaatata atcccaggca tctaaactag cattatagaa
      601 gagacacaca tagaatctaa aataactggt tttaaatgtt tcttacaatc aaaaaaagct
      661 gttaaatgca ctccacacct tcatactcta tcatttttta taaacgatat atttttattg
      721 tttttcgata aaaaatagtt gttt
//
LOCUS       DAJSMK010000217          668 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.230, whole genome shotgun sequence.
ACCESSION   DAJSMK010000217 DAJSMK010000000
VERSION     DAJSMK010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.230"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..446)
                     /locus_tag="ON488_002721"
     CDS             complement(<1..446)
                     /locus_tag="ON488_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232822.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT          197 a          118 c           90 g          263 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt
      601 tttatttggc ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc
      661 atttttat
//
LOCUS       DAJSMK010000218          638 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.231, whole genome shotgun sequence.
ACCESSION   DAJSMK010000218 DAJSMK010000000
VERSION     DAJSMK010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.231"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            73..234
                     /locus_tag="ON488_002722"
     CDS             73..234
                     /locus_tag="ON488_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HCR3232823.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            253..>638
                     /locus_tag="ON488_002723"
     CDS             253..>638
                     /locus_tag="ON488_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232824.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRN"
BASE COUNT          266 a           62 c          109 g          201 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcagga taaggataag tgtattaatt gtggaaaatg taaaaaagtt
      121 tgccaaatga ataaagattc agttgagaat tgcaatcatc tggagtgtat cagatgtgga
      181 cgatgtaaaa atgcttgtcc agtggatgca attagttatg gagtaagaaa atagagagga
      241 gtagttagga aagtgataaa aaatgctata gcatatatta caagaaagaa aaatagaact
      301 ttaataattt ttatcatatt aactatagtt ctttcttgct tgtattcttg tttaacaata
      361 atgaaatcaa gcaatgaaat agaaaaggct ttatatgaaa gttctaattc ttcaatatca
      421 ataacaaaaa aagatggtaa atattttaat gttaatcaat ttaaagatat tgaaaaatta
      481 aaagaaattg aagaaaaaat aattcaatat gatggattag caaaactaaa agatgctaaa
      541 gtagttagcg gagaacaaag aataaataga gaagatttat ctgacgaatt taagaatgtt
      601 gtttcactcg aagctacaaa taatactaaa agaaatat
//
LOCUS       DAJSMK010000219          635 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.232, whole genome shotgun sequence.
ACCESSION   DAJSMK010000219 DAJSMK010000000
VERSION     DAJSMK010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.232"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            302..559
                     /locus_tag="ON488_002724"
     CDS             302..559
                     /locus_tag="ON488_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232825.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          264 a           92 c           89 g          190 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaatatt tttctgtcca cgttcatatt
      181 actccaaagt tttcctcatt ccaaaagaaa agcacagaat acacaaagaa gcgtttttat
      241 ttgtataaac tatatcaaag ttctatactt aaattatcaa ataaaaagga cgtgaagata
      301 aatgtcaaaa ttagaaaaca aagaagaaaa agttgtaaac aaaattgttt ctgttgtcaa
      361 taaactggat aaagagttag acgaacttga tacgttatct gaaaatccag aaaaaaaaca
      421 taacctaaaa aaatggttag ttgaacgaaa ggctattcat gaaattaaaa aagttcttca
      481 tgaagctgat aaatatgaaa aatatgatga aaaagaactt gacaaagaat ttaaagaaat
      541 caatgactta ttactataat tgatttatac gactcatttt tgagtcgtca gactgcaaac
      601 aacactctaa atttaggagt ttgtctacag tctga
//
LOCUS       DAJSMK010000220          595 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.233, whole genome shotgun sequence.
ACCESSION   DAJSMK010000220 DAJSMK010000000
VERSION     DAJSMK010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.233"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..580
                     /locus_tag="ON488_002725"
     CDS             <1..580
                     /locus_tag="ON488_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HCR3232826.1"
                     /translation="GIKSHLWVTQNIWGDHTDPCGYLSEMGVSKEKLAYDLAHGFTDD
                     NPTTSDDNPTTSEDKPVIDPTRAGAANSTLTDGTNYAHVDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          204 a          106 c          122 g          163 t
ORIGIN      
        1 aggaatcaaa tcgcatttat gggtaacaca aaatatttgg ggcgatcata cagatccttg
       61 cggttatctt tctgaaatgg gtgtaagtaa agaaaaacta gcctatgatt tggctcatgg
      121 ttttacggat gataatccaa ctacttcgga tgataatcca actacttcgg aggataaacc
      181 agtaattgat ccaactcgag caggtgctgc aaattctacg ctgacagatg gaacaaatta
      241 cgcccacgtt gatcagttcg gagaaatcga aaacgcaaac ttgcatgtag ctggatggca
      301 cattgctaat tataaatacg agtatatttt cattatggac tacaatactg gaaaagaact
      361 agctagagta agagctgatg ggatttatag accagacgta aatcaagctt ataatacttt
      421 aggaaatgtt ggctatcatg tatctttcaa tatgcgtgat ttccctaata agaaagtata
      481 cgtcatgatg cgtgcgacaa acgatccaga aggaaatact aagggtggag cacaagattt
      541 tcatgacaag cgttggtatt taaatattcc acaacgataa aaaattcccc cctct
//
LOCUS       DAJSMK010000221          526 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.234, whole genome shotgun sequence.
ACCESSION   DAJSMK010000221 DAJSMK010000000
VERSION     DAJSMK010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.234"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..508
                     /locus_tag="ON488_002726"
     CDS             <1..508
                     /locus_tag="ON488_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
                     /protein_id="HCR3232827.1"
                     /translation="DLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFS
                     RIKQPLTEVEIFHTDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLK
                     VEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELG
                     CANASEAV"
BASE COUNT          158 a           94 c          112 g          162 t
ORIGIN      
        1 agacttgact tatgtacgag tcgggaaaaa atggaattat gtctgtttca ttttggatct
       61 gttcaatcga gaaattctcg gctattcttg tggagaacat aaagatgccg ttctagtaaa
      121 aaaagcattt agccgtatca aacaacctct gacagaggtt gagatttttc atactgatcg
      181 tggaaaagag tttgataacc aagctattga tgaattatta acaacttttg acatcaatcg
      241 atcattgagt cataaaggct gtccttttga taatgccgta gctgaatcaa cttataagtc
      301 gttgaaagta gaatttgtct atcaatacac atttgaaacc ttacaacaat tggatttgga
      361 gttatttgac tatgtcaatt ggtggaacca ccttcggttg cacggtacac ttggctacga
      421 gacaccggtt ggttaccgta accagagatt ggcgcagcga atccttgata atgagctcgg
      481 atgtgctaac gctagcgagg cagtctaact ttaactgtta gctcct
//
LOCUS       DAJSMK010000222          496 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.235, whole genome shotgun sequence.
ACCESSION   DAJSMK010000222 DAJSMK010000000
VERSION     DAJSMK010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..496
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.235"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(<1..331)
                     /gene="tnpB"
                     /locus_tag="ON488_002727"
     CDS             complement(<1..331)
                     /gene="tnpB"
                     /locus_tag="ON488_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HCR3232828.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAIL"
     gene            complement(321..>496)
                     /locus_tag="ON488_002728"
     CDS             complement(321..>496)
                     /locus_tag="ON488_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232829.1"
                     /translation="VPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINNYI
                     LQAILKELLSNAL"
BASE COUNT          146 a          107 c           88 g          155 t
ORIGIN      
        1 gcaaaatagc tcgaggttga tcgatactta atccttctaa caaccatcga acctgttggt
       61 tcgttaaggt tcgaacttcg tctttcgtcc gaggccattt taacttgccg ttttctatcc
      121 gcttataaca gagaagaaaa ccatcaccgt cccaatagag aagtttgaaa cggtcttgac
      181 ggttcccgca aaataaaaaa acggcatctt cgtaaagctc gagttgatac tcttgttgaa
      241 taagactggc aagaccatca attccttttc gcaaatctgt ttttccgcac acaatataaa
      301 tatgtttggt ttgaagtaaa tcataaagca ttggacaaca gttctttcaa aatagcttga
      361 agaatataat tgttaatacc gttatagatc aaaacttcag aaccattctc tcttttgatg
      421 cgcatcgcta acttggcagc cgcgggttta cctttttctg gtgcactctt ttcgtttcct
      481 aattggacag gaacaa
//
LOCUS       DAJSMK010000223          494 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.236, whole genome shotgun sequence.
ACCESSION   DAJSMK010000223 DAJSMK010000000
VERSION     DAJSMK010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.236"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            1..268
                     /locus_tag="ON488_002729"
                     /pseudo
     CDS             1..268
                     /locus_tag="ON488_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751573.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
BASE COUNT          184 a           73 c           87 g          150 t
ORIGIN      
        1 atctatattt tgatatacaa attacagctt cagatactaa gttgcataaa ccttttccgg
       61 accccataca aaaggcaatt gatgaattgg gcataaaaaa taagaaacga tttatattgg
      121 tgattcatta tatgacatgc aaagtgcgaa agcttgtggg atagcatttg gtttagctaa
      181 atggggagcc aaaaatatag aaaattttca aagtgtagat ataattattg attctcctca
      241 agaaatactt gatttgttag aaaaatagac aaagagcgtg agataaggat agggtctcac
      301 gctctttgtt tttcgccatt taaagattga aatttttgcc atcgccgatt gtaaaattaa
      361 gctagacaac taaaaaagtc atttgtgcta cactcaaaat agttccgacc aaagaattat
      421 aaggagtgag tacaaatgac ctatacccat cttacaacgg atgaacttgt aataatagag
      481 tcttatttca aaat
//
LOCUS       DAJSMK010000224          492 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.237, whole genome shotgun sequence.
ACCESSION   DAJSMK010000224 DAJSMK010000000
VERSION     DAJSMK010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.237"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            55..492
                     /locus_tag="ON488_002730"
                     /pseudo
     CDS             55..492
                     /locus_tag="ON488_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          200 a           82 c           95 g          115 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aa
//
LOCUS       DAJSMK010000225          471 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.239, whole genome shotgun sequence.
ACCESSION   DAJSMK010000225 DAJSMK010000000
VERSION     DAJSMK010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.239"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            47..>471
                     /locus_tag="ON488_002731"
     CDS             47..>471
                     /locus_tag="ON488_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HCR3232830.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT          150 a           87 c           85 g          149 t
ORIGIN      
        1 ttatcttgaa tttgtatatt acttaacaaa agataatgga gtgtgaatga tggagaccat
       61 aacgtattcc cctttgaact tatttacgaa ttttcaagaa gctgcagcta acttttccga
      121 gaccccgatt atctttgatg agccactttc agctttccca gaattaggac ttgaaacaac
      181 ttacaaaaaa tgctgcgaaa gtgtgttgaa acgggcttat caattggctc atcttggagt
      241 gaaatccgga gacaaagtta ttatttataa gagttccgct tttgacacat accttctagc
      301 tgtttctgtg tcttaccttg gtgcagtgcc tgtcatgact tcttatcatc taccaacaac
      361 aacaatggaa gtatttatcg atcgtttaga agaccctttc attttatttg atgatgagac
      421 aaaaaagcga gtgagagaaa tttcaaatgg aacaaaatca aaacagattc c
//
LOCUS       DAJSMK010000226          468 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.240, whole genome shotgun sequence.
ACCESSION   DAJSMK010000226 DAJSMK010000000
VERSION     DAJSMK010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.240"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..>468
                     /locus_tag="ON488_002732"
     CDS             <1..>468
                     /locus_tag="ON488_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HCR3232831.1"
                     /translation="CVIWGIINGYTSQRATYRAVCSVLFPNGDFPSRSRFTRLSSNLA
                     YTIKIIRYFFIKKLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYF
                     YGLKIHMIVTKTGFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          155 a           86 c           83 g          144 t
ORIGIN      
        1 cttgtgttat atggggcata attaatggct atactagcca aagagccacg tatagagcgg
       61 tttgttccgt cttatttcct aatggtgact ttcctagtag gagtcgattc actcgcttaa
      121 gttcaaactt agcttacact atcaagatta ttcgatactt tttcatcaag aagctcacca
      181 aaggtgaact agtcggaatt atagatagtt ttcctagtcc attatgtaaa ccagttagaa
      241 atagacaagc aaaactattg aatcaaatag ccaaagttgg ctataactca acaaaaaaat
      301 cttattttta tggtcttaaa attcatatga tcgttactaa gactggcttt ccgattactt
      361 actcaatcac gaatccaggt gtccatgacg tgaaagtgtt agagacttta tcggaagaag
      421 cgaatcttcc caatatccta ggggacaaag gatatattag ccataaaa
//
LOCUS       DAJSMK010000227          459 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.241, whole genome shotgun sequence.
ACCESSION   DAJSMK010000227 DAJSMK010000000
VERSION     DAJSMK010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.241"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            52..417
                     /locus_tag="ON488_002733"
     CDS             52..417
                     /locus_tag="ON488_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232832.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
BASE COUNT          128 a           89 c           68 g          174 t
ORIGIN      
        1 atttacaata aaactaacaa aataataaca cttgttaggt ggtgatgaaa gatgataaaa
       61 acttgctgga aaaaccttcc gttgctttta tcttttgttc cttatgtgca tttcgcctta
      121 ctgcttgatt ttcgttatca ttccgtaagc gggttcatca cattgatatt tttatctctt
      181 tttgctggat attattttca aaggaacagg cgtattatat ctttattcat tgccaatatt
      241 atatctactg tcacttccta tttattttgc gccaatttta ctgaatggcg ttacttctat
      301 catcctttaa aaccgaccca gctgatcttg cttcttgcag gtatttactt agttccacaa
      361 atccttgggt cgttatgggc ggtagcctta tcttataaaa aagctcggca tccataaaaa
      421 caaaccatat atgtacaaag agaagctact ttcttcttt
//
LOCUS       DAJSMK010000228          455 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.denovo.242, whole genome shotgun sequence.
ACCESSION   DAJSMK010000228 DAJSMK010000000
VERSION     DAJSMK010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.denovo.242"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            25..411
                     /locus_tag="ON488_002734"
     CDS             25..411
                     /locus_tag="ON488_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HCR3232833.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT          165 a           66 c           99 g          125 t
ORIGIN      
        1 taaaaataaa aaaggagatc tttcatgaaa aaaattttag ggttgatcgt tatcatattg
       61 attgctttta taggatggaa aggttgggac tactatcagt ctacttatgt aggtaaagat
      121 tattatgcgg tagtcaaagc tccaatgcct gcagaaactg atatcaaagc agataatggg
      181 gaagtaattg gaagaggttt taaatacaac gtagatgctt atgctgaaaa cggtgaaaaa
      241 agacagttag atttcgatgt cattacttct ggtgactctg ccaatggttc tgcttacccc
      301 gaaggaacga tcttgcagtt gaaagcaagc gaaaagcgga tcatagagaa aaaagtaatt
      361 accagcgata aggtaccctc atctgtaaaa gaaaaattag gcctatctta agctaagaat
      421 atatcgcaaa aaagcactcg aagtgagtgc ttttt
//
LOCUS       DAJSMK010000229        23728 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.034, whole genome shotgun sequence.
ACCESSION   DAJSMK010000229 DAJSMK010000000
VERSION     DAJSMK010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23728
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.034"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..212
                     /locus_tag="ON488_002735"
     CDS             <1..212
                     /locus_tag="ON488_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HCR3232834.1"
                     /translation="ELEQEESIRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSST
                     HRGPSELCGNVFKIEYTKKRQRLAY"
     gene            447..683
                     /locus_tag="ON488_002736"
     CDS             447..683
                     /locus_tag="ON488_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232835.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            690..2642
                     /locus_tag="ON488_002737"
     CDS             690..2642
                     /locus_tag="ON488_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HCR3232836.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="ON488_002738"
     CDS             complement(2714..3211)
                     /gene="dfrG"
                     /locus_tag="ON488_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HCR3232837.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3573..4613
                     /locus_tag="ON488_002739"
     CDS             3573..4613
                     /locus_tag="ON488_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HCR3232838.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            4711..4899
                     /locus_tag="ON488_002740"
     CDS             4711..4899
                     /locus_tag="ON488_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HCR3232839.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(4957..5310)
                     /locus_tag="ON488_002741"
     CDS             complement(4957..5310)
                     /locus_tag="ON488_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232840.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            5841..6263
                     /locus_tag="ON488_002742"
     CDS             5841..6263
                     /locus_tag="ON488_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HCR3232841.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            6260..6490
                     /locus_tag="ON488_002743"
     CDS             6260..6490
                     /locus_tag="ON488_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232842.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            6988..7188
                     /locus_tag="ON488_002744"
     CDS             6988..7188
                     /locus_tag="ON488_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HCR3232843.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            7215..8408
                     /locus_tag="ON488_002745"
     CDS             7215..8408
                     /locus_tag="ON488_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HCR3232844.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="ON488_002746"
     CDS             complement(8476..10041)
                     /gene="guaA"
                     /locus_tag="ON488_002746"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HCR3232845.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10100..11023)
                     /locus_tag="ON488_002747"
     CDS             complement(10100..11023)
                     /locus_tag="ON488_002747"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HCR3232846.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            11219..11824
                     /locus_tag="ON488_002748"
     CDS             11219..11824
                     /locus_tag="ON488_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3232847.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12132..13148
                     /locus_tag="ON488_002749"
     CDS             12132..13148
                     /locus_tag="ON488_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HCR3232848.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            13289..14590
                     /locus_tag="ON488_002750"
     CDS             13289..14590
                     /locus_tag="ON488_002750"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HCR3232849.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            14636..15298
                     /gene="deoC"
                     /locus_tag="ON488_002751"
     CDS             14636..15298
                     /gene="deoC"
                     /locus_tag="ON488_002751"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HCR3232850.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            15319..15717
                     /locus_tag="ON488_002752"
     CDS             15319..15717
                     /locus_tag="ON488_002752"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HCR3232851.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            15783..16865
                     /locus_tag="ON488_002753"
     CDS             15783..16865
                     /locus_tag="ON488_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HCR3232852.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17077..18639
                     /locus_tag="ON488_002754"
     CDS             17077..18639
                     /locus_tag="ON488_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HCR3232853.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            18632..19765
                     /locus_tag="ON488_002755"
     CDS             18632..19765
                     /locus_tag="ON488_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232854.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            19765..20721
                     /locus_tag="ON488_002756"
     CDS             19765..20721
                     /locus_tag="ON488_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HCR3232855.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            20820..21986
                     /gene="deoB"
                     /locus_tag="ON488_002757"
     CDS             20820..21986
                     /gene="deoB"
                     /locus_tag="ON488_002757"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HCR3232856.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            22010..22828
                     /locus_tag="ON488_002758"
     CDS             22010..22828
                     /locus_tag="ON488_002758"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCR3232857.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            22845..23552
                     /gene="deoD"
                     /locus_tag="ON488_002759"
     CDS             22845..23552
                     /gene="deoD"
                     /locus_tag="ON488_002759"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HCR3232858.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
BASE COUNT         7720 a         4202 c         4949 g         6857 t
ORIGIN      
        1 tggaactcga acaagaggaa agcataagat ttcagaattg ttctctgttc cctctttatc
       61 atggaagtgc aaaaagtaat atagggattg ataaccttat agaagttatt actaataaat
      121 tttattcatc aacacatcga ggtccgtctg aactttgcgg aaatgttttc aaaattgaat
      181 atacaaaaaa aagacaacgt cttgcatatt aagtagttca gttttggagt acaaaaagtg
      241 aaaatgtaaa cctaaatgag tatcaaattg caactgaatt tgatactcgt tttttattgt
      301 taaatcaacg tttgttgtta atttacacca caaaatgtaa gttaaaatgt atataaaaat
      361 gcgaacgtga aataattatt gtaggaatgc aaattggtgt gttaaaatgg ttacaattta
      421 ctaagcaaaa aggggtgcat tttcctatgc aatttcttga gccaaaaaat aagaacgcta
      481 agtctgtgga ttgggaaata tcagagcaag taagggtgat agttaagcaa tacgctgaat
      541 atgcagagcg tactgaaagc gaagcagtgg atgaattctt attgaacatt ttagacgata
      601 agaagtttat tgaatggatt gccaacaagc gaagtaataa gcggattgtt gaaaaaatgg
      661 gtatcaaaga tagagtgggt tgatagacaa tgaccaagct taaaagatta gccacgaagg
      721 aagatgaaat tgtagatgtt aaaattccga tttcaaacga agaattaaaa gatagggcta
      781 aacaatatga tttattaact ccaaaacgat ttgcaacaag gtataacaaa atgttgttct
      841 tgccaacgtc ttttaaatgg aacggttctg aatatcccat tcaatataat tactgcatca
      901 atccgttttg ttgtaatttt gggaaagaac agcacaaatt caaagatgta aaagggaaac
      961 caagtcgata taaaatgact ggtagttcca aagataaagg tcataaaggt atgtactgca
     1021 atgacaatcc tattggcaga ggtgtatcgc aaaactgtac agtaacccct ttatctaatt
     1081 ggtctgttgt tgaagaaatt aaacgcctta tagaaatcaa tagcatccaa gatgttgagc
     1141 cagattatca atttcataaa gaaggctgct cggaagaaga atcaacccca ttcaatgagc
     1201 cgaagcaatt ttacaaaagg gggaaaagta ggggcaaatc tcaacgctat caatgtaagg
     1261 cgtgtaagaa gttcactaat gttctaccaa aaagagaaga aaccactact tatcaccaac
     1321 aaaagaacac cattcttcca atgttcgcta agatggttgt tggaagggtt tcagtcagtc
     1381 gtacttgtga tattttagga attggagttg gaacctacta tcataagctg gagtggctgt
     1441 ataggcgttg tttggagttt ttagaacgat atgagacaca accccttcaa acaaagaaat
     1501 ttaacgagat gtggcttaat acggacaaga tgcactacta cctaaataac gtccgtaaga
     1561 aaggacaagg ttcaaagaaa tatacggggt ttgaagacct taatatgcaa acgtatatag
     1621 ttgtatctgc tgaggtctta tcaagatatg tgttccgttc tgatgttgcc tatgattgga
     1681 atatttcaat ggatgaatta aatgaagata caagaaaatt caaagaagac catctcaata
     1741 cttttagtcg taaaaatgat aggttagatt ggtcttatta tccacaagaa ccatccgcta
     1801 acgatagcga aaataggaat gcttatcttc acgaattagg gaaaattact aataggagta
     1861 gatttgtcga tggtttaaat gttgatgctc cttatactac aactgctcac tattggttaa
     1921 ttaaacaaat ggttaatgcc gacgaatggc gaatgattag tgatgatgac ttctctatta
     1981 gaaacgcctt ttatagagta ttcacgaaag aattaaggtt gagcgatgca catcatttta
     2041 tttgccaagt taacaagacg aaaagcagaa aacaatgctt aaaagaattc ggacaagcaa
     2101 aagcagaact gctcgattgg ggagatatca gaggattcaa aacaaagttt ctacggactt
     2161 tggcatctca ttatctaact gaattactaa caagtcatca attccacgaa gaggctatta
     2221 gtaaagatgg agaaagatat cgcaaatatg ccgataaccc tatcaaacat ccattagcca
     2281 ctaaggataa aggattttat tcagttgatt gtagaacgga tttatctgct ctggaaccaa
     2341 acgaaatcgc aaagatgcta ttaaatgtta atgaccattc gaccaatagc tttattcaac
     2401 agataagacg ttatatatca tctcttgaaa gaccattaac aacagctcgt ggtgataaga
     2461 agagctatat ttacgctaac ttcaatccga agtatgctca atttgcgatt acaattctaa
     2521 gaacttacta caacttttgt cgccctttta aatcagcgga taaaaaggtt ttgacacctg
     2581 ctcaaagatt agggattaca gataaacaat ttgattggaa agatataatt tatttcaaat
     2641 gacaaaaaga gcttggagta atcccaagct cttgtgcttt atctttactg ttcttcttca
     2701 attaacgcac ccgttaactc aataagtttt ttctttcata tacatgaaaa tagtagttat
     2761 acggattttt atcattcttt atcccttttt gggcaaatac ctcattccat tcctcataat
     2821 tcacttctgg aaaaaaagta tctccttcga attcatgatg tatttttgtg atgtacattt
     2881 tctcaacata agggaaaaac aaattataaa tctgttctcc tccgaaaata aaaatttctt
     2941 cttcgttttt acataactca aaaacatctt ctattgaatg aacaatttca caaccattaa
     3001 aggtaaaccc cttatctctc gtcagaataa tatttcttct gtcaggtaag gctcttccga
     3061 ttgattcaag gttcttccta cctaatatta tcggatgtcc ctttgtagta tttttaacat
     3121 attcccagtc cttgggaatc ctccaaggaa tgtcattctc tttgccaatc actctattct
     3181 tatccatcgc agcaatcaaa gaaactttca tttataacac agccttttta actaatttac
     3241 catctaattt cttatttcta tcaaaaaacc ttttctcatt atcctgcccg ttagttgaat
     3301 aagcaatttt ttctataagt tatattatca taataccaca aaatcacaaa ttttcattca
     3361 attatcattt tcaattgcat tttataaatc attttgtatg taatttggta tgtaagttaa
     3421 aatgaaaaaa gtagtccatt ttgaagtaca ttttgtcatt ttgtactcca aaactgaact
     3481 acttacttgc atatatacgc ctttatagtg gagtactaca tttacgagat tcggttagag
     3541 tatcagaaaa agaaaaaata aaagttacag aaatgtatac ttcaataaat ggtgaattat
     3601 gtaagattga tagagcttat tctggagaaa ttgttatttt gcaaaatgag tttttgaagt
     3661 taaatagtgt tcttggagat acaaaactat tgccacagag aaaaaagatt gaaaatccgc
     3721 accctctact acaaacaact gttgaaccga gtaaacctga acagagagaa atgttgcttg
     3781 atgccctttt ggaaatctca gatagtgatc cgcttctacg atattacgtg gattctacga
     3841 cacatgaaat tatactttct ttcttaggga aagtacaaat ggaagtgatt agtgcactgt
     3901 tgcaagaaaa gtatcatgtg gagatagaac taaaagagcc tacagtcatt tatatggaga
     3961 gaccgttaaa aaatgcagaa tataccattc acatcgaagt gccgccaaat cctttctggg
     4021 cttccattgg tttatctgta tcaccgcttc cgttgggaag tggaatgcag tatgagagct
     4081 cggtttctct tggatactta aatcaatcat ttcaaaatgc agttatggaa gggatacgct
     4141 atggttgcga acaaggatta tatggttgga atgtgacgga ttgtaaaatc tgttttaagt
     4201 acggtttata ctatagccct gttagtactc cagcagattt tcggatgctt actcctattg
     4261 tactggagca agcctttaga aaagctggaa cagaattgtt agagccatat cttagtttta
     4321 aagtttatgc accacaggaa tatctttcac gggcatataa cgatgctccc aaatattgtg
     4381 caaatatcgt aaatactcaa ctgaaaaata atgaggtcat tattattgga gaaattcctg
     4441 ctcgatgtat tcaagattat cgcaatgatt taactttttt tacaaatggg cttagtgttt
     4501 gtttagcaga gctaaaagga tatcaggtta ccactggcga acctgtttgc cagacccgtc
     4561 gtctaaatag tcggatagat aaagtaagat atatgttcaa taaaataact tagtgcgttt
     4621 tatgttgtta tataaatatg gtttcttatt aaataagatg aaatattctt taatatagat
     4681 ttgaattaaa gtggaaagga ggagattgtt attataaact acaagtggat attgtgtcct
     4741 atttgtggaa ataaaacaag actacgaata cgagtggata ctatacttaa aaatttccct
     4801 ttatactgcc ccaaatgtaa gaacgaaact ttaattaatg ttcaaaaaat gaatataata
     4861 acaatcaaag agccagacgc caagacgcag agccgataat ttgagaaatg aaactctcat
     4921 cttatcggct ctttttgttt atctgaattt tactgactag ccttcaatat ttcttgcttc
     4981 attgatacct tttgctagtg cttccattaa ggatagttct ttgtctgtaa agctatccat
     5041 gtatttttct acctgtaacc ttcgagtgct tttaatcaaa ttatctgtag gtaagaaaaa
     5101 ttcatcaata gatacatgga gtaatgatac aagatcatac agcacttgtg tacttgggtg
     5161 ttgtcctttg ttttctatat ttgttaaata acgtgggtca atttcaatca ttgttcccac
     5221 ttgttcacga gtgagacccc gtttcattcg agcctcttta atcgctaaac caacggctct
     5281 aaaatcgtat ttatcttctt ttttacgcat actaaatcac ctctatacat tttactgttc
     5341 ctatataacc ataaacaggt atagaaaaac atgttatata gtttatgagt tcctatagaa
     5401 cactgtggaa tttattaatg cgatgaatcc aatttcaaat agaaaggtcg ctgattttat
     5461 ttacctatac aactttataa aatttagtca tactcctaga aagtagataa aattggcgac
     5521 ttaatggagg gaaaagtcgc catgagaaag ataatctgtc atctagttct cttaattaag
     5581 ttcttatcaa aaaaacttat ccacctgtac tggatagata tgaccatcaa tgtggttttg
     5641 cagattacat agatagaaaa atcaaagcat atgaacagag aaaacaatct gtttatgtgc
     5701 ttttttggtc acttaataaa tatcttttag gatttctctt catttatgca acaaatcccc
     5761 cgttcgtgtc ggggtttagt atgaagggag ataaagaagc acatgccact ccctttcacg
     5821 acagaaaggg ggtgaaaagc atgaaaccat cttcttttca agaaaccata gaaaatcagt
     5881 ttgactatat ctgcaaacaa gttattgaag atgaacgaaa agattacttc aaacatctag
     5941 acagactatc agcaaaagaa gtctcgtttt ctgatataga taactacctt gtcaactctt
     6001 tttctactgt tgatacgtac gtcactgatt tccaactatt taaattattt ggattaagaa
     6061 tcaatgttga aagtgattta ttaagtgaag ccctgcgtca tctttcagag aaaaaacgga
     6121 acattatttt acttcattac tttatggata tgagtgatgt ggagattgcg gagttactaa
     6181 atttgaatcg ttcgactgtt tatcgtcatc gaataagtgg actagccatg attaaagaat
     6241 tcatgaagga gtgtaaagaa tgaaaacagc ttatccaagg gttcccttcc ccctcattgt
     6301 aaaggcgaca gatggcgacg tggaagcaat taatcagatt gttaaacatt atcgagggta
     6361 tacctcaaaa cgttcattac gtcgcatgac agacgaatat ggaaattctc atatggttat
     6421 tgatgaaacc ctacgtggca gaatggaaac gaaactcatc tctaagattt tatcgttcga
     6481 aattaaatag tcccattttt tcgtggaagc gtgtcgaatc gtatccacgc ttcccgattt
     6541 gggaggtttg ttattccatc aaagcatatt gtgtgttcag taggttttga taggctaaca
     6601 agccaaacgt tctttgacaa ccaaataaag gcaatcgaat acgtttcggt aagaaaagag
     6661 ctgatgaact aacacgccat gacctacaaa attagtgagc gattcatgtt agtaattcga
     6721 aagtaatctt tagcaggatt gctgccatga ctttcttatc gtgataatga tactcccgta
     6781 tagccatagt ccgagcgtta gaagcgtcac aggcaatggg tacggctaca tgagaaccat
     6841 gcagaagtga aattcctgtg agctttgcta gagctgttcg attgctaaga tattcttctc
     6901 ttgtcagtgt attattataa aactatttga tataattata ggtgaatatt ggagttttcc
     6961 tagcctataa ttgggaaagg agtaataatg ataacggtca caaaaaagga tttagttgag
     7021 ctaggatatg gaacttcttt ttcagcagac atcataaaaa aagcaaaaga attgatgatt
     7081 acaaaagggc atatctacta tcaatctcga aagctagata gagtccctcg tgaagctgtt
     7141 gaagaaattc taggaattcg gttttcaaat gaaaacaggt ctgagtagtt tttgcacagt
     7201 aaggagtaaa aactatggtt aaagacccaa taaaaaaagc aaagaatgga acctattatt
     7261 ttcgtgcaaa tctaggttat gattctaaag ggaaaaaaat tcaaaaatat cgtagtggat
     7321 tcactactaa aaaagaagca agagaagaat attcgaaact gctattgatg aaaccagaag
     7381 aattaagtga gaataaggat aaaatgacgt ttaaacatta tatctttgaa attttccttc
     7441 catggtataa gacacaggta aagctcagaa catatgaaaa tcgcttacca actattaaga
     7501 agcatttctc ttattttgat aaaatggctg tttccgatat tgagcctatt gatgtgcaaa
     7561 attggcaact aaaattatca aagaagtgta agtcttctta tgtaagagct gttcaaggac
     7621 tattttcagt tgctatggat cgagcaattg tccttgggat aaccaccaca aatccatcta
     7681 agattattgg caatgtgaaa aagcaaaagt ctaaaattga attttggaca aaagaagaat
     7741 ttgaaaaagt aatctctcta atttacaaag aagattacta tcaacacttt ttatttatct
     7801 ctctgtggtt tttatttatg actggaatgc gaattggtga agctactgcc attcaatggg
     7861 aagatattga ttttgactca ggagtactaa ccatcaacaa aacactctat tacaagaatc
     7921 aatcgaatta tagatttgtt gaaccaaaaa caaaggcgag cgttcgtcat attgtattag
     7981 ataaatgcac attaacttat ttatccgaat ggaaggaagt acaacaaaat ctaattcaga
     8041 cagactttgt aatgagctat aacggtattc ctacccaaaa acatacacta tcatatgcta
     8101 ttgaacgcta tgctaagctg gctggtatcc atcgaatcag aatccatggg ttacggcatt
     8161 ctcatgcttc cttgttaatc agtatgggag aaaatccact tatcattaaa gatcgtctag
     8221 gacacgaaga tattgagacg actttaggaa cgtatggaca tctttatcct aacagtaatt
     8281 tcgaggtagc taacaaatta aatggagcca tttcctttaa agaagcaaaa caaaattatg
     8341 atacttcacc aaagaatcaa tttactgtag actacttgcg aaacaaagaa atgaaaaaag
     8401 tgcaataaaa gtgcagtaaa aagataagaa gagccagaaa cccttggtat aagaggattt
     8461 ctagctctcc tacaactatt cccactccac tgttgctggt ggtttagaag tgatgtcata
     8521 cacgatacgg ttgacgtggg ctacttcgtt tacgatacgt acagagattt tttgcaagac
     8581 ttcccatggg atacgggcaa agtcagcggt cattccgtcg attgaagtta cagcacggat
     8641 accgactgtg tagtcgtaag tacgtccgtc acccataaca ccgacagagc ggatccctgg
     8701 aagaacagtg aaatattgcc agatatcacg gtcaagtcca gcagctgcga tttcttcacg
     8761 caagatagca tcagattcgc gtacgatttc tagcttgtct tcagtgattt cgccaagaac
     8821 acgaatacca agaccaggac cagggaatgg ctgacgccaa acgattgaat caggcatgcc
     8881 taactgagtc cctaattcac ggacttcgtc tttgaataat gtgtttaatg gttcgatcaa
     8941 ttcaaattgc atatcttctg gcagtccacc tacattatgg tgagatttga tcgtctgtgc
     9001 tgtttctgta ccagattcga taacgtcagt atacaacgtt ccttgtgcta ggaaagagac
     9061 gccttcttca ccagcaagtt ttgttgcttc gtcatcaaaa acatatacga attcattccc
     9121 aatgatttta cgtttttgtt ctgggtcaga tacacctttc aacttgtcta agaagcgatc
     9181 tcttgcatcg actttgatga tgttcaagcc gaattttccg cctagacttt ccattacttg
     9241 ttccgcttcg cctttgcgta gcagaccgtg gtcaacaaag atagatgtca attggtcacc
     9301 gatcgctttt tgtaaaagaa ccccaacgac actagaatca acgccacctg aaagaccaag
     9361 caagactttt ttgtcaccaa cttgttcacg gattttttct acttgcatat cgataaagtt
     9421 atccattgtc cagttacctt cacagtgaca aacatcaaag gcaaagtggc gcagcaattc
     9481 gattccgtat tcggaatgac gtacttctgc atggaattgg ataccataaa aattacgtgt
     9541 tgtgtcttgg atagaagcaa tcggacaatc tttgcttgtt ccgactgttt caaagccttc
     9601 aggaacttta gttaccaagt caccatggct catccatact gtttgttgtt ttggtgtttc
     9661 tttaaacaag acagcttgat cgcttgttac ttctaacaag gctttcccat attcgcggtt
     9721 tttagcaggc tctacggaac cgccaagttt gtacgtgatc aattgcatac catagcaaat
     9781 ccctaataca ggaataccta aattgaagat ctcaggatcg atcccaaatg cattctcatc
     9841 atatacactg tttggtccgc cagaaagaat gattcccttt ggattcatcg cttttacttc
     9901 ttctgcagta atgcggtggc tcaataattc ggaaaagact ccaagatcac gaatacgtct
     9961 tgtgatcaat tggttatact gactaccgta gtctaatacg ataatctttt caacgttcgt
    10021 catatcggca acgtttgtca aatttattac ccctatccct ttaaatttta tctcaaaata
    10081 gtcaaactat tttaaaatgc taatattttc gcatgaaaat cgaatcgatg atatgatttt
    10141 cagttttatg gagaattata tcggctcttc ctcgtgtagg caagatatat tcctgtaaat
    10201 ttttcaaatt cacatttttc catacatctt ttgccatttt aaaggcttct tcacgatctc
    10261 cgatagcaaa acgataataa taattctctg gattttggaa agccgtatcc agtaacgcac
    10321 caaaacgatc caaataccat ttttcgatca gcacgggatc ggcatcgaca tagacagaaa
    10381 aatcaaaaaa gtcgctgacg tagatttgct gattcgcagg taattgaagc gtattgatcc
    10441 cctcaacgat caagatatca ggctgctgga tcaattcgta cttgtctgga atgatatcat
    10501 acacatcatg tgagtaaaca ggtactttta tctcttcctg accagatttt acacggttca
    10561 agaaatcgat cagcatctcc atatcataac tttcaggaaa tcctttacgg tccatgattc
    10621 cacgctcttt taatatacga tttggataaa gaaatccgtc agtcgtgatc agctgaacgt
    10681 ttcttcgttt gaaggtacga gacaaaatcg tctgcagcag tctggctgtt gtactttttc
    10741 caacggctac acttccggcg atcccgataa taaaaggcgg tacttctacg tatttatgaa
    10801 gaaataaacc tttactcaag aacaaagatt caaattcttt catataaaga taaatcagat
    10861 gagcaagagg tacatagata tctcgaacat cctgcatgga aatgcggtca ttcaaacttt
    10921 tgatattatc tagttcatct tgtgtcaaag gtgcttgccc attacgataa aattctcgcc
    10981 attcttctct tgccacacgg tagtagttca ttggatcatt catattagcc tcctgcgttc
    11041 tcccatcaat ggaactattt taacacaaaa taaacgcaaa ccccaccact taagagagat
    11101 tgccgatctt tttgtataat ctttataata gaaagaaacg gagtcttatt cttgacttgc
    11161 gcacggatac ataaaaggat agactgttgt catgaaagaa atgagaagga tggaagacat
    11221 gacaaatcat tactattctg aacgcccaga tacggcgcac gattttgaac aatgggcttt
    11281 tgagttaaaa ggcagaacct ttcaatttgt aacagattct ggtgtatttt cacgtgaaac
    11341 agtggattat ggttcacgtg tcctgattga tgctttcgat tgggaagagt tacctgatga
    11401 aggaaagatc ttagatgtgg gatgcgggta tggaccgatt gggttagctt tggcatttgc
    11461 gacacagcgg tttgttgaaa tggtcgacat taatgaacga gcggtaagtc tagcgcaagg
    11521 aaacgcaaag cgtaaccaaa tcgaacatgt tgatatccat caatcgaata tctatgaagc
    11581 agttcatgaa gaaacctatg cagctatcgt aagcaatccg ccgatccgtg ctggaaaaaa
    11641 agttgtacat gaaattttga caggcgcata tcctcggttg aagaagggcg gtacactgac
    11701 aattgtgatc cagaagaaac aaggagcgcc gagtgcgcaa aagaaaatgg aagaaacatt
    11761 tggtaatgca gaaatcgtca caaaagataa aggatattat atcatcaaaa gtgtgaaaga
    11821 ataactagct gaaaaatagt ggagcgacga aagagtggaa ctgggcgtgc atgtacgggt
    11881 acgtatcagt tctttttttg ttgagaagtt tttaaaaaca aagaactatt ttttcttcaa
    11941 aaagaaatag taggaacaga gtcgttgttt tttacgataa aataaataag atacagaact
    12001 tgtatagaag gctgccaagt cggtagataa aggaggtttt tatcaaaaaa catactttcc
    12061 ttttttctct attcttttct tgggggtttt ggtacactga tagggaattt agatagaagg
    12121 gagccaatag gatgaagctg accatcagag atatcgcaga aatggcaggc gtatcagtaa
    12181 caactgtctc acagattttg aataacaaag gaagcagatt tagtgataag acaagaaaaa
    12241 aagtgttgtc gatcgtgaat gaacatcatt ataagcccga ttatttcgct tcaaatgtga
    12301 tcaatcgaca ttcaaagacc atcggaatga tcgtccctga tgtcactgat ttcttcttct
    12361 ccaaactgat cgaaggtgta gagagctatt tgaatccttt gggctatgtg atcatgttat
    12421 gcaattctcg tcatagccaa gaaaatgaga tcaagtattt acaagagctt tcccaccgct
    12481 cagtggacgg aatcttgctg gccacaccaa atattttacc tgagaaatat gcattagaca
    12541 gcggttttta tcaaaaaatg ccaatcattt taatcgatcg cggattgaat cgtcgggata
    12601 acggacggct tatcgtaaag gaatatgagg gcgcctatca agctgtttcg ctgtttattg
    12661 aaaatggcca tacgaagatc ggcatgctga aggaaaccac tggatactat caattagaag
    12721 aacgtttcaa cggatatcgt catgcgctga aagatcatgg cctgcctttt aatgggaaat
    12781 ttgttgaaca tggagagttg actgtccaag gtggatatac tgcatcaaaa aaattactca
    12841 aacataaaga tatcacggct attttttgcg ggaatgatgc catggcgatc ggatgctatc
    12901 aggcgatcga tgaattgggc aaaaaaatcc cagaagatat ctcagtcata ggattcgatg
    12961 gattaaagct gtcagaatac atgattccgc aattgacgac agtgcagcag ccaagttttg
    13021 atattggatt ttatgctgca cgtttcctga tcgatacgat cgaatttcct caaagaaaag
    13081 ttccgaacaa agtgttcgaa acaaaattaa ttattcgtga gagcgtaaaa gtattgacaa
    13141 agggctaact cggcggtata ttgcttatgt aagcatttac aaaggctagt tagtgctttt
    13201 tttattttta gtaaaccagt ttactaaagt ggtttacctt tcctaaaaat aatgtataat
    13261 accgaatgaa gacaaggagg atcaggcaat gcgaatggtg gatctgattg aaaaaaagag
    13321 ggatggaaac gagctgtcga aagaggaaat cgagtacatc gtcacgaact atacgaatgg
    13381 aaagattcca gattatcaag tcagtgcatt attgatggca attttttatc aagacatgac
    13441 aaatgaagaa atcacgaact taacattggc gattgctaat tctggtgatg tcatcgattt
    13501 gagttctctt gaaggaataa aggtagataa gcattcgaca ggtggcgttg gtgacacgac
    13561 cacattgatt ttagcccccc tagtagctag tgtcggagtg acagtggcta aaatgtctgg
    13621 acgcggtcta ggttacacag gtggtacact agacaagcta gaagcaattc ccggatttca
    13681 gatcgagctt tcggatgaag aatttgtacg cattgttaat gaaagtaaag tagcggtaat
    13741 tggtcaatca ggaaacttgg caccggcgga caaaaaattg tatgccttgc gtgacgtcac
    13801 agcgaccgtt gattctcttc cgctgattgc cagttcgatt atgagtaaaa aaatcgcggc
    13861 aggagcagat gcaatcgttt tggatgtgac cactggagac ggtgctttca tgaagaacat
    13921 cgaagatgca agacgtctgg caaagaccat gacgagcatt gggaaactgg ctaaccgaga
    13981 aacagtggcg gttatctcag atatgtcaga acctcttggc gaagctatcg gaaatagtct
    14041 agaagttgtc gaggcaatcg aaacattaca aggaaatggt ccagaagatc tagtagaaat
    14101 gtgctacgcc ttaggaagcc aaatggttgt tcttgctggc aaagctaaga caaccgatga
    14161 agcaagaacg ttgcttcaag aagctctgga atcaggtaaa gcgttagcaa aattcaaaga
    14221 aatgatccaa aatcaagggg gagacccagc gatcgtggaa catccagaac gaattttgac
    14281 tgcacgctac acaatggagc ttcctgctaa acaaagcgga gttgtgtcaa aaatcgtggc
    14341 aaatgaatta ggaattgctg caatgatgct aggtgctggg cgtaaaacca aagaagaaga
    14401 tattgatcac gctgttggat tgaaactgca taaaaaaatt ggtgacactg tgacaaaagg
    14461 tgagtcacta ttgacgatct atagtaacga cgaagaaatc acttctgtca ttgaattatt
    14521 atataaaaat attgaaattg gtgaatcggc aatgaagcca acgttgattc atgacatcat
    14581 cacagaataa aggaaaaaag cggactttac cgttttaaag aaaaggggaa aagaaatgga
    14641 actaaaccga atgatcgacc atactatttt gaaagcagac gcatctaaag aagctgtgat
    14701 gcaaattatc gaagaagcaa aaaaatacca tttttattct gtctgcatca atccagcatg
    14761 ggttgcgcta gcgaaagaac aattacaagg tgagccagta gccgtatgta cagtaatcgg
    14821 gtttcctcta ggagcaaaca cacccgagac aaaagcattt gaaacaacag atgccatcaa
    14881 taacggtgca gatgaagtcg atatggtcat caatatcggt gctttgaaat caaaggatga
    14941 tcaacaagtc caaaaagata tcgaagcagt tgttgaagca gcaaaagatc gtgcgcttgt
    15001 caaagttatt attgaaacat cgttattaga tagagaagaa atcatccgag cttgcgaaat
    15061 agcaaaagct gcaggcgctg attttgtcaa aacatcaact ggtttctcaa caggcggagc
    15121 aaaggtagag gatgtccgtt tgatgcgtga aactgtagga ccagaaatgg gtgtcaaagc
    15181 ttccggcggt atccataacg aagaagaagc aatggcaatg atcgaagctg gtgctacaag
    15241 aatcggaaca agcgcaggag tagcaatcgt atctggttca actggtgaag gctattaatt
    15301 ttttcaaagg agaagctcat ggcagaactc aaacaagaat ggatcaacac agctattgaa
    15361 gcgttagata aagcctatgt tccttattcc cattttccgg taggcgcttg tctcgtaacg
    15421 gaatcaggca agatttatca aggcatcaac attgagaatg catcatttgg attaacgaat
    15481 tgtgccgagc gcacagcttt tttcaaagca gtatctgaag gagaaaaaac atttacgcat
    15541 ctagtcgtag cggggcacac ccccgatcct atctctcctt gtggtgcatg tcgacaagta
    15601 atggcagaat tctgttcccc tgatatgccg gttacgctag taggagacaa tggtgtgacg
    15661 aaggcaacga ccgttcgtgc actgctgcct tatgcattta ctgaaaaaga tctataactc
    15721 atgttcattc agtcagctga ctgttgaaaa ataaaacaat tattttagga ggctttacag
    15781 aaatgaaaaa agcaaaatta tttggtttag gtgctgtcgc actagcagca gggttatttt
    15841 taggtgcatg cggcaacaac ggctctactg attcatccgg tggcaaaagc tcatcagaca
    15901 caacaactgc agcattgatc acagacacag gtggtgtaga cgaccgttca ttcaaccagt
    15961 cagcttggga aggactagaa aaatggggga aagatcaagg actttcacga ggaaatgatg
    16021 gcttccaata tttccaatct tcaaatgaat cagattacat cccaaatatt gaccaagcat
    16081 tgaatgctgg attcaaaacg atttttggta ttggttataa actaaaacca gcgatccaag
    16141 aacaagcaac aaacaataca ggtacgaact ttgttattat cgatgatgtc atcgatggat
    16201 tagataacgt tgtatctgca actttcaaag acaacgaagc ttcttatctt gcaggtgttg
    16261 cagcagctta tacgactgaa acaaacgtag tcggctttat cggcggtgta aaaggtgaag
    16321 taatcgatcg ttttgatgct ggattcaaag ccggtgttga tgcaggtgcg aaagaattag
    16381 gaaaagaaat caaagtattg aatcaatatg ctggtgactt ctctgctcca gataaaggac
    16441 gttcaattgc tcaaggtatg tatgcacaaa acgcagatat catcttccat gcttcaggcg
    16501 gtacaggtaa cggtgtattc caagaagcaa aatcattgaa cgaatcaggc gacaaaaaag
    16561 tttgggttat cggtgttgac cgcgaccaat cagacgaagg cgaatacaca ttaaacggcg
    16621 aaaagaaaaa cttcacattg acatctacac tgaaagcagt tggaacagta gtagaagatt
    16681 tggcacaaaa atcagcggac ggtaaattcc ctggcggcga acacactgtt tatggattga
    16741 aagaagacgg tgttggtcta acagaaggac aactttctga cgaagcgaaa aaagcagttg
    16801 atgaagcaaa agaaaaaatc atttcaggtg acgtaaaagt tccagaaact cctgaagaaa
    16861 actaaaacca tttctatagc cttgttagac acatgtttga caaggctatg gtttgattag
    16921 aacaagaatt gttcatttat ccaagctgcc ttgtgacagt ttggataagg gaacaactcc
    16981 ctgaagtaat gtttgtttca aaagaagaac gctcactaag cgtgaatctt agtcaatcgt
    17041 tgccctagat agaaatcgtt aggatgtgaa aaaaaggtgg ttcaagaaaa tattgtcata
    17101 gaaatgcaga atattaccaa agaatttgga acattcaagg caaatgacaa catcaattta
    17161 caagtaaagg caggagaaat tcatgcgttg cttggagaaa acggtgctgg caaatctaca
    17221 ttgatgaacg tgctttccgg attattagag ccgacatcag ggaaaatttt gatgcgtggg
    17281 aaagaagtaa agatcacaag tccgaccaaa gccaaccaat tagggattgg gatggtccat
    17341 cagcacttta tgcttgttga tgcctttact gtaacagaaa acatcgtgtt gggaagcgag
    17401 cctagtcgcg cagggatgct tgaccataaa aaagcacgaa aagagatcca aaaagtttct
    17461 gaacagtatg gattgtcagt caacccagat gcttacgttc gtgatatttc agttggaatg
    17521 gaacaacggg tagaaatttt aaaaacactt taccgaggag cagatgtact gatttttgat
    17581 gagccgacag ctgtattgac ccctcaagaa attgatgaat taatcgtgat catgaaggaa
    17641 ttagtcaaag aaggcaagtc gatcattttg attacgcata agttagatga aatcaaagca
    17701 gtagctgacc gctgtacagt tatccgccgt ggaaaaggaa tcggtacagt caacgttaaa
    17761 gacgtaacct cacaacaatt agccgatatg atggttggaa gaacggtttc attcaaaacg
    17821 atgaaaaaag aagcgaagcc tcaagaagtc gttttgtcta ttgaaaatct agtggtgaaa
    17881 gaaaatcgtg gattagaagc cgtgaaaaac ttgaacttag aggttcgtgc tggcgaagta
    17941 cttggtatcg ctggaatcga tggaaacggg cagtcggagt tgatccaagc tttgactggt
    18001 ttgcgaaagg cagaaagcgg acatatcaag ctaaaagggg aagacatcac taataaaaaa
    18061 ccccgaaaaa tcactgaaca tggtgtagga cacgtgccag aagaccgtca taaatacggg
    18121 ttagtcctag atatgacatt atctgaaaat atcgcactac aaacctatca tcaaaaacct
    18181 tacagtaaaa acggcatgct gaattattca gtaatgaatg aacatgccag agaattgatc
    18241 gaagaatatg atgttcgaac aacgaatgaa cttgttcccg caaaagcttt atcaggcgga
    18301 aatcagcaaa aagcaattat cgctcgtgaa gtcgaccgag atcctgatct gttgattgtt
    18361 gcaaatccaa ctcgtggact ggatgtaggt gcgatcgaat ttattcataa acgtctgatc
    18421 gaacaaaggg acaaatacaa agcagtgtta ctgatcagtt tcgaattaga agaaatttta
    18481 aatgtttcgg atcgtattgc tgttatccat gaaggagaaa ttgtcggtat cgttgatccg
    18541 aaagaaacat ctgaaaatga attaggtcta ttgatggcgg gctatacctt agaagaagca
    18601 cgaaaagagt tagaaaaggg ggctggcgca catgaatgat cgcagcgaaa aattccgtaa
    18661 tttattagtg cctgtacttt cagttgtttt aggattgatc ttaggcgcga tattgatggc
    18721 tgcttttggt tttcagccca tccaaggtta ttcttctatg ctagatgcag cccttggttc
    18781 gcaaagaggg ataggtgaaa cgttaaggca agcaacgccg ttgattttta cagcattagg
    18841 tttttctgta gctaactcag ctgggttttt caatattggg ctttctggac aagcactttg
    18901 cgggtggatc gtcagtgtct gggtggcact tgcgtttcca gatctgccaa aagttgtttt
    18961 gcttccgtta tgcgtgatct taggtgcctt agctggtgcg atggcagcgg ctgttccagg
    19021 tttacttcga gcattttttg gaacaagtga agtgatcgta acaatcatga tgaactatat
    19081 cttattatac gtaagcacat ttgctttaca tgaagtgatg cctgaaagct atcgctcaag
    19141 tttggactct tccaatatga tcagtcaaaa tgcctcactg cggttaccat ggttaacaca
    19201 agcttttggc ggctctcgcg taaactcagg attattttta gcaatcatcg cgcttatttt
    19261 cgtttggctg ctgatgaaga aaacgacttt aggatttgaa atccgttctg ttggattgaa
    19321 tccttttgct tctgagtatg caggaatgag tagtaaacgt acgatcgttt tgtcgatggt
    19381 catttctggc gctttggcag ggcttggcgg tgtggttgaa ggattaggaa cgtatcaaaa
    19441 cttctttgtt caaacgactt cgctatctat tggatttgac ggaatggctg tttccttgct
    19501 tggttctgga tcagcaatcg gtattctttt atcagcgatc ttgttcagta ttttgaagat
    19561 cggtggactt ggcatgcaga caggagcagg tgttccgttt gagatcgtca atgtatcgat
    19621 tgctttgatt atcttctttg tcgggatcaa cttcctgatt cgtttcgtca tggctaaagt
    19681 cttccaaggg aaaaaacaag aagagatcgt tgcgacaata gaatcgaaac caacgaatca
    19741 aaaccatgaa gggggcgaac tataatgtcg actatcgaat taattgcctt gatccttact
    19801 tctacactgg tttattcaac accgctaatt ctaacgtcac taggcggaac tttttctgaa
    19861 cgaagcggga tcgtaaacgt agggctagag ggaatcatgg tcatgggtgc ttttagttcc
    19921 atcgttttca acttgacgat gagtccatca cttggttcta tgacaccatg gatcgctatt
    19981 ttagtgggtg gcgtcgtagg tatcctattt tctctgattc acgcagtagc aacagtcagt
    20041 ttgcgtgctg accatattat cagcgggaca gtaattaatc tgatggcacc tgctttaggt
    20101 gttttcttga tcaaagcatg gtatggtaaa ggtcaaactg ataacatcac gcagaatctg
    20161 gggtattttt ctttcccagg attagcagat attccggtca ttggaccaat tttctttaaa
    20221 aatacattct tacctgctta ttgtgctatt ttgattgctg tcctagcttg ggtgatcatc
    20281 ttcaagacga aattcggctt gcgcctccgt tcagttggtg aaaatcctca agctgccgac
    20341 acattaggta tcaatgtata tgctatgcgt tattcaggcg tactgatttc tggcttgtta
    20401 ggcggtatgg gcggtgctgt ttttgctcag tcgatttccg gtaacttttc agctggtacg
    20461 atcgttggac aagggttcat ctccatggct gctatgatct ttggtaagtg gaatccttta
    20521 ggggcaatgg gtgcctcatt gttctttggt tttgctcaaa gcttgagtat cattggcgca
    20581 caattaccag ttatttcttc gattccgcca gtattgctgc aaattgctcc atatttgctg
    20641 acaatcattg tgctggttgt tttcttaggg aaagcttctg gtccaaaagc aaacgggaag
    20701 aactatatca aatcaaaata atcttttagc gaataaaaag ggtgggttac gggaagtgtt
    20761 tttcgtctcg ccctttttgt tttaaaggca ataaaaataa aaagaaagaa ggaataatca
    20821 tgtttaaacg cgtacatctg atcgtcatgg attcagtagg aattggagaa gcaccagatg
    20881 ccgataagtt cggtgatgtt ggttctgata cattaggaca cattgcgaaa gaagcaggat
    20941 tgaacgttcc acatttagag cagcttggtt taggaacgat ccgtcctctt gaaggtgtgg
    21001 aatcagtgaa agatcatcaa ggctatgcga cgaaattaga agaagtttct gtagggaaag
    21061 atacgatgac aggccactgg gaaatcatgg gattgaatat caaaactcca tttcgtgtgt
    21121 ttcctaatgg attccctgat gatctgatca aacaaatcga agaattttct ggccgtaaag
    21181 tcgtatgtaa caaaccttat agcggaacag ctgttattga cgattacggt gaacaccaaa
    21241 tgaaaacagg cgatttaatt gtatatactt ctgccgatcc tgtccttcag atcgcggcac
    21301 atgaagaaat cattccttta gaagaattat atcggatttg ccaattcgtt cgtgatataa
    21361 caaaagatga tccgtatatg attggccgaa tcattgcacg tccgtacgtg ggtgaaccag
    21421 gagacttcac acgaacaagc aatcgccatg attatgcgtt gaatccattc ggacacacag
    21481 tccttgattc tttgaaagaa gcaggaaagg acgtgattgc tgttggaaag atcaacgata
    21541 ttttcaacgg acaaggaatc actgaatctg tccgcacgaa aagcaatatg gatggcgttg
    21601 accagctgct gaaagttatg aaaaacgatt tttcaggaat cagctttacc aatttagtag
    21661 attttgatgc attatacggt catcgtcggg atgtagtcgg ctatgcgcat gcgattgaag
    21721 aatttgactt acgaattcca gaattgcttg aagcgatgga agaagacgac ttgctaatga
    21781 ttacagccga tcacggaaac gatccgacgt ttactggtac cgatcatacg cgagaatatg
    21841 taccgttatt ggtttacagt aaaaaaatga aagaacaagg ggcattgcct caaggatatt
    21901 attcagatat ttcagcaacg attgctgaga actttagtgt ttcttcgact gaaaatggcg
    21961 aaagcttctt gaaattatta aaataatctt tttaaatagg agaaagcaaa tgaccaagtt
    22021 aagcgagatg ttacaagaaa cgacccagtt tatccttgat aaaggagtaa aagaaattga
    22081 ttttggtttg attctaggtt caggattagg tgaattagca gatgaaatcg aagatgctgt
    22141 aatgatttct tatgatgaga tcccgttctt tcctgtttcg acagtagttg ggcatgcagg
    22201 aaagctagtt tatgggtctc tggcaggcaa gaaagtgtta gccatgcaag ggagattcca
    22261 ctactatgaa ggtcattcca tgcaaacagt gacctatcca gtacgtgtga tggccggact
    22321 aggggcccat tcagtcattg tgactaatgc atgtggtggt gtcaacgaat catttgtacc
    22381 aggagatttg atgctgatta ccgatcatat caattttact ggtgaaaatc ctttgatcgg
    22441 tccgaatgaa gatgcaatgg gccctagatt tccagatatg agtcaagctt atacgcctga
    22501 ctatcaagca acagcaaaag cagcagcaga aaaactaggt ttggatctta aagaaggcgt
    22561 atatatgggc tattctggac caacttatga aacgcctgcg gagatccgaa tgtctcggac
    22621 aataggagcc gatgcagtag ggatgtcgac tgttccagaa gtcatcgtag cagctcacag
    22681 cggattaaaa gtgttaggaa tctcttgtat taccaactta gcagcaggta tgcaagcgaa
    22741 tctgagccat gaagaagttg tagaaacaac tcagagagtc aaacaatctt ttaaagcatt
    22801 ggttaaagaa acattgacat tattgtaata ggaggaacaa taaaatgagt gtgcatattg
    22861 aagcgaaaga aggcgagatc gccgataaga ttttacttcc gggagatcct ttgcgagcta
    22921 aatatattgc ggagactttt ttggaagatc cagtttgtta caatcaggta cgcggtatgt
    22981 taggctttac cggcaaatat aaaggagaac gtatttctgt tcaaggaaca ggaatgggaa
    23041 tgccatcagc caccatctat gcccatgaat tgatccagtc gtatggtgta aagaaattga
    23101 ttcgagtagg tacatgcggt gcattgtcaa aagacgtcca tgttcgtgat ttagtactag
    23161 cacaaggtgc agcgaccagt tcttcgatga tcgaaaaaaa tttccaagcc tttcattttc
    23221 ctccaatcag tgatttcaat ctattactga aagcatatga gatagctaaa gaaaagggct
    23281 atacggttca tgtaggaaat gttctttcgg aagattcttt ctacaaagat gatttgacag
    23341 agacgttcca attagctgaa cttggcgttt taggagtgga aatggaagca gcggctcttt
    23401 attacttagg cgcgaaatac catgtgcaga cattaagttt gatgaccgtt agcgaccatt
    23461 tgatcaccgg tgaagaaaca acagctgcag aacgtcaatc tacgttcaat gaaatgatcg
    23521 aagtaggatt ggaaacagcg atagcagaat aagaaggaaa tgaaaaagct gccctgcatt
    23581 aagtaataag aacatccaag caaaaatagc tcctcatgtt tttgacttgg ctggacttat
    23641 tattgcaaat gtaagctttt gaacaccgtt taccaagagg ttgtgaatct gccgtttaac
    23701 tctgagtcac aaggaacaat ttcaaaaa
//
LOCUS       DAJSMK010000230        20862 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.042, whole genome shotgun sequence.
ACCESSION   DAJSMK010000230 DAJSMK010000000
VERSION     DAJSMK010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.042"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            267..1304
                     /locus_tag="ON488_002760"
     CDS             267..1304
                     /locus_tag="ON488_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HCR3232859.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(1393..1716)
                     /locus_tag="ON488_002761"
     CDS             complement(1393..1716)
                     /locus_tag="ON488_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HCR3232860.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(1703..2410)
                     /locus_tag="ON488_002762"
     CDS             complement(1703..2410)
                     /locus_tag="ON488_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HCR3232861.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            2496..2837
                     /locus_tag="ON488_002763"
     CDS             2496..2837
                     /locus_tag="ON488_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HCR3232862.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(3008..3856)
                     /locus_tag="ON488_002764"
     CDS             complement(3008..3856)
                     /locus_tag="ON488_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232863.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            4454..5317
                     /locus_tag="ON488_002765"
     CDS             4454..5317
                     /locus_tag="ON488_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HCR3232864.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            5417..5899
                     /locus_tag="ON488_002766"
     CDS             5417..5899
                     /locus_tag="ON488_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCR3232865.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(6162..6629)
                     /locus_tag="ON488_002767"
     CDS             complement(6162..6629)
                     /locus_tag="ON488_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HCR3232866.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            6752..7603
                     /locus_tag="ON488_002768"
     CDS             6752..7603
                     /locus_tag="ON488_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3232867.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(7854..9812)
                     /locus_tag="ON488_002769"
     CDS             complement(7854..9812)
                     /locus_tag="ON488_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HCR3232868.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(9809..10681)
                     /locus_tag="ON488_002770"
     CDS             complement(9809..10681)
                     /locus_tag="ON488_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HCR3232869.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(11023..11895)
                     /locus_tag="ON488_002771"
     CDS             complement(11023..11895)
                     /locus_tag="ON488_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HCR3232870.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            12023..12592
                     /locus_tag="ON488_002772"
     CDS             12023..12592
                     /locus_tag="ON488_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HCR3232871.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12659..13396
                     /locus_tag="ON488_002773"
     CDS             12659..13396
                     /locus_tag="ON488_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HCR3232872.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            13627..14895
                     /locus_tag="ON488_002774"
     CDS             13627..14895
                     /locus_tag="ON488_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HCR3232873.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            15382..15846
                     /locus_tag="ON488_002775"
     CDS             15382..15846
                     /locus_tag="ON488_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HCR3232874.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            15830..16459
                     /locus_tag="ON488_002776"
     CDS             15830..16459
                     /locus_tag="ON488_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HCR3232875.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            16813..18291
                     /gene="msr(C)"
                     /locus_tag="ON488_002777"
     CDS             16813..18291
                     /gene="msr(C)"
                     /locus_tag="ON488_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HCR3232876.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            18338..18784
                     /locus_tag="ON488_002778"
     CDS             18338..18784
                     /locus_tag="ON488_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HCR3232877.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(18983..19498)
                     /locus_tag="ON488_002779"
     CDS             complement(18983..19498)
                     /locus_tag="ON488_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HCR3232878.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            19615..20816
                     /locus_tag="ON488_002780"
                     /pseudo
     CDS             19615..20816
                     /locus_tag="ON488_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         6632 a         3703 c         4314 g         6213 t
ORIGIN      
        1 caaggagcaa tttcaaaaaa cagcttctca tgtttgatga atattttgac ttgtgaccga
       61 agagttggta ggagaacacc gtttataaga ggttgtgaca aaagtcttgt cgcaacctct
      121 tttttaacca aaaaagtgca aatagtttac tttaagtaag agaataatta tgatgaataa
      181 aaaaggtgga acaaatagca tactatatat attgaaatga acactgtatg gatgctccaa
      241 cttgatgaag ctaaggagga attcgtatgt cagaaaagga attaatgaag gtagtcggtt
      301 tttatgaagg gttgccgatc gatgatccaa aaagctttat tgatgaaaaa gaacagatac
      361 ctgtacccag ttcacgggat cttctggtaa aagtcaacgc agtatctgtt aatcctgtcg
      421 atacgaaact tcgccaagat aacgggataa gaaatgcttt acgtatctta ggttttgatg
      481 gagtcgggaa agttgttgct gtaggtgacg aagtgcaaaa attttctgtc ggcgatcgcg
      541 ttttttacgc aggtacaaca acaagagcag gaagcaatca agaataccaa ctagttgacg
      601 aacgtattgt cgctcttgca ccaaaaaatc tttcagatga agaagctgca gccttgccgt
      661 tgacctcatt gaccgcttat gaattgttat ttgaaaaatt tggtctaact ccagaagaaa
      721 atgccaatcg cgggaaaaaa atcttagtga tcaacggatc cgggggcgtc ggttcgattt
      781 tgaatcaact agcgcattgg gctggcctag aagtctacgc gactgcaagt ccgaagaatt
      841 ttgaatggct gaaaaaaaca ggtgtagact atccaatcga ttatcatcac gacttaagta
      901 aaagttttcg tgaattagga atcgatcaag tagagtatgt cgctgtatta ttcgatatta
      961 cccgctactt tgatcaaatc aagcaccttg tccgaccatt tggacatgtg ggaacgatcg
     1021 tagggatcaa agagccgtta gatataggtg tttggaaaaa ccaatctatc agcttcgact
     1081 gggagtatat gttcgctaaa acagactata actatgaaat cgaaacgcaa ggagaagctt
     1141 tagcgcacat tgctgcttta gcaaatgaag ggattatccg cagtacattg agcaaggtct
     1201 attcagatgg gatgaatgcg aagaacttga aacaagcaac caaagacgta gaaacaggac
     1261 atatgttagg aaaagtcgtt gttagtggtc cgttcaacgg ataagcaaga atacgccgat
     1321 ttttttctta tttgactttg ataaaaacaa gagcgcatga cagtaatttg ccataagctc
     1381 ttgttttttt atttataata agcgaatcaa cgaaagggaa agaattcctg ccaagacgat
     1441 caccaataag ctttttgaaa gaatagcagc taaaagtgta ggaactgaag ccaaagcatt
     1501 ttcgagattg atctgcggca gatgtccgat attttgggta aatagactgc tgaaccataa
     1561 agcagacata atgacgatcg ggacaaaact taaatactca agcaacggtt gcggtaaatc
     1621 gaattttttc agtaagacaa atggtaggac cctagaaagc caagttgcta aagtacaacc
     1681 taaaatagtc agcaatgtaa actcaaaaga aggcatgttt gatccacacc cccaatccgc
     1741 acccaatcag tgttacaact acaatcacta agttgcttgg gataaaaatc agtccgacat
     1801 ataccagaat caaagtgaga ccaatcagga tcaactgtaa tcgtttagag gtgtttctat
     1861 cagaaatgac ttgaagataa agtaacccga taaacatagc gacgatggcg aaatccaaac
     1921 caaacttttt cggatcagta ataaaattcc ctaaaagtgc gccaacaaga gaagaaccca
     1981 cccacgtcaa ataagaaatc caattagctg tattcatcca acgaaagttt aacttttgtc
     2041 cagtatagtt caatttattc attcccagtg cgaaactttc atctgtcagc aatgtgccaa
     2101 tcagcagatt ttgaagcagc cgatttttct tgaaataagg agcaatcgtc atactcatca
     2161 gaatcattcg ggaattgact agaaaggtcg agaaaacgat ggaaagcaat gggctgtgac
     2221 tagcaagcat gctgactgtg ataaattggg cagaaccagc atagaccagc agggacatca
     2281 acgtgacgac tagtggatga aatccggcag ctttcccaac gataccaaat gcaagtccaa
     2341 taccgatata accgaaaacg gtaggtaacg tgtctttgat cgcagttttt atatctaact
     2401 tttcatccaa taacaaaact cctttagcac gacataaatt ttcataattg tcgttaaact
     2461 tgtgaatatt ctaaattttt aatgagcatt tgtcaatggt gggattgaaa cgtaaagaac
     2521 tagcgggtcg cagatttaca cgtattgttt cggtgggagg aggcgcgaaa aatcttgcat
     2581 ggctacaaat ccaagctgat attttcgatg caacggtcta ttgtttaagt atggaggaag
     2641 gacctgcatt aggcgcaaca atgattgctg cactagggtt agggtggttc gacacacctg
     2701 aaagttgttg tcagaatttt atccaatata cagatgcagc ggaacctctc ttacaaaatg
     2761 tagaaaagta tcataaaatc tatcaacaat gccggaaaat ctatccagca acgaaggaaa
     2821 tttgtcatga cttataaaac aaaacgcgta cctaatagtc aaatgactaa tattgggtac
     2881 gcgttaagtc ttctttactt catcctttgc atgattcgtg tttttaaagc aaggtctgct
     2941 gtatttcttg tggatttagg atggttgtta tcgtttactt gctatttttc attgaaatcg
     3001 tctttcttta ccgtttcttt agttttttat ctattttttt cttttggtta gaaaattctt
     3061 tttcccgaaa gtcttctttc aggattttta tagagtagcg ttttgaataa gaggcgtcag
     3121 tatgatcgac ttggcagacg aaccaagaga acatttgcct tttttctgca tgaggtgctt
     3181 ctgctaataa ttctttccat aaataataac agtcctctat cagaagaagg gttcgttcat
     3241 cctcaggctc ccaatagaat gtttcgagag tagcaatcac ttcattgatc aattcgaatg
     3301 cgggaagata ggcattttgc tgaataagcg attcaactgc ttcttggatg aactttcgca
     3361 tctccatgat gaacttcgct gttttcctgt ttttgttttt cttgataata tgatcgtatt
     3421 tatggatgat agttgttaat ttatctgaat aatttattgc atgaaatggc atcttaactt
     3481 tgaagcgttc gataaagtgc ggatgttcta taagaatctc tgttaaaagc tcccgtacaa
     3541 gagaggaact agcggaggaa acaagggacg agagttcgga aagtgagtag ttggattttt
     3601 ttattggacg ttcttcgtaa gcgaataaga cagcagccat gtgtttgcat ttttttcctt
     3661 ctatggcata tagacaatca caagtcatgt tggtcttttc atcccaagtg atcactacct
     3721 tataatcttc cgtgccagaa actgttgcgg acaagtactt gcttgtatag ttcaaatgac
     3781 ggacaaaacc gtgcagatga tagctgtaac cgcgttccaa aacgttttca ggaaaatact
     3841 caagccaatt attcatctag ttctcctttc atgaaacact tatttatatt tagtataaag
     3901 aaacgtttaa gaaaaaagta gctgatttta catatttgat aatcactttt gctcgaattg
     3961 tcaaaaattc attctccttt tcttttctta gagaatgtga gaaaaagtaa aagaatagcg
     4021 tgttttaaag atggaacttt ttttgttttt tatttatctg acaaaaatga agtgattttg
     4081 ttagaaataa ataattgttc caattgataa aagaggtatg atgtatcgca aagaaaaatc
     4141 caagcagcgt tctgatcagc agtttgaaca acaatttgct ttgtacagta ggtagtaagc
     4201 ggattaacta agggaataaa agatattttt accgctttgt ttacttagaa tctgtcttcc
     4261 ccaaaattta tttttctaaa ggtaaaacat agataggcag ataataccaa ttatccgtta
     4321 cgaaacgctg cttgagaatt ttctttagat ccatacaaca ttttctacat ctgactaaat
     4381 tggttcctga ttcatcaagt aattgacttt ctttgataat atgataaaaa ggcaatcaag
     4441 gaggaagata aatatgctta aagatctgaa ccaattgatc gattacatcg aagaacattt
     4501 gacagaagga ctttcctata aaataatagc cgaaaataca ggaatctctg aatatcaatt
     4561 aaaacgcatc tttacgttta ttgcagggat gtcgctaatg gactatatca aaaaccgtag
     4621 attggctttg gctaatcgcg atcttctaga tggatcaaga gtgacagaaa cggcgtttag
     4681 atatggatat gaaacagtcg aaggtttttc aagagctttt cgtgattggt caggatatct
     4741 gccttcagaa atcagtagat acggcataca aaaatctttt ccacgcttga cattttttat
     4801 tgatgtcaga ggaggaaaat cgatggaatt tcgtatcgaa aagaaagaac agttttatgt
     4861 ggcaggtgtg gcgaaaaaag ttcctgtcaa atttgaagga gtcaatcaag aaatacaaaa
     4921 gttagcgcag acgatcacgg agactcaaag ggaagagatg cataagttag gagatttata
     4981 tccaaatcaa gtaatcaacg tttcttatgg atttgatgga gaccgcttgg aagaaaaggg
     5041 cagtttgatg cacatgattg gctttgctac gacaaaagaa aatccgtacg ctgatttaga
     5101 aatgcttgct atagaagaac acacttgggc catttttcct aataaagggc catttcccca
     5161 aactttacaa gatacttggg ggaaaatcta tgcagaatgg cttccttctt cagattatgg
     5221 gttagtcgaa gctcccgaga tctcttttac aaaatgggga gaggatttca gtaatgttta
     5281 cagtgagatt tggattgcag tgaaagcaaa aaaatagtta aaaaataaaa atatccctag
     5341 aaaaaagagc gtaatcgtgt catttccctt taattttatg taagatgaac ttaatataat
     5401 agaaagggtg ggagaaatgg caaagtatag gatcgaagaa aaaccagatt ttacggtgac
     5461 gggtattggt gtggaattga agagtagcaa tacggatttt gtcggtttgg ctgcagagaa
     5521 acaagcattt gagcaaaaag ttatcggtaa tggaacaata gatgcattga aacaagctgc
     5581 tgaaaatcat tatttcttta cagtcaacga accctataac gggaaaatga tgtactatgt
     5641 cggtgttcaa acgagtcagg atgttccaaa cactacgcga atcatcccat tcccaaaagg
     5701 aacgtatctt gttgtaagcg ctttagcaga atcgcctgaa gaattaagaa atgatttgac
     5761 gaatacggcc tttgggcatg ttttaagaga agtagaagat tacgcctatg ttgggggtcc
     5821 aaatgctgta gtcgaaatgg gagttaccaa cgggaaatat atgggagaaa tctggatacc
     5881 ggtagtcaat aaaccatgat aatatagagg tcgtgaaagt agcgctttga cctgagcatt
     5941 agagaggaaa aatgggaaat agctttccat attttgcatt tttcagaact aatgccgagg
     6001 gtcagctact tgaacaccgt ttatcaagac gtcatgactt cagcgctttg acctgagcat
     6061 tagagaggaa aaaggggcat gacaaggctt ttgtcccccg gagaataaaa gaatttatgt
     6121 agacgattcc gatcagaaaa atgcaggcac agtagagaga attataaaaa tctctctacg
     6181 aggcctgtgt tttctggtct tttttctttt tccaaaacgg ctattttatg tatcagacta
     6241 tcaagtgtga tcttagccat ttcttcttct gcctttttct gcagccgagc gtagctttct
     6301 tctaaagctt cttggatatt cgcaccaacg acgcaatttg gatttgtttt tggatcgact
     6361 tggataagct gtgtattacc ttcgatgctg cgatagacat ctagtaaaga aatctgatct
     6421 ggacttttgg caagggaagg ctgcggtttt ccggtttttg taaagatcaa accggatttt
     6481 ttgagctgac tcatgatttt acgtacattt gctgcatttg tttcgatact actggcaatc
     6541 atctcactag aaagtgatcg ggtatcttga aacatttcaa tataggcaag tacatggatt
     6601 gcatcactaa attgcagaga atacttcatc agttgtcatc ctttcatttt ttttgcttga
     6661 cttatcttac cacactcttt atgataaagg tgtaatttat aaatgtacag ctgtaaatct
     6721 taacaaataa aaagaatagg gagtggcaaa tatgcattat ttagtaacag gagcaactgg
     6781 aggttttggt ggttatgcgc tggaattctt aaaaaagatg gttccacaaa atgaaatcta
     6841 tgtactagta cgtagtgaag aaaaaggaga agcactgaaa gaagctggat ttaatatacg
     6901 tattggtgat tatgatgatt tagactcaat gaaagaagcg ttgaaaggaa tagatcgatt
     6961 gctttttgtc tctggcgttc caggaaatcg tcaagccgaa cataagaatg tagtgaaggc
     7021 agcacaagca gctggggtat cttatatcgc ttatacaagt tttgcagatg ccgatcactc
     7081 gatcagtgta ttagcgccag atcaccaatt cactgaaaaa atgattaagg attcaggtat
     7141 ttcccataca tttttacgga ataattggta tgtagagaat gaattaccta tcattgggca
     7201 ggctttaaaa actggtcaat tcgtttatgc tgcaggaaat ggaaaaacag gttgggcatt
     7261 gaaacgtgaa tatgcagaag ctgcagcaaa agtactagta gaaagtgact ctccagaaat
     7321 cttagaatta tccggcaatc taactgacta tgaagaatta gccaaggcat tagagcgtgc
     7381 gacaggtaaa gagttagaaa ttattgaagc aagtgatgca gcgtttgtcg aaaatctaaa
     7441 agaagccgga ttccctcaag aagcagctga catgttttta gcgatccaac atgatattaa
     7501 aaaggatcag ttagctattt cctctgatga tttagaaaaa gtattgggaa aaccattaac
     7561 ttctcttgaa gcagcattaa aagaaatatt ggatcaggaa taatgtataa agaggttgtg
     7621 aaaaagccga ttagttttga gtatgaagaa aaattttgtg aaaaagctgt tctgcatcaa
     7681 gtaataagaa gagtcaaata aaaaatagct cttcatatgt ttcgtttagc tggacttatt
     7741 accgcggagt tggcaggaga acgccgtttt tattcggaaa aaggagctga gacaagattt
     7801 ttgtctcagc tcctgtttgt ttatcgataa aaaagtctgg ggaagacgat ggctcaggct
     7861 ttgttggaaa cagagccgat tttatcattt gcttttacat cacgtgcggg ttcgatttct
     7921 aagctttgga ctttgtcgcc atttgtgaat acaacgacca tatccgtgtt tttgcctgca
     7981 gattgaatag cggcaagatc aactaaagca atcaattgac ctcttgcgac tttttgacct
     8041 tcttctacat ataaagtgaa tggttcgcct tttaagtcaa cagtgttgat gcccatatga
     8101 agcaagactt cgataccagc atctgtttgg attccgacag catgtttcgt tgggaaaatg
     8161 tttgtgatcg taccagcgat tggagagaag atttctccat tttctggtaa tacagcatag
     8221 ccgtcaccca tcattttttc cgcgaataca tcatctgaaa cttcagtgat tggaatcagt
     8281 ttcccatttg cgatagcgta aatatcttgt tcgatcgttt caccggcaaa tgtttctgtt
     8341 ttaaccacgg tgtttgtttg tgcaggtcgt gctgcagcac caccatgtag ttttgccatc
     8401 tcatctgcaa cgaattgtac ttctgtacct acgatgactt gcgcattttt tccgtcgatg
     8461 atcttcatac caggtacgcc agtggctttg attttatttt gatcgatcag gcctgtatct
     8521 ttgacttgca aacgaaggcg tgtagtacag ttatcgatcg aagttacatt gtcggctccg
     8581 cctaatgcag cgtagatttt gcttgcttgt gccgcatatt tattgtctga attagtcgtt
     8641 gcagtatcgt catctgaaag atctgcttcc tcgcggccag gagtcatcag atggaatttt
     8701 ttgatagcaa agttaaagcc aaagtagtaa atcactgctg ttactaatcc ttggacgatc
     8761 aacatcaatg gctgattcgc aatcggattt ttcaaagata ggaagtaatc gacaaatccg
     8821 gcactaaagg caaatcctgc tgtccaatgg aagaatgcac tcactgctaa agaaatccca
     8881 gtgaaaattg catgcaagac atataatggc caagcaacga acataaatga aaattcaagt
     8941 ggttctgtca caccagtaaa gaatgaagca aaagctgctg ctagcatcaa ggaagctgtt
     9001 tttgctttgt tttctggacg tgcatttctg taaatagcat atgctcctgc tggaagcccg
     9061 aacatcatga ttgggaaaaa tccagcttga tacattcctg ttacgccttt tgttccttca
     9121 gaagccaaaa atttaccaat atcattgatt cctgctacgt caaaccagaa cacggagttc
     9181 attgcttgat gcaatcctgt agggatcagt aaacggttga agaagccata aagacctgca
     9241 ccaccccagc ctaaactcaa aatgaattta gcaaaagaaa ctaaagcaga gtaaaccgga
     9301 ggccatacga gcagtagcac tgcactgatc agcaacatga caaaggcagc caagattggc
     9361 actagacgct tgccgctaaa gaaagataaa gccatcggta attttgcttc gtggaaacga
     9421 ttataaagag ctgccgcaat caatccggca ataataccaa taaatacgtt actgatctga
     9481 gcaaaagatg gatcaactga ttctggtttg atattcaata aagtagctac tgaatcagtt
     9541 tttaaaacat ttactggaac ttcaaatgcg accaaacctg ccaaggcagc agcacctgat
     9601 ttgtccactg acatccctag tgctaaccca acggcaaaca gcaaaggtaa ttgacctaaa
     9661 actgcgttac cgccagcttg taaaaaatga gcgacaatgt cgttactata agatgcccac
     9721 cagtttccga tccctactag taaagcagca gcaggtaaga ccgcaactgg aagttgaagg
     9781 gaacgtccca ttcgttgtag atatgctttc aatttttttc ctcctcatga ttgttaacat
     9841 ttgtttgtac gattgcgctt cttaaacgct cgatatggat ggccaagtaa cccagttctt
     9901 ctttcgtgat cgcgagctgg tattctttgg tcagcaacac acggattttt ttagaaatct
     9961 tatagctttc tgggtatttt cgtttgacca tttctacgat ttccgtgtct aaaacagcat
    10021 attgttgcgc atgggttcgt tgtagaagca gtcgtaaatg attcaccagt cttgaataat
    10081 tcagtgaaaa tggttctgaa tggatatctg tttccaattc tgattccact aaatggatga
    10141 tgtcagatac aatcgtcact tcacggatac tgcgatggtt attgttccga ccgcttcgtc
    10201 cgctgtgaat atggattgcg atatatcctg cttcgtcata agtatatgga atcccaagct
    10261 cttttgtcag atactctact gcccattgag caatactgaa ttcatcactg taaagcactt
    10321 cgatttctct taaaagtttg ttgcggatga cgataccgtt attaatgttc tccgcagaaa
    10381 aagcaatgtg gtcggtcaaa gcgatcaata catgttcatt caacttttcc atcaaaacag
    10441 tttccgcatg atcaatgatc gtttctgctg caaataaaaa gcgttcatca atctgattaa
    10501 gtaaattttg caacttgatt tgaccttctg gttccatgac aaatatccgt tcgacatcac
    10561 gatcaaaaat caaatcattt ctttttctgt caaatccaat cccttttcca atagctactt
    10621 tttcctgtcc accgtcatct accaatactg cattttgatt aaagatcttt ttgattttca
    10681 tgcgcgcacc ctttttgaag atttggtttt cacgtttgct agaccagttg attgcggcca
    10741 aacaaaaata gacacgaaaa acctcctagg gaaaccatgt tcctcagaga tttttcatgc
    10801 ctagtatgat ctagtcacat gaaacgaatt attgttaacg taatcaattt tatatagaca
    10861 gttatgtttt gtcaattctt tttttataat tatagtaatt tactggaatt atcagaaata
    10921 aaaggaagaa ataaattaag aaacttatgt tatttaatcg ttggatcttt tgcttatctt
    10981 attcgttgtt aaaaagctga aagcgaagga aaaaaactct acttaactgt atttctccgt
    11041 taggacatct aaaaatttac gagcagcagg agaaagaggc tggtcttttt tccaaatgag
    11101 attcagtgaa gcttgtaatg gcggatcgag tgggatgaat attttttccg tcccataagt
    11161 attgatgatc ccatctagag ctaatgcacc aaaagtcccg ttatcgacca tcaaagaagc
    11221 attgtacaat aagttatatg ttccgacgat cgataactga tctatgctga aacctagcca
    11281 ttcagctagt tgactgtcca ctgacgtttg ccgggaaatg atcaaaggaa cagttttcag
    11341 ttcctgcgga tggatgacgg tttgctttgc taaaggatga tttcgatgta tcaaaagtcc
    11401 ccaacgatct tgggctggca gtcgaaatga ctggtatttt tgtttgtttg tcggttcgat
    11461 tacgagtcca aaatcaagta atccgctatc cagtttgtct atgatatcat ctgcattccc
    11521 gctatataaa tgaaactgga tatcaggatg cgccttgatc aacgaatgaa ggctatcaga
    11581 aatgaaagag attgctttag tttcgcctcc gccaatgtag atttctccag agatgattgc
    11641 gtcatttgtt aaattgttcg ccgttttttc taccaacgac aagatttctt ttccttttga
    11701 ataaagatat cgaccagaat ccgtcaactg tatctctcgg gagccccgag tgaaaagtgt
    11761 cacaccaagt tcttcttcta aatctttcag ttgttttgag agagtaggtt gcgtgatatg
    11821 cagagatttt gctgctcggc tgatattttt ttctctagct actgctaaaa aatacgtcag
    11881 tatacgaata tccatttttt ccctcctgtt tttaaaaaag cataccacta agtatagtta
    11941 aaaggaatag ttaagtatgt tttataagta ttagacatga taagccgtcc gttataaagt
    12001 aaggataaaa ggagggagca aaatgacaag cctcatcgaa aaacaaatcg tcaataaaga
    12061 gattcgagta acggatccgc tctttgaagt gatccatcag atccaagctg aaaacgaaga
    12121 gcctttagca gcgctgaata ctgggtacca tgaaccagca gatatccgca aacggctaga
    12181 aaatatcatt agtgacaaag tagatgatac ggtgactgtt ctgctgcctt tttatacaga
    12241 tttcggcaaa catattagta tagggaaaaa tgtctttatc aatcgtcaag tgatgttcgt
    12301 tgacttaggt ggcatctgtt tagaagattc agtattgatt ggtcctcgtg tcaacctcat
    12361 cacggtgaac catctaaccg atccaaaaga acgaagaggc ttgtcagtaa agccaatcca
    12421 catcaagaaa aatgcttgga tcggagcagg agcaactatt ctgccaggcg taacgattgg
    12481 cgagaatgcc attgttgcag cgaatgcaac tgttacgaaa gatgtcccag acaataccat
    12541 cgttgcagga atccctgcca aaatcgtcaa acctgtcgaa cggattattt gaacagtaag
    12601 atgaaataag agatagtgag tataagcaag agatttttca aaacaggagg agaatagaat
    12661 gaatgattta tcagaaaaag tgattgtcat catgggcgct tcaagcggaa tcggtgaagc
    12721 aacaacgaag ctattagcag aaaaaggggc taaactagtt atagctgcac gccgagaaga
    12781 tcgcctaaaa gcaataaaag aatctttacc agaagctgag ctatatattc aaacagcaga
    12841 tgtaagagat tttgcacaag tccaagcagt tatcgattta gcgatggaaa agttcggtcg
    12901 aatcgatgta ttgtacaata atgcaggaat catgccaacc gctccattag ttgaaggtca
    12961 ccgtgatgaa tggcaaaata tgcttgatat caacatcatg ggtgtgttaa atggaatttc
    13021 cgccgtactt ccaatcatgg aaaaacaaaa atctgggcat atcatttcaa ctgattctgt
    13081 ggcgggacat gttgtttatc ctgattccgc cgtttattgc ggaacaaaat ttgctgtccg
    13141 tgcaatcatg gaaggattac gtcaagagca acggcaaaat aacatcaaat ctacgatcat
    13201 ctctccagga gctgttcaaa ctgaattata tcaaaccatc agcgacaaaa aggctgctct
    13261 tgaacttcat gaagcgcaaa aagaatgggg attgacctcc gaagatatag cttctgctgt
    13321 agcatttgcg atagaaacgc cagaccggat gtctgtcagt aacatgatta tccgtccgac
    13381 gacacaggaa gtataatcca taacggataa tatccaaaga gaattacttg ttaaatagtt
    13441 attcaaacga ccatcaattt aaggcgtgaa tggagaagaa tattcttcat ttacgtcttt
    13501 ttatgtagaa aaagcaaatt tatcaaaaag aaacaaatgt tatttaaata tggacattga
    13561 cttgctttta cttttttagt tacactgtta tttaggaaaa gtttcataat tcaaaggaga
    13621 aaaaagatga aagcaaagaa tttattattt agcgttattc ttttaggaaa tctagcagtt
    13681 gccaacacaa cagtgctagc tgaagaatcg acagaaactg tcgcaactca gacatcgagt
    13741 tcttcagaaa caggaattga aaacgataca gagagtactt tgcagtcagc tactgtctca
    13801 gaaaatacaa tttcaaccga agaaccaaca actgaaacaa cagaacaaac acaaaccgaa
    13861 gacagtacat cagcagaagc tcagaacaat ccagagaatg cagaagaaat cacgaaccaa
    13921 ttgacagatg ggcaaacatt gacacatacc catcaagcag atttgtctga attcgaaaac
    13981 tatactggct atgcttttta tgctcgctca tctgctaatt ctcaacaagc gttcattgat
    14041 agtattgcct caactgcaca aagtttggca agtgccaatg acttatatgc atcagtcatg
    14101 attgctcaag ccatcgttga aagtggctgg gggaacagta ctttggcttc tgcccctaat
    14161 tacaatctat ttgggattaa aggaagctat aatggccaat ctgttacgat gcctacttcg
    14221 gaatatgtga atgggcaatg gattacggtg aatgccgctt ttagaaaata tccttcgtac
    14281 aaagaatcat tgcaagataa cgtaacggta ttgaaaacga cttcttttca gccaggcgtt
    14341 tactactatt ccggtgcatg gaaaagcaat acgaactctt acaaagatgc tacggcttgg
    14401 ctaacaggtc gttatgccac tgcgcctaat tatggttcta cattgaacaa tgtaatcgaa
    14461 acctataatc tgacacagta tgatacagca ccaacttcaa cttctccgat gtatcgtctg
    14521 tataaccgtc atacaggaga acatttatat acattgaatg ccggagaaaa aaattatctg
    14581 ccaactgtag gctgggaata tgaagggatt gcttggcaag caccaaacag cggacaacct
    14641 gtctaccgtt tatacaatcc ttacagtgga gaccatcatt acacaatggc acaatctgag
    14701 atcaactctt taacaaaaat cggttggcgt tatgaaggtc taagttttta ttctggtggt
    14761 tccaagccaa tttatcgact atttaatcca aatgaaaaaa ctggtaccca tcactatacc
    14821 ttgagtgcta aggaaagaga ttggctaaca ccgatgggct ggagatatga aggaatagga
    14881 ttttatggtt attaaaaaga ggtagtgaaa aagctgccct gcatcaagta gtaagaacag
    14941 ccaaacaaaa acagattttc atgttttttg tttggttgaa cttattaccg cagatgcaag
    15001 tttttgaaca ccgtttactc aaaaaaggtt gtgacaacat cttgtcataa cttttttatt
    15061 actgtttaag catactgatc caatttctaa tattcgacgg gattcttgca aaaggcgatt
    15121 tcggaaattt ttggcggtgt aaaattttct actgcagaag agctatcttc tatagtttga
    15181 taagaatcaa taatcttggt tttagcgttg tgctttcttt atcatttttt ccgttcattc
    15241 tacaaaaaat ttcttttctc tatacttttc tattgagagc gtttttttta ttacacagct
    15301 gattctttga cttttttctt tttttattct attattgaca agtcaatcgt tgacgagtca
    15361 attattagaa aggaggaaat tatgtcttta gaagagatta gtcacctttt atatcaaatc
    15421 aaattagccg atcaaaaaat cgtccagatc tttgaagaaa atatcggtat aagtcttact
    15481 agatacgaga tcatgatgag actgaaagaa gaaaatccat tgctacaaag cagtttgcaa
    15541 gaaaagttgc agattgatca aggagcagtt actcgtcatc tgaaggtatt ggaagcaaat
    15601 ggctatgttt cgcgtcagag aaatcctcag aacaaccggg aagtgtatgt agcgctaaca
    15661 gaaaaagccc agaagaaaat cgagcattgt gaaatggacc ataaagatac aggttccgtg
    15721 ctatccccgg ctttcagcga tgtagaaatg aaacaatttc taacactttt agataaattg
    15781 aatacccaac tttgcaatat aacaacagaa acgaaagagg ttaataataa tggaacaaaa
    15841 aaatgatttt tcaacaatta tgactggtag aagatccgtt cgcgtatatg atgaaacata
    15901 caaaatccca cacgaagaaa tgctggaaat gatcaaagaa gcgacgactg caccttcttc
    15961 tgtcaatatg caaccatggc gctttgtggt cgctgaaagc gaggaagcaa aagaaatctt
    16021 gcgtcctttg atccgtttca atacgagaca aaatgatact tcttctgcaa tggtcatgat
    16081 ttttggcgat atgcaatgtt acgaatatgg cgaagaaatc tataaccaag cttacgaatc
    16141 agggaagatg ccaaaagaag tcagagatca acaattagct gcgatcattc cttattacaa
    16201 gagtttttca agagaagaaa tgaacgatgt agtcaaagtc gattctagct tagcggctat
    16261 gcaattcatg ttagttgcgc gtgatcatgg ctatgaaaca aatccaattg gtggattcga
    16321 agcagatcag ttggcagagg catttggttt ggataaagac cgttatgttc cagttattat
    16381 tttatcaata ggaaaagcgg tagaagaagg ttacgagtct gttcgtttag caccagaaaa
    16441 gatcactacg ttcgaataaa aggttttcag ttactattca gtagctattg ctttttttga
    16501 atcgtgtgtg gtaacctaat aaaaaaggag gtcggaaaaa tgactgcatc gatgaaatta
    16561 cgtttcgaac ttttgaataa caactaaata aattcaaaag acatgtataa acaacaattt
    16621 catggatgga gtatgtccat tttttcgaac gacagtagaa taggtgaaag ctatgacaga
    16681 tttggtgatt tagtcatagt tatttcgttc agagtaggaa aagatgtgat gcagtttttt
    16741 tgcaaacaga tttttctgct cttttttagt atcgataatt gttgttttac atgaaatagg
    16801 agtgtaaaac atatggaaaa tttagcagta aatataacaa atctacaagt cagctttggc
    16861 aaccagctag aactatctat tgattctctt cgtgtctatc agcaagatcg tatagggatc
    16921 ataggagaaa atggtgtcgg taaatcgact ttgctcaaac taatagccgg tgaacttttt
    16981 cccgatcatg ggaaaatcca aacagagatc accttcaact acctgcctca attaacctat
    17041 ctcgctgaag caaaggacct aaatttggaa ttagccagtc atttccagtt aagactggaa
    17101 gaaacttcag agcggaaatg gagcggaggg gaagaacgaa agatcgagtt gatacgtctt
    17161 ctttcttctt atgaacaagg gatgcttcta gacgagccaa caacccatct agatagaaaa
    17221 agtattgatc gactgattga agagcttcgt tattattatg gtacgctggt ttttgttagt
    17281 catgatcgct attttctaga tgagctagca tcgaaaatct gggaagtaaa agacggagaa
    17341 atccgagagt tttcggggaa ttatagtgcc tatctcactc aaaaggaatt ggagaaaaag
    17401 actcagctac gagaagcaga gtcgatcatg aaagagaaaa aacgattgga aaaatcgatc
    17461 caagaaaaga aaaaacaagc ggaaaagttg gaaaaagtgt ccagtaaaaa gaaaaagcaa
    17521 caaatcagac cggatcggtt gtcttcctct aaacaaaaag acagtgtaca aaaagccatc
    17581 caaaagaatg cgaaaacatt agagagaaga ctccaaaaaa taggagaaac aaccaagccg
    17641 cagcagatga aacaaatccg ttttccagta ccaaaatctc ttgaactcca cagccgctat
    17701 cccatcatgg gacaaaatgt ccaattggaa agaagtggga gaacattact ggtaaatggt
    17761 gattttcagt tttctttagg taaaaaaatc gcgattgtcg gtgaaaatgg ttcaggtaag
    17821 acaaccttat tagaacatat ccgcaaacaa ggagaaggaa tccttctctc tccgaaagta
    17881 agctttcaag tatatcagca aaagggttat caaatgacat ctgaagaatc catcattcgt
    17941 tttgtcatga gacaaacaga gttttcagaa tcgcttgtcc gtagtttgct gaatcactta
    18001 gggtttgctc aggaaacttt gacgaaaccg ttatgtacat taagtggggg agaagcgacc
    18061 cgtctgacga ttgctttgct ttttactaag ccaagtaatg tgttgctgtt agatgaaccg
    18121 actaatttta ttgatatggc aacgatcgaa gctttagaga agctaatgca aatatatccg
    18181 ggaacgattt tgtttacttc tcatgattct tactttgtcg agcgtacggc tgatgaagtt
    18241 tatgaaataa aagggcagaa aataaaaaaa gtacttacga gaaattttta aatgtgctac
    18301 gatgattttc gtgacaaatt taaaggagtg gtacagattg cctacaaata aaaaagaagg
    18361 aataattttt acaacaatga tgtgtttttt gatggtcttg gggatgagcg cgtataattt
    18421 atggctgcat caagatcttc atttatcaag tttgttgatt ggtctagtgc ctggattcgt
    18481 ggtggctttc attttggatg tcttcatcat cggtgtgctg gcgaaaaaaa ttgcctttaa
    18541 actaccagta aatccagaaa gcaaggtcca aatgatctta actatttcat gcttgatggt
    18601 tttaggaatg gtgacatgta tgtctttatt cggtgtgatc atggaacaag gaatacctga
    18661 tcaattattc tctgcttata tgaatgcttg gaaaatgaat gtgattgccg ctttaccgtt
    18721 gcagttgatc atcgttggcc cgctttcaag aagtgtgcta aaagcaattc aaagtaatga
    18781 atgatggaac actgttattt gaaaaaaggc cttggcatgc tttttgtcat agtctcttga
    18841 atgcagttct agaaaaatag tgatccgaac gataggtttt ggcctgtcgt tcggatcgct
    18901 ttttcttttc caactgtatt gctcttttat tgaagataat ttgctcttca atagatattt
    18961 ctagaaaggt tctgtttatc ccttactcaa aaaactgctg catttgttct cttacttgct
    19021 gacaccattg gagttcctgc tgacaaagca taattctgcg ctggatcaca acataacgtc
    19081 caaattcttg tttcttgtct agcgagaggt cattcaattt tttttgattt ttttgcatga
    19141 ttttgttcag ctgttgttct ctagtgaata gcagtccagt agctgttgtt ttatcgagcg
    19201 tcgaaaaagc atagattttt gctagaaatt catctttttg cgtaggagcg ggagtttcct
    19261 ctttgatcca ttcctctaca agagcacgtc cttcatcagt caagtggtag atcttttttt
    19321 gagagtgctc gtctttgtcc aaaacggtca cataaccctg ctggtctaac ttggcaagcg
    19381 ttgtatagat ctgactgtga tgggcttccc aaaaaattgt gatcagctgc ttcaattcat
    19441 acccagaacg tggtttggat aaaagcacgc ataataatat ataggctaaa gtattcataa
    19501 aaatcctacc tctcgtctta ttttctttat tatatcacag taaagtttcc acgttttaca
    19561 tgtgcatatt tacatgtaaa ataaatcatg tatgatgcta atagagagaa agggatggaa
    19621 atattggaga atcaaataga tatacaagaa caaacaaatg aagaaacaaa ggggaaaagt
    19681 tcagcgctag ttgtagcagc tacctgtatg atcgctttta tgggagtggg tctagtagac
    19741 ccaatcttaa aaacgattgc tgcacagtta aacgctacgc cagctgaaac gaccctgtta
    19801 tttactagtt acatgttagt cactggtgtg gtgatgctat ttacaggttt cttatctagt
    19861 cggatcggtt tgaaaaaaca ttgatgacag gattgtttat catcgttgta ttcgctggtc
    19921 ttggcggatt atctgggaat atcggaatgc tgattgggtt acgtgccggc tggggtgtcg
    19981 ggaatgcttt atttgtctct actgctttag caacgatcgt cagtatttta gttggtaaca
    20041 cagaaaaagc aatcatgatg tatgaagcag cacttggctg cggaatggct gttggccctc
    20101 tagtcggtgg ggtcttgggc agtggttcat ggcgttatcc attttttggg gtagcatttt
    20161 tgatgttttg cggttttata gccctagcgg tacttttacc tgaaactgag aaaccaaaga
    20221 gaaaagtagg cctttgggaa ggtgtcaaag cgttaagcaa tcataaactt cgttcagttg
    20281 gactaatcgc attgttatat aatttcggat tctttacttt acttgcgtat gcgccatttt
    20341 tattgattgg ctattctgaa ttagaagtcg gttttgtatt ttttggctgg ggtgtgcttc
    20401 tggctattgc ttcgattttc gttgcaccgg ctcttgagcg gaagtttacg acttatcgga
    20461 caattttagc agcatttgtc ttattcatta tttgtttgct gttattagga gctggaactt
    20521 ctatgccagt ccttgtaccg atcagcattg tgttagcagg atttttccaa ggaattatca
    20581 atacactgtt gacgacgatt gctatggaaa taccaggtct gcaacgaaac gttgcttcgt
    20641 ccagctatag ttttgtccgc tttttcggtg gagctttagc accatttatt gcaggtgtga
    20701 ttggtgaaca tattggtgaa agctatgcgt tttattttgc aggtgccatt gttcttatca
    20761 gtgtatgttg tatcatttat caccgtaatt attttgctac aaatgaagaa gaataagaaa
    20821 tcagaggttg tgaaaaagct gtcctgcatc aagtcataag aa
//
LOCUS       DAJSMK010000231        14398 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.061, whole genome shotgun sequence.
ACCESSION   DAJSMK010000231 DAJSMK010000000
VERSION     DAJSMK010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.061"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(134..577)
                     /locus_tag="ON488_002781"
     CDS             complement(134..577)
                     /locus_tag="ON488_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HCR3232879.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="ON488_002782"
     CDS             complement(795..2135)
                     /locus_tag="ON488_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3232880.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="ON488_002783"
     CDS             2404..3300
                     /locus_tag="ON488_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HCR3232881.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="ON488_002784"
     CDS             complement(3450..4391)
                     /locus_tag="ON488_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HCR3232882.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="ON488_002785"
     CDS             4517..5638
                     /locus_tag="ON488_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HCR3232883.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="ON488_002786"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="ON488_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HCR3232884.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="ON488_002787"
     CDS             7426..7992
                     /locus_tag="ON488_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HCR3232885.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="ON488_002788"
     CDS             8203..9264
                     /locus_tag="ON488_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HCR3232886.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="ON488_002789"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="ON488_002789"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HCR3232887.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="ON488_002790"
     CDS             10177..12159
                     /locus_tag="ON488_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HCR3232888.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDFAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ON488_002791"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="ON488_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HCR3232889.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="ON488_002792"
     CDS             12881..14305
                     /locus_tag="ON488_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HCR3232890.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
BASE COUNT         4647 a         2598 c         3031 g         4122 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgattttgc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacgg ctctttgtca aatgatgttg gtaaagagaa atcttaga
//
LOCUS       DAJSMK010000232         9752 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.090, whole genome shotgun sequence.
ACCESSION   DAJSMK010000232 DAJSMK010000000
VERSION     DAJSMK010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.090"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            complement(565..792)
                     /locus_tag="ON488_002793"
     CDS             complement(565..792)
                     /locus_tag="ON488_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232891.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            complement(801..1274)
                     /locus_tag="ON488_002794"
     CDS             complement(801..1274)
                     /locus_tag="ON488_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HCR3232892.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            complement(1914..2087)
                     /locus_tag="ON488_002795"
     CDS             complement(1914..2087)
                     /locus_tag="ON488_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HCR3232893.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2504..3070
                     /gene="amaP"
                     /locus_tag="ON488_002796"
     CDS             2504..3070
                     /gene="amaP"
                     /locus_tag="ON488_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HCR3232894.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            3083..3271
                     /locus_tag="ON488_002797"
     CDS             3083..3271
                     /locus_tag="ON488_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HCR3232895.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            3284..3841
                     /locus_tag="ON488_002798"
     CDS             3284..3841
                     /locus_tag="ON488_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HCR3232896.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            3873..4115
                     /locus_tag="ON488_002799"
     CDS             3873..4115
                     /locus_tag="ON488_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HCR3232897.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            4456..5669
                     /locus_tag="ON488_002800"
                     /pseudo
     CDS             4456..5669
                     /locus_tag="ON488_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
     gene            5700..5918
                     /locus_tag="ON488_002801"
                     /pseudo
     CDS             5700..5918
                     /locus_tag="ON488_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6337..6810
                     /gene="dfrF"
                     /locus_tag="ON488_002802"
     CDS             6337..6810
                     /gene="dfrF"
                     /locus_tag="ON488_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HCR3232898.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            6937..7593
                     /locus_tag="ON488_002803"
     CDS             6937..7593
                     /locus_tag="ON488_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HCR3232899.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            7775..8305
                     /locus_tag="ON488_002804"
     CDS             7775..8305
                     /locus_tag="ON488_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HCR3232900.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            8851..9093
                     /locus_tag="ON488_002805"
     CDS             8851..9093
                     /locus_tag="ON488_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HCR3232901.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            9090..9560
                     /locus_tag="ON488_002806"
     CDS             9090..9560
                     /locus_tag="ON488_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HCR3232902.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWGKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
BASE COUNT         3434 a         1419 c         1904 g         2995 t
ORIGIN      
        1 ctcgagttac gagtttggaa cagcttttgt ctacagtctg tcattattat caaaataatg
       61 ttaaaaataa aaaagaattg tccatcactg ttattcaaat cattttatca aaactacata
      121 gtaaatgtta aaaagcaaca tgacataata tatagaaggc tttacagtat atatgggagc
      181 ttactaaaaa agaatggagt aagagttaac acaatgggcc attagctgaa gttttaagca
      241 cttcaaggta tgaaacagaa tggcctgtaa tactacatga ttatttagac tgctcaaact
      301 gctatcagtc tggtggaatg aataaagtat tatactaaaa gcagatccaa ctacaacgta
      361 acaggaaacc agttgtatca ggaaaagtga tagtacatgg agaagaaaag gccccctttg
      421 tatgagtcag tacatatctt atttatagat aaaacggtat tcaatcgaaa taaaaaatct
      481 gaataataga cgtaaataac ttctaaaagt ctcacacatc tatcattcag attatttttt
      541 atttactgtt tgttctactt tattttattc ttctggtata gtattcgagt catttttata
      601 ggtcaacaaa tcacctggtt gacactccaa aacttggcag attttttcga gagtggaaaa
      661 acggatggct tttgcttttc cattttttag aatagagatg tttgccatcg taatgcccac
      721 tttctcactc aattcagtca cactcatttt tttttgagct aatactacat ctaaattaac
      781 gataattgcc atgtcgcacc tcacactgtc aaatcatgat ctgtcttaag taaaatcgca
      841 tgttcaagca gtttttccag cacgcttgtt aatgtgtata ctgcaaaagg aatgaatacg
      901 acagcgattc ctaccaacat caaacctgga gcatcgtcta aatccgctac tttcataaat
      961 ttaggaagta agccaaaaaa ggcgaaacca ataaacaaaa tggttcgttc gatttttttt
     1021 agtatgttta agctttgagt ggaaaaagct tggttatctt cgattttttt caatagtttc
     1081 aataagaaat aagcaataac gatccctagg agaagggcaa agtaaatgac agaaacaaat
     1141 aatgtggtct gccaatcaaa attgaatcct ttttcgcttg tagcgatctg agtataaaaa
     1201 agtacgccga acaaaataaa tacggcactt atacctaaaa cgacaaattt taatagcaat
     1261 gttttaaatt tcatttttat ccctctttta tctttgatag ctaaaatata gcagaataat
     1321 tattgtaaaa caactatttt ttatcgaaaa acaataaaaa tatatcgttt ataaaaaatg
     1381 atagagtatg aaggtgtgga gtgcatttaa cagctttttt tgattgtaag aaacatttaa
     1441 aaccagttat tttagattct atgtgtgtct cttctataat gctagtttag atgcctggga
     1501 ttatattgga caatacagtt ggaggatttt ttattatcta gcgaagagaa gtgtaagtta
     1561 acagaactgt atgagaaaaa agacaactac gtagtagcta accgattcat taattttttc
     1621 aagttcatgt ttatttacgt atcagaattt ttcttattca atggtttggt gtaatcacca
     1681 cttatttgtc ctttattgct tatacaatgt tatacaaaag gaaaatcaag cattgacgca
     1741 tggggtggta ctatctagct gaaatagctt aataagcgca agtagatgca ttggattagt
     1801 ttataaatca aaagtgttag aggtattaag aagaagtaga aaaataaaat ggattgccga
     1861 ataaaaagta ccataaatcc taaaacatgt gccaacagat agatggcaca tgtttatttt
     1921 tttcgataat tttgtaacaa aaatacgaag atgaaaaaga atagagattc ccataatgta
     1981 gtagtccaac tgaattcttt actgatacca aataccatat ttcctagatt tgatacaatc
     2041 aaatagccaa tcgttatgat caatgaatag tacaatcttt tcatcatagg acatacctcg
     2101 tttttattta taagaatagt ataaaccaaa gaagtgaata agaaaaatga taatataaaa
     2161 ataaagtaag aacgcattaa agtaactaaa gttatttatt gtatttttta attctccgaa
     2221 aaaatttaat aaataaatag aatcttgtaa taataactga gcataatctt tgcaattttt
     2281 aatcttgaat aatatccttt aagtatagcc agcaatcaaa agtaaataga gaataagtaa
     2341 gcaattgtta tttcagtatc agactggcaa taaaacgccg ttatgatcca gcaatgtttg
     2401 gtagcgcttt atttactgat gctatgctaa ctgttcgcta tctatactgt gattgtcggt
     2461 agagttattt acagggtaaa aataagttta taggaggtgg aaaatgaata aggggttaaa
     2521 aataatcggt gttatcatga gtttactgct actttcagta tttctagcga ttgcgttgat
     2581 caatgcgccg tatattatgc ctgaacaatt ggaacgattt cgcttcttta ctttaacgaa
     2641 ttactacatg caacaatata ttttctgggc agctgtagta tttgccgttc ttgctattat
     2701 catcttgcta gtcgttcttt tctatccaaa gtcaagagga actttcgtta tgaaacggga
     2761 agatggcaaa ctaacaatcg acaaaaaagc gatcgaaggg ttggtacgtt cccatttaca
     2821 cgaagaagag ttcattcatt cacctaaagt acggatacgt tcaacgaaaa atcgaatcca
     2881 tatccatgtc aacggagact tgaaacgaac ttcttcatta gtagggaaaa caggtgtatt
     2941 gatgcaagat atcgaagaag aagtaactaa agtactcgga acaaaagaaa cggtcaaagt
     3001 ggcagtcaca tacagcggtt atgaagaaca agaagataca agagactaca agcactctcg
     3061 agtggaatag gagggccaaa taatgaaaga actattttca gcatacaagc tccctattat
     3121 ctttgggggt cttggactac tgctagctgt tttatggtta acgattggat ttttcaagac
     3181 attgttgatc ataatcatga cagcaattgg cgcaggaatc ggtttttatt tgaaacagtc
     3241 aggaatagtt gatcaatttt ttaaatcata ggaggaaaca aagatggaaa acaaaaacat
     3301 gaatacaaca aatggatcag ttttggcaaa tgaaaaagga gaaaaccgca tgatgaatgg
     3361 tgaattgact tatgaagaca aagtcatcca aaaaatcatc ggttatgcat tgaaagatgt
     3421 agatggtcta ttgacattag atggcggatt tttctcaaat atggctgaaa aattagtcaa
     3481 cacagataac gtaacagcag gtatcaatac agaagtaggt aagaaacaag tagctgtgga
     3541 tctagatgtg atcgtagaat acggtaaaga catcgaagat atttacaacc aaatcaaaga
     3601 attgatcagt actgaagtaa acaatatgac acatttagat gttatcgaag tgaatgtgaa
     3661 tgttgcagac atcaaaacac aagaagaata ccaaaaagat caagaaacag tacaagacaa
     3721 agtaacagaa gcagcaaaat ccacaggaca atttgcttca cgccaaacag ataaagcaaa
     3781 atctgctgta ggcaaaggtg cacaaaaagt caaagaaaat aacgaaccac gtgtacaata
     3841 agaagtaaga agtcagttag gaggaattta aaatgggatt tatttgggca ttaatcgtcg
     3901 gcggtatcat tggagcaatt gcaggagcaa tcacgaataa aggatcatca atggggatca
     3961 tcgcaaacat cattgctggt ttagtaggtt cagcaattgg acaagcttta ctaggaactt
     4021 ggggaccaac aattgcagga atggctatca ttccatcatt gatcggtgca atcattttag
     4081 tattagtcgt ttcattcttt gcacgtaaat tataagcaaa ttgaagaaaa acttatgttg
     4141 aaatgaagaa caaatttgag aaccgtagcg acactcgctg cggttctttt ttatatattt
     4201 tatatgaagt attctttatt ccttatgaaa aaatatcttt aaaaataaaa aaagacgaaa
     4261 ataaacggtt ttctataaaa agaagaccgt ttattttttg tctttatttg tgtgaaaaac
     4321 gaaaaagagc acaacacatc aagcttttat taattgtctg tcttttataa atgcaagtat
     4381 taattcaaaa aaacagaaga aaaaaacaac tacaccttct tttatactcg taatcgtaga
     4441 aaggaggcga aaaaaatgaa tacattacct atcaatacag gagatacagc attcatgatt
     4501 ttatgtacag caatggtttg cctgatgact cctggtctag ctttttttta cgcggattag
     4561 cacggaagaa taatatacta acgatcatgt ctcaatcttt tctctccgtt gggataacaa
     4621 cgattatgtg ggtatttggt ggattcggat tggcctttgg acgggatatc ggcggtgtta
     4681 ttggaaaccc ggcagatttc tttttgatga gacatgttac aagcttcccc aacatgtttc
     4741 atggtgcaac gattccattt ttaatgttct ttctttacca actgatgttt atcgtgatta
     4801 ccgttccttt gatgacagga gcttttgcag ggagattgaa tttaaaaggc tatattatac
     4861 ttgttatttt ttggaatctg ctgatttatt tccctgtttg ccactggata tggggtggcg
     4921 gatttttgga tcagatggga tttagagatt tcgctggtgg agcagtcatc cacacgacag
     4981 ctggattcgg ctctttagca tgtatcctca cacttggtca aagaaagatt cctttaggag
     5041 aaagaagtca gcatagcagt cttatggcag ctgctatcgg tacaggactg ctttggtttg
     5101 gctggttcgg ttttaattcc ggtggtgcac ttcgagcaga tgaacaagca gtcaatgcat
     5161 ttggttcaac attcatcgct cttgcatttg cgatgattac ttggctgatc attgcaaaag
     5221 taaaaggaaa tggctttgat tttgtcgacg tactaacagg atccgttgct ggattggcag
     5281 ccattacgcc ttgtgccggt tatgtagaag caaaaagtgc catgctgatt gggatcattg
     5341 cgggtatcgt ctgtcatgct gctgttgatt ttcgtaaaaa gaaacaatgg gatgatgcac
     5401 ttgatgtgtg gggtgttcat ggcatgggcg gattcacagg tacgattctg atagggatct
     5461 ttgcatctaa cagccattta ctaacgaatc caagcagctg gtacttctta gggattcaag
     5521 tgattggtgt catcattact gccgtgtatg cctatgtgct gacaacagtg attttaaaat
     5581 cggcgatgca ctttacaacg atcactacta caaaagaaga acaagaagaa ggattggact
     5641 ttttcttctt tggcaacaaa ctcaattgaa acaaattcaa atagaaaaga ggaagattca
     5701 tgcaacaaag caaaacgaaa attcctgcaa aaaaattaac gttctttggc tttttggcta
     5761 tgaccatctc aatggtcgtt tcattatatg aatatcccac attcgcgacc tcaggcttca
     5821 gcttagtatt tttcttgtta ttaggcggtt tgctatggtt tatccctgtg gcattgtgcg
     5881 cagcagagat ggcaacggtg aaaggatggg aaaaaggtgt ttcccaaaca aaaagatatt
     5941 aagaaacagc ccatgtttac ctgcttgcaa acaaaagaat attgctacta gactaagaga
     6001 tactacataa gtgtgttggt atctcttttt tgttgccgtg aaacagcaga ctatttcatt
     6061 tctgcttgat taccttaaaa cttattagtc tatggtttgt caagggcttg ttgcgtgaga
     6121 aatgctgaat atcacccttt acaaaacata ggctgataag taacttttca aaagcagaaa
     6181 agaaatggca atgcttataa caatatgata taatgcagat gaagacaaaa aaggaatttg
     6241 tcgagctggt tagttcgaga taattttgag tttgttaaga tgtggtgcac ttgatggaat
     6301 cacaggtacg acatcatatt atggaggatg aaatagatga taggtttgat tgttgcgagg
     6361 tcaaagaata atgttatagg caagaatggt aatataccat ggaaaataaa gggagaacaa
     6421 aagcaattta gagagttaac aacgggtaat gtggttatta tggggcgaaa gtcttatgaa
     6481 gaaatcggtc atccgttgcc taatagaatg aatattgttg tttccaccac aacagagtat
     6541 caaggagata atttagtttc agttaaatca ttagaagatg cattattatt ggctaaagga
     6601 cgagatgtat acatatctgg tggatatgga ctatttaagg aagctttgca aatagtagat
     6661 aaaatgtata tcacagaagt agatttaaat attgaagatg gagatacatt ctttccagaa
     6721 tttgatatca atgattttga agttttgata ggggaaacac ttggtgagga agtgaaatat
     6781 acgagaacat tttatgtaag gaaaaaatga attgagtaaa ttttggattt agggtgtttt
     6841 cataaatata ttgcttttta tgcatatata aattgttgta agacaaattc cagtttgtat
     6901 ggggcgataa aatcagaatt tgagagagga ttgaatatga ataaggaatg gtctgaactt
     6961 aataaaacaa tgcaggcaca aataaaaaag aaagatactt ataagagggg tattgatact
     7021 ttacttactt tacgaagtca gttaatacaa accttagtat ctttcaaaga agaattatgc
     7081 agagaagatt ttaactcaat ccccttcata aacgctgatg gttatcatag taagacgatt
     7141 gcttattcta tttggcatat tttccgcatt gaagatatag ttgtgcatac agtgataaat
     7201 gaagatgaac aagtattttt tgcaggcaat tatcaagagc gtatcaattc acctatcatt
     7261 acaacaggaa atgaactcat gaaacagcag attgcagact tttcaaaaca gcttaatctg
     7321 gaagaattat atttatatat tttcgaagta tgggaaagca ctgagaaaat gcttgaacgg
     7381 ttatcttatg atgaattgaa aagaaaaata ccgaaagaaa gaaaaggata cttagaatcg
     7441 ttgaatgtag taaacgacaa tgaaaaagca atttggctga ttgattattg gtgtaataaa
     7501 gatatttgtg gactaattca aatgccgttt tcaagacatt ggattatgca cacagaagcc
     7561 tgtttgcgta taaagaacaa gatacattca taggcaaaaa tttcagtttg tagaactaag
     7621 gaaattggaa tttaaggagg aataaagtat ggttagtgat tttataagag cagcatttcc
     7681 atggatttta atgggtttat ttgtagcaat cagttgttcc cttatgagta aaaaagagaa
     7741 ataaattcct gtttgtattt ataaaagaga aaaaatgaga aaagtagttt tatttattgc
     7801 catgagcctt gacggatata ttgcggacgg taatggtgga gtagcttggc taaatggtca
     7861 tggaaatgac aatgaaaaca tcgacactta tacagaattt accaaagata tagatactgt
     7921 cttaatgggg tggaatactt ctcatcaggt tgttactgaa ctttctccgc aagaatgggt
     7981 atataataaa tttacaactt atgtattaac acataaagag tgcaattctt cccaacaaat
     8041 tcattttaca agtgaaaatc ctgttttatt attggaacgg ctaaaacaag aagcaggaaa
     8101 ggatatttgg atttgtggcg gagcaaatct tgttcagcag ttggtaagca aaaatatgat
     8161 tgataaatat tacatttctg ttattcctac tctgttagga aatggggttc gtcttttggg
     8221 caacatagac agggaaataa agttaaggct ttgtaaaaca cagacttata acggaataac
     8281 cgatttgatt tatatgcgta gataactaga gagaaacaga aaagctgtta aaccgacgga
     8341 gcgatccgac cacgttggcg ggaaaatcct taagattttt ccgccatgct tgcaaggggg
     8401 cggttcgctt cggcggttcg gcgagcttgc gagccgttca aagcccccgt tatctaacaa
     8461 ggggggcaca aaaaacaaga aacactatac actaacaagc ggaaaacgct gtatttataa
     8521 ggcaaaaccc catttttaca gtagtgatat aaattgtacc tatatcacta tgaaaattga
     8581 atagtaaata tgagaaagac agttgatttc aaaaaataag aaattgattg tcgttttctt
     8641 ttgcagaaat ttaagtgcag gcaattatgg tagttgtcgt aattgctgtc agctcagtgt
     8701 ttatcactga tggtgtgaaa gatttacggt tggagatgtt caataagatt attggtgctt
     8761 aattattttt attgtagtgc tgatatgaga atgttataat tggggtataa aacatacaaa
     8821 taaatttgct gaaaaatgag gtatcaaaat atggaaaatg aattactgga aaacttagga
     8881 agacttcaca caactgaact tggcgttatt agaattaaaa agaacttatc tttgaatgta
     8941 gaaaatgtaa ttgaatggtg caaagaaaaa attagccttt ctaatgcgga aatcacaaga
     9001 aaaggaaaaa actggtatat aacgattgat aattgtatta taacggtaaa tgcgtacagt
     9061 tataccgtta tcactgctca caaggtaaaa tgataaattt ttctataaag gaattaaacg
     9121 catttgcagt tattgggcag gaagtagaac tgactaatta tcaaaaaaag aatattcaga
     9181 ttagtacaca gttttgggga aagtttaaca gtagtttgaa aaaagcgtat ctttcacaat
     9241 caggaaattg ggtaaaatat gcttttatgg aaagaagaaa tggaaaactt tattatttct
     9301 gttctattcc ccaaagaacc attaccccag agggctttct gtataaagaa ataccgtctt
     9361 ataaatattt ggttgtggag catattggtg ctatggataa aatatatgaa acttatggca
     9421 agatttatga agaaattatt cctagtacat cgtatattcc tataaaagat attatcctac
     9481 actttgaaaa atacgattat cgttttcatt ggaatagtga taattcagtt attgaaattt
     9541 ggatacctat tcaagattag aagcaatttt atatccatac acacaaagca gttagtctta
     9601 ggattgactg ctttttctat acagattttt aatgacaggc aattatcaat tatggtagtt
     9661 gccttttttg attggaggaa ttgaagaatg aatgataaaa actttattga aggtaagcgc
     9721 cccatagaac agtaccttac taacaaatgc ac
//
LOCUS       DAJSMK010000233         7317 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.106, whole genome shotgun sequence.
ACCESSION   DAJSMK010000233 DAJSMK010000000
VERSION     DAJSMK010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.106"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            <1..572
                     /locus_tag="ON488_002807"
     CDS             <1..572
                     /locus_tag="ON488_002807"
                     /inference="COORDINATES: protein
                     motif:HMM:NF013677.1,HMM:NF024908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HCR3232903.1"
                     /translation="DFILYLKLCNRTYRSYSKEFKQKIVAEYLQTGYGFSYLAAKYNI
                     PSKTTVNKWVIRYTEGKENETYSPKSEVYNMTGVKKSYEEKLKIVEDYIANRLTYLEA
                     AEKNHVSYSNIYSWVNKYKKHGPIGLEDNRGRGKPTEIQTTEERLNAEVETLKARNKW
                     LEMENDALKKRRKIAGNHKSQGLDKKWNI"
     gene            560..1420
                     /locus_tag="ON488_002808"
     CDS             560..1420
                     /locus_tag="ON488_002808"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HCR3232904.1"
                     /translation="MEYLTIEELKHKYPVIHLCDILGIAKSSYYKWLKREPSETELKR
                     LKLMRAIKGIHEAFGGIYGYRRMTIFLNFFRRAKVNHKCVHRLMRIMGITAVIRRKRR
                     NYVPHKAVHVAENILNRDFHAERPMEKLLTDVTEFRLTNGTKRYLSAIYDLGSKKIVA
                     YKTSHRNDNPLVLDTLKQILGDVKPETTLIHSDRGSQYTSHAFNKMIKDHQIIHSMSR
                     VSKCIDNGPMEGFWGTLKVEMFNLDTFDRPAYLDRKIKAYIAFFNNERVTLDMGLAIP
                     TEEKILQMIA"
     gene            complement(1505..4429)
                     /locus_tag="ON488_002809"
     CDS             complement(1505..4429)
                     /locus_tag="ON488_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HCR3232905.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SE"
     gene            4575..5150
                     /locus_tag="ON488_002810"
     CDS             4575..5150
                     /locus_tag="ON488_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HCR3232906.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            5364..6059
                     /gene="vanR"
                     /locus_tag="ON488_002811"
     CDS             5364..6059
                     /gene="vanR"
                     /locus_tag="ON488_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HCR3232907.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGDVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            6037..7191
                     /locus_tag="ON488_002812"
     CDS             6037..7191
                     /locus_tag="ON488_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HCR3232908.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
BASE COUNT         2322 a         1400 c         1425 g         2170 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccta ccgcagttac tcgaaagaat
       61 tcaagcagaa aattgtagct gaatacctac agacgggtta cggtttttca tacttagccg
      121 ctaaatataa cattccatct aaaacaacgg taaacaaatg ggtaattcga tatactgaag
      181 gaaaagagaa tgagacatat tctccgaaat ctgaggtgta caacatgacg ggtgttaaaa
      241 aatcatatga agaaaaatta aaaatcgtag aagattacat agccaatcgc ctgacttatc
      301 tggaagcagc ggagaaaaac catgtaagtt acagtaacat ttattcctgg gtgaataaat
      361 acaaaaagca tggaccgata ggtctggaag acaaccgggg ccgcgggaag cccacggaaa
      421 ttcaaacaac ggaagaacgt ttaaacgcag aagtagagac actcaaagcc cggaacaaat
      481 ggctagaaat ggagaacgat gcgttaaaaa agcgccgaaa aatcgctggg aatcacaaat
      541 cacaggggtt agacaagaag tggaatattt aactattgaa gaattaaagc ataaatatcc
      601 cgttatccat ctttgtgaca tactgggtat cgccaaatcc agctactata agtggttaaa
      661 acgggaaccc tcagaaacag aattaaaacg cctgaaactg atgcgggcga tcaaaggaat
      721 ccacgaggca ttcggtggga tttacggcta ccgaagaatg accatctttc tcaacttttt
      781 tagaagagcg aaagtgaatc ataagtgtgt acaccgcctc atgagaatca tggggatcac
      841 agccgtcatc cgtcgcaaaa gaaggaacta cgtgccacac aaagccgtac atgtggctga
      901 aaacatctta aaccgtgatt tccacgctga aagacccatg gaaaagttat tgacggatgt
      961 cacggaattc cggttgacca atgggacaaa acgttacctg agcgctattt atgacctcgg
     1021 gtcaaagaaa atcgtggctt ataaaaccag tcaccgcaat gacaacccgt tagtactgga
     1081 tacactaaag cagattttgg gtgatgtaaa gcctgaaacc acactgattc atagcgaccg
     1141 cggttcccag tacacctccc atgcctttaa caagatgatt aaagatcacc agataatcca
     1201 tagtatgtca cgcgtctcga aatgtattga caacggccct atggaaggct tttggggtac
     1261 cctcaaggtg gagatgttta acctggatac gtttgacaga ccagcgtact tagaccggaa
     1321 aatcaaggca tacatcgcgt tcttcaacaa tgaacgcgtt actttggata tgggattagc
     1381 aattcctacg gaagagaaga ttctacaaat gattgcataa acgctacaaa aaaagaccac
     1441 acatttttac atgcatggtc taaaatactt tgttttttta cctgtctact tgacaggggg
     1501 cagttcactc tgagttaaaa tggtattctc ctagtaaatt aatatgttcc caacctaagg
     1561 gcgacatatg gtgtaacaaa tcttcattaa agctacctgt ccgtttttta tattcaactg
     1621 ctgttgttag gtggagagta ttccaaatac ttatagcatt gataattatg tttaaagcac
     1681 tggctctttg caattgatgc tgtatggtgc gttctctaag ctcaccttgt tttccgaaga
     1741 aaatagctct tgccaatcca ttcatggctt ctcctttatt caatcctctt tgtatttttc
     1801 ttcttaatga ttcatccgat atataattca aaataaagat cgttttttct attcggccca
     1861 tctcacgtaa ggctgtagct aagctgtttt gtcttgaata ggaacctagc ttccccataa
     1921 taagggatgc tgaaactgtt ccctccctta tagaatgagc taatcgcaaa acatcctcat
     1981 aattttcttt aatgaccttt gtatttattt gtccacgtaa aatggcttct agttttggat
     2041 actcacttgc tttatctatc gtaaataatt ttgagtccga taaatccctt attcttgggg
     2101 caaatttaaa tcctaataaa tgagtcagtc cgaatatttg gtcagtgtaa ccggcagtgt
     2161 ctgtataatg ttcctctatg tttagatccg tctcatgatg taacaaacca tccaaaacat
     2221 gaatcgcatc tcttgaatta gtatgaataa tctttgtgta gtaagaagag aattgatcac
     2281 ttgtaaatcg gtagatggtg gctccttttc cagttccata atgtggattt gcatctgcat
     2341 gtagtgatga aacacctagc tgcattctca taccatctga cgaagatgtt gtaccgtcgc
     2401 cccaatagaa aggcaattgt aatttatgat gaaagtttac taatatggct tgggctttat
     2461 tcatggcatc ttcatacatg cgccattgag atacattggc tagttgctta tatgtaagtc
     2521 cgggtgtggc ttcggccatc ttgctcaagc caatattcat tcccattcct aaaagggcag
     2581 ccatgataat gattgtttct tccttatctg gttttcgatt attggaagca tgagtgaatt
     2641 gctcatgaaa tcctgttata tgggccacat ccatgagtaa atcagttaat tttattcttg
     2701 gtagcatctg ataaaggctt gcactaaatt tttttgcttc ttctggaaca tctttttcta
     2761 agcgtgcaag tgatagcttt cctttttcaa gagaaacccc atctaactta ttggaattgg
     2821 cagctaacca ctttaacctt tcattaaagc tgctggttct ctccgttata taatcttcga
     2881 atgataaact aactgataat ctcgtattcc ccttcgattg attccatgta tcttccgaaa
     2941 acaaatattc ctcaaaatcc ctatattgtc tgctgccaac aatggaaaca tctcctgccc
     3001 gaacatgctc ccgaagttct gttaaaacag ccatttcata gtaatgacga ttaattgttg
     3061 taccatcatc ctcgtataaa tgtcttttcc atcgttttga aataaaatcc acaggtgagt
     3121 catcaggcac ttttcgcttt ccagattcgt tcattcctcg gataatctca acagcttgta
     3181 aaagtggctc atttgccttt gtagaatgaa attccaatac tcttaatagc gttggcgtat
     3241 attttcttag tgaataaaac cgtttttgca gtaagtctaa ataatcatag tcggcaggac
     3301 gtgcaagttc ctgagcctct tctactgaag agacaaaggt attccattca ataaccgatt
     3361 ctaaaacctt aaaaacgtct aatttttcct ctcttgcttt aattaatgct tgtccgatgt
     3421 tcgtaaagtg tataactttc tcatttagct ttttaccgtt ttgtttctgg atttcctctt
     3481 gagccttacg accttttgat aacaaactaa gtatttgcct atcatgaatt tcaaacgctt
     3541 tatccgttag ctcctgagta agttgtaata aatagatggt taatatcgaa taacgtttat
     3601 tttcttgaaa gtcacggaat gcatacggct cgtatcttga gcctaagcga gacagctgca
     3661 acaggcggtt acggtgcaaa tgactaattt gcactgtttc taaatccatt cctcgtatgt
     3721 attcgagtcg ttctattatt tttagaaaag tttcgggtga aggatgaccc ggtggctctt
     3781 ttaaccaacc caatatcgtt ttattggatt cggatggatg ctgcgaggta ataatccctt
     3841 caagcttttc tttttgctca tttgttagag atttactaac cgtattaaat agcttctttt
     3901 cagccattgc ccttgcttcc cacaccattc tttcaagtgt agtgatagca ggcagtataa
     3961 ttttgttttt tcttagaaaa tctatgcatt catgcagtag atgaatggca tcaccatttt
     4021 ccaaagctaa ttgatgaagg tacttaaatg tcattcgata ttcactcagg gtaaaagtta
     4081 caaagtcgta ttcacttcga atttctttca aatgatccca aagtgtattt tccctttgag
     4141 gataatgatc aagcgaggat ggactaacac caatctgttt cgatatatat tgtatgaccg
     4201 aatctgggat gcttttgata tgagtgtatg gccaaccggg ataccgaaga acagctaatt
     4261 gaacagcaaa tcctaaacgg ttttcttccc tccttcgctt attaactatt tctaaatccc
     4321 gtttggaaaa agtgaagtag gtccccagta tccattcatc ttcagggatt tgcataaaag
     4381 cctgtctctg ttccggtgta agcaattctc tacctctcgc aattttcatt cagtatcatt
     4441 ccatttctgt attttcaatt tattagttca attatatatc aatagagtgt actctattga
     4501 tacaaatgta gtagactgat aaaatcatag ttaagagcgt ctcataagac ttgtctcaaa
     4561 aatgaggtga tattttgcgg aaaatcggtt atattcgtgt cagttcgact aaccagaatc
     4621 cttcaagaca atttcagcag ttgaacgaga tcggaatgga tattatatat gaagagaaag
     4681 tttcaggagc aacaaaggat cgcgagcaac ttcaaaaagt gttagacgat ttacaggaag
     4741 atgacatcat ttatgttaca gacttaactc gaatcactcg tagtacacaa gatctatttg
     4801 aattaatcga taacatacga gataaaaagg caagtttaaa atcactaaaa gatacatggc
     4861 ttgatttatc agaagataat ccatacagcc aattcttaat tactgtaatg gctggtgtta
     4921 accaattaga gcgagatctt attcggatga gacaacgtga agggattgaa ttggctaaga
     4981 aagaaggaaa gtttaaaggt cgattaaaga agtatcataa aaatcacgca ggaatgaatt
     5041 atgcggtaaa gctatataaa gaaggaaata tgactgtaaa tcaaatttgt gaaattacta
     5101 atgtatctag ggcttcatta tacaggaaat tatcagaagt gaataattag ccattctgta
     5161 ttccgctaat gggcaatatt tttaaagaag aaaaggaaac tataaaatat taacagcctc
     5221 ctagcgatgc cgaaaagccc tttgataaaa aaagaatcat catcttaaga aattcttagt
     5281 catttattat gtaaatgctt ataaattcgg ccctataatc tgataaatta ttaagggcaa
     5341 acttatgtga aagggtgata actatgagcg ataaaatact tattgtggat gatgaacatg
     5401 aaattgccga tttggttgaa ttatacttaa aaaacgagaa ttatacggtt ttcaaatact
     5461 ataccgccaa agaagcattg gaatgtatag acaagtctga gattgacctt gccatattgg
     5521 acatcatgct tcccggcaca agcggcctta ctatctgtca aaaaataagg gacaagcaca
     5581 cctatccgat tatcatgctg accgggaaag atacagaggt agataaaatt acagggttaa
     5641 caatcggcgc ggatgattat ataacgaagc cctttcgccc actggagtta attgctcggg
     5701 taaaggccca gttgcgccga tacaaaaaat tcagtggagt aaaggagcag aacgaaaatg
     5761 ttatcgtcca ctccggcctt gtcattaatg ttaacaccca tgagtgttat ctgaacgaga
     5821 agcagttatc ccttactccc accgagtttt caatactgcg aatcctctgt gaaaacaagg
     5881 gggatgtggt tagctccgag ctgctatttc atgagatatg gggcgacgaa tatttcagca
     5941 agagcaacaa caccatcacc gtgcatatcc ggcatttgcg cgaaaaaatg aacgacacca
     6001 ttgataatcc gaaatatata aaaacggtat ggggggttgg ttataaaatt gaaaaataaa
     6061 aaaaacgact attccaaact agaacgaaaa ctttacatgt atatcgttgc aattgttgtg
     6121 gtagcaattg tattcgtgtt gtatattcgt tcaatgatcc gagggaaact tggggattgg
     6181 atcttaagta ttttggaaaa caaatatgac ttaaatcacc tggacgcgat gaaattatat
     6241 caatattcca tacggaacaa tatagatatc tttatttatg tggcgattgt cattagtatt
     6301 cttattctat gtcgcgtcat gctttcaaaa ttcgcaaaat actttgacga gataaatacc
     6361 ggcattgatg tacttattca gaacgaagat aaacaaattg agctttctgc ggaaatggat
     6421 gttatggaac aaaagctcaa cacattaaaa cggactctgg aaaagcgaga gcaggatgca
     6481 aagctggccg aacaaagaaa aaatgacgtt gttatgtact tggcgcacga tattaaaacg
     6541 ccccttacat ccattatcgg ttatttgagc ctgcttgacg aggctccaga catgccggta
     6601 gatcaaaagg caaagtatgt gcatatcacg ttggacaaag cgtatcgact cgaacagcta
     6661 atcgacgagt tttttgagat tacacggtat aacctacaaa cgataacgct aacaaaaacg
     6721 cacatagacc tatactatat gctggtgcag atgaccgatg aattttatcc tcagctttcc
     6781 gcacatggaa aacaggcggt tattcacgcc cccgaggatc tgaccgtgtc cggcgaccct
     6841 gataaactcg cgagagtctt taacaacatt ttgaaaaacg ccgctgcata cagtgaggat
     6901 aacagcatca ttgacattac cgcgggcctc tccggggatg tggtgtcaat cgaattcaag
     6961 aacactggaa gcatcccaaa agataagcta gctgccatat ttgaaaagtt ctataggctg
     7021 gacaatgctc gttcttccga tacgggtggc gcgggacttg gattggcgat tgcaaaagaa
     7081 attattgttc agcatggagg gcagatttac gcggaaagca atgataacta tacgacgttt
     7141 agggtagagc ttccagcgat gccagacttg gttgataaaa ggaggtccta agagatgtat
     7201 ataatttttt aggaaaatct caaggttatc tttacttttt cttaggaaat taacaattta
     7261 atattaagaa acggctcgtt cttacacggt agacttaata ccgtaagaac gagccgt
//
LOCUS       DAJSMK010000234         6491 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.111, whole genome shotgun sequence.
ACCESSION   DAJSMK010000234 DAJSMK010000000
VERSION     DAJSMK010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6491
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.111"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            81..1049
                     /locus_tag="ON488_002813"
     CDS             81..1049
                     /locus_tag="ON488_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HCR3232909.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            1042..2073
                     /gene="vanA"
                     /locus_tag="ON488_002814"
     CDS             1042..2073
                     /gene="vanA"
                     /locus_tag="ON488_002814"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HCR3232910.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALAVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            2079..2687
                     /locus_tag="ON488_002815"
     CDS             2079..2687
                     /locus_tag="ON488_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HCR3232911.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPNRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            3115..4026
                     /gene="vanY"
                     /locus_tag="ON488_002816"
     CDS             3115..4026
                     /gene="vanY"
                     /locus_tag="ON488_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanY-A/VanY-F/VanY-M family D-Ala-D-Ala
                     carboxypeptidase"
                     /protein_id="HCR3232912.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYELWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            4179..4664
                     /gene="vanZ"
                     /locus_tag="ON488_002817"
     CDS             4179..4664
                     /gene="vanZ"
                     /locus_tag="ON488_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HCR3232913.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(4951..5280)
                     /locus_tag="ON488_002818"
     CDS             complement(4951..5280)
                     /locus_tag="ON488_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HCR3232914.1"
                     /translation="MKKVCQVTVVHKEKVNGIKNKLDQKDFSNLLVLGKCFSDFSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVF"
     gene            5585..5914
                     /locus_tag="ON488_002819"
     CDS             5585..5914
                     /locus_tag="ON488_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HCR3232915.1"
                     /translation="MITKTRKQGNSIMLTVPKEFDVPNGVEVEAKLVENGILYEFVEP
                     KKEFFDFSEDILADILSEGYSKQEILKEFRNRKNALTSAFKSIAEDTVANSKPMTKEE
                     LAAEIGL"
     gene            5904..6191
                     /locus_tag="ON488_002820"
     CDS             5904..6191
                     /locus_tag="ON488_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HCR3232916.1"
                     /translation="MAYEILPSKHVIKYLKKLKEKTLKEQFLTIIYDEIAVRPHSGEQ
                     KTGDLSGIWAIGFKYAGTTYRVAYEIKDNAVIPILLCGTHENFYEQLKKIR"
BASE COUNT         2146 a         1074 c         1344 g         1927 t
ORIGIN      
        1 ttcagagaaa gatttgacaa gattaccatt ggcatccccg ttttatttgg tgcctttcac
       61 agaaagggtt ggtcttaatt atgaataaca tcggcattac tgtttatgga tgtgagcagg
      121 atgaggcaga tgcattccat gctctttcgc ctcgctttgg cgttatggca acgataatta
      181 acgccaacgt gtcggaatcc aacgccaaat ccgcgccttt caatcaatgt atcagtgtgg
      241 gacataaatc agagatttcc gcctctattc ttcttgcgct gaagagagcc ggtgtgaaat
      301 atatttctac ccgaagcatc ggctgcaatc atatagatac aactgctgct aagagaatgg
      361 gcatcactgt cgacaatgtg gcgtactcgc cggatagcgt tgccgattat actatgatgc
      421 taattcttat ggcagtacgc aacgtaaaat cgattgtgcg ctctgtggaa aaacatgatt
      481 tcaggttgga cagcgaccgt ggcaaggtac tcagcgacat gacagttggt gtggtgggaa
      541 cgggccagat aggcaaagcg gttattgagc ggctgcgagg atttggatgt aaagtgttgg
      601 cttatagtcg cagccgaagt atagaggtaa actatgtacc gtttgatgag ttgctgcaaa
      661 atagcgatat cgttacgctt catgtgccgc tcaatacgga tacgcactat attatcagcc
      721 acgaacaaat acagagaatg aagcaaggag catttcttat caatactggg cgcggtccac
      781 ttgtagatac ctatgagttg gttaaagcat tagaaaacgg gaaactgggc ggtgccgcat
      841 tggatgtatt ggaaggagag gaagagtttt tctactctga ttgcacccaa aaaccaattg
      901 ataatcaatt tttacttaaa cttcaaagaa tgcctaacgt gataatcaca ccgcatacgg
      961 cctattatac cgagcaagcg ttgcgtgata ccgttgaaaa aaccattaaa aactgtttgg
     1021 attttgaaag gagacaggag catgaataga ataaaagttg caatactgtt tgggggttgc
     1081 tcagaggagc atgacgtatc ggtaaaatct gcaatagaga tagccgctaa cattaataaa
     1141 gaaaaatacg agccgttata cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa
     1201 aaaccttgcg cggaatggga aaacgacaat tgctattcag ctgtactctc gccggataaa
     1261 aaaatgcacg gattacttgt taaaaagaac catgaatatg aaatcaacca tgttgatgta
     1321 gcattttcag ctttgcatgg caagtcaggt gaagatggat ccatacaagg tctgtttgaa
     1381 ttgtccggta tcccttttgt aggctgcgat attcaaagct cagcaatttg tatggacaaa
     1441 tcgttgacat acatcgttgc gaaaaatgct gggatagcta ctcccgcctt ttgggttatt
     1501 aataaagatg ataggccggt ggcagctacg tttacctatc ctgtttttgt taagccggcg
     1561 cgttcaggct catccttcgg tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca
     1621 attgaatcgg caagacaata tgacagcaaa atcttaattg agcaggctgt ttcgggctgt
     1681 gaggtcggtt gtgcggtatt gggaaacagt gccgcgttag ctgttggcga ggtggaccaa
     1741 atcaggctgc agtacggaat ctttcgtatt catcaggaag tcgagccgga aaaaggctct
     1801 gaaaacgcag ttataaccgt tcccgcagac ctttcagcag aggagcgagg acggatacag
     1861 gaaacggcaa aaaaaatata taaagcgctc ggctgtagag gtctagcccg tgtggatatg
     1921 tttttacaag ataacggccg cattgtactg aacgaagtca atactctgcc cggtttcacg
     1981 tcatacagtc gttatccccg tatgatggcc gctgcaggta ttgcacttcc cgaactgatt
     2041 gaccgcttga tcgtattagc gttaaagggg tgataagcat ggaaatagga tttacttttt
     2101 tagatgaaat agtacacggt gttcgttggg acgctaaata tgccacttgg gataatttca
     2161 ccggaaaacc ggttgacggt tatgaagtaa atcgcattgt agggacatac gagttggctg
     2221 aatcgctttt gaaggcaaaa gaactggctg ctacccaagg gtacggattg cttctatggg
     2281 acggttaccg tcctaatcgt gctgtaaact gttttatgca atgggctgca cagccggaaa
     2341 ataacctgac aaaggaaagt tattatccca atattgaccg aactgagatg atttcaaaag
     2401 gatacgtggc ttcaaaatca agccatagcc gcggcagtgc cattgatctt acgctttatc
     2461 gattagacac gggtgagctt gtaccaatgg ggagccgatt tgattttatg gatgaacgct
     2521 ctcatcatgc ggcaaatgga atatcatgca atgaagcgca aaatcgcaga cgtttgcgct
     2581 ccatcatgga aaacagtggg tttgaagcat atagcctcga atggtggcac tatgtattaa
     2641 gagacgaacc ataccccaat agctattttg atttccccgt taaataaact tttaaccgtt
     2701 gcacggacaa actatataag ctaactcttt cggcaggaaa cccgacgtat gtaactggtt
     2761 cttagggaat ttatatatag tagatagtat tgaagatgta aggcagagcg atattgcggt
     2821 cattatctgc gtgcgctgcg gcaagatagc ctgataataa gactgatcgc atagaggggt
     2881 ggtatttcac accgcccatt gtcaacaggc agttcagcct cgttaaattc agcatgggta
     2941 tcacttatga aaattcatct acattggtga taatagtaaa tccagtaggg cgaaataatt
     3001 gactgtaatt tacggggcaa aacggcacaa tctcaaacga gattgtgccg tttaagggga
     3061 agattctaga aatatttcat acttccaact atatagttaa ggaggagact gaaaatgaag
     3121 aagttgtttt ttttattgtt attgttattc ttaatatact taggttatga ctacgttaat
     3181 gaagcactgt tttctcagga aaaagtcgaa tttcaaaatt atgatcaaaa tcccaaagaa
     3241 catttagaaa atagtgggac ttctgaaaat acccaagaga aaacaattac agaagaacag
     3301 gtttatcaag gaaatctgct attaatcaat agtaaatatc ctgttcgcca agaaagtgtg
     3361 aagtcagata tcgtgaattt atctaaacat gacgaattaa taaatggata cgggttgctt
     3421 gatagtaata tttatatgtc aaaagaaata gcacaaaaat tttcagagat ggtcaatgat
     3481 gctgtaaagg gtggcgttag tcattttatt attaatagtg gctatcgaga ctttgatgag
     3541 caaagtgtgc tttaccaaga aatgggggct gagtatgcct taccagcagg ttatagtgag
     3601 cataattcag gtttatcact agatgtagga tcaagcttga cgaaaatgga acgagcccct
     3661 gaaggaaagt ggatagaaga aaatgcttgg aaatacgggt tcattttacg ttatccagag
     3721 gacaaaacag agttaacagg aattcaatat gaactatggc atattcgcta tgttggttta
     3781 ccacatagtg cgattatgaa agaaaagaat ttcgttctcg aggaatatat ggattaccta
     3841 aaagaagaaa aaaccatttc tgttagtgta aatggggaaa aatatgagat cttttattat
     3901 cctgttacta aaaataccac cattcatgtg ccgactaatc ttcgttatga gatatcagga
     3961 aacaatatag acggtgtaat tgtgacagtg tttcccggat caacacatac taattcaagg
     4021 aggtaaggat ggcggaatga aaccaacgaa attaatgaac agcattattg tactagcact
     4081 tttggggtaa cgttagcttt ttaatttaaa acccacgtta actaggacat tgctatacta
     4141 atgatacaac ttaaacaaaa gaattagagg aaattatatt gggaaaaata ttatctagag
     4201 gattgctagc tttatattta gtgacactaa tctggttagt gttattcaaa ttacaataca
     4261 atattttatc agtatttaat tatcatcaaa gaagtcttaa cttgactcca tttactgcta
     4321 ctgggaattt cagagagatg atagataatg ttataatctt tattccattt ggcttgcttt
     4381 tgaatgtcaa ttttaaagaa atcggatttt tacctaagtt tgcttttgta ctggttttaa
     4441 gtcttacttt tgaaataatt caatttatct tcgctattgg agcgacagac ataacagatg
     4501 taattacaaa tactgttgga ggctttcttg gactgaaatt atatggttta agcaataagc
     4561 atatgaatca aaaaaaatta gacagagtta ttatttttgt aggtatactt ttgctcgtat
     4621 tattgctcgt ttaccgtacc catttaagaa taaattacgt gtaagatgtc taaatcaagc
     4681 aatctgatct ttcatacaca taaagatatt gaatgaattg gattagatgg aaaacgggat
     4741 gtggggaaac tcgcccgtag gtgtgaagtg aggggaaaac cggtgataaa gtaaaaagct
     4801 tacctaacac tatagtaaca aagaaagccc aattatcaat tttagtgctg aggaattggt
     4861 ctctttaata aatttcctta acgttgtaaa tccgcatttt cctgacggta cccccaaact
     4921 aagatttcat agatagattt tctgataact ttaaaaaaca cgaatagcgg aaaggatgtc
     4981 ttcattcgct aaagagtaat aaactacttt tccatcttga cgtgattttg ccattccatg
     5041 tttttttaaa aaacgtaaat ggtgtgacgt tgtagcgaca ctagcagtaa gtatttctgc
     5101 taaatcacag acgcacattt ccttataggt ttctaaagca tagaaaattt taattctaga
     5161 aaaatcgctg aaacatttcc ctaacacaag taagtttgaa aaatcttttt gatccaattt
     5221 attttttatt ccatttactt tttctttatg tacgacagtc acttggcaaa cttttttcat
     5281 tcatctcacc tcacattcaa acgattattt gaatgaagta tacctatttg atcactcttt
     5341 tgtcaatcta ccttaattcc aatacactat tataagcaat ttcatgtatt gaagtaaact
     5401 tacttgcaag tgcgtttttg attccaagtt aaaaacatat tattattcta cataatttcc
     5461 taatcaaata aaactccttt gaaaattgtt ctaaaggagt tttattattt tgtatttcta
     5521 ctaaaaatag cgtacaatgt aattactaag taattacgaa atgtaaaata atggaggaaa
     5581 taatatgatt acaaaaacaa gaaaacaagg aaattctatt atgttaacgg tccctaaaga
     5641 attcgatgtg cccaatggtg ttgaagtaga agctaagctt gtagagaatg gtatccttta
     5701 tgagtttgta gagcctaaaa aagaattttt tgattttagt gaagatattt tggctgatat
     5761 tctttcagaa ggttatagca aacaagagat cttaaaagaa tttagaaata gaaaaaatgc
     5821 gttaacttct gcatttaaat ctattgctga agatactgtt gcaaattcta aaccgatgac
     5881 aaaagaggag ttggcagcag aaattggctt atgagattct accttctaaa cacgtaataa
     5941 agtatctaaa aaaattaaaa gagaaaacat taaaagaaca atttttaacg ataatttatg
     6001 atgagatagc agttcgtcct cattcgggag aacaaaaaac gggtgattta tcaggaattt
     6061 gggctattgg attcaagtat gcaggtacga catatcgcgt tgcatatgaa attaaagata
     6121 atgcagtgat acctatctta ctatgtggaa cgcatgaaaa tttttatgaa caattaaaaa
     6181 agattaggta agaacccaat gtttcaactt gagaggatag acgacacttt aaaagataat
     6241 ttttaacagc tgagagttgt aataccctat aattttaaac cactaaccta tatatttatg
     6301 aaaaatagaa aaaattaaaa cgcattttaa gcctctttca aattaaaagc ttcatcctta
     6361 tgcacaaaga gggcttaaaa tgcgttattt tatattgttt tttagtaata ataaaaaaat
     6421 cactctaatt ctcccataaa tattatagat tccggttctg ttgcaaagtt ttaaataaag
     6481 aataaaatcc c
//
LOCUS       DAJSMK010000235         6293 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.116, whole genome shotgun sequence.
ACCESSION   DAJSMK010000235 DAJSMK010000000
VERSION     DAJSMK010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.116"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ON488_002821"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ON488_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCR3232917.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="ON488_002822"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="ON488_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCR3232918.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3976..5238
                     /locus_tag="ON488_002823"
     CDS             3976..5238
                     /locus_tag="ON488_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCR3232919.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            5483..6286
                     /locus_tag="ON488_002824"
     CDS             5483..6286
                     /locus_tag="ON488_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HCR3232920.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLRFCCKVLNKE"
BASE COUNT         2181 a          897 c         1294 g         1921 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt tacatatgag ttatgcagtt tgtagaatgc aaaaagtgaa atcagctgga
     4021 ctaaaaggca tgcaatttca taatcaaaga gagcgaaaaa gtagaacgaa tgatgatatt
     4081 gaccatgagc gaacacgtga aaattatgat ttgaaaaatg ataaaaatat tgattacaac
     4141 gaacgtgtca aagaaattat tgaatcacaa aaaacaggta caagaaaaac gaggaaagat
     4201 gctgttcttg taaatgagtt gctagtaaca tctgaccgag atttttttga gcaactggat
     4261 ccaggagaac aaaaacgatt ttttgaggaa agttataaat tattttccga acgatatggc
     4321 aagcaaaata ttgcttatgc aacagttcat aatgatgagc aaacccctca catgcattta
     4381 ggtgttgtgc ctatgcgtga tggaaaactg caaggaaaaa atgtgtttaa tcgtcaagaa
     4441 ctgttatggc tacaagataa attccccgag catatgaaaa aacagggttt tgagttgaag
     4501 cgtggtgaac gtggctctga ccgtaaacat attgagacag ctaaatttaa aaaacaaact
     4561 ttggaaaaag agattgattt tctagaaaaa aatttagcag ttaaaaaaga tgaatggact
     4621 gcttatagcg ataaagttaa atcagattta gaagtaccag cgaaacgaca catgaaaagt
     4681 gttgaagtgc caacgggtga aaagtccatg tttggtttgg gaaaagaaat aatgaaaaca
     4741 gaaaagaaac caaccaaaaa tgttgttata tcggagcgtg attataaaaa cttagtgact
     4801 gctgcgagag ataacgatag gttaaaacag catgttagaa atctcatgag tactgatatg
     4861 gcgagagaat ataaaaaatt aagtaaagaa catgggcaag ttaaagaaaa atatagtggt
     4921 cttgtagagc gatttaatga aaatgtaaat gattataatg agttgcttga agaaaacaag
     4981 tctttaaagt ctaaaataag cgatttaaag cgtgatgtga gtttaatcta tgaaagcact
     5041 aaggaattcc ttaaggaacg tacagacggc ttaaaagcct ttaaaaacgt ttttaagggg
     5101 tttgtagaca aggtaaagga taaaacagca caattccaag aaaaacacga tttagaacct
     5161 aaaaagaacg aatttgaact aactcataac cgagaggtaa aaaaagaacg aagtcgagat
     5221 cagggaatga gtttataaaa taaaaaaagc acctgaaaag gtgtcttttt ttgatggttt
     5281 tgaacttgtt ctttcttatc ttgatatata tagaaataac gtcattttta ttttagttgc
     5341 tgaaaggtgc gttgaagtgt tggtatgtat gtgttttaaa gtattgaaaa cccttaaaat
     5401 tggttgcaca gaaaaacccc atctgttaaa gttataagtg accaaacaaa taactaaata
     5461 gatgggggtt tcttttaata ttatgtgtcc taatagtagc atttattcag atgaaaaatc
     5521 aagggtttta gtggacaaga caaaaagtgg aaaagtgaga ccatggagag aaaagaaaat
     5581 cgctaatgtt gattactttg aacttctgca tattcttgaa tttaaaaagg ctgaaagagt
     5641 aaaagattgt gctgaaatat tagagtataa acaaaatcgt gaaacaggcg aaagaaagtt
     5701 gtatcgagtg tggttttgta aatccaggct ttgtccaatg tgcaactgga ggagagcaat
     5761 gaaacatggc attcagtcac aaaaggttgt tgctgaagtt attaaacaaa agccaacagt
     5821 tcgttggttg tttctcacat taacagttaa aaatgtttat gatggcgaag aattaaataa
     5881 gagtttgtca gatatggctc aaagatttcg ccgaatgatg caatataaaa aaattaataa
     5941 aaatcttgtt ggttttatgc gtgcaacgga agtgacaata aataataaag ataattctta
     6001 taatcagcac atgcatgtat tggtatgtgt ggaaccaact tattttaaga atacagaaaa
     6061 ctacgtgaat caaaaacaat ggattcaatt ttggaaaaag gcaatgaaat tagactatga
     6121 tccaaatgta aaagttcaaa tgattcgacc gaaaaataaa tataaatcgg atatacaatc
     6181 ggcaattgac gaaactgcaa aatatcctgt aaaggatacg gattttatga ccgatgatga
     6241 agaaaagaat ttgaggttct gttgcaaagt tttaaataaa gaataaaatc cct
//
LOCUS       DAJSMK010000236         6293 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.117, whole genome shotgun sequence.
ACCESSION   DAJSMK010000236 DAJSMK010000000
VERSION     DAJSMK010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6293
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.117"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="ON488_002825"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="ON488_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HCR3232921.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="ON488_002826"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="ON488_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HCR3232922.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            3976..5238
                     /locus_tag="ON488_002827"
     CDS             3976..5238
                     /locus_tag="ON488_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HCR3232923.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            5483..6286
                     /locus_tag="ON488_002828"
     CDS             5483..6286
                     /locus_tag="ON488_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HCR3232924.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLRFCCKVLNKE"
BASE COUNT         2180 a          897 c         1295 g         1921 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaggaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata gtgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt tacatatgag ttatgcagtt tgtagaatgc aaaaagtgaa atcagctgga
     4021 ctaaaaggca tgcaatttca taatcaaaga gagcgaaaaa gtagaacgaa tgatgatatt
     4081 gaccatgagc gaacacgtga aaattatgat ttgaaaaatg ataaaaatat tgattacaac
     4141 gaacgtgtca aagaaattat tgaatcacaa aaaacaggta caagaaaaac gaggaaagat
     4201 gctgttcttg taaatgagtt gctagtaaca tctgaccgag atttttttga gcaactggat
     4261 ccaggagaac aaaaacgatt ttttgaggaa agttataaat tattttccga acgatatggc
     4321 aagcaaaata ttgcttatgc aacagttcat aatgatgagc aaacccctca catgcattta
     4381 ggtgttgtgc ctatgcgtga tggaaaactg caaggaaaaa atgtgtttaa tcgtcaagaa
     4441 ctgttatggc tacaagataa attccccgag catatgaaaa aacagggttt tgagttgaag
     4501 cgtggtgaac gtggctctga ccgtaaacat attgagacag ctaaatttaa aaaacaaact
     4561 ttggaaaaag agattgattt tctagaaaaa aatttagcag ttaaaaaaga tgaatggact
     4621 gcttatagcg ataaagttaa atcagattta gaagtaccag cgaaacgaca catgaaaagt
     4681 gttgaagtgc caacgggtga aaagtccatg tttggtttgg gaaaagaaat aatgaaaaca
     4741 gaaaagaaac caaccaaaaa tgttgttata tcggagcgtg attataaaaa cttagtgact
     4801 gctgcgagag ataacgatag gttaaaacag catgttagaa atctcatgag tactgatatg
     4861 gcgagagaat ataaaaaatt aagtaaagaa catgggcaag ttaaagaaaa atatagtggt
     4921 cttgtagagc gatttaatga aaatgtaaat gattataatg agttgcttga agaaaacaag
     4981 tctttaaagt ctaaaataag cgatttaaag cgtgatgtga gtttaatcta tgaaagcact
     5041 aaggaattcc ttaaggaacg tacagacggc ttaaaagcct ttaaaaacgt ttttaagggg
     5101 tttgtagaca aggtaaagga taaaacagca caattccaag aaaaacacga tttagaacct
     5161 aaaaagaacg aatttgaact aactcataac cgagaggtaa aaaaagaacg aagtcgagat
     5221 cagggaatga gtttataaaa taaaaaaagc acctgaaaag gtgtcttttt ttgatggttt
     5281 tgaacttgtt ctttcttatc ttgatatata tagaaataac gtcattttta ttttagttgc
     5341 tgaaaggtgc gttgaagtgt tggtatgtat gtgttttaaa gtattgaaaa cccttaaaat
     5401 tggttgcaca gaaaaacccc atctgttaaa gttataagtg accaaacaaa taactaaata
     5461 gatgggggtt tcttttaata ttatgtgtcc taatagtagc atttattcag atgaaaaatc
     5521 aagggtttta gtggacaaga caaaaagtgg aaaagtgaga ccatggagag aaaagaaaat
     5581 cgctaatgtt gattactttg aacttctgca tattcttgaa tttaaaaagg ctgaaagagt
     5641 aaaagattgt gctgaaatat tagagtataa acaaaatcgt gaaacaggcg aaagaaagtt
     5701 gtatcgagtg tggttttgta aatccaggct ttgtccaatg tgcaactgga ggagagcaat
     5761 gaaacatggc attcagtcac aaaaggttgt tgctgaagtt attaaacaaa agccaacagt
     5821 tcgttggttg tttctcacat taacagttaa aaatgtttat gatggcgaag aattaaataa
     5881 gagtttgtca gatatggctc aaagatttcg ccgaatgatg caatataaaa aaattaataa
     5941 aaatcttgtt ggttttatgc gtgcaacgga agtgacaata aataataaag ataattctta
     6001 taatcagcac atgcatgtat tggtatgtgt ggaaccaact tattttaaga atacagaaaa
     6061 ctacgtgaat caaaaacaat ggattcaatt ttggaaaaag gcaatgaaat tagactatga
     6121 tccaaatgta aaagttcaaa tgattcgacc gaaaaataaa tataaatcgg atatacaatc
     6181 ggcaattgac gaaactgcaa aatatcctgt aaaggatacg gattttatga ccgatgatga
     6241 agaaaagaat ttgaggttct gttgcaaagt tttaaataaa gaataaaatc cct
//
LOCUS       DAJSMK010000237         4755 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.137, whole genome shotgun sequence.
ACCESSION   DAJSMK010000237 DAJSMK010000000
VERSION     DAJSMK010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.137"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            171..836
                     /locus_tag="ON488_002829"
                     /pseudo
     CDS             171..836
                     /locus_tag="ON488_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            872..1117
                     /locus_tag="ON488_002830"
     CDS             872..1117
                     /locus_tag="ON488_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HCR3232925.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            1220..2089
                     /locus_tag="ON488_002831"
     CDS             1220..2089
                     /locus_tag="ON488_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HCR3232926.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            2070..2804
                     /locus_tag="ON488_002832"
     CDS             2070..2804
                     /locus_tag="ON488_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HCR3232927.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            2837..3745
                     /gene="ant(6)"
                     /locus_tag="ON488_002833"
     CDS             2837..3745
                     /gene="ant(6)"
                     /locus_tag="ON488_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HCR3232928.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKGGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            3742..4284
                     /gene="sat4"
                     /locus_tag="ON488_002834"
     CDS             3742..4284
                     /gene="sat4"
                     /locus_tag="ON488_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HCR3232929.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            4377..4715
                     /locus_tag="ON488_002835"
                     /pseudo
     CDS             4377..4715
                     /locus_tag="ON488_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="APH(3') family aminoglycoside
                     O-phosphotransferase"
BASE COUNT         1657 a          689 c         1026 g         1383 t
ORIGIN      
        1 aatcaattct gattcatcag tcccataaat tatagagcct gaaaaataga ggtctttcca
       61 tttagatagt agtggaaaga cctctattta tcttttgaaa gtgaatacaa aaataaagca
      121 cactctgcta taatataggt gattaatcca tttgagagag gtgctttatc atgtatcaaa
      181 attataccat aaaccaactt tgtttgccta tagatcttga aattaaatta gaagaaaatg
      241 attttgctca tgccattgtg cagtttgttg actctattcc cgatgaagtc tttcttcctt
      301 attatcaatc tatgggtaga ccccaatatc atcctcgtat gctactttcc attattcttt
      361 gtgcctatat tcaaggggtt tattcgggcc gccaaataca aaatatgctg atagatagta
      421 ttcggatgcg ctacttatct caagagcaat tccctaactt tcgtactatt aatcgttttc
      481 gcgttcatcc gattatgaac gatattctag atcattcatt tgttcaattt cgtgagctac
      541 tggttcaaag tggcttaatc agtggcagtg ctctatacat tgatggtaca aaaattgaag
      601 cggatgcgaa taaatactct ttcgtttgga aaaaaagtat tttaaagtat aaggatagcc
      661 ttgatcaaaa agcccttgaa aactaccaac aaatggtgga aacaaaaatc ttacctgagt
      721 taatagatga tttaaaggat gaactttcta tagaagagat tgaaaggatt cgtcaatctt
      781 tggaagaaaa ggaaaatcaa ttaattgaag cgattgacca aaccgaaaca gtagaagggg
      841 gctgacccat tattaataag gagtggacaa catgattgat gtaaatgagc tattggaaga
      901 agctattaga gaaactgaaa atctaaatga tggcgaagtt tttcttgtta aagatttatt
      961 caagggatat gtggggaata ggatacccag aaaggatcga cttctgcttg gaacgttatt
     1021 tttaaaccat gttagcaaaa tgaatggtaa tttaaaggct attgaaaaga cttcatctaa
     1081 tcagcagagg tataaaaaga caattgataa gttttaacta tcttttgtga aattaaaaaa
     1141 attataaata tgttgagtag aagcaaaaga tttggcttgg aatttttaca gcagtgaatc
     1201 gataaaagga gcatgcttga tggtagataa tattattaaa tcagtagcag agaaattatc
     1261 ctctctgtct tatatagaag gtattgtttt aggtggttca cgtgcaaggg gcacccatac
     1321 agaggattcg gatatagata tcggcatcta ttacaattca gaatcatttg acataaatac
     1381 tattaatcaa ttcgctacaa agctggatga tgagcataga aataaccttg ttgtacctcc
     1441 cggagcatgg ggtgattgga ttaatggcgg cggatggtta gtcataaacg ggtatcatgt
     1501 ggatttaatt ttacgtgata ttaaacgtgt ggaacaaata atgaaagata cagagcacgg
     1561 aattgttact gccaattatc agactgggca tccccatggt tatattagtg caatgtatcg
     1621 aggagaatta gcgattagca aaatactata tgctaagaat gaaagcttat gcgaattaaa
     1681 aaaacaggca gaaacttatc ccaatgcttt gcagaaaagt ttagttaact tttttatgtt
     1741 tgaagcaggg ttctctttaa tgtttgtaaa agcaaattcg ggaacagacg ataaatatta
     1801 tattgcgggt catgtttttc gtatagtttc atgtttaaat caagtgttat ttgcatgtaa
     1861 taatgcttat tgtatcaacg aaaagaaagc tataaaactg cttgaaactt ttgaacataa
     1921 acctgaaaaa tataccgaga aggtaaatca tatttttgaa gtactcggta tctcactttt
     1981 tgaatgctac gacatgaccg agaagcttta taatgaagtg aatgaaattg tatcggagat
     2041 aaataacttt ttaaacgagg agagttcaga tgaaagaaaa caaatatgat gataatatat
     2101 tttttcaaaa atacagtcaa atgagtcgct cgcagaaagg actggctggt gcgggagaat
     2161 gggagacttt gaaaaagatg ctacctgatt ttaagggtaa gcgtgtgctt gatttaggat
     2221 gcggctatgg atggcactgt atatatgcga tggaaaacgg tgcttcctct gtagtaggtg
     2281 ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa aacccatttt ccacagattg
     2341 aatatgaatg ctgtgccata gaagatgtgg atttcccaga ggagagcttt gatgtaatac
     2401 taagttcgct tgcgtttcat tatgtagcag actatgagaa tttaataaaa aagatatata
     2461 ggatgctgaa ggctggtggc aatttagttt ttacagttga acatcctgtt tttactgctc
     2521 atggaacaca agactggtat tataacgaaa aaggagaaat actgcatttc ccggtggaca
     2581 attattatta tgagggcaaa cggacagcta tgtttttgga agaaaaggtt acaaaatatc
     2641 atagaacact gaccacatat ctaaatacac tgctttcaaa tagttttata ataaatcaga
     2701 ttgtggagcc acagccgcca gagaacatga tggatattcc ggggatggcg gatgaaatgc
     2761 gacgcccaat gatgctgatt gtatcggcaa aaaagaagat gtaataatat agaaaaaata
     2821 aacgaggagt atgtaaatga gatcagaaaa agaaatgatg gatttagtac tttctttagc
     2881 agaacaggat gaacgtattc gaattgtgac ccttgagggg tcacgcgcaa atattaatat
     2941 acctaaagat gaatttcagg attatgatat tacatatttt gtaagtgata tagaaccgtt
     3001 tatatctaat gatgactggc ttaatcaatt tgggaatata ataatgatgc aaaagccgga
     3061 ggatatggaa ttattcccac ctgaagaaaa gggattttcc tatcttatgc tatttgatga
     3121 ttacaataaa attgatctta ccttattgcc cttggaagag ttagataatt acctaaaggg
     3181 cgataaatta ataaaggttc taattgataa agattgtaga attaaaaggg acatagttcc
     3241 gactgatata gattatcatg taagaaagcc aagcgcaagg gagtatgatg attgctgcaa
     3301 tgaattttgg aatgtaacac cttatgttat taaaggattg tgccgtaagg aaattttatt
     3361 tgctattgat cattttaatc agattgttcg ccatgagctg ctgagaatga tatcatggaa
     3421 gggcggcatc gaaacaggct ttaaattaag tgtaggcaag aactataagt ttattgaaag
     3481 gtatatatcc gaggatttgt gggagaaact tttgtccacc taccggatgg attcctatga
     3541 aaacatatgg gaagcattat ttctatgcca tcaattgttc agggcggtat ccggtgaggt
     3601 ggcggaaagg cttcattatg cctatccgga gtatgatagg aatataacaa aatataccag
     3661 ggacatgtat aaaaaataca ctggtaaaac cggctgcctg gatagcacat atgccgctga
     3721 tatagaagag aggcgggaac agtgattaca gaaatgaaag cagggcacct gaaagatatc
     3781 gataaaccca gcgaaccatt tgaggtgata ggtaagatta taccgaggta tgaaaacgag
     3841 aattggacct ttacagaatt actctatgaa gcgccatatt taaaaagcta ccaagacgaa
     3901 gaggatgaag aggatgagga ggcagattgc cttgaatata ttgacaatac tgataagata
     3961 atatatcttt actaccaaga cgataaatgc gtcggaaaag ttaaactgcg aaaaaattgg
     4021 aaccggtacg cttatataga agatatcgcc gtatgtaagg atttcagggg gcaaggcata
     4081 ggcagcgcgc ttatcaatat atctatagaa tgggcaaagc ataaaaactt gcatggacta
     4141 atgcttgaaa cccaggacaa taaccttata gcttgtaaat tctatcataa ttgtggtttc
     4201 aaaatcggct ccgtcgatac tatgttatac gccaactttg aaaacaactt tgaaaaagct
     4261 gttttctggt atttaaggtt ttagaatgca aggaacagtg aattggagtt cgtcttgtta
     4321 taattagctt cttggggtat ctttaaatac tgtagaaaag aggaaggaaa taataaatgg
     4381 ctaaaatgag aatatcaccg gaattgaaaa aactgatcga aaaataccgc tgcgtaaaag
     4441 atacggaagg aatgtctcct gctaaggtat ataagctggt gggagaaaat gaaaacctat
     4501 atttaaaaat gacggacagc cggtataaag ggaccaccta tgatgtggaa cgggaaaagg
     4561 acatgatgct atggctggaa ggaaagctgc ctgttccaaa ggtcctgcac tttgaacggc
     4621 atgatggctg gagcaatctg ctcatgagtg aggccgatgg cgtcctttgc tcggaagagt
     4681 atgaagatga acaaagccct gaaaagatta tcgagggttc tgttgcaaag ttttaaatct
     4741 actatcaaat aaggt
//
LOCUS       DAJSMK010000238         1949 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.179, whole genome shotgun sequence.
ACCESSION   DAJSMK010000238 DAJSMK010000000
VERSION     DAJSMK010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.179"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            45..437
                     /locus_tag="ON488_002836"
     CDS             45..437
                     /locus_tag="ON488_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232930.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            438..1877
                     /locus_tag="ON488_002837"
                     /note="aph(2'')-Ia"
     CDS             438..1877
                     /locus_tag="ON488_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HCR3232931.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          807 a          148 c          337 g          657 t
ORIGIN      
        1 cattgtatag cattttacac aggagtctgg acttgactga gtttatggaa gaagttttaa
       61 ttgatgataa tatggttttt gatattgata atttaaaagg atttcttaat gataccagtt
      121 catttgggtt tatagctaaa gaaaataata aaattatagg atttgcatat tgctatacac
      181 ttttaagacc tgatggaaaa acaatgtttt atttacactc aataggaatg ttacctaact
      241 atcaagacaa aggttatggt tcaaaattat tatcttttat taaggaatat tctaaagaga
      301 ttggttgttc tgaaatgttt ttaataactg ataaaggtaa tcctagagct tgccatgtat
      361 atgaaaaatt aggtggtaaa aatgattata aagatgaaat agtatatgta tatgattatg
      421 aaaaaggtga taaataaatg aatatagttg aaaatgaaat atgtataaga actttaatag
      481 atgatgattt tcctttgatg ttaaaatggt taactgatga aagagtatta gaattttatg
      541 gtggtagaga taaaaaatat acattagaat cattaaaaaa acattataca gagccttggg
      601 aagatgaagt ttttagagta attattgaat ataacaatgt tcctattgga tatggacaaa
      661 tatataaaat gtatgatgag ttatatactg attatcatta tccaaaaact gatgagatag
      721 tctatggtat ggatcaattt ataggagagc caaattattg gagtaaagga attggtacaa
      781 gatatattaa attgattttt gaatttttga aaaaagaaag aaatgctaat gcagttattt
      841 tagaccctca taaaaataat ccaagagcaa taagggcata ccaaaaatct ggttttagaa
      901 ttattgaaga tttgccagaa catgaattac acgagggcaa aaaagaagat tgttatttaa
      961 tggaatatag atatgatgat aatgccacaa atgttaaggc aatgaaatat ttaattgagc
     1021 attactttga taatttcaaa gtagatagta ttgaaataat cggtagtggt tatgatagtg
     1081 tggcatattt agttaataat gaatacattt ttaaaacaaa atttagtact aataagaaaa
     1141 aaggttatgc aaaagaaaaa gcaatatata attttttaaa tacaaattta gaaactaatg
     1201 taaaaattcc taatattgaa tattcgtata ttagtgatga attatctata ctaggttata
     1261 aagaaattaa aggaactttt ttaacaccag aaatttattc tactatgtca gaagaagaac
     1321 aaaatttgtt aaaacgagat attgccagtt ttttaagaca aatgcacggt ttagattata
     1381 cagatattag tgaatgtact attgataata aacaaaatgt attagaagag tatatattgt
     1441 tgcgtgaaac tatttataat gatttaactg atatagaaaa agattatata gaaagtttta
     1501 tggaaagact aaatgcaaca acagtttttg agggtaaaaa gtgtttatgc cataatgatt
     1561 ttagttgtaa tcatctattg ttagatggca ataatagatt aactggaata attgattttg
     1621 gagattctgg aattatagat gaatattgtg attttatata cttacttgaa gatagtgaag
     1681 aagaaatagg aacaaatttt ggagaagata tattaagaat gtatggaaat atagatattg
     1741 agaaagcaaa agaatatcaa gatatagttg aagaatatta tcctattgaa actattgttt
     1801 atggaattaa aaatattaaa caggaattta tcgaaaatgg tagaaaagaa atttataaaa
     1861 ggacttataa agattgatta tataatatat gaaaagctat tataaaagac attgataaag
     1921 tccgtataat tgtgtaaaag taaaaaggc
//
LOCUS       DAJSMK010000239         1949 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.180, whole genome shotgun sequence.
ACCESSION   DAJSMK010000239 DAJSMK010000000
VERSION     DAJSMK010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1949
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.180"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            45..437
                     /locus_tag="ON488_002838"
     CDS             45..437
                     /locus_tag="ON488_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HCR3232932.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            438..1877
                     /locus_tag="ON488_002839"
                     /note="aph(2'')-Ia"
     CDS             438..1877
                     /locus_tag="ON488_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HCR3232933.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATSVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          806 a          148 c          337 g          658 t
ORIGIN      
        1 cattgtatag cattttacac aggagtctgg acttgactga gtttatggaa gaagttttaa
       61 ttgatgataa tatggttttt gatattgata atttaaaagg atttcttaat gataccagtt
      121 catttgggtt tatagctaaa gaaaataata aaattatagg atttgcatat tgctatacac
      181 ttttaagacc tgatggaaaa acaatgtttt atttacactc aataggaatg ttacctaact
      241 atcaagacaa aggttatggt tcaaaattat tatcttttat taaggaatat tctaaagaga
      301 ttggttgttc tgaaatgttt ttaataactg ataaaggtaa tcctagagct tgccatgtat
      361 atgaaaaatt aggtggtaaa aatgattata aagatgaaat agtatatgta tatgattatg
      421 aaaaaggtga taaataaatg aatatagttg aaaatgaaat atgtataaga actttaatag
      481 atgatgattt tcctttgatg ttaaaatggt taactgatga aagagtatta gaattttatg
      541 gtggtagaga taaaaaatat acattagaat cattaaaaaa acattataca gagccttggg
      601 aagatgaagt ttttagagta attattgaat ataacaatgt tcctattgga tatggacaaa
      661 tatataaaat gtatgatgag ttatatactg attatcatta tccaaaaact gatgagatag
      721 tctatggtat ggatcaattt ataggagagc caaattattg gagtaaagga attggtacaa
      781 gatatattaa attgattttt gaatttttga aaaaagaaag aaatgctaat gcagttattt
      841 tagaccctca taaaaataat ccaagagcaa taagggcata ccaaaaatct ggttttagaa
      901 ttattgaaga tttgccagaa catgaattac acgagggcaa aaaagaagat tgttatttaa
      961 tggaatatag atatgatgat aatgccacaa atgttaaggc aatgaaatat ttaattgagc
     1021 attactttga taatttcaaa gtagatagta ttgaaataat cggtagtggt tatgatagtg
     1081 tggcatattt agttaataat gaatacattt ttaaaacaaa atttagtact aataagaaaa
     1141 aaggttatgc aaaagaaaaa gcaatatata attttttaaa tacaaattta gaaactaatg
     1201 taaaaattcc taatattgaa tattcgtata ttagtgatga attatctata ctaggttata
     1261 aagaaattaa aggaactttt ttaacaccag aaatttattc tactatgtca gaagaagaac
     1321 aaaatttgtt aaaacgagat attgccagtt ttttaagaca aatgcacggt ttagattata
     1381 cagatattag tgaatgtact attgataata aacaaaatgt attagaagag tatatattgt
     1441 tgcgtgaaac tatttataat gatttaactg atatagaaaa agattatata gaaagtttta
     1501 tggaaagact aaatgcaaca tcagtttttg agggtaaaaa gtgtttatgc cataatgatt
     1561 ttagttgtaa tcatctattg ttagatggca ataatagatt aactggaata attgattttg
     1621 gagattctgg aattatagat gaatattgtg attttatata cttacttgaa gatagtgaag
     1681 aagaaatagg aacaaatttt ggagaagata tattaagaat gtatggaaat atagatattg
     1741 agaaagcaaa agaatatcaa gatatagttg aagaatatta tcctattgaa actattgttt
     1801 atggaattaa aaatattaaa caggaattta tcgaaaatgg tagaaaagaa atttataaaa
     1861 ggacttataa agattgatta tataatatat gaaaagctat tataaaagac attgataaag
     1921 tccgtataat tgtgtaaaag taaaaaggc
//
LOCUS       DAJSMK010000240         1289 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.208, whole genome shotgun sequence.
ACCESSION   DAJSMK010000240 DAJSMK010000000
VERSION     DAJSMK010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1289
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.208"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            574..1122
                     /gene="aac(6')"
                     /locus_tag="ON488_002840"
     CDS             574..1122
                     /gene="aac(6')"
                     /locus_tag="ON488_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HCR3232934.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT          455 a          188 c          257 g          389 t
ORIGIN      
        1 ctaaaattta tatcttgact tattaccatt aggctttctt cgttgaaacg ggttaaaatt
       61 ttaaagagtg atcgatctga ctgcggctgt agatggagta gaggtgaacc taagacagga
      121 taagtgatga ataaggtggc atgaacacct tgaaatcatc aataagtatc ctaaaaacga
      181 acaagtacaa aaacattgaa aacgacaata atgaattttt gttcctctta gtatttctac
      241 cgattccctt tgcttttttg taattatcta aaaattctaa aaattaagat tattatatga
      301 aaacaggttt tatttgtcaa ttcataattg gtttttttta aagcaaaaga taatctatat
      361 catgatgaac aaacagagtt ttttcctcca attgatggct ttcctgatct ttcctatttt
      421 gaataaagtg tttctgtata atttttttat tttataagta agataaataa tgaaagaata
      481 gagatactga ttggtagcta aagatttttg agcgagaaca tttcgttttt tcaaaaggac
      541 tgttagaata agcaagaaca agggggaaga cgtatgataa tcagtgaatt tgaccgtaat
      601 aatccagtat tgaaagatca gctttctgat ttactgagac tgacttggcc ggaagaatat
      661 ggagacagct cggcagaaga agtagaagaa atgatgaatc cagaacgaat cgcggtagca
      721 gcggtagacc aagatgagtt agtaggattt attggtgcaa tccctcaata cggtatcaca
      781 ggttgggaat tgcatccatt agttgtagaa agctcccgac gaaagaacca aataggtact
      841 cgattagtca attacttaga aaaagaagta gcttccagag gaggaatcac gatttattta
      901 ggtacggatg atttagacca tggaacaacg ttaagtcaaa cggacctgta tgagcataca
      961 tttgataaag tggcttccat ccagaacctt cgtgaacatc cgtatgaatt ctatgaaaaa
     1021 ttaggttata aaatcgtagg tgtcttacca aatgcaaatg gctgggacaa accggatatt
     1081 tggatggcaa aaacgattat tcctcgacca aattctcaat aataaaaaga ggttgtgaca
     1141 gaagtaatca gcttcaagaa ataagaagga atttacgaaa attacttctt gaatttttgt
     1201 gaaattccaa cttatttccg aagaagctac ttttggaaca ccgtgtacca gaggttgtga
     1261 aaaagtcgct tagtttcgag tagtaagaa
//
LOCUS       DAJSMK010000241         1074 bp    DNA     linear   BCT 02-NOV-2022
DEFINITION  TPA_asm: Enterococcus faecium strain AUSMDU00051143
            SAMN29549333-rid15783063.guided.214, whole genome shotgun sequence.
ACCESSION   DAJSMK010000241 DAJSMK010000000
VERSION     DAJSMK010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN29549333
            Sequence Read Archive: SRR20032946
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (02-NOV-2022) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 02-NOV-2022
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001474394.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001474394.1
            Genome Coverage       :: 226x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/03/2022 01:19:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,842
            CDSs (total)                      :: 2,778
            Genes (coding)                    :: 2,709
            CDSs (with protein)               :: 2,709
            Genes (RNA)                       :: 64
            rRNAs                             :: 1, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 55
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 69
            CDSs (without protein)            :: 69
            Pseudo Genes (ambiguous residues) :: 0 of 69
            Pseudo Genes (frameshifted)       :: 33 of 69
            Pseudo Genes (incomplete)         :: 27 of 69
            Pseudo Genes (internal stop)      :: 18 of 69
            Pseudo Genes (multiple problems)  :: 9 of 69
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN29549333-rid15783063.guided.214"
                     /strain="AUSMDU00051143"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Australia"
                     /collection_date="2010"
     gene            110..193
                     /locus_tag="ON488_002841"
     CDS             110..193
                     /locus_tag="ON488_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HCR3232935.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            318..1055
                     /gene="erm(B)"
                     /locus_tag="ON488_002842"
     CDS             318..1055
                     /gene="erm(B)"
                     /locus_tag="ON488_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HCR3232936.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          403 a          173 c          166 g          332 t
ORIGIN      
        1 cttatttgat agtagattta aaactttgca acagaaccat tttgtgtata ataggaattg
       61 aagttaaatt agatgctaaa aatttgtaat taagaaggag ggattcgtca tgttggtatt
      121 ccaaatgcgt aatgtagata aaacatctac tgttttgaaa cagactaaaa acagtgatta
      181 cgcagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
      241 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttac agatgtaata
      301 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
      361 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
      421 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
      481 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
      541 ttcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
      601 ataaaattgt tgggagtatt ccttaccatt taagcacaca aattattaaa aaagtggttt
      661 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
      721 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
      781 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
      841 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
      901 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
      961 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
     1021 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt tttt
//
